# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Ribosomal_L1 PF00687.21 ORX62488.1 - 6.4e-48 163.2 1.3 9.4e-48 162.7 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family HMA PF00403.26 ORX62498.1 - 2.2e-15 56.8 0.8 2.5e-15 56.7 0.8 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain NapD PF03927.13 ORX62498.1 - 0.0045 17.0 0.2 0.0056 16.7 0.2 1.1 1 0 0 1 1 1 1 NapD protein Fer2_BFD PF04324.15 ORX62498.1 - 0.056 13.8 1.8 0.22 11.9 0.1 2.2 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_S8 PF00082.22 ORX62499.1 - 3e-11 43.1 0.3 3.2e-11 43.1 0.3 1.0 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 ORX62500.1 - 3.7e-36 124.9 18.8 1.2e-35 123.3 18.8 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX62500.1 - 1.8e-07 31.7 0.2 3.6e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX62500.1 - 0.027 14.5 0.3 0.05 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Inhibitor_I9 PF05922.16 ORX62501.1 - 1.7e-07 31.8 0.1 3.1e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 ORX62501.1 - 9.1e-05 21.9 1.3 0.022 14.1 0.0 2.2 1 1 1 2 2 2 2 Subtilase family GPCR_chapero_1 PF11904.8 ORX62513.1 - 1.5e-09 37.7 0.0 4.9e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 ORX62513.1 - 0.02 15.5 0.1 0.065 13.8 0.1 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX62513.1 - 0.031 14.8 0.5 0.33 11.6 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 ORX62513.1 - 0.039 14.4 0.7 0.17 12.4 0.4 2.2 2 0 0 2 2 2 0 Ankyrin repeat YL1 PF05764.13 ORX62513.1 - 0.09 12.9 0.6 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CHAP PF05257.16 ORX62514.1 - 2.7e-09 37.4 3.4 4.4e-09 36.8 3.4 1.3 1 0 0 1 1 1 1 CHAP domain Protoglobin PF11563.8 ORX62523.1 - 1.8e-11 44.2 0.0 2.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Protoglobin tRNA-synt_1e PF01406.19 ORX62523.1 - 0.018 14.4 0.4 0.023 14.1 0.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Protoglobin PF11563.8 ORX62524.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Protoglobin MFS_1 PF07690.16 ORX63229.1 - 1e-46 159.5 27.8 1.3e-46 159.1 23.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX63229.1 - 1e-12 47.7 26.2 1e-10 41.1 8.4 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.13 ORX63229.1 - 3e-07 29.2 5.7 3e-07 29.2 5.7 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORX63229.1 - 0.00094 17.6 7.8 0.00094 17.6 7.8 3.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 ORX63229.1 - 0.044 12.7 4.4 0.044 12.7 2.0 2.1 2 1 0 2 2 2 0 Sugar-tranasporters, 12 TM RNA_pol_A_CTD PF03118.15 ORX63237.1 - 0.089 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORX63238.1 - 0.068 12.9 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORX63239.1 - 0.087 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORX63240.1 - 0.23 11.2 0.0 2.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORX63241.1 - 0.086 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Pirin PF02678.16 ORX63245.1 - 1.8e-31 108.3 0.1 3.8e-31 107.3 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORX63245.1 - 4.7e-30 104.0 0.0 8.2e-29 100.0 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORX63245.1 - 0.0042 16.8 3.2 0.041 13.6 1.4 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 ORX63245.1 - 0.14 11.9 0.4 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) WD40 PF00400.32 ORX63246.1 - 4.4e-14 52.7 0.0 0.069 14.0 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX63246.1 - 2.3e-10 40.6 0.0 0.29 11.5 0.0 5.7 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORX63246.1 - 0.00012 20.7 0.2 0.00096 17.8 0.1 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 ORX63246.1 - 0.0048 16.8 0.1 1.8 8.6 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 ORX63246.1 - 0.017 13.9 0.2 0.049 12.4 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4394 PF14339.6 ORX63246.1 - 0.032 13.6 0.1 0.6 9.4 0.0 2.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4394) Fer4_17 PF13534.6 ORX63247.1 - 3.5e-11 43.5 6.8 4.4e-11 43.1 6.8 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORX63247.1 - 3.9e-08 33.6 7.1 7.6e-08 32.7 7.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORX63247.1 - 1.2e-07 31.8 3.7 1.7e-07 31.2 3.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ORX63247.1 - 4.9e-05 23.8 6.5 9.8e-05 22.9 6.5 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 ORX63247.1 - 0.0017 18.5 7.4 0.0033 17.5 7.4 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 ORX63247.1 - 0.056 14.2 1.1 4 8.2 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 ORX63247.1 - 0.23 12.0 4.7 0.76 10.4 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 ORX63247.1 - 0.36 11.4 7.6 0.76 10.4 1.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 ORX63247.1 - 0.73 9.8 11.9 5.8 6.9 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 ORX63247.1 - 4.1 8.6 15.4 14 6.9 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF775 PF05603.12 ORX63265.1 - 1.9e-37 128.7 0.5 2.5e-37 128.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) zf-C2H2 PF00096.26 ORX63266.1 - 7.9e-10 38.7 9.5 0.00018 21.8 2.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX63266.1 - 3.5e-08 33.6 7.9 0.0019 18.9 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX63266.1 - 8.1e-07 29.2 12.8 3e-06 27.4 3.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORX63266.1 - 0.003 17.3 3.6 0.035 13.9 0.0 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.7 ORX63266.1 - 0.0054 17.1 0.6 0.043 14.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX63266.1 - 0.013 15.7 0.4 0.031 14.6 0.4 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORX63266.1 - 0.046 14.4 0.4 0.088 13.5 0.1 1.6 1 1 1 2 2 2 0 FOXP coiled-coil domain RPAP2_Rtr1 PF04181.13 ORX63266.1 - 0.088 13.1 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_6 PF13912.6 ORX63266.1 - 0.31 11.1 4.3 1.4 9.0 0.3 2.7 2 2 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX63266.1 - 0.47 10.8 2.9 1 9.8 0.8 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Keratin_2_head PF16208.5 ORX63272.1 - 0.0034 17.6 8.3 0.0037 17.4 8.3 1.0 1 0 0 1 1 1 1 Keratin type II head Trypan_PARP PF05887.11 ORX63272.1 - 4.1 7.4 36.2 8 6.4 36.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cyclin PF08613.11 ORX63273.1 - 1.8e-10 41.4 0.0 2.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX63273.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Uricase PF01014.18 ORX63288.1 - 5.6e-17 62.2 0.1 6.8e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Uricase Uricase PF01014.18 ORX63289.1 - 1e-16 61.4 0.1 1.2e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Uricase zf-H2C2_2 PF13465.6 ORX63290.1 - 2.4e-11 43.5 5.0 1.3e-08 34.9 0.7 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX63290.1 - 1.2e-06 28.7 10.6 8.4e-06 26.0 3.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX63290.1 - 4.3e-06 27.1 8.7 0.00012 22.6 2.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX63290.1 - 0.064 13.3 6.8 0.26 11.3 1.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX63290.1 - 0.067 13.0 3.7 0.13 12.0 0.4 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_4 PF07975.12 ORX63290.1 - 0.13 12.5 5.8 2.7 8.3 5.9 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 ORX63290.1 - 0.77 9.7 6.0 1.5 8.8 1.3 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 ORX63290.1 - 0.77 9.4 5.7 0.32 10.6 0.9 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain Velvet PF11754.8 ORX63291.1 - 7.4e-59 199.7 0.0 1.5e-34 120.1 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Glyco_transf_25 PF01755.17 ORX63302.1 - 0.084 12.7 1.7 5.2 6.9 1.7 2.2 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) DPBB_1 PF03330.18 ORX63313.1 - 1.2e-09 38.4 0.0 2.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX63313.1 - 0.026 14.4 0.1 0.099 12.5 0.0 1.9 2 0 0 2 2 2 0 Barwin family DPBB_1 PF03330.18 ORX63314.1 - 1.4e-10 41.3 0.1 2.4e-10 40.6 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX63314.1 - 0.062 13.1 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Barwin family DUF3039 PF11238.8 ORX63314.1 - 0.09 12.5 1.4 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) DPBB_1 PF03330.18 ORX63315.1 - 3.7e-06 27.1 0.1 9.6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Lytic transglycolase DUF2486 PF10667.9 ORX63315.1 - 0.031 14.5 1.2 0.041 14.1 1.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2486) CBM_14 PF01607.24 ORX63315.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.8 3 1 0 3 3 3 0 Chitin binding Peritrophin-A domain RGS PF00615.19 ORX63327.1 - 0.021 15.1 1.5 0.035 14.4 1.5 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain Pam17 PF08566.10 ORX63327.1 - 0.25 11.2 0.9 0.52 10.1 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 RGS PF00615.19 ORX63328.1 - 3.7e-13 49.8 2.5 6.2e-13 49.1 2.5 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX63329.1 - 2e-14 53.8 1.7 3.4e-14 53.1 1.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX63330.1 - 5.6e-14 52.4 2.7 9.4e-14 51.7 2.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Topo_C_assoc PF14370.6 ORX63351.1 - 1.1e-36 124.6 2.2 2e-36 123.8 2.2 1.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4998 PF16389.5 ORX63351.1 - 0.023 14.3 0.5 0.033 13.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function Intein_splicing PF14890.6 ORX63351.1 - 0.097 12.6 0.4 0.37 10.8 0.0 1.8 1 1 1 2 2 2 0 Intein splicing domain HAGH_C PF16123.5 ORX63352.1 - 1.5e-26 92.7 0.0 2.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORX63352.1 - 4.3e-13 49.7 0.7 3.4e-12 46.8 0.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ORX63352.1 - 0.00046 20.1 0.1 0.0013 18.6 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ORX63352.1 - 0.00062 19.3 1.1 0.011 15.2 0.4 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RPEL PF02755.15 ORX63353.1 - 1.4e-19 69.1 5.3 2.3e-08 33.4 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat CCDC84 PF14968.6 ORX63353.1 - 0.003 17.3 0.2 0.0033 17.1 0.2 1.1 1 0 0 1 1 1 1 Coiled coil protein 84 Sugar_tr PF00083.24 ORX63363.1 - 1e-47 163.1 17.9 1.2e-47 162.8 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX63363.1 - 3.7e-20 72.2 22.9 1.9e-19 69.8 21.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX63363.1 - 9.1e-06 25.2 2.3 2e-05 24.1 2.3 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF417 PF04224.12 ORX63363.1 - 0.0056 16.3 0.7 0.0056 16.3 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORX63363.1 - 0.17 10.1 6.1 0.041 12.2 0.9 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family S-AdoMet_synt_M PF02772.16 ORX63382.1 - 2.5e-47 160.1 0.0 5.2e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORX63382.1 - 5.9e-46 155.2 0.1 1.3e-45 154.1 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORX63382.1 - 0.0078 15.0 0.4 0.039 12.7 0.1 1.9 1 1 1 2 2 2 1 S-adenosylmethionine synthetase (AdoMet synthetase) S-AdoMet_synt_C PF02773.16 ORX63383.1 - 1.5e-68 229.1 0.1 3.3e-68 228.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORX63383.1 - 7.7e-47 158.5 0.0 1.4e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORX63383.1 - 1.6e-45 153.8 0.1 3.2e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORX63383.1 - 0.023 13.5 0.4 0.08 11.7 0.1 1.8 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) CASP_C PF08172.12 ORX63384.1 - 1.8e-59 201.1 15.1 1.8e-59 201.1 15.1 5.5 2 2 1 4 4 3 1 CASP C terminal Golgin_A5 PF09787.9 ORX63384.1 - 6.6e-05 22.5 62.1 0.0005 19.6 10.2 4.0 1 1 2 3 3 3 2 Golgin subfamily A member 5 ADIP PF11559.8 ORX63384.1 - 0.00035 20.7 13.1 0.0075 16.4 10.9 5.4 3 1 1 5 5 5 2 Afadin- and alpha -actinin-Binding PKcGMP_CC PF16808.5 ORX63384.1 - 0.00092 19.0 1.0 0.00092 19.0 1.0 5.9 6 0 0 6 6 6 2 Coiled-coil N-terminus of cGMP-dependent protein kinase PRKG1_interact PF15898.5 ORX63384.1 - 0.013 16.4 8.6 0.013 16.4 8.6 5.6 2 2 3 5 5 5 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 ORX63384.1 - 0.058 12.9 64.4 0.27 10.7 8.2 4.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 ORX63384.1 - 0.72 10.1 60.9 1.8 8.8 9.1 6.5 3 1 3 6 6 6 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ORX63384.1 - 0.8 10.1 60.5 0.36 11.2 26.6 3.4 1 1 1 2 2 2 0 Fez1 Filament PF00038.21 ORX63384.1 - 1.1 8.8 58.5 0.067 12.8 13.5 4.4 2 1 2 4 4 4 0 Intermediate filament protein IFT46_B_C PF12317.8 ORX63384.1 - 2.6 7.7 15.2 13 5.5 0.5 3.3 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal MscS_porin PF12795.7 ORX63384.1 - 3.2 7.2 54.1 0.23 11.0 7.6 4.6 2 1 1 4 4 4 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 ORX63384.1 - 4 6.7 42.2 2.2 7.5 17.4 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 ORX63384.1 - 8.2 6.5 69.7 1.2 9.1 0.2 5.7 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Septin PF00735.18 ORX63385.1 - 3.8e-110 367.6 0.0 4.6e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORX63385.1 - 6.9e-06 26.1 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORX63385.1 - 2.5e-05 24.4 0.0 0.1 12.7 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 ORX63385.1 - 0.00099 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 ORX63385.1 - 0.0031 17.4 0.1 0.039 13.9 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORX63385.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Aldo_ket_red PF00248.21 ORX63386.1 - 1e-50 172.6 0.3 5.7e-50 170.2 0.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family TetR_C_5 PF08360.11 ORX63386.1 - 0.029 14.6 0.1 0.061 13.5 0.1 1.6 1 0 0 1 1 1 0 QacR-like protein, C-terminal region DUF3126 PF11324.8 ORX63386.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) EBP PF05241.12 ORX63389.1 - 1.1e-21 77.0 0.0 1.3e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2408 PF10303.9 ORX63419.1 - 3.6e-42 144.1 1.7 5.9e-21 75.4 0.1 4.2 2 1 2 4 4 4 4 Protein of unknown function (DUF2408) Spc7 PF08317.11 ORX63419.1 - 0.006 15.5 0.1 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein V-SNARE PF05008.15 ORX63419.1 - 0.15 12.4 1.2 2.1 8.8 0.1 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus 4HBT PF03061.22 ORX63420.1 - 5.3e-14 52.3 0.0 8.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily PT-VENN PF04829.13 ORX63420.1 - 0.033 14.3 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif HD PF01966.22 ORX63426.1 - 2.8e-05 24.4 0.0 3.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 HD domain RBP_receptor PF14752.6 ORX63428.1 - 2.3e-25 89.2 15.1 3e-25 88.9 15.1 1.1 1 0 0 1 1 1 1 Retinol binding protein receptor adh_short PF00106.25 ORX63429.1 - 1.5e-06 27.8 0.2 8.7e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX63429.1 - 0.00042 19.9 0.0 0.00056 19.5 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Y_phosphatase2 PF03162.13 ORX63430.1 - 0.0043 16.6 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family ORC5_C PF14630.6 ORX63434.1 - 1.4e-67 228.2 0.1 1.8e-67 227.9 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 ORX63434.1 - 2.1e-16 60.8 0.0 4.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX63434.1 - 1.1e-06 28.9 0.0 8.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORX63434.1 - 0.0061 16.6 0.0 0.038 14.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORX63434.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 ORX63434.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 ORX63434.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.22 ORX63435.1 - 1.4e-21 76.1 0.3 1e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX63435.1 - 6.8e-06 25.8 0.2 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF1027 PF06265.11 ORX63435.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) PHM7_cyt PF14703.6 ORX63435.1 - 0.081 13.2 1.6 13 6.0 0.4 2.6 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 ORX63435.1 - 0.093 12.9 0.1 14 5.9 0.1 2.5 2 1 0 2 2 2 0 RNA recognition motif Peptidase_S10 PF00450.22 ORX63449.1 - 4.4e-51 174.6 0.0 5e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RasGAP PF00616.19 ORX63453.1 - 1.4e-56 191.5 1.1 1.4e-56 191.5 1.1 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORX63453.1 - 2.2e-41 141.2 10.9 2.3e-41 141.1 6.9 3.1 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 ORX63453.1 - 1.1e-25 86.9 27.0 0.029 14.2 0.0 11.0 11 0 0 11 11 11 9 IQ calmodulin-binding motif Nkap_C PF06047.11 ORX63470.1 - 1.3e-30 105.5 3.6 4.1e-28 97.5 1.1 2.0 1 1 1 2 2 2 2 NF-kappa-B-activating protein C-terminal domain GATA PF00320.27 ORX63488.1 - 4.7e-18 64.5 5.6 6.7e-18 64.0 5.6 1.2 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 ORX63488.1 - 0.017 15.2 0.7 0.029 14.5 0.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 ORX63488.1 - 0.024 14.8 0.3 0.03 14.5 0.3 1.2 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_9 PF14369.6 ORX63488.1 - 0.062 13.6 1.3 0.14 12.5 1.3 1.5 1 0 0 1 1 1 0 zinc-ribbon MIS13 PF08202.11 ORX63489.1 - 3.4e-39 134.9 10.6 3.4e-39 134.9 10.6 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family HisK_sensor PF18698.1 ORX63489.1 - 0.013 15.8 1.5 0.013 15.8 1.5 2.2 2 0 0 2 2 2 0 Histidine kinase sensor domain SNF2_N PF00176.23 ORX63497.1 - 1.2e-24 86.7 0.3 1.9e-24 86.0 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORX63497.1 - 0.0026 17.8 0.2 0.0049 16.9 0.2 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HAUS4 PF14735.6 ORX63497.1 - 0.17 11.6 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Kelch_5 PF13854.6 ORX63497.1 - 0.32 11.0 3.7 2.9 8.0 0.1 2.8 3 0 0 3 3 3 0 Kelch motif AAA PF00004.29 ORX63532.1 - 2.7e-17 63.4 0.0 3.3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX63532.1 - 7.3e-05 23.2 0.0 0.0001 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ORX63532.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 ORX63532.1 - 0.00037 19.8 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORX63532.1 - 0.00049 19.9 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORX63532.1 - 0.00079 19.8 0.0 0.0013 19.1 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 ORX63532.1 - 0.00099 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ORX63532.1 - 0.0044 16.7 0.1 0.011 15.5 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX63532.1 - 0.005 16.9 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 ORX63532.1 - 0.0095 16.5 0.0 0.014 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX63532.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORX63532.1 - 0.019 14.9 0.0 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 ORX63532.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 ORX63532.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 ORX63532.1 - 0.025 14.9 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORX63532.1 - 0.038 14.0 0.0 0.071 13.1 0.0 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORX63532.1 - 0.039 14.5 0.0 0.054 14.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 ORX63532.1 - 0.039 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 ORX63532.1 - 0.063 13.2 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 ORX63532.1 - 0.067 12.9 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORX63532.1 - 0.081 12.0 0.0 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 ORX63532.1 - 0.092 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORX63532.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORX63532.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 ORX63532.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 ORX63532.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX63532.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 ORX63532.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 ORX63532.1 - 0.22 10.8 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin NAGPA PF09992.9 ORX63533.1 - 2.9e-10 40.6 0.0 3.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase zf-Mss51 PF13824.6 ORX63533.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2196 PF09962.9 ORX63556.1 - 1.2e-22 79.6 2.5 1.8e-22 79.0 2.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Rad50_zn_hook PF04423.14 ORX63556.1 - 0.14 12.0 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF4469 PF14734.6 ORX63564.1 - 0.00018 21.6 1.0 0.012 15.7 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4469) with IG-like fold DUF4625 PF15418.6 ORX63564.1 - 0.00088 19.5 0.2 5.4 7.3 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4625) DUF1093 PF06486.11 ORX63564.1 - 0.0049 17.5 0.7 2.6 8.8 0.0 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1093) NAR2 PF16974.5 ORX63564.1 - 0.0078 15.6 0.8 0.055 12.9 0.1 2.5 3 0 0 3 3 3 1 High-affinity nitrate transporter accessory GPI-anchored PF10342.9 ORX63564.1 - 0.0095 16.7 0.3 0.0095 16.7 0.3 3.6 4 0 0 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Trypan_PARP PF05887.11 ORX63564.1 - 0.018 15.0 7.4 0.6 10.1 0.4 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CHU_C PF13585.6 ORX63564.1 - 0.021 14.9 1.1 0.26 11.4 0.1 2.7 3 0 0 3 3 3 0 C-terminal domain of CHU protein family CBM_48 PF02922.18 ORX63564.1 - 0.11 12.8 0.2 29 5.1 0.0 3.0 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) LigD_N PF13298.6 ORX63564.1 - 0.14 12.5 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) Trypan_PARP PF05887.11 ORX63565.1 - 1.1e-05 25.5 17.9 0.00011 22.2 9.6 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) GPI-anchored PF10342.9 ORX63565.1 - 0.00013 22.7 1.0 0.00013 22.7 1.0 3.5 4 0 0 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4469 PF14734.6 ORX63565.1 - 0.00039 20.5 1.0 0.016 15.3 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4469) with IG-like fold DUF4625 PF15418.6 ORX63565.1 - 0.0016 18.7 0.1 7.2 6.9 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4625) DUF1093 PF06486.11 ORX63565.1 - 0.012 16.2 0.9 3.4 8.4 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1093) NAR2 PF16974.5 ORX63565.1 - 0.016 14.7 1.0 0.072 12.5 0.1 2.4 3 0 0 3 3 3 0 High-affinity nitrate transporter accessory CHU_C PF13585.6 ORX63565.1 - 0.03 14.4 0.8 0.32 11.1 0.1 2.6 3 0 0 3 3 3 0 C-terminal domain of CHU protein family LigD_N PF13298.6 ORX63565.1 - 0.11 12.8 0.2 21 5.5 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase Ligase (LigD) CBM_48 PF02922.18 ORX63565.1 - 0.15 12.4 0.2 25 5.3 0.0 2.9 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPX PF03105.19 ORX63565.1 - 0.87 9.4 6.4 1.2 9.0 6.4 1.2 1 0 0 1 1 1 0 SPX domain Trypan_PARP PF05887.11 ORX63566.1 - 2.4e-05 24.3 16.7 0.00025 21.0 8.5 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) GPI-anchored PF10342.9 ORX63566.1 - 0.00012 22.7 1.0 0.00012 22.7 1.0 3.5 4 0 0 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4469 PF14734.6 ORX63566.1 - 0.00038 20.6 1.0 0.016 15.3 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4469) with IG-like fold DUF4625 PF15418.6 ORX63566.1 - 0.0015 18.8 0.1 7.2 6.9 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4625) DUF1093 PF06486.11 ORX63566.1 - 0.012 16.3 0.9 3.3 8.4 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1093) NAR2 PF16974.5 ORX63566.1 - 0.015 14.7 1.0 0.072 12.5 0.1 2.4 3 0 0 3 3 3 0 High-affinity nitrate transporter accessory CHU_C PF13585.6 ORX63566.1 - 0.03 14.4 0.8 0.31 11.1 0.1 2.6 3 0 0 3 3 3 0 C-terminal domain of CHU protein family LigD_N PF13298.6 ORX63566.1 - 0.11 12.9 0.2 21 5.5 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase Ligase (LigD) CBM_48 PF02922.18 ORX63566.1 - 0.15 12.4 0.2 25 5.3 0.0 2.9 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPX PF03105.19 ORX63566.1 - 1.2 9.0 6.1 1.7 8.5 6.1 1.2 1 0 0 1 1 1 0 SPX domain PSK_trans_fac PF07704.11 ORX63585.1 - 0.054 14.3 0.1 0.2 12.5 0.0 1.9 2 0 0 2 2 2 0 Rv0623-like transcription factor DUF948 PF06103.11 ORX63585.1 - 0.1 12.9 1.2 5 7.5 0.3 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PocR PF10114.9 ORX63585.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Sensory domain found in PocR THOC7 PF05615.13 ORX63585.1 - 1.6 9.0 4.6 1.5 9.1 0.4 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 PC_rep PF01851.22 ORX63585.1 - 2.4 8.7 5.5 16 6.1 0.8 4.0 4 0 0 4 4 4 0 Proteasome/cyclosome repeat GA PF01468.17 ORX63590.1 - 0.0001 22.5 17.6 1.3 9.3 0.3 6.5 6 0 0 6 6 6 4 GA module GBR2_CC PF18455.1 ORX63590.1 - 0.2 11.8 2.4 23 5.2 0.0 3.9 3 0 0 3 3 3 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain AAA PF00004.29 ORX63604.1 - 6e-62 207.9 0.0 1.4e-43 148.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RabGAP-TBC PF00566.18 ORX63604.1 - 3.5e-27 95.5 0.3 8.6e-27 94.2 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PEX-1N PF09262.11 ORX63604.1 - 4.1e-24 84.8 0.2 1.3e-23 83.2 0.2 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 ORX63604.1 - 1.3e-12 47.3 0.2 3.3e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORX63604.1 - 5.2e-10 40.0 4.8 0.00035 21.0 0.4 4.2 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORX63604.1 - 5.6e-08 33.2 0.6 0.0031 17.8 0.1 3.6 2 2 1 3 3 3 2 AAA domain PEX-2N PF09263.10 ORX63604.1 - 6.4e-07 29.6 0.0 2.3e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal NACHT PF05729.12 ORX63604.1 - 1.8e-06 28.0 0.3 0.0037 17.2 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 ORX63604.1 - 2.2e-06 27.9 0.0 0.05 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORX63604.1 - 2.4e-06 27.5 0.0 0.053 13.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 ORX63604.1 - 2.4e-06 27.6 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 ORX63604.1 - 7.9e-06 26.1 0.0 0.043 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 ORX63604.1 - 1.4e-05 25.1 0.5 0.3 11.1 0.0 3.5 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORX63604.1 - 1.4e-05 25.7 0.0 0.36 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 ORX63604.1 - 1.5e-05 24.8 0.0 0.0032 17.2 0.0 3.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORX63604.1 - 2.6e-05 24.6 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.6 ORX63604.1 - 2.7e-05 24.6 0.0 0.49 10.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORX63604.1 - 3.5e-05 23.0 0.0 0.0002 20.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.6 ORX63604.1 - 0.00011 22.0 0.0 0.0092 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ORX63604.1 - 0.0002 20.7 0.0 0.052 12.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 ORX63604.1 - 0.0002 21.4 0.0 0.017 15.1 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 ORX63604.1 - 0.0012 18.9 0.0 0.94 9.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Molydop_binding PF01568.21 ORX63604.1 - 0.0013 18.8 0.0 2.3 8.3 0.0 3.5 3 0 0 3 3 3 1 Molydopterin dinucleotide binding domain AAA_25 PF13481.6 ORX63604.1 - 0.002 17.7 2.2 8.4 5.9 0.1 4.0 3 1 1 4 4 4 0 AAA domain ABC_tran PF00005.27 ORX63604.1 - 0.0034 17.9 0.0 0.51 10.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 ORX63604.1 - 0.0034 16.7 0.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.17 ORX63604.1 - 0.0041 16.9 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 ORX63604.1 - 0.0049 16.1 0.0 3 7.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.26 ORX63604.1 - 0.0067 16.1 0.0 0.66 9.6 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 ORX63604.1 - 0.0076 15.8 0.0 0.89 9.0 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 ORX63604.1 - 0.0076 15.6 0.0 2.5 7.4 0.0 2.9 3 0 0 3 3 3 1 KaiC AAA_19 PF13245.6 ORX63604.1 - 0.0094 16.3 0.1 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORX63604.1 - 0.01 15.9 0.1 0.037 14.1 0.0 1.9 2 0 0 2 2 1 0 Helicase HerA, central domain Mg_chelatase PF01078.21 ORX63604.1 - 0.011 15.1 0.1 0.97 8.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 ORX63604.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DUF815 PF05673.13 ORX63604.1 - 0.012 14.8 0.0 0.42 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 ORX63604.1 - 0.019 14.1 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain RNA12 PF10443.9 ORX63604.1 - 0.02 13.7 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein Rad17 PF03215.15 ORX63604.1 - 0.027 14.4 0.1 0.65 9.9 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 ORX63604.1 - 0.035 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 ORX63604.1 - 0.053 13.8 0.0 9.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORX63604.1 - 0.063 12.9 0.2 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Bac_DnaA PF00308.18 ORX63604.1 - 0.099 12.5 0.0 7.9 6.2 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein PCI PF01399.27 ORX63605.1 - 7.3e-24 84.3 1.3 7.3e-24 84.3 1.3 2.6 2 1 1 3 3 3 1 PCI domain RAMPs PF03787.15 ORX63605.1 - 0.3 11.1 1.7 0.75 9.8 1.7 1.6 1 0 0 1 1 1 0 RAMP superfamily XPG_I PF00867.18 ORX63606.1 - 3.3e-18 65.8 0.1 1e-17 64.3 0.1 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORX63606.1 - 1e-12 48.4 0.0 2.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 ORX63606.1 - 0.0023 18.5 0.0 0.0076 16.8 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF4746 PF15928.5 ORX63606.1 - 0.016 14.6 0.7 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RdRP PF05183.12 ORX63616.1 - 7.7e-162 540.0 0.0 3.8e-161 537.7 0.0 2.0 3 0 0 3 3 3 1 RNA dependent RNA polymerase PET PF06297.14 ORX63616.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 PET Domain Iron_permease PF04120.12 ORX63617.1 - 8.9e-33 112.8 15.2 1e-13 51.2 0.5 4.2 4 0 0 4 4 4 4 Low affinity iron permease STI1 PF17830.1 ORX63617.1 - 0.094 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 STI1 domain Ribosomal_L10 PF00466.20 ORX63644.1 - 1e-24 86.6 0.7 1.4e-24 86.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORX63644.1 - 1.6e-21 76.0 0.0 2.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P TPR_1 PF00515.28 ORX63645.1 - 1.1e-14 53.5 7.5 7.3e-06 25.6 0.1 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX63645.1 - 9.2e-14 50.4 5.9 6.6e-05 22.7 0.0 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORX63645.1 - 9.5e-12 44.4 2.9 4.5e-06 26.3 0.1 3.4 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 ORX63645.1 - 4.6e-07 29.6 5.2 0.097 12.9 0.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX63645.1 - 6.4e-07 29.8 1.4 2.9e-06 27.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX63645.1 - 6.5e-07 29.6 2.2 0.042 14.1 0.0 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX63645.1 - 7.5e-07 29.5 0.7 0.13 13.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX63645.1 - 2.5e-06 27.5 2.2 0.0011 19.1 2.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX63645.1 - 0.00016 21.5 0.3 1.6 8.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX63645.1 - 0.0016 19.0 1.3 0.029 15.0 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORX63645.1 - 0.012 16.0 3.3 4 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORX63645.1 - 0.022 14.8 2.7 1.1 9.4 0.1 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 ORX63645.1 - 0.036 14.7 1.7 92 4.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX63645.1 - 0.054 13.7 0.3 0.13 12.5 0.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 ORX63645.1 - 0.066 13.3 0.6 0.57 10.2 0.6 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) MAS20 PF02064.15 ORX63645.1 - 0.18 11.9 1.2 0.61 10.2 0.3 2.2 2 1 0 2 2 2 0 MAS20 protein import receptor cwf21 PF08312.12 ORX63645.1 - 0.42 10.8 8.0 0.24 11.6 0.7 2.6 2 0 0 2 2 2 0 cwf21 domain tRNA-synt_1 PF00133.22 ORX63646.1 - 1.2e-158 529.1 0.1 1.5e-157 525.5 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORX63646.1 - 1.5e-39 135.4 0.2 1.6e-38 132.0 0.1 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 ORX63646.1 - 4.2e-07 30.2 2.0 8.8e-07 29.1 2.0 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 ORX63646.1 - 6.6e-07 29.0 0.0 1.7e-05 24.4 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ORX63646.1 - 2e-06 26.8 3.6 0.021 13.6 0.2 3.4 2 1 2 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ORX63646.1 - 0.00098 18.6 0.0 0.0033 16.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ABC_tran_CTD PF16326.5 ORX63646.1 - 0.023 14.9 0.3 0.068 13.4 0.3 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain V-SNARE PF05008.15 ORX63646.1 - 0.06 13.7 0.3 0.32 11.4 0.6 2.0 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus COG2 PF06148.11 ORX63646.1 - 0.07 13.2 0.3 0.31 11.1 0.3 2.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Flagellar_rod PF05149.12 ORX63646.1 - 0.078 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein DivIC PF04977.15 ORX63646.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Matrilin_ccoil PF10393.9 ORX63646.1 - 0.13 12.1 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CCDC-167 PF15188.6 ORX63646.1 - 1.1 9.6 3.8 1.6 9.2 1.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_L16 PF00252.18 ORX63658.1 - 9.5e-44 148.6 0.2 1.2e-43 148.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HLH PF00010.26 ORX63659.1 - 1.8e-14 53.4 3.3 3.8e-14 52.4 3.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SpecificRecomb PF10136.9 ORX63659.1 - 0.11 10.8 0.7 0.14 10.4 0.7 1.1 1 0 0 1 1 1 0 Site-specific recombinase EBP50_C PF09007.11 ORX63659.1 - 1.8 9.5 6.1 0.89 10.6 3.3 1.8 1 1 0 1 1 1 0 EBP50, C-terminal DOPA_dioxygen PF08883.11 ORX63660.1 - 3e-31 107.8 0.1 3.5e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family SPRY PF00622.28 ORX63666.1 - 6.6e-17 61.7 0.1 7.7e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 SPRY domain DUF1883 PF08980.10 ORX63666.1 - 0.068 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) Peptidase_M28 PF04389.17 ORX63667.1 - 1.2e-39 136.0 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX63667.1 - 6.4e-16 58.2 0.2 1.6e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX63667.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORX63667.1 - 0.088 11.8 0.0 2.2 7.2 0.0 2.4 2 1 0 2 2 2 0 M42 glutamyl aminopeptidase CAP PF00188.26 ORX63675.1 - 1.5e-16 61.4 0.0 2.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HSP70 PF00012.20 ORX63712.1 - 4.6e-263 873.9 6.9 5.2e-263 873.7 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX63712.1 - 1.8e-16 59.9 0.1 3.1e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX63712.1 - 0.0044 16.8 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX63712.1 - 0.0084 15.4 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX63712.1 - 0.017 14.7 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX63712.1 - 0.044 14.0 4.9 0.42 10.8 0.8 2.4 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX63712.1 - 0.047 13.7 0.5 0.1 12.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DDR PF08841.10 ORX63712.1 - 0.081 11.9 0.2 0.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 ORX63712.1 - 0.13 11.4 0.7 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 StbA protein Golgin_A5 PF09787.9 ORX63712.1 - 8.9 5.7 9.1 2.3 7.6 5.2 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 CHAP PF05257.16 ORX63723.1 - 4.3e-10 40.0 2.9 6.9e-10 39.4 2.9 1.3 1 0 0 1 1 1 1 CHAP domain Kp4 PF09044.10 ORX63724.1 - 7.4e-28 97.1 4.7 8.9e-28 96.9 4.7 1.0 1 0 0 1 1 1 1 Kp4 Myticin-prepro PF10690.9 ORX63732.1 - 0.0039 17.4 0.3 0.0059 16.8 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel XRCC4 PF06632.12 ORX63733.1 - 0.076 11.9 0.4 0.087 11.7 0.4 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 POT1PC PF16686.5 ORX63741.1 - 4.2e-21 75.4 0.0 1.2e-19 70.7 0.1 2.8 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ORX63741.1 - 7.1e-14 51.9 0.6 1.9e-13 50.5 0.2 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Rep_fac-A_C PF08646.10 ORX63741.1 - 0.0047 16.7 0.0 0.016 14.9 0.0 1.8 1 1 1 2 2 2 1 Replication factor-A C terminal domain C1_1 PF00130.22 ORX63741.1 - 0.075 12.9 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNR_Alpha PF17975.1 ORX63742.1 - 8.7e-41 138.5 1.1 1.7e-40 137.5 0.2 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 ORX63742.1 - 1.6e-09 36.9 0.1 0.00021 20.0 0.0 3.4 4 0 0 4 4 4 3 Ribonucleotide reductase, barrel domain RSN1_7TM PF02714.15 ORX63747.1 - 2.3e-73 246.9 26.2 3e-73 246.5 26.2 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX63747.1 - 4.5e-23 82.4 0.1 5.6e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORX63747.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Ribosomal_L21e PF01157.18 ORX63748.1 - 0.071 13.0 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L21e Epimerase PF01370.21 ORX63749.1 - 6.7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TAF4 PF05236.14 ORX63750.1 - 3.9e-34 118.7 0.3 4.8e-34 118.4 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Cyclin PF08613.11 ORX63761.1 - 1.4e-11 45.0 0.0 2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin ER_lumen_recept PF00810.18 ORX63761.1 - 0.0013 19.5 0.9 0.007 17.2 0.3 1.9 1 1 1 2 2 2 1 ER lumen protein retaining receptor Cyclin_N PF00134.23 ORX63761.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ICL PF00463.21 ORX63762.1 - 6.7e-242 803.6 0.3 8.8e-242 803.2 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORX63762.1 - 5.4e-10 39.1 0.1 9.2e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 ORX63762.1 - 0.025 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Cyt-b5 PF00173.28 ORX63763.1 - 6.3e-22 77.5 0.0 1.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 ORX63764.1 - 6.9e-46 156.2 0.4 2e-45 154.7 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX63764.1 - 5.1e-32 110.5 0.4 5.8e-30 103.9 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Sporozoite_P67 PF05642.11 ORX63764.1 - 0.053 11.6 6.2 0.11 10.6 6.2 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BK_channel_a PF03493.18 ORX63770.1 - 7.8e-19 67.7 0.0 1.5e-16 60.4 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORX63770.1 - 2e-12 46.9 8.2 6.6e-12 45.2 8.2 1.9 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 ORX63770.1 - 2.6e-05 24.5 0.1 0.08 13.2 0.1 2.9 3 0 0 3 3 3 2 TrkA-N domain Lig_chan PF00060.26 ORX63770.1 - 0.82 9.5 6.7 0.048 13.5 0.8 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel Ion_trans PF00520.31 ORX63770.1 - 1.3 8.2 24.9 3.1 7.0 24.9 1.5 1 1 0 1 1 1 0 Ion transport protein NAD_binding_1 PF00175.21 ORX63771.1 - 4e-30 104.7 0.0 6.4e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORX63771.1 - 1.6e-20 73.3 0.0 3.3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORX63771.1 - 1e-08 35.4 0.0 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Adaptin_N PF01602.20 ORX63772.1 - 2.7e-78 263.8 7.0 4e-77 260.0 7.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 ORX63772.1 - 1.6e-06 28.4 0.2 0.0051 17.2 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats DUF5578 PF17741.1 ORX63772.1 - 0.0017 17.9 1.1 0.063 12.7 0.2 2.9 2 1 0 2 2 2 1 Family of unknown function (DUF5578) Cnd1 PF12717.7 ORX63772.1 - 0.0065 16.5 7.5 1.2 9.1 0.5 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORX63772.1 - 0.072 13.4 1.1 12 6.4 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat DUF5010 PF16402.5 ORX63772.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) PRR20 PF15708.5 ORX63779.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 HTH_49 PF18010.1 ORX63779.1 - 0.13 12.2 0.4 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Cry35Ab1 HTH C-terminal domain Aminotran_3 PF00202.21 ORX63780.1 - 8e-120 400.2 0.0 9.3e-120 400.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX63780.1 - 0.0084 15.3 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX63780.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase OAM_dimer PF16554.5 ORX63780.1 - 0.067 13.6 0.5 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Aminotran_3 PF00202.21 ORX63781.1 - 4.3e-120 401.1 0.0 4.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX63781.1 - 0.0083 15.3 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX63781.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase OAM_dimer PF16554.5 ORX63781.1 - 0.067 13.7 0.5 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase ABC2_membrane PF01061.24 ORX63782.1 - 1.4e-65 220.7 63.0 2.1e-42 144.9 27.0 4.0 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORX63782.1 - 1.5e-15 58.0 0.0 4.3e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter PDR_CDR PF06422.12 ORX63782.1 - 3.7e-15 55.6 12.9 1.9e-10 40.5 0.4 3.8 3 1 0 3 3 3 2 CDR ABC transporter AAA_21 PF13304.6 ORX63782.1 - 1.1e-05 25.4 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORX63782.1 - 0.00011 21.4 13.9 0.00011 21.4 13.9 3.4 2 2 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX63782.1 - 0.0008 19.4 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORX63782.1 - 0.0034 17.8 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORX63782.1 - 0.0059 16.3 0.2 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PDR_assoc PF08370.11 ORX63782.1 - 0.0074 16.0 2.0 0.0074 16.0 2.0 4.3 5 0 0 5 5 4 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 ORX63782.1 - 0.0077 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_trans_N PF14510.6 ORX63782.1 - 0.0089 16.6 0.2 0.044 14.4 0.0 2.2 3 0 0 3 3 2 1 ABC-transporter N-terminal SMC_N PF02463.19 ORX63782.1 - 0.044 13.2 0.0 0.42 10.0 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 ORX63782.1 - 0.16 10.5 0.1 2.9 6.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 ORX63782.1 - 0.19 12.2 0.1 0.42 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain PYC_OADA PF02436.18 ORX63782.1 - 0.2 11.4 0.0 0.58 9.9 0.0 1.7 2 0 0 2 2 2 0 Conserved carboxylase domain cobW PF02492.19 ORX63782.1 - 0.24 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane PF01061.24 ORX63783.1 - 6e-09 35.6 5.5 6e-09 35.6 5.5 1.8 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 ORX63783.1 - 2.2e-06 27.5 0.2 3.8e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORX63783.1 - 0.0017 17.5 0.0 0.0024 17.1 0.0 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein tRNA_int_endo PF01974.17 ORX63790.1 - 2.3e-18 66.1 0.1 4.7e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Synaphin PF05835.12 ORX63790.1 - 0.028 14.7 7.4 0.039 14.2 7.4 1.2 1 0 0 1 1 1 0 Synaphin protein Pex14_N PF04695.13 ORX63791.1 - 4.1e-07 30.8 2.6 4.1e-07 30.8 2.6 4.4 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SLATT_6 PF18169.1 ORX63791.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Noggin PF05806.12 ORX63791.1 - 0.12 12.3 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Noggin Snurportin1 PF11538.8 ORX63791.1 - 2.9 8.2 10.4 4 7.7 8.1 2.4 2 0 0 2 2 2 0 Snurportin1 Ald_Xan_dh_C2 PF02738.18 ORX63815.1 - 3.8e-202 672.6 0.1 5.2e-202 672.1 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORX63815.1 - 6.1e-50 169.3 0.0 1.2e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 ORX63815.1 - 1.4e-32 112.3 0.2 3.5e-32 111.0 0.2 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ORX63815.1 - 1.6e-30 105.0 0.0 3.4e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 ORX63815.1 - 2.5e-26 91.8 0.0 8.1e-25 87.0 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 ORX63815.1 - 1.3e-08 34.7 0.2 1.3e-08 34.7 0.2 2.5 3 1 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 ORX63815.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain Cation_ATPase_C PF00689.21 ORX63816.1 - 9.8e-29 100.3 6.9 3.3e-28 98.6 2.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORX63816.1 - 5.2e-22 78.2 1.9 2e-21 76.4 0.3 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORX63816.1 - 2.1e-20 72.6 0.0 3.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX63816.1 - 3.3e-15 56.9 0.0 1.2e-13 51.9 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX63816.1 - 0.00013 21.8 1.7 0.00051 19.9 0.5 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF981 PF06168.11 ORX63816.1 - 0.23 11.3 5.1 10 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF981) Cation_ATPase_N PF00690.26 ORX63817.1 - 2.1e-18 65.7 0.0 2.7e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PRiA4_ORF3 PF07929.11 ORX63818.1 - 2.5e-08 33.8 2.3 1e-07 31.8 2.3 2.1 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Nramp PF01566.18 ORX63827.1 - 3.2e-122 408.0 20.4 3.2e-122 408.0 20.4 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein 7TM_GPCR_Sru PF10322.9 ORX63827.1 - 0.3 10.4 7.0 0.092 12.1 0.9 2.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru GDP_Man_Dehyd PF16363.5 ORX63828.1 - 2.1e-57 195.0 0.0 3.1e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX63828.1 - 2.3e-52 177.9 0.2 3.2e-52 177.4 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX63828.1 - 2.6e-15 56.4 0.0 1.6e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORX63828.1 - 1.6e-14 53.6 0.1 4.2e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORX63828.1 - 8e-11 41.6 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORX63828.1 - 3.5e-08 33.6 0.0 6.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ORX63828.1 - 9.2e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ORX63828.1 - 1.5e-05 25.0 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORX63828.1 - 1.7e-05 24.1 0.1 0.035 13.3 0.1 2.4 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ORX63828.1 - 2.9e-05 23.7 0.2 0.0039 16.8 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family Methyltransf_31 PF13847.6 ORX63828.1 - 0.0087 15.9 0.0 0.17 11.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Semialdhyde_dh PF01118.24 ORX63828.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ORX63828.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 ORX63828.1 - 0.1 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORX63828.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TP_methylase PF00590.20 ORX63829.1 - 4.5e-48 164.0 0.0 8.3e-48 163.1 0.0 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORX63829.1 - 2.3e-22 79.4 0.1 5.7e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORX63829.1 - 2.4e-17 62.3 0.2 8e-17 60.6 0.0 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORX63829.1 - 1.2e-07 31.1 0.3 3.8e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central PPS_PS PF02006.16 ORX63829.1 - 0.016 14.8 0.3 0.093 12.3 0.0 2.3 3 0 0 3 3 3 0 Phosphopantothenate/pantothenate synthetase DUF410 PF04190.13 ORX63830.1 - 1.2e-73 248.1 0.1 1.6e-73 247.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 ORX63830.1 - 0.084 13.0 5.9 28 5.1 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX63830.1 - 0.11 12.5 1.2 17 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX63830.1 - 0.12 12.7 3.9 2.8 8.4 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4851 PF16143.5 ORX63830.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4851) LisH PF08513.11 ORX63835.1 - 2.1e-07 30.7 0.1 2.9e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 LisH adh_short PF00106.25 ORX63836.1 - 2e-23 82.9 0.1 4.3e-23 81.8 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX63836.1 - 6.1e-17 62.0 0.0 1.5e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX63836.1 - 0.00029 20.8 0.6 0.0029 17.6 0.6 2.0 1 1 0 1 1 1 1 KR domain DUF4154 PF13689.6 ORX63836.1 - 0.025 14.8 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 YfiR/HmsC-like CRM1_repeat_2 PF18784.1 ORX63836.1 - 0.12 12.0 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 LisH PF08513.11 ORX63837.1 - 1e-06 28.4 0.2 1.6e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 LisH WD40 PF00400.32 ORX63838.1 - 1.8e-22 79.2 10.8 2.3e-07 31.4 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORX63838.1 - 7.6e-05 21.8 1.6 0.00051 19.1 0.4 2.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX63838.1 - 0.00016 20.5 1.4 0.21 10.2 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORX63838.1 - 0.0068 16.7 0.2 0.28 11.5 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cellulase PF00150.18 ORX63859.1 - 1.3e-07 31.4 0.9 1.8e-07 30.9 0.1 1.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Arrestin_C PF02752.22 ORX63860.1 - 4.9e-15 56.2 0.5 2.3e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX63860.1 - 1.2e-10 41.7 0.0 1.3e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX63860.1 - 0.0015 17.8 0.0 0.53 9.4 0.0 2.8 2 1 0 3 3 3 2 Rgp1 LDB19 PF13002.7 ORX63860.1 - 0.049 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like Arf PF00025.21 ORX63885.1 - 9.1e-80 266.2 0.1 1e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX63885.1 - 1.5e-14 53.8 0.0 1.8e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORX63885.1 - 2.5e-14 53.5 0.0 3.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORX63885.1 - 2.3e-13 50.1 1.1 1.9e-09 37.2 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORX63885.1 - 5.5e-13 48.8 0.0 5.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX63885.1 - 1e-10 41.3 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX63885.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX63885.1 - 0.0073 15.6 0.5 0.018 14.4 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DEAD PF00270.29 ORX63886.1 - 7.8e-47 159.3 0.0 1.2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX63886.1 - 2.4e-24 85.8 0.0 8e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORX63886.1 - 6.1e-22 77.6 1.7 1.5e-21 76.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORX63886.1 - 1.6e-06 28.2 0.0 8.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 ORX63886.1 - 0.016 15.4 0.7 0.039 14.1 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_19 PF13245.6 ORX63886.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SBF_like PF13593.6 ORX63886.1 - 0.21 10.9 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) CIMR PF00878.18 ORX63887.1 - 2.2e-12 47.3 0.6 2.8e-10 40.4 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 ORX63887.1 - 1.9e-11 43.6 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 ORX63887.1 - 1.6e-06 28.2 0.7 0.0062 16.4 0.0 2.7 1 1 1 2 2 2 2 Autophagy-related protein 27 PRKCSH_1 PF13015.6 ORX63887.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Pkinase PF00069.25 ORX63888.1 - 1.7e-61 207.9 0.0 6.1e-61 206.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX63888.1 - 1.2e-26 93.6 0.4 2.8e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX63888.1 - 0.00071 18.6 0.1 0.0014 17.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX63888.1 - 0.0041 16.5 0.5 0.019 14.3 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 ORX63888.1 - 0.0043 17.0 0.1 0.17 11.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX63888.1 - 0.03 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAF-AH_p_II PF03403.13 ORX63888.1 - 0.071 11.6 0.2 0.3 9.5 0.0 2.1 2 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Pkinase_C PF00433.24 ORX63888.1 - 0.12 13.1 0.9 0.36 11.6 0.9 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Serpin PF00079.20 ORX63889.1 - 3.5e-17 62.8 0.0 5.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Oxidored_molyb PF00174.19 ORX63910.1 - 6.7e-54 182.1 0.0 1e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORX63910.1 - 3e-40 137.4 0.2 6.4e-40 136.4 0.2 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 ORX63910.1 - 1.2e-34 118.6 0.0 2.6e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORX63910.1 - 2.1e-29 102.3 0.0 6.4e-29 100.8 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORX63910.1 - 3.8e-21 75.0 0.1 1.3e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORX63910.1 - 4.4e-06 26.9 0.0 1.4e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Zn_Tnp_IS1595 PF12760.7 ORX63918.1 - 0.036 14.0 2.6 0.073 13.1 2.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 ORX63918.1 - 0.12 12.1 5.7 0.062 13.0 3.1 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 ORX63918.1 - 0.41 10.2 3.4 2 8.0 0.0 2.9 4 0 0 4 4 4 0 TFIIB zinc-binding WD40 PF00400.32 ORX63923.1 - 6.1e-17 61.7 20.1 0.001 19.8 0.1 9.3 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX63923.1 - 2e-16 60.1 0.1 0.003 17.8 0.0 7.8 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX63923.1 - 0.00022 20.3 0.0 1.1 8.1 0.0 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORX63923.1 - 0.0032 15.8 0.0 0.0075 14.6 0.0 1.5 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 ORX63923.1 - 0.014 15.4 0.4 43 4.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF2048 PF09752.9 ORX63923.1 - 0.058 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Histone PF00125.24 ORX63924.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX63924.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX63924.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORX63924.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORX63924.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX63924.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX63924.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Aconitase PF00330.20 ORX63926.1 - 1.3e-147 492.5 0.0 1.8e-147 492.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX63926.1 - 1.2e-44 151.8 0.0 2.3e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain p450 PF00067.22 ORX63930.1 - 7.3e-61 206.3 0.0 8e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 ORX63931.1 - 1.1e-18 66.9 0.2 4.2e-07 29.8 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein NUC173 PF08161.12 ORX63932.1 - 2.6e-75 252.6 1.4 2.6e-70 236.2 0.0 4.5 5 0 0 5 5 5 2 NUC173 domain MMS19_C PF12460.8 ORX63932.1 - 0.00029 20.1 1.3 0.00029 20.1 1.3 3.2 3 2 0 3 3 3 1 RNAPII transcription regulator C-terminal MFS_1 PF07690.16 ORX63933.1 - 2.5e-46 158.3 41.8 1.7e-44 152.2 22.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX63933.1 - 1.1e-10 41.0 11.4 1.1e-10 41.0 11.4 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ORX63933.1 - 1.6e-05 24.4 8.1 1.6e-05 24.4 8.1 2.6 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PEPCK_ATP PF01293.20 ORX63941.1 - 1.4e-122 409.7 0.0 1.6e-122 409.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 ORX63941.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 ORX63942.1 - 7.5e-230 763.4 0.0 8.7e-230 763.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORX63943.1 - 7.5e-230 763.4 0.0 8.7e-230 763.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Aa_trans PF01490.18 ORX63944.1 - 1.3e-58 198.6 40.9 1.6e-58 198.3 40.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORX63944.1 - 5e-05 22.3 29.0 5e-05 22.3 29.0 2.5 1 1 1 2 2 2 1 Amino acid permease EBP PF05241.12 ORX63945.1 - 7.1e-56 188.5 6.4 8.5e-56 188.2 6.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein Abhydrolase_3 PF07859.13 ORX63955.1 - 2.1e-55 187.8 0.0 2.7e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX63955.1 - 2.4e-05 23.4 0.2 0.00011 21.3 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ORX63955.1 - 7.7e-05 22.3 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 ORX63955.1 - 0.00013 20.7 0.0 0.0043 15.8 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 ORX63955.1 - 0.0042 16.6 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ORX63955.1 - 0.012 14.6 0.2 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 ORX63955.1 - 0.021 15.4 0.4 0.13 12.9 0.4 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 ORX63955.1 - 0.034 13.8 0.1 9.3 5.8 0.1 2.3 2 0 0 2 2 2 0 Putative esterase Pkinase PF00069.25 ORX63956.1 - 1.2e-65 221.6 0.0 1.3e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX63956.1 - 1.8e-34 119.2 0.0 2.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX63956.1 - 7.3e-07 28.4 0.1 9.5e-07 28.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX63956.1 - 1.5e-05 24.5 0.0 3.1e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX63956.1 - 1.6e-05 24.3 0.2 3e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX63956.1 - 9.1e-05 22.5 0.7 0.011 15.7 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX63956.1 - 0.00034 19.5 0.0 0.00081 18.3 0.0 1.5 1 1 1 2 2 2 1 Fungal protein kinase DUF4135 PF13575.6 ORX63956.1 - 0.011 15.1 0.0 0.021 14.1 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Choline_kinase PF01633.20 ORX63956.1 - 0.11 12.0 1.5 0.2 11.2 1.4 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.16 ORX63964.1 - 4.9e-54 183.6 44.4 4.9e-54 183.6 44.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX63964.1 - 1.5e-15 56.7 25.7 2.1e-15 56.2 25.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX63964.1 - 1.6e-14 53.7 13.0 1.6e-14 53.7 13.0 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter ADH_N PF08240.12 ORX63965.1 - 4.6e-23 81.2 1.9 4.8e-23 81.1 0.2 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX63965.1 - 1.3e-14 54.3 0.0 2.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX63965.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX63965.1 - 6.2e-05 22.4 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ORX63965.1 - 7.8e-05 23.7 0.0 0.00016 22.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase EIF_2_alpha PF07541.12 ORX63965.1 - 0.077 13.1 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit ELFV_dehydrog PF00208.21 ORX63965.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Kazal_1 PF00050.21 ORX63965.1 - 0.12 12.5 2.1 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF3712 PF12505.8 ORX63985.1 - 6.8e-19 68.4 7.1 6e-12 45.9 0.0 4.7 5 0 0 5 5 5 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORX63985.1 - 1.4e-07 31.9 0.3 0.03 14.9 0.0 4.7 4 1 0 4 4 4 2 Late embryogenesis abundant protein Invas_SpaK PF03519.14 ORX63985.1 - 0.088 12.9 0.0 23 5.1 0.0 2.9 3 0 0 3 3 3 0 Invasion protein B family Citrate_synt PF00285.21 ORX63986.1 - 8.5e-106 354.0 0.0 1e-105 353.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CPSF100_C PF13299.6 ORX63998.1 - 0.011 15.9 0.4 0.014 15.6 0.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mucin PF01456.17 ORX63998.1 - 0.077 13.0 41.1 0.13 12.2 41.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Kazal_3 PF18434.1 ORX63998.1 - 0.14 11.9 1.4 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Dicty_REP PF05086.12 ORX63998.1 - 8.5 4.2 17.9 10 3.9 17.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SRAP PF02586.14 ORX63999.1 - 1.1e-51 175.5 0.1 1.9e-51 174.7 0.1 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) CybS PF05328.12 ORX64000.1 - 2e-35 121.4 0.0 2.9e-35 120.9 0.0 1.3 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Acyl_transf_3 PF01757.22 ORX64000.1 - 0.0048 16.0 0.4 0.0064 15.6 0.4 1.1 1 0 0 1 1 1 1 Acyltransferase family RCC1 PF00415.18 ORX64002.1 - 3.4e-26 91.6 12.9 1.1e-07 32.3 0.2 7.2 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORX64002.1 - 4.1e-26 90.2 14.0 3.5e-07 29.8 0.3 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 ORX64002.1 - 1.3e-07 31.4 0.2 3.2e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX64002.1 - 0.00022 21.0 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Hira PF07569.11 ORX64002.1 - 0.027 14.2 1.0 19 4.9 0.0 3.6 3 1 1 4 4 4 0 TUP1-like enhancer of split F-box_4 PF15966.5 ORX64002.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 F-box Elongin_A PF06881.11 ORX64002.1 - 0.21 12.1 0.0 0.37 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Clat_adaptor_s PF01217.20 ORX64003.1 - 7.3e-54 181.6 5.1 9e-54 181.3 5.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_14 PF13428.6 ORX64004.1 - 7.1e-05 23.3 0.1 0.25 12.3 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX64004.1 - 0.00024 21.3 7.6 0.004 17.3 0.1 4.8 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORX64004.1 - 0.00054 20.4 0.4 0.22 12.1 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX64004.1 - 0.0058 16.9 6.0 0.24 11.7 0.5 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat SPOB_a PF14689.6 ORX64004.1 - 0.016 14.9 0.0 0.65 9.8 0.0 2.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_6 PF13174.6 ORX64004.1 - 0.02 15.5 1.3 0.3 11.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX64004.1 - 0.025 14.4 0.4 0.22 11.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX64004.1 - 0.11 12.7 5.0 0.23 11.7 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORX64004.1 - 0.11 13.2 0.2 1.6 9.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORX64004.1 - 0.38 10.8 4.6 0.31 11.1 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CBM_1 PF00734.18 ORX64012.1 - 0.11 12.4 0.7 7.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Fungal cellulose binding domain RRM_1 PF00076.22 ORX64045.1 - 1.5e-19 69.5 0.0 2.1e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX64045.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX64045.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Herpes_BLRF2 PF05812.12 ORX64045.1 - 0.094 12.9 0.8 0.17 12.1 0.8 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein MFS_1 PF07690.16 ORX64054.1 - 1.4e-12 47.3 24.3 1.4e-12 47.3 24.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORX64054.1 - 5e-11 42.6 6.0 1.5e-10 41.0 6.0 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Wzy_C_2 PF11846.8 ORX64054.1 - 0.098 12.6 0.3 0.27 11.1 0.3 1.7 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Sugar_tr PF00083.24 ORX64054.1 - 3.8 6.3 27.3 24 3.6 24.2 2.9 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 ORX64055.1 - 6.5e-14 51.6 15.7 8.5e-14 51.2 15.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX64055.1 - 2.5e-12 46.8 9.0 2.5e-12 46.8 9.0 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORX64055.1 - 0.002 17.2 4.6 0.0031 16.6 4.6 1.4 1 0 0 1 1 1 1 PUCC protein CPP1-like PF11833.8 ORX64055.1 - 0.058 13.1 2.8 0.12 12.0 2.6 1.8 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PRMT5 PF05185.16 ORX64056.1 - 2.2e-68 229.5 0.0 3.5e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 ORX64056.1 - 1.8e-57 194.5 1.2 3e-57 193.7 1.2 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 ORX64056.1 - 6.4e-54 182.5 1.6 1.1e-53 181.8 1.6 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain USP8_dimer PF08969.11 ORX64056.1 - 0.054 13.7 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 USP8 dimerisation domain TarH PF02203.15 ORX64056.1 - 0.14 12.1 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue eIF2_C PF09173.11 ORX64057.1 - 2.1e-36 124.0 0.2 5.3e-36 122.7 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORX64057.1 - 4.1e-23 81.9 1.0 3.9e-22 78.7 1.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORX64057.1 - 7.7e-12 45.4 0.7 7.7e-12 45.4 0.7 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ORX64057.1 - 0.0012 18.8 0.3 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORX64057.1 - 0.0025 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORX64057.1 - 0.0037 17.3 0.1 0.0083 16.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 ORX64057.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Ribosomal_S17_N PF16205.5 ORX64058.1 - 1.6e-33 114.9 0.5 3.4e-33 113.8 0.5 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORX64058.1 - 2.3e-27 94.9 0.4 3.7e-27 94.2 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L29 PF00831.23 ORX64059.1 - 2.2e-21 75.6 3.2 2.2e-21 75.6 3.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 ORX64059.1 - 0.14 12.6 9.9 0.073 13.5 2.3 2.1 1 1 1 2 2 2 0 Snapin/Pallidin MRP-L47 PF06984.13 ORX64059.1 - 0.29 11.3 4.2 0.24 11.6 1.5 2.2 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Prefoldin PF02996.17 ORX64059.1 - 1.1 9.2 10.0 4.1 7.4 2.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit Snf7 PF03357.21 ORX64059.1 - 3.2 7.3 12.0 2.6 7.6 1.0 2.1 1 1 1 2 2 2 0 Snf7 DUF974 PF06159.13 ORX64060.1 - 0.00047 20.0 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 ORX64060.1 - 0.0016 17.9 0.1 0.023 14.1 0.0 1.9 1 1 1 2 2 2 1 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 ORX64060.1 - 0.044 13.9 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Ldh_1_N PF00056.23 ORX64068.1 - 4e-29 101.5 0.5 7.8e-29 100.6 0.5 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX64068.1 - 1.2e-22 80.7 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORX64069.1 - 1.3e-36 125.8 1.6 2.5e-36 124.9 1.6 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX64069.1 - 1.3e-22 80.5 0.0 2.4e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX64069.1 - 0.0016 18.1 1.4 0.017 14.7 0.6 2.5 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORX64069.1 - 0.019 15.6 1.3 0.1 13.2 0.5 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX64069.1 - 0.027 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX64069.1 - 0.041 14.2 0.3 0.068 13.4 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 ORX64069.1 - 0.071 13.0 0.2 0.071 13.0 0.2 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORX64069.1 - 0.082 12.5 1.1 0.19 11.3 1.1 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 ORX64069.1 - 0.099 12.2 0.6 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 ORX64069.1 - 4.5 6.8 5.1 29 4.1 3.3 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase CBM9_1 PF06452.11 ORX64070.1 - 1.5e-11 44.6 0.1 3.1e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like AAA_2 PF07724.14 ORX64071.1 - 2.9e-52 177.2 0.0 7.7e-50 169.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORX64071.1 - 4.3e-36 123.0 2.2 4.3e-36 123.0 2.2 2.8 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 ORX64071.1 - 6.8e-29 101.0 0.6 7.1e-15 55.6 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORX64071.1 - 6.8e-21 74.1 2.4 1.9e-20 72.7 0.4 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORX64071.1 - 2.2e-19 69.8 0.6 4.3e-12 46.2 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX64071.1 - 4.2e-13 50.0 11.6 6e-07 30.0 0.0 5.2 3 3 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 ORX64071.1 - 3.2e-10 40.4 0.6 0.0022 18.3 0.0 4.3 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 ORX64071.1 - 7.9e-09 35.4 0.0 4.2e-05 23.3 0.0 3.0 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORX64071.1 - 1e-07 31.6 0.0 0.00067 19.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORX64071.1 - 1.8e-07 31.1 0.0 0.027 14.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 ORX64071.1 - 3.2e-07 30.5 3.1 0.31 10.9 0.1 4.5 3 2 1 5 5 5 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORX64071.1 - 8.8e-07 29.0 0.3 0.11 12.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 ORX64071.1 - 8.9e-07 28.5 2.2 0.11 11.9 0.0 4.5 3 1 1 4 4 4 1 Bacterial TniB protein RuvB_N PF05496.12 ORX64071.1 - 1e-05 25.4 5.4 0.061 13.1 0.0 4.9 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORX64071.1 - 2.6e-05 24.8 2.0 0.14 12.7 0.0 4.0 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 ORX64071.1 - 3.1e-05 24.0 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 ORX64071.1 - 3.9e-05 24.0 0.1 0.15 12.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 ORX64071.1 - 8.3e-05 22.8 0.0 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 ORX64071.1 - 0.00013 21.8 0.1 0.091 12.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ORX64071.1 - 0.00016 21.9 0.0 0.35 11.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORX64071.1 - 0.0002 21.6 3.7 2.9 8.1 0.0 4.4 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORX64071.1 - 0.00047 20.1 0.1 0.85 9.5 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase Zeta_toxin PF06414.12 ORX64071.1 - 0.00056 19.2 0.5 0.14 11.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 ORX64071.1 - 0.00057 19.3 0.1 0.8 9.0 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORX64071.1 - 0.0008 19.4 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ORX64071.1 - 0.00087 18.9 5.3 0.081 12.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain DNA_pol3_delta2 PF13177.6 ORX64071.1 - 0.0014 18.4 0.0 0.37 10.6 0.0 3.3 4 0 0 4 4 3 1 DNA polymerase III, delta subunit AAA_8 PF12780.7 ORX64071.1 - 0.0025 17.2 0.0 0.59 9.4 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 DUF815 PF05673.13 ORX64071.1 - 0.0027 16.9 0.1 1.4 8.0 0.0 3.2 3 1 0 3 3 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 ORX64071.1 - 0.0029 17.6 0.0 0.55 10.2 0.0 3.3 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX64071.1 - 0.0044 17.4 0.3 0.18 12.1 0.1 3.1 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORX64071.1 - 0.0046 16.7 0.0 5.9 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain EzrA PF06160.12 ORX64071.1 - 0.0048 15.1 11.5 0.0081 14.4 11.5 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SRP54 PF00448.22 ORX64071.1 - 0.0062 16.2 0.0 2.9 7.5 0.0 2.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORX64071.1 - 0.0073 16.0 0.0 3.9 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX64071.1 - 0.0089 16.0 0.1 3.2 7.6 0.0 3.2 3 0 0 3 3 3 1 NTPase PhoH PF02562.16 ORX64071.1 - 0.011 15.3 0.0 0.95 8.9 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 ORX64071.1 - 0.015 15.8 0.9 1.5 9.3 0.0 3.3 3 0 0 3 3 3 0 ABC transporter DUF87 PF01935.17 ORX64071.1 - 0.024 14.7 5.1 0.36 10.9 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain DnaB_C PF03796.15 ORX64071.1 - 0.044 13.1 0.4 2 7.7 0.0 2.8 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain AAA_29 PF13555.6 ORX64071.1 - 0.061 13.1 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 ORX64071.1 - 0.064 12.2 0.0 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Ras PF00071.22 ORX64071.1 - 0.14 11.7 0.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 Ras family BLOC1_2 PF10046.9 ORX64071.1 - 0.92 9.9 9.5 0.44 10.9 5.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cob_adeno_trans PF01923.18 ORX64071.1 - 1 9.5 4.0 1.1 9.4 1.9 2.2 2 0 0 2 2 1 0 Cobalamin adenosyltransferase AAA_23 PF13476.6 ORX64071.1 - 1.4 9.4 0.0 1.4 9.4 0.0 4.0 3 1 0 3 3 2 0 AAA domain V_ATPase_I PF01496.19 ORX64071.1 - 2.3 6.0 3.3 3 5.6 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.13 ORX64071.1 - 9.7 6.1 7.7 2.7 7.9 3.1 2.2 1 1 1 2 2 2 0 Aphid transmission protein AAA_2 PF07724.14 ORX64072.1 - 3.5e-52 177.0 0.1 1.1e-49 168.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORX64072.1 - 5.8e-36 122.6 2.2 5.8e-36 122.6 2.2 3.1 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 ORX64072.1 - 1.2e-28 100.2 0.6 9.9e-15 55.1 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORX64072.1 - 2.2e-20 72.5 0.3 2.2e-20 72.5 0.3 3.1 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORX64072.1 - 4.3e-19 68.9 0.4 5.9e-12 45.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 ORX64072.1 - 1.7e-13 50.4 1.8 1.4e-05 25.1 0.8 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 ORX64072.1 - 5.5e-12 46.4 14.0 7.9e-07 29.6 0.0 5.4 4 3 1 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 ORX64072.1 - 1e-09 38.8 1.5 0.003 17.8 0.0 4.6 4 1 0 4 4 2 2 AAA domain Sigma54_activat PF00158.26 ORX64072.1 - 1.5e-08 34.5 0.0 5.9e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORX64072.1 - 1.7e-07 30.9 0.0 0.00088 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORX64072.1 - 3.1e-07 30.3 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 ORX64072.1 - 6.1e-07 29.6 2.7 0.38 10.6 0.1 4.4 3 2 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORX64072.1 - 2e-06 27.9 0.3 0.15 12.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 ORX64072.1 - 2.2e-06 27.2 2.2 0.15 11.5 0.0 4.6 3 1 1 4 4 4 1 Bacterial TniB protein RuvB_N PF05496.12 ORX64072.1 - 2.2e-05 24.2 5.7 0.08 12.7 0.0 5.1 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORX64072.1 - 3e-05 24.2 0.0 0.16 12.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ORX64072.1 - 4.2e-05 24.1 1.8 0.2 12.2 0.0 4.0 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 ORX64072.1 - 4.2e-05 23.5 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 ORX64072.1 - 5.5e-05 23.5 0.0 0.2 12.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.11 ORX64072.1 - 0.00023 21.0 0.1 0.12 12.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ORX64072.1 - 0.00026 21.2 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORX64072.1 - 0.0004 20.7 3.3 3.7 7.8 0.0 4.4 3 1 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 ORX64072.1 - 0.00062 19.7 0.3 1.1 9.1 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase Zeta_toxin PF06414.12 ORX64072.1 - 0.001 18.4 1.5 0.18 11.0 0.0 3.8 4 0 0 4 4 4 1 Zeta toxin Mg_chelatase PF01078.21 ORX64072.1 - 0.0012 18.2 0.1 1.1 8.6 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORX64072.1 - 0.0013 18.7 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 ORX64072.1 - 0.0028 17.5 0.1 0.11 12.2 0.0 3.2 2 1 0 2 2 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.6 ORX64072.1 - 0.0041 16.7 6.8 0.11 12.1 0.0 3.9 5 0 0 5 5 3 1 AAA domain ResIII PF04851.15 ORX64072.1 - 0.0054 16.8 0.0 0.73 9.8 0.0 3.3 2 1 0 3 3 2 1 Type III restriction enzyme, res subunit EzrA PF06160.12 ORX64072.1 - 0.0058 14.9 11.5 0.011 14.0 11.5 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_30 PF13604.6 ORX64072.1 - 0.007 16.1 0.0 7.6 6.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX64072.1 - 0.0074 16.6 0.3 0.28 11.5 0.1 3.1 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.22 ORX64072.1 - 0.0088 15.7 0.0 3.7 7.1 0.0 3.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORX64072.1 - 0.011 15.5 0.0 5.2 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX64072.1 - 0.016 15.1 0.1 4.1 7.3 0.0 3.2 3 0 0 3 3 2 0 NTPase PhoH PF02562.16 ORX64072.1 - 0.018 14.5 0.0 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein DUF87 PF01935.17 ORX64072.1 - 0.028 14.5 4.8 0.47 10.5 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 ORX64072.1 - 0.029 14.9 1.1 2.1 8.9 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_6 PF12774.7 ORX64072.1 - 0.062 12.3 0.1 0.57 9.1 0.0 2.4 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 ORX64072.1 - 0.1 12.4 0.0 21 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX64072.1 - 2 8.9 0.0 2 8.9 0.0 4.3 4 1 0 4 4 2 0 AAA domain BLOC1_2 PF10046.9 ORX64072.1 - 3.1 8.1 10.7 0.54 10.6 5.0 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C2H2 PF00096.26 ORX64097.1 - 3.5e-11 42.9 17.4 2.5e-06 27.7 1.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX64097.1 - 3.2e-09 36.8 14.5 1.7e-08 34.5 0.8 3.4 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX64097.1 - 4.6e-08 33.2 13.7 0.00048 20.7 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX64097.1 - 9.7e-06 25.7 5.2 0.017 15.4 0.5 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX64097.1 - 0.00027 21.2 3.8 0.00077 19.7 3.9 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORX64097.1 - 0.0008 19.3 3.1 0.054 13.5 0.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORX64097.1 - 0.0025 18.1 1.7 1.1 9.6 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 ORX64097.1 - 0.0067 16.3 6.8 0.93 9.5 3.5 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.7 ORX64097.1 - 0.0069 16.8 3.3 0.0077 16.6 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.9 ORX64097.1 - 0.045 13.5 0.2 4.2 7.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 ORX64097.1 - 0.083 12.7 0.2 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF3449 PF11931.8 ORX64097.1 - 0.093 12.5 0.8 0.096 12.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) GAGA PF09237.11 ORX64097.1 - 0.12 12.2 6.9 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 GAGA factor UBZ_FAAP20 PF15750.5 ORX64097.1 - 0.15 12.0 0.3 21 5.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DUF629 PF04780.12 ORX64097.1 - 0.17 10.4 1.2 0.17 10.4 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf_ZIC PF18366.1 ORX64097.1 - 0.19 11.9 3.2 1.4 9.1 0.5 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain Zf_RING PF16744.5 ORX64097.1 - 0.19 11.9 1.2 0.17 12.1 0.3 1.5 1 1 1 2 2 2 0 KIAA1045 RING finger zf-met2 PF12907.7 ORX64097.1 - 0.21 11.8 0.2 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 Zinc-binding zf-MYST PF17772.1 ORX64097.1 - 0.36 10.5 5.8 2.6 7.7 0.5 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain DUF2256 PF10013.9 ORX64097.1 - 0.4 10.8 2.7 1.8 8.7 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH PF01844.23 ORX64097.1 - 0.59 10.4 5.8 2 8.6 0.9 2.1 2 0 0 2 2 2 0 HNH endonuclease zf-MYND PF01753.18 ORX64097.1 - 2.6 8.2 7.5 33 4.7 7.5 2.1 1 1 0 1 1 1 0 MYND finger Iron_permease PF04120.12 ORX64098.1 - 6.4e-40 135.9 18.5 9.4e-17 61.0 0.5 4.1 4 0 0 4 4 4 4 Low affinity iron permease Glyco_hydro_61 PF03443.14 ORX64103.1 - 0.0015 18.5 0.1 0.11 12.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX64103.1 - 0.0024 18.5 1.4 0.012 16.2 1.4 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GPI-anchored PF10342.9 ORX64103.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family COQ9 PF08511.11 ORX64104.1 - 1.1e-32 111.6 0.7 1.5e-32 111.1 0.7 1.2 1 0 0 1 1 1 1 COQ9 Sel1 PF08238.12 ORX64131.1 - 6e-21 74.4 7.1 7.9e-07 29.6 1.1 4.1 4 0 0 4 4 4 4 Sel1 repeat FH2 PF02181.23 ORX64132.1 - 1.5e-96 323.8 2.4 1.5e-96 323.8 2.4 3.1 2 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORX64132.1 - 2.7e-28 98.8 5.5 2.7e-28 98.8 5.5 3.1 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORX64132.1 - 1.5e-26 93.2 0.3 1.5e-26 93.2 0.3 3.0 2 1 1 3 3 3 1 Diaphanous FH3 Domain RA PF00788.23 ORX64132.1 - 3.2e-06 27.7 0.0 0.00061 20.4 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 ORX64132.1 - 0.041 14.2 1.0 0.75 10.2 0.0 3.4 4 0 0 4 4 4 0 Ras-binding domain of Byr2 TMF_TATA_bd PF12325.8 ORX64132.1 - 2.9 8.2 32.7 0.43 10.8 0.2 5.9 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 ORX64132.1 - 2.9 8.2 14.0 7.1 6.9 0.6 5.3 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain RPW8 PF05659.11 ORX64132.1 - 5.8 6.6 7.9 3.9 7.2 0.6 3.7 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tup_N PF08581.10 ORX64132.1 - 9.1 6.7 9.1 1 9.7 0.5 3.6 3 0 0 3 3 3 0 Tup N-terminal Peroxidase_2 PF01328.17 ORX64133.1 - 9.2e-53 179.6 0.0 1.3e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 RWD PF05773.22 ORX64149.1 - 5.8e-15 55.6 7.2 6.8e-15 55.4 7.2 1.1 1 0 0 1 1 1 1 RWD domain Aldo_ket_red PF00248.21 ORX64150.1 - 2.7e-49 168.0 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CPL PF08144.11 ORX64151.1 - 7.1e-44 149.6 6.4 1.7e-39 135.4 0.0 5.0 5 1 0 5 5 5 2 CPL (NUC119) domain PUF PF00806.19 ORX64151.1 - 0.011 15.4 0.4 4.5 7.2 0.0 4.5 5 0 0 5 5 5 0 Pumilio-family RNA binding repeat DUF732 PF05305.14 ORX64151.1 - 0.055 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF3683 PF12447.8 ORX64151.1 - 0.072 13.2 0.2 4.9 7.3 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3683) DUF572 PF04502.13 ORX64151.1 - 0.099 12.3 5.3 0.19 11.3 5.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L11 PF00298.19 ORX64152.1 - 6.3e-29 100.3 0.1 1.1e-28 99.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 ORX64152.1 - 3.2e-28 97.4 0.5 4.9e-28 96.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Rep_fac-A_C PF08646.10 ORX64153.1 - 2.3e-55 186.4 3.2 4.6e-53 178.9 0.6 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 ORX64153.1 - 1.9e-39 133.5 1.0 6.7e-38 128.6 0.4 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 ORX64153.1 - 1.3e-30 105.3 0.5 3.7e-30 103.9 0.5 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 ORX64153.1 - 2.1e-12 46.8 0.4 5.1e-10 39.2 0.0 3.8 4 1 0 4 4 4 1 OB-fold nucleic acid binding domain BRCA-2_OB1 PF09103.10 ORX64153.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 POT1 PF02765.17 ORX64153.1 - 0.0034 17.2 1.6 0.015 15.2 0.0 2.6 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 ORX64153.1 - 0.0035 17.1 0.3 0.036 13.8 0.0 2.6 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DHHC PF01529.20 ORX64154.1 - 1.2e-26 93.4 14.3 1.4e-26 93.2 14.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase PSI PF01437.25 ORX64154.1 - 0.0029 18.1 7.0 0.0029 18.1 7.0 1.6 2 0 0 2 2 2 1 Plexin repeat Imm17 PF15562.6 ORX64154.1 - 0.0033 17.3 0.1 0.0062 16.4 0.1 1.4 1 0 0 1 1 1 1 Immunity protein 17 RIO1 PF01163.22 ORX64156.1 - 2.9e-78 261.8 0.4 4.7e-78 261.1 0.4 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORX64156.1 - 0.00012 22.1 0.0 0.3 11.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORX64156.1 - 0.0042 16.5 0.5 0.37 10.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.12 ORX64156.1 - 0.028 13.5 0.4 0.069 12.2 0.3 1.6 1 1 1 2 2 2 0 Autophagy protein Apg17 Pkinase_fungal PF17667.1 ORX64156.1 - 0.037 12.8 0.1 0.061 12.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Myticin-prepro PF10690.9 ORX64167.1 - 0.0014 18.9 0.3 0.0021 18.2 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel adh_short PF00106.25 ORX64168.1 - 1.5e-30 106.1 0.0 7.5e-23 81.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX64168.1 - 1e-21 77.6 0.0 1.8e-20 73.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX64168.1 - 1.4e-09 38.1 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX64168.1 - 0.0017 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORX64168.1 - 0.011 15.8 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORX64168.1 - 0.032 14.7 0.1 0.076 13.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding PA PF02225.22 ORX64168.1 - 0.046 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 PA domain IlvN PF07991.12 ORX64181.1 - 3.8e-45 153.4 0.0 6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORX64181.1 - 9.1e-21 74.6 0.3 1.1e-10 41.9 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 ORX64181.1 - 0.00021 21.5 0.0 0.00055 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORX64181.1 - 0.066 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORX64181.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 ORX64182.1 - 3.2e-45 153.6 0.0 5.1e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORX64182.1 - 1.7e-42 145.1 0.2 2.7e-42 144.4 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 ORX64182.1 - 0.0002 21.5 0.0 0.00048 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORX64182.1 - 0.06 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORX64182.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Chs7 PF12271.8 ORX64183.1 - 1.3e-91 306.9 15.9 1.5e-91 306.7 15.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Guanylate_kin PF00625.21 ORX64184.1 - 8.4e-67 224.4 0.0 9.6e-67 224.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ORX64184.1 - 2.2e-08 34.7 0.2 5.8e-08 33.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORX64184.1 - 7.4e-06 26.2 0.0 0.0001 22.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX64184.1 - 0.00017 21.9 0.0 0.00056 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX64184.1 - 0.00019 22.0 0.0 0.0005 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORX64184.1 - 0.00029 20.0 0.0 0.00056 19.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORX64184.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 ORX64184.1 - 0.0018 18.2 0.0 0.0092 15.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 ORX64184.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORX64184.1 - 0.0039 17.7 0.0 0.0069 16.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 ORX64184.1 - 0.0053 16.1 0.0 0.024 13.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 ORX64184.1 - 0.0065 16.4 0.1 0.012 15.5 0.1 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORX64184.1 - 0.0084 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 ORX64184.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX64184.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORX64184.1 - 0.016 14.5 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 ORX64184.1 - 0.016 15.4 0.1 0.042 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 ORX64184.1 - 0.019 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 ORX64184.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 ORX64184.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_17 PF13207.6 ORX64184.1 - 0.04 14.3 0.3 0.28 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 ORX64184.1 - 0.048 13.5 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 ORX64184.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 ORX64184.1 - 0.054 12.7 0.0 0.096 11.9 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 ORX64184.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORX64184.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Orthopox_A43R PF06517.11 ORX64184.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 2 0 0 2 2 1 0 Orthopoxvirus A43R protein CbiA PF01656.23 ORX64184.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 ORX64184.1 - 0.11 12.1 0.1 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORX64184.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain WGG PF10273.9 ORX64185.1 - 3.8e-28 98.0 0.8 3.8e-28 98.0 0.8 1.4 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 rOmpB PF12334.8 ORX64185.1 - 0.052 13.0 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Lyase_8_N PF08124.11 ORX64186.1 - 0.043 12.7 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain MIP PF00230.20 ORX64203.1 - 5.2e-53 180.1 10.7 6.5e-53 179.8 10.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein nlz1 PF12402.8 ORX64203.1 - 0.08 13.4 0.4 0.23 11.9 0.4 1.7 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 LysM PF01476.20 ORX64232.1 - 3.1e-07 30.3 0.0 5.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain IER PF05760.12 ORX64232.1 - 0.064 13.5 0.5 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 Immediate early response protein (IER) RGS PF00615.19 ORX64233.1 - 1.7e-12 47.6 0.6 2.7e-12 47.0 0.6 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mito_carr PF00153.27 ORX64243.1 - 8.3e-29 99.4 2.2 2.4e-13 49.8 0.0 3.1 3 1 0 3 3 3 2 Mitochondrial carrier protein zf-FPG_IleRS PF06827.14 ORX64243.1 - 0.046 13.6 0.2 0.097 12.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS YtxH PF12732.7 ORX64243.1 - 0.09 13.3 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 YtxH-like protein CBM_19 PF03427.13 ORX64272.1 - 3.5e-12 46.1 35.9 0.00075 19.4 2.9 5.2 4 1 1 5 5 5 5 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX64272.1 - 1.6e-06 28.2 39.9 0.12 12.5 4.5 5.3 3 1 1 4 4 4 4 Chitin binding Peritrophin-A domain DUF1376 PF07120.11 ORX64272.1 - 0.0072 16.6 0.3 11 6.4 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1376) SCNM1_acidic PF15805.5 ORX64272.1 - 0.11 12.3 4.2 31 4.4 0.0 3.8 4 0 0 4 4 4 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DUF2793 PF10983.8 ORX64272.1 - 0.18 11.7 0.1 5 7.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2793) Kazal_3 PF18434.1 ORX64272.1 - 0.51 10.1 19.0 3 7.7 0.1 4.9 4 0 0 4 4 4 0 Kazal-type serine protease inhibitor domain Acetyltransf_5 PF13444.6 ORX64302.1 - 8.7e-08 32.8 0.0 1.3e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX64302.1 - 6.2e-05 22.9 0.0 0.00084 19.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX64302.1 - 6.5e-05 23.1 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORX64302.1 - 0.0001 22.4 0.0 0.0097 16.0 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.26 ORX64315.1 - 1e-10 41.4 13.0 1.4e-05 25.2 2.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX64315.1 - 8e-09 35.6 10.5 0.00051 20.6 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX64315.1 - 5.6e-07 29.7 15.0 2.4e-06 27.7 4.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORX64315.1 - 1.2e-06 28.7 5.3 0.0014 19.0 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX64315.1 - 3.2e-06 27.3 4.5 0.016 15.5 2.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORX64315.1 - 0.028 14.7 2.6 1.2 9.5 0.5 2.6 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 ORX64315.1 - 0.041 14.5 1.5 0.26 11.9 0.2 2.5 3 0 0 3 3 3 0 FOXP coiled-coil domain Acyltransf_C PF16076.5 ORX64315.1 - 0.12 12.5 0.3 0.27 11.4 0.3 1.7 1 1 0 1 1 1 0 Acyltransferase C-terminus zf-BED PF02892.15 ORX64315.1 - 0.15 12.1 6.8 6.9 6.8 1.5 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 ORX64315.1 - 0.21 11.6 4.9 0.4 10.8 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX64316.1 - 1.1e-09 38.1 12.7 0.00016 22.0 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX64316.1 - 1.3e-09 38.0 10.8 3.8e-06 27.1 4.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX64316.1 - 2.5e-08 34.1 10.6 0.0003 21.4 1.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX64316.1 - 8.7e-05 22.7 8.5 0.033 14.5 1.3 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX64316.1 - 0.00015 22.0 1.8 0.088 13.1 0.6 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORX64316.1 - 0.00033 21.0 8.9 0.0029 17.9 0.7 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORX64316.1 - 0.00096 19.7 3.8 0.0039 17.8 0.3 2.2 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 ORX64316.1 - 0.021 15.5 1.2 0.22 12.2 1.5 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met2 PF12907.7 ORX64316.1 - 0.036 14.2 2.1 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 Zinc-binding DUF4692 PF15763.5 ORX64316.1 - 0.062 13.8 0.0 0.089 13.3 0.0 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) zf_ZIC PF18366.1 ORX64316.1 - 0.32 11.1 2.5 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-BED PF02892.15 ORX64316.1 - 1.1 9.4 6.5 5.3 7.1 2.6 2.6 1 1 1 2 2 2 0 BED zinc finger DnaJ PF00226.31 ORX64332.1 - 2.6e-24 85.1 2.5 4.4e-24 84.4 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 ORX64332.1 - 1.7e-21 77.1 36.7 1.4e-16 61.0 21.0 2.2 2 1 1 3 3 3 2 Transmembrane Fragile-X-F protein Phage_holin_3_6 PF07332.11 ORX64332.1 - 2.9 8.0 26.0 0.14 12.2 0.3 4.0 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III RAMP4 PF06624.12 ORX64332.1 - 6.3 6.9 6.0 0.82 9.8 0.4 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF3472 PF11958.8 ORX64343.1 - 4.6e-06 27.2 0.3 9.8e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) PQQ_2 PF13360.6 ORX64360.1 - 1.2e-07 31.6 2.1 8.3e-07 28.8 2.2 2.4 1 1 0 1 1 1 1 PQQ-like domain Baculo_Y142 PF04913.12 ORX64360.1 - 0.15 10.7 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus Y142 protein PEX11 PF05648.14 ORX64361.1 - 1.6e-56 191.3 6.2 1.8e-56 191.1 6.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SieB PF14163.6 ORX64361.1 - 0.19 11.2 2.7 0.45 10.0 2.5 1.7 1 1 0 1 1 1 0 Super-infection exclusion protein B Med4 PF10018.9 ORX64361.1 - 0.48 10.1 2.6 0.8 9.4 1.9 1.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 G6PD_C PF02781.16 ORX64362.1 - 4.2e-116 387.2 0.0 1.4e-115 385.5 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORX64362.1 - 5.2e-59 199.8 0.1 8.1e-59 199.2 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3291 PF11695.8 ORX64380.1 - 2e-57 192.8 0.2 2.3e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) DUF3291 PF11695.8 ORX64381.1 - 2e-57 192.8 0.2 2.3e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) COX_ARM PF06481.14 ORX64382.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 COX Aromatic Rich Motif 4F5 PF04419.14 ORX64399.1 - 2e-06 28.5 8.7 3.2e-06 27.9 8.7 1.4 1 0 0 1 1 1 1 4F5 protein family Sel_put PF04328.13 ORX64399.1 - 0.0032 17.5 0.1 0.0067 16.4 0.1 1.4 1 0 0 1 1 1 1 Selenoprotein, putative zf-C2H2_4 PF13894.6 ORX64399.1 - 0.029 15.2 0.5 0.046 14.6 0.5 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met2 PF12907.7 ORX64399.1 - 0.033 14.3 4.7 0.11 12.6 4.7 1.8 1 1 0 1 1 1 0 Zinc-binding zf-C2H2_2 PF12756.7 ORX64399.1 - 0.072 13.4 0.1 0.072 13.4 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prothymosin PF03247.14 ORX64403.1 - 0.051 14.0 17.9 0.067 13.7 17.9 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.12 ORX64403.1 - 1.4 8.2 12.2 1.5 8.0 12.2 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 ORX64403.1 - 1.8 8.6 6.7 2.2 8.3 6.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Gpi16 PF04113.14 ORX64404.1 - 3.6e-175 583.6 0.1 7e-174 579.4 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Homeodomain PF00046.29 ORX64404.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain RNA_pol_Rpb4 PF03874.16 ORX64406.1 - 3e-20 72.8 0.3 3.4e-20 72.6 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Orbi_NS1 PF01718.16 ORX64406.1 - 0.067 11.6 0.0 0.074 11.5 0.0 1.0 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Yae1_N PF09811.9 ORX64413.1 - 0.027 14.2 0.5 0.12 12.1 0.1 2.1 2 1 0 2 2 2 0 Essential protein Yae1, N terminal LRR_4 PF12799.7 ORX64414.1 - 0.00054 20.3 12.6 0.036 14.5 1.7 5.0 3 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX64414.1 - 0.0025 18.1 5.5 28 5.8 0.1 5.7 4 1 0 4 4 4 1 Leucine Rich Repeat Importin_rep PF18773.1 ORX64414.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat LRR_6 PF13516.6 ORX64414.1 - 0.15 12.1 9.0 3 8.1 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat zf-C2HC5 PF06221.13 ORX64415.1 - 3.7e-17 62.1 7.3 5.9e-17 61.4 7.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Med1 PF10744.9 ORX64416.1 - 6.5e-10 38.6 1.4 8.4e-08 31.7 0.1 2.3 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 DJ-1_PfpI PF01965.24 ORX64426.1 - 4.6e-05 23.3 0.0 0.00041 20.2 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX64426.1 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX64426.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain Pyr_redox_2 PF07992.14 ORX64446.1 - 1.2e-59 202.0 0.1 1.7e-59 201.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX64446.1 - 1.5e-14 54.3 0.1 1.5e-14 54.3 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX64446.1 - 1.9e-14 53.9 1.2 1.2e-12 48.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 ORX64446.1 - 2.9e-12 47.0 0.0 1.1e-11 45.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 ORX64446.1 - 6.4e-11 42.0 0.5 1.1e-09 38.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX64446.1 - 1e-06 28.8 3.4 0.031 14.5 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX64446.1 - 0.00022 21.2 1.6 0.97 9.4 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX64446.1 - 0.00063 18.9 3.0 0.071 12.2 0.4 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 ORX64446.1 - 0.0034 16.7 0.0 0.091 12.0 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORX64446.1 - 0.014 14.5 5.3 0.91 8.5 0.3 3.1 3 0 0 3 3 3 0 FAD binding domain K_oxygenase PF13434.6 ORX64446.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 ORX64446.1 - 0.023 14.2 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) HI0933_like PF03486.14 ORX64446.1 - 0.03 13.0 6.1 1.4 7.5 1.0 3.2 2 1 1 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 ORX64446.1 - 0.031 14.2 0.7 0.056 13.3 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RELT PF12606.8 ORX64446.1 - 0.034 13.1 0.1 0.062 12.3 0.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DAO PF01266.24 ORX64446.1 - 0.071 12.7 6.7 0.65 9.5 0.2 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORX64446.1 - 0.08 12.2 0.9 0.21 10.8 0.7 1.7 1 1 0 1 1 1 0 FAD binding domain ThiF PF00899.21 ORX64446.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 ORX64446.1 - 4.9 6.4 6.2 1.7 7.9 1.6 2.6 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain PLA2G12 PF06951.11 ORX64456.1 - 1.2e-07 31.8 8.3 1.8e-07 31.3 8.3 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Mo25 PF08569.11 ORX64457.1 - 4.2e-121 404.3 1.1 4.7e-121 404.1 1.1 1.0 1 0 0 1 1 1 1 Mo25-like DUF1150 PF06620.11 ORX64496.1 - 0.027 14.6 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) DUF3291 PF11695.8 ORX64497.1 - 4.6e-56 188.3 0.2 5.2e-56 188.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) DUF3291 PF11695.8 ORX64498.1 - 2.9e-41 140.4 0.2 1.3e-30 105.9 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3291) Arrestin_C PF02752.22 ORX64509.1 - 7.8e-11 42.6 0.2 1.1e-06 29.1 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX64509.1 - 6.3e-07 29.5 0.0 1.7e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4413 PF14372.6 ORX64509.1 - 0.12 12.7 0.1 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) AAA PF00004.29 ORX64510.1 - 1.4e-43 148.5 0.0 2.4e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORX64510.1 - 7.9e-25 86.6 0.0 3.5e-24 84.6 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORX64510.1 - 2.8e-24 84.9 5.3 6.4e-24 83.8 5.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORX64510.1 - 2.4e-08 33.7 0.0 6.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORX64510.1 - 6.8e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORX64510.1 - 1.6e-05 25.3 0.0 0.0018 18.7 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORX64510.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORX64510.1 - 4.8e-05 22.7 0.0 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 ORX64510.1 - 5.6e-05 23.2 0.0 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX64510.1 - 7e-05 23.1 0.1 0.0066 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORX64510.1 - 7e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORX64510.1 - 0.00037 20.9 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 ORX64510.1 - 0.00038 19.7 0.0 0.0007 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORX64510.1 - 0.00052 20.6 0.2 0.0019 18.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 ORX64510.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORX64510.1 - 0.0013 18.9 0.1 0.0052 16.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 ORX64510.1 - 0.0027 17.5 0.3 0.0099 15.6 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 ORX64510.1 - 0.0093 16.4 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORX64510.1 - 0.025 14.1 0.1 0.72 9.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 ORX64510.1 - 0.03 13.8 0.0 0.094 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 ORX64510.1 - 0.038 13.8 0.0 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 ORX64510.1 - 0.04 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORX64510.1 - 0.045 13.7 0.0 0.73 9.7 0.0 2.4 1 1 1 2 2 2 0 NACHT domain USP8_dimer PF08969.11 ORX64510.1 - 0.057 13.6 5.9 0.12 12.6 5.9 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Torsin PF06309.11 ORX64510.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin PhoH PF02562.16 ORX64510.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ORX64510.1 - 0.076 12.3 0.1 8.9 5.6 0.0 2.3 1 1 1 2 2 2 0 KaiC TniB PF05621.11 ORX64510.1 - 0.079 12.4 0.0 14 5.0 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 ORX64510.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 ORX64510.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORX64510.1 - 0.16 11.7 0.0 0.53 10.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 ORX64510.1 - 0.48 10.3 3.4 1.8 8.4 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TPR_2 PF07719.17 ORX64510.1 - 0.7 10.2 3.7 1.1 9.6 0.5 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat PRP3 PF08572.10 ORX64511.1 - 5.6e-76 255.2 6.8 5.6e-76 255.2 6.8 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ORX64511.1 - 1.4e-44 151.7 0.2 1.4e-44 151.7 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF2407 PF10302.9 ORX64511.1 - 0.48 11.0 2.7 1.8 9.1 0.0 3.0 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain Arrestin_C PF02752.22 ORX64512.1 - 3.7e-12 46.8 0.1 5.5e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX64512.1 - 6.6e-05 23.0 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Nucleos_tra2_C PF07662.13 ORX64521.1 - 8.1e-75 251.2 7.1 8.1e-75 251.2 7.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX64521.1 - 9.2e-24 83.8 3.4 9.2e-24 83.8 3.4 4.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX64521.1 - 0.0046 17.2 8.6 0.0046 17.2 8.6 4.3 3 2 0 3 3 3 1 Nucleoside recognition Protoglobin PF11563.8 ORX64522.1 - 1.1e-37 129.4 0.6 1.3e-37 129.1 0.6 1.0 1 0 0 1 1 1 1 Protoglobin tRNA-synt_1e PF01406.19 ORX64522.1 - 0.12 11.7 0.8 0.14 11.5 0.8 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PX PF00787.24 ORX64522.1 - 0.12 12.3 0.1 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 PX domain Nucleos_tra2_C PF07662.13 ORX64523.1 - 1.9e-74 250.0 7.1 1.9e-74 250.0 7.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX64523.1 - 1.7e-23 83.0 3.4 1.7e-23 83.0 3.4 3.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus ABC_tran PF00005.27 ORX64523.1 - 6.4e-21 75.3 0.0 1.3e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX64523.1 - 9.9e-13 48.6 0.0 3.8e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORX64523.1 - 0.002 17.8 0.2 0.0051 16.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ORX64523.1 - 0.003 17.0 0.0 0.63 9.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 ORX64523.1 - 0.0038 16.0 0.2 0.96 8.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain Gate PF07670.14 ORX64523.1 - 0.0094 16.2 8.6 0.0094 16.2 8.6 4.1 3 2 0 3 3 3 1 Nucleoside recognition MukB PF04310.12 ORX64523.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_23 PF13476.6 ORX64523.1 - 0.054 14.0 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ORX64523.1 - 0.097 12.4 0.1 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORX64523.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 ORX64523.1 - 0.14 11.3 0.1 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ABC_membrane PF00664.23 ORX64531.1 - 1.2e-95 320.3 20.5 2.5e-58 197.9 9.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX64531.1 - 3.9e-70 234.7 0.1 2e-35 122.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX64531.1 - 1.1e-16 61.0 2.2 2e-05 24.1 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX64531.1 - 8.7e-10 38.2 0.3 0.0017 18.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX64531.1 - 1e-09 39.0 0.9 0.0012 19.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORX64531.1 - 1.8e-07 31.2 0.0 0.022 14.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 ORX64531.1 - 2.7e-07 29.7 0.3 0.0042 16.0 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORX64531.1 - 1.7e-06 28.4 2.8 0.011 16.0 0.1 4.2 4 1 0 4 4 3 2 AAA domain AAA PF00004.29 ORX64531.1 - 3.1e-06 27.7 1.1 1.8 9.0 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ORX64531.1 - 1.7e-05 24.8 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORX64531.1 - 2.2e-05 24.3 1.2 0.34 10.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORX64531.1 - 8.9e-05 22.7 5.1 0.24 11.6 0.5 4.5 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 ORX64531.1 - 0.00015 21.8 0.1 0.84 9.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 ORX64531.1 - 0.00016 21.7 0.0 0.12 12.3 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_23 PF13476.6 ORX64531.1 - 0.00017 22.2 0.5 0.87 10.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 ORX64531.1 - 0.00031 20.5 1.0 3.6 7.3 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein G-alpha PF00503.20 ORX64531.1 - 0.00035 19.9 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 ORX64531.1 - 0.00061 19.8 0.2 1.3 9.1 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_7 PF12775.7 ORX64531.1 - 0.00073 19.1 0.0 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 ORX64531.1 - 0.00074 19.8 0.0 2 8.6 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_21 PF13304.6 ORX64531.1 - 0.00081 19.3 0.6 2.9 7.6 0.0 3.9 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ORX64531.1 - 0.00095 19.3 0.0 2.5 8.3 0.1 3.1 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 ORX64531.1 - 0.0011 18.1 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) APS_kinase PF01583.20 ORX64531.1 - 0.0023 17.9 0.0 1.6 8.6 0.0 3.2 3 0 0 3 3 2 1 Adenylylsulphate kinase NB-ARC PF00931.22 ORX64531.1 - 0.0023 17.2 0.0 0.9 8.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 ORX64531.1 - 0.0029 18.2 0.0 4.9 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORX64531.1 - 0.0037 16.6 0.1 3.2 7.0 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 ORX64531.1 - 0.011 15.4 0.2 6 6.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORX64531.1 - 0.013 15.2 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORX64531.1 - 0.018 14.4 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 ORX64531.1 - 0.021 14.9 0.2 2.2 8.3 0.1 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain NACHT PF05729.12 ORX64531.1 - 0.029 14.3 1.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 ORX64531.1 - 0.036 14.5 0.0 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 ORX64531.1 - 0.044 13.5 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 ORX64531.1 - 0.046 13.4 0.0 6.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain GHMP_kinases_C PF08544.13 ORX64531.1 - 0.057 13.8 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 GHMP kinases C terminal DUF2057 PF09829.9 ORX64531.1 - 0.064 13.4 0.2 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TniB PF05621.11 ORX64531.1 - 0.072 12.5 0.1 21 4.5 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein SRP54 PF00448.22 ORX64531.1 - 0.085 12.5 0.1 11 5.6 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Halogen_Hydrol PF10112.9 ORX64531.1 - 0.14 12.2 5.4 0.86 9.6 0.2 3.1 3 0 0 3 3 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ATP_bind_1 PF03029.17 ORX64531.1 - 0.16 11.7 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Uricase PF01014.18 ORX64533.1 - 1.9e-16 60.5 0.9 2e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Uricase DUF3472 PF11958.8 ORX64534.1 - 2.4e-13 50.9 1.3 4.3e-13 50.1 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX64534.1 - 2.5e-07 31.0 14.1 6.1e-07 29.8 14.1 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF4937 PF16291.5 ORX64534.1 - 0.014 15.7 0.4 0.035 14.3 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 PTR2 PF00854.21 ORX64578.1 - 8.5e-80 268.5 6.7 8.5e-80 268.5 6.7 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX64578.1 - 1.1e-12 47.6 32.6 3.4e-08 32.8 9.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Asp PF00026.23 ORX64579.1 - 2e-49 168.7 4.8 4e-49 167.8 4.8 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX64579.1 - 1.4e-08 35.2 8.0 0.0019 18.5 8.0 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX64579.1 - 0.015 15.1 0.1 0.32 10.7 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal PTR2 PF00854.21 ORX64580.1 - 9.9e-80 268.3 7.1 9.9e-80 268.3 7.1 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX64580.1 - 1.9e-14 53.4 26.9 2e-08 33.6 8.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Acetyltransf_7 PF13508.7 ORX64581.1 - 1.6e-11 44.5 0.0 2.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX64581.1 - 3e-10 40.3 0.0 6.3e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX64581.1 - 1.1e-05 25.4 0.0 3.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain C_Hendra PF16821.5 ORX64586.1 - 0.025 14.5 0.5 0.025 14.5 0.5 2.3 3 0 0 3 3 3 0 C protein from hendra and measles viruses DUF3535 PF12054.8 ORX64586.1 - 1.2 8.3 6.2 0.072 12.3 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) Helicase_C PF00271.31 ORX64587.1 - 2.9e-11 43.7 0.0 3.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TEX19 PF15553.6 ORX64589.1 - 0.065 13.2 2.2 0.32 10.9 0.6 2.0 2 0 0 2 2 2 0 Testis-expressed protein 19 FAM176 PF14851.6 ORX64589.1 - 3.7 7.2 6.8 1.5 8.4 2.2 2.0 2 0 0 2 2 2 0 FAM176 family DJ-1_PfpI PF01965.24 ORX64651.1 - 2.1e-08 34.1 0.0 7.9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX64651.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX64651.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DUF3472 PF11958.8 ORX64652.1 - 0.00021 21.8 0.2 0.00033 21.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX64652.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) DUF5077 PF16871.5 ORX64653.1 - 0.0092 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) HSP70 PF00012.20 ORX64665.1 - 2.5e-119 399.2 2.6 2.9e-119 399.0 2.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX64665.1 - 1.6e-11 43.6 0.0 2.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 ORX64665.1 - 0.00042 19.5 0.0 0.031 13.3 0.0 2.5 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; MAPKK1_Int PF08923.10 ORX64665.1 - 0.0075 16.1 0.1 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Mitogen-activated protein kinase kinase 1 interacting DUF2274 PF10038.9 ORX64665.1 - 0.036 14.5 1.4 0.34 11.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) DUF4646 PF15496.6 ORX64666.1 - 1.4e-29 103.3 0.7 2.3e-29 102.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) SR-25 PF10500.9 ORX64666.1 - 0.002 17.7 8.1 0.002 17.7 8.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 ORX64666.1 - 0.0053 17.4 1.1 0.0053 17.4 1.1 2.4 2 1 0 2 2 2 1 Immortalisation up-regulated protein Metal_resist PF13801.6 ORX64666.1 - 0.18 12.0 6.6 1.1 9.5 4.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Erf4 PF10256.9 ORX64666.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family UPF0767 PF15990.5 ORX64666.1 - 2.1 8.5 3.6 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 UPF0767 family TT_ORF1 PF02956.14 ORX64666.1 - 6 5.4 10.1 8.5 4.9 10.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 F-box-like PF12937.7 ORX64667.1 - 5.3e-12 45.4 1.8 1e-11 44.5 1.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX64667.1 - 7.4e-09 35.3 0.7 1.9e-08 34.0 0.2 2.0 1 1 1 2 2 2 1 F-box domain F-box_4 PF15966.5 ORX64667.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box NFACT-R_1 PF05670.13 ORX64667.1 - 0.14 12.8 0.1 0.23 12.1 0.1 1.3 1 0 0 1 1 1 0 NFACT protein RNA binding domain FERM_C PF09380.10 ORX64667.1 - 0.19 12.1 1.7 0.38 11.2 1.0 2.0 2 1 0 2 2 2 0 FERM C-terminal PH-like domain Sugar_tr PF00083.24 ORX64668.1 - 7.3e-102 341.5 27.0 9.9e-102 341.1 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX64668.1 - 4.4e-28 98.2 24.8 4.4e-28 98.2 24.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4229 PF14012.6 ORX64668.1 - 3.1 8.0 8.2 0.35 11.0 1.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) Catalase PF00199.19 ORX64669.1 - 8.6e-176 584.7 0.1 7.3e-175 581.6 0.0 1.9 2 0 0 2 2 2 1 Catalase Catalase_C PF18011.1 ORX64669.1 - 5.3e-32 110.6 0.0 8.6e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORX64669.1 - 2.1e-20 72.7 0.1 6.1e-20 71.2 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 ORX64669.1 - 2e-07 31.0 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4646 PF15496.6 ORX64670.1 - 4.5e-29 101.6 0.6 7e-29 101.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) SR-25 PF10500.9 ORX64670.1 - 0.002 17.7 8.1 0.002 17.7 8.1 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Erf4 PF10256.9 ORX64670.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Metal_resist PF13801.6 ORX64670.1 - 0.15 12.3 6.5 1.1 9.5 4.1 2.3 2 0 0 2 2 2 0 Heavy-metal resistance UPF0767 PF15990.5 ORX64670.1 - 1.1 9.5 3.1 2 8.6 0.0 2.2 2 0 0 2 2 2 0 UPF0767 family F-box-like PF12937.7 ORX64671.1 - 1.4e-09 37.7 1.0 2.7e-09 36.8 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX64671.1 - 8.6e-08 31.9 0.2 2.2e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORX64671.1 - 0.039 13.8 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box E1-E2_ATPase PF00122.20 ORX64691.1 - 1.1e-43 148.8 8.1 1.9e-42 144.8 4.5 3.0 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 ORX64691.1 - 1.6e-18 67.8 0.1 7.8e-18 65.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX64691.1 - 1.3e-12 47.2 0.0 3.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX64691.1 - 0.01 15.6 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase OAD_gamma PF04277.13 ORX64691.1 - 3.1 8.4 7.1 6.9 7.3 2.4 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Polysacc_deac_1 PF01522.21 ORX64765.1 - 6.8e-27 93.8 0.0 9.9e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX64765.1 - 1.7e-11 44.4 57.0 1.2e-06 28.9 19.2 2.9 3 0 0 3 3 3 2 Chitin recognition protein DUF2334 PF10096.9 ORX64765.1 - 0.051 13.2 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) UNC-93 PF05978.16 ORX64766.1 - 8e-05 22.4 9.3 8e-05 22.4 9.3 3.1 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 RNA_pol_A_CTD PF03118.15 ORX64767.1 - 0.098 12.4 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORX64768.1 - 0.086 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain PX PF00787.24 ORX64778.1 - 9.2e-24 83.6 0.9 9.2e-24 83.6 0.9 2.1 3 0 0 3 3 2 1 PX domain Vps5 PF09325.10 ORX64778.1 - 9.8e-15 54.7 16.3 4.6e-08 32.9 2.4 2.3 1 1 1 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 ORX64778.1 - 0.0016 18.2 12.2 0.033 13.9 4.5 3.2 1 1 2 3 3 3 1 BAR domain of APPL family DUF4164 PF13747.6 ORX64778.1 - 0.0057 16.9 3.8 0.074 13.3 0.7 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Snurportin1 PF11538.8 ORX64778.1 - 0.0066 16.6 2.7 0.24 11.6 0.1 3.1 2 0 0 2 2 2 1 Snurportin1 SpecificRecomb PF10136.9 ORX64778.1 - 0.0076 14.6 2.8 0.014 13.8 1.1 1.8 1 1 1 2 2 2 1 Site-specific recombinase DUF4665 PF15679.5 ORX64778.1 - 0.029 15.0 2.9 0.071 13.7 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) LemA PF04011.12 ORX64778.1 - 0.033 14.1 1.2 0.39 10.6 0.0 2.9 2 2 1 3 3 3 0 LemA family DASH_Dam1 PF08653.10 ORX64778.1 - 0.045 13.6 0.4 0.4 10.5 0.1 2.6 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF4685 PF15737.5 ORX64778.1 - 0.088 13.3 0.9 0.27 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) YusW PF14039.6 ORX64778.1 - 0.18 12.3 4.5 0.2 12.2 0.7 2.5 2 0 0 2 2 2 0 YusW-like protein BLOC1_2 PF10046.9 ORX64778.1 - 0.2 12.0 7.9 4.2 7.7 1.8 3.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 ORX64778.1 - 0.46 11.0 4.0 4.3 7.9 0.1 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Nif11 PF07862.11 ORX64778.1 - 0.53 10.6 0.1 0.53 10.6 0.1 2.9 3 0 0 3 3 3 0 Nif11 domain Phage_GPO PF05929.11 ORX64778.1 - 0.59 9.7 10.7 0.03 13.9 1.5 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Sec34 PF04136.15 ORX64778.1 - 0.65 9.9 8.9 0.089 12.7 2.7 2.5 2 2 0 2 2 2 0 Sec34-like family Fzo_mitofusin PF04799.13 ORX64778.1 - 0.73 9.4 5.1 0.69 9.5 0.8 2.7 3 0 0 3 3 3 0 fzo-like conserved region Occludin_ELL PF07303.13 ORX64778.1 - 0.86 10.4 12.8 2.9 8.7 0.2 3.7 2 1 4 6 6 5 0 Occludin homology domain ORF6C PF10552.9 ORX64778.1 - 1.1 9.4 6.0 5 7.3 1.2 2.7 2 0 0 2 2 2 0 ORF6C domain RhoGEF PF00621.20 ORX64778.1 - 1.1 9.5 14.2 0.093 13.0 7.4 2.4 2 1 1 3 3 3 0 RhoGEF domain XhlA PF10779.9 ORX64778.1 - 1.7 8.9 5.3 7.3 6.9 0.3 2.9 2 1 0 2 2 2 0 Haemolysin XhlA P4Ha_N PF08336.11 ORX64778.1 - 2.9 7.9 9.9 1.5 8.8 0.5 3.2 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PHM7_cyt PF14703.6 ORX64778.1 - 6.9 6.9 10.3 0.56 10.4 3.3 2.2 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter APG6_N PF17675.1 ORX64778.1 - 8.8 6.9 20.9 0.093 13.3 3.9 3.0 1 1 1 2 2 1 0 Apg6 coiled-coil region Ribosomal_S21e PF01249.18 ORX64779.1 - 3.2e-40 136.1 0.0 3.6e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4325 PF14213.6 ORX64779.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) PAT1 PF09770.9 ORX64780.1 - 4.1e-132 442.3 18.2 4.2e-114 382.7 6.7 3.0 2 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 ATP_Ca_trans_C PF12424.8 ORX64780.1 - 0.2 12.2 2.5 0.21 12.1 0.7 2.0 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal COX7C PF02935.16 ORX64781.1 - 1.3e-14 54.2 0.3 1.3e-14 54.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc ABC_membrane PF00664.23 ORX64838.1 - 3.1e-36 125.4 9.8 4.4e-36 125.0 9.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORX64838.1 - 8.1e-36 123.6 0.0 1.8e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORX64838.1 - 4.4e-10 39.4 0.1 6.6e-08 32.3 0.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX64838.1 - 5.7e-05 23.6 0.1 0.00015 22.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORX64838.1 - 0.00024 21.0 0.1 0.0011 18.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORX64838.1 - 0.00068 19.9 0.1 0.0029 17.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORX64838.1 - 0.00074 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORX64838.1 - 0.00097 18.8 0.4 0.0023 17.6 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 ORX64838.1 - 0.0011 18.2 0.1 0.0025 17.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 ORX64838.1 - 0.0029 18.0 0.0 0.16 12.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 ORX64838.1 - 0.0051 16.7 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 ORX64838.1 - 0.0071 16.1 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ORX64838.1 - 0.019 15.5 0.5 0.11 13.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 ORX64838.1 - 0.02 13.8 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 ORX64838.1 - 0.03 14.1 0.6 0.08 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORX64838.1 - 0.033 14.3 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORX64838.1 - 0.035 14.2 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORX64838.1 - 0.042 13.8 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORX64838.1 - 0.043 14.1 0.2 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORX64838.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 ORX64838.1 - 0.082 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ferlin_C PF16165.5 ORX64838.1 - 0.099 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Ferlin C-terminus AAA_14 PF13173.6 ORX64838.1 - 0.11 12.6 0.4 0.61 10.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 ORX64838.1 - 0.13 12.5 0.2 3.1 8.1 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ORX64838.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 ORX64838.1 - 0.15 12.1 0.7 1.2 9.1 0.0 2.5 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF5510 PF17629.2 ORX64838.1 - 0.62 10.0 4.4 0.17 11.8 0.6 2.0 2 0 0 2 2 1 0 Family of unknown function (DUF5510) AAA PF00004.29 ORX64840.1 - 8e-40 136.3 0.3 1.5e-38 132.2 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX64840.1 - 4.4e-14 52.0 0.1 1.3e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 ORX64840.1 - 2.8e-08 33.6 0.1 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 ORX64840.1 - 2.4e-05 24.5 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORX64840.1 - 7.5e-05 22.5 0.0 0.00045 20.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORX64840.1 - 0.00013 22.0 0.5 0.008 16.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX64840.1 - 0.00018 21.8 0.2 0.0041 17.4 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX64840.1 - 0.00021 21.7 0.1 0.00089 19.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 ORX64840.1 - 0.00062 19.1 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORX64840.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORX64840.1 - 0.0044 16.4 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORX64840.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORX64840.1 - 0.0054 16.1 0.1 0.51 9.6 0.1 2.6 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.17 ORX64840.1 - 0.0073 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ORX64840.1 - 0.02 15.0 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORX64840.1 - 0.021 14.5 0.1 0.36 10.5 0.1 2.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 ORX64840.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORX64840.1 - 0.04 14.3 0.1 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 ORX64840.1 - 0.048 14.2 0.0 0.048 14.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 ORX64840.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORX64840.1 - 0.061 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ORX64840.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 ORX64840.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 ORX64840.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ORX64840.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX64840.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase Parvo_NS1 PF01057.17 ORX64840.1 - 0.14 11.2 0.2 0.62 9.1 0.1 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 ORX64840.1 - 0.15 11.9 0.0 0.42 10.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CBAH PF02275.18 ORX64870.1 - 0.046 13.4 0.1 0.062 12.9 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Ribosomal_L3 PF00297.22 ORX64909.1 - 3e-74 250.2 1.2 3.4e-74 250.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 V-ATPase_G PF03179.15 ORX64910.1 - 5.3e-31 107.3 18.4 6.1e-31 107.1 18.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 ORX64910.1 - 0.0046 17.4 18.5 0.27 11.7 2.9 2.6 1 1 1 2 2 2 2 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.18 ORX64910.1 - 0.0049 16.3 14.7 0.0054 16.2 14.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3552 PF12072.8 ORX64910.1 - 0.0052 16.2 15.7 0.0065 15.9 15.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 ORX64910.1 - 0.0068 16.5 12.9 0.0068 16.5 12.9 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) OMS28_porin PF03532.13 ORX64910.1 - 0.027 13.7 5.1 0.033 13.4 5.1 1.2 1 0 0 1 1 1 0 OMS28 porin Sds3 PF08598.11 ORX64910.1 - 0.16 11.9 8.1 0.44 10.5 7.9 1.6 1 1 1 2 2 2 0 Sds3-like DUF515 PF04415.12 ORX64910.1 - 0.59 8.5 8.5 0.66 8.3 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SAM_Exu PF18609.1 ORX64910.1 - 0.72 10.0 4.2 0.57 10.3 0.3 2.4 1 1 0 2 2 2 0 Exuperantia SAM-like domain CENP-I PF07778.11 ORX64910.1 - 1.5 7.4 6.9 1.8 7.2 6.9 1.0 1 0 0 1 1 1 0 Mis6 UQ_con PF00179.26 ORX64911.1 - 3.9e-42 143.2 0.0 4.4e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 ORX64911.1 - 0.0045 15.9 0.1 0.007 15.2 0.1 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Prok-E2_B PF14461.6 ORX64911.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 ORX64911.1 - 0.13 12.5 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 RWD domain Acetyltransf_1 PF00583.25 ORX64912.1 - 0.0002 21.6 0.0 0.00023 21.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX64912.1 - 0.17 12.3 0.0 0.56 10.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GCV_T PF01571.21 ORX64913.1 - 1.3e-86 290.2 0.0 1.8e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORX64913.1 - 2.9e-21 75.2 0.1 5.4e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 ORX64913.1 - 2e-05 24.8 0.4 0.0012 19.0 0.0 2.7 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family DUF3659 PF12396.8 ORX64913.1 - 0.13 12.2 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) UQ_con PF00179.26 ORX64914.1 - 2.5e-43 147.1 0.0 2.8e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ORX64914.1 - 0.00095 18.8 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_E PF14462.6 ORX64914.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family E Prok-E2_B PF14461.6 ORX64914.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Arrestin_C PF02752.22 ORX64915.1 - 2.1e-07 31.5 0.3 0.00014 22.3 0.1 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX64915.1 - 0.014 15.4 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX64915.1 - 0.015 15.0 0.1 0.076 12.7 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like AMP-binding PF00501.28 ORX64916.1 - 7.9e-106 354.2 0.0 1.1e-105 353.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Tyr-DNA_phospho PF06087.12 ORX64917.1 - 4.7e-38 131.2 0.0 5.9e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase CCDC-167 PF15188.6 ORX64950.1 - 0.0063 16.8 1.3 0.015 15.6 1.3 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Csm1_N PF18504.1 ORX64950.1 - 0.11 12.9 5.9 0.11 12.9 1.7 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Med9 PF07544.13 ORX64950.1 - 0.33 11.1 4.6 0.88 9.7 1.1 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 ORX64950.1 - 0.36 11.0 2.7 0.79 9.9 1.8 2.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Lig_chan PF00060.26 ORX64951.1 - 0.14 12.0 0.4 0.17 11.7 0.4 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel FXR_C1 PF16096.5 ORX64952.1 - 1.3 9.3 11.8 4.5 7.6 6.3 2.2 1 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Peptidase_S8 PF00082.22 ORX64970.1 - 1.2e-39 136.4 22.3 1.6e-35 122.8 18.8 2.6 2 1 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 ORX64970.1 - 2.3e-07 31.4 0.2 4.5e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX64970.1 - 0.034 14.2 0.3 0.062 13.4 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX64971.1 - 5.5e-36 124.4 18.9 1.7e-35 122.7 18.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX64971.1 - 1.8e-07 31.7 0.2 3.6e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX64971.1 - 0.027 14.6 0.3 0.051 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX64972.1 - 5.4e-36 124.4 18.9 1.7e-35 122.7 18.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX64972.1 - 1.8e-07 31.7 0.2 3.6e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX64972.1 - 0.027 14.5 0.3 0.05 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein HMA PF00403.26 ORX64973.1 - 2.1e-16 60.1 1.0 2.3e-16 60.0 1.0 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain NapD PF03927.13 ORX64973.1 - 0.0028 17.7 0.1 0.0035 17.4 0.1 1.1 1 0 0 1 1 1 1 NapD protein Fer2_BFD PF04324.15 ORX64973.1 - 0.036 14.4 1.6 0.22 11.9 0.1 2.2 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_S8 PF00082.22 ORX64974.1 - 3.1e-36 125.2 18.9 9.5e-36 123.6 18.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX64974.1 - 0.00013 22.5 0.4 0.0017 19.0 0.1 2.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 ORX64975.1 - 5.7e-17 61.9 10.7 2.1e-16 60.0 10.7 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX64975.1 - 1e-07 32.5 0.2 2.1e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX64975.1 - 0.016 15.3 0.3 0.028 14.5 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein DJ-1_PfpI PF01965.24 ORX64992.1 - 2.1e-08 34.1 0.0 7.9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX64992.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX64992.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX64993.1 - 2.1e-08 34.1 0.0 7.9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX64993.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX64993.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DUF1100 PF06500.11 ORX64994.1 - 2.3e-09 36.6 0.0 3.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 ORX64994.1 - 9.2e-08 32.9 0.0 5.4e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORX64994.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ORX64994.1 - 4e-06 26.3 0.1 3.4e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORX64994.1 - 1.3e-05 24.8 0.1 0.0001 21.9 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORX64994.1 - 1.8e-05 24.5 0.1 9.7e-05 22.1 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 ORX64994.1 - 1.9e-05 23.5 0.0 0.0009 18.0 0.0 2.2 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) UPF0227 PF05728.12 ORX64994.1 - 0.0003 20.8 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 ORX64994.1 - 0.032 13.8 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peripla_BP_6 PF13458.6 ORX64994.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_2 PF02230.16 ORX64994.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_M75 PF09375.10 ORX64994.1 - 0.2 11.1 1.4 0.35 10.3 1.4 1.3 1 0 0 1 1 1 0 Imelysin ThiJ_like PF17124.5 ORX64995.1 - 0.00067 19.4 0.0 0.00078 19.2 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX64995.1 - 0.00086 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Latrotoxin C-terminal domain SOGA PF11365.8 ORX65008.1 - 0.22 12.6 1.5 0.25 12.5 0.2 1.9 2 0 0 2 2 2 0 Protein SOGA Cwf_Cwc_15 PF04889.12 ORX65008.1 - 1.6 8.4 6.7 3.2 7.4 0.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ras PF00071.22 ORX65010.1 - 1.9e-65 219.4 1.2 2.2e-65 219.2 1.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX65010.1 - 1.1e-36 125.7 0.7 1.5e-36 125.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX65010.1 - 1.4e-17 63.7 0.2 1.8e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX65010.1 - 6.6e-06 25.8 0.5 1.7e-05 24.5 0.3 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORX65010.1 - 1e-05 25.1 0.1 1.2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX65010.1 - 1.1e-05 25.4 0.7 0.13 12.2 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 ORX65010.1 - 1.9e-05 24.2 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORX65010.1 - 3.2e-05 24.0 0.0 5.8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORX65010.1 - 0.0033 17.3 0.2 0.0091 15.8 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORX65010.1 - 0.0039 16.7 0.3 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 ORX65010.1 - 0.0059 17.0 0.0 0.32 11.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX65010.1 - 0.0088 16.4 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORX65010.1 - 0.018 15.0 0.1 0.036 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ORX65010.1 - 0.04 14.4 0.1 0.081 13.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ORX65010.1 - 0.043 14.1 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORX65010.1 - 0.046 13.5 0.1 1.1 9.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 ORX65010.1 - 0.047 13.0 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Septin DUF3873 PF12989.7 ORX65010.1 - 0.048 14.0 0.1 0.095 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_29 PF13555.6 ORX65010.1 - 0.054 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORX65010.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein rve PF00665.26 ORX65010.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain MTCP1 PF08991.10 ORX65011.1 - 0.098 12.9 2.7 0.27 11.5 1.5 2.0 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type WD40 PF00400.32 ORX65012.1 - 4.7e-08 33.6 2.8 4e-06 27.4 0.1 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.11 ORX65012.1 - 5.9e-05 23.0 0.2 0.0001 22.3 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORX65012.1 - 0.028 14.7 0.1 0.076 13.3 0.0 1.7 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX65012.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.32 ORX65013.1 - 8.7e-14 51.7 2.2 4.9e-08 33.5 0.1 3.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX65013.1 - 0.0023 18.2 0.3 0.13 12.6 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 ORX65013.1 - 0.016 13.9 0.0 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SGL PF08450.12 ORX65013.1 - 0.034 13.7 0.1 0.046 13.3 0.1 1.4 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region ABC_membrane PF00664.23 ORX65020.1 - 6.1e-132 439.3 31.5 2.3e-67 227.5 13.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX65020.1 - 7.2e-64 214.4 0.1 1.9e-35 122.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX65020.1 - 4.1e-14 52.6 10.1 1.4e-05 24.7 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX65020.1 - 1.6e-07 31.0 0.2 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORX65020.1 - 2.2e-07 30.1 2.7 0.0006 18.7 0.1 2.7 3 0 0 3 3 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORX65020.1 - 1.6e-06 28.4 0.6 0.12 12.7 0.2 3.8 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 ORX65020.1 - 2.7e-06 26.8 0.2 0.049 12.8 0.0 2.5 3 0 0 3 3 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 ORX65020.1 - 2.9e-06 27.3 0.7 0.06 13.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 ORX65020.1 - 7.2e-06 25.9 0.1 0.0072 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORX65020.1 - 1.6e-05 24.2 0.1 0.019 14.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 ORX65020.1 - 2.4e-05 24.8 7.8 0.062 13.7 1.1 3.9 2 2 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 ORX65020.1 - 4.4e-05 23.7 0.2 0.22 11.6 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_7 PF12775.7 ORX65020.1 - 5.2e-05 22.8 0.1 0.2 11.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 ORX65020.1 - 0.00012 22.2 2.9 0.71 10.2 0.3 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ORX65020.1 - 0.00019 21.2 0.2 2.2 8.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 ORX65020.1 - 0.00023 20.6 0.1 0.84 8.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF815 PF05673.13 ORX65020.1 - 0.00027 20.2 0.1 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA PF00004.29 ORX65020.1 - 0.00066 20.1 0.1 5.9 7.3 0.0 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX65020.1 - 0.00092 19.2 0.1 2.9 7.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORX65020.1 - 0.0015 19.1 0.1 1.4 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORX65020.1 - 0.0018 18.0 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX65020.1 - 0.0023 18.1 0.0 4.1 7.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 ORX65020.1 - 0.0035 17.1 0.5 2.9 7.6 0.0 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase PRK PF00485.18 ORX65020.1 - 0.0042 16.8 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 ORX65020.1 - 0.0051 17.0 0.7 3.4 7.9 0.0 3.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORX65020.1 - 0.0091 16.3 0.1 7.5 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 ORX65020.1 - 0.016 15.0 0.1 9.3 6.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORX65020.1 - 0.018 15.1 0.2 5.3 7.2 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORX65020.1 - 0.019 14.7 0.1 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 ORX65020.1 - 0.021 14.7 0.0 6 6.7 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Ploopntkinase3 PF18751.1 ORX65020.1 - 0.034 14.0 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FumaraseC_C PF10415.9 ORX65020.1 - 0.053 13.9 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Fumarase C C-terminus AAA_25 PF13481.6 ORX65020.1 - 0.056 13.0 0.1 9.4 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 ORX65020.1 - 0.058 13.3 0.1 12 5.8 0.0 2.9 3 0 0 3 3 2 0 NACHT domain Mg_chelatase PF01078.21 ORX65020.1 - 0.069 12.5 0.0 3.1 7.1 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ORX65020.1 - 0.07 13.0 0.0 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 ORX65020.1 - 0.076 12.2 0.9 4.8 6.3 0.4 2.8 2 1 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 ORX65020.1 - 0.078 12.9 0.1 17 5.2 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 ORX65020.1 - 0.12 12.8 0.0 21 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX65020.1 - 0.13 12.6 0.1 26 5.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NDUF_B12 PF08122.12 ORX65020.1 - 0.95 9.6 7.0 0.54 10.3 0.1 3.0 3 0 0 3 3 2 0 NADH-ubiquinone oxidoreductase B12 subunit family CobD_Cbib PF03186.13 ORX65020.1 - 9.4 5.3 8.4 4.2 6.5 2.3 3.1 2 1 1 3 3 3 0 CobD/Cbib protein Vps53_N PF04100.12 ORX65032.1 - 3.2e-109 365.4 16.6 3.2e-109 365.4 16.6 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 ORX65032.1 - 2.3e-05 23.9 8.8 2.3e-05 23.9 8.8 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 ORX65032.1 - 0.00023 21.1 0.9 0.0028 17.6 0.0 2.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 ORX65032.1 - 0.0032 16.4 7.4 0.0032 16.4 7.4 1.8 2 1 0 2 2 2 1 Spc7 kinetochore protein RecG_N PF17190.4 ORX65032.1 - 9.4 7.0 10.6 0.29 11.9 1.3 3.2 3 0 0 3 3 3 0 RecG N-terminal helical domain CDC73_C PF05179.14 ORX65033.1 - 7e-52 175.3 1.7 7e-52 175.3 1.7 1.6 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 ORX65033.1 - 1.9e-23 83.3 6.1 4.3e-21 75.5 0.4 2.4 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal SnoaL_4 PF13577.6 ORX65033.1 - 0.038 14.1 0.2 0.07 13.3 0.2 1.3 1 0 0 1 1 1 0 SnoaL-like domain GREB1 PF15782.5 ORX65033.1 - 0.39 7.8 4.2 0.52 7.4 4.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Myb_DNA-binding PF00249.31 ORX65034.1 - 4.6e-07 29.9 0.0 9.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORX65034.1 - 5.1e-07 29.4 9.9 7.8e-07 28.8 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 ORX65034.1 - 0.0012 19.0 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cytochrom_C PF00034.21 ORX65034.1 - 1.2 10.4 3.8 3.7 8.8 0.1 3.4 4 0 0 4 4 4 0 Cytochrome c IU_nuc_hydro PF01156.19 ORX65074.1 - 1.1e-63 215.6 0.0 1.4e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aa_trans PF01490.18 ORX65075.1 - 2.6e-92 309.6 16.9 3e-92 309.5 16.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX65075.1 - 6.1e-06 25.5 8.5 6.1e-06 25.5 8.5 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family IU_nuc_hydro PF01156.19 ORX65076.1 - 4.8e-62 210.3 0.0 5.8e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Uricase PF01014.18 ORX65077.1 - 2.6e-64 215.4 4.1 1.1e-36 126.0 2.3 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORX65077.1 - 0.024 15.2 0.4 0.059 13.9 0.4 1.7 1 0 0 1 1 1 0 Dihydroneopterin aldolase Uricase PF01014.18 ORX65078.1 - 0.0051 17.1 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 Uricase Skp1_POZ PF03931.15 ORX65103.1 - 6.7e-10 39.0 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 ORX65103.1 - 0.033 14.4 0.1 0.048 13.9 0.1 1.3 1 1 0 1 1 1 0 BTB/POZ domain Rif1_N PF12231.8 ORX65103.1 - 0.076 12.0 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal ELFV_dehydrog PF00208.21 ORX65104.1 - 4.7e-22 78.9 0.6 9.7e-10 38.6 0.0 3.0 1 1 2 3 3 3 3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Inhibitor_I36 PF03995.13 ORX65104.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Ribosomal_L3 PF00297.22 ORX65131.1 - 7.2e-06 25.2 0.3 0.033 13.2 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 zf-H2C2_2 PF13465.6 ORX65144.1 - 1.4e-17 63.3 22.6 6.3e-09 35.9 3.1 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX65144.1 - 2.8e-16 59.0 19.1 1.5e-06 28.3 2.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX65144.1 - 4.5e-08 33.3 25.1 0.00022 21.8 2.1 3.5 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX65144.1 - 3.7e-07 30.3 5.5 0.032 14.5 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORX65144.1 - 0.00034 20.3 16.7 1.7 8.4 6.8 4.3 3 1 0 3 3 3 3 C2H2-type zinc-finger domain FOXP-CC PF16159.5 ORX65144.1 - 0.0027 18.3 2.0 0.025 15.2 0.1 2.6 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-met PF12874.7 ORX65144.1 - 0.044 14.2 11.9 0.93 10.0 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HypA PF01155.19 ORX65144.1 - 0.06 13.4 0.4 0.068 13.2 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 ORX65144.1 - 0.087 13.3 1.9 0.17 12.4 1.9 1.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 ORX65144.1 - 0.18 11.4 0.2 0.18 11.4 0.2 2.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 ORX65144.1 - 0.2 11.6 9.2 1.2 9.1 0.5 3.4 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger A_deaminase PF00962.22 ORX65144.1 - 0.23 10.7 1.4 0.88 8.8 1.4 1.8 1 1 0 1 1 1 0 Adenosine/AMP deaminase zf-CGNR PF11706.8 ORX65144.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.3 3 0 0 3 3 3 0 CGNR zinc finger zf-C2H2_11 PF16622.5 ORX65144.1 - 0.38 10.6 11.8 0.36 10.6 1.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type MCM_OB PF17207.3 ORX65144.1 - 0.39 10.6 2.9 0.17 11.7 1.4 1.4 1 1 0 1 1 1 0 MCM OB domain zf-C2H2_6 PF13912.6 ORX65144.1 - 0.8 9.8 10.5 0.22 11.6 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.23 ORX65157.1 - 8.2e-48 162.9 0.0 1.3e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX65157.1 - 5.9e-20 71.7 0.9 1.4e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX65157.1 - 5.7e-06 26.4 0.0 2.2e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 ORX65157.1 - 0.0091 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain SWI2_SNF2 PF18766.1 ORX65157.1 - 0.02 14.6 0.1 4 7.0 0.0 3.0 3 0 0 3 3 3 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 ORX65157.1 - 0.049 12.8 0.0 0.049 12.8 0.0 2.1 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Phage_TAC_1 PF06222.11 ORX65157.1 - 0.12 12.2 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone MGC-24 PF05283.11 ORX65157.1 - 6.6 7.2 10.0 14 6.2 10.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Med12-LCEWAV PF12145.8 ORX65273.1 - 0.086 11.7 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain CBM_5_12 PF02839.14 ORX65304.1 - 4.2e-06 27.0 10.4 4.2e-06 27.0 10.4 2.1 2 1 1 3 3 3 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX65304.1 - 0.0086 16.0 5.9 0.012 15.6 5.9 1.4 1 1 0 1 1 1 1 Cellulose-binding domain Glyco_hydro_18 PF00704.28 ORX65305.1 - 1.8e-51 175.7 0.0 2.1e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Macoilin PF09726.9 ORX65306.1 - 4.8 5.6 15.2 4.9 5.6 15.2 1.1 1 0 0 1 1 1 0 Macoilin family ydhR PF08803.11 ORX65307.1 - 4.6e-39 132.2 0.0 5.1e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR DUF4448 PF14610.6 ORX65308.1 - 2.2e-06 27.6 0.0 4.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4690 PF15756.5 ORX65308.1 - 0.074 13.7 0.5 0.2 12.3 0.5 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage TAFII28 PF04719.14 ORX65309.1 - 1.5e-31 108.3 0.0 1.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF5501 PF17605.2 ORX65309.1 - 0.053 13.9 0.0 0.089 13.2 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5501) FMN_red PF03358.15 ORX65326.1 - 5.5e-08 32.7 0.0 8.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase CsbD PF05532.12 ORX65327.1 - 2.9e-11 43.1 6.2 1.7e-05 24.7 0.6 2.2 2 0 0 2 2 2 2 CsbD-like Cluap1 PF10234.9 ORX65328.1 - 0.0087 15.5 9.4 0.014 14.9 9.4 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 KASH_CCD PF14662.6 ORX65328.1 - 0.032 14.1 13.7 0.046 13.5 13.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SOGA PF11365.8 ORX65328.1 - 0.078 14.1 10.1 3.7 8.7 5.7 2.8 2 1 0 2 2 2 0 Protein SOGA TMF_DNA_bd PF12329.8 ORX65328.1 - 0.18 11.8 10.4 0.12 12.4 1.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 ORX65328.1 - 0.19 11.0 6.9 0.27 10.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 ORX65328.1 - 0.54 10.3 13.8 0.097 12.7 4.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 ORX65328.1 - 0.56 9.5 2.7 0.79 9.0 2.7 1.2 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 ORX65328.1 - 0.74 9.6 6.8 1.1 9.0 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 ORX65328.1 - 1 9.2 12.5 3.1 7.6 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF1515 PF07439.11 ORX65328.1 - 1.3 9.1 4.6 0.44 10.6 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 ORX65328.1 - 1.8 8.6 13.4 5.4 7.1 13.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 5_nucleotid PF05761.14 ORX65328.1 - 3.1 6.6 5.0 50 2.6 6.1 1.9 2 0 0 2 2 2 0 5' nucleotidase family Exonuc_VII_L PF02601.15 ORX65328.1 - 3.7 7.0 7.6 5 6.6 7.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 ORX65328.1 - 8.6 7.1 9.4 1.5 9.5 3.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA AbrB PF05145.12 ORX65329.1 - 0.09 11.7 0.0 0.093 11.7 0.0 1.0 1 0 0 1 1 1 0 Transition state regulatory protein AbrB PGM_PMM_I PF02878.16 ORX65330.1 - 9.5e-37 125.8 0.2 1.7e-36 125.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORX65330.1 - 2.6e-29 101.7 0.0 4.8e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORX65330.1 - 6.1e-17 62.1 0.1 1.8e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORX65330.1 - 2.3e-06 27.7 0.0 5.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain IBN_N PF03810.19 ORX65331.1 - 2.9e-05 23.9 0.0 0.00013 21.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 ORX65331.1 - 0.00032 20.0 1.3 0.00032 20.0 1.3 2.6 2 0 0 2 2 2 1 CRM1 C terminal Importin_rep_6 PF18829.1 ORX65331.1 - 0.0096 16.0 1.7 1 9.5 0.0 3.5 3 0 0 3 3 3 1 Importin repeat 6 Xpo1 PF08389.12 ORX65331.1 - 0.076 13.1 6.9 0.75 9.8 0.0 5.1 6 0 0 6 6 6 0 Exportin 1-like protein DUF1836 PF08876.11 ORX65331.1 - 0.11 12.6 0.3 0.62 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) Ank_3 PF13606.6 ORX65372.1 - 0.05 14.2 0.1 28 5.7 0.0 4.3 3 1 1 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 ORX65372.1 - 0.093 13.3 0.7 31 5.2 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) Thiol_cytolysin PF01289.19 ORX65373.1 - 8.1e-34 117.1 0.1 9.5e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Thiol-activated cytolysin Sacchrp_dh_C PF16653.5 ORX65393.1 - 1.6e-98 330.1 0.0 2.2e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORX65393.1 - 4.6e-20 72.2 0.0 9.8e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORX65393.1 - 9.1e-05 22.4 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 ORX65393.1 - 0.00021 21.3 0.0 0.00049 20.2 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 ORX65393.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 ORX65393.1 - 0.043 14.2 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORX65393.1 - 0.12 12.9 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAGPA PF09992.9 ORX65406.1 - 4e-10 40.2 0.9 5.7e-10 39.6 0.9 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase Phage_Coat_Gp8 PF05371.12 ORX65407.1 - 0.32 10.8 1.5 1.7 8.5 0.4 2.8 3 0 0 3 3 3 0 Phage major coat protein, Gp8 DUF998 PF06197.13 ORX65409.1 - 8.7 5.9 11.9 1.1 8.8 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF998) NAD_binding_5 PF07994.12 ORX65450.1 - 1.6e-143 478.0 0.0 1.8e-143 477.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORX65450.1 - 3.1e-46 156.1 0.3 5.7e-46 155.3 0.3 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase RNA_pol_Rpb1_6 PF04992.14 ORX65451.1 - 0.015 15.1 0.2 0.022 14.6 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 DUF4646 PF15496.6 ORX65451.1 - 0.19 12.4 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) 4HBT PF03061.22 ORX65452.1 - 0.015 15.6 0.0 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily Ion_trans PF00520.31 ORX65453.1 - 8.2e-152 503.4 88.2 1.8e-50 171.5 15.3 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 ORX65453.1 - 2.4e-05 23.2 83.9 0.0048 15.6 8.3 8.8 6 3 3 9 9 9 7 Polycystin cation channel GPHH PF16905.5 ORX65453.1 - 0.0002 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated GTF2I PF02946.14 ORX65453.1 - 0.13 12.3 0.1 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 GTF2I-like repeat Sugar_tr PF00083.24 ORX65469.1 - 3.4e-29 102.0 13.0 3.8e-29 101.8 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX65469.1 - 6.6e-08 31.9 16.6 1.2e-07 31.0 16.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 ORX65470.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 ORX65470.1 - 0.033 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin HAMP PF00672.25 ORX65471.1 - 1.6e-40 137.3 8.1 1e-05 25.8 0.0 8.4 8 0 0 8 8 8 7 HAMP domain HATPase_c PF02518.26 ORX65471.1 - 2.2e-31 108.6 0.0 1.2e-30 106.3 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX65471.1 - 2.5e-28 98.5 0.7 5.6e-26 90.9 0.4 2.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORX65471.1 - 7e-17 61.2 0.3 4.7e-16 58.6 0.1 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.10 ORX65471.1 - 0.00019 21.9 0.4 10 6.7 0.1 6.2 6 1 0 6 6 6 1 Domain of unknown function (DUF1843) Laminin_II PF06009.12 ORX65471.1 - 0.001 19.1 26.6 0.3 11.1 1.7 6.4 7 0 0 7 7 7 4 Laminin Domain II GLE1 PF07817.13 ORX65471.1 - 0.0028 16.9 1.5 6.8 5.8 0.0 4.1 2 2 2 4 4 4 1 GLE1-like protein DUF3829 PF12889.7 ORX65471.1 - 0.0053 16.3 2.7 4.7 6.6 0.0 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF3829) Abhydrolase_8 PF06259.12 ORX65471.1 - 0.011 15.3 14.7 0.13 11.9 0.3 4.9 5 1 0 5 5 5 0 Alpha/beta hydrolase Thiamine_BP PF01910.17 ORX65471.1 - 0.063 13.2 7.3 0.29 11.1 0.2 4.2 2 2 3 5 5 5 0 Thiamine-binding protein DUF5344 PF17279.2 ORX65471.1 - 1 10.0 7.9 14 6.3 1.5 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5344) MFS_1 PF07690.16 ORX65472.1 - 6.5e-16 58.2 31.7 6.5e-16 58.2 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX65472.1 - 1.6e-10 41.0 9.5 1.6e-10 41.0 9.5 2.0 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ribosomal_L37ae PF01780.19 ORX65473.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORX65473.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORX65473.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORX65473.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORX65473.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain DUF4203 PF13886.6 ORX65474.1 - 2.7e-38 131.7 35.9 4.6e-38 130.9 34.8 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4203) DUF4538 PF15061.6 ORX65474.1 - 7.6 6.3 5.7 1.9 8.3 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Apolipoprotein PF01442.18 ORX65502.1 - 1.5e-18 67.4 178.0 0.00054 19.9 29.4 6.7 1 1 5 6 6 6 6 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 ORX65502.1 - 2.8e-05 24.1 251.7 0.0025 17.9 13.3 16.0 3 3 14 17 17 17 13 Late embryogenesis abundant protein YtxH PF12732.7 ORX65502.1 - 0.022 15.3 195.5 2.8 8.5 11.4 14.4 2 1 8 10 10 10 0 YtxH-like protein DUF883 PF05957.13 ORX65502.1 - 0.076 13.6 159.6 0.13 12.9 11.9 11.6 3 1 9 12 12 12 0 Bacterial protein of unknown function (DUF883) MTHFR PF02219.17 ORX65503.1 - 3.7e-120 400.6 0.0 4.6e-120 400.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3665 PF12427.8 ORX65503.1 - 0.082 12.6 0.6 0.17 11.6 0.6 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Ribosomal_60s PF00428.19 ORX65504.1 - 2.8e-26 91.9 12.1 3.2e-26 91.7 12.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein L51_S25_CI-B8 PF05047.16 ORX65505.1 - 1.3e-05 25.0 0.3 2.7e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain BIR PF00653.21 ORX65505.1 - 0.025 15.2 0.2 0.049 14.3 0.2 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain GDPD PF03009.17 ORX65551.1 - 1.4e-30 106.9 0.0 1e-28 100.8 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CDC50 PF03381.15 ORX65553.1 - 1.3e-98 330.0 0.0 1.6e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family GPI-anchored PF10342.9 ORX65554.1 - 2.6e-13 50.6 0.4 6.6e-13 49.2 0.0 1.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sporozoite_P67 PF05642.11 ORX65554.1 - 8.1 4.4 12.7 10 4.1 12.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GPI-anchored PF10342.9 ORX65555.1 - 7.3e-14 52.3 1.7 1.2e-13 51.7 0.0 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORX65556.1 - 8.3e-10 39.3 0.2 1.5e-09 38.5 0.0 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_11 PF08241.12 ORX65571.1 - 1.8e-21 76.6 0.0 2.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX65571.1 - 2.7e-19 69.7 0.0 4.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX65571.1 - 7.9e-15 55.0 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX65571.1 - 2.1e-14 53.4 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORX65571.1 - 3.7e-10 40.4 0.0 6.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX65571.1 - 6.6e-07 29.3 0.0 8.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORX65571.1 - 3.9e-06 26.2 0.0 5.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 ORX65571.1 - 0.00035 20.5 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 ORX65571.1 - 0.023 14.2 0.0 0.22 11.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 ORX65571.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ORX65572.1 - 1.2e-21 77.1 0.0 1.9e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX65572.1 - 2.8e-19 69.6 0.0 4.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX65572.1 - 2.9e-15 56.3 0.0 4.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORX65572.1 - 8e-14 51.7 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX65572.1 - 3.5e-09 37.3 0.0 6.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX65572.1 - 2e-07 31.0 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORX65572.1 - 1.5e-06 27.6 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 ORX65572.1 - 0.0011 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ORX65572.1 - 0.0012 17.5 0.0 0.0018 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 ORX65572.1 - 0.0033 17.3 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_PK PF05891.12 ORX65572.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase NodS PF05401.11 ORX65572.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 ORX65572.1 - 0.098 12.2 0.0 0.42 10.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain HSP70 PF00012.20 ORX65573.1 - 2.4e-267 888.0 15.2 2.8e-267 887.8 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX65573.1 - 6e-15 54.9 4.5 7.2e-13 48.0 2.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORX65573.1 - 0.016 15.6 6.3 1.1 9.7 0.2 3.7 3 2 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 ORX65573.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DMRL_synthase PF00885.19 ORX65573.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Spc7 PF08317.11 ORX65573.1 - 0.26 10.1 7.6 0.52 9.2 7.6 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Rad21_Rec8_N PF04825.13 ORX65574.1 - 2.2e-38 130.8 0.0 4e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORX65574.1 - 3.1e-15 55.2 0.4 1e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 ORX65574.1 - 0.02 14.8 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 Segregation and condensation protein ScpA NAC PF01849.18 ORX65575.1 - 1.1e-22 79.7 0.4 2e-22 78.9 0.4 1.4 1 0 0 1 1 1 1 NAC domain Peptidase_C39 PF03412.15 ORX65575.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family Cmc1 PF08583.10 ORX65576.1 - 1.4e-12 47.5 0.8 2.1e-12 46.9 0.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 ORX65576.1 - 0.066 13.5 0.6 0.69 10.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.12 ORX65576.1 - 0.078 12.8 0.9 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 PAN-like domain Atg31 PF09795.9 ORX65577.1 - 0.011 15.7 0.4 0.025 14.6 0.4 1.5 1 1 0 1 1 1 0 Autophagy-related protein 31 FAS_meander PF17951.1 ORX65577.1 - 0.058 13.2 0.1 0.079 12.8 0.1 1.1 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Mo25 PF08569.11 ORX65578.1 - 1.8e-110 369.4 6.1 2e-110 369.2 6.1 1.0 1 0 0 1 1 1 1 Mo25-like Ribosomal_L24e PF01246.20 ORX65579.1 - 4.2e-33 113.4 0.3 4.2e-33 113.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CDPS PF16715.5 ORX65579.1 - 0.43 10.2 5.7 0.62 9.7 5.7 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase DDHD PF02862.17 ORX65579.1 - 1.5 9.0 5.0 1.8 8.6 5.0 1.0 1 0 0 1 1 1 0 DDHD domain ACOX PF01756.19 ORX65646.1 - 3.2e-53 180.0 0.0 5.7e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORX65646.1 - 1.8e-19 69.8 0.1 2.9e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORX65646.1 - 2e-14 54.2 0.0 4.9e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORX65646.1 - 2.8e-07 30.9 0.2 1.5e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CorA PF01544.18 ORX65647.1 - 4.4e-45 154.2 0.8 5e-45 154.0 0.8 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.6 ORX65647.1 - 0.044 14.4 1.7 0.41 11.3 0.1 2.3 2 0 0 2 2 2 0 ACT domain ACOX PF01756.19 ORX65648.1 - 3.2e-53 180.0 0.0 5.7e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORX65648.1 - 1.7e-19 69.8 0.1 2.9e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORX65648.1 - 7.2e-16 58.9 0.0 1.8e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORX65648.1 - 3.2e-07 30.7 0.1 1.6e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-H2C2_2 PF13465.6 ORX65649.1 - 1.4e-11 44.2 3.7 2.2e-09 37.3 0.3 2.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX65649.1 - 6.6e-08 32.8 10.1 2.4e-05 24.8 3.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX65649.1 - 8e-08 32.3 12.1 2.3e-06 27.7 4.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORX65649.1 - 1.1e-06 28.8 2.4 0.028 14.7 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX65649.1 - 4.8e-05 23.6 3.4 0.074 13.5 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORX65649.1 - 0.0017 18.1 5.3 0.0041 16.8 0.9 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-Di19 PF05605.12 ORX65649.1 - 0.011 16.0 2.5 0.013 15.8 2.5 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 ORX65649.1 - 0.026 14.3 9.3 0.13 12.1 9.3 2.1 1 1 0 1 1 1 0 C2H2-type zinc-finger domain DUF2256 PF10013.9 ORX65649.1 - 0.027 14.6 1.6 5.2 7.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 ORX65649.1 - 0.064 13.6 4.6 3.4 8.0 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.9 ORX65649.1 - 0.2 11.4 1.2 6.5 6.4 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.16 ORX65649.1 - 0.38 11.0 9.3 0.28 11.4 3.4 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 ORX65649.1 - 0.48 10.9 4.6 2.5 8.6 1.5 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ORX65649.1 - 0.54 10.2 9.0 0.64 10.0 1.6 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Pribosyl_synth PF14572.6 ORX65650.1 - 3e-43 148.0 1.6 3.1e-41 141.4 1.6 2.2 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORX65650.1 - 5.9e-43 145.5 1.7 2.7e-42 143.4 0.1 2.4 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORX65650.1 - 3e-09 36.6 0.1 5.6e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain O-FucT PF10250.9 ORX65650.1 - 0.04 13.6 0.0 8.4 6.0 0.0 2.1 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase Homeobox_KN PF05920.11 ORX65772.1 - 2e-18 66.0 0.2 2e-18 66.0 0.2 1.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 ORX65772.1 - 3.4e-06 26.8 0.1 4.5e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORX65772.1 - 0.0042 16.5 0.0 0.0061 16.0 0.0 1.5 1 1 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Sin3a_C PF16879.5 ORX65773.1 - 5.5e-77 259.3 5.0 1.6e-76 257.8 2.2 3.1 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORX65773.1 - 8e-44 147.5 15.7 1.4e-16 60.3 0.0 4.1 4 1 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORX65773.1 - 5e-43 145.1 0.3 1.2e-42 143.9 0.3 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PNISR PF15996.5 ORX65773.1 - 0.027 14.7 0.2 0.065 13.5 0.2 1.7 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PTR2 PF00854.21 ORX65797.1 - 2.9e-80 270.0 6.5 2.9e-80 270.0 6.5 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX65797.1 - 1.2e-14 54.1 26.8 7.7e-09 34.9 9.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Malic_M PF03949.15 ORX66099.1 - 2.4e-71 240.0 0.0 3.7e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORX66099.1 - 2.2e-63 213.3 0.0 3.3e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TRAM_LAG1_CLN8 PF03798.16 ORX66100.1 - 2.2e-33 115.7 13.7 2.7e-33 115.4 13.7 1.1 1 0 0 1 1 1 1 TLC domain TIM21 PF08294.11 ORX66101.1 - 7.6e-40 136.1 0.0 9.3e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 ORX66101.1 - 0.00081 19.1 0.0 0.0048 16.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 APH PF01636.23 ORX66102.1 - 7.5e-41 140.6 0.0 9.9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORX66102.1 - 0.00014 21.3 0.0 0.00029 20.2 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 ORX66102.1 - 0.013 14.7 0.0 0.18 10.9 0.0 2.2 1 1 1 2 2 2 0 Fructosamine kinase DUF2264 PF10022.9 ORX66102.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) PBD PF00786.28 ORX66104.1 - 1.8e-22 79.5 0.1 2e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 P21-Rho-binding domain COX7C PF02935.16 ORX66395.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.1 3 1 0 3 3 3 0 Cytochrome c oxidase subunit VIIc Velvet PF11754.8 ORX66396.1 - 4.8e-72 242.9 0.2 2.9e-43 148.6 0.0 2.2 1 1 1 2 2 2 2 Velvet factor Arrestin_N PF00339.29 ORX66397.1 - 4.9e-11 42.9 0.0 2e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX66397.1 - 1.5e-06 28.1 0.0 1.1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_C PF02752.22 ORX66397.1 - 5.3e-05 23.7 0.1 9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DapB_C PF05173.14 ORX66397.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Ribosomal_L5e PF17144.4 ORX66398.1 - 1.4e-86 288.6 0.2 1.4e-86 288.6 0.2 2.7 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORX66398.1 - 3.9e-32 111.1 7.7 3.9e-32 111.1 7.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region G-alpha PF00503.20 ORX66399.1 - 6.4e-109 364.3 2.8 7.8e-109 364.1 2.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX66399.1 - 4.4e-12 45.8 0.4 7.2e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DASH_Dad1 PF08649.10 ORX66399.1 - 0.0089 16.2 1.0 0.068 13.4 0.3 2.4 2 0 0 2 2 2 1 DASH complex subunit Dad1 zf-CHC2 PF01807.20 ORX66399.1 - 0.011 15.5 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger MMR_HSR1 PF01926.23 ORX66399.1 - 0.025 14.7 0.1 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 ORX66399.1 - 0.11 12.7 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Myb_DNA-bind_4 PF13837.6 ORX66400.1 - 5.9e-15 55.4 2.8 5.9e-15 55.4 2.8 2.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX66400.1 - 0.0016 18.5 1.2 0.0016 18.5 1.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Bestrophin PF01062.21 ORX66401.1 - 0.0011 18.4 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel HAP1_N PF04849.13 ORX66677.1 - 1.4e-06 27.8 20.5 2.7e-05 23.5 20.2 2.7 1 1 0 1 1 1 1 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 ORX66677.1 - 1.2e-05 25.5 2.4 1.2e-05 25.5 2.4 3.3 2 1 1 3 3 3 1 Tropomyosin like Prefoldin_3 PF13758.6 ORX66677.1 - 0.0012 18.9 6.9 0.0051 16.8 1.7 2.8 1 1 1 2 2 2 1 Prefoldin subunit Tropomyosin PF00261.20 ORX66677.1 - 0.0037 16.7 1.5 0.0037 16.7 1.5 3.3 2 1 2 4 4 4 2 Tropomyosin Caudo_TAP PF02413.17 ORX66677.1 - 0.009 16.2 2.8 0.011 15.9 1.3 1.9 1 1 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Snapin_Pallidin PF14712.6 ORX66677.1 - 0.043 14.2 0.3 0.043 14.2 0.3 3.7 3 2 0 3 3 2 0 Snapin/Pallidin IFT57 PF10498.9 ORX66677.1 - 0.047 12.6 17.7 0.66 8.9 5.4 2.9 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 GIT_CC PF16559.5 ORX66677.1 - 0.059 13.2 0.2 0.059 13.2 0.2 2.7 3 1 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 ORX66677.1 - 0.12 11.7 2.1 0.21 10.9 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 ORX66677.1 - 0.14 12.2 15.4 0.38 10.8 4.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 ORX66677.1 - 0.19 11.5 4.8 21 4.8 4.8 2.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain COG2 PF06148.11 ORX66677.1 - 0.41 10.7 7.1 0.35 11.0 0.7 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 ORX66677.1 - 0.43 10.6 19.1 0.035 14.1 12.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 ORX66677.1 - 0.52 10.0 9.5 1 9.0 0.8 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF745) Prominin PF05478.11 ORX66677.1 - 0.69 7.8 12.8 1.1 7.1 12.8 1.4 1 1 0 1 1 1 0 Prominin ERM PF00769.19 ORX66677.1 - 0.78 9.5 17.0 0.059 13.2 11.5 1.9 2 1 0 2 2 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 ORX66677.1 - 1 9.8 15.8 1.1 9.7 12.7 2.4 1 1 1 2 2 2 0 Fez1 DHR10 PF18595.1 ORX66677.1 - 1 9.5 16.7 0.52 10.4 1.1 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 ORX66677.1 - 1.2 9.8 10.1 0.79 10.3 1.4 3.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DUF948 PF06103.11 ORX66677.1 - 1.3 9.3 7.0 1.5 9.1 0.1 3.0 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 ORX66677.1 - 1.5 8.8 12.9 0.51 10.4 3.7 3.2 1 1 1 3 3 3 0 Laminin Domain II LMBR1 PF04791.16 ORX66677.1 - 1.8 7.4 7.9 2.3 7.0 7.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 ORX66677.1 - 2.1 7.5 8.9 1.6 7.9 6.8 2.0 1 1 0 1 1 1 0 TMPIT-like protein Fzo_mitofusin PF04799.13 ORX66677.1 - 2.4 7.7 8.4 2.1 7.9 0.5 2.7 1 1 0 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 ORX66677.1 - 3.9 7.7 17.9 27 4.9 7.9 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family LPP PF04728.13 ORX66677.1 - 4.7 7.7 6.4 3.6 8.0 0.1 3.6 3 1 1 4 4 4 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 ORX66677.1 - 8.8 6.4 23.3 1.2 9.2 11.0 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Complex1_30kDa PF00329.19 ORX66678.1 - 1.8e-46 157.7 0.0 2.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Ribosomal_L31 PF01197.18 ORX66679.1 - 3.1e-05 24.1 0.2 0.00014 22.0 0.2 2.2 1 1 0 1 1 1 1 Ribosomal protein L31 Sec10 PF07393.11 ORX66680.1 - 5.5e-114 382.1 0.0 4e-83 280.1 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 F-box PF00646.33 ORX66680.1 - 2.1e-05 24.2 0.5 4.7e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX66680.1 - 3.5e-05 23.6 0.5 7.7e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like Transthyretin PF00576.21 ORX66681.1 - 2.2e-39 134.5 0.1 2.5e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MRP-S25 PF13741.6 ORX66682.1 - 1.1e-46 159.2 9.4 1.4e-46 159.0 9.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ORX66682.1 - 0.12 12.6 6.3 0.12 12.7 2.8 2.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 DUF5435 PF17503.2 ORX66683.1 - 0.0029 17.4 0.4 0.0045 16.7 0.4 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5435) C1_4 PF07975.12 ORX66683.1 - 0.044 14.0 0.5 0.12 12.6 0.5 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Cgr1 PF03879.14 ORX66684.1 - 1.1e-06 28.9 3.8 1.3e-06 28.7 3.8 1.1 1 0 0 1 1 1 1 Cgr1 family Cyclin PF08613.11 ORX66689.1 - 9.1e-12 45.6 0.0 2.8e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Cyclin GNT-I PF03071.15 ORX66690.1 - 6.2e-08 31.8 0.0 8.2e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 ORX66690.1 - 5.1e-07 29.1 0.0 7.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 ORX66690.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORX66690.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NUC153 PF08159.12 ORX66990.1 - 0.22 11.4 7.1 0.65 9.9 0.1 3.5 3 0 0 3 3 3 0 NUC153 domain DDHD PF02862.17 ORX66990.1 - 0.43 10.7 13.5 0.92 9.6 0.7 2.3 2 0 0 2 2 2 0 DDHD domain Pkinase PF00069.25 ORX66991.1 - 4.1e-52 177.2 0.0 5.7e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX66991.1 - 1.4e-23 83.5 0.0 2.2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX66991.1 - 9.3e-05 22.5 0.2 0.0002 21.4 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX66991.1 - 0.0018 17.9 0.1 0.92 9.1 0.1 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX66991.1 - 0.02 13.9 0.1 0.033 13.1 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORX66991.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX66991.1 - 0.17 11.2 0.1 0.25 10.6 0.1 1.5 1 1 0 1 1 1 0 Kinase-like SR-25 PF10500.9 ORX66991.1 - 1.4 8.4 5.4 0.91 9.1 3.8 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_zinc_N PF00107.26 ORX66992.1 - 1.4e-21 76.8 0.0 2.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORX66992.1 - 1.4e-15 57.1 0.1 2.9e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX66992.1 - 5.6e-07 30.7 0.0 1.6e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase lci PF12197.8 ORX66992.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein ADH_zinc_N PF00107.26 ORX66993.1 - 3.7e-21 75.4 0.0 5.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORX66993.1 - 9.6e-16 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX66993.1 - 2.7e-07 31.7 0.0 7.6e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Adhesin_P1_N PF18652.1 ORX66993.1 - 0.15 12.1 0.1 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain ADH_zinc_N PF00107.26 ORX66994.1 - 3.7e-21 75.4 0.0 5.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORX66994.1 - 9.6e-16 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX66994.1 - 2.7e-07 31.7 0.0 7.6e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Adhesin_P1_N PF18652.1 ORX66994.1 - 0.15 12.1 0.1 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Mito_carr PF00153.27 ORX66995.1 - 4.9e-65 215.5 0.9 1.3e-21 76.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX66995.1 - 0.067 12.3 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease ADH_N PF08240.12 ORX67001.1 - 1.8e-25 89.0 6.7 2.9e-25 88.3 6.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX67001.1 - 3.4e-20 72.3 0.0 7.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX67001.1 - 8.3e-05 23.7 0.0 0.00015 22.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX67001.1 - 0.0043 16.4 0.2 0.0069 15.7 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 ORX67001.1 - 0.0092 16.8 0.1 0.12 13.2 0.1 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Corona_I PF03187.14 ORX67001.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein 2-Hacid_dh_C PF02826.19 ORX67001.1 - 0.091 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YkuD PF03734.14 ORX67010.1 - 1.3 9.4 6.2 5.6 7.4 6.2 1.9 1 1 0 1 1 1 0 L,D-transpeptidase catalytic domain TruD PF01142.18 ORX67011.1 - 2.4e-84 283.6 0.0 4e-81 273.0 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) CH PF00307.31 ORX67012.1 - 1.4e-40 137.8 1.4 1.2e-21 76.9 0.8 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORX67012.1 - 1.2e-05 25.1 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain DUF1942 PF09167.11 ORX67012.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Glyco_hydro_61 PF03443.14 ORX67350.1 - 0.002 18.1 0.0 0.26 11.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX67350.1 - 0.0036 18.0 1.2 0.023 15.4 1.2 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GPI-anchored PF10342.9 ORX67350.1 - 0.13 13.0 0.0 0.24 12.2 0.0 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_16 PF00722.21 ORX67351.1 - 3.5e-18 65.7 0.2 5e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 ORX67352.1 - 1.7e-16 60.2 0.2 1.7e-16 60.2 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Eapp_C PF10238.9 ORX67352.1 - 0.93 9.6 4.5 1.8 8.6 4.5 1.4 1 1 0 1 1 1 0 E2F-associated phosphoprotein Calreticulin PF00262.18 ORX67353.1 - 0.0001 21.3 6.8 0.028 13.3 1.5 2.3 1 1 1 2 2 2 2 Calreticulin family Colipase-like PF15083.6 ORX67353.1 - 0.46 10.6 11.0 2.8 8.1 1.6 3.0 1 1 1 2 2 2 0 Colipase-like Zn_clus PF00172.18 ORX67362.1 - 4.3e-12 45.9 10.5 5.4e-12 45.6 10.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX67363.1 - 1.3e-39 135.8 0.7 1.3e-39 135.8 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX67363.1 - 5e-11 42.5 14.1 1.1e-10 41.5 14.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.18 ORX67372.1 - 1.3e-54 185.4 0.0 1.8e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORX67372.1 - 0.025 14.9 0.0 0.066 13.6 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Aminotran_1_2 PF00155.21 ORX67373.1 - 1.4e-87 294.2 0.0 1.6e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acyltransferase PF01553.21 ORX67374.1 - 5e-10 39.1 0.0 1.1e-08 34.8 0.0 2.6 1 1 0 1 1 1 1 Acyltransferase DUF4220 PF13968.6 ORX67374.1 - 0.0086 15.5 0.8 0.013 14.9 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) PGAP1 PF07819.13 ORX67375.1 - 3.9e-88 295.1 0.0 7.1e-88 294.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORX67375.1 - 6.9e-05 23.6 0.0 0.0012 19.5 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 ORX67375.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ORX67375.1 - 0.0032 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 ORX67375.1 - 0.036 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX67375.1 - 0.079 12.6 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ion_trans PF00520.31 ORX67699.1 - 2.2e-12 46.7 22.7 2.2e-12 46.7 22.7 2.2 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 ORX67699.1 - 0.00045 19.0 19.0 0.0079 14.9 19.0 2.2 1 1 0 1 1 1 1 Polycystin cation channel Zip PF02535.22 ORX67700.1 - 5e-52 177.2 19.3 1.9e-51 175.2 19.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2486 PF10667.9 ORX67701.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF3472 PF11958.8 ORX67702.1 - 1e-18 68.4 1.2 1.5e-18 67.8 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX67702.1 - 6.8e-09 35.9 0.2 1.2e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF4396 PF14342.6 ORX67720.1 - 6.1e-34 117.4 1.4 8.6e-34 116.9 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) SprT-like PF10263.9 ORX67721.1 - 3.8e-27 94.4 1.2 6.9e-27 93.5 1.2 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.19 ORX67721.1 - 0.00015 22.1 1.0 0.00034 21.0 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 ORX67721.1 - 0.0053 17.3 1.0 0.009 16.6 0.1 1.9 2 0 0 2 2 2 1 YABBY protein Zn_ribbon_SprT PF17283.2 ORX67721.1 - 0.02 14.8 2.6 0.046 13.6 2.6 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Tox-MPTase2 PF15638.6 ORX67721.1 - 0.18 11.6 0.4 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Metallopeptidase toxin 2 DUF441 PF04284.13 ORX67722.1 - 0.058 13.4 0.2 0.088 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF441) TB PF00683.17 ORX67722.1 - 0.081 12.7 1.7 0.19 11.5 1.7 1.5 1 0 0 1 1 1 0 TB domain Cation_efflux PF01545.21 ORX67723.1 - 5.3e-49 166.7 16.8 6.4e-49 166.4 16.8 1.1 1 0 0 1 1 1 1 Cation efflux family Anoctamin PF04547.12 ORX67723.1 - 0.63 8.8 3.2 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel Pkinase PF00069.25 ORX67724.1 - 5.1e-73 245.7 0.0 6.4e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX67724.1 - 2.5e-38 131.8 0.0 3.4e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORX67724.1 - 1.6e-15 57.2 1.8 2.5e-15 56.6 0.1 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 ORX67724.1 - 1.6e-06 27.6 0.0 0.00029 20.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 ORX67724.1 - 3.7e-06 26.4 0.1 5.7e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX67724.1 - 1e-05 24.5 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 ORX67724.1 - 0.00013 22.2 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 ORX67724.1 - 0.0018 17.3 0.1 0.0044 16.0 0.3 1.6 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 ORX67724.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORX67724.1 - 0.091 12.7 0.0 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PMI_typeI PF01238.21 ORX67725.1 - 1.1e-124 416.5 0.0 1.2e-124 416.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 ORX67725.1 - 9.9e-08 32.0 0.1 0.0003 20.7 0.0 2.9 3 1 0 3 3 3 2 AraC-like ligand binding domain Cupin_2 PF07883.11 ORX67725.1 - 0.00016 21.3 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain DUF2322 PF10084.9 ORX67725.1 - 0.0037 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2322) AraC_N PF06719.13 ORX67725.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Cupin_6 PF12852.7 ORX67725.1 - 0.15 11.8 0.0 2.4 7.8 0.0 2.8 4 0 0 4 4 4 0 Cupin EF-hand_1 PF00036.32 ORX67726.1 - 2.5e-38 126.7 12.6 5.8e-10 38.0 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORX67726.1 - 9.3e-31 103.1 9.4 2.6e-09 36.3 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 ORX67726.1 - 1.6e-29 102.1 3.1 4.5e-18 65.5 0.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORX67726.1 - 7.5e-26 88.4 10.1 2.1e-06 26.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORX67726.1 - 5.7e-24 83.7 11.0 3.2e-14 52.5 0.3 4.2 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 ORX67726.1 - 3.9e-09 36.7 0.0 0.00032 21.0 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORX67726.1 - 1.2e-08 34.8 3.0 1.1e-05 25.3 0.1 3.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORX67726.1 - 2.4e-07 31.1 0.1 8.3e-05 22.9 0.0 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ORX67726.1 - 9.1e-07 29.0 2.0 0.00052 20.1 0.1 3.3 1 1 3 4 4 4 2 Dockerin type I domain Caleosin PF05042.13 ORX67726.1 - 0.0015 18.5 0.3 1.4 8.8 0.0 2.9 1 1 1 3 3 3 2 Caleosin related protein EFhand_Ca_insen PF08726.10 ORX67726.1 - 0.01 15.9 0.4 0.043 13.9 0.1 2.2 2 1 1 3 3 3 1 Ca2+ insensitive EF hand GPHH PF16905.5 ORX67726.1 - 0.024 14.4 0.0 8.9 6.2 0.0 2.9 2 1 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated UPF0154 PF03672.13 ORX67726.1 - 0.028 14.4 2.1 0.35 10.9 0.0 3.1 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF4497 PF14924.6 ORX67726.1 - 0.049 14.1 0.0 15 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) DUF1521 PF07481.11 ORX67726.1 - 0.099 12.6 0.9 0.43 10.6 0.1 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1521) Beta-lactamase2 PF13354.6 ORX67726.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 1 1 2 2 2 0 Beta-lactamase enzyme family MotA_activ PF09114.10 ORX67726.1 - 0.12 12.6 0.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain PMBR PF09373.10 ORX67726.1 - 0.12 12.5 0.0 64 4.0 0.0 3.5 3 0 0 3 3 3 0 Pseudomurein-binding repeat tRNA-synt_1b PF00579.25 ORX67727.1 - 2.3e-29 102.7 0.0 2.9e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NAD_binding_10 PF13460.6 ORX68059.1 - 3e-14 53.3 0.0 4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX68059.1 - 8.9e-11 41.8 0.0 1.8e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORX68059.1 - 0.0091 15.5 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX68059.1 - 0.049 12.7 0.0 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX68059.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Formyl_trans_N PF00551.19 ORX68059.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase Thioredoxin_8 PF13905.6 ORX68060.1 - 7.8e-15 55.0 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 ORX68060.1 - 0.0054 16.7 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin MWFE PF15879.5 ORX68061.1 - 1.1e-19 70.3 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ACT_7 PF13840.6 ORX68062.1 - 6.6e-19 67.5 0.0 1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ORX68062.1 - 0.011 15.5 0.4 0.047 13.5 0.1 2.2 2 1 0 2 2 2 0 ACT domain DEAD PF00270.29 ORX68063.1 - 1.6e-49 168.0 0.0 3.8e-49 166.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX68063.1 - 5.8e-32 110.3 0.1 2.3e-29 102.0 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 ORX68063.1 - 0.0059 15.4 0.1 0.063 12.0 0.0 2.4 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SOBP PF15279.6 ORX68063.1 - 0.011 16.4 2.6 0.017 15.7 2.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_22 PF13401.6 ORX68063.1 - 0.12 12.7 1.7 1.7 8.9 0.4 3.0 1 1 1 2 2 2 0 AAA domain CDC45 PF02724.14 ORX68063.1 - 0.86 7.8 11.3 1.3 7.3 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CMS1 PF14617.6 ORX68063.1 - 1.5 8.1 0.0 1.5 8.1 0.0 2.9 2 1 0 2 2 1 0 U3-containing 90S pre-ribosomal complex subunit NARP1 PF12569.8 ORX68063.1 - 3 6.6 22.3 5.6 5.8 22.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.13 ORX68063.1 - 3.9 6.2 11.5 7.3 5.3 11.5 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 ORX68063.1 - 4.8 6.6 13.6 9.3 5.7 13.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 ORX68063.1 - 7.1 5.8 5.5 11 5.1 5.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 ORX68063.1 - 9.3 6.4 13.1 17 5.6 13.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 ORX68063.1 - 9.5 6.5 28.4 0.63 10.4 23.0 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Bystin PF05291.11 ORX68064.1 - 1.2e-140 467.8 0.1 1.2e-140 467.8 0.1 1.4 2 0 0 2 2 2 1 Bystin Cwf_Cwc_15 PF04889.12 ORX68064.1 - 3.9 7.1 20.6 5.7 6.6 20.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Forkhead PF00250.18 ORX68072.1 - 2.4e-39 133.5 0.2 2.7e-39 133.3 0.2 1.0 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 ORX68072.1 - 0.07 13.5 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family MMR_HSR1 PF01926.23 ORX68089.1 - 0.00031 20.8 0.5 0.0029 17.7 0.5 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 ORX68089.1 - 0.0019 18.3 0.2 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 ORX68089.1 - 0.011 15.8 0.2 0.32 11.1 0.0 2.4 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 ORX68089.1 - 0.032 14.1 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase GH43_C2 PF17851.1 ORX68870.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain YAF2_RYBP PF17219.3 ORX68871.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif Bac_globin PF01152.21 ORX68885.1 - 3.9e-10 39.9 0.1 5e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX68885.1 - 0.0027 17.6 0.1 0.0045 16.9 0.1 1.4 1 1 0 1 1 1 1 Protoglobin Peptidase_M16_C PF05193.21 ORX68885.1 - 0.028 14.5 0.0 0.14 12.1 0.0 1.8 1 1 1 2 2 2 0 Peptidase M16 inactive domain MIP PF00230.20 ORX68886.1 - 2e-37 129.1 7.1 2.5e-37 128.8 7.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein cobW PF02492.19 ORX68887.1 - 9.9e-46 155.5 0.2 1.4e-45 155.0 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ORX68887.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 ORX68887.1 - 0.021 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 ORX68887.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 ORX68887.1 - 0.041 13.8 0.6 6.4 6.7 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_11 PF13086.6 ORX68887.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORX68887.1 - 0.29 11.6 5.6 2.3 8.6 0.7 2.2 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 ORX68888.1 - 7.5e-24 83.9 1.2 9.2e-24 83.7 1.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX68888.1 - 1.1e-11 45.1 0.8 1.5e-11 44.7 0.8 1.2 1 0 0 1 1 1 1 HMG-box domain KORA PF16509.5 ORX68888.1 - 0.051 13.9 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Sugar_tr PF00083.24 ORX69324.1 - 1.1e-58 199.2 20.6 1.4e-58 198.9 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX69324.1 - 4e-28 98.4 20.0 7.2e-28 97.5 18.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX69324.1 - 4.3e-07 29.5 2.7 8.8e-07 28.5 2.7 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORX69325.1 - 1.1e-58 199.2 20.6 1.4e-58 198.9 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX69325.1 - 4e-28 98.4 20.0 7.2e-28 97.5 18.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX69325.1 - 4.3e-07 29.5 2.7 8.8e-07 28.5 2.7 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Acetyltransf_13 PF13880.6 ORX69326.1 - 2.7e-28 97.7 0.0 4.6e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 ORX69326.1 - 3.6e-05 23.5 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 ORX69326.1 - 0.0012 19.3 0.0 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX69326.1 - 0.012 15.8 0.0 0.045 14.0 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family zinc_ribbon_4 PF13717.6 ORX69326.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DUF2623 PF11115.8 ORX69326.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) zf-Tim10_DDP PF02953.15 ORX69327.1 - 1.3e-21 76.0 0.3 1.6e-21 75.7 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Catalase-rel PF06628.12 ORX69327.1 - 0.041 14.1 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 Catalase-related immune-responsive Peptidase_S10 PF00450.22 ORX69328.1 - 3.2e-91 306.8 0.7 5.1e-91 306.2 0.7 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase RGS PF00615.19 ORX69329.1 - 8.6e-14 51.8 4.3 1.2e-13 51.4 4.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX69329.1 - 9e-06 25.6 21.8 2.2e-05 24.3 20.6 2.2 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ECSCR PF15820.5 ORX69329.1 - 2.4 8.0 5.2 1.9 8.4 1.3 2.5 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator SRP9-21 PF05486.12 ORX69330.1 - 6.9e-11 42.4 2.3 2.8e-09 37.3 2.3 2.1 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Peptidase_M13 PF01431.21 ORX69818.1 - 1.4e-58 197.9 0.0 2.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 ORX69818.1 - 1.2e-51 176.6 1.6 9.8e-40 137.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 IL11 PF07400.11 ORX69818.1 - 0.0083 15.8 0.6 0.04 13.6 0.1 2.3 2 0 0 2 2 2 1 Interleukin 11 G-alpha PF00503.20 ORX69819.1 - 5.4e-121 404.1 5.0 6.2e-121 403.9 5.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX69819.1 - 5.7e-16 58.4 2.0 4e-11 42.7 0.2 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX69819.1 - 0.00076 18.9 6.2 0.0024 17.2 0.1 2.8 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 ORX69819.1 - 0.0023 17.7 0.1 0.0079 16.0 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Rad17 PF03215.15 ORX69819.1 - 0.052 13.5 0.3 0.12 12.2 0.3 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 ORX69819.1 - 0.055 13.6 0.4 2.6 8.2 0.0 2.5 1 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX69819.1 - 0.06 13.1 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORX69819.1 - 0.064 13.5 0.4 8.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORX69819.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MRNIP PF15749.5 ORX69820.1 - 9.7e-18 64.9 33.4 1.7e-17 64.1 23.5 3.8 2 1 1 3 3 3 1 MRN-interacting protein TAF4 PF05236.14 ORX69820.1 - 0.51 10.0 13.4 4.3 7.0 13.0 2.1 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CBM_19 PF03427.13 ORX69839.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) DUF2076 PF09849.9 ORX69841.1 - 2.9 7.8 4.0 3.2 7.7 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PTR2 PF00854.21 ORX69842.1 - 1.4e-80 271.1 9.6 2.1e-80 270.5 9.6 1.2 1 0 0 1 1 1 1 POT family PTR2 PF00854.21 ORX69843.1 - 4.2e-82 276.1 8.2 6.1e-82 275.6 8.2 1.2 1 0 0 1 1 1 1 POT family Baculo_gp41 PF04700.12 ORX69843.1 - 0.2 11.4 0.2 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region SUR7 PF06687.12 ORX69843.1 - 0.73 9.4 8.5 1.6 8.3 3.5 2.4 2 0 0 2 2 2 0 SUR7/PalI family PTR2 PF00854.21 ORX69844.1 - 2.8e-82 276.7 9.2 4.4e-82 276.0 9.2 1.2 1 0 0 1 1 1 1 POT family DUF3980 PF13140.6 ORX69844.1 - 0.79 10.2 4.7 0.21 12.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Sugar_tr PF00083.24 ORX70380.1 - 2.2e-99 333.4 24.8 2.9e-99 333.0 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX70380.1 - 1.4e-34 119.6 24.1 1.4e-34 119.6 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3054 PF11255.8 ORX70380.1 - 5.1 7.7 16.7 0.11 13.0 8.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3054) RTA1 PF04479.13 ORX70381.1 - 2.2e-48 164.6 6.3 2.2e-48 164.6 6.3 1.4 1 1 1 2 2 2 1 RTA1 like protein DUF347 PF03988.12 ORX70381.1 - 0.55 10.5 0.1 0.55 10.5 0.1 3.0 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Asp-Al_Ex PF06826.12 ORX70381.1 - 2.7 7.8 11.0 0.14 11.9 3.8 2.0 1 1 1 2 2 2 0 Predicted Permease Membrane Region p450 PF00067.22 ORX70393.1 - 7.8e-50 170.0 0.2 1.1e-49 169.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP-grasp PF02222.22 ORX70393.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain Adeno_52K PF03052.15 ORX70393.1 - 0.2 11.1 0.5 0.36 10.3 0.1 1.5 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa RIIa PF02197.17 ORX70393.1 - 2.1 8.1 4.4 25 4.6 0.0 3.9 5 0 0 5 5 5 0 Regulatory subunit of type II PKA R-subunit ERG4_ERG24 PF01222.17 ORX70394.1 - 7.3e-128 427.0 13.5 1.5e-127 426.0 13.5 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORX70394.1 - 0.0074 15.8 1.0 0.021 14.4 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2207 PF09972.9 ORX70394.1 - 0.28 9.9 1.2 0.57 8.9 1.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EF_assoc_1 PF08355.12 ORX70394.1 - 1.4 8.6 3.8 0.38 10.4 0.3 1.8 2 0 0 2 2 2 0 EF hand associated 6PGD PF00393.19 ORX70406.1 - 3.7e-129 430.2 0.0 5.1e-129 429.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORX70406.1 - 1.2e-51 175.0 0.1 1.8e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORX70406.1 - 0.05 13.2 0.3 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_11 PF14833.6 ORX70406.1 - 0.092 13.0 0.0 0.85 9.9 0.0 2.5 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORX70406.1 - 0.12 13.0 0.3 0.24 12.0 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 ORX70414.1 - 1.5e-54 185.1 0.0 9.7e-54 182.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX70414.1 - 7.4e-24 84.4 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX70414.1 - 1.9e-06 27.4 0.0 3.8e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX70414.1 - 6.6e-05 22.9 0.2 0.00044 20.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX70414.1 - 0.0033 17.1 1.4 0.027 14.1 0.1 2.4 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX70414.1 - 0.0086 15.1 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX70414.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORX70414.1 - 0.26 10.6 3.0 0.09 12.1 0.3 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_11 PF08241.12 ORX70415.1 - 2.6e-18 66.4 0.0 5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX70415.1 - 4.6e-14 52.9 0.0 8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX70415.1 - 9e-10 38.6 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX70415.1 - 1.3e-08 35.5 0.0 4e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX70415.1 - 6.9e-08 32.4 0.0 1.5e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX70415.1 - 5.1e-05 22.7 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 ORX70415.1 - 0.00022 20.4 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 ORX70415.1 - 0.00063 19.7 0.0 0.0032 17.4 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 ORX70415.1 - 0.0021 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 ORX70415.1 - 0.021 14.4 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain DUF5594 PF18057.1 ORX70415.1 - 0.022 14.6 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5594) Cas9_REC PF16592.5 ORX70415.1 - 0.058 12.1 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 RrnaAD PF00398.20 ORX70415.1 - 0.098 11.7 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 ORX70416.1 - 3.4e-18 66.1 0.0 6.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX70416.1 - 6.8e-14 52.3 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX70416.1 - 1.6e-10 41.1 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX70416.1 - 1.9e-08 34.9 0.0 8.9e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX70416.1 - 1.2e-06 28.4 0.0 3.9e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX70416.1 - 0.00019 20.8 0.0 0.00045 19.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORX70416.1 - 0.0007 19.5 0.0 0.0053 16.6 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 ORX70416.1 - 0.0031 16.7 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase FliL PF03748.14 ORX70416.1 - 0.097 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL MTS PF05175.14 ORX70416.1 - 0.13 11.8 0.0 0.92 9.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Radical_SAM PF04055.21 ORX70417.1 - 6.2e-16 59.2 0.5 2.7e-15 57.1 0.2 2.3 2 1 0 2 2 2 1 Radical SAM superfamily GATA PF00320.27 ORX70425.1 - 9.3e-31 105.1 15.7 4.9e-16 58.0 4.0 2.5 2 0 0 2 2 2 2 GATA zinc finger Vps36-NZF-N PF16988.5 ORX70425.1 - 0.00073 18.9 4.2 0.16 11.4 0.7 3.7 3 1 1 4 4 4 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn-ribbon_8 PF09723.10 ORX70425.1 - 0.0012 18.9 2.4 0.63 10.2 0.2 2.7 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORX70425.1 - 0.0037 16.7 5.0 0.58 9.7 0.5 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding TDP43_N PF18694.1 ORX70425.1 - 0.029 14.2 0.1 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 ORX70425.1 - 0.089 12.8 11.8 3.4 7.8 1.1 3.2 1 1 2 3 3 3 0 Double zinc ribbon NMD3 PF04981.13 ORX70425.1 - 0.094 12.2 1.9 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 NMD3 family Auto_anti-p27 PF06677.12 ORX70425.1 - 0.12 12.5 8.4 1 9.5 1.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ORX70425.1 - 0.36 10.7 4.6 2.5 8.0 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 ORX70425.1 - 0.51 10.8 9.1 0.51 10.8 5.0 2.7 2 1 1 3 3 3 0 Cytochrome c3 OrfB_Zn_ribbon PF07282.11 ORX70425.1 - 0.69 9.9 9.3 4.2 7.4 0.7 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Cytochrome_C7 PF14522.6 ORX70425.1 - 7.3 6.7 8.0 0.28 11.2 1.0 2.2 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Zn_Tnp_IS1595 PF12760.7 ORX70425.1 - 9 6.4 10.5 1.3 9.1 1.0 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Fungal_trans PF04082.18 ORX70426.1 - 2.5e-09 36.6 0.1 4.1e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX70426.1 - 9.4e-07 28.9 9.8 1.8e-06 28.0 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serinc PF03348.15 ORX71016.1 - 0.00041 19.4 3.4 0.00046 19.2 3.4 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) CBFB_NFYA PF02045.15 ORX71017.1 - 6.1e-29 100.4 11.4 1e-28 99.7 11.4 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_L19e PF01280.20 ORX71018.1 - 8.5e-65 217.2 10.4 8.5e-65 217.2 10.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L19e bZIP_1 PF00170.21 ORX71019.1 - 4.9e-11 42.6 12.9 9.2e-11 41.7 12.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX71019.1 - 0.04 14.0 16.9 0.28 11.3 16.9 2.1 1 1 0 1 1 1 0 Basic region leucine zipper SHE3 PF17078.5 ORX71019.1 - 0.14 11.8 4.0 0.21 11.3 4.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 AAA_17 PF13207.6 ORX71019.1 - 0.16 12.4 0.2 0.26 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain bZIP_Maf PF03131.17 ORX71019.1 - 0.16 12.5 8.3 0.31 11.6 8.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 ORX71019.1 - 0.31 11.7 1.7 0.6 10.8 1.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ADIP PF11559.8 ORX71019.1 - 0.34 11.0 6.9 0.54 10.3 6.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LIAS_N PF16881.5 ORX71020.1 - 4.3e-20 72.1 0.3 1e-19 70.9 0.2 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ORX71020.1 - 8.7e-13 49.0 0.1 4e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily HLH PF00010.26 ORX71021.1 - 6.8e-12 45.2 0.4 1.5e-11 44.0 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Spc19 PF08287.11 ORX71021.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.3 2 0 0 2 2 2 0 Spc19 MFS_1 PF07690.16 ORX71022.1 - 3.4e-54 184.1 20.5 3.4e-54 184.1 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX71022.1 - 1.8e-08 33.7 10.5 1.8e-08 33.7 10.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DEAD PF00270.29 ORX71024.1 - 5.5e-24 84.9 0.1 9.5e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX71024.1 - 1.9e-21 76.5 0.1 4.7e-20 72.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 ORX71024.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 ORX71024.1 - 0.0055 16.7 0.1 0.0088 16.1 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1962 PF09227.10 ORX71049.1 - 1.1 9.7 13.5 0.41 11.0 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) FAD_binding_4 PF01565.23 ORX71050.1 - 1.3e-30 106.0 2.0 2.1e-30 105.3 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX71050.1 - 5.8e-15 55.1 0.9 1.2e-14 54.1 0.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like CorA PF01544.18 ORX71051.1 - 2.8e-46 158.2 0.1 3.6e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cas9_b_hairpin PF17893.1 ORX71051.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain DUF1367 PF07105.11 ORX71051.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1367) Fungal_trans PF04082.18 ORX71052.1 - 0.013 14.6 1.3 0.018 14.1 1.3 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain LRR_6 PF13516.6 ORX71054.1 - 1.4e-08 34.1 9.6 0.06 13.4 1.0 5.6 6 0 0 6 6 6 4 Leucine Rich repeat F-box-like PF12937.7 ORX71054.1 - 3.4e-07 30.1 0.3 2.3e-06 27.4 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORX71054.1 - 7.2e-07 29.4 7.8 0.82 10.2 0.4 5.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) MiAMP1 PF09117.10 ORX71054.1 - 0.031 14.5 1.3 2.2 8.6 0.4 2.9 1 1 1 2 2 2 0 MiAMP1 F-box PF00646.33 ORX71054.1 - 0.035 14.0 0.2 0.17 11.8 0.2 2.3 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 ORX71054.1 - 0.82 10.5 8.4 15 6.6 0.6 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 ORX71054.1 - 3.6 7.9 6.5 13 6.1 0.5 4.1 4 1 1 5 5 5 0 Ste50p, sterile alpha motif Cyclin PF08613.11 ORX71055.1 - 1.4e-11 45.0 0.0 2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin ER_lumen_recept PF00810.18 ORX71055.1 - 0.0013 19.5 0.9 0.007 17.2 0.3 1.9 1 1 1 2 2 2 1 ER lumen protein retaining receptor Cyclin_N PF00134.23 ORX71055.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DJ-1_PfpI PF01965.24 ORX71689.1 - 7.3e-09 35.6 0.0 2.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX71689.1 - 0.0016 18.2 0.1 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX71689.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain Carb_anhydrase PF00194.21 ORX71698.1 - 2e-44 152.1 1.0 2.9e-44 151.5 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MFS_1 PF07690.16 ORX71699.1 - 1.5e-51 175.4 48.8 1.5e-51 175.4 48.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX71699.1 - 3.6e-16 58.7 24.8 5e-16 58.3 24.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX71699.1 - 2.4e-13 49.8 13.0 2.4e-13 49.8 13.0 3.6 2 1 1 4 4 4 1 Sugar (and other) transporter GST_N_3 PF13417.6 ORX71700.1 - 1.9e-10 41.0 0.1 4.8e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX71700.1 - 0.00049 20.3 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORX71700.1 - 0.049 14.0 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX71700.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OPT PF03169.15 ORX71701.1 - 3.5e-133 445.5 32.4 4e-133 445.3 32.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1772 PF08592.11 ORX71701.1 - 0.0045 17.3 7.8 0.025 14.9 0.2 3.9 2 1 2 4 4 4 2 Domain of unknown function (DUF1772) Fringe PF02434.16 ORX71702.1 - 1.7e-07 30.9 2.0 7.5e-06 25.6 2.1 2.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 ORX71702.1 - 6.6e-05 22.8 0.1 0.00061 19.7 0.0 2.2 1 1 1 2 2 2 1 Galactosyltransferase Phtf-FEM1B_bdg PF12129.8 ORX71702.1 - 0.007 16.2 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Ferlin_C PF16165.5 ORX71702.1 - 0.019 14.9 0.2 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Ferlin C-terminus GST_N_3 PF13417.6 ORX71718.1 - 1.6e-13 50.8 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX71718.1 - 3.8e-12 46.3 0.1 1.1e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORX71718.1 - 2.5e-10 40.5 0.0 5.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX71718.1 - 6.1e-09 36.0 0.0 1.4e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX71718.1 - 6.1e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX71718.1 - 2.8e-06 27.5 0.0 1.1e-05 25.5 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX71718.1 - 2.7e-05 24.7 0.0 0.00049 20.7 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORX71718.1 - 0.0024 17.7 0.2 0.009 15.8 0.1 2.1 2 1 0 2 2 2 1 Glutaredoxin 2, C terminal domain Tcp10_C PF07202.13 ORX71718.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus TusA PF01206.17 ORX71719.1 - 2.7e-18 65.6 0.1 3.8e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Sulfurtransferase TusA Rhodanese PF00581.20 ORX71719.1 - 0.00019 21.9 0.0 0.00054 20.4 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain DJ-1_PfpI PF01965.24 ORX71720.1 - 3e-05 23.9 0.0 7.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_6 PF12697.7 ORX71721.1 - 2.1e-06 28.5 0.0 2.5e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX71721.1 - 0.014 14.7 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4385 PF14328.6 ORX71722.1 - 6.5e-66 220.9 0.5 7.4e-66 220.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) VirE PF05272.11 ORX71722.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E ABC2_membrane PF01061.24 ORX71724.1 - 2.3e-46 157.9 19.4 3.3e-46 157.4 19.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORX71724.1 - 1.7e-23 83.6 0.0 4e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORX71724.1 - 8.8e-05 22.4 0.1 0.063 13.1 0.4 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORX71724.1 - 0.00011 21.4 21.3 0.00011 21.4 21.3 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 ORX71724.1 - 0.00025 20.6 0.3 0.66 9.4 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX71724.1 - 0.00074 19.5 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ORX71724.1 - 0.00076 20.0 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX71724.1 - 0.00099 19.5 0.1 0.003 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ORX71724.1 - 0.0059 16.2 0.1 0.015 14.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX71724.1 - 0.11 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORX71724.1 - 0.14 11.9 2.1 0.2 11.4 0.6 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 ORX71724.1 - 0.14 12.0 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 NACHT domain AAA_35 PF14516.6 ORX71724.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 ORX71724.1 - 0.22 11.8 0.5 1.3 9.3 0.4 2.3 3 0 0 3 3 3 0 AAA domain ABC2_membrane_2 PF12679.7 ORX71724.1 - 0.38 10.0 13.3 0.26 10.5 9.6 2.3 2 1 2 4 4 4 0 ABC-2 family transporter protein Pkinase PF00069.25 ORX71725.1 - 1.6e-25 90.0 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX71725.1 - 4.3e-12 45.9 0.0 5.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX71725.1 - 9.6e-08 31.2 0.1 1.4e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX71725.1 - 0.0026 17.7 0.0 0.69 9.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Zn_Tnp_IS1595 PF12760.7 ORX71739.1 - 0.036 14.0 2.6 0.073 13.1 2.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 ORX71739.1 - 0.12 12.1 5.7 0.062 13.0 3.1 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 ORX71739.1 - 0.41 10.2 3.4 2 8.0 0.0 2.9 4 0 0 4 4 4 0 TFIIB zinc-binding TipAS PF07739.13 ORX71741.1 - 0.016 15.8 0.1 0.067 13.8 0.0 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Sugar_tr PF00083.24 ORX71758.1 - 2e-101 340.1 27.8 2.4e-101 339.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX71758.1 - 1.8e-28 99.5 27.4 1.8e-28 99.5 27.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 ORX71758.1 - 0.0013 17.6 3.0 0.0066 15.2 3.2 1.8 1 1 1 2 2 2 1 Reduced folate carrier GPI-anchored PF10342.9 ORX71759.1 - 0.065 14.0 0.0 0.092 13.5 0.0 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_61 PF03443.14 ORX71760.1 - 0.001 19.0 0.9 0.0014 18.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX71760.1 - 0.046 14.4 5.6 0.082 13.6 5.6 1.5 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading RRM_1 PF00076.22 ORX71761.1 - 7.4e-36 121.8 0.6 7e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX71761.1 - 7.9e-06 25.9 0.1 0.0006 19.9 0.0 3.2 2 2 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 ORX71761.1 - 0.00087 19.1 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain OB_RNB PF08206.11 ORX71761.1 - 0.089 12.5 0.7 0.96 9.2 0.2 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RGS PF00615.19 ORX71762.1 - 2e-14 53.8 1.7 3.4e-14 53.1 1.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain HET-s_218-289 PF11558.8 ORX72531.1 - 9e-05 22.4 0.9 11 6.1 0.0 5.9 4 2 2 6 6 6 2 Het-s 218-289 UPF0669 PF17065.5 ORX72531.1 - 0.092 12.5 0.0 18 5.1 0.0 3.3 3 1 1 4 4 4 0 Putative cytokine, C6ORF120 HA2 PF04408.23 ORX72531.1 - 0.14 12.5 2.6 3.9 7.8 0.1 3.1 2 1 1 3 3 3 0 Helicase associated domain (HA2) TCR_zetazeta PF11628.8 ORX72585.1 - 0.97 9.2 4.8 13 5.6 0.1 2.9 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain Pkinase PF00069.25 ORX73405.1 - 2.7e-60 204.0 0.0 3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX73405.1 - 7e-30 104.2 0.0 8.3e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX73405.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORX73405.1 - 0.003 17.2 0.8 0.049 13.2 0.0 2.1 1 1 0 2 2 2 1 RIO1 family APH PF01636.23 ORX73405.1 - 0.0091 15.9 0.1 0.024 14.5 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX73405.1 - 0.011 15.4 0.3 0.074 12.7 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX73405.1 - 0.025 13.5 0.4 0.097 11.6 0.1 1.8 1 1 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX73405.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORX73405.1 - 0.057 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORX73405.1 - 0.087 12.4 0.7 0.79 9.3 0.7 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase PIP49_C PF12260.8 ORX73405.1 - 0.19 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF3472 PF11958.8 ORX73419.1 - 0.00013 22.4 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Ntox6 PF15544.6 ORX73419.1 - 0.1 12.2 0.3 2.1 7.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial toxin 6 DUF3472 PF11958.8 ORX73420.1 - 9.5e-08 32.7 1.1 1.6e-07 31.9 1.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX73420.1 - 1.8e-05 24.7 0.3 2.8e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) Myticin-prepro PF10690.9 ORX73421.1 - 0.0018 18.5 0.4 0.0029 17.8 0.4 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Glyco_hydro_18 PF00704.28 ORX73431.1 - 9.7e-12 45.2 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADH_N PF08240.12 ORX73432.1 - 1.8e-25 89.0 6.7 2.9e-25 88.3 6.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX73432.1 - 3.4e-20 72.3 0.0 7.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX73432.1 - 8.3e-05 23.7 0.0 0.00015 22.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX73432.1 - 0.0043 16.4 0.2 0.0069 15.7 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 ORX73432.1 - 0.0092 16.8 0.1 0.12 13.2 0.1 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Corona_I PF03187.14 ORX73432.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein 2-Hacid_dh_C PF02826.19 ORX73432.1 - 0.091 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4179 PF13786.6 ORX73481.1 - 0.17 12.4 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) PTR2 PF00854.21 ORX73509.1 - 1.3e-79 267.9 7.2 1.3e-79 267.9 7.2 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX73509.1 - 9.8e-10 37.9 38.3 1.5e-07 30.7 9.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Asp PF00026.23 ORX73510.1 - 9.9e-42 143.4 6.0 2.5e-29 102.7 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX73510.1 - 1.8e-06 28.3 3.3 2.4e-05 24.7 3.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX73510.1 - 0.013 15.3 0.1 0.28 11.0 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal PTR2 PF00854.21 ORX73511.1 - 7.2e-53 179.8 11.1 1.8e-34 119.2 0.0 3.1 2 1 1 3 3 3 3 POT family MFS_1 PF07690.16 ORX73511.1 - 5.6e-11 42.0 18.7 1.1e-07 31.1 1.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily zf-RING_13 PF17977.1 ORX73533.1 - 3.3e-06 27.1 1.4 0.013 15.6 0.2 2.2 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain Agenet PF05641.12 ORX73533.1 - 0.15 12.5 0.0 17 6.0 0.0 2.2 2 0 0 2 2 2 0 Agenet domain MIP PF00230.20 ORX75061.1 - 1.3e-51 175.5 15.6 1.5e-51 175.3 15.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein dDENN PF03455.19 ORX75061.1 - 0.022 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 dDENN domain bZIP_1 PF00170.21 ORX75062.1 - 0.00076 19.5 14.9 0.00087 19.3 10.2 3.0 2 1 1 3 3 3 1 bZIP transcription factor ThiS PF02597.20 ORX75109.1 - 2.8e-14 53.5 0.0 3.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ThiS family Metallophos PF00149.28 ORX75110.1 - 0.054 14.0 0.1 0.059 13.9 0.1 1.0 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase UNC45-central PF11701.8 ORX75111.1 - 4.6e-31 107.9 8.5 1.4e-27 96.5 0.6 4.8 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.23 ORX75111.1 - 7.1e-12 44.9 1.0 0.0032 17.5 0.0 7.7 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORX75111.1 - 1.9e-06 28.2 2.2 1.5 9.2 0.0 6.1 4 1 1 6 6 6 1 HEAT repeats DNA_alkylation PF08713.11 ORX75111.1 - 0.0055 16.4 1.7 0.29 10.8 0.1 3.2 2 1 1 3 3 3 1 DNA alkylation repair enzyme HEAT PF02985.22 ORX75111.1 - 0.067 13.5 3.6 23 5.6 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat CHASE6_C PF17150.4 ORX75111.1 - 0.3 11.8 1.9 1.3 9.8 0.4 2.6 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain RecQ_Zn_bind PF16124.5 ORX75111.1 - 0.41 11.4 3.0 2.5 8.9 0.5 3.7 3 1 0 3 3 3 0 RecQ zinc-binding RasGEF_N_2 PF14663.6 ORX75111.1 - 2.5 8.5 5.8 9.3 6.7 0.2 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Helicase_PWI PF18149.1 ORX75112.1 - 6.6e-41 139.0 0.7 6.6e-41 139.0 0.7 2.9 3 0 0 3 3 3 1 N-terminal helicase PWI domain DEAD PF00270.29 ORX75112.1 - 2.2e-17 63.4 0.2 5.9e-17 62.0 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORX75112.1 - 1.3e-08 35.1 0.6 1.6e-07 31.5 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX75112.1 - 5.2e-06 26.8 0.1 0.00011 22.5 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CopB PF05275.11 ORX75112.1 - 0.018 14.7 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) TFIIA PF03153.13 ORX75112.1 - 3.9 7.4 11.0 7.6 6.4 11.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.23 ORX75125.1 - 3.8e-28 98.2 0.7 5.3e-28 97.8 0.7 1.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORX75125.1 - 0.0011 19.0 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HLH PF00010.26 ORX75143.1 - 1.9e-13 50.1 0.8 3.6e-13 49.2 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ABC2_membrane PF01061.24 ORX75152.1 - 3.9e-77 258.4 53.5 2.1e-46 158.0 16.8 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORX75152.1 - 2.2e-35 122.1 0.0 6.3e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORX75152.1 - 1.2e-32 111.6 3.3 1e-23 83.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX75152.1 - 4e-13 49.8 0.0 1.1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 ORX75152.1 - 8.9e-06 25.7 0.2 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ORX75152.1 - 1.5e-05 25.0 0.0 0.069 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORX75152.1 - 5e-05 22.6 13.6 5e-05 22.6 13.6 3.0 4 0 0 4 4 3 2 ABC-2 family transporter protein AAA_29 PF13555.6 ORX75152.1 - 0.00013 21.6 0.0 0.0062 16.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX75152.1 - 0.00014 22.3 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORX75152.1 - 0.00051 20.6 0.0 0.046 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORX75152.1 - 0.00071 19.2 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX75152.1 - 0.014 15.7 0.1 0.61 10.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 ORX75152.1 - 0.018 14.6 0.2 0.076 12.6 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORX75152.1 - 0.023 14.8 0.2 11 6.2 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORX75152.1 - 0.029 14.5 0.0 0.081 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX75152.1 - 0.093 13.0 0.3 0.6 10.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 ORX75152.1 - 0.13 10.8 0.1 0.87 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1398 PF07166.11 ORX75152.1 - 0.15 12.1 0.0 4 7.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1398) AAA_30 PF13604.6 ORX75152.1 - 0.18 11.5 0.1 2.6 7.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORX75152.1 - 0.2 12.1 0.2 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3472 PF11958.8 ORX75153.1 - 4.7e-07 30.4 0.5 1.1e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX75153.1 - 0.0012 18.8 0.1 0.0012 18.8 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF5077) 7TM_GPCR_Srt PF10321.9 ORX75153.1 - 0.13 11.3 1.5 0.18 10.7 1.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Myticin-prepro PF10690.9 ORX75166.1 - 0.0008 19.6 0.4 0.0012 19.0 0.4 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Suppressor_APC PF11414.8 ORX75167.1 - 0.022 14.8 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein HPIH PF13323.6 ORX75168.1 - 0.00046 20.1 0.6 0.0082 16.0 0.0 2.0 1 1 1 2 2 2 2 N-terminal domain with HPIH motif DJ-1_PfpI PF01965.24 ORX75169.1 - 4e-10 39.7 0.0 1.4e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Latrotoxin_C PF15658.6 ORX75169.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain ThiJ_like PF17124.5 ORX75169.1 - 0.034 13.8 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 ThiJ/PfpI family-like Myticin-prepro PF10690.9 ORX75198.1 - 0.0065 16.7 0.3 0.01 16.1 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel MFS_1 PF07690.16 ORX75223.1 - 8.6e-29 100.5 49.6 9.9e-29 100.4 42.1 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX75223.1 - 6.2e-11 41.4 19.8 6.2e-11 41.4 16.3 2.1 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX75223.1 - 0.02 13.8 42.1 0.0081 15.1 6.8 3.6 2 2 1 4 4 4 0 Sugar (and other) transporter DUF3341 PF11821.8 ORX75223.1 - 0.39 10.4 5.4 4.1 7.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3341) GST_N_3 PF13417.6 ORX75224.1 - 1.8e-09 37.8 0.0 5.2e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX75224.1 - 2.4e-08 34.2 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORX75224.1 - 0.0066 16.8 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX75224.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Polysacc_deac_1 PF01522.21 ORX75225.1 - 2.1e-35 121.3 0.1 4.8e-35 120.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX75225.1 - 0.0037 16.5 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF4746 PF15928.5 ORX75225.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PH PF00169.29 ORX75226.1 - 5.4e-13 49.4 0.1 1.4e-09 38.4 0.0 2.7 1 1 0 2 2 2 2 PH domain PH_6 PF15406.6 ORX75226.1 - 2e-10 40.9 0.0 2e-10 40.9 0.0 3.2 3 1 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 ORX75226.1 - 0.046 14.1 2.5 0.13 12.7 0.4 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 ORX75226.1 - 0.053 13.9 0.0 0.22 11.9 0.0 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain NUDIX PF00293.28 ORX75227.1 - 2.5e-26 92.2 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2075 PF09848.9 ORX75227.1 - 0.0082 15.4 0.4 0.33 10.1 0.1 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) MIP PF00230.20 ORX75241.1 - 9.5e-31 107.3 11.2 1.1e-30 107.0 11.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S8 PF00082.22 ORX75242.1 - 6.3e-33 114.3 20.3 1.2e-32 113.4 20.3 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX75242.1 - 0.00011 22.8 0.5 0.0069 17.0 0.2 2.3 1 1 1 2 2 2 2 Peptidase inhibitor I9 NAD_binding_10 PF13460.6 ORX75243.1 - 1.8e-14 54.0 0.1 2.5e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX75243.1 - 4.7e-10 39.4 0.1 7.3e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ORX75243.1 - 4.1e-07 29.3 0.0 0.00031 19.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX75243.1 - 1.6e-06 27.5 0.0 5.5e-06 25.7 0.0 2.0 3 0 0 3 3 3 1 Male sterility protein Epimerase PF01370.21 ORX75243.1 - 1.6e-06 27.7 0.0 4.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORX75243.1 - 0.00046 20.6 0.0 0.00086 19.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX75243.1 - 0.016 15.4 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 ORX75243.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ORX75243.1 - 0.067 13.9 0.1 0.13 13.0 0.1 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TM1506 PF08973.10 ORX75243.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) Lipase_3 PF01764.25 ORX75244.1 - 1.7e-19 70.1 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX75244.1 - 0.0046 17.6 0.0 0.0082 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 ORX75245.1 - 1.7e-19 70.1 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX75245.1 - 0.0059 17.2 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S30 PF04758.14 ORX75246.1 - 5.7e-29 100.1 6.2 6.2e-29 100.0 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF3408 PF11888.8 ORX75246.1 - 0.016 15.4 1.6 0.018 15.2 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Kinesin PF00225.23 ORX75247.1 - 3.2e-103 345.2 0.7 3.5e-103 345.0 0.7 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX75247.1 - 2.5e-22 79.4 1.3 2.6e-22 79.3 0.2 1.6 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 ORX75247.1 - 0.13 12.5 0.0 0.7 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain MttA_Hcf106 PF02416.16 ORX75266.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family PH_12 PF16457.5 ORX75267.1 - 0.056 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain HTH_19 PF12844.7 ORX75267.1 - 0.15 12.1 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TrbM PF07424.11 ORX75268.1 - 0.072 13.0 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 TrbM Cg6151-P PF10233.9 ORX75270.1 - 1e-22 80.6 11.8 1.2e-22 80.3 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P OSTMP1 PF09777.9 ORX75270.1 - 1 8.7 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3040 PF11239.8 ORX75270.1 - 1 9.6 4.8 0.41 10.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF373 PF04123.13 ORX75270.1 - 5.8 6.3 8.0 17 4.7 8.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF778 PF05608.12 ORX75271.1 - 0.0024 18.3 0.0 0.0025 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) TetR_C_10 PF16295.5 ORX75271.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3336 PF11815.8 ORX75289.1 - 6.8e-31 106.8 0.2 1.3e-30 105.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORX75289.1 - 1e-21 78.1 0.0 1.6e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Tom37 PF10568.9 ORX75290.1 - 4.1e-34 117.6 0.3 6e-34 117.1 0.3 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORX75290.1 - 8e-22 76.8 0.0 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORX75290.1 - 8.6e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORX75290.1 - 3.1e-06 27.1 0.1 1.3e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX75290.1 - 0.00027 21.1 0.0 0.0006 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX75290.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1356 PF07092.12 ORX75292.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 ORX75292.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein Linker_histone PF00538.19 ORX75293.1 - 3.1e-29 101.2 0.1 3.1e-29 101.2 0.1 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Aldedh PF00171.22 ORX75294.1 - 1.8e-35 122.4 0.0 2e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OPT PF03169.15 ORX75305.1 - 2.1e-61 208.4 28.3 2.7e-41 142.0 11.0 3.0 2 1 1 3 3 3 3 OPT oligopeptide transporter protein Peptidase_A24 PF01478.18 ORX75305.1 - 0.0099 16.3 0.4 0.0099 16.3 0.4 4.2 4 1 0 4 4 4 1 Type IV leader peptidase family CBAH PF02275.18 ORX75306.1 - 0.015 14.9 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family COG5 PF10392.9 ORX75307.1 - 0.045 13.9 0.3 0.14 12.3 0.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V-ATPase_G PF03179.15 ORX75307.1 - 0.65 10.6 3.6 0.43 11.1 0.5 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Kelch_4 PF13418.6 ORX75308.1 - 0.00057 19.8 0.0 3.2 7.8 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORX75308.1 - 0.007 16.3 1.7 4.7 7.3 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 ORX75308.1 - 0.01 16.1 1.5 13 6.2 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 ORX75308.1 - 0.019 14.9 0.0 12 6.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 ORX75308.1 - 0.068 13.5 4.2 43 4.5 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Oxidored_FMN PF00724.20 ORX75348.1 - 1.1e-95 320.8 0.0 1.3e-95 320.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 ORX75349.1 - 8.6e-59 199.6 24.4 1e-58 199.3 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX75349.1 - 1.4e-27 96.6 27.3 3.7e-27 95.2 25.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX75349.1 - 4.7e-07 29.4 2.8 1e-06 28.3 2.8 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX75349.1 - 6.9e-05 21.6 9.0 6.9e-05 21.6 9.0 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORX75349.1 - 0.0041 16.7 1.1 0.049 13.2 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORX75349.1 - 0.24 9.6 10.8 0.25 9.6 5.1 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family XFP_N PF09364.10 ORX75350.1 - 3.3e-153 509.8 0.1 4.2e-153 509.5 0.1 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 ORX75350.1 - 4.4e-79 264.3 0.0 2.7e-78 261.7 0.0 2.0 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 ORX75350.1 - 8.4e-79 263.7 0.0 1.3e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 ORX75350.1 - 0.0069 16.2 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CDP-OH_P_transf PF01066.21 ORX75351.1 - 8.5e-12 45.7 0.3 8.5e-12 45.7 0.3 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Zn_clus PF00172.18 ORX75374.1 - 1.1e-10 41.5 17.9 1.3e-10 41.2 17.9 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps16_C PF04840.12 ORX75377.1 - 7.8e-81 271.6 5.3 3.4e-76 256.3 4.1 3.3 1 1 1 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 ORX75377.1 - 1.4e-69 234.8 0.0 3.9e-69 233.4 0.0 1.7 2 0 0 2 2 2 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 ORX75377.1 - 0.14 12.5 0.0 0.79 10.1 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Vps16_N PF04841.13 ORX75378.1 - 1e-29 103.6 0.0 1.1e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Vps16, N-terminal region ANAPC4_WD40 PF12894.7 ORX75378.1 - 0.024 14.9 0.1 0.067 13.5 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 ORX75379.1 - 4.9e-64 212.3 2.5 3.2e-23 81.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX75379.1 - 0.14 11.3 0.2 8.1 5.5 0.0 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease YAF2_RYBP PF17219.3 ORX75396.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif YAF2_RYBP PF17219.3 ORX75397.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif YAF2_RYBP PF17219.3 ORX75398.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif GT-D PF08759.11 ORX75408.1 - 0.15 11.7 0.0 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold SPRY PF00622.28 ORX75419.1 - 2e-21 76.3 0.8 2.9e-21 75.8 0.2 1.6 2 0 0 2 2 2 1 SPRY domain Tfb2 PF03849.14 ORX75420.1 - 4.9e-146 486.3 3.5 5.8e-146 486.0 3.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ORX75420.1 - 4e-26 91.2 0.6 1.1e-25 89.9 0.6 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ORX75420.1 - 0.00054 20.1 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Rad21_Rec8_N PF04825.13 ORX75437.1 - 2.2e-38 130.8 0.0 4e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORX75437.1 - 3.1e-15 55.2 0.4 1e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 ORX75437.1 - 0.02 14.8 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 Segregation and condensation protein ScpA NAC PF01849.18 ORX75438.1 - 1.1e-22 79.7 0.4 2e-22 78.9 0.4 1.4 1 0 0 1 1 1 1 NAC domain Peptidase_C39 PF03412.15 ORX75438.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family Cmc1 PF08583.10 ORX75439.1 - 1.4e-12 47.5 0.8 2.1e-12 46.9 0.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 ORX75439.1 - 0.066 13.5 0.6 0.69 10.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.12 ORX75439.1 - 0.078 12.8 0.9 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 PAN-like domain Atg31 PF09795.9 ORX75440.1 - 0.0043 17.1 0.9 0.0084 16.1 0.9 1.5 1 1 0 1 1 1 1 Autophagy-related protein 31 FAS_meander PF17951.1 ORX75440.1 - 0.036 13.9 0.2 0.048 13.5 0.2 1.1 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Mo25 PF08569.11 ORX75441.1 - 1.8e-110 369.4 6.1 2e-110 369.2 6.1 1.0 1 0 0 1 1 1 1 Mo25-like Ribosomal_L24e PF01246.20 ORX75442.1 - 4.2e-33 113.4 0.3 4.2e-33 113.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CDPS PF16715.5 ORX75442.1 - 0.43 10.2 5.7 0.62 9.7 5.7 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase DDHD PF02862.17 ORX75442.1 - 1.5 9.0 5.0 1.8 8.6 5.0 1.0 1 0 0 1 1 1 0 DDHD domain Glyco_hydro_18 PF00704.28 ORX75452.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SF3b1 PF08920.10 ORX75453.1 - 4.6e-44 149.7 6.4 4.6e-44 149.7 6.4 3.1 2 1 1 3 3 2 2 Splicing factor 3B subunit 1 HEAT PF02985.22 ORX75453.1 - 4.9e-11 41.9 7.9 0.14 12.5 0.1 9.3 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 ORX75453.1 - 6.8e-11 42.4 7.8 0.015 15.7 0.1 8.5 6 3 3 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 ORX75453.1 - 6.1e-09 36.2 6.8 0.55 10.8 0.0 7.6 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORX75453.1 - 3.3e-06 27.6 2.0 0.14 12.8 0.0 5.0 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORX75453.1 - 7.4e-05 21.5 5.6 0.044 12.3 0.1 3.3 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 ORX75453.1 - 0.00027 21.0 8.7 2.7 8.0 0.0 5.9 6 3 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORX75453.1 - 0.0021 17.7 1.8 2.2 7.8 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal NUC173 PF08161.12 ORX75453.1 - 0.0029 17.3 1.1 4 7.0 0.0 4.7 3 1 1 4 4 4 1 NUC173 domain Dopey_N PF04118.14 ORX75453.1 - 0.0058 15.8 2.5 0.19 10.8 0.0 3.8 3 1 1 4 4 4 1 Dopey, N-terminal Arm PF00514.23 ORX75453.1 - 0.0073 16.3 0.4 31 4.8 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 ORX75453.1 - 0.028 14.4 0.2 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Tti2 PF10521.9 ORX75453.1 - 0.087 12.4 0.8 4.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Tti2 family MMS19_C PF12460.8 ORX75453.1 - 0.094 11.8 0.0 9.3 5.2 0.0 3.7 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal PAP2_3 PF14378.6 ORX75454.1 - 6e-22 78.3 8.9 1.1e-21 77.4 8.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 ORX75454.1 - 2.8e-09 36.8 4.3 2.8e-09 36.8 4.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_M48_N PF16491.5 ORX75455.1 - 1.1e-67 227.4 4.7 1.1e-67 227.4 4.7 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORX75455.1 - 7.2e-30 104.2 0.0 1.1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ORX75455.1 - 0.016 14.4 3.4 1.2 8.3 0.1 3.0 3 0 0 3 3 3 0 BlaR1 peptidase M56 Peptidase_M43 PF05572.13 ORX75455.1 - 0.081 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A SDF PF00375.18 ORX75466.1 - 5.1e-101 338.5 38.7 5.8e-101 338.3 38.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LapA_dom PF06305.11 ORX75466.1 - 0.0011 18.7 0.7 0.0011 18.7 0.7 3.3 4 0 0 4 4 4 1 Lipopolysaccharide assembly protein A domain AIP3 PF03915.13 ORX75467.1 - 4.3e-86 289.6 11.5 5.4e-86 289.2 11.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 MREG PF15812.5 ORX75467.1 - 0.27 11.5 2.2 0.29 11.4 0.4 1.9 2 0 0 2 2 2 0 Melanoregulin Fib_alpha PF08702.10 ORX75467.1 - 0.68 10.1 12.7 0.061 13.5 4.5 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORX75467.1 - 8.9 6.9 12.0 45 4.6 0.0 5.0 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.13 ORX75468.1 - 0.0013 19.3 1.4 0.0013 19.3 1.4 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Histidinol_dh PF00815.20 ORX75468.1 - 0.0051 15.9 1.8 0.0057 15.7 1.8 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PLC-beta_C PF08703.10 ORX75468.1 - 0.018 15.1 3.8 0.043 13.8 3.8 1.6 1 1 0 1 1 1 0 PLC-beta C terminal FIVAR PF07554.13 ORX75468.1 - 0.025 15.3 3.8 0.03 15.1 3.8 1.2 1 0 0 1 1 1 0 FIVAR domain ASPRs PF17641.2 ORX75468.1 - 0.029 14.7 0.4 0.033 14.5 0.4 1.0 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related DUF5486 PF17588.2 ORX75468.1 - 0.046 13.6 1.4 0.075 12.9 0.7 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5486) Thymidylate_kin PF02223.17 ORX75468.1 - 0.049 13.3 0.2 0.057 13.1 0.2 1.0 1 0 0 1 1 1 0 Thymidylate kinase YtxH PF12732.7 ORX75468.1 - 0.051 14.1 4.6 0.1 13.1 4.6 1.7 1 1 0 1 1 1 0 YtxH-like protein GrpE PF01025.19 ORX75468.1 - 0.27 10.9 5.9 0.35 10.5 5.9 1.1 1 0 0 1 1 1 0 GrpE Glyco_transf_20 PF00982.21 ORX75469.1 - 3.2e-54 184.4 1.9 1.1e-46 159.5 0.1 3.1 3 0 0 3 3 3 3 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORX75469.1 - 4.7e-44 150.3 0.2 1.5e-33 115.9 0.0 2.6 1 1 1 2 2 2 2 Trehalose-phosphatase AOX PF01786.17 ORX75482.1 - 4.3e-85 284.7 0.6 5.6e-85 284.3 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase Glyco_hydro_32N PF00251.20 ORX75483.1 - 4.4e-55 187.4 3.4 8.6e-55 186.4 3.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORX75483.1 - 4e-33 114.7 0.2 6.1e-33 114.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 ORX75483.1 - 0.0056 16.8 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 ORX75483.1 - 0.069 13.2 0.9 1 9.6 0.2 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Phosphorylase PF00343.20 ORX75484.1 - 0 1073.3 0.0 0 1073.0 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase HA70_C PF17993.1 ORX75484.1 - 0.0028 17.7 0.2 0.047 13.7 0.1 2.5 2 0 0 2 2 2 1 Haemagglutinin 70 C-terminal domain Zip PF02535.22 ORX75485.1 - 1.7e-51 175.4 11.8 3.8e-51 174.3 11.8 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter COX6B PF02297.17 ORX75486.1 - 1.2e-13 51.1 0.1 1.5e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sugar_tr PF00083.24 ORX75487.1 - 4.4e-53 180.7 17.0 5.7e-53 180.4 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX75487.1 - 4.7e-26 91.5 27.9 2.7e-25 89.1 27.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX75487.1 - 0.00017 21.0 3.3 0.00017 21.0 3.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ORX75487.1 - 0.014 13.8 1.2 0.026 12.9 1.2 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector SUR7 PF06687.12 ORX75515.1 - 3.3 7.3 18.3 4.3 6.9 18.3 1.3 1 0 0 1 1 1 0 SUR7/PalI family Sh_2 PF17512.2 ORX75515.1 - 5.2 6.8 9.9 7.7 6.3 9.9 1.4 1 1 0 1 1 1 0 Metapneumovirus Small hydrophobic protein DUF3674 PF12426.8 ORX75519.1 - 0.04 13.9 0.8 5.1 7.2 0.3 2.5 2 0 0 2 2 2 0 RNA dependent RNA polymerase Pyr_redox_2 PF07992.14 ORX75525.1 - 1.1e-59 202.1 0.1 1.8e-59 201.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TusA PF01206.17 ORX75525.1 - 4.1e-16 58.6 0.0 7.9e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA Pyr_redox PF00070.27 ORX75525.1 - 1.8e-14 54.1 3.2 1.9e-14 54.0 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX75525.1 - 7.6e-14 51.9 3.4 1.6e-12 47.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 ORX75525.1 - 6.7e-13 49.1 0.0 2.1e-12 47.5 0.0 1.8 2 0 0 2 2 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 ORX75525.1 - 1.3e-10 41.0 1.4 2.1e-09 37.1 0.1 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX75525.1 - 7.6e-07 29.3 2.7 0.038 14.2 0.2 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX75525.1 - 0.00048 20.1 2.3 1.2 9.1 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX75525.1 - 0.0012 18.0 3.0 0.087 11.9 0.4 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 ORX75525.1 - 0.0059 15.9 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 ORX75525.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 ORX75525.1 - 0.028 14.0 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_binding_2 PF00890.24 ORX75525.1 - 0.029 13.4 5.7 1.2 8.2 0.3 3.2 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 ORX75525.1 - 0.04 13.8 0.9 0.07 13.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RELT PF12606.8 ORX75525.1 - 0.044 12.8 0.1 0.077 12.0 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 HI0933_like PF03486.14 ORX75525.1 - 0.06 12.0 6.1 1.8 7.2 1.0 3.1 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 ORX75525.1 - 0.098 11.9 0.8 0.25 10.5 0.6 1.7 1 1 0 1 1 1 0 FAD binding domain DAO PF01266.24 ORX75525.1 - 0.12 11.9 6.6 0.81 9.2 0.2 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase ADH_N PF08240.12 ORX75547.1 - 2.9e-23 81.8 0.7 2.9e-23 81.8 0.7 1.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX75547.1 - 3.7e-15 56.1 0.0 7.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX75547.1 - 9.1e-06 25.1 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX75547.1 - 3e-05 23.5 0.0 5.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ORX75547.1 - 0.00046 21.3 0.0 0.00086 20.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 ORX75547.1 - 0.055 13.2 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase EIF_2_alpha PF07541.12 ORX75547.1 - 0.082 13.0 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit 3HCDH_N PF02737.18 ORX75547.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kazal_1 PF00050.21 ORX75547.1 - 0.19 11.8 1.7 2.3 8.3 0.7 2.4 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DUF1325 PF07039.11 ORX75548.1 - 6.6e-35 120.1 0.6 1.2e-34 119.2 0.6 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 ORX75548.1 - 0.0096 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 ORX75548.1 - 0.028 14.9 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 Agenet domain HLH PF00010.26 ORX75565.1 - 5.5e-15 55.1 1.8 5.5e-15 55.1 1.8 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Fib_alpha PF08702.10 ORX75565.1 - 0.0057 16.9 2.2 0.0091 16.2 2.2 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family FapA PF03961.13 ORX75565.1 - 0.35 9.4 2.5 0.49 8.9 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 ORX75565.1 - 0.57 10.0 5.2 0.12 12.1 1.4 1.7 2 0 0 2 2 2 0 Septum formation initiator LINES_N PF14694.6 ORX75566.1 - 4.9e-09 36.1 1.1 6.9e-09 35.6 1.1 1.3 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 ORX75566.1 - 1.6e-05 24.2 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Lines C-terminus UQ_con PF00179.26 ORX75567.1 - 8e-48 161.7 0.0 9e-48 161.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORX75567.1 - 0.00071 19.3 0.0 0.00094 18.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORX75567.1 - 0.0095 15.8 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 ORX75567.1 - 0.053 13.8 0.1 0.059 13.7 0.1 1.3 1 1 0 1 1 1 0 RWD domain Peptidase_M64 PF09471.10 ORX75568.1 - 3.7e-29 102.1 0.0 3e-28 99.1 0.0 2.1 1 1 0 1 1 1 1 IgA Peptidase M64 Hemerythrin PF01814.23 ORX75582.1 - 1.1e-14 55.1 4.6 3.6e-14 53.5 3.2 2.0 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain PP2C_C PF07830.13 ORX75582.1 - 0.21 12.0 3.1 0.22 12.0 0.8 2.1 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Transket_pyr PF02779.24 ORX75583.1 - 2.7e-42 144.4 0.0 3.8e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORX75583.1 - 8e-33 113.0 0.0 1.4e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Flavoprotein PF02441.19 ORX75584.1 - 2e-54 183.6 0.2 2.3e-54 183.4 0.2 1.0 1 0 0 1 1 1 1 Flavoprotein Arrestin_C PF02752.22 ORX75585.1 - 3.4e-13 50.2 0.1 8.2e-12 45.7 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX75585.1 - 2.1e-10 40.8 0.0 5.6e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX75585.1 - 0.056 13.2 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like MLANA PF14991.6 ORX75585.1 - 0.17 12.1 2.1 0.28 11.4 2.1 1.3 1 0 0 1 1 1 0 Protein melan-A GatB_N PF02934.15 ORX75585.1 - 0.19 11.1 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 GatB/GatE catalytic domain Pkinase PF00069.25 ORX75587.1 - 1.1e-66 224.9 0.0 1.7e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX75587.1 - 1.5e-31 109.7 0.0 3.2e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX75587.1 - 0.0001 21.7 0.0 0.0008 18.8 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX75587.1 - 0.00014 20.9 1.1 0.00018 20.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 ORX75587.1 - 0.00046 19.6 0.2 0.0008 18.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX75587.1 - 0.0038 16.0 0.1 0.0078 15.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX75587.1 - 0.0054 16.7 0.1 0.055 13.4 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family HLH PF00010.26 ORX75588.1 - 1.9e-13 50.1 0.9 1.9e-13 50.1 0.9 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 ORX75588.1 - 0.0005 20.1 0.8 0.0005 20.1 0.8 2.7 2 0 0 2 2 2 1 TolA binding protein trimerisation HALZ PF02183.18 ORX75588.1 - 0.0038 17.4 1.1 0.0038 17.4 1.1 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF3450 PF11932.8 ORX75588.1 - 0.0053 16.1 2.8 0.0053 16.1 2.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Phage_CP76 PF06892.11 ORX75588.1 - 0.0082 15.7 0.6 0.019 14.5 0.6 1.6 1 0 0 1 1 1 1 Phage regulatory protein CII (CP76) bZIP_1 PF00170.21 ORX75588.1 - 0.014 15.5 2.1 0.014 15.5 2.1 2.8 2 1 0 2 2 2 0 bZIP transcription factor APC_N_CC PF16689.5 ORX75588.1 - 0.024 14.7 6.2 0.04 14.0 1.4 3.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_2 PF07716.15 ORX75588.1 - 0.027 14.5 1.3 0.027 14.5 1.3 2.8 4 0 0 4 4 2 0 Basic region leucine zipper FlaC_arch PF05377.11 ORX75588.1 - 0.049 14.0 0.5 0.049 14.0 0.5 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pox_A30L_A26L PF06086.12 ORX75588.1 - 0.096 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein LPP PF04728.13 ORX75588.1 - 0.12 12.8 0.7 0.12 12.8 0.7 2.6 3 1 0 3 3 2 0 Lipoprotein leucine-zipper TSC22 PF01166.18 ORX75588.1 - 0.16 12.3 0.6 0.16 12.3 0.6 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family SlyX PF04102.12 ORX75588.1 - 0.75 10.5 10.5 1.2 9.8 1.9 2.9 2 1 0 2 2 2 0 SlyX MctB PF11382.8 ORX75588.1 - 4.3 6.9 9.4 0.3 10.8 1.3 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB Methyltransf_23 PF13489.6 ORX75602.1 - 2.9e-15 56.5 0.0 4.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX75602.1 - 1.4e-10 41.7 0.0 4e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX75602.1 - 5.8e-09 36.5 0.1 5.3e-08 33.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX75602.1 - 1.6e-08 35.2 0.0 6.1e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX75602.1 - 5.4e-08 32.8 0.0 2.6e-07 30.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain CheR PF01739.18 ORX75602.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 ORX75602.1 - 0.026 13.9 0.2 0.26 10.7 0.0 2.4 1 1 1 3 3 3 0 Tellurite resistance protein TehB Methyltransf_28 PF02636.17 ORX75602.1 - 0.033 13.8 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_20 PF12147.8 ORX75602.1 - 0.042 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 ORX75602.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Band_7 PF01145.25 ORX75603.1 - 6.2e-27 94.7 0.6 8.8e-27 94.2 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX75603.1 - 0.046 13.4 0.1 0.093 12.4 0.1 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORX75603.1 - 0.058 13.0 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Thaumatin PF00314.17 ORX75604.1 - 3.2e-68 229.5 12.9 3.7e-68 229.4 12.9 1.0 1 0 0 1 1 1 1 Thaumatin family Mito_carr PF00153.27 ORX75662.1 - 2.6e-28 97.8 0.1 2.7e-18 65.7 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Arrestin_C PF02752.22 ORX75683.1 - 2.5e-13 50.7 0.1 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX75683.1 - 1.1e-09 38.5 0.1 4.1e-09 36.6 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX75683.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like COX16 PF14138.6 ORX75684.1 - 3.9e-29 101.0 0.1 4.7e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Polysacc_deac_1 PF01522.21 ORX75685.1 - 2.7e-29 101.6 0.0 3.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase PNP_UDP_1 PF01048.20 ORX75698.1 - 1.9e-35 122.2 0.0 2.6e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PH PF00169.29 ORX75700.1 - 5.4e-15 55.8 1.5 6.4e-15 55.6 1.5 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORX75700.1 - 2.4e-07 31.1 1.6 3.5e-07 30.6 1.5 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 ORX75700.1 - 1.2e-05 25.4 0.3 1.5e-05 25.0 0.3 1.1 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 ORX75700.1 - 0.00031 20.9 0.3 0.00046 20.4 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 ORX75700.1 - 0.0015 18.9 1.5 0.015 15.7 1.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_15 PF17339.2 ORX75700.1 - 0.037 13.9 2.1 0.046 13.6 2.1 1.3 1 1 0 1 1 1 0 PH domain bZIP_1 PF00170.21 ORX75714.1 - 0.055 13.6 4.5 0.86 9.7 0.2 2.8 2 0 0 2 2 2 0 bZIP transcription factor EFG_C PF00679.24 ORX75714.1 - 0.061 13.4 0.9 0.15 12.1 0.3 2.0 2 0 0 2 2 2 0 Elongation factor G C-terminus FlxA PF14282.6 ORX75714.1 - 0.11 12.5 5.6 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 FlxA-like protein Leu_zip PF15294.6 ORX75714.1 - 0.14 11.7 9.1 0.2 11.1 9.1 1.3 1 0 0 1 1 1 0 Leucine zipper DMPK_coil PF08826.10 ORX75714.1 - 1.5 9.0 6.8 9.2 6.5 1.3 2.7 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF4267 PF14087.6 ORX75751.1 - 0.0072 16.4 0.3 4 7.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4267) VP4_helical PF17478.2 ORX75751.1 - 0.017 14.6 2.9 0.72 9.2 0.7 2.0 1 1 1 2 2 2 0 Rotavirus VP4 helical domain DUF4148 PF13663.6 ORX75751.1 - 0.18 12.0 1.1 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Hep_core_N PF08290.11 ORX75751.1 - 0.62 10.1 6.2 7.5 6.7 0.6 3.1 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger YbgS PF13985.6 ORX75751.1 - 2.5 8.4 4.8 24 5.2 0.1 2.9 2 2 1 3 3 3 0 YbgS-like protein Defensin_int PF17858.1 ORX75751.1 - 5.2 7.1 16.9 3.2 7.8 0.3 3.2 2 1 1 3 3 3 0 Platypus intermediate defensin-like peptide DIM PF08194.12 ORX75751.1 - 6.9 7.0 7.9 25 5.2 0.1 3.2 3 0 0 3 3 3 0 DIM protein Pyr_redox_2 PF07992.14 ORX75753.1 - 5.5e-60 203.1 0.0 8.8e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TusA PF01206.17 ORX75753.1 - 8.5e-17 60.8 0.1 1.6e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA Pyr_redox PF00070.27 ORX75753.1 - 5.3e-15 55.7 2.3 1.3e-14 54.5 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX75753.1 - 9e-14 51.7 0.9 9e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 ORX75753.1 - 1.3e-10 41.1 1.0 3.5e-09 36.4 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 ORX75753.1 - 1.7e-10 41.3 0.0 6.3e-10 39.5 0.0 2.0 2 0 0 2 2 1 1 Rhodanese-like domain NAD_binding_8 PF13450.6 ORX75753.1 - 5.8e-08 32.8 3.1 0.0053 17.0 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX75753.1 - 0.00068 18.8 3.9 0.14 11.2 0.4 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORX75753.1 - 0.00076 19.5 3.2 4.6 7.2 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORX75753.1 - 0.006 15.7 5.2 4.6 6.2 0.7 3.3 3 0 0 3 3 3 2 FAD binding domain DUF1188 PF06690.11 ORX75753.1 - 0.012 15.1 0.1 0.051 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) DAO PF01266.24 ORX75753.1 - 0.012 15.2 7.7 0.75 9.3 0.7 3.8 2 2 1 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORX75753.1 - 0.014 14.5 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ORX75753.1 - 0.015 14.0 6.3 3 6.5 0.0 3.4 3 1 1 4 4 4 0 HI0933-like protein 3HCDH_N PF02737.18 ORX75753.1 - 0.094 12.6 1.2 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORX75753.1 - 0.11 11.7 0.1 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 ORX75753.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family GST_N_3 PF13417.6 ORX75754.1 - 2.2e-13 50.4 0.0 3.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX75754.1 - 2.8e-11 43.5 0.3 7.5e-11 42.2 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX75754.1 - 3.7e-09 36.7 0.0 7.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX75754.1 - 1.3e-08 35.0 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX75754.1 - 1.7e-07 31.1 0.1 4.7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX75754.1 - 1.5e-06 28.3 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX75754.1 - 0.00011 22.7 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORX75754.1 - 0.0045 16.8 0.1 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin 2, C terminal domain Myb_DNA-bind_4 PF13837.6 ORX75784.1 - 1.9e-19 69.8 4.7 1.9e-19 69.8 4.7 2.6 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain SUIM_assoc PF16619.5 ORX75784.1 - 1.8e-05 24.7 15.1 0.0018 18.3 4.6 4.7 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 MADF_DNA_bdg PF10545.9 ORX75784.1 - 6.1e-05 23.3 3.3 6.1e-05 23.3 3.3 3.0 3 1 1 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 ORX75784.1 - 0.00094 19.4 2.9 0.00094 19.4 2.9 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX75784.1 - 0.0026 17.9 2.5 0.0059 16.8 2.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORX75784.1 - 0.0049 17.8 2.2 0.0049 17.8 2.2 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain RR_TM4-6 PF06459.12 ORX75784.1 - 0.32 10.8 12.7 0.35 10.7 4.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PepSY_TM PF03929.16 ORX75784.1 - 9.1 5.9 6.9 6.2 6.4 4.7 1.9 2 0 0 2 2 2 0 PepSY-associated TM region CoA_binding PF02629.19 ORX75786.1 - 5.8e-30 103.8 0.3 5.8e-30 103.8 0.3 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ORX75786.1 - 6.5e-24 84.5 0.2 1.4e-23 83.5 0.0 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 ORX75786.1 - 9e-07 28.8 0.0 2.7e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ORX75786.1 - 2.9e-06 27.8 0.1 9e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 ORX75786.1 - 0.12 13.2 0.0 0.38 11.6 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold FAM53 PF15242.6 ORX75787.1 - 0.025 14.4 0.8 0.028 14.3 0.8 1.2 1 0 0 1 1 1 0 Family of FAM53 DUF4200 PF13863.6 ORX75787.1 - 0.026 14.9 7.7 0.045 14.1 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Hormone_3 PF00159.18 ORX75787.1 - 0.89 9.7 3.2 10 6.3 0.0 3.1 4 0 0 4 4 4 0 Pancreatic hormone peptide CENP-H PF05837.12 ORX75787.1 - 6.2 7.3 8.7 7.9 6.9 6.9 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Amidase PF01425.21 ORX75788.1 - 8.4e-86 288.7 0.1 8.7e-84 282.1 0.1 2.0 1 1 0 1 1 1 1 Amidase RDM PF11002.8 ORX75788.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 RFPL defining motif (RDM) Spc7 PF08317.11 ORX75790.1 - 0.0019 17.1 4.3 0.0025 16.8 4.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tho2 PF11262.8 ORX75790.1 - 0.021 14.0 0.5 0.027 13.7 0.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GRA6 PF05084.13 ORX75790.1 - 0.12 12.4 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) CENP-H PF05837.12 ORX75790.1 - 2.5 8.6 11.1 2.3 8.7 8.4 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Pkinase PF00069.25 ORX75791.1 - 1.2e-71 241.2 0.0 1.4e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX75791.1 - 2e-32 112.5 0.0 2.6e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX75791.1 - 0.0055 15.7 0.0 0.063 12.2 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX75791.1 - 0.097 12.0 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 ORX75791.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_31 PF13847.6 ORX75804.1 - 1e-19 70.9 0.0 1.5e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX75804.1 - 7.2e-19 68.2 0.0 2.6e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX75804.1 - 2.4e-18 66.6 0.0 1.3e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX75804.1 - 3.1e-15 56.4 0.0 4.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX75804.1 - 2.1e-13 50.8 0.0 4.6e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX75804.1 - 1.5e-08 34.3 0.0 7.1e-08 32.1 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORX75804.1 - 3.9e-07 30.0 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 ORX75804.1 - 4.3e-06 26.2 0.0 7.9e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORX75804.1 - 9.3e-06 24.8 0.0 1.4e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 ORX75804.1 - 7.2e-05 22.8 0.0 9.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 ORX75804.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 ORX75804.1 - 0.00034 20.8 0.0 0.013 15.6 0.0 2.6 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 ORX75804.1 - 0.00084 18.7 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 ORX75804.1 - 0.0013 19.7 0.1 0.03 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORX75804.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 ORX75804.1 - 0.0073 15.8 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 CheR PF01739.18 ORX75804.1 - 0.012 15.1 0.0 0.14 11.6 0.0 2.2 2 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.26 ORX75804.1 - 0.017 15.1 0.1 0.043 13.8 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PALP PF00291.25 ORX75804.1 - 0.051 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_4 PF02390.17 ORX75804.1 - 0.11 12.0 0.0 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Abhydrolase_1 PF00561.20 ORX75805.1 - 2.7e-23 83.0 0.2 1.4e-21 77.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX75805.1 - 1.4e-18 68.3 0.1 1.8e-18 68.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX75805.1 - 6.5e-18 64.9 0.2 1.3e-17 63.9 0.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORX75805.1 - 2.5e-12 46.1 0.0 3.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 ORX75805.1 - 2.3e-05 24.4 0.1 6.7e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 ORX75805.1 - 0.0001 22.2 1.0 0.014 15.2 0.2 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 ORX75805.1 - 0.00011 22.3 0.0 0.00053 20.1 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Esterase PF00756.20 ORX75805.1 - 0.00089 19.0 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORX75805.1 - 0.0052 16.3 0.2 0.059 12.8 0.2 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.12 ORX75805.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.18 ORX75805.1 - 0.018 14.6 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORX75805.1 - 0.047 13.5 0.3 0.13 12.1 0.3 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 ORX75805.1 - 0.07 12.8 0.1 1.1 8.8 0.2 2.4 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Epimerase PF01370.21 ORX75806.1 - 0.00054 19.5 1.1 0.0042 16.6 0.2 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORX75806.1 - 0.003 17.1 0.3 0.026 14.1 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORX75806.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SIS PF01380.22 ORX75806.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 SIS domain KR PF08659.10 ORX75806.1 - 0.15 12.0 0.1 12 5.7 0.0 2.4 1 1 1 2 2 2 0 KR domain HSP70 PF00012.20 ORX75852.1 - 2e-262 871.7 6.4 2.3e-262 871.6 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX75852.1 - 3e-16 59.1 0.1 5.4e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX75852.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX75852.1 - 0.0094 15.2 0.1 0.023 14.0 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX75852.1 - 0.016 14.7 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX75852.1 - 0.059 13.6 4.7 0.85 9.8 1.0 2.4 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX75852.1 - 0.094 12.7 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DDR PF08841.10 ORX75852.1 - 0.094 11.7 0.3 0.82 8.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Golgin_A5 PF09787.9 ORX75852.1 - 7.3 6.0 8.9 3 7.2 5.2 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Inhibitor_Mig-6 PF11555.8 ORX75859.1 - 0.25 11.5 4.5 0.47 10.6 4.5 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 PRIMA1 PF16101.5 ORX75860.1 - 0.0073 16.3 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Proline-rich membrane anchor 1 PhoR PF11808.8 ORX75860.1 - 0.023 15.1 0.0 0.087 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR SKG6 PF08693.10 ORX75860.1 - 0.039 13.4 2.5 0.039 13.4 2.5 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 ORX75860.1 - 0.064 13.0 1.7 0.069 12.9 0.1 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 VSP PF03302.13 ORX75860.1 - 0.13 11.1 2.9 0.17 10.7 2.9 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein ThiF PF00899.21 ORX75861.1 - 7.1e-34 117.2 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORX75861.1 - 1.2e-05 25.6 0.5 7.4e-05 23.0 0.5 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ORX75861.1 - 0.00057 19.6 0.0 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ORX75861.1 - 0.0013 19.3 1.8 0.32 11.6 0.6 3.9 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX75861.1 - 0.0029 17.2 0.4 0.0054 16.4 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORX75861.1 - 0.0065 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORX75861.1 - 0.014 15.9 0.9 0.67 10.4 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ORX75861.1 - 0.017 14.3 0.4 0.1 11.8 0.2 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORX75861.1 - 0.03 14.4 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 ORX75861.1 - 0.031 13.4 0.1 0.054 12.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 ORX75861.1 - 0.032 13.6 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Stealth_CR3 PF17102.5 ORX75861.1 - 0.034 14.1 0.0 8.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 TrkA_N PF02254.18 ORX75861.1 - 0.036 14.3 0.2 0.1 12.9 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 ORX75861.1 - 0.11 12.4 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX75861.1 - 0.13 12.3 0.7 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Chromo PF00385.24 ORX75862.1 - 3.1e-09 36.6 3.4 3.1e-09 36.6 3.4 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1157 PF06636.11 ORX75862.1 - 0.22 10.3 0.1 0.35 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) FAM176 PF14851.6 ORX75862.1 - 9.3 5.9 9.6 11 5.6 4.8 2.4 2 0 0 2 2 2 0 FAM176 family Ribosomal_L22 PF00237.19 ORX75863.1 - 4.7e-25 87.8 0.1 6e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PAN_4 PF14295.6 ORX75883.1 - 1.7e-07 31.0 0.9 1.7e-07 31.0 0.9 1.9 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 ORX75883.1 - 0.00017 21.5 3.1 0.00036 20.4 3.1 1.5 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.12 ORX75883.1 - 0.00028 20.4 0.2 0.00064 19.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF604 UL2 PF08196.11 ORX75883.1 - 0.11 12.5 0.5 0.27 11.2 0.5 1.6 1 0 0 1 1 1 0 UL2 protein zf-RING_2 PF13639.6 ORX75884.1 - 2e-14 53.6 6.9 4e-14 52.7 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORX75884.1 - 5.5e-11 42.0 5.3 5.5e-11 42.0 5.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORX75884.1 - 3.1e-09 36.6 5.7 6.7e-09 35.5 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 ORX75884.1 - 7.1e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 ORX75884.1 - 1.3e-08 34.5 5.8 1.3e-08 34.5 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX75884.1 - 1.7e-07 31.0 3.9 1.7e-07 31.0 3.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORX75884.1 - 3.3e-07 30.5 8.7 2e-06 28.0 8.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX75884.1 - 5.3e-05 23.2 1.9 0.00011 22.2 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORX75884.1 - 0.00017 21.6 1.2 0.00017 21.6 1.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORX75884.1 - 0.00028 20.7 6.6 0.0005 19.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX75884.1 - 0.001 18.9 7.0 0.0023 17.8 7.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORX75884.1 - 0.0065 16.2 6.8 0.012 15.4 6.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORX75884.1 - 0.012 15.8 2.7 0.031 14.4 2.7 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 ORX75884.1 - 0.042 13.7 4.9 0.084 12.8 4.9 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ORX75884.1 - 0.22 11.7 6.5 1.1 9.5 6.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORX75884.1 - 0.57 9.8 4.0 1.2 8.8 4.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 ORX75884.1 - 1 9.7 4.6 0.52 10.7 1.8 1.9 2 0 0 2 2 2 0 RING-like domain 3HCDH_N PF02737.18 ORX75885.1 - 3.2e-56 190.1 1.1 4.2e-56 189.7 1.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORX75885.1 - 1.6e-34 118.4 0.0 3.2e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX75885.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EB PF01683.18 ORX75886.1 - 4.2e-05 23.7 34.1 0.2 12.0 3.6 4.4 2 1 2 4 4 4 4 EB module LapA_dom PF06305.11 ORX75886.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 ORX75886.1 - 0.19 12.6 0.4 1.1 10.2 0.1 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 ORX75886.1 - 0.27 11.5 0.0 0.27 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PDZ_1 PF12812.7 ORX75887.1 - 8.8e-38 128.2 0.0 1.4e-22 79.5 0.0 3.1 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 ORX75887.1 - 8.5e-23 81.9 0.2 3.4e-19 70.2 0.0 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 ORX75887.1 - 9.5e-21 73.9 0.0 9.6e-09 35.4 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 ORX75887.1 - 3.4e-19 68.4 0.0 4.4e-08 32.9 0.0 4.7 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORX75887.1 - 2.2e-12 47.1 0.0 2.6e-05 24.5 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 ORX75887.1 - 0.00061 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 ORX75887.1 - 0.00095 19.1 0.2 1.6 8.7 0.0 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain PDZ_3 PF17815.1 ORX75887.1 - 0.0091 15.9 0.1 17 5.3 0.0 3.9 4 1 1 5 5 5 1 PDZ domain DUF31 PF01732.16 ORX75887.1 - 0.18 11.3 0.4 0.27 10.7 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 ORX75887.1 - 0.29 9.7 0.0 2.2 6.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase S46 SNARE_assoc PF09335.11 ORX75888.1 - 6.2e-18 65.4 7.2 6.2e-18 65.4 7.2 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF202 PF02656.15 ORX75888.1 - 1 9.8 4.3 1.7 9.1 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) AMP-binding PF00501.28 ORX75915.1 - 1.5e-92 310.4 0.0 2e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ORX75915.1 - 3.2e-62 210.7 3.3 2.7e-51 174.7 0.8 3.2 3 0 0 3 3 3 3 Condensation domain Methyltransf_25 PF13649.6 ORX75915.1 - 1.5e-16 60.8 0.0 4.1e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX75915.1 - 1.1e-15 58.0 0.0 5.9e-15 55.7 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX75915.1 - 2.7e-15 56.9 0.0 6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX75915.1 - 7.4e-15 55.0 0.0 1.8e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX75915.1 - 1.3e-13 51.1 0.0 3.7e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 ORX75915.1 - 4.2e-12 46.9 0.5 3.2e-05 24.8 0.2 3.2 3 0 0 3 3 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX75915.1 - 1e-09 38.6 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site CMAS PF02353.20 ORX75915.1 - 4.1e-07 29.6 0.0 7.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORX75915.1 - 1.1e-06 28.2 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ORX75915.1 - 3.4e-05 23.6 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 ORX75915.1 - 7.9e-05 22.3 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ORX75915.1 - 0.0027 17.1 0.0 0.0098 15.3 0.0 1.8 2 0 0 2 2 2 1 Tellurite resistance protein TehB MetW PF07021.12 ORX75915.1 - 0.0038 16.9 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 ORX75915.1 - 0.053 13.0 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.11 ORX75915.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 ORX75915.1 - 0.066 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 ORX75915.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 ORX75915.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 ORX75916.1 - 3.2e-59 200.9 0.0 3.5e-58 197.5 0.0 1.8 1 1 1 2 2 2 2 Cytochrome P450 Ank PF00023.30 ORX75931.1 - 7.9e-24 83.0 0.2 2.1e-05 24.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 ORX75931.1 - 2.1e-23 82.7 0.0 1.4e-10 41.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX75931.1 - 9.4e-21 73.6 0.4 3.4e-07 30.4 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX75931.1 - 3.2e-18 63.9 0.2 0.0011 19.2 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORX75931.1 - 5.9e-14 52.2 0.0 0.00015 22.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Mic1 PF07035.12 ORX75931.1 - 0.16 11.7 0.1 5 6.8 0.1 2.5 2 1 1 3 3 3 0 Colon cancer-associated protein Mic1-like Cullin PF00888.22 ORX75932.1 - 0.036 12.7 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Cullin family DUF4449 PF14613.6 ORX75933.1 - 0.00037 20.6 3.9 0.00037 20.6 3.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 ORX75933.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Myticin-prepro PF10690.9 ORX75961.1 - 0.0042 17.3 0.4 0.0077 16.5 0.4 1.4 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel DUF562 PF04763.12 ORX76027.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF562) GRP PF07172.11 ORX76028.1 - 0.022 15.5 16.6 0.039 14.6 16.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family Sod_Ni PF09055.11 ORX76028.1 - 0.19 12.3 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase DUF4179 PF13786.6 ORX76031.1 - 0.11 12.9 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Mito_carr PF00153.27 ORX76069.1 - 4.7e-61 202.7 0.6 2.2e-22 78.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Csm1_N PF18504.1 ORX76070.1 - 0.0064 16.8 5.3 0.0064 16.8 5.3 4.8 3 2 2 5 5 5 1 Csm1 N-terminal domain Shugoshin_N PF07558.11 ORX76070.1 - 0.02 14.8 12.3 0.12 12.3 0.5 3.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 ORX76070.1 - 0.052 12.4 22.7 0.14 11.0 5.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 ORX76070.1 - 0.21 11.1 29.1 0.38 10.3 11.8 2.6 3 0 0 3 3 3 0 Intermediate filament protein FPP PF05911.11 ORX76070.1 - 0.23 9.6 24.6 0.022 13.0 3.9 2.3 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2205 PF10224.9 ORX76070.1 - 0.42 10.6 0.1 0.42 10.6 0.1 4.2 4 0 0 4 4 4 0 Short coiled-coil protein RBD-FIP PF09457.10 ORX76070.1 - 0.54 10.2 5.6 0.95 9.4 0.6 3.1 3 0 0 3 3 3 0 FIP domain GAS PF13851.6 ORX76070.1 - 1 8.7 29.4 0.65 9.3 8.2 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Herpes_UL6 PF01763.16 ORX76070.1 - 1.8 7.0 13.4 0.32 9.4 2.7 2.2 2 0 0 2 2 2 0 Herpesvirus UL6 like CCDC144C PF14915.6 ORX76070.1 - 1.8 7.6 31.8 1.1 8.3 29.3 1.9 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region DUF4407 PF14362.6 ORX76070.1 - 2.6 7.3 10.8 7.1 5.9 10.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 ORX76070.1 - 3.1 7.0 21.8 0.95 8.6 5.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein TFR_dimer PF04253.15 ORX76070.1 - 4.3 7.5 6.8 6.7 6.8 0.1 2.8 3 1 0 3 3 2 0 Transferrin receptor-like dimerisation domain bZIP_1 PF00170.21 ORX76070.1 - 5.8 7.1 33.0 12 6.0 0.0 6.1 5 1 1 6 6 6 0 bZIP transcription factor Peptidase_M16 PF00675.20 ORX76070.1 - 6.1 6.8 9.9 0.69 9.9 2.9 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) ATG16 PF08614.11 ORX76070.1 - 6.6 6.9 39.7 1 9.5 9.5 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) NlpE PF04170.12 ORX76070.1 - 7.2 7.7 8.0 21 6.2 2.8 3.2 3 0 0 3 3 3 0 NlpE N-terminal domain APC_u15 PF16636.5 ORX76070.1 - 9.7 6.7 7.3 18 5.9 0.9 2.7 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Ank_2 PF12796.7 ORX76071.1 - 2.9e-06 27.8 0.1 5.4e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX76071.1 - 1.1e-05 25.7 1.0 2e-05 24.8 0.3 1.8 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORX76071.1 - 0.00023 21.7 0.0 0.08 13.5 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX76071.1 - 0.00045 20.5 0.1 0.018 15.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 ORX76071.1 - 0.00067 19.9 0.1 0.0015 18.8 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Polysacc_deac_1 PF01522.21 ORX76073.1 - 5.8e-27 94.0 0.0 3.6e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Fes1 PF08609.10 ORX76074.1 - 4.9e-24 85.0 2.4 4.9e-24 85.0 2.4 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 ORX76074.1 - 2.9e-06 27.6 0.1 0.008 16.5 0.0 2.3 1 1 2 3 3 3 2 HEAT repeats DUF3361 PF11841.8 ORX76074.1 - 4.3e-05 23.5 0.1 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) HEAT PF02985.22 ORX76074.1 - 0.00023 21.1 0.1 0.86 10.0 0.0 3.0 2 0 0 2 2 2 2 HEAT repeat Cnd1 PF12717.7 ORX76074.1 - 0.00074 19.6 0.0 0.0095 16.0 0.0 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 ORX76074.1 - 0.0036 17.3 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 ORX76074.1 - 0.0048 16.9 0.0 0.3 11.2 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 ORX76074.1 - 0.011 15.8 0.8 0.33 11.1 0.0 3.0 2 2 1 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 ORX76074.1 - 0.095 13.2 0.1 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat EF-hand_13 PF17958.1 ORX76074.1 - 0.13 12.0 0.1 5.4 6.9 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain PTR2 PF00854.21 ORX76092.1 - 1.3e-80 271.1 7.9 1.3e-80 271.1 7.9 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX76092.1 - 1.6e-14 53.6 28.1 3.5e-08 32.7 10.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Phage_holin_4_2 PF04020.13 ORX76092.1 - 2.2 9.0 11.6 2.2 9.0 0.6 3.5 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV Glyco_transf_34 PF05637.12 ORX76094.1 - 1.7e-24 86.9 4.2 1.2e-11 44.8 0.3 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORX76094.1 - 4.5e-05 23.1 0.3 0.00011 21.9 0.1 1.6 1 1 0 2 2 2 1 Protein of unknown function, DUF273 AA_permease PF00324.21 ORX76095.1 - 6.9e-126 420.6 47.9 8.3e-126 420.4 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX76095.1 - 3.4e-28 98.6 53.0 4.4e-28 98.3 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 ORX76095.1 - 0.025 14.3 0.7 0.057 13.1 0.7 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 Isochorismatase PF00857.20 ORX76096.1 - 2.9e-18 66.7 0.0 6e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family EBP PF05241.12 ORX76142.1 - 4.1e-47 159.9 2.4 4.9e-47 159.7 2.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein Peptidase_S8 PF00082.22 ORX76224.1 - 1.1e-32 113.5 14.6 2.3e-32 112.4 14.6 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX76224.1 - 3.3e-07 30.9 0.1 5.8e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 CAP PF00188.26 ORX76225.1 - 4.9e-14 53.2 0.1 6.3e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family tRNA-synt_1f PF01921.18 ORX76226.1 - 0.23 10.3 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Pyr_redox_2 PF07992.14 ORX76228.1 - 1.4e-19 70.4 0.0 3.9e-12 46.0 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX76228.1 - 0.00053 20.5 1.4 0.12 13.0 0.2 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX76228.1 - 0.0031 16.8 0.1 1.4 8.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX76228.1 - 0.0042 16.7 1.8 1.8 8.1 0.2 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORX76228.1 - 0.0049 16.9 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX76228.1 - 0.0081 15.2 0.1 0.24 10.4 0.1 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORX76228.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 ORX76228.1 - 0.03 13.6 0.7 0.072 12.3 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ORX76228.1 - 0.043 13.1 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ORX76228.1 - 0.079 11.8 0.1 0.44 9.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 ORX76228.1 - 0.081 13.2 0.2 0.25 11.6 0.1 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORX76228.1 - 0.11 11.2 0.8 2.7 6.6 0.2 2.5 2 1 0 2 2 2 0 HI0933-like protein Mob1_phocein PF03637.17 ORX76229.1 - 4.8e-68 228.5 0.4 5.6e-68 228.2 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_S27e PF01667.17 ORX76230.1 - 1.1e-26 92.3 5.3 1.2e-26 92.2 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORX76230.1 - 0.058 12.9 3.2 0.079 12.5 3.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Sel1 PF08238.12 ORX76231.1 - 2.9e-124 402.7 62.1 2.1e-10 40.9 0.0 14.7 14 0 0 14 14 14 14 Sel1 repeat Mito_carr PF00153.27 ORX76231.1 - 1.1e-62 207.9 0.7 1.9e-19 69.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_16 PF13432.6 ORX76231.1 - 0.089 13.5 14.6 0.23 12.1 0.1 6.1 5 2 1 7 7 7 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 ORX76232.1 - 1e-51 176.3 0.0 1.2e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX76232.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORX76232.1 - 0.018 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Bclx_interact PF08945.10 ORX76232.1 - 7.6 6.4 5.5 14 5.5 0.2 3.0 3 0 0 3 3 3 0 Bcl-x interacting, BH3 domain Peptidase_S9 PF00326.21 ORX76233.1 - 2.2e-43 148.2 0.0 3.3e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORX76233.1 - 6.7e-07 29.1 0.0 1.6e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORX76233.1 - 0.00029 20.5 0.0 0.0049 16.5 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORX76233.1 - 0.0041 15.8 0.3 0.073 11.7 0.3 2.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 ORX76233.1 - 0.0054 16.3 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase DUF829 PF05705.14 ORX76233.1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_4 PF08386.10 ORX76233.1 - 0.046 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 ORX76233.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2920 PF11144.8 ORX76233.1 - 0.091 11.9 0.1 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 ORX76233.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Acetyltransf_1 PF00583.25 ORX76234.1 - 1.4e-14 54.4 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX76234.1 - 1.9e-08 34.6 0.1 3.2e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX76234.1 - 6e-08 32.7 0.0 8.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 ORX76234.1 - 0.0026 16.4 0.0 0.0093 14.5 0.0 1.8 2 0 0 2 2 2 1 Arginine N-succinyltransferase beta subunit Glycogen_syn PF05693.13 ORX76255.1 - 1.4e-58 199.0 0.1 1.6e-58 198.8 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase HLH PF00010.26 ORX76256.1 - 5.3e-12 45.5 0.2 1e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 ORX76256.1 - 0.016 15.4 0.7 0.029 14.6 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2423 PF10338.9 ORX76256.1 - 0.016 15.4 2.1 0.03 14.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) bZIP_1 PF00170.21 ORX76256.1 - 0.017 15.2 2.2 0.021 14.9 0.5 1.9 2 0 0 2 2 2 0 bZIP transcription factor Fungal_TACC PF12709.7 ORX76256.1 - 0.043 14.3 0.1 0.087 13.3 0.1 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2381 PF09544.10 ORX76256.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) K-box PF01486.17 ORX76256.1 - 0.11 12.7 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 K-box region bZIP_2 PF07716.15 ORX76256.1 - 6 7.0 7.5 0.25 11.4 1.4 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 ORX76257.1 - 1.6e-44 152.3 0.0 3.4e-29 102.0 0.1 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX76257.1 - 1.1e-31 110.0 0.0 1.3e-18 67.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase DUF1241 PF06840.11 ORX76257.1 - 1.5e-05 24.7 0.1 2.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Csm1_N PF18504.1 ORX76257.1 - 0.071 13.5 0.4 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain PBD PF00786.28 ORX76258.1 - 0.00021 21.6 0.7 0.00032 21.0 0.5 1.6 1 1 0 1 1 1 1 P21-Rho-binding domain PITH PF06201.13 ORX76259.1 - 8.5e-40 136.4 5.7 8.5e-40 136.4 5.7 1.8 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 ORX76259.1 - 5.7e-25 87.3 0.3 1.5e-24 86.0 0.3 1.7 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORX76259.1 - 2e-07 30.7 0.2 3.6e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORX76259.1 - 2.7e-05 24.5 2.4 0.00023 21.6 0.8 2.7 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORX76259.1 - 0.00035 20.8 0.3 0.00095 19.5 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ORX76259.1 - 0.0026 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 ORX76259.1 - 0.0037 17.0 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 ORX76259.1 - 0.0049 16.8 0.2 0.012 15.6 0.2 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ORX76259.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like WES_acyltransf PF03007.16 ORX76259.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain WD40 PF00400.32 ORX76260.1 - 2.6e-23 81.9 9.2 0.00013 22.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX76260.1 - 1.2e-06 28.7 0.2 0.0025 18.1 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S5 PF00333.20 ORX76285.1 - 1.3e-29 102.0 0.4 1.3e-29 102.0 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX76285.1 - 3.2e-26 90.6 0.1 5.2e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORX76285.1 - 0.77 10.3 10.5 1.5 9.4 10.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MAAL_C PF07476.11 ORX76286.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus AA_permease_2 PF13520.6 ORX76301.1 - 6.2e-54 183.4 45.7 7.7e-54 183.1 45.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX76301.1 - 2e-41 142.1 42.1 2.5e-41 141.8 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX76301.1 - 1.4e-08 34.7 2.7 1.4e-08 34.7 2.7 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease NADHdh_A3 PF14987.6 ORX76301.1 - 1.8 8.9 4.6 0.99 9.8 1.0 2.6 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 AA_permease_2 PF13520.6 ORX76302.1 - 0.0017 17.3 19.6 0.0031 16.4 19.7 1.4 1 1 0 1 1 1 1 Amino acid permease Xan_ur_permease PF00860.20 ORX76302.1 - 0.0046 15.7 7.6 0.0051 15.6 7.6 1.1 1 0 0 1 1 1 1 Permease family AA_permease PF00324.21 ORX76302.1 - 0.007 15.0 18.9 0.023 13.3 18.9 1.7 1 1 0 1 1 1 1 Amino acid permease Renin_r PF07850.14 ORX76302.1 - 0.25 11.9 5.7 0.25 12.0 4.9 1.4 1 1 0 1 1 1 0 Renin receptor-like protein DUF1129 PF06570.11 ORX76302.1 - 1.9 7.9 8.4 2.7 7.4 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) AA_permease_2 PF13520.6 ORX76303.1 - 2.7e-55 187.9 53.1 3.5e-55 187.6 53.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX76303.1 - 6.4e-35 120.7 46.8 8.1e-35 120.3 46.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX76303.1 - 2.5e-07 30.7 8.2 2.5e-07 30.7 8.2 4.1 4 0 0 4 4 4 1 C-terminus of AA_permease NADHdh_A3 PF14987.6 ORX76303.1 - 5.8 7.3 5.2 0.86 10.0 0.5 2.0 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 AA_permease_2 PF13520.6 ORX76304.1 - 5.7e-53 180.3 44.2 7.9e-53 179.8 44.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX76304.1 - 7.4e-42 143.5 41.1 9.3e-42 143.2 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX76304.1 - 9e-09 35.3 2.8 9e-09 35.3 2.8 3.4 3 0 0 3 3 3 1 C-terminus of AA_permease AA_permease_2 PF13520.6 ORX76305.1 - 1.1e-60 205.6 45.3 1.4e-60 205.3 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX76305.1 - 7.4e-44 150.1 38.4 1e-43 149.7 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX76305.1 - 3.7e-12 46.1 5.8 4.9e-11 42.5 3.3 3.3 2 0 0 2 2 2 1 C-terminus of AA_permease DUF4131 PF13567.6 ORX76305.1 - 2.2 7.9 8.0 20 4.8 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) AA_permease_2 PF13520.6 ORX76306.1 - 2.9e-60 204.3 50.5 3.6e-60 204.0 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX76306.1 - 8.3e-46 156.6 43.9 1.1e-45 156.2 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX76306.1 - 4e-10 39.6 4.3 4e-10 39.6 4.3 3.5 3 0 0 3 3 3 1 C-terminus of AA_permease Shisa PF13908.6 ORX76306.1 - 3.2 8.0 4.4 6.7 6.9 0.4 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator zf-H2C2_2 PF13465.6 ORX76327.1 - 6.1e-17 61.2 19.9 2.7e-05 24.4 1.5 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORX76327.1 - 8.4e-16 57.5 25.7 1.1e-06 28.8 0.3 4.2 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX76327.1 - 7.7e-08 32.5 26.4 0.0069 17.1 0.3 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX76327.1 - 1.1e-05 25.6 6.4 0.0075 16.5 0.2 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon CHORD PF04968.12 ORX76327.1 - 0.0013 19.4 4.4 0.0013 19.4 4.4 2.6 2 1 0 2 2 2 1 CHORD FOXP-CC PF16159.5 ORX76327.1 - 0.0035 17.9 8.5 0.26 12.0 0.2 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX76327.1 - 0.034 14.8 11.3 0.44 11.3 3.1 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger BolA PF01722.18 ORX76327.1 - 0.1 12.9 0.3 0.1 12.9 0.3 1.7 2 0 0 2 2 2 0 BolA-like protein Wzz PF02706.15 ORX76339.1 - 0.0011 19.3 0.1 0.0016 18.7 0.1 1.2 1 0 0 1 1 1 1 Chain length determinant protein LAGLIDADG_WhiA PF14527.6 ORX76339.1 - 0.21 11.7 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Glyco_tranf_2_3 PF13641.6 ORX76340.1 - 4.4e-32 111.8 0.2 6.1e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX76340.1 - 3.3e-11 43.3 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX76340.1 - 1.6e-09 37.5 0.1 3.1e-09 36.6 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 ORX76340.1 - 7.7e-05 21.5 5.2 0.00014 20.6 5.2 1.4 1 1 0 1 1 1 1 Chitin synthase Fungal_TACC PF12709.7 ORX76341.1 - 4.4e-05 23.9 6.3 0.0054 17.1 2.5 2.7 2 0 0 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins Lzipper-MIP1 PF14389.6 ORX76341.1 - 0.00018 21.7 3.5 0.00083 19.6 3.5 2.2 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Lebercilin PF15619.6 ORX76341.1 - 0.0028 17.3 6.3 0.0054 16.4 6.3 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 ORX76341.1 - 0.0035 17.5 5.3 0.19 11.9 0.1 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 ORX76341.1 - 0.0067 16.5 6.3 0.018 15.1 6.3 1.7 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein FH2 PF02181.23 ORX76341.1 - 0.012 14.7 2.6 0.022 13.9 2.6 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF5595 PF18077.1 ORX76341.1 - 0.027 14.6 2.0 4.5 7.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF1664 PF07889.12 ORX76341.1 - 0.035 14.2 1.3 0.075 13.1 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORX76341.1 - 0.087 13.2 1.8 1 9.8 0.2 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 ORX76341.1 - 0.16 11.7 2.3 0.27 11.0 1.2 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1640 PF07798.11 ORX76341.1 - 0.33 11.0 6.4 0.59 10.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF5320 PF17253.2 ORX76341.1 - 0.37 11.9 1.6 2.5 9.2 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4200 PF13863.6 ORX76341.1 - 0.38 11.1 6.9 0.97 9.9 6.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.13 ORX76341.1 - 0.44 10.6 5.5 3.1 7.9 5.5 2.2 1 1 0 1 1 1 0 DivIVA protein Jnk-SapK_ap_N PF09744.9 ORX76341.1 - 0.62 10.3 7.9 2.1 8.5 7.9 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 ORX76341.1 - 0.74 10.3 8.6 3.7 8.1 8.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 ORX76341.1 - 0.79 9.5 7.5 1.4 8.7 1.7 2.4 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 ORX76341.1 - 1.7 8.8 8.6 1.4 9.0 0.8 3.1 3 0 0 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 ORX76341.1 - 6.1 7.0 9.9 29 4.8 9.5 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 ORX76341.1 - 6.2 7.1 7.8 3.4 7.9 2.8 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mad3_BUB1_I PF08311.12 ORX76342.1 - 6.1e-45 152.2 0.1 1e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 ORX76342.1 - 2.5e-05 24.4 0.0 4.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Fungal_trans PF04082.18 ORX76411.1 - 1.3e-39 135.8 0.7 1.3e-39 135.8 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX76411.1 - 5e-11 42.5 14.1 1.1e-10 41.5 14.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMPDH PF00478.25 ORX76430.1 - 4.4e-49 167.3 0.9 4.8e-49 167.2 0.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORX76430.1 - 4e-06 26.1 0.3 9.4e-06 24.9 0.3 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 ORX76430.1 - 1.8e-05 24.3 0.1 2.2e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ORX76430.1 - 0.0019 17.7 1.1 0.0049 16.4 0.1 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 ORX76430.1 - 0.0053 16.1 0.1 0.0074 15.6 0.1 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Methyltransf_16 PF10294.9 ORX76431.1 - 4.4e-31 107.9 0.0 6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ORX76431.1 - 0.012 16.3 0.0 0.03 15.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 ORX76431.1 - 0.061 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 ORX76431.1 - 0.061 14.1 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORX76431.1 - 0.13 12.0 0.1 0.75 9.6 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 ORX76432.1 - 1.7e-157 524.0 0.0 2e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX76432.1 - 1.5e-72 243.9 0.1 1.9e-72 243.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX76432.1 - 5.1e-06 25.8 0.0 7.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORX76432.1 - 0.00015 21.0 0.0 0.00033 19.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORX76432.1 - 0.0027 17.3 0.0 0.0063 16.1 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Glycos_transf_1 PF00534.20 ORX76435.1 - 3.1e-12 46.3 0.4 3.6e-11 42.9 0.2 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX76435.1 - 9.4e-12 45.5 0.0 4.5e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORX76435.1 - 8.3e-06 25.9 0.0 0.0046 17.0 0.0 3.3 2 1 0 2 2 2 1 Glycosyltransferase Family 4 DpaA_N PF16924.5 ORX76435.1 - 0.16 12.0 0.0 9.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain UCH PF00443.29 ORX76436.1 - 1.2e-73 247.8 0.0 1.4e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX76436.1 - 2.5e-18 66.8 0.0 8.1e-16 58.5 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORX76436.1 - 0.0022 17.5 1.4 0.085 12.3 0.7 2.9 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Csm1 PF12539.8 ORX76436.1 - 0.046 14.3 1.1 0.32 11.6 0.3 2.5 2 1 1 3 3 3 0 Chromosome segregation protein Csm1/Pcs1 DNA_pol_A_exo1 PF01612.20 ORX76437.1 - 2e-17 63.5 0.0 4.9e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Fe-S_biosyn PF01521.20 ORX76438.1 - 3.7e-21 75.4 0.1 4.3e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Gti1_Pac2 PF09729.9 ORX76439.1 - 9.1e-46 156.2 5.2 1.1e-39 136.4 0.5 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Oxysterol_BP PF01237.18 ORX76440.1 - 7.1e-66 222.5 1.2 8.1e-64 215.8 1.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein CAP PF00188.26 ORX76457.1 - 9.9e-17 62.0 0.1 1.3e-16 61.6 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Transferase PF02458.15 ORX76459.1 - 4.9e-28 97.9 0.0 7.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 ORX76459.1 - 0.092 11.4 0.0 0.21 10.2 0.0 1.5 2 0 0 2 2 2 0 Condensation domain HSP70 PF00012.20 ORX76486.1 - 1.1e-256 852.8 10.0 1.2e-256 852.6 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX76486.1 - 1.7e-18 66.6 0.5 2.4e-17 62.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 ORX76486.1 - 0.00023 21.5 2.2 0.57 10.6 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 ORX76486.1 - 0.0023 17.3 2.5 0.021 14.1 0.1 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Spore_GerAC PF05504.11 ORX76486.1 - 0.0085 16.3 8.1 0.45 10.7 0.1 3.4 3 0 0 3 3 3 2 Spore germination B3/ GerAC like, C-terminal DUF5611 PF18446.1 ORX76486.1 - 0.31 11.9 4.4 0.95 10.4 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5611) zf-C2H2_2 PF12756.7 ORX76487.1 - 6.5e-37 125.9 18.5 2.3e-31 108.1 0.6 3.6 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORX76487.1 - 9.2e-11 41.7 18.7 1.7e-09 37.7 4.2 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX76487.1 - 2.1e-07 31.1 2.2 2.1e-07 31.1 2.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX76487.1 - 0.005 16.7 3.2 0.57 10.1 0.2 2.8 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 ORX76487.1 - 0.018 15.8 15.9 0.78 10.8 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger CRA PF06589.11 ORX76487.1 - 0.024 14.7 0.8 0.059 13.5 0.8 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) zf-3CxxC_2 PF17180.4 ORX76487.1 - 0.036 14.8 1.2 0.16 12.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-binding domain DUF629 PF04780.12 ORX76487.1 - 0.055 12.0 6.6 1.2 7.6 0.9 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF629) YyzF PF14116.6 ORX76487.1 - 0.057 13.5 0.3 0.62 10.1 0.3 2.7 2 0 0 2 2 2 0 YyzF-like protein DUF1460 PF07313.12 ORX76487.1 - 0.075 12.4 1.6 0.2 11.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1460) zf-C2H2 PF00096.26 ORX76487.1 - 0.11 13.0 19.2 0.74 10.4 0.3 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.12 ORX76487.1 - 0.19 12.0 7.5 4.5 7.5 2.9 2.6 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF2024 PF09630.10 ORX76487.1 - 1.6 8.6 4.8 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) HNH_5 PF14279.6 ORX76487.1 - 1.7 8.5 9.8 2.3 8.1 0.3 3.7 4 0 0 4 4 4 0 HNH endonuclease TFIIS_C PF01096.18 ORX76487.1 - 5.4 7.0 6.0 10 6.1 0.2 3.2 4 0 0 4 4 3 0 Transcription factor S-II (TFIIS) Sec63 PF02889.16 ORX76501.1 - 6.1e-29 101.0 0.0 1.1e-27 96.9 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 ORX76501.1 - 2.3e-21 75.7 0.5 6.9e-21 74.1 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.27 ORX76502.1 - 2.4e-75 253.2 0.0 3.2e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORX76502.1 - 5.5e-08 33.3 0.0 2.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 ORX76502.1 - 0.00048 20.2 0.1 0.0078 16.2 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 ORX76502.1 - 0.11 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain COesterase PF00135.28 ORX76504.1 - 3.1e-10 39.5 0.0 5.3e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DIX PF00778.17 ORX76504.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 DIX domain RBP_receptor PF14752.6 ORX76505.1 - 3.4e-28 98.6 18.8 5.4e-22 78.1 7.5 2.4 2 1 0 2 2 2 2 Retinol binding protein receptor His_binding PF02098.16 ORX76524.1 - 0.0093 16.0 1.7 0.0093 16.0 1.7 1.7 2 0 0 2 2 2 1 Tick histamine binding protein DUF1477 PF07346.11 ORX76524.1 - 0.056 13.7 0.6 0.11 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) ABC_tran PF00005.27 ORX76527.1 - 4.2e-28 98.6 0.0 4.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX76527.1 - 2e-05 24.6 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX76527.1 - 0.0024 17.4 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ORX76527.1 - 0.0032 17.7 0.0 0.093 13.0 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 ORX76527.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 ORX76527.1 - 0.022 14.1 0.0 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ORX76527.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain DUF2620 PF10941.8 ORX76527.1 - 0.047 13.8 0.1 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF2620 AAA_29 PF13555.6 ORX76527.1 - 0.061 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX76527.1 - 0.064 13.7 0.3 0.12 12.9 0.1 1.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORX76527.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.16 ORX76528.1 - 2.1e-11 43.4 12.3 2.3e-11 43.2 12.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 ORX76528.1 - 0.031 14.1 14.0 0.052 13.4 14.0 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Lipocalin_2 PF08212.12 ORX76562.1 - 1.2e-29 103.1 0.1 1.7e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 ORX76562.1 - 6.6e-08 32.9 0.4 1.2e-07 32.1 0.4 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family AMP-binding PF00501.28 ORX76564.1 - 0 1524.9 0.0 4.8e-104 348.3 0.0 7.2 6 1 1 7 7 7 7 AMP-binding enzyme Condensation PF00668.20 ORX76564.1 - 7.7e-244 809.4 0.0 5.7e-107 358.2 0.0 4.1 4 0 0 4 4 4 4 Condensation domain AMP-binding_C PF13193.6 ORX76564.1 - 6.5e-76 251.3 20.0 1.3e-15 58.1 0.4 5.8 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX76564.1 - 4.7e-50 167.8 12.5 1.7e-11 44.3 0.1 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site Thioesterase PF00975.20 ORX76564.1 - 1.7e-33 116.7 0.0 6.4e-32 111.5 0.0 2.9 3 0 0 3 3 3 1 Thioesterase domain RHH_5 PF07878.11 ORX76564.1 - 2.8e-08 33.5 0.1 0.14 12.0 0.0 4.3 3 0 0 3 3 3 2 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF2690 PF10901.8 ORX76564.1 - 2.4e-05 24.6 0.0 6.5 7.1 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2690) Abhydrolase_1 PF00561.20 ORX76564.1 - 4.9e-05 23.1 0.1 8.4e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX76564.1 - 0.00015 22.5 3.9 0.00021 22.0 0.1 3.4 3 0 0 3 3 2 1 Alpha/beta hydrolase family HEAT_EZ PF13513.6 ORX76564.1 - 0.0037 17.8 3.4 32 5.2 0.0 5.1 4 0 0 4 4 4 0 HEAT-like repeat CopG_antitoxin PF12441.8 ORX76564.1 - 0.015 15.8 0.0 21 5.8 0.0 3.3 3 0 0 3 3 3 0 CopG antitoxin of type II toxin-antitoxin system Arc PF03869.14 ORX76564.1 - 0.062 13.1 0.3 25 4.8 0.0 3.0 3 0 0 3 3 3 0 Arc-like DNA binding domain MOZART1 PF12554.8 ORX76564.1 - 0.081 12.7 3.7 51 3.8 0.1 4.2 4 0 0 4 4 4 0 Mitotic-spindle organizing gamma-tubulin ring associated HicB PF05534.12 ORX76564.1 - 0.16 11.9 0.7 29 4.6 0.1 2.7 2 0 0 2 2 2 0 HicB family RHH_1 PF01402.21 ORX76564.1 - 0.16 12.0 0.3 39 4.4 0.0 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Pilus_CpaD PF09476.10 ORX76564.1 - 0.17 11.6 0.0 19 4.9 0.0 3.7 5 0 0 5 5 4 0 Pilus biogenesis CpaD protein (pilus_cpaD) PAS_8 PF13188.7 ORX76564.1 - 0.21 11.7 0.4 52 4.0 0.1 4.1 5 0 0 5 5 4 0 PAS domain RAG2 PF03089.14 ORX76564.1 - 0.23 10.4 6.4 48 2.8 0.0 5.8 7 0 0 7 7 7 0 Recombination activating protein 2 DJ-1_PfpI PF01965.24 ORX76585.1 - 2.8e-08 33.7 0.0 6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX76585.1 - 0.0021 17.8 0.0 0.0059 16.3 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX76585.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 1 0 1 1 1 0 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX76586.1 - 2.3e-08 34.0 0.0 8.9e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX76586.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX76586.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Latrotoxin C-terminal domain GDP_Man_Dehyd PF16363.5 ORX76615.1 - 1.7e-54 185.4 0.0 2.3e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX76615.1 - 2.9e-48 164.4 0.0 3.6e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX76615.1 - 2e-14 53.5 0.0 1.3e-13 50.8 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORX76615.1 - 2.3e-14 53.1 0.0 1.1e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORX76615.1 - 1.2e-09 37.7 0.0 2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORX76615.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX76615.1 - 1.1e-05 25.4 0.0 2.7e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 ORX76615.1 - 5.4e-05 22.5 0.1 0.3 10.2 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ORX76615.1 - 0.0063 16.1 0.1 0.34 10.4 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 ORX76615.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Isochorismatase PF00857.20 ORX76615.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Isochorismatase family NAD_binding_10 PF13460.6 ORX76615.1 - 0.025 14.5 0.0 0.071 13.0 0.0 1.8 2 1 0 2 2 2 0 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 ORX76615.1 - 0.046 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 ORX76615.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORX76615.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 ORX76615.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GalKase_gal_bdg PF10509.9 ORX76616.1 - 4.8e-21 74.1 0.1 9.7e-21 73.1 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 ORX76616.1 - 2.2e-13 50.2 1.4 4e-13 49.4 1.4 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX76616.1 - 4.1e-13 49.5 0.0 7.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transferase PF00483.23 ORX76617.1 - 1.3e-52 178.9 0.0 1.9e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORX76617.1 - 2.5e-12 46.0 7.4 9.6e-11 41.0 1.4 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORX76617.1 - 2.1e-10 41.2 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORX76617.1 - 0.0011 18.7 12.9 0.0028 17.4 2.9 3.5 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORX76617.1 - 0.028 12.6 0.2 0.038 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 ORX76617.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4253 PF14062.6 ORX76617.1 - 0.11 12.6 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) CTP_transf_3 PF02348.19 ORX76617.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4536 PF15055.6 ORX76618.1 - 9.7e-07 28.9 3.5 4.5e-06 26.8 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4536) CLASP_N PF12348.8 ORX76619.1 - 2.6e-25 89.4 0.0 3.7e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 ORX76619.1 - 0.038 14.4 0.0 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats Lipase_GDSL PF00657.22 ORX76619.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase HEAT PF02985.22 ORX76620.1 - 1.3e-12 46.8 2.8 0.99 9.8 0.0 7.5 7 0 0 7 7 7 4 HEAT repeat RTP1_C1 PF10363.9 ORX76620.1 - 1.5e-05 25.1 6.1 0.37 11.0 0.0 5.7 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 ORX76620.1 - 0.00016 21.4 1.9 0.016 14.8 0.0 3.5 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 ORX76620.1 - 0.0021 18.4 0.0 1.3 9.5 0.0 4.4 2 1 3 5 5 5 2 HEAT repeats V-ATPase_H_C PF11698.8 ORX76620.1 - 0.015 15.4 5.1 35 4.6 0.0 5.3 5 0 0 5 5 5 0 V-ATPase subunit H Cohesin_HEAT PF12765.7 ORX76620.1 - 0.1 12.9 0.4 34 4.9 0.1 3.9 3 1 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.7 ORX76620.1 - 1.5 8.8 13.4 0.24 11.3 0.1 4.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Aquarius_N PF16399.5 ORX76621.1 - 1.7e-210 701.1 3.4 2.2e-210 700.8 3.4 1.0 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus HGTP_anticodon PF03129.20 ORX76710.1 - 3.3e-23 81.7 0.2 6.3e-23 80.7 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORX76710.1 - 6.2e-06 26.3 0.0 2.8e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) CRAL_TRIO PF00650.20 ORX76711.1 - 8.3e-38 129.6 0.0 1.3e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX76711.1 - 3.5e-14 52.7 0.2 1e-13 51.2 0.2 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORX76711.1 - 8.2e-06 26.0 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3472 PF11958.8 ORX76725.1 - 1.4e-14 54.9 1.1 2.1e-14 54.4 1.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX76725.1 - 0.0013 18.7 0.2 0.0021 18.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) PRiA4_ORF3 PF07929.11 ORX76725.1 - 0.1 12.3 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein CBM_19 PF03427.13 ORX76726.1 - 0.013 15.4 13.9 0.074 13.1 3.6 3.0 2 1 0 2 2 2 0 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX76726.1 - 0.027 14.6 12.6 0.59 10.3 1.6 3.5 2 2 1 3 3 3 0 Chitin binding Peritrophin-A domain Forkhead PF00250.18 ORX76727.1 - 6.1e-35 119.4 0.0 1e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain A_deamin PF02137.18 ORX76728.1 - 2.2e-75 254.1 0.0 2.7e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF4335 PF14233.6 ORX76729.1 - 0.0044 17.0 2.0 0.13 12.2 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4335) ADIP PF11559.8 ORX76762.1 - 0.00099 19.2 21.7 0.0015 18.7 6.1 10.9 4 3 6 11 11 11 3 Afadin- and alpha -actinin-Binding HALZ PF02183.18 ORX76762.1 - 0.0044 17.2 1.7 0.0044 17.2 1.7 13.5 13 2 2 15 15 15 3 Homeobox associated leucine zipper FemAB PF02388.16 ORX76762.1 - 0.0055 15.6 2.9 0.0055 15.6 2.9 5.6 4 2 4 8 8 8 1 FemAB family KASH_CCD PF14662.6 ORX76762.1 - 0.12 12.2 0.1 0.12 12.2 0.1 8.4 4 3 5 9 9 9 0 Coiled-coil region of CCDC155 or KASH DUF2433 PF10360.9 ORX76762.1 - 0.98 9.5 4.0 1.8 8.7 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2433) E1-E2_ATPase PF00122.20 ORX76780.1 - 2.1e-35 121.9 2.5 6.1e-35 120.4 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORX76780.1 - 4.6e-21 76.1 0.2 1.6e-17 64.5 0.2 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX76780.1 - 1.8e-19 70.2 5.8 1.8e-19 70.2 5.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 ORX76780.1 - 3e-12 46.0 0.0 9.3e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX76780.1 - 0.00054 19.8 0.4 0.44 10.2 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.24 ORX76780.1 - 0.067 13.0 6.5 1.9 8.2 0.4 2.8 3 0 0 3 3 3 0 Fatty acid desaturase Methyltransf_16 PF10294.9 ORX76781.1 - 7.7e-16 58.3 0.2 1.5e-13 50.9 0.0 2.4 1 1 1 2 2 2 2 Lysine methyltransferase MTS PF05175.14 ORX76781.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX76781.1 - 1.2e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORX76781.1 - 5.5e-06 27.0 0.0 1.5e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX76781.1 - 0.00057 19.7 0.2 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX76781.1 - 0.0086 15.7 0.0 0.019 14.6 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 ORX76781.1 - 0.0093 16.6 0.0 0.024 15.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX76781.1 - 0.023 15.4 0.1 0.065 14.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORX76781.1 - 0.03 14.1 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Enamelin PF15362.6 ORX76781.1 - 0.083 11.2 0.3 0.12 10.7 0.3 1.1 1 0 0 1 1 1 0 Enamelin Methyltransf_23 PF13489.6 ORX76781.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CutA1 PF03091.15 ORX76782.1 - 1.1e-38 131.1 0.3 1.2e-38 130.9 0.3 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Pox_vIL-18BP PF05566.12 ORX76782.1 - 0.04 14.2 0.1 0.052 13.8 0.1 1.5 1 1 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein TMV_coat PF00721.21 ORX76782.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) Pkinase PF00069.25 ORX76783.1 - 8.4e-49 166.3 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX76783.1 - 1.1e-23 83.8 0.0 1.6e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX76783.1 - 0.00018 21.5 0.0 0.002 18.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX76783.1 - 0.002 17.5 0.0 0.0038 16.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORX76783.1 - 0.013 15.0 0.4 0.48 10.0 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 ORX76783.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX76783.1 - 0.096 11.6 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 ORX76783.1 - 0.11 12.1 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Gti1_Pac2 PF09729.9 ORX76798.1 - 6.4e-39 133.9 6.5 8.5e-36 123.7 0.5 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family Myticin-prepro PF10690.9 ORX76799.1 - 0.0037 17.5 0.3 0.0056 16.9 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Phage_lysozyme PF00959.19 ORX76865.1 - 1.2e-12 48.2 0.1 1.6e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Phage lysozyme GHMP_kinases_C PF08544.13 ORX76868.1 - 0.057 13.8 0.0 5.3 7.5 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DUF4418 PF14387.6 ORX76868.1 - 0.14 12.4 1.4 3.2 8.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Dynactin_p62 PF05502.13 ORX76868.1 - 2.9 6.6 9.2 2.2 7.0 1.0 2.3 1 1 0 2 2 2 0 Dynactin p62 family PSI_integrin PF17205.3 ORX76868.1 - 3.4 7.5 10.4 8.1 6.3 1.6 2.3 2 0 0 2 2 2 0 Integrin plexin domain FPN1 PF06963.12 ORX76890.1 - 5.3e-104 348.2 17.7 6.2e-104 348.0 17.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) OB_Dis3 PF17849.1 ORX76891.1 - 2e-24 85.4 0.0 3.1e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) RNB PF00773.19 ORX76891.1 - 4.9e-05 22.8 1.0 8.3e-05 22.1 0.6 1.6 2 0 0 2 2 2 1 RNB domain CSD2 PF17876.1 ORX76891.1 - 0.00054 20.1 0.0 0.00095 19.3 0.0 1.4 1 0 0 1 1 1 1 Cold shock domain PLA2G12 PF06951.11 ORX76925.1 - 1.1e-05 25.4 13.8 2.5e-05 24.3 13.8 1.7 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) EF-hand_12 PF17901.1 ORX76925.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 EF-hand fold domain Arrestin_N PF00339.29 ORX76926.1 - 2.4e-12 47.1 1.9 2e-09 37.7 0.1 3.3 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX76926.1 - 1.9e-11 44.6 1.8 7.1e-08 33.0 0.9 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX76926.1 - 0.0022 17.7 0.0 0.0053 16.5 0.0 1.7 1 1 0 1 1 1 1 Arrestin_N terminal like Spo0M PF07070.11 ORX76926.1 - 0.038 13.5 0.0 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 SpoOM protein DUF4502 PF14950.6 ORX76927.1 - 4.9e-08 32.8 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) CDP-OH_P_transf PF01066.21 ORX76928.1 - 1.2e-17 64.4 0.1 1.2e-17 64.4 0.1 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TFIIS_C PF01096.18 ORX76929.1 - 2.3e-17 62.6 1.8 2.3e-17 62.6 1.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORX76929.1 - 7.1e-06 25.8 12.9 0.0019 18.0 1.0 3.3 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 ORX76929.1 - 0.0069 15.9 14.0 0.068 12.7 1.1 3.4 2 2 1 3 3 3 3 TFIIB zinc-binding DZR PF12773.7 ORX76929.1 - 0.007 16.4 11.9 8.6 6.5 11.9 3.3 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 ORX76929.1 - 0.024 15.0 9.6 0.026 14.9 0.9 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar Prok-RING_1 PF14446.6 ORX76929.1 - 0.041 13.8 9.7 0.12 12.4 1.1 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-TFIIB PF13453.6 ORX76929.1 - 0.048 13.0 0.9 0.048 13.0 0.9 2.0 2 1 0 2 2 2 0 Transcription factor zinc-finger PNP_UDP_1 PF01048.20 ORX76929.1 - 0.054 12.7 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphorylase superfamily Ogr_Delta PF04606.12 ORX76929.1 - 0.057 13.4 1.5 0.057 13.4 1.5 2.1 2 0 0 2 2 1 0 Ogr/Delta-like zinc finger HypA PF01155.19 ORX76929.1 - 0.075 13.1 7.0 89 3.2 7.0 3.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_LEF5_C PF11792.8 ORX76929.1 - 0.078 12.7 0.1 0.078 12.7 0.1 3.0 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain eIF-5_eIF-2B PF01873.17 ORX76929.1 - 0.095 12.6 0.4 0.095 12.6 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 tRNA-synt_1f PF01921.18 ORX76929.1 - 0.13 11.1 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) zf-RRN7 PF11781.8 ORX76929.1 - 0.14 11.9 5.8 15 5.4 1.9 4.0 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nop10p PF04135.12 ORX76929.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.4 2 1 1 3 3 2 0 Nucleolar RNA-binding protein, Nop10p family C1_1 PF00130.22 ORX76929.1 - 0.22 11.5 6.9 1.1 9.1 0.9 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 ORX76929.1 - 0.24 11.5 14.6 2 8.6 0.3 4.1 4 0 0 4 4 4 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 ORX76929.1 - 0.25 11.1 15.2 0.36 10.6 3.0 3.7 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 ORX76929.1 - 0.3 11.6 6.1 0.57 10.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain MqsA_antitoxin PF15731.5 ORX76929.1 - 0.3 11.2 2.2 6.6 6.9 0.5 2.2 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Zn_ribbon_recom PF13408.6 ORX76929.1 - 0.35 11.4 13.9 2.3 8.8 1.7 3.4 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.6 ORX76929.1 - 0.51 10.3 11.8 5.9 6.9 1.6 3.9 2 2 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 ORX76929.1 - 0.54 9.7 20.6 0.34 10.4 0.4 4.3 4 1 0 4 4 4 0 zinc-ribbon domain RPA_interact_C PF14768.6 ORX76929.1 - 0.6 10.7 7.3 4.6 7.9 7.3 2.2 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Mu-like_Com PF10122.9 ORX76929.1 - 0.74 9.3 0.1 0.74 9.3 0.1 2.9 3 1 0 3 3 3 0 Mu-like prophage protein Com zf-C3HC4_3 PF13920.6 ORX76929.1 - 1.1 9.2 8.6 1.6 8.6 1.2 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.13 ORX76929.1 - 1.1 9.3 11.5 0.23 11.5 2.5 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 ORX76929.1 - 1.6 8.7 7.6 18 5.3 2.6 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.13 ORX76929.1 - 1.6 8.5 16.3 6 6.6 3.9 3.9 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 ORX76929.1 - 2 8.2 23.6 2.3 8.0 0.1 4.1 4 1 0 4 4 3 0 zinc-ribbon domain DUF3268 PF11672.8 ORX76929.1 - 2.3 8.6 6.4 0.65 10.3 1.1 2.2 2 1 0 2 2 2 0 zinc-finger-containing domain zf_C2H2_10 PF18414.1 ORX76929.1 - 3 7.5 5.1 9.7 5.8 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger zf_UBZ PF18439.1 ORX76929.1 - 3.3 7.4 8.2 36 4.1 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-HYPF PF07503.12 ORX76929.1 - 3.9 7.3 11.5 1.1 9.1 0.1 3.8 4 0 0 4 4 4 0 HypF finger zf-CSL PF05207.13 ORX76929.1 - 4.9 7.0 9.9 2.4 7.9 1.8 2.9 2 2 0 2 2 2 0 CSL zinc finger Zn_ribbon_SprT PF17283.2 ORX76929.1 - 6.1 6.8 9.9 11 6.1 0.9 3.8 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 ORX76929.1 - 6.5 6.9 13.7 5.1 7.3 0.2 3.3 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 PhnA_Zn_Ribbon PF08274.12 ORX76929.1 - 8 6.5 12.3 12 6.0 0.4 3.9 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 ORX76929.1 - 8.4 6.5 8.6 1.8 8.6 2.2 2.9 3 1 0 3 3 3 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 ORX76929.1 - 9.8 6.1 15.6 0.25 11.2 4.8 3.4 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger RNA_polI_A34 PF08208.11 ORX76930.1 - 3.2e-27 96.0 3.6 3.8e-27 95.7 3.6 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DPBB_1 PF03330.18 ORX76948.1 - 4.2e-10 39.8 0.1 8.3e-10 38.8 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX76948.1 - 8.9e-07 28.8 0.2 1.6e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 ORX76948.1 - 0.013 15.6 0.5 0.03 14.4 0.1 1.7 1 1 1 2 2 2 0 Cerato-platanin V_ATPase_I PF01496.19 ORX76949.1 - 3.1e-286 951.6 0.0 3.5e-286 951.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF5344 PF17279.2 ORX76949.1 - 0.025 15.1 1.2 3.4 8.3 2.5 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5344) Cortex-I_coil PF09304.10 ORX76949.1 - 0.19 12.0 1.2 0.33 11.2 0.2 1.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil adh_short PF00106.25 ORX76950.1 - 1.7e-28 99.4 0.0 2.3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX76950.1 - 2.2e-12 47.0 0.0 2.8e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ORX76950.1 - 9.9e-05 21.8 0.2 0.0018 17.7 0.2 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 ORX76950.1 - 0.23 10.8 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP-synt_ab PF00006.25 ORX76951.1 - 7.8e-62 208.7 0.0 1.2e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX76951.1 - 1.2e-22 80.2 0.8 2.7e-22 79.1 0.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ORX76951.1 - 0.014 14.7 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ORX76951.1 - 0.019 14.2 0.6 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 ORX76951.1 - 0.049 14.0 0.7 0.45 10.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORX76951.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORX76951.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORX76951.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Med2 PF11214.8 ORX76951.1 - 0.13 12.4 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 RNA_helicase PF00910.22 ORX76951.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Chitin_synth_2 PF03142.15 ORX76952.1 - 3.7e-247 821.1 1.3 5.1e-247 820.7 1.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX76952.1 - 1.3e-12 48.1 0.0 5.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX76952.1 - 3.2e-12 46.8 7.1 3.2e-12 46.8 7.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX76952.1 - 0.002 17.6 0.1 0.73 9.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX76952.1 - 0.0029 17.4 0.0 0.092 12.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 TP_methylase PF00590.20 ORX76952.1 - 0.2 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Kelch_5 PF13854.6 ORX76953.1 - 3.3e-23 81.2 1.4 9.5e-05 22.3 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ORX76953.1 - 7e-20 70.8 7.4 0.0006 20.0 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX76953.1 - 3.2e-17 62.2 9.4 0.00028 21.1 0.0 7.3 5 2 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 ORX76953.1 - 5.9e-13 48.6 3.2 0.0024 17.9 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORX76953.1 - 2e-12 46.5 5.3 0.024 14.6 0.0 7.1 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORX76953.1 - 6.7e-10 38.4 11.1 0.05 13.2 0.2 7.0 7 0 0 7 7 7 4 Kelch motif Tweety PF04906.13 ORX76953.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Tweety AAA_18 PF13238.6 ORX76954.1 - 3.3e-10 40.6 0.0 3.1e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ORX76954.1 - 9.2e-06 25.5 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase PRK PF00485.18 ORX76954.1 - 0.00034 20.4 0.1 0.0015 18.3 0.1 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 ORX76954.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 ORX76954.1 - 0.0016 18.6 0.0 0.006 16.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX76954.1 - 0.0041 17.4 0.0 0.0096 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX76954.1 - 0.022 15.1 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 ORX76954.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ORX76954.1 - 0.036 13.8 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORX76954.1 - 0.04 13.2 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 ORX76954.1 - 0.069 13.0 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase CoaE PF01121.20 ORX76954.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Cofilin_ADF PF00241.20 ORX76955.1 - 3.8e-40 136.5 0.6 4.3e-40 136.3 0.6 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein pKID PF02173.17 ORX77015.1 - 0.0038 16.6 0.5 0.0079 15.6 0.5 1.5 1 0 0 1 1 1 1 pKID domain GRP PF07172.11 ORX77019.1 - 5.2 7.8 22.1 8.4 7.2 22.1 1.6 1 1 0 1 1 1 0 Glycine rich protein family GRP PF07172.11 ORX77020.1 - 2.1 9.1 12.8 2.2 9.0 12.8 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF5553 PF17707.1 ORX77021.1 - 0.16 11.4 0.3 0.15 11.4 0.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5553) DUF4179 PF13786.6 ORX77023.1 - 0.1 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Moricin PF06451.11 ORX77024.1 - 0.085 12.6 4.6 65 3.4 0.0 4.5 2 2 2 4 4 4 0 Moricin GBP_PSP PF02425.15 ORX77024.1 - 0.11 12.2 6.7 88 2.9 0.2 5.0 2 2 3 5 5 5 0 Paralytic/GBP/PSP peptide CsoS2_M PF12288.8 ORX77024.1 - 4.4 6.6 11.9 12 5.1 1.3 2.8 1 1 2 3 3 3 0 Carboxysome shell peptide mid-region CBM_26 PF16824.5 ORX77025.1 - 0.0099 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 C-terminal carbohydrate-binding module Homeodomain PF00046.29 ORX77040.1 - 6.1e-18 64.4 3.9 6.6e-18 64.3 3.9 1.0 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 ORX77040.1 - 0.0027 17.5 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 ORX77040.1 - 0.0098 15.8 0.5 0.016 15.1 0.1 1.5 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 ORX77040.1 - 0.01 15.6 0.0 0.063 13.1 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 ORX77040.1 - 0.062 13.4 0.1 4.2 7.6 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain RQC PF09382.10 ORX77041.1 - 2.2e-23 82.2 0.5 7.5e-23 80.5 0.5 2.0 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 ORX77041.1 - 4.5e-22 78.7 0.0 1.3e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX77041.1 - 1.4e-20 73.7 0.1 9.4e-19 67.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORX77041.1 - 1.3e-17 64.3 6.7 5.8e-17 62.2 6.7 2.2 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 ORX77041.1 - 1.7e-13 50.3 0.0 3.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 ORX77041.1 - 4.6e-06 26.7 0.1 2.5e-05 24.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HHH PF00633.23 ORX77041.1 - 0.088 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif CN_hydrolase PF00795.22 ORX77063.1 - 6.5e-29 101.1 0.0 7.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_M28 PF04389.17 ORX77064.1 - 3.1e-18 66.2 0.0 4.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 ORX77064.1 - 0.028 13.9 0.1 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 Nicastrin Mt_ATP-synt_B PF05405.14 ORX77065.1 - 0.0084 15.7 0.4 0.01 15.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Condensation PF00668.20 ORX77065.1 - 0.028 13.1 2.8 0.032 12.9 2.8 1.0 1 0 0 1 1 1 0 Condensation domain PRiA4_ORF3 PF07929.11 ORX77066.1 - 5.6e-06 26.2 0.1 1.4e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF3759 PF12585.8 ORX77067.1 - 1.8e-36 124.0 7.7 2.1e-36 123.8 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Tyrosinase PF00264.20 ORX77068.1 - 2e-35 123.1 5.0 9.1e-34 117.7 5.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase WD40 PF00400.32 ORX77069.1 - 6.2e-16 58.5 6.0 0.0048 17.7 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX77069.1 - 4.1e-11 43.0 0.0 0.00021 21.5 0.0 4.0 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX77069.1 - 0.00015 21.2 2.0 0.0045 16.4 0.2 2.5 1 1 2 3 3 3 2 WD40-like domain CDC45 PF02724.14 ORX77069.1 - 0.045 12.0 4.1 0.059 11.7 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PHTB1_N PF14727.6 ORX77069.1 - 0.13 11.6 0.9 9.9 5.4 0.1 2.9 3 1 0 3 3 3 0 PTHB1 N-terminus Utp8 PF10395.9 ORX77069.1 - 0.29 9.6 0.0 0.29 9.6 0.0 2.1 3 0 0 3 3 3 0 Utp8 family RNA_polI_A34 PF08208.11 ORX77069.1 - 0.56 10.3 11.0 1.1 9.3 11.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 ORX77069.1 - 1.3 9.1 14.9 2 8.5 14.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Sec62 PF03839.16 ORX77069.1 - 7.5 6.0 6.3 12 5.3 6.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Mito_carr PF00153.27 ORX77070.1 - 8.9e-66 217.9 2.4 6.9e-21 74.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PALP PF00291.25 ORX77071.1 - 4.3e-81 272.5 0.3 5.5e-81 272.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ORX77071.1 - 1.1e-43 146.9 0.0 2.3e-25 88.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase N_BRCA1_IG PF16158.5 ORX77071.1 - 0.041 14.6 0.0 0.097 13.4 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene Serglycin PF04360.12 ORX77072.1 - 0.15 12.0 0.0 22 5.0 0.0 2.2 2 0 0 2 2 2 0 Serglycin ADIP PF11559.8 ORX77073.1 - 0.0082 16.2 4.3 0.0082 16.2 4.3 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding STELLO PF03385.17 ORX77073.1 - 0.071 11.9 4.6 0.039 12.8 2.2 1.7 2 0 0 2 2 2 0 STELLO glycosyltransferases Prefoldin_2 PF01920.20 ORX77074.1 - 5e-27 93.9 5.0 5.6e-27 93.8 5.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Occludin_ELL PF07303.13 ORX77074.1 - 0.012 16.4 1.5 1.2 9.9 0.2 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF1488 PF07369.11 ORX77074.1 - 0.065 13.2 0.0 7.2 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) Tup_N PF08581.10 ORX77074.1 - 0.074 13.4 4.2 0.12 12.7 1.0 2.1 2 0 0 2 2 2 0 Tup N-terminal IFRD PF05004.13 ORX77075.1 - 6.8e-64 215.9 8.8 8.9e-64 215.5 8.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 ORX77075.1 - 0.0016 18.8 0.1 7.5 7.0 0.0 3.6 1 1 2 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 ORX77075.1 - 0.0019 16.9 2.2 0.011 14.3 0.6 2.2 1 1 2 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 ORX77075.1 - 0.0022 18.1 0.2 4.9 7.7 0.0 3.0 2 0 0 2 2 2 2 HEAT repeat IFRD_C PF04836.12 ORX77075.1 - 0.0044 17.6 2.4 0.03 14.9 0.1 3.1 2 1 0 2 2 2 1 Interferon-related protein conserved region FliH PF02108.16 ORX77075.1 - 0.0061 16.6 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Flagellar assembly protein FliH CLASP_N PF12348.8 ORX77075.1 - 0.076 12.6 3.7 1.4 8.4 1.3 2.3 1 1 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 ORX77075.1 - 0.095 13.2 0.3 1.5 9.4 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat MitMem_reg PF13012.6 ORX77076.1 - 0.00019 21.8 0.1 0.0002 21.7 0.1 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Pkinase PF00069.25 ORX77097.1 - 6.1e-66 222.5 0.0 8.5e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX77097.1 - 9.7e-30 103.7 0.0 1.6e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORX77097.1 - 1.3e-10 41.7 0.5 3.8e-10 40.3 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain PX PF00787.24 ORX77097.1 - 2e-07 31.0 1.6 3.5e-07 30.2 0.7 2.0 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 ORX77097.1 - 7.3e-05 22.2 0.0 0.00019 20.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORX77097.1 - 0.00042 19.7 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX77097.1 - 0.00051 18.9 0.0 0.00099 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX77097.1 - 0.0011 18.0 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORX77097.1 - 0.0012 18.5 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORX77097.1 - 0.18 11.7 0.9 0.59 10.0 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Glyco_trans_1_3 PF13528.6 ORX77098.1 - 3.9e-06 26.4 0.0 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Sterol_MT_C PF08498.10 ORX77099.1 - 1.1e-21 76.9 0.1 1.9e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ORX77099.1 - 1.6e-19 70.4 0.0 9.7e-19 67.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX77099.1 - 2.4e-16 60.2 0.0 8.9e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX77099.1 - 6.6e-16 58.5 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX77099.1 - 3.2e-12 46.3 0.0 4.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORX77099.1 - 4.3e-12 46.2 0.0 7.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX77099.1 - 5.1e-09 36.8 0.0 1.7e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX77099.1 - 6.6e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 ORX77099.1 - 0.00012 21.5 0.3 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB MetW PF07021.12 ORX77099.1 - 0.004 16.8 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 ORX77099.1 - 0.043 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 ORX77099.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 ORX77099.1 - 0.075 12.6 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Gln-synt_C-ter PF18318.1 ORX77139.1 - 3.4e-36 123.7 0.5 7.8e-36 122.5 0.5 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORX77139.1 - 1e-18 67.5 0.6 3.5e-18 65.7 0.1 2.1 3 0 0 3 3 3 1 Glutamine synthetase, catalytic domain Cytochrom_B562 PF07361.11 ORX77139.1 - 0.058 14.0 0.3 0.19 12.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome b562 FAD_binding_7 PF03441.14 ORX77140.1 - 9.5e-61 204.8 2.3 9.5e-61 204.8 2.3 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORX77140.1 - 2.4e-30 105.7 0.0 4.9e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DAHP_synth_1 PF00793.20 ORX77192.1 - 1.4e-98 329.1 0.0 1.8e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CBM9_1 PF06452.11 ORX77193.1 - 3.8e-08 33.5 0.4 8.2e-08 32.4 0.4 1.5 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like EamA PF00892.20 ORX77194.1 - 2e-30 105.7 25.3 8.6e-16 58.4 12.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 ORX77194.1 - 0.021 14.3 0.3 0.067 12.7 0.0 1.9 3 0 0 3 3 3 0 Solute carrier family 35 Arrestin_N PF00339.29 ORX77195.1 - 5.5e-08 33.0 0.2 4.4e-07 30.1 0.2 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX77195.1 - 9.7e-07 29.3 0.3 0.00091 19.7 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORX77195.1 - 0.055 12.6 0.1 0.098 11.8 0.1 1.4 1 0 0 1 1 1 0 Rgp1 Ribosomal_L36e PF01158.18 ORX77196.1 - 3.1e-42 142.7 6.9 3.5e-42 142.6 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mago-bind PF09282.10 ORX77196.1 - 0.21 11.5 1.7 7.4 6.5 0.2 2.7 2 0 0 2 2 2 0 Mago binding Creatinase_N_2 PF16189.5 ORX77197.1 - 4.2e-57 192.8 0.7 1.2e-56 191.2 1.1 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORX77197.1 - 2.3e-46 158.1 0.0 4.8e-46 157.1 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ORX77197.1 - 2.1e-22 78.9 2.5 1.4e-21 76.3 0.3 3.0 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ORX77197.1 - 1.1e-17 64.9 0.1 5.5e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF5420 PF17457.2 ORX77197.1 - 0.099 12.5 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5420) DUF2433 PF10360.9 ORX77198.1 - 5.9e-10 39.3 1.0 6.2e-08 32.8 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 ORX77198.1 - 4.3e-07 29.6 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.6 ORX77217.1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX77217.1 - 0.00041 21.0 0.0 0.001 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX77217.1 - 0.071 13.8 0.0 0.25 12.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Ammonium_transp PF00909.21 ORX77219.1 - 1.4e-105 353.3 29.8 1.9e-105 352.8 29.8 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_5_2 PF16079.5 ORX77219.1 - 2.7 8.4 7.5 14 6.1 2.0 3.3 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Ammonium_transp PF00909.21 ORX77220.1 - 1.9e-106 356.1 29.7 2.2e-106 355.9 29.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Rieske PF00355.26 ORX77221.1 - 7.2e-09 35.5 0.0 1.8e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain TFIIS_M PF07500.14 ORX77222.1 - 2.9e-27 95.3 5.9 3.4e-27 95.2 5.9 1.0 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain KIX_2 PF16987.5 ORX77222.1 - 1.3e-05 25.0 1.1 2.4e-05 24.2 1.1 1.4 1 0 0 1 1 1 1 KIX domain Pkinase PF00069.25 ORX77299.1 - 6.5e-76 255.2 0.0 8.2e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX77299.1 - 1.8e-50 171.7 0.0 2.5e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX77299.1 - 1.4e-20 73.4 1.2 1.9e-20 73.0 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 ORX77299.1 - 6.2e-08 32.3 0.0 8.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX77299.1 - 2.2e-06 26.8 0.0 3.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX77299.1 - 0.002 18.1 0.0 0.016 15.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX77299.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORX77299.1 - 0.15 11.4 0.3 0.65 9.3 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S28e PF01200.18 ORX77300.1 - 3e-33 113.6 1.2 3.6e-33 113.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORX77300.1 - 0.069 13.5 0.0 0.099 13.0 0.0 1.3 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORX77300.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region Ribosomal_S4e PF00900.20 ORX77301.1 - 3.5e-36 123.0 0.1 7.1e-36 122.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX77301.1 - 2.2e-26 91.2 0.1 3.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORX77301.1 - 2.8e-21 75.3 6.6 6.5e-21 74.2 6.6 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORX77301.1 - 1.3e-08 34.4 0.1 3.3e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORX77301.1 - 7.1e-05 22.6 4.5 7.1e-05 22.6 4.5 2.6 3 0 0 3 3 3 1 KOW motif Kinesin PF00225.23 ORX77302.1 - 4.2e-114 381.0 2.0 4.2e-114 381.0 2.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORX77302.1 - 7.4e-28 97.4 0.2 7.4e-28 97.4 0.2 4.0 3 1 1 4 4 4 1 Microtubule binding Tropomyosin PF00261.20 ORX77302.1 - 9.8e-05 21.8 36.6 0.0018 17.7 21.9 3.0 2 0 0 2 2 2 2 Tropomyosin AAA PF00004.29 ORX77302.1 - 0.055 13.9 0.3 18 5.8 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORX77302.1 - 0.063 12.8 0.0 0.063 12.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 ORX77302.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.3 2 1 2 4 4 4 0 AAA domain AAA_16 PF13191.6 ORX77302.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.8 2 1 1 3 3 3 0 AAA ATPase domain NPV_P10 PF05531.12 ORX77302.1 - 2.3 8.8 18.6 18 5.9 7.9 4.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein F-box-like PF12937.7 ORX77334.1 - 0.0031 17.4 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 ORX77334.1 - 0.0054 16.3 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box Ribosomal_60s PF00428.19 ORX77335.1 - 9.5e-28 96.6 8.6 1.1e-27 96.4 8.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 ORX77335.1 - 0.097 13.1 0.8 0.15 12.5 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) ELP6 PF09807.9 ORX77336.1 - 1.1e-45 156.1 0.0 1.3e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 ORX77336.1 - 0.078 12.3 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 KaiC Ras PF00071.22 ORX77354.1 - 2.1e-25 89.2 0.0 3e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX77354.1 - 7.9e-10 39.0 0.0 1.9e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 ORX77355.1 - 3.5e-48 164.3 0.0 4.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX77355.1 - 3.5e-24 85.5 0.0 4.1e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX77355.1 - 1.2e-05 25.3 0.0 0.0034 17.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX77355.1 - 0.00014 21.3 0.0 0.0027 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PIP49_C PF12260.8 ORX77355.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase PF00069.25 ORX77356.1 - 7.3e-65 218.9 0.1 8.8e-65 218.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX77356.1 - 4.7e-19 68.7 0.0 6.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX77356.1 - 4.7e-09 36.5 0.0 4.6e-06 26.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX77356.1 - 0.0069 15.2 0.0 0.015 14.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 ORX77356.1 - 0.022 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 ORX77356.1 - 0.022 14.1 0.2 0.038 13.3 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G-patch PF01585.23 ORX77357.1 - 3.5e-13 49.2 1.4 3.5e-13 49.2 1.4 1.8 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 ORX77357.1 - 0.00014 21.6 0.1 0.00025 20.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 ORX77357.1 - 0.00017 21.6 0.5 0.0005 20.1 0.5 1.8 1 0 0 1 1 1 1 G-patch domain WH1 PF00568.23 ORX77358.1 - 1.1e-17 63.9 0.0 1.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORX77358.1 - 1.6e-13 50.7 0.0 4.6e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 ORX77358.1 - 0.0018 18.1 0.8 0.29 11.0 0.2 2.6 2 0 0 2 2 2 2 WH2 motif SH3_9 PF14604.6 ORX77398.1 - 4.9e-13 48.7 0.2 4.9e-13 48.7 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 ORX77398.1 - 6.8e-13 48.0 0.0 1.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX77398.1 - 8.7e-09 34.9 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF872 PF05915.12 ORX77399.1 - 3.8e-12 46.4 2.0 5.1e-12 46.0 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF308 PF03729.13 ORX77399.1 - 0.0022 18.3 2.5 0.0031 17.8 2.5 1.2 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) Tetraspanin PF00335.20 ORX77399.1 - 0.1 12.3 0.9 0.13 12.0 0.9 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 ORX77399.1 - 0.15 11.7 0.7 0.18 11.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YrhK PF14145.6 ORX77399.1 - 0.2 11.5 3.1 4.4 7.3 0.0 2.2 1 1 0 2 2 2 0 YrhK-like protein DUF3040 PF11239.8 ORX77399.1 - 0.32 11.3 2.8 0.71 10.2 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) CCDC-167 PF15188.6 ORX77400.1 - 0.001 19.3 1.4 0.0026 18.1 1.4 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 ArfGap PF01412.18 ORX77400.1 - 0.095 12.8 2.8 0.25 11.4 2.1 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Med9 PF07544.13 ORX77400.1 - 0.23 11.6 5.0 0.68 10.1 1.1 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 ORX77400.1 - 0.7 10.1 4.7 0.51 10.5 1.3 2.3 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 ORX77400.1 - 2.1 8.7 11.7 0.22 11.9 3.2 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 ORX77400.1 - 6.1 7.0 11.9 6.7 6.9 6.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Lig_chan PF00060.26 ORX77401.1 - 0.14 12.0 0.4 0.18 11.6 0.4 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel FXR_C1 PF16096.5 ORX77402.1 - 1.3 9.3 11.8 4.5 7.6 6.3 2.2 1 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Chitin_synth_2 PF03142.15 ORX77462.1 - 4.2e-258 857.3 0.3 5.1e-258 857.0 0.3 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX77462.1 - 2.5e-11 43.9 13.9 1.2e-10 41.7 13.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX77462.1 - 6.5e-11 42.5 0.0 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX77462.1 - 3e-06 26.8 0.1 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX77462.1 - 0.00063 19.6 0.0 0.076 12.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Man-6-P_recep PF02157.15 ORX77463.1 - 2.4e-24 85.8 0.0 2.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 ORX77463.1 - 2.1e-18 66.8 0.1 7.3e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 ORX77463.1 - 1.8e-14 54.2 0.0 3.7e-14 53.2 0.0 1.4 1 1 1 2 2 2 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 ORX77463.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein PMP1_2 PF08114.11 ORX77463.1 - 0.053 13.3 2.6 0.083 12.6 2.6 1.3 1 0 0 1 1 1 0 ATPase proteolipid family TPR_1 PF00515.28 ORX77464.1 - 3.5e-23 80.4 4.2 1.4e-05 24.7 0.2 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORX77464.1 - 1.6e-16 59.0 7.9 0.00011 22.0 0.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX77464.1 - 1.7e-15 56.4 13.2 0.00021 20.9 0.3 5.6 3 2 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 ORX77464.1 - 2.1e-14 52.8 5.4 0.0019 18.5 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX77464.1 - 4.5e-12 45.2 9.6 0.0055 16.8 0.1 6.2 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX77464.1 - 1.2e-10 41.2 5.9 0.041 14.7 0.0 6.3 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORX77464.1 - 1.5e-10 41.5 7.9 9.3e-06 26.1 0.2 4.8 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX77464.1 - 1.9e-10 41.2 1.7 0.0065 17.1 0.1 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX77464.1 - 2.3e-09 37.4 6.4 0.00021 21.5 1.3 4.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 ORX77464.1 - 3.5e-09 36.9 1.2 0.0056 17.0 0.1 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX77464.1 - 2.1e-07 31.0 0.7 0.0017 18.5 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORX77464.1 - 7.4e-07 28.8 4.0 0.012 15.6 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX77464.1 - 6.4e-06 26.3 7.9 0.00075 19.7 2.5 2.9 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF1641 PF07849.11 ORX77464.1 - 2.8e-05 23.9 0.1 0.0023 17.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1641) TPR_4 PF07721.14 ORX77464.1 - 0.013 16.0 0.0 0.041 14.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX77464.1 - 0.025 15.2 1.6 4.1 8.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5578 PF17741.1 ORX77464.1 - 0.054 12.9 0.1 0.41 10.0 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Octopine_DH PF02317.17 ORX77464.1 - 0.075 13.1 0.1 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain TPR_10 PF13374.6 ORX77464.1 - 0.62 10.0 7.4 0.35 10.8 0.8 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat LPP PF04728.13 ORX77464.1 - 3.1 8.3 4.7 17 5.9 0.3 3.2 3 0 0 3 3 2 0 Lipoprotein leucine-zipper FAD_binding_3 PF01494.19 ORX77466.1 - 6.2e-08 32.3 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ORX77466.1 - 0.0028 16.8 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Peptidase_S28 PF05577.12 ORX77466.1 - 0.064 12.0 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Carn_acyltransf PF00755.20 ORX77487.1 - 1.2e-193 645.0 0.0 1.3e-193 644.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase REV1_C PF16727.5 ORX77488.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Myb_DNA-bind_4 PF13837.6 ORX77489.1 - 5.9e-13 49.0 1.2 2.3e-05 24.7 0.2 2.7 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain DUF743 PF05332.11 ORX77489.1 - 0.062 13.4 0.4 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) SAM_PNT PF02198.16 ORX77489.1 - 0.13 12.2 0.1 7.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Acetyltransf_2 PF00797.17 ORX77490.1 - 2.2e-43 148.8 0.0 2.5e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core2 PF13369.6 ORX77490.1 - 0.14 11.7 0.1 0.61 9.6 0.0 1.9 2 1 0 2 2 2 0 Transglutaminase-like superfamily Aconitase PF00330.20 ORX77512.1 - 1.1e-164 548.8 0.0 1.3e-164 548.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX77512.1 - 9.2e-41 139.2 0.0 1.9e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_1_2 PF00155.21 ORX77513.1 - 5.3e-89 298.9 0.0 6e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acyl-CoA_dh_1 PF00441.24 ORX77514.1 - 2.7e-41 141.3 0.3 3.8e-41 140.8 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX77514.1 - 4e-22 78.2 0.1 8.2e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORX77514.1 - 2.5e-21 75.6 0.0 6.5e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORX77514.1 - 1.4e-19 70.8 0.0 3.2e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX77514.1 - 2.8e-07 30.9 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Usp PF00582.26 ORX77515.1 - 9.5e-25 87.7 0.0 2.3e-24 86.5 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein family Ribosomal_L38e PF01781.18 ORX77516.1 - 1.5e-35 121.1 1.7 1.7e-35 121.0 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORX77516.1 - 0.065 13.5 0.0 0.072 13.3 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORX77516.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 zf-LYAR PF08790.11 ORX77517.1 - 3e-14 52.6 5.8 3e-14 52.6 5.8 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 ORX77517.1 - 0.047 13.3 1.2 0.28 10.8 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DM PF00751.18 ORX77517.1 - 0.22 11.4 4.5 0.49 10.4 4.5 1.6 1 0 0 1 1 1 0 DM DNA binding domain Presenilin PF01080.17 ORX77517.1 - 1.6 7.4 5.7 2 7.1 5.7 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_M24 PF00557.24 ORX77518.1 - 6.3e-51 173.0 0.1 7.7e-51 172.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORX77518.1 - 4.8e-21 74.8 9.7 1.1e-20 73.6 9.7 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORX77518.1 - 9.7e-06 25.6 5.4 2.8e-05 24.1 5.4 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORX77518.1 - 0.003 17.4 5.0 0.006 16.4 5.0 1.5 1 0 0 1 1 1 1 HIT zinc finger NUFIP1 PF10453.9 ORX77518.1 - 0.19 11.6 0.8 0.71 9.8 0.2 2.1 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Aa_trans PF01490.18 ORX77519.1 - 5.2e-60 203.3 33.8 6.1e-60 203.0 33.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 ORX77520.1 - 6.5e-61 206.3 36.3 7.9e-61 206.0 36.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L22 PF00237.19 ORX77521.1 - 6.5e-43 145.2 0.1 8.7e-43 144.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Sel1 PF08238.12 ORX77522.1 - 2e-17 63.2 27.5 0.0024 18.5 0.1 9.5 9 1 0 9 9 9 7 Sel1 repeat TPR_11 PF13414.6 ORX77522.1 - 8.9 6.1 12.3 15 5.3 0.1 5.4 5 0 0 5 5 5 0 TPR repeat MFS_1 PF07690.16 ORX77541.1 - 1.2e-26 93.6 48.1 2.9e-26 92.2 47.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX77541.1 - 0.00017 20.6 31.0 0.0016 17.4 10.1 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter Kinesin PF00225.23 ORX77542.1 - 3.5e-99 331.9 3.5 4.8e-99 331.4 3.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX77542.1 - 1.9e-20 73.3 0.2 1.1e-17 64.3 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding Syntaxin-18_N PF10496.9 ORX77542.1 - 0.09 13.0 4.5 6.8 7.0 0.1 4.1 2 2 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Xan_ur_permease PF00860.20 ORX77543.1 - 9.1e-64 215.5 34.9 2.8e-62 210.6 34.9 2.2 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 ORX77543.1 - 1.5 9.2 18.3 0.9 10.0 6.1 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 ORX77544.1 - 9.1e-64 215.6 34.9 2.8e-62 210.6 34.9 2.2 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 ORX77544.1 - 1.5 9.2 18.3 0.9 10.0 6.1 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 ORX77545.1 - 5.6e-09 35.2 0.3 5.6e-09 35.2 0.3 1.7 2 0 0 2 2 2 1 Permease family Pox_A_type_inc PF04508.12 ORX77545.1 - 0.36 10.7 1.4 0.6 10.1 1.4 1.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MMM1 PF10296.9 ORX77546.1 - 1.2e-65 221.8 0.5 1.5e-62 211.6 0.5 3.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF2798 PF11391.8 ORX77546.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) CorA PF01544.18 ORX77571.1 - 2.9e-55 187.6 0.9 3.5e-55 187.4 0.9 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SET PF00856.28 ORX77572.1 - 1.1e-08 35.6 0.0 2.1e-06 28.2 0.0 2.2 1 1 1 2 2 2 2 SET domain SAF PF08666.12 ORX77572.1 - 0.048 14.3 0.0 4.5 8.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain SCAMP PF04144.13 ORX77573.1 - 9e-46 156.3 11.8 1e-45 156.1 11.8 1.0 1 0 0 1 1 1 1 SCAMP family zf-BED PF02892.15 ORX77574.1 - 2.8e-06 27.3 0.8 4.7e-06 26.5 0.8 1.4 1 0 0 1 1 1 1 BED zinc finger TALPID3 PF15324.6 ORX77574.1 - 0.021 12.5 6.5 0.025 12.3 6.5 1.0 1 0 0 1 1 1 0 Hedgehog signalling target SCIMP PF15050.6 ORX77574.1 - 0.28 11.7 2.5 0.52 10.8 2.5 1.4 1 0 0 1 1 1 0 SCIMP protein Nucleo_P87 PF07267.11 ORX77574.1 - 0.91 8.3 7.5 1.2 8.0 7.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AA_permease_2 PF13520.6 ORX77575.1 - 1.1e-61 209.0 32.0 1.8e-61 208.3 31.8 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX77575.1 - 2.3e-45 155.1 35.8 2.3e-45 155.1 35.8 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX77575.1 - 4.3e-09 36.3 4.1 6.9e-09 35.7 1.4 2.8 2 0 0 2 2 2 1 C-terminus of AA_permease Acp26Ab PF05777.12 ORX77575.1 - 0.16 12.6 0.0 1 10.1 0.0 2.1 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) DUF3810 PF12725.7 ORX77576.1 - 0.018 14.4 1.8 0.022 14.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) BPD_transp_2 PF02653.16 ORX77576.1 - 0.035 13.3 0.3 0.035 13.3 0.3 1.8 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component MpPF26 PF07666.11 ORX77576.1 - 0.062 13.4 4.1 0.089 12.9 4.1 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 Meckelin PF09773.9 ORX77576.1 - 0.14 10.2 1.6 0.18 9.9 1.6 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) FtsL PF04999.13 ORX77576.1 - 0.34 11.0 3.3 6.1 6.9 0.4 2.1 1 1 1 2 2 2 0 Cell division protein FtsL DUF4525 PF15027.6 ORX77576.1 - 0.43 10.3 1.3 5 6.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Myb_DNA-binding PF00249.31 ORX77577.1 - 7.9e-50 166.8 9.8 7.2e-15 54.9 0.1 4.1 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX77577.1 - 1.2e-49 166.4 7.2 3.1e-15 56.2 0.1 4.2 1 1 3 4 4 4 4 Myb-like DNA-binding domain SLIDE PF09111.10 ORX77577.1 - 2.8e-14 53.1 0.5 0.0004 20.4 0.1 3.9 1 1 3 4 4 4 3 SLIDE Myb_DNA-bind_7 PF15963.5 ORX77577.1 - 3e-09 36.7 4.8 0.049 13.5 0.0 3.7 3 1 1 4 4 4 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORX77577.1 - 3.4e-07 30.4 3.9 0.022 14.9 0.0 4.1 2 2 2 4 4 4 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 ORX77577.1 - 1e-05 25.5 10.2 0.65 10.1 0.2 4.1 1 1 3 4 4 4 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 ORX77577.1 - 0.00068 19.8 0.7 6.6 7.0 0.0 4.1 4 1 0 4 4 4 2 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 ORX77577.1 - 0.013 15.6 4.0 8.9 6.5 0.0 4.7 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain Arg_decarbox_C PF17944.1 ORX77577.1 - 0.026 15.1 0.0 26 5.5 0.0 3.4 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension CBM65_1 PF18259.1 ORX77577.1 - 0.075 13.2 0.2 7.1 6.8 0.1 2.6 1 1 1 2 2 2 0 Carbohydrate binding module 65 domain 1 Tox-GHH PF15636.6 ORX77577.1 - 0.94 9.5 9.6 10 6.2 0.3 4.1 3 1 1 4 4 4 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin RRM_1 PF00076.22 ORX77578.1 - 1.1e-19 70.0 0.0 1.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ORX77578.1 - 0.00025 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_occluded PF16842.5 ORX77578.1 - 0.0059 16.4 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX77578.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 ORX77578.1 - 0.096 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRIM-19 PF06212.12 ORX77579.1 - 3.3e-35 120.9 0.1 3.9e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF3879 PF12995.7 ORX77579.1 - 0.093 12.4 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) DNA_pol_E_B PF04042.16 ORX77580.1 - 7.1e-47 159.5 0.1 1.1e-46 158.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORX77580.1 - 8.8e-42 142.3 0.0 1.4e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CHCH PF06747.13 ORX77581.1 - 3.7e-05 23.7 3.9 6.4e-05 23.0 3.9 1.4 1 0 0 1 1 1 1 CHCH domain zf-RanBP PF00641.18 ORX77581.1 - 0.00085 18.6 3.6 0.52 9.7 0.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others MTCP1 PF08991.10 ORX77581.1 - 0.0059 16.8 8.3 0.0069 16.6 8.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type ICL PF00463.21 ORX77582.1 - 6.6e-246 816.9 0.1 7.6e-246 816.7 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORX77582.1 - 1e-10 41.5 0.1 3.6e-10 39.7 0.0 1.8 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 ORX77582.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain NTF2 PF02136.20 ORX77583.1 - 2.6e-33 115.2 0.1 2.9e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 ORX77583.1 - 0.028 14.3 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Cyclin PF08613.11 ORX77584.1 - 1e-11 45.5 0.0 1.6e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX77584.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain ER_lumen_recept PF00810.18 ORX77584.1 - 0.037 14.9 0.1 0.062 14.1 0.1 1.3 1 1 0 1 1 1 0 ER lumen protein retaining receptor MAP65_ASE1 PF03999.12 ORX77606.1 - 9e-27 94.0 36.1 1.6e-26 93.2 36.1 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) TC1 PF15063.6 ORX77606.1 - 0.059 13.2 0.6 0.55 10.1 0.2 2.6 2 0 0 2 2 2 0 Thyroid cancer protein 1 RRM_1 PF00076.22 ORX77608.1 - 1.7e-12 46.9 0.0 2.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX77608.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HC2 PF07382.11 ORX77609.1 - 6.3e-10 39.4 48.6 6.3e-10 39.4 48.6 2.5 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 Cyclin_N PF00134.23 ORX77610.1 - 1.6e-13 50.5 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX77610.1 - 3.4e-10 40.5 0.0 4.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin Pmp3 PF01679.17 ORX77610.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Proteolipid membrane potential modulator DUF3020 PF11223.8 ORX77612.1 - 1e-21 77.2 9.0 1e-21 77.2 9.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) GRP PF07172.11 ORX77626.1 - 8.9 7.1 27.3 6.9 7.4 26.1 1.5 1 1 0 1 1 1 0 Glycine rich protein family GRP PF07172.11 ORX77628.1 - 4.3 8.1 24.8 9.3 7.0 24.8 1.8 1 1 0 1 1 1 0 Glycine rich protein family Peptidase_C9 PF01707.16 ORX77629.1 - 0.17 11.4 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C9 Aminotran_1_2 PF00155.21 ORX77647.1 - 7.2e-38 130.7 0.0 9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX77647.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ribosomal_S27e PF01667.17 ORX77648.1 - 3e-23 81.3 2.8 3.8e-23 80.9 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Cyclin PF08613.11 ORX77649.1 - 0.0026 18.2 0.2 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX77649.1 - 0.004 16.9 0.3 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3687 PF12459.8 ORX77649.1 - 0.054 13.0 0.5 0.14 11.7 0.3 1.8 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Mpv17_PMP22 PF04117.12 ORX77650.1 - 1.1e-24 86.4 0.2 1.9e-24 85.7 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Homeodomain PF00046.29 ORX77651.1 - 1.1e-16 60.4 1.9 1.2e-16 60.3 1.9 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX77651.1 - 0.0047 16.8 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain DSPc PF00782.20 ORX77679.1 - 6.6e-27 93.9 0.0 8.4e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TOM20_plant PF06552.12 ORX77679.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Endotoxin_C PF03944.14 ORX77679.1 - 0.13 12.6 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 delta endotoxin Polysacc_deac_1 PF01522.21 ORX77680.1 - 3.3e-30 104.5 0.0 4.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ferrochelatase PF00762.19 ORX77680.1 - 0.048 12.7 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrochelatase Cytochrom_C PF00034.21 ORX77681.1 - 7.5e-12 46.2 0.1 1.1e-11 45.7 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORX77681.1 - 3.6e-08 33.6 2.1 1.4e-07 31.7 2.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORX77681.1 - 0.002 17.8 1.8 0.016 14.9 1.7 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 ORX77681.1 - 0.017 15.8 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 ORX77681.1 - 0.058 13.0 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Ras PF00071.22 ORX77682.1 - 8.4e-60 201.0 0.2 9.7e-60 200.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX77682.1 - 9.4e-20 71.0 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX77682.1 - 1.7e-09 37.4 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX77682.1 - 2.3e-05 24.4 0.0 0.036 14.0 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORX77682.1 - 6.2e-05 22.6 0.1 0.00015 21.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ORX77682.1 - 0.00039 20.4 0.1 0.00085 19.3 0.1 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORX77682.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX77682.1 - 0.0059 16.2 0.1 0.015 14.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B CENP-M PF11111.8 ORX77682.1 - 0.17 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) CbiA PF01656.23 ORX77682.1 - 0.24 11.4 1.2 2.5 8.2 1.2 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ORX77682.1 - 0.46 10.2 2.8 2.3 8.0 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Iron_permease PF04120.12 ORX77705.1 - 6.4e-40 135.9 18.5 9.4e-17 61.0 0.5 4.1 4 0 0 4 4 4 4 Low affinity iron permease zf-C2H2 PF00096.26 ORX77706.1 - 3.5e-11 42.9 17.4 2.5e-06 27.7 1.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX77706.1 - 3.2e-09 36.8 14.5 1.7e-08 34.5 0.8 3.4 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX77706.1 - 4.6e-08 33.2 13.7 0.00048 20.7 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX77706.1 - 9.7e-06 25.7 5.2 0.017 15.4 0.5 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX77706.1 - 0.00027 21.2 3.8 0.00077 19.7 3.9 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORX77706.1 - 0.0008 19.3 3.1 0.054 13.5 0.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORX77706.1 - 0.0025 18.1 1.7 1.1 9.6 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 ORX77706.1 - 0.0067 16.3 6.8 0.93 9.5 3.5 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.7 ORX77706.1 - 0.0069 16.8 3.3 0.0077 16.6 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.9 ORX77706.1 - 0.045 13.5 0.2 4.2 7.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 ORX77706.1 - 0.083 12.7 0.2 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF3449 PF11931.8 ORX77706.1 - 0.093 12.5 0.8 0.096 12.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) GAGA PF09237.11 ORX77706.1 - 0.12 12.2 6.9 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 GAGA factor UBZ_FAAP20 PF15750.5 ORX77706.1 - 0.15 12.0 0.3 21 5.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DUF629 PF04780.12 ORX77706.1 - 0.17 10.4 1.2 0.17 10.4 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf_ZIC PF18366.1 ORX77706.1 - 0.19 11.9 3.2 1.4 9.1 0.5 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain Zf_RING PF16744.5 ORX77706.1 - 0.19 11.9 1.2 0.17 12.1 0.3 1.5 1 1 1 2 2 2 0 KIAA1045 RING finger zf-met2 PF12907.7 ORX77706.1 - 0.21 11.8 0.2 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 Zinc-binding zf-MYST PF17772.1 ORX77706.1 - 0.36 10.5 5.8 2.6 7.7 0.5 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain DUF2256 PF10013.9 ORX77706.1 - 0.4 10.8 2.7 1.8 8.7 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH PF01844.23 ORX77706.1 - 0.59 10.4 5.8 2 8.6 0.9 2.1 2 0 0 2 2 2 0 HNH endonuclease zf-MYND PF01753.18 ORX77706.1 - 2.6 8.2 7.5 33 4.7 7.5 2.1 1 1 0 1 1 1 0 MYND finger Cyclin PF08613.11 ORX77708.1 - 7.9e-11 42.6 0.0 8.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX77708.1 - 8.2e-11 41.7 0.0 1.7e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Phenol_monoox PF04663.12 ORX77708.1 - 0.027 14.6 0.3 0.059 13.5 0.3 1.6 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Pox_A9 PF04835.12 ORX77750.1 - 0.0043 17.2 0.1 0.0066 16.6 0.1 1.2 1 0 0 1 1 1 1 A9 protein conserved region AA_permease_2 PF13520.6 ORX77750.1 - 0.12 11.2 0.1 0.22 10.3 0.0 1.4 2 0 0 2 2 2 0 Amino acid permease FUSC_2 PF13515.6 ORX77751.1 - 2.1e-17 63.4 15.1 4.4e-17 62.4 15.1 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ALMT PF11744.8 ORX77751.1 - 3.4e-13 49.3 6.9 5.1e-13 48.7 6.9 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter ArAE_2 PF10334.9 ORX77751.1 - 2.5e-12 47.2 1.5 7.1e-12 45.7 1.1 1.9 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ORX77751.1 - 3.2e-08 32.6 20.0 3.3e-07 29.3 20.0 2.3 1 1 0 1 1 1 1 Fusaric acid resistance protein family Glyco_hydro_18 PF00704.28 ORX77753.1 - 3.6e-26 92.6 0.0 4.6e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3421 PF11901.8 ORX77782.1 - 1.9e-60 201.9 14.9 2.8e-18 66.0 0.2 4.3 1 1 3 4 4 4 4 Protein of unknown function (DUF3421) HTH_7 PF02796.15 ORX77782.1 - 2.1 8.5 5.4 28 4.9 0.1 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase ProRS-C_1 PF09180.11 ORX77783.1 - 4.8e-25 87.6 1.0 9.8e-25 86.6 1.0 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 ORX77783.1 - 1.2e-16 61.2 0.0 2.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORX77783.1 - 8.7e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 ORX77783.1 - 4e-12 46.3 0.1 7.2e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Peptidase_M29 PF02073.15 ORX77784.1 - 0.00077 18.4 1.6 0.15 10.8 0.0 2.0 2 0 0 2 2 2 2 Thermophilic metalloprotease (M29) Arylesterase PF01731.20 ORX77785.1 - 9.9e-15 54.5 0.2 1.7e-13 50.5 0.1 2.3 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 ORX77785.1 - 0.00067 19.7 0.0 0.018 15.2 0.0 2.8 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 ORX77785.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region TMA7 PF09072.10 ORX77786.1 - 2.4e-29 102.0 23.2 2.6e-29 101.8 23.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 ORX77787.1 - 7.3e-71 238.6 0.0 8.8e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX77787.1 - 1.7e-35 122.5 0.0 2.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX77787.1 - 4.3e-05 23.0 0.0 0.00059 19.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX77787.1 - 0.0053 15.8 0.1 0.016 14.2 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORX77787.1 - 0.091 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 ORX77788.1 - 2.4e-54 181.3 1.6 8.6e-21 73.7 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA_synthFbeta PF17759.1 ORX77789.1 - 3.6e-48 163.8 0.0 5.1e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 ORX77789.1 - 9.8e-30 102.6 0.7 2e-28 98.4 0.2 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 ORX77789.1 - 2.1e-29 102.5 0.1 5.6e-29 101.0 0.1 1.8 1 1 0 1 1 1 1 B3/4 domain B5 PF03484.15 ORX77789.1 - 7.5e-22 77.4 0.1 2.7e-18 66.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 ORX77789.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DNA_pol3_a_NII PF11490.8 ORX77789.1 - 0.26 11.2 0.9 0.84 9.5 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TRAM_LAG1_CLN8 PF03798.16 ORX77807.1 - 1e-42 146.1 34.7 2.8e-42 144.7 30.4 2.2 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 ORX77807.1 - 5.5e-21 74.0 0.1 5.5e-21 74.0 0.1 2.8 3 0 0 3 3 3 1 TRAM1-like protein Peptidase_S8 PF00082.22 ORX77808.1 - 5.8e-35 121.0 15.7 1.5e-34 119.6 15.7 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX77808.1 - 0.00065 20.3 0.5 0.0012 19.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 LSM PF01423.22 ORX77809.1 - 4.4e-22 77.5 0.0 4.9e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX77809.1 - 1.3e-05 25.3 0.0 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Aminotran_5 PF00266.19 ORX77834.1 - 3.7e-16 59.0 0.0 5.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MarR_2 PF12802.7 ORX77835.1 - 1.6e-14 53.6 0.0 50 3.9 0.0 10.0 10 0 0 10 10 10 0 MarR family YqfQ PF14181.6 ORX77835.1 - 2.5e-13 50.6 4.5 7.6 6.7 0.0 9.4 10 0 0 10 10 10 1 YqfQ-like protein SUFU PF05076.13 ORX77835.1 - 1.4e-12 47.9 0.0 63 3.5 0.0 9.9 10 0 0 10 10 10 0 Suppressor of fused protein (SUFU) Arc_C PF18162.1 ORX77835.1 - 3.5e-10 39.6 12.9 41 4.1 0.0 11.1 11 0 0 11 11 11 0 Arc C-lobe ChpXY PF10216.9 ORX77835.1 - 3.3e-08 33.1 0.0 29 3.7 0.0 8.5 7 3 1 8 8 8 0 CO2 hydration protein (ChpXY) DUF348 PF03990.14 ORX77835.1 - 3.3e-07 30.0 30.2 31 4.4 0.1 10.3 10 0 0 10 10 10 0 G5-linked-Ubiquitin-like domain PHB_acc PF05233.13 ORX77835.1 - 3.5e-07 30.1 0.0 59 3.8 0.0 7.8 7 0 0 7 7 7 0 PHB accumulation regulatory domain MarR PF01047.22 ORX77835.1 - 6.8e-06 25.9 0.0 4.6e+02 0.8 0.0 8.8 10 0 0 10 10 10 0 MarR family Feld-I_B PF09252.10 ORX77835.1 - 0.0019 18.1 12.4 36 4.4 0.0 8.0 9 0 0 9 9 9 0 Allergen Fel d I-B chain DUF4926 PF16277.5 ORX77835.1 - 0.0023 17.3 36.8 22 4.5 0.3 10.5 11 0 0 11 11 11 0 Domain of unknown function (DUF4926) Msg2_C PF12373.8 ORX77835.1 - 0.33 10.4 28.8 15 5.1 0.1 9.7 10 0 0 10 10 10 0 Major surface glycoprotein 2 C terminal adh_short PF00106.25 ORX77836.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Synaptobrevin PF00957.21 ORX77838.1 - 1.1e-30 105.2 4.5 1.2e-30 105.1 4.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Baculo_F PF12259.8 ORX77838.1 - 0.0043 15.7 0.3 0.0049 15.5 0.3 1.1 1 0 0 1 1 1 1 Baculovirus F protein MCU PF04678.13 ORX77838.1 - 0.031 14.4 0.1 0.035 14.2 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 ORX77838.1 - 0.058 12.9 0.5 0.058 12.9 0.5 1.5 1 1 1 2 2 2 0 fzo-like conserved region KdpA PF03814.15 ORX77838.1 - 0.075 11.2 0.0 0.083 11.1 0.0 1.0 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit Herpes_teg_N PF04843.12 ORX77838.1 - 0.095 12.4 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region FeoB_associated PF12669.7 ORX77838.1 - 0.23 11.9 1.0 0.33 11.4 1.0 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein E1-E2_ATPase PF00122.20 ORX77839.1 - 2.5e-12 46.7 0.0 3.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Kp4 PF09044.10 ORX77841.1 - 5.1e-24 84.7 0.9 5.8e-24 84.6 0.9 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORX77841.1 - 0.0088 16.8 0.7 0.017 15.9 0.7 1.6 1 1 0 1 1 1 1 Meiotically up-regulated gene family Band_7 PF01145.25 ORX77842.1 - 2.6e-29 102.5 2.0 3.6e-29 102.0 2.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX77842.1 - 0.029 14.1 0.1 0.053 13.2 0.1 1.4 1 1 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORX77842.1 - 0.053 13.1 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 P5CR_dimer PF14748.6 ORX77865.1 - 1.8e-35 121.3 2.1 3.3e-35 120.5 2.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORX77865.1 - 7.1e-15 55.4 0.1 1.9e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AIRS PF00586.24 ORX77865.1 - 0.064 13.9 2.2 0.076 13.7 0.3 2.1 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Pacifastin_I PF05375.13 ORX77866.1 - 2.3e-05 24.0 6.1 3.1e-05 23.6 6.1 1.3 1 1 0 1 1 1 1 Pacifastin inhibitor (LCMII) FAINT PF04385.15 ORX77866.1 - 0.072 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, DUF529 4HBT_3 PF13622.6 ORX77867.1 - 3.9e-58 197.6 0.0 4.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORX77867.1 - 1.5e-37 128.4 0.0 9.6e-30 103.1 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 2-oxogl_dehyd_N PF16078.5 ORX77867.1 - 0.11 12.1 0.6 0.25 11.0 0.3 1.8 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus STT3 PF02516.14 ORX77867.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit zf-C2H2 PF00096.26 ORX77868.1 - 1.6e-21 75.5 31.9 3.7e-06 27.1 1.8 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX77868.1 - 2e-19 69.0 31.8 1.6e-09 37.8 1.0 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX77868.1 - 4.8e-14 51.9 29.5 0.00067 20.3 2.0 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX77868.1 - 1.1e-06 29.1 10.0 0.07 13.8 0.3 3.2 2 1 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX77868.1 - 0.00028 21.1 9.8 0.019 15.2 1.8 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX77868.1 - 0.00099 19.8 11.3 0.013 16.2 2.8 3.0 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2H2_6 PF13912.6 ORX77868.1 - 0.0015 18.5 23.6 0.03 14.3 0.4 4.5 4 1 0 4 4 4 2 C2H2-type zinc finger DUF3268 PF11672.8 ORX77868.1 - 0.0017 18.7 2.5 0.2 12.0 0.5 2.1 2 0 0 2 2 2 2 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 ORX77868.1 - 0.096 13.0 12.0 9.6 6.6 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 ORX77868.1 - 0.38 10.9 5.8 1.3 9.2 1.5 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_aberr PF17017.5 ORX77868.1 - 0.64 10.1 6.0 7.9 6.6 1.5 3.2 2 1 2 4 4 4 0 Aberrant zinc-finger C1_4 PF07975.12 ORX77868.1 - 0.93 9.8 6.8 0.69 10.2 2.9 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain RhoGAP PF00620.27 ORX77869.1 - 0.084 12.7 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 RhoGAP domain PH PF00169.29 ORX77870.1 - 9.2e-09 35.8 0.5 1.6e-08 35.0 0.5 1.3 1 0 0 1 1 1 1 PH domain PBD PF00786.28 ORX77870.1 - 9.1e-08 32.4 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH_9 PF15410.6 ORX77870.1 - 0.0094 16.3 0.2 0.31 11.4 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain ADH_zinc_N_2 PF13602.6 ORX77919.1 - 2.4e-17 64.3 0.0 3.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX77919.1 - 2.5e-14 53.4 0.0 3.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX77919.1 - 8.9e-09 35.2 0.0 2.3e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ALO PF04030.14 ORX77920.1 - 2.1e-22 80.2 0.2 1.9e-15 57.4 0.1 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ORX77920.1 - 3.9e-22 78.5 2.6 3.9e-22 78.5 2.6 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 ORX77944.1 - 1.8e-32 112.3 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORX77944.1 - 3.3e-23 81.9 0.0 5.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORX77944.1 - 3.2e-09 37.1 0.0 8.2e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORX77944.1 - 0.12 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PPR_2 PF13041.6 ORX77946.1 - 5.1e-55 183.5 8.4 1.5e-13 50.7 0.1 9.6 4 2 5 10 10 10 10 PPR repeat family PPR_1 PF12854.7 ORX77946.1 - 3.4e-39 132.2 0.1 5.4e-07 29.2 0.0 9.8 10 0 0 10 10 10 6 PPR repeat PPR PF01535.20 ORX77946.1 - 7e-37 123.1 9.7 1.7e-05 24.7 0.1 12.0 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.6 ORX77946.1 - 6.8e-34 115.8 7.8 9.2e-08 32.1 0.0 8.2 3 2 5 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX77946.1 - 1.9e-13 50.3 0.7 0.0041 16.5 0.0 4.6 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX77946.1 - 2.2e-10 41.0 3.3 0.00043 20.7 0.1 6.5 3 2 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 ORX77946.1 - 2.6e-05 24.7 0.1 5.4 7.6 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX77946.1 - 0.0014 17.6 7.2 0.53 9.1 0.7 5.1 2 1 3 5 5 5 2 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 ORX77946.1 - 0.0039 17.9 0.1 14 6.8 0.0 5.0 4 2 1 5 5 4 1 Tetratricopeptide repeat CNOT1_TTP_bind PF16417.5 ORX77946.1 - 0.0059 15.8 0.9 2.5 7.2 0.1 3.4 3 0 0 3 3 3 2 CCR4-NOT transcription complex subunit 1 TTP binding domain CCM2_C PF16545.5 ORX77946.1 - 0.09 13.3 0.4 23 5.6 0.0 3.9 4 1 1 5 5 5 0 Cerebral cavernous malformation protein, harmonin-homology DUF727 PF05303.12 ORX77947.1 - 1.3e-11 44.4 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) 60KD_IMP PF02096.20 ORX77948.1 - 6.1e-26 91.3 1.0 7.5e-26 91.0 1.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Sacchrp_dh_C PF16653.5 ORX77949.1 - 5.6e-29 102.0 0.0 7.8e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain COX1 PF00115.20 ORX77971.1 - 6.1e-07 28.6 0.3 6.6e-07 28.5 0.3 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 ORX77972.1 - 1.7e-80 271.0 38.6 2.3e-80 270.6 38.6 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I P2X_receptor PF00864.19 ORX77973.1 - 1.1e-18 67.5 0.7 2.6e-10 39.9 0.1 2.6 2 1 1 3 3 3 2 ATP P2X receptor Peptidase_M99_m PF17130.4 ORX77974.1 - 0.00018 21.3 0.1 29 4.7 0.0 4.3 4 0 0 4 4 4 1 beta-barrel domain of carboxypeptidase M99 DUF2593 PF10767.9 ORX77974.1 - 0.064 13.3 0.2 38 4.3 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2593) PorB PF11565.8 ORX77974.1 - 0.76 10.2 10.6 83 3.7 0.1 4.4 4 0 0 4 4 4 0 Alpha helical Porin B Peptidase_M99_m PF17130.4 ORX77975.1 - 0.00084 19.2 0.2 29 4.7 0.0 4.3 4 0 0 4 4 4 3 beta-barrel domain of carboxypeptidase M99 Aconitase PF00330.20 ORX77976.1 - 4.2e-153 510.7 0.0 5.3e-153 510.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX77976.1 - 1.6e-43 148.2 0.0 2.8e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain p450 PF00067.22 ORX77991.1 - 1e-79 268.5 0.1 1.3e-79 268.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3847 PF12958.7 ORX77992.1 - 0.028 14.5 1.5 7.9 6.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) ABC_tran_CTD PF16326.5 ORX77992.1 - 0.044 14.0 3.1 0.082 13.2 3.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain RRN9 PF10680.9 ORX77992.1 - 0.055 13.8 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor ABC_membrane PF00664.23 ORX77993.1 - 1.4e-99 333.2 28.0 3.8e-50 171.1 6.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX77993.1 - 1e-66 223.7 0.5 1.4e-33 116.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX77993.1 - 1.9e-18 66.7 5.2 5.1e-07 29.4 0.1 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORX77993.1 - 4.6e-08 32.3 3.8 0.00059 18.7 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORX77993.1 - 1.8e-06 27.6 2.6 0.018 14.8 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 ORX77993.1 - 2.7e-06 27.8 1.3 3 8.3 0.0 4.0 3 1 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX77993.1 - 3.6e-06 27.4 1.8 0.026 14.9 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORX77993.1 - 1.3e-05 25.2 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORX77993.1 - 1.8e-05 25.1 0.7 0.12 12.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 ORX77993.1 - 3.8e-05 23.4 0.1 1.3 8.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 ORX77993.1 - 6.9e-05 23.1 0.7 0.57 10.2 0.0 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_23 PF13476.6 ORX77993.1 - 0.00031 21.3 0.8 0.7 10.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 ORX77993.1 - 0.00047 20.0 0.0 0.47 10.1 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 ORX77993.1 - 0.00074 19.5 0.2 0.85 9.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 ORX77993.1 - 0.00078 18.8 0.5 0.13 11.5 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 ORX77993.1 - 0.00083 19.1 1.7 1.1 8.9 0.5 3.5 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORX77993.1 - 0.0014 18.5 0.7 4.5 7.0 0.0 3.9 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 ORX77993.1 - 0.003 17.5 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.6 ORX77993.1 - 0.0046 17.2 2.8 1.6 9.0 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ORX77993.1 - 0.0095 16.5 0.0 7.5 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORX77993.1 - 0.014 15.0 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 ORX77993.1 - 0.018 14.8 0.0 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORX77993.1 - 0.028 14.6 0.0 9.2 6.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORX77993.1 - 0.046 12.9 0.2 3.7 6.6 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 ORX77993.1 - 0.078 13.1 0.3 9.6 6.3 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORX77993.1 - 0.089 12.5 0.1 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX77993.1 - 0.11 12.9 0.0 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 ORX77993.1 - 0.15 12.5 0.0 28 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 ORX77993.1 - 0.24 10.6 1.4 9.6 5.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain K_oxygenase PF13434.6 ORX77994.1 - 6.8e-100 334.5 0.0 1e-99 333.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Acetyltransf_8 PF13523.6 ORX77994.1 - 1.3e-50 170.8 0.0 2.2e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 ORX77994.1 - 6.2e-05 22.4 0.0 0.0018 17.5 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_3 PF13302.7 ORX77994.1 - 0.00023 21.9 0.0 0.00053 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_9 PF13454.6 ORX77994.1 - 0.002 18.1 0.0 3.7 7.5 0.0 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORX77994.1 - 0.002 17.4 1.5 0.024 13.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DPBB_1 PF03330.18 ORX77995.1 - 3.5e-10 40.0 0.4 1.3e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Lytic transglycolase CBM_14 PF01607.24 ORX77995.1 - 0.1 12.8 4.0 0.98 9.6 1.5 2.8 2 1 0 2 2 2 0 Chitin binding Peritrophin-A domain DUF4028 PF13220.6 ORX77996.1 - 9.5 6.1 29.1 5.7 6.8 0.7 7.5 2 2 6 8 8 8 0 Protein of unknown function (DUF4028) SOP4 PF17081.5 ORX77998.1 - 9.6 5.7 15.6 2 7.9 0.8 5.1 2 2 4 7 7 7 0 Suppressor of PMA 1-7 protein NicO PF03824.16 ORX77999.1 - 1e-84 284.2 13.4 1e-84 284.2 13.4 1.6 2 0 0 2 2 2 1 High-affinity nickel-transport protein NicO PF03824.16 ORX78000.1 - 2.2e-53 181.5 3.7 2.5e-53 181.3 3.7 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein MHYT PF03707.16 ORX78000.1 - 0.15 12.3 0.3 0.15 12.3 0.3 2.5 2 1 1 3 3 3 0 Bacterial signalling protein N terminal repeat Methyltransf_25 PF13649.6 ORX78001.1 - 3.7e-13 50.0 0.0 1.4e-12 48.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX78001.1 - 3.8e-12 46.7 0.0 1.1e-11 45.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX78001.1 - 2.7e-11 43.6 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX78001.1 - 7.5e-11 42.0 0.0 1.9e-09 37.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX78001.1 - 0.00036 19.9 0.0 0.0021 17.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORX78001.1 - 0.0023 18.7 0.0 0.0089 16.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORX78001.1 - 0.0031 16.8 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORX78001.1 - 0.013 15.0 0.0 0.13 11.7 0.0 2.4 2 1 0 3 3 3 0 Putative methyltransferase FtsJ PF01728.19 ORX78001.1 - 0.016 15.4 0.0 0.046 13.8 0.0 1.7 2 1 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 ORX78001.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Myticin-prepro PF10690.9 ORX78022.1 - 0.0038 17.4 0.2 0.0058 16.8 0.2 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Lipase_3 PF01764.25 ORX78025.1 - 1.9e-20 73.2 0.3 2.4e-20 72.8 0.3 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX78025.1 - 0.021 15.4 0.0 0.025 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 ORX78025.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 ORX78025.1 - 0.026 14.1 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 ORX78025.1 - 0.058 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 ORX78025.1 - 0.072 12.7 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 ORX78025.1 - 0.089 12.5 0.3 0.11 12.2 0.3 1.4 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 ORX78026.1 - 2e-19 69.9 0.2 1.2e-17 64.1 0.0 2.9 3 1 1 4 4 4 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORX78026.1 - 0.0046 16.2 0.2 0.095 11.9 0.1 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORX78026.1 - 0.028 14.0 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 ORX78026.1 - 0.052 13.1 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 ORX78026.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Myticin-prepro PF10690.9 ORX78056.1 - 0.0041 17.3 0.4 0.0062 16.8 0.4 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel adh_short PF00106.25 ORX78057.1 - 1.5e-30 106.1 0.0 7.5e-23 81.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX78057.1 - 1e-21 77.6 0.0 1.6e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX78057.1 - 1.4e-09 38.1 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX78057.1 - 0.0017 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORX78057.1 - 0.011 15.8 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORX78057.1 - 0.032 14.7 0.1 0.076 13.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding PA PF02225.22 ORX78057.1 - 0.046 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 PA domain Myticin-prepro PF10690.9 ORX78059.1 - 0.03 14.6 0.2 0.041 14.1 0.2 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF3575 PF12099.8 ORX78059.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) Fungal_trans PF04082.18 ORX78079.1 - 6.8e-35 120.4 0.0 1.4e-34 119.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain cwf21 PF08312.12 ORX78080.1 - 2e-16 59.8 7.7 2e-16 59.8 7.7 1.9 2 0 0 2 2 2 1 cwf21 domain DUF1492 PF07374.11 ORX78080.1 - 0.18 12.0 1.5 0.25 11.5 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) SOAR PF16533.5 ORX78080.1 - 2 8.4 8.8 0.34 10.9 2.3 2.4 1 1 2 3 3 3 0 STIM1 Orai1-activating region MutS_V PF00488.21 ORX78103.1 - 2.3e-24 86.5 1.2 2.5e-24 86.3 1.2 1.0 1 0 0 1 1 1 1 MutS domain V WH2 PF02205.20 ORX78104.1 - 9.7e-11 41.1 0.3 2.5e-10 39.8 0.3 1.8 1 0 0 1 1 1 1 WH2 motif Methyltransf_16 PF10294.9 ORX78105.1 - 4.4e-07 29.8 0.0 0.0074 16.0 0.0 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 ORX78105.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX78105.1 - 2.3e-05 24.2 0.3 0.0002 21.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX78105.1 - 0.00031 21.4 0.0 0.0024 18.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX78105.1 - 0.0024 18.5 0.0 0.52 11.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX78105.1 - 0.0088 16.7 0.0 0.26 12.0 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Baculo_p47 PF05112.12 ORX78105.1 - 0.035 13.7 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Baculovirus P47 protein MTS PF05175.14 ORX78105.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain UNC-93 PF05978.16 ORX78106.1 - 2.9e-11 43.3 4.7 1.1e-10 41.5 4.7 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX78106.1 - 7.6e-10 38.2 33.9 7.9e-10 38.2 30.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX78107.1 - 2.9e-11 43.3 4.7 1.1e-10 41.5 4.7 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX78107.1 - 7.6e-10 38.2 33.9 7.9e-10 38.2 30.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX78108.1 - 1.3e-10 41.2 4.6 2.1e-10 40.6 4.6 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX78108.1 - 3.7e-10 39.3 8.6 4.4e-10 39.0 8.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ERbeta_N PF12497.8 ORX78108.1 - 0.19 11.6 0.0 0.6 9.9 0.0 1.7 2 0 0 2 2 2 0 Estrogen receptor beta R3H PF01424.22 ORX78132.1 - 6.7e-18 64.4 0.2 1.4e-17 63.4 0.2 1.5 1 0 0 1 1 1 1 R3H domain JAKMIP_CC3 PF16034.5 ORX78132.1 - 0.069 13.1 0.1 8.6 6.2 0.0 2.5 3 0 0 3 3 3 0 JAKMIP CC3 domain Arrestin_N PF00339.29 ORX78133.1 - 4.3e-07 30.1 0.0 2.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX78133.1 - 7.7e-06 26.4 0.1 0.0038 17.7 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain C2 PF00168.30 ORX78135.1 - 2.6e-16 59.8 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 ORX78135.1 - 0.053 13.6 0.0 0.089 12.9 0.0 1.4 1 1 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 PBP PF01161.20 ORX78136.1 - 4.3e-18 65.9 0.1 5.5e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein UQ_con PF00179.26 ORX78137.1 - 6.5e-39 132.8 0.6 9.2e-39 132.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORX78137.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B GPI-anchored PF10342.9 ORX78138.1 - 0.0017 19.1 0.9 0.0022 18.7 0.9 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAR2 PF16974.5 ORX78138.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.4 1 1 0 1 1 1 1 High-affinity nitrate transporter accessory DUF4625 PF15418.6 ORX78138.1 - 0.0049 17.1 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) MG2 PF01835.19 ORX78138.1 - 0.028 14.9 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 MG2 domain GPI-anchored PF10342.9 ORX78139.1 - 0.0017 19.1 0.9 0.0022 18.7 0.9 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAR2 PF16974.5 ORX78139.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.4 1 1 0 1 1 1 1 High-affinity nitrate transporter accessory DUF4625 PF15418.6 ORX78139.1 - 0.0049 17.1 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) MG2 PF01835.19 ORX78139.1 - 0.028 14.9 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 MG2 domain FAA_hydrolase PF01557.18 ORX78140.1 - 8.3e-54 182.5 0.0 1.2e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ORX78140.1 - 7.4e-38 129.0 0.0 3.1e-37 127.0 0.0 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Dynamin_N PF00350.23 ORX78174.1 - 1.7e-35 122.6 0.0 1.9e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORX78174.1 - 0.0002 21.4 0.1 0.0023 18.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX78174.1 - 0.0023 18.3 0.0 0.0024 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORX78174.1 - 0.016 14.7 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 ORX78174.1 - 0.02 15.2 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX78174.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.6 ORX78174.1 - 0.067 12.9 0.1 0.087 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 ORX78174.1 - 0.13 11.8 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ARD PF03079.14 ORX78175.1 - 1.8e-50 171.2 0.1 2.1e-50 171.0 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ORX78175.1 - 6.2e-11 41.9 0.1 1.3e-10 40.8 0.1 1.6 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.19 ORX78175.1 - 8.5e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ORX78175.1 - 2.5e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 ORX78175.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.6 ORX78175.1 - 0.026 14.2 0.0 0.06 13.1 0.0 1.5 1 1 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.7 ORX78175.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin COX15-CtaA PF02628.15 ORX78176.1 - 1.6e-107 359.4 6.3 1.9e-107 359.1 6.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 ORX78176.1 - 0.02 15.0 0.9 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Fumarate reductase subunit C KilA-N PF04383.13 ORX78178.1 - 2.9e-05 23.9 0.1 0.00043 20.1 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain OTCace PF00185.24 ORX78179.1 - 1.7e-51 174.4 0.1 3.1e-51 173.5 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ORX78179.1 - 2.7e-46 157.3 0.1 4.1e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SecE PF00584.20 ORX78180.1 - 1.5e-16 60.0 0.0 1.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SAS-6_N PF16531.5 ORX78180.1 - 0.13 12.9 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal Arf PF00025.21 ORX78182.1 - 2.9e-47 160.3 0.1 3.5e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORX78182.1 - 1e-21 77.2 0.0 1.2e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX78182.1 - 1.3e-17 64.1 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORX78182.1 - 3e-11 43.1 0.0 3.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORX78182.1 - 6.9e-09 35.4 0.0 8.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORX78182.1 - 2.2e-08 34.2 0.0 4.4e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORX78182.1 - 3.5e-08 33.0 0.8 6.5e-05 22.3 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 ORX78182.1 - 0.00014 21.5 0.0 0.0036 16.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ACT PF01842.25 ORX78182.1 - 0.011 15.5 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain AAA_7 PF12775.7 ORX78182.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 ORX78182.1 - 0.018 15.3 0.1 0.42 10.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORX78182.1 - 0.023 14.7 0.2 0.89 9.6 0.2 2.4 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.12 ORX78182.1 - 0.043 13.7 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 ORX78182.1 - 0.06 13.7 0.0 7.3 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain VirE PF05272.11 ORX78182.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E FeoB_N PF02421.18 ORX78182.1 - 0.071 12.6 0.6 0.14 11.7 0.1 1.8 2 1 1 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.27 ORX78182.1 - 0.11 13.0 0.1 0.15 12.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 ORX78182.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 ORX78182.1 - 0.12 12.0 0.0 17 5.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RasGAP PF00616.19 ORX78226.1 - 2.3e-32 112.4 0.7 2.9e-22 79.4 0.5 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 ORX78226.1 - 2e-16 60.1 0.0 4.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 ORX78226.1 - 4.6e-07 30.3 0.8 2e-06 28.2 0.4 2.3 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 ORX78226.1 - 0.02 15.2 0.1 0.043 14.1 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 ORX78226.1 - 1.1 9.7 3.7 0.37 11.2 0.4 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Ribosomal_L32e PF01655.18 ORX78227.1 - 1.1e-53 180.3 3.0 1.1e-53 180.3 3.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 Pkinase PF00069.25 ORX78228.1 - 7.6e-49 166.4 0.0 9.1e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX78228.1 - 1.1e-28 100.3 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX78228.1 - 0.063 12.2 0.3 0.094 11.6 0.2 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Peptidase_S10 PF00450.22 ORX78230.1 - 5.4e-130 434.6 1.0 6.7e-130 434.2 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.13 ORX78230.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold GTP_EFTU PF00009.27 ORX78231.1 - 4.9e-46 156.7 0.1 7.9e-46 156.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX78231.1 - 3.5e-15 56.3 0.0 1.2e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX78231.1 - 1.4e-10 41.4 0.7 2.7e-09 37.3 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX78231.1 - 2.5e-05 24.3 0.0 0.01 15.9 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORX78231.1 - 0.00016 21.5 0.3 0.00058 19.7 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ribosomal_S3_C PF00189.20 ORX78232.1 - 1e-23 83.6 1.1 3.9e-23 81.8 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORX78232.1 - 1.3e-12 47.4 0.1 2.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORX78232.1 - 0.048 14.2 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 ORX78232.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus HEAT PF02985.22 ORX78233.1 - 7.2e-51 165.8 17.7 0.0012 18.9 0.0 14.1 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 ORX78233.1 - 7.1e-41 138.5 2.4 1.5e-11 44.5 0.0 7.2 3 2 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.7 ORX78233.1 - 4.4e-14 52.8 1.5 0.024 15.2 0.0 6.7 4 3 2 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORX78233.1 - 3.2e-12 46.8 7.9 0.00066 19.8 1.2 5.5 4 1 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORX78233.1 - 6.2e-10 39.2 7.3 0.00038 20.6 0.1 5.5 5 1 1 6 6 6 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORX78233.1 - 1.3e-09 37.2 1.4 4.5e-07 28.8 0.0 3.1 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 ORX78233.1 - 2.6e-09 37.4 15.3 0.028 14.9 0.2 8.9 6 3 3 10 10 10 3 HEAT-like repeat RIX1 PF08167.12 ORX78233.1 - 0.0012 18.6 4.7 0.023 14.4 0.2 3.6 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 ORX78233.1 - 0.0015 18.8 0.1 16 5.9 0.0 4.8 3 2 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 ORX78233.1 - 0.0027 17.3 0.9 1.1 8.8 0.3 4.2 2 2 2 4 4 4 1 CLASP N terminal Arm PF00514.23 ORX78233.1 - 0.057 13.5 11.0 40 4.5 0.0 8.0 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 ORX78233.1 - 0.17 11.6 0.1 9.4 5.9 0.0 2.5 2 0 0 2 2 2 0 DNA alkylation repair enzyme Ecm29 PF13001.7 ORX78233.1 - 0.32 9.6 8.5 5.5 5.6 0.4 4.6 4 1 0 4 4 4 0 Proteasome stabiliser Gp_dh_C PF02800.20 ORX78234.1 - 2.4e-71 238.5 0.0 3.5e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORX78234.1 - 1.8e-40 137.3 0.1 3.7e-40 136.4 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX78234.1 - 0.0084 16.2 0.0 0.054 13.6 0.0 2.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Enolase_C PF00113.22 ORX78235.1 - 5.5e-158 524.8 0.0 9.1e-158 524.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORX78235.1 - 5.5e-59 198.0 0.1 8.8e-59 197.4 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORX78235.1 - 7.2e-10 38.8 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORX78235.1 - 0.003 16.8 0.3 0.0066 15.6 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus EF-hand_7 PF13499.6 ORX78235.1 - 0.049 14.1 0.3 0.62 10.6 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair GTP_EFTU PF00009.27 ORX78236.1 - 4.9e-46 156.7 0.1 7.9e-46 156.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX78236.1 - 3.5e-15 56.3 0.0 1.2e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX78236.1 - 1.4e-10 41.4 0.7 2.7e-09 37.3 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX78236.1 - 2.5e-05 24.3 0.0 0.01 15.9 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORX78236.1 - 0.00016 21.5 0.3 0.00058 19.7 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ICL PF00463.21 ORX78237.1 - 2.2e-251 834.9 0.3 2.5e-251 834.7 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORX78237.1 - 7.8e-10 38.6 0.2 1.7e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 ORX78237.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain TetR_C_10 PF16295.5 ORX78237.1 - 0.13 12.5 0.0 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-bind_4 PF13837.6 ORX78263.1 - 9.2e-18 64.4 1.3 1.3e-17 64.0 1.3 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX78263.1 - 3.1e-07 30.5 0.6 5.6e-07 29.7 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX78263.1 - 4.1e-06 26.9 0.7 8.2e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX78263.1 - 0.00011 22.5 0.6 0.00016 21.9 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORX78263.1 - 0.0045 18.0 0.9 0.0077 17.2 0.9 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CAS_C PF12026.8 ORX78264.1 - 1.2 9.2 6.2 0.57 10.2 0.8 2.1 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain Coilin_N PF15862.5 ORX78264.1 - 9.3 6.0 12.0 0.23 11.3 3.5 2.1 2 0 0 2 2 2 0 Coilin N-terminus Ribosomal_S11 PF00411.19 ORX78265.1 - 1.2e-47 160.8 1.3 1.5e-47 160.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Kinesin PF00225.23 ORX78266.1 - 5.2e-08 32.2 0.0 6.5e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain CLZ PF16526.5 ORX78266.1 - 0.015 15.7 3.9 0.015 15.7 3.9 4.7 3 2 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LPP PF04728.13 ORX78266.1 - 1.2 9.6 7.7 50 4.4 0.0 4.0 3 1 0 3 3 3 0 Lipoprotein leucine-zipper ORF6C PF10552.9 ORX78266.1 - 7.7 6.6 11.5 7.9 6.6 3.0 2.8 2 0 0 2 2 2 0 ORF6C domain Aminotran_1_2 PF00155.21 ORX78267.1 - 6.6e-74 249.3 0.0 7.6e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORX78267.1 - 1.5e-06 27.4 0.1 7.3e-06 25.2 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORX78267.1 - 0.00032 19.3 0.0 0.00052 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 ORX78267.1 - 0.0093 14.6 0.1 0.027 13.1 0.1 1.7 1 1 0 1 1 1 1 Serine hydroxymethyltransferase HTH_WhiA PF02650.14 ORX78267.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DegT_DnrJ_EryC1 PF01041.17 ORX78267.1 - 0.018 14.4 0.1 0.057 12.7 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORX78267.1 - 0.03 13.6 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase zf-C2H2 PF00096.26 ORX78268.1 - 3.2e-12 46.2 14.6 7.1e-06 26.2 4.1 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX78268.1 - 1.4e-10 41.1 12.3 5.3e-05 23.7 2.0 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX78268.1 - 8.7e-09 35.4 0.3 8.7e-09 35.4 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORX78268.1 - 1.6e-06 27.8 9.6 7.1e-05 22.5 2.9 2.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORX78268.1 - 6e-06 26.4 1.3 0.0073 16.6 0.4 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORX78268.1 - 7e-05 23.2 3.6 0.0088 16.5 0.3 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 ORX78268.1 - 0.00017 21.5 5.3 0.00047 20.1 1.0 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 ORX78268.1 - 0.00026 21.0 3.8 0.01 15.8 2.5 2.1 1 1 1 2 2 2 1 BED zinc finger zf-C2H2_2 PF12756.7 ORX78268.1 - 0.00039 20.7 1.6 0.5 10.7 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 ORX78268.1 - 0.0026 17.5 1.5 0.0026 17.5 1.5 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-FCS PF06467.14 ORX78268.1 - 0.0034 17.3 0.9 0.1 12.6 1.2 2.0 1 1 1 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf_C2H2_ZHX PF18387.1 ORX78268.1 - 0.0041 16.7 1.1 0.25 11.0 0.2 2.0 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain TRAF6_Z2 PF18048.1 ORX78268.1 - 0.039 14.1 2.7 0.31 11.2 0.7 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-LYAR PF08790.11 ORX78268.1 - 0.075 13.0 2.9 0.95 9.4 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 ORX78268.1 - 0.077 13.1 3.0 0.5 10.5 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 ORX78268.1 - 0.084 13.2 3.6 0.085 13.2 3.6 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon Actin_micro PF17003.5 ORX78268.1 - 0.15 11.3 0.5 0.23 10.6 0.3 1.5 1 1 1 2 2 2 0 Putative actin-like family Pox_A9 PF04835.12 ORX78268.1 - 0.22 11.7 0.1 0.29 11.3 0.1 1.2 1 0 0 1 1 1 0 A9 protein conserved region zf-MYST PF17772.1 ORX78268.1 - 0.3 10.7 1.8 4.6 6.9 0.2 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain zf-AN1 PF01428.16 ORX78268.1 - 0.62 10.3 6.2 6.6 7.0 1.7 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger AMP-binding PF00501.28 ORX78269.1 - 4.9e-96 321.9 0.0 6.3e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX78269.1 - 0.0002 22.3 0.0 0.00044 21.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain rRNA_proc-arch PF13234.6 ORX78294.1 - 7.2e-83 278.6 0.0 1.3e-82 277.7 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 ORX78294.1 - 1e-54 184.6 0.6 1e-54 184.6 0.6 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 ORX78294.1 - 1.2e-17 64.2 0.0 4.3e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX78294.1 - 1.1e-07 32.2 0.1 1.6e-06 28.4 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX78294.1 - 0.00037 20.5 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORX78294.1 - 0.048 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX78294.1 - 0.13 12.7 0.1 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain zf-C3HC4_3 PF13920.6 ORX78295.1 - 2.2e-05 24.2 9.6 3.5e-05 23.6 9.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX78295.1 - 0.16 11.8 14.3 0.26 11.2 14.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX78295.1 - 0.99 9.3 12.8 1.9 8.4 12.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GPI-anchored PF10342.9 ORX78318.1 - 1.4e-05 25.7 0.3 0.0001 23.0 0.3 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3291 PF11695.8 ORX78319.1 - 1.5e-57 193.2 0.2 1.7e-57 193.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) IN_DBD_C PF00552.21 ORX78319.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 Integrase DNA binding domain ABM PF03992.16 ORX78319.1 - 0.11 12.6 0.7 0.44 10.7 0.1 2.4 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase E1-E2_ATPase PF00122.20 ORX78321.1 - 9.9e-48 162.1 1.4 2.2e-47 160.9 0.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 ORX78321.1 - 1.4e-40 137.6 7.3 7.3e-13 48.8 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 ORX78321.1 - 5.2e-31 108.6 0.2 1.7e-30 106.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_18 PF00704.28 ORX78321.1 - 0.00048 20.0 1.3 1.8 8.2 0.0 3.6 2 1 1 4 4 4 1 Glycosyl hydrolases family 18 Hydrolase_3 PF08282.12 ORX78321.1 - 0.0012 18.7 1.5 0.35 10.6 0.1 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX78321.1 - 0.0027 18.1 0.0 0.0083 16.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase WAK PF08488.11 ORX78321.1 - 0.0059 17.1 0.9 20 5.8 0.2 3.4 1 1 1 3 3 3 0 Wall-associated kinase Hydrolase_6 PF13344.6 ORX78321.1 - 0.022 14.9 0.0 6.7 6.9 0.0 3.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF3071 PF11268.8 ORX78321.1 - 0.024 14.7 0.1 37 4.3 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3071) CoA_binding_2 PF13380.6 ORX78321.1 - 0.078 13.5 0.1 0.81 10.2 0.1 2.6 2 0 0 2 2 2 0 CoA binding domain DUF2774 PF11242.8 ORX78321.1 - 0.2 11.9 0.1 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) DUF996 PF06195.13 ORX78321.1 - 0.65 10.3 4.3 1.9 8.8 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF1461 PF07314.11 ORX78321.1 - 0.82 9.5 4.0 3.1 7.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1461) Fer4_18 PF13746.6 ORX78321.1 - 1.2 9.4 6.9 52 4.1 0.1 4.1 4 0 0 4 4 4 0 4Fe-4S dicluster domain CAP PF00188.26 ORX78322.1 - 7.7e-14 52.6 0.1 1e-13 52.2 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.16 ORX78340.1 - 1.5e-28 99.7 35.5 4e-28 98.4 34.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX78340.1 - 8.1e-09 34.8 27.3 1.4e-08 34.1 11.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 ORX78340.1 - 0.00018 20.4 10.7 0.00018 20.4 10.7 2.2 2 1 0 2 2 2 1 LacY proton/sugar symporter MFS_1_like PF12832.7 ORX78340.1 - 0.0011 18.0 18.0 0.029 13.2 5.5 2.9 2 1 0 2 2 2 2 MFS_1 like family Siva PF05458.12 ORX78341.1 - 9.2e-06 25.4 19.7 6e-05 22.8 18.6 2.0 1 1 1 2 2 2 2 Cd27 binding protein (Siva) RICTOR_N PF14664.6 ORX78342.1 - 1.1e-98 330.7 7.7 1.1e-98 330.7 7.7 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 ORX78342.1 - 2.6e-40 137.2 0.6 6.1e-39 132.8 0.2 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 ORX78342.1 - 1.3e-30 105.5 1.3 1.3e-29 102.2 0.1 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 ORX78342.1 - 4.1e-27 94.0 1.8 5.4e-22 77.5 0.1 6.1 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain Arm PF00514.23 ORX78342.1 - 1.6e-09 37.4 4.0 0.5 10.5 0.0 5.9 4 1 1 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORX78342.1 - 0.0011 19.4 0.3 11 6.5 0.0 3.9 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 ORX78342.1 - 0.011 15.9 2.6 7.1 7.2 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat Tyrosinase PF00264.20 ORX78343.1 - 6.5e-50 170.5 1.9 1.2e-49 169.6 1.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase WD40 PF00400.32 ORX78344.1 - 4.3e-45 150.8 10.1 8.6e-07 29.6 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX78344.1 - 1.2e-14 54.4 0.4 0.15 12.3 0.0 5.5 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX78344.1 - 2e-09 37.6 0.5 2e-05 24.6 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 ORX78344.1 - 6.3e-06 25.9 0.5 0.0001 22.0 0.4 2.2 2 0 0 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.14 ORX78344.1 - 8.4e-05 21.8 0.4 0.16 11.0 0.6 2.1 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 ORX78344.1 - 0.00021 21.1 0.2 0.085 12.8 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ORX78344.1 - 0.00063 19.2 0.0 1.6 8.0 0.0 3.6 2 1 2 4 4 4 1 WD40-like domain Nup160 PF11715.8 ORX78344.1 - 0.00063 18.5 5.3 1.8 7.1 0.0 4.3 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORX78344.1 - 0.0014 17.6 0.1 0.71 8.8 0.0 4.1 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORX78344.1 - 0.0023 16.5 1.7 0.004 15.7 0.6 1.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 ORX78344.1 - 0.028 14.9 1.5 1.3 9.6 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain RBD-FIP PF09457.10 ORX78404.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 FIP domain DUF4179 PF13786.6 ORX78404.1 - 0.15 12.6 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GRP PF07172.11 ORX78405.1 - 4.7 8.0 24.7 3.6 8.3 22.6 1.7 1 1 1 2 2 2 0 Glycine rich protein family DUF1517 PF07466.11 ORX78406.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) GRP PF07172.11 ORX78408.1 - 0.04 14.6 17.4 0.076 13.7 17.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family pKID PF02173.17 ORX78410.1 - 0.11 12.0 2.2 0.52 9.8 1.5 2.3 2 0 0 2 2 2 0 pKID domain GRP PF07172.11 ORX78410.1 - 8.4 7.2 22.9 7.2 7.4 18.2 2.1 2 0 0 2 2 2 0 Glycine rich protein family Ku_N PF03731.15 ORX78449.1 - 1.5e-11 44.5 0.0 1.8e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Transferase PF02458.15 ORX78466.1 - 3.7e-41 141.2 0.0 5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Transferase family Pyr_redox_2 PF07992.14 ORX78469.1 - 1.1e-34 120.0 1.0 1.6e-34 119.5 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX78469.1 - 8.7e-15 55.1 3.1 9e-09 35.8 0.7 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORX78469.1 - 1.5e-07 31.8 1.2 0.00026 21.4 0.0 3.0 3 0 0 3 3 3 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 ORX78469.1 - 2.1e-06 27.8 2.4 0.11 12.4 0.0 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORX78469.1 - 2.1e-06 27.1 0.1 0.0067 15.6 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 ORX78469.1 - 9.3e-05 21.4 4.6 0.53 9.1 0.0 3.6 4 0 0 4 4 4 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORX78469.1 - 9.5e-05 21.8 0.0 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX78469.1 - 0.00042 20.0 4.5 2.2 7.8 0.0 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 ORX78469.1 - 0.0012 18.0 3.6 1.3 8.0 0.0 3.7 2 2 1 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORX78469.1 - 0.016 14.3 3.1 0.16 11.0 0.1 3.2 3 1 1 4 4 4 0 Lycopene cyclase protein TrbI_Ftype PF09677.10 ORX78469.1 - 0.022 15.1 0.5 0.077 13.3 0.0 2.3 3 0 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) NAD_Gly3P_dh_C PF07479.14 ORX78469.1 - 0.094 13.0 0.0 0.31 11.3 0.0 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus TrkA_N PF02254.18 ORX78469.1 - 0.18 12.1 4.7 2.3 8.5 0.1 3.5 3 1 1 4 4 4 0 TrkA-N domain NPHI_C PF08469.10 ORX78497.1 - 0.00074 19.5 0.2 0.0016 18.4 0.2 1.7 1 1 0 1 1 1 1 Nucleoside triphosphatase I C-terminal DNA_pol_B_exo1 PF03104.19 ORX78498.1 - 2.5e-10 40.0 1.3 3.4e-10 39.6 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_3 PF08408.10 ORX78498.1 - 0.00066 19.9 0.3 0.0011 19.2 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B viral insert DNA_pol_A_exo1 PF01612.20 ORX78498.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease FANCI_S1 PF14675.6 ORX78498.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 1 HIRAN PF08797.11 ORX78499.1 - 7.6e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain MutS_V PF00488.21 ORX78500.1 - 2.9e-39 135.1 0.1 5.7e-39 134.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORX78500.1 - 1.3e-14 54.8 2.5 3.3e-14 53.6 2.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORX78500.1 - 8.8e-11 42.0 0.0 2.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 ORX78500.1 - 6.8e-05 23.1 0.4 0.0002 21.6 0.4 1.9 1 0 0 1 1 1 1 MutS family domain IV HNH PF01844.23 ORX78500.1 - 0.0064 16.6 11.8 0.0064 16.6 11.8 2.5 2 0 0 2 2 2 1 HNH endonuclease Exonuc_VII_L PF02601.15 ORX78501.1 - 1.5 8.3 7.2 1.9 8.0 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4404 PF14357.6 ORX78501.1 - 1.7 9.3 6.1 1.4 9.6 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RNA_polI_A14 PF08203.11 ORX78501.1 - 6.4 7.6 7.0 2 9.2 3.2 2.2 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Spore_YpjB PF09577.10 ORX78502.1 - 0.0066 16.3 1.2 0.018 14.9 1.2 1.7 1 1 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) UPF0449 PF15136.6 ORX78502.1 - 0.016 15.7 1.0 0.028 14.9 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Exonuc_VII_L PF02601.15 ORX78502.1 - 0.15 11.6 2.3 0.17 11.4 2.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Myb_DNA-bind_4 PF13837.6 ORX78502.1 - 1.4 9.4 7.2 0.76 10.2 1.8 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Fib_alpha PF08702.10 ORX78502.1 - 1.7 8.9 7.5 2.9 8.1 7.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF573 PF04504.14 ORX78502.1 - 1.9 9.2 7.9 0.96 10.1 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DBR1 PF05011.13 ORX78503.1 - 0.016 15.6 3.7 0.022 15.2 3.7 1.1 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain FapA PF03961.13 ORX78503.1 - 0.26 9.9 8.8 0.37 9.4 8.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 ORX78503.1 - 0.35 10.4 4.3 0.49 9.9 4.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MinE PF03776.14 ORX78503.1 - 0.8 9.8 6.0 0.62 10.1 1.9 2.7 1 1 2 3 3 3 0 Septum formation topological specificity factor MinE WRC PF08879.10 ORX78504.1 - 0.017 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 WRC zf-TRM13_CCCH PF11722.8 ORX78504.1 - 0.16 11.7 1.4 0.29 10.9 1.4 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein PTR2 PF00854.21 ORX78505.1 - 1.4e-74 251.3 8.7 2.5e-74 250.5 8.6 1.4 1 1 0 1 1 1 1 POT family Glycos_transf_2 PF00535.26 ORX78552.1 - 0.00029 20.7 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORX78552.1 - 0.00073 19.5 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX78552.1 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 BAG PF02179.16 ORX78553.1 - 0.019 15.4 1.9 0.019 15.4 1.9 2.4 2 2 0 2 2 2 0 BAG domain DUF2116 PF09889.9 ORX78553.1 - 0.18 11.8 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) IZUMO PF15005.6 ORX78553.1 - 1.4 9.5 4.2 15 6.1 0.1 2.7 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated SNARE PF05739.19 ORX78554.1 - 2.1e-16 59.7 0.5 2.1e-16 59.7 0.5 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 ORX78554.1 - 4e-06 25.9 0.2 8.7e-06 24.8 0.2 1.6 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain SF-assemblin PF06705.11 ORX78554.1 - 0.00017 21.0 8.8 0.0011 18.4 4.1 2.2 2 0 0 2 2 2 1 SF-assemblin/beta giardin FlxA PF14282.6 ORX78554.1 - 0.0095 15.9 3.1 0.0095 15.9 3.1 2.6 2 1 0 2 2 2 1 FlxA-like protein DUF4094 PF13334.6 ORX78554.1 - 0.051 14.0 3.6 0.39 11.2 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) NPV_P10 PF05531.12 ORX78554.1 - 0.052 14.0 9.4 0.098 13.1 2.1 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 ORX78554.1 - 0.076 13.6 8.0 0.97 10.0 1.5 2.6 3 1 0 3 3 2 0 Syntaxin 6, N-terminal CCDC84 PF14968.6 ORX78554.1 - 0.097 12.3 4.4 0.14 11.8 4.4 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 DUF4337 PF14235.6 ORX78554.1 - 0.13 12.3 4.2 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.11 ORX78554.1 - 0.3 11.5 5.9 0.42 11.1 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tweety PF04906.13 ORX78554.1 - 0.46 9.1 9.7 0.29 9.7 0.6 2.9 2 1 1 3 3 3 0 Tweety Osmo_CC PF08946.10 ORX78554.1 - 0.46 10.8 3.4 37 4.7 0.3 3.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil EMP24_GP25L PF01105.24 ORX78554.1 - 0.6 10.0 6.0 0.62 10.0 0.4 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.12 ORX78554.1 - 0.93 10.1 7.6 0.91 10.2 1.2 2.9 2 1 0 2 2 2 0 SlyX DUF1664 PF07889.12 ORX78554.1 - 1.1 9.3 7.8 3.8 7.6 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) AI-2E_transport PF01594.16 ORX78554.1 - 1.6 7.8 7.9 3.3 6.8 1.3 2.1 2 0 0 2 2 2 0 AI-2E family transporter DUF724 PF05266.14 ORX78554.1 - 1.8 8.3 11.1 0.78 9.5 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 ORX78554.1 - 2.1 7.5 8.3 3.4 6.8 4.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF2570 PF10828.8 ORX78554.1 - 2.1 8.2 8.8 0.21 11.4 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Syntaxin PF00804.25 ORX78554.1 - 7 6.3 14.2 1.8 8.2 9.6 2.1 2 1 0 2 2 2 0 Syntaxin Ribosomal_L21e PF01157.18 ORX78555.1 - 1.4e-47 159.7 5.5 1.4e-47 159.7 5.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e S4 PF01479.25 ORX78556.1 - 1e-12 47.5 1.0 1e-12 47.5 1.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORX78556.1 - 4.1e-05 24.4 0.1 9.1e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Myb_DNA-binding PF00249.31 ORX78557.1 - 3.3e-05 24.0 0.6 0.00027 21.1 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX78557.1 - 0.00091 19.4 0.1 0.1 12.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF383 PF04063.14 ORX78558.1 - 6.2e-70 234.8 0.4 2.1e-69 233.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 ORX78558.1 - 9.7e-22 76.6 0.2 2.3e-21 75.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Dcc1 PF09724.9 ORX78558.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 PDCD7 PF16021.5 ORX78559.1 - 9.7e-33 113.6 43.6 2e-32 112.6 41.2 2.4 1 1 1 2 2 2 1 Programmed cell death protein 7 Filament PF00038.21 ORX78559.1 - 0.78 9.3 32.2 2.2 7.8 31.7 1.9 1 1 0 1 1 1 0 Intermediate filament protein RPN1_RPN2_N PF17781.1 ORX78559.1 - 0.84 9.0 12.4 0.17 11.2 6.6 2.3 2 1 0 2 2 2 0 RPN1/RPN2 N-terminal domain DUF1843 PF08898.10 ORX78559.1 - 1.3 9.6 5.5 12 6.5 1.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) OmpH PF03938.14 ORX78559.1 - 2.3 8.6 34.1 3 8.2 15.9 3.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) FAD_binding_3 PF01494.19 ORX78560.1 - 1.1e-20 74.3 0.6 1.2e-09 37.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORX78560.1 - 0.0001 22.0 0.3 0.00065 19.4 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 ORX78560.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 ORX78560.1 - 0.0094 15.2 0.1 0.18 11.0 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX78560.1 - 0.016 15.4 0.2 0.046 13.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORX78560.1 - 0.018 14.0 0.0 0.37 9.6 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ORX78560.1 - 0.068 12.2 0.3 2.3 7.2 0.2 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein YABBY PF04690.13 ORX78561.1 - 5.7e-10 40.0 0.3 5.7e-10 40.0 0.3 1.9 1 1 1 2 2 2 1 YABBY protein Ccdc124 PF06244.12 ORX78561.1 - 1.4e-05 25.7 0.4 1.4e-05 25.7 0.4 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORX78561.1 - 0.00012 22.4 3.9 0.00021 21.6 3.9 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box DOG1 PF14144.6 ORX78561.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Seed dormancy control GPI-anchored PF10342.9 ORX78562.1 - 1.2e-10 42.0 0.0 2.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Endosulfine PF04667.17 ORX78563.1 - 1.8e-27 95.3 0.1 2.9e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Glyoxalase PF00903.25 ORX78564.1 - 1.6e-25 89.8 0.0 1.8e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORX78564.1 - 4.7e-06 26.8 0.0 3.4e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORX78564.1 - 6.2e-06 27.0 0.0 1.1e-05 26.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ORX78564.1 - 0.00025 21.0 0.0 0.22 11.5 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 ORX78564.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Mito_carr PF00153.27 ORX78565.1 - 5.5e-74 244.2 3.9 2.6e-24 85.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX78565.1 - 0.2 10.8 3.2 1.3 8.2 0.3 2.9 1 1 3 4 4 4 0 Gammaproteobacterial serine protease Vac_ImportDeg PF09783.9 ORX78593.1 - 4.6e-45 153.3 0.0 6.3e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF848 PF05852.11 ORX78593.1 - 2.1 8.4 4.6 4.3 7.4 4.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PIN7 PF18475.1 ORX78595.1 - 0.038 14.6 0.1 0.053 14.2 0.1 1.3 1 1 0 1 1 1 0 PIN domain DUF1963 PF09234.10 ORX78596.1 - 6.2e-15 56.2 0.0 8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) UCH PF00443.29 ORX78648.1 - 1e-55 189.0 0.0 3.8e-55 187.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX78648.1 - 2.1e-28 99.9 6.0 7.1e-23 81.7 0.8 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORX78648.1 - 0.0085 15.6 9.7 1.7 8.1 7.0 3.5 2 1 1 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase SpoIIID PF12116.8 ORX78648.1 - 0.026 14.6 0.0 0.076 13.1 0.0 1.7 2 0 0 2 2 2 0 Stage III sporulation protein D SPATIAL PF15256.6 ORX78648.1 - 0.086 13.2 1.7 3.1 8.1 0.0 2.5 2 0 0 2 2 2 0 SPATIAL SURF4 PF02077.15 ORX78649.1 - 5e-95 318.1 12.5 5.7e-95 317.9 12.5 1.0 1 0 0 1 1 1 1 SURF4 family HLH PF00010.26 ORX78650.1 - 4.8e-11 42.4 0.5 9.5e-11 41.5 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MAPEG PF01124.18 ORX78651.1 - 8.2e-18 64.6 0.6 9.7e-18 64.3 0.6 1.0 1 0 0 1 1 1 1 MAPEG family Neprosin PF03080.15 ORX78651.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Neprosin Asp PF00026.23 ORX78652.1 - 4.1e-108 361.5 0.0 4.9e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX78652.1 - 3.2e-14 53.6 0.3 2.3e-11 44.3 0.3 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX78652.1 - 2.6e-06 27.3 0.0 8.6e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORX78652.1 - 5.9e-05 23.6 0.1 0.23 12.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORX78652.1 - 0.01 16.4 0.0 7.7 7.2 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease YCII PF03795.14 ORX78653.1 - 3.7e-13 49.7 0.0 4.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.14 ORX78654.1 - 9.1e-12 45.2 0.1 1.3e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 YCII-related domain CBFD_NFYB_HMF PF00808.23 ORX78655.1 - 1.3e-16 60.6 1.5 1.7e-16 60.2 1.5 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX78655.1 - 0.00091 19.6 0.4 0.00091 19.6 0.4 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 p450 PF00067.22 ORX78656.1 - 5.4e-77 259.5 0.0 1.3e-76 258.3 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORX78656.1 - 2.2e-31 109.2 0.0 3.6e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX78656.1 - 6.5e-23 81.5 0.0 1.4e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORX78656.1 - 6.3e-14 52.5 0.0 2.6e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF3072 PF11272.8 ORX78656.1 - 0.18 11.8 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Arrestin_C PF02752.22 ORX78658.1 - 1.7e-09 38.2 0.0 3.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX78658.1 - 6.7e-07 29.5 0.0 6.2e-05 23.1 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PUF PF00806.19 ORX78696.1 - 1.6e-68 222.7 13.9 2.9e-08 32.9 0.1 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 ORX78696.1 - 0.042 13.7 2.3 9.2 6.1 0.0 4.3 5 0 0 5 5 5 0 Single Cache domain 2 RhoGEF PF00621.20 ORX78698.1 - 6.3e-32 111.3 0.5 1.5e-31 110.0 0.1 2.0 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.11 ORX78698.1 - 1.1e-30 105.7 0.1 2.4e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 ORX78698.1 - 1.4e-17 63.3 0.3 5.8e-17 61.4 0.3 2.1 1 0 0 1 1 1 1 PB1 domain PH_10 PF15411.6 ORX78698.1 - 1.6e-14 54.2 0.0 4.7e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain MMR_HSR1_C PF08438.10 ORX78698.1 - 0.049 14.2 0.6 0.16 12.6 0.2 2.2 2 0 0 2 2 2 0 GTPase of unknown function C-terminal PH PF00169.29 ORX78698.1 - 0.061 13.8 0.1 0.17 12.4 0.1 1.7 1 0 0 1 1 1 0 PH domain Proteasome PF00227.26 ORX78700.1 - 2.5e-49 167.4 0.0 3e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORX78700.1 - 7.2e-13 48.0 0.0 1.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chitin_synth_2 PF03142.15 ORX78701.1 - 6.9e-106 354.9 0.3 9.2e-106 354.5 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 ORX78701.1 - 1.1e-08 35.1 0.0 0.0032 17.6 0.1 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ORX78701.1 - 2.1e-06 27.8 6.0 6.5e-06 26.2 6.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX78701.1 - 3.1e-05 23.8 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORX78701.1 - 6.2e-05 23.0 0.0 0.0006 19.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX78701.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Peptidase_M18 PF02127.15 ORX78702.1 - 2.6e-164 547.1 0.2 3.7e-164 546.6 0.2 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORX78702.1 - 4.8e-08 32.4 0.5 3.8e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase LTV PF04180.14 ORX78703.1 - 2.7e-71 241.3 22.3 9.5e-54 183.6 8.8 2.0 1 1 1 2 2 2 2 Low temperature viability protein DUF3907 PF13047.6 ORX78703.1 - 0.017 15.1 1.3 0.055 13.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) DUF948 PF06103.11 ORX78731.1 - 0.43 10.9 7.4 0.67 10.3 7.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Endostatin PF06482.11 ORX78731.1 - 1.4 8.3 6.2 3.7 6.9 6.2 1.6 1 1 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2554 PF10829.8 ORX78737.1 - 0.038 14.4 0.2 0.09 13.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2554) RPA43_OB PF17875.1 ORX78738.1 - 0.04 14.5 0.0 0.068 13.8 0.0 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF5077 PF16871.5 ORX78739.1 - 0.00059 19.8 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF3472 PF11958.8 ORX78739.1 - 0.0053 17.2 0.2 0.0082 16.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF4377 PF14302.6 ORX78739.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) DUF3472 PF11958.8 ORX78740.1 - 4.9e-09 36.9 0.1 6.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX78740.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) CsbD PF05532.12 ORX78768.1 - 1.8e-22 79.0 17.5 5.3e-12 45.5 7.3 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78769.1 - 6.4e-22 77.2 18.2 7e-12 45.1 6.3 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78770.1 - 1.5e-22 79.2 16.2 4.2e-12 45.8 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78771.1 - 1.3e-22 79.4 17.2 5e-12 45.5 7.2 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78772.1 - 1.8e-22 79.0 17.5 5.3e-12 45.5 7.3 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78773.1 - 2.5e-22 78.5 17.9 6.8e-12 45.1 7.6 2.0 1 1 1 2 2 2 2 CsbD-like Lipocalin_2 PF08212.12 ORX78773.1 - 1.3 8.9 3.7 6.5 6.7 0.6 2.1 1 1 1 2 2 2 0 Lipocalin-like domain CsbD PF05532.12 ORX78774.1 - 1.8e-22 79.0 17.5 4.9e-12 45.6 7.2 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78775.1 - 1.8e-22 79.0 20.8 5.7e-12 45.4 6.4 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX78776.1 - 2.1e-23 82.0 18.7 1.4e-12 47.3 5.1 2.0 1 1 1 2 2 2 2 CsbD-like ThrE PF06738.12 ORX78797.1 - 2.8e-57 193.9 15.6 1.2e-51 175.4 2.7 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORX78797.1 - 4.6e-07 30.0 23.8 0.00023 21.3 6.9 2.6 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE Sel1 PF08238.12 ORX78798.1 - 7.4e-26 90.0 22.9 1.7e-06 28.5 0.2 7.8 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 ORX78798.1 - 0.0011 19.1 2.3 4 7.7 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORX78798.1 - 0.11 12.5 0.4 5.5 7.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat QueH PF02677.14 ORX78798.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH TPR_6 PF13174.6 ORX78798.1 - 0.16 12.6 10.1 46 4.9 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORX78798.1 - 0.25 12.0 2.3 1.3 9.7 0.0 3.4 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX78798.1 - 9.5 6.6 13.4 1.6 9.0 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Svf1_C PF17187.4 ORX78799.1 - 9.4e-37 126.4 0.1 1.4e-36 125.8 0.1 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORX78799.1 - 2.1e-17 63.7 0.1 3.8e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain zf-C2H2 PF00096.26 ORX78800.1 - 1.2e-09 38.1 7.7 9.8e-06 25.7 1.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX78800.1 - 1.3e-07 31.7 11.2 1.5e-07 31.5 0.9 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX78800.1 - 6.7e-07 29.6 6.5 0.0097 16.7 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORX78800.1 - 0.00022 21.8 0.7 0.099 13.3 0.0 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX78800.1 - 0.0075 16.5 0.7 0.027 14.7 0.6 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORX78800.1 - 0.022 14.9 1.0 0.027 14.6 1.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger OrsD PF12013.8 ORX78800.1 - 0.037 14.5 1.9 3.4 8.2 0.1 2.0 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Exo_endo_phos PF03372.23 ORX78801.1 - 8.2e-08 32.0 0.1 1.7e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GATase_7 PF13537.6 ORX78801.1 - 0.071 13.0 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain Nucleos_tra2_C PF07662.13 ORX78823.1 - 4.5e-75 252.0 6.8 4.5e-75 252.0 6.8 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX78823.1 - 5.1e-23 81.5 4.7 5.1e-23 81.5 4.7 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX78823.1 - 0.0035 17.6 8.4 0.0035 17.6 8.4 4.2 3 2 0 3 3 3 2 Nucleoside recognition Glyco_hydro_9 PF00759.19 ORX78850.1 - 4.9e-124 414.9 13.3 5.6e-124 414.7 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PsbN PF02468.15 ORX78850.1 - 5.9 6.8 5.5 13 5.7 5.5 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Kelch_5 PF13854.6 ORX78851.1 - 2.1e-22 78.6 2.3 0.00082 19.3 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 ORX78851.1 - 3.3e-21 74.4 1.7 0.00029 20.7 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 ORX78851.1 - 4e-21 74.8 18.7 7.4e-06 26.1 0.0 7.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 ORX78851.1 - 2e-17 62.9 10.7 2.6e-05 24.1 0.1 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX78851.1 - 1.6e-16 59.9 10.3 9.5e-05 22.5 0.1 6.4 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 ORX78851.1 - 2.8e-13 49.2 1.2 0.00064 19.3 0.0 5.6 6 0 0 6 6 6 4 Kelch motif zf-C2H2 PF00096.26 ORX78852.1 - 2.4e-11 43.4 12.2 2.5e-06 27.6 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX78852.1 - 9.8e-07 29.1 10.0 0.0004 21.0 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX78852.1 - 5.6e-05 23.4 3.4 5.6e-05 23.4 3.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORX78852.1 - 0.00054 20.2 0.5 0.0018 18.5 0.5 1.8 1 1 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORX78852.1 - 0.00082 20.0 3.5 0.36 11.5 0.2 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORX78852.1 - 0.004 17.1 1.3 0.004 17.1 1.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORX78852.1 - 0.019 15.1 2.1 3.8 7.6 0.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger N36 PF11438.8 ORX78852.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) CHORD PF04968.12 ORX78852.1 - 0.25 12.1 3.5 0.51 11.1 0.7 2.2 1 1 1 2 2 2 0 CHORD zf-met PF12874.7 ORX78852.1 - 1.7 9.2 4.8 19 5.8 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORX78853.1 - 5.9e-07 29.6 17.0 0.00066 20.0 2.0 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX78853.1 - 1.6e-05 25.3 11.8 0.0017 19.0 1.0 2.8 2 1 1 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORX78853.1 - 0.00055 20.5 3.3 0.097 13.3 0.1 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORX78853.1 - 0.0009 19.6 5.4 0.0009 19.6 5.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX78853.1 - 0.0015 18.4 0.5 0.0015 18.4 0.5 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX78853.1 - 0.41 10.4 7.8 1.3 8.9 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain CHORD PF04968.12 ORX78853.1 - 1.4 9.7 7.9 0.4 11.4 0.6 3.0 3 1 0 3 3 3 0 CHORD His_Phos_2 PF00328.22 ORX78854.1 - 1.2e-81 275.1 0.1 1.5e-81 274.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ORX78854.1 - 3.6e-40 136.0 0.0 7.6e-40 135.0 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ORX78854.1 - 1e-07 31.7 0.2 3.7e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ORX78854.1 - 0.0031 17.6 0.2 0.0088 16.1 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF1818 PF08848.11 ORX78854.1 - 0.14 12.3 0.0 0.72 10.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1818) Abhydrolase_1 PF00561.20 ORX78855.1 - 8.9e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX78855.1 - 8.2e-06 25.3 0.0 1.8e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX78855.1 - 0.005 17.5 0.0 0.007 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Nse4_C PF08743.10 ORX78856.1 - 3.2e-31 107.4 0.9 9.9e-30 102.7 0.0 2.5 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 ORX78856.1 - 1.3e-13 50.8 0.5 2.8e-13 49.7 0.1 1.8 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DDE_Tnp_1_7 PF13843.6 ORX78883.1 - 0.0053 16.1 0.4 0.0071 15.7 0.4 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 ORX78884.1 - 0.046 13.0 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 ATP-synt_ab PF00006.25 ORX78907.1 - 7.7e-62 208.7 0.0 1.2e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX78907.1 - 3.1e-22 78.8 0.9 7.1e-22 77.7 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ORX78907.1 - 0.015 14.7 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ORX78907.1 - 0.026 13.7 0.8 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 ORX78907.1 - 0.059 13.7 0.8 0.45 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORX78907.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORX78907.1 - 0.069 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORX78907.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Med2 PF11214.8 ORX78907.1 - 0.14 12.4 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 RNA_helicase PF00910.22 ORX78907.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arf PF00025.21 ORX78908.1 - 4.4e-18 65.3 0.1 4.9e-18 65.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 ORX78908.1 - 0.049 12.6 0.0 0.056 12.4 0.0 1.0 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 ORX78938.1 - 3.4e-58 196.0 0.0 1.5e-27 96.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ORX78938.1 - 4.1e-27 95.2 22.5 4.1e-27 95.2 22.5 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX78938.1 - 4.3e-20 72.7 1.5 4.1e-06 26.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 ORX78938.1 - 6.2e-06 26.2 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 ORX78938.1 - 6.7e-05 22.8 0.3 0.68 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 ORX78938.1 - 0.0019 17.7 0.0 8.2 5.8 0.0 3.5 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX78938.1 - 0.0019 18.1 0.3 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 ORX78938.1 - 0.002 18.7 3.7 0.52 10.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 ORX78938.1 - 0.0023 17.3 0.0 4.7 6.5 0.0 3.4 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORX78938.1 - 0.0086 15.8 1.4 0.93 9.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 ORX78938.1 - 0.016 15.4 0.0 0.43 10.9 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ORX78938.1 - 0.026 14.7 0.3 3.1 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4162 PF13732.6 ORX78938.1 - 0.029 15.1 0.0 3.7 8.3 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_16 PF13191.6 ORX78938.1 - 0.053 13.9 0.2 8.7 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 ORX78938.1 - 0.22 11.1 2.3 11 5.6 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PAS_9 PF13426.7 ORX78940.1 - 1.5e-27 95.8 0.0 1.8e-14 53.9 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ORX78940.1 - 5.4e-21 74.7 0.0 1.1e-10 41.6 0.0 4.4 5 0 0 5 5 5 3 PAS fold PAS PF00989.25 ORX78940.1 - 9.9e-14 51.3 0.0 1.5e-06 28.2 0.0 3.9 3 1 0 3 3 3 2 PAS fold GATA PF00320.27 ORX78940.1 - 1.9e-12 46.5 4.9 3.6e-12 45.7 4.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 ORX78940.1 - 5.4e-10 39.4 0.0 9.5e-06 25.7 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 ORX78940.1 - 2.5e-07 30.9 0.0 0.0015 18.7 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 ORX78940.1 - 0.0022 18.7 0.2 4.1 8.1 0.1 3.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ORX78940.1 - 0.075 13.1 0.0 1.5 8.9 0.0 2.9 3 1 1 4 4 4 0 PAS domain SPDY PF03771.16 ORX78941.1 - 0.012 15.6 0.5 0.16 12.0 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF317) TBCA PF02970.16 ORX78943.1 - 3.4e-28 97.8 6.9 4.3e-28 97.5 6.9 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Bul1_N PF04425.12 ORX78943.1 - 0.036 12.8 1.4 0.042 12.6 1.4 1.1 1 0 0 1 1 1 0 Bul1 N terminus CAF1 PF04857.20 ORX78943.1 - 0.19 10.9 1.7 0.22 10.7 1.7 1.0 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF1640 PF07798.11 ORX78944.1 - 3.7e-47 160.6 8.8 4.7e-47 160.3 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SHE3 PF17078.5 ORX78944.1 - 0.031 14.0 7.4 0.1 12.3 7.5 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Baculo_PEP_C PF04513.12 ORX78944.1 - 0.1 12.6 1.1 2.9 7.9 0.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_lysis PF03245.13 ORX78944.1 - 0.12 12.5 2.0 0.22 11.6 1.1 1.8 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein APG6_N PF17675.1 ORX78944.1 - 0.14 12.7 9.9 0.21 12.1 9.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 ORX78944.1 - 0.76 10.4 7.1 0.6 10.7 1.8 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 ORX78944.1 - 4.3 7.8 9.8 7 7.1 0.3 3.8 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Nup54 PF13874.6 ORX78944.1 - 6.7 6.8 8.5 25 4.9 4.8 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 adh_short_C2 PF13561.6 ORX78946.1 - 1.9e-67 227.2 1.5 2.2e-67 227.0 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX78946.1 - 1.2e-54 184.7 2.2 1.5e-54 184.5 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX78946.1 - 4.9e-15 55.9 1.1 6.5e-15 55.5 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX78946.1 - 2.8e-08 33.5 1.2 9.5e-08 31.8 1.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX78946.1 - 2.8e-05 23.4 1.3 3.6e-05 23.1 1.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORX78946.1 - 0.0026 17.2 2.0 0.057 12.8 2.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 ORX78946.1 - 0.015 14.6 0.1 0.032 13.5 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain B12-binding PF02310.19 ORX78946.1 - 0.035 14.1 0.2 0.058 13.4 0.2 1.4 1 0 0 1 1 1 0 B12 binding domain Pyr_redox_2 PF07992.14 ORX78947.1 - 7.8e-19 68.0 0.0 2.6e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX78947.1 - 0.00099 19.6 0.4 0.32 11.6 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX78947.1 - 0.0093 16.0 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX78947.1 - 0.012 14.7 0.0 0.039 13.0 0.0 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 ORX78947.1 - 0.012 15.2 0.2 2.8 7.4 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX78947.1 - 0.029 13.6 0.1 3.2 6.9 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX78947.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 ORX78947.1 - 0.17 11.1 0.1 0.34 10.1 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Ribosomal_S27e PF01667.17 ORX78948.1 - 1.2e-29 101.7 4.9 1.5e-29 101.5 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORX78948.1 - 0.16 11.5 3.2 0.24 10.9 3.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Mito_carr PF00153.27 ORX78949.1 - 5.4e-66 218.6 0.7 2.1e-21 75.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMA PF00403.26 ORX78950.1 - 2e-16 60.2 2.2 2.2e-16 60.1 2.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 ORX78950.1 - 0.015 15.6 0.3 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain NapD PF03927.13 ORX78950.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 NapD protein BON PF04972.17 ORX78950.1 - 0.023 15.0 0.7 0.031 14.6 0.7 1.3 1 0 0 1 1 1 0 BON domain HSP20 PF00011.21 ORX78950.1 - 0.057 13.6 0.4 0.078 13.1 0.4 1.5 1 1 0 1 1 1 0 Hsp20/alpha crystallin family Aminotran_1_2 PF00155.21 ORX78951.1 - 4.9e-51 174.0 0.0 5.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX78951.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORX78951.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 ORX78973.1 - 3.8e-74 249.4 0.0 5.6e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX78973.1 - 9.1e-43 146.4 0.0 1.3e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX78973.1 - 2.4e-06 27.1 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX78973.1 - 0.00033 19.7 0.6 0.00058 18.9 0.6 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX78973.1 - 0.0038 17.2 0.1 0.013 15.4 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX78973.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 ORX78973.1 - 0.062 12.6 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_31 PF01055.26 ORX78974.1 - 1.5e-160 535.2 3.9 2.3e-160 534.6 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORX78974.1 - 9.2e-33 112.9 0.1 1.7e-32 112.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORX78974.1 - 4.7e-09 36.4 0.1 2.3e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like GHL15 PF14885.6 ORX78974.1 - 0.11 12.5 1.1 0.19 11.7 1.1 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Aldedh PF00171.22 ORX78975.1 - 1.9e-168 560.8 1.6 2.1e-168 560.6 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORX78975.1 - 0.00014 21.4 0.0 0.00039 19.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) YCII PF03795.14 ORX78975.1 - 0.12 12.7 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 YCII-related domain Cecropin PF00272.19 ORX78975.1 - 0.88 9.3 3.9 0.35 10.6 0.2 2.4 2 0 0 2 2 2 0 Cecropin family CLZ PF16526.5 ORX78976.1 - 0.0098 16.2 0.7 5.8 7.3 0.3 2.4 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DNA_mis_repair PF01119.19 ORX78978.1 - 6.2e-14 51.7 0.1 2.6e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORX78978.1 - 9e-11 41.7 0.1 2.2e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORX78978.1 - 5e-08 33.4 0.2 1.9e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TGT PF01702.18 ORX78979.1 - 6.3e-152 505.7 0.0 7.7e-152 505.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Phage_tail_T PF06223.12 ORX78980.1 - 0.15 12.6 0.5 0.94 10.0 0.1 2.3 3 0 0 3 3 3 0 Minor tail protein T DUF3824 PF12868.7 ORX78980.1 - 0.23 12.1 2.1 0.82 10.3 2.1 1.8 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) WD40 PF00400.32 ORX79001.1 - 2.9e-41 138.7 20.6 1.6e-05 25.5 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORX79001.1 - 4.9e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX79001.1 - 3.7e-07 30.4 2.0 1.5 9.2 0.0 5.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX79001.1 - 4.9e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 ORX79001.1 - 1.1e-05 25.5 0.2 0.3 11.1 0.0 4.2 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 ORX79001.1 - 0.0068 15.1 5.8 11 4.5 0.0 5.3 3 1 1 6 6 6 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ORX79001.1 - 0.0096 15.5 0.6 2.8 7.4 0.0 3.1 2 1 2 4 4 4 1 PQQ-like domain WD40_like PF17005.5 ORX79001.1 - 0.014 14.7 0.1 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 ORX79001.1 - 0.036 13.0 0.8 6.8 5.5 0.1 3.2 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain F-box_4 PF15966.5 ORX79001.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box NtA PF03146.15 ORX79001.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Agrin NtA domain DUF2255 PF10012.9 ORX79001.1 - 0.081 13.1 0.2 0.43 10.8 0.1 2.3 2 0 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2255) PQQ PF01011.21 ORX79001.1 - 0.21 11.6 0.5 2.7 8.1 0.1 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat WD40 PF00400.32 ORX79002.1 - 3.1e-49 163.9 22.8 2.6e-07 31.2 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 ORX79002.1 - 1.6e-13 50.3 0.0 3.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX79002.1 - 5.1e-10 39.5 2.5 0.051 13.9 0.1 5.5 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX79002.1 - 7.1e-09 35.3 0.1 1.4e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORX79002.1 - 7.8e-09 34.7 3.9 0.16 10.6 0.0 5.8 2 2 4 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ORX79002.1 - 2.9e-08 33.4 3.2 2.1e-05 24.0 0.8 2.1 1 1 1 2 2 2 2 WD40-like domain DUF5046 PF16465.5 ORX79002.1 - 4.5e-05 23.0 0.0 0.13 11.6 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 ORX79002.1 - 0.0037 16.9 0.5 0.93 9.0 0.1 3.3 1 1 1 3 3 3 1 PQQ-like domain PALB2_WD40 PF16756.5 ORX79002.1 - 0.0046 15.9 3.1 3.2 6.6 0.0 4.5 1 1 4 6 6 6 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 ORX79002.1 - 0.1 12.4 0.0 4.2 7.2 0.0 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PNP_UDP_1 PF01048.20 ORX79027.1 - 4.7e-45 153.7 0.1 6.3e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Arrestin_C PF02752.22 ORX79028.1 - 3.5e-08 34.0 0.9 1.2e-06 29.0 0.1 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX79028.1 - 5.2e-05 23.3 0.1 0.00082 19.4 0.0 2.2 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PseudoU_synth_2 PF00849.22 ORX79030.1 - 6.7e-29 101.0 0.0 9.3e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ORX79030.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 S4 domain DUF756 PF05506.12 ORX79031.1 - 0.061 14.2 0.2 0.078 13.9 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF756) U-box PF04564.15 ORX79032.1 - 5.4e-07 29.7 0.1 2e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 ORX79032.1 - 1.4e-06 28.3 0.1 4.1e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 ORX79032.1 - 6.2e-06 25.8 0.0 2.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 ORX79032.1 - 0.0036 17.1 0.6 0.093 12.6 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SBP_bac_6 PF13343.6 ORX79032.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein MFS_1 PF07690.16 ORX79086.1 - 9.2e-53 179.4 49.3 9.2e-53 179.4 49.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX79086.1 - 2.8e-16 59.4 12.3 2.8e-16 59.4 12.3 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORX79086.1 - 1.4e-15 56.7 29.2 1.8e-15 56.4 29.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ROK PF00480.20 ORX79086.1 - 0.92 8.9 6.8 0.67 9.4 0.1 2.6 2 1 1 3 3 3 0 ROK family DUF3472 PF11958.8 ORX79087.1 - 1.1e-12 48.8 1.9 1.6e-12 48.2 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX79087.1 - 7e-08 32.8 12.8 1.4e-07 31.8 12.8 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORX79087.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) DUF4937 PF16291.5 ORX79087.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 DUF3472 PF11958.8 ORX79088.1 - 7.2e-12 46.1 5.9 1.2e-11 45.4 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX79088.1 - 0.0035 17.2 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) vATP-synt_AC39 PF01992.16 ORX79110.1 - 3.9e-121 404.7 0.7 4.3e-121 404.5 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Chromo_shadow PF01393.19 ORX79111.1 - 3.9e-19 68.5 1.6 5.7e-16 58.4 0.1 2.7 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 ORX79111.1 - 5.5e-18 64.6 3.9 5.5e-18 64.6 3.9 3.1 3 1 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C92 PF05708.12 ORX79111.1 - 0.057 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Mtf2_C PF14061.6 ORX79111.1 - 0.068 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Arrestin_N PF00339.29 ORX79112.1 - 4.1e-12 46.4 0.0 1.9e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX79112.1 - 8e-12 45.8 0.1 7.3e-11 42.7 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX79112.1 - 0.00016 21.5 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Abhydrolase_1 PF00561.20 ORX79113.1 - 3.5e-18 66.2 0.2 4.4e-17 62.6 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX79113.1 - 5.8e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX79113.1 - 1.9e-12 48.2 0.0 3.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX79113.1 - 0.0062 16.0 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Vac_ImportDeg PF09783.9 ORX79114.1 - 5.8e-17 62.0 0.0 6.3e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Vac_ImportDeg PF09783.9 ORX79115.1 - 2.2e-17 63.3 0.3 2.3e-17 63.3 0.3 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein p450 PF00067.22 ORX79133.1 - 8.8e-43 146.7 0.1 1.9e-40 139.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 CBM_19 PF03427.13 ORX79134.1 - 0.00046 20.1 0.6 0.00077 19.4 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) Collagen PF01391.18 ORX79136.1 - 3.3e-31 106.8 92.8 3.6e-09 36.3 19.1 5.2 3 1 2 5 5 5 2 Collagen triple helix repeat (20 copies) CBM_19 PF03427.13 ORX79136.1 - 0.02 14.9 2.2 0.031 14.3 2.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) COX6B PF02297.17 ORX79165.1 - 6.1e-12 45.6 0.8 7.8e-12 45.3 0.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Y_phosphatase2 PF03162.13 ORX79166.1 - 4.1e-62 208.6 0.1 4.5e-62 208.5 0.1 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORX79166.1 - 2.9e-06 27.4 0.0 4.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORX79166.1 - 3.6e-05 23.6 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX79166.1 - 0.03 13.9 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Dfp1_Him1_M PF08630.10 ORX79167.1 - 2.5e-22 79.4 0.0 5.8e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 ORX79167.1 - 5.9e-16 58.3 0.7 1.4e-15 57.1 0.7 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 ORX79167.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORX79167.1 - 0.00082 19.3 0.0 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 ORX79167.1 - 0.0021 18.5 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain FYDLN_acid PF09538.10 ORX79167.1 - 0.041 14.6 1.1 0.13 13.0 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PMAIP1 PF15150.6 ORX79167.1 - 0.14 12.0 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced Ribosomal_L27 PF01016.19 ORX79168.1 - 2.2e-37 126.9 0.4 3e-37 126.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein C2 PF00168.30 ORX79169.1 - 8.6e-93 305.4 9.8 1.2e-21 76.9 0.0 6.2 6 1 0 6 6 6 5 C2 domain CC2D2AN-C2 PF15625.6 ORX79169.1 - 0.025 14.3 0.5 17 5.1 0.2 3.3 3 0 0 3 3 3 0 CC2D2A N-terminal C2 domain NT-C2 PF10358.9 ORX79169.1 - 0.079 12.7 3.2 8.4 6.1 0.0 3.6 4 0 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins VID27_PH PF17747.1 ORX79169.1 - 0.45 10.8 2.2 16 5.8 0.1 3.7 4 0 0 4 4 4 0 VID27 PH-like domain CAP PF00188.26 ORX79195.1 - 1.3e-14 55.1 0.1 1.8e-14 54.6 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Viral_Hsp90 PF03225.14 ORX79195.1 - 0.2 10.1 0.0 0.24 9.9 0.0 1.0 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue E1-E2_ATPase PF00122.20 ORX79197.1 - 3.1e-47 160.4 0.5 3.1e-47 160.4 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 ORX79197.1 - 1e-40 138.0 7.5 1.3e-13 51.1 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 ORX79197.1 - 3.3e-29 102.7 0.2 1.8e-28 100.3 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_18 PF00704.28 ORX79197.1 - 4.7e-05 23.3 1.4 0.14 11.8 0.0 3.8 2 1 1 4 4 4 1 Glycosyl hydrolases family 18 WAK PF08488.11 ORX79197.1 - 0.0011 19.5 0.7 8.7 6.9 0.1 3.5 1 1 2 3 3 3 1 Wall-associated kinase Hydrolase_3 PF08282.12 ORX79197.1 - 0.0019 18.0 2.3 0.3 10.8 0.1 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX79197.1 - 0.0023 18.3 0.0 0.0066 16.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3071 PF11268.8 ORX79197.1 - 0.048 13.7 0.1 28 4.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3071) Hydrolase_6 PF13344.6 ORX79197.1 - 0.065 13.4 0.0 7.7 6.7 0.0 3.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 ORX79197.1 - 0.097 13.2 0.1 0.87 10.1 0.1 2.5 2 0 0 2 2 2 0 CoA binding domain DUF150 PF02576.17 ORX79197.1 - 0.11 13.0 0.1 56 4.2 0.0 3.8 3 1 1 4 4 4 0 RimP N-terminal domain DUF2774 PF11242.8 ORX79197.1 - 0.21 11.8 0.1 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) DUF1461 PF07314.11 ORX79197.1 - 1.3 8.9 3.7 5.4 6.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1461) Fer4_18 PF13746.6 ORX79197.1 - 3.3 7.9 6.3 60 3.9 0.1 3.8 4 0 0 4 4 4 0 4Fe-4S dicluster domain Apolipoprotein PF01442.18 ORX79198.1 - 2.5e-07 30.7 18.3 0.0018 18.2 11.9 2.4 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain ApoL PF05461.11 ORX79198.1 - 0.00054 19.4 8.6 0.67 9.2 0.2 4.4 2 1 1 4 4 4 2 Apolipoprotein L HisKA_3 PF07730.13 ORX79198.1 - 0.1 13.1 6.0 81 3.8 0.0 5.8 4 1 2 6 6 6 0 Histidine kinase BLM10_mid PF16507.5 ORX79198.1 - 0.11 11.1 0.2 4.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region FPRL1_inhibitor PF16104.5 ORX79198.1 - 0.17 12.0 11.9 0.7 10.1 0.3 3.9 3 1 1 4 4 4 0 Formyl peptide receptor-like 1 inhibitory protein PLAC9 PF15205.6 ORX79198.1 - 0.23 11.9 1.6 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 Placenta-specific protein 9 DUF883 PF05957.13 ORX79198.1 - 0.53 10.9 15.9 19 5.9 2.0 5.0 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) AKNA PF12443.8 ORX79198.1 - 2.5 8.8 14.2 0.12 13.1 1.6 3.7 3 1 1 4 4 3 0 AT-hook-containing transcription factor Telomere_reg-2 PF10193.9 ORX79198.1 - 6 7.4 6.1 29 5.1 0.1 3.6 4 0 0 4 4 4 0 Telomere length regulation protein Laminin_II PF06009.12 ORX79198.1 - 7.4 6.6 28.2 0.82 9.7 0.8 4.7 4 1 0 4 4 4 0 Laminin Domain II WXG100 PF06013.12 ORX79198.1 - 9.7 6.5 14.3 12 6.3 0.0 5.2 4 1 3 7 7 7 0 Proteins of 100 residues with WXG Kp4 PF09044.10 ORX79199.1 - 5e-30 104.1 4.2 5.6e-30 104.0 4.2 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORX79199.1 - 0.064 14.1 5.5 0.78 10.6 5.5 2.1 1 1 0 1 1 1 0 Meiotically up-regulated gene family Kp4 PF09044.10 ORX79200.1 - 6e-30 103.9 4.3 6.7e-30 103.7 4.3 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORX79200.1 - 0.069 14.0 5.9 0.79 10.6 5.9 2.1 1 1 0 1 1 1 0 Meiotically up-regulated gene family Kp4 PF09044.10 ORX79201.1 - 5e-30 104.1 4.2 5.6e-30 104.0 4.2 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORX79201.1 - 0.064 14.1 5.5 0.78 10.6 5.5 2.1 1 1 0 1 1 1 0 Meiotically up-regulated gene family Kp4 PF09044.10 ORX79202.1 - 3.4e-30 104.7 4.0 4.5e-30 104.3 4.0 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORX79202.1 - 0.16 12.8 5.6 1.9 9.3 5.6 2.1 1 1 0 1 1 1 0 Meiotically up-regulated gene family Kp4 PF09044.10 ORX79203.1 - 2.3e-30 105.2 4.0 2.8e-30 105.0 4.0 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORX79203.1 - 0.097 13.5 5.5 1.2 10.0 5.5 2.1 1 1 0 1 1 1 0 Meiotically up-regulated gene family Xan_ur_permease PF00860.20 ORX79246.1 - 2.3e-63 214.3 35.5 4.8e-62 209.9 35.5 2.1 1 1 0 1 1 1 1 Permease family bZIP_2 PF07716.15 ORX79247.1 - 2.7e-06 27.3 11.3 6e-06 26.2 11.0 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX79247.1 - 0.4 10.8 12.7 0.73 10.0 11.8 1.9 1 1 0 1 1 1 0 bZIP transcription factor YlqD PF11068.8 ORX79247.1 - 1.1 9.7 7.0 2.4 8.6 2.1 2.1 1 1 1 2 2 2 0 YlqD protein Asparaginase_2 PF01112.18 ORX79249.1 - 2.8e-44 151.4 0.4 6.6e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Asparaginase DUF5009 PF16401.5 ORX79250.1 - 2.6e-06 27.1 4.9 2.6e-06 27.1 4.9 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) GWT1 PF06423.12 ORX79250.1 - 0.0056 16.8 3.9 0.0056 16.8 3.9 2.8 3 0 0 3 3 3 2 GWT1 C2-C2_1 PF11618.8 ORX79251.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 Hydrolase_4 PF12146.8 ORX79275.1 - 0.045 13.0 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Mt_ATP-synt_D PF05873.12 ORX79276.1 - 2e-20 73.2 4.0 2.4e-20 72.9 4.0 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HALZ PF02183.18 ORX79276.1 - 0.02 15.1 1.4 0.13 12.5 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 ORX79276.1 - 0.021 14.8 1.5 0.64 10.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pet20 PF08692.10 ORX79276.1 - 0.024 15.4 0.1 0.052 14.3 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial protein Pet20 ZapB PF06005.12 ORX79276.1 - 0.052 14.0 1.6 0.86 10.1 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF4618 PF15397.6 ORX79276.1 - 0.053 12.9 4.0 0.07 12.5 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2408 PF10303.9 ORX79276.1 - 0.071 13.7 2.3 0.31 11.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) CdvA PF18822.1 ORX79276.1 - 0.19 11.6 4.2 1.1 9.2 0.6 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain BST2 PF16716.5 ORX79276.1 - 0.25 11.9 3.2 0.68 10.6 0.6 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Spc24 PF08286.11 ORX79276.1 - 0.29 11.4 4.2 3.3 8.0 0.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 ORX79276.1 - 0.46 10.7 6.9 0.96 9.7 0.9 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 ORX79276.1 - 0.5 10.2 4.1 8.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator MscS_porin PF12795.7 ORX79276.1 - 1.2 8.6 7.2 2.1 7.9 1.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 ORX79276.1 - 2 8.5 7.6 8.2 6.5 0.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tetraspanin PF00335.20 ORX79277.1 - 2.6e-06 27.3 21.5 1.1e-05 25.3 21.9 1.8 1 1 0 1 1 1 1 Tetraspanin family Sugar_tr PF00083.24 ORX79278.1 - 5.4e-129 431.0 19.1 1.3e-128 429.7 19.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX79278.1 - 6.7e-21 74.6 44.5 6e-11 41.9 18.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Lactamase_B PF00753.27 ORX79279.1 - 3.9e-15 56.4 0.4 1e-07 32.1 0.0 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily TPR_2 PF07719.17 ORX79279.1 - 7.3e-06 25.7 3.3 0.27 11.4 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 ORX79279.1 - 1.2e-05 25.4 0.3 5.2e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 ORX79279.1 - 0.031 14.1 3.2 4.8 7.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 ORX79279.1 - 0.032 13.7 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HTH_50 PF18024.1 ORX79279.1 - 0.11 12.1 0.1 14 5.4 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain RabGAP-TBC PF00566.18 ORX79280.1 - 2e-38 132.2 0.6 2.7e-38 131.8 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ER_lumen_recept PF00810.18 ORX79280.1 - 0.11 13.3 2.0 0.13 13.1 1.0 1.6 1 1 1 2 2 2 0 ER lumen protein retaining receptor FAD_binding_8 PF08022.12 ORX79281.1 - 7e-21 74.4 0.0 1.2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ORX79281.1 - 4.2e-20 72.1 14.1 4.2e-20 72.1 14.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORX79281.1 - 9e-09 35.6 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Peptidase_M16_C PF05193.21 ORX79313.1 - 2.4e-45 154.8 0.0 4.4e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORX79313.1 - 8.9e-45 152.3 0.0 2.6e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Lon_C PF05362.13 ORX79314.1 - 1.8e-69 233.4 0.0 3.7e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORX79314.1 - 8.5e-35 120.5 0.0 2.3e-34 119.1 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORX79314.1 - 1.4e-22 80.6 0.0 3.5e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 ORX79314.1 - 3.9e-07 29.9 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 ORX79314.1 - 5.8e-07 29.6 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORX79314.1 - 2.7e-06 27.6 0.0 6.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORX79314.1 - 5.5e-05 23.7 0.3 0.00083 19.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 ORX79314.1 - 9.1e-05 21.5 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ORX79314.1 - 0.00011 22.0 0.0 0.00043 20.1 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX79314.1 - 0.0003 21.1 0.1 0.0028 17.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX79314.1 - 0.0011 19.4 0.6 0.0075 16.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 ORX79314.1 - 0.005 16.8 0.5 0.23 11.4 0.0 3.1 2 1 1 3 3 3 1 NTPase AAA_14 PF13173.6 ORX79314.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORX79314.1 - 0.035 13.3 0.1 0.075 12.2 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 ORX79314.1 - 0.04 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 ORX79314.1 - 0.042 14.0 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase AAA_30 PF13604.6 ORX79314.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORX79314.1 - 0.052 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 ORX79314.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORX79314.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 ORX79314.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 ORX79314.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PSK_trans_fac PF07704.11 ORX79314.1 - 0.14 12.9 0.3 39 5.1 0.0 3.1 2 0 0 2 2 2 0 Rv0623-like transcription factor TauD PF02668.16 ORX79315.1 - 1.5e-07 31.5 0.1 1.8e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Response_reg PF00072.24 ORX79347.1 - 9.7e-53 177.1 0.1 1.4e-25 89.6 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX79347.1 - 2.2e-48 163.4 1.0 1.2e-22 80.5 0.3 3.4 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX79347.1 - 6.8e-23 80.5 1.8 4.9e-14 52.1 0.2 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX79347.1 - 6.9e-12 45.5 0.4 3.6e-10 40.0 0.2 2.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ORX79347.1 - 1e-11 45.1 0.0 0.00027 21.1 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 ORX79347.1 - 7.1e-11 42.1 0.3 2.7e-08 33.8 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ORX79347.1 - 2.2e-08 34.3 0.2 4.7e-05 23.6 0.0 4.3 4 0 0 4 4 3 1 PAS domain HATPase_c_3 PF13589.6 ORX79347.1 - 3.9e-06 26.7 0.2 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 ORX79347.1 - 0.0039 17.5 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ORX79347.1 - 0.0049 17.2 0.0 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 ORX79347.1 - 0.0082 16.1 0.0 5.6 7.1 0.0 3.5 3 0 0 3 3 3 1 PAS domain Response_reg PF00072.24 ORX79348.1 - 5.4e-52 174.7 0.2 8.8e-25 87.1 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX79348.1 - 7.2e-45 152.1 2.5 8.6e-21 74.5 0.2 3.5 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX79348.1 - 6.4e-23 80.6 0.7 1.1e-13 51.0 0.0 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX79348.1 - 1.1e-06 28.9 1.0 2.9e-06 27.5 0.4 2.1 2 0 0 2 2 1 1 PAS fold HATPase_c_3 PF13589.6 ORX79348.1 - 1.3e-06 28.3 0.1 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ORX79348.1 - 6e-05 23.0 0.1 0.00064 19.7 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ORX79348.1 - 0.0012 18.8 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX79348.1 - 0.0016 18.7 0.0 0.29 11.4 0.0 3.0 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 ORX79348.1 - 0.0025 18.1 0.0 0.025 14.9 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_9 PF13426.7 ORX79348.1 - 0.008 16.4 0.0 0.45 10.8 0.0 3.4 3 0 0 3 3 3 1 PAS domain GAF_3 PF13492.6 ORX79348.1 - 0.02 15.2 0.0 0.084 13.2 0.0 2.0 2 0 0 2 2 2 0 GAF domain Prefoldin_2 PF01920.20 ORX79348.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.2 3 0 0 3 3 2 0 Prefoldin subunit Response_reg PF00072.24 ORX79349.1 - 1.1e-52 176.9 0.1 1.4e-25 89.6 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX79349.1 - 4.3e-47 159.2 4.0 2.1e-22 79.7 0.3 3.6 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX79349.1 - 3.6e-21 75.0 0.8 3.8e-14 52.5 0.3 3.3 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX79349.1 - 4.1e-11 43.0 0.3 1.8e-10 41.0 0.3 2.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ORX79349.1 - 1.2e-09 38.4 0.0 0.00069 19.8 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORX79349.1 - 1.4e-08 34.7 0.6 8.5e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ORX79349.1 - 1.3e-06 28.6 1.1 0.00028 21.1 0.0 4.5 5 0 0 5 5 5 1 PAS domain HATPase_c_3 PF13589.6 ORX79349.1 - 1.5e-06 28.1 0.2 0.015 15.2 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ORX79349.1 - 3.1e-05 23.9 0.0 0.0049 16.9 0.0 3.4 3 0 0 3 3 3 1 PAS domain GAF_3 PF13492.6 ORX79349.1 - 0.032 14.6 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain GAF_2 PF13185.6 ORX79349.1 - 0.13 12.5 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 GAF domain Response_reg PF00072.24 ORX79350.1 - 1.6e-53 179.6 0.3 3.3e-25 88.4 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX79350.1 - 2.3e-49 166.5 0.9 8.5e-24 84.2 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX79350.1 - 8.5e-23 80.2 1.6 1.1e-13 51.0 0.1 3.2 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORX79350.1 - 1.2e-08 35.1 0.0 0.012 15.9 0.0 3.2 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX79350.1 - 3.8e-07 30.3 0.5 1.9e-06 28.1 0.5 2.3 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ORX79350.1 - 9.2e-07 28.8 0.2 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ORX79350.1 - 0.00023 21.1 0.0 0.0007 19.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORX79350.1 - 0.0011 19.2 0.0 0.024 14.9 0.0 3.3 3 0 0 3 3 3 1 PAS domain GAF_3 PF13492.6 ORX79350.1 - 0.025 14.9 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 GAF domain GAF_2 PF13185.6 ORX79350.1 - 0.093 13.0 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 GAF domain PAS_8 PF13188.7 ORX79350.1 - 0.15 12.1 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 PAS domain Peptidase_S9 PF00326.21 ORX79351.1 - 3.5e-57 193.3 0.7 6.6e-57 192.4 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORX79351.1 - 7.2e-09 35.4 10.0 0.083 12.9 0.0 5.3 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 ORX79351.1 - 2.5e-05 24.0 0.6 0.089 12.4 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORX79351.1 - 0.00041 19.1 0.1 0.0048 15.6 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ORX79351.1 - 0.015 14.9 0.0 0.039 13.5 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family SGL PF08450.12 ORX79351.1 - 0.03 13.9 0.2 9.4 5.7 0.0 3.1 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region DUF2920 PF11144.8 ORX79351.1 - 0.042 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 ORX79351.1 - 0.1 11.8 0.0 7.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3472 PF11958.8 ORX79399.1 - 2.5e-11 44.4 0.0 4.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX79399.1 - 1.6e-05 24.9 0.1 3.8e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF1461 PF07314.11 ORX79399.1 - 0.15 11.9 1.5 0.31 10.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Peripla_BP_2 PF01497.18 ORX79400.1 - 0.067 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_1 PF00561.20 ORX79401.1 - 2.4e-10 40.5 0.0 2.9e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX79401.1 - 4.9e-09 35.8 0.0 5.9e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX79401.1 - 0.00028 21.6 0.1 0.00031 21.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family LytR_C PF13399.6 ORX79401.1 - 0.063 14.3 0.1 0.1 13.6 0.1 1.5 1 1 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator GPI-anchored PF10342.9 ORX79402.1 - 0.0021 18.7 0.1 0.0055 17.4 0.1 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Imm21 PF15589.6 ORX79402.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 21 CK_II_beta PF01214.18 ORX79426.1 - 2.1e-79 265.5 0.1 2.9e-79 265.1 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Tubulin PF00091.25 ORX79427.1 - 2.1e-66 223.9 0.0 3.2e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX79427.1 - 1.6e-51 173.7 0.1 2.7e-51 173.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORX79427.1 - 0.00037 20.2 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain zf-RING_11 PF17123.5 ORX79428.1 - 4.9e-08 32.6 1.5 1.1e-07 31.4 1.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORX79428.1 - 1.5e-05 25.3 1.1 2.7e-05 24.4 1.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX79428.1 - 0.00074 19.3 2.1 0.0014 18.5 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX79428.1 - 0.0021 17.9 1.1 0.0044 16.8 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX79428.1 - 0.0086 16.1 2.3 0.018 15.1 2.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX79428.1 - 0.059 13.3 0.9 0.1 12.5 0.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_M14 PF00246.24 ORX79429.1 - 5.4e-67 226.6 0.0 9.6e-61 206.1 0.0 2.2 1 1 1 2 2 2 2 Zinc carboxypeptidase Propep_M14 PF02244.16 ORX79429.1 - 0.0065 16.8 0.3 0.019 15.3 0.3 1.8 1 1 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.14 ORX79429.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Arf PF00025.21 ORX79430.1 - 9.1e-80 266.2 0.1 1e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX79430.1 - 1.5e-14 53.8 0.0 1.8e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORX79430.1 - 2.5e-14 53.5 0.0 3.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORX79430.1 - 2.3e-13 50.1 1.1 1.9e-09 37.2 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORX79430.1 - 5.1e-13 48.9 0.0 5.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX79430.1 - 1e-10 41.4 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX79430.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX79430.1 - 0.0073 15.6 0.5 0.018 14.4 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase IPK PF03770.16 ORX79433.1 - 4.6e-49 167.0 0.0 7.1e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase HABP4_PAI-RBP1 PF04774.15 ORX79458.1 - 2e-06 28.6 0.9 2.7e-06 28.2 0.5 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Glyco_hydro_61 PF03443.14 ORX79459.1 - 0.00081 19.4 0.5 0.0014 18.6 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 ORX79460.1 - 0.00094 19.2 0.2 0.0017 18.4 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX79460.1 - 0.02 15.6 6.2 0.06 14.0 6.2 2.1 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 ORX79461.1 - 0.0032 18.2 3.1 0.0032 18.2 3.1 2.2 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DNA_pol_phi PF04931.13 ORX79461.1 - 0.035 12.2 18.1 0.047 11.8 18.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Tub_N PF16322.5 ORX79461.1 - 0.17 12.3 4.6 0.32 11.4 4.6 1.3 1 0 0 1 1 1 0 Tubby N-terminal DUF2722 PF10846.8 ORX79461.1 - 0.18 10.7 4.7 0.24 10.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Cwf_Cwc_15 PF04889.12 ORX79461.1 - 0.19 11.4 14.6 0.3 10.8 14.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 ORX79461.1 - 0.32 9.5 6.1 0.42 9.1 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 ORX79461.1 - 0.44 9.9 11.5 0.63 9.4 11.5 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 ORX79461.1 - 0.51 10.1 6.8 0.87 9.4 6.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 ORX79461.1 - 0.52 8.5 13.7 0.68 8.1 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 ORX79461.1 - 1.2 8.4 18.0 2.4 7.4 18.0 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 ORX79461.1 - 3 7.7 8.4 4.4 7.1 8.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region IFT57 PF10498.9 ORX79461.1 - 7.4 5.4 6.0 10 4.9 6.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 LPMO_10 PF03067.15 ORX79462.1 - 0.0024 18.6 3.1 0.0024 18.6 3.1 1.9 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF2722 PF10846.8 ORX79462.1 - 0.28 10.1 12.0 0.36 9.7 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 ORX79462.1 - 1.3 7.1 29.4 1.6 6.8 29.4 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 ORX79462.1 - 8.5 5.0 10.1 10 4.8 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_hydro_61 PF03443.14 ORX79463.1 - 0.00099 19.1 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX79463.1 - 0.038 14.7 3.4 0.072 13.7 3.4 1.5 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading TSP_3 PF02412.18 ORX79464.1 - 0.0012 18.5 18.5 0.5 10.1 1.0 3.5 2 1 1 3 3 3 3 Thrombospondin type 3 repeat Excalibur PF05901.11 ORX79464.1 - 0.0013 19.3 10.9 0.83 10.3 1.2 3.4 3 0 0 3 3 3 3 Excalibur calcium-binding domain Sorb PF02208.16 ORX79464.1 - 0.047 13.6 0.4 3.8 7.5 0.0 2.8 2 1 1 3 3 3 0 Sorbin homologous domain Binary_toxB PF03495.14 ORX79464.1 - 0.27 11.5 13.1 7.2 6.9 0.3 3.2 3 0 0 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DUF3446 PF11928.8 ORX79465.1 - 0.33 11.3 14.3 0.047 14.0 10.0 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Peptidase_C78 PF07910.13 ORX79517.1 - 3.5e-60 203.1 0.0 4.8e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Chs7 PF12271.8 ORX79518.1 - 8.2e-107 356.8 22.4 9.3e-107 356.7 22.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Connexin PF00029.19 ORX79518.1 - 1.3 8.7 5.5 0.39 10.4 0.5 2.3 2 1 0 2 2 2 0 Connexin DUF2070 PF09843.9 ORX79518.1 - 2.5 6.3 26.5 0.46 8.7 23.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) RRM_1 PF00076.22 ORX79519.1 - 1.5e-58 194.5 0.0 1.2e-20 73.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX79519.1 - 8.1e-10 38.4 0.0 0.00018 21.1 0.0 3.2 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX79519.1 - 1.9e-07 30.8 0.0 0.00019 21.2 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX79519.1 - 0.0035 17.4 0.1 0.31 11.2 0.0 3.6 4 1 0 4 4 4 1 RNA recognition motif SET_assoc PF11767.8 ORX79519.1 - 0.012 15.2 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 ORX79519.1 - 0.053 13.5 0.3 39 4.4 0.1 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Arm PF00514.23 ORX79521.1 - 1.1e-71 234.9 26.7 2e-12 46.7 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORX79521.1 - 1.2e-19 70.4 9.8 0.005 17.3 0.1 8.6 6 3 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 ORX79521.1 - 9.5e-19 67.6 12.6 0.005 17.2 0.0 7.8 2 2 6 8 8 8 6 HEAT repeats HEAT PF02985.22 ORX79521.1 - 1.1e-16 59.5 12.8 0.16 12.3 0.0 9.7 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.20 ORX79521.1 - 6.9e-14 51.3 15.4 3.1e-08 32.6 1.9 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 ORX79521.1 - 8.9e-12 44.0 1.7 1.4e-11 43.4 1.7 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 ORX79521.1 - 1.3e-08 34.6 4.5 0.00079 18.8 0.3 3.5 1 1 2 3 3 3 3 V-ATPase subunit H Arm_2 PF04826.13 ORX79521.1 - 1.8e-08 34.2 10.3 1.5e-05 24.6 5.1 2.7 1 1 0 2 2 2 2 Armadillo-like Cnd1 PF12717.7 ORX79521.1 - 1.3e-07 31.8 7.9 0.14 12.2 0.8 4.7 2 2 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORX79521.1 - 0.00027 21.5 0.3 0.75 10.4 0.0 4.0 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 ORX79521.1 - 0.0011 19.0 11.6 0.06 13.3 0.2 4.4 1 1 2 4 4 4 1 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 ORX79521.1 - 0.0014 19.1 8.1 3.3 8.7 0.2 6.7 8 0 0 8 8 6 1 PBS lyase HEAT-like repeat IFRD PF05004.13 ORX79521.1 - 0.0015 17.7 8.2 0.39 9.8 0.1 4.7 3 3 2 5 5 5 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 ORX79521.1 - 0.0035 17.5 1.0 0.64 10.2 0.0 3.9 2 1 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 ORX79521.1 - 0.0083 16.2 8.7 21 5.2 0.1 6.0 4 2 5 9 9 8 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 ORX79521.1 - 0.96 9.5 6.0 3.6 7.7 0.5 4.2 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain EF-hand_4 PF12763.7 ORX79522.1 - 6.6e-31 106.3 0.0 6.7e-16 58.1 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORX79522.1 - 1.3e-09 36.9 0.0 0.17 11.5 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 ORX79522.1 - 7.1e-08 32.8 0.3 0.00037 20.9 0.0 3.1 2 1 1 3 3 2 2 EF-hand domain pair UBA PF00627.31 ORX79522.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 ORX79522.1 - 9.9e-05 22.0 0.0 1.5 9.0 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 ORX79522.1 - 0.00081 19.2 0.0 4.9 7.1 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain pair UBA_4 PF14555.6 ORX79522.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain HAUS-augmin3 PF14932.6 ORX79522.1 - 0.24 11.0 14.0 0.49 9.9 14.0 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PRKG1_interact PF15898.5 ORX79522.1 - 0.24 12.3 21.0 0.11 13.3 17.0 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 ORX79522.1 - 0.26 8.8 19.4 0.34 8.4 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 ORX79522.1 - 0.32 9.8 24.0 0.59 9.0 24.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 ORX79522.1 - 0.32 10.0 18.5 0.6 9.1 18.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 ORX79522.1 - 0.83 10.2 30.3 24 5.5 30.3 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Tho2 PF11262.8 ORX79522.1 - 1.4 8.1 10.0 2.3 7.4 10.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AAA_23 PF13476.6 ORX79522.1 - 1.6 9.2 17.7 3.8 8.0 17.7 1.7 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 ORX79522.1 - 1.9 8.9 21.7 2.8 8.4 21.0 1.5 1 1 0 1 1 1 0 Fez1 FAM76 PF16046.5 ORX79522.1 - 3.7 6.8 13.0 6.5 6.0 13.0 1.3 1 0 0 1 1 1 0 FAM76 protein Tup_N PF08581.10 ORX79522.1 - 3.7 7.9 19.9 23 5.4 15.5 2.5 2 0 0 2 2 2 0 Tup N-terminal Seryl_tRNA_N PF02403.22 ORX79522.1 - 3.8 7.8 20.7 3.2 8.0 15.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 ORX79522.1 - 4.8 6.4 12.4 9.1 5.5 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PCRF PF03462.18 ORX79522.1 - 10 6.0 10.7 20 5.0 10.7 1.5 1 0 0 1 1 1 0 PCRF domain DUF4179 PF13786.6 ORX79547.1 - 0.17 12.4 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GRP PF07172.11 ORX79549.1 - 0.086 13.5 13.8 0.1 13.3 12.8 1.7 2 0 0 2 2 2 0 Glycine rich protein family Sod_Ni PF09055.11 ORX79549.1 - 0.19 12.3 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase GRP PF07172.11 ORX79553.1 - 3.7 8.3 24.0 5.9 7.6 24.0 1.5 1 1 0 1 1 1 0 Glycine rich protein family PHO4 PF01384.20 ORX79583.1 - 5.7e-103 344.5 11.2 7.2e-103 344.2 11.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF2834 PF11196.8 ORX79583.1 - 6.2 7.3 8.9 4.9 7.6 0.8 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) Cyclin_N PF00134.23 ORX79610.1 - 2.1e-22 79.2 0.6 2.1e-18 66.3 0.5 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORX79610.1 - 0.00012 22.0 0.1 0.55 10.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORX79610.1 - 0.0002 21.4 0.0 0.00082 19.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 ORX79610.1 - 0.00084 19.7 0.2 0.0048 17.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin C-terminal domain Glyco_hydro_17 PF00332.18 ORX79612.1 - 1e-10 41.8 0.8 3.6e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 PhoD PF09423.10 ORX79614.1 - 1.6e-05 24.1 0.0 0.0002 20.5 0.0 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase MMR_HSR1 PF01926.23 ORX79615.1 - 2.5e-09 37.2 0.0 5.4e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX79615.1 - 0.00016 21.6 0.0 0.0007 19.5 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORX79615.1 - 0.012 15.9 0.2 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 ORX79615.1 - 0.023 14.2 0.1 0.69 9.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORX79615.1 - 0.07 12.7 0.2 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 ORX79615.1 - 0.11 12.1 0.2 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Ras family TPR_12 PF13424.6 ORX79616.1 - 5.1e-17 61.9 4.4 1.5e-06 28.4 0.7 4.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORX79616.1 - 2.5e-14 52.1 14.8 0.0014 18.6 0.1 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORX79616.1 - 4.4e-12 45.2 9.8 0.019 15.2 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX79616.1 - 9.5e-12 44.2 15.1 0.066 13.1 0.1 6.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORX79616.1 - 1.5e-09 37.2 8.2 0.007 16.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX79616.1 - 1.1e-06 28.2 0.3 0.00054 19.4 0.0 2.3 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 ORX79616.1 - 3.4e-06 26.7 9.3 0.19 11.7 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX79616.1 - 6.9e-05 23.3 5.7 0.28 12.1 0.7 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX79616.1 - 9.9e-05 22.8 3.0 0.0021 18.5 0.1 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 ORX79616.1 - 0.00048 19.7 0.3 0.28 10.6 0.0 3.2 2 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like DUF2225 PF09986.9 ORX79616.1 - 0.0069 16.1 2.6 0.053 13.2 0.1 2.7 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Rapsyn_N PF10579.9 ORX79616.1 - 0.0071 16.4 0.3 0.064 13.4 0.0 2.6 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.6 ORX79616.1 - 0.0083 16.8 5.2 0.047 14.4 0.6 4.0 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 ORX79616.1 - 0.023 14.8 0.1 0.13 12.4 0.0 2.3 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.12 ORX79616.1 - 0.026 14.5 0.1 0.95 9.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 ORX79616.1 - 0.036 14.3 2.7 41 4.5 0.0 3.9 2 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORX79616.1 - 0.037 14.7 3.1 2 9.2 0.1 4.4 6 0 0 6 6 4 0 Tetratricopeptide repeat APG6_N PF17675.1 ORX79616.1 - 0.05 14.1 1.3 0.05 14.1 1.3 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region GST_C_6 PF17171.4 ORX79616.1 - 0.09 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_C48 PF02902.19 ORX79617.1 - 8.8e-46 156.5 0.1 1.2e-45 156.0 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 ORX79617.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain bZIP_2 PF07716.15 ORX79618.1 - 2.3e-11 43.6 6.6 2.3e-11 43.6 6.6 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX79618.1 - 3.9e-08 33.3 8.3 7.1e-08 32.4 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX79618.1 - 4e-05 24.1 6.2 8.2e-05 23.0 6.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor HMMR_N PF15905.5 ORX79618.1 - 0.014 14.9 12.7 0.019 14.5 12.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 ORX79618.1 - 0.017 15.7 5.5 0.023 15.3 5.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 ORX79618.1 - 0.028 14.3 0.8 0.86 9.6 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CLZ PF16526.5 ORX79618.1 - 0.41 11.0 6.7 0.38 11.1 5.5 1.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 ORX79618.1 - 0.69 10.2 5.3 1.6 9.0 5.1 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain ZapB PF06005.12 ORX79618.1 - 1.3 9.5 9.7 1.2 9.6 8.6 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Membralin PF09746.9 ORX79618.1 - 1.7 7.6 4.9 2.2 7.3 4.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein NAM-associated PF14303.6 ORX79618.1 - 2.9 8.6 13.0 4.4 8.0 13.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain LIM PF00412.22 ORX79619.1 - 7.4e-26 90.2 61.9 9.5e-10 38.6 1.6 5.8 6 0 0 6 6 6 4 LIM domain Peptidase_S8 PF00082.22 ORX79620.1 - 8.5e-25 87.6 7.2 2.8e-24 85.9 7.2 1.7 1 1 0 1 1 1 1 Subtilase family Fungal_trans PF04082.18 ORX79621.1 - 3.9e-39 134.3 1.3 7.2e-39 133.4 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RhoGEF PF00621.20 ORX79644.1 - 9.9e-26 91.1 0.1 2.5e-25 89.8 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 ORX79644.1 - 2.2e-22 79.0 21.9 5.1e-17 61.8 7.5 2.5 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 ORX79644.1 - 2.2e-06 27.9 13.7 0.0027 17.9 3.1 2.9 2 0 0 2 2 2 2 FYVE-type zinc finger PH PF00169.29 ORX79644.1 - 3.2e-06 27.6 0.2 1.2e-05 25.8 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 ORX79644.1 - 0.0013 18.5 0.4 0.019 14.8 0.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain SinI PF08671.10 ORX79644.1 - 2.4 8.0 5.0 18 5.2 0.1 3.1 3 0 0 3 3 3 0 Anti-repressor SinI RhoGEF PF00621.20 ORX79645.1 - 5.3e-46 157.1 2.7 1.1e-45 156.1 2.7 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 ORX79645.1 - 1.2e-22 79.8 27.2 2.3e-17 62.9 9.7 2.9 3 0 0 3 3 3 2 FYVE zinc finger PH PF00169.29 ORX79645.1 - 1.7e-07 31.7 1.1 5.2e-07 30.1 0.1 2.3 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 ORX79645.1 - 0.0025 17.6 0.4 0.023 14.5 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.16 ORX79645.1 - 0.0042 17.3 5.1 0.0042 17.3 5.1 2.9 2 1 0 2 2 2 2 FYVE-type zinc finger 2Fe-2S_thioredx PF01257.19 ORX79645.1 - 0.34 10.8 1.6 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin Siva PF05458.12 ORX79645.1 - 6.4 6.4 11.2 0.47 10.1 1.5 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Ribosomal_S17_N PF16205.5 ORX79646.1 - 2.8e-33 114.1 0.4 6.2e-33 113.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORX79646.1 - 2.4e-27 94.8 0.4 3.6e-27 94.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 NUDIX PF00293.28 ORX79647.1 - 1.4e-16 60.7 0.0 2.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 ORX79647.1 - 1e-09 38.9 0.0 3.1e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ORX79647.1 - 8.1e-07 28.6 0.1 1.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DpnI PF06044.12 ORX79647.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Dam-replacing family MFS_MOT1 PF16983.5 ORX79648.1 - 2.5e-58 195.3 28.9 1.1e-31 109.5 7.6 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 ORX79648.1 - 3.7e-06 25.9 20.4 3.3e-05 22.8 20.4 2.3 1 1 0 1 1 1 1 Sulfate permease family DUF2569 PF10754.9 ORX79648.1 - 0.32 11.4 7.1 0.09 13.2 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) TPPK_C PF12555.8 ORX79648.1 - 0.39 10.8 3.2 0.52 10.4 0.3 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MFS_MOT1 PF16983.5 ORX79649.1 - 2.6e-58 195.2 28.9 1.1e-31 109.5 7.6 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 ORX79649.1 - 6.1e-06 25.2 21.2 5e-05 22.2 21.2 2.3 1 1 0 1 1 1 1 Sulfate permease family DUF2569 PF10754.9 ORX79649.1 - 0.56 10.6 7.5 0.1 13.0 1.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) TPPK_C PF12555.8 ORX79649.1 - 1.1 9.3 4.0 0.99 9.5 0.6 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal WD40 PF00400.32 ORX79674.1 - 1e-19 70.5 3.9 0.00053 20.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX79674.1 - 4.4e-08 33.3 0.0 0.37 11.1 0.0 4.4 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain GspH PF12019.8 ORX79674.1 - 0.012 16.0 0.3 0.34 11.3 0.0 2.8 2 1 1 3 3 3 0 Type II transport protein GspH SE PF08491.10 ORX79696.1 - 9.9e-12 44.5 0.0 3e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Squalene epoxidase IBN_N PF03810.19 ORX79697.1 - 9.6e-14 51.1 0.8 2e-12 46.9 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 ORX79697.1 - 1.6e-11 43.7 0.1 4.4e-11 42.2 0.1 1.8 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 ORX79697.1 - 8.7e-06 25.9 1.4 0.00018 21.6 0.1 3.4 2 0 0 2 2 2 1 Exportin 1-like protein RIX1 PF08167.12 ORX79697.1 - 0.0013 18.5 5.7 0.0026 17.5 0.0 3.4 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis MOR2-PAG1_C PF14225.6 ORX79697.1 - 0.07 13.0 1.8 2.3 8.0 0.1 3.4 3 1 0 3 3 3 0 Cell morphogenesis C-terminal HEAT_EZ PF13513.6 ORX79697.1 - 0.34 11.5 1.2 30 5.3 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat DUF1451 PF07295.11 ORX79697.1 - 8.7 6.4 6.0 2.1 8.3 0.1 2.6 3 0 0 3 3 3 0 Zinc-ribbon containing domain Ctr PF04145.15 ORX79698.1 - 5.2e-31 108.3 3.9 6.1e-31 108.0 3.9 1.0 1 0 0 1 1 1 1 Ctr copper transporter family MFS_MOT1 PF16983.5 ORX79699.1 - 8.7e-60 200.0 28.1 8.4e-33 113.1 7.1 2.7 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 ORX79699.1 - 1.4e-05 24.0 18.9 0.00024 20.0 18.9 2.6 1 1 0 1 1 1 1 Sulfate permease family DEAD PF00270.29 ORX79700.1 - 3.7e-45 153.8 0.0 7.2e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX79700.1 - 5.5e-30 104.0 0.0 1.5e-29 102.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 ORX79700.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 ORX79700.1 - 0.04 13.9 0.0 0.14 12.1 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Kinase-PPPase PF03618.14 ORX79700.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase ERCC3_RAD25_C PF16203.5 ORX79700.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 ORX79700.1 - 0.28 11.5 0.8 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain EI24 PF07264.11 ORX79701.1 - 4.7e-18 66.1 19.1 6.3e-18 65.6 19.1 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Methyltransf_16 PF10294.9 ORX79702.1 - 2.9e-33 115.0 0.3 3.7e-33 114.7 0.3 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORX79702.1 - 2.9e-08 33.4 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORX79702.1 - 0.00024 20.7 0.1 0.00035 20.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORX79702.1 - 0.00063 19.6 0.0 0.00085 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX79702.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX79702.1 - 0.0023 18.6 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX79702.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX79702.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF188 PF02639.14 ORX79702.1 - 0.11 12.2 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Cyclin PF08613.11 ORX79703.1 - 5.3e-14 52.9 0.0 8.2e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX79703.1 - 2.4e-11 43.5 0.0 3.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RGS PF00615.19 ORX79704.1 - 2e-10 41.0 0.0 5.7e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_A8 PF01252.18 ORX79704.1 - 0.98 9.7 9.1 0.18 12.1 0.4 3.0 1 1 0 3 3 3 0 Signal peptidase (SPase) II SRI PF08236.11 ORX79705.1 - 1.9e-18 66.4 4.4 4.3e-18 65.3 4.4 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 ORX79705.1 - 3.5e-18 65.4 6.6 3.5e-18 65.4 6.6 2.6 3 0 0 3 3 3 1 AWS domain SET PF00856.28 ORX79705.1 - 2.9e-17 63.6 1.5 8.3e-17 62.1 0.0 2.6 2 2 0 2 2 2 1 SET domain WW PF00397.26 ORX79705.1 - 3.7e-10 39.7 0.2 8.7e-10 38.5 0.2 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 ORX79705.1 - 7.1e-06 25.9 0.8 3.7e-05 23.6 0.1 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Peptidase_M4_C PF02868.15 ORX79705.1 - 0.046 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Glyco_hyd_101C PF17451.2 ORX79705.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain SNF2_N PF00176.23 ORX79706.1 - 1.7e-74 250.6 0.3 5.3e-74 249.0 0.2 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 ORX79706.1 - 1.2e-42 144.5 1.8 1.2e-42 144.5 1.8 2.6 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 ORX79706.1 - 5.3e-31 107.6 6.6 5.3e-31 107.6 6.6 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 ORX79706.1 - 3.5e-18 66.0 0.0 7.4e-17 61.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX79706.1 - 7.6e-11 42.3 0.1 1.5e-09 38.1 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORX79706.1 - 5.4e-06 26.3 0.0 2.1e-05 24.4 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 ORX79706.1 - 4.7e-05 22.7 0.1 4.7e-05 22.7 0.1 2.7 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 ORX79706.1 - 0.047 13.9 6.6 1.5 9.1 0.2 3.7 3 1 0 3 3 3 0 Myb-like DNA-binding domain ERCC3_RAD25_C PF16203.5 ORX79706.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.7 2 1 1 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 ORX79706.1 - 0.12 12.6 0.9 1.7 8.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain BRO1 PF03097.18 ORX79707.1 - 6.4e-133 443.3 0.6 6.4e-133 443.3 0.6 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORX79707.1 - 3.4e-81 272.8 7.9 3.4e-81 272.8 7.9 2.7 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV DUF1569 PF07606.11 ORX79707.1 - 0.04 13.9 0.9 0.13 12.2 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) ABC_tran_Xtn PF12848.7 ORX79707.1 - 0.14 12.2 5.4 0.09 12.8 1.3 2.7 2 1 0 2 2 2 0 ABC transporter Sec34 PF04136.15 ORX79707.1 - 0.56 10.1 5.3 0.87 9.5 3.5 2.3 2 0 0 2 2 2 0 Sec34-like family An_peroxidase PF03098.15 ORX79734.1 - 3.8e-45 154.5 0.0 4.8e-34 117.8 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase Lipase_3 PF01764.25 ORX79735.1 - 9.7e-22 77.4 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX79735.1 - 0.073 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SHP PF03579.13 ORX79735.1 - 0.14 12.1 5.7 0.4 10.7 5.7 1.7 1 0 0 1 1 1 0 Small hydrophobic protein UPF0542 PF15086.6 ORX79735.1 - 0.23 11.4 4.0 0.86 9.6 2.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 PPC PF04151.15 ORX79736.1 - 0.069 14.3 0.3 0.14 13.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Acetyltransf_1 PF00583.25 ORX79737.1 - 2.3e-06 27.9 0.1 1.6e-05 25.1 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX79737.1 - 4.7e-05 23.7 0.8 9.1e-05 22.8 0.8 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX79737.1 - 0.00016 21.6 0.1 0.00075 19.4 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORX79737.1 - 0.011 16.4 0.6 0.49 11.1 0.1 2.8 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX79737.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein PAF-AH_p_II PF03403.13 ORX79738.1 - 4e-22 78.3 0.0 4.1e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX79738.1 - 0.0016 17.4 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORX79738.1 - 0.0018 17.6 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX79738.1 - 0.0041 17.8 0.2 0.0057 17.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORX79738.1 - 0.019 14.8 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX79738.1 - 0.031 13.9 0.1 0.4 10.3 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORX79738.1 - 0.046 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) PGAP1 PF07819.13 ORX79738.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein O-FucT PF10250.9 ORX79796.1 - 0.00053 19.8 1.0 0.0014 18.4 1.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 ORX79796.1 - 0.027 13.7 0.3 0.048 12.9 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 11 DUF4203 PF13886.6 ORX79799.1 - 1.5e-41 142.3 36.1 1.7e-41 142.1 36.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3040 PF11239.8 ORX79799.1 - 0.2 12.0 0.2 0.2 12.0 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) DUF4203 PF13886.6 ORX79800.1 - 4.8e-38 130.9 37.6 4.8e-38 130.9 37.6 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) UCR_UQCRX_QCR9 PF05365.12 ORX79800.1 - 0.61 10.1 6.5 0.73 9.8 0.4 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2101 PF09874.9 ORX79800.1 - 3.5 7.3 8.3 0.25 11.0 1.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) UPF0542 PF15086.6 ORX79801.1 - 1.5 8.8 3.5 7.7 6.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Myb_DNA-binding PF00249.31 ORX79864.1 - 5.7e-06 26.4 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORX79864.1 - 0.0025 17.7 0.1 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 Myb DNA-binding like BSP_II PF05432.11 ORX79864.1 - 0.021 14.6 0.6 0.032 14.0 0.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myb_DNA-bind_6 PF13921.6 ORX79864.1 - 0.032 14.5 1.4 0.07 13.4 0.0 2.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain PPV_E1_N PF00524.18 ORX79864.1 - 0.12 12.8 0.5 0.31 11.4 0.5 1.6 1 0 0 1 1 1 0 E1 Protein, N terminal domain SH3_1 PF00018.28 ORX79865.1 - 8.7e-13 47.7 0.0 6.8e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORX79865.1 - 2.4e-12 46.5 0.0 8.2e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORX79865.1 - 1.3e-11 43.9 0.7 0.00011 21.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 ORX79865.1 - 1.2e-07 31.7 0.1 2.8e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 ORX79865.1 - 0.0073 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 PB1 domain PI3K_p85B PF02192.16 ORX79865.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain WD40 PF00400.32 ORX79866.1 - 1.6e-34 117.3 25.0 2.3e-07 31.4 0.9 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX79866.1 - 8.2e-16 58.1 9.6 0.00012 22.3 0.0 5.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX79866.1 - 2.6e-09 37.2 0.7 6.5e-05 22.9 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX79866.1 - 1.7e-08 34.1 0.0 1.6e-07 31.0 0.0 2.1 1 1 0 2 2 2 1 WD40-like domain Frtz PF11768.8 ORX79866.1 - 2.6e-05 22.7 0.1 0.0065 14.8 0.0 2.7 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz CLTH PF10607.9 ORX79866.1 - 0.0013 18.6 2.2 0.0023 17.8 2.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Coatomer_WDAD PF04053.14 ORX79866.1 - 0.0026 16.9 0.3 0.039 13.0 0.0 2.4 2 1 0 3 3 3 1 Coatomer WD associated region Ge1_WD40 PF16529.5 ORX79866.1 - 0.0078 15.2 0.0 0.13 11.2 0.0 2.7 2 2 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORX79866.1 - 0.011 14.3 0.1 0.068 11.7 0.0 2.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 ORX79866.1 - 0.017 14.4 0.1 0.037 13.3 0.0 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Gmad1 PF10647.9 ORX79866.1 - 0.023 14.5 0.0 0.38 10.5 0.0 2.2 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Ras PF00071.22 ORX79867.1 - 6.2e-65 217.7 0.9 7.3e-65 217.5 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX79867.1 - 5.6e-37 126.6 0.5 9.9e-37 125.8 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX79867.1 - 8.7e-18 64.4 0.1 1.2e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX79867.1 - 1.6e-06 27.7 0.2 2.1e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX79867.1 - 6.3e-06 25.7 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX79867.1 - 1.6e-05 24.6 0.3 3.6e-05 23.4 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX79867.1 - 2.5e-05 24.3 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX79867.1 - 4.3e-05 23.5 0.8 0.14 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORX79867.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ORX79867.1 - 0.013 15.0 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 ORX79867.1 - 0.015 15.3 0.1 0.031 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ORX79867.1 - 0.033 14.7 0.0 0.058 13.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter YkpC PF17447.2 ORX79867.1 - 0.033 14.9 0.4 0.093 13.5 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized YkpC-like AAA PF00004.29 ORX79867.1 - 0.035 14.5 0.1 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX79867.1 - 0.039 14.2 0.0 0.065 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 ORX79867.1 - 0.05 12.9 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 ORX79867.1 - 0.059 13.1 0.3 1.2 8.9 0.0 2.4 1 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ORX79867.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 ORX79867.1 - 0.09 12.3 0.0 0.42 10.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 ORX79867.1 - 0.094 12.1 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 ORX79867.1 - 0.17 11.5 0.1 2.4 7.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain Pmp3 PF01679.17 ORX79868.1 - 8.7e-19 67.5 4.7 9.9e-19 67.3 4.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UFD1 PF03152.14 ORX79869.1 - 7.8e-79 263.1 0.0 8.9e-79 262.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 ORX79869.1 - 0.021 14.6 0.0 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.18 ORX79869.1 - 0.11 12.7 0.0 21 5.4 0.0 2.4 1 1 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain EFP_N PF08207.12 ORX79869.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain tRNA-synt_2b PF00587.25 ORX79870.1 - 3.2e-35 121.7 0.2 8.3e-35 120.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORX79870.1 - 1.3e-24 86.5 8.2 1.3e-24 86.5 8.2 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CotH PF08757.11 ORX79870.1 - 0.016 14.7 0.5 0.03 13.8 0.5 1.3 1 0 0 1 1 1 0 CotH kinase protein MreB_Mbl PF06723.13 ORX79870.1 - 0.3 9.9 2.7 0.44 9.3 2.7 1.1 1 0 0 1 1 1 0 MreB/Mbl protein UPF0231 PF06062.11 ORX79870.1 - 0.65 10.3 5.0 0.86 9.9 3.8 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Pkinase PF00069.25 ORX79871.1 - 3.7e-62 210.1 0.0 4.6e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX79871.1 - 3.8e-27 95.2 0.0 5.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX79871.1 - 1.3e-07 31.2 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX79871.1 - 7.2e-07 28.3 0.0 1.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORX79871.1 - 3.4e-05 23.3 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX79871.1 - 0.0005 20.1 0.0 0.0016 18.4 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX79871.1 - 0.06 12.9 0.1 0.098 12.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Arm PF00514.23 ORX79871.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Mito_carr PF00153.27 ORX79872.1 - 1.6e-70 233.1 0.9 2.5e-23 81.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 ORX79872.1 - 0.068 13.3 1.5 2.2 8.5 0.0 3.5 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif Myticin-prepro PF10690.9 ORX79902.1 - 0.0042 17.3 0.4 0.0065 16.7 0.4 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel RICTOR_N PF14664.6 ORX79907.1 - 0.052 12.5 0.0 0.052 12.5 0.0 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DJ-1_PfpI PF01965.24 ORX79908.1 - 2e-08 34.2 0.0 7.6e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX79908.1 - 0.0011 18.7 0.1 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX79908.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX79909.1 - 5.2e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX79909.1 - 0.00072 19.3 0.0 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX79909.1 - 0.0024 17.6 0.0 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 Latrotoxin C-terminal domain DLH PF01738.18 ORX79913.1 - 7.5e-08 32.2 0.1 3.3e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORX79913.1 - 1.1e-07 31.7 0.1 1.4e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORX79913.1 - 0.0005 18.9 0.3 0.0036 16.0 0.1 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 ORX79913.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORX79913.1 - 0.0052 16.7 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ORX79913.1 - 0.0067 15.9 0.1 0.046 13.2 0.0 2.2 2 1 1 3 3 3 1 Prolyl oligopeptidase family DUF1100 PF06500.11 ORX79913.1 - 0.055 12.3 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DJ-1_PfpI PF01965.24 ORX79914.1 - 5.1e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX79914.1 - 0.00052 19.8 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX79914.1 - 0.0027 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain HSF_DNA-bind PF00447.17 ORX79944.1 - 8.6e-33 112.8 4.6 8.6e-33 112.8 4.6 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 ORX79944.1 - 0.024 15.1 0.1 0.2 12.1 0.0 2.5 2 1 1 3 3 3 0 Ets-domain Lip_prot_lig_C PF10437.9 ORX79944.1 - 0.043 13.8 0.1 0.42 10.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus B12D PF06522.11 ORX79945.1 - 1.6e-16 59.8 0.1 2e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Scs3p PF10261.9 ORX79946.1 - 2.8e-47 161.3 23.0 2.1e-36 125.7 8.3 2.7 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_L24e PF01246.20 ORX79947.1 - 4.2e-33 113.4 0.3 4.2e-33 113.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CDPS PF16715.5 ORX79947.1 - 0.49 10.0 6.2 0.71 9.5 6.2 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase DDHD PF02862.17 ORX79947.1 - 0.96 9.6 5.4 1.2 9.2 5.4 1.0 1 0 0 1 1 1 0 DDHD domain GPI-anchored PF10342.9 ORX79948.1 - 2.7e-06 28.0 0.2 8.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 ORX79948.1 - 7 5.7 8.9 7.3 5.7 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Polysacc_lyase PF14099.6 ORX79949.1 - 0.0058 16.5 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase Tetraspanin PF00335.20 ORX79950.1 - 5.7e-08 32.7 16.6 1.1e-07 31.9 16.6 1.4 1 1 0 1 1 1 1 Tetraspanin family IBN_N PF03810.19 ORX79950.1 - 0.13 12.2 0.1 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 Importin-beta N-terminal domain Na_K-ATPase PF00287.18 ORX79950.1 - 0.16 11.1 0.6 0.29 10.3 0.6 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF4500 PF14937.6 ORX79950.1 - 1.8 8.7 4.9 4.1 7.5 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4500) Peptidase_M28 PF04389.17 ORX79952.1 - 1.1e-42 146.0 0.0 1.6e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX79952.1 - 1.1e-14 54.2 0.3 3.3e-14 52.7 0.3 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 ORX79952.1 - 5.5e-05 22.3 0.0 0.0052 15.9 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORX79952.1 - 0.00035 20.3 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 B12-binding PF02310.19 ORX79952.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain PDZ_1 PF12812.7 ORX79953.1 - 6.8e-35 118.9 0.0 8e-23 80.3 0.0 3.0 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORX79953.1 - 1.4e-21 77.9 0.0 1.5e-17 64.9 0.0 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ORX79953.1 - 4.1e-16 58.6 0.0 3.8e-07 29.9 0.0 4.8 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 ORX79953.1 - 3.6e-15 56.0 0.1 1.6e-05 25.2 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORX79953.1 - 5e-12 46.0 0.0 0.0011 19.3 0.0 3.7 3 0 0 3 3 3 3 PDZ domain HLH PF00010.26 ORX79954.1 - 1e-11 44.6 0.8 2.2e-11 43.5 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 ORX79954.1 - 0.0066 16.6 7.2 0.017 15.3 0.7 3.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper KASH_CCD PF14662.6 ORX79954.1 - 0.042 13.7 3.2 0.062 13.1 3.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CCDC92 PF14916.6 ORX79954.1 - 0.051 13.4 0.8 0.2 11.4 0.8 2.1 1 1 0 1 1 1 0 Coiled-coil domain of unknown function DUF2381 PF09544.10 ORX79954.1 - 0.088 12.3 1.1 0.14 11.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) FlaC_arch PF05377.11 ORX79954.1 - 0.11 12.9 0.1 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 ORX79954.1 - 0.16 12.1 5.3 0.16 12.1 1.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Glyco_transf_20 PF00982.21 ORX80015.1 - 5.9e-166 552.8 0.0 8e-166 552.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORX80015.1 - 8.6e-75 250.9 0.0 1.5e-74 250.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORX80015.1 - 0.0032 17.2 0.0 0.7 9.6 0.0 2.6 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF883 PF05957.13 ORX80016.1 - 0.00088 19.8 1.5 0.00088 19.8 1.5 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Histidinol_dh PF00815.20 ORX80016.1 - 0.0058 15.7 1.7 0.0065 15.5 1.7 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PLC-beta_C PF08703.10 ORX80016.1 - 0.016 15.2 3.6 0.04 13.9 3.6 1.6 1 1 0 1 1 1 0 PLC-beta C terminal FIVAR PF07554.13 ORX80016.1 - 0.032 15.0 3.0 0.04 14.7 3.0 1.2 1 0 0 1 1 1 0 FIVAR domain DUF5486 PF17588.2 ORX80016.1 - 0.047 13.6 1.3 0.072 13.0 0.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5486) YtxH PF12732.7 ORX80016.1 - 0.05 14.1 4.5 0.1 13.2 4.5 1.7 1 1 0 1 1 1 0 YtxH-like protein ASPRs PF17641.2 ORX80016.1 - 0.052 13.8 0.3 0.059 13.6 0.3 1.0 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related AIP3 PF03915.13 ORX80017.1 - 6.7e-86 288.9 11.4 8.4e-86 288.6 11.4 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 MREG PF15812.5 ORX80017.1 - 0.29 11.4 2.3 0.29 11.4 0.4 1.9 2 0 0 2 2 2 0 Melanoregulin Fib_alpha PF08702.10 ORX80017.1 - 0.66 10.2 12.6 0.061 13.5 4.5 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORX80017.1 - 9.3 6.8 12.1 45 4.6 0.0 5.0 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein SDF PF00375.18 ORX80018.1 - 1.7e-49 168.9 12.7 1.8e-49 168.8 12.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Chitin_synth_2 PF03142.15 ORX80044.1 - 4.2e-258 857.3 0.3 5.1e-258 857.0 0.3 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX80044.1 - 2.5e-11 43.9 13.9 1.2e-10 41.7 13.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX80044.1 - 6.5e-11 42.5 0.0 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX80044.1 - 3e-06 26.8 0.1 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX80044.1 - 0.00063 19.6 0.0 0.076 12.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Man-6-P_recep PF02157.15 ORX80046.1 - 2.4e-24 85.8 0.0 2.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 ORX80046.1 - 2.1e-18 66.8 0.1 7.3e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 ORX80046.1 - 1.8e-14 54.2 0.0 3.7e-14 53.2 0.0 1.4 1 1 1 2 2 2 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 ORX80046.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein PMP1_2 PF08114.11 ORX80046.1 - 0.053 13.3 2.6 0.083 12.6 2.6 1.3 1 0 0 1 1 1 0 ATPase proteolipid family TPR_1 PF00515.28 ORX80047.1 - 6e-23 79.7 4.2 1.5e-05 24.6 0.2 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORX80047.1 - 2.8e-16 58.2 7.9 0.00013 21.8 0.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX80047.1 - 3.4e-15 55.4 13.2 0.00023 20.8 0.3 5.6 3 2 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 ORX80047.1 - 3.7e-14 52.0 5.4 0.0021 18.3 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX80047.1 - 1.3e-12 46.8 7.1 0.0063 16.6 0.1 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX80047.1 - 2e-10 40.6 5.6 0.047 14.5 0.0 6.2 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORX80047.1 - 2.5e-10 40.7 7.9 1.1e-05 25.9 0.2 4.7 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX80047.1 - 3.2e-10 40.5 1.6 0.0074 16.9 0.0 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX80047.1 - 3.8e-09 36.7 6.3 0.00023 21.4 1.2 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 ORX80047.1 - 6.2e-09 36.1 1.2 0.0063 16.8 0.1 4.4 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX80047.1 - 2.8e-07 30.6 0.6 0.0022 18.1 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORX80047.1 - 1.6e-06 27.7 4.4 0.013 15.5 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX80047.1 - 7e-06 26.2 7.5 0.00087 19.5 2.5 2.9 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF1641 PF07849.11 ORX80047.1 - 3.6e-05 23.6 0.1 0.0025 17.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1641) TPR_4 PF07721.14 ORX80047.1 - 0.016 15.8 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX80047.1 - 0.028 14.3 2.7 0.39 10.6 0.8 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX80047.1 - 0.038 14.6 1.6 4.6 8.1 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Octopine_DH PF02317.17 ORX80047.1 - 0.097 12.8 0.4 0.71 10.0 0.0 2.5 3 0 0 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF5578 PF17741.1 ORX80047.1 - 0.2 11.0 0.1 1.3 8.4 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5578) FAD_binding_3 PF01494.19 ORX80049.1 - 6.2e-08 32.3 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ORX80049.1 - 0.0028 16.8 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Peptidase_S28 PF05577.12 ORX80049.1 - 0.064 12.0 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF21 PF01595.20 ORX80050.1 - 0.023 14.4 3.5 0.037 13.8 3.5 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Amastin PF07344.11 ORX80050.1 - 0.12 12.2 5.9 0.18 11.7 5.9 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein VirB8 PF04335.13 ORX80050.1 - 0.26 11.1 0.1 0.26 11.1 0.1 1.5 2 0 0 2 2 2 0 VirB8 protein F-box PF00646.33 ORX80051.1 - 3.9e-05 23.4 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX80051.1 - 0.00026 20.8 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORX80051.1 - 0.0057 16.5 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 F-box HLH PF00010.26 ORX80051.1 - 0.089 12.8 0.1 0.69 9.9 0.0 2.4 3 1 0 3 3 3 0 Helix-loop-helix DNA-binding domain Chitin_synth_2 PF03142.15 ORX80052.1 - 3e-280 930.3 1.9 4.4e-280 929.8 1.9 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX80052.1 - 5.3e-14 52.7 0.0 1.2e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX80052.1 - 1.6e-12 47.8 5.8 1.6e-12 47.8 5.8 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX80052.1 - 3.3e-05 23.4 0.1 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX80052.1 - 0.017 14.9 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2207 PF09972.9 ORX80052.1 - 2.7 6.6 4.2 27 3.3 2.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) zf-C2H2 PF00096.26 ORX80053.1 - 6.2e-12 45.3 19.4 0.00054 20.3 1.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX80053.1 - 1.1e-10 41.4 7.3 1.2e-05 25.5 1.4 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX80053.1 - 5.1e-10 39.3 17.4 0.00073 20.2 2.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX80053.1 - 0.00049 20.3 5.1 0.021 15.1 1.1 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX80053.1 - 0.016 15.5 3.0 0.016 15.5 3.0 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX80053.1 - 0.024 14.4 2.2 0.024 14.4 2.2 3.2 3 1 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORX80053.1 - 0.026 14.5 15.0 3 8.0 0.3 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 ORX80053.1 - 0.05 13.2 4.4 0.46 10.1 0.3 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 ORX80053.1 - 0.066 13.1 4.3 0.078 12.9 2.5 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.7 ORX80053.1 - 0.11 13.0 9.0 7 7.2 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORX80053.1 - 0.21 12.1 12.5 0.71 10.4 1.7 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 ORX80053.1 - 0.37 10.4 6.3 1.6 8.4 2.3 2.9 2 1 0 2 2 2 0 MYST family zinc finger domain GAGA PF09237.11 ORX80053.1 - 1.9 8.4 6.2 0.24 11.3 1.1 2.1 1 1 1 2 2 2 0 GAGA factor zf_ZIC PF18366.1 ORX80053.1 - 2.4 8.4 5.8 6.9 6.9 0.2 2.9 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 ORX80053.1 - 2.7 7.8 16.1 1.6 8.5 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain C1_4 PF07975.12 ORX80053.1 - 3 8.1 9.1 0.14 12.5 1.5 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Orn_Arg_deC_N PF02784.16 ORX80054.1 - 5.9e-67 225.6 0.0 7.2e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORX80054.1 - 4.2e-17 62.2 0.0 4.9e-17 62.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Polysacc_deac_1 PF01522.21 ORX80090.1 - 8.4e-25 87.1 0.0 1.7e-24 86.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX80090.1 - 0.0098 15.1 0.0 0.045 13.0 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX80090.1 - 0.047 13.3 0.2 0.18 11.5 0.1 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Ribosomal_L7Ae PF01248.26 ORX80091.1 - 2.6e-24 84.8 0.0 3e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF448 PF04296.13 ORX80092.1 - 2.8e-06 27.1 0.1 6e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF448) Pkr1 PF08636.10 ORX80094.1 - 1.7e-20 72.9 1.4 1.9e-20 72.7 1.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF2107 PF09880.9 ORX80094.1 - 0.038 14.1 0.2 0.05 13.7 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) Auxin_repressed PF05564.12 ORX80094.1 - 0.14 12.8 0.0 0.19 12.4 0.0 1.2 1 0 0 1 1 1 0 Dormancy/auxin associated protein GFO_IDH_MocA PF01408.22 ORX80095.1 - 5.1e-09 37.0 0.0 4e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX80095.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 ORX80119.1 - 3e-60 204.4 21.7 3.7e-60 204.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX80119.1 - 2e-28 99.3 26.9 2.6e-28 99.0 25.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX80119.1 - 3.4e-06 26.6 4.0 6.8e-06 25.6 4.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX80119.1 - 9.4e-05 21.1 9.7 9.4e-05 21.1 9.7 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORX80119.1 - 0.0048 16.5 0.4 0.058 13.0 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORX80119.1 - 0.46 8.7 10.5 0.44 8.8 3.9 2.9 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.6 ORX80119.1 - 6.9 6.3 11.8 2.5 7.7 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Lipase_3 PF01764.25 ORX80120.1 - 3.2e-18 66.0 0.0 8.4e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) TGF_beta_GS PF08515.12 ORX80120.1 - 0.018 14.6 0.1 0.055 13.0 0.1 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Hydrolase_4 PF12146.8 ORX80120.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX80120.1 - 0.18 12.4 0.4 0.35 11.4 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribonuclease_3 PF00636.26 ORX80122.1 - 1.4e-34 118.8 0.1 1.2e-16 61.2 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ORX80122.1 - 6.2e-17 62.0 0.0 1.7e-11 44.4 0.0 2.5 2 1 0 2 2 2 2 Ribonuclease-III-like MFS_1 PF07690.16 ORX80152.1 - 2.3e-41 141.9 26.6 2.9e-41 141.6 26.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ORX80152.1 - 7.6 4.7 14.3 0.76 8.0 0.7 2.7 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-MIZ PF02891.20 ORX80153.1 - 4.8e-16 58.2 6.7 1.2e-15 56.9 6.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORX80153.1 - 7.4e-06 25.7 2.0 1.4e-05 24.8 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF155 PF02582.14 ORX80154.1 - 1.3e-54 184.9 0.7 2.3e-54 184.1 0.7 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF155 PF02582.14 ORX80155.1 - 7.6e-55 185.7 0.2 1.2e-54 185.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-CCCH PF00642.24 ORX80182.1 - 2.4e-08 33.7 8.8 9.2e-06 25.4 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX80182.1 - 1.3e-05 25.0 7.2 0.019 15.0 1.9 2.4 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 ORX80182.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 ORX80182.1 - 0.00023 21.8 6.9 0.19 12.4 0.0 3.5 3 0 0 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 ORX80182.1 - 0.031 14.1 2.1 0.031 14.1 2.1 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Orthopox_F6 PF06601.12 ORX80182.1 - 0.086 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Orthopoxvirus F6 protein zf-CCCH_2 PF14608.6 ORX80182.1 - 3.1 8.4 7.3 9.6 6.9 0.2 3.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CLASP_N PF12348.8 ORX80183.1 - 4.4e-08 33.0 0.0 5.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal MFMR_assoc PF16596.5 ORX80183.1 - 0.31 11.5 7.3 0.55 10.7 7.3 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR NARG2_C PF10505.9 ORX80184.1 - 3.9e-13 49.4 0.0 5.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus BC10 PF06726.12 ORX80185.1 - 1.2e-14 54.2 6.2 1.8e-14 53.7 6.2 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 MFS_1 PF07690.16 ORX80186.1 - 1.4e-48 165.7 27.6 1.4e-48 165.7 27.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX80186.1 - 2.2e-11 43.3 20.3 2.3e-10 39.9 20.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORX80186.1 - 1.4e-05 24.1 13.0 0.058 12.2 0.6 3.6 4 0 0 4 4 4 3 MFS_1 like family MFS_3 PF05977.13 ORX80186.1 - 3.8e-05 22.3 0.4 8.7e-05 21.1 0.4 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 ORX80186.1 - 0.032 12.5 15.0 0.0051 15.2 6.9 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_Omp PF13488.6 ORX80186.1 - 4.2 7.4 7.7 5.4 7.1 0.4 3.2 3 0 0 3 3 3 0 Glycine zipper Forkhead PF00250.18 ORX80187.1 - 2.7e-35 120.5 0.4 3e-35 120.4 0.4 1.0 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 ORX80187.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 linker histone H1 and H5 family G-gamma PF00631.22 ORX80188.1 - 2.1e-09 37.3 0.1 2.8e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 GGL domain Polysacc_deac_1 PF01522.21 ORX80189.1 - 6.4e-30 103.6 0.1 9e-30 103.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX80189.1 - 1.8e-10 41.1 39.2 1.7e-05 25.2 17.3 2.3 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 ORX80189.1 - 0.0021 17.3 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX80189.1 - 0.0064 16.2 0.6 0.016 14.9 0.6 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) BAG PF02179.16 ORX80190.1 - 7e-10 39.2 0.1 1.6e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 BAG domain IQCJ-SCHIP1 PF15157.6 ORX80190.1 - 0.022 14.6 1.2 0.022 14.6 1.2 2.1 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF5617 PF18493.1 ORX80190.1 - 0.41 10.8 3.8 14 5.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) WD40 PF00400.32 ORX80217.1 - 0.0012 19.6 0.4 0.0025 18.6 0.4 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat PAP2 PF01569.21 ORX80218.1 - 7.8e-15 54.8 6.4 1.6e-14 53.8 6.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily RRM_2 PF04059.12 ORX80218.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 MgtE PF01769.16 ORX80218.1 - 5.3 7.4 14.0 0.15 12.4 3.4 2.4 1 1 1 2 2 2 0 Divalent cation transporter CBFD_NFYB_HMF PF00808.23 ORX80219.1 - 2.6e-28 98.1 0.6 4.4e-28 97.4 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX80219.1 - 3.7e-06 27.3 0.1 6.9e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORX80219.1 - 0.0031 17.6 0.7 0.0043 17.1 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 ORX80219.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.16 ORX80219.1 - 0.032 14.2 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-X PF09415.10 ORX80219.1 - 0.04 14.2 0.1 0.078 13.3 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Na_Ca_ex PF01699.24 ORX80220.1 - 1.4e-35 122.4 44.3 9.8e-18 64.6 23.3 4.0 5 0 0 5 5 5 3 Sodium/calcium exchanger protein Ribosomal_S26e PF01283.19 ORX80221.1 - 1.7e-54 182.8 6.4 2e-54 182.6 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 ORX80221.1 - 0.054 14.1 2.2 0.74 10.4 1.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Not3 PF04065.15 ORX80222.1 - 2.7e-87 292.0 30.6 2.7e-87 292.0 30.6 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ORX80222.1 - 1.6e-45 154.4 13.4 5.4e-45 152.7 13.4 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 ORX80222.1 - 0.028 14.8 7.0 0.1 13.0 7.0 2.0 1 0 0 1 1 1 0 Syntaxin-like protein DUF19 PF01579.18 ORX80222.1 - 0.56 10.0 5.3 1.1 9.0 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) DUF4407 PF14362.6 ORX80222.1 - 6.6 6.0 7.5 11 5.3 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1957 PF09210.11 ORX80222.1 - 7.2 7.1 11.0 0.35 11.3 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1957) Ribosomal_L12 PF00542.19 ORX80223.1 - 2.2e-22 79.2 8.5 1.5e-21 76.5 4.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ORX80223.1 - 4.7e-16 58.2 0.8 4.7e-16 58.2 0.8 2.6 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Cas_Csy2 PF09614.10 ORX80223.1 - 0.072 12.4 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) CsbD PF05532.12 ORX80224.1 - 2e-07 30.8 0.2 6.2e-07 29.2 0.2 1.8 1 0 0 1 1 1 1 CsbD-like Tox-MPTase5 PF15641.6 ORX80224.1 - 0.03 14.4 0.7 6.8 6.8 0.0 3.2 2 0 0 2 2 2 0 Metallopeptidase toxin 5 DUF4148 PF13663.6 ORX80224.1 - 2 8.7 6.4 5.3 7.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) FAD_binding_4 PF01565.23 ORX80226.1 - 6.3e-21 74.6 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyclin PF08613.11 ORX80251.1 - 1.8e-12 47.9 0.3 3.5e-12 47.0 0.3 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX80251.1 - 0.00095 18.9 0.2 0.0018 18.0 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX80252.1 - 1.4e-09 38.5 0.0 4e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin PF08613.11 ORX80253.1 - 3.1e-09 37.4 0.3 5.2e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Cyclin Arrestin_C PF02752.22 ORX80254.1 - 9.1e-08 32.6 0.0 3.8e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX80254.1 - 2.9e-06 27.4 0.0 7.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GATA PF00320.27 ORX80255.1 - 2.5e-15 55.8 7.8 4.2e-15 55.0 7.8 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORX80255.1 - 3.2e-12 46.6 0.0 5.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORX80255.1 - 2.2e-08 34.1 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORX80255.1 - 9.6e-08 32.2 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX80255.1 - 5e-06 26.7 0.0 8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORX80255.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 PAS domain PknG_rubred PF16919.5 ORX80255.1 - 0.018 15.2 1.2 0.035 14.3 1.2 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DZR PF12773.7 ORX80255.1 - 0.037 14.0 0.8 0.093 12.8 0.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon PAS_11 PF14598.6 ORX80255.1 - 0.046 13.8 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain zf-NADH-PPase PF09297.11 ORX80255.1 - 0.86 9.3 4.6 7.9 6.2 4.6 2.3 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Thiol_cytolysin PF01289.19 ORX80278.1 - 1.2e-25 90.2 0.0 1.6e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Thiol-activated cytolysin Ank_4 PF13637.6 ORX80279.1 - 3.6e-13 49.8 2.7 1.4e-06 28.7 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX80279.1 - 1.5e-12 46.5 0.6 3.2e-06 27.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORX80279.1 - 3.5e-12 46.7 0.1 2.2e-08 34.5 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORX80279.1 - 6.2e-09 35.9 2.7 0.00012 22.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORX80279.1 - 4.3e-08 33.3 0.5 0.0026 18.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) V-SNARE PF05008.15 ORX80280.1 - 1.1e-18 67.4 5.5 1.3e-18 67.1 0.5 2.8 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORX80280.1 - 1.3e-18 67.0 5.9 1.3e-18 67.0 5.9 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus EzrA PF06160.12 ORX80280.1 - 0.039 12.1 0.5 0.096 10.8 0.1 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF883 PF05957.13 ORX80280.1 - 0.092 13.4 6.2 0.81 10.3 0.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 ORX80280.1 - 0.13 12.3 1.2 9.5 6.3 0.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 ORX80280.1 - 0.17 12.0 2.1 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Nbl1_Borealin_N PF10444.9 ORX80280.1 - 0.39 10.4 3.1 0.41 10.3 0.3 2.4 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal Exonuc_VII_L PF02601.15 ORX80280.1 - 1.3 8.5 6.4 3.1 7.3 6.4 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 ORX80280.1 - 1.7 8.9 8.9 0.3 11.3 2.0 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 LMBR1 PF04791.16 ORX80281.1 - 1.9e-28 99.7 24.1 8.7e-16 57.9 13.4 2.1 1 1 0 2 2 2 2 LMBR1-like membrane protein Arrestin_C PF02752.22 ORX80282.1 - 5.5e-12 46.3 0.0 1.1e-10 42.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX80282.1 - 3.7e-11 43.3 0.1 1.2e-09 38.4 0.1 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX80282.1 - 0.00022 21.0 0.2 0.00065 19.5 0.0 1.8 3 0 0 3 3 3 1 Arrestin_N terminal like Thioredoxin PF00085.20 ORX80283.1 - 1.7e-67 223.9 5.0 3.5e-31 107.2 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 ORX80283.1 - 8e-49 166.1 9.3 8.7e-41 139.9 4.3 3.4 2 2 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 ORX80283.1 - 7.3e-15 54.9 4.6 8.6e-14 51.4 3.1 2.6 2 1 1 3 3 3 1 Calsequestrin Thioredoxin_2 PF13098.6 ORX80283.1 - 2.3e-09 37.7 1.5 0.0024 18.3 0.1 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ORX80283.1 - 3.6e-09 36.4 2.6 0.0004 19.8 0.0 3.1 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORX80283.1 - 1.7e-07 31.3 0.1 0.013 15.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 ORX80283.1 - 1.7e-07 31.4 2.2 0.25 11.7 0.0 5.1 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 ORX80283.1 - 1.6e-06 28.1 0.1 0.039 13.9 0.0 2.9 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 ORX80283.1 - 1.4e-05 25.2 2.2 0.29 11.3 0.0 4.4 4 1 0 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 ORX80283.1 - 0.00023 20.9 0.9 0.28 10.9 0.0 3.2 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.6 ORX80283.1 - 0.0032 17.7 1.1 5.1 7.2 0.0 3.7 4 0 0 4 4 4 1 Thioredoxin TraF PF13728.6 ORX80283.1 - 0.0072 16.2 0.1 0.086 12.6 0.0 2.7 3 0 0 3 3 3 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 ORX80283.1 - 0.01 16.0 1.1 29 5.0 0.0 3.9 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_5 PF13743.6 ORX80283.1 - 0.058 13.1 1.8 18 4.9 0.0 3.6 2 2 2 4 4 4 0 Thioredoxin RMI1_N PF08585.12 ORX80284.1 - 1.2e-39 136.4 0.5 3.4e-39 134.9 0.1 1.9 2 0 0 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 ORX80284.1 - 2.7e-08 33.8 0.0 5.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Sel1 PF08238.12 ORX80285.1 - 3.4e-122 396.1 61.5 1.4e-10 41.5 0.1 14.8 15 0 0 15 15 15 14 Sel1 repeat Astro_capsid_p2 PF16580.5 ORX80285.1 - 0.19 11.2 0.1 10 5.5 0.0 2.7 2 1 0 2 2 2 0 C-terminal tail of astrovirus capsid projection or spike GSu_C4xC__C2xCH PF09698.10 ORX80285.1 - 2 9.3 11.1 13 6.7 0.1 5.1 6 0 0 6 6 6 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) zf-RING_2 PF13639.6 ORX80286.1 - 1.5e-11 44.5 10.1 2e-11 44.0 9.0 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX80286.1 - 1.1e-09 38.0 8.2 2.9e-09 36.6 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX80286.1 - 7.2e-09 35.2 2.0 1e-08 34.7 0.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORX80286.1 - 4.6e-07 29.6 6.6 1.1e-06 28.4 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX80286.1 - 1.8e-06 28.1 10.1 4.7e-06 26.8 10.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORX80286.1 - 4.3e-06 26.6 0.8 4.3e-06 26.6 0.8 3.0 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX80286.1 - 0.00014 21.7 6.3 0.00031 20.6 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORX80286.1 - 0.00053 20.0 3.6 0.0011 18.9 3.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORX80286.1 - 0.051 13.4 11.4 0.95 9.4 11.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 ORX80286.1 - 0.067 13.5 5.4 0.64 10.4 4.8 2.5 1 1 1 2 2 2 0 RING-like domain zf-Nse PF11789.8 ORX80286.1 - 0.077 12.8 2.9 0.15 11.9 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 ORX80286.1 - 0.33 10.6 5.7 0.78 9.4 5.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORX80286.1 - 0.44 10.7 7.9 0.4 10.8 5.9 2.0 2 1 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 ORX80286.1 - 2.2 8.5 6.7 12 6.1 6.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Proteasom_Rpn13 PF04683.13 ORX80287.1 - 6.5e-29 100.3 0.2 1.1e-28 99.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 ORX80287.1 - 1.8e-26 92.5 1.9 3.5e-26 91.6 1.9 1.5 1 0 0 1 1 1 1 UCH-binding domain Ribosomal_L19e PF01280.20 ORX80288.1 - 1.2e-52 177.8 8.4 1.2e-52 177.8 8.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e TFA2_Winged_2 PF18121.1 ORX80289.1 - 1.7e-20 72.5 0.3 3.6e-20 71.4 0.3 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 ORX80289.1 - 2.8e-14 53.1 0.5 7.6e-14 51.8 0.5 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain RPA_C PF08784.11 ORX80289.1 - 0.12 13.0 0.4 0.49 11.1 0.0 2.0 2 1 1 3 3 3 0 Replication protein A C terminal Coatomer_WDAD PF04053.14 ORX80290.1 - 1.4e-169 564.9 0.3 6.1e-169 562.8 0.0 2.0 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 ORX80290.1 - 1.2e-37 127.2 14.1 5.1e-07 30.3 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 ORX80290.1 - 0.0023 17.9 0.1 5.2 7.2 0.0 4.0 2 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 ORX80290.1 - 0.0081 14.9 2.2 10 4.6 0.0 4.0 2 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORX80290.1 - 0.062 12.3 1.6 3.4 6.6 0.0 3.0 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BLUF PF04940.12 ORX80290.1 - 0.14 12.3 0.0 36 4.6 0.0 3.2 3 0 0 3 3 3 0 Sensors of blue-light using FAD Clathrin PF00637.20 ORX80290.1 - 0.51 10.2 3.3 0.37 10.7 0.6 2.1 2 1 0 2 2 2 0 Region in Clathrin and VPS Fungal_trans PF04082.18 ORX80291.1 - 1.2e-28 99.9 0.0 2.5e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX80291.1 - 6.2e-11 42.2 9.9 1.1e-10 41.4 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 ORX80292.1 - 1.4e-31 107.7 11.7 1.7e-16 59.5 2.7 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX80292.1 - 5.4e-07 29.0 8.2 0.0024 17.4 1.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORX80292.1 - 0.011 15.9 6.0 0.46 10.7 0.5 2.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ORX80292.1 - 1.5 8.7 6.0 1 9.3 0.9 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 ORX80292.1 - 1.8 8.8 15.0 0.3 11.3 1.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Prim_Zn_Ribbon PF08273.12 ORX80292.1 - 2.3 8.6 12.5 3.2 8.1 4.3 3.0 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase Opi1 PF08618.10 ORX80293.1 - 2.6e-76 257.5 10.2 4.2e-47 161.4 3.1 3.0 1 1 2 3 3 3 3 Transcription factor Opi1 Perilipin PF03036.16 ORX80293.1 - 0.0002 20.5 0.3 0.00083 18.5 0.0 2.1 2 1 0 2 2 2 1 Perilipin family DUF4796 PF16044.5 ORX80293.1 - 0.049 13.2 0.2 2 8.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4796) Citrate_synt PF00285.21 ORX80293.1 - 0.11 11.5 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Velvet PF11754.8 ORX80294.1 - 1e-36 127.2 0.8 1.2e-36 126.9 0.8 1.0 1 0 0 1 1 1 1 Velvet factor DUF4505 PF14956.6 ORX80294.1 - 0.03 14.1 0.1 0.034 13.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) COX3 PF00510.18 ORX80318.1 - 4.2e-31 108.7 5.4 4.9e-31 108.5 5.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III PIG-P PF08510.12 ORX80318.1 - 0.058 13.3 0.6 0.14 12.1 0.6 1.7 1 0 0 1 1 1 0 PIG-P DUF3810 PF12725.7 ORX80318.1 - 0.48 9.7 2.8 0.51 9.6 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF900 PF05990.12 ORX80346.1 - 1.9e-05 24.3 0.0 4.3e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF726 PF05277.12 ORX80346.1 - 2.8e-05 23.2 0.0 3.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.25 ORX80346.1 - 0.0046 16.8 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 ORX80346.1 - 0.0075 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 ORX80346.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase UPF0020 PF01170.18 ORX80347.1 - 2e-07 30.9 0.0 5e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 ORX80347.1 - 0.025 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Mcl1_mid PF12341.8 ORX80348.1 - 1.8e-96 323.0 0.1 4.4e-92 308.6 0.1 2.4 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 ORX80348.1 - 9.6e-20 70.6 12.0 1.2e-05 25.9 0.2 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX80348.1 - 2.1e-15 56.8 2.0 0.00019 21.7 0.0 5.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX80348.1 - 2.2e-05 24.4 0.0 0.11 12.3 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 ORX80348.1 - 0.61 9.8 4.9 4.1 7.1 0.0 3.6 4 0 0 4 4 4 0 TUP1-like enhancer of split G-gamma PF00631.22 ORX80349.1 - 1.3e-14 53.9 0.0 1.4e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain CAP_GLY PF01302.25 ORX80350.1 - 1.6e-19 69.7 0.3 2.8e-19 68.9 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 ORX80350.1 - 2.4e-12 46.9 6.8 2e-05 24.8 0.1 5.1 3 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX80350.1 - 2.6e-12 46.3 4.8 3.3e-07 30.0 1.6 4.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 ORX80350.1 - 9.6e-07 28.5 0.6 4e-05 23.2 0.0 3.3 2 1 0 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 ORX80350.1 - 0.00041 20.2 3.3 34 4.8 0.3 6.1 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 ORX80350.1 - 0.00067 19.9 7.9 22 6.1 0.2 6.5 6 1 0 6 6 6 1 Leucine Rich Repeat Ubiquitin_2 PF14560.6 ORX80350.1 - 0.0041 17.5 0.2 0.0095 16.4 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3752 PF12572.8 ORX80351.1 - 2.4e-28 99.6 9.2 2.4e-28 99.6 9.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Mod_r PF07200.13 ORX80352.1 - 1.7e-30 106.1 14.3 2.1e-30 105.8 14.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Bacillus_HBL PF05791.11 ORX80352.1 - 0.0078 16.1 3.4 0.014 15.2 2.6 1.7 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Chromo_2 PF18704.1 ORX80352.1 - 0.056 13.7 0.9 0.1 12.8 0.1 1.8 2 0 0 2 2 2 0 Chromatin organization modifier domain 2 Cytochrom_B562 PF07361.11 ORX80352.1 - 0.079 13.6 2.5 0.58 10.8 0.1 2.4 1 1 1 2 2 2 0 Cytochrome b562 Mating_N PF12731.7 ORX80352.1 - 0.093 12.8 1.8 0.92 9.6 0.0 2.6 2 1 1 3 3 3 0 Mating-type protein beta 1 LIM PF00412.22 ORX80353.1 - 0.018 15.3 0.8 0.034 14.4 0.8 1.4 1 0 0 1 1 1 0 LIM domain zf-RRN7 PF11781.8 ORX80353.1 - 0.87 9.3 7.1 0.17 11.6 2.8 2.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SH3_1 PF00018.28 ORX80354.1 - 1.5e-06 27.7 0.0 7.6e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORX80354.1 - 7.7e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX80354.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF308 PF03729.13 ORX80354.1 - 0.15 12.4 4.5 0.25 11.7 0.1 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) RTT107_BRCT_5 PF16770.5 ORX80355.1 - 3.3e-09 36.5 0.0 8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 ORX80355.1 - 1.5e-08 34.8 0.0 2e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORX80355.1 - 0.022 14.7 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 ORX80355.1 - 0.04 14.3 0.1 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain CMAS PF02353.20 ORX80379.1 - 6.2e-65 219.2 0.7 7.6e-65 218.9 0.7 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ORX80379.1 - 1.6e-11 44.7 0.0 3.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX80379.1 - 5.5e-11 43.0 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX80379.1 - 2.2e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX80379.1 - 4.8e-06 26.4 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX80379.1 - 6.1e-05 23.7 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 ORX80379.1 - 0.00014 21.5 0.1 0.00022 20.8 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 ORX80379.1 - 0.00084 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ORX80379.1 - 0.0049 16.7 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 ORX80379.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Carn_acyltransf PF00755.20 ORX80380.1 - 1e-184 615.5 0.0 1.1e-184 615.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Polysacc_deac_1 PF01522.21 ORX80381.1 - 2.1e-31 108.4 0.0 3.7e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX80381.1 - 3.1e-18 66.0 35.5 7.7e-09 35.9 11.7 2.3 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 ORX80381.1 - 0.00035 19.9 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX80381.1 - 0.00049 19.8 0.1 0.00088 19.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) YabA PF06156.13 ORX80381.1 - 0.033 14.8 0.3 0.25 12.0 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX80382.1 - 2.1e-31 108.4 0.0 3.7e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX80382.1 - 5.6e-18 65.1 35.7 7.7e-09 35.9 11.7 2.3 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 ORX80382.1 - 0.00035 19.9 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX80382.1 - 0.00049 19.8 0.1 0.00088 19.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) YabA PF06156.13 ORX80382.1 - 0.033 14.8 0.3 0.25 12.0 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX80383.1 - 2.1e-31 108.4 0.0 3.7e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX80383.1 - 3.1e-18 66.0 35.5 7.7e-09 35.9 11.7 2.3 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 ORX80383.1 - 0.00035 19.9 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX80383.1 - 0.00049 19.8 0.1 0.00088 19.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) YabA PF06156.13 ORX80383.1 - 0.033 14.8 0.3 0.25 12.0 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Tim44 PF04280.15 ORX80384.1 - 6.9e-08 32.7 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain Myticin-prepro PF10690.9 ORX80388.1 - 0.0021 18.2 0.3 0.0033 17.6 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel adh_short PF00106.25 ORX80389.1 - 1.9e-30 105.8 0.0 9.5e-23 80.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX80389.1 - 1.2e-21 77.4 0.0 2.1e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX80389.1 - 1.7e-09 37.9 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX80389.1 - 0.0017 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORX80389.1 - 0.011 15.8 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORX80389.1 - 0.033 14.6 0.1 0.076 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PA PF02225.22 ORX80389.1 - 0.046 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 PA domain Lig_chan PF00060.26 ORX80393.1 - 0.06 13.2 0.0 0.074 12.9 0.0 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel FXR_C1 PF16096.5 ORX80399.1 - 9.9 6.4 11.2 8.1 6.7 5.6 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 PGA_cap PF09587.10 ORX80456.1 - 6.4e-59 199.5 0.0 7.9e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap RNase_PH PF01138.21 ORX80457.1 - 3.8e-24 85.7 0.0 6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORX80457.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PetG PF02529.15 ORX80458.1 - 0.066 13.1 0.2 0.066 13.1 0.2 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Amastin PF07344.11 ORX80458.1 - 0.67 9.8 10.3 0.84 9.5 9.6 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein Pkinase PF00069.25 ORX80459.1 - 1.3e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX80459.1 - 1.8e-15 57.0 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX80459.1 - 3e-08 32.9 0.1 3.8e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORX80459.1 - 0.025 13.6 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORX80459.1 - 0.033 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_6 PF13405.6 ORX80460.1 - 1.1e-11 43.7 9.2 4.6e-07 29.3 1.3 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 ORX80460.1 - 1.4e-11 43.1 14.5 5.3e-06 25.6 2.6 4.6 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 ORX80460.1 - 8.7e-10 38.9 5.6 4.9e-05 23.7 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX80460.1 - 6.9e-05 22.6 7.7 0.13 12.2 0.0 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 ORX80460.1 - 0.00021 21.5 0.5 0.92 9.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 ORX80460.1 - 0.00031 20.1 5.1 0.00041 19.7 1.6 2.8 2 1 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 ORX80460.1 - 0.036 14.9 0.1 0.086 13.7 0.1 1.6 1 1 1 2 2 2 0 EF-hand domain WSC PF01822.19 ORX80461.1 - 6.2e-17 61.6 5.6 9.8e-17 60.9 5.6 1.3 1 0 0 1 1 1 1 WSC domain PepSY_TM PF03929.16 ORX80461.1 - 0.074 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Gram_pos_anchor PF00746.21 ORX80461.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Phage_HK97_TLTM PF06120.11 ORX80461.1 - 0.19 10.9 0.1 0.27 10.4 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein RNA_pol_N PF01194.17 ORX80462.1 - 4e-33 113.5 0.5 4.6e-33 113.3 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Ribosomal_S19e PF01090.19 ORX80463.1 - 2.7e-58 195.5 0.3 3e-58 195.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e UQ_con PF00179.26 ORX80464.1 - 3.8e-35 120.6 0.0 4.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 60KD_IMP PF02096.20 ORX80465.1 - 0.011 15.6 4.9 0.011 15.6 4.9 1.7 2 0 0 2 2 2 0 60Kd inner membrane protein DUF2852 PF11014.8 ORX80466.1 - 0.097 12.8 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) NicO PF03824.16 ORX80467.1 - 2.2e-84 283.1 13.8 2.2e-84 283.1 13.8 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein MHYT PF03707.16 ORX80467.1 - 0.73 10.0 0.1 0.73 10.0 0.1 4.1 4 1 1 5 5 5 0 Bacterial signalling protein N terminal repeat COesterase PF00135.28 ORX80468.1 - 7.1e-95 318.8 0.0 9.4e-95 318.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORX80468.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORX80468.1 - 0.024 14.5 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Glyco_hydro_20 PF00728.22 ORX80469.1 - 1.6e-90 304.0 3.2 2e-90 303.7 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORX80469.1 - 1.6e-20 74.1 0.0 5.9e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORX80469.1 - 2.4e-05 25.1 0.0 8.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Candida_ALS_N PF11766.8 ORX80469.1 - 0.11 11.7 0.1 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Cell-wall agglutinin N-terminal ligand-sugar binding Epimerase PF01370.21 ORX80496.1 - 1.1e-05 25.0 0.4 0.0009 18.8 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORX80496.1 - 0.0043 16.6 1.7 0.017 14.7 0.2 2.4 2 1 1 3 3 3 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORX80496.1 - 0.015 14.7 0.2 0.057 12.8 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORX80496.1 - 0.046 13.6 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding SIS PF01380.22 ORX80496.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 SIS domain Abhydrolase_1 PF00561.20 ORX80497.1 - 2.7e-23 83.0 0.2 1.4e-21 77.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX80497.1 - 1.4e-18 68.3 0.1 1.8e-18 68.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX80497.1 - 6.5e-18 64.9 0.2 1.3e-17 63.9 0.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORX80497.1 - 2.5e-12 46.1 0.0 3.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 ORX80497.1 - 2.3e-05 24.4 0.1 6.7e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 ORX80497.1 - 0.0001 22.2 1.0 0.014 15.2 0.2 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 ORX80497.1 - 0.00011 22.3 0.0 0.00053 20.1 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Esterase PF00756.20 ORX80497.1 - 0.00089 19.0 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORX80497.1 - 0.0052 16.3 0.2 0.059 12.8 0.2 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.12 ORX80497.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.18 ORX80497.1 - 0.018 14.6 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORX80497.1 - 0.047 13.5 0.3 0.13 12.1 0.3 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 ORX80497.1 - 0.07 12.8 0.1 1.1 8.8 0.2 2.4 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Methyltransf_31 PF13847.6 ORX80498.1 - 9.7e-20 70.9 0.0 1.5e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX80498.1 - 7e-19 68.3 0.0 2.6e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX80498.1 - 2.4e-18 66.6 0.0 1.3e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX80498.1 - 3.1e-15 56.4 0.0 4.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX80498.1 - 2.1e-13 50.9 0.0 4.6e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX80498.1 - 1.5e-08 34.3 0.0 7.1e-08 32.1 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORX80498.1 - 3.6e-07 30.2 0.0 5.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 ORX80498.1 - 4.2e-06 26.2 0.0 7.9e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORX80498.1 - 9.3e-06 24.8 0.0 1.4e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 ORX80498.1 - 6.8e-05 22.9 0.0 9.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 ORX80498.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 ORX80498.1 - 0.00034 20.8 0.0 0.014 15.5 0.0 2.6 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 ORX80498.1 - 0.00076 18.8 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 ORX80498.1 - 0.0013 19.7 0.1 0.03 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORX80498.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 ORX80498.1 - 0.0072 15.9 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 CheR PF01739.18 ORX80498.1 - 0.012 15.1 0.0 0.14 11.6 0.0 2.2 2 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.26 ORX80498.1 - 0.017 15.1 0.1 0.043 13.8 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PALP PF00291.25 ORX80498.1 - 0.048 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_4 PF02390.17 ORX80498.1 - 0.11 12.0 0.0 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 ORX80499.1 - 3.4e-16 59.5 0.0 5.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX80499.1 - 4.6e-15 55.7 0.0 6.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX80499.1 - 3.2e-13 50.2 0.0 5.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX80499.1 - 1.6e-11 44.7 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX80499.1 - 2.4e-10 41.1 0.0 4.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX80499.1 - 8.3e-07 28.6 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ORX80499.1 - 0.00035 20.1 0.0 0.00064 19.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ORX80499.1 - 0.00044 19.3 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 ORX80499.1 - 0.002 18.3 0.0 0.004 17.3 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 ORX80499.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ORX80499.1 - 0.0076 16.2 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORX80499.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Pox_MCEL PF03291.16 ORX80499.1 - 0.032 13.4 0.1 0.081 12.0 0.1 1.5 1 1 0 1 1 1 0 mRNA capping enzyme PCMT PF01135.19 ORX80499.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.17 ORX80499.1 - 0.099 12.0 0.1 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Spermine/spermidine synthase domain Peptidase_M99 PF17033.5 ORX80499.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Methyltransf_23 PF13489.6 ORX80500.1 - 6.9e-16 58.5 0.0 1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX80500.1 - 4.9e-14 52.4 0.0 6.7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX80500.1 - 3.7e-13 50.0 0.0 5.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX80500.1 - 2e-11 44.3 0.0 3.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX80500.1 - 5.3e-10 39.9 0.0 8.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX80500.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ORX80500.1 - 2.7e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ORX80500.1 - 0.00029 20.5 0.0 0.00065 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX80500.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 ORX80500.1 - 0.0043 17.2 0.0 0.0054 16.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 ORX80500.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 ORX80500.1 - 0.064 12.7 0.1 1.3 8.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.17 ORX80500.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PCMT PF01135.19 ORX80500.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NOT2_3_5 PF04153.18 ORX80501.1 - 4e-32 111.0 0.3 6.5e-32 110.4 0.3 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CotH PF08757.11 ORX80502.1 - 3.1e-40 138.7 0.2 4.1e-40 138.3 0.2 1.1 1 0 0 1 1 1 1 CotH kinase protein Chitin_bind_1 PF00187.19 ORX80503.1 - 2.1e-07 31.3 16.1 4.2e-07 30.3 16.1 1.5 1 0 0 1 1 1 1 Chitin recognition protein Lipase_GDSL PF00657.22 ORX80504.1 - 2.5e-06 27.6 0.0 4.2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORX80504.1 - 5e-06 27.0 0.1 6.9e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M15_4 PF13539.6 ORX80505.1 - 0.041 14.4 0.1 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_4 PF13539.6 ORX80506.1 - 0.041 14.4 0.1 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase LPMO_10 PF03067.15 ORX80507.1 - 8.1e-05 23.4 0.1 0.00016 22.4 0.1 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX80507.1 - 0.011 15.7 0.0 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 UPF0506 PF11703.8 ORX80508.1 - 0.0008 19.7 5.7 0.001 19.4 5.7 1.2 1 0 0 1 1 1 1 UPF0506 Toxin_29 PF08116.11 ORX80508.1 - 0.0035 17.3 6.7 0.0051 16.8 6.7 1.2 1 0 0 1 1 1 1 PhTx neurotoxin family Conotoxin_I2 PF17557.2 ORX80508.1 - 0.01 15.9 9.4 0.012 15.7 9.4 1.3 1 0 0 1 1 1 0 I2-superfamily conotoxins GDP_Man_Dehyd PF16363.5 ORX80528.1 - 2e-52 178.7 0.0 2.9e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX80528.1 - 3.4e-50 170.7 0.0 4.1e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX80528.1 - 6.8e-16 58.1 0.1 7e-15 54.8 0.1 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORX80528.1 - 1.2e-14 54.2 0.1 1.6e-13 50.5 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORX80528.1 - 4.6e-09 35.8 0.0 6.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORX80528.1 - 3.2e-05 23.5 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ORX80528.1 - 4.2e-05 22.9 0.0 0.16 11.1 0.0 2.4 1 1 0 2 2 2 2 Male sterility protein KR PF08659.10 ORX80528.1 - 0.00027 20.9 0.0 0.00058 19.8 0.0 1.5 1 1 0 1 1 1 1 KR domain PCMT PF01135.19 ORX80528.1 - 0.026 14.3 0.1 4 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAD_binding_10 PF13460.6 ORX80528.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORX80528.1 - 0.11 12.7 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORX80528.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 ORX80528.1 - 0.16 11.5 0.1 0.37 10.3 0.1 1.8 2 1 0 2 2 2 0 NmrA-like family GalKase_gal_bdg PF10509.9 ORX80529.1 - 8.8e-22 76.4 0.2 3.1e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 ORX80529.1 - 5.9e-14 52.2 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ORX80529.1 - 4.2e-13 49.3 2.2 8.8e-13 48.3 2.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 ORX80530.1 - 5.3e-21 73.9 0.1 1.1e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 ORX80530.1 - 7.4e-11 42.1 1.6 1.5e-10 41.1 1.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX80530.1 - 1.4e-10 41.3 0.0 3.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_AsnC-type PF13404.6 ORX80530.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 ORX80530.1 - 0.14 12.0 0.2 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain Thioredoxin_6 PF13848.6 ORX80531.1 - 1.3e-26 93.7 0.0 8.1e-22 78.0 0.0 3.9 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin PF00085.20 ORX80531.1 - 2.5e-17 62.7 0.1 4.8e-16 58.6 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin OST3_OST6 PF04756.13 ORX80531.1 - 0.00011 21.6 0.2 0.00023 20.6 0.1 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Tropomodulin PF03250.14 ORX80531.1 - 0.0073 16.4 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Tropomodulin NTP_transferase PF00483.23 ORX80532.1 - 1.8e-53 181.7 0.0 2.5e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORX80532.1 - 1.5e-12 46.7 7.2 5.7e-11 41.7 1.9 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORX80532.1 - 1.3e-09 38.6 0.0 2.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORX80532.1 - 0.00023 20.9 1.1 0.00023 20.9 1.1 2.8 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 ORX80532.1 - 0.028 14.3 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 ORX80532.1 - 0.036 12.2 0.1 0.053 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 ORX80532.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CLASP_N PF12348.8 ORX80533.1 - 1.2e-24 87.1 0.0 1.7e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal DUF1805 PF08827.11 ORX80533.1 - 0.033 14.5 0.0 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Aldedh PF00171.22 ORX80534.1 - 1.4e-154 515.0 0.0 1.8e-154 514.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORX80534.1 - 0.0029 16.7 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) RRM_1 PF00076.22 ORX80535.1 - 1.2e-28 98.7 1.3 3.8e-14 52.2 0.4 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORX80535.1 - 1.9e-06 27.8 1.7 0.00014 21.8 0.1 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 ORX80535.1 - 9.4e-05 22.4 1.4 0.016 15.3 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 ORX80535.1 - 0.0061 16.2 0.0 0.94 9.1 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORX80535.1 - 0.017 14.7 0.1 0.041 13.5 0.1 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 ORX80535.1 - 0.024 14.5 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif DbpA PF03880.15 ORX80535.1 - 0.092 12.8 1.1 3.7 7.6 0.2 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain RBP_receptor PF14752.6 ORX80536.1 - 3.8e-19 68.7 5.2 3.8e-19 68.7 5.2 1.7 1 1 0 2 2 2 1 Retinol binding protein receptor Tetraspanin PF00335.20 ORX80537.1 - 0.0024 17.6 2.1 0.0032 17.2 2.1 1.3 1 1 0 1 1 1 1 Tetraspanin family Lactamase_B PF00753.27 ORX80538.1 - 0.0028 17.7 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-RING_2 PF13639.6 ORX80538.1 - 0.013 15.9 3.5 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 ORX80538.1 - 0.25 11.2 1.5 0.48 10.3 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 ORX80538.1 - 0.63 9.5 2.8 1.3 8.6 2.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 ORX80538.1 - 2.9 7.8 5.4 29 4.6 3.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin PF00085.20 ORX80562.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin UCR_6-4kD PF08997.10 ORX80562.1 - 0.026 14.4 0.2 0.059 13.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein TPR_14 PF13428.6 ORX80563.1 - 1.7e-15 56.4 2.7 0.068 14.0 0.0 9.3 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX80563.1 - 9.3e-15 54.9 0.1 0.0073 16.8 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX80563.1 - 2.8e-14 52.1 0.2 0.024 14.8 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX80563.1 - 1e-12 47.3 4.6 0.0078 16.0 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX80563.1 - 7.4e-11 41.3 10.1 0.024 14.8 0.2 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX80563.1 - 1.8e-10 40.5 0.0 0.051 14.0 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX80563.1 - 6e-10 39.2 0.2 0.23 11.7 0.0 5.5 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORX80563.1 - 4.9e-08 33.5 3.4 0.16 12.7 0.0 7.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX80563.1 - 2.6e-05 23.8 5.1 0.62 9.8 0.0 6.6 6 1 1 7 7 7 1 TPR repeat TPR_6 PF13174.6 ORX80563.1 - 0.0007 20.1 3.6 5.2 7.9 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX80563.1 - 0.011 15.7 2.2 89 3.5 0.0 6.3 8 0 0 8 8 6 0 Tetratricopeptide repeat LPD39 PF18858.1 ORX80563.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 TPR_10 PF13374.6 ORX80563.1 - 0.021 14.7 1.5 76 3.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SPOB_a PF14689.6 ORX80563.1 - 0.026 14.2 1.0 7.7 6.3 0.0 3.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_20 PF14561.6 ORX80563.1 - 0.041 14.2 0.3 43 4.5 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat AlaDh_PNT_C PF01262.21 ORX80564.1 - 0.07 12.4 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sortilin-Vps10 PF15902.5 ORX80565.1 - 0 1391.2 10.2 9.9e-150 499.2 2.5 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ORX80565.1 - 2.7e-128 424.9 37.3 9.4e-47 159.5 3.5 4.5 5 0 0 5 5 5 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 ORX80565.1 - 1.3e-15 54.8 61.6 2.1 8.7 0.1 17.6 17 0 0 17 17 17 9 BNR/Asp-box repeat BNR_2 PF13088.6 ORX80565.1 - 7.5e-06 25.4 2.8 1 8.6 0.0 6.7 5 2 0 5 5 5 2 BNR repeat-like domain PSII_BNR PF14870.6 ORX80565.1 - 5.2e-05 22.7 6.5 5.6 6.1 0.0 7.0 8 1 0 9 9 9 2 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 ORX80565.1 - 0.00027 20.7 10.8 2.5 8.4 0.1 7.2 7 0 0 7 7 7 2 BNR-Asp box repeat DUF4329 PF14220.6 ORX80565.1 - 0.024 14.7 0.2 5.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) UCR_UQCRX_QCR9 PF05365.12 ORX80565.1 - 0.052 13.5 0.4 22 5.1 0.1 3.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like WD40 PF00400.32 ORX80566.1 - 2e-45 151.8 28.2 5.5e-09 36.5 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX80566.1 - 2.6e-21 75.7 1.7 4.7e-06 26.8 0.1 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX80566.1 - 2.1e-13 50.3 0.0 8.2e-06 25.3 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 ORX80566.1 - 1.1e-10 41.7 0.5 7.9e-05 22.6 0.0 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX80566.1 - 0.00075 18.6 5.0 0.015 14.3 0.0 4.0 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORX80566.1 - 0.016 13.7 0.2 2.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 ORX80566.1 - 0.021 13.5 0.3 2.7 6.6 0.3 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORX80566.1 - 0.055 12.8 0.3 2.6 7.3 0.0 3.1 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 ORX80566.1 - 0.08 11.2 0.2 3.6 5.8 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 ORX80566.1 - 0.081 13.4 7.4 25 5.5 0.1 6.1 7 1 0 7 7 7 0 PQQ-like domain Peptidase_S8 PF00082.22 ORX80567.1 - 1.2e-56 192.2 1.1 1.7e-56 191.7 1.1 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORX80567.1 - 1.3e-14 54.9 0.0 4e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORX80567.1 - 2.3e-05 24.3 0.0 6.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 PA domain RPT PF13446.6 ORX80567.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein CTD_bind PF04818.13 ORX80595.1 - 5.4e-08 33.5 0.1 2.1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 ORX80595.1 - 1e-07 32.3 1.7 1e-07 32.3 1.7 2.7 4 0 0 4 4 4 1 Subunit of cleavage factor IA Pcf11 Mit_KHE1 PF10173.9 ORX80596.1 - 0.027 14.5 0.8 0.043 13.9 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1664 PF07889.12 ORX80596.1 - 0.067 13.2 0.1 0.36 10.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 ORX80596.1 - 0.17 11.7 6.5 0.23 11.3 2.4 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 ORX80596.1 - 0.48 10.5 5.0 2.3 8.3 5.3 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 ORX80596.1 - 0.72 10.4 8.5 39 4.9 8.5 3.0 1 1 0 1 1 1 0 YtxH-like protein DUF1764 PF08576.10 ORX80596.1 - 1.5 9.8 3.8 3.1 8.8 3.9 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Nup88 PF10168.9 ORX80596.1 - 2.9 5.6 5.0 12 3.6 4.9 1.7 1 1 0 1 1 1 0 Nuclear pore component ApoLp-III PF07464.11 ORX80597.1 - 0.0027 17.8 1.6 0.0056 16.8 0.8 1.6 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) PDR_assoc PF08370.11 ORX80597.1 - 0.0049 16.6 0.6 0.95 9.3 0.0 2.3 2 0 0 2 2 2 2 Plant PDR ABC transporter associated Endonuc_Holl PF10107.9 ORX80597.1 - 0.0091 15.9 0.6 0.012 15.4 0.6 1.2 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase Apolipoprotein PF01442.18 ORX80597.1 - 0.1 12.5 7.5 0.14 12.0 7.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Dak2 PF02734.17 ORX80597.1 - 2.3 8.1 7.3 28 4.6 7.3 2.2 1 1 0 1 1 1 0 DAK2 domain LEA_4 PF02987.16 ORX80597.1 - 5 7.3 13.1 5.3 7.2 2.6 3.8 3 1 0 3 3 3 0 Late embryogenesis abundant protein GARP PF16731.5 ORX80597.1 - 7 6.3 16.5 15 5.2 16.0 1.7 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma CN_hydrolase PF00795.22 ORX80598.1 - 8.9e-62 208.8 0.0 1e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PPR_2 PF13041.6 ORX80599.1 - 5.5e-67 221.8 23.2 5.8e-16 58.4 0.4 12.8 7 2 7 14 14 14 10 PPR repeat family PPR PF01535.20 ORX80599.1 - 3.6e-42 139.7 15.6 2.8e-07 30.3 0.0 13.7 14 1 0 14 14 14 8 PPR repeat PPR_3 PF13812.6 ORX80599.1 - 1.8e-37 127.2 26.7 2.5e-10 40.2 0.1 10.2 4 3 8 12 12 12 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX80599.1 - 2.6e-29 100.6 5.5 0.00051 19.7 0.0 11.1 12 0 0 12 12 12 7 PPR repeat PPR_long PF17177.4 ORX80599.1 - 2.1e-18 66.5 1.1 0.00036 19.9 0.0 5.5 1 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX80599.1 - 0.00012 22.5 14.5 0.36 11.3 1.2 6.5 5 2 1 7 7 6 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 ORX80599.1 - 0.0012 18.7 0.6 19 5.5 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat BKACE PF05853.12 ORX80599.1 - 0.0052 16.1 0.7 5.7 6.2 0.0 3.2 3 0 0 3 3 3 1 beta-keto acid cleavage enzyme TPR_15 PF13429.6 ORX80599.1 - 0.011 14.9 0.1 3.5 6.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX80599.1 - 0.018 15.1 6.2 7.4 7.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Nterm_IS4 PF13006.7 ORX80599.1 - 0.059 13.6 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal TPR_6 PF13174.6 ORX80599.1 - 0.11 13.1 1.1 38 5.2 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX80599.1 - 0.13 12.5 0.0 24 5.3 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX80599.1 - 0.15 12.3 1.0 14 6.0 0.0 3.9 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MFS_3 PF05977.13 ORX80599.1 - 0.18 10.2 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector TPR_1 PF00515.28 ORX80599.1 - 0.6 10.0 5.5 5.5 7.0 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4441 PF14536.6 ORX80599.1 - 3.5 7.8 17.3 0.98 9.6 0.5 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4441) Tenui_N PF05733.11 ORX80600.1 - 0.083 12.4 0.2 0.96 8.9 0.1 2.3 2 0 0 2 2 2 0 Tenuivirus/Phlebovirus nucleocapsid protein zf-C2H2 PF00096.26 ORX80601.1 - 5.4e-11 42.3 19.4 1.3e-06 28.5 4.2 3.2 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX80601.1 - 1.2e-08 35.1 15.8 7.7e-05 23.2 2.5 3.6 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX80601.1 - 1.7e-08 34.5 0.3 1.7e-08 34.5 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 ORX80601.1 - 4.4e-06 26.9 1.9 4.4e-06 26.9 1.9 1.9 2 0 0 2 2 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORX80601.1 - 9.1e-06 25.8 5.2 0.0085 16.4 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX80601.1 - 0.00021 21.2 4.2 0.031 14.3 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORX80601.1 - 0.00099 18.9 8.1 0.046 13.6 1.0 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX80601.1 - 0.0028 17.4 2.3 0.0028 17.4 2.3 3.1 3 0 0 3 3 3 1 C2H2-type zinc-finger domain GAGA PF09237.11 ORX80601.1 - 0.0055 16.5 5.8 0.62 9.9 0.5 3.2 1 1 1 2 2 2 2 GAGA factor zf_ZIC PF18366.1 ORX80601.1 - 0.024 14.8 0.9 3.4 7.8 0.1 2.6 1 1 1 2 2 2 0 Zic proteins zinc finger domain Zn-C2H2_12 PF18112.1 ORX80601.1 - 0.024 15.1 1.2 1.1 9.7 0.2 3.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2256 PF10013.9 ORX80601.1 - 0.037 14.2 1.7 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DZR PF12773.7 ORX80601.1 - 0.043 13.8 1.2 0.15 12.1 1.2 2.0 1 0 0 1 1 1 0 Double zinc ribbon TRAF6_Z2 PF18048.1 ORX80601.1 - 0.061 13.4 0.5 5.2 7.3 0.1 2.9 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_9 PF14369.6 ORX80601.1 - 0.063 13.6 4.2 0.58 10.5 0.6 3.0 2 0 0 2 2 2 0 zinc-ribbon Rad50_zn_hook PF04423.14 ORX80601.1 - 0.071 13.0 3.9 0.34 10.8 0.4 2.6 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-met PF12874.7 ORX80601.1 - 0.093 13.2 7.8 0.16 12.4 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CHCC PF10276.9 ORX80601.1 - 0.12 12.5 1.0 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger domain DUF2225 PF09986.9 ORX80601.1 - 0.21 11.3 1.7 1 9.1 1.6 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_2 PF12756.7 ORX80601.1 - 0.25 11.7 0.2 0.25 11.7 0.2 3.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 ORX80601.1 - 1 9.2 8.7 0.16 11.7 1.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 ORX80601.1 - 1.5 8.9 7.9 2 8.5 0.6 2.7 1 1 1 2 2 2 0 BED zinc finger ERG4_ERG24 PF01222.17 ORX80602.1 - 2.4e-91 306.6 23.0 3e-91 306.3 23.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORX80602.1 - 0.015 14.8 0.7 0.039 13.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Hexapep_loop PF18776.1 ORX80634.1 - 0.017 14.7 3.0 0.032 13.8 3.0 1.4 1 0 0 1 1 1 0 Hexapeptide repeat including loop TcfC PF16967.5 ORX80634.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 E-set like domain ABC_membrane PF00664.23 ORX80635.1 - 6.8e-130 432.6 29.6 5.9e-66 222.9 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX80635.1 - 2e-73 245.4 0.1 7.1e-36 123.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX80635.1 - 4.7e-17 62.2 4.3 3.7e-06 26.5 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORX80635.1 - 9.9e-09 35.4 0.0 0.013 15.3 0.0 3.9 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 ORX80635.1 - 3.3e-08 32.8 0.3 0.00054 18.9 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORX80635.1 - 9.7e-08 32.4 0.3 0.04 14.2 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORX80635.1 - 1.7e-07 31.7 0.7 0.021 15.2 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORX80635.1 - 3.3e-07 30.4 0.0 0.0041 17.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 ORX80635.1 - 2.3e-06 28.1 0.2 10 6.5 0.0 4.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORX80635.1 - 2.9e-06 26.9 6.5 0.0022 17.7 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ORX80635.1 - 1.4e-05 24.9 0.8 0.28 10.9 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORX80635.1 - 1.5e-05 25.5 0.0 0.046 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORX80635.1 - 2.1e-05 24.4 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 ORX80635.1 - 6.5e-05 22.9 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 ORX80635.1 - 7.6e-05 22.7 0.5 0.43 10.6 0.0 3.6 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORX80635.1 - 0.00018 21.1 0.0 0.098 12.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 ORX80635.1 - 0.00037 21.0 0.1 0.3 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORX80635.1 - 0.00059 19.5 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORX80635.1 - 0.00072 19.7 2.8 0.48 10.7 0.4 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORX80635.1 - 0.0008 19.6 0.4 1.6 8.9 0.0 3.0 4 0 0 4 4 2 2 AAA domain APS_kinase PF01583.20 ORX80635.1 - 0.0024 17.8 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 ORX80635.1 - 0.0031 16.8 0.0 3.4 6.9 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 ORX80635.1 - 0.016 15.6 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 ORX80635.1 - 0.017 15.2 0.0 3.1 7.9 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORX80635.1 - 0.017 14.8 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX80635.1 - 0.018 15.3 0.0 4 7.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 ORX80635.1 - 0.018 14.2 0.0 0.29 10.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Cytidylate_kin PF02224.18 ORX80635.1 - 0.023 14.4 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 ORX80635.1 - 0.034 14.6 0.1 16 6.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 ORX80635.1 - 0.035 13.3 0.1 3.4 6.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 ORX80635.1 - 0.046 13.5 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad52_Rad22 PF04098.15 ORX80635.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein CobD_Cbib PF03186.13 ORX80635.1 - 0.063 12.5 3.5 0.073 12.3 0.3 2.4 2 0 0 2 2 2 0 CobD/Cbib protein Mg_chelatase PF01078.21 ORX80635.1 - 0.078 12.4 0.2 3.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 ORX80635.1 - 0.12 12.2 0.0 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 ORX80635.1 - 0.13 12.3 0.0 33 4.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 ORX80635.1 - 0.17 11.6 1.3 6.5 6.4 0.0 3.1 4 0 0 4 4 4 0 IstB-like ATP binding protein Halogen_Hydrol PF10112.9 ORX80635.1 - 1.1 9.2 4.8 5.8 6.9 0.3 2.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ribosomal_S8e PF01201.22 ORX80636.1 - 1.2e-49 168.1 4.8 2.8e-49 166.8 4.8 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e VIR_N PF15912.5 ORX80636.1 - 9.7 5.7 6.6 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Phos_pyr_kin PF08543.12 ORX80637.1 - 1e-22 80.7 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ORX80637.1 - 1.2e-08 34.6 0.1 4.3e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PPR_3 PF13812.6 ORX80637.1 - 0.001 19.1 0.1 0.0032 17.5 0.1 1.8 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Carb_kinase PF01256.17 ORX80637.1 - 0.018 14.5 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate kinase CODH_A_N PF18537.1 ORX80637.1 - 0.056 13.5 0.3 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain BTB PF00651.31 ORX80638.1 - 5.3e-06 26.6 0.0 7.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4268 PF14088.6 ORX80638.1 - 0.042 13.7 0.1 0.06 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4268) DUF5425 PF17472.2 ORX80638.1 - 0.043 14.6 0.2 0.07 13.9 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5425) Ndc80_HEC PF03801.13 ORX80638.1 - 0.059 13.0 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family Pribosyl_synth PF14572.6 ORX80668.1 - 4.3e-48 163.8 2.8 6.5e-38 130.6 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORX80668.1 - 6.3e-48 161.5 0.3 1.5e-46 157.1 0.1 2.6 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORX80668.1 - 8.3e-15 54.6 2.3 2.5e-13 49.8 0.9 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Mcp5_PH PF12814.7 ORX80669.1 - 6.6e-33 113.4 0.4 2.1e-32 111.8 0.4 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TACC_C PF05010.14 ORX80669.1 - 0.23 11.3 20.2 0.13 12.0 0.3 3.4 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Latarcin PF10279.9 ORX80669.1 - 2.2 8.8 6.3 17 5.9 5.0 3.1 3 0 0 3 3 3 0 Latarcin precursor PKcGMP_CC PF16808.5 ORX80669.1 - 2.4 8.1 11.1 1.4 8.8 0.1 3.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DnaJ PF00226.31 ORX80670.1 - 2e-20 72.7 0.6 4.4e-20 71.6 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 ORX80671.1 - 9.3e-70 235.0 0.0 1.5e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX80671.1 - 3.4e-50 170.7 0.0 5.3e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ORX80671.1 - 3.8e-19 68.9 0.0 8.1e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 ORX80671.1 - 2.8e-16 59.7 0.1 5e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORX80671.1 - 4.5e-12 45.9 0.5 1.1e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 ORX80671.1 - 6.8e-08 33.0 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 ORX80671.1 - 0.00013 21.4 0.0 0.00036 19.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like SAM_PNT PF02198.16 ORX80671.1 - 0.00052 19.9 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 ORX80671.1 - 0.0024 16.7 0.0 0.0045 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 ORX80671.1 - 0.0056 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 ORX80671.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 ORX80671.1 - 0.031 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORX80671.1 - 0.24 11.3 0.2 3.1 7.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Longin PF13774.6 ORX80672.1 - 1.3e-15 57.2 0.0 2.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ORX80672.1 - 2.9e-14 52.6 0.6 4.9e-14 51.9 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Herpes_teg_N PF04843.12 ORX80672.1 - 0.083 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Amidase PF01425.21 ORX80673.1 - 6e-54 183.7 2.1 7.1e-54 183.5 2.1 1.1 1 0 0 1 1 1 1 Amidase RHS PF03527.14 ORX80673.1 - 0.096 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 RHS protein MFS_1 PF07690.16 ORX80674.1 - 1.8e-51 175.1 28.5 1.8e-51 175.1 28.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX80674.1 - 2.5e-12 46.4 11.4 2.5e-12 46.4 11.4 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1269 PF06897.12 ORX80674.1 - 0.051 13.9 0.8 6.4 7.1 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Gti1_Pac2 PF09729.9 ORX80675.1 - 3.6e-47 160.8 2.6 6.1e-41 140.5 0.2 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Glyco_hydro_9 PF00759.19 ORX80676.1 - 3.4e-82 277.1 0.1 3.7e-82 276.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 LPMO_10 PF03067.15 ORX80677.1 - 0.00071 20.3 0.2 0.0048 17.6 0.2 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX80677.1 - 0.013 15.5 0.0 0.47 10.3 0.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 GPI-anchored PF10342.9 ORX80677.1 - 0.043 14.6 0.0 0.071 13.9 0.0 1.4 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DSL PF01414.19 ORX80702.1 - 0.02 15.1 3.4 0.032 14.5 3.4 1.3 1 0 0 1 1 1 0 Delta serrate ligand DJ-1_PfpI PF01965.24 ORX80703.1 - 7.3e-09 35.6 0.0 2.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX80703.1 - 0.0016 18.2 0.1 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX80703.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain Myticin-prepro PF10690.9 ORX80708.1 - 0.0041 17.3 0.5 0.0064 16.7 0.5 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Myticin-prepro PF10690.9 ORX80710.1 - 0.0037 17.5 0.6 0.008 16.4 0.6 1.6 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Abhydrolase_1 PF00561.20 ORX80710.1 - 0.069 12.8 0.1 0.076 12.6 0.1 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Myticin-prepro PF10690.9 ORX80713.1 - 0.027 14.7 0.2 0.027 14.7 0.2 2.0 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel tRNA-synt_2d PF01409.20 ORX80740.1 - 7.4e-93 310.5 0.1 1e-92 310.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ORX80740.1 - 2.6e-19 69.2 1.1 2.6e-19 69.2 1.1 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 ORX80740.1 - 7.7e-09 35.3 0.0 8.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 ORX80740.1 - 2.1e-05 23.8 0.1 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 ORX80740.1 - 0.00047 20.2 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD1 PF18552.1 ORX80740.1 - 0.011 15.5 0.6 0.037 13.8 0.3 2.1 2 0 0 2 2 2 0 PheRS DNA binding domain 1 S10_plectin PF03501.15 ORX80740.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Plectin/S10 domain Pkinase PF00069.25 ORX80741.1 - 3.4e-71 239.7 0.0 5.5e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX80741.1 - 8e-33 113.8 0.0 1.4e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX80741.1 - 0.0022 17.4 0.5 2.1 7.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 ORX80741.1 - 0.035 12.9 0.0 0.063 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Gp_dh_C PF02800.20 ORX80742.1 - 1.7e-71 238.9 0.0 2.8e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORX80742.1 - 4.6e-40 136.0 0.1 9.3e-40 135.1 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX80742.1 - 0.013 15.6 0.1 0.075 13.2 0.0 2.3 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Wbp11 PF09429.10 ORX80743.1 - 0.14 12.5 15.9 0.29 11.6 5.9 3.2 2 1 1 3 3 3 0 WW domain binding protein 11 NPV_P10 PF05531.12 ORX80743.1 - 0.45 11.0 7.2 24 5.5 0.1 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 ORX80743.1 - 1.3 9.0 18.0 1.5 8.8 4.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4061 PF13270.6 ORX80745.1 - 1.7e-09 37.8 1.7 2.5e-09 37.3 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) BLOC1_2 PF10046.9 ORX80745.1 - 0.012 15.8 0.8 0.019 15.3 0.3 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMEM70 PF06979.12 ORX80746.1 - 8.3e-05 23.0 1.1 0.00015 22.2 1.1 1.4 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Ribosomal_L32e PF01655.18 ORX80747.1 - 3.1e-54 182.0 2.3 3.1e-54 182.0 2.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 Ribosomal_S9 PF00380.19 ORX80748.1 - 6e-34 117.2 0.2 6.8e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MOSC PF03473.17 ORX80749.1 - 2e-32 112.0 0.0 4.1e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 ORX80749.1 - 2.5e-24 85.9 0.0 6.7e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 ORX80749.1 - 3.4e-19 68.9 0.0 7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain XAF1_C PF18608.1 ORX80749.1 - 0.066 12.8 0.1 19 4.9 0.0 2.7 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain Mem_trans PF03547.18 ORX80750.1 - 3.6e-26 91.5 14.9 6.4e-26 90.7 14.9 1.4 1 1 0 1 1 1 1 Membrane transport protein HTH_23 PF13384.6 ORX80751.1 - 0.016 15.0 0.1 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain CNOT11 PF10155.9 ORX80751.1 - 0.03 14.5 0.8 0.086 13.0 0.3 2.0 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Ribosomal_L18_c PF14204.6 ORX80751.1 - 0.11 13.5 0.2 0.46 11.4 0.2 2.0 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region COX_ARM PF06481.14 ORX80751.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 COX Aromatic Rich Motif PALP PF00291.25 ORX80804.1 - 1.2e-63 215.3 0.0 1.4e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4246 PF14033.6 ORX80805.1 - 2.1e-140 468.8 0.0 2.4e-140 468.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) LAT PF15234.6 ORX80805.1 - 0.086 12.6 1.0 0.14 11.9 1.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells 2OG-Fe_Oxy_2 PF10014.9 ORX80805.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase LEA_2 PF03168.13 ORX80806.1 - 0.14 12.7 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Ribosomal_S2 PF00318.20 ORX80809.1 - 6.9e-28 97.4 0.8 8.9e-15 54.5 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORX80809.1 - 1.3e-07 32.9 18.5 2.5e-07 32.0 18.5 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus LSM PF01423.22 ORX80810.1 - 2.3e-18 65.6 0.2 3e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Propep_M14 PF02244.16 ORX80810.1 - 0.085 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Hfq PF17209.3 ORX80810.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein ATP-synt_Eps PF04627.13 ORX80811.1 - 2.3e-22 78.7 3.1 2.7e-22 78.5 3.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ribosomal_L14 PF00238.19 ORX80812.1 - 3.3e-35 120.8 0.1 4e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Clat_adaptor_s PF01217.20 ORX80813.1 - 4.9e-50 169.2 2.9 5.7e-50 168.9 2.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MitMem_reg PF13012.6 ORX80814.1 - 2.7e-39 134.1 1.7 4.8e-39 133.3 1.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORX80814.1 - 2.4e-31 108.2 0.0 5.9e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0020 PF01170.18 ORX80815.1 - 1.6e-25 90.0 0.0 8.9e-25 87.5 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 ORX80815.1 - 6.9e-05 23.5 0.0 0.00016 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 ORX80815.1 - 0.0017 17.8 0.1 0.033 13.6 0.0 2.1 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 ORX80815.1 - 0.0021 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ORX80815.1 - 0.0056 17.3 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain THUMP PF02926.17 ORX80815.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 THUMP domain Methyltransf_4 PF02390.17 ORX80815.1 - 0.027 13.9 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 ORX80815.1 - 0.038 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CUE PF02845.16 ORX80815.1 - 0.12 12.1 0.1 7.2 6.4 0.0 2.8 2 0 0 2 2 2 0 CUE domain FYVE PF01363.21 ORX80816.1 - 8.1e-18 64.3 13.9 1.2e-17 63.8 13.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 ORX80816.1 - 0.21 11.8 8.3 0.33 11.2 8.3 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Fer4_21 PF14697.6 ORX80816.1 - 0.35 11.0 7.0 0.93 9.7 5.5 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-ribbon_3 PF13248.6 ORX80816.1 - 0.98 8.9 0.1 0.98 8.9 0.1 3.5 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 ORX80816.1 - 1.1 9.4 12.7 1.1e+02 2.9 12.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ORX80816.1 - 1.4 9.0 9.3 2.4 8.2 3.4 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fer4_9 PF13187.6 ORX80816.1 - 2.2 8.5 9.8 3.1 8.0 7.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain IBR PF01485.21 ORX80816.1 - 6.6 7.0 14.7 0.46 10.8 8.8 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain RibD_C PF01872.17 ORX80817.1 - 2.5e-07 30.7 0.0 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain F-box-like PF12937.7 ORX80818.1 - 7.8e-07 28.9 0.4 1.7e-06 27.8 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX80818.1 - 0.00074 19.3 0.6 0.0028 17.5 0.2 2.2 2 0 0 2 2 2 1 F-box domain ECH_2 PF16113.5 ORX80819.1 - 1.3e-129 432.5 0.0 1.6e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORX80819.1 - 2.4e-31 108.9 0.0 2e-29 102.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Mitovir_RNA_pol PF05919.11 ORX80819.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase CAP PF00188.26 ORX80848.1 - 9.9e-17 62.0 0.1 1.3e-16 61.6 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Uds1 PF15456.6 ORX80849.1 - 4.8e-16 59.1 5.3 4.8e-16 59.1 5.3 4.0 2 1 2 4 4 4 1 Up-regulated During Septation HR1 PF02185.16 ORX80849.1 - 3.9e-09 36.5 2.7 3.9e-09 36.5 2.7 3.2 3 1 0 3 3 3 1 Hr1 repeat DUF2408 PF10303.9 ORX80849.1 - 2.2 8.8 16.7 0.097 13.2 7.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) FliL PF03748.14 ORX80849.1 - 5.9 7.5 9.1 3.9 8.1 2.9 2.8 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL Tom7 PF08038.12 ORX80851.1 - 8.5e-17 60.5 0.3 9.5e-17 60.4 0.3 1.0 1 0 0 1 1 1 1 TOM7 family GPI-anchored PF10342.9 ORX80852.1 - 7.7e-12 45.8 0.0 1.2e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bromodomain PF00439.25 ORX80853.1 - 4.9e-24 84.2 0.3 1e-23 83.2 0.3 1.6 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 ORX80853.1 - 1.2e-12 47.9 0.0 2.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) GATA PF00320.27 ORX80853.1 - 1.2e-12 47.2 4.2 2.6e-12 46.1 4.2 1.6 1 0 0 1 1 1 1 GATA zinc finger Arf PF00025.21 ORX80854.1 - 8.5e-80 266.3 0.1 9.7e-80 266.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX80854.1 - 2e-14 53.4 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORX80854.1 - 2.6e-14 53.5 0.0 3.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORX80854.1 - 3.1e-13 49.6 1.5 1.8e-09 37.2 0.5 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORX80854.1 - 5.2e-13 48.9 0.0 6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX80854.1 - 1.2e-10 41.2 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX80854.1 - 1.8e-06 28.0 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX80854.1 - 0.007 15.7 0.7 0.019 14.3 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Uds1 PF15456.6 ORX80855.1 - 1.6e-09 38.0 1.2 1.6e-09 38.0 1.2 4.8 3 2 2 5 5 5 1 Up-regulated During Septation HR1 PF02185.16 ORX80855.1 - 0.00013 22.1 0.4 0.00013 22.1 0.4 4.3 5 0 0 5 5 5 2 Hr1 repeat Alpha-2-MRAP_C PF06401.11 ORX80855.1 - 0.0035 17.4 4.6 0.0035 17.4 4.6 2.9 2 2 2 4 4 4 1 Alpha-2-macroglobulin RAP, C-terminal domain DUF1192 PF06698.11 ORX80855.1 - 0.031 14.3 5.2 10 6.3 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DUF5320 PF17253.2 ORX80855.1 - 0.065 14.3 5.3 3.9 8.6 0.1 3.6 3 2 0 3 3 3 0 Family of unknown function (DUF5320) YgaB PF14182.6 ORX80855.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.9 5 0 0 5 5 4 0 YgaB-like protein Lipoprotein_2 PF00921.17 ORX80855.1 - 0.22 11.0 2.4 0.21 11.1 0.9 1.7 2 0 0 2 2 2 0 Borrelia lipoprotein DUF948 PF06103.11 ORX80855.1 - 0.28 11.5 3.6 31 4.9 0.2 3.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2716 PF10898.8 ORX80855.1 - 0.34 11.3 2.4 1.3 9.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) FAM76 PF16046.5 ORX80855.1 - 0.53 9.6 12.0 1 8.6 11.6 1.8 1 1 0 1 1 1 0 FAM76 protein DUF4200 PF13863.6 ORX80855.1 - 0.63 10.5 0.1 0.63 10.5 0.1 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4200) PRKG1_interact PF15898.5 ORX80855.1 - 1.2 10.0 24.9 1.5 9.8 1.0 4.2 2 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 ORX80855.1 - 1.4 9.6 19.3 18 6.0 4.0 4.8 2 2 3 5 5 5 0 Initiation control protein YabA LPP PF04728.13 ORX80855.1 - 1.4 9.3 12.6 1.8 9.0 0.3 4.9 6 0 0 6 6 6 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 ORX80855.1 - 2.4 7.4 15.8 0.077 12.3 5.7 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 ORX80855.1 - 5.1 7.6 18.4 7.1 7.1 0.1 4.9 5 1 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.12 ORX80855.1 - 6.3 7.2 19.3 8.2 6.9 0.3 4.3 2 1 1 4 4 4 0 Centromere protein H (CENP-H) TSC22 PF01166.18 ORX80855.1 - 9.7 6.6 21.0 2.6 8.4 0.2 5.1 5 0 0 5 5 5 0 TSC-22/dip/bun family Xan_ur_permease PF00860.20 ORX80856.1 - 2.3e-49 168.1 31.9 1e-47 162.7 31.9 2.2 1 1 0 1 1 1 1 Permease family dCMP_cyt_deam_1 PF00383.23 ORX80857.1 - 2.7e-14 52.8 0.0 4.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX80857.1 - 9.7e-07 28.6 0.0 5.2e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORX80857.1 - 0.0002 21.5 0.5 0.00082 19.5 0.5 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase Inv-AAD PF18785.1 ORX80857.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORX80858.1 - 1.1e-12 47.7 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX80858.1 - 6.4e-07 29.2 0.0 3.1e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORX80858.1 - 0.00011 22.2 0.5 0.00048 20.2 0.5 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase Inv-AAD PF18785.1 ORX80858.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORX80859.1 - 5.3e-14 51.9 0.0 7.7e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX80859.1 - 1e-06 28.5 0.0 5e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORX80859.1 - 0.00017 21.6 0.4 0.0007 19.7 0.4 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase Inv-AAD PF18785.1 ORX80859.1 - 0.0093 15.8 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase HPP PF04982.13 ORX80887.1 - 3.3e-37 127.4 8.5 4.4e-37 127.0 6.6 1.9 2 0 0 2 2 2 1 HPP family GAIN_A PF18619.1 ORX80887.1 - 0.34 11.1 0.2 0.34 11.1 0.2 2.1 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF5345 PF17280.2 ORX80887.1 - 0.75 9.8 4.6 3.2 7.8 0.5 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Bax1-I PF01027.20 ORX80887.1 - 3.8 7.3 16.1 7.6 6.3 16.1 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 GFO_IDH_MocA PF01408.22 ORX80913.1 - 2.7e-14 54.0 0.0 4.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX80913.1 - 2.5e-07 30.7 0.0 7.5e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GPHH PF16905.5 ORX80945.1 - 0.0015 18.3 0.3 39 4.1 0.0 4.8 6 0 0 6 6 6 3 Voltage-dependent L-type calcium channel, IQ-associated GPHH PF16905.5 ORX80946.1 - 4.1e-08 32.9 1.0 89 3.0 0.0 9.4 11 0 0 11 11 11 6 Voltage-dependent L-type calcium channel, IQ-associated Mito_carr PF00153.27 ORX80948.1 - 1.2e-63 211.1 2.9 1e-23 83.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LysE PF01810.18 ORX80948.1 - 0.011 15.2 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 LysE type translocator NAD_binding_10 PF13460.6 ORX80950.1 - 2.9e-14 53.4 0.0 4.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX80950.1 - 9.1e-12 44.9 0.0 5.7e-11 42.3 0.0 2.2 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORX80950.1 - 2.7e-11 43.5 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 ORX80950.1 - 1.9e-10 40.3 0.0 6.8e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX80950.1 - 1.3e-08 34.2 0.0 2.1e-07 30.2 0.0 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX80950.1 - 4.8e-05 22.7 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ORX80950.1 - 0.00014 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORX80950.1 - 0.0045 16.5 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ORX80950.1 - 0.19 10.8 0.0 0.51 9.4 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 ORX80950.1 - 0.23 11.0 0.0 0.55 9.8 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 ORX80951.1 - 1.3e-87 293.0 0.1 1.6e-87 292.7 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORX80951.1 - 6.6e-18 65.2 0.0 1.8e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX80951.1 - 7.8e-18 64.9 0.0 3.9e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX80951.1 - 1e-14 54.6 0.0 3.9e-14 52.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX80951.1 - 4.8e-12 46.5 0.0 8.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX80951.1 - 3.2e-11 43.3 0.0 4.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 ORX80951.1 - 9.1e-05 22.5 0.0 0.00027 20.9 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase MTS PF05175.14 ORX80951.1 - 0.0037 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORX80951.1 - 0.0065 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 ORX80951.1 - 0.012 16.7 0.0 0.029 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 ORX80951.1 - 0.025 14.2 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 ORX80951.1 - 0.027 14.3 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_5 PF01795.19 ORX80951.1 - 0.17 11.4 0.0 3.1 7.2 0.0 2.0 1 1 1 2 2 2 0 MraW methylase family Peptidase_C48 PF02902.19 ORX80952.1 - 1.4e-48 165.6 6.1 2.3e-48 164.9 6.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 ORX80952.1 - 1.2e-05 24.3 5.3 0.00014 20.7 0.9 2.2 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase Nucleoporin_N PF08801.11 ORX80953.1 - 2.9e-83 280.1 0.3 4.8e-83 279.3 0.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORX80953.1 - 4.8e-41 141.2 4.0 5.5e-40 137.7 4.0 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Fungal_lectin PF07938.12 ORX80953.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Fungal fucose-specific lectin Complex1_LYR PF05347.15 ORX80954.1 - 6.8e-06 26.0 0.2 1.3e-05 25.1 0.2 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) T6SS_VipA PF05591.12 ORX80954.1 - 0.0024 17.7 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Complex1_LYR_2 PF13233.6 ORX80954.1 - 0.0045 17.7 0.1 0.0074 17.0 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORX80954.1 - 0.033 14.8 0.1 0.056 14.0 0.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like TMEM141 PF15110.6 ORX80955.1 - 6.5e-05 23.4 0.0 9.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 TMEM141 protein family EutH PF04346.12 ORX80955.1 - 0.041 13.1 0.0 0.05 12.8 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH CytB6-F_Fe-S PF08802.10 ORX80955.1 - 0.062 13.3 0.2 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Coiled-coil_56 PF09813.9 ORX80955.1 - 0.15 12.1 0.1 0.7 10.0 0.0 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Trefoil PF00088.18 ORX80956.1 - 1.8e-17 63.0 29.1 1.7e-05 24.6 2.5 4.2 4 0 0 4 4 4 4 Trefoil (P-type) domain DUF202 PF02656.15 ORX80957.1 - 5e-23 81.3 0.5 5e-23 81.3 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cation_ATPase_C PF00689.21 ORX80957.1 - 0.016 15.0 1.3 0.021 14.6 1.3 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus YtpI PF14007.6 ORX80957.1 - 0.071 13.2 2.6 0.18 12.0 2.0 1.9 2 0 0 2 2 2 0 YtpI-like protein NDUF_B4 PF07225.12 ORX80957.1 - 0.078 12.9 1.0 0.17 11.8 0.1 1.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2207 PF09972.9 ORX80957.1 - 9.3 4.9 5.4 8 5.1 4.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Catalase PF00199.19 ORX80958.1 - 1.6e-202 672.7 2.4 1.9e-202 672.4 2.4 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORX80958.1 - 4.1e-20 71.8 0.0 9.2e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Cellulase PF00150.18 ORX80986.1 - 4.9e-10 39.3 0.7 1.4e-09 37.8 0.7 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S3Ae PF01015.18 ORX80989.1 - 5.4e-94 313.4 1.4 6.7e-94 313.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 ORX80989.1 - 0.027 15.0 0.2 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 ORX80989.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Rep_fac_C PF08542.11 ORX80990.1 - 9.8e-25 86.8 0.0 3.3e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORX80990.1 - 7.5e-13 48.6 0.0 5.1e-10 39.4 0.2 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 ORX80990.1 - 1.8e-12 47.8 0.0 3.3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORX80990.1 - 4.2e-07 30.0 0.0 8.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX80990.1 - 4.5e-06 27.2 0.0 0.00041 20.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 ORX80990.1 - 1.3e-05 24.7 0.0 0.00019 20.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORX80990.1 - 1.8e-05 25.0 0.0 0.023 15.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORX80990.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 ORX80990.1 - 2.9e-05 23.9 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 ORX80990.1 - 0.0012 18.6 0.0 0.0037 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORX80990.1 - 0.0025 17.6 0.0 0.0063 16.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 ORX80990.1 - 0.0026 17.6 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ORX80990.1 - 0.0047 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORX80990.1 - 0.0098 16.2 0.2 0.041 14.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORX80990.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ORX80990.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 ORX80990.1 - 0.014 14.8 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein DNA_pol3_delta PF06144.13 ORX80990.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 ORX80990.1 - 0.027 14.8 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 ORX80990.1 - 0.052 13.5 0.4 0.21 11.5 0.2 2.0 1 1 1 2 2 2 0 NTPase DUF5119 PF17145.4 ORX80990.1 - 0.074 13.0 0.0 8.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) MeaB PF03308.16 ORX80990.1 - 0.078 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ORX80990.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 ORX80990.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ CBP4 PF07960.11 ORX80991.1 - 5.2e-18 65.2 0.1 5.2e-18 65.1 0.1 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 ORX80991.1 - 4e-06 26.7 0.0 4.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF3810 PF12725.7 ORX80991.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ABC_tran PF00005.27 ORX80992.1 - 7.6e-31 107.4 0.0 1.1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX80992.1 - 1e-15 58.3 1.1 1.3e-09 38.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORX80992.1 - 2.9e-13 49.7 22.3 3.7e-13 49.3 22.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 ORX80992.1 - 0.0014 19.1 0.1 0.0024 18.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORX80992.1 - 0.008 15.6 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX80992.1 - 0.022 14.5 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 ORX80992.1 - 0.028 14.2 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 ORX80992.1 - 0.032 14.5 0.0 0.32 11.2 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ORX80992.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORX80992.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DLIC PF05783.11 ORX80992.1 - 0.27 10.0 0.0 0.42 9.4 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ribosomal_L36e PF01158.18 ORX80993.1 - 1.7e-41 140.4 7.1 1.9e-41 140.2 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mago-bind PF09282.10 ORX80993.1 - 0.22 11.4 1.7 7.4 6.5 0.2 2.7 2 0 0 2 2 2 0 Mago binding Methyltransf_3 PF01596.17 ORX80995.1 - 1.1e-40 139.1 0.0 1.3e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX80995.1 - 8.5e-15 55.7 0.0 2.1e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX80995.1 - 0.00043 20.0 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 ORX80995.1 - 0.00049 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L36e PF01158.18 ORX80996.1 - 1.7e-41 140.4 7.1 1.9e-41 140.2 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mago-bind PF09282.10 ORX80996.1 - 0.22 11.4 1.7 7.4 6.5 0.2 2.7 2 0 0 2 2 2 0 Mago binding Aminotran_5 PF00266.19 ORX80997.1 - 7.6e-33 114.0 0.0 1.2e-31 110.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 ORX80997.1 - 0.0062 15.3 0.0 0.074 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain MFS_1 PF07690.16 ORX80998.1 - 1.6e-22 79.9 35.3 2.5e-14 53.0 12.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 ORX80999.1 - 1.8e-29 102.2 1.8 3.5e-29 101.3 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX80999.1 - 2.6e-16 59.4 5.4 2.6e-16 59.4 5.4 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 ORX80999.1 - 0.012 15.0 0.2 0.02 14.3 0.2 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF3839 PF12943.7 ORX80999.1 - 0.067 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) Ribonuclease_T2 PF00445.18 ORX81000.1 - 9.4e-37 127.0 0.0 1.4e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family HAD_2 PF13419.6 ORX81024.1 - 3.8e-27 95.5 0.0 5.4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX81024.1 - 1.1e-16 61.8 0.0 2.4e-14 54.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX81024.1 - 1.2e-06 28.5 0.0 3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORX81024.1 - 0.005 17.3 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BET PF17035.5 ORX81024.1 - 0.026 14.7 0.2 0.05 13.8 0.2 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Dicty_CAR PF05462.11 ORX81025.1 - 1.6e-19 70.2 3.8 2.1e-19 69.8 3.8 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORX81025.1 - 0.00094 18.6 0.4 0.0019 17.5 0.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIG-14_Wnt-bd PF06664.12 ORX81025.1 - 0.0067 15.7 1.4 0.0091 15.3 1.4 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Frizzled PF01534.17 ORX81025.1 - 0.0068 15.5 0.3 0.009 15.1 0.2 1.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Cation_ATPase_C PF00689.21 ORX81025.1 - 1.4 8.6 7.5 14 5.3 3.3 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus MAP17 PF15807.5 ORX81025.1 - 2.7 8.2 3.8 2.9 8.2 0.0 2.3 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FMO-like PF00743.19 ORX81026.1 - 5.3e-90 302.3 0.0 7.4e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORX81026.1 - 3.9e-12 46.1 0.1 4.4e-09 36.0 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX81026.1 - 3.2e-09 36.4 0.0 5.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX81026.1 - 1.1e-05 24.8 0.1 0.00069 18.9 0.0 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 ORX81026.1 - 7.7e-05 23.2 0.1 0.00041 20.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX81026.1 - 0.00074 19.5 0.0 1.6 8.7 0.0 4.1 5 0 0 5 5 5 1 FAD-NAD(P)-binding DAO PF01266.24 ORX81026.1 - 0.017 14.7 0.0 9.1 5.7 0.1 3.0 2 1 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ORX81026.1 - 0.029 14.4 0.1 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CBM_20 PF00686.19 ORX81026.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Starch binding domain 5_nucleotid_C PF02872.18 ORX81060.1 - 8.3e-24 84.6 0.0 1.5e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORX81060.1 - 1.2e-12 48.8 0.3 2.5e-12 47.8 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosom_S12_S23 PF00164.25 ORX81061.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IATP PF04568.12 ORX81062.1 - 3.6e-14 53.0 1.5 4.1e-14 52.8 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FAP206 PF12018.8 ORX81062.1 - 0.0017 17.9 0.4 0.0017 17.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function Rx_N PF18052.1 ORX81062.1 - 0.038 14.3 0.9 0.047 14.0 0.9 1.2 1 0 0 1 1 1 0 Rx N-terminal domain DUF4140 PF13600.6 ORX81062.1 - 0.07 13.6 1.3 0.079 13.4 1.3 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ApoO PF09769.9 ORX81062.1 - 0.11 12.5 1.5 6.8 6.7 0.7 2.0 1 1 1 2 2 2 0 Apolipoprotein O YgaB PF14182.6 ORX81062.1 - 0.13 12.7 4.7 0.17 12.3 4.7 1.2 1 0 0 1 1 1 0 YgaB-like protein DUF1043 PF06295.12 ORX81062.1 - 0.33 11.0 7.9 0.24 11.4 6.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Pkinase PF00069.25 ORX81063.1 - 5.7e-06 25.9 0.0 6.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORX81064.1 - 4e-28 98.5 1.2 5.5e-28 98.1 1.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX81064.1 - 5.8e-18 65.1 0.2 8e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX81064.1 - 0.00046 20.2 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX81064.1 - 0.0035 17.0 0.4 0.0065 16.1 0.4 1.5 1 0 0 1 1 1 1 RIO1 family ABC1 PF03109.16 ORX81064.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Kinase-like PF14531.6 ORX81064.1 - 0.045 13.1 0.2 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 ORX81064.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX81064.1 - 0.11 12.2 0.5 9.1 5.8 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Methyltransf_11 PF08241.12 ORX81067.1 - 3.1e-20 72.6 0.1 6.5e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX81067.1 - 6.5e-19 68.4 0.0 1.5e-17 64.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX81067.1 - 2.1e-17 63.3 0.0 2.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX81067.1 - 4.9e-17 62.5 0.0 9.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX81067.1 - 1.1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX81067.1 - 4.4e-07 29.6 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ORX81067.1 - 2.4e-06 26.7 0.0 3.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.12 ORX81067.1 - 6e-06 25.6 0.0 1.6e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 DREV methyltransferase NodS PF05401.11 ORX81067.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 ORX81067.1 - 0.00015 20.9 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 ORX81067.1 - 0.00041 20.0 0.1 0.00075 19.1 0.0 1.4 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ORX81067.1 - 0.00079 18.8 0.0 0.0056 16.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 ORX81067.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 ORX81067.1 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX81067.1 - 0.0052 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORX81067.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ORX81067.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 ORX81067.1 - 0.023 14.2 0.0 2.7 7.4 0.0 2.9 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.26 ORX81067.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PAC4 PF16093.5 ORX81068.1 - 1.6e-17 63.5 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Acetyltransf_1 PF00583.25 ORX81099.1 - 0.0016 18.6 0.1 0.0019 18.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX81099.1 - 0.0049 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNase_T PF00929.24 ORX81100.1 - 3e-28 99.4 0.0 3.4e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ORX81100.1 - 0.00059 19.9 0.0 0.00069 19.6 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Cyt-b5 PF00173.28 ORX81101.1 - 5.1e-20 71.4 0.1 1.1e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORX81101.1 - 1.4e-15 57.8 16.1 1.4e-15 57.8 16.1 2.3 1 1 1 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.32 ORX81102.1 - 5.4e-11 42.9 7.6 1.8 9.6 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 ORX81102.1 - 0.012 15.7 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 ORX81102.1 - 0.046 13.1 0.1 0.97 8.7 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain Leader_Erm PF08253.11 ORX81102.1 - 2.3 8.7 4.4 60 4.3 0.4 3.5 3 0 0 3 3 3 0 Erm Leader peptide Ribosomal_L39 PF00832.20 ORX81103.1 - 5.1e-23 80.4 10.8 5.8e-23 80.3 10.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein She9_MDM33 PF05546.11 ORX81104.1 - 1.2e-67 227.6 8.0 1.2e-67 227.6 8.0 1.5 2 0 0 2 2 2 1 She9 / Mdm33 family NleF_casp_inhib PF16809.5 ORX81104.1 - 0.0048 16.8 11.0 0.84 9.5 0.1 2.5 2 0 0 2 2 2 2 NleF caspase inhibitor YabA PF06156.13 ORX81104.1 - 0.017 15.7 9.2 1.1 9.9 0.1 2.7 2 0 0 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 ORX81104.1 - 0.18 12.5 5.9 0.8 10.4 0.4 3.2 3 0 0 3 3 3 0 SlyX Phage_GPO PF05929.11 ORX81104.1 - 0.99 9.0 7.8 0.19 11.3 0.5 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc24 PF08286.11 ORX81104.1 - 1.6 9.0 9.1 6.7 7.0 0.0 3.2 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 DUF445 PF04286.12 ORX81104.1 - 1.8 8.3 14.0 3.9 7.2 14.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Spc7 PF08317.11 ORX81104.1 - 2.2 7.1 17.6 0.56 9.0 3.0 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 ORX81104.1 - 4.7 7.2 16.5 3.3 7.7 1.9 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 ORX81104.1 - 6.7 7.2 18.9 0.55 10.7 1.4 3.3 3 1 0 3 3 3 0 Cell division protein ZapB DUF4407 PF14362.6 ORX81104.1 - 7 5.9 13.8 0.18 11.1 2.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Trm112p PF03966.16 ORX81105.1 - 1.4e-19 70.4 0.1 1.8e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-BED PF02892.15 ORX81105.1 - 0.088 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger ADK_lid PF05191.14 ORX81105.1 - 0.092 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid SNARE_assoc PF09335.11 ORX81106.1 - 6.5e-19 68.6 4.0 6.5e-19 68.6 4.0 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF676 PF05057.14 ORX81106.1 - 0.09 12.3 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CitMHS PF03600.16 ORX81106.1 - 4.7 6.3 10.2 26 3.9 10.0 1.8 1 1 0 1 1 1 0 Citrate transporter AhpC-TSA PF00578.21 ORX81108.1 - 4.1e-38 130.1 0.0 5.5e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX81108.1 - 1.7e-17 63.5 0.0 2.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORX81108.1 - 8.2e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 ORX81108.1 - 0.0019 18.1 0.3 0.004 17.1 0.3 1.5 1 0 0 1 1 1 1 SCO1/SenC Pribosyltran PF00156.27 ORX81109.1 - 2.7e-21 75.8 0.0 3.3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORX81109.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 ORX81109.1 - 0.051 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Abhydrolase_3 PF07859.13 ORX81110.1 - 5.7e-38 130.9 0.0 1.9e-28 99.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX81110.1 - 0.00091 18.2 0.1 0.0042 16.0 0.1 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase bZIP_1 PF00170.21 ORX81111.1 - 6.6e-09 35.7 4.4 6.6e-09 35.7 4.4 1.7 2 0 0 2 2 2 1 bZIP transcription factor PRKG1_interact PF15898.5 ORX81111.1 - 0.0024 18.8 2.1 0.0067 17.3 2.1 1.7 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 ORX81111.1 - 0.34 11.0 8.8 1.3 9.2 8.8 1.9 1 1 0 1 1 1 0 Basic region leucine zipper His_biosynth PF00977.21 ORX81112.1 - 1e-46 159.3 0.1 3.3e-46 157.6 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 ORX81112.1 - 2.3e-21 76.4 0.0 3.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ORX81112.1 - 5.3e-07 29.7 0.0 2.4e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORX81112.1 - 2e-05 24.3 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ORX81112.1 - 0.03 14.1 0.2 0.12 12.1 0.2 1.9 1 1 0 1 1 1 0 Peptidase C26 MOZART1 PF12554.8 ORX81113.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated zf-RING_2 PF13639.6 ORX81140.1 - 7.5e-11 42.2 10.5 1.2e-10 41.6 10.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORX81140.1 - 4.1e-08 33.4 11.3 1.3e-07 31.8 11.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORX81140.1 - 1.1e-07 31.5 11.9 3.6e-07 29.9 11.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX81140.1 - 2.8e-06 27.1 10.9 4.6e-06 26.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX81140.1 - 2.6e-05 23.9 3.1 2.6e-05 23.9 3.1 2.3 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ORX81140.1 - 3.1e-05 23.8 9.3 4.6e-05 23.3 9.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORX81140.1 - 8e-05 22.6 7.3 0.0002 21.3 7.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORX81140.1 - 0.00012 22.0 9.7 0.00012 22.0 9.7 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORX81140.1 - 0.0003 20.6 8.2 0.00056 19.7 8.2 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX81140.1 - 0.0011 18.8 8.2 0.0021 17.9 8.2 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 ORX81140.1 - 0.0015 18.7 4.7 0.027 14.7 4.7 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 ORX81140.1 - 0.0034 17.6 0.9 0.0034 17.6 0.9 1.7 1 1 1 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORX81140.1 - 0.025 14.8 4.4 0.066 13.4 4.4 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain Zf_RING PF16744.5 ORX81140.1 - 0.069 13.3 2.8 0.15 12.2 2.8 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 ORX81140.1 - 0.14 12.5 6.4 0.35 11.2 6.4 1.7 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 ORX81140.1 - 0.21 11.8 7.5 0.4 10.9 7.5 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 ORX81140.1 - 0.32 10.9 7.3 0.54 10.2 6.6 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 ORX81140.1 - 0.62 10.0 5.4 0.9 9.5 5.4 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-Nse PF11789.8 ORX81140.1 - 0.7 9.8 5.5 1.3 8.9 5.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 ORX81140.1 - 0.73 9.5 9.0 0.36 10.5 5.1 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 ORX81140.1 - 0.82 9.9 6.4 0.27 11.4 3.7 1.6 2 0 0 2 2 2 0 Zinc-ribbon like family zf-RING_4 PF14570.6 ORX81140.1 - 1.2 9.0 8.2 3.6 7.5 8.4 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain AhpC-TSA PF00578.21 ORX81141.1 - 3.1e-30 104.6 0.0 4.4e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORX81141.1 - 6e-14 51.6 0.0 9.6e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORX81141.1 - 1.3e-11 44.4 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF21 PF01595.20 ORX81142.1 - 8.2e-40 136.4 0.1 1.2e-39 135.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORX81142.1 - 3.5e-07 30.6 0.1 0.00068 20.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Fumarate_red_D PF02313.17 ORX81142.1 - 0.013 15.6 1.8 0.013 15.6 1.8 1.6 2 0 0 2 2 2 0 Fumarate reductase subunit D Stk19 PF10494.9 ORX81143.1 - 3.9e-31 108.6 0.7 1.1e-30 107.1 0.7 1.6 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 DisA-linker PF10635.9 ORX81143.1 - 0.023 14.5 0.2 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region HhH-GPD PF00730.25 ORX81144.1 - 1.8e-19 70.2 0.1 3.2e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORX81144.1 - 1.5e-08 34.0 0.0 3.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ORX81144.1 - 0.004 17.7 0.1 0.27 11.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 ORX81144.1 - 0.014 15.8 3.3 0.026 14.8 3.3 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF2400 PF09674.10 ORX81144.1 - 0.039 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Lactamase_B PF00753.27 ORX81145.1 - 3.5e-15 56.5 2.1 4.3e-14 53.0 2.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_2 PF07719.17 ORX81145.1 - 1.5e-07 31.0 8.2 1.3e-05 24.9 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX81145.1 - 0.00012 21.7 1.1 0.00012 21.7 1.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX81145.1 - 0.00015 21.4 0.6 0.00015 21.4 0.6 3.3 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 ORX81145.1 - 0.00062 20.4 1.0 0.0049 17.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX81145.1 - 0.0019 18.6 0.1 0.0019 18.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 ORX81145.1 - 0.019 14.5 0.0 0.074 12.6 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain NRBF2_MIT PF17169.4 ORX81145.1 - 0.031 14.5 0.8 0.09 13.0 0.1 2.0 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 DUF3856 PF12968.7 ORX81145.1 - 0.032 14.3 3.1 0.67 10.0 3.1 2.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 ORX81145.1 - 0.047 14.1 3.5 1.2 9.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX81145.1 - 0.08 13.0 5.2 0.49 10.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX81145.1 - 0.099 12.9 6.1 0.24 11.7 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX81145.1 - 0.16 12.2 9.5 0.12 12.7 0.6 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat HemY_N PF07219.13 ORX81145.1 - 0.31 11.2 2.5 14 6.0 0.2 2.4 2 0 0 2 2 2 0 HemY protein N-terminus MIT PF04212.18 ORX81145.1 - 0.37 10.9 6.2 2.8 8.1 0.6 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 ORX81145.1 - 3.8 7.8 9.3 1.7 8.9 1.9 2.4 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORX81145.1 - 5.3 7.8 7.3 2.3 9.0 0.5 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 ORX81145.1 - 9.7 7.5 10.0 1.6 9.8 0.8 3.8 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat ADP_ribosyl_GH PF03747.14 ORX81146.1 - 7.9e-40 137.4 0.0 9.1e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase U3snoRNP10 PF12397.8 ORX81146.1 - 0.026 14.9 0.5 0.24 11.8 0.1 2.5 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 STIMATE PF12400.8 ORX81147.1 - 7e-38 130.0 6.8 7e-38 130.0 6.8 1.5 2 0 0 2 2 2 1 STIMATE family FtsX PF02687.21 ORX81147.1 - 0.096 13.2 7.1 0.083 13.4 1.4 2.8 2 1 1 3 3 3 0 FtsX-like permease family zf-HIT PF04438.16 ORX81148.1 - 2.2e-08 33.8 13.4 3.5e-08 33.2 13.4 1.3 1 0 0 1 1 1 1 HIT zinc finger dsDNA_bind PF01984.20 ORX81148.1 - 0.038 14.3 2.1 0.057 13.7 2.1 1.3 1 0 0 1 1 1 0 Double-stranded DNA-binding domain zf-B_box PF00643.24 ORX81148.1 - 0.29 11.3 10.4 0.45 10.7 10.4 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 ORX81148.1 - 0.29 11.2 11.2 0.1 12.7 8.8 1.5 2 0 0 2 2 2 0 MYND finger zf-C2H2 PF00096.26 ORX81149.1 - 1.4e-15 56.8 13.2 0.0001 22.6 0.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX81149.1 - 2.8e-11 43.3 12.9 0.0008 20.0 1.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX81149.1 - 7.6e-10 38.8 4.6 2.6e-05 24.4 0.3 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX81149.1 - 9.5e-10 38.2 9.8 0.0025 17.7 0.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 ORX81149.1 - 9e-06 25.9 6.5 0.044 14.2 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX81149.1 - 5e-05 23.5 6.4 0.95 9.8 0.1 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 ORX81149.1 - 0.00089 18.8 1.8 0.71 9.5 0.1 2.3 1 1 1 2 2 2 2 MYST family zinc finger domain zf-C2H2_8 PF15909.5 ORX81149.1 - 0.0015 18.8 1.4 0.0015 18.8 1.4 1.9 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX81149.1 - 0.0017 18.1 7.8 0.12 12.1 0.4 2.6 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 ORX81149.1 - 0.0028 18.3 1.2 0.076 13.7 0.2 2.1 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 ORX81149.1 - 0.0053 16.8 1.2 0.15 12.2 0.2 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zf_ZIC PF18366.1 ORX81149.1 - 0.0096 16.0 3.5 0.93 9.6 0.1 3.0 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-AN1 PF01428.16 ORX81149.1 - 0.01 16.0 7.2 0.4 10.9 0.4 2.4 3 0 0 3 3 2 0 AN1-like Zinc finger zf_UBZ PF18439.1 ORX81149.1 - 0.013 15.1 2.3 0.35 10.5 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 ORX81149.1 - 0.037 14.2 1.8 0.11 12.8 1.6 1.7 1 1 1 2 2 2 0 TFIIH C1-like domain TFIIS_C PF01096.18 ORX81149.1 - 0.066 13.1 0.7 2.8 7.9 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2HC_2 PF13913.6 ORX81149.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.3 3 1 1 4 4 4 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX81149.1 - 0.17 11.7 0.6 0.17 11.7 0.6 4.3 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORX81149.1 - 0.36 11.3 8.0 0.44 11.0 1.0 2.7 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 ORX81149.1 - 0.39 10.8 6.3 2.7 8.1 0.2 2.9 3 0 0 3 3 3 0 XPA protein N-terminal zf-BED PF02892.15 ORX81149.1 - 0.53 10.4 5.7 5 7.2 0.2 2.9 3 0 0 3 3 3 0 BED zinc finger zf_C2H2_ZHX PF18387.1 ORX81149.1 - 5.4 6.7 8.0 7.1 6.4 0.8 2.4 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Cation_efflux PF01545.21 ORX81150.1 - 4.9e-43 147.2 3.9 6.6e-43 146.8 3.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORX81150.1 - 2.9e-05 24.1 0.0 7.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter RBD-FIP PF09457.10 ORX81150.1 - 0.041 13.8 0.2 0.34 10.8 0.1 2.4 3 0 0 3 3 3 0 FIP domain TraG_N PF07916.11 ORX81150.1 - 0.13 11.0 0.0 0.44 9.3 0.0 1.8 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Baculo_Y142 PF04913.12 ORX81150.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein Pectate_lyase_3 PF12708.7 ORX81151.1 - 0.0039 17.0 0.1 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 Pectate lyase superfamily protein Ppx-GppA PF02541.16 ORX81152.1 - 8.6e-23 81.2 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family HrpB1_HrpK PF09613.10 ORX81152.1 - 0.06 13.0 0.5 0.7 9.5 0.0 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) RGS PF00615.19 ORX81180.1 - 1.4e-15 57.6 3.1 2.5e-15 56.8 3.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain NPP PF08384.10 ORX81181.1 - 5.4 7.2 21.2 2.2 8.4 0.5 4.3 2 2 1 3 3 3 0 Pro-opiomelanocortin, N-terminal region RGS PF00615.19 ORX81182.1 - 6e-12 45.9 0.2 8.6e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Amidohydro_1 PF01979.20 ORX81183.1 - 3.3e-71 240.4 0.0 4.2e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX81183.1 - 7.3e-09 35.6 0.0 5.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family RGS PF00615.19 ORX81184.1 - 1.9e-15 57.1 2.0 3.2e-15 56.5 2.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF5504 PF17608.2 ORX81184.1 - 1.7 8.8 8.1 0.75 9.9 0.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5504) Sulfotransfer_3 PF13469.6 ORX81185.1 - 1.1e-18 68.4 0.0 2.4e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORX81185.1 - 1.6e-05 24.5 1.1 0.057 12.9 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_4 PF17784.1 ORX81185.1 - 0.0068 16.3 0.1 0.24 11.2 0.1 2.5 1 1 0 1 1 1 1 Sulfotransferase domain SUKH_6 PF14568.6 ORX81185.1 - 0.017 15.5 0.0 0.049 14.0 0.0 1.8 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 ORX81185.1 - 0.053 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) MatE PF01554.18 ORX81186.1 - 4.9e-64 214.8 25.2 6.4e-32 110.4 7.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 ORX81186.1 - 5.2e-09 36.3 24.1 3.7e-08 33.5 6.8 3.7 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 ORX81186.1 - 0.02 15.0 0.1 0.02 15.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mito_carr PF00153.27 ORX81215.1 - 2.2e-57 191.0 3.6 2.7e-20 72.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CSN8_PSD8_EIF3K PF10075.9 ORX81216.1 - 4.6e-29 101.3 1.7 6.1e-29 100.9 1.7 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF2536 PF10750.9 ORX81216.1 - 0.0033 17.3 0.5 0.52 10.2 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF2536) SAC3_GANP PF03399.16 ORX81216.1 - 0.0061 16.0 0.3 0.0083 15.5 0.3 1.3 1 0 0 1 1 1 1 SAC3/GANP family AbiJ_NTD5 PF18865.1 ORX81216.1 - 0.11 12.4 0.5 3.9 7.3 0.0 2.7 3 0 0 3 3 3 0 AbiJ N-terminal domain 5 Ribosomal_L4 PF00573.22 ORX81217.1 - 2.1e-40 138.5 1.5 3.2e-40 137.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORX81217.1 - 2.8e-29 101.0 1.3 2.8e-29 101.0 1.3 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Arm PF00514.23 ORX81220.1 - 6.5e-95 308.6 11.4 5.8e-13 48.4 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 ORX81220.1 - 2.1e-25 89.0 2.5 4.2e-25 88.0 2.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 ORX81220.1 - 1.5e-23 82.8 5.4 2.1e-08 34.5 0.0 6.4 5 2 2 7 7 7 3 HEAT-like repeat Arm_3 PF16186.5 ORX81220.1 - 1.8e-23 81.9 1.7 4e-23 80.7 1.7 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 ORX81220.1 - 7e-21 74.4 0.2 1.2e-08 35.2 0.0 6.4 2 1 3 6 6 6 5 HEAT repeats HEAT PF02985.22 ORX81220.1 - 1.3e-16 59.3 3.8 3.7e-06 26.7 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat Adaptin_N PF01602.20 ORX81220.1 - 1.3e-05 24.0 0.0 0.0015 17.2 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 ORX81220.1 - 1.9e-05 24.2 0.0 0.57 9.6 0.0 3.6 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 ORX81220.1 - 2.4e-05 24.4 0.0 1.1 9.4 0.0 4.3 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 ORX81220.1 - 0.00038 20.9 0.1 0.48 11.2 0.0 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 ORX81220.1 - 0.0006 20.0 3.2 0.055 13.7 0.1 4.1 3 3 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 ORX81220.1 - 0.0014 18.2 0.0 6.8 6.2 0.0 4.6 1 1 4 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 ORX81220.1 - 0.0055 16.1 0.0 0.24 10.7 0.0 2.4 1 1 0 2 2 2 1 Mo25-like Atx10homo_assoc PF09759.9 ORX81220.1 - 0.0062 16.5 0.1 0.31 11.1 0.0 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain FA_desaturase PF00487.24 ORX81221.1 - 2.9e-18 66.6 15.3 2.9e-18 66.6 15.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORX81221.1 - 7.6e-18 64.4 0.3 2.7e-17 62.6 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1053 PF06327.14 ORX81222.1 - 7.6e-06 26.4 7.0 11 6.6 0.1 6.1 4 2 1 6 6 6 3 Domain of Unknown Function (DUF1053) DUF4054 PF13262.6 ORX81222.1 - 0.042 13.9 44.6 4.6 7.3 0.4 10.4 5 4 8 13 13 13 0 Protein of unknown function (DUF4054) RP854 PF17460.2 ORX81222.1 - 0.068 12.9 0.2 1.4e+02 2.0 0.0 4.9 4 2 1 6 6 6 0 Uncharacterized protein RP854 DUF1053 PF06327.14 ORX81223.1 - 0.16 12.6 8.5 8.2 7.1 0.1 4.5 2 2 4 6 6 6 0 Domain of Unknown Function (DUF1053) DUF4054 PF13262.6 ORX81223.1 - 1.7 8.7 44.4 2.5 8.2 0.4 9.7 3 3 9 12 12 12 0 Protein of unknown function (DUF4054) DAO PF01266.24 ORX81224.1 - 1.7e-10 41.0 0.0 3.3e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase PAS PF00989.25 ORX81249.1 - 5.6e-13 48.9 0.0 7.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ORX81249.1 - 1.1e-12 48.0 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 ORX81249.1 - 5.5e-07 29.7 0.0 9.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 ORX81249.1 - 5.5e-07 29.8 0.0 8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX81249.1 - 5.5e-06 26.6 0.0 7.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 PAS fold AOX PF01786.17 ORX81250.1 - 3.4e-85 285.0 0.4 4.7e-85 284.6 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase Ribosomal_L3 PF00297.22 ORX81251.1 - 2e-15 56.7 1.1 3.6e-14 52.5 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L3 HlyIII PF03006.20 ORX81252.1 - 1.7e-62 211.1 20.1 4.3e-62 209.8 20.1 1.6 1 1 0 1 1 1 1 Haemolysin-III related YwiC PF14256.6 ORX81252.1 - 0.035 14.4 0.8 0.035 14.4 0.8 2.5 3 1 0 3 3 3 0 YwiC-like protein PIN_8 PF18476.1 ORX81253.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 PIN like domain Cyclin_N PF00134.23 ORX81254.1 - 8.2e-09 35.3 0.1 1.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX81254.1 - 1.5e-06 28.7 0.1 1.9e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cation_ATPase_N PF00690.26 ORX81254.1 - 0.048 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF3712 PF12505.8 ORX81255.1 - 1.5e-35 122.2 1.7 2.2e-22 79.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORX81255.1 - 6e-05 23.5 0.7 2.9 8.5 0.0 4.5 4 1 0 4 4 4 2 Late embryogenesis abundant protein Xan_ur_permease PF00860.20 ORX81256.1 - 1.7e-31 109.3 32.2 6.3e-30 104.2 32.2 2.2 1 1 0 1 1 1 1 Permease family Slx4 PF09494.10 ORX81257.1 - 9.4e-09 35.1 0.0 2.5e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Slx4 endonuclease SAP PF02037.27 ORX81257.1 - 0.21 11.4 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 SAP domain WIF PF02019.18 ORX81259.1 - 0.0037 17.0 0.1 0.0073 16.0 0.1 1.4 1 0 0 1 1 1 1 WIF domain Ribosomal_L31 PF01197.18 ORX81259.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 ABC2_membrane PF01061.24 ORX81260.1 - 1.5e-85 285.9 60.4 3.7e-47 160.5 25.1 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORX81260.1 - 1.5e-37 129.1 0.0 1.8e-17 64.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORX81260.1 - 6.9e-29 99.6 10.2 1.1e-22 79.7 0.0 3.8 3 1 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX81260.1 - 1.8e-12 47.7 0.0 7.1e-12 45.8 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 ORX81260.1 - 2e-07 31.0 0.0 0.00047 20.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 ORX81260.1 - 7.5e-07 29.3 0.1 0.0043 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORX81260.1 - 1.2e-05 24.6 13.3 1.2e-05 24.6 13.3 4.0 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_18 PF13238.6 ORX81260.1 - 0.00011 22.8 0.0 0.1 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORX81260.1 - 0.00019 21.1 0.0 0.016 14.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX81260.1 - 0.0002 21.6 0.1 0.99 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORX81260.1 - 0.00033 21.1 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ORX81260.1 - 0.00048 19.8 0.1 0.0061 16.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORX81260.1 - 0.0009 19.3 0.0 0.93 9.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 ORX81260.1 - 0.0046 16.6 0.1 0.51 9.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORX81260.1 - 0.0055 16.9 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX81260.1 - 0.012 15.4 0.3 2.1 8.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORX81260.1 - 0.016 15.6 0.0 5.3 7.5 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX81260.1 - 0.025 14.5 0.1 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 ORX81260.1 - 0.026 14.8 0.4 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORX81260.1 - 0.026 14.3 0.3 4.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 ORX81260.1 - 0.037 13.9 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ploopntkinase3 PF18751.1 ORX81260.1 - 0.053 13.4 0.1 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 ORX81260.1 - 0.057 12.7 0.0 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 ORX81260.1 - 0.067 12.9 0.2 14 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 ORX81260.1 - 0.16 12.3 0.0 27 5.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PIF1 PF05970.14 ORX81260.1 - 0.17 11.0 0.0 0.73 8.9 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase AAA_23 PF13476.6 ORX81260.1 - 0.2 12.1 0.5 0.62 10.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain ODC_AZ PF02100.17 ORX81261.1 - 4.7e-16 58.8 0.0 8.5e-16 58.0 0.0 1.4 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme Citrate_synt PF00285.21 ORX81262.1 - 3.2e-104 348.9 0.0 4.2e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FRB_dom PF08771.11 ORX81262.1 - 0.12 12.8 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain LSM PF01423.22 ORX81263.1 - 2.1e-17 62.5 0.2 2.7e-17 62.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.15 ORX81264.1 - 4.4e-72 242.6 0.0 6.7e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORX81264.1 - 2.5e-25 88.3 0.3 4.5e-25 87.5 0.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORX81264.1 - 3e-18 66.3 0.0 6.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORX81264.1 - 7e-17 61.2 3.0 1.5e-16 60.1 3.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORX81264.1 - 3.2e-09 36.6 0.0 9.5e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Pmp3 PF01679.17 ORX81265.1 - 9.1e-22 77.0 7.5 1e-21 76.8 7.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DnaJ PF00226.31 ORX81266.1 - 2.6e-24 85.1 2.5 4.4e-24 84.4 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 ORX81266.1 - 1.7e-21 77.1 36.7 1.4e-16 61.0 21.0 2.2 2 1 1 3 3 3 2 Transmembrane Fragile-X-F protein Phage_holin_3_6 PF07332.11 ORX81266.1 - 2.9 8.0 26.0 0.14 12.2 0.3 4.0 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III RAMP4 PF06624.12 ORX81266.1 - 6.3 6.9 6.0 0.82 9.8 0.4 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 His_Phos_2 PF00328.22 ORX81301.1 - 8.4e-29 101.1 0.1 1.5e-28 100.3 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_transf_34 PF05637.12 ORX81302.1 - 1.6e-36 126.3 10.1 4.8e-34 118.1 10.1 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_H_20C_C PF18088.1 ORX81302.1 - 0.0029 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain E1-E2_ATPase PF00122.20 ORX81303.1 - 4.7e-43 146.8 3.1 4.7e-43 146.8 3.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX81303.1 - 2.1e-19 70.7 0.1 9.3e-19 68.5 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX81303.1 - 1e-11 44.4 0.0 2.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX81303.1 - 0.011 15.5 0.6 0.026 14.3 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX81304.1 - 4.2e-43 147.0 3.1 4.2e-43 147.0 3.1 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX81304.1 - 1.9e-19 70.8 0.0 8.5e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX81304.1 - 9.4e-12 44.4 0.0 2.6e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX81304.1 - 0.01 15.6 0.6 0.024 14.4 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fe-S_biosyn PF01521.20 ORX81305.1 - 1.8e-18 66.7 0.0 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Gti1_Pac2 PF09729.9 ORX81307.1 - 6.6e-46 156.7 4.4 6.6e-39 133.9 0.9 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family ELO PF01151.18 ORX81308.1 - 2e-62 211.0 23.7 2.4e-62 210.7 23.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CCSMST1 PF15013.6 ORX81308.1 - 6.7 7.0 7.6 7.3 6.8 0.8 2.5 1 1 1 2 2 2 0 CCSMST1 family Myb_DNA-bind_4 PF13837.6 ORX81309.1 - 4.5e-16 59.0 1.1 4.5e-16 59.0 1.1 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX81309.1 - 3.2e-05 24.1 1.0 3.2e-05 24.1 1.0 2.0 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX81309.1 - 0.0011 19.1 2.2 0.0035 17.5 2.2 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX81309.1 - 0.012 15.9 0.3 0.012 15.9 0.3 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Haemocyan_bet_s PF14830.6 ORX81309.1 - 0.065 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich ALMT PF11744.8 ORX81309.1 - 0.13 11.0 5.4 0.17 10.7 5.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Myb_DNA-bind_3 PF12776.7 ORX81309.1 - 0.19 12.7 0.2 0.19 12.7 0.2 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Glucan_synthase PF02364.15 ORX81310.1 - 0 1228.7 0.0 0 1227.9 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORX81310.1 - 4.1e-38 130.6 1.6 1.6e-37 128.7 1.6 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RhoGEF PF00621.20 ORX81311.1 - 7.8e-45 153.3 0.8 1.4e-44 152.5 0.8 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 ORX81311.1 - 3.5e-22 78.3 24.3 8.8e-18 64.2 8.2 2.5 2 0 0 2 2 2 2 FYVE zinc finger PH PF00169.29 ORX81311.1 - 9e-07 29.4 1.2 1.9e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 ORX81311.1 - 0.0025 17.6 0.3 0.041 13.7 0.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.16 ORX81311.1 - 0.0045 17.2 18.8 0.051 13.8 5.6 2.7 2 0 0 2 2 2 2 FYVE-type zinc finger Ribosomal_S17 PF00366.20 ORX81312.1 - 1.3e-24 86.1 0.3 1.6e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4519 PF15012.6 ORX81313.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF2407_C PF13373.6 ORX81313.1 - 0.18 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF4750 PF15938.5 ORX81314.1 - 3.9e-11 42.4 1.6 5.7e-11 41.9 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) DUF4834 PF16118.5 ORX81314.1 - 0.0013 19.7 0.0 0.0016 19.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) NUDIX PF00293.28 ORX81315.1 - 1e-16 61.2 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 ORX81315.1 - 1.6e-13 51.2 0.0 4.9e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ORX81315.1 - 0.00019 21.0 2.1 0.00037 20.1 2.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Transposase_31 PF04754.12 ORX81315.1 - 0.034 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative transposase, YhgA-like ketoacyl-synt PF00109.26 ORX81340.1 - 1.9e-77 260.3 0.0 2.8e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ORX81340.1 - 4.1e-59 200.7 0.1 6.1e-59 200.1 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ORX81340.1 - 1.7e-49 168.7 0.0 2.5e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ORX81340.1 - 6.7e-36 122.9 0.1 1.3e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORX81340.1 - 5.2e-18 65.6 0.0 1.4e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORX81340.1 - 7.7e-18 65.0 0.0 3e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 ORX81340.1 - 9e-12 45.6 0.0 4e-10 40.3 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX81340.1 - 8.9e-09 35.9 0.2 1.3e-07 32.2 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX81340.1 - 4.4e-07 29.8 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX81340.1 - 1.4e-06 28.2 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 ORX81340.1 - 3.7e-05 23.2 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 ORX81340.1 - 0.0017 18.2 0.1 0.0052 16.6 0.1 1.8 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_33 PF10017.9 ORX81340.1 - 0.052 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_7 PF03492.15 ORX81341.1 - 5.5e-28 98.1 0.1 1e-27 97.2 0.1 1.4 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase E1_UFD PF09358.10 ORX81341.1 - 0.11 13.2 0.1 0.28 11.9 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin fold domain Acetyltransf_1 PF00583.25 ORX81342.1 - 6.2e-13 49.0 0.0 7.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX81342.1 - 1.5e-08 34.6 0.2 1.8e-08 34.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX81342.1 - 2.8e-06 27.6 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX81342.1 - 5.4e-06 26.3 0.2 1.4e-05 25.0 0.1 1.6 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_15 PF17013.5 ORX81342.1 - 0.0097 15.4 0.5 0.0097 15.4 0.5 1.9 2 0 0 2 2 2 1 Putative acetyl-transferase Phage_TTP_1 PF04630.12 ORX81342.1 - 0.083 12.2 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Phage tail tube protein RabGAP-TBC PF00566.18 ORX81343.1 - 5e-44 150.5 16.6 6.5e-43 146.9 16.6 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TRIC PF05197.13 ORX81344.1 - 8.4e-11 41.8 0.4 1.3e-10 41.2 0.4 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 ORX81344.1 - 0.0026 17.6 3.7 0.041 13.8 1.7 2.5 2 1 0 2 2 2 2 UPF0126 domain Metallophos PF00149.28 ORX81345.1 - 4.2e-37 128.6 0.0 6.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 ORX81345.1 - 0.096 12.4 0.8 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF4211 PF13926.6 ORX81346.1 - 4.8e-19 68.8 0.1 1.3e-18 67.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) NifT PF06988.11 ORX81346.1 - 0.094 12.5 0.1 13 5.7 0.0 2.6 2 0 0 2 2 2 0 NifT/FixU protein Neuropep_like PF15161.6 ORX81346.1 - 0.15 11.7 0.1 0.49 10.1 0.1 1.9 1 0 0 1 1 1 0 Neuropeptide-like Efg1 PF10153.9 ORX81346.1 - 2.8 8.3 14.0 6.5 7.1 3.1 3.3 2 1 1 3 3 3 0 rRNA-processing protein Efg1 DUF3792 PF12670.7 ORX81347.1 - 1.2 9.3 12.1 0.13 12.4 4.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) NIF PF03031.18 ORX81384.1 - 3.9e-13 49.5 0.1 5.3e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glycoprotein_G PF00802.19 ORX81385.1 - 2.4 7.5 9.5 2.5 7.4 9.5 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G CS PF04969.16 ORX81386.1 - 1.3e-10 42.1 0.2 2.8e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 CS domain Aa_trans PF01490.18 ORX81387.1 - 8.9e-63 212.4 39.5 1e-62 212.2 39.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX81387.1 - 5.8e-05 22.1 26.9 5.8e-05 22.1 26.9 1.8 1 1 0 1 1 1 1 Spore germination protein OppC_N PF12911.7 ORX81387.1 - 1 9.4 0.0 1 9.4 0.0 4.8 6 0 0 6 6 6 0 N-terminal TM domain of oligopeptide transport permease C Collagen PF01391.18 ORX81388.1 - 7.6e-05 22.4 21.2 0.00017 21.3 21.2 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) MSP1a PF11670.8 ORX81388.1 - 1.8 7.8 3.8 3.8 6.7 1.3 2.0 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) Uricase PF01014.18 ORX81389.1 - 1.9e-60 202.8 4.8 3.8e-36 124.2 2.9 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORX81389.1 - 0.00086 19.8 1.0 0.012 16.1 0.6 2.3 2 0 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORX81390.1 - 2.4e-63 212.2 3.5 8.2e-36 123.2 1.3 2.0 2 0 0 2 2 2 2 Uricase Phage_T4_gp19 PF06841.12 ORX81391.1 - 0.16 11.8 0.2 0.4 10.5 0.1 1.5 1 1 1 2 2 2 0 T4-like virus tail tube protein gp19 Metallothio_PEC PF02068.16 ORX81392.1 - 0.048 14.0 15.3 0.048 14.0 15.3 4.3 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81394.1 - 0.012 15.9 32.0 0.012 15.9 32.0 4.0 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81395.1 - 3.6 8.0 62.4 1.4 9.3 6.0 3.1 1 1 2 3 3 3 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81396.1 - 0.051 13.9 14.7 0.051 13.9 14.7 4.3 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81397.1 - 0.014 15.7 32.7 0.014 15.7 32.7 3.0 1 1 2 3 3 3 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81398.1 - 1.4 9.3 111.0 0.22 11.9 10.4 4.2 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81399.1 - 0.048 14.0 14.6 0.048 14.0 14.6 4.2 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX81400.1 - 5e-05 23.6 52.3 0.0064 16.8 28.2 2.1 1 1 1 2 2 2 2 Plant PEC family metallothionein Metallothio_2 PF01439.18 ORX81400.1 - 5.5 7.9 49.2 4.5 8.2 7.6 3.0 3 0 0 3 3 3 0 Metallothionein Metallothio PF00131.20 ORX81400.1 - 9.8 6.4 54.2 2.5 8.3 9.8 3.0 1 1 2 3 3 3 0 Metallothionein Rhodanese PF00581.20 ORX81401.1 - 3.6e-15 56.4 0.0 4.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4257 PF14074.6 ORX81402.1 - 0.0021 18.2 1.3 0.28 11.4 0.0 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF4257) Proteasome PF00227.26 ORX81403.1 - 1.7e-62 210.3 0.2 2.2e-62 209.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORX81403.1 - 3.7e-14 52.1 0.1 8.3e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chs7 PF12271.8 ORX81404.1 - 2.2e-100 335.7 16.9 2.5e-100 335.6 16.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4149 PF13664.6 ORX81404.1 - 8.1 6.8 16.6 0.79 10.1 5.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Chs7 PF12271.8 ORX81405.1 - 2.8e-97 325.5 23.2 3.2e-97 325.4 23.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cyclin_N PF00134.23 ORX81406.1 - 0.0012 18.6 0.2 0.0024 17.6 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX81406.1 - 0.012 16.0 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 0 Cyclin Ribosomal_S25 PF03297.15 ORX81407.1 - 1.4e-42 144.0 1.2 1.6e-42 143.8 1.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_CodY PF08222.11 ORX81407.1 - 0.0015 18.1 0.5 0.0022 17.5 0.1 1.5 2 0 0 2 2 2 1 CodY helix-turn-helix domain MarR_2 PF12802.7 ORX81407.1 - 0.01 15.7 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 MarR family FYVE PF01363.21 ORX81408.1 - 2.7e-23 81.9 22.2 2.7e-15 56.2 5.9 2.6 2 0 0 2 2 2 2 FYVE zinc finger Rbsn PF11464.8 ORX81408.1 - 7.3e-13 48.0 1.9 1.6e-12 47.0 1.9 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE_2 PF02318.16 ORX81408.1 - 0.003 17.8 14.2 0.078 13.2 2.3 2.9 2 1 0 2 2 2 2 FYVE-type zinc finger zf-C2H2_9 PF16293.5 ORX81408.1 - 0.012 15.4 0.4 0.012 15.4 0.4 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 ORX81408.1 - 0.02 14.1 0.3 0.044 13.0 0.3 1.6 1 0 0 1 1 1 0 Putative actin-like family DMAP_binding PF06464.11 ORX81408.1 - 0.036 14.9 1.0 0.28 12.0 0.1 2.7 2 0 0 2 2 2 0 DMAP1-binding Domain Rep_fac-A_C PF08646.10 ORX81408.1 - 0.05 13.3 4.2 0.17 11.7 4.2 1.9 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-Di19 PF05605.12 ORX81408.1 - 0.16 12.3 0.3 0.16 12.3 0.3 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ORX81408.1 - 1.2 9.8 5.0 1 10.0 0.1 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain IBR PF01485.21 ORX81408.1 - 1.4 9.2 24.5 0.046 14.0 4.0 3.6 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain LAG1-DNAbind PF09271.11 ORX81409.1 - 8.4e-48 162.8 0.2 1.3e-47 162.3 0.2 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 ORX81409.1 - 4e-24 85.6 0.0 2.2e-13 50.7 0.1 2.4 2 0 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 ORX81409.1 - 2.8e-07 30.5 0.2 1.8e-06 27.9 0.2 2.5 1 0 0 1 1 1 1 IPT/TIG domain US30 PF17624.2 ORX81409.1 - 0.044 12.8 0.6 0.089 11.8 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function p450 PF00067.22 ORX81411.1 - 1.6e-88 297.5 0.0 2.1e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DinI PF06183.13 ORX81411.1 - 0.019 15.3 0.1 0.04 14.3 0.1 1.5 1 0 0 1 1 1 0 DinI-like family DUF2205 PF10224.9 ORX81412.1 - 6.8e-16 58.0 2.2 7.5e-16 57.9 2.2 1.0 1 0 0 1 1 1 1 Short coiled-coil protein CENP-H PF05837.12 ORX81412.1 - 0.00032 21.1 2.5 0.00032 21.1 2.5 1.0 1 0 0 1 1 1 1 Centromere protein H (CENP-H) YabA PF06156.13 ORX81412.1 - 0.0076 16.9 3.5 0.0088 16.7 3.5 1.1 1 0 0 1 1 1 1 Initiation control protein YabA JIP_LZII PF16471.5 ORX81412.1 - 0.014 15.5 3.2 0.02 15.1 3.1 1.4 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 ORX81412.1 - 0.021 14.1 1.3 0.021 14.1 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 ORX81412.1 - 0.042 13.6 0.8 0.055 13.2 0.8 1.4 1 1 0 1 1 1 0 Septum formation initiator phiKZ_IP PF12699.7 ORX81412.1 - 0.048 12.8 0.5 0.051 12.7 0.5 1.0 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Sec34 PF04136.15 ORX81412.1 - 0.059 13.3 3.2 0.064 13.1 3.2 1.0 1 0 0 1 1 1 0 Sec34-like family AIG1 PF04548.16 ORX81412.1 - 0.072 12.4 1.1 0.076 12.3 1.1 1.1 1 0 0 1 1 1 0 AIG1 family RBD-FIP PF09457.10 ORX81412.1 - 0.083 12.8 3.2 0.59 10.1 3.2 2.0 1 1 0 1 1 1 0 FIP domain Mcm10 PF09332.11 ORX81412.1 - 0.091 12.2 2.4 0.09 12.2 2.4 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Syntaxin-6_N PF09177.11 ORX81412.1 - 0.1 13.2 1.5 0.11 13.1 1.5 1.0 1 0 0 1 1 1 0 Syntaxin 6, N-terminal tRNA-synt_2 PF00152.20 ORX81413.1 - 1.7e-80 270.5 0.1 2.3e-80 270.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORX81413.1 - 3.4e-12 46.2 0.0 9.7e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORX81413.1 - 1.7e-07 31.0 0.0 0.0049 16.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Velvet PF11754.8 ORX81414.1 - 2.1e-38 132.7 14.5 1.5e-30 107.0 1.4 3.1 2 1 1 3 3 3 2 Velvet factor Glyco_hydro_20 PF00728.22 ORX81415.1 - 2.9e-90 303.2 0.2 3.5e-90 303.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORX81415.1 - 3.9e-15 56.7 0.0 9.4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Fer4_12 PF13353.6 ORX81415.1 - 0.063 13.5 0.0 2.4 8.4 0.0 2.5 2 1 0 2 2 2 0 4Fe-4S single cluster domain Glyco_hydro_20b PF02838.15 ORX81415.1 - 0.11 13.3 0.0 0.31 11.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 GST_C_3 PF14497.6 ORX81416.1 - 2e-10 40.7 0.1 3.9e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX81416.1 - 9.5e-06 25.7 0.1 1.6e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX81416.1 - 0.01 16.1 0.0 0.032 14.6 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MucBP PF06458.12 ORX81416.1 - 0.042 14.8 0.2 0.082 13.9 0.2 1.4 1 0 0 1 1 1 0 MucBP domain GST_N_3 PF13417.6 ORX81416.1 - 0.043 14.2 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX81416.1 - 0.044 13.8 0.0 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Phage_Coat_Gp8 PF05371.12 ORX81416.1 - 0.14 11.9 0.5 1 9.2 0.4 2.3 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Isochorismatase PF00857.20 ORX81417.1 - 2.7e-30 105.8 0.0 3.5e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Homeodomain PF00046.29 ORX81451.1 - 3.8e-20 71.5 4.6 5.7e-20 70.9 4.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX81451.1 - 0.0036 17.2 0.3 0.0069 16.3 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Ribosom_S12_S23 PF00164.25 ORX81451.1 - 0.011 15.3 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S12/S23 BrkDBD PF09607.10 ORX81451.1 - 0.086 12.6 0.2 4.1 7.3 0.0 2.1 1 1 1 2 2 2 0 Brinker DNA-binding domain Ribosomal_S9 PF00380.19 ORX81452.1 - 6e-34 117.2 0.2 6.8e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Oxysterol_BP PF01237.18 ORX81453.1 - 1e-136 455.7 2.5 3.2e-136 454.0 2.5 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 ORX81453.1 - 7.2e-19 67.9 0.1 1.7e-18 66.7 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORX81453.1 - 3e-07 30.9 2.1 2.4e-06 28.0 1.1 3.0 3 1 0 3 3 3 1 PH domain GOLD_2 PF13897.6 ORX81453.1 - 0.00031 21.3 0.3 0.0028 18.1 0.0 2.5 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 ORX81453.1 - 0.00058 19.9 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD C2 PF00168.30 ORX81454.1 - 2e-10 40.9 0.0 2.3e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 ORX81455.1 - 1.6e-68 231.0 0.0 1.8e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX81455.1 - 3.8e-42 144.4 0.0 4.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX81455.1 - 0.0052 15.6 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX81455.1 - 0.029 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX81455.1 - 0.032 13.3 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 ORX81455.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like ING PF12998.7 ORX81456.1 - 3.8e-15 56.3 0.1 3.8e-15 56.3 0.1 1.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORX81456.1 - 9.4e-06 25.4 9.3 1.7e-05 24.6 9.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORX81456.1 - 0.00078 19.0 2.1 0.0014 18.1 2.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORX81456.1 - 0.093 13.0 4.6 0.22 11.8 4.5 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain GFO_IDH_MocA PF01408.22 ORX81458.1 - 3.7e-14 53.6 0.0 5.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX81458.1 - 1.4e-05 25.0 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF2477 PF10631.9 ORX81459.1 - 0.027 15.1 1.3 0.027 15.1 1.3 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2477) Chlamy_scaf PF09675.10 ORX81459.1 - 0.15 12.4 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Hamartin PF04388.12 ORX81460.1 - 3 6.4 11.2 3.4 6.2 11.2 1.1 1 0 0 1 1 1 0 Hamartin protein Ribosomal_S8 PF00410.19 ORX81462.1 - 1.8e-22 79.6 0.0 3e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 TMEM70 PF06979.12 ORX81463.1 - 1.2e-06 28.9 0.6 8.3e-06 26.2 1.0 1.9 1 1 1 2 2 2 1 Assembly, mitochondrial proton-transport ATP synth complex Ribosomal_S8 PF00410.19 ORX81464.1 - 1.8e-22 79.6 0.0 3e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 MFS_1 PF07690.16 ORX81465.1 - 6.5e-27 94.4 20.4 1.5e-26 93.1 20.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CD20 PF04103.15 ORX81465.1 - 0.012 15.7 0.8 0.037 14.1 0.4 2.0 2 0 0 2 2 2 0 CD20-like family MFS_1 PF07690.16 ORX81466.1 - 9.2e-28 97.2 20.7 2.1e-27 96.0 20.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CD20 PF04103.15 ORX81466.1 - 0.037 14.1 0.4 0.037 14.1 0.4 2.4 4 0 0 4 4 4 0 CD20-like family Myb_DNA-binding PF00249.31 ORX81466.1 - 0.094 12.9 0.7 0.25 11.5 0.7 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Vac_ImportDeg PF09783.9 ORX81527.1 - 2.6e-63 212.6 6.0 3.1e-63 212.4 6.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Arrestin_C PF02752.22 ORX81528.1 - 3.6e-12 46.9 0.1 1.1e-11 45.3 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX81528.1 - 1.6e-11 44.5 0.0 3.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX81528.1 - 0.026 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like VHL PF01847.16 ORX81528.1 - 0.046 13.6 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 VHL beta domain Chromo_shadow PF01393.19 ORX81529.1 - 6.7e-18 64.5 2.9 6.5e-17 61.4 0.5 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 ORX81529.1 - 1e-16 60.6 2.8 1e-16 60.6 2.8 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DTHCT PF08070.11 ORX81529.1 - 4.3 8.1 11.0 1.1 10.1 6.3 2.2 2 1 0 2 2 2 0 DTHCT (NUC029) region vATP-synt_AC39 PF01992.16 ORX81530.1 - 1e-118 396.8 0.4 1.1e-118 396.6 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Zw10 PF06248.13 ORX81531.1 - 5.1e-88 296.0 0.0 8.2e-88 295.3 0.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Occludin_ELL PF07303.13 ORX81531.1 - 0.0019 18.9 1.2 0.11 13.2 0.5 3.6 3 1 1 4 4 4 1 Occludin homology domain COG2 PF06148.11 ORX81531.1 - 0.0052 16.9 1.0 0.014 15.5 1.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Mating_N PF12731.7 ORX81531.1 - 0.088 12.9 0.7 0.42 10.7 0.1 2.5 3 0 0 3 3 3 0 Mating-type protein beta 1 SRP68 PF16969.5 ORX81532.1 - 1.5e-136 456.7 3.1 1.8e-136 456.4 3.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 SLAC1 PF03595.17 ORX81534.1 - 5e-65 219.9 41.7 5.7e-65 219.7 41.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SDF PF00375.18 ORX81564.1 - 1.1e-90 304.5 38.4 2.3e-56 191.5 24.0 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family Synaptobrevin PF00957.21 ORX81564.1 - 3.1 7.7 5.8 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Synaptobrevin DEAD PF00270.29 ORX81565.1 - 5.1e-49 166.4 0.0 8.1e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX81565.1 - 1.3e-28 99.5 0.0 3.2e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX81565.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORX81565.1 - 0.045 12.5 0.0 1.9 7.2 0.0 2.6 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PI3K_1B_p101 PF10486.9 ORX81567.1 - 2.2 5.9 4.2 2.9 5.6 4.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit OMP_b-brl PF13505.6 ORX81568.1 - 5.5e-06 26.6 0.6 6.7e-06 26.4 0.6 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain MspA PF09203.11 ORX81568.1 - 0.0029 17.5 7.0 0.0037 17.2 7.0 1.1 1 0 0 1 1 1 1 MspA OpcA PF07239.11 ORX81568.1 - 0.077 12.7 6.7 0.84 9.3 2.1 2.5 1 1 2 3 3 3 0 Outer membrane protein OpcA Fil_haemagg_2 PF13332.6 ORX81568.1 - 0.079 13.1 7.7 1.6 8.9 1.0 2.2 1 1 1 2 2 2 0 Hemagglutinin repeat OMP_b-brl_2 PF13568.6 ORX81568.1 - 0.16 11.9 1.3 0.64 10.0 0.5 1.9 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain OMP_b-brl PF13505.6 ORX81569.1 - 9.2e-07 29.1 0.9 1.2e-06 28.8 0.9 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain MspA PF09203.11 ORX81569.1 - 0.002 18.0 6.3 0.0026 17.7 6.3 1.1 1 0 0 1 1 1 1 MspA OMP_b-brl_2 PF13568.6 ORX81569.1 - 0.11 12.5 1.4 0.76 9.8 0.3 2.1 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain OpcA PF07239.11 ORX81569.1 - 0.27 10.9 7.9 2.1 8.0 2.9 2.5 1 1 2 3 3 3 0 Outer membrane protein OpcA Ribosomal_S25 PF03297.15 ORX81570.1 - 3.2e-42 142.8 1.3 3.5e-42 142.7 1.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_CodY PF08222.11 ORX81570.1 - 0.012 15.1 0.8 0.016 14.8 0.1 1.6 2 0 0 2 2 2 0 CodY helix-turn-helix domain MarR_2 PF12802.7 ORX81570.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 MarR family DUF4588 PF15251.6 ORX81571.1 - 3.6e-08 33.5 0.0 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) PPR_2 PF13041.6 ORX81572.1 - 6.5e-33 112.7 8.8 3.7e-12 46.2 0.2 6.2 2 2 4 6 6 6 6 PPR repeat family PPR_3 PF13812.6 ORX81572.1 - 4e-30 103.7 0.6 4.2e-09 36.3 0.0 4.4 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX81572.1 - 7.1e-24 83.2 5.0 1.6e-05 24.5 0.0 7.3 8 0 0 8 8 8 4 PPR repeat PPR PF01535.20 ORX81572.1 - 1.9e-23 81.0 7.8 1.6e-06 27.9 0.0 6.4 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 ORX81572.1 - 9.4e-09 34.9 0.0 1.5e-06 27.7 0.0 2.9 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX81572.1 - 0.034 15.0 0.0 34 5.6 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat ECSIT PF06239.11 ORX81572.1 - 0.043 12.9 0.0 8.4 5.4 0.0 3.0 1 1 1 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.7 ORX81572.1 - 0.044 13.6 0.2 14 5.6 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial ATPase expression WD40 PF00400.32 ORX81573.1 - 0.00038 21.2 0.8 0.04 14.8 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Hira PF07569.11 ORX81573.1 - 0.054 13.2 0.6 8.1 6.1 0.0 2.4 3 0 0 3 3 3 0 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 ORX81573.1 - 0.062 13.6 0.0 2.4 8.5 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MmgE_PrpD PF03972.14 ORX81574.1 - 0.076 11.5 0.1 0.086 11.4 0.1 1.1 1 0 0 1 1 1 0 MmgE/PrpD family TFCD_C PF12612.8 ORX81575.1 - 4.1e-51 173.5 0.7 3.5e-50 170.5 0.0 2.9 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 ORX81575.1 - 6.2e-07 29.7 2.3 1.6 9.2 0.0 5.9 7 0 0 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 ORX81575.1 - 0.034 14.8 0.2 28 5.4 0.0 4.9 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ORX81575.1 - 0.096 13.0 12.8 2.1 8.8 0.0 7.9 9 0 0 9 9 9 0 HEAT repeat SF1-HH PF16275.5 ORX81576.1 - 1.5e-40 138.0 3.8 4e-40 136.7 3.8 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 ORX81576.1 - 3e-09 36.5 8.9 0.00016 21.6 2.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 ORX81576.1 - 6.3e-09 35.5 0.4 1.3e-08 34.5 0.4 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.6 ORX81576.1 - 0.0016 18.1 7.1 0.13 12.0 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 ORX81576.1 - 0.0016 18.2 3.9 0.076 12.9 0.6 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 ORX81576.1 - 0.045 13.7 1.3 0.045 13.7 1.3 2.4 1 1 1 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 ORX81576.1 - 0.078 13.1 3.9 0.18 11.9 3.9 1.6 1 0 0 1 1 1 0 PHD-finger DnaJ_CXXCXGXG PF00684.19 ORX81576.1 - 0.088 13.2 4.4 0.2 12.0 4.4 1.6 1 0 0 1 1 1 0 DnaJ central domain AA_kinase PF00696.28 ORX81577.1 - 6.1e-38 130.8 0.4 1.3e-37 129.7 0.1 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 ORX81577.1 - 4.4e-10 39.1 1.1 3.2e-05 23.6 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 ORX81577.1 - 3e-08 33.3 3.2 1.4e-05 24.8 0.3 2.6 2 0 0 2 2 2 2 ACT domain Ribosomal_S25 PF03297.15 ORX81578.1 - 3e-42 142.9 1.3 3.2e-42 142.8 1.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_CodY PF08222.11 ORX81578.1 - 0.0086 15.6 0.4 0.015 14.9 0.1 1.5 2 0 0 2 2 2 1 CodY helix-turn-helix domain MarR_2 PF12802.7 ORX81578.1 - 0.015 15.1 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 MarR family CBS PF00571.28 ORX81580.1 - 6.6e-19 68.1 2.2 1.9e-07 31.4 0.0 5.0 4 1 0 4 4 4 4 CBS domain dCache_1 PF02743.18 ORX81580.1 - 0.01 15.6 0.1 0.018 14.8 0.1 1.5 1 1 0 1 1 1 0 Cache domain DUF4838 PF16126.5 ORX81580.1 - 0.037 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) ATP_bind_1 PF03029.17 ORX81580.1 - 0.05 13.4 0.3 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3246 PF11596.8 ORX81580.1 - 0.08 12.4 2.0 0.51 9.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Glyco_hydro_16 PF00722.21 ORX81581.1 - 6.5e-35 120.2 3.8 1e-34 119.6 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_61 PF03443.14 ORX81582.1 - 0.0013 18.7 0.1 0.097 12.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX81582.1 - 0.002 18.8 1.2 0.01 16.5 1.2 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GPI-anchored PF10342.9 ORX81582.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_18 PF00704.28 ORX81583.1 - 7.9e-67 226.2 0.6 9.4e-67 225.9 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ASH PF15780.5 ORX81620.1 - 1.4e-15 57.2 2.7 0.36 11.0 0.1 12.0 12 0 0 12 12 12 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 ORX81620.1 - 4.7e-05 23.3 0.0 21 5.2 0.0 7.8 7 2 0 7 7 7 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 ORX81620.1 - 0.0024 17.7 2.9 0.076 12.9 0.2 4.7 4 0 0 4 4 4 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 ORX81620.1 - 0.027 14.7 11.7 2.9 8.2 0.1 7.0 7 1 1 8 8 8 0 Transmembrane protein 131-like Transglut_C PF00927.22 ORX81620.1 - 0.61 10.3 5.4 9.1 6.5 0.0 5.1 7 0 0 7 7 7 0 Transglutaminase family, C-terminal ig like domain Prefoldin_2 PF01920.20 ORX81621.1 - 1.4e-16 60.3 5.6 1.8e-16 60.0 5.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PDE4_UCR PF18100.1 ORX81621.1 - 0.036 14.7 0.7 0.042 14.5 0.7 1.2 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) XhlA PF10779.9 ORX81621.1 - 0.049 13.8 0.9 0.049 13.8 0.9 2.2 2 1 0 2 2 2 0 Haemolysin XhlA SlyX PF04102.12 ORX81621.1 - 0.05 14.2 3.7 2.3 8.9 0.0 2.3 2 0 0 2 2 2 0 SlyX DUF5320 PF17253.2 ORX81621.1 - 0.55 11.3 2.2 12 7.0 2.2 2.6 1 1 0 1 1 1 0 Family of unknown function (DUF5320) DNA_topoisoIV PF00521.20 ORX81622.1 - 4.2e-125 418.0 0.0 9.2e-125 416.9 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORX81622.1 - 1.1e-48 164.7 6.1 4.2e-48 162.8 6.1 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORX81622.1 - 3.7e-26 91.6 2.7 1.2e-25 90.0 2.7 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 ORX81622.1 - 1.3e-13 51.4 0.1 4.4e-13 49.7 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORX81622.1 - 1.8e-07 31.3 0.1 1e-06 28.9 0.0 2.4 2 0 0 2 2 2 1 Toprim domain zf-C2H2 PF00096.26 ORX81623.1 - 7.7e-10 38.7 15.2 6.6e-05 23.1 5.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX81623.1 - 3.2e-08 33.6 1.2 3.2e-08 33.6 1.2 3.5 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX81623.1 - 3.7e-05 24.2 14.6 0.016 16.0 0.7 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX81623.1 - 0.00014 21.7 10.6 0.00062 19.7 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX81623.1 - 0.00029 20.5 4.7 0.031 14.0 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 ORX81623.1 - 0.02 14.8 4.6 0.072 13.0 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF768 PF05589.11 ORX81623.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF768) zf-C2H2_2 PF12756.7 ORX81623.1 - 1.8 9.0 12.2 1.8 8.9 2.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DPBB_1 PF03330.18 ORX81624.1 - 3.5e-10 40.0 0.1 5.6e-10 39.4 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX81624.1 - 9.3e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 ORX81624.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin DUF3039 PF11238.8 ORX81624.1 - 0.2 11.4 2.2 7.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) GalP_UDP_transf PF01087.22 ORX81625.1 - 6.1e-69 232.1 0.3 9.6e-69 231.5 0.3 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 ORX81625.1 - 5.5e-61 205.2 0.0 1.5e-60 203.7 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 ORX81625.1 - 3.4e-06 26.1 0.2 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) HIT PF01230.23 ORX81625.1 - 0.0033 18.1 1.8 0.57 11.0 0.9 2.6 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 ORX81625.1 - 0.012 16.1 0.2 0.039 14.4 0.0 2.0 2 1 1 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding DUF4931 PF16285.5 ORX81625.1 - 0.046 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) Exo_endo_phos PF03372.23 ORX81626.1 - 3.1e-09 36.7 0.0 1.3e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Chromo_shadow PF01393.19 ORX81628.1 - 2.4e-18 66.0 0.3 4.2e-18 65.2 0.3 1.4 1 0 0 1 1 1 1 Chromo shadow domain Ytp1 PF10355.9 ORX81629.1 - 6.5e-19 68.2 17.7 9.6e-18 64.4 14.0 3.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORX81629.1 - 7.4e-12 45.0 8.2 9e-12 44.7 0.4 3.2 2 1 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 ORX81629.1 - 2.5e-06 27.7 3.9 2.5e-06 27.7 3.9 2.9 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2306 PF10067.9 ORX81629.1 - 0.00048 20.4 2.2 0.00048 20.4 2.2 3.1 3 1 0 3 3 3 1 Predicted membrane protein (DUF2306) Ferric_reduct PF01794.19 ORX81629.1 - 0.43 10.7 11.7 1.3 9.1 5.1 3.4 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF4079 PF13301.6 ORX81629.1 - 9 6.5 16.1 0.17 12.1 3.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) Ytp1 PF10355.9 ORX81630.1 - 3.6e-50 170.7 26.1 1.1e-49 169.2 21.3 2.9 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORX81630.1 - 1.5e-20 73.0 4.6 1.5e-20 73.0 4.6 3.3 2 2 1 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 ORX81630.1 - 2.4e-08 34.2 11.8 2.4e-08 34.2 11.8 3.8 2 1 0 3 3 3 1 Eukaryotic cytochrome b561 DUF3397 PF11877.8 ORX81630.1 - 0.0061 16.7 0.8 0.0061 16.7 0.8 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF3397) Atthog PF18800.1 ORX81630.1 - 4.2 7.3 11.9 12 5.8 2.8 3.8 2 2 3 5 5 5 0 Attenuator of Hedgehog Aconitase PF00330.20 ORX81631.1 - 3.8e-108 362.4 0.0 4.7e-107 358.8 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX81631.1 - 2e-25 89.6 0.0 3.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ORX81631.1 - 0.033 12.9 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) U-box PF04564.15 ORX81632.1 - 0.00069 19.7 0.2 0.004 17.3 0.0 2.3 2 0 0 2 2 2 1 U-box domain Myb_DNA-binding PF00249.31 ORX81632.1 - 0.0097 16.1 0.3 0.22 11.8 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 ORX81632.1 - 0.43 11.0 0.1 0.43 11.0 0.1 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RHH_7 PF16777.5 ORX81632.1 - 2.6 8.5 7.0 2.2 8.7 0.2 3.3 3 0 0 3 3 3 0 Transcriptional regulator, RHH-like, CopG Ribosomal_S17e PF00833.18 ORX81633.1 - 1.2e-64 215.7 0.2 1.4e-64 215.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Antimicrobial22 PF16047.5 ORX81634.1 - 0.073 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Frog antimicrobial peptide Ribosomal_L22 PF00237.19 ORX81666.1 - 2.1e-43 146.7 0.1 2.9e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Aa_trans PF01490.18 ORX81667.1 - 1.2e-61 208.7 33.6 1.5e-61 208.3 33.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein V-ATPase_H_N PF03224.14 ORX81668.1 - 1.3e-82 277.6 5.8 1.9e-82 277.1 5.8 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORX81668.1 - 2.5e-47 159.8 4.1 8.2e-45 151.7 0.0 3.6 4 1 0 4 4 4 2 V-ATPase subunit H HEAT PF02985.22 ORX81668.1 - 9.8e-05 22.3 0.4 0.017 15.4 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 ORX81668.1 - 0.00037 20.4 0.0 19 5.5 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORX81668.1 - 0.0076 16.6 0.0 0.042 14.2 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats Arm_2 PF04826.13 ORX81668.1 - 0.0095 15.4 3.8 0.0096 15.4 0.0 2.5 3 1 0 3 3 3 1 Armadillo-like Pox_VLTF3 PF04947.14 ORX81668.1 - 0.065 13.0 0.3 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Ribosomal_L38e PF01781.18 ORX81669.1 - 1.3e-35 121.3 1.7 1.4e-35 121.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORX81669.1 - 0.066 13.4 0.0 0.076 13.2 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORX81669.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 TFIIS_M PF07500.14 ORX81670.1 - 3.1e-33 114.6 3.7 3.1e-33 114.6 3.7 1.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 ORX81670.1 - 1.1e-18 66.7 8.6 1.8e-18 66.1 8.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 ORX81670.1 - 2e-09 37.3 1.7 2.6e-09 37.0 0.2 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Usp PF00582.26 ORX81671.1 - 1.3e-21 77.6 0.0 2.3e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family Acyl-CoA_dh_1 PF00441.24 ORX81672.1 - 1.9e-41 141.8 0.6 2.7e-41 141.3 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX81672.1 - 1.8e-22 79.4 0.0 3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORX81672.1 - 8e-22 77.2 0.0 1.9e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORX81672.1 - 2.2e-21 76.6 0.0 5.5e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX81672.1 - 1.4e-07 31.8 0.1 2.3e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 ORX81673.1 - 1e-46 159.5 27.8 1.3e-46 159.1 23.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX81673.1 - 1e-12 47.7 26.2 1e-10 41.1 8.4 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.13 ORX81673.1 - 3e-07 29.2 5.7 3e-07 29.2 5.7 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORX81673.1 - 0.00094 17.6 7.8 0.00094 17.6 7.8 3.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_5 PF05631.14 ORX81673.1 - 0.044 12.7 4.4 0.044 12.7 2.0 2.1 2 1 0 2 2 2 0 Sugar-tranasporters, 12 TM Fungal_trans PF04082.18 ORX81705.1 - 1.7e-36 125.6 0.9 3.1e-36 124.8 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX81705.1 - 4.8e-10 39.4 12.2 8.7e-10 38.6 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2070 PF09843.9 ORX81706.1 - 0.16 10.2 1.3 0.18 10.1 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PBD PF00786.28 ORX81707.1 - 5.4e-08 33.1 0.0 1.4e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORX81707.1 - 5.3e-07 30.1 0.1 9.2e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 PH domain ScsC_N PF18312.1 ORX81707.1 - 0.19 11.6 0.3 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain SLC35F PF06027.12 ORX81708.1 - 2.3e-106 355.7 27.0 2.7e-106 355.5 27.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 ORX81708.1 - 1.1e-11 44.2 6.2 1.1e-11 44.2 6.2 2.0 1 1 2 3 3 3 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 ORX81708.1 - 1.8e-06 28.2 32.8 0.0012 19.0 13.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORX81708.1 - 0.00014 21.2 19.7 0.00061 19.1 19.7 1.9 1 1 0 1 1 1 1 UAA transporter family SH3_12 PF18129.1 ORX81708.1 - 0.12 12.5 0.5 0.29 11.3 0.5 1.6 1 0 0 1 1 1 0 Xrn1 SH3-like domain Aldedh PF00171.22 ORX81709.1 - 8.4e-93 311.4 0.0 1e-92 311.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NiFe_hyd_3_EhaA PF17367.2 ORX81709.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A Ribosomal_S6 PF01250.17 ORX81710.1 - 2.4e-26 91.8 0.0 2.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 UBA PF00627.31 ORX81711.1 - 1.5e-09 37.5 0.1 1.5e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 ORX81711.1 - 3.2e-08 33.2 1.0 7.3e-07 28.9 1.0 2.2 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX81711.1 - 0.00029 20.6 1.0 0.011 15.6 1.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RPN13_C PF16550.5 ORX81711.1 - 0.0026 17.9 1.9 0.0026 17.9 1.9 2.0 2 1 0 2 2 2 1 UCH-binding domain Ubiquitin_4 PF18036.1 ORX81711.1 - 0.048 13.7 0.5 0.28 11.3 0.3 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain STI1 PF17830.1 ORX81711.1 - 0.89 9.5 17.1 1.1 9.2 1.8 3.5 3 1 0 3 3 3 0 STI1 domain GerD PF17898.1 ORX81711.1 - 6 6.8 9.4 0.27 11.2 2.5 2.1 2 1 0 2 2 2 0 Spore germination GerD central core domain GST_C_6 PF17171.4 ORX81712.1 - 4.2e-19 68.1 0.0 9.1e-19 67.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORX81712.1 - 1.7e-14 54.2 0.6 1.5e-13 51.1 0.6 2.2 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ORX81712.1 - 1.2e-11 45.2 0.1 3.6e-11 43.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORX81712.1 - 3.8e-05 23.6 0.1 0.00031 20.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX81712.1 - 0.0045 17.1 0.2 0.014 15.6 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain UPF0203 PF05254.12 ORX81713.1 - 2.3e-27 95.0 2.0 2.5e-27 94.9 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 ORX81713.1 - 0.00019 21.6 3.2 0.065 13.4 0.3 2.1 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 ORX81713.1 - 0.0035 17.7 1.1 0.0092 16.3 1.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF19 PF01579.18 ORX81713.1 - 0.011 15.6 2.8 0.012 15.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF19) COX6B PF02297.17 ORX81713.1 - 0.014 15.6 1.8 0.016 15.4 1.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 ORX81713.1 - 0.093 12.8 0.9 5.2 7.2 0.1 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Mvb12 PF09452.10 ORX81713.1 - 0.13 12.7 0.5 0.2 12.1 0.4 1.5 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 DUF5339 PF17274.2 ORX81713.1 - 0.2 12.5 4.8 0.57 11.1 1.3 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Cmc1 PF08583.10 ORX81713.1 - 0.28 11.2 4.4 5.3 7.1 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Dynamitin PF04912.14 ORX81714.1 - 9.2e-34 117.4 13.7 1.1e-33 117.1 13.7 1.1 1 0 0 1 1 1 1 Dynamitin Arfaptin PF06456.13 ORX81714.1 - 0.022 14.3 0.9 0.022 14.3 0.9 2.5 1 1 1 2 2 2 0 Arfaptin-like domain YcbB PF08664.10 ORX81714.1 - 0.059 13.4 2.0 0.17 11.9 0.4 2.2 2 0 0 2 2 2 0 YcbB domain Baculo_PEP_C PF04513.12 ORX81714.1 - 0.071 13.2 10.9 0.56 10.3 4.2 2.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 ORX81714.1 - 0.17 12.3 10.2 6.2 7.2 4.7 3.4 1 1 1 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.9 ORX81714.1 - 0.23 11.8 11.4 0.84 10.0 0.9 3.7 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 ORX81714.1 - 0.27 9.1 2.6 0.35 8.7 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 ORX81714.1 - 0.55 10.4 12.2 0.36 11.0 2.8 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec34 PF04136.15 ORX81714.1 - 0.63 9.9 6.4 0.52 10.2 2.2 2.3 2 0 0 2 2 2 0 Sec34-like family Occludin_ELL PF07303.13 ORX81714.1 - 0.66 10.7 6.4 11 6.8 0.3 2.7 3 0 0 3 3 3 0 Occludin homology domain DUF2120 PF09893.9 ORX81714.1 - 1.1 9.3 5.3 0.8 9.8 1.1 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Laminin_II PF06009.12 ORX81714.1 - 1.3 9.1 11.3 6.4 6.8 1.7 3.2 2 1 1 3 3 3 0 Laminin Domain II MutS_III PF05192.18 ORX81714.1 - 2.7 8.2 9.3 4.5 7.4 9.3 1.6 1 1 0 1 1 1 0 MutS domain III Exonuc_VII_L PF02601.15 ORX81714.1 - 3 7.3 9.4 41 3.6 9.4 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 ORX81714.1 - 4.3 7.2 6.5 5.2 6.9 0.3 3.5 3 1 1 4 4 3 0 Septum formation initiator CorA PF01544.18 ORX81714.1 - 5.9 6.1 9.2 11 5.3 1.9 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein EMP24_GP25L PF01105.24 ORX81714.1 - 9.9 6.1 10.2 1.4e+02 2.4 10.2 2.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Dynamitin PF04912.14 ORX81715.1 - 1.9e-15 57.1 8.0 2.4e-15 56.8 8.0 1.0 1 0 0 1 1 1 1 Dynamitin AAA_31 PF13614.6 ORX81715.1 - 0.11 12.4 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain Cytochrom_C1 PF02167.15 ORX81715.1 - 0.14 11.8 0.6 0.15 11.7 0.6 1.1 1 0 0 1 1 1 0 Cytochrome C1 family RibD_C PF01872.17 ORX81716.1 - 2.5e-31 109.1 0.0 3.1e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain UQ_con PF00179.26 ORX81718.1 - 8.3e-50 168.1 0.0 9.5e-50 167.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORX81718.1 - 0.02 14.7 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 UEV domain Adeno_E3_14_5 PF04834.12 ORX81718.1 - 0.021 15.4 0.2 0.036 14.6 0.2 1.3 1 0 0 1 1 1 0 Early E3 14.5 kDa protein RWD PF05773.22 ORX81718.1 - 0.032 14.5 0.0 0.049 13.9 0.0 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 ORX81718.1 - 0.035 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_2 PF03142.15 ORX81719.1 - 1e-281 935.2 0.3 1.4e-281 934.7 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX81719.1 - 1.8e-10 41.1 0.1 4.6e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX81719.1 - 6.6e-10 39.2 9.3 6.6e-10 39.2 9.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX81719.1 - 0.02 14.7 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Pico_P1A PF02226.16 ORX81719.1 - 0.064 13.3 0.2 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) FDC-SP PF15215.6 ORX81719.1 - 0.092 13.3 2.1 0.27 11.8 2.1 1.8 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide MFS_1 PF07690.16 ORX81720.1 - 6.4e-18 64.8 25.9 8.6e-18 64.4 25.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX81720.1 - 2.6e-14 53.2 8.2 2.6e-14 53.2 8.2 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX81720.1 - 0.00026 20.0 2.6 0.03 13.2 6.3 2.1 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORX81720.1 - 0.039 12.9 10.5 0.061 12.3 9.1 2.0 2 1 0 2 2 2 0 PUCC protein CPP1-like PF11833.8 ORX81720.1 - 7.1 6.2 5.5 1.7 8.3 1.7 2.0 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DJ-1_PfpI PF01965.24 ORX81721.1 - 5.8e-08 32.7 0.0 2.1e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX81721.1 - 0.0036 17.0 0.1 0.0088 15.7 0.0 1.6 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX81721.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Latrotoxin C-terminal domain HSF_DNA-bind PF00447.17 ORX81760.1 - 3.5e-32 110.9 2.6 3.5e-32 110.9 2.6 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding ATG16 PF08614.11 ORX81760.1 - 0.00052 20.3 4.1 0.00089 19.5 4.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HD_assoc PF13286.6 ORX81760.1 - 0.0034 17.9 0.6 0.0081 16.7 0.6 1.6 1 0 0 1 1 1 1 Phosphohydrolase-associated domain DHR10 PF18595.1 ORX81760.1 - 0.012 15.7 8.4 0.017 15.2 8.4 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF2309 PF10070.9 ORX81760.1 - 0.018 13.4 0.4 0.025 12.9 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Vps53_N PF04100.12 ORX81760.1 - 0.019 13.9 3.2 0.029 13.3 3.2 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF3450 PF11932.8 ORX81760.1 - 0.026 13.8 5.3 0.039 13.2 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MatP_C PF17414.2 ORX81760.1 - 0.042 14.0 1.3 0.11 12.7 1.3 1.6 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain DUF1664 PF07889.12 ORX81760.1 - 0.055 13.5 0.7 0.096 12.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 ORX81760.1 - 0.097 12.8 3.3 0.15 12.1 3.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IFT57 PF10498.9 ORX81760.1 - 0.35 9.8 5.6 0.51 9.2 5.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Pheromone PF08015.11 ORX81760.1 - 0.42 11.7 2.1 4.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone SseC PF04888.12 ORX81760.1 - 1.1 8.8 4.1 1.5 8.3 4.1 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Fibrillarin PF01269.17 ORX81761.1 - 4.1e-107 356.5 0.0 5e-107 356.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORX81761.1 - 2.8e-06 27.2 0.0 4.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORX81761.1 - 0.0075 16.0 0.1 0.015 15.1 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORX81761.1 - 0.015 15.0 0.0 0.52 9.9 0.0 2.2 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORX81761.1 - 0.096 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pribosyltran PF00156.27 ORX81762.1 - 8.1e-15 54.7 0.1 1e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORX81762.1 - 0.0041 16.6 0.0 0.0072 15.8 0.0 1.6 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase ABC_membrane PF00664.23 ORX81763.1 - 6.2e-97 324.5 36.3 3.2e-50 171.3 15.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX81763.1 - 5.4e-67 224.5 0.0 3.5e-32 111.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX81763.1 - 1.1e-15 57.7 4.1 1.5e-06 27.8 0.1 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORX81763.1 - 3.6e-09 35.9 0.6 0.00028 19.8 0.0 3.5 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 ORX81763.1 - 5.5e-08 32.9 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 ORX81763.1 - 7.3e-08 33.0 0.8 0.021 15.2 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX81763.1 - 1.1e-06 28.3 1.4 0.023 14.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX81763.1 - 4.5e-06 27.0 3.0 0.26 11.6 0.1 4.3 3 2 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORX81763.1 - 5.2e-06 26.5 0.0 0.065 13.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 ORX81763.1 - 6.9e-06 26.1 0.1 0.84 9.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORX81763.1 - 8.6e-05 22.3 0.4 1.5 8.5 0.3 3.9 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 ORX81763.1 - 0.00016 21.9 0.0 0.03 14.4 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 ORX81763.1 - 0.00026 20.4 0.0 0.35 10.1 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.29 ORX81763.1 - 0.00026 21.4 0.1 11 6.4 0.2 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORX81763.1 - 0.00054 20.5 0.6 1.2 9.6 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 ORX81763.1 - 0.0014 18.6 0.0 1.5 8.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 ORX81763.1 - 0.006 15.8 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 ORX81763.1 - 0.0072 16.4 0.0 3.1 7.9 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ORX81763.1 - 0.0098 16.1 0.0 6.7 6.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORX81763.1 - 0.02 15.4 0.0 1.2 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORX81763.1 - 0.023 14.4 0.0 3.5 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 ORX81763.1 - 0.026 14.7 2.6 7.6 6.8 0.2 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 ORX81763.1 - 0.028 14.3 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 ORX81763.1 - 0.032 13.8 0.1 6.5 6.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORX81763.1 - 0.055 13.0 0.1 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 ORX81763.1 - 0.08 12.7 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3987 PF13148.6 ORX81763.1 - 0.097 11.7 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 ORX81763.1 - 0.15 11.2 0.0 15 4.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain K_oxygenase PF13434.6 ORX81764.1 - 2.1e-112 375.6 0.0 2.5e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORX81764.1 - 3.3e-10 40.2 0.0 2.9e-07 30.6 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORX81764.1 - 1.5e-08 34.3 0.0 1e-06 28.2 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX81764.1 - 9.9e-05 21.7 1.1 0.19 11.0 0.0 4.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX81764.1 - 0.014 15.0 0.0 8.2 5.9 0.0 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.17 ORX81764.1 - 0.079 12.2 0.0 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 ORX81764.1 - 0.12 11.4 0.0 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Acetyltransf_8 PF13523.6 ORX81765.1 - 7.4e-54 181.4 0.2 9.2e-54 181.1 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORX81765.1 - 0.0001 23.0 0.0 0.00027 21.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 ORX81766.1 - 1.3e-29 103.4 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX81766.1 - 2.6e-13 50.3 1.1 3.2e-10 40.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX81766.1 - 1.3e-05 24.6 0.1 0.00016 21.1 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX81766.1 - 1.3e-05 24.4 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 ORX81766.1 - 0.0018 17.5 0.0 0.0048 16.1 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORX81766.1 - 0.0024 17.1 0.3 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ORX81766.1 - 0.0039 17.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX81766.1 - 0.01 15.9 0.5 22 5.0 0.0 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding DUF1188 PF06690.11 ORX81766.1 - 0.1 12.1 0.5 0.83 9.1 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 ORX81766.1 - 0.11 11.3 0.0 9.1 5.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 ORX81766.1 - 0.22 11.1 0.2 3.2 7.3 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase Amidohydro_1 PF01979.20 ORX81767.1 - 1.4e-71 241.6 0.0 1.6e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX81767.1 - 1.5e-09 37.9 0.0 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family FAD_binding_4 PF01565.23 ORX81767.1 - 0.054 13.2 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Amidohydro_1 PF01979.20 ORX81768.1 - 1e-71 242.0 0.0 1.2e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX81768.1 - 7.3e-10 38.9 0.0 3e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family FAD_binding_4 PF01565.23 ORX81768.1 - 0.053 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 ORX81769.1 - 4.4e-17 62.1 26.5 5.9e-17 61.6 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX81769.1 - 6.1e-14 52.0 9.4 6.1e-14 52.0 9.4 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX81769.1 - 9.8e-05 21.4 0.6 0.022 13.6 5.4 2.0 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORX81769.1 - 0.028 13.4 10.0 0.076 12.0 8.9 2.2 2 1 0 2 2 2 0 PUCC protein RrnaAD PF00398.20 ORX81800.1 - 1e-20 74.0 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase XPB_DRD PF18458.1 ORX81800.1 - 0.053 13.4 0.2 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain AAA_31 PF13614.6 ORX81800.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain PELOTA_1 PF15608.6 ORX81800.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 PELOTA RNA binding domain Molybdopterin PF00384.22 ORX81801.1 - 2.2e-74 251.0 0.0 1.4e-73 248.3 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ORX81801.1 - 1e-18 67.2 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ORX81801.1 - 7.1e-17 60.7 0.1 7.1e-17 60.7 0.1 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 ORX81801.1 - 1.8e-15 57.3 0.0 4.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 ORX81801.1 - 1.8e-08 34.2 0.3 1.8e-08 34.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ORX81801.1 - 0.00073 19.3 0.0 0.055 13.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 ORX81801.1 - 0.093 12.6 1.1 4.7 7.2 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain DUF89 PF01937.19 ORX81802.1 - 1.7e-112 375.9 1.6 2e-112 375.7 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Metallophos PF00149.28 ORX81803.1 - 7e-36 124.6 0.1 1e-35 124.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX81803.1 - 4e-16 59.2 0.1 9.5e-16 58.0 0.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PMT PF02366.18 ORX81804.1 - 3.5e-79 265.9 15.9 3.5e-79 265.9 15.9 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX81804.1 - 2.5e-65 219.8 12.8 2.5e-65 219.8 12.8 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX81804.1 - 5.3e-24 85.1 2.2 5.3e-24 85.1 2.2 1.6 2 0 0 2 2 2 1 MIR domain EF_assoc_2 PF08356.12 ORX81805.1 - 8.5e-37 125.0 0.0 2.7e-36 123.5 0.0 1.9 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 ORX81805.1 - 9.5e-31 106.6 0.0 1.3e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 ORX81805.1 - 1e-25 89.1 0.6 2.1e-25 88.1 0.6 1.5 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 ORX81805.1 - 3.9e-18 65.8 0.0 2.1e-11 44.1 0.0 3.0 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 ORX81805.1 - 5.3e-09 35.3 2.7 0.0017 18.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.23 ORX81805.1 - 6.1e-08 32.7 0.0 0.00047 20.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 ORX81805.1 - 9.9e-08 32.3 3.3 0.0024 18.3 0.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORX81805.1 - 4.8e-07 28.9 7.6 0.0013 18.1 0.5 2.5 2 0 0 2 2 2 2 EF hand Arf PF00025.21 ORX81805.1 - 5e-07 29.3 0.1 0.00016 21.2 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.6 ORX81805.1 - 5.8e-07 29.9 0.1 0.07 13.4 0.0 3.3 2 2 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ORX81805.1 - 1.7e-06 28.5 0.0 0.021 15.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 ORX81805.1 - 6e-06 26.7 0.0 0.042 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 ORX81805.1 - 6.5e-06 26.2 0.0 0.15 12.0 0.2 2.9 2 1 0 2 2 2 2 NACHT domain Dynamin_N PF00350.23 ORX81805.1 - 7.3e-06 26.1 0.0 0.074 13.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family SRPRB PF09439.10 ORX81805.1 - 9.2e-06 25.2 0.1 0.0038 16.7 0.1 2.7 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORX81805.1 - 2.7e-05 24.1 1.2 0.05 13.5 0.0 3.8 4 0 0 4 4 4 1 RsgA GTPase AAA_7 PF12775.7 ORX81805.1 - 3.6e-05 23.3 0.1 0.028 14.0 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 ORX81805.1 - 4.7e-05 22.8 0.1 0.014 14.7 0.0 3.1 3 1 0 3 3 3 1 Septin AAA_29 PF13555.6 ORX81805.1 - 5.2e-05 22.9 0.2 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 ORX81805.1 - 7.4e-05 23.2 0.1 0.075 13.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX81805.1 - 0.0004 20.4 0.1 0.0071 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORX81805.1 - 0.00045 20.4 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain EF-hand_10 PF14788.6 ORX81805.1 - 0.00052 19.8 4.6 0.02 14.7 0.5 2.7 2 0 0 2 2 2 1 EF hand ATP_bind_1 PF03029.17 ORX81805.1 - 0.00063 19.6 3.1 4.3 7.1 0.2 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ORX81805.1 - 0.00071 20.1 0.0 0.12 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORX81805.1 - 0.00087 18.6 0.0 0.67 9.1 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ORX81805.1 - 0.00093 19.0 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 ORX81805.1 - 0.0027 16.9 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 ORX81805.1 - 0.0028 17.4 0.0 0.87 9.3 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 ORX81805.1 - 0.003 17.9 0.1 0.81 10.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase A-2_8-polyST PF07388.11 ORX81805.1 - 0.0039 15.9 0.2 0.006 15.2 0.2 1.2 1 0 0 1 1 1 1 Alpha-2,8-polysialyltransferase (POLYST) ATPase_2 PF01637.18 ORX81805.1 - 0.0041 17.1 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 ORX81805.1 - 0.0046 17.2 0.2 4.5 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 ORX81805.1 - 0.0047 16.9 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ORX81805.1 - 0.0087 15.7 0.0 0.26 10.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORX81805.1 - 0.016 14.9 0.1 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 ORX81805.1 - 0.016 14.3 0.1 0.088 11.9 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain Pox_A32 PF04665.12 ORX81805.1 - 0.017 14.6 0.0 3.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Ploopntkinase3 PF18751.1 ORX81805.1 - 0.018 14.9 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 EF-hand_5 PF13202.6 ORX81805.1 - 0.02 14.4 0.7 0.02 14.4 0.7 2.5 2 0 0 2 2 2 0 EF hand AAA_14 PF13173.6 ORX81805.1 - 0.023 14.7 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORX81805.1 - 0.029 13.5 0.2 5.4 6.1 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.6 ORX81805.1 - 0.03 14.7 0.1 1.5 9.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 ORX81805.1 - 0.04 13.8 2.9 0.83 9.5 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair cobW PF02492.19 ORX81805.1 - 0.044 13.4 2.1 10 5.7 0.1 3.4 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ORX81805.1 - 0.052 13.5 0.2 9.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 ORX81805.1 - 0.071 12.4 0.0 5 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 ORX81805.1 - 0.08 12.7 0.2 15 5.3 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 ORX81805.1 - 0.14 11.5 0.2 0.66 9.3 0.1 2.1 2 0 0 2 2 2 0 AIG1 family AAA_21 PF13304.6 ORX81805.1 - 0.18 11.5 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 ORX81805.1 - 0.19 11.4 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.22 ORX81805.1 - 0.22 11.1 0.5 11 5.6 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain SPARC_Ca_bdg PF10591.9 ORX81805.1 - 0.49 10.7 4.8 3.3 8.0 0.4 3.2 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region IF4E PF01652.18 ORX81806.1 - 9.8e-57 191.2 0.2 1.2e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E VHS PF00790.19 ORX81807.1 - 1e-39 135.6 0.9 1.8e-39 134.8 0.9 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 ORX81807.1 - 9.1e-16 57.2 0.1 1.9e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX81807.1 - 2.1e-13 49.7 0.2 4.5e-13 48.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORX81807.1 - 1.6e-11 43.9 1.9 1.6e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 ORX81807.1 - 1.4e-09 38.2 0.8 3.7e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 GAT domain DUF3900 PF13039.6 ORX81807.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3900) UIM PF02809.20 ORX81807.1 - 0.0022 17.8 2.5 0.0022 17.8 2.5 2.5 3 0 0 3 3 3 1 Ubiquitin interaction motif ATP_synt_H PF05493.13 ORX81808.1 - 2.9e-25 88.5 2.2 3.4e-25 88.3 2.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 ORX81808.1 - 0.013 15.2 0.9 0.014 15.0 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MtrC PF04211.13 ORX81808.1 - 0.051 12.6 0.8 0.059 12.4 0.8 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Flavi_NS4A PF01350.17 ORX81808.1 - 0.084 12.8 0.4 0.1 12.6 0.4 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Popeye PF04831.13 ORX81808.1 - 0.12 12.6 1.6 0.14 12.3 1.6 1.1 1 0 0 1 1 1 0 Popeye protein conserved region DUF5527 PF17665.1 ORX81808.1 - 0.22 11.1 0.8 0.27 10.8 0.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5527) OppC_N PF12911.7 ORX81808.1 - 0.36 10.8 8.2 2.7 8.1 0.8 2.1 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF997 PF06196.12 ORX81808.1 - 2.6 8.1 7.5 2.3 8.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF997) FeoB_associated PF12669.7 ORX81808.1 - 4.9 7.6 8.6 7.4 7.1 0.5 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein UbiA PF01040.18 ORX81809.1 - 3.3e-58 196.9 21.7 4.2e-58 196.6 21.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family WD40 PF00400.32 ORX81810.1 - 1.8e-35 120.3 26.9 5.2e-06 27.1 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 ORX81810.1 - 1.9e-24 85.9 0.1 3.4e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 ORX81810.1 - 2.6e-07 30.9 5.0 0.0015 18.8 0.1 4.4 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX81810.1 - 0.0015 17.2 6.8 0.62 8.6 2.7 3.8 2 2 1 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 ORX81810.1 - 0.15 11.3 0.0 18 4.6 0.0 3.4 2 2 1 3 3 3 0 WD40-like domain ADIP PF11559.8 ORX81811.1 - 5.1e-29 101.3 14.0 5.1e-29 101.3 14.0 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF3037 PF11236.8 ORX81811.1 - 0.44 11.0 3.3 0.49 10.8 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) ERM PF00769.19 ORX81811.1 - 0.85 9.4 19.7 0.11 12.3 15.3 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Rootletin PF15035.6 ORX81811.1 - 8.8 6.3 22.8 0.82 9.7 4.6 3.8 2 1 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion CN_hydrolase PF00795.22 ORX81813.1 - 1.7e-62 211.1 0.0 1.9e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_4 PF13418.6 ORX81813.1 - 0.026 14.5 0.0 9.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Fasciclin PF02469.22 ORX81814.1 - 1.2e-29 103.1 0.0 3.8e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Tyrosinase PF00264.20 ORX81815.1 - 9.2e-35 120.9 4.3 1.6e-33 116.9 4.3 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase PPO1_DWL PF12142.8 ORX81815.1 - 0.033 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain SLAC1 PF03595.17 ORX81844.1 - 3e-71 240.4 45.3 3.4e-71 240.2 45.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3343 PF11823.8 ORX81844.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RBD-FIP PF09457.10 ORX81874.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 FIP domain GRP PF07172.11 ORX81876.1 - 0.71 10.6 14.3 0.74 10.5 14.3 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF562 PF04763.12 ORX81878.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF562) GRP PF07172.11 ORX81881.1 - 5.8 7.7 26.6 3.1 8.5 24.2 1.7 1 1 1 2 2 2 0 Glycine rich protein family RBD-FIP PF09457.10 ORX81883.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 FIP domain DUF4179 PF13786.6 ORX81883.1 - 0.14 12.6 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Pkinase PF00069.25 ORX81912.1 - 2.4e-73 246.8 0.0 3e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX81912.1 - 6.7e-36 123.9 0.0 8.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORX81912.1 - 3.6e-09 37.2 2.8 9.2e-09 35.9 2.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 ORX81912.1 - 2e-08 33.9 0.1 2.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORX81912.1 - 0.0012 18.5 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX81912.1 - 0.024 13.6 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORX81912.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 ORX81912.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX81912.1 - 0.16 11.8 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LAMTOR5 PF16672.5 ORX81913.1 - 4.3e-21 74.6 0.1 4.8e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 ORX81913.1 - 1.2e-05 24.9 0.1 1.4e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain PH PF00169.29 ORX81914.1 - 4.4e-05 24.0 0.1 0.002 18.6 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 ORX81914.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 PH domain DUF1624 PF07786.12 ORX81915.1 - 5.3e-09 36.0 1.1 5.3e-09 36.0 1.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 ORX81915.1 - 3.7e-08 33.2 4.4 3.7e-08 33.2 4.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) DUF2975 PF11188.8 ORX81915.1 - 0.23 11.3 6.6 0.11 12.4 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ribosom_S12_S23 PF00164.25 ORX81916.1 - 7.2e-32 109.4 0.7 1e-31 108.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Polysacc_lyase PF14099.6 ORX81949.1 - 0.0011 18.9 0.1 0.0016 18.3 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide lyase Polysacc_lyase PF14099.6 ORX81950.1 - 1.1e-06 28.7 0.1 1.6e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.11 ORX81950.1 - 0.0027 17.9 0.1 0.0051 16.9 0.1 1.7 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) Pyrid_ox_like PF16242.5 ORX81951.1 - 4.9e-29 100.8 0.1 7.1e-29 100.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ORX81951.1 - 5.2e-14 52.2 0.0 3.1e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GBP_C PF02841.14 ORX81951.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF4720 PF15846.5 ORX81952.1 - 0.097 12.5 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) BAR PF03114.18 ORX81953.1 - 3.3e-36 125.2 0.3 5.2e-36 124.5 0.3 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORX81953.1 - 1.1e-15 56.9 0.2 1.9e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX81953.1 - 1.7e-12 47.0 0.1 2.8e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX81953.1 - 4.9e-12 45.4 0.0 9e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 ORX81953.1 - 0.021 14.4 1.2 0.077 12.6 0.0 2.1 2 0 0 2 2 2 0 Arfaptin-like domain BRE1 PF08647.11 ORX81953.1 - 0.021 14.9 1.9 1.6 8.9 0.1 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 ORX81953.1 - 0.29 10.4 0.5 0.63 9.2 0.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein Thiolase_N PF00108.23 ORX81954.1 - 9.8e-23 80.8 0.0 2.4e-20 73.0 0.0 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORX81954.1 - 1.2e-10 41.1 0.0 4.1e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORX81954.1 - 8.3e-07 28.8 0.2 4.4e-05 23.3 0.2 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ORX81954.1 - 6.2e-05 22.7 0.6 0.007 16.0 0.1 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 ORX81954.1 - 0.0018 17.0 0.1 0.017 13.8 0.0 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 ORX81954.1 - 0.0075 16.3 0.0 0.18 11.9 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain G-alpha PF00503.20 ORX81955.1 - 5.4e-122 407.3 4.7 6.2e-122 407.2 4.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX81955.1 - 3.5e-15 55.9 2.2 4e-10 39.4 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORX81955.1 - 0.00017 21.4 0.1 0.00064 19.5 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORX81955.1 - 0.0012 18.3 6.4 0.0077 15.6 0.2 2.9 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORX81955.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORX81955.1 - 0.035 14.3 1.6 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 ORX81955.1 - 0.043 12.9 0.5 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 ORX81955.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ORX81955.1 - 0.12 12.4 0.0 7.7 6.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 ORX81957.1 - 4e-53 180.5 0.0 4.8e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX81957.1 - 2.1e-19 69.9 0.1 3.1e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 ORX81957.1 - 0.011 15.4 0.7 0.018 14.7 0.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pox_ser-thr_kin PF05445.11 ORX81957.1 - 0.017 14.1 0.3 0.029 13.4 0.3 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 ORX81957.1 - 0.081 12.2 0.1 11 5.2 0.0 2.4 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 ORX81957.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORX81957.1 - 0.1 12.2 0.1 0.25 10.9 0.1 1.6 1 1 1 2 2 2 0 RIO1 family ABC1 PF03109.16 ORX81957.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 ORX81957.1 - 0.19 11.3 0.6 0.41 10.2 0.4 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Polysacc_deac_1 PF01522.21 ORX81958.1 - 1.1e-32 112.5 0.0 2.6e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase LRR_4 PF12799.7 ORX81959.1 - 1.7e-06 28.2 2.4 0.002 18.5 0.1 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORX81959.1 - 2.4e-05 24.0 0.5 3.5 7.9 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 ORX81959.1 - 0.001 19.3 3.9 2.5 9.0 0.3 3.5 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.6 ORX81959.1 - 0.0095 15.7 0.3 0.22 11.3 0.3 2.6 1 1 1 2 2 2 1 Leucine rich repeat UPF0731 PF14982.6 ORX81959.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 UPF0731 family Pentapeptide PF00805.22 ORX81959.1 - 0.17 11.6 0.1 7.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Gti1_Pac2 PF09729.9 ORX81960.1 - 1.8e-39 135.7 0.8 1e-35 123.5 0.1 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family ThiF PF00899.21 ORX81993.1 - 1.9e-112 374.6 0.0 9e-74 247.9 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 ORX81993.1 - 2.2e-96 322.7 0.2 2.2e-96 322.7 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ORX81993.1 - 3.1e-36 123.9 0.2 7.3e-36 122.8 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 ORX81993.1 - 1.2e-35 121.5 0.3 3.5e-35 120.0 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ORX81993.1 - 1.8e-26 92.1 0.6 4.4e-26 90.9 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle zf-MYND PF01753.18 ORX81995.1 - 7.3e-08 32.4 16.3 1.5e-07 31.4 16.3 1.6 1 0 0 1 1 1 1 MYND finger Aminotran_3 PF00202.21 ORX81996.1 - 2.1e-116 388.9 0.0 2.4e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX81996.1 - 0.0006 19.1 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Serine_rich PF08824.10 ORX81996.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain PHD PF00628.29 ORX81998.1 - 4.7e-08 32.8 15.9 9.8e-08 31.8 15.9 1.6 1 0 0 1 1 1 1 PHD-finger CarbpepA_inh PF02977.15 ORX81998.1 - 0.036 13.8 2.9 1.6 8.6 0.4 2.5 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Topoisom_bac PF01131.20 ORX81999.1 - 1.4e-109 366.9 0.0 1.7e-109 366.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 ORX81999.1 - 1.2e-19 70.5 0.0 2.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.12 ORX81999.1 - 1.3e-14 54.0 6.1 3.4e-14 52.7 6.1 1.8 1 0 0 1 1 1 1 GRF zinc finger Ceramidase_alk PF04734.13 ORX82000.1 - 6.8e-224 744.2 0.0 8.1e-224 743.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ORX82000.1 - 5.3e-53 179.3 0.2 8.6e-53 178.6 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal MG2 PF01835.19 ORX82000.1 - 0.081 13.4 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 MG2 domain DUF1775 PF07987.11 ORX82000.1 - 0.15 12.3 0.3 0.3 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Arrestin_C PF02752.22 ORX82001.1 - 4.5e-06 27.1 0.9 9.7e-06 26.1 0.2 1.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX82001.1 - 0.06 13.4 0.1 0.19 11.8 0.1 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain MOEP19 PF16005.5 ORX82001.1 - 0.14 12.1 0.3 0.38 10.8 0.1 1.8 2 0 0 2 2 2 0 KH-like RNA-binding domain DUF4348 PF14254.6 ORX82001.1 - 0.15 11.4 0.1 0.59 9.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4348) MFS_1 PF07690.16 ORX82002.1 - 1.8e-47 162.0 39.8 2.8e-47 161.4 39.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX82002.1 - 7e-16 57.8 17.3 9e-16 57.4 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX82002.1 - 2e-13 50.0 12.7 1e-12 47.7 3.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ORX82002.1 - 4.9e-10 38.6 22.2 4.6e-06 25.5 3.1 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORX82002.1 - 1.6e-05 23.9 7.9 1.6e-05 23.9 7.9 2.5 2 1 0 2 2 2 1 MFS_1 like family Transp_inhibit PF18791.1 ORX82002.1 - 0.036 13.6 0.9 0.086 12.4 0.2 1.9 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain PetL PF05115.14 ORX82002.1 - 5.9 7.0 11.6 2.2 8.3 0.7 3.3 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) START PF01852.19 ORX82036.1 - 2.7e-21 76.0 0.0 4.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 ORX82036.1 - 0.064 13.5 0.0 1 9.6 0.0 2.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RFX_DNA_binding PF02257.15 ORX82037.1 - 6.8e-10 39.4 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain BOFC_N PF08977.10 ORX82037.1 - 0.003 17.5 0.1 0.0071 16.3 0.1 1.5 1 0 0 1 1 1 1 Bypass of Forespore C, N terminal Pox_D5 PF03288.16 ORX82037.1 - 0.019 15.5 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like NMD3 PF04981.13 ORX82038.1 - 8.6e-81 271.0 7.2 1.2e-80 270.5 7.2 1.2 1 0 0 1 1 1 1 NMD3 family Oxidored_q6 PF01058.22 ORX82039.1 - 5.8e-23 81.1 0.3 8e-23 80.7 0.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit p450 PF00067.22 ORX82040.1 - 1.3e-84 284.6 0.2 1.5e-84 284.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rit1_C PF17184.4 ORX82041.1 - 9.3e-99 330.3 0.0 1.4e-98 329.7 0.0 1.3 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 ORX82041.1 - 7.5e-30 103.5 0.0 1.6e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain DSPc PF00782.20 ORX82041.1 - 2.9e-08 33.6 0.0 9.6e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ORX82041.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 ORX82041.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 ORX82041.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FtsX_ECD PF18075.1 ORX82041.1 - 0.15 12.7 0.4 0.3 11.7 0.4 1.5 1 0 0 1 1 1 0 FtsX extracellular domain Alpha-amylase PF00128.24 ORX82042.1 - 4.7e-29 102.0 7.6 1.7e-28 100.2 7.6 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 ORX82042.1 - 4.7e-11 41.6 0.8 0.00097 17.5 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 ORX82042.1 - 1.9e-09 37.6 0.1 5.8e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) GAF PF01590.26 ORX82043.1 - 0.029 15.0 0.0 0.075 13.7 0.0 1.8 1 1 0 1 1 1 0 GAF domain GAF PF01590.26 ORX82044.1 - 0.025 15.2 0.0 0.07 13.8 0.0 1.8 1 1 0 1 1 1 0 GAF domain zf-RanBP PF00641.18 ORX82045.1 - 1.8e-06 27.2 9.0 3.4e-06 26.3 9.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Desulfoferrod_N PF06397.12 ORX82045.1 - 0.26 10.9 0.4 0.57 9.9 0.4 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-Sec23_Sec24 PF04810.15 ORX82045.1 - 0.74 9.9 8.4 0.48 10.5 1.6 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger DUF727 PF05303.12 ORX82046.1 - 0.0028 17.7 0.0 0.0056 16.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Chs7 PF12271.8 ORX82079.1 - 4.6e-107 357.7 21.4 5.2e-107 357.5 21.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Connexin PF00029.19 ORX82079.1 - 0.065 13.0 2.0 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 Connexin PEX11 PF05648.14 ORX82080.1 - 5.9e-26 91.3 0.1 6.2e-25 88.0 0.1 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RRM_1 PF00076.22 ORX82081.1 - 3.1e-57 190.3 0.0 4.9e-20 71.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX82081.1 - 2.3e-09 36.9 0.0 0.00039 20.0 0.0 3.2 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX82081.1 - 2.1e-06 27.5 0.0 0.00018 21.3 0.0 3.0 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX82081.1 - 0.0043 17.1 0.1 0.35 11.0 0.0 3.6 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ORX82081.1 - 0.091 12.8 0.4 51 4.0 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Ribosomal_S7 PF00177.21 ORX82082.1 - 2.5e-37 127.8 1.0 3e-37 127.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Arm PF00514.23 ORX82083.1 - 1.7e-76 250.2 26.3 2e-12 46.7 0.1 11.3 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORX82083.1 - 8.6e-21 74.0 9.7 0.0027 18.2 0.1 8.5 6 3 3 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 ORX82083.1 - 2.2e-20 72.8 6.9 0.0023 18.3 0.1 7.7 2 2 5 8 8 8 7 HEAT repeats HEAT PF02985.22 ORX82083.1 - 2.7e-18 64.5 12.8 0.16 12.3 0.0 9.6 10 0 0 10 10 10 5 HEAT repeat KAP PF05804.12 ORX82083.1 - 5.5e-12 44.7 1.5 8.4e-12 44.1 1.5 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 ORX82083.1 - 6.6e-12 44.8 9.6 1.2e-08 34.0 0.7 3.0 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 ORX82083.1 - 1e-08 34.9 6.5 0.00099 18.5 0.3 3.5 1 1 2 3 3 3 3 V-ATPase subunit H Arm_2 PF04826.13 ORX82083.1 - 2.8e-08 33.6 9.8 5.5e-06 26.0 3.7 2.6 1 1 2 3 3 3 3 Armadillo-like Cnd1 PF12717.7 ORX82083.1 - 4.5e-08 33.3 10.7 0.11 12.5 1.3 4.9 3 1 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORX82083.1 - 0.00061 20.3 0.1 0.6 10.7 0.1 4.0 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 ORX82083.1 - 0.00083 19.8 6.6 5.8 7.9 0.0 6.7 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat DUF3361 PF11841.8 ORX82083.1 - 0.0022 18.0 12.5 0.42 10.5 0.0 5.1 2 1 4 6 6 6 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 ORX82083.1 - 0.017 15.3 3.9 0.72 10.1 0.0 4.2 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 ORX82083.1 - 0.15 12.1 3.7 2.4 8.2 0.3 4.2 3 1 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain NGP1NT PF08153.12 ORX82084.1 - 2.5e-54 182.9 0.1 2.5e-54 182.9 0.1 2.5 2 1 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 ORX82084.1 - 3.5e-17 62.5 0.1 1.4e-13 50.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX82084.1 - 7.3e-06 25.6 0.2 5.1e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 ORX82084.1 - 0.00015 21.3 0.2 0.038 13.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX82084.1 - 0.00026 20.9 0.0 0.00077 19.4 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 ORX82084.1 - 0.032 14.5 2.4 3.6 7.8 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MCR_C PF04609.12 ORX82084.1 - 0.083 12.0 1.2 0.096 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C NDK PF00334.19 ORX82084.1 - 0.1 12.6 0.6 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoside diphosphate kinase Dynamin_N PF00350.23 ORX82084.1 - 3.4 7.7 19.1 1.4 8.9 0.0 5.0 3 3 1 4 4 4 0 Dynamin family RNA_pol_Rpb8 PF03870.15 ORX82085.1 - 1e-53 181.2 1.7 1.2e-53 181.1 1.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 ORX82085.1 - 0.0036 17.3 0.2 0.57 10.2 0.2 2.1 1 1 1 2 2 2 2 DNA-directed RNA polymerase, subunit G Ribosomal_L37ae PF01780.19 ORX82086.1 - 1.8e-41 140.1 11.2 2.2e-41 139.8 11.2 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORX82086.1 - 0.0089 16.1 1.6 0.014 15.5 1.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORX82086.1 - 0.034 14.1 2.3 0.062 13.3 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORX82086.1 - 0.14 12.2 3.7 4 7.6 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger P2X_receptor PF00864.19 ORX82087.1 - 2.2e-07 30.3 0.1 4.4e-07 29.3 0.0 1.4 2 0 0 2 2 2 1 ATP P2X receptor HemY_N PF07219.13 ORX82087.1 - 0.02 15.1 1.2 0.034 14.3 1.2 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Minor_capsid_1 PF10665.9 ORX82087.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein Cyclin PF08613.11 ORX82088.1 - 2.2e-08 34.6 0.0 2.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX82088.1 - 0.0011 18.7 0.3 0.0019 18.0 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SMP_C2CD2L PF18696.1 ORX82088.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Synaptotagmin-like, mitochondrial and lipid-binding domain EF-hand_4 PF12763.7 ORX82089.1 - 5.3e-32 109.9 1.3 1.1e-16 60.6 0.0 3.4 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORX82089.1 - 2.6e-11 42.2 0.1 0.0096 15.4 0.0 4.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 ORX82089.1 - 1.6e-09 38.1 0.0 1.5e-05 25.3 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain pair UBA PF00627.31 ORX82089.1 - 1e-06 28.5 0.1 1e-06 28.5 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_6 PF13405.6 ORX82089.1 - 1.7e-06 27.4 0.2 0.24 11.4 0.1 4.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 ORX82089.1 - 2.9e-05 23.8 0.2 3.5 7.5 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair DUF4201 PF13870.6 ORX82089.1 - 0.052 13.3 35.1 0.038 13.7 23.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF3584 PF12128.8 ORX82089.1 - 0.15 9.6 35.3 0.21 9.1 35.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 ORX82089.1 - 0.23 12.0 51.5 0.067 13.7 23.3 3.6 1 1 2 3 3 3 0 Apg6 coiled-coil region SHE3 PF17078.5 ORX82089.1 - 0.37 10.5 34.6 0.17 11.6 18.1 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 ORX82089.1 - 0.62 9.4 39.0 1.7 7.9 26.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EF-hand_5 PF13202.6 ORX82089.1 - 0.88 9.2 0.0 0.88 9.2 0.0 4.0 4 0 0 4 4 4 0 EF hand TMF_TATA_bd PF12325.8 ORX82089.1 - 1.4 9.1 43.0 0.062 13.5 6.5 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 ORX82089.1 - 3.5 7.7 58.3 0.27 11.3 34.1 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein FapA PF03961.13 ORX82089.1 - 4.2 5.9 32.0 0.34 9.5 16.2 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 ORX82089.1 - 9.9 4.9 48.6 6.4 5.5 11.3 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein RRM_1 PF00076.22 ORX82090.1 - 4.3e-15 55.3 0.0 8.4e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX82090.1 - 0.022 14.7 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4011 PF13195.6 ORX82090.1 - 0.045 13.7 3.0 0.35 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) RRM_5 PF13893.6 ORX82090.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ORX82090.1 - 0.18 12.0 3.1 0.33 11.2 0.1 2.7 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Dermcidin PF15291.6 ORX82090.1 - 7.6 7.2 8.2 39 4.9 3.0 2.5 2 1 0 2 2 2 0 Dermcidin, antibiotic peptide Voltage_CLC PF00654.20 ORX82091.1 - 2.4e-95 319.8 15.4 2.4e-95 319.8 15.4 2.4 2 1 1 3 3 3 1 Voltage gated chloride channel CBS PF00571.28 ORX82091.1 - 1.7e-10 41.2 0.1 2.4e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain GAPES1 PF17155.4 ORX82091.1 - 0.035 13.4 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Abhydrolase_1 PF00561.20 ORX82092.1 - 5e-18 65.7 0.2 8.9e-18 64.9 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX82092.1 - 2.3e-15 57.8 0.0 3.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX82092.1 - 9.3e-08 31.6 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 ORX82092.1 - 1.6e-05 25.3 0.1 6.1e-05 23.4 0.0 2.0 3 0 0 3 3 3 1 Epoxide hydrolase N terminus AXE1 PF05448.12 ORX82092.1 - 0.002 16.9 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_M57 PF12388.8 ORX82092.1 - 0.022 14.4 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF5010 PF16402.5 ORX82092.1 - 0.027 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Lipase_2 PF01674.18 ORX82092.1 - 0.15 11.6 0.4 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) Raf1_HTH PF18579.1 ORX82092.1 - 0.17 11.6 0.1 0.46 10.2 0.1 1.6 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Glyco_hydro_25 PF01183.20 ORX82093.1 - 2.4e-48 164.7 0.4 2.7e-48 164.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Condensation PF00668.20 ORX82118.1 - 0 1363.7 0.0 8.5e-116 387.3 0.0 5.2 5 0 0 5 5 5 5 Condensation domain AMP-binding PF00501.28 ORX82118.1 - 0 1159.5 0.0 4.8e-98 328.5 0.0 7.3 4 2 2 6 6 6 6 AMP-binding enzyme AMP-binding_C PF13193.6 ORX82118.1 - 7.2e-56 187.1 0.6 5.6e-12 46.5 0.0 5.1 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX82118.1 - 3.4e-49 165.1 1.8 1e-10 41.8 0.1 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site GAPES4 PF17157.4 ORX82118.1 - 9.7e-07 29.1 0.0 5.7 7.4 0.0 4.8 4 0 0 4 4 4 2 Gammaproteobacterial periplasmic sensor domain DUF1398 PF07166.11 ORX82118.1 - 0.004 17.2 0.0 35 4.5 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1398) FTP PF07504.13 ORX82118.1 - 0.018 14.8 0.0 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif PurL_C PF16904.5 ORX82118.1 - 0.27 11.6 2.2 1.2e+02 3.1 0.1 3.8 3 0 0 3 3 3 0 Phosphoribosylformylglycinamidine synthase II C-terminus HAD_2 PF13419.6 ORX82120.1 - 3.3e-26 92.5 0.0 4.4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX82120.1 - 2.5e-19 70.4 0.1 6.2e-17 62.6 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX82120.1 - 1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORX82120.1 - 0.00014 22.3 0.0 0.00019 21.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 ORX82120.1 - 0.0061 16.2 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Death PF00531.22 ORX82120.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Death domain Hydrolase_6 PF13344.6 ORX82120.1 - 0.11 12.6 0.0 1.6 8.9 0.0 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Alpha-amylase PF00128.24 ORX82122.1 - 3.9e-26 92.4 4.7 1.3e-25 90.7 4.7 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 ORX82122.1 - 2e-05 24.6 0.0 0.00033 20.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 ORX82122.1 - 0.0017 16.7 0.1 0.42 8.7 0.1 2.7 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 Myb_DNA-bind_4 PF13837.6 ORX82125.1 - 1.2e-16 60.9 1.3 1.7e-16 60.4 1.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX82125.1 - 5.2e-08 33.0 0.4 8.8e-08 32.2 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX82125.1 - 1.7e-07 31.3 0.6 2.6e-07 30.8 0.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX82125.1 - 0.0002 21.6 0.5 0.00039 20.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like DMAP_binding PF06464.11 ORX82125.1 - 0.0028 18.5 2.8 0.0038 18.0 2.8 1.1 1 0 0 1 1 1 1 DMAP1-binding Domain Myb_DNA-bind_5 PF13873.6 ORX82125.1 - 0.0044 17.1 2.8 0.0046 17.0 0.8 2.1 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORX82125.1 - 0.016 16.1 0.6 0.026 15.5 0.6 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF1647 PF07801.11 ORX82158.1 - 0.0058 16.4 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Glycos_transf_2 PF00535.26 ORX82158.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Tropomyosin_1 PF12718.7 ORX82159.1 - 2.6e-38 131.4 31.8 3.3e-38 131.0 31.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 ORX82159.1 - 1.1e-16 60.9 32.3 1.9e-08 34.0 9.6 2.4 1 1 0 2 2 2 2 Tropomyosin EzrA PF06160.12 ORX82159.1 - 3e-05 22.4 26.5 0.0056 14.9 14.2 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 ORX82159.1 - 0.00054 20.0 35.3 0.00084 19.4 32.7 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 ORX82159.1 - 0.0018 17.5 26.7 0.012 14.8 2.5 2.7 1 1 2 3 3 3 1 Myosin-like coiled-coil protein Vps5 PF09325.10 ORX82159.1 - 0.0021 17.6 16.5 0.04 13.5 6.4 3.0 2 1 1 3 3 3 1 Vps5 C terminal like Fib_alpha PF08702.10 ORX82159.1 - 0.0028 17.9 18.7 0.027 14.7 2.9 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family DHR10 PF18595.1 ORX82159.1 - 0.0033 17.5 36.7 0.044 13.9 10.9 2.6 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain DUF3450 PF11932.8 ORX82159.1 - 0.0046 16.3 26.8 0.0085 15.4 14.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) DUF1664 PF07889.12 ORX82159.1 - 0.0092 16.0 16.8 0.03 14.4 7.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 ORX82159.1 - 0.012 14.5 32.5 0.19 10.6 18.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 ORX82159.1 - 0.017 15.1 7.8 0.017 15.1 7.8 3.4 1 1 1 2 2 1 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 ORX82159.1 - 0.019 15.0 19.9 0.046 13.7 8.0 2.2 1 1 1 2 2 2 0 Laminin Domain II BRE1 PF08647.11 ORX82159.1 - 0.019 15.0 11.1 0.019 15.0 11.1 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 ORX82159.1 - 0.02 15.3 19.8 0.78 10.2 1.8 4.3 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) HalX PF08663.10 ORX82159.1 - 0.022 15.0 24.2 1.1 9.7 0.1 4.4 1 1 3 4 4 4 0 HalX domain Seryl_tRNA_N PF02403.22 ORX82159.1 - 0.028 14.7 28.6 0.7 10.1 3.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 ORX82159.1 - 0.03 14.4 3.6 0.03 14.4 3.6 4.2 1 1 3 4 4 3 0 bZIP transcription factor DUF3584 PF12128.8 ORX82159.1 - 0.03 11.9 26.4 0.036 11.6 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin PF02996.17 ORX82159.1 - 0.062 13.2 25.9 0.15 12.0 0.7 4.0 1 1 3 4 4 4 0 Prefoldin subunit GAS PF13851.6 ORX82159.1 - 0.065 12.6 32.3 0.63 9.4 4.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 ORX82159.1 - 0.067 13.1 33.1 2.5 8.1 6.9 4.1 1 1 1 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 ORX82159.1 - 0.069 13.2 34.3 1.1 9.4 8.0 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 ORX82159.1 - 0.078 13.1 29.3 0.8 9.8 4.2 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 ORX82159.1 - 0.095 13.1 33.1 1.4 9.4 8.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GIT_CC PF16559.5 ORX82159.1 - 0.13 12.2 11.9 1.3 8.9 2.6 2.8 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fez1 PF06818.15 ORX82159.1 - 0.14 12.6 27.3 3.2 8.2 7.8 2.1 1 1 1 2 2 2 0 Fez1 DUF724 PF05266.14 ORX82159.1 - 0.15 11.9 24.5 0.55 10.0 12.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Alanine_zipper PF11839.8 ORX82159.1 - 0.15 12.4 9.3 0.46 10.9 1.8 3.3 3 1 1 4 4 3 0 Alanine-zipper, major outer membrane lipoprotein ATG16 PF08614.11 ORX82159.1 - 0.16 12.2 32.3 10 6.3 18.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HR1 PF02185.16 ORX82159.1 - 0.2 11.8 28.2 1 9.5 4.7 3.8 1 1 2 3 3 3 0 Hr1 repeat HrpB7 PF09486.10 ORX82159.1 - 0.2 12.0 21.6 0.28 11.6 6.1 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Nsp1_C PF05064.13 ORX82159.1 - 0.23 11.3 20.3 0.51 10.2 9.6 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region IFT57 PF10498.9 ORX82159.1 - 0.25 10.3 22.1 0.17 10.8 13.4 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ERM PF00769.19 ORX82159.1 - 0.26 11.1 33.0 0.69 9.7 32.7 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 ORX82159.1 - 0.32 11.1 32.4 0.44 10.6 19.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ORX82159.1 - 0.59 10.7 38.7 9.4e+02 0.3 37.6 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 ORX82159.1 - 0.6 8.6 25.3 1.2 7.7 11.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 ORX82159.1 - 0.64 10.4 33.2 0.78 10.1 15.7 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Dynamitin PF04912.14 ORX82159.1 - 0.72 9.1 24.4 2.2 7.5 24.4 1.9 1 1 0 1 1 1 0 Dynamitin CREPT PF16566.5 ORX82159.1 - 0.76 9.9 22.1 1.3 9.2 13.3 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ABC_tran_CTD PF16326.5 ORX82159.1 - 0.88 9.9 32.3 0.79 10.0 11.2 3.7 1 1 3 4 4 4 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 ORX82159.1 - 0.91 9.7 32.8 9.9 6.4 25.8 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF5082 PF16888.5 ORX82159.1 - 1.1 9.5 23.0 3.6 7.9 9.6 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) HemX PF04375.14 ORX82159.1 - 1.3 8.3 22.6 0.83 8.9 4.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Nup54 PF13874.6 ORX82159.1 - 1.4 9.0 20.4 3.8 7.6 9.2 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.12 ORX82159.1 - 1.5 9.5 23.8 0.71 10.5 4.2 3.5 1 1 3 4 4 4 0 SlyX DUF16 PF01519.16 ORX82159.1 - 1.5 9.3 22.3 8.4 6.9 8.3 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 CLZ PF16526.5 ORX82159.1 - 1.6 9.2 28.1 3 8.3 10.2 3.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 ORX82159.1 - 1.9 7.7 22.9 1e+02 2.0 22.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 ORX82159.1 - 2.1 7.9 25.4 3.7 7.1 21.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) HOOK PF05622.12 ORX82159.1 - 2.5 6.1 29.9 3.4 5.7 29.9 1.2 1 0 0 1 1 1 0 HOOK protein BST2 PF16716.5 ORX82159.1 - 2.7 8.6 27.4 0.33 11.6 3.5 2.7 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 YscO PF07321.12 ORX82159.1 - 3.4 7.6 31.3 0.39 10.7 11.3 3.1 1 1 2 3 3 3 0 Type III secretion protein YscO CCDC-167 PF15188.6 ORX82159.1 - 3.5 8.0 29.0 0.96 9.8 10.8 3.2 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Sec34 PF04136.15 ORX82159.1 - 3.5 7.5 16.2 5 7.0 7.2 2.8 2 1 1 3 3 3 0 Sec34-like family FH2 PF02181.23 ORX82159.1 - 3.8 6.5 17.5 2.1 7.4 8.2 2.0 1 1 0 2 2 2 0 Formin Homology 2 Domain DUF5320 PF17253.2 ORX82159.1 - 3.8 8.6 21.9 4.3 8.5 2.5 3.8 1 1 2 3 3 3 0 Family of unknown function (DUF5320) Occludin_ELL PF07303.13 ORX82159.1 - 4.1 8.2 16.0 3.6 8.4 1.2 2.7 2 1 1 3 3 3 0 Occludin homology domain TMPIT PF07851.13 ORX82159.1 - 4.5 6.4 19.6 4.1 6.5 3.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein Rootletin PF15035.6 ORX82159.1 - 5 7.1 27.2 0.44 10.5 16.4 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CC2-LZ PF16516.5 ORX82159.1 - 5.3 7.5 26.0 3.4 8.1 5.3 3.8 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HMMR_N PF15905.5 ORX82159.1 - 5.3 6.4 32.5 3.4 7.1 9.2 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal WXG100 PF06013.12 ORX82159.1 - 5.4 7.3 10.6 22 5.4 0.1 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG XhlA PF10779.9 ORX82159.1 - 5.4 7.3 28.9 0.87 9.8 1.1 4.2 1 1 4 6 6 6 0 Haemolysin XhlA DUF262 PF03235.14 ORX82159.1 - 5.7 7.1 10.7 7.3 6.7 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 Cep57_CLD_2 PF14197.6 ORX82159.1 - 7.2 6.8 33.3 0.56 10.3 1.9 3.4 1 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Cortex-I_coil PF09304.10 ORX82159.1 - 7.8 6.8 26.2 10 6.4 4.6 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Allexi_40kDa PF05549.11 ORX82159.1 - 8.7 5.8 15.0 3.9 6.9 6.1 2.2 1 1 2 3 3 3 0 Allexivirus 40kDa protein SNARE PF05739.19 ORX82159.1 - 9.2 6.4 12.1 3.3 7.8 1.6 3.0 4 0 0 4 4 2 0 SNARE domain Csm1_N PF18504.1 ORX82159.1 - 9.3 6.7 30.4 1.2 9.5 2.5 4.3 1 1 3 4 4 3 0 Csm1 N-terminal domain WDCP PF15390.6 ORX82159.1 - 9.7 4.4 11.2 11 4.3 11.2 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AAA_13 PF13166.6 ORX82159.1 - 10 4.6 24.0 5.6 5.5 6.8 1.9 1 1 1 2 2 2 0 AAA domain INSIG PF07281.12 ORX82160.1 - 1.3e-18 67.5 7.8 8e-17 61.6 7.8 2.3 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF4118 PF13493.6 ORX82160.1 - 2.9 7.7 9.8 3.4 7.5 2.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) E1_dh PF00676.20 ORX82161.1 - 1.9e-119 398.1 0.0 2.2e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORX82161.1 - 0.0089 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 ORX82161.1 - 0.0091 16.9 1.7 1.8 9.6 0.2 3.0 2 1 0 2 2 2 2 KRTAP type 7 family HIT PF01230.23 ORX82162.1 - 1.5e-24 86.5 2.0 2.1e-24 86.1 1.5 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 ORX82162.1 - 2.8e-13 50.3 0.9 3.4e-13 50.1 0.5 1.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORX82162.1 - 1.6e-07 31.2 0.2 2.4e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rhodanese PF00581.20 ORX82163.1 - 2.5e-14 53.7 0.0 3.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF4930 PF16284.5 ORX82163.1 - 0.25 11.3 0.0 0.39 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) Rap_GAP PF02145.15 ORX82164.1 - 1.8e-46 158.0 0.0 3.7e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Imm42 PF15593.6 ORX82164.1 - 3.4 8.1 5.0 1.3 9.5 0.2 2.7 3 0 0 3 3 3 0 Immunity protein 42 Lipoprotein_3 PF00938.17 ORX82165.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein DUF1282 PF06930.12 ORX82166.1 - 0.22 11.3 3.8 0.36 10.6 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Thioredoxin PF00085.20 ORX82201.1 - 2e-35 120.9 1.6 7e-24 83.8 0.5 3.5 3 1 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 ORX82201.1 - 2.1e-10 40.8 1.0 3.1e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 ORX82201.1 - 2.8e-10 40.6 0.8 3.1e-05 24.4 0.2 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ORX82201.1 - 1.4e-07 31.2 1.8 0.0044 16.4 0.1 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORX82201.1 - 1.7e-07 31.4 2.5 0.005 17.1 0.1 4.3 3 2 1 4 4 4 2 Thioredoxin-like HyaE PF07449.11 ORX82201.1 - 0.00022 21.1 0.0 0.048 13.6 0.0 2.7 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 ORX82201.1 - 0.0019 18.1 0.2 0.0053 16.7 0.1 1.8 2 0 0 2 2 2 1 AhpC/TSA family TraF PF13728.6 ORX82201.1 - 0.0038 17.1 8.6 0.0075 16.1 0.1 3.6 3 2 1 4 4 4 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ORX82201.1 - 0.0043 16.8 0.2 0.2 11.4 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.6 ORX82201.1 - 0.015 15.4 0.2 1 9.5 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 ORX82201.1 - 0.13 12.4 0.1 0.47 10.7 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 ORX82201.1 - 0.15 11.8 0.4 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 Redoxin Cyclin PF08613.11 ORX82202.1 - 2.3e-19 70.3 0.7 2.7e-19 70.1 0.7 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX82202.1 - 3.5e-10 39.7 0.2 4.4e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 ORX82203.1 - 1e-66 225.1 5.8 1e-66 225.1 5.8 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX82203.1 - 1.3e-42 144.5 0.2 8e-42 142.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORX82203.1 - 6.8e-21 74.6 13.6 7.2e-19 68.1 2.1 4.1 4 1 2 6 6 5 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX82203.1 - 5.9e-12 45.5 4.5 2.2e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX82203.1 - 2e-11 43.9 1.1 2e-11 43.9 1.1 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 ORX82203.1 - 1e-09 38.0 10.6 2.7e-09 36.6 3.1 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORX82203.1 - 6.1e-09 36.0 2.7 4e-05 23.8 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORX82203.1 - 3.9e-08 32.8 2.7 3.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 ORX82203.1 - 1e-07 31.0 13.3 9.2e-05 21.3 1.2 4.1 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 ORX82203.1 - 1.7e-07 30.7 2.2 1.7e-07 30.7 2.2 3.4 3 1 1 4 4 4 1 FAD binding domain K_oxygenase PF13434.6 ORX82203.1 - 1.8e-06 27.4 0.1 0.0013 17.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ORX82203.1 - 0.00012 21.5 10.6 0.01 15.2 1.0 3.3 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORX82203.1 - 0.00043 19.6 10.5 0.014 14.7 1.0 3.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 ORX82203.1 - 0.00063 19.4 12.7 0.12 11.9 0.3 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ORX82203.1 - 0.075 13.5 1.3 4.1 7.9 0.1 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORX82203.1 - 0.5 9.4 4.8 0.36 9.8 0.4 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 ORX82203.1 - 2.5 8.0 6.5 0.41 10.5 0.6 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bac_globin PF01152.21 ORX82230.1 - 8.2e-12 45.3 0.1 9.9e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX82230.1 - 0.00039 20.3 0.1 0.001 19.0 0.1 1.6 1 1 1 2 2 2 1 Protoglobin DUF4890 PF16231.5 ORX82230.1 - 0.099 13.1 0.6 0.24 11.9 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4890) Peptidase_M16_C PF05193.21 ORX82230.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Peptidase M16 inactive domain HMG_box PF00505.19 ORX82231.1 - 6.1e-22 77.8 1.0 8.7e-22 77.3 1.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX82231.1 - 1.2e-09 38.6 1.5 1.6e-09 38.2 1.5 1.2 1 0 0 1 1 1 1 HMG-box domain DUF1796 PF08795.10 ORX82231.1 - 0.068 13.1 0.0 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) KORA PF16509.5 ORX82231.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Iso_dh PF00180.20 ORX82232.1 - 2.7e-78 263.6 0.0 3.4e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ANTH PF07651.16 ORX82233.1 - 3e-69 233.1 4.8 3.3e-69 233.0 0.0 2.9 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 ORX82233.1 - 3.6e-45 153.9 11.6 3.6e-45 153.9 11.6 6.2 4 1 2 6 6 6 2 I/LWEQ domain TcdB_N PF12918.7 ORX82233.1 - 0.72 10.2 7.6 0.2 11.9 0.4 3.1 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF2935 PF11155.8 ORX82233.1 - 1 9.7 7.9 1.1e+02 3.2 0.8 5.5 3 3 1 4 4 4 0 Domain of unknown function (DUF2935) HMG_box PF00505.19 ORX82235.1 - 2.2e-24 85.6 1.7 4.1e-24 84.8 1.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX82235.1 - 5.4e-12 46.1 1.7 5.7e-11 42.9 2.1 2.1 2 0 0 2 2 2 1 HMG-box domain Protamine_like PF06382.11 ORX82235.1 - 0.0046 17.1 0.2 0.0077 16.4 0.2 1.3 1 0 0 1 1 1 1 Protamine and protamine like HTH_24 PF13412.6 ORX82235.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RRM_1 PF00076.22 ORX82237.1 - 3.3e-16 58.9 0.0 4.7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 ORX82237.1 - 2.9e-13 49.2 16.6 3e-07 30.2 3.6 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 ORX82237.1 - 0.00085 19.0 7.6 0.16 11.8 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle RRM_5 PF13893.6 ORX82237.1 - 0.004 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ORX82237.1 - 0.0077 16.2 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 DbpA RNA binding domain zf-CCHC_2 PF13696.6 ORX82237.1 - 0.02 14.7 8.9 0.02 14.7 1.5 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORX82237.1 - 0.028 14.1 11.9 0.25 11.1 2.6 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RRM_occluded PF16842.5 ORX82237.1 - 0.031 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ntox16 PF15523.6 ORX82237.1 - 0.097 12.9 4.1 6.1 7.1 0.3 2.3 2 0 0 2 2 2 0 Novel toxin 16 Nup35_RRM_2 PF14605.6 ORX82237.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.6 ORX82237.1 - 1.7 8.7 10.5 3.4 7.7 1.1 3.0 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 ORX82237.1 - 6.4 6.7 13.7 1.9 8.4 2.5 2.5 2 0 0 2 2 2 0 Zinc knuckle PSS PF03034.15 ORX82238.1 - 2.3e-118 394.9 20.0 3.4e-118 394.3 20.0 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase Ribosomal_S19 PF00203.21 ORX82239.1 - 1.5e-36 124.1 1.0 2.1e-36 123.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 ORX82240.1 - 1.6e-26 92.7 13.9 1.8e-26 92.5 13.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rnk_N PF14760.6 ORX82240.1 - 0.55 10.8 0.4 0.55 10.8 0.4 2.6 3 1 0 3 3 3 0 Rnk N-terminus Nop52 PF05997.12 ORX82241.1 - 4e-75 252.3 3.6 4e-75 252.3 3.6 2.3 2 1 0 2 2 2 1 Nucleolar protein,Nop52 HEAT PF02985.22 ORX82241.1 - 0.16 12.3 0.0 0.93 9.9 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat TAN PF11640.8 ORX82241.1 - 0.72 10.0 6.3 11 6.2 2.7 3.0 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Nuc_sug_transp PF04142.15 ORX82243.1 - 2e-108 362.3 17.9 2.3e-108 362.1 17.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORX82243.1 - 2.6e-07 30.1 16.6 4.2e-07 29.5 16.6 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.6 ORX82243.1 - 0.00012 21.8 3.9 0.00019 21.1 3.9 1.5 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter EamA PF00892.20 ORX82243.1 - 0.00068 19.8 4.7 0.00068 19.8 4.7 2.3 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORX82243.1 - 0.0034 16.6 19.0 0.0058 15.9 19.0 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 ORX82243.1 - 1 8.6 14.7 0.34 10.2 0.9 1.7 1 1 1 2 2 2 0 Triose-phosphate Transporter family Ribosomal_L26 PF16906.5 ORX82244.1 - 2.8e-37 127.1 3.9 3.7e-37 126.7 3.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORX82244.1 - 6.9e-10 38.5 1.1 6.9e-10 38.5 1.1 1.8 2 0 0 2 2 2 1 KOW motif ChaC PF04752.12 ORX82245.1 - 1.4e-57 194.7 0.0 1.6e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein SPT2 PF08243.11 ORX82246.1 - 6.2e-19 68.6 12.7 6.2e-19 68.6 12.7 3.8 3 1 0 3 3 3 1 SPT2 chromatin protein Pkinase PF00069.25 ORX82247.1 - 1.6e-52 178.5 0.0 2.2e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX82247.1 - 1.8e-22 79.9 0.0 2.5e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX82247.1 - 8.3e-05 22.0 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX82247.1 - 0.002 17.1 0.1 0.18 10.7 0.0 2.2 1 1 1 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 ORX82247.1 - 0.004 16.8 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORX82247.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORX82248.1 - 7.3e-59 199.3 0.0 1.1e-58 198.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX82248.1 - 6.3e-29 101.0 0.0 9.7e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX82248.1 - 0.00044 19.7 0.2 0.00085 18.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORX82248.1 - 0.0074 15.9 0.2 0.2 11.3 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 ORX82248.1 - 0.019 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 ORX82248.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORX82248.1 - 0.021 14.4 4.0 0.046 13.3 0.0 2.6 2 1 0 3 3 3 0 RIO1 family Kdo PF06293.14 ORX82248.1 - 0.037 13.4 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX82248.1 - 0.13 11.2 0.1 0.13 11.2 0.1 2.4 1 1 1 2 2 2 0 Haspin like kinase domain EMP24_GP25L PF01105.24 ORX82306.1 - 4.8e-43 147.2 1.7 5.7e-43 147.0 1.7 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 ORX82306.1 - 0.21 11.8 1.0 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 ATP-synt_8 PF00895.20 ORX82306.1 - 0.25 11.8 1.8 1.5 9.4 0.5 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 HPP PF04982.13 ORX82307.1 - 1.1e-43 148.3 8.6 1.1e-43 148.3 8.6 1.7 2 0 0 2 2 2 1 HPP family RE_ScaI PF09569.10 ORX82307.1 - 0.042 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease DUF3792 PF12670.7 ORX82307.1 - 0.89 9.7 11.4 0.091 12.9 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) HLH PF00010.26 ORX82308.1 - 2.5e-14 52.9 0.8 5.5e-14 51.9 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 ORX82309.1 - 1.1e-46 155.8 23.0 1.7e-08 35.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX82309.1 - 1.8e-16 60.2 7.5 0.033 14.5 0.0 7.0 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX82309.1 - 5e-07 29.8 1.1 0.00035 20.5 0.1 3.4 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORX82309.1 - 0.0033 15.5 4.1 0.012 13.7 1.4 2.6 2 1 1 3 3 3 2 IKI3 family Nucleoporin_N PF08801.11 ORX82309.1 - 0.012 14.4 0.3 1.2 7.8 0.0 2.8 1 1 1 2 2 2 0 Nup133 N terminal like Coatomer_WDAD PF04053.14 ORX82309.1 - 0.039 13.0 0.5 0.52 9.3 0.2 2.8 3 1 0 3 3 3 0 Coatomer WD associated region SDF PF00375.18 ORX82310.1 - 6e-101 338.3 38.1 6.8e-101 338.1 38.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF92 PF01940.16 ORX82311.1 - 1.5 8.2 5.7 3.8 6.8 1.8 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF92 UDG PF03167.19 ORX82312.1 - 4e-20 72.4 0.0 5.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily WD40 PF00400.32 ORX82313.1 - 4.9e-18 65.2 6.3 3.8e-06 27.5 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX82313.1 - 6.2e-12 45.6 0.1 0.021 15.1 0.0 5.0 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORX82313.1 - 6.4e-05 21.7 0.1 0.0024 16.5 0.1 2.2 1 1 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 ORX82313.1 - 9.2e-05 21.9 0.1 0.011 15.1 0.1 2.2 2 0 0 2 2 2 2 WD40-like domain THP2 PF09432.10 ORX82313.1 - 0.021 14.9 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Tho complex subunit THP2 Rer1 PF03248.13 ORX82314.1 - 8.6e-79 263.2 5.4 1e-78 263.0 5.4 1.0 1 0 0 1 1 1 1 Rer1 family Ferlin_C PF16165.5 ORX82314.1 - 3 7.8 5.6 11 6.0 0.1 2.2 2 0 0 2 2 2 0 Ferlin C-terminus DUF2208 PF09973.9 ORX82314.1 - 3.5 7.2 10.4 0.16 11.6 3.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Ribosomal_L28e PF01778.17 ORX82315.1 - 4.7e-34 117.6 0.5 6.5e-34 117.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_transf_20 PF00982.21 ORX82316.1 - 9.8e-170 565.3 0.0 1.3e-169 564.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORX82316.1 - 9e-63 211.5 0.0 1.4e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORX82316.1 - 1e-10 41.8 0.0 0.0001 22.1 0.0 2.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORX82316.1 - 0.0045 16.6 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Glyco_transf_5 PF08323.11 ORX82316.1 - 0.047 13.4 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF1724 PF08350.10 ORX82316.1 - 0.39 10.9 4.0 5.4 7.2 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1724) BAG PF02179.16 ORX82317.1 - 2.6e-09 37.4 0.2 2.6e-09 37.4 0.2 2.2 2 0 0 2 2 2 1 BAG domain LRR_6 PF13516.6 ORX82350.1 - 0.069 13.2 9.3 0.93 9.7 0.2 5.2 6 0 0 6 6 6 0 Leucine Rich repeat LRR_2 PF07723.13 ORX82350.1 - 6.6 7.6 10.3 7.6 7.4 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 ORX82350.1 - 8.4 6.2 14.0 2.7 7.8 0.1 5.7 6 2 0 6 6 6 0 Leucine rich repeat Ribosomal_S17_N PF16205.5 ORX82351.1 - 2.2e-33 114.4 0.2 4.7e-33 113.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORX82351.1 - 2.7e-27 94.7 0.4 4.1e-27 94.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF974 PF06159.13 ORX82353.1 - 1.4e-65 221.5 0.0 1.8e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 ORX82353.1 - 0.0036 17.4 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.7 ORX82353.1 - 0.0073 15.7 0.0 0.07 12.5 0.0 2.5 2 1 2 4 4 4 1 TRAPP trafficking subunit Trs65 Acylphosphatase PF00708.18 ORX82353.1 - 0.21 12.0 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase Hydrolase_6 PF13344.6 ORX82355.1 - 5.1e-28 97.2 0.0 9.6e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX82355.1 - 2e-22 79.0 0.0 3.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORX82355.1 - 3.3e-09 37.4 0.0 4.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX82355.1 - 1.8e-07 31.5 0.0 0.00076 19.6 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase TFIID-18kDa PF02269.16 ORX82356.1 - 3.9e-30 103.7 0.3 4.9e-30 103.4 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CUE PF02845.16 ORX82357.1 - 1.1e-09 37.8 0.2 2.7e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 CUE domain INCENP_N PF12178.8 ORX82357.1 - 0.027 14.5 1.7 0.032 14.2 0.1 2.0 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal polyprenyl_synt PF00348.17 ORX82358.1 - 1.2e-73 247.4 0.0 2e-73 246.6 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 ORX82358.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Flavi_NS5 PF00972.20 ORX82358.1 - 0.17 10.0 0.0 0.26 9.4 0.0 1.2 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Ribosomal_L23eN PF03939.13 ORX82359.1 - 3.6e-24 84.7 7.7 6.5e-24 83.9 7.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORX82359.1 - 4.4e-14 52.6 1.6 1.3e-13 51.0 0.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 CPT_N PF16484.5 ORX82360.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus CoA_trans PF01144.23 ORX82361.1 - 1.1e-112 374.7 1.5 2.4e-70 236.3 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ORX82361.1 - 0.0079 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SKG6 PF08693.10 ORX82397.1 - 2.4 7.6 5.8 0.19 11.2 0.5 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ion_trans PF00520.31 ORX82398.1 - 0.0023 17.2 14.2 0.0031 16.8 14.2 1.1 1 0 0 1 1 1 1 Ion transport protein TssN PF17555.2 ORX82398.1 - 0.048 13.0 6.7 0.059 12.7 6.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Ndc1_Nup PF09531.10 ORX82398.1 - 1.9 7.1 6.7 2.3 6.8 6.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CitMHS PF03600.16 ORX82398.1 - 3.3 6.8 7.8 6.2 5.9 7.8 1.3 1 1 0 1 1 1 0 Citrate transporter DUF2670 PF10875.8 ORX82399.1 - 0.55 10.3 4.6 0.82 9.8 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) FMN_red PF03358.15 ORX82400.1 - 1.5e-34 119.0 0.0 1.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX82400.1 - 2.7e-07 30.5 0.0 3.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Myb_DNA-bind_4 PF13837.6 ORX82401.1 - 2.1e-18 66.5 4.9 2.1e-18 66.5 4.9 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX82401.1 - 6.6e-09 35.8 0.8 1.9e-08 34.3 0.8 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX82401.1 - 1.1e-08 35.2 3.9 1.1e-08 35.2 3.9 2.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX82401.1 - 0.001 19.3 2.2 0.001 19.3 2.2 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORX82401.1 - 0.0036 18.3 2.7 0.0036 18.3 2.7 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DYW_deaminase PF14432.6 ORX82401.1 - 0.063 13.1 1.1 0.22 11.4 0.4 2.0 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases SopE_GEF PF07487.13 ORX82401.1 - 0.069 13.2 1.2 0.29 11.2 0.2 2.2 2 0 0 2 2 2 0 SopE GEF domain DUF3915 PF13054.6 ORX82401.1 - 2.3 8.2 5.1 4.7 7.2 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) UDPGP PF01704.18 ORX82402.1 - 5.1e-58 196.7 0.0 6.8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORX82402.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain URO-D PF01208.17 ORX82403.1 - 1.4e-130 435.5 0.0 1.6e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.11 ORX82403.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain FIST PF08495.10 ORX82404.1 - 2.2e-14 53.8 0.0 3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 FIST N domain FA_hydroxylase PF04116.13 ORX82405.1 - 2.3e-24 86.3 21.4 2.3e-24 86.3 21.4 2.1 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Arf PF00025.21 ORX82406.1 - 2.4e-77 258.3 0.0 2.8e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX82406.1 - 1.4e-15 57.6 0.1 1.8e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX82406.1 - 1.3e-13 50.9 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORX82406.1 - 1.4e-13 50.6 0.0 1.7e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORX82406.1 - 7e-12 45.2 0.7 1.7e-07 30.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORX82406.1 - 8.4e-10 38.4 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX82406.1 - 0.0002 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX82406.1 - 0.0043 16.4 0.1 0.0058 16.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NDK PF00334.19 ORX82407.1 - 1.2e-42 145.2 0.0 1.5e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase AMP-binding PF00501.28 ORX82408.1 - 2.5e-91 306.4 0.0 3.1e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX82408.1 - 3.6e-25 88.8 0.2 7.9e-25 87.6 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORX82408.1 - 1e-21 76.6 0.4 2.3e-21 75.5 0.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus LRR_8 PF13855.6 ORX82445.1 - 4.2e-21 74.5 25.2 1.3e-09 37.7 3.3 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORX82445.1 - 2e-11 43.9 5.4 2.7e-05 24.4 0.3 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX82445.1 - 1.3e-05 25.0 8.9 0.89 10.3 0.0 4.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 ORX82445.1 - 0.00088 19.1 5.3 0.62 10.3 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 ORX82445.1 - 0.014 14.9 1.2 0.016 14.7 1.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeat LRR_3 PF07725.12 ORX82445.1 - 0.053 13.4 0.2 0.053 13.4 0.2 3.1 4 0 0 4 4 4 0 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 ORX82445.1 - 0.073 13.1 0.1 5.3 7.2 0.0 2.9 1 1 2 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain CENP-Q PF13094.6 ORX82446.1 - 0.0098 16.1 1.0 0.012 15.8 1.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_S28e PF01200.18 ORX82447.1 - 1.4e-33 114.7 1.2 1.6e-33 114.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORX82447.1 - 0.042 14.2 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORX82447.1 - 0.058 13.4 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region PP2C PF00481.21 ORX82448.1 - 2.3e-40 138.9 0.0 2.3e-38 132.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Nitrate_red_del PF02613.15 ORX82448.1 - 0.049 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase delta subunit PP2C_2 PF13672.6 ORX82448.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C C2 PF00168.30 ORX82449.1 - 9.4e-110 359.9 3.3 2.5e-22 79.1 0.0 6.5 6 0 0 6 6 6 6 C2 domain Cep57_MT_bd PF06657.13 ORX82450.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Hc1 PF07432.13 ORX82450.1 - 0.75 10.2 8.4 1.3 9.5 8.4 1.4 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Argos PF11581.8 ORX82451.1 - 0.099 12.7 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos PmrD PF11183.8 ORX82451.1 - 0.12 12.6 0.4 0.22 11.6 0.4 1.4 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Peptidase_S8 PF00082.22 ORX82452.1 - 4.9e-33 114.7 21.1 9.7e-33 113.7 21.1 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX82452.1 - 0.00052 20.6 0.4 0.0056 17.3 0.1 2.4 1 1 1 2 2 2 1 Peptidase inhibitor I9 GATA PF00320.27 ORX82486.1 - 1.4e-28 98.2 16.1 5.2e-15 54.8 4.4 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORX82486.1 - 5.8e-11 42.0 1.6 1.7e-10 40.5 1.6 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 ORX82486.1 - 0.00043 20.3 0.8 0.22 11.7 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORX82486.1 - 0.0027 17.2 6.2 0.027 14.0 0.3 2.7 2 1 0 2 2 2 1 TFIIB zinc-binding Vps36-NZF-N PF16988.5 ORX82486.1 - 0.019 14.4 8.6 1.1 8.7 1.1 4.1 1 1 3 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OTT_1508_deam PF14441.6 ORX82486.1 - 0.028 14.4 0.5 12 6.0 0.1 2.8 2 0 0 2 2 2 0 OTT_1508-like deaminase Zn_Tnp_IS1595 PF12760.7 ORX82486.1 - 0.031 14.2 3.6 3.6 7.6 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.17 ORX82486.1 - 0.24 11.3 5.5 3.3 7.6 0.7 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2318 PF10080.9 ORX82486.1 - 0.56 10.4 3.4 44 4.3 1.0 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) DZR PF12773.7 ORX82486.1 - 0.74 9.9 10.8 2.7 8.1 7.8 3.2 2 1 2 4 4 4 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORX82486.1 - 1.1 9.2 7.0 1.3 9.0 1.4 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_15 PF17032.5 ORX82486.1 - 1.4 9.7 6.8 11 6.8 6.9 2.5 1 1 2 3 3 3 0 zinc-ribbon family ZF-HD_dimer PF04770.12 ORX82486.1 - 2.5 8.5 7.8 7.8 6.9 0.1 3.3 2 1 1 3 3 3 0 ZF-HD protein dimerisation region Auto_anti-p27 PF06677.12 ORX82486.1 - 2.9 8.1 6.0 1.7 8.8 0.6 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-B_box PF00643.24 ORX82486.1 - 3 8.1 9.0 31 4.8 0.0 3.9 4 0 0 4 4 4 0 B-box zinc finger A2L_zn_ribbon PF08792.10 ORX82486.1 - 6.3 6.6 7.5 11 5.8 0.0 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain PAPS_reduct PF01507.19 ORX82487.1 - 1.3e-28 100.2 0.0 3.6e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pyridoxal_deC PF00282.19 ORX82488.1 - 1.6e-87 293.7 0.0 2e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ORX82488.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORX82488.1 - 8.7e-05 21.6 0.0 0.00084 18.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V SepSecS PF05889.13 ORX82488.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Acyl-CoA_dh_1 PF00441.24 ORX82490.1 - 4.3e-43 147.1 0.7 6.4e-43 146.5 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORX82490.1 - 2.2e-26 92.7 0.1 8.2e-26 90.9 0.0 2.0 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORX82490.1 - 4.1e-22 78.2 0.0 7.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORX82490.1 - 9e-18 64.8 0.0 2.2e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 ORX82490.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein Ecl1 PF12855.7 ORX82491.1 - 7.5e-09 37.0 0.0 7.6e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins SRCR_2 PF15494.6 ORX82491.1 - 0.025 15.1 0.1 0.028 14.9 0.1 1.1 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain zf-C2H2_jaz PF12171.8 ORX82491.1 - 0.97 9.8 0.1 0.97 9.8 0.1 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MRP-L27 PF09809.9 ORX82492.1 - 3.1e-19 68.9 0.0 3.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 p450 PF00067.22 ORX82529.1 - 8.1e-90 301.8 0.0 1.5e-89 300.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORX82529.1 - 1.3e-31 109.9 0.0 2.3e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX82529.1 - 6.2e-23 81.6 0.0 1.3e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORX82529.1 - 5.4e-15 56.0 0.0 6.3e-14 52.5 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DUF3072 PF11272.8 ORX82529.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) PH PF00169.29 ORX82530.1 - 5.2e-10 39.8 0.1 8.6e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 PH domain PBD PF00786.28 ORX82530.1 - 9.6e-08 32.3 0.1 2.6e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 P21-Rho-binding domain RhoGAP PF00620.27 ORX82531.1 - 0.016 15.0 0.1 0.058 13.2 0.0 1.9 2 1 0 2 2 2 0 RhoGAP domain zf-H2C2_2 PF13465.6 ORX82532.1 - 7.2e-22 76.8 21.7 2.3e-09 37.2 0.4 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX82532.1 - 1.1e-17 63.4 26.2 1.7e-05 25.0 0.9 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX82532.1 - 3.2e-10 40.0 24.2 0.0055 17.4 0.8 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX82532.1 - 3e-06 27.8 4.5 0.2 12.3 0.1 3.5 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX82532.1 - 3.7e-05 24.0 9.7 0.02 15.2 0.9 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORX82532.1 - 0.00048 20.3 11.9 0.12 12.7 0.1 4.2 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX82532.1 - 0.043 14.5 11.4 1.3 9.8 2.7 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger zf-met PF12874.7 ORX82532.1 - 0.044 14.2 10.2 10 6.7 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX82532.1 - 0.052 13.5 1.9 5.2 7.1 0.0 3.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORX82532.1 - 0.43 10.6 13.7 3.7 7.6 0.8 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger PAS_9 PF13426.7 ORX82533.1 - 4.1e-27 94.5 0.0 4.8e-14 52.5 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ORX82533.1 - 3.2e-22 78.6 0.0 7.8e-12 45.3 0.0 3.8 4 1 0 4 4 4 3 PAS fold PAS PF00989.25 ORX82533.1 - 3.5e-19 68.9 0.0 2.6e-08 33.8 0.0 3.9 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 ORX82533.1 - 1.4e-12 47.0 4.3 2.9e-12 46.0 4.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 ORX82533.1 - 7.9e-10 38.9 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORX82533.1 - 3e-08 33.9 0.0 0.0065 16.7 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 ORX82533.1 - 0.00058 20.5 0.0 0.58 10.8 0.0 3.5 4 0 0 4 4 4 1 PAS fold zf-C2H2 PF00096.26 ORX82534.1 - 1.4e-20 72.5 28.5 8.5e-06 25.9 1.1 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX82534.1 - 1.2e-19 69.7 17.7 2.9e-07 30.6 0.1 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX82534.1 - 3.5e-12 46.1 26.1 0.003 18.3 0.6 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX82534.1 - 7.3e-07 29.7 7.4 0.21 12.3 1.6 3.3 2 2 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX82534.1 - 1.6e-05 25.0 11.2 0.014 15.6 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX82534.1 - 1.9e-05 24.9 6.2 0.022 15.1 0.5 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX82534.1 - 0.0025 18.5 1.0 0.0025 18.5 1.0 3.0 3 0 0 3 3 3 1 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORX82534.1 - 0.098 12.8 7.7 0.13 12.4 0.2 3.2 1 1 3 4 4 4 0 Aberrant zinc-finger HTH_18 PF12833.7 ORX82534.1 - 0.11 12.8 1.5 12 6.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain zf-LYAR PF08790.11 ORX82534.1 - 0.25 11.3 4.5 28 4.7 0.1 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-met PF12874.7 ORX82534.1 - 0.3 11.5 10.9 14 6.2 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type RPAP2_Rtr1 PF04181.13 ORX82534.1 - 0.61 10.5 4.3 9.3 6.7 0.3 2.4 2 1 0 2 2 2 0 Rtr1/RPAP2 family zf-C2H2_6 PF13912.6 ORX82534.1 - 0.74 9.9 14.7 2.4 8.3 0.5 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX82535.1 - 1.4e-20 72.5 28.0 3.4e-06 27.2 0.2 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX82535.1 - 9.2e-18 63.8 23.9 1.6e-08 34.6 0.1 4.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX82535.1 - 2.9e-13 49.4 26.5 0.0014 19.3 0.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX82535.1 - 6e-05 23.2 8.3 0.14 12.4 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX82535.1 - 0.00057 20.5 10.2 0.11 13.1 0.5 3.5 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX82535.1 - 0.0064 16.8 7.0 0.19 12.1 0.8 2.5 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX82535.1 - 0.0089 16.7 1.9 0.0089 16.7 1.9 2.8 1 1 2 3 3 3 1 TRAF-type zinc finger zf-MYST PF17772.1 ORX82535.1 - 0.029 14.0 1.8 7.3 6.3 0.5 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 ORX82535.1 - 0.035 13.9 15.2 0.67 9.8 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORX82535.1 - 0.1 12.6 19.6 0.15 12.1 0.9 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger ADK_lid PF05191.14 ORX82535.1 - 0.11 12.5 4.7 2.2 8.3 0.1 3.3 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-met PF12874.7 ORX82535.1 - 0.31 11.5 9.0 5.2 7.6 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORX82535.1 - 3.7 7.8 7.9 0.44 10.7 1.6 2.6 2 1 1 3 3 3 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 ORX82536.1 - 1.5e-19 69.5 18.6 1.7e-08 34.5 0.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX82536.1 - 1.5e-18 66.1 29.7 3.7e-06 27.1 0.2 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX82536.1 - 6.6e-13 48.3 26.1 0.0015 19.2 0.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX82536.1 - 8e-05 22.8 9.7 0.16 12.3 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX82536.1 - 0.0009 19.9 6.7 0.0049 17.5 1.9 2.3 1 1 1 2 2 2 1 TRAF-type zinc finger FOXP-CC PF16159.5 ORX82536.1 - 0.0043 17.6 8.3 0.067 13.8 0.4 3.0 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 ORX82536.1 - 0.026 14.3 16.6 0.72 9.7 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain ADK_lid PF05191.14 ORX82536.1 - 0.06 13.3 4.8 2.7 8.0 0.1 3.3 3 1 0 3 3 3 0 Adenylate kinase, active site lid CHORD PF04968.12 ORX82536.1 - 0.067 13.9 4.8 2.3 9.0 0.1 2.9 3 1 0 3 3 3 0 CHORD zf-C2H2_6 PF13912.6 ORX82536.1 - 0.11 12.5 20.3 0.15 12.1 0.8 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger zf-MYST PF17772.1 ORX82536.1 - 0.13 11.9 1.2 16 5.2 0.0 3.1 2 1 1 3 3 3 0 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 ORX82536.1 - 0.29 11.3 4.1 0.27 11.4 1.0 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.7 ORX82536.1 - 1.9 9.0 12.9 5.6 7.5 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORX82537.1 - 1.3e-20 72.6 27.5 5.9e-06 26.5 0.6 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX82537.1 - 5.7e-19 67.6 17.5 1.8e-07 31.2 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX82537.1 - 1.7e-11 43.9 25.8 0.0019 18.9 0.6 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX82537.1 - 2.7e-07 30.7 6.8 0.0092 16.2 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX82537.1 - 9.8e-06 26.1 6.8 0.17 12.6 1.5 3.3 2 2 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX82537.1 - 0.00024 21.4 5.7 0.051 13.9 0.4 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX82537.1 - 0.0014 19.3 1.1 0.0014 19.3 1.1 3.0 2 1 1 3 3 3 1 TRAF-type zinc finger zf-met PF12874.7 ORX82537.1 - 0.044 14.2 9.7 9.2 6.8 0.2 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type HTH_18 PF12833.7 ORX82537.1 - 0.077 13.3 1.4 7.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain zf-C2H2_6 PF13912.6 ORX82537.1 - 0.19 11.7 15.3 1.6 8.8 0.5 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger RPAP2_Rtr1 PF04181.13 ORX82537.1 - 0.56 10.6 3.8 11 6.4 0.2 2.3 2 0 0 2 2 2 0 Rtr1/RPAP2 family zf-C2H2_aberr PF17017.5 ORX82537.1 - 1.2 9.2 8.0 2.1 8.4 0.3 3.2 1 1 2 4 4 4 0 Aberrant zinc-finger zf-LYAR PF08790.11 ORX82537.1 - 1.4 8.9 7.4 25 4.9 0.3 3.8 4 1 0 4 4 4 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 ORX82537.1 - 9.7 6.4 8.2 13 6.0 1.0 2.9 2 1 1 3 3 3 0 Zinc ribbon domain F-box-like PF12937.7 ORX82538.1 - 5.1e-05 23.1 0.2 5.1e-05 23.1 0.2 2.6 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 ORX82538.1 - 0.24 11.9 9.3 6.9 7.2 0.3 5.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Acetyltransf_1 PF00583.25 ORX82573.1 - 0.00068 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX82573.1 - 0.017 15.5 0.1 0.026 14.9 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX82573.1 - 0.083 12.8 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AstA PF04958.12 ORX82573.1 - 0.091 11.3 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF5383 PF17355.2 ORX82574.1 - 0.054 13.9 0.3 0.07 13.5 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) HR1 PF02185.16 ORX82575.1 - 0.0034 17.5 2.1 0.0066 16.5 2.1 1.5 1 0 0 1 1 1 1 Hr1 repeat BLOC1_2 PF10046.9 ORX82575.1 - 0.074 13.4 3.5 0.27 11.6 0.1 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CHDCT2 PF08074.11 ORX82575.1 - 0.56 10.4 3.5 0.3 11.2 1.0 1.7 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain PI3K_P85_iSH2 PF16454.5 ORX82575.1 - 2.6 7.6 7.2 10 5.7 7.2 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PAS_9 PF13426.7 ORX82576.1 - 3.4e-28 98.0 0.0 1.5e-14 54.1 0.0 3.5 3 1 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ORX82576.1 - 7.7e-22 77.4 0.0 9e-13 48.3 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 ORX82576.1 - 1.6e-17 63.5 0.0 4.5e-10 39.5 0.0 3.6 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.10 ORX82576.1 - 3.1e-15 56.4 0.0 0.00029 21.0 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORX82576.1 - 5.6e-12 45.8 0.0 2.8e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 ORX82576.1 - 5.2e-05 23.2 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 ORX82576.1 - 0.0014 19.2 0.0 27 5.5 0.0 3.3 3 0 0 3 3 3 0 PAS fold Polysacc_deac_1 PF01522.21 ORX82577.1 - 2.5e-13 50.0 0.0 1.9e-12 47.2 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide deacetylase TPR_2 PF07719.17 ORX82578.1 - 2.9e-35 117.5 1.3 5.9e-06 26.0 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORX82578.1 - 1.8e-34 116.1 0.4 3.5e-07 29.8 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORX82578.1 - 2e-24 83.7 0.3 0.0035 17.5 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORX82578.1 - 6e-20 70.7 5.5 1.4e-06 27.9 0.0 7.1 5 2 3 8 8 8 3 TPR repeat TPR_12 PF13424.6 ORX82578.1 - 1.6e-19 70.0 0.5 0.0029 17.9 0.2 5.7 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORX82578.1 - 3.6e-19 69.1 0.0 7.3e-05 23.3 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX82578.1 - 4.2e-17 61.4 0.0 0.11 13.3 0.0 6.6 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORX82578.1 - 1.8e-16 60.4 0.0 4.4e-05 23.9 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX82578.1 - 7e-15 55.0 3.1 0.0017 18.5 0.1 4.7 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORX82578.1 - 2.1e-13 49.6 0.1 0.0034 17.6 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX82578.1 - 2.7e-13 48.9 0.7 0.051 13.6 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORX82578.1 - 2.3e-09 37.2 0.0 0.0028 17.8 0.2 4.1 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 ORX82578.1 - 7.9e-08 32.5 3.7 3.6 8.4 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORX82578.1 - 1.9e-07 30.6 0.0 0.011 15.0 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX82578.1 - 0.00079 19.2 0.1 1.2e+02 2.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX82578.1 - 0.0008 18.9 0.0 0.34 10.2 0.0 3.1 2 1 1 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 ORX82578.1 - 0.0096 15.7 0.0 0.073 12.8 0.0 2.5 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 ORX82578.1 - 0.0098 16.3 0.3 14 6.1 0.0 3.5 3 2 1 4 4 3 0 Bacterial transcriptional activator domain Sel1 PF08238.12 ORX82578.1 - 0.014 16.0 0.2 29 5.5 0.0 3.6 3 0 0 3 3 3 0 Sel1 repeat APP_E2 PF12925.7 ORX82578.1 - 0.018 14.7 0.7 1 9.1 0.1 2.9 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein MIT PF04212.18 ORX82578.1 - 0.09 12.9 6.8 17 5.5 0.0 4.8 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.7 ORX82578.1 - 0.12 12.6 0.0 0.67 10.2 0.0 2.2 2 1 0 2 2 2 0 Tetratrico peptide repeat Arrestin_N PF00339.29 ORX82579.1 - 3.5e-09 36.9 1.2 3.7e-08 33.5 0.1 2.7 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX82579.1 - 1.3e-07 32.1 1.9 4.2e-05 24.0 0.4 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX82579.1 - 0.042 13.5 0.1 0.27 10.9 0.0 2.0 1 1 0 2 2 2 0 Arrestin_N terminal like Peptidase_M90 PF06167.12 ORX82579.1 - 0.11 12.1 0.3 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 FHA PF00498.26 ORX82619.1 - 9.8e-18 64.3 0.0 2e-17 63.3 0.0 1.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 ORX82619.1 - 0.00011 22.5 0.0 0.00036 20.8 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain AAA PF00004.29 ORX82620.1 - 6.7e-97 321.0 0.0 4.9e-47 159.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX82620.1 - 2.3e-26 91.3 6.3 1.2e-12 47.4 0.4 3.2 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 ORX82620.1 - 1.5e-19 70.0 0.3 7.8e-19 67.6 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ORX82620.1 - 3e-14 53.1 0.0 7.7e-06 25.7 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX82620.1 - 1.9e-13 50.9 0.0 1.7e-07 31.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 ORX82620.1 - 2.4e-12 46.4 0.0 5.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 ORX82620.1 - 1e-11 45.2 0.0 5.5e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORX82620.1 - 3.4e-11 43.8 0.1 0.00045 20.6 0.0 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 ORX82620.1 - 5.8e-11 42.6 0.2 3.7e-05 23.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX82620.1 - 1.1e-08 35.5 0.1 0.061 13.6 0.0 3.9 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORX82620.1 - 1.3e-08 34.4 0.1 0.0018 17.5 0.0 2.9 2 1 1 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 ORX82620.1 - 8.3e-08 32.6 0.0 0.0051 17.2 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 ORX82620.1 - 2.1e-07 30.6 0.2 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 ORX82620.1 - 3.6e-07 30.1 0.2 6e-06 26.2 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 ORX82620.1 - 4e-07 30.1 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORX82620.1 - 4.5e-07 30.5 0.1 0.031 14.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 ORX82620.1 - 5.1e-07 30.3 0.0 0.0068 16.9 0.0 4.1 3 1 0 3 3 3 1 ABC transporter IstB_IS21 PF01695.17 ORX82620.1 - 2e-06 27.7 0.0 0.062 13.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 ORX82620.1 - 8.9e-06 25.0 0.1 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 ORX82620.1 - 1.1e-05 25.0 0.0 0.064 12.8 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 ORX82620.1 - 1.2e-05 24.8 0.2 0.51 9.6 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 ORX82620.1 - 1.4e-05 25.4 0.0 0.16 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 ORX82620.1 - 1.8e-05 24.7 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_25 PF13481.6 ORX82620.1 - 2.9e-05 23.8 2.4 1.6 8.2 0.0 3.7 2 2 2 4 4 3 2 AAA domain ATPase_2 PF01637.18 ORX82620.1 - 3.9e-05 23.7 0.4 0.26 11.2 0.0 3.4 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORX82620.1 - 4.4e-05 23.3 0.0 0.12 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 ORX82620.1 - 7.9e-05 21.9 0.0 0.039 13.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 ORX82620.1 - 8.8e-05 22.3 0.0 0.0066 16.2 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 ORX82620.1 - 9.5e-05 22.2 0.0 0.63 9.7 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 ORX82620.1 - 0.00014 21.9 0.0 0.31 11.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 ORX82620.1 - 0.00015 22.2 2.2 0.55 10.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_3 PF07726.11 ORX82620.1 - 0.00046 20.1 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX82620.1 - 0.00071 19.5 0.2 0.3 11.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 ORX82620.1 - 0.00074 18.9 0.0 0.52 9.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.16 ORX82620.1 - 0.00074 19.0 0.2 1.2 8.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 ORX82620.1 - 0.0008 19.4 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 ORX82620.1 - 0.001 18.3 0.0 0.18 11.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.6 ORX82620.1 - 0.0021 17.9 0.6 1.4 8.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.9 ORX82620.1 - 0.0029 16.9 0.1 1.4 8.1 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 ORX82620.1 - 0.0092 15.9 0.0 0.88 9.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 ORX82620.1 - 0.0097 16.0 0.0 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 ORX82620.1 - 0.011 16.1 0.9 13 6.1 0.0 3.5 3 1 1 4 4 3 0 AAA domain NTPase_1 PF03266.15 ORX82620.1 - 0.018 14.9 0.6 5 7.0 0.0 3.8 4 0 0 4 4 4 0 NTPase AAA_30 PF13604.6 ORX82620.1 - 0.02 14.6 0.1 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 ORX82620.1 - 0.033 14.3 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase-like family Molydop_binding PF01568.21 ORX82620.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Zot PF05707.12 ORX82620.1 - 0.16 11.6 0.0 2.3 7.8 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 ORX82620.1 - 0.2 11.4 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 ORX82620.1 - 0.2 11.0 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase RRM_1 PF00076.22 ORX82621.1 - 3.6e-13 49.1 0.0 8.9e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_S1 PF05827.12 ORX82622.1 - 3.2e-08 33.5 0.0 5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pyr_redox_3 PF13738.6 ORX82622.1 - 0.07 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase V-ATPase_C PF03223.15 ORX82623.1 - 9.5e-135 449.7 5.9 1.1e-134 449.6 5.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Glyco_hydro_46 PF01374.18 ORX82625.1 - 2.3e-43 148.3 0.0 2.9e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 FUSC_2 PF13515.6 ORX82626.1 - 2.2e-16 60.1 15.8 2.2e-16 60.1 15.8 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 ORX82626.1 - 5.8e-11 41.9 19.9 6e-11 41.9 18.3 1.8 1 1 0 1 1 1 1 Aluminium activated malate transporter ArAE_2 PF10334.9 ORX82626.1 - 5e-09 36.3 0.2 2.5e-08 34.0 0.1 2.2 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ORX82626.1 - 2.5e-05 23.1 15.1 5.2e-05 22.0 15.1 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF2891 PF11199.8 ORX82626.1 - 0.059 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) partial_CstF PF15861.5 ORX82626.1 - 0.14 11.9 1.2 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain MOZ_SAS PF01853.18 ORX82627.1 - 8.7e-83 276.4 0.5 1.5e-82 275.6 0.5 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 ORX82627.1 - 6.1e-22 77.3 0.2 1.7e-21 75.8 0.1 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 ORX82627.1 - 1.2e-21 76.1 4.0 3.5e-21 74.6 4.0 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ORX82627.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX82627.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PAP_assoc PF03828.19 ORX82661.1 - 1e-18 67.3 0.2 3.4e-18 65.6 0.1 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORX82661.1 - 6.2e-07 29.6 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORX82661.1 - 0.0031 17.6 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RRM_1 PF00076.22 ORX82662.1 - 9.3e-71 233.6 4.3 6.5e-20 70.7 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX82662.1 - 2.2e-24 85.1 0.0 1.2e-08 34.7 0.0 4.5 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_5 PF13893.6 ORX82662.1 - 8e-12 44.9 0.0 0.045 13.4 0.0 4.5 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX82662.1 - 3.2e-11 43.0 1.2 0.00093 19.2 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif NRDE-2 PF08424.10 ORX82662.1 - 7.2e-08 31.9 15.0 0.04 13.1 0.5 5.3 1 1 2 3 3 3 3 NRDE-2, necessary for RNA interference DUF1866 PF08952.11 ORX82662.1 - 0.00026 20.9 0.0 1 9.2 0.0 3.9 2 1 2 4 4 4 1 Domain of unknown function (DUF1866) RRM_7 PF16367.5 ORX82662.1 - 0.00036 20.6 0.3 52 4.0 0.0 5.9 6 0 0 6 6 6 0 RNA recognition motif RRM_Rrp7 PF17799.1 ORX82662.1 - 0.00038 20.3 1.6 0.026 14.3 0.0 3.9 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain U3_assoc_6 PF08640.11 ORX82662.1 - 0.3 11.2 15.5 0.49 10.5 0.1 4.3 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 GAGA_bind PF06217.12 ORX82662.1 - 0.54 10.5 8.2 1.7 8.9 8.2 1.8 1 0 0 1 1 1 0 GAGA binding protein-like family SF3A3 PF16837.5 ORX82662.1 - 7.1 7.2 6.5 45 4.7 0.0 3.9 4 0 0 4 4 4 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DnaJ_C PF01556.18 ORX82664.1 - 2.1e-39 135.0 0.0 2.7e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORX82664.1 - 7e-26 90.1 3.2 1.2e-25 89.4 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 ORX82664.1 - 0.051 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein LEA_2 PF03168.13 ORX82665.1 - 6.6e-06 26.6 0.0 8.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein Cation_efflux PF01545.21 ORX82666.1 - 2.8e-27 95.8 5.6 4e-27 95.2 5.6 1.2 1 0 0 1 1 1 1 Cation efflux family ATP1G1_PLM_MAT8 PF02038.16 ORX82666.1 - 0.51 9.8 0.0 0.51 9.8 0.0 4.0 5 0 0 5 5 5 0 ATP1G1/PLM/MAT8 family BAR_2 PF10455.9 ORX82667.1 - 1.5e-47 162.2 0.7 3.2e-46 157.8 0.7 2.0 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORX82667.1 - 2.7e-26 92.7 1.0 7.5e-26 91.2 1.0 1.6 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORX82667.1 - 9e-09 35.4 0.3 2.3e-08 34.1 0.1 1.6 2 0 0 2 2 2 1 BAR domain of APPL family Arfaptin PF06456.13 ORX82667.1 - 0.0098 15.5 2.0 2.6 7.6 0.6 2.4 2 1 0 2 2 2 2 Arfaptin-like domain IMD PF08397.11 ORX82667.1 - 0.052 12.9 0.6 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 IRSp53/MIM homology domain T3SS_basalb_I PF17001.5 ORX82667.1 - 0.086 13.4 0.8 8.3 7.1 0.1 2.7 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Med21 PF11221.8 ORX82667.1 - 0.19 12.0 7.3 0.23 11.7 3.1 2.8 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Vps5 PF09325.10 ORX82667.1 - 0.52 9.8 4.1 1.8 8.0 0.4 2.5 2 0 0 2 2 2 0 Vps5 C terminal like LPP PF04728.13 ORX82667.1 - 0.84 10.1 6.0 1.3 9.5 0.4 3.4 4 1 0 4 4 4 0 Lipoprotein leucine-zipper MotA_ExbB PF01618.16 ORX82668.1 - 0.24 11.2 0.1 0.26 11.0 0.1 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family FTR1 PF03239.14 ORX82669.1 - 9.1e-71 238.5 6.9 1.1e-70 238.2 6.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Peptidase_U4 PF03419.13 ORX82669.1 - 0.0051 16.1 3.2 0.0051 16.1 3.2 2.1 2 0 0 2 2 2 1 Sporulation factor SpoIIGA OpgC_C PF10129.9 ORX82669.1 - 0.018 14.0 4.4 0.035 13.0 4.4 1.5 1 0 0 1 1 1 0 OpgC protein Phage_holin_3_6 PF07332.11 ORX82669.1 - 3.3 7.8 15.9 0.17 11.9 0.8 3.4 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 ORX82670.1 - 5.7e-51 173.4 0.1 9.2e-51 172.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX82670.1 - 1.1e-23 83.8 0.0 5e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ORX82670.1 - 0.00068 18.7 0.3 0.001 18.1 0.3 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Inhibitor_I9 PF05922.16 ORX82671.1 - 1.3e-06 29.0 0.1 5.5e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 HMG_box PF00505.19 ORX82672.1 - 1.8e-24 85.9 3.4 1.8e-24 85.9 3.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX82672.1 - 6.2e-15 55.6 3.5 6.2e-15 55.6 3.5 1.6 2 0 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 ORX82672.1 - 0.015 15.8 5.6 0.015 15.8 5.6 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 ORX82672.1 - 0.21 12.1 6.6 0.057 14.0 3.2 1.7 1 1 1 2 2 2 0 YABBY protein Pkinase PF00069.25 ORX82673.1 - 2.4e-72 243.5 0.0 4.2e-71 239.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX82673.1 - 1e-39 136.4 0.0 2.2e-39 135.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 ORX82673.1 - 1.3e-11 44.1 0.7 4.7e-11 42.3 0.2 2.2 3 0 0 3 3 3 1 Kinase associated domain 1 Kinase-like PF14531.6 ORX82673.1 - 1.4e-08 34.4 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX82673.1 - 0.0019 17.2 0.2 0.0041 16.1 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORX82673.1 - 0.02 14.5 0.1 0.058 13.0 0.1 1.8 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 ORX82673.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX82673.1 - 0.066 12.5 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORX82674.1 - 4.6e-73 245.8 0.0 7e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX82674.1 - 4.3e-40 137.6 0.0 6.5e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORX82674.1 - 2.2e-10 40.1 0.1 4.1e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORX82674.1 - 1.1e-08 34.7 0.0 3.6e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX82674.1 - 0.0029 16.6 0.1 0.0051 15.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORX82674.1 - 0.022 14.3 0.2 0.062 12.9 0.2 1.6 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 ORX82674.1 - 0.061 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX82674.1 - 0.097 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FR47 PF08445.10 ORX82675.1 - 8.9e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORX82675.1 - 6e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORX82675.1 - 1.1e-05 25.2 0.1 1.6e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_1 PF00583.25 ORX82675.1 - 1.5e-05 25.2 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX82675.1 - 4.2e-05 23.9 0.1 8.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORX82675.1 - 0.00023 21.9 0.0 0.0004 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORX82675.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 ORX82675.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 ORX82675.1 - 0.035 14.2 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1525 PF07511.11 ORX82675.1 - 0.065 13.4 0.1 7.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) zf-H2C2_2 PF13465.6 ORX82676.1 - 1.3e-20 72.8 18.9 7.5e-08 32.5 0.0 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORX82676.1 - 5.6e-20 70.6 21.4 2.2e-06 27.8 1.7 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX82676.1 - 5.3e-11 42.4 19.7 0.0045 17.7 1.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORX82676.1 - 1.6e-07 31.8 4.5 0.2 12.3 0.1 4.0 1 1 3 4 4 4 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX82676.1 - 0.00045 20.4 4.2 1.8 8.9 0.1 3.9 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX82676.1 - 0.0012 19.1 7.1 0.058 13.7 0.3 2.5 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORX82676.1 - 0.0014 19.0 6.1 3.3 8.2 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORX82676.1 - 0.003 18.2 8.9 0.14 12.9 0.1 3.1 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2H2_11 PF16622.5 ORX82676.1 - 0.075 12.8 7.0 0.88 9.4 0.9 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORX82676.1 - 0.12 12.4 7.4 0.72 9.8 0.1 3.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX82676.1 - 0.27 11.0 0.4 0.27 11.0 0.4 4.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 ORX82676.1 - 1.8 8.7 10.7 13 5.9 0.4 3.6 1 1 3 4 4 4 0 Aberrant zinc-finger zf-CGNR PF11706.8 ORX82676.1 - 1.8 8.5 12.2 1.4 8.8 0.5 4.0 3 1 1 4 4 4 0 CGNR zinc finger SLAC1 PF03595.17 ORX82677.1 - 3.5e-70 236.8 42.5 4e-70 236.7 42.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3343 PF11823.8 ORX82677.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Isochorismatase PF00857.20 ORX82744.1 - 6.4e-14 52.5 0.1 7.1e-14 52.4 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family TMEM208_SND2 PF05620.11 ORX82745.1 - 6.6e-31 107.4 2.8 8.4e-31 107.0 2.8 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 UBA PF00627.31 ORX82746.1 - 1.5e-08 34.3 0.2 4.5e-08 32.8 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 ORX82746.1 - 0.00054 19.8 2.5 0.00054 19.8 2.5 3.5 2 1 0 3 3 3 2 STI1 domain DUF1365 PF07103.11 ORX82747.1 - 1.1e-40 139.8 0.0 2.8e-40 138.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) Zn_clus PF00172.18 ORX82748.1 - 3.5e-05 23.8 16.2 7.1e-05 22.8 16.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGAT PF03982.13 ORX82749.1 - 7.5e-104 346.8 0.0 9.8e-104 346.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase S6OS1 PF15676.5 ORX82749.1 - 0.57 8.6 2.0 0.76 8.2 2.0 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family DCP2 PF05026.13 ORX82751.1 - 9.3e-29 99.6 2.5 1.6e-28 98.9 2.5 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 ORX82751.1 - 7.7e-13 48.6 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PRP38 PF03371.15 ORX82752.1 - 2.3e-52 177.4 0.0 3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 PRP38 family NIF PF03031.18 ORX82753.1 - 1.9e-48 164.2 0.1 2.7e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Fer2 PF00111.27 ORX82754.1 - 2.2e-12 46.7 0.2 2.9e-12 46.4 0.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 ORX82754.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Magnetochrome domain G-patch PF01585.23 ORX82755.1 - 1.4e-15 56.9 0.3 2.5e-15 56.1 0.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORX82755.1 - 4.5e-07 29.9 0.1 4.5e-07 29.9 0.1 2.5 3 0 0 3 3 3 1 G-patch domain R3H PF01424.22 ORX82755.1 - 0.0043 17.0 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain PS_Dcarbxylase PF02666.15 ORX82756.1 - 9.1e-57 191.8 0.0 1.4e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ORX82756.1 - 1.2e-42 144.4 0.1 3e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 ORX82756.1 - 0.031 13.8 0.3 0.22 11.1 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 ORX82756.1 - 0.089 12.8 0.9 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 ORX82756.1 - 0.1 13.1 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Herpes_UL25 PF01499.16 ORX82757.1 - 0.013 14.1 7.1 0.02 13.4 7.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family BORCS8 PF10167.9 ORX82757.1 - 0.028 14.4 7.9 0.56 10.2 0.6 3.0 3 1 0 3 3 3 0 BLOC-1-related complex sub-unit 8 NPV_P10 PF05531.12 ORX82757.1 - 0.058 13.9 6.7 0.58 10.7 0.1 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HAP1_N PF04849.13 ORX82757.1 - 0.076 12.2 35.6 0.058 12.6 0.5 2.9 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Herpes_UL6 PF01763.16 ORX82757.1 - 0.11 11.0 12.3 0.06 11.9 9.5 1.7 1 1 1 2 2 2 0 Herpesvirus UL6 like MAD PF05557.13 ORX82757.1 - 0.58 8.5 34.0 0.93 7.8 29.4 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF948 PF06103.11 ORX82757.1 - 0.63 10.3 4.9 2.4 8.5 0.8 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Acyl-CoA_dh_2 PF08028.11 ORX82757.1 - 0.82 9.9 3.1 32 4.8 0.1 2.5 3 0 0 3 3 2 0 Acyl-CoA dehydrogenase, C-terminal domain Phage_GP20 PF06810.11 ORX82757.1 - 1.5 8.6 13.1 0.088 12.6 3.9 2.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 Peptidase_S64 PF08192.11 ORX82757.1 - 2.1 6.8 10.9 2.9 6.3 10.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 APG6_N PF17675.1 ORX82757.1 - 7.1 7.2 38.8 4.4 7.8 12.3 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region LMBR1 PF04791.16 ORX82757.1 - 7.6 5.3 17.4 49 2.7 17.4 2.1 1 1 0 1 1 1 0 LMBR1-like membrane protein GAS PF13851.6 ORX82757.1 - 9.4 5.5 32.2 0.089 12.1 2.0 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Fungal_trans PF04082.18 ORX82788.1 - 0.00042 19.4 0.4 0.00052 19.1 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORX82789.1 - 0.00039 19.5 2.3 0.001 18.2 0.4 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain ATP_bind_1 PF03029.17 ORX82789.1 - 0.012 15.4 1.1 0.02 14.7 1.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 ORX82790.1 - 2.3e-46 157.7 9.0 7.3e-25 88.1 0.1 4.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORX82790.1 - 5.6e-17 62.5 16.5 9.4e-07 28.9 5.0 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX82790.1 - 4.5e-13 49.1 6.4 0.0018 17.8 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 ORX82790.1 - 2.2e-08 34.0 3.8 2.2e-08 34.0 3.8 2.7 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 ORX82790.1 - 5.7e-08 32.4 2.3 0.00019 21.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX82790.1 - 1.9e-06 28.5 11.3 0.0069 16.9 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORX82790.1 - 1e-05 25.6 2.2 0.027 14.5 0.0 4.1 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.6 ORX82790.1 - 1.5e-05 25.3 1.6 0.27 11.5 0.2 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX82790.1 - 2.5e-05 24.2 0.3 0.26 11.2 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 ORX82790.1 - 0.0017 18.3 0.6 1.6 8.7 0.0 3.0 3 0 0 3 3 3 2 NACHT domain MeaB PF03308.16 ORX82790.1 - 0.0025 16.8 0.7 0.22 10.5 0.1 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 ORX82790.1 - 0.0053 16.8 2.2 3.8 7.6 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX82790.1 - 0.0056 17.1 3.5 0.37 11.2 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 ORX82790.1 - 0.0094 16.0 2.4 8.9 6.3 0.1 3.8 4 0 0 4 4 4 0 Dynamin family AAA_24 PF13479.6 ORX82790.1 - 0.0095 15.7 0.6 2.1 8.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 ORX82790.1 - 0.012 14.8 6.1 3.2 6.9 0.0 4.2 5 0 0 5 5 5 0 NB-ARC domain AAA_5 PF07728.14 ORX82790.1 - 0.039 13.9 0.3 12 5.9 0.1 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORX82790.1 - 0.053 13.9 0.0 19 5.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 ORX82790.1 - 0.083 12.4 0.2 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 ORX82790.1 - 0.084 12.8 0.4 12 5.8 0.2 2.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 ORX82790.1 - 0.2 11.8 2.1 4.8 7.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX82790.1 - 0.44 10.8 4.1 6.8 6.9 0.0 3.6 3 1 1 4 4 4 0 AAA domain AAA_15 PF13175.6 ORX82790.1 - 0.53 9.9 24.4 0.27 10.9 0.3 4.2 2 2 1 3 3 3 0 AAA ATPase domain OmpH PF03938.14 ORX82790.1 - 1.1 9.5 12.7 0.44 10.9 1.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 ORX82790.1 - 7 6.7 15.8 11 6.1 0.2 4.1 4 0 0 4 4 4 0 Helicase HerA, central domain SDH_alpha PF03313.15 ORX82791.1 - 2.3e-105 352.0 0.1 3.3e-105 351.5 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORX82791.1 - 1.7e-58 197.4 0.1 3.5e-58 196.4 0.1 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Tyrosinase PF00264.20 ORX82792.1 - 1.6e-35 123.4 4.5 1.4e-34 120.3 4.5 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase Pkinase PF00069.25 ORX82794.1 - 9.9e-73 244.7 0.0 1.2e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX82794.1 - 1.7e-50 171.8 0.0 2.1e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX82794.1 - 3.8e-05 22.6 0.0 6.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX82794.1 - 0.003 16.9 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX82794.1 - 0.035 13.1 0.1 6.3 5.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Atg8 PF02991.16 ORX82796.1 - 6.2e-52 174.1 0.2 7.3e-52 173.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORX82796.1 - 5.7e-06 26.6 0.0 7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Y_phosphatase PF00102.27 ORX82798.1 - 3.1e-08 33.5 0.0 3.9e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORX82798.1 - 1.5e-07 31.3 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORX82798.1 - 0.00025 20.8 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Aminotran_4 PF01063.19 ORX82799.1 - 1.4e-36 126.4 0.0 2.5e-36 125.6 0.0 1.4 2 0 0 2 2 2 1 Amino-transferase class IV HSF_DNA-bind PF00447.17 ORX82800.1 - 8.7e-34 116.0 0.8 1.6e-33 115.2 0.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding PI_PP_I PF18363.1 ORX82800.1 - 0.0076 16.4 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide phosphatase insertion domain F-box PF00646.33 ORX82801.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Transketolase_N PF00456.21 ORX82802.1 - 0.081 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain XAP5 PF04921.14 ORX82842.1 - 4.9e-77 259.1 16.0 8.3e-77 258.4 15.9 1.5 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 ORX82842.1 - 3.6 8.0 21.0 0.25 11.7 11.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) CKAP2_C PF15297.6 ORX82843.1 - 0.00098 18.3 0.2 0.00098 18.3 0.2 3.4 3 1 0 4 4 4 2 Cytoskeleton-associated protein 2 C-terminus EMP70 PF02990.16 ORX82844.1 - 2.6e-208 692.9 19.3 2.6e-208 692.9 19.3 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 ABC2_membrane PF01061.24 ORX82845.1 - 2e-89 298.6 63.0 2.4e-49 167.6 21.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORX82845.1 - 9.4e-40 136.3 0.1 3.2e-19 69.8 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORX82845.1 - 1.6e-25 88.8 3.5 1.5e-21 76.1 0.1 3.6 3 1 0 3 3 2 2 CDR ABC transporter RsgA_GTPase PF03193.16 ORX82845.1 - 2.5e-07 30.7 0.1 0.00021 21.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 ORX82845.1 - 7.5e-07 29.2 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 ORX82845.1 - 1.1e-05 25.9 0.0 0.0064 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORX82845.1 - 8.9e-05 22.2 0.1 0.0058 16.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX82845.1 - 9e-05 22.8 0.0 0.34 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORX82845.1 - 0.00011 22.6 0.0 0.023 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 ORX82845.1 - 0.00011 21.4 50.6 0.0018 17.4 18.0 2.8 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 ORX82845.1 - 0.00078 20.0 0.0 0.0026 18.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal MMR_HSR1 PF01926.23 ORX82845.1 - 0.0013 18.8 0.1 1.8 8.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 ORX82845.1 - 0.0014 18.3 0.0 0.0071 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX82845.1 - 0.007 16.5 0.0 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX82845.1 - 0.0089 15.8 0.2 1.5 8.5 0.4 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORX82845.1 - 0.018 14.7 0.1 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 ORX82845.1 - 0.023 14.6 0.1 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 ORX82845.1 - 0.024 14.4 0.1 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 ORX82845.1 - 0.026 14.8 0.1 0.25 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX82845.1 - 0.1 13.0 0.0 20 5.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 ORX82845.1 - 0.11 12.9 0.5 0.68 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORX82845.1 - 0.12 12.3 0.3 3.2 7.7 0.3 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ORX82845.1 - 0.12 12.8 0.1 38 4.7 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORX82845.1 - 0.13 12.7 0.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 ORX82845.1 - 0.21 10.2 0.4 2.1 6.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain Cyclin PF08613.11 ORX82846.1 - 7e-13 49.3 0.0 8.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX82846.1 - 6.4e-06 25.9 0.0 8.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RINGv PF12906.7 ORX82847.1 - 6.4e-13 48.6 3.2 1.4e-12 47.5 3.2 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORX82847.1 - 0.34 11.3 3.3 0.7 10.3 3.4 1.6 1 1 0 1 1 1 0 Ring finger domain Glyco_transf_34 PF05637.12 ORX82848.1 - 1.6e-44 152.4 0.8 1.3e-21 77.4 0.0 2.0 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORX82848.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 ORX82848.1 - 0.071 13.1 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF3405 PF11885.8 ORX82848.1 - 0.14 10.7 2.5 1.3 7.5 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3405) DUF3506 PF12014.8 ORX82849.1 - 5.8e-23 81.4 0.0 5.3e-21 75.1 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 ORX82849.1 - 1e-08 35.0 0.1 2.1e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX82849.1 - 0.004 17.0 0.2 0.004 17.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain Diphthami_syn_2 PF01902.17 ORX82850.1 - 1.4e-28 100.0 0.0 1.7e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase GPAT_N PF14829.6 ORX82850.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Ribonuc_L-PSP PF01042.21 ORX82851.1 - 3e-36 124.1 0.0 3.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GGDEF PF00990.21 ORX82851.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain EXS PF03124.14 ORX82852.1 - 4.8e-81 272.7 13.4 9.6e-72 242.1 8.6 2.0 1 1 1 2 2 2 2 EXS family zf-4CXXC_R1 PF10497.9 ORX82853.1 - 1.5e-29 102.1 8.1 2.3e-29 101.5 8.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Chitin_synth_2 PF03142.15 ORX82854.1 - 5.9e-282 936.0 0.2 8.8e-282 935.4 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX82854.1 - 2.1e-14 54.0 0.0 7.8e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX82854.1 - 7.9e-11 42.2 9.1 7.9e-11 42.2 9.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX82854.1 - 0.00033 20.2 0.5 0.05 13.1 0.1 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX82854.1 - 0.17 11.7 0.0 0.51 10.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 RhoGEF PF00621.20 ORX82856.1 - 7.9e-41 140.3 1.6 1.6e-40 139.3 1.6 1.5 1 0 0 1 1 1 1 RhoGEF domain CBP_CCPA PF17040.5 ORX82857.1 - 0.0051 17.4 0.4 0.0066 17.0 0.4 1.1 1 0 0 1 1 1 1 Cellulose-complementing protein A DUF2521 PF10730.9 ORX82858.1 - 0.035 14.1 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Chitin_synth_2 PF03142.15 ORX82890.1 - 3.6e-68 230.5 2.1 9.3e-39 133.4 0.0 2.6 2 1 0 2 2 2 2 Chitin synthase Phage_holin_3_6 PF07332.11 ORX82890.1 - 0.03 14.3 0.6 0.063 13.3 0.6 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Chitin_synth_2 PF03142.15 ORX82891.1 - 5.7e-126 421.2 0.0 7.3e-126 420.9 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX82891.1 - 4.1e-12 46.5 0.1 5.5e-08 33.0 0.0 3.0 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX82891.1 - 7.2e-12 45.6 5.0 1.5e-11 44.6 5.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX82891.1 - 2.7e-05 24.1 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX82891.1 - 0.0084 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF981 PF06168.11 ORX82891.1 - 1.5 8.7 8.4 3.5 7.5 8.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF981) adh_short PF00106.25 ORX82892.1 - 1e-25 90.4 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX82892.1 - 5.2e-23 81.8 0.2 9.9e-23 80.9 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX82892.1 - 5.3e-08 33.0 0.1 8e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX82892.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX82892.1 - 0.033 13.3 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1419 PF07215.11 ORX82892.1 - 0.095 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) PP2C PF00481.21 ORX82893.1 - 5.1e-69 232.8 0.0 6.1e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C HpcH_HpaI PF03328.14 ORX82894.1 - 5.3e-53 179.4 0.8 6.7e-53 179.1 0.8 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ORX82894.1 - 8.1e-16 58.1 0.3 2.2e-11 43.5 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 ORX82894.1 - 0.005 15.8 0.4 0.0067 15.4 0.4 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Ribosomal_S13_N PF08069.12 ORX82895.1 - 7.8e-32 109.1 0.1 1.5e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORX82895.1 - 3.3e-14 52.9 0.6 4.8e-14 52.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HTH_32 PF13565.6 ORX82895.1 - 0.071 13.7 0.2 0.17 12.5 0.0 1.7 2 1 0 2 2 2 0 Homeodomain-like domain PAX PF00292.18 ORX82895.1 - 0.092 12.7 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain ELYS PF13934.6 ORX82896.1 - 2.3e-44 152.0 6.7 3.6e-44 151.4 6.7 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly CytochromB561_N PF09786.9 ORX82897.1 - 7.7e-47 160.6 4.8 5.3e-46 157.8 0.0 3.0 2 1 0 2 2 2 1 Cytochrome B561, N terminal NPCC PF08058.11 ORX82897.1 - 4.8e-10 39.6 0.0 2.9e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 Nuclear pore complex component Tim17 PF02466.19 ORX82898.1 - 6.6e-15 55.4 0.6 1.4e-14 54.4 0.5 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family CSN8_PSD8_EIF3K PF10075.9 ORX82899.1 - 3.1e-33 114.8 0.1 4.5e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 ORX82899.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family PASTA PF03793.19 ORX82899.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 PASTA domain PCI PF01399.27 ORX82899.1 - 0.096 13.2 0.2 1.3 9.6 0.1 2.5 2 1 0 2 2 2 0 PCI domain Ribosomal_L27A PF00828.19 ORX82900.1 - 4.1e-21 76.0 0.2 5.8e-21 75.5 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CLPTM1 PF05602.12 ORX82900.1 - 0.24 10.4 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) PIP5K PF01504.18 ORX82901.1 - 5e-97 324.4 0.1 7.4e-97 323.8 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase pP_pnuc_1 PF18165.1 ORX82901.1 - 0.036 13.9 0.1 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease ATP-synt_G PF04718.15 ORX82902.1 - 5.3e-19 68.9 0.8 9.3e-19 68.1 0.4 1.6 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit NAD_binding_10 PF13460.6 ORX82902.1 - 0.028 14.3 0.1 0.037 13.9 0.1 1.3 1 1 0 1 1 1 0 NAD(P)H-binding DUF2800 PF10926.8 ORX82902.1 - 0.038 13.3 0.4 0.045 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) GHL13 PF14883.6 ORX82902.1 - 0.09 11.8 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 CIDE-N PF02017.15 ORX82902.1 - 0.12 12.4 0.1 0.34 11.0 0.1 1.7 2 0 0 2 2 2 0 CIDE-N domain Kinesin PF00225.23 ORX82903.1 - 4.2e-98 328.3 0.1 4.2e-98 328.3 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORX82903.1 - 2.5e-17 63.2 0.0 1.3e-16 60.8 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding DUF4407 PF14362.6 ORX82903.1 - 0.13 11.6 27.3 0.097 12.0 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 ORX82903.1 - 5.5 7.4 37.5 3.5 8.0 21.8 2.6 2 0 0 2 2 2 0 Fez1 LSM PF01423.22 ORX82904.1 - 9.6e-19 66.9 0.0 1.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX82904.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_L18A PF01775.17 ORX82905.1 - 4.6e-54 181.7 0.2 6e-54 181.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A zf-Tim10_DDP PF02953.15 ORX82906.1 - 2.8e-19 68.5 5.5 3.9e-19 68.1 5.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 ORX82906.1 - 0.00037 20.7 0.4 0.0026 18.0 0.0 2.0 1 1 1 2 2 2 1 Phasin protein Cyclin_C PF02984.19 ORX82906.1 - 0.061 13.4 0.3 0.087 12.9 0.3 1.4 1 1 0 1 1 1 0 Cyclin, C-terminal domain HpaB_N PF11794.8 ORX82906.1 - 0.062 13.0 0.4 0.067 12.9 0.4 1.0 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF2116 PF09889.9 ORX82906.1 - 0.74 9.8 6.2 0.34 10.9 1.0 2.3 1 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BSD PF03909.17 ORX82907.1 - 4.1e-14 52.3 1.2 9.3e-14 51.2 1.2 1.7 1 0 0 1 1 1 1 BSD domain Pollen_allerg_2 PF01620.16 ORX82907.1 - 0.11 12.7 0.2 0.31 11.2 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) DUF2849 PF11011.8 ORX82907.1 - 4.5 8.0 7.3 54 4.5 2.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2849) SAP18 PF06487.12 ORX82907.1 - 5 7.3 7.4 5.5 7.2 2.1 2.7 1 1 1 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) GTP_EFTU PF00009.27 ORX82908.1 - 5.8e-65 218.5 0.1 9.2e-65 217.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 ORX82908.1 - 1.2e-28 99.0 0.0 3e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORX82908.1 - 4.8e-20 71.4 0.0 1.4e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORX82908.1 - 5e-11 42.8 0.3 1.9e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 ORX82908.1 - 1e-07 31.8 0.1 6.7e-06 25.9 0.1 2.5 1 1 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 ORX82908.1 - 6e-07 29.3 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORX82908.1 - 0.00022 21.3 0.1 0.00051 20.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pombe_5TM PF09437.10 ORX82908.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Pombe specific 5TM protein Chorismate_synt PF01264.21 ORX82909.1 - 7.5e-141 468.6 0.1 8.7e-141 468.4 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase SKG6 PF08693.10 ORX82910.1 - 1.8e-06 27.2 1.5 2.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.10 ORX82910.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM51 PF15345.6 ORX82910.1 - 0.003 17.4 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Glycophorin_A PF01102.18 ORX82910.1 - 0.0037 17.5 0.0 0.0049 17.1 0.0 1.1 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 ORX82910.1 - 0.046 13.6 0.2 0.09 12.7 0.2 1.4 1 1 0 1 1 1 0 TMEM154 protein family EssA PF10661.9 ORX82910.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF2207 PF09972.9 ORX82910.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gram_pos_anchor PF00746.21 ORX82910.1 - 1.7 8.7 3.6 12 5.9 3.6 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif WD40 PF00400.32 ORX82911.1 - 7.3e-45 150.0 39.8 8.7e-09 35.9 0.5 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 ORX82911.1 - 1.2e-12 47.3 9.0 0.017 13.8 0.0 5.9 2 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.7 ORX82911.1 - 8.5e-12 44.8 0.1 2.8e-11 43.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX82911.1 - 1.7e-08 34.6 3.3 0.1 12.9 0.0 6.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX82911.1 - 2.9e-07 30.2 0.3 8e-07 28.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 ORX82911.1 - 0.00042 20.3 0.2 18 5.4 0.0 4.6 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 ORX82911.1 - 0.00089 18.7 0.8 0.0014 18.1 0.2 1.5 2 0 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 ORX82911.1 - 0.013 15.3 0.2 0.44 10.4 0.0 3.2 2 1 1 3 3 3 0 F-box ERG4_ERG24 PF01222.17 ORX82951.1 - 1.5e-135 452.3 10.1 2.1e-135 451.9 10.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORX82951.1 - 0.0025 17.4 1.0 0.008 15.7 1.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ABC_tran PF00005.27 ORX82952.1 - 1.3e-52 177.9 0.0 9.3e-29 100.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORX82952.1 - 1.9e-26 93.4 11.1 6.3e-19 68.7 2.3 2.7 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ORX82952.1 - 7.7e-08 32.0 4.1 0.0033 16.9 0.0 3.6 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORX82952.1 - 2e-07 31.1 2.9 0.0063 16.6 0.3 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX82952.1 - 3e-05 24.0 2.4 0.0017 18.3 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORX82952.1 - 6.2e-05 22.7 1.3 0.14 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORX82952.1 - 0.00014 22.0 1.1 0.00014 22.0 1.1 3.5 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.12 ORX82952.1 - 0.0014 17.9 0.6 0.12 11.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 ORX82952.1 - 0.0032 17.3 1.2 1.4 8.6 0.0 3.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORX82952.1 - 0.0035 17.1 2.3 0.44 10.2 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORX82952.1 - 0.005 17.4 9.9 0.6 10.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 ORX82952.1 - 0.0068 16.8 0.1 2.1 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 ORX82952.1 - 0.01 16.0 0.5 6 7.1 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORX82952.1 - 0.015 14.9 0.5 5.4 6.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORX82952.1 - 0.059 12.7 0.7 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 ORX82952.1 - 0.064 12.0 0.1 5.2 5.8 0.1 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 ORX82952.1 - 0.079 12.5 1.0 2.9 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 ORX82952.1 - 0.086 11.9 0.2 0.76 8.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 ORX82952.1 - 0.11 11.5 1.0 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ORX82952.1 - 0.12 11.9 1.0 0.5 9.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 ORX82952.1 - 0.18 11.0 1.3 11 5.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IIGP PF05049.13 ORX82952.1 - 0.28 10.2 3.3 2.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 ORX82952.1 - 0.42 10.9 2.7 6 7.2 0.3 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORX82952.1 - 1 9.4 10.6 1.3 9.0 0.5 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 ORX82952.1 - 7.6 6.1 11.8 7.4 6.2 0.2 3.2 2 1 1 3 3 3 0 AAA ATPase domain Septin PF00735.18 ORX82952.1 - 8.1 5.6 8.0 27 3.9 0.2 3.1 3 0 0 3 3 3 0 Septin Mg_trans_NIPA PF05653.14 ORX82953.1 - 2.4e-64 217.3 16.4 2.4e-60 204.2 12.9 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORX82953.1 - 6.3e-05 23.2 1.4 6.3e-05 23.2 1.4 4.0 3 1 0 3 3 3 1 EamA-like transporter family DUF4131 PF13567.6 ORX82953.1 - 1.2 8.7 10.0 0.96 9.1 0.4 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) SRA1 PF07304.11 ORX82954.1 - 3.4e-15 56.1 1.3 1.5e-14 54.0 0.0 2.7 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 ORX82954.1 - 2e-09 37.9 6.2 0.11 13.3 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Prp18 PF02840.15 ORX82954.1 - 4e-05 23.7 0.0 9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain Sec16_C PF12931.7 ORX82954.1 - 0.0049 16.6 0.1 0.062 12.9 0.1 2.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DUF641 PF04859.12 ORX82955.1 - 0.014 15.8 2.1 0.018 15.3 1.9 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) COG2 PF06148.11 ORX82955.1 - 0.025 14.6 0.9 0.03 14.4 0.9 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 ORX82955.1 - 0.028 12.4 2.7 0.033 12.2 2.7 1.0 1 0 0 1 1 1 0 Prominin DUF1647 PF07801.11 ORX82955.1 - 0.16 11.7 0.7 0.21 11.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) LcrG PF07216.12 ORX82955.1 - 0.25 11.3 4.0 0.13 12.2 1.3 1.8 2 0 0 2 2 2 0 LcrG protein Pkinase_Tyr PF07714.17 ORX82956.1 - 2.4e-52 177.8 0.0 2.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORX82956.1 - 2e-50 171.6 0.0 2.8e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SAP PF02037.27 ORX82956.1 - 9.9e-08 31.6 0.1 2.1e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain APH PF01636.23 ORX82956.1 - 0.031 14.2 0.1 0.55 10.1 0.0 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family LETM1 PF07766.13 ORX82956.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 LETM1-like protein NTPase_I-T PF01931.18 ORX82957.1 - 3e-54 183.2 0.0 3.3e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF3236 PF11576.8 ORX82957.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DUF727 PF05303.12 ORX82958.1 - 4.1e-06 26.8 0.1 6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) E1-E2_ATPase PF00122.20 ORX82959.1 - 1.4e-34 119.2 0.1 1.4e-34 119.2 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 ORX82959.1 - 3e-24 85.5 6.2 1.5e-23 83.2 4.7 2.9 2 1 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.26 ORX82959.1 - 2.6e-13 50.8 0.0 0.0012 19.1 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX82959.1 - 2.1e-06 27.3 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 ORX82959.1 - 7.3e-05 22.6 10.1 7.3e-05 22.6 10.1 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX82959.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX82959.1 - 0.23 11.2 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_S9 PF00380.19 ORX82960.1 - 5.5e-34 117.3 0.1 6.2e-34 117.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 IF4E PF01652.18 ORX82961.1 - 3.8e-46 156.8 4.7 4.8e-46 156.5 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CDP-OH_P_transf PF01066.21 ORX82962.1 - 9.6e-15 55.1 0.6 9.6e-15 55.1 0.6 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cupin_2 PF07883.11 ORX82963.1 - 9.9e-07 28.4 0.3 1.6e-06 27.8 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ORX82963.1 - 1.1e-05 25.1 0.1 2.4e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Cupin Cupin_6 PF12852.7 ORX82963.1 - 0.0026 17.5 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ORX82963.1 - 0.0032 17.4 0.2 0.005 16.8 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ORX82963.1 - 0.0085 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 ORX82963.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 ARD/ARD' family Aa_trans PF01490.18 ORX82964.1 - 4.4e-79 266.1 34.3 5.1e-79 265.9 34.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PRIMA1 PF16101.5 ORX82964.1 - 1.4 9.0 0.0 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 PAD_porph PF04371.15 ORX82965.1 - 1.2e-106 356.6 0.0 1.4e-106 356.4 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase NIF PF03031.18 ORX82998.1 - 5.9e-42 143.1 0.0 7.3e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NIF PF03031.18 ORX82999.1 - 5.6e-46 156.1 0.0 7e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Myb_DNA-bind_6 PF13921.6 ORX83000.1 - 8.7e-13 48.3 0.0 8.2e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX83000.1 - 7.1e-12 45.3 0.0 8.3e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORX83000.1 - 0.089 12.7 2.0 0.17 11.8 0.0 2.5 2 1 1 3 3 3 0 Myb DNA-binding like UDPGP PF01704.18 ORX83001.1 - 1.4e-196 653.0 0.6 1.6e-196 652.8 0.6 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MaoC_dehydratas PF01575.19 ORX83002.1 - 7e-12 45.0 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Nrap_D4 PF17405.2 ORX83004.1 - 3.6e-60 203.0 0.0 6.2e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 ORX83004.1 - 1.6e-48 164.5 0.0 7.3e-48 162.4 0.0 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 ORX83004.1 - 2.3e-48 164.1 0.9 3.4e-48 163.5 0.2 1.7 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D2 PF17403.2 ORX83004.1 - 2.8e-47 160.3 0.0 2.1e-45 154.2 0.0 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 ORX83004.1 - 1.2e-40 139.2 0.0 2.5e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 ORX83004.1 - 3.2e-35 121.3 0.0 6.8e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 SF3a60_bindingd PF12108.8 ORX83004.1 - 0.075 12.9 0.6 0.25 11.3 0.6 1.9 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Herpes_UL55 PF04537.12 ORX83004.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein DUF3658 PF12395.8 ORX83004.1 - 0.26 11.2 1.4 5 7.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function HSP70 PF00012.20 ORX83005.1 - 9.2e-244 810.1 7.6 1e-243 810.0 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX83005.1 - 1.8e-19 69.8 0.3 2.7e-18 65.9 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 ORX83005.1 - 0.0068 15.4 0.3 0.053 12.5 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 ORX83005.1 - 0.011 15.1 0.4 0.033 13.4 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 ORX83005.1 - 0.029 13.6 0.0 0.079 12.2 0.0 1.7 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.16 ORX83005.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain zf-ZPR1 PF03367.13 ORX83005.1 - 0.13 12.1 0.4 0.34 10.7 0.4 1.7 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Complex1_LYR PF05347.15 ORX83005.1 - 0.24 11.5 1.4 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Complex 1 protein (LYR family) FtsA PF14450.6 ORX83005.1 - 0.32 11.4 2.8 19 5.8 0.1 3.1 3 2 0 3 3 3 0 Cell division protein FtsA Flagellin_N PF00669.20 ORX83005.1 - 1.4 9.0 7.3 0.42 10.7 4.0 1.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Pribosyltran PF00156.27 ORX83006.1 - 8.3e-17 61.2 0.1 1.1e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORX83006.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.6 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Complex1_LYR PF05347.15 ORX83007.1 - 9.6e-13 48.0 2.2 1.3e-12 47.6 2.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORX83007.1 - 2.9e-07 31.1 0.3 4.2e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Prominin PF05478.11 ORX83007.1 - 0.12 10.4 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Prominin tRNA-synt_1b PF00579.25 ORX83008.1 - 3.3e-78 263.0 0.0 4.7e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ORX83008.1 - 9.5e-10 38.0 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 ORX83008.1 - 9.1e-09 35.2 0.4 2.8e-06 27.2 0.3 3.1 2 1 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain EMP24_GP25L PF01105.24 ORX83009.1 - 1.2e-46 158.9 0.1 1.4e-46 158.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 ORX83009.1 - 0.031 14.7 0.1 0.048 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) S4 PF01479.25 ORX83010.1 - 2.3e-14 52.8 0.0 3.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 S4 domain NIF PF03031.18 ORX83011.1 - 2.6e-45 154.0 0.0 5.8e-45 152.8 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Remorin_C PF03763.13 ORX83011.1 - 1.3 8.9 12.3 0.15 11.9 7.9 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region Fibrillarin PF01269.17 ORX83012.1 - 1.7e-107 357.7 0.0 2.1e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORX83012.1 - 7.5e-07 29.1 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORX83012.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORX83012.1 - 0.098 12.3 0.0 1 9.0 0.0 2.0 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORX83012.1 - 0.19 11.8 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DASH_Dad1 PF08649.10 ORX83013.1 - 0.012 15.8 0.1 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad1 HemS PF05171.12 ORX83013.1 - 0.026 14.5 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain AAA_32 PF13654.6 ORX83013.1 - 0.19 10.5 14.4 0.28 9.9 14.4 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 ORX83013.1 - 1.8 8.7 7.7 0.22 11.7 0.3 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HSF_DNA-bind PF00447.17 ORX83014.1 - 4.7e-33 113.7 1.7 4.7e-33 113.7 1.7 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding ATG16 PF08614.11 ORX83014.1 - 0.0011 19.2 1.0 0.002 18.4 1.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PPP4R2 PF09184.11 ORX83014.1 - 0.003 17.2 2.0 0.018 14.6 0.2 2.1 2 0 0 2 2 2 1 PPP4R2 DHR10 PF18595.1 ORX83014.1 - 0.024 14.7 5.1 0.035 14.2 5.1 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 ORX83014.1 - 0.068 13.3 1.2 0.095 12.8 1.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 ORX83014.1 - 0.079 13.0 1.0 0.14 12.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 ORX83014.1 - 0.17 12.0 0.8 0.26 11.4 0.8 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TMPIT PF07851.13 ORX83014.1 - 3 7.0 5.4 0.78 8.9 2.5 1.4 2 0 0 2 2 2 0 TMPIT-like protein DJ-1_PfpI PF01965.24 ORX83077.1 - 1.2e-08 34.9 0.0 2.7e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX83077.1 - 0.00069 19.4 0.0 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX83077.1 - 0.0024 17.6 0.0 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX83078.1 - 2e-08 34.2 0.0 7.6e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX83078.1 - 0.0011 18.7 0.1 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX83078.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Latrotoxin C-terminal domain RICTOR_N PF14664.6 ORX83079.1 - 0.17 10.8 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Myticin-prepro PF10690.9 ORX83083.1 - 0.0034 17.6 0.3 0.0057 16.9 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel DUF4597 PF15366.6 ORX83084.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Myticin-prepro PF10690.9 ORX83085.1 - 0.0095 16.2 0.6 0.0095 16.2 0.6 1.7 2 0 0 2 2 2 1 Myticin pre-proprotein from the mussel Abhydrolase_1 PF00561.20 ORX83085.1 - 0.08 12.6 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Toxin_TOLIP PF00087.21 ORX83088.1 - 0.58 10.5 7.5 1.9 8.8 0.7 2.5 2 0 0 2 2 2 0 Snake toxin and toxin-like protein Chlam_OMP3 PF03503.13 ORX83088.1 - 0.76 10.1 5.7 0.11 12.8 1.4 1.8 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 Glyco_hydro_32N PF00251.20 ORX83119.1 - 1.4e-14 54.4 0.5 1.6e-14 54.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HAD_2 PF13419.6 ORX83120.1 - 1e-25 90.8 0.0 1.3e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX83120.1 - 3.9e-17 63.3 0.3 7.9e-14 52.4 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX83120.1 - 3.7e-08 33.3 0.0 9.8e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORX83120.1 - 0.00036 21.0 0.0 0.00069 20.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Chitin_synth_2 PF03142.15 ORX83151.1 - 3.1e-253 841.2 0.0 4.6e-253 840.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX83151.1 - 3e-14 53.5 0.0 6.8e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX83151.1 - 1.7e-13 50.9 7.5 7.4e-13 48.8 7.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX83151.1 - 0.0061 16.1 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX83151.1 - 0.014 15.2 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Gp_dh_C PF02800.20 ORX83152.1 - 9.2e-72 239.8 0.0 1.3e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORX83152.1 - 4.2e-40 136.2 0.1 7.9e-40 135.3 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX83152.1 - 0.026 14.7 0.2 0.18 11.9 0.1 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus CPSase_L_D2 PF02786.17 ORX83153.1 - 2.7e-80 268.8 0.2 4.7e-80 268.1 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORX83153.1 - 2.6e-71 239.5 0.0 3.9e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORX83153.1 - 9e-37 126.0 0.1 1.9e-36 124.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORX83153.1 - 4.8e-31 107.0 0.0 1.2e-30 105.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ORX83153.1 - 4.1e-30 105.2 0.0 9e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ORX83153.1 - 5.6e-18 64.5 5.1 6.2e-17 61.2 3.6 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORX83153.1 - 6e-08 32.5 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORX83153.1 - 7.6e-07 28.9 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORX83153.1 - 6e-06 26.0 0.3 0.0036 17.1 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 ORX83153.1 - 4.1e-05 24.2 1.6 0.21 12.3 0.0 3.8 4 0 0 4 4 3 2 HlyD family secretion protein NQRA PF05896.11 ORX83153.1 - 0.0013 18.3 0.2 0.0025 17.3 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_3 PF02655.14 ORX83153.1 - 0.0016 18.5 0.0 0.0044 17.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 ORX83153.1 - 0.0043 16.3 0.6 0.19 10.9 0.0 2.6 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 ORX83153.1 - 0.0074 15.9 0.0 0.28 10.8 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain DUF2118 PF09891.9 ORX83153.1 - 0.064 13.2 0.1 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 ORX83153.1 - 0.076 12.2 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 ORX83153.1 - 0.15 12.0 1.7 0.3 11.1 0.8 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 ORX83153.1 - 0.16 11.8 1.4 0.91 9.4 0.4 2.7 3 0 0 3 3 2 0 Glycine cleavage H-protein BIR PF00653.21 ORX83154.1 - 0.22 12.2 0.7 0.72 10.6 0.2 2.0 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Inp1 PF12634.7 ORX83155.1 - 0.00096 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Band_7 PF01145.25 ORX83191.1 - 3.6e-26 92.3 1.4 4.9e-26 91.8 1.4 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX83191.1 - 0.041 13.6 0.2 0.085 12.5 0.1 1.6 1 1 1 2 2 2 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORX83191.1 - 0.062 12.9 0.1 0.079 12.5 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Peptidase_M28 PF04389.17 ORX83192.1 - 4.1e-36 124.5 0.0 7.4e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ORX83192.1 - 0.00019 20.6 0.0 0.00087 18.4 0.0 1.8 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORX83192.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4508 PF14969.6 ORX83194.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) ER_lumen_recept PF00810.18 ORX83195.1 - 9.1e-54 182.3 9.2 1.6e-53 181.5 9.2 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORX83195.1 - 1.7e-06 27.7 6.0 0.43 10.4 0.2 4.2 3 1 1 4 4 4 3 PQ loop repeat Autophagy_N PF03986.13 ORX83196.1 - 8.6e-50 168.2 2.9 3e-49 166.5 2.9 1.9 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 ORX83196.1 - 7e-20 71.4 0.5 1.6e-19 70.2 0.5 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 ORX83196.1 - 4.6e-15 54.8 4.4 9.6e-15 53.8 4.4 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ETF PF01012.21 ORX83197.1 - 4.9e-49 166.7 0.5 6.1e-49 166.4 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Dabb PF07876.12 ORX83197.1 - 0.067 13.8 0.0 0.19 12.4 0.0 1.8 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain RNase_P_Rpp14 PF01900.19 ORX83199.1 - 1e-05 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Pfk_N PF18468.1 ORX83199.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast Pkinase PF00069.25 ORX83200.1 - 7.8e-66 222.1 0.0 9.1e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX83200.1 - 7.3e-34 117.2 0.0 9.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX83200.1 - 3.9e-10 39.5 0.0 2.6e-06 27.0 0.0 2.3 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 ORX83200.1 - 8.8e-05 22.5 0.1 0.00057 19.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX83200.1 - 0.00075 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORX83200.1 - 0.00083 19.0 0.1 0.86 9.2 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORX83200.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX83200.1 - 0.0039 16.8 0.1 0.017 14.8 0.0 1.8 1 1 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 ORX83200.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORX83200.1 - 0.029 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Transposase_24 PF03004.14 ORX83201.1 - 0.023 14.8 2.1 0.029 14.5 2.1 1.2 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF5517 PF17639.2 ORX83201.1 - 0.061 13.6 1.6 0.81 10.0 0.2 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5517) PPL5 PF18168.1 ORX83201.1 - 0.075 12.3 2.8 0.089 12.1 2.8 1.0 1 0 0 1 1 1 0 Prim-pol family 5 BCDHK_Adom3 PF10436.9 ORX83202.1 - 1.7e-43 148.2 1.7 3e-43 147.5 1.7 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX83202.1 - 1.4e-09 38.4 0.0 3.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORX83202.1 - 0.00079 19.3 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glutaredoxin PF00462.24 ORX83202.1 - 0.15 12.3 0.1 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Glutaredoxin Bestrophin PF01062.21 ORX83203.1 - 8.2e-47 160.0 0.8 1.1e-46 159.6 0.8 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3262 PF11660.8 ORX83203.1 - 0.028 14.8 0.7 0.1 13.0 0.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) FA_desaturase PF00487.24 ORX83204.1 - 3.2e-40 138.6 9.9 4.5e-40 138.1 9.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORX83204.1 - 1.6e-16 60.2 0.1 3.1e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ApbA PF02558.16 ORX83206.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BAP PF06639.11 ORX83247.1 - 0.063 13.6 3.5 1 9.8 0.1 3.3 3 0 0 3 3 3 0 Basal layer antifungal peptide (BAP) Aldo_ket_red PF00248.21 ORX83248.1 - 6.6e-27 94.5 0.0 6.9e-25 87.8 0.0 2.5 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_14 PF13428.6 ORX83249.1 - 0.065 14.1 0.0 23 6.2 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat IKBKB_SDD PF18397.1 ORX83251.1 - 0.0011 18.4 1.6 0.0014 17.9 1.6 1.1 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain DUF501 PF04417.12 ORX83251.1 - 3.7 7.4 5.5 19 5.0 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF501) Forkhead PF00250.18 ORX83252.1 - 2.6e-31 107.7 0.3 3.4e-31 107.3 0.3 1.2 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 ORX83252.1 - 0.16 12.4 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family TPR_MLP1_2 PF07926.12 ORX83254.1 - 2.1e-30 105.4 25.1 2.1e-30 105.4 25.1 16.9 7 4 9 16 16 16 8 TPR/MLP1/MLP2-like protein RBD-FIP PF09457.10 ORX83254.1 - 0.035 14.0 5.7 0.089 12.7 2.5 3.7 2 0 0 2 2 2 0 FIP domain DUF3614 PF12267.8 ORX83254.1 - 0.74 10.3 2.8 7.8 7.0 2.8 2.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Pkinase PF00069.25 ORX83255.1 - 1e-27 97.2 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX83255.1 - 4.1e-16 59.0 0.0 6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX83255.1 - 4.9e-08 32.2 0.1 4.9e-08 32.2 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORX83255.1 - 0.015 14.3 0.2 0.023 13.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORX83255.1 - 0.037 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family bZIP_1 PF00170.21 ORX83256.1 - 1.2e-05 25.2 17.7 1.2e-05 25.2 17.7 3.4 3 1 1 4 4 4 2 bZIP transcription factor CIAPIN1 PF05093.13 ORX83256.1 - 0.1 13.1 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MAGE_N PF12440.8 ORX83256.1 - 0.12 13.1 0.1 0.12 13.1 0.1 2.9 2 2 1 3 3 3 0 Melanoma associated antigen family N terminal YabA PF06156.13 ORX83256.1 - 0.43 11.2 7.7 0.16 12.6 4.9 1.7 2 0 0 2 2 2 0 Initiation control protein YabA eIF3_subunit PF08597.10 ORX83256.1 - 0.6 10.0 10.0 0.35 10.7 7.6 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit NADH-G_4Fe-4S_3 PF10588.9 ORX83256.1 - 0.8 9.3 3.7 13 5.4 0.4 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF4446 PF14584.6 ORX83256.1 - 0.99 9.4 4.1 1.7 8.6 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) bZIP_2 PF07716.15 ORX83256.1 - 1.8 8.7 20.1 5.1 7.3 16.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 ORX83256.1 - 5.7 7.3 10.2 1.7 9.1 4.5 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family AAA PF00004.29 ORX83257.1 - 1.7e-18 67.4 0.0 3.8e-18 66.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX83257.1 - 2.5e-14 54.0 0.0 1.3e-13 51.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX83257.1 - 6.3e-13 49.2 0.0 1.6e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 ORX83257.1 - 4.3e-12 45.9 0.3 2.3e-11 43.5 0.1 2.3 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 ORX83257.1 - 2.9e-10 40.2 0.0 9.2e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 ORX83257.1 - 2.5e-05 24.2 0.0 6.5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 ORX83257.1 - 0.00026 21.4 0.1 0.0051 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORX83257.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ORX83257.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_3 PF07726.11 ORX83257.1 - 0.014 15.2 0.0 3.3 7.6 0.0 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ORX83257.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 ORX83257.1 - 0.043 14.0 0.0 0.13 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORX83257.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Microtub_bd PF16796.5 ORX83257.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding Glutaminase PF04960.15 ORX83257.1 - 0.089 12.0 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Glutaminase AAA_30 PF13604.6 ORX83257.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORX83257.1 - 0.16 12.0 0.0 0.82 9.7 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 ORX83257.1 - 0.2 11.6 0.6 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 ORX83257.1 - 0.22 11.9 0.3 0.92 9.9 0.0 2.3 3 0 0 3 3 2 0 RNA helicase BORCS6 PF10157.9 ORX83259.1 - 6.2e-20 72.0 0.1 6.6e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Spc7 PF08317.11 ORX83259.1 - 0.0012 17.8 1.6 0.0013 17.7 1.6 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF948 PF06103.11 ORX83259.1 - 0.0034 17.6 0.8 0.051 13.8 0.8 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 ORX83259.1 - 0.0076 16.3 0.3 0.01 15.9 0.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 ORX83259.1 - 0.01 16.1 2.8 0.038 14.3 0.2 2.2 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NBD94 PF16830.5 ORX83259.1 - 0.03 14.7 0.4 0.3 11.5 0.1 2.1 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH DUF1664 PF07889.12 ORX83259.1 - 0.048 13.7 1.1 0.13 12.3 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 ORX83259.1 - 0.051 13.4 0.0 0.054 13.3 0.0 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Gag_p15 PF08723.10 ORX83259.1 - 0.078 13.2 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Gag protein p15 DUF725 PF05267.12 ORX83259.1 - 0.081 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF725) SIKE PF05769.11 ORX83259.1 - 0.28 11.1 3.9 3 7.8 0.7 2.0 1 1 1 2 2 2 0 SIKE family LPP PF04728.13 ORX83259.1 - 0.49 10.8 2.1 17 5.9 0.3 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper MRP-S26 PF14943.6 ORX83308.1 - 0.043 13.7 12.0 8.2 6.3 12.0 2.5 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 CPSase_L_D2 PF02786.17 ORX83309.1 - 6.5e-115 381.9 0.2 4.2e-83 278.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 ORX83309.1 - 2e-50 169.9 0.0 4.6e-50 168.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORX83309.1 - 3.1e-48 164.1 0.0 6.6e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 ORX83309.1 - 1.7e-41 141.4 0.0 4e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 ORX83309.1 - 1e-25 90.6 0.2 3.3e-25 89.0 0.2 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 ORX83309.1 - 3.5e-21 75.2 0.0 2.5e-20 72.4 0.0 2.7 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ORX83309.1 - 2.8e-17 62.9 1.1 3.4e-08 33.3 0.1 2.8 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORX83309.1 - 3.8e-14 52.6 0.0 1.2e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORX83309.1 - 1.6e-10 40.9 0.1 5.5e-05 22.9 0.0 3.0 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ORX83309.1 - 0.00017 21.6 1.5 0.34 10.9 0.1 3.2 4 0 0 4 4 4 2 ATP-grasp domain Peptidase_C26 PF07722.13 ORX83309.1 - 0.00055 19.8 0.1 0.042 13.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.11 ORX83309.1 - 0.0069 16.0 0.1 0.64 9.6 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Cyclin_N PF00134.23 ORX83310.1 - 1.4e-10 41.0 0.6 4.8e-10 39.3 0.1 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.26 ORX83310.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme 7tm_2 PF00002.24 ORX83312.1 - 6e-05 22.5 8.2 6.9e-05 22.2 8.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 ORX83312.1 - 0.00018 20.7 6.8 0.00021 20.5 6.8 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Afaf PF15339.6 ORX83312.1 - 0.034 13.9 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2207 PF09972.9 ORX83312.1 - 3 6.5 4.8 3.6 6.2 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M16_C PF05193.21 ORX83393.1 - 2.4e-45 154.8 0.0 4.4e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORX83393.1 - 8.9e-45 152.3 0.0 2.6e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Lon_C PF05362.13 ORX83394.1 - 1.8e-69 233.4 0.0 3.7e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORX83394.1 - 8.5e-35 120.5 0.0 2.3e-34 119.1 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORX83394.1 - 1.3e-22 80.6 0.0 3.5e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 ORX83394.1 - 3.9e-07 29.9 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 ORX83394.1 - 5.8e-07 29.6 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORX83394.1 - 2.7e-06 27.6 0.0 6.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORX83394.1 - 5.4e-05 23.7 0.3 0.00083 19.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 ORX83394.1 - 9.1e-05 21.5 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ORX83394.1 - 0.00011 22.0 0.0 0.00043 20.1 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX83394.1 - 0.0003 21.1 0.1 0.0028 17.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX83394.1 - 0.0011 19.4 0.6 0.0075 16.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 ORX83394.1 - 0.005 16.8 0.5 0.23 11.4 0.0 3.1 2 1 1 3 3 3 1 NTPase AAA_14 PF13173.6 ORX83394.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORX83394.1 - 0.035 13.3 0.1 0.075 12.2 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 ORX83394.1 - 0.04 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 ORX83394.1 - 0.042 14.0 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase AAA_30 PF13604.6 ORX83394.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORX83394.1 - 0.052 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 ORX83394.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORX83394.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 ORX83394.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain TsaE PF02367.17 ORX83394.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PSK_trans_fac PF07704.11 ORX83394.1 - 0.14 13.0 0.3 39 5.1 0.0 3.1 2 0 0 2 2 2 0 Rv0623-like transcription factor TauD PF02668.16 ORX83395.1 - 7e-55 186.7 0.1 9e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CDC24_OB3 PF17244.2 ORX83396.1 - 1.4e-41 142.7 0.0 3e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 ORX83396.1 - 2e-24 86.6 0.0 3.8e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 ORX83396.1 - 2.1e-22 79.5 0.3 3.2e-22 78.9 0.3 1.3 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 Rep_fac-A_C PF08646.10 ORX83396.1 - 0.0067 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain FAA_hydrolase PF01557.18 ORX83397.1 - 1.2e-48 165.7 0.0 1.6e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RhoGEF PF00621.20 ORX83398.1 - 0.15 12.3 1.3 0.19 11.9 0.3 1.7 2 0 0 2 2 2 0 RhoGEF domain RhoGEF PF00621.20 ORX83399.1 - 8.8e-33 114.1 0.5 1.4e-32 113.4 0.5 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 ORX83399.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Ku_PK_bind PF08785.11 ORX83399.1 - 0.075 13.2 0.3 0.39 10.9 0.1 2.2 1 1 1 2 2 2 0 Ku C terminal domain like SPX PF03105.19 ORX83399.1 - 0.091 12.7 3.9 0.099 12.5 3.7 1.3 1 1 0 1 1 1 0 SPX domain Amido_AtzD_TrzD PF09663.10 ORX83399.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 1 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Piwi PF02171.17 ORX83400.1 - 5.6e-90 301.6 0.0 7.7e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORX83400.1 - 5.6e-17 62.6 0.0 9.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 ORX83400.1 - 1.3e-16 60.0 0.0 4.6e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 ORX83400.1 - 1.1e-15 57.7 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 ORX83400.1 - 3e-09 37.0 0.0 8.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 ORX83400.1 - 2.2e-08 34.3 0.0 6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain RAI1 PF08652.11 ORX83401.1 - 1.7e-27 95.4 0.1 3.7e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Phage_holin_3_3 PF16083.5 ORX83402.1 - 0.071 13.2 0.1 0.25 11.5 0.1 2.0 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Cation_efflux PF01545.21 ORX83403.1 - 4.4e-27 95.1 11.7 5.2e-27 94.9 11.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORX83403.1 - 4.6e-09 36.3 0.0 8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Thioredoxin_4 PF13462.6 ORX83404.1 - 4e-11 43.4 0.0 7.4e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ORX83404.1 - 0.0011 18.8 0.1 0.98 9.2 0.1 2.7 1 1 1 2 2 2 2 DSBA-like thioredoxin domain YcbB PF08664.10 ORX83404.1 - 0.093 12.8 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 YcbB domain SeqA PF03925.13 ORX83404.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 SeqA protein C-terminal domain zf-ZPR1 PF03367.13 ORX83407.1 - 4.8e-97 322.3 3.3 1.3e-50 171.4 0.2 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HTH_40 PF14493.6 ORX83407.1 - 0.098 13.1 0.3 0.79 10.2 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain CorC_HlyC PF03471.17 ORX83407.1 - 0.11 12.5 0.2 13 5.9 0.0 3.1 2 1 1 3 3 3 0 Transporter associated domain zf-RRPl_C4 PF17026.5 ORX83407.1 - 0.68 10.1 8.2 4.9 7.3 0.8 2.6 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Dabb PF07876.12 ORX83408.1 - 5.3e-16 59.0 0.0 5.6e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HAD PF12710.7 ORX83409.1 - 2.5e-10 41.1 0.0 3.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX83409.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX83409.1 - 0.11 12.6 0.0 0.55 10.3 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ORX83410.1 - 2e-74 250.3 0.0 2.5e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX83410.1 - 1.4e-33 116.3 0.0 1.9e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX83410.1 - 3.1e-10 39.9 0.0 5.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX83410.1 - 4.7e-06 25.6 1.0 0.00015 20.7 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 ORX83410.1 - 0.0017 18.3 0.0 0.0048 16.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX83410.1 - 0.0018 17.6 0.0 0.0043 16.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 ORX83410.1 - 0.0042 17.1 0.0 0.047 13.8 0.0 2.3 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Phage_CP76 PF06892.11 ORX83410.1 - 0.035 13.6 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) ABC1 PF03109.16 ORX83410.1 - 0.036 14.2 0.6 0.33 11.1 0.1 2.1 1 1 1 2 2 2 0 ABC1 family YrbL-PhoP_reg PF10707.9 ORX83410.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Plectin PF00681.20 ORX83410.1 - 0.18 11.7 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat RPAP1_C PF08620.10 ORX83411.1 - 3.1e-05 24.0 4.8 2.7 8.2 0.1 3.3 3 0 0 3 3 3 3 RPAP1-like, C-terminal DUF4781 PF16013.5 ORX83411.1 - 0.055 12.3 0.7 0.094 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) MG2 PF01835.19 ORX83411.1 - 0.074 13.5 0.0 23 5.5 0.0 3.0 3 0 0 3 3 3 0 MG2 domain DUF3679 PF12438.8 ORX83411.1 - 0.5 10.1 9.7 8.4 6.2 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3679) Methyltransf_33 PF10017.9 ORX83412.1 - 5.2e-55 186.8 0.0 5.8e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_7 PF03492.15 ORX83413.1 - 4.3e-26 91.9 0.1 6.4e-26 91.4 0.1 1.4 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Mg_trans_NIPA PF05653.14 ORX83453.1 - 8.7e-16 57.9 13.5 1.4e-09 37.5 6.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORX83453.1 - 0.05 13.8 26.2 0.52 10.5 6.8 2.8 2 1 0 2 2 2 0 EamA-like transporter family DUF2427 PF10348.9 ORX83453.1 - 3.8 7.3 9.0 0.58 10.0 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MS_channel PF00924.18 ORX83454.1 - 2e-25 89.6 2.4 4.7e-25 88.3 2.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2709 PF10915.8 ORX83454.1 - 0.0024 17.2 0.4 0.0048 16.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2709) JIP_LZII PF16471.5 ORX83454.1 - 0.019 15.1 0.2 0.019 15.1 0.2 2.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II FlgN PF05130.12 ORX83454.1 - 0.11 13.0 1.4 16 6.0 0.1 2.6 2 0 0 2 2 2 0 FlgN protein E1-E2_ATPase PF00122.20 ORX83454.1 - 4.8 6.7 8.1 1.4 8.4 0.8 2.4 2 0 0 2 2 2 0 E1-E2 ATPase RasGEF PF00617.19 ORX83455.1 - 6.2e-39 134.0 0.0 1.5e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Vps8 PF12816.7 ORX83455.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Cyclin PF08613.11 ORX83456.1 - 1.4e-08 35.3 0.9 1.8e-07 31.6 0.9 2.1 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX83456.1 - 0.0023 17.7 0.2 0.023 14.4 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain KxDL PF10241.9 ORX83458.1 - 2.4e-20 72.6 1.0 3.3e-20 72.1 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein BLOC1_2 PF10046.9 ORX83458.1 - 0.054 13.8 0.3 0.086 13.2 0.1 1.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4559 PF15112.6 ORX83458.1 - 0.055 13.1 2.6 0.063 13.0 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3010 PF11215.8 ORX83458.1 - 0.075 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) fn3_2 PF16893.5 ORX83459.1 - 1.3e-27 95.7 0.0 2.3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 ORX83459.1 - 1.6e-26 92.0 0.2 2.7e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 ORX83459.1 - 1e-16 60.6 0.0 1.7e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORX83459.1 - 7.7e-12 45.4 0.1 1.7e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 ORX83459.1 - 7.5e-07 29.3 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 ORX83459.1 - 0.002 18.4 0.0 0.0044 17.3 0.0 1.6 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 ORX83459.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain UBA PF00627.31 ORX83460.1 - 2.8e-08 33.5 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 ORX83460.1 - 0.036 13.9 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain HBS1_N PF08938.10 ORX83460.1 - 0.041 14.2 2.0 0.044 14.1 0.2 2.0 2 0 0 2 2 2 0 HBS1 N-terminus AP1AR PF15745.5 ORX83460.1 - 0.17 11.5 2.9 0.35 10.5 2.9 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF3472 PF11958.8 ORX83461.1 - 4.5e-06 27.2 0.3 9.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) SNF2_N PF00176.23 ORX83462.1 - 3.3e-11 42.5 0.0 4.1e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain VirB7 PF17413.2 ORX83462.1 - 0.079 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 Helicase_C PF00271.31 ORX83463.1 - 0.049 14.0 0.0 0.049 14.0 0.0 1.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain LPMO_10 PF03067.15 ORX83507.1 - 9.4e-07 29.7 0.0 1.2e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX83507.1 - 0.0031 17.5 0.1 0.19 11.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Aa_trans PF01490.18 ORX83508.1 - 5.6e-34 117.6 30.3 8.5e-34 116.9 30.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Polysacc_deac_1 PF01522.21 ORX83509.1 - 4e-34 117.2 0.1 6e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX83509.1 - 0.057 12.6 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 ORX83510.1 - 2.2e-34 118.0 0.2 6.8e-34 116.4 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Astro_capsid_p PF12226.8 ORX83510.1 - 0.0042 16.3 3.8 0.006 15.8 3.8 1.1 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Glyco_hydro_57 PF03065.15 ORX83510.1 - 0.056 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Arrestin_C PF02752.22 ORX83511.1 - 3.3e-13 50.2 0.5 3.9e-09 37.0 0.2 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX83511.1 - 1.9e-10 40.9 0.0 3.3e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX83511.1 - 1.8e-05 24.1 0.0 0.016 14.4 0.0 2.5 2 1 0 2 2 2 2 Rgp1 LDB19 PF13002.7 ORX83511.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_C PF02752.22 ORX83512.1 - 4.1e-14 53.2 0.9 3.1e-09 37.4 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX83512.1 - 3.8e-12 46.5 0.1 8.4e-11 42.1 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX83512.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 ORX83512.1 - 0.0014 17.9 0.7 0.69 9.0 0.1 2.8 2 1 0 3 3 3 2 Rgp1 ThiC_Rad_SAM PF01964.18 ORX83512.1 - 0.0067 15.3 0.1 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 Radical SAM ThiC family Cpn60_TCP1 PF00118.24 ORX83513.1 - 6.7e-162 539.5 1.9 7.5e-162 539.4 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 ORX83513.1 - 0.019 14.8 0.1 0.24 11.2 0.1 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein GFA PF04828.14 ORX83514.1 - 1.2e-09 38.4 0.2 1.2e-09 38.4 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Aldedh PF00171.22 ORX83515.1 - 1.4e-17 63.4 6.2 1.4e-15 56.8 4.0 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF3421 PF11901.8 ORX83516.1 - 2.1e-49 166.3 3.3 8.9e-13 48.2 0.0 5.0 1 1 4 5 5 5 5 Protein of unknown function (DUF3421) DRMBL PF07522.14 ORX83517.1 - 0.15 12.2 0.3 0.28 11.4 0.2 1.6 1 1 0 1 1 1 0 DNA repair metallo-beta-lactamase DUF4404 PF14357.6 ORX83517.1 - 0.22 12.2 3.2 0.52 11.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Exonuc_VII_L PF02601.15 ORX83517.1 - 0.68 9.5 3.4 0.81 9.2 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MutS_V PF00488.21 ORX83518.1 - 7.8e-35 120.6 0.2 1.6e-34 119.6 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORX83518.1 - 9.4e-12 45.6 0.3 3.2e-11 43.8 0.3 1.9 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 ORX83518.1 - 2.3e-05 24.6 0.8 6.9e-05 23.1 0.8 1.9 1 0 0 1 1 1 1 MutS family domain IV HNH PF01844.23 ORX83518.1 - 0.015 15.5 14.4 0.076 13.2 14.4 2.4 1 0 0 1 1 1 0 HNH endonuclease Mucin-like PF16058.5 ORX83518.1 - 0.045 13.8 30.9 0.095 12.8 30.9 1.5 1 0 0 1 1 1 0 Mucin-like DUF1963 PF09234.10 ORX83555.1 - 2.4e-12 47.8 0.0 3.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) YkyA PF10368.9 ORX83556.1 - 0.19 11.4 7.8 0.33 10.6 7.8 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Sec20 PF03908.13 ORX83556.1 - 0.2 11.6 1.5 1.4 8.9 0.2 2.4 1 1 1 2 2 2 0 Sec20 Vac_ImportDeg PF09783.9 ORX83557.1 - 5.3e-38 130.4 0.1 7.1e-38 130.0 0.1 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF2510 PF10708.9 ORX83557.1 - 0.55 10.0 2.5 17 5.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2510) zf-C2H2 PF00096.26 ORX83558.1 - 6e-17 61.1 19.5 1.9e-06 28.0 1.7 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX83558.1 - 2.1e-16 59.5 18.3 7.9e-08 32.4 2.8 3.5 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX83558.1 - 2.9e-13 49.4 16.3 0.00046 20.8 2.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX83558.1 - 3.6e-09 36.4 12.3 9.6e-05 22.3 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX83558.1 - 4.3e-06 26.9 6.1 0.022 15.0 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORX83558.1 - 8.9e-05 22.9 8.9 0.27 11.7 0.7 3.1 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 ORX83558.1 - 0.00014 21.9 2.7 3 8.0 0.0 3.2 2 1 1 3 3 3 2 Zic proteins zinc finger domain zf-met PF12874.7 ORX83558.1 - 0.0014 19.0 7.3 5.1 7.6 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 ORX83558.1 - 0.0016 18.0 3.8 0.93 9.1 0.2 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 ORX83558.1 - 0.0019 18.9 6.7 0.024 15.3 0.5 2.7 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 ORX83558.1 - 0.0022 18.3 2.1 0.0022 18.3 2.1 1.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX83558.1 - 0.0051 16.5 10.7 0.065 13.0 0.1 3.5 4 0 0 4 4 4 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 ORX83558.1 - 0.011 15.8 10.5 0.33 11.1 0.7 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.16 ORX83558.1 - 0.017 15.3 15.1 1.4 9.1 1.8 3.3 1 1 2 3 3 3 0 AN1-like Zinc finger C1_1 PF00130.22 ORX83558.1 - 0.034 14.0 3.7 1.2 9.0 0.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 ORX83558.1 - 0.037 13.9 2.7 0.037 13.9 2.7 3.2 3 1 0 3 3 3 0 zinc-finger of a C2HC-type CpXC PF14353.6 ORX83558.1 - 0.052 13.6 6.0 8.1 6.5 0.1 3.0 1 1 2 3 3 3 0 CpXC protein zinc_ribbon_15 PF17032.5 ORX83558.1 - 0.053 14.3 2.7 0.12 13.2 2.7 1.6 1 1 0 1 1 1 0 zinc-ribbon family zf-BED PF02892.15 ORX83558.1 - 0.064 13.3 8.5 0.26 11.3 1.6 2.8 1 1 2 3 3 3 0 BED zinc finger DUF2757 PF10955.8 ORX83558.1 - 0.18 12.1 3.8 5 7.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) zf-ZPR1 PF03367.13 ORX83558.1 - 0.23 11.3 1.5 0.82 9.5 1.2 1.9 1 1 1 2 2 2 0 ZPR1 zinc-finger domain HypA PF01155.19 ORX83558.1 - 0.23 11.5 3.1 0.17 11.9 1.4 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 ORX83558.1 - 0.35 10.9 9.6 3 7.9 0.3 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DZR PF12773.7 ORX83558.1 - 0.5 10.4 6.3 1.9 8.6 6.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 ORX83558.1 - 0.53 9.8 5.3 3.5 7.2 0.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORX83558.1 - 0.55 10.2 5.2 3.3 7.8 5.2 2.4 1 1 0 1 1 1 0 zinc-ribbons LIM PF00412.22 ORX83558.1 - 0.99 9.7 7.9 1 9.6 5.0 2.3 1 1 1 2 2 2 0 LIM domain zinc_ribbon_4 PF13717.6 ORX83558.1 - 1 9.3 7.6 6.5 6.8 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain RNHCP PF12647.7 ORX83558.1 - 1.6 8.7 8.7 0.66 10.0 0.8 2.6 2 1 0 3 3 3 0 RNHCP domain zf-LYAR PF08790.11 ORX83558.1 - 2.2 8.2 10.9 29 4.7 2.0 3.6 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 ORX83558.1 - 3.2 8.1 10.7 1.4 9.2 4.4 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain DUF983 PF06170.12 ORX83558.1 - 5 7.6 4.6 8.3 6.9 0.1 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF983) XPA_N PF01286.18 ORX83558.1 - 6.3 6.9 13.3 2.1 8.5 0.4 3.4 4 0 0 4 4 3 0 XPA protein N-terminal Adenylsucc_synt PF00709.21 ORX83559.1 - 1.8e-183 610.3 0.0 2e-183 610.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase GAF PF01590.26 ORX83559.1 - 0.01 16.5 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain KHA PF11834.8 ORX83559.1 - 0.051 13.7 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel CBM_19 PF03427.13 ORX83561.1 - 0.12 12.3 34.2 0.1 12.6 4.4 4.9 5 0 0 5 5 5 0 Carbohydrate binding domain (family 19) zf-C2H2 PF00096.26 ORX83603.1 - 3.3e-20 71.3 25.2 3.1e-05 24.2 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX83603.1 - 3.4e-18 65.2 25.0 4.4e-06 26.9 1.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX83603.1 - 6.4e-10 39.0 23.6 0.01 16.6 0.7 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX83603.1 - 2.3e-05 24.9 8.5 0.33 11.6 0.1 3.6 3 1 1 4 4 4 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX83603.1 - 0.00047 20.4 7.9 0.078 13.3 6.3 2.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORX83603.1 - 0.002 18.4 6.9 1.4 9.3 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX83603.1 - 0.15 12.5 9.5 2.7 8.5 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORX83603.1 - 0.27 11.9 12.0 0.16 12.7 1.6 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORX83603.1 - 0.67 10.1 9.3 4.1 7.5 3.8 2.7 2 2 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 ORX83603.1 - 5.9 6.8 13.0 2.2 8.1 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type GATA PF00320.27 ORX83604.1 - 7.5e-16 57.4 7.3 1.5e-15 56.5 7.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORX83604.1 - 8.6e-12 45.2 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORX83604.1 - 3.9e-09 36.5 0.0 6.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORX83604.1 - 7.9e-07 29.3 0.0 4.2e-06 27.0 0.0 2.0 1 1 1 2 2 2 1 PAS domain PAS_11 PF14598.6 ORX83604.1 - 5.3e-05 23.3 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX83604.1 - 0.057 13.7 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 PAS fold Zn-ribbon_8 PF09723.10 ORX83604.1 - 0.066 13.3 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Glyco_hydro_72 PF03198.14 ORX83639.1 - 4.4e-129 430.3 6.5 5.8e-129 429.9 6.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORX83639.1 - 9e-22 77.6 3.4 2.3e-21 76.3 3.4 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 ORX83639.1 - 0.00082 18.9 0.1 0.11 11.9 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 ORX83639.1 - 0.0089 15.2 0.1 0.017 14.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain NIR_SIR PF01077.22 ORX83640.1 - 1.6e-53 180.5 0.0 1.1e-46 158.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ORX83640.1 - 5.5e-32 109.4 0.1 7.3e-16 57.8 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 ORX83640.1 - 1.7e-24 86.6 0.0 3.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 ORX83640.1 - 3.4e-22 79.3 0.1 1.5e-21 77.2 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 ORX83640.1 - 5.8e-07 29.8 0.0 1.9e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 ORX83640.1 - 0.025 14.5 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain Ribosomal_S4e PF00900.20 ORX83641.1 - 9.2e-36 121.6 0.1 2e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX83641.1 - 9.4e-27 92.4 0.1 1.6e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORX83641.1 - 2.8e-21 75.3 6.6 6.5e-21 74.2 6.6 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORX83641.1 - 1.4e-08 34.3 0.1 3.3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORX83641.1 - 5.2e-05 23.0 9.0 7.2e-05 22.6 4.4 3.1 3 0 0 3 3 3 1 KOW motif SRP54 PF00448.22 ORX83642.1 - 5.6e-78 261.1 0.4 1.2e-77 260.0 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ORX83642.1 - 7.9e-32 109.8 1.0 7.9e-32 109.8 1.0 4.5 3 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.19 ORX83642.1 - 7.5e-20 70.9 2.2 2.2e-19 69.4 2.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 ORX83642.1 - 6.4e-06 25.9 0.2 2.1e-05 24.2 0.1 1.9 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORX83642.1 - 4.5e-05 22.6 0.5 0.0036 16.3 0.1 3.1 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 ORX83642.1 - 6.3e-05 22.5 0.8 0.21 11.0 0.1 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit ResIII PF04851.15 ORX83642.1 - 9.4e-05 22.5 0.5 0.00023 21.2 0.5 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 ORX83642.1 - 0.00022 21.4 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORX83642.1 - 0.00029 21.3 0.4 0.0022 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX83642.1 - 0.00042 20.7 0.0 0.00099 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 ORX83642.1 - 0.00069 19.7 0.0 0.0021 18.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 ORX83642.1 - 0.005 17.1 0.0 0.023 14.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 ORX83642.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase MobB PF03205.14 ORX83642.1 - 0.0096 15.8 0.6 0.051 13.5 0.1 2.3 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 ORX83642.1 - 0.0096 16.4 1.5 0.084 13.3 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORX83642.1 - 0.012 15.4 0.1 0.035 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 ORX83642.1 - 0.013 16.0 0.0 0.041 14.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ORX83642.1 - 0.014 15.2 0.3 0.05 13.4 0.1 2.1 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ORX83642.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 ORX83642.1 - 0.019 14.9 0.1 0.058 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORX83642.1 - 0.025 14.7 0.2 0.13 12.3 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase CLP1_P PF16575.5 ORX83642.1 - 0.061 13.1 0.2 8.8 6.1 0.0 2.7 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 ORX83642.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DNA_pol3_chi PF04364.13 ORX83642.1 - 0.098 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Thymidylate_kin PF02223.17 ORX83642.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase Paramyxo_P PF01806.17 ORX83642.1 - 0.11 12.0 0.1 0.84 9.0 0.1 2.2 1 1 1 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region AAA_25 PF13481.6 ORX83642.1 - 0.19 11.3 0.2 0.78 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 ORX83642.1 - 0.53 9.4 7.7 0.33 10.1 0.1 3.2 2 2 0 2 2 2 0 Anion-transporting ATPase Ribosomal_S18 PF01084.20 ORX83643.1 - 5.5e-21 74.5 0.1 1.2e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Septin PF00735.18 ORX83644.1 - 9.5e-117 389.3 0.1 9.5e-117 389.3 0.1 2.1 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORX83644.1 - 1e-06 28.8 0.4 4.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX83644.1 - 7.2e-06 25.7 5.6 0.00031 20.3 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX83644.1 - 6.2e-05 23.0 0.2 6.2e-05 23.0 0.2 3.3 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 ORX83644.1 - 0.0061 15.9 1.4 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 ORX83644.1 - 0.01 15.5 0.3 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 ORX83644.1 - 0.012 15.8 0.3 0.03 14.5 0.0 1.8 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORX83644.1 - 0.028 14.7 1.0 0.09 13.1 0.1 2.5 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 ORX83644.1 - 0.03 14.8 4.7 0.053 14.0 0.1 2.5 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 ORX83644.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORX83644.1 - 0.036 14.1 10.1 0.23 11.5 0.1 3.6 3 1 0 3 3 2 0 Dynamin family DUF1719 PF08224.11 ORX83644.1 - 0.043 12.9 0.2 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1719) AAA_24 PF13479.6 ORX83644.1 - 0.043 13.5 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX83644.1 - 0.057 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Atg14 PF10186.9 ORX83644.1 - 0.066 12.3 8.9 0.11 11.6 8.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myb_DNA-bind_3 PF12776.7 ORX83644.1 - 0.071 14.1 2.6 14 6.8 2.8 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Exonuc_VII_L PF02601.15 ORX83644.1 - 0.11 12.1 7.4 0.18 11.3 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FtsK_SpoIIIE PF01580.18 ORX83644.1 - 0.26 10.6 2.4 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family OmpH PF03938.14 ORX83644.1 - 0.49 10.7 10.7 1.4 9.3 10.7 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Caldesmon PF02029.15 ORX83644.1 - 0.57 8.9 17.6 0.23 10.2 15.6 1.3 2 0 0 2 2 2 0 Caldesmon DUF87 PF01935.17 ORX83644.1 - 0.82 9.7 0.0 0.82 9.7 0.0 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain SWI-SNF_Ssr4 PF08549.10 ORX83644.1 - 1.5 7.3 10.7 2.4 6.7 10.7 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ATP_bind_1 PF03029.17 ORX83644.1 - 1.9 8.2 7.2 17 5.1 0.0 3.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein TMPIT PF07851.13 ORX83644.1 - 2.8 7.1 6.5 4.5 6.4 6.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.13 ORX83644.1 - 7.2 7.3 7.7 8.5 7.1 6.2 1.9 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) PAS PF00989.25 ORX83645.1 - 0.00021 21.2 0.0 0.00049 20.1 0.0 1.6 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 ORX83645.1 - 0.0012 18.9 11.8 0.0012 18.9 11.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_27 PF13463.6 ORX83645.1 - 0.08 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Fasciclin PF02469.22 ORX83646.1 - 2e-46 157.4 0.0 6e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Zip PF02535.22 ORX83647.1 - 3.1e-22 79.3 0.0 3.7e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TssN PF17555.2 ORX83647.1 - 0.81 9.0 4.9 1.1 8.6 4.9 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN CPP1-like PF11833.8 ORX83647.1 - 4.2 7.0 8.1 23 4.6 5.8 2.5 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LIM_bind PF01803.16 ORX83648.1 - 5.1e-58 196.5 0.6 5.1e-58 196.5 0.6 2.1 3 1 0 3 3 3 1 LIM-domain binding protein Totivirus_coat PF05518.11 ORX83648.1 - 5.6 4.9 8.5 7.8 4.4 8.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein Velvet PF11754.8 ORX83649.1 - 2.6e-57 194.7 0.4 4.4e-37 128.4 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Cyclin_N PF00134.23 ORX83753.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX83753.1 - 0.042 14.2 0.3 0.076 13.4 0.1 1.6 1 1 1 2 2 2 0 Cyclin Hexokinase_2 PF03727.16 ORX83754.1 - 4.7e-72 242.3 0.0 6.4e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX83754.1 - 2.5e-64 216.9 0.0 3.4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase zf-CCCH PF00642.24 ORX83755.1 - 6.4e-15 54.6 16.7 4.6e-10 39.2 3.0 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX83755.1 - 5.8e-08 32.4 14.3 6.1e-05 22.7 1.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX83755.1 - 9.1e-07 28.7 11.5 0.00056 19.9 2.7 2.7 2 1 0 2 2 2 2 Zinc finger domain CLIP_SPH_mas PF18398.1 ORX83755.1 - 0.0053 17.1 0.8 0.0053 17.1 0.8 2.1 2 0 0 2 2 2 1 Clip-domain serine protease homolog masquerade zf-CCCH_2 PF14608.6 ORX83755.1 - 0.0058 17.1 0.3 0.0058 17.1 0.3 2.7 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORX83755.1 - 0.14 12.9 12.3 0.2 12.4 3.9 2.0 1 1 1 2 2 2 0 Torus domain zf-CCHH PF10283.9 ORX83755.1 - 4.3 7.4 11.8 5 7.2 0.3 3.0 3 0 0 3 3 3 0 PBZ domain MFS_1 PF07690.16 ORX83756.1 - 3.4e-22 78.9 44.8 5e-17 61.9 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2545 PF10810.8 ORX83756.1 - 0.043 13.9 4.9 0.34 11.1 0.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) Patched PF02460.18 ORX83756.1 - 2.1 6.3 9.4 0.77 7.8 2.7 2.1 2 0 0 2 2 2 0 Patched family Thiolase_N PF00108.23 ORX83757.1 - 5.3e-83 278.3 6.1 5.3e-83 278.3 6.1 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORX83757.1 - 2e-46 156.7 0.5 5.1e-46 155.3 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORX83757.1 - 0.011 15.4 3.3 0.017 14.7 0.2 2.5 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORX83757.1 - 0.034 14.0 0.3 12 5.9 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2180 PF09947.9 ORX83757.1 - 0.16 12.0 0.7 0.37 10.8 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Methyltransf_25 PF13649.6 ORX83759.1 - 0.012 16.3 0.0 5.4 7.8 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 ORX83759.1 - 0.028 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 ORX83759.1 - 0.18 11.1 0.0 0.63 9.3 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Cyclin_N PF00134.23 ORX83760.1 - 2.2e-11 43.6 0.0 2.6e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX83760.1 - 1.4e-08 35.2 0.1 2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin Spermine_synth PF01564.17 ORX83761.1 - 2.5e-70 235.7 0.0 1.3e-69 233.4 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORX83761.1 - 1.4e-23 82.5 0.1 2.4e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ORX83761.1 - 5.9e-05 23.7 0.0 0.00012 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX83761.1 - 0.0065 17.2 0.0 0.016 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORX83761.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 ORX83761.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_2 PF00891.18 ORX83761.1 - 0.044 13.1 0.1 0.12 11.7 0.1 1.8 1 1 1 2 2 2 0 O-methyltransferase domain Glyco_tranf_2_5 PF13712.6 ORX83761.1 - 0.13 11.9 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family zf-C2H2 PF00096.26 ORX83762.1 - 4.8e-13 48.8 9.9 1.2e-06 28.7 2.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX83762.1 - 5.7e-10 39.2 15.4 2.4e-07 30.9 0.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX83762.1 - 1.5e-09 37.9 8.0 5.3e-05 23.7 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX83762.1 - 1.5e-06 28.1 6.6 4.8e-05 23.2 0.9 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX83762.1 - 0.00011 21.9 2.6 0.039 13.7 0.4 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORX83762.1 - 0.00042 20.5 3.2 0.00096 19.4 0.8 2.4 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX83762.1 - 0.00056 20.2 4.2 0.0036 17.6 0.8 2.9 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX83762.1 - 0.0029 17.9 0.9 0.0076 16.5 0.1 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 ORX83762.1 - 0.015 15.4 1.3 3.2 8.0 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-DNA_Pol PF08996.10 ORX83762.1 - 0.023 14.5 0.3 0.024 14.4 0.3 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 ORX83762.1 - 0.1 12.7 2.8 0.88 9.6 2.8 2.1 1 1 0 1 1 1 0 BED zinc finger Zn_ribbon_SprT PF17283.2 ORX83762.1 - 0.13 12.1 7.5 0.17 11.8 2.2 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 ORX83762.1 - 0.42 10.6 0.2 0.42 10.6 0.2 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.7 ORX83762.1 - 0.73 9.9 5.8 1.8 8.6 5.8 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 ORX83762.1 - 0.84 10.1 4.5 1.5 9.4 0.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Nkap_C PF06047.11 ORX83853.1 - 1.9e-49 166.0 2.2 1.9e-49 166.0 2.2 1.9 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain PPL5 PF18168.1 ORX83853.1 - 0.69 9.2 6.0 0.2 10.9 2.4 1.8 2 0 0 2 2 2 0 Prim-pol family 5 Bromodomain PF00439.25 ORX83855.1 - 1.3e-49 166.2 3.8 7.6e-24 83.6 0.9 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 ORX83855.1 - 1e-21 76.9 1.3 1.9e-21 76.0 1.3 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SlyX PF04102.12 ORX83855.1 - 0.079 13.6 0.9 0.29 11.8 0.9 2.0 1 0 0 1 1 1 0 SlyX V_ATPase_I PF01496.19 ORX83855.1 - 0.16 9.8 1.7 0.28 9.0 1.7 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3292 PF11696.8 ORX83855.1 - 5.5 5.2 10.3 9.2 4.5 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) YqzE PF14038.6 ORX83855.1 - 7.1 6.7 8.4 0.54 10.3 2.0 2.4 2 0 0 2 2 2 0 YqzE-like protein SRP-alpha_N PF04086.13 ORX83855.1 - 8.8 6.2 22.2 1.6 8.6 8.0 3.0 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal TRAPP PF04051.16 ORX83856.1 - 3.8e-46 156.4 0.0 4.4e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.21 ORX83857.1 - 1.5e-58 198.3 0.0 3.6e-58 197.1 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ORX83857.1 - 0.00097 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DHHC PF01529.20 ORX83858.1 - 6.1e-36 123.5 7.8 6.1e-36 123.5 7.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 ORX83858.1 - 0.61 10.2 3.9 31 4.8 4.1 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF2975 PF11188.8 ORX83858.1 - 1.2 9.0 4.6 1.2 9.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) PAC2 PF09754.9 ORX83859.1 - 9.4e-26 91.1 0.0 1.2e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family UCH PF00443.29 ORX83860.1 - 5.6e-33 114.5 0.0 7.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX83860.1 - 0.00033 20.4 1.8 0.00077 19.1 1.8 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORX83860.1 - 0.015 14.7 5.4 0.12 11.8 0.0 3.6 2 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase VDE PF07137.11 ORX83861.1 - 0.038 13.5 7.8 0.051 13.1 7.8 1.1 1 0 0 1 1 1 0 VDE lipocalin domain PAN_3 PF08277.12 ORX83861.1 - 2.4 8.0 13.0 1.9 8.4 1.7 2.9 1 1 2 3 3 3 0 PAN-like domain DUF4718 PF15842.5 ORX83861.1 - 4.8 6.9 8.1 0.29 10.9 3.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) zf-C2H2 PF00096.26 ORX83862.1 - 7.8e-15 54.4 12.0 4.2e-08 33.2 3.3 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX83862.1 - 1.3e-10 41.2 9.3 2e-05 25.0 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX83862.1 - 3e-10 40.1 16.3 3.4e-08 33.6 2.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX83862.1 - 0.00016 21.9 1.1 0.072 13.4 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX83862.1 - 0.00019 22.1 1.2 0.00021 21.9 1.2 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_6 PF13912.6 ORX83862.1 - 0.00098 19.1 5.1 0.46 10.6 1.4 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORX83862.1 - 0.0022 18.6 0.4 0.083 13.5 0.0 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-met PF12874.7 ORX83862.1 - 0.015 15.7 1.3 2 8.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX83862.1 - 0.061 13.2 1.8 2.1 8.3 0.1 2.4 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 ORX83862.1 - 0.066 13.0 7.8 0.31 10.8 2.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 ORX83862.1 - 0.089 12.6 0.2 7.8 6.4 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 ORX83862.1 - 0.15 11.7 1.1 0.75 9.5 0.3 1.9 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 ORX83862.1 - 0.17 11.7 4.8 3.6 7.5 1.7 2.0 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.7 ORX83862.1 - 0.2 12.0 2.0 0.77 10.1 0.2 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) F-box-like PF12937.7 ORX83863.1 - 9.4e-14 51.0 0.9 1.8e-13 50.1 0.8 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORX83863.1 - 2.2e-07 30.6 0.7 4.4e-07 29.6 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORX83863.1 - 0.0034 17.3 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 F-box Sod_Cu PF00080.20 ORX83864.1 - 6.3e-47 159.3 5.9 7.4e-47 159.1 5.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Erv26 PF04148.13 ORX83865.1 - 1e-60 205.1 12.5 6.8e-60 202.4 12.5 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DsbD PF02683.15 ORX83865.1 - 0.0035 17.3 5.3 0.0046 16.9 5.2 1.3 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF4018 PF13210.6 ORX83865.1 - 0.034 13.9 1.1 0.034 13.9 1.1 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4018) Kelch_3 PF13415.6 ORX83866.1 - 1.9e-39 133.2 4.1 4.1e-10 39.7 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 ORX83866.1 - 1.9e-35 120.6 7.6 5.5e-10 39.1 0.1 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX83866.1 - 5.7e-26 89.9 8.6 6.5e-06 26.2 0.0 6.7 5 2 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ORX83866.1 - 1.1e-23 82.7 9.8 6.2e-05 22.9 0.1 6.5 6 1 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 ORX83866.1 - 5.7e-18 64.8 12.8 5.7e-18 64.8 12.8 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 ORX83866.1 - 1.7e-13 50.0 11.5 0.0041 17.0 0.2 6.9 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORX83866.1 - 7.2e-13 47.9 13.6 0.003 17.1 0.1 6.9 6 1 0 6 6 6 4 Kelch motif Alginate_lyase PF05426.12 ORX83867.1 - 2.5e-70 237.2 0.0 2.7e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase HSF_DNA-bind PF00447.17 ORX83906.1 - 1.5e-25 89.6 0.8 1.6e-25 89.5 0.8 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Oxidored_molyb PF00174.19 ORX83907.1 - 3.2e-57 192.9 0.0 5.1e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORX83907.1 - 7.5e-40 136.1 0.4 2.8e-39 134.3 0.1 2.1 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 ORX83907.1 - 1.2e-28 99.3 0.0 2.7e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORX83907.1 - 8.1e-28 97.3 0.0 1.5e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORX83907.1 - 2e-22 79.1 0.0 4.4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORX83907.1 - 3.6e-08 33.7 0.0 2.4e-06 27.8 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF3336 PF11815.8 ORX83908.1 - 4.5e-16 58.8 0.0 8.8e-15 54.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORX83908.1 - 3.2e-14 53.6 0.0 5.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Pro_isomerase PF00160.21 ORX83909.1 - 9.3e-51 172.2 0.0 3e-50 170.5 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORX83909.1 - 3.9e-08 33.8 0.5 0.0061 17.4 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2491 PF10679.9 ORX83909.1 - 0.033 13.4 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Abhydrolase_6 PF12697.7 ORX83910.1 - 4e-14 53.7 0.0 6.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX83910.1 - 0.0001 22.1 0.2 0.046 13.4 0.1 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ORX83910.1 - 0.0004 20.2 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX83910.1 - 0.0029 16.9 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORX83910.1 - 0.0087 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 ORX83910.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 ORX83910.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 ORX83910.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 ORX83910.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORX83910.1 - 0.15 10.9 0.1 0.33 9.8 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme CHD5 PF04420.14 ORX83911.1 - 3.1e-43 147.4 1.5 4.2e-43 147.0 1.5 1.2 1 0 0 1 1 1 1 CHD5-like protein DUF3810 PF12725.7 ORX83911.1 - 0.0012 18.2 1.0 0.0012 18.2 1.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3810) CTP_transf_1 PF01148.20 ORX83912.1 - 2.3e-85 286.6 20.2 2.8e-85 286.3 20.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family MLTD_N PF06474.12 ORX83912.1 - 0.12 12.6 0.8 0.34 11.1 0.8 1.8 1 0 0 1 1 1 0 MltD lipid attachment motif Peptidase_S8 PF00082.22 ORX83913.1 - 6.6e-30 104.4 19.2 1.8e-29 102.9 19.2 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX83913.1 - 0.00074 20.1 0.1 0.0029 18.2 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 AMP-binding PF00501.28 ORX83914.1 - 1.5e-35 122.6 0.0 2.4e-34 118.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORX83914.1 - 6.3e-35 120.6 0.0 2.3e-34 118.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORX83914.1 - 1.7e-20 73.1 0.5 2.8e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 ORX83914.1 - 3.4e-06 26.7 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORX83915.1 - 4e-39 134.3 0.0 6.3e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORX83915.1 - 7.5e-22 77.5 0.5 4.8e-12 46.1 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.28 ORX83915.1 - 4.8e-11 41.9 1.0 9.4e-05 21.2 0.0 3.2 1 1 2 3 3 3 3 AMP-binding enzyme Epimerase PF01370.21 ORX83915.1 - 8.7e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Chitin_synth_2 PF03142.15 ORX83916.1 - 7.7e-12 44.6 3.8 1.3e-10 40.6 2.1 2.9 2 1 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX83916.1 - 3e-10 40.4 0.6 1.6e-08 34.8 0.6 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX83916.1 - 3.9e-07 30.2 4.4 3.9e-07 30.2 4.4 3.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX83916.1 - 5.6e-05 22.7 0.1 0.00014 21.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Wzy_C PF04932.15 ORX83916.1 - 0.00014 21.6 6.3 0.013 15.1 0.2 3.3 2 1 1 3 3 3 2 O-Antigen ligase Glycos_transf_2 PF00535.26 ORX83916.1 - 0.00017 21.4 0.0 0.097 12.5 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferase family 2 ChaB PF06150.12 ORX83916.1 - 0.067 13.8 0.0 0.24 12.0 0.0 2.0 1 0 0 1 1 1 0 ChaB DUF1772 PF08592.11 ORX83916.1 - 0.48 10.7 6.1 0.22 11.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3446 PF11928.8 ORX83917.1 - 0.011 16.0 1.2 0.014 15.6 1.2 1.1 1 0 0 1 1 1 0 Early growth response N-terminal domain Fungal_TACC PF12709.7 ORX83953.1 - 8.2e-05 23.0 8.0 0.0094 16.4 2.8 2.6 2 0 0 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins HALZ PF02183.18 ORX83953.1 - 0.0058 16.8 9.3 0.11 12.7 0.4 2.9 3 0 0 3 3 2 2 Homeobox associated leucine zipper APC_N_CC PF16689.5 ORX83953.1 - 0.02 15.0 3.3 0.02 15.0 3.3 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain HAUS5 PF14817.6 ORX83953.1 - 0.024 13.4 9.4 0.037 12.8 9.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1664 PF07889.12 ORX83953.1 - 0.14 12.2 2.8 0.23 11.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 ORX83953.1 - 0.15 12.1 11.5 0.27 11.3 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SOGA PF11365.8 ORX83953.1 - 0.34 12.1 7.3 8.2 7.6 0.7 2.9 1 1 1 2 2 2 0 Protein SOGA UPF0449 PF15136.6 ORX83953.1 - 0.41 11.2 10.9 0.083 13.4 6.7 2.2 2 1 0 2 2 1 0 Uncharacterised protein family UPF0449 Lzipper-MIP1 PF14389.6 ORX83953.1 - 0.55 10.6 10.5 0.65 10.3 7.5 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 ORX83953.1 - 0.69 9.7 11.2 0.85 9.4 2.6 2.4 1 1 1 2 2 2 0 Septum formation initiator betaPIX_CC PF16523.5 ORX83953.1 - 0.72 9.7 5.0 0.21 11.5 0.8 2.1 2 0 0 2 2 2 0 betaPIX coiled coil DUF5595 PF18077.1 ORX83953.1 - 1.1 9.4 8.5 3.4 7.8 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) ADIP PF11559.8 ORX83953.1 - 2 8.5 14.6 2.7 8.0 1.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 ORX83953.1 - 2.2 8.7 5.7 3 8.3 0.6 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) KIAA1430 PF13879.6 ORX83953.1 - 7.3 7.4 11.5 32 5.4 11.5 2.2 1 1 0 1 1 1 0 KIAA1430 homologue DMPK_coil PF08826.10 ORX83953.1 - 8.5 6.6 13.0 0.12 12.5 1.7 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like Arrestin_N PF00339.29 ORX83954.1 - 3.1e-10 40.3 0.0 6.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 ORX83954.1 - 0.00019 20.5 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 ORX83954.1 - 0.0015 19.0 1.3 0.0026 18.2 0.5 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX83954.1 - 0.019 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like DUF4203 PF13886.6 ORX83955.1 - 8.8e-31 107.1 24.3 9.8e-31 107.0 24.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mito_carr PF00153.27 ORX83956.1 - 3.7e-28 97.3 2.0 2.5e-15 56.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 ORX83957.1 - 2e-14 53.1 18.5 4e-05 23.8 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX83957.1 - 3.2e-13 49.4 11.0 1.2e-06 28.7 2.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX83957.1 - 1.1e-10 41.4 18.0 7.6e-05 23.2 1.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX83957.1 - 0.00029 20.5 10.9 0.038 13.8 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 ORX83957.1 - 0.0013 19.5 4.3 0.68 10.6 0.1 2.9 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORX83957.1 - 0.011 16.1 5.5 0.39 11.2 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORX83957.1 - 0.023 14.5 3.1 0.023 14.5 3.1 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORX83957.1 - 1 9.5 16.0 2.9 8.0 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-AN1 PF01428.16 ORX83957.1 - 2.4 8.4 9.3 4.5 7.5 0.5 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zf-BED PF02892.15 ORX83957.1 - 3 8.0 10.6 4.7 7.3 3.2 3.1 3 0 0 3 3 3 0 BED zinc finger DUF4764 PF15961.5 ORX83957.1 - 3.1 6.4 9.0 1.3 7.6 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) zf-C2H2_8 PF15909.5 ORX83957.1 - 3.8 7.9 8.4 5.9 7.3 4.8 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 ORX83957.1 - 8.4 6.9 13.3 1.2 9.6 2.3 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORX83957.1 - 9.9 6.6 8.5 20 5.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RICTOR_N PF14664.6 ORX83958.1 - 2.9e-83 279.9 4.0 7.7e-83 278.5 0.8 2.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 ORX83958.1 - 6.2e-43 145.6 1.1 7.6e-39 132.5 0.2 3.4 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 ORX83958.1 - 6.7e-39 131.9 1.9 6.9e-34 115.7 0.1 6.5 5 1 2 7 7 7 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 ORX83958.1 - 6.4e-31 106.4 0.2 1.6e-29 101.9 0.1 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 ORX83958.1 - 4.1e-09 36.2 4.0 0.6 10.2 0.0 5.8 4 1 1 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORX83958.1 - 0.0012 19.2 0.2 11 6.5 0.0 3.9 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 ORX83958.1 - 0.005 17.0 1.4 8.6 6.9 0.1 4.9 5 0 0 5 5 5 1 HEAT repeat Siva PF05458.12 ORX83959.1 - 9.2e-06 25.4 19.7 6e-05 22.8 18.6 2.0 1 1 1 2 2 2 2 Cd27 binding protein (Siva) MFS_1 PF07690.16 ORX83960.1 - 2.2e-09 36.7 3.4 2.3e-09 36.7 3.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX83960.1 - 7.7e-09 34.9 1.9 8.9e-09 34.7 1.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.19 ORX83960.1 - 5.9e-05 22.0 0.6 6.3e-05 21.9 0.6 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.7 ORX83960.1 - 0.0016 17.3 0.4 0.0017 17.3 0.4 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_5 PF05631.14 ORX83960.1 - 0.0051 15.8 0.1 0.0055 15.7 0.1 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 ORX83960.1 - 0.017 13.5 0.2 0.018 13.5 0.2 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Pkinase PF00069.25 ORX83994.1 - 8.9e-62 208.8 0.0 1e-42 146.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX83994.1 - 2.2e-24 86.1 0.0 5.1e-24 85.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX83994.1 - 1.8e-06 27.5 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX83994.1 - 0.00019 20.8 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX83994.1 - 0.00078 19.4 0.0 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX83994.1 - 0.0017 17.4 0.2 0.01 14.8 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX83994.1 - 0.014 14.5 0.2 0.023 13.8 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 ORX83994.1 - 0.037 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 ORX83994.1 - 0.067 12.8 0.5 0.11 12.0 0.5 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ubiquitin PF00240.23 ORX83995.1 - 2.3e-34 117.0 0.5 3.1e-34 116.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX83995.1 - 2.2e-16 59.5 0.4 3.4e-16 58.8 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 ORX83995.1 - 1.9e-13 50.4 1.2 1.9e-13 50.4 1.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 ORX83995.1 - 7.2e-06 26.4 0.1 2.8e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORX83995.1 - 0.0088 16.1 0.0 0.019 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Transp_Tc5_C PF04236.15 ORX83995.1 - 0.01 16.1 2.2 0.01 16.1 2.2 1.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain TBK1_ULD PF18396.1 ORX83995.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORX83995.1 - 0.019 15.3 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 ORX83995.1 - 0.049 13.7 0.6 4.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 ORX83995.1 - 0.051 14.1 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain FYVE PF01363.21 ORX83995.1 - 1.1 9.5 8.4 1.7 8.8 8.4 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.6 ORX83995.1 - 2.3 8.2 6.9 7.3 6.6 6.9 1.9 1 1 0 1 1 1 0 zinc-finger of a C2HC-type Ras PF00071.22 ORX83996.1 - 1.1e-52 177.9 0.1 1.3e-52 177.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX83996.1 - 7.6e-32 110.1 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX83996.1 - 5.7e-13 48.7 0.0 6.6e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX83996.1 - 3.7e-06 26.5 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX83996.1 - 3.9e-06 26.5 0.1 6.7e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX83996.1 - 5.7e-06 26.4 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX83996.1 - 0.004 17.1 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORX83996.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 ORX83996.1 - 0.04 13.7 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 ORX83996.1 - 0.061 12.5 0.1 1.1 8.4 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 ORX83996.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORX83996.1 - 0.098 12.9 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX83996.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NTPase cobW PF02492.19 ORX83996.1 - 0.14 11.7 0.0 1.2 8.6 0.0 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UreD PF01774.17 ORX83998.1 - 2.4e-51 174.7 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein HTH_55 PF18622.1 ORX83998.1 - 0.099 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 RctB helix turn helix domain SMI1_KNR4 PF09346.10 ORX84000.1 - 3.8e-06 27.3 0.3 8.5e-06 26.2 0.0 1.8 2 1 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORX84000.1 - 9e-05 22.9 0.1 0.00029 21.2 0.0 2.0 2 1 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 ORX84000.1 - 0.011 15.5 0.4 0.024 14.3 0.0 1.8 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Sec1 PF00995.23 ORX84001.1 - 8e-129 431.5 3.4 9e-129 431.3 3.4 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.25 ORX84002.1 - 5.2e-71 239.1 0.0 6.4e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX84002.1 - 2.8e-45 154.6 0.0 3.6e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX84002.1 - 9.4e-07 28.4 0.0 2.2e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORX84002.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORX84002.1 - 0.042 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORX84002.1 - 0.088 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORX84002.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORX84002.1 - 0.12 12.0 0.3 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GalKase_gal_bdg PF10509.9 ORX84003.1 - 3.1e-22 77.9 0.1 6.2e-22 76.9 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 ORX84003.1 - 1.1e-12 48.0 0.6 2.2e-12 47.0 0.6 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX84003.1 - 1.2e-12 48.1 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal zf-AN1 PF01428.16 ORX84004.1 - 5.1e-21 74.5 24.0 4.9e-12 45.8 4.4 3.0 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX84004.1 - 0.00068 20.0 16.0 0.017 15.4 3.7 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Syntaxin_2 PF14523.6 ORX84005.1 - 1.6e-27 95.8 8.6 3.3e-24 85.2 3.1 2.5 3 0 0 3 3 2 2 Syntaxin-like protein SNARE PF05739.19 ORX84005.1 - 2.1e-14 53.2 0.8 2.1e-14 53.2 0.8 2.7 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.25 ORX84005.1 - 9.1e-11 41.8 11.0 1.5e-10 41.1 11.0 1.3 1 0 0 1 1 1 1 Syntaxin DUF2207 PF09972.9 ORX84005.1 - 0.0081 15.0 0.9 0.087 11.6 0.0 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) MCPsignal PF00015.21 ORX84005.1 - 0.014 15.2 4.5 0.24 11.2 0.2 3.0 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HAUS-augmin3 PF14932.6 ORX84005.1 - 0.019 14.5 1.0 0.019 14.5 1.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 COMMD1_N PF17221.3 ORX84005.1 - 0.024 14.9 1.9 0.043 14.1 0.7 1.9 2 0 0 2 2 2 0 COMMD1 N-terminal domain DUF1043 PF06295.12 ORX84005.1 - 0.03 14.3 7.3 0.17 11.8 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Focal_AT PF03623.13 ORX84005.1 - 0.037 14.0 2.4 0.089 12.8 0.2 2.5 3 0 0 3 3 3 0 Focal adhesion targeting region Mobilization_B PF17511.2 ORX84005.1 - 0.059 13.7 0.9 6.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Mobilization protein B DUF1678 PF07913.11 ORX84005.1 - 0.074 12.8 0.1 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1678) DUF1664 PF07889.12 ORX84005.1 - 0.13 12.3 8.7 0.55 10.3 0.8 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) CK2S PF15011.6 ORX84005.1 - 0.19 11.6 5.4 6.3 6.7 5.4 2.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate FlxA PF14282.6 ORX84005.1 - 0.51 10.4 6.2 0.17 11.9 1.0 2.4 2 0 0 2 2 2 0 FlxA-like protein ING PF12998.7 ORX84005.1 - 0.58 10.8 7.8 0.79 10.3 0.7 2.8 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding RasGAP_C PF03836.15 ORX84005.1 - 0.59 10.3 8.4 3.9 7.6 1.0 2.9 2 1 0 2 2 2 0 RasGAP C-terminus MPS2 PF17060.5 ORX84005.1 - 1.5 8.0 11.6 0.18 11.0 5.0 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 ISG65-75 PF11727.8 ORX84005.1 - 3.8 6.7 10.6 0.56 9.4 1.7 2.7 1 1 2 3 3 3 0 Invariant surface glycoprotein SlyX PF04102.12 ORX84005.1 - 8.5 7.1 10.5 0.4 11.3 0.4 3.2 2 2 1 3 3 3 0 SlyX NIF PF03031.18 ORX84006.1 - 2.7e-49 166.9 0.9 3.7e-49 166.5 0.9 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Questin_oxidase PF14027.6 ORX84007.1 - 3.8e-64 217.4 0.3 4.4e-64 217.2 0.3 1.0 1 0 0 1 1 1 1 Questin oxidase-like Fur_reg_FbpB PF13040.6 ORX84007.1 - 0.061 12.9 2.9 1.2 8.7 0.8 2.4 2 0 0 2 2 2 0 Fur-regulated basic protein B Exo_endo_phos PF03372.23 ORX84008.1 - 3.1e-21 75.9 0.0 5.9e-21 75.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ORX84008.1 - 0.1 12.5 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase PilW PF16074.5 ORX84008.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W TMEM192 PF14802.6 ORX84050.1 - 0.27 10.3 3.2 0.84 8.7 0.2 2.3 2 0 0 2 2 2 0 TMEM192 family DUF2975 PF11188.8 ORX84050.1 - 0.8 9.6 7.3 0.87 9.5 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF4866 PF16160.5 ORX84052.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) CD20 PF04103.15 ORX84054.1 - 0.063 13.4 2.4 0.14 12.3 2.4 1.6 1 0 0 1 1 1 0 CD20-like family Trypsin PF00089.26 ORX84055.1 - 3.9e-46 157.6 0.0 4.5e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX84055.1 - 2.7e-08 34.9 0.0 5.3e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF2574 PF10836.8 ORX84056.1 - 0.79 9.6 5.7 2.6 8.0 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) zf-Tim10_DDP PF02953.15 ORX84057.1 - 0.1 12.2 6.4 11 5.8 0.0 2.7 2 1 0 2 2 2 0 Tim10/DDP family zinc finger Plasmodium_Vir PF05795.11 ORX84057.1 - 0.18 11.2 3.2 0.24 10.8 3.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.9 ORX84057.1 - 3.2 6.8 18.9 3.6 6.7 18.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 ORX84058.1 - 2.7e-69 233.5 0.0 3.3e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX84058.1 - 3.8e-35 121.4 0.0 4.9e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX84058.1 - 0.00018 21.0 0.4 0.0003 20.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX84058.1 - 0.00054 19.0 0.3 0.00084 18.4 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX84058.1 - 0.01 15.8 0.3 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family N_Asn_amidohyd PF14736.6 ORX84058.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Kinase-like PF14531.6 ORX84058.1 - 0.042 13.2 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like 4HBT PF03061.22 ORX84059.1 - 2.7e-29 101.3 0.4 1.6e-16 60.4 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily A2M_BRD PF07703.14 ORX84059.1 - 0.094 13.1 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Alpha-2-macroglobulin bait region domain PA26 PF04636.13 ORX84059.1 - 1.7 7.5 4.1 0.6 9.0 0.2 1.9 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) Asn_synthase PF00733.21 ORX84060.1 - 5.9e-92 309.1 0.2 2.7e-88 297.0 0.2 2.2 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORX84060.1 - 7.5e-38 129.2 0.0 1.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX84060.1 - 2e-31 109.0 0.0 3.9e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORX84060.1 - 1.3e-08 34.6 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORX84060.1 - 0.03 13.4 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase ECH_1 PF00378.20 ORX84061.1 - 1.4e-41 142.5 0.0 1.9e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX84061.1 - 9.7e-14 51.6 0.0 1.1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORX84061.1 - 0.052 13.5 0.2 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Carboxyl_trans PF01039.22 ORX84061.1 - 0.062 11.9 0.0 0.091 11.4 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain bZIP_1 PF00170.21 ORX84062.1 - 1.8e-06 27.9 10.9 5.5e-05 23.2 11.3 2.3 1 1 1 2 2 2 2 bZIP transcription factor Zwint PF15556.6 ORX84062.1 - 0.0029 17.1 3.1 0.0046 16.5 3.1 1.2 1 0 0 1 1 1 1 ZW10 interactor DUF3425 PF11905.8 ORX84062.1 - 0.0086 16.0 0.1 0.028 14.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Snapin_Pallidin PF14712.6 ORX84062.1 - 0.014 15.8 1.9 0.033 14.6 1.9 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Sua5_yciO_yrdC PF01300.18 ORX84062.1 - 0.12 11.9 0.1 0.59 9.6 0.4 1.8 2 0 0 2 2 2 0 Telomere recombination G-alpha PF00503.20 ORX84063.1 - 7.3e-116 387.2 6.2 8.5e-116 387.0 6.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX84063.1 - 5.7e-15 55.2 1.5 3e-11 43.1 0.2 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX84063.1 - 2.7e-05 23.6 4.0 0.0003 20.2 0.1 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX84063.1 - 0.0016 18.7 0.2 1.5 9.0 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 ORX84063.1 - 0.0016 18.2 0.2 0.0058 16.4 0.1 1.9 2 0 0 2 2 2 1 CHC2 zinc finger AAA_28 PF13521.6 ORX84063.1 - 0.0077 16.5 0.1 0.017 15.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORX84063.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX84063.1 - 0.016 15.3 0.0 7.4 6.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORX84063.1 - 0.11 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF726 PF05277.12 ORX84152.1 - 2.2e-78 263.6 0.0 2.6e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 ORX84152.1 - 0.012 16.3 0.1 0.019 15.6 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ORX84152.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain GPI-anchored PF10342.9 ORX84153.1 - 5e-06 27.2 0.3 5e-06 27.2 0.3 2.8 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.17 ORX84153.1 - 2.1 8.3 23.6 0.63 10.0 14.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CybS PF05328.12 ORX84154.1 - 8.9e-25 86.9 0.1 1.1e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Forkhead PF00250.18 ORX84200.1 - 4.4e-33 113.4 0.5 4.7e-33 113.3 0.5 1.0 1 0 0 1 1 1 1 Forkhead domain Sugar_tr PF00083.24 ORX84201.1 - 2.3e-100 336.6 23.5 2.9e-100 336.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX84201.1 - 6.1e-29 101.0 33.6 2.3e-28 99.1 27.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily YdfA_immunity PF12127.8 ORX84201.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial Hydrolase_4 PF12146.8 ORX84202.1 - 3.2e-14 52.8 0.0 2.9e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX84202.1 - 2.4e-11 43.8 0.1 2.4e-08 33.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ORX84202.1 - 1.2e-05 25.0 0.0 4.3e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ORX84202.1 - 3e-05 22.9 0.1 0.0058 15.4 0.0 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ORX84202.1 - 3e-05 23.9 0.1 0.021 14.6 0.1 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 ORX84202.1 - 0.00016 21.7 0.0 0.083 12.8 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 ORX84202.1 - 0.00024 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORX84202.1 - 0.00027 21.6 0.0 0.0005 20.7 0.0 1.5 2 0 0 2 2 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX84202.1 - 0.00068 19.2 0.0 0.0042 16.6 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 ORX84202.1 - 0.0022 17.6 0.0 0.97 8.9 0.0 2.3 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 ORX84202.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF818 PF05677.12 ORX84202.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.18 ORX84202.1 - 0.074 12.6 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) RHD3 PF05879.12 ORX84203.1 - 4.4e-230 765.8 22.9 7.8e-205 682.3 13.7 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 ORX84203.1 - 1.5e-06 28.3 0.1 5e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORX84203.1 - 6.6e-06 26.3 0.0 6.6e-06 26.3 0.0 2.9 2 1 0 2 2 2 1 Dynamin family GBP PF02263.19 ORX84203.1 - 5.8e-05 22.5 0.2 5.8e-05 22.5 0.2 2.4 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 ORX84203.1 - 0.0037 17.5 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORX84203.1 - 0.021 14.7 0.3 0.39 10.6 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase Septin PF00735.18 ORX84203.1 - 0.027 13.7 0.1 0.11 11.8 0.1 2.1 1 0 0 1 1 1 0 Septin NCE101 PF11654.8 ORX84203.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 EF-G-binding_N PF07299.11 ORX84203.1 - 0.36 11.4 3.1 4.7 7.8 1.0 3.0 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF4996 PF16387.5 ORX84203.1 - 0.62 10.6 2.5 3.2 8.3 0.6 3.1 1 1 2 3 3 3 0 Domain of unknown function FlgD_ig PF13860.6 ORX84204.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain Glyoxal_oxid_N PF07250.11 ORX84206.1 - 9.2e-56 188.7 0.1 1.2e-53 181.8 0.0 3.4 2 2 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORX84206.1 - 5.2e-30 103.6 0.2 1.2e-29 102.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 ORX84206.1 - 0.0049 17.1 0.0 40 4.7 0.0 4.7 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 ORX84206.1 - 0.024 14.6 1.0 6.1 6.9 0.0 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF5122 PF17164.4 ORX84206.1 - 0.048 14.0 0.1 45 4.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller CBM9_1 PF06452.11 ORX84208.1 - 0.00012 22.1 0.1 0.00031 20.7 0.1 1.8 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like Tubulin PF00091.25 ORX84209.1 - 2.7e-60 203.9 0.0 6.1e-60 202.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX84209.1 - 8.2e-42 142.3 0.1 1.3e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX84209.1 - 2e-05 24.9 0.1 5.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORX84209.1 - 0.00087 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORX84209.1 - 0.0036 16.5 0.2 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Tubulin like YchF-GTPase_C PF06071.13 ORX84210.1 - 1.1e-38 131.3 0.7 2.7e-38 130.0 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORX84210.1 - 6.9e-23 80.9 0.0 2.2e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX84210.1 - 1.2e-07 31.3 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORX84210.1 - 0.00041 20.5 0.1 1.1 9.4 0.1 2.7 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 ORX84210.1 - 0.021 13.8 0.0 0.055 12.5 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ORX84210.1 - 0.033 14.4 0.0 0.63 10.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 ORX84210.1 - 0.047 13.5 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 ORX84210.1 - 0.062 13.8 0.1 1.3 9.5 0.0 2.9 3 1 0 3 3 3 0 AAA domain TGS PF02824.21 ORX84210.1 - 0.083 13.0 0.1 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 TGS domain Ldh_1_N PF00056.23 ORX84211.1 - 1.1e-34 119.5 1.2 1.6e-34 119.0 1.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX84211.1 - 1.6e-23 83.4 0.1 4.2e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TrkA_N PF02254.18 ORX84211.1 - 4.5e-05 23.7 0.1 7.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 ORX84211.1 - 0.00023 20.8 1.0 0.0014 18.3 1.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORX84211.1 - 0.00097 19.7 1.1 0.0049 17.4 0.4 2.3 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 ORX84211.1 - 0.0011 18.6 0.9 0.0022 17.7 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORX84211.1 - 0.0023 17.8 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX84211.1 - 0.017 15.1 0.2 0.36 10.8 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 ORX84211.1 - 0.023 14.7 0.4 0.062 13.4 0.4 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORX84211.1 - 0.041 14.3 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ORX84211.1 - 0.057 13.0 0.3 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ORX84211.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoMet_dc PF02675.15 ORX84211.1 - 0.085 13.1 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 1 0 S-adenosylmethionine decarboxylase Glyco_hydro_4 PF02056.16 ORX84211.1 - 0.22 11.1 3.0 1.7 8.2 0.4 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Cyclin PF08613.11 ORX84212.1 - 3.8e-27 95.6 0.9 1.7e-26 93.5 0.7 1.7 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX84212.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Big_5 PF13205.6 ORX84213.1 - 0.14 12.9 0.1 0.31 11.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain Ammonium_transp PF00909.21 ORX84214.1 - 1.7e-108 362.9 29.7 1.9e-108 362.7 29.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family LPMO_10 PF03067.15 ORX84215.1 - 0.0002 22.1 0.1 0.0023 18.6 0.0 2.5 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX84215.1 - 0.0049 16.8 0.0 0.04 13.9 0.0 2.4 1 1 2 3 3 3 1 Glycosyl hydrolase family 61 Epiglycanin_TR PF05647.11 ORX84215.1 - 2 8.4 7.5 3.5 7.6 7.5 1.4 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like CBM_14 PF01607.24 ORX84215.1 - 3.9 7.7 7.2 3.8 7.8 5.4 2.0 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain LPMO_10 PF03067.15 ORX84216.1 - 0.0002 22.1 0.1 0.0023 18.6 0.0 2.5 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX84216.1 - 0.0049 16.8 0.0 0.04 13.9 0.0 2.4 1 1 2 3 3 3 1 Glycosyl hydrolase family 61 Epiglycanin_TR PF05647.11 ORX84216.1 - 2 8.4 7.5 3.5 7.6 7.5 1.4 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like CBM_14 PF01607.24 ORX84216.1 - 3.9 7.7 7.2 3.8 7.8 5.4 2.0 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain His_Phos_1 PF00300.22 ORX84261.1 - 9e-18 64.7 0.0 3.2e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ORX84261.1 - 0.0049 16.3 0.1 0.021 14.2 0.1 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Nfu_N PF08712.11 ORX84262.1 - 3.1e-29 100.8 0.0 8.4e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORX84262.1 - 1.3e-28 98.9 0.1 2.2e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain RRM_1 PF00076.22 ORX84263.1 - 1.9e-31 107.7 0.1 5.3e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX84263.1 - 0.00014 21.8 0.2 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Presenilin PF01080.17 ORX84263.1 - 0.13 11.0 21.4 0.26 10.0 21.4 1.5 1 0 0 1 1 1 0 Presenilin Mitofilin PF09731.9 ORX84263.1 - 0.38 9.5 26.8 0.49 9.2 26.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nop14 PF04147.12 ORX84263.1 - 0.52 8.5 39.3 0.96 7.6 39.3 1.3 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 ORX84263.1 - 0.88 8.2 10.9 1.2 7.8 10.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Astro_capsid_p PF12226.8 ORX84263.1 - 3 6.9 21.7 4.8 6.2 21.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2151 PF10221.9 ORX84263.1 - 3.9 5.9 23.2 6 5.3 23.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Raftlin PF15250.6 ORX84263.1 - 6.7 5.3 19.9 12 4.4 19.9 1.4 1 0 0 1 1 1 0 Raftlin PI3K_1B_p101 PF10486.9 ORX84263.1 - 7 4.3 15.0 8.3 4.0 15.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM60A PF15396.6 ORX84263.1 - 7.1 6.6 27.7 2.4 8.1 24.7 1.7 2 0 0 2 2 2 0 Protein Family FAM60A Smg8_Smg9 PF10220.9 ORX84263.1 - 7.2 4.8 19.3 11 4.2 19.3 1.2 1 0 0 1 1 1 0 Smg8_Smg9 SLC12 PF03522.15 ORX84263.1 - 7.5 5.5 21.5 18 4.2 21.5 1.6 1 0 0 1 1 1 0 Solute carrier family 12 LRR_6 PF13516.6 ORX84264.1 - 2.9e-17 61.2 11.7 0.11 12.7 0.0 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 ORX84264.1 - 6.9e-15 54.9 6.6 0.023 15.1 0.0 7.3 4 3 2 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORX84264.1 - 9.3e-12 44.7 4.1 9.3e-12 44.7 4.1 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORX84264.1 - 7e-05 22.6 11.4 9.1e-05 22.2 4.6 3.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORX84264.1 - 0.72 10.6 17.8 14 6.7 0.0 7.7 8 0 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 ORX84264.1 - 5.1 7.4 8.7 22 5.4 0.1 3.9 3 2 1 4 4 4 0 Ste50p, sterile alpha motif TRAPPC10 PF12584.8 ORX84265.1 - 2.2e-15 56.7 0.0 4.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 ORX84265.1 - 0.034 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Vps26 PF03643.15 ORX84265.1 - 0.042 12.9 0.2 0.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Glyco_hydro_17 PF00332.18 ORX84305.1 - 1.8e-12 47.5 1.2 2.2e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Calmodulin_bind PF07887.11 ORX84305.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Calmodulin binding protein-like Dicty_CAR PF05462.11 ORX84306.1 - 0.0014 17.9 9.3 0.0024 17.1 9.2 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor RXT2_N PF08595.11 ORX84308.1 - 1.9e-06 28.0 5.3 3.3e-05 24.0 0.1 2.8 1 1 2 3 3 3 2 RXT2-like, N-terminal GCV_H PF01597.19 ORX84309.1 - 0.00042 20.2 0.2 0.004 17.0 0.1 2.1 2 0 0 2 2 2 1 Glycine cleavage H-protein AhpC-TSA PF00578.21 ORX84310.1 - 1.6e-34 118.5 0.0 2.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX84310.1 - 7.7e-12 45.2 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORX84310.1 - 3.3e-09 36.4 0.0 5.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box-like PF12937.7 ORX84311.1 - 2.5e-12 46.5 0.1 1.1e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORX84311.1 - 3.7e-08 33.1 1.1 6.9e-08 32.2 1.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORX84311.1 - 0.014 15.2 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 F-box PRANC PF09372.10 ORX84311.1 - 0.017 15.5 0.1 0.033 14.5 0.0 1.5 1 1 0 1 1 1 0 PRANC domain LPMO_10 PF03067.15 ORX84353.1 - 4.9e-05 24.1 0.1 0.00012 22.8 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX84353.1 - 0.022 14.7 0.3 0.25 11.3 0.3 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Voltage_CLC PF00654.20 ORX84354.1 - 3.3e-98 329.2 17.1 3.3e-98 329.2 17.1 2.2 1 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORX84354.1 - 2.5e-07 31.0 0.0 9.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 CBS domain DUF3938 PF13074.6 ORX84354.1 - 0.023 14.9 0.4 0.074 13.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) PDR_CDR PF06422.12 ORX84354.1 - 1.1 9.2 4.9 3 7.8 0.1 3.3 2 0 0 2 2 2 0 CDR ABC transporter TAT_signal PF10518.9 ORX84354.1 - 5.7 6.9 9.0 2.9 7.9 0.6 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence FH2 PF02181.23 ORX84355.1 - 0.015 14.4 0.2 0.018 14.2 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Reovirus_M2 PF05993.12 ORX84355.1 - 0.055 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Cpn60_TCP1 PF00118.24 ORX84356.1 - 1.4e-159 531.9 5.5 1.6e-159 531.7 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CAP_C PF08603.11 ORX84357.1 - 0.0034 17.0 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal RsgA_GTPase PF03193.16 ORX84358.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 ORX84358.1 - 0.031 14.8 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 ORX84358.1 - 0.13 12.1 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C2H2 PF00096.26 ORX84359.1 - 1.5e-10 40.9 9.6 4.4e-05 23.7 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX84359.1 - 5.5e-10 39.2 8.2 1.7e-05 25.3 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX84359.1 - 1.5e-09 37.8 13.4 3e-09 36.9 3.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX84359.1 - 1.9e-05 24.8 1.0 0.2 12.0 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX84359.1 - 0.00057 19.8 2.4 0.43 10.7 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.18 ORX84359.1 - 0.00081 20.0 1.9 0.00099 19.8 1.9 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger zf_UBZ PF18439.1 ORX84359.1 - 0.00082 18.9 0.8 0.054 13.1 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 ORX84359.1 - 0.0012 19.1 1.4 0.0017 18.6 1.4 1.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 ORX84359.1 - 0.011 15.5 1.9 0.056 13.2 0.2 2.0 1 1 1 2 2 2 0 GAGA factor zf-H2C2_5 PF13909.6 ORX84359.1 - 0.011 15.5 0.3 0.011 15.5 0.3 3.3 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 ORX84359.1 - 0.015 15.7 1.5 2.7 8.5 0.4 2.9 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 ORX84359.1 - 0.049 13.8 1.1 7.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain FOXP-CC PF16159.5 ORX84359.1 - 0.07 13.8 0.4 11 6.7 0.0 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 ORX84359.1 - 0.1 12.3 1.5 0.46 10.2 0.9 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 ORX84359.1 - 0.26 11.7 4.8 4.6 7.8 0.8 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RhoGAP PF00620.27 ORX84360.1 - 8.1e-43 145.9 0.0 2.9e-42 144.1 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 ORX84360.1 - 1.1e-17 64.4 0.0 4.2e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 PH domain PX PF00787.24 ORX84360.1 - 4.6e-11 42.7 0.2 2.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 PX domain PH_11 PF15413.6 ORX84360.1 - 8.3e-05 23.0 2.0 0.00012 22.4 0.3 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 ORX84360.1 - 0.00054 20.2 0.0 0.0017 18.6 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain GST_N_3 PF13417.6 ORX84361.1 - 8.9e-19 67.7 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX84361.1 - 1.6e-15 57.1 0.0 3.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORX84361.1 - 3.9e-15 55.9 0.0 1.2e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX84361.1 - 4.7e-08 33.0 0.0 8.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX84361.1 - 2.2e-05 24.6 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX84361.1 - 9.1e-05 22.6 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX84361.1 - 0.00035 21.1 0.0 0.00055 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SLH PF00395.20 ORX84361.1 - 0.002 18.1 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 S-layer homology domain Glutaredoxin PF00462.24 ORX84361.1 - 0.027 14.7 0.0 0.082 13.1 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin Mem_trans PF03547.18 ORX84404.1 - 0.2 10.0 0.3 0.27 9.6 0.3 1.1 1 0 0 1 1 1 0 Membrane transport protein NAD_binding_2 PF03446.15 ORX84405.1 - 3.8e-44 150.6 0.9 6e-44 150.0 0.9 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORX84405.1 - 9.1e-32 109.9 0.0 1.9e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORX84405.1 - 4.4e-06 27.2 0.0 1.4e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX84405.1 - 0.0028 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 ORX84405.1 - 0.0067 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 3HCDH_N PF02737.18 ORX84405.1 - 0.035 14.0 0.0 0.077 12.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2007 PF09413.10 ORX84405.1 - 0.043 14.0 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein ECH_1 PF00378.20 ORX84406.1 - 5e-87 291.4 0.3 5.5e-87 291.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX84406.1 - 4.8e-34 118.4 0.8 2.2e-31 109.6 0.5 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORX84406.1 - 0.024 14.6 0.1 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 BTB_2 PF02214.22 ORX84407.1 - 0.0098 16.2 0.0 0.029 14.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain AEP1 PF17049.5 ORX84407.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 ATPase expression protein 1 DNA_methylase PF00145.17 ORX84408.1 - 4.3e-41 141.4 0.0 1e-40 140.2 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 ORX84408.1 - 1.3e-05 25.0 1.3 0.00016 21.5 0.2 2.5 2 0 0 2 2 2 1 BAH domain DNMT1-RFD PF12047.8 ORX84408.1 - 1.4e-05 25.1 0.1 4.8e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain IucA_IucC PF04183.12 ORX84409.1 - 4.4e-20 72.3 0.0 7.1e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 ORX84409.1 - 4.7e-14 53.1 0.0 1.9e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter MMR_HSR1 PF01926.23 ORX84411.1 - 4e-16 59.1 0.1 2.2e-14 53.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX84411.1 - 5.7e-08 32.4 0.2 4.4e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX84411.1 - 1.8e-05 24.7 0.3 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 ORX84411.1 - 0.00077 19.1 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 ORX84411.1 - 0.0057 16.7 8.4 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 Dynamin family CDC45 PF02724.14 ORX84411.1 - 0.024 12.9 10.8 0.044 12.1 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 ORX84411.1 - 0.033 14.5 14.8 0.077 13.2 14.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AIG1 PF04548.16 ORX84411.1 - 0.05 12.9 1.8 0.053 12.8 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Saw1 PF11561.8 ORX84411.1 - 1.5 8.3 5.0 2.8 7.4 5.0 1.5 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF913 PF06025.12 ORX84411.1 - 1.5 7.7 4.7 2.6 6.9 4.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 ORX84411.1 - 9.4 5.5 16.2 16 4.7 16.2 1.3 1 0 0 1 1 1 0 NOA36 protein RRG8 PF17068.5 ORX84412.1 - 0.79 9.1 4.5 2.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Required for respiratory growth protein 8 mitochondrial HMG_box PF00505.19 ORX84413.1 - 1.1e-43 147.4 11.2 7.2e-22 77.6 0.2 3.9 4 0 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX84413.1 - 3.4e-32 110.9 10.6 2.1e-15 57.1 0.1 3.7 4 0 0 4 4 4 3 HMG-box domain CHDNT PF08073.12 ORX84413.1 - 4e-06 26.7 0.2 0.077 13.0 0.0 2.6 2 0 0 2 2 2 2 CHDNT (NUC034) domain HMG_box_5 PF14887.6 ORX84413.1 - 0.00023 21.1 1.8 0.00041 20.3 0.2 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box 5 BRK PF07533.16 ORX84413.1 - 0.015 14.9 0.0 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 BRK domain Protamine_like PF06382.11 ORX84413.1 - 0.22 11.7 2.7 0.33 11.1 1.7 1.9 1 1 1 2 2 2 0 Protamine and protamine like CBAH PF02275.18 ORX84415.1 - 0.016 14.8 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family pKID PF02173.17 ORX84461.1 - 0.075 12.5 1.0 0.22 11.0 1.0 1.8 1 0 0 1 1 1 0 pKID domain RNAse_A_bac PF18431.1 ORX84461.1 - 0.076 14.0 0.0 0.12 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain RBD-FIP PF09457.10 ORX84461.1 - 0.22 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 FIP domain GRP PF07172.11 ORX84464.1 - 3.4 8.4 23.4 2.7 8.7 22.0 1.5 1 1 1 2 2 2 0 Glycine rich protein family tRNA_SAD PF07973.14 ORX84465.1 - 0.17 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Vps54 PF07928.12 ORX84510.1 - 0.05 14.1 0.3 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Vps54-like protein DUF4728 PF15860.5 ORX84512.1 - 0.00029 21.4 3.8 0.00029 21.4 3.8 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4728) Tetraspanin PF00335.20 ORX84512.1 - 0.002 17.9 12.5 0.002 17.9 12.5 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF4064 PF13273.6 ORX84512.1 - 2.5 8.4 13.4 1.7 9.0 9.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) AC_N PF16214.5 ORX84512.1 - 7.4 5.6 5.9 13 4.8 5.9 1.4 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region GtrA PF04138.14 ORX84513.1 - 0.01 16.0 7.5 0.13 12.5 4.1 2.5 3 0 0 3 3 3 0 GtrA-like protein Tetraspanin PF00335.20 ORX84514.1 - 0.0076 16.0 5.4 0.011 15.5 5.4 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF4728 PF15860.5 ORX84514.1 - 0.012 16.2 6.9 0.038 14.7 6.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) Tetraspanin PF00335.20 ORX84515.1 - 0.0004 20.2 6.4 0.00087 19.1 6.4 1.6 1 1 1 2 2 2 1 Tetraspanin family DUF4728 PF15860.5 ORX84515.1 - 0.00071 20.2 3.4 0.0019 18.8 3.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4728) Caa3_CtaG PF09678.10 ORX84515.1 - 0.0082 15.6 0.6 0.012 15.1 0.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF2569 PF10754.9 ORX84515.1 - 0.013 15.9 2.2 0.023 15.2 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) CD20 PF04103.15 ORX84515.1 - 0.037 14.1 4.2 0.037 14.1 4.2 1.7 1 1 0 1 1 1 0 CD20-like family DUF2678 PF10856.8 ORX84515.1 - 0.041 13.8 0.4 0.08 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) TssN PF17555.2 ORX84515.1 - 1.9 7.8 4.4 0.29 10.5 1.0 1.3 2 0 0 2 2 2 0 Type VI secretion system, TssN Arrestin_C PF02752.22 ORX84516.1 - 2.1e-11 44.4 0.4 5.5e-10 39.8 0.7 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX84516.1 - 3.3e-08 33.7 0.0 1e-06 28.9 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX84516.1 - 0.008 15.9 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 ORX84517.1 - 1.4e-09 38.1 0.3 9.4e-06 25.7 0.1 2.8 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX84517.1 - 0.014 15.1 0.0 0.23 11.1 0.0 2.4 2 1 1 3 3 3 0 Arrestin_N terminal like QueC PF06508.13 ORX84517.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC CBM_21 PF03370.13 ORX84517.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) Aa_trans PF01490.18 ORX84518.1 - 4.4e-46 157.4 24.2 4.4e-46 157.4 24.2 1.4 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX84518.1 - 2.1e-06 26.8 9.8 2.1e-06 26.8 9.8 2.3 2 2 0 2 2 2 1 Spore germination protein ERGIC_N PF13850.6 ORX84518.1 - 1.1 9.7 5.6 0.62 10.4 0.7 3.0 3 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HSP70 PF00012.20 ORX84562.1 - 1.2e-262 872.5 6.6 1.3e-262 872.3 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX84562.1 - 1.8e-16 59.9 0.1 3.3e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX84562.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX84562.1 - 0.01 15.1 0.1 0.024 13.9 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX84562.1 - 0.016 14.7 0.0 4.8 6.6 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX84562.1 - 0.08 13.2 4.8 0.82 9.9 0.9 2.4 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX84562.1 - 0.082 12.9 0.5 0.21 11.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DDR PF08841.10 ORX84562.1 - 0.094 11.7 0.3 0.82 8.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Phage_lysozyme PF00959.19 ORX84563.1 - 2.1e-05 24.9 0.0 3.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme Mito_morph_reg PF14972.6 ORX84568.1 - 0.11 12.1 0.5 0.12 12.0 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Xan_ur_permease PF00860.20 ORX84569.1 - 5.3e-64 216.3 32.9 1.4e-62 211.6 32.9 2.1 1 1 0 1 1 1 1 Permease family ABC_tran PF00005.27 ORX84570.1 - 5.4e-25 88.5 0.0 1.2e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX84570.1 - 1.3e-19 70.5 21.8 1.9e-19 70.0 21.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX84570.1 - 6.5e-07 29.5 0.1 0.0006 19.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORX84570.1 - 0.065 13.6 0.0 0.3 11.4 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORX84570.1 - 0.12 12.9 0.6 0.91 9.9 0.6 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Holin_BhlA PF10960.8 ORX84570.1 - 2.4 8.2 4.5 11 6.0 0.0 3.1 3 0 0 3 3 3 0 BhlA holin family Cys_Met_Meta_PP PF01053.20 ORX84571.1 - 5.2e-156 519.0 0.3 5.9e-156 518.8 0.3 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORX84571.1 - 6.4e-08 31.9 0.4 1.2e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORX84571.1 - 4.6e-06 26.0 0.0 6.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORX84571.1 - 0.00075 18.9 0.8 0.0013 18.2 0.3 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 ORX84571.1 - 0.034 13.0 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Allinase Mannosyl_trans2 PF04188.13 ORX84572.1 - 5.4e-05 22.7 0.1 5.4e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PRELI PF04707.14 ORX84623.1 - 1.5e-42 145.0 0.0 1.9e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family zf-C2H2 PF00096.26 ORX84624.1 - 1.5e-11 44.0 8.8 3.8e-06 27.1 0.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX84624.1 - 2.1e-08 34.3 6.9 0.0003 21.4 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX84624.1 - 7.5e-07 29.3 3.0 7.5e-07 29.3 3.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX84624.1 - 2e-05 24.5 2.2 0.0047 16.9 0.1 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX84624.1 - 0.0067 16.8 1.6 0.17 12.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX84624.1 - 0.012 15.9 0.6 0.021 15.1 0.6 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORX84624.1 - 0.026 14.8 1.2 0.034 14.4 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX84624.1 - 0.037 14.7 0.7 0.15 12.7 0.2 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain YABBY PF04690.13 ORX84625.1 - 0.035 14.7 1.7 0.051 14.2 1.7 1.2 1 0 0 1 1 1 0 YABBY protein SMN PF06003.12 ORX84625.1 - 0.1 11.8 1.4 0.13 11.5 1.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4629 PF15442.6 ORX84625.1 - 0.12 12.7 4.7 0.11 12.7 3.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) CEND1 PF15677.5 ORX84625.1 - 0.45 11.1 4.0 0.62 10.6 4.0 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Gcd10p PF04189.13 ORX84626.1 - 1.5e-76 257.4 1.9 2.5e-76 256.7 1.9 1.3 1 0 0 1 1 1 1 Gcd10p family Tyrosinase PF00264.20 ORX84628.1 - 7.4e-34 118.0 2.3 1.2e-32 114.0 2.3 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase zf-LITAF-like PF10601.9 ORX84629.1 - 2.4e-21 75.8 3.6 3.1e-21 75.4 3.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Integrase_H2C2 PF17921.1 ORX84629.1 - 0.00081 19.5 0.8 0.00081 19.5 0.8 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Rubredoxin PF00301.20 ORX84629.1 - 0.056 13.5 1.8 0.28 11.2 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin HypA PF01155.19 ORX84629.1 - 0.076 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_7 PF02591.15 ORX84629.1 - 0.076 13.2 5.9 1.9 8.7 1.6 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 ORX84629.1 - 0.14 12.2 5.9 2.3 8.3 0.4 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Sgf11 PF08209.11 ORX84629.1 - 0.32 10.6 7.1 2.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf_Rg PF17915.1 ORX84629.1 - 2.6 7.5 6.3 6.2 6.3 0.3 2.3 2 0 0 2 2 2 0 Reverse gyrase zinc finger RGS PF00615.19 ORX84630.1 - 1.1e-14 54.7 1.1 1.6e-14 54.2 1.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain UBA_5 PF16577.5 ORX84630.1 - 0.016 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 UBA domain Hydrolase_2 PF07486.12 ORX84630.1 - 0.054 14.4 0.0 0.17 12.8 0.0 1.8 1 0 0 1 1 1 0 Cell Wall Hydrolase UPF0121 PF03661.13 ORX84631.1 - 1.8e-40 138.8 5.3 2.2e-40 138.6 5.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) LETM1 PF07766.13 ORX84631.1 - 0.058 12.7 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 LETM1-like protein WH1 PF00568.23 ORX84632.1 - 3.6e-26 91.3 0.1 5.3e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORX84632.1 - 1.9e-16 60.2 0.1 3.5e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain DCP1 PF06058.13 ORX84632.1 - 0.028 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family Actin PF00022.19 ORX84636.1 - 2.8e-82 276.5 0.0 1.3e-80 271.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORX84636.1 - 0.00036 19.5 0.0 0.024 13.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORX84636.1 - 0.036 14.5 0.0 0.081 13.4 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA Ribosomal_L7Ae PF01248.26 ORX84637.1 - 1.4e-24 85.6 0.0 1.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HABP4_PAI-RBP1 PF04774.15 ORX84638.1 - 9.9e-06 26.4 13.1 9.9e-06 26.4 13.1 3.7 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 ORX84638.1 - 9e-05 23.2 5.4 9e-05 23.2 5.4 3.5 2 1 0 2 2 2 1 Stm1 GRP PF07172.11 ORX84638.1 - 0.025 15.3 3.7 0.025 15.3 3.7 3.0 2 1 1 3 3 3 0 Glycine rich protein family GPHH PF16905.5 ORX84685.1 - 1.9e-06 27.5 0.6 81 3.1 0.0 7.6 9 0 0 9 9 9 6 Voltage-dependent L-type calcium channel, IQ-associated GPHH PF16905.5 ORX84686.1 - 0.0014 18.3 0.3 38 4.1 0.0 4.8 6 0 0 6 6 6 3 Voltage-dependent L-type calcium channel, IQ-associated Hydrolase_4 PF12146.8 ORX84724.1 - 3.8e-51 173.7 0.0 4.4e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX84724.1 - 1.2e-17 64.4 0.8 3.9e-13 49.6 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX84724.1 - 7.3e-14 52.9 0.0 1.1e-13 52.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX84724.1 - 1.8e-06 27.6 1.7 5.7e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX84724.1 - 2.8e-05 24.0 0.3 1.2 8.9 0.1 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 ORX84724.1 - 0.0011 17.7 0.3 0.0015 17.3 0.3 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein RMMBL PF07521.12 ORX84724.1 - 0.011 15.7 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain DLH PF01738.18 ORX84724.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DP PF08781.10 ORX84725.1 - 0.02 14.8 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Transcription factor DP CBM_19 PF03427.13 ORX84725.1 - 0.05 13.6 2.8 0.086 12.8 2.8 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Baculo_VP91_N PF08475.10 ORX84725.1 - 0.44 10.2 4.4 1 9.0 4.4 1.7 1 1 0 1 1 1 0 Viral capsid protein 91 N-terminal zf-LITAF-like PF10601.9 ORX84774.1 - 1.9e-16 60.1 12.7 2.5e-16 59.7 12.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C4_Topoisom PF01396.19 ORX84774.1 - 0.039 13.8 0.9 2.7 7.8 0.2 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger UPF0547 PF10571.9 ORX84774.1 - 0.046 13.8 2.3 1 9.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.6 ORX84774.1 - 0.36 10.7 14.1 0.52 10.2 1.8 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX84774.1 - 6.9 6.6 14.8 4.8 7.1 0.3 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 GCP_N_terminal PF17681.1 ORX84775.1 - 3.2e-33 115.7 0.1 4.8e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORX84775.1 - 1.7e-28 100.0 1.7 3e-28 99.2 1.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Cbl_N2 PF02761.14 ORX84775.1 - 0.16 12.7 0.6 1.3 9.8 0.1 2.7 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Popeye PF04831.13 ORX84776.1 - 0.3 11.3 2.8 0.37 11.0 2.8 1.1 1 0 0 1 1 1 0 Popeye protein conserved region Cortexin PF11057.8 ORX84776.1 - 0.88 9.5 3.8 0.43 10.5 0.3 2.0 1 1 1 2 2 2 0 Cortexin of kidney Fijivirus_P9-2 PF06837.11 ORX84776.1 - 4.2 6.8 6.8 5.2 6.5 6.8 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein Pre-PUA PF17832.1 ORX84777.1 - 3.6e-29 101.3 0.2 5.4e-29 100.7 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 ORX84777.1 - 7.3e-18 64.3 0.0 1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 PUA domain COPIIcoated_ERV PF07970.12 ORX84778.1 - 1.4e-84 283.4 1.2 1.4e-84 283.4 1.2 1.4 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORX84778.1 - 3.3e-28 97.9 0.7 1.1e-27 96.2 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SecG PF03840.14 ORX84778.1 - 0.49 10.5 4.1 0.81 9.8 0.1 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit R3H PF01424.22 ORX84779.1 - 6.8e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain Alginate_lyase PF05426.12 ORX84781.1 - 9.8e-51 172.9 0.0 1.2e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase ANAPC3 PF12895.7 ORX84781.1 - 0.0011 19.1 1.7 0.02 15.1 0.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 2OG-FeII_Oxy_2 PF13532.6 ORX84782.1 - 7.7e-17 62.1 0.0 1.9e-14 54.3 0.0 2.1 1 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Glyco_transf_34 PF05637.12 ORX84783.1 - 6.7e-40 137.3 1.9 2.1e-37 129.1 1.9 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORX84783.1 - 0.00012 22.1 0.1 0.00016 21.7 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 ORX84783.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 DUF309 PF03745.14 ORX84783.1 - 0.084 12.6 0.3 0.39 10.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF309) E1-E2_ATPase PF00122.20 ORX84784.1 - 2.6e-42 144.4 3.7 2.6e-42 144.4 3.7 2.4 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX84784.1 - 8.8e-37 127.4 0.6 3.7e-36 125.4 0.6 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORX84784.1 - 1.8e-09 37.9 0.4 5.8e-09 36.3 0.4 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORX84784.1 - 2.3e-06 27.6 1.0 0.001 18.9 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX84784.1 - 0.00015 22.2 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Otopetrin PF03189.13 ORX84784.1 - 0.052 12.4 0.9 0.084 11.7 0.9 1.3 1 0 0 1 1 1 0 Otopetrin ApoO PF09769.9 ORX84785.1 - 2.4e-28 98.7 3.3 2.2e-27 95.6 0.1 2.4 1 1 1 2 2 2 1 Apolipoprotein O Metallophos_3 PF14582.6 ORX84785.1 - 0.0016 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily MIEAP PF16026.5 ORX84785.1 - 0.051 13.8 3.4 0.056 13.6 0.2 2.0 2 0 0 2 2 2 0 Mitochondria-eating protein DUF3713 PF12506.8 ORX84785.1 - 0.053 13.8 1.4 1.6 9.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) SpecificRecomb PF10136.9 ORX84785.1 - 0.063 11.6 2.6 0.069 11.5 1.4 1.5 1 1 1 2 2 2 0 Site-specific recombinase DUF5404 PF17397.2 ORX84785.1 - 0.08 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5404) ApoLp-III PF07464.11 ORX84785.1 - 0.099 12.7 13.8 0.31 11.1 0.6 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PhaP_Bmeg PF09602.10 ORX84785.1 - 0.17 11.8 5.7 0.31 11.0 0.4 2.2 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) IFT57 PF10498.9 ORX84785.1 - 1.3 8.0 10.7 1.4 7.8 1.0 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF2203 PF09969.9 ORX84785.1 - 3.4 8.4 6.1 0.8 10.4 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF883 PF05957.13 ORX84785.1 - 3.7 8.2 5.3 42 4.8 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ORX84785.1 - 7.5 7.2 8.7 1.4 9.5 0.4 3.0 3 0 0 3 3 3 0 YtxH-like protein UCH PF00443.29 ORX84786.1 - 8.3e-65 218.8 0.9 9.6e-65 218.6 0.9 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX84786.1 - 5.8e-17 62.3 6.2 3.3e-16 59.8 1.4 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF952 PF06108.12 ORX84787.1 - 6.8e-16 58.1 0.0 8.5e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Oxysterol_BP PF01237.18 ORX84788.1 - 3.8e-133 443.9 0.2 6.1e-133 443.3 0.2 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 ORX84788.1 - 2.2e-21 76.2 6.5 4e-10 40.1 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX84788.1 - 2.6e-13 48.8 0.6 0.00042 20.6 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORX84788.1 - 3.2e-13 49.6 1.0 2.8e-06 27.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX84788.1 - 3.4e-13 49.8 0.3 1.8e-07 31.5 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.29 ORX84788.1 - 1.2e-12 48.3 1.8 1.1e-11 45.1 0.0 2.7 2 0 0 2 2 2 1 PH domain Ank PF00023.30 ORX84788.1 - 1.8e-12 47.1 5.0 0.00078 19.8 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.6 ORX84788.1 - 1.8e-06 28.2 0.2 5.4e-06 26.6 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 ORX84788.1 - 6.7e-06 26.5 1.9 2.8e-05 24.5 0.1 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Arm PF00514.23 ORX84790.1 - 1.5e-30 104.2 0.8 3.1e-05 23.9 0.1 7.7 7 0 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORX84790.1 - 4.7e-15 55.7 0.1 3e-07 30.8 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 ORX84790.1 - 8.8e-14 51.7 0.1 4.3e-06 27.0 0.0 5.0 2 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 ORX84790.1 - 2.7e-09 36.5 0.2 0.5 10.8 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat RICTOR_V PF14668.6 ORX84790.1 - 2.9e-07 30.6 0.0 0.13 12.5 0.0 4.4 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.14 ORX84790.1 - 0.0017 17.7 0.2 1 8.6 0.0 2.2 2 0 0 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORX84790.1 - 0.0018 18.4 0.0 8.3 6.6 0.0 3.8 4 0 0 4 4 4 1 V-ATPase subunit H CTNNBL PF08216.11 ORX84790.1 - 0.0057 16.8 0.1 1.5 9.0 0.1 3.5 2 1 1 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear RIX1 PF08167.12 ORX84790.1 - 0.0059 16.4 0.1 0.075 12.8 0.1 2.6 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis IPT PF01745.16 ORX84790.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Frankia_peptide PF14407.6 ORX84790.1 - 0.083 12.9 0.0 4 7.5 0.0 3.2 3 0 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. K-box PF01486.17 ORX84790.1 - 0.59 10.3 5.0 0.22 11.7 2.0 1.8 2 0 0 2 2 2 0 K-box region Bromodomain PF00439.25 ORX84791.1 - 7.6e-22 77.2 0.1 1.8e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 ORX84792.1 - 2.7e-30 104.0 10.9 1.1e-07 32.4 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 ORX84792.1 - 1.9e-08 33.4 0.9 1.1 7.8 0.0 5.4 3 2 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORX84792.1 - 8.7e-07 29.2 0.7 0.89 9.9 0.0 3.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX84792.1 - 1.5e-05 24.5 0.4 0.23 10.7 0.0 2.8 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 ORX84792.1 - 0.007 16.8 1.0 1.3 9.6 0.1 3.9 4 0 0 4 4 4 1 PQQ-like domain RSN1_7TM PF02714.15 ORX84793.1 - 2.7e-79 266.4 31.7 4.3e-79 265.7 31.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX84793.1 - 2.1e-30 106.2 0.2 3.4e-30 105.6 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORX84793.1 - 1.3e-20 73.7 0.1 1.3e-20 73.7 0.1 3.3 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 ORX84793.1 - 4.5e-08 33.2 0.0 1.3e-07 31.7 0.0 1.7 1 1 1 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter 5_nucleotid_C PF02872.18 ORX84794.1 - 2.4e-37 128.6 0.0 5.1e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORX84794.1 - 1.8e-11 44.9 1.2 4.1e-11 43.8 1.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OxoGdeHyase_C PF16870.5 ORX84849.1 - 6e-49 165.6 0.1 9.7e-49 165.0 0.1 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 ORX84849.1 - 3.7e-39 134.2 0.0 6.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain F-box-like PF12937.7 ORX84850.1 - 4.4e-11 42.5 0.5 7.6e-11 41.7 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX84850.1 - 1.3e-09 37.7 0.4 2.4e-09 36.8 0.4 1.5 1 0 0 1 1 1 1 F-box domain HalOD1 PF18545.1 ORX84851.1 - 0.00026 21.2 6.8 52 4.2 0.1 6.8 5 1 1 6 6 6 5 Halobacterial output domain 1 ECH_1 PF00378.20 ORX84852.1 - 5.6e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX84852.1 - 9.2e-08 31.9 0.0 2.9e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase G-alpha PF00503.20 ORX84853.1 - 6.4e-113 377.5 0.6 7.6e-113 377.3 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX84853.1 - 6e-14 51.9 0.3 1.5e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX84853.1 - 1.7e-06 27.5 0.1 0.00084 18.8 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX84853.1 - 0.0093 16.2 0.5 1.1 9.5 0.0 3.0 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORX84853.1 - 0.07 13.2 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX84853.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 ORX84853.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_28 PF13521.6 ORX84853.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX84853.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family CitMHS PF03600.16 ORX84855.1 - 2.4e-18 66.4 22.6 4.2e-15 55.7 5.4 2.1 1 1 0 2 2 2 2 Citrate transporter Bestrophin PF01062.21 ORX84856.1 - 2.8e-51 174.7 0.2 3.8e-51 174.2 0.2 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Myb_DNA-bind_4 PF13837.6 ORX84857.1 - 5.9e-15 55.4 2.8 5.9e-15 55.4 2.8 2.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX84857.1 - 0.0016 18.5 1.2 0.0016 18.5 1.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain G-alpha PF00503.20 ORX84858.1 - 2.7e-120 401.8 2.7 3.1e-120 401.6 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX84858.1 - 2.1e-14 53.3 0.2 8.5e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX84858.1 - 7.3e-06 25.5 0.1 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX84858.1 - 0.0067 16.6 0.1 2.8 8.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DASH_Dad1 PF08649.10 ORX84858.1 - 0.0092 16.1 1.0 0.068 13.4 0.3 2.4 2 0 0 2 2 2 1 DASH complex subunit Dad1 MMR_HSR1 PF01926.23 ORX84858.1 - 0.014 15.4 0.1 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-CHC2 PF01807.20 ORX84858.1 - 0.044 13.6 0.1 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 ORX84858.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L5e PF17144.4 ORX84859.1 - 1.4e-86 288.6 0.2 1.4e-86 288.6 0.2 2.7 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORX84859.1 - 3.9e-32 111.1 7.7 3.9e-32 111.1 7.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Arrestin_N PF00339.29 ORX84860.1 - 5.8e-09 36.2 0.0 1.9e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX84860.1 - 5.8e-06 26.1 0.0 2.5e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_C PF02752.22 ORX84860.1 - 4.3e-05 24.0 0.2 7.3e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DapB_C PF05173.14 ORX84860.1 - 0.052 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Velvet PF11754.8 ORX84861.1 - 4.9e-72 242.9 0.2 2.9e-43 148.6 0.0 2.1 1 1 1 2 2 2 2 Velvet factor COX7C PF02935.16 ORX84862.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.1 3 1 0 3 3 3 0 Cytochrome c oxidase subunit VIIc Thioredoxin PF00085.20 ORX84912.1 - 2.1e-49 165.7 0.1 8.6e-24 83.5 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 ORX84912.1 - 4.1e-18 66.0 0.0 4.9e-14 52.7 0.0 3.7 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 ORX84912.1 - 2.7e-05 24.6 3.5 0.51 10.8 0.1 4.7 4 2 0 4 4 4 1 Thioredoxin-like domain TraF PF13728.6 ORX84912.1 - 0.0005 20.0 0.0 0.81 9.5 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 ORX84912.1 - 0.0006 19.3 0.1 0.0034 16.8 0.0 2.2 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 ORX84912.1 - 0.0037 17.3 0.6 13 5.9 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_7 PF13899.6 ORX84912.1 - 0.032 14.4 0.0 0.36 11.0 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin-like Thioredoxin_5 PF13743.6 ORX84912.1 - 0.036 13.8 0.2 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_8 PF13905.6 ORX84912.1 - 0.15 12.4 1.8 11 6.4 0.0 3.6 5 0 0 5 5 5 0 Thioredoxin-like DUF1510 PF07423.11 ORX84912.1 - 0.23 11.6 0.9 8.9 6.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) RHD3 PF05879.12 ORX84913.1 - 1.2e-232 774.3 16.8 4.6e-202 673.1 10.7 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 ORX84913.1 - 4.2e-05 23.7 0.0 4.2e-05 23.7 0.0 3.1 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORX84913.1 - 4.7e-05 23.4 4.1 7.4e-05 22.8 0.1 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase GBP PF02263.19 ORX84913.1 - 0.00036 19.9 5.1 0.00088 18.6 0.3 2.4 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain APOBEC4_like PF18774.1 ORX84913.1 - 0.04 13.8 0.3 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase AAA_28 PF13521.6 ORX84913.1 - 0.11 12.8 1.0 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORX84913.1 - 1.3 9.6 3.5 5.8 7.4 0.0 2.9 2 1 0 2 2 2 0 ABC transporter DUF4190 PF13828.6 ORX84914.1 - 0.086 12.6 0.1 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) CBM9_1 PF06452.11 ORX84915.1 - 3.1e-07 30.5 0.2 6.2e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like Tubulin PF00091.25 ORX84916.1 - 4.3e-72 242.5 0.0 8e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX84916.1 - 3.3e-42 143.6 0.1 5.2e-42 143.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX84916.1 - 5.2e-05 23.5 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORX84916.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORX84916.1 - 0.015 14.5 0.1 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Ldh_1_N PF00056.23 ORX84917.1 - 1.8e-34 118.8 0.6 2.6e-34 118.3 0.6 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX84917.1 - 2.7e-22 79.5 0.0 6.8e-22 78.2 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX84917.1 - 0.00053 19.7 0.5 0.0044 16.7 0.5 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORX84917.1 - 0.00095 19.1 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX84917.1 - 0.0013 19.0 0.4 0.0029 17.8 0.4 1.6 1 0 0 1 1 1 1 TrkA-N domain DAO PF01266.24 ORX84917.1 - 0.0028 17.3 1.2 0.012 15.2 0.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORX84917.1 - 0.01 15.5 1.8 0.097 12.2 1.8 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 ORX84917.1 - 0.01 16.4 0.3 0.027 15.1 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CdAMP_rec PF06153.11 ORX84917.1 - 0.026 14.7 0.1 0.06 13.5 0.1 1.6 1 0 0 1 1 1 0 Cyclic-di-AMP receptor AdoMet_dc PF02675.15 ORX84917.1 - 0.05 13.9 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase 2-Hacid_dh_C PF02826.19 ORX84917.1 - 0.089 12.2 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 ORX84917.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family HBS1_N PF08938.10 ORX84917.1 - 0.15 12.3 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus Cyclin PF08613.11 ORX84918.1 - 4.8e-37 127.8 0.0 9.2e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX84918.1 - 0.00048 19.9 0.1 0.0008 19.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Allantoicase PF03561.15 ORX84919.1 - 6.7e-41 139.6 0.1 5.7e-12 45.8 0.0 4.1 2 2 2 4 4 4 4 Allantoicase repeat Con-6 PF10346.9 ORX84921.1 - 2.1e-07 30.8 1.5 2.1e-07 30.8 1.5 2.1 2 0 0 2 2 2 1 Conidiation protein 6 Con-6 PF10346.9 ORX84922.1 - 4.2e-15 55.5 7.5 1.4e-07 31.4 0.7 2.5 2 0 0 2 2 2 2 Conidiation protein 6 DUF3933 PF13069.6 ORX84922.1 - 0.052 13.4 0.9 6 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) DUF1398 PF07166.11 ORX84922.1 - 0.34 11.0 1.8 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) Lactamase_B PF00753.27 ORX84923.1 - 7.4e-18 65.3 0.0 1.6e-17 64.2 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX84923.1 - 4.1e-05 23.2 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Enolase_C PF00113.22 ORX84974.1 - 9.5e-156 517.5 1.0 1.3e-155 517.0 0.2 1.5 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORX84974.1 - 8.3e-59 197.5 0.3 1.3e-58 196.8 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORX84974.1 - 1.4e-10 41.1 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORX84974.1 - 0.00049 19.3 0.4 0.001 18.3 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Peptidase_S10 PF00450.22 ORX84975.1 - 1.3e-126 423.4 0.7 1.6e-126 423.1 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Fasciclin PF02469.22 ORX84976.1 - 1.4e-36 125.5 0.3 8.6e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain HTH_39 PF14090.6 ORX84976.1 - 0.025 14.3 0.1 1.1 9.1 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain RasGAP PF00616.19 ORX84977.1 - 1.2e-30 106.7 0.3 8.2e-21 74.7 0.2 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase HEPN_RES_NTD1 PF18870.1 ORX84977.1 - 0.04 14.1 0.1 6.5 7.0 0.0 2.6 3 0 0 3 3 3 0 HEPN/RES N-terminal domain 1 C2 PF00168.30 ORX84977.1 - 0.048 13.9 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain DUF2358 PF10184.9 ORX84977.1 - 0.092 13.0 0.1 0.25 11.7 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) bVLRF1 PF18826.1 ORX84980.1 - 1e-55 187.7 0.2 1.9e-55 186.9 0.2 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 ORX84980.1 - 4.8e-08 32.7 0.8 4.8e-08 32.7 0.8 1.9 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_2 PF12796.7 ORX84980.1 - 0.016 15.7 0.0 0.057 14.0 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) CBP4 PF07960.11 ORX84980.1 - 0.063 13.1 8.3 2.9 7.8 0.1 2.9 2 0 0 2 2 2 0 CBP4 Ank PF00023.30 ORX84980.1 - 0.11 13.0 0.0 0.4 11.2 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat TRAM1 PF08390.11 ORX84981.1 - 0.084 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 TRAM1-like protein GATA PF00320.27 ORX84982.1 - 2.3e-15 55.9 7.3 4.3e-15 55.0 7.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORX84982.1 - 3.1e-13 49.8 0.0 6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORX84982.1 - 8.1e-12 45.1 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 ORX84982.1 - 2.3e-08 34.1 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 ORX84982.1 - 8.5e-07 29.2 0.0 2.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX84982.1 - 0.00023 21.4 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORX84982.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain AOX PF01786.17 ORX84983.1 - 1.1e-84 283.4 0.4 1.3e-84 283.1 0.4 1.0 1 0 0 1 1 1 1 Alternative oxidase MFS_1 PF07690.16 ORX85037.1 - 1.2e-52 179.0 45.6 1.2e-52 179.0 45.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX85037.1 - 4.3e-15 55.5 12.7 4.3e-15 55.5 12.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX85037.1 - 4.6e-15 55.1 22.3 8.2e-15 54.2 22.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Radical_SAM PF04055.21 ORX85038.1 - 6.2e-16 59.2 0.5 2.7e-15 57.1 0.2 2.3 2 1 0 2 2 2 1 Radical SAM superfamily Methyltransf_11 PF08241.12 ORX85039.1 - 1.4e-17 64.1 0.0 2.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX85039.1 - 1.4e-13 51.3 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX85039.1 - 2.9e-10 40.2 0.0 4.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX85039.1 - 4e-08 33.9 0.0 1.8e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX85039.1 - 5.9e-06 26.1 0.0 1.9e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX85039.1 - 0.00051 19.4 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORX85039.1 - 0.0026 17.6 0.0 0.02 14.7 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 ORX85039.1 - 0.0067 15.6 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase FliL PF03748.14 ORX85039.1 - 0.095 13.3 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL MTS PF05175.14 ORX85039.1 - 0.15 11.6 0.0 0.96 9.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 ORX85040.1 - 1.3e-17 64.2 0.0 2.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX85040.1 - 1.3e-13 51.5 0.0 2.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX85040.1 - 2.5e-10 40.4 0.0 3.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX85040.1 - 2.6e-08 34.5 0.0 1.6e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX85040.1 - 4.7e-06 26.5 0.0 1.6e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX85040.1 - 0.00045 19.6 0.0 0.00099 18.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORX85040.1 - 0.0022 17.9 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 ORX85040.1 - 0.0059 15.7 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 ORX85040.1 - 0.12 11.9 0.0 0.83 9.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 ORX85041.1 - 1.5e-54 185.1 0.0 9.7e-54 182.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX85041.1 - 7.5e-24 84.4 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX85041.1 - 1.9e-06 27.4 0.0 3.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX85041.1 - 6.7e-05 22.9 0.2 0.00044 20.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX85041.1 - 0.0033 17.1 1.4 0.027 14.1 0.1 2.4 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX85041.1 - 0.0086 15.1 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX85041.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORX85041.1 - 0.26 10.6 3.0 0.09 12.1 0.3 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORX85042.1 - 2.5e-47 161.5 0.0 3.7e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX85042.1 - 8.1e-21 74.5 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX85042.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORX85042.1 - 0.0015 18.5 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX85042.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX85042.1 - 0.055 12.4 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX85042.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Tex_YqgF PF16921.5 ORX85043.1 - 2.3e-49 167.0 0.0 5.9e-49 165.7 0.0 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain Tex_N PF09371.10 ORX85043.1 - 5.3e-44 150.1 3.1 1.3e-43 148.8 3.1 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 ORX85043.1 - 1.1e-27 96.1 0.0 6.3e-27 93.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_9 PF17674.1 ORX85043.1 - 7.3e-19 68.4 0.1 7.3e-19 68.4 0.1 3.4 4 0 0 4 4 3 1 HHH domain HHH_7 PF14635.6 ORX85043.1 - 2.7e-13 50.1 0.0 7.3e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 ORX85043.1 - 1.4e-10 41.4 0.0 2.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 ORX85043.1 - 8.9e-07 28.8 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_5 PF14520.6 ORX85043.1 - 0.0016 19.0 0.3 0.49 11.0 0.0 3.6 2 1 0 2 2 2 1 Helix-hairpin-helix domain HTH_44 PF14641.6 ORX85043.1 - 0.0081 16.6 0.1 0.018 15.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_6 PF14579.6 ORX85043.1 - 0.0088 16.3 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 ORX85043.1 - 0.019 14.8 0.0 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_2 PF12826.7 ORX85043.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif HSP20 PF00011.21 ORX85045.1 - 1.3e-15 57.3 0.0 2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORX85045.1 - 6.6e-08 32.0 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CBS PF00571.28 ORX85046.1 - 3.1e-31 107.6 5.9 1.1e-07 32.1 0.0 4.5 4 0 0 4 4 4 4 CBS domain GPAT_N PF14829.6 ORX85046.1 - 0.11 12.4 0.0 0.87 9.6 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal Pro_isomerase PF00160.21 ORX85047.1 - 8.1e-48 162.7 0.1 1.2e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORX85047.1 - 2.1e-19 69.1 0.0 3.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX85047.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX85047.1 - 0.04 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 ORX85047.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 LRR_6 PF13516.6 ORX85048.1 - 1.2e-11 43.7 0.9 0.00021 21.1 0.5 4.4 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.7 ORX85048.1 - 0.00013 21.8 0.7 0.00013 21.8 0.7 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORX85048.1 - 0.00089 19.6 3.0 3.1 8.3 0.0 4.0 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX85048.1 - 0.034 14.6 1.1 34 5.5 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat Recep_L_domain PF01030.24 ORX85048.1 - 0.044 13.9 0.0 0.54 10.4 0.0 2.6 1 1 1 2 2 2 0 Receptor L domain Ribonuclease_T2 PF00445.18 ORX85095.1 - 1.7e-05 25.2 0.0 1.7e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family GFO_IDH_MocA PF01408.22 ORX85096.1 - 4.5e-21 75.9 0.0 9.8e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORX85096.1 - 0.0041 17.8 0.2 0.008 16.8 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Plasmodium_HRP PF05403.11 ORX85098.1 - 1.3 8.8 33.8 0.032 14.0 24.1 2.6 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) XAP5 PF04921.14 ORX85146.1 - 4.9e-77 259.1 16.0 8.3e-77 258.4 15.9 1.5 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 ORX85146.1 - 3.6 8.0 21.0 0.25 11.7 11.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) CKAP2_C PF15297.6 ORX85147.1 - 0.0042 16.2 9.9 0.025 13.7 5.2 3.5 3 1 0 3 3 3 2 Cytoskeleton-associated protein 2 C-terminus EMP70 PF02990.16 ORX85148.1 - 2.6e-208 692.9 19.3 2.6e-208 692.9 19.3 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 ABC2_membrane PF01061.24 ORX85149.1 - 5e-43 147.0 23.9 5e-43 147.0 23.9 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORX85149.1 - 2e-10 41.3 0.1 4.5e-09 36.9 0.1 2.3 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX85149.1 - 2.5e-07 30.8 0.0 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 ORX85149.1 - 1.9e-05 24.5 0.9 1.9e-05 24.5 0.9 2.9 3 1 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORX85149.1 - 0.0033 16.6 22.9 0.0043 16.2 21.5 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 ORX85149.1 - 0.0051 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 ORX85149.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORX85149.1 - 0.026 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ORX85149.1 - 0.036 14.6 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX85149.1 - 0.04 14.3 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 ORX85149.1 - 0.078 11.6 0.0 0.72 8.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 ORX85149.1 - 0.12 11.1 5.0 0.21 10.3 5.0 1.3 1 0 0 1 1 1 0 Presenilin AAA_33 PF13671.6 ORX85149.1 - 0.16 12.2 0.2 0.47 10.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORX85149.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORX85149.1 - 0.17 11.3 0.0 5.9 6.3 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORX85149.1 - 0.19 12.0 0.0 0.44 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 ORX85149.1 - 0.85 8.8 6.7 1.4 8.2 4.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_18 PF00704.28 ORX85153.1 - 3.2e-77 260.3 4.8 3.2e-77 260.3 4.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX85153.1 - 0.023 15.3 7.3 0.023 15.3 7.3 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX85153.1 - 0.19 11.7 10.2 0.061 13.3 6.4 2.2 2 0 0 2 2 2 0 Cellulose-binding domain DUF3439 PF11921.8 ORX85153.1 - 1.3 9.0 8.3 2.5 8.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 ORX85154.1 - 2.9e-77 260.5 4.9 2.9e-77 260.5 4.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX85154.1 - 0.0056 17.2 2.6 0.0056 17.2 2.6 2.7 2 0 0 2 2 2 1 Carbohydrate binding domain DUF3439 PF11921.8 ORX85154.1 - 1.4 8.9 8.3 2.7 8.0 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 ORX85155.1 - 2.4e-77 260.8 4.9 2.4e-77 260.8 4.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX85155.1 - 0.042 14.5 7.1 0.042 14.5 7.1 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX85155.1 - 0.38 10.7 9.6 0.12 12.3 5.8 2.2 2 0 0 2 2 2 0 Cellulose-binding domain DUF3439 PF11921.8 ORX85155.1 - 1.3 9.0 8.4 2.6 8.0 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S9_N PF02897.15 ORX85156.1 - 2.2e-83 280.4 12.5 3.1e-83 279.9 12.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORX85156.1 - 6.8e-60 202.2 0.0 1.3e-59 201.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 ORX85156.1 - 0.0057 15.4 0.0 0.012 14.3 0.0 1.5 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 ORX85156.1 - 0.0066 16.4 0.2 0.24 11.4 0.1 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 ORX85156.1 - 0.17 11.7 0.0 0.56 10.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Skp1_POZ PF03931.15 ORX85157.1 - 1.2e-23 83.1 2.0 1.3e-23 82.9 0.3 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 ORX85157.1 - 1.1e-20 73.5 2.5 2.3e-20 72.4 2.5 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain DUF2004 PF09406.10 ORX85157.1 - 0.16 12.3 1.5 0.37 11.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2004) UBD PF16455.5 ORX85158.1 - 1.7e-32 111.7 0.0 2.5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 ORX85158.1 - 5.8e-06 26.0 0.0 9.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX85158.1 - 3.8e-05 23.4 0.0 5.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORX85158.1 - 0.0018 18.4 0.1 0.0032 17.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 ORX85158.1 - 0.0038 17.4 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain DUF2407 PF10302.9 ORX85158.1 - 0.012 16.2 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RPN2_C PF18004.1 ORX85159.1 - 3.5e-53 179.8 7.0 5.8e-53 179.1 7.0 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 ORX85159.1 - 1.8e-42 141.6 20.1 2.7e-08 33.8 0.0 8.3 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORX85159.1 - 5.3e-21 74.8 4.2 2.9e-14 53.2 0.0 5.5 4 1 2 7 7 7 3 HEAT repeats HEAT PF02985.22 ORX85159.1 - 6.5e-05 22.9 0.1 1.3 9.4 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 ORX85159.1 - 0.0001 22.7 0.8 0.21 12.1 0.0 3.8 2 1 2 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 ORX85159.1 - 0.016 15.3 1.0 6.3 6.8 0.0 3.9 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 ORX85159.1 - 0.038 14.6 2.6 31 5.7 0.0 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat TPR_19 PF14559.6 ORX85159.1 - 0.3 11.6 2.5 12 6.5 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Vfa1 PF08432.10 ORX85159.1 - 3.6 7.9 11.8 3.9 7.8 8.7 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.25 ORX85160.1 - 2.8e-29 102.3 0.0 3.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX85160.1 - 2.3e-13 50.0 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX85160.1 - 0.014 14.8 0.0 0.045 13.1 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 ORX85160.1 - 0.053 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORX85160.1 - 0.18 10.7 0.1 0.3 10.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.28 ORX85161.1 - 1.7e-101 339.9 0.0 2.2e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX85161.1 - 6e-13 49.6 1.0 1.7e-12 48.1 1.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BMC PF00936.19 ORX85161.1 - 0.0056 16.7 0.2 0.02 14.9 0.2 2.0 1 0 0 1 1 1 1 BMC domain MASE3 PF17159.4 ORX85161.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain SpecificRecomb PF10136.9 ORX85161.1 - 0.29 9.4 0.5 0.41 8.9 0.5 1.1 1 0 0 1 1 1 0 Site-specific recombinase Arv1 PF04161.13 ORX85162.1 - 2.9e-63 213.8 6.4 4.1e-63 213.3 6.4 1.2 1 0 0 1 1 1 1 Arv1-like family DZR PF12773.7 ORX85162.1 - 0.1 12.7 0.6 0.18 11.8 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Engrail_1_C_sig PF10525.9 ORX85162.1 - 0.46 9.7 2.0 0.99 8.7 2.0 1.4 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Ribosomal_L31e PF01198.19 ORX85163.1 - 2.7e-39 133.2 2.7 3.4e-39 133.0 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e zf-RING_2 PF13639.6 ORX85164.1 - 7.2e-12 45.4 6.4 1.7e-11 44.3 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORX85164.1 - 1.4e-09 37.5 4.6 3.2e-09 36.4 4.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORX85164.1 - 1.2e-07 31.5 4.8 2.8e-07 30.3 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX85164.1 - 1.6e-07 31.1 6.3 3.6e-07 29.9 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX85164.1 - 9.1e-07 29.1 7.6 4.3e-06 26.9 7.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORX85164.1 - 0.00099 19.0 6.9 0.002 18.0 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORX85164.1 - 0.0028 17.7 5.5 0.012 15.6 5.5 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger LRR19-TM PF15176.6 ORX85164.1 - 0.041 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain zf-RING_UBOX PF13445.6 ORX85164.1 - 0.045 13.8 7.6 0.053 13.6 5.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORX85164.1 - 0.12 12.0 4.5 0.28 10.8 4.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 ORX85164.1 - 0.14 12.5 3.7 0.29 11.5 3.7 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 ORX85164.1 - 0.31 10.9 8.1 0.58 10.0 8.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 ORX85164.1 - 0.54 10.2 7.8 1.3 9.0 7.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 ORX85164.1 - 1 9.3 7.8 2.5 8.1 7.8 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ORX85164.1 - 2.2 8.5 8.4 24 5.2 8.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 ORX85164.1 - 2.9 7.8 11.2 0.27 11.1 6.5 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 ORX85165.1 - 3.2e-41 141.0 0.2 4.8e-41 140.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX85165.1 - 1.1e-30 106.2 0.1 8.5e-30 103.4 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX85165.1 - 1.2e-08 35.2 0.0 3.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORX85165.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.14 ORX85165.1 - 0.027 12.8 1.7 0.035 12.4 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 ORX85165.1 - 0.15 10.9 3.7 0.22 10.3 3.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GEN1_C PF18380.1 ORX85165.1 - 6 7.8 8.1 20 6.1 8.1 1.9 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain YqfQ PF14181.6 ORX85165.1 - 8.5 6.5 8.3 20 5.3 8.3 1.6 1 0 0 1 1 1 0 YqfQ-like protein ApoO PF09769.9 ORX85166.1 - 2.3e-27 95.5 7.0 6.1e-26 90.9 0.2 2.8 1 1 1 2 2 2 1 Apolipoprotein O Apolipoprotein PF01442.18 ORX85166.1 - 0.0002 21.3 8.3 0.0071 16.2 6.5 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 ORX85166.1 - 0.0051 17.3 13.0 2.2 8.9 5.9 3.5 2 1 1 3 3 3 2 YtxH-like protein ApoLp-III PF07464.11 ORX85166.1 - 0.0056 16.8 17.7 0.012 15.7 12.3 2.7 2 1 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 ORX85166.1 - 0.0097 16.0 5.8 0.02 14.9 2.6 2.4 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 ORX85166.1 - 0.017 13.1 4.7 0.073 11.0 3.2 2.1 2 0 0 2 2 2 0 Prominin GldM_N PF12081.8 ORX85166.1 - 0.036 14.2 8.5 0.048 13.7 6.6 1.9 2 0 0 2 2 2 0 GldM N-terminal domain tRNA-synt_1e PF01406.19 ORX85166.1 - 0.05 12.9 0.9 0.078 12.3 0.9 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF445 PF04286.12 ORX85166.1 - 0.051 13.4 7.5 0.098 12.4 7.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ISG65-75 PF11727.8 ORX85166.1 - 0.12 11.6 10.5 0.023 13.9 7.1 1.4 2 0 0 2 2 2 0 Invariant surface glycoprotein Taxilin PF09728.9 ORX85166.1 - 0.15 11.2 7.4 0.047 12.9 4.6 1.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF883 PF05957.13 ORX85166.1 - 0.23 12.1 9.3 1.1 9.9 2.6 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Grg1 PF11034.8 ORX85166.1 - 0.28 11.4 20.0 0.14 12.4 2.7 3.5 4 0 0 4 4 3 0 Glucose-repressible protein Grg1 Syntaxin_2 PF14523.6 ORX85166.1 - 0.37 11.2 9.3 0.6 10.5 1.9 2.9 2 1 1 3 3 3 0 Syntaxin-like protein DUF5082 PF16888.5 ORX85166.1 - 0.41 10.9 8.2 0.18 12.1 3.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF948 PF06103.11 ORX85166.1 - 0.5 10.7 16.4 3.4 8.0 3.2 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SOAR PF16533.5 ORX85166.1 - 0.91 9.5 8.4 9 6.3 6.5 2.7 2 1 0 2 2 2 0 STIM1 Orai1-activating region EspB PF05802.11 ORX85166.1 - 1.3 8.9 15.3 0.42 10.6 11.8 1.9 2 1 0 2 2 2 0 Enterobacterial EspB protein ZYG-11_interact PF05884.12 ORX85166.1 - 1.8 7.9 4.9 3.6 6.9 4.1 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 AcylCoA_dehyd_C PF12186.8 ORX85166.1 - 2.2 8.4 5.9 25 5.1 0.9 3.0 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase C terminal DUF148 PF02520.17 ORX85166.1 - 2.7 8.1 10.8 18 5.5 6.7 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF148 TMPIT PF07851.13 ORX85166.1 - 3.4 6.8 5.3 4.4 6.4 4.7 1.4 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 ORX85166.1 - 3.5 7.7 13.2 1.6 8.8 8.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ParB PF08775.10 ORX85166.1 - 6.3 7.3 9.9 32 5.0 4.3 2.7 1 1 1 2 2 2 0 ParB family DSL PF01414.19 ORX85215.1 - 0.022 15.0 4.2 0.022 15.0 4.2 1.8 2 0 0 2 2 2 0 Delta serrate ligand Spidroin_MaSp PF11260.8 ORX85216.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 RRM_1 PF00076.22 ORX85217.1 - 1.9e-08 34.0 0.0 5.1e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX85217.1 - 0.024 14.7 0.0 0.081 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif DTW PF03942.15 ORX85218.1 - 4.5e-30 104.9 0.0 6.9e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 DTW domain C1_2 PF03107.16 ORX85218.1 - 0.16 12.3 3.9 0.3 11.4 3.9 1.4 1 0 0 1 1 1 0 C1 domain zf-C3HC4_3 PF13920.6 ORX85219.1 - 2.2e-08 33.8 12.8 9.7e-08 31.8 12.8 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-GRF PF06839.12 ORX85219.1 - 0.0019 18.2 5.4 0.0019 18.2 5.4 3.1 3 0 0 3 3 3 1 GRF zinc finger Prok-RING_4 PF14447.6 ORX85219.1 - 0.022 14.6 11.8 0.099 12.5 11.8 2.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 baeRF_family12 PF18856.1 ORX85219.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 CAP_N PF01213.19 ORX85220.1 - 6e-115 384.1 0.5 6e-115 384.1 0.5 1.3 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ORX85220.1 - 8.1e-51 171.7 11.6 5.9e-49 165.7 11.6 2.3 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PAR1 PF06521.11 ORX85220.1 - 0.0017 18.0 0.8 2.6 7.7 0.0 2.9 3 0 0 3 3 3 2 PAR1 protein TBCC PF07986.12 ORX85220.1 - 0.052 13.3 1.5 0.1 12.3 1.5 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C Ribosomal_S4e PF00900.20 ORX85221.1 - 2.7e-36 123.3 0.1 5.4e-36 122.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX85221.1 - 6.1e-27 93.0 0.1 1.1e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORX85221.1 - 2.8e-21 75.3 6.6 6.5e-21 74.2 6.6 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORX85221.1 - 2e-08 33.8 0.2 4.7e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORX85221.1 - 6.5e-05 22.7 8.0 7.2e-05 22.6 5.4 2.5 2 0 0 2 2 2 1 KOW motif Zds_C PF08632.10 ORX85222.1 - 1.3e-25 88.9 2.4 2.2e-25 88.2 2.4 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Arteri_nucleo PF01481.16 ORX85222.1 - 0.087 13.1 0.6 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein Ribosomal_S8e PF01201.22 ORX85223.1 - 1.1e-57 194.0 1.9 1.4e-57 193.7 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e AftA_C PF12249.8 ORX85223.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Clat_adaptor_s PF01217.20 ORX85224.1 - 1.3e-25 90.0 0.4 1.6e-25 89.7 0.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 ORX85224.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.4 2 0 0 2 2 2 1 AP-5 complex subunit sigma-1 Sda PF08970.10 ORX85224.1 - 0.059 13.1 1.3 0.3 10.8 0.0 2.6 2 1 0 2 2 2 0 Sporulation inhibitor A AAA_18 PF13238.6 ORX85224.1 - 0.15 12.6 0.0 0.48 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_trans_NIPA PF05653.14 ORX85280.1 - 1.8e-15 56.9 14.2 3e-09 36.4 7.4 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORX85280.1 - 0.11 12.6 26.1 0.67 10.1 6.7 2.8 2 1 0 2 2 2 0 EamA-like transporter family DUF2427 PF10348.9 ORX85280.1 - 4.2 7.2 9.0 0.58 10.0 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MS_channel PF00924.18 ORX85281.1 - 2e-25 89.6 2.4 4.7e-25 88.3 2.4 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2709 PF10915.8 ORX85281.1 - 0.0024 17.2 0.4 0.0048 16.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2709) JIP_LZII PF16471.5 ORX85281.1 - 0.019 15.1 0.2 0.019 15.1 0.2 2.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II FlgN PF05130.12 ORX85281.1 - 0.11 13.0 1.4 16 6.0 0.1 2.6 2 0 0 2 2 2 0 FlgN protein E1-E2_ATPase PF00122.20 ORX85281.1 - 4.8 6.7 8.1 1.4 8.4 0.8 2.4 2 0 0 2 2 2 0 E1-E2 ATPase EB1 PF03271.17 ORX85282.1 - 8.3e-09 35.6 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORX85282.1 - 5.7e-07 29.7 0.2 9.9e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain SlyX PF04102.12 ORX85282.1 - 0.03 14.9 0.5 0.07 13.8 0.5 1.5 1 0 0 1 1 1 0 SlyX CH_2 PF06294.11 ORX85282.1 - 0.033 14.3 0.2 0.057 13.5 0.2 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein TENA_THI-4 PF03070.16 ORX85282.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Suppressor_APC PF11414.8 ORX85282.1 - 0.1 12.7 1.6 0.19 11.8 0.8 1.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein PH PF00169.29 ORX85283.1 - 5.9e-11 42.8 0.2 1e-10 42.0 0.2 1.4 1 0 0 1 1 1 1 PH domain Nuc_sug_transp PF04142.15 ORX85284.1 - 5.3e-109 364.2 16.5 6e-109 364.0 16.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 ORX85284.1 - 5.7e-07 29.2 17.6 4.1e-05 23.1 10.1 2.2 1 1 1 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 ORX85284.1 - 9.2e-07 28.3 19.0 4e-06 26.2 18.9 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORX85284.1 - 7.5e-06 26.2 29.7 2.4e-05 24.5 5.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 ORX85284.1 - 2.4e-05 24.0 1.1 2.4e-05 24.0 1.1 2.2 1 1 0 2 2 2 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 ORX85284.1 - 0.00052 19.3 26.3 0.012 14.8 26.3 2.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 ORX85284.1 - 0.0013 17.8 6.3 0.0013 17.8 6.3 1.8 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DMT_6 PF04342.12 ORX85284.1 - 0.21 11.8 7.3 0.73 10.1 0.5 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) TMEM234 PF10639.9 ORX85284.1 - 0.74 9.9 7.0 0.68 10.0 1.1 2.5 2 1 0 2 2 2 0 Putative transmembrane family 234 OST3_OST6 PF04756.13 ORX85284.1 - 3 7.1 13.5 0.26 10.6 0.3 2.6 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family PTPA PF03095.15 ORX85285.1 - 2.6e-126 421.1 0.0 3e-126 420.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-H2C2_2 PF13465.6 ORX85286.1 - 3e-16 59.0 10.3 7.8e-09 35.6 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX85286.1 - 1.3e-14 53.7 17.8 3.8e-06 27.1 2.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX85286.1 - 6.7e-09 35.8 15.3 0.00087 19.9 1.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX85286.1 - 8.5e-07 29.1 1.9 0.59 10.5 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX85286.1 - 7.2e-06 25.9 9.8 0.077 13.0 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORX85286.1 - 0.00018 21.7 6.1 0.35 11.3 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX85286.1 - 0.00099 19.4 2.4 0.0027 18.0 2.4 1.6 1 1 0 1 1 1 1 C2H2-type zinc ribbon HypA PF01155.19 ORX85286.1 - 0.0011 18.9 0.6 0.0013 18.7 0.6 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 ORX85286.1 - 0.0015 18.7 9.1 0.17 12.1 2.6 3.0 1 1 1 2 2 2 2 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 ORX85286.1 - 0.0016 18.5 5.1 0.064 13.4 0.2 2.5 3 0 0 3 3 3 2 Zinc ribbon domain zf_UBZ PF18439.1 ORX85286.1 - 0.0047 16.5 4.2 0.18 11.4 0.2 3.0 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger DZR PF12773.7 ORX85286.1 - 0.0063 16.5 2.6 0.0083 16.1 2.6 1.4 1 1 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.22 ORX85286.1 - 0.0088 15.9 1.3 0.016 15.1 0.8 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 ORX85286.1 - 0.01 16.6 1.4 0.013 16.2 0.9 1.4 1 1 0 1 1 1 1 zinc-ribbon family zf-C2HC_2 PF13913.6 ORX85286.1 - 0.036 14.0 7.7 0.33 10.9 2.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORX85286.1 - 0.041 13.7 11.1 0.16 11.8 0.7 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_ZIC PF18366.1 ORX85286.1 - 0.043 13.9 5.4 1.5 9.0 0.5 2.8 2 1 1 3 3 3 0 Zic proteins zinc finger domain C1_4 PF07975.12 ORX85286.1 - 0.048 13.9 6.0 0.12 12.6 0.5 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Rpr2 PF04032.16 ORX85286.1 - 0.058 13.7 1.9 0.77 10.1 1.9 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_4 PF13717.6 ORX85286.1 - 0.073 13.0 2.0 5.7 7.0 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Sgf11 PF08209.11 ORX85286.1 - 0.085 12.4 3.5 0.31 10.6 0.4 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-CHY PF05495.12 ORX85286.1 - 0.11 13.0 5.6 0.24 11.9 5.6 1.7 1 1 0 1 1 1 0 CHY zinc finger XPA_N PF01286.18 ORX85286.1 - 0.11 12.5 2.3 10 6.3 0.0 2.8 3 0 0 3 3 3 0 XPA protein N-terminal ADK_lid PF05191.14 ORX85286.1 - 0.11 12.4 2.7 2.2 8.3 1.2 2.5 1 1 2 3 3 3 0 Adenylate kinase, active site lid zinc-ribbons_6 PF07191.12 ORX85286.1 - 0.12 12.4 4.6 0.41 10.7 2.4 2.3 1 1 1 2 2 2 0 zinc-ribbons zf-LYAR PF08790.11 ORX85286.1 - 0.12 12.3 6.8 0.98 9.4 0.7 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 ORX85286.1 - 0.21 11.4 0.2 0.21 11.4 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORX85286.1 - 0.22 12.0 8.8 2.8 8.5 2.6 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-UBP PF02148.19 ORX85286.1 - 0.36 11.2 4.5 0.16 12.3 2.2 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein IBR PF01485.21 ORX85286.1 - 0.41 10.9 6.7 0.18 12.1 1.2 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 ORX85286.1 - 0.42 10.6 4.0 1.7 8.7 0.4 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 ORX85286.1 - 1.2 8.9 12.2 0.82 9.4 1.5 2.5 3 0 0 3 3 2 0 Rubredoxin metal binding domain zf-BED PF02892.15 ORX85286.1 - 1.4 9.0 8.0 16 5.6 7.9 2.6 1 1 2 3 3 3 0 BED zinc finger ThiF PF00899.21 ORX85288.1 - 1.5e-18 67.0 0.0 2.2e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORX85288.1 - 4.1e-05 23.7 0.1 1.3 9.3 0.0 3.7 4 0 0 4 4 4 2 Ubiquitin-activating enzyme E1 four-helix bundle DUF2247 PF10004.9 ORX85288.1 - 0.0093 15.7 1.8 4 7.2 0.4 2.9 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2247) Ins_allergen_rp PF06757.13 ORX85288.1 - 0.063 13.2 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Zn_clus PF00172.18 ORX85290.1 - 1.3e-11 44.4 13.3 1.9e-11 43.9 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 ORX85291.1 - 1.8e-47 162.4 0.3 2.1e-47 162.2 0.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 ORX85291.1 - 1.2e-09 38.4 0.9 4e-06 27.0 0.2 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 ORX85291.1 - 3.3e-06 26.4 2.2 8.8e-06 25.0 2.2 2.0 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ABC2_membrane_3 PF12698.7 ORX85291.1 - 0.067 12.3 0.1 0.072 12.2 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Sec23_BS PF08033.12 ORX85291.1 - 0.17 12.6 0.5 0.51 11.1 0.5 1.7 1 1 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain QWRF PF04484.12 ORX85292.1 - 0.09 12.5 0.6 0.091 12.5 0.6 1.1 1 0 0 1 1 1 0 QWRF family MSP1_C PF07462.11 ORX85292.1 - 6.9 5.2 4.5 8.2 5.0 4.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ras PF00071.22 ORX85293.1 - 5.1e-60 201.8 0.7 6.6e-60 201.4 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX85293.1 - 1.1e-36 125.7 0.1 1.9e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX85293.1 - 2.9e-15 56.2 0.2 3.5e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX85293.1 - 2.3e-06 27.2 0.1 2.9e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORX85293.1 - 2.6e-06 27.1 0.2 1.8e-05 24.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX85293.1 - 3.7e-05 23.8 0.1 9.1e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX85293.1 - 0.00012 22.0 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 ORX85293.1 - 0.00016 21.1 0.2 0.0002 20.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 ORX85293.1 - 0.0026 17.6 0.1 0.009 15.8 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TetR_C_16 PF17920.1 ORX85293.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Peptidase_S8 PF00082.22 ORX85294.1 - 2.9e-40 138.4 9.6 4.9e-40 137.6 9.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX85294.1 - 1e-12 48.5 0.4 2.3e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 bZIP_2 PF07716.15 ORX85295.1 - 2.9e-08 33.6 10.5 8.7e-08 32.1 10.5 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX85295.1 - 7.8e-08 32.3 9.5 7.8e-08 32.3 9.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor KASH_CCD PF14662.6 ORX85295.1 - 0.0015 18.4 3.7 0.0039 17.0 3.7 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_Maf PF03131.17 ORX85295.1 - 0.03 14.8 9.2 0.079 13.5 9.2 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor TMCCDC2 PF15844.5 ORX85295.1 - 0.036 14.0 1.3 0.044 13.7 0.1 1.7 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 YabA PF06156.13 ORX85295.1 - 0.41 11.3 2.4 1.3 9.8 2.4 1.9 1 1 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 ORX85295.1 - 1.1 9.8 12.4 0.2 12.2 8.5 1.7 3 0 0 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 ORX85295.1 - 1.5 8.9 8.7 0.41 10.7 5.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Aldo_ket_red PF00248.21 ORX85296.1 - 8.6e-56 189.3 0.2 2.9e-54 184.3 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MinC_N PF05209.13 ORX85296.1 - 0.15 12.1 0.3 44 4.1 0.1 3.1 2 2 1 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain ABC_tran PF00005.27 ORX85297.1 - 4.4e-27 95.3 0.0 5.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX85297.1 - 2.3e-07 30.9 0.0 0.0046 16.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORX85297.1 - 0.00021 21.1 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ORX85297.1 - 0.00077 20.0 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORX85297.1 - 0.0019 17.7 0.0 0.33 10.4 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX85297.1 - 0.0019 17.9 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 ORX85297.1 - 0.0021 18.0 0.2 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORX85297.1 - 0.0038 17.6 0.0 0.0054 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 ORX85297.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORX85297.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 ORX85297.1 - 0.036 14.3 0.0 0.055 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORX85297.1 - 0.047 13.4 0.0 0.076 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORX85297.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ORX85297.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 ORX85297.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 ORX85297.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 ORX85297.1 - 0.19 11.8 0.0 0.45 10.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain PDT PF00800.18 ORX85298.1 - 1.5e-60 204.2 0.0 2.2e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 ORX85298.1 - 1.5e-16 60.5 0.0 2.5e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 ORX85298.1 - 2.9e-08 33.3 0.0 6.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain Arrestin_C PF02752.22 ORX85299.1 - 6.9e-11 42.7 0.0 5.5e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX85299.1 - 1.8e-06 28.1 0.0 5.7e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX85299.1 - 0.0033 17.1 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like DEAD PF00270.29 ORX85300.1 - 5.7e-43 146.7 0.0 1.4e-20 73.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX85300.1 - 1.1e-27 96.5 0.0 1.5e-26 92.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX85300.1 - 1.6e-06 28.3 0.0 3.2e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORX85300.1 - 0.00012 21.5 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SWI2_SNF2 PF18766.1 ORX85300.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UTP25 PF06862.12 ORX85300.1 - 0.083 11.6 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Nucleo_P87 PF07267.11 ORX85301.1 - 7.2 5.3 6.9 12 4.7 6.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_C50 PF03568.17 ORX85362.1 - 2.4e-26 92.8 0.2 8.5e-26 91.0 0.2 2.0 1 0 0 1 1 1 1 Peptidase family C50 TPR_2 PF07719.17 ORX85362.1 - 3.4e-10 39.2 15.6 0.0068 16.4 1.3 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORX85362.1 - 3.4e-09 36.1 11.3 0.00039 20.1 0.9 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX85362.1 - 3.7e-09 36.7 12.5 0.0015 18.8 3.4 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX85362.1 - 1.4e-07 31.1 12.8 0.051 13.8 0.8 7.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX85362.1 - 6.3e-05 22.7 1.9 0.91 9.7 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX85362.1 - 0.00062 19.2 5.4 0.0007 19.1 2.6 2.6 2 1 0 2 2 2 1 MalT-like TPR region SPO22 PF08631.10 ORX85362.1 - 0.0026 17.3 0.3 0.0026 17.3 0.3 2.6 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 ORX85362.1 - 0.0053 17.4 2.3 0.25 12.0 0.5 4.4 4 1 0 4 4 3 1 Tetratricopeptide repeat SNAP PF14938.6 ORX85362.1 - 0.0081 15.6 0.4 0.022 14.2 0.4 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 ORX85362.1 - 0.022 14.6 3.6 4.8 7.2 0.8 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Oxidoreduct_C PF16490.5 ORX85362.1 - 0.07 12.8 0.8 0.13 11.9 0.8 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain RNA_pol_Rbc25 PF08292.12 ORX85363.1 - 1.3e-39 135.4 0.0 2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 ORX85363.1 - 1.8e-18 66.6 0.1 3.4e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORX85363.1 - 0.0044 17.3 0.1 0.016 15.6 0.0 2.0 2 1 0 2 2 2 1 S1 RNA binding domain S1_2 PF13509.6 ORX85363.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 S1 domain AKAP7_NLS PF10469.9 ORX85364.1 - 6.8e-36 124.1 0.1 9.2e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 ORX85364.1 - 6.3e-16 58.0 0.1 1.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 KH domain SLS PF14611.6 ORX85364.1 - 0.0031 17.4 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 ORX85364.1 - 0.027 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 KH domain KH_4 PF13083.6 ORX85364.1 - 0.045 13.6 0.1 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 KH domain MIP PF00230.20 ORX85365.1 - 3.1e-58 197.2 10.2 3.8e-58 196.9 10.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 ORX85366.1 - 1e-57 195.5 6.5 1.3e-57 195.2 6.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein PAP2_C PF14360.6 ORX85367.1 - 4.5e-17 62.3 9.6 4.5e-17 62.3 9.6 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORX85367.1 - 1e-05 25.3 1.7 1e-05 25.3 1.7 1.8 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX85367.1 - 4.3 7.0 13.7 0.89 9.2 7.9 2.4 2 1 0 2 2 2 0 PAP2 superfamily Thioredoxin PF00085.20 ORX85368.1 - 5.9e-26 90.5 0.0 1.3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 ORX85368.1 - 5.3e-19 68.2 0.1 9.8e-19 67.4 0.1 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 ORX85368.1 - 8.6e-06 26.2 0.0 9.7e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORX85368.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 ORX85368.1 - 0.0023 18.2 0.0 0.01 16.2 0.0 2.0 2 2 1 3 3 3 1 Thioredoxin-like DIM1 PF02966.16 ORX85368.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 OST3_OST6 PF04756.13 ORX85368.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 ORX85368.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 ORX85368.1 - 0.061 13.1 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.10 ORX85368.1 - 0.097 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Redoxin RIH_assoc PF08454.11 ORX85369.1 - 1.5e-20 72.9 2.3 1.5e-20 72.9 2.3 4.9 6 0 0 6 6 6 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 ORX85369.1 - 3.1e-15 56.2 2.9 1.5e-08 34.3 0.1 4.1 4 0 0 4 4 4 2 RIH domain Ins145_P3_rec PF08709.11 ORX85369.1 - 3.6e-13 49.2 0.0 1e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 ORX85369.1 - 3.8e-12 46.0 8.4 1e-11 44.6 8.4 1.7 1 0 0 1 1 1 1 Ion transport protein MIR PF02815.19 ORX85369.1 - 1.6e-08 34.6 0.1 7.4e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 MIR domain Holin_BhlA PF10960.8 ORX85369.1 - 0.089 12.8 0.8 3.9 7.5 0.4 3.5 3 0 0 3 3 3 0 BhlA holin family DUF3361 PF11841.8 ORX85369.1 - 0.12 12.4 1.6 1.5 8.8 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) Tim17 PF02466.19 ORX85370.1 - 2.7e-11 43.8 0.9 5e-11 43.0 0.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pro_isomerase PF00160.21 ORX85371.1 - 8.2e-45 152.9 0.2 8.2e-45 152.9 0.2 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NmrA PF05368.13 ORX85372.1 - 7.4e-25 87.9 0.1 1.2e-24 87.1 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX85372.1 - 1.8e-17 63.8 0.1 2.5e-17 63.4 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX85372.1 - 3.5e-10 39.8 0.2 2.6e-08 33.6 0.1 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX85372.1 - 7.9e-06 25.1 0.2 1.3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX85372.1 - 0.0021 17.3 0.1 0.0061 15.8 0.1 1.6 1 1 1 2 2 2 1 Male sterility protein DapB_N PF01113.20 ORX85372.1 - 0.0026 17.9 0.2 0.0051 16.9 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 ORX85372.1 - 0.0035 16.8 0.2 0.0059 16.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KNTase_C PF07827.11 ORX85372.1 - 0.0051 16.6 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 1 KNTase C-terminal domain KR PF08659.10 ORX85372.1 - 0.0067 16.4 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ORX85372.1 - 0.024 15.1 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORX85372.1 - 0.091 12.1 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORX85372.1 - 0.13 11.4 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MAM33 PF02330.16 ORX85373.1 - 3.9e-63 213.2 5.6 4.4e-63 213.0 5.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein SelR PF01641.18 ORX85374.1 - 4.3e-51 172.1 0.0 5.2e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 ORX85374.1 - 0.004 17.1 0.4 0.81 9.8 0.0 2.3 2 0 0 2 2 2 2 Double zinc ribbon Yippee-Mis18 PF03226.14 ORX85374.1 - 0.049 13.9 0.6 0.14 12.4 0.6 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tnp_zf-ribbon_2 PF13842.6 ORX85374.1 - 0.051 14.4 0.2 1.2 10.0 0.0 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon B12D PF06522.11 ORX85374.1 - 0.052 13.3 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zinc_ribbon_10 PF10058.9 ORX85374.1 - 0.056 13.2 0.3 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF678 PF05077.12 ORX85374.1 - 0.16 12.1 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) PAPS_reduct PF01507.19 ORX85375.1 - 8.6e-43 146.4 0.0 1.1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 ORX85376.1 - 6.5e-14 51.5 0.1 1e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 ORX85376.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) SPRY PF00622.28 ORX85377.1 - 5.3e-23 81.4 0.1 1.1e-22 80.4 0.1 1.5 1 0 0 1 1 1 1 SPRY domain ArfGap PF01412.18 ORX85379.1 - 1e-28 99.7 0.0 2.3e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 ORX85379.1 - 0.023 14.2 0.5 0.043 13.3 0.5 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zf-B_box PF00643.24 ORX85379.1 - 0.041 14.0 0.5 0.063 13.4 0.5 1.3 1 0 0 1 1 1 0 B-box zinc finger CHCH PF06747.13 ORX85380.1 - 4.6e-08 33.0 4.7 6.2e-08 32.6 4.7 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 ORX85380.1 - 0.00014 21.5 1.1 0.00017 21.2 1.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 ORX85380.1 - 0.00056 20.2 3.2 0.0014 18.9 3.2 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 ORX85380.1 - 0.0034 17.4 1.8 0.0051 16.8 1.8 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 ORX85380.1 - 0.009 16.0 3.8 0.012 15.6 3.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 ORX85380.1 - 0.012 15.8 0.7 0.017 15.4 0.7 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 ORX85380.1 - 0.028 14.8 2.6 0.054 13.9 2.3 1.5 1 1 1 2 2 2 0 GCK domain UPF0203 PF05254.12 ORX85380.1 - 0.41 10.9 3.1 2.4 8.4 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) PigN PF04987.14 ORX85434.1 - 3.6e-142 474.4 31.3 4.7e-142 474.1 31.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 ORX85434.1 - 4.5e-12 46.2 2.6 3.4e-10 40.1 2.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORX85434.1 - 1.6e-08 34.4 0.2 2.3e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ORX85434.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily RNase_T PF00929.24 ORX85435.1 - 2.3e-18 67.3 0.1 3.2e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORX85435.1 - 0.00095 18.9 0.3 0.0066 16.2 0.2 2.2 1 1 1 2 2 2 1 3'-5' exonuclease CAF1 PF04857.20 ORX85435.1 - 0.074 12.2 0.1 0.15 11.2 0.1 1.7 1 1 0 1 1 1 0 CAF1 family ribonuclease Pribosyltran PF00156.27 ORX85436.1 - 5.8e-24 84.4 0.0 7.7e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ORX85436.1 - 0.0035 16.9 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.6 ORX85436.1 - 0.045 13.2 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase NAD_kinase PF01513.21 ORX85437.1 - 2.5e-62 210.7 0.0 4.1e-62 210.0 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ORX85437.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain BTB_2 PF02214.22 ORX85438.1 - 2e-14 53.7 0.0 4.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 ORX85438.1 - 0.0025 17.9 0.0 0.0048 17.0 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Xan_ur_permease PF00860.20 ORX85439.1 - 6.3e-84 281.9 43.0 7.6e-84 281.7 43.0 1.1 1 0 0 1 1 1 1 Permease family ALMT PF11744.8 ORX85439.1 - 0.55 9.0 4.6 0.86 8.4 4.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter p450 PF00067.22 ORX85440.1 - 1.1e-48 166.2 0.0 2.2e-34 119.0 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 MAS20 PF02064.15 ORX85440.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Acetyltransf_7 PF13508.7 ORX85441.1 - 2.7e-11 43.7 0.0 4.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX85441.1 - 3.3e-11 43.4 0.0 4.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX85441.1 - 1.8e-09 37.6 0.1 2.6e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX85441.1 - 4.9e-06 26.6 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORX85441.1 - 2.2e-05 24.3 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 ORX85441.1 - 9.1e-05 22.0 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 ORX85441.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORX85441.1 - 0.13 12.9 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 ORX85442.1 - 1.1e-52 176.0 0.5 1.3e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NqrM PF04400.13 ORX85442.1 - 0.015 15.0 0.2 0.5 10.2 0.1 2.4 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM Ribonuclease_T2 PF00445.18 ORX85443.1 - 1.4e-36 126.4 1.7 1.9e-36 126.0 1.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family PGM_PMM_I PF02878.16 ORX85444.1 - 2.2e-41 140.8 0.0 6.8e-41 139.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ORX85444.1 - 6.4e-26 91.0 0.0 1.6e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ORX85444.1 - 1.9e-14 53.8 0.1 3.3e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ORX85444.1 - 1.4e-05 25.1 0.0 3.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AlphaC_C PF17480.2 ORX85444.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AlphaC C-terminal CDK5_activator PF03261.15 ORX85444.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DNA_pol_A_exo1 PF01612.20 ORX85445.1 - 1.6e-24 86.6 0.0 2.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Mut7-C PF01927.16 ORX85445.1 - 2.1e-21 76.6 1.6 3.2e-21 76.0 0.2 2.1 2 0 0 2 2 2 1 Mut7-C RNAse domain zf-RING_2 PF13639.6 ORX85446.1 - 1.1e-12 48.1 6.1 1.1e-12 48.1 6.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 ORX85446.1 - 6.4e-08 32.2 4.6 6.4e-08 32.2 4.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX85446.1 - 1.2e-07 31.4 9.3 1.4e-07 31.2 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX85446.1 - 4.2e-06 26.5 5.3 4.2e-06 26.5 5.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX85446.1 - 6.6e-06 26.3 9.0 1.7e-05 25.0 9.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORX85446.1 - 0.00016 21.6 4.5 0.001 19.0 3.4 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORX85446.1 - 0.0012 18.6 2.8 0.0012 18.6 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX85446.1 - 0.0039 17.1 4.0 0.0039 17.1 4.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain DUF962 PF06127.11 ORX85446.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF962) zf-ANAPC11 PF12861.7 ORX85446.1 - 0.053 13.6 5.1 0.17 12.0 5.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 ORX85446.1 - 0.08 13.1 5.5 0.15 12.2 5.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 ORX85446.1 - 0.092 12.9 6.7 0.42 10.8 6.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain HlyIII PF03006.20 ORX85446.1 - 0.14 11.8 11.0 0.97 9.1 4.7 2.1 1 1 1 2 2 2 0 Haemolysin-III related DUF1129 PF06570.11 ORX85446.1 - 0.19 11.2 1.2 0.22 11.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) COX15-CtaA PF02628.15 ORX85446.1 - 0.21 10.6 3.5 0.69 8.9 0.5 2.1 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein PHD PF00628.29 ORX85446.1 - 0.4 10.6 5.9 0.99 9.4 5.9 1.7 1 1 0 1 1 1 0 PHD-finger DUF1430 PF07242.11 ORX85446.1 - 0.98 9.7 5.7 0.84 9.9 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Zn_ribbon_17 PF17120.5 ORX85446.1 - 0.98 9.1 4.8 2.5 7.8 4.8 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2070 PF09843.9 ORX85446.1 - 2.4 6.4 5.9 3.5 5.8 5.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) p450 PF00067.22 ORX85448.1 - 1.3e-94 317.6 0.0 2.2e-94 316.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORX85448.1 - 5.4e-29 101.4 0.0 1e-27 97.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX85448.1 - 4.1e-24 85.4 0.1 5.2e-17 62.4 0.1 2.7 2 0 0 2 2 2 2 Flavodoxin NAD_binding_1 PF00175.21 ORX85448.1 - 3e-16 60.0 0.0 7.8e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 ORX85448.1 - 0.018 15.2 0.0 0.072 13.3 0.0 2.0 2 0 0 2 2 2 0 NrdI Flavodoxin like FAD_binding_3 PF01494.19 ORX85485.1 - 6.9e-26 91.3 0.0 3.5e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 ORX85485.1 - 7.7e-08 32.0 1.3 0.0005 19.5 0.0 3.6 3 1 0 4 4 4 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORX85485.1 - 1.3e-05 25.3 0.4 4e-05 23.7 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX85485.1 - 7.9e-05 22.1 0.1 0.0042 16.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX85485.1 - 0.0001 21.5 0.5 0.0004 19.6 0.1 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORX85485.1 - 0.0002 21.8 0.1 0.045 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX85485.1 - 0.0012 18.1 0.4 0.0054 16.0 0.4 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORX85485.1 - 0.0024 17.0 0.0 0.065 12.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 ORX85485.1 - 0.0065 15.6 0.4 0.012 14.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain RRM_1 PF00076.22 ORX85486.1 - 5.2e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 ORX85486.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 R3H domain SUZ-C PF12901.7 ORX85486.1 - 0.091 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 SUZ-C motif EnY2 PF10163.9 ORX85487.1 - 1.8e-25 89.1 0.2 2.2e-25 88.8 0.2 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Ras PF00071.22 ORX85488.1 - 8.3e-62 207.6 0.1 9.9e-62 207.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX85488.1 - 2.7e-33 114.7 0.1 7.6e-33 113.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX85488.1 - 4.7e-14 52.2 0.0 5.7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX85488.1 - 1.3e-05 25.3 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORX85488.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX85488.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX85488.1 - 0.0018 18.2 0.1 0.44 10.4 0.0 2.6 1 1 2 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ORX85488.1 - 0.0018 18.5 0.0 0.025 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 ORX85488.1 - 0.0055 16.3 0.1 0.032 13.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TetR_C_16 PF17920.1 ORX85488.1 - 0.06 13.6 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DAP3 PF10236.9 ORX85488.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 ORX85488.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_L14 PF00238.19 ORX85489.1 - 3.3e-35 120.8 0.1 4e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L27e PF01777.18 ORX85490.1 - 1.7e-36 124.4 7.7 1.7e-36 124.4 7.7 1.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 ORX85490.1 - 0.00014 21.7 1.4 0.00032 20.6 1.4 1.6 1 0 0 1 1 1 1 KOW motif AAA PF00004.29 ORX85491.1 - 6.1e-42 143.2 0.0 1.3e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX85491.1 - 1.3e-08 34.5 0.0 3.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORX85491.1 - 2.5e-05 24.3 0.0 9.3e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX85491.1 - 5e-05 23.6 0.1 0.0053 17.0 0.0 2.9 3 1 1 4 4 3 1 AAA domain AAA_2 PF07724.14 ORX85491.1 - 5.6e-05 23.3 0.0 0.00082 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORX85491.1 - 0.00011 22.6 0.1 0.0021 18.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORX85491.1 - 0.00043 19.5 0.0 0.00082 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORX85491.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ORX85491.1 - 0.01 15.3 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 ORX85491.1 - 0.012 15.6 0.7 6.1 6.7 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 ORX85491.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX85491.1 - 0.017 15.3 0.1 0.04 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 ORX85491.1 - 0.027 13.7 0.0 0.093 11.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 ORX85491.1 - 0.03 14.1 0.1 0.12 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 ORX85491.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORX85491.1 - 0.038 14.4 0.0 0.096 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 ORX85491.1 - 0.052 14.1 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORX85491.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 ORX85491.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IPT PF01745.16 ORX85491.1 - 0.073 12.4 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase ATPase PF06745.13 ORX85491.1 - 0.077 12.3 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 ORX85491.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 ORX85491.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORX85491.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Rrp15p PF07890.12 ORX85492.1 - 7.6e-30 104.0 12.2 7.6e-30 104.0 12.2 1.6 2 0 0 2 2 2 1 Rrp15p DUF5577 PF17740.1 ORX85492.1 - 0.28 10.8 7.7 0.26 10.9 6.9 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5577) DHHC PF01529.20 ORX85493.1 - 9e-37 126.2 11.5 1.2e-36 125.7 11.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF3899 PF13038.6 ORX85493.1 - 0.026 15.0 0.2 0.026 15.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) ABA_GPCR PF12430.8 ORX85494.1 - 2e-44 151.5 12.4 2e-44 151.5 12.4 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 ORX85494.1 - 2.5e-25 88.3 0.1 6.7e-25 87.0 0.1 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF1604 PF07713.13 ORX85494.1 - 0.041 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) CENP-F_leu_zip PF10473.9 ORX85494.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3671 PF12420.8 ORX85494.1 - 4 7.6 12.8 0.068 13.3 1.6 3.4 4 1 1 5 5 5 0 Protein of unknown function NPCC PF08058.11 ORX85494.1 - 6.7 6.8 8.5 1.6 8.8 0.0 3.0 3 1 0 3 3 3 0 Nuclear pore complex component ATP-grasp PF02222.22 ORX85495.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Pkinase PF00069.25 ORX85496.1 - 4.7e-74 249.1 0.0 5.8e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX85496.1 - 4.1e-32 111.5 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX85496.1 - 4.9e-07 29.3 0.0 3.9e-06 26.4 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 ORX85496.1 - 9.9e-06 24.6 0.1 7.5e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORX85496.1 - 0.00019 20.9 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX85496.1 - 0.0012 18.8 0.0 0.0086 16.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family bZIP_2 PF07716.15 ORX85497.1 - 1.3e-07 31.6 11.1 2.4e-07 30.7 11.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX85497.1 - 1.8e-06 27.9 12.0 3.5e-06 27.0 12.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX85497.1 - 4.4e-05 23.9 11.4 9.8e-05 22.8 11.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor FA_desaturase PF00487.24 ORX85498.1 - 6.3e-19 68.8 17.5 9.5e-19 68.2 17.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORX85498.1 - 3e-15 56.1 0.1 7.4e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIF PF03031.18 ORX85499.1 - 2.1e-24 86.1 0.0 2.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Cu-oxidase PF00394.22 ORX85500.1 - 2.7e-40 138.1 0.0 9.1e-37 126.6 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX85500.1 - 3.7e-36 123.7 0.1 7.4e-33 113.1 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX85500.1 - 1.9e-31 108.6 1.1 4.1e-27 94.6 0.1 3.7 3 2 0 3 3 3 2 Multicopper oxidase Methyltransf_23 PF13489.6 ORX85501.1 - 0.00014 21.7 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX85501.1 - 0.00027 21.6 0.0 0.0004 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX85501.1 - 0.0028 18.3 0.0 0.0074 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ORX85501.1 - 0.014 15.1 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 ORX85501.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 ORX85501.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.11 ORX85501.1 - 0.088 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) DnaJ PF00226.31 ORX85502.1 - 5.6e-21 74.4 0.4 9.9e-21 73.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain RNR_Alpha PF17975.1 ORX85503.1 - 1.2e-40 138.0 0.2 3.1e-40 136.7 0.2 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 ORX85503.1 - 1.2e-09 37.3 0.0 0.014 14.0 0.0 3.2 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain DUF2937 PF11157.8 ORX85504.1 - 0.05 13.3 1.0 0.075 12.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Barttin PF15462.6 ORX85504.1 - 0.36 10.6 4.0 0.44 10.3 4.0 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-AN1 PF01428.16 ORX85505.1 - 2.8e-21 75.4 37.5 5.3e-12 45.7 13.2 2.5 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX85505.1 - 0.0017 18.7 17.3 0.02 15.2 6.0 2.5 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain BUD22 PF09073.10 ORX85506.1 - 0.0042 16.5 2.5 0.0042 16.5 2.5 1.1 1 0 0 1 1 1 1 BUD22 Macoilin PF09726.9 ORX85506.1 - 0.034 12.7 10.8 0.04 12.5 10.8 1.1 1 0 0 1 1 1 0 Macoilin family VDE PF07137.11 ORX85506.1 - 0.045 13.3 6.2 0.057 12.9 6.2 1.1 1 0 0 1 1 1 0 VDE lipocalin domain Menin PF05053.13 ORX85506.1 - 0.14 10.5 5.1 0.15 10.4 5.1 1.2 1 0 0 1 1 1 0 Menin PI3K_1B_p101 PF10486.9 ORX85506.1 - 0.28 8.9 7.7 0.28 8.9 7.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peroxin-3 PF04882.12 ORX85506.1 - 0.9 8.5 5.1 1 8.3 5.1 1.1 1 0 0 1 1 1 0 Peroxin-3 Apt1 PF10351.9 ORX85506.1 - 3.9 6.2 9.5 4.9 5.9 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HNF-1_N PF04814.13 ORX85506.1 - 5.7 7.5 9.4 0.86 10.2 5.3 1.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CBM_5_12 PF02839.14 ORX85507.1 - 3.5e-05 24.1 8.6 3.5e-05 24.1 8.6 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX85507.1 - 8.1e-05 22.5 5.8 0.0001 22.1 5.8 1.2 1 0 0 1 1 1 1 Cellulose-binding domain Glyco_hydro_18 PF00704.28 ORX85508.1 - 1e-58 199.5 1.1 1.2e-58 199.3 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Plasmod_Pvs28 PF06247.11 ORX85509.1 - 3.8 7.9 6.2 35 4.8 0.1 3.4 3 1 1 4 4 4 0 Pvs28 EGF domain Mito_carr PF00153.27 ORX85571.1 - 4e-69 228.6 0.1 3.3e-27 94.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5518 PF17647.1 ORX85571.1 - 0.049 13.8 1.6 8.7 6.5 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Acetyltransf_1 PF00583.25 ORX85572.1 - 0.0023 18.2 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 ORX85572.1 - 0.049 13.8 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ArAE_2_N PF10337.9 ORX85572.1 - 0.28 10.2 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Tudor_3 PF18115.1 ORX85573.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 ORX85573.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain JmjC PF02373.22 ORX85574.1 - 1.5e-06 28.6 0.1 3.4e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase 4HBT PF03061.22 ORX85575.1 - 1.6e-10 41.2 0.0 3.3e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 ORX85575.1 - 0.0064 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Opi1 PF08618.10 ORX85576.1 - 6.8e-78 262.8 13.4 4.4e-45 154.7 1.0 3.8 2 1 2 4 4 4 3 Transcription factor Opi1 Perilipin PF03036.16 ORX85576.1 - 1.8e-09 37.1 0.0 1.8e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Perilipin family REF PF05755.12 ORX85576.1 - 8.3e-06 25.8 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) p31comet PF06581.12 ORX85576.1 - 0.0023 17.1 0.0 0.0059 15.8 0.0 1.4 1 1 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding Pex14_N PF04695.13 ORX85576.1 - 0.046 14.4 0.6 0.046 14.4 0.6 2.5 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CN_hydrolase PF00795.22 ORX85577.1 - 2.8e-37 128.5 0.0 5.8e-37 127.4 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase HEAT PF02985.22 ORX85620.1 - 3e-18 64.3 8.7 0.00077 19.5 0.1 10.3 12 0 0 12 12 9 3 HEAT repeat HEAT_EZ PF13513.6 ORX85620.1 - 5.7e-16 58.6 6.6 1.3e-08 35.2 0.3 7.6 6 3 3 9 9 9 2 HEAT-like repeat IBN_N PF03810.19 ORX85620.1 - 1.8e-13 50.2 4.1 2.7e-11 43.2 0.5 4.4 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 ORX85620.1 - 1.3e-10 41.5 6.7 0.078 13.4 0.0 6.7 3 2 4 7 7 7 4 HEAT repeats IFRD PF05004.13 ORX85620.1 - 1.2e-07 31.2 6.9 1 8.4 0.0 5.4 3 2 1 5 5 5 4 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 ORX85620.1 - 4.5e-07 29.9 7.7 0.011 15.6 0.1 6.0 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 ORX85620.1 - 1.6e-06 27.9 1.5 0.82 9.2 0.2 5.0 3 2 1 5 5 5 3 CLASP N terminal Arm PF00514.23 ORX85620.1 - 1.6e-05 24.8 11.2 0.035 14.2 0.1 6.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 ORX85620.1 - 3.7e-05 23.6 11.8 0.081 12.7 0.1 5.4 4 2 2 6 6 6 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 ORX85620.1 - 4.2e-05 24.1 1.6 0.15 12.7 0.1 5.6 6 2 0 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 ORX85620.1 - 0.00051 19.7 0.2 5.2 6.6 0.0 4.1 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II TIP120 PF08623.10 ORX85620.1 - 0.00086 19.1 1.9 0.46 10.2 0.0 4.1 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) Mer2 PF09074.10 ORX85620.1 - 0.0098 15.7 1.1 0.029 14.2 1.1 1.8 1 0 0 1 1 1 1 Mer2 TrpP PF17099.5 ORX85620.1 - 0.028 14.2 0.0 0.36 10.6 0.0 2.8 3 0 0 3 3 3 0 Tryptophan transporter TrpP TAF6_C PF07571.13 ORX85620.1 - 0.098 13.0 0.1 2.4 8.6 0.1 3.4 2 2 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain TACC_C PF05010.14 ORX85621.1 - 2.9e-08 33.7 24.2 2.9e-08 33.7 24.2 2.1 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HALZ PF02183.18 ORX85621.1 - 0.019 15.1 1.2 0.019 15.1 1.2 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper Tup_N PF08581.10 ORX85621.1 - 0.82 10.0 37.6 0.94 9.8 1.0 5.0 2 1 2 4 4 4 0 Tup N-terminal MetOD2 PF18548.1 ORX85621.1 - 1.6 8.9 16.0 0.92 9.7 0.2 4.1 3 2 2 5 5 5 0 Metanogen output domain 2 DUF948 PF06103.11 ORX85621.1 - 1.8 8.9 4.3 0.85 9.9 0.5 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 ORX85621.1 - 2 8.9 33.0 1.4 9.3 19.7 2.5 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 ORX85621.1 - 3.5 7.9 38.0 2.1 8.6 11.1 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 ORX85621.1 - 4.7 6.5 35.5 0.022 14.1 14.0 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ACPS PF01648.20 ORX85622.1 - 1.9e-17 63.4 0.4 6.2e-17 61.8 0.1 1.9 2 1 1 3 3 3 1 4'-phosphopantetheinyl transferase superfamily Ribophorin_I PF04597.14 ORX85623.1 - 7.3e-142 473.6 6.2 8.4e-142 473.4 6.2 1.0 1 0 0 1 1 1 1 Ribophorin I Peptidase_M41 PF01434.18 ORX85624.1 - 5.4e-65 218.8 3.7 1.4e-64 217.4 3.7 1.8 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORX85624.1 - 4.4e-43 146.9 0.0 1.4e-42 145.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX85624.1 - 2.7e-12 46.3 0.0 7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 ORX85624.1 - 1.6e-05 24.3 0.2 3.3e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ORX85624.1 - 1.9e-05 24.7 0.0 5.8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX85624.1 - 3.2e-05 24.4 0.4 0.00061 20.2 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORX85624.1 - 0.00011 22.0 0.1 0.00061 19.6 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX85624.1 - 0.00014 22.1 0.0 0.048 13.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.14 ORX85624.1 - 0.0023 18.0 0.0 0.016 15.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORX85624.1 - 0.009 16.6 0.0 0.051 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORX85624.1 - 0.0093 16.2 0.5 0.072 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORX85624.1 - 0.014 15.2 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 ORX85624.1 - 0.018 14.4 1.0 0.43 9.9 0.2 3.0 2 1 0 2 2 2 0 KaiC AAA_33 PF13671.6 ORX85624.1 - 0.024 14.8 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORX85624.1 - 0.029 13.8 0.2 0.07 12.5 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORX85624.1 - 0.053 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 ORX85624.1 - 0.056 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ORX85624.1 - 0.058 13.0 0.8 0.55 9.8 0.4 2.3 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 ORX85624.1 - 0.075 13.1 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Erp_C PF06780.11 ORX85624.1 - 0.079 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Erp protein C-terminus FtsA PF14450.6 ORX85624.1 - 0.093 13.2 0.2 0.3 11.5 0.2 1.8 1 0 0 1 1 1 0 Cell division protein FtsA PhoH PF02562.16 ORX85624.1 - 0.64 9.4 3.3 0.61 9.5 0.3 2.3 3 0 0 3 3 3 0 PhoH-like protein Methyltransf_12 PF08242.12 ORX85625.1 - 5e-15 56.1 0.2 3.2e-14 53.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX85625.1 - 1.3e-14 54.3 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX85625.1 - 3.7e-13 50.0 0.0 7.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX85625.1 - 4.6e-10 40.0 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX85625.1 - 4.4e-07 29.8 0.0 1.3e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 ORX85625.1 - 0.00012 21.8 0.0 0.00061 19.5 0.0 2.2 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 ORX85625.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 ORX85625.1 - 0.0031 17.3 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 ORX85625.1 - 0.016 14.7 0.0 5 6.5 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF3419 PF11899.8 ORX85625.1 - 0.018 14.3 0.1 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) AdoMet_MTase PF07757.13 ORX85625.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 ORX85625.1 - 0.088 12.2 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CH PF00307.31 ORX85626.1 - 2.2e-48 162.9 0.6 6.1e-25 87.5 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 ORX85626.1 - 2.9e-16 59.3 0.1 1.1e-15 57.5 0.1 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 ORX85626.1 - 4.4e-13 48.9 0.1 1e-08 34.9 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 ORX85626.1 - 2.2e-05 24.0 1.5 0.00018 21.2 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 ORX85626.1 - 4.2e-05 22.8 0.6 0.0043 16.5 0.1 2.9 2 0 0 2 2 2 1 EF hand Spectrin PF00435.21 ORX85626.1 - 0.0001 22.8 5.6 0.017 15.6 0.5 2.7 2 0 0 2 2 2 2 Spectrin repeat EF-hand_7 PF13499.6 ORX85626.1 - 0.0038 17.6 0.3 0.049 14.1 0.3 2.9 3 0 0 3 3 3 1 EF-hand domain pair Laminin_II PF06009.12 ORX85626.1 - 0.0064 16.5 2.4 0.027 14.5 0.9 2.5 2 0 0 2 2 2 1 Laminin Domain II DUF1664 PF07889.12 ORX85626.1 - 0.018 15.1 1.8 0.03 14.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORX85626.1 - 0.26 11.5 2.4 0.33 11.2 0.2 2.3 3 0 0 3 3 1 0 Bacterial protein of unknown function (DUF948) EF-hand_14 PF17959.1 ORX85626.1 - 0.28 11.5 1.4 2.4 8.6 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain NPV_P10 PF05531.12 ORX85626.1 - 0.95 10.0 5.3 4.5 7.8 2.4 3.3 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 ORX85626.1 - 1.2 9.2 10.9 0.23 11.5 5.1 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 ORX85626.1 - 6.7 4.8 10.0 2.4 6.2 6.4 1.9 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil ASPRs PF17641.2 ORX85627.1 - 0.098 12.9 0.1 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Nuc_sug_transp PF04142.15 ORX85628.1 - 2e-120 401.7 15.8 2.4e-120 401.4 15.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ORX85628.1 - 1.3e-08 35.1 31.0 7.4e-05 22.9 9.5 2.7 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 ORX85628.1 - 2.4e-06 27.0 16.9 4.9e-06 26.0 16.8 1.5 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 ORX85628.1 - 0.00054 19.6 1.8 0.00054 19.6 1.8 2.0 2 0 0 2 2 2 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 ORX85628.1 - 0.00071 18.9 18.9 0.0017 17.7 19.0 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Multi_Drug_Res PF00893.19 ORX85628.1 - 0.44 11.3 8.1 0.42 11.3 0.9 3.0 2 0 0 2 2 2 0 Small Multidrug Resistance protein TMEM234 PF10639.9 ORX85628.1 - 1 9.4 7.9 0.32 11.1 1.5 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 GARS_A PF01071.19 ORX85629.1 - 2.9e-84 281.7 0.1 4.9e-84 280.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 ORX85629.1 - 9.4e-38 129.8 0.0 2.1e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 ORX85629.1 - 2.9e-35 120.9 0.5 8.9e-35 119.4 0.1 2.1 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ORX85629.1 - 4.5e-28 97.4 0.2 1e-27 96.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 ORX85629.1 - 2.1e-15 57.1 2.2 5.8e-14 52.5 1.9 2.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 ORX85629.1 - 7.9e-07 29.3 0.0 2.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 ORX85629.1 - 8.6e-07 28.7 0.1 1.8e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ORX85629.1 - 5.2e-05 22.8 0.1 0.00014 21.4 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 ORX85629.1 - 0.0061 16.2 1.5 0.014 15.1 0.0 2.2 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 ORX85629.1 - 0.0085 15.4 0.1 0.024 13.9 0.1 1.7 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_2 PF08442.10 ORX85629.1 - 0.012 15.2 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORX85629.1 - 0.038 13.5 0.1 0.072 12.6 0.1 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF2443 PF10398.9 ORX85630.1 - 0.031 14.3 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) IQ PF00612.27 ORX85630.1 - 0.05 13.4 1.3 0.075 12.9 0.1 1.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif AKNA PF12443.8 ORX85630.1 - 0.053 14.2 0.2 0.053 14.2 0.2 2.4 3 0 0 3 3 3 0 AT-hook-containing transcription factor FAM76 PF16046.5 ORX85630.1 - 0.33 10.3 4.9 0.65 9.3 4.9 1.6 1 1 0 1 1 1 0 FAM76 protein RMF PF04957.12 ORX85631.1 - 0.032 14.4 0.1 0.044 14.0 0.1 1.1 1 0 0 1 1 1 0 Ribosome modulation factor IQ PF00612.27 ORX85632.1 - 2.4e-05 23.7 0.8 9.5e-05 21.9 0.8 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif CCDC92 PF14916.6 ORX85632.1 - 0.0066 16.2 0.2 0.0066 16.2 0.2 3.5 2 1 1 3 3 3 1 Coiled-coil domain of unknown function Lebercilin PF15619.6 ORX85632.1 - 0.032 13.9 5.5 0.12 12.0 1.2 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 ORX85632.1 - 0.039 14.6 3.0 7.1 7.3 2.6 2.8 2 1 0 2 2 2 0 SlyX DUF5320 PF17253.2 ORX85632.1 - 0.17 12.9 1.8 3.7 8.7 0.0 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF1664 PF07889.12 ORX85632.1 - 0.25 11.4 3.6 0.71 9.9 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 ORX85632.1 - 1.3 9.1 6.7 5.2 7.2 0.1 3.1 2 1 1 3 3 3 0 Basic region leucine zipper SH3_1 PF00018.28 ORX85633.1 - 5.9e-11 41.8 0.0 1.6e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORX85633.1 - 8.6e-10 38.2 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORX85633.1 - 1.8e-08 34.1 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mub_B2 PF17966.1 ORX85633.1 - 0.052 14.3 0.1 0.1 13.4 0.1 1.4 1 0 0 1 1 1 0 Mub B2-like domain Acyltransferase PF01553.21 ORX85634.1 - 6.4e-22 77.6 0.0 1.4e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORX85634.1 - 5e-19 68.2 1.4 1.1e-18 67.1 1.4 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_binding_9 PF13454.6 ORX85634.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding IQ PF00612.27 ORX85635.1 - 7.5e-10 37.7 8.6 0.00012 21.6 0.8 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif CCDC92 PF14916.6 ORX85635.1 - 0.0081 15.9 0.2 0.0081 15.9 0.2 3.5 2 1 1 3 3 3 1 Coiled-coil domain of unknown function SlyX PF04102.12 ORX85635.1 - 0.098 13.3 4.8 11 6.8 2.7 2.9 2 1 0 2 2 2 0 SlyX DUF1664 PF07889.12 ORX85635.1 - 0.28 11.2 3.0 0.97 9.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 ORX85635.1 - 0.41 11.7 3.4 4.4 8.4 0.0 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) bZIP_2 PF07716.15 ORX85635.1 - 1.3 9.2 6.5 4.2 7.5 0.1 3.1 2 1 1 3 3 3 0 Basic region leucine zipper RMF PF04957.12 ORX85636.1 - 0.032 14.5 0.1 0.044 14.0 0.1 1.1 1 0 0 1 1 1 0 Ribosome modulation factor IQ PF00612.27 ORX85637.1 - 0.0039 16.9 0.4 0.0039 16.9 0.4 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif CorA PF01544.18 ORX85637.1 - 0.012 15.0 1.3 0.027 13.8 1.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CortBP2 PF09727.9 ORX85637.1 - 0.064 13.2 6.7 0.1 12.5 2.2 2.5 3 0 0 3 3 3 0 Cortactin-binding protein-2 TRAF_BIRC3_bd PF16673.5 ORX85637.1 - 1.6 8.6 6.0 0.82 9.5 0.8 3.0 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain TBCC_N PF16752.5 ORX85637.1 - 1.9 8.9 8.6 0.29 11.6 2.8 2.6 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain ZapB PF06005.12 ORX85638.1 - 0.0031 17.9 0.7 0.0031 17.9 0.7 2.1 2 0 0 2 2 2 1 Cell division protein ZapB bZIP_1 PF00170.21 ORX85638.1 - 0.014 15.5 0.8 0.014 15.5 0.8 3.3 3 1 1 4 4 3 0 bZIP transcription factor YabA PF06156.13 ORX85638.1 - 0.02 15.5 1.5 0.02 15.5 1.5 2.8 1 1 1 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 ORX85638.1 - 0.025 14.8 4.8 0.055 13.7 0.4 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 ORX85638.1 - 0.078 13.0 0.2 0.078 13.0 0.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 ORX85638.1 - 0.14 12.4 3.3 0.58 10.4 1.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.18 ORX85638.1 - 0.18 12.2 3.8 0.17 12.2 1.5 2.2 2 0 0 2 2 1 0 TSC-22/dip/bun family Adeno_E4 PF05385.11 ORX85638.1 - 0.19 11.8 0.4 0.34 11.0 0.4 1.3 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein ADIP PF11559.8 ORX85638.1 - 0.3 11.1 12.1 0.16 12.1 0.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 ORX85638.1 - 0.51 10.1 8.5 0.049 13.4 1.5 2.4 2 0 0 2 2 2 0 Septum formation initiator OmpH PF03938.14 ORX85638.1 - 1.2 9.4 12.2 5.2 7.4 0.0 2.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF4795 PF16043.5 ORX85638.1 - 1.6 8.3 11.7 4.5 6.8 11.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) GIT_CC PF16559.5 ORX85638.1 - 2.5 8.0 6.0 3.8 7.4 2.8 2.7 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor JIP_LZII PF16471.5 ORX85638.1 - 5.5 7.2 9.6 0.96 9.7 2.4 2.9 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II zf-RING_2 PF13639.6 ORX85639.1 - 3.8e-12 46.3 4.7 3.8e-12 46.3 4.7 2.2 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 ORX85639.1 - 2e-10 40.7 4.0 2e-10 40.7 4.0 2.4 3 0 0 3 3 2 1 zinc-ribbon zf-C3HC4_2 PF13923.6 ORX85639.1 - 3.3e-09 36.5 4.4 3.3e-09 36.5 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX85639.1 - 1.9e-07 30.7 3.3 1.9e-07 30.7 3.3 2.2 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORX85639.1 - 1.4e-06 28.1 3.5 1.4e-06 28.1 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX85639.1 - 1.5e-06 28.4 7.4 1.5e-06 28.4 7.4 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORX85639.1 - 3.6e-06 26.9 1.1 3.6e-06 26.9 1.1 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX85639.1 - 7.1e-06 25.9 3.9 7.1e-06 25.9 3.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORX85639.1 - 5.1e-05 23.3 1.2 5.1e-05 23.3 1.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORX85639.1 - 5.5e-05 22.9 10.3 0.00012 21.8 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX85639.1 - 0.00066 19.5 4.3 0.00066 19.5 4.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORX85639.1 - 0.017 14.7 12.1 0.077 12.6 3.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 ORX85639.1 - 0.021 15.0 1.4 0.021 15.0 1.4 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Vps39_2 PF10367.9 ORX85639.1 - 0.11 13.0 0.3 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DZR PF12773.7 ORX85639.1 - 1.7 8.7 8.5 3.5 7.7 1.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.14 ORX85639.1 - 3 7.7 5.5 4.4 7.2 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif HMG_box PF00505.19 ORX85640.1 - 3.5e-22 78.6 3.7 9.2e-22 77.2 3.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX85640.1 - 3.1e-16 59.7 4.1 3.1e-16 59.7 4.1 1.9 2 0 0 2 2 2 1 HMG-box domain RR_TM4-6 PF06459.12 ORX85640.1 - 4.2 7.1 19.8 13 5.5 19.2 1.8 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 ORX85641.1 - 4.4e-11 42.4 0.1 1.4e-10 40.8 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX85641.1 - 6.5e-07 29.0 0.0 7.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 ORX85641.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 ORX85641.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 ORX85642.1 - 3.5e-65 220.0 0.0 4.7e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX85642.1 - 7.9e-49 166.3 0.0 1.1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX85642.1 - 1.6e-20 73.2 4.2 1.6e-11 44.4 0.4 2.7 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 ORX85642.1 - 1.5e-06 27.3 0.4 2.5e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORX85642.1 - 0.00043 19.7 0.0 0.0009 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Abi_2 PF07751.11 ORX85642.1 - 0.0031 17.8 0.1 0.56 10.4 0.0 2.4 1 1 1 2 2 2 2 Abi-like protein Kdo PF06293.14 ORX85642.1 - 0.043 13.2 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX85642.1 - 0.058 12.3 0.6 0.26 10.2 0.6 2.0 1 1 0 1 1 1 0 Haspin like kinase domain DUF1748 PF08520.10 ORX85643.1 - 4.1e-25 87.5 0.0 4.4e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Pyr_redox_2 PF07992.14 ORX85644.1 - 9e-40 136.7 0.1 1.6e-39 135.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 ORX85644.1 - 7.7e-24 83.6 0.0 4e-23 81.3 0.0 2.3 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 ORX85644.1 - 1.1e-20 73.8 7.2 1.8e-16 60.2 3.9 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 ORX85644.1 - 3.3e-18 65.7 0.0 6.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ORX85644.1 - 2.6e-11 43.2 0.0 5.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.27 ORX85644.1 - 6.3e-11 42.7 5.8 4.9e-10 39.8 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 ORX85644.1 - 1.8e-08 34.2 0.1 4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 ORX85644.1 - 7.7e-08 32.1 0.0 3.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain FAD_binding_2 PF00890.24 ORX85644.1 - 0.0021 17.2 1.1 0.072 12.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORX85644.1 - 0.0068 15.7 0.1 0.02 14.2 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ORX85644.1 - 0.032 14.5 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX85644.1 - 0.13 11.3 1.3 0.63 9.1 0.4 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A PTR2 PF00854.21 ORX85645.1 - 3.8e-82 276.2 9.5 5.8e-82 275.6 9.5 1.2 1 0 0 1 1 1 1 POT family DUF3980 PF13140.6 ORX85645.1 - 0.37 11.3 4.0 0.2 12.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) PTR2 PF00854.21 ORX85646.1 - 2.8e-82 276.7 9.2 4.4e-82 276.0 9.2 1.2 1 0 0 1 1 1 1 POT family DUF3980 PF13140.6 ORX85646.1 - 0.79 10.2 4.7 0.21 12.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) FtsJ PF01728.19 ORX85689.1 - 5.1e-69 231.9 0.0 6.2e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase TBPIP PF07106.13 ORX85690.1 - 1.4e-24 85.8 0.3 3.8e-24 84.4 0.1 1.9 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 ORX85690.1 - 1.2e-10 41.3 1.1 1.2e-10 41.3 1.1 3.3 3 1 0 3 3 3 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 ORX85690.1 - 2.1e-06 28.0 0.7 5.5e-06 26.7 0.4 2.0 2 1 0 2 2 2 1 Penicillinase repressor PilJ PF13675.6 ORX85690.1 - 0.0012 18.9 2.7 0.0019 18.2 0.2 2.1 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_1 PF00170.21 ORX85690.1 - 0.02 15.0 4.8 1.8 8.8 0.5 2.8 1 1 1 2 2 2 0 bZIP transcription factor DUF4391 PF14335.6 ORX85690.1 - 0.023 14.4 2.3 0.029 14.1 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4391) TSC22 PF01166.18 ORX85690.1 - 0.14 12.5 4.8 0.18 12.2 0.7 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 ORX85690.1 - 0.17 9.8 2.2 0.2 9.5 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 ORX85690.1 - 0.28 10.5 3.8 0.41 10.0 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 ORX85690.1 - 0.32 10.8 9.6 0.23 11.3 3.9 2.7 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 ORX85690.1 - 0.72 10.5 7.9 8.1 7.1 7.8 2.4 1 1 0 1 1 1 0 Initiation control protein YabA MSC PF09402.10 ORX85690.1 - 2.4 7.5 8.5 4.7 6.6 8.5 1.5 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain EF-hand_13 PF17958.1 ORX85691.1 - 4.5e-24 84.1 0.0 1.1e-22 79.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ORX85691.1 - 5.4e-15 55.6 1.7 6.6e-14 52.1 0.5 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 ORX85691.1 - 0.00036 19.9 2.3 0.068 12.7 0.1 4.1 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 ORX85691.1 - 0.00037 20.2 1.0 0.049 13.6 0.1 4.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 ORX85691.1 - 0.00061 19.2 0.2 0.0079 15.7 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORX85691.1 - 0.01 15.6 0.5 0.52 10.2 0.0 3.9 6 0 0 6 6 6 0 EF-hand domain pair zf-HC5HC2H_2 PF13832.6 ORX85692.1 - 5.3e-22 78.1 11.7 3e-21 75.6 2.5 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORX85692.1 - 4.5e-14 52.5 1.7 4.5e-14 52.5 1.7 3.4 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 ORX85692.1 - 3.2e-10 39.4 4.7 3.2e-10 39.4 4.7 2.7 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 ORX85692.1 - 1.5e-07 31.2 24.6 4.5e-06 26.5 11.1 3.3 3 0 0 3 3 3 2 PHD-finger SHE3 PF17078.5 ORX85692.1 - 0.024 14.3 2.4 0.039 13.7 2.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TMF_DNA_bd PF12329.8 ORX85692.1 - 0.024 14.6 2.7 0.057 13.4 2.7 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding C1_2 PF03107.16 ORX85692.1 - 0.027 14.8 0.9 0.027 14.8 0.9 3.7 3 0 0 3 3 3 0 C1 domain JIP_LZII PF16471.5 ORX85692.1 - 0.055 13.7 0.8 0.14 12.4 0.8 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HCV_NS5a_1b PF08301.13 ORX85692.1 - 0.079 13.5 0.1 0.21 12.2 0.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b DUF3450 PF11932.8 ORX85692.1 - 0.55 9.5 4.3 0.88 8.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cript PF10235.9 ORX85693.1 - 1.9e-31 108.5 11.0 1.9e-31 108.5 11.0 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zinc_ribbon_2 PF13240.6 ORX85693.1 - 0.0081 15.8 10.8 0.52 10.1 4.3 3.4 3 0 0 3 3 3 1 zinc-ribbon domain DUF2616 PF11077.8 ORX85693.1 - 0.043 13.5 6.6 0.05 13.3 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DUF2039 PF10217.9 ORX85693.1 - 0.26 11.6 21.4 4.4 7.7 21.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 ORX85693.1 - 0.41 11.0 11.4 0.73 10.3 4.4 2.3 2 0 0 2 2 2 0 Rhodanase C-terminal zf-C3HC4_3 PF13920.6 ORX85693.1 - 0.55 10.1 17.5 4.9 7.1 9.3 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 ORX85693.1 - 0.94 9.6 12.8 2.3 8.4 6.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-H2C2_2 PF13465.6 ORX85695.1 - 9.9e-14 51.0 6.8 9.9e-08 32.1 0.7 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX85695.1 - 1.4e-12 47.3 22.4 2.4e-05 24.5 4.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX85695.1 - 1.5e-11 44.1 18.8 0.00019 22.0 2.9 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX85695.1 - 5.8e-09 35.7 9.6 0.00084 19.3 0.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HE PF16278.5 ORX85695.1 - 0.00019 21.8 10.2 0.044 14.2 0.3 2.6 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORX85695.1 - 0.00041 20.5 7.9 0.91 9.9 1.7 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX85695.1 - 0.00087 19.5 7.1 0.0079 16.5 3.8 2.0 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 ORX85695.1 - 0.0012 19.2 11.7 0.27 11.7 1.0 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type C1_1 PF00130.22 ORX85695.1 - 0.0035 17.2 0.7 0.0035 17.2 0.7 1.7 2 1 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 ORX85695.1 - 0.0039 17.3 5.6 0.39 10.9 0.0 2.8 2 1 1 3 3 3 2 Zinc ribbon domain zf_ZIC PF18366.1 ORX85695.1 - 0.0061 16.7 5.8 1.7 8.8 0.2 3.1 2 1 1 3 3 3 1 Zic proteins zinc finger domain DUF2757 PF10955.8 ORX85695.1 - 0.0062 16.8 2.8 0.83 10.0 0.3 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2757) zf-C2H2_11 PF16622.5 ORX85695.1 - 0.016 14.9 13.2 0.95 9.3 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type HypA PF01155.19 ORX85695.1 - 0.025 14.6 1.3 0.029 14.4 1.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Scramblase PF03803.15 ORX85695.1 - 0.041 13.2 0.1 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 Scramblase zf-AN1 PF01428.16 ORX85695.1 - 0.057 13.6 15.5 1.5 9.0 8.6 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger HalOD2 PF18547.1 ORX85695.1 - 0.064 13.2 0.6 0.19 11.6 0.6 1.8 1 1 0 1 1 1 0 Halobacterial output domain 2 C1_4 PF07975.12 ORX85695.1 - 0.07 13.4 11.8 0.17 12.1 6.6 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 ORX85695.1 - 0.074 13.0 0.3 0.074 13.0 0.3 3.7 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 ORX85695.1 - 0.079 12.9 9.3 2.8 7.9 0.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORX85695.1 - 0.092 12.7 4.6 0.16 12.0 2.2 2.2 1 1 1 2 2 2 0 zinc-ribbons zf_UBZ PF18439.1 ORX85695.1 - 0.28 10.8 7.2 1.7 8.3 0.5 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-CHY PF05495.12 ORX85695.1 - 0.32 11.5 11.3 0.087 13.3 4.5 2.4 1 1 1 2 2 2 0 CHY zinc finger ADK_lid PF05191.14 ORX85695.1 - 0.5 10.4 6.4 4.5 7.3 3.3 2.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid Rep_fac-A_C PF08646.10 ORX85695.1 - 1.2 8.9 5.9 41 3.9 5.9 2.1 1 1 0 1 1 1 0 Replication factor-A C terminal domain IBR PF01485.21 ORX85695.1 - 2 8.7 10.3 0.35 11.1 4.2 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 ORX85695.1 - 7 6.7 9.6 9.5 6.3 4.1 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3421 PF11901.8 ORX85748.1 - 3.7e-19 68.8 1.7 5.1e-10 39.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Cyclin_N PF00134.23 ORX85749.1 - 3.3e-08 33.3 0.0 4.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX85749.1 - 1.3e-05 25.7 0.0 1.4e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin S4 PF01479.25 ORX85750.1 - 3.3e-08 33.1 0.1 7.4e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 S4 domain Ribosomal_S4e PF00900.20 ORX85750.1 - 5.6e-05 23.0 0.1 0.00014 21.7 0.1 1.9 1 1 0 1 1 1 1 Ribosomal family S4e HAD_SAK_1 PF10307.9 ORX85751.1 - 1.3e-52 178.5 0.5 1.8e-52 178.1 0.5 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins tRNA_lig_CPD PF08302.11 ORX85751.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Ribosomal_S11 PF00411.19 ORX85752.1 - 1.2e-47 160.8 1.3 1.5e-47 160.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S28e PF01200.18 ORX85753.1 - 1.4e-33 114.7 1.2 1.6e-33 114.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORX85753.1 - 0.042 14.2 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORX85753.1 - 0.058 13.4 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region WD40 PF00400.32 ORX85754.1 - 7.1e-07 29.8 2.3 0.0065 17.3 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORX85754.1 - 8.3e-06 25.0 2.1 0.021 13.8 0.4 2.6 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 ORX85754.1 - 2.2e-05 24.7 0.0 0.11 12.8 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORX85754.1 - 0.016 15.2 0.0 0.057 13.4 0.0 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat ISP1_C PF18161.1 ORX85754.1 - 0.17 11.9 0.4 0.61 10.1 0.1 2.0 2 1 0 2 2 2 0 ISP1 C-terminal Cyclin_N PF00134.23 ORX85756.1 - 2.4e-12 46.7 0.2 2.9e-12 46.4 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX85756.1 - 5.3e-11 43.1 0.1 6.7e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin NOD PF06816.13 ORX85756.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NOTCH protein BTB PF00651.31 ORX85757.1 - 0.0028 17.9 0.6 0.019 15.2 0.6 2.1 1 1 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 ORX85758.1 - 2e-08 34.3 13.8 4.7e-07 30.0 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX85758.1 - 1.3e-06 28.5 24.9 3.3e-05 24.1 2.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX85758.1 - 7.4e-05 23.3 20.3 0.004 17.9 1.6 3.3 3 0 0 3 3 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORX85758.1 - 0.0024 18.1 4.9 0.0091 16.3 4.9 2.0 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORX85758.1 - 0.011 16.0 7.9 0.86 10.0 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORX85758.1 - 0.019 15.3 4.8 1.3 9.4 0.1 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORX85758.1 - 0.02 15.3 0.5 0.02 15.3 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORX85758.1 - 0.03 14.2 6.8 3.1 7.8 2.7 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type UBZ_FAAP20 PF15750.5 ORX85758.1 - 0.44 10.5 5.4 13 5.9 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-MYST PF17772.1 ORX85758.1 - 2.9 7.5 5.7 3.8 7.2 0.7 2.6 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 ORX85758.1 - 9.8 6.3 11.7 0.77 9.8 1.9 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Aldo_ket_red PF00248.21 ORX85759.1 - 1.1e-71 241.5 0.1 1.2e-71 241.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BPL_C PF02237.17 ORX85759.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Lig_chan PF00060.26 ORX85814.1 - 0.17 11.7 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4805 PF16063.5 ORX85818.1 - 0.034 13.5 1.5 0.041 13.2 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Pox_RNA_Pol_19 PF05320.12 ORX85819.1 - 1.4 8.9 4.0 1.4 8.8 3.4 1.4 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Aa_trans PF01490.18 ORX85881.1 - 5.6e-81 272.3 38.3 6.4e-81 272.1 38.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX85881.1 - 5.8e-05 22.3 13.7 5.8e-05 22.3 13.7 2.9 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3278 PF11683.8 ORX85881.1 - 0.023 14.8 1.2 0.023 14.8 1.2 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3278) Presenilin PF01080.17 ORX85883.1 - 5.4e-119 397.5 0.7 7.9e-119 397.0 0.7 1.2 1 0 0 1 1 1 1 Presenilin zf-MYND PF01753.18 ORX85883.1 - 3.5e-09 36.6 11.7 5.2e-09 36.0 11.7 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORX85883.1 - 0.022 14.9 5.3 0.041 14.0 5.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 ORX85883.1 - 0.12 12.2 8.8 0.23 11.4 8.8 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 ORX85883.1 - 7.5 6.9 10.1 14 6.0 10.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TFIIS_C PF01096.18 ORX85884.1 - 6.7e-19 67.5 6.3 6.7e-19 67.5 6.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORX85884.1 - 1.2e-09 37.9 1.3 1.2e-09 37.9 1.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 ORX85884.1 - 0.00075 19.4 9.1 0.018 15.0 3.1 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORX85884.1 - 0.023 14.7 0.3 0.023 14.7 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbons PH_10 PF15411.6 ORX85884.1 - 0.06 13.6 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain zf-TFIIB PF13453.6 ORX85884.1 - 0.065 12.6 3.9 0.93 8.9 1.0 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Auto_anti-p27 PF06677.12 ORX85884.1 - 0.75 10.0 5.2 3.4 7.9 0.6 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Baculo_LEF5_C PF11792.8 ORX85884.1 - 3.6 7.4 7.9 0.73 9.6 2.6 2.4 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Ribosomal_L1 PF00687.21 ORX85885.1 - 1.9e-47 161.7 1.5 2.3e-47 161.4 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mod_r PF07200.13 ORX85885.1 - 0.034 14.2 1.4 0.091 12.9 0.2 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Aminotran_1_2 PF00155.21 ORX85886.1 - 1.4e-39 136.3 0.0 1.9e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX85886.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Lipase_3 PF01764.25 ORX85942.1 - 5.1e-34 117.2 0.0 8.7e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX85942.1 - 3e-05 23.7 0.1 0.00018 21.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX85942.1 - 0.0023 18.6 0.0 0.0028 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORX85942.1 - 0.003 17.3 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX85942.1 - 0.0088 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 ORX85942.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 ORX85942.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hpt PF01627.23 ORX85942.1 - 0.19 12.0 0.2 50 4.2 0.0 3.2 3 0 0 3 3 3 0 Hpt domain Ecl1 PF12855.7 ORX85943.1 - 6 8.0 35.6 8.6 7.5 35.6 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins SOG2 PF10428.9 ORX85943.1 - 8.5 5.4 20.9 11 5.1 20.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein eIF-1a PF01176.19 ORX85944.1 - 7e-24 83.4 0.1 9.5e-24 83.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_S30 PF04758.14 ORX85945.1 - 3.5e-29 100.8 9.6 3.7e-29 100.7 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 adh_short PF00106.25 ORX85946.1 - 1.2e-41 142.3 0.0 1.5e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX85946.1 - 6e-26 91.4 0.0 7.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 ORX85946.1 - 2.3e-06 26.9 0.1 3.1e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORX85946.1 - 7.7e-06 25.9 0.1 2e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 ORX85946.1 - 0.00094 19.3 0.1 0.0019 18.3 0.1 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORX85946.1 - 0.0016 19.1 0.0 0.003 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 ORX85946.1 - 0.0061 16.1 0.2 0.053 13.0 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 ORX85946.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 ORX85946.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Aminotran_1_2 PF00155.21 ORX85947.1 - 5.5e-76 256.1 0.0 6.7e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX85947.1 - 4e-05 22.3 0.0 6.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORX85947.1 - 0.00061 18.8 0.0 0.00097 18.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Allantoicase PF03561.15 ORX85948.1 - 4.2e-89 295.9 0.0 3.3e-46 156.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat MDM31_MDM32 PF08118.11 ORX85949.1 - 1.6e-176 588.0 2.2 2e-176 587.8 2.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HSF_DNA-bind PF00447.17 ORX85950.1 - 9.1e-30 103.1 2.7 1.1e-29 102.8 2.7 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding CelTOS PF18659.1 ORX85951.1 - 0.078 13.4 0.1 2.2 8.7 0.0 2.5 1 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Fib_alpha PF08702.10 ORX85952.1 - 0.0011 19.2 10.9 0.0011 19.2 10.9 4.5 2 1 2 4 4 4 2 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 ORX85952.1 - 3.9 6.9 81.7 3.4 7.1 15.0 4.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 ORX85952.1 - 9.2 5.7 74.3 2.1 7.8 18.6 4.5 1 1 3 4 4 4 0 Intermediate filament protein Pro_CA PF00484.19 ORX85954.1 - 3.1e-51 173.8 0.3 4.2e-51 173.3 0.3 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 ORX85955.1 - 1.6e-51 174.7 1.4 1.9e-51 174.5 1.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PHD_2 PF13831.6 ORX85955.1 - 0.45 10.1 0.0 0.45 10.1 0.0 3.8 4 1 0 4 4 4 0 PHD-finger Abhydrolase_1 PF00561.20 ORX85956.1 - 1.3e-23 83.9 0.2 1.6e-23 83.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 ORX85956.1 - 3.7e-22 77.7 0.0 6.5e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 ORX85956.1 - 1.9e-06 27.4 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX85956.1 - 0.00036 21.2 0.0 0.00045 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 ORX85956.1 - 0.011 15.5 0.1 0.65 9.6 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) AXE1 PF05448.12 ORX85956.1 - 0.085 11.5 0.2 0.77 8.4 0.2 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) NmrA PF05368.13 ORX86011.1 - 9e-19 67.9 0.0 1.1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX86011.1 - 2.1e-13 50.6 0.0 3.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORX86011.1 - 0.015 14.5 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein Peptidase_M28 PF04389.17 ORX86012.1 - 1.3e-37 129.4 0.0 2.1e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ORX86012.1 - 0.0008 18.5 0.0 0.014 14.4 0.0 2.1 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORX86012.1 - 0.0028 17.4 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CitMHS PF03600.16 ORX86013.1 - 1.8 7.7 6.8 3.7 6.7 6.8 1.5 1 1 0 1 1 1 0 Citrate transporter Nup35_RRM PF05172.13 ORX86015.1 - 1.4e-20 73.1 0.0 3.5e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORX86015.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Occludin_ELL PF07303.13 ORX86016.1 - 5.8e-08 33.4 2.3 1.8e-07 31.8 2.3 1.8 1 0 0 1 1 1 1 Occludin homology domain ELL PF10390.9 ORX86016.1 - 3.2e-07 30.1 0.1 3.2e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL CLP1_N PF16573.5 ORX86016.1 - 0.069 13.4 0.3 0.24 11.6 0.2 1.9 1 1 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor UPF0449 PF15136.6 ORX86016.1 - 2.3 8.7 7.5 6.5 7.3 0.2 3.1 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Gtr1_RagA PF04670.12 ORX86017.1 - 4.4e-104 346.9 1.8 5.4e-104 346.6 1.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX86017.1 - 7.8e-08 32.6 0.0 2.1e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX86017.1 - 9.3e-08 31.8 0.1 1.8e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 ORX86017.1 - 4.1e-07 29.6 0.0 6.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX86017.1 - 9.7e-06 25.3 0.1 1.2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX86017.1 - 9.9e-06 25.6 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX86017.1 - 0.019 14.9 0.3 0.66 9.9 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase ABC_sub_bind PF04392.12 ORX86017.1 - 0.17 11.1 0.2 1 8.6 0.1 1.9 2 0 0 2 2 2 0 ABC transporter substrate binding protein I_LWEQ PF01608.17 ORX86018.1 - 2.2e-49 167.6 12.7 2.2e-49 167.6 12.7 7.0 3 2 2 6 6 6 2 I/LWEQ domain ANTH PF07651.16 ORX86018.1 - 5.4e-12 45.3 0.0 5.4e-12 45.3 0.0 3.8 3 1 0 3 3 3 1 ANTH domain Spc7 PF08317.11 ORX86018.1 - 0.0029 16.6 14.2 0.0029 16.6 14.2 5.4 3 1 3 6 6 6 2 Spc7 kinetochore protein DUF4041 PF13250.6 ORX86018.1 - 1.7 8.6 4.6 4.5 7.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Frizzled PF01534.17 ORX86019.1 - 0.00018 20.7 9.8 0.00018 20.7 9.8 1.7 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region GPR_Gpa2_C PF11970.8 ORX86019.1 - 0.0061 16.6 0.6 0.027 14.5 0.6 2.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term PgaD PF13994.6 ORX86019.1 - 0.035 14.2 1.5 0.035 14.2 1.5 2.0 2 1 1 3 3 3 0 PgaD-like protein MRAP PF15183.6 ORX86019.1 - 0.064 13.2 0.8 0.19 11.7 0.8 1.8 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family MFS_1 PF07690.16 ORX86020.1 - 1.7e-43 148.9 18.5 1.5e-42 145.8 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX86020.1 - 1.1e-07 31.1 1.9 1.1e-07 31.1 1.9 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 ORX86020.1 - 2e-06 26.7 13.9 4.8e-06 25.4 11.3 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 ORX86020.1 - 5.5e-05 21.8 0.4 9.9e-05 20.9 0.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ORX86020.1 - 0.0021 17.0 2.5 0.0021 17.0 2.5 2.4 1 1 1 2 2 2 1 Sugar-tranasporters, 12 TM DUF1772 PF08592.11 ORX86020.1 - 1.4 9.2 9.1 0.65 10.3 1.2 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) C2 PF00168.30 ORX86021.1 - 1.6e-13 50.8 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain MTS PF05175.14 ORX86022.1 - 2.8e-09 36.7 0.0 4.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORX86022.1 - 1.5e-07 31.3 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX86022.1 - 6.7e-06 26.7 0.0 1.2e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX86022.1 - 2.2e-05 24.2 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 ORX86022.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 ORX86022.1 - 0.0006 19.6 0.0 0.0022 17.7 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF938 PF06080.12 ORX86022.1 - 0.00063 19.6 0.0 0.00091 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 ORX86022.1 - 0.0031 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 ORX86022.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa PCMT PF01135.19 ORX86022.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 ORX86022.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ORX86022.1 - 0.027 14.5 0.0 0.042 13.8 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORX86022.1 - 0.029 15.0 0.0 0.051 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORX86022.1 - 0.046 13.4 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_15 PF09445.10 ORX86022.1 - 0.048 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 ORX86022.1 - 0.063 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmC_N PF17827.1 ORX86022.1 - 0.084 13.5 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 PrmC N-terminal domain Ubie_methyltran PF01209.18 ORX86022.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GDP_Man_Dehyd PF16363.5 ORX86022.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX86022.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Carn_acyltransf PF00755.20 ORX86023.1 - 9.9e-184 612.2 0.0 1.2e-183 612.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YhdX PF17444.2 ORX86023.1 - 0.12 12.2 0.3 1 9.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized YhdX-like WD40 PF00400.32 ORX86024.1 - 1.6e-55 183.8 28.3 1.5e-08 35.2 0.7 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX86024.1 - 9.3e-18 64.3 8.3 0.00043 20.5 0.4 6.9 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX86024.1 - 8.2e-14 51.9 1.1 4.9e-07 29.8 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORX86024.1 - 4.2e-05 21.8 1.2 0.00016 19.8 0.2 2.2 2 0 0 2 2 2 1 IKI3 family BBS2_Mid PF14783.6 ORX86024.1 - 0.0055 16.7 0.3 4.8 7.3 0.0 3.6 5 1 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.14 ORX86024.1 - 0.084 11.9 4.9 0.33 10.0 0.9 3.1 3 1 1 4 4 4 0 Coatomer WD associated region bZIP_1 PF00170.21 ORX86025.1 - 2.4e-11 43.6 7.1 4.2e-11 42.8 7.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.8 ORX86025.1 - 1.9e-07 31.3 2.8 1.6e-06 28.3 2.7 2.6 1 1 0 1 1 1 1 Aft1 HRA domain Aft1_OSA PF11785.8 ORX86025.1 - 1.1e-06 28.9 3.0 3.5e-06 27.4 2.3 2.3 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 ORX86025.1 - 4e-06 26.8 7.5 7.8e-06 25.9 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX86025.1 - 0.00022 21.7 5.3 0.00053 20.5 5.3 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 ORX86025.1 - 0.0043 17.3 0.3 0.0074 16.5 0.3 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Macoilin PF09726.9 ORX86025.1 - 1.5 7.3 13.1 1.9 6.9 13.1 1.1 1 0 0 1 1 1 0 Macoilin family ASD2 PF08687.11 ORX86025.1 - 3.1 7.3 12.5 2.6 7.5 11.3 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 RRM_1 PF00076.22 ORX86026.1 - 1.9e-33 114.1 2.3 5.3e-19 67.8 0.5 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX86026.1 - 9.4e-06 25.2 0.0 0.062 12.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ORX86026.1 - 0.00024 21.4 0.2 0.38 11.0 0.0 3.3 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 ORX86026.1 - 0.0063 16.6 0.3 0.32 11.2 0.1 3.0 2 2 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 ORX86026.1 - 0.078 13.1 0.7 1.4 9.1 0.0 2.7 2 1 0 2 2 2 0 Limkain b1 OB_RNB PF08206.11 ORX86026.1 - 0.15 11.8 0.5 15 5.4 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Arm-DNA-bind_4 PF14657.6 ORX86026.1 - 0.34 10.7 1.9 0.69 9.7 1.9 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain EamA PF00892.20 ORX86027.1 - 4.4e-28 98.1 34.4 9.1e-16 58.3 13.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF4407 PF14362.6 ORX86027.1 - 0.66 9.3 1.5 0.71 9.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) REV1_C PF16727.5 ORX86028.1 - 0.11 12.9 0.5 0.44 11.0 0.5 2.1 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain ABC1 PF03109.16 ORX86029.1 - 1.8e-32 112.0 0.1 3.4e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORX86029.1 - 1.2e-05 25.0 0.3 4.4e-05 23.1 0.0 2.0 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.25 ORX86029.1 - 0.00091 18.7 0.0 0.043 13.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 ORX86029.1 - 0.067 13.1 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-bind_4 PF13837.6 ORX86030.1 - 1.1e-13 51.3 1.7 9.3e-06 25.9 0.2 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX86030.1 - 0.00097 19.4 1.1 0.38 11.1 0.1 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 ORX86030.1 - 0.0024 18.0 0.0 3.1 8.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORX86030.1 - 0.95 10.5 3.3 15 6.7 0.5 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain TRAM_LAG1_CLN8 PF03798.16 ORX86031.1 - 8e-15 55.1 10.3 1.1e-14 54.7 10.3 1.2 1 0 0 1 1 1 1 TLC domain GPI-anchored PF10342.9 ORX86032.1 - 1.2e-10 42.0 0.1 1.2e-10 42.0 0.1 3.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LAP1C PF05609.12 ORX86032.1 - 2.2 7.3 31.9 3 6.9 31.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 ORX86032.1 - 3.4 4.7 32.5 4.1 4.4 32.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BUD22 PF09073.10 ORX86032.1 - 5.8 6.1 43.7 10 5.4 43.7 1.3 1 0 0 1 1 1 0 BUD22 Allantoicase PF03561.15 ORX86086.1 - 1.1e-71 239.4 0.0 2.3e-35 121.7 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat ABC_tran PF00005.27 ORX86087.1 - 1.7e-50 171.1 0.0 4.9e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 ORX86087.1 - 1.9e-47 161.4 54.7 6.7e-31 107.3 20.3 3.3 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 ORX86087.1 - 1.6e-13 51.1 3.4 0.0031 17.4 0.2 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORX86087.1 - 8.9e-09 36.0 0.4 0.00033 21.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORX86087.1 - 2e-07 31.7 1.8 0.014 15.9 0.2 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX86087.1 - 2.9e-06 27.3 2.7 0.0028 17.6 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 ORX86087.1 - 7.3e-06 25.6 1.0 3.6 7.0 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 ORX86087.1 - 3.3e-05 23.9 0.1 0.021 14.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 ORX86087.1 - 3.5e-05 23.5 0.4 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX86087.1 - 4.9e-05 23.6 2.0 0.021 15.1 0.5 3.8 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX86087.1 - 0.00031 21.3 0.1 0.046 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORX86087.1 - 0.00058 19.5 0.1 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ORX86087.1 - 0.0009 19.5 0.4 0.5 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORX86087.1 - 0.00093 19.2 0.1 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 ORX86087.1 - 0.0013 18.9 0.2 0.54 10.5 0.1 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 ORX86087.1 - 0.0021 17.8 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORX86087.1 - 0.0027 18.1 0.0 0.042 14.3 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX86087.1 - 0.0033 17.4 0.0 0.87 9.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 ORX86087.1 - 0.0043 17.1 0.9 1.6 8.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 ORX86087.1 - 0.0079 15.9 0.2 0.52 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORX86087.1 - 0.0079 16.4 0.0 4.4 7.6 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 ORX86087.1 - 0.01 15.0 0.1 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit MobB PF03205.14 ORX86087.1 - 0.024 14.6 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 ORX86087.1 - 0.03 14.5 0.3 0.72 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORX86087.1 - 0.037 13.7 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ORX86087.1 - 0.053 12.7 0.1 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 ORX86087.1 - 0.063 13.0 0.1 6.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 ORX86087.1 - 0.07 11.8 0.7 1.2 7.6 0.6 2.4 3 0 0 3 3 3 0 AAA domain CobA_CobO_BtuR PF02572.15 ORX86087.1 - 0.082 13.2 0.0 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_14 PF13173.6 ORX86087.1 - 0.084 12.9 0.2 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX86087.1 - 0.089 13.1 0.1 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORX86087.1 - 0.09 12.5 0.2 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 ORX86087.1 - 0.11 12.1 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 ORX86087.1 - 0.13 12.7 0.3 0.76 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ORX86087.1 - 0.14 11.4 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain dNK PF01712.19 ORX86087.1 - 0.16 11.8 0.1 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 ORX86087.1 - 0.16 12.4 0.2 4.4 7.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 ORX86087.1 - 0.18 11.4 1.0 2.8 7.5 0.0 2.9 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 ORX86087.1 - 0.2 11.8 0.5 9.2 6.3 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Pox_A32 PF04665.12 ORX86087.1 - 0.24 10.8 0.7 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 ORX86087.1 - 0.28 10.7 0.7 1.1 8.7 0.2 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 ORX86087.1 - 0.33 10.8 1.1 1.2 9.0 0.1 2.3 3 0 0 3 3 2 0 NTPase FtsK_SpoIIIE PF01580.18 ORX86087.1 - 0.46 9.8 1.3 19 4.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 ORX86087.1 - 0.73 9.5 1.8 2.1 7.9 0.4 2.1 2 0 0 2 2 2 0 AAA ATPase domain GPI-anchored PF10342.9 ORX86088.1 - 2.2e-13 50.8 0.1 2.2e-13 50.8 0.1 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_61 PF03443.14 ORX86088.1 - 0.0089 16.0 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 ORX86088.1 - 0.058 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory DUF4442 PF14539.6 ORX86090.1 - 1.8e-26 92.9 0.0 2.1e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Fasciclin PF02469.22 ORX86091.1 - 7.9e-46 155.4 0.0 7.5e-23 81.2 0.0 3.4 3 0 0 3 3 3 3 Fasciclin domain Skp1_POZ PF03931.15 ORX86091.1 - 1.2e-06 28.5 1.6 3.1e-06 27.2 0.0 2.5 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain ICE2 PF08426.10 ORX86092.1 - 1.9e-22 80.0 26.9 6.9e-19 68.2 26.8 3.1 1 1 0 1 1 1 1 ICE2 Peptidase_M16_C PF05193.21 ORX86149.1 - 4.3e-09 36.7 0.1 6.5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain LcrV PF04792.12 ORX86149.1 - 0.0039 16.5 0.1 0.22 10.7 0.0 2.0 1 1 1 2 2 2 2 V antigen (LcrV) protein YdjM PF04307.14 ORX86150.1 - 0.16 11.3 2.9 0.22 10.8 2.9 1.4 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Histone PF00125.24 ORX86151.1 - 7.9e-21 74.8 0.4 9.8e-21 74.5 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORX86151.1 - 5e-07 29.9 0.2 9.5e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORX86151.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 ORX86151.1 - 0.0059 16.7 0.4 0.007 16.4 0.4 1.2 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 ORX86151.1 - 0.0076 16.5 0.0 0.0091 16.2 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein Neurochondrin PF05536.11 ORX86152.1 - 1.2e-37 129.6 12.8 2.2e-37 128.7 12.8 1.4 1 1 0 1 1 1 1 Neurochondrin EST1_DNA_bind PF10373.9 ORX86152.1 - 0.017 14.6 1.2 0.017 14.6 1.2 2.6 2 1 1 3 3 3 0 Est1 DNA/RNA binding domain MutS_V PF00488.21 ORX86153.1 - 4e-83 278.1 0.1 6.8e-83 277.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORX86153.1 - 4e-37 128.3 1.5 4e-37 128.3 1.5 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ORX86153.1 - 2.3e-18 66.8 0.7 7e-18 65.2 0.1 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORX86153.1 - 1.3e-15 57.5 0.3 6.7e-15 55.2 0.3 2.4 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 ORX86153.1 - 3.2e-12 46.7 0.0 7.5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain I Peptidase_M16 PF00675.20 ORX86153.1 - 0.2 11.6 0.5 0.64 10.0 0.1 2.1 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Ribosomal_L18 PF17135.4 ORX86154.1 - 3.3e-97 323.3 3.4 3.7e-97 323.2 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORX86154.1 - 0.0058 17.3 0.1 0.018 15.7 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DHO_dh PF01180.21 ORX86155.1 - 2.5e-66 223.9 0.0 2.9e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 ORX86155.1 - 3.2e-05 23.1 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 ORX86155.1 - 0.0069 15.9 0.0 0.063 12.7 0.0 2.2 2 0 0 2 2 2 1 PcrB family IMPDH PF00478.25 ORX86155.1 - 0.063 12.3 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Peptidase_M48 PF01435.18 ORX86156.1 - 1e-19 71.1 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 ORX86156.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 ORX86156.1 - 0.044 13.7 0.3 0.19 11.7 0.3 2.0 1 1 0 1 1 1 0 IrrE N-terminal-like domain DUF4157 PF13699.6 ORX86156.1 - 0.15 12.3 0.1 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Orn_Arg_deC_N PF02784.16 ORX86157.1 - 6.1e-81 271.4 0.0 8.3e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORX86157.1 - 3.9e-20 71.9 0.0 4.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IucA_IucC PF04183.12 ORX86158.1 - 7.6e-28 97.7 0.0 1.2e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 ORX86158.1 - 2.2e-13 50.9 0.0 5.6e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter PhoLip_ATPase_C PF16212.5 ORX86159.1 - 5e-87 291.8 26.8 5e-87 291.8 26.8 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX86159.1 - 3e-25 87.7 8.0 8.8e-25 86.2 8.0 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORX86159.1 - 2.7e-11 43.4 0.0 9.5e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX86159.1 - 8.5e-11 42.5 0.4 8e-06 26.3 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX86159.1 - 4.7e-08 32.7 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORX86159.1 - 0.0042 16.9 0.6 0.019 14.7 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ric8 PF10165.9 ORX86160.1 - 3.9e-104 349.3 0.0 4.7e-104 349.0 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn APG17 PF04108.12 ORX86161.1 - 6.5e-46 157.2 14.9 7.5e-46 157.0 14.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 TelA PF05816.11 ORX86161.1 - 0.0011 18.2 1.7 0.0016 17.6 1.7 1.5 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF4201 PF13870.6 ORX86161.1 - 0.0056 16.4 3.2 0.0056 16.4 3.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) DHR10 PF18595.1 ORX86161.1 - 0.061 13.4 0.5 0.061 13.4 0.5 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 ORX86161.1 - 0.093 13.3 10.8 27 5.4 10.8 3.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal SOAR PF16533.5 ORX86161.1 - 0.099 12.6 2.1 0.33 11.0 0.5 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region TMPIT PF07851.13 ORX86161.1 - 0.1 11.8 5.2 0.79 8.9 0.5 2.3 1 1 1 2 2 2 0 TMPIT-like protein EzrA PF06160.12 ORX86161.1 - 0.13 10.4 15.2 0.0096 14.1 5.5 2.5 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 ORX86161.1 - 0.28 11.2 5.0 4.3 7.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORX86161.1 - 0.3 11.5 4.1 12 6.4 0.1 3.3 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-R PF06729.12 ORX86161.1 - 0.33 10.9 3.2 0.37 10.7 0.5 2.2 1 1 1 2 2 2 0 Kinetochore component, CENP-R HMMR_N PF15905.5 ORX86161.1 - 0.62 9.5 12.2 0.14 11.7 7.4 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SpecificRecomb PF10136.9 ORX86161.1 - 0.71 8.1 4.0 0.89 7.8 4.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase COG2 PF06148.11 ORX86161.1 - 0.75 9.9 7.0 0.17 12.0 2.4 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.18 ORX86161.1 - 1.7 7.9 9.2 0.37 10.1 4.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Plk4_PB2 PF18409.1 ORX86161.1 - 4.6 8.0 6.3 15 6.3 0.8 3.1 1 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Lectin_leg-like PF03388.13 ORX86162.1 - 6.1e-67 225.3 0.6 8.3e-67 224.9 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family Lectin_legB PF00139.19 ORX86162.1 - 8.9e-07 28.7 0.9 4.8e-05 23.0 0.9 2.1 1 1 0 1 1 1 1 Legume lectin domain Myco_arth_vir_N PF09610.10 ORX86162.1 - 0.26 11.4 1.0 0.59 10.3 1.0 1.6 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) CBM_21 PF03370.13 ORX86163.1 - 1.1e-30 106.1 1.2 2e-30 105.3 1.2 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORX86163.1 - 1.9e-09 38.0 0.3 5.8e-09 36.4 0.3 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Y_phosphatase PF00102.27 ORX86164.1 - 4.2e-79 265.4 0.2 5.1e-79 265.2 0.2 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORX86164.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 ORX86164.1 - 0.065 13.1 2.7 0.11 12.4 1.9 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain LRR_6 PF13516.6 ORX86238.1 - 1.6e-12 46.4 3.9 0.00015 21.5 0.5 5.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 ORX86238.1 - 8.9e-06 26.0 4.4 0.54 10.8 0.1 4.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Recep_L_domain PF01030.24 ORX86238.1 - 0.016 15.3 0.2 2.8 8.1 0.0 3.4 1 1 2 3 3 3 0 Receptor L domain LRR_1 PF00560.33 ORX86238.1 - 0.056 14.0 4.5 21 6.1 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat Pro_isomerase PF00160.21 ORX86239.1 - 8.1e-48 162.7 0.1 1.2e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORX86239.1 - 2.1e-19 69.1 0.0 3.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX86239.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX86239.1 - 0.04 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 ORX86239.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 CBS PF00571.28 ORX86240.1 - 1.7e-08 34.8 0.4 2.4e-05 24.7 0.1 2.8 2 2 1 3 3 3 2 CBS domain GPAT_N PF14829.6 ORX86240.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal PocR PF10114.9 ORX86241.1 - 0.42 10.4 4.2 4.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Sensory domain found in PocR PocR PF10114.9 ORX86242.1 - 0.31 10.8 3.9 4.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Sensory domain found in PocR PocR PF10114.9 ORX86243.1 - 0.4 10.4 4.2 4.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Sensory domain found in PocR PocR PF10114.9 ORX86244.1 - 0.31 10.8 3.9 4.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Sensory domain found in PocR DNA_binding_1 PF01035.20 ORX86307.1 - 6.1e-23 80.8 0.0 8e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ArfGap PF01412.18 ORX86308.1 - 1.4e-35 121.9 0.0 1.4e-35 121.9 0.0 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 ORX86308.1 - 6.5e-18 65.3 18.3 1.3e-17 64.3 18.3 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORX86308.1 - 4.3e-10 40.0 0.3 4.3e-10 40.0 0.3 2.3 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 ORX86308.1 - 1.5e-07 31.9 0.0 1.6e-06 28.6 0.0 2.5 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX86308.1 - 4.6e-07 30.3 0.0 2.1e-05 25.0 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX86308.1 - 7.3e-05 22.9 0.0 0.083 13.5 0.0 3.8 4 0 0 4 4 3 1 Ankyrin repeat Ank_5 PF13857.6 ORX86308.1 - 0.00035 20.8 0.0 0.00086 19.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORX86308.1 - 0.00073 19.9 0.0 0.02 15.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat DDE_1 PF03184.19 ORX86308.1 - 0.023 14.3 1.0 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease CdvA PF18822.1 ORX86308.1 - 0.42 10.4 8.9 0.3 10.9 3.9 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Syntaxin_2 PF14523.6 ORX86308.1 - 2.8 8.3 7.5 3.3 8.1 0.7 3.0 2 0 0 2 2 2 0 Syntaxin-like protein FadA PF09403.10 ORX86308.1 - 4.2 7.9 12.6 0.84 10.2 2.8 2.9 2 0 0 2 2 2 0 Adhesion protein FadA Rad60-SLD PF11976.8 ORX86309.1 - 0.00015 21.5 2.1 0.00039 20.2 2.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORX86309.1 - 0.00093 18.9 1.3 0.0023 17.6 1.3 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF866 PF05907.13 ORX86309.1 - 0.02 14.8 0.4 0.022 14.7 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF4120 PF13496.6 ORX86309.1 - 0.15 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) MgtE PF01769.16 ORX86310.1 - 3e-22 79.3 4.6 3e-22 79.3 4.6 1.8 2 0 0 2 2 2 1 Divalent cation transporter Tmemb_170 PF10190.9 ORX86311.1 - 1.2e-21 77.1 15.8 1.5e-21 76.7 15.8 1.2 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1129 PF06570.11 ORX86311.1 - 0.75 9.2 6.7 0.95 8.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MIR PF02815.19 ORX86312.1 - 2.8e-14 53.4 0.7 5.9e-06 26.3 0.1 3.1 1 1 2 3 3 3 3 MIR domain Mucin_bdg PF03272.13 ORX86312.1 - 0.12 12.4 0.1 1.5 8.9 0.0 2.3 3 0 0 3 3 3 0 Putative mucin or carbohydrate-binding module Chitin_synth_2 PF03142.15 ORX86313.1 - 6e-240 797.3 2.2 8.8e-240 796.8 1.7 1.5 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 ORX86313.1 - 1.9e-140 469.3 0.1 2.6e-140 468.8 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORX86313.1 - 1.1e-17 63.7 0.0 4.8e-17 61.6 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORX86313.1 - 4.3e-11 43.2 0.0 3.5e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX86313.1 - 6.7e-09 35.9 3.3 6.7e-09 35.9 3.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 ORX86313.1 - 3.7e-06 27.0 0.7 0.0075 16.4 0.1 3.3 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORX86313.1 - 0.00073 19.4 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Wzy_C PF04932.15 ORX86313.1 - 0.031 13.9 0.2 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 O-Antigen ligase AAA_16 PF13191.6 ORX86313.1 - 0.062 13.7 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Glyco_transf_21 PF13506.6 ORX86313.1 - 0.085 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 T2SSE PF00437.20 ORX86313.1 - 0.19 10.7 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 ORX86314.1 - 2.9e-43 147.5 0.0 4.7e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX86314.1 - 6.3e-14 51.5 0.1 1.4e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORX86314.1 - 4.1e-11 42.6 0.6 1.1e-10 41.2 0.0 2.1 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 ORX86314.1 - 1.3e-07 32.2 0.0 7.1e-05 23.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORX86314.1 - 8.5e-07 29.0 0.1 1.9e-05 24.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORX86314.1 - 3.2e-06 27.3 0.0 8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORX86314.1 - 6.5e-06 26.0 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX86314.1 - 0.00022 21.5 0.1 0.0066 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX86314.1 - 0.00053 20.5 0.2 0.0026 18.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 ORX86314.1 - 0.00073 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORX86314.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 ORX86314.1 - 0.002 17.4 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ORX86314.1 - 0.003 17.0 0.0 0.0089 15.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORX86314.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 ORX86314.1 - 0.0051 16.8 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ORX86314.1 - 0.0056 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 ORX86314.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ORX86314.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORX86314.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Thymidylate_kin PF02223.17 ORX86314.1 - 0.013 15.1 0.1 3.7 7.2 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase AAA_3 PF07726.11 ORX86314.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 ORX86314.1 - 0.026 14.2 0.1 0.099 12.3 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 ORX86314.1 - 0.027 14.2 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORX86314.1 - 0.04 13.7 0.4 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORX86314.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORX86314.1 - 0.055 12.8 0.7 0.17 11.2 0.0 2.1 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 ORX86314.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 ORX86314.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 ORX86314.1 - 0.071 12.7 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX86314.1 - 0.079 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORX86314.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 ORX86314.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase PF00069.25 ORX86315.1 - 9.4e-53 179.2 0.0 1.5e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX86315.1 - 9.8e-21 74.2 0.0 1.7e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX86315.1 - 1.2e-05 24.7 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX86315.1 - 0.00018 20.9 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX86315.1 - 0.00064 18.8 0.2 0.00064 18.8 0.2 1.7 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 ORX86315.1 - 0.00089 18.9 0.3 0.12 12.0 0.0 2.6 1 1 2 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORX86315.1 - 0.026 13.3 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORX86315.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_38N PF01074.22 ORX86316.1 - 7.5e-90 301.2 0.2 1.4e-89 300.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORX86316.1 - 3.7e-58 197.1 0.0 5.8e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORX86316.1 - 1.5e-28 98.8 0.0 4.6e-28 97.2 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORX86316.1 - 4e-13 49.3 0.0 8.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORX86316.1 - 0.0025 17.1 0.1 0.0074 15.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Cyclin_N PF00134.23 ORX86317.1 - 1.1e-09 38.1 0.1 1.3e-09 37.8 0.1 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX86317.1 - 0.0012 19.2 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin MSC PF09402.10 ORX86386.1 - 3.7e-78 263.3 0.3 4.9e-78 262.9 0.3 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORX86386.1 - 4.8e-12 45.4 0.0 4.8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 HeH/LEM domain UPF0183 PF03676.14 ORX86387.1 - 1.7e-104 350.2 0.0 2.5e-104 349.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) RhoGAP PF00620.27 ORX86387.1 - 1.3e-36 125.8 0.0 2.7e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MIF4G PF02854.19 ORX86388.1 - 2.8e-58 197.1 3.6 3.3e-58 196.8 3.6 1.1 1 0 0 1 1 1 1 MIF4G domain Vpu PF00558.19 ORX86388.1 - 0.068 12.9 0.7 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Vpu protein DUF5314 PF17241.2 ORX86388.1 - 0.11 12.1 2.3 0.091 12.4 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5314) PB1 PF00564.24 ORX86389.1 - 4.1e-13 49.1 0.9 7.2e-13 48.3 0.9 1.4 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 ORX86389.1 - 2.2e-11 43.1 5.9 0.0055 16.5 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX86389.1 - 1.6e-07 30.9 8.1 0.27 11.4 0.2 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX86389.1 - 3.2e-06 26.9 6.1 0.12 12.7 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX86389.1 - 0.00061 20.0 2.1 0.037 14.3 0.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX86389.1 - 0.12 13.1 3.6 34 5.4 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX86389.1 - 0.12 12.1 2.6 0.45 10.2 0.1 3.1 2 1 1 3 3 3 0 TPR repeat TPR_7 PF13176.6 ORX86389.1 - 0.14 12.2 1.8 2.8 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORX86389.1 - 4.5 8.0 7.4 2.1 9.0 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 ORX86390.1 - 1.1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 ORX86390.1 - 2.7e-08 33.1 1.4 4e-06 25.9 0.1 3.0 1 1 2 3 3 3 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 ORX86390.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking KH_dom-like PF14714.6 ORX86390.1 - 0.13 12.5 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Med14 PF08638.11 ORX86392.1 - 1.8e-65 219.9 0.4 5.4e-65 218.4 0.2 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 Pterin_bind PF00809.22 ORX86393.1 - 1.8e-84 283.2 0.0 2.9e-84 282.6 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 ORX86393.1 - 5.1e-53 178.3 0.3 2.3e-25 89.3 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 ORX86393.1 - 6.3e-38 129.7 0.0 4.4e-37 127.0 0.0 2.4 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) QRPTase_C PF01729.19 ORX86393.1 - 0.091 12.5 0.2 0.38 10.5 0.2 2.1 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain BTB PF00651.31 ORX86394.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PH PF00169.29 ORX86395.1 - 1e-14 54.9 0.1 3.8e-12 46.6 0.1 2.5 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 ORX86395.1 - 2.1e-09 37.6 0.2 5.2e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 ORX86395.1 - 0.0045 17.3 0.3 0.016 15.6 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 ORX86395.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 ORX86395.1 - 0.2 12.1 0.6 0.78 10.2 0.6 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain ERG4_ERG24 PF01222.17 ORX86396.1 - 1.9e-149 498.1 16.9 2.2e-149 497.9 16.9 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORX86396.1 - 3.2e-05 23.6 2.1 7.2e-05 22.4 2.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PRCH PF03967.13 ORX86396.1 - 0.3 11.3 1.4 0.99 9.6 0.0 2.1 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region Ferrochelatase PF00762.19 ORX86397.1 - 1.9e-109 365.6 0.0 2.2e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 ORX86397.1 - 0.0022 18.3 0.0 3.3 8.1 0.0 2.6 2 0 0 2 2 2 2 CbiX DAO PF01266.24 ORX86398.1 - 2.1e-51 175.6 0.5 3.1e-51 175.0 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX86398.1 - 0.00016 21.0 4.7 0.0087 15.3 1.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX86398.1 - 0.00045 19.5 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORX86398.1 - 0.0009 19.4 0.1 0.0025 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 ORX86398.1 - 0.0035 16.0 0.0 0.18 10.3 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 ORX86398.1 - 0.009 15.1 0.4 0.018 14.2 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 ORX86398.1 - 0.048 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORX86398.1 - 0.078 13.2 0.6 0.18 12.0 0.3 1.8 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 ORX86398.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_3 PF07859.13 ORX86399.1 - 9.2e-27 94.3 0.1 1.2e-26 93.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX86399.1 - 7.3e-05 21.8 0.0 0.0001 21.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 ORX86399.1 - 0.057 13.1 0.1 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Hydrolase_4 PF12146.8 ORX86399.1 - 0.099 11.9 0.0 3.7 6.7 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 RRM_1 PF00076.22 ORX86477.1 - 4.9e-82 269.7 1.9 4.5e-20 71.3 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORX86477.1 - 1.7e-28 98.6 0.5 8.7e-28 96.3 0.7 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORX86477.1 - 2.6e-11 43.2 0.2 0.013 15.1 0.0 4.1 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX86477.1 - 0.00015 21.5 0.0 0.04 13.8 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_8 PF11835.8 ORX86477.1 - 0.0004 20.5 0.0 0.1 12.9 0.0 3.2 3 0 0 3 3 3 1 RRM-like domain RRM_7 PF16367.5 ORX86477.1 - 0.0019 18.3 0.5 9.4 6.4 0.0 4.8 3 1 1 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ORX86477.1 - 0.0024 17.8 0.3 8.5 6.5 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif YflT PF11181.8 ORX86477.1 - 0.0092 16.5 3.6 0.54 10.8 2.8 3.1 3 0 0 3 3 3 1 Heat induced stress protein YflT RRM_3 PF08777.11 ORX86477.1 - 0.011 15.8 7.8 3.7 7.6 3.4 3.9 3 1 1 4 4 4 0 RNA binding motif SET_assoc PF11767.8 ORX86477.1 - 0.013 15.2 0.2 14 5.4 0.0 4.0 4 1 0 4 4 4 0 Histone lysine methyltransferase SET associated Fumble PF03630.14 ORX86478.1 - 5e-113 377.6 1.8 5.7e-113 377.4 1.8 1.0 1 0 0 1 1 1 1 Fumble PDZ_5 PF17817.1 ORX86479.1 - 0.028 14.7 0.2 0.049 13.9 0.2 1.4 1 0 0 1 1 1 0 PDZ domain Spc7 PF08317.11 ORX86480.1 - 0.023 13.6 29.6 0.095 11.6 19.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1192 PF06698.11 ORX86480.1 - 0.086 12.9 3.2 0.087 12.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Type2_restr_D3 PF16902.5 ORX86480.1 - 0.12 12.3 1.1 3.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain NPV_P10 PF05531.12 ORX86480.1 - 0.64 10.5 14.9 3.3 8.2 2.1 4.2 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein GlcNAc-1_reg PF18440.1 ORX86480.1 - 3.9 7.8 6.1 1.3 9.3 0.2 2.8 2 1 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain GAS PF13851.6 ORX86480.1 - 7 6.0 32.3 1.6 8.0 6.7 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding RRM_1 PF00076.22 ORX86482.1 - 4.5e-17 61.6 0.0 6.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORX86482.1 - 6.5e-08 33.0 8.4 6.5e-08 33.0 8.4 2.4 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Btz PF09405.10 ORX86482.1 - 0.0089 16.3 1.7 0.0089 16.3 1.7 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RNase_H PF00075.24 ORX86483.1 - 1.2e-38 132.5 0.2 2.6e-38 131.4 0.2 1.5 1 0 0 1 1 1 1 RNase H TPR_1 PF00515.28 ORX86484.1 - 7.3e-55 180.7 12.8 9.6e-09 34.7 0.1 10.6 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORX86484.1 - 1.5e-46 152.8 8.8 3.4e-06 26.7 0.1 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 ORX86484.1 - 4.7e-38 126.2 8.1 1e-05 25.4 0.0 10.4 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_11 PF13414.6 ORX86484.1 - 5.1e-24 83.7 19.3 5.5e-08 32.4 1.1 8.8 7 4 2 9 9 9 4 TPR repeat TPR_14 PF13428.6 ORX86484.1 - 8.5e-24 82.2 6.5 0.00039 21.0 0.0 8.4 5 3 5 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORX86484.1 - 1.4e-21 76.6 22.0 4.7e-05 23.6 1.6 8.2 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORX86484.1 - 3e-21 75.8 1.5 8.1e-06 26.4 0.1 6.8 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORX86484.1 - 3.8e-21 75.4 5.5 0.0014 19.1 0.1 6.9 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORX86484.1 - 1.8e-19 68.6 11.7 0.022 15.1 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 ORX86484.1 - 7.4e-18 64.5 5.6 0.00036 20.6 0.1 6.2 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORX86484.1 - 4.7e-16 58.3 5.3 0.22 12.2 0.1 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORX86484.1 - 5.5e-16 57.4 12.1 0.31 11.2 0.1 8.8 8 2 1 9 9 8 4 Tetratricopeptide repeat SNAP PF14938.6 ORX86484.1 - 1.4e-06 28.0 9.5 0.033 13.6 1.8 4.7 2 2 2 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 ORX86484.1 - 4.5e-06 26.1 9.7 0.27 10.4 0.4 5.2 1 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX86484.1 - 1.8e-05 24.4 11.7 7.3 6.6 0.1 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX86484.1 - 4.1e-05 23.7 13.4 7.4e-05 22.9 3.0 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 ORX86484.1 - 0.00017 22.0 6.4 0.47 10.9 0.0 3.5 2 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_21 PF09976.9 ORX86484.1 - 0.00022 21.0 6.6 1.8 8.2 0.0 4.9 2 2 1 4 4 4 1 Tetratricopeptide repeat-like domain MIT PF04212.18 ORX86484.1 - 0.00087 19.3 7.9 9.3 6.4 0.2 6.6 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 ORX86484.1 - 0.0084 15.2 0.6 0.46 9.4 0.2 2.7 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 ORX86484.1 - 0.011 15.8 0.7 56 3.9 0.0 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 ORX86484.1 - 0.04 13.9 2.8 1.8 8.6 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF627) PknG_TPR PF16918.5 ORX86484.1 - 0.059 12.1 0.0 0.24 10.1 0.0 2.0 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat Coatomer_WDAD PF04053.14 ORX86484.1 - 0.23 10.5 3.2 1.1 8.3 0.1 3.2 5 0 0 5 5 5 0 Coatomer WD associated region TPR_3 PF07720.12 ORX86484.1 - 0.51 10.4 17.3 1.2 9.2 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-CCCH PF00642.24 ORX86485.1 - 7.6e-13 48.0 16.3 3.6e-07 29.9 2.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORX86485.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 ORX86485.1 - 0.00055 20.6 2.4 0.13 13.0 0.2 2.5 3 0 0 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 ORX86485.1 - 0.0008 19.6 6.0 0.088 13.0 0.4 2.2 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 ORX86485.1 - 0.011 15.8 2.9 0.011 15.8 2.9 2.7 2 0 0 2 2 2 0 Zinc finger domain Peptidase_M16_C PF05193.21 ORX86485.1 - 0.099 12.6 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M16 inactive domain Pex14_N PF04695.13 ORX86486.1 - 9.8e-22 78.3 1.2 9.8e-22 78.3 1.2 2.7 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 ORX86486.1 - 0.043 13.9 0.4 0.086 12.9 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 ORX86486.1 - 0.06 13.5 1.1 0.12 12.5 1.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 ORX86486.1 - 0.065 13.6 2.4 0.19 12.0 1.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Retrotrans_gag PF03732.17 ORX86486.1 - 0.12 12.6 3.7 0.74 10.1 0.6 2.9 2 1 0 2 2 2 0 Retrotransposon gag protein XhlA PF10779.9 ORX86486.1 - 0.14 12.3 0.3 0.78 10.0 0.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Allexi_40kDa PF05549.11 ORX86486.1 - 1.2 8.6 6.2 0.14 11.6 1.4 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF4795 PF16043.5 ORX86486.1 - 1.3 8.6 8.1 0.093 12.3 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) PCRF PF03462.18 ORX86486.1 - 1.7 8.5 5.2 0.34 10.7 1.5 1.7 2 0 0 2 2 2 0 PCRF domain CLZ PF16526.5 ORX86486.1 - 2.1 8.8 5.2 15 6.0 0.4 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKA1 PF07160.12 ORX86486.1 - 5.6 6.7 8.6 1.2 9.0 0.9 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SHE3 PF17078.5 ORX86486.1 - 6.9 6.3 9.9 0.88 9.2 2.2 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 AMP-binding PF00501.28 ORX86487.1 - 2e-105 352.9 0.1 2.6e-105 352.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX86487.1 - 0.021 15.8 0.1 0.17 12.8 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain SRP19 PF01922.17 ORX86488.1 - 9.8e-29 100.2 0.0 1.7e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein zf-MYND PF01753.18 ORX86490.1 - 6.9e-08 32.5 15.0 1.3e-07 31.5 15.0 1.5 1 0 0 1 1 1 1 MYND finger MFS_1 PF07690.16 ORX86491.1 - 5e-31 107.9 25.7 8.9e-28 97.2 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX86491.1 - 1.1e-13 50.9 8.7 1.1e-13 50.9 8.7 2.6 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 ORX86491.1 - 0.0035 16.7 2.7 0.0035 16.7 2.7 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ORX86491.1 - 0.31 9.4 11.5 0.11 10.9 0.9 2.5 3 0 0 3 3 3 0 Transmembrane secretion effector NUFIP1 PF10453.9 ORX86563.1 - 3.2e-15 55.7 6.5 3.2e-15 55.7 6.5 1.9 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 ORX86563.1 - 6.2e-07 29.2 6.2 1.4e-06 28.1 6.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX86563.1 - 9.6e-07 28.7 9.2 2.1e-06 27.6 9.2 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 ORX86563.1 - 1.1e-06 29.3 3.5 1.1e-06 29.3 3.5 2.3 2 1 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 ORX86563.1 - 1.4e-05 24.8 8.7 2.6e-05 23.9 8.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORX86563.1 - 0.24 11.9 6.4 0.49 10.9 6.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 ORX86563.1 - 4.6 7.1 9.3 0.075 12.8 2.2 1.8 2 0 0 2 2 2 0 Putative zinc-finger domain PGI PF00342.19 ORX86564.1 - 1.7e-229 762.4 5.6 7.7e-116 387.6 1.1 2.1 1 1 1 2 2 2 2 Phosphoglucose isomerase CDC37_N PF03234.14 ORX86565.1 - 2.2e-37 128.8 2.6 2.2e-37 128.8 2.6 2.6 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 ORX86565.1 - 4.5e-29 100.8 1.0 8.1e-29 99.9 0.1 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain Syntaxin_2 PF14523.6 ORX86565.1 - 0.0042 17.4 7.5 0.0052 17.1 1.3 2.4 2 0 0 2 2 2 1 Syntaxin-like protein DUF4407 PF14362.6 ORX86565.1 - 0.76 9.1 4.0 0.14 11.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HTH_25 PF13413.6 ORX86565.1 - 0.95 9.4 4.3 72 3.4 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain EF_TS PF00889.19 ORX86566.1 - 5.7e-29 101.2 0.0 5.5e-22 78.4 0.0 2.5 1 1 1 2 2 2 2 Elongation factor TS HBS1_N PF08938.10 ORX86566.1 - 0.0058 16.9 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus UBA PF00627.31 ORX86566.1 - 0.12 12.3 0.8 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 UBA/TS-N domain DUF2853 PF11015.8 ORX86566.1 - 0.12 13.0 0.0 1.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Response_reg PF00072.24 ORX86567.1 - 4e-52 175.1 0.4 8.6e-25 87.1 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX86567.1 - 2.1e-48 163.5 0.0 7.4e-23 81.2 0.3 2.8 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX86567.1 - 1.2e-23 82.9 2.1 1.2e-14 54.1 0.1 3.1 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX86567.1 - 1.3e-10 41.4 0.3 3.7e-10 40.0 0.3 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORX86567.1 - 5.8e-08 32.7 0.2 2.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 ORX86567.1 - 1.1e-06 28.5 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 ORX86567.1 - 0.00011 22.4 0.1 0.00061 20.0 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX86567.1 - 0.00017 21.8 0.0 0.00061 20.0 0.0 2.0 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.6 ORX86567.1 - 0.0038 17.6 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ORX86567.1 - 0.0089 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.24 ORX86568.1 - 1.8e-52 176.3 0.3 5.7e-25 87.7 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX86568.1 - 1.6e-50 170.3 0.7 2.7e-24 85.8 0.3 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX86568.1 - 1.6e-23 82.5 2.0 1.6e-14 53.6 0.1 3.1 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX86568.1 - 4.6e-09 36.5 0.2 1.4e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORX86568.1 - 3.2e-07 30.3 0.2 3e-06 27.2 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 ORX86568.1 - 1.2e-06 28.8 0.0 0.018 15.3 0.0 3.4 3 1 1 4 4 4 2 PAS fold HATPase_c_3 PF13589.6 ORX86568.1 - 1.2e-06 28.4 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 ORX86568.1 - 8e-05 22.8 0.2 0.003 17.8 0.0 3.3 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 ORX86568.1 - 0.00025 21.0 0.0 0.014 15.4 0.0 3.2 3 0 0 3 3 3 1 PAS domain GAF_2 PF13185.6 ORX86568.1 - 0.0036 17.6 0.0 0.073 13.4 0.0 2.5 2 0 0 2 2 2 1 GAF domain Prefoldin_2 PF01920.20 ORX86568.1 - 0.013 15.4 0.0 0.013 15.4 0.0 2.7 3 0 0 3 3 2 0 Prefoldin subunit GAF_3 PF13492.6 ORX86568.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 GAF domain Response_reg PF00072.24 ORX86569.1 - 4.5e-52 175.0 0.2 1e-24 86.8 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX86569.1 - 7.2e-48 161.7 3.8 2e-23 83.1 0.3 3.6 3 1 0 3 3 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX86569.1 - 3e-23 81.6 2.0 2.1e-14 53.3 0.1 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX86569.1 - 1.2e-09 38.3 0.2 5.4e-09 36.2 0.2 2.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORX86569.1 - 3.7e-07 30.0 0.0 0.028 14.5 0.0 4.1 4 0 0 4 4 4 2 PAS domain PAS_9 PF13426.7 ORX86569.1 - 6.6e-07 29.5 0.3 0.0064 16.7 0.0 4.1 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 ORX86569.1 - 9.4e-07 29.1 0.0 0.33 11.2 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS PF00989.25 ORX86569.1 - 1.5e-06 28.2 0.7 5.3e-05 23.2 0.0 3.4 4 0 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.6 ORX86569.1 - 1.6e-06 28.0 0.1 0.017 14.9 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prefoldin_2 PF01920.20 ORX86569.1 - 0.013 15.4 0.0 0.013 15.4 0.0 3.3 4 0 0 4 4 3 0 Prefoldin subunit GAF_2 PF13185.6 ORX86569.1 - 0.017 15.4 0.0 0.098 12.9 0.0 2.2 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 ORX86569.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 GAF domain DPPIV_rep PF18811.1 ORX86569.1 - 0.58 10.2 1.9 1.6 8.8 1.9 1.8 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Response_reg PF00072.24 ORX86570.1 - 1.9e-52 176.1 0.4 4.3e-25 88.0 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX86570.1 - 1.4e-47 160.8 0.8 1.7e-22 80.0 0.3 3.3 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX86570.1 - 1.9e-23 82.2 2.3 1.7e-14 53.6 0.2 3.4 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX86570.1 - 9.6e-12 45.0 0.5 4.3e-11 42.9 0.3 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ORX86570.1 - 5.1e-10 39.6 0.0 8.6e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORX86570.1 - 3.2e-08 33.5 0.2 1.3e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 ORX86570.1 - 1.9e-06 27.8 0.1 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 ORX86570.1 - 1e-05 25.7 0.0 0.00017 21.8 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 ORX86570.1 - 0.0038 17.2 0.0 0.021 14.8 0.0 2.2 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.6 ORX86570.1 - 0.08 13.2 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 GAF domain Response_reg PF00072.24 ORX86571.1 - 6.2e-53 177.7 0.2 3.7e-25 88.3 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORX86571.1 - 4.6e-48 162.4 0.8 1.6e-22 80.1 0.3 3.1 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORX86571.1 - 2.3e-23 82.0 2.7 1.6e-14 53.6 0.2 3.3 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ORX86571.1 - 2.6e-11 43.7 0.8 1e-10 41.7 0.4 2.4 2 0 0 2 2 1 1 PAS fold PAS_4 PF08448.10 ORX86571.1 - 2.1e-10 40.8 0.0 4.1e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 PAS fold HATPase_c_3 PF13589.6 ORX86571.1 - 1.6e-06 28.0 0.2 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ORX86571.1 - 1.7e-06 28.0 0.0 5.6e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORX86571.1 - 0.0021 18.3 0.0 0.048 13.9 0.0 3.2 3 0 0 3 3 3 1 PAS domain DUF866 PF05907.13 ORX86571.1 - 0.0026 17.7 1.9 0.0068 16.3 1.9 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) GAF_3 PF13492.6 ORX86571.1 - 0.0063 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ORX86571.1 - 0.009 16.3 0.0 0.067 13.5 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 ORX86571.1 - 0.15 12.1 0.0 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain Peptidase_S9 PF00326.21 ORX86572.1 - 9.7e-58 195.1 0.7 1.7e-57 194.3 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORX86572.1 - 1.6e-08 34.2 9.9 0.14 12.1 0.1 5.4 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 ORX86572.1 - 1.9e-05 24.4 0.7 0.058 13.0 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORX86572.1 - 0.00042 19.1 0.1 0.0048 15.6 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ORX86572.1 - 0.011 15.2 0.0 0.031 13.8 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2920 PF11144.8 ORX86572.1 - 0.041 13.0 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.8 ORX86572.1 - 0.088 12.1 0.0 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PUF PF00806.19 ORX86626.1 - 3e-58 190.4 7.1 4.9e-08 32.2 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat UCR_TM PF02921.14 ORX86627.1 - 5.4e-12 46.0 0.7 5.4e-12 46.0 0.7 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 ORX86627.1 - 8.3e-11 41.7 0.1 1.5e-10 40.8 0.1 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain SUKH-4 PF14435.6 ORX86627.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein SUI1 PF01253.22 ORX86629.1 - 4.1e-20 72.1 1.7 5.3e-20 71.7 0.4 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 ORX86629.1 - 0.091 13.1 0.2 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Tyrosinase PF00264.20 ORX86630.1 - 5e-37 128.3 5.2 3.2e-36 125.7 5.2 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF496 PF04363.12 ORX86631.1 - 0.044 13.8 0.1 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF496) APG12 PF04110.13 ORX86631.1 - 0.14 12.6 0.0 0.46 10.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 ubiquitin PF00240.23 ORX86632.1 - 1.4e-69 229.8 7.5 2.3e-34 117.0 0.9 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 ORX86632.1 - 6.6e-33 112.4 8.0 4.6e-16 58.4 1.0 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORX86632.1 - 3.3e-13 49.9 2.5 4.3e-05 23.9 0.2 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 ORX86632.1 - 1.2e-08 34.7 0.7 0.005 16.8 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORX86632.1 - 2.2e-08 34.3 1.0 0.0068 16.7 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORX86632.1 - 3.5e-08 33.5 0.5 0.014 15.5 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORX86632.1 - 1.7e-07 31.7 0.1 0.025 15.1 0.0 2.1 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORX86632.1 - 1.4e-05 25.0 0.1 0.13 12.1 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 ORX86632.1 - 2.1e-05 24.5 8.9 3.7 7.7 0.2 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain DUF3861 PF12977.7 ORX86632.1 - 0.0015 18.7 0.4 1.7 8.9 0.0 2.2 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) DUF1940 PF09155.10 ORX86632.1 - 0.013 15.6 0.5 5.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) ACT_5 PF13710.6 ORX86632.1 - 0.015 15.2 0.8 5.6 6.9 0.1 2.4 2 0 0 2 2 2 0 ACT domain DUF2870 PF11069.8 ORX86632.1 - 0.016 15.5 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) TmoB PF06234.12 ORX86632.1 - 0.026 14.6 0.6 11 6.2 0.1 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) DUF493 PF04359.14 ORX86632.1 - 0.044 14.4 0.0 16 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Big_3_3 PF13750.6 ORX86632.1 - 0.045 13.4 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Raf1_HTH PF18579.1 ORX86632.1 - 0.052 13.2 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Big_7 PF17957.1 ORX86632.1 - 0.07 13.9 0.0 21 6.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain PI3K_p85B PF02192.16 ORX86632.1 - 0.17 11.7 1.9 14 5.5 0.1 2.3 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Tash_PEST PF07708.11 ORX86632.1 - 0.18 12.0 9.6 2.7 8.2 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif ProRS-C_2 PF09181.10 ORX86632.1 - 0.21 11.8 0.6 27 5.0 0.1 2.2 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal FERM_f0 PF16511.5 ORX86632.1 - 0.23 11.8 2.2 35 4.8 0.1 3.3 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Plexin_cytopl PF08337.12 ORX86632.1 - 0.49 9.0 7.1 3.8 6.1 0.8 2.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Adaptin_binding PF10199.9 ORX86633.1 - 5.1e-14 52.9 3.3 8.8e-14 52.2 3.3 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF815 PF05673.13 ORX86633.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Roc PF08477.13 ORX86633.1 - 0.017 15.4 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Bac_DnaA PF00308.18 ORX86633.1 - 0.03 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 ORX86633.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Ras PF00071.22 ORX86633.1 - 0.063 12.9 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 Ras family AAA_7 PF12775.7 ORX86633.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 ORX86633.1 - 0.12 12.9 0.2 0.86 10.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA PF00004.29 ORX86633.1 - 0.15 12.5 0.1 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) F-box-like PF12937.7 ORX86634.1 - 2.5e-06 27.3 0.1 8.3e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like RsbU_N PF08673.10 ORX86634.1 - 0.077 13.1 0.7 0.25 11.5 0.7 1.9 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF3557 PF12078.8 ORX86634.1 - 9.4 6.2 9.7 1.2 9.0 1.9 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3557) WD40 PF00400.32 ORX86636.1 - 2e-15 56.9 16.1 0.0012 19.6 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX86636.1 - 2.9e-09 37.1 2.3 4.9e-05 23.6 0.6 5.1 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX86636.1 - 5.2e-06 25.4 0.5 0.00012 20.9 0.3 2.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORX86636.1 - 0.0012 17.7 0.0 0.28 9.9 0.0 3.0 1 1 1 3 3 3 1 Nup133 N terminal like Histone PF00125.24 ORX86637.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX86637.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX86637.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORX86637.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORX86637.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX86637.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX86637.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated GTP_EFTU PF00009.27 ORX86638.1 - 9.1e-59 198.3 0.0 1.8e-58 197.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORX86638.1 - 1.5e-10 41.0 0.0 4.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORX86638.1 - 4.6e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORX86638.1 - 3.8e-08 33.3 0.3 1e-07 31.9 0.1 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 ORX86638.1 - 0.00024 20.9 0.0 0.071 12.9 0.0 3.1 2 1 1 3 3 3 1 Elongation factor G, domain IV G-alpha PF00503.20 ORX86638.1 - 0.0074 15.5 0.2 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit D123 PF07065.14 ORX86638.1 - 0.037 13.2 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 D123 RsgA_GTPase PF03193.16 ORX86638.1 - 0.28 11.1 1.4 0.7 9.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF4506 PF14958.6 ORX86639.1 - 0.0011 18.4 0.1 0.0056 16.2 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4506) STN1_2 PF09170.10 ORX86640.1 - 6.1e-14 52.6 0.4 1.4e-13 51.5 0.4 1.6 1 1 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Linker_histone PF00538.19 ORX86640.1 - 0.03 14.7 0.2 17 5.8 0.0 3.0 4 0 0 4 4 4 0 linker histone H1 and H5 family RabGAP-TBC PF00566.18 ORX86641.1 - 8.9e-41 139.9 2.2 1.8e-40 138.9 2.2 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Thymidylat_synt PF00303.19 ORX86642.1 - 4.8e-111 370.2 0.0 5.4e-111 370.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase LETM1 PF07766.13 ORX86643.1 - 5.5e-101 337.4 6.1 7e-101 337.1 6.1 1.1 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 ORX86643.1 - 0.012 15.3 0.0 8.9 6.2 0.0 2.8 2 0 0 2 2 2 0 SAP domain Nuf2 PF03800.14 ORX86644.1 - 1e-43 148.8 0.8 1e-43 148.8 0.8 2.4 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 ORX86644.1 - 4e-26 91.4 20.1 4e-26 91.4 20.1 4.0 2 2 2 4 4 4 2 Designed helical repeat protein 10 domain Cortex-I_coil PF09304.10 ORX86644.1 - 0.0022 18.2 2.9 0.0022 18.2 2.9 3.7 1 1 0 3 3 3 1 Cortexillin I, coiled coil DUF4200 PF13863.6 ORX86644.1 - 0.005 17.2 57.9 0.038 14.4 20.6 4.6 1 1 3 4 4 4 2 Domain of unknown function (DUF4200) HrpB7 PF09486.10 ORX86644.1 - 0.0071 16.7 0.9 0.0071 16.7 0.9 4.0 2 2 1 3 3 3 1 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 ORX86644.1 - 0.012 15.7 51.8 0.041 13.9 2.7 4.8 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 ORX86644.1 - 0.21 10.4 49.9 0.29 10.0 13.9 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 ORX86644.1 - 0.35 10.2 53.9 1.4 8.2 24.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 ORX86644.1 - 1.2 9.5 40.5 0.38 11.1 1.1 5.3 1 1 5 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 ORX86644.1 - 1.4 9.0 52.6 1.1 9.2 19.7 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 ORX86644.1 - 1.9 8.2 46.6 0.65 9.8 18.6 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 ORX86644.1 - 3.1 7.9 53.4 1.7 8.8 11.6 3.7 2 2 1 3 3 3 0 Tropomyosin like SLATT_5 PF18160.1 ORX86644.1 - 4.5 6.5 14.2 0.91 8.8 0.1 3.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4407 PF14362.6 ORX86644.1 - 8.9 5.6 35.2 2.6 7.3 8.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 ORX86644.1 - 9.1 5.5 44.0 2.4 7.4 10.3 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 ORX86644.1 - 9.4 3.6 41.1 1.4e+04 -6.9 41.1 2.5 1 1 0 1 1 0 0 Protein of unknown function (DUF3584) HAMP PF00672.25 ORX86645.1 - 8.2e-170 551.2 33.7 3.2e-08 33.8 0.0 22.2 21 0 0 21 21 21 20 HAMP domain HATPase_c PF02518.26 ORX86645.1 - 1.3e-28 99.8 0.2 4.9e-28 97.9 0.2 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APG17 PF04108.12 ORX86645.1 - 9e-28 97.5 25.7 0.0014 17.8 4.9 10.3 1 1 7 11 11 11 10 Autophagy protein Apg17 HMG_box PF00505.19 ORX86645.1 - 2.1e-25 88.9 1.8 20 5.7 0.0 17.0 17 0 0 17 17 17 0 HMG (high mobility group) box Response_reg PF00072.24 ORX86645.1 - 2.1e-25 89.1 0.5 1.3e-24 86.6 0.5 2.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF4279 PF14106.6 ORX86645.1 - 1.9e-19 70.0 0.0 12 6.1 0.0 17.4 20 0 0 20 20 20 0 Domain of unknown function (DUF4279) HTH_6 PF01418.17 ORX86645.1 - 3.1e-18 65.5 1.8 15 5.7 0.0 16.2 16 0 0 16 16 16 0 Helix-turn-helix domain, rpiR family WXG100 PF06013.12 ORX86645.1 - 2.3e-17 63.0 56.1 1.7 8.9 0.1 20.8 20 2 1 22 22 22 4 Proteins of 100 residues with WXG HisKA PF00512.25 ORX86645.1 - 7.2e-17 61.2 1.9 4e-16 58.8 0.3 3.5 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain Focal_AT PF03623.13 ORX86645.1 - 2.6e-13 50.1 46.3 13 5.8 0.1 17.8 3 2 6 17 17 17 0 Focal adhesion targeting region SpoIIID PF12116.8 ORX86645.1 - 2.7e-10 40.2 35.9 21 5.3 0.0 16.9 18 0 0 18 18 17 0 Stage III sporulation protein D GLE1 PF07817.13 ORX86645.1 - 4e-09 36.1 53.8 12 5.0 0.1 17.4 1 1 18 19 19 19 0 GLE1-like protein CENP-F_leu_zip PF10473.9 ORX86645.1 - 3e-08 33.8 61.4 25 4.9 0.0 20.2 21 1 0 21 21 21 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.11 ORX86645.1 - 3e-08 33.9 110.1 0.31 11.1 0.5 18.1 2 1 18 20 20 20 14 Apolipophorin-III precursor (apoLp-III) DUF1843 PF08898.10 ORX86645.1 - 3.7e-08 33.8 24.2 30 5.2 0.0 16.0 18 0 0 18 18 18 0 Domain of unknown function (DUF1843) VBS PF08913.10 ORX86645.1 - 0.00014 22.3 92.5 5 7.6 0.5 19.0 18 1 1 19 19 19 1 Vinculin Binding Site Abhydrolase_8 PF06259.12 ORX86645.1 - 0.00023 20.9 125.7 0.63 9.6 0.6 19.1 16 3 3 19 19 19 9 Alpha/beta hydrolase Baculo_PEP_C PF04513.12 ORX86645.1 - 0.00073 19.6 167.2 0.015 15.4 2.4 20.8 4 2 11 20 20 19 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.15 ORX86645.1 - 0.0074 16.2 32.8 80 3.1 0.0 15.1 18 0 0 18 18 18 0 Protein of unknown function (DUF1759) DUF5344 PF17279.2 ORX86645.1 - 0.01 16.4 61.0 40 4.9 0.1 16.3 19 0 0 19 19 16 0 Family of unknown function (DUF5344) GhoS PF11080.8 ORX86645.1 - 0.039 13.9 55.7 1.7 8.7 0.0 16.6 17 2 1 18 18 18 0 Endoribonuclease GhoS FlaC_arch PF05377.11 ORX86645.1 - 3 8.3 71.6 39 4.7 0.1 19.1 21 0 0 21 21 18 0 Flagella accessory protein C (FlaC) Chitin_synth_2 PF03142.15 ORX86704.1 - 1.5e-281 934.6 1.7 2.1e-281 934.1 1.7 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX86704.1 - 5e-16 59.3 0.1 1.5e-15 57.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX86704.1 - 4.9e-12 46.2 4.6 4.9e-12 46.2 4.6 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX86704.1 - 5.5e-06 26.0 0.1 0.0046 16.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX86704.1 - 0.0089 15.8 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1828 PF08861.10 ORX86704.1 - 0.19 12.0 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF4229 PF14012.6 ORX86704.1 - 7.7 6.7 14.5 10 6.3 8.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) CBFD_NFYB_HMF PF00808.23 ORX86706.1 - 3.1e-28 97.8 0.6 4.5e-28 97.3 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX86706.1 - 4.4e-06 27.1 0.1 6.4e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORX86706.1 - 0.0029 17.7 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 ORX86706.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.16 ORX86706.1 - 0.035 14.1 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-X PF09415.10 ORX86706.1 - 0.044 14.1 0.1 0.08 13.3 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Metallophos PF00149.28 ORX86707.1 - 2.1e-37 129.6 0.7 3.5e-37 128.9 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX86707.1 - 0.0019 18.6 0.2 0.0041 17.5 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORX86707.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Lyase_1 PF00206.20 ORX86708.1 - 6.6e-121 403.5 0.0 8.4e-121 403.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ORX86708.1 - 1.4e-26 92.6 0.1 3.1e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Rsbr_N PF08678.10 ORX86708.1 - 0.076 13.1 0.2 7.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Rsbr N terminal Aldo_ket_red PF00248.21 ORX86709.1 - 1.9e-77 260.4 0.0 2.2e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNARE_assoc PF09335.11 ORX86710.1 - 3.5e-20 72.7 6.1 3.5e-20 72.7 6.1 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1673 PF07895.11 ORX86710.1 - 0.97 9.1 11.3 0.82 9.3 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Ribosomal_L27A PF00828.19 ORX86711.1 - 9.3e-38 129.8 3.6 1.2e-37 129.4 3.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NNMT_PNMT_TEMT PF01234.17 ORX86711.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family C2 PF00168.30 ORX86712.1 - 4.5e-22 78.3 0.0 1.6e-21 76.5 0.0 1.7 2 0 0 2 2 2 1 C2 domain DUF3704 PF12488.8 ORX86713.1 - 0.22 11.2 6.8 6.7 6.5 0.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) AAA PF00004.29 ORX86714.1 - 2e-55 186.8 0.0 8.3e-40 136.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX86714.1 - 4.7e-11 42.3 0.1 2.4e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 ORX86714.1 - 4.8e-10 39.8 0.4 0.00035 20.9 0.0 3.7 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.12 ORX86714.1 - 4.6e-09 36.2 0.0 0.0019 18.0 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORX86714.1 - 5e-09 36.8 0.1 0.0022 18.4 0.0 3.0 3 1 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 ORX86714.1 - 1.9e-08 34.0 2.0 1.7e-07 30.9 0.2 3.1 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 ORX86714.1 - 3.8e-08 32.9 0.1 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 ORX86714.1 - 4.4e-08 33.4 0.0 2.3e-05 24.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORX86714.1 - 5.3e-08 33.0 0.0 0.0022 18.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORX86714.1 - 2.9e-07 30.1 0.2 0.0075 15.7 0.1 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORX86714.1 - 4.9e-07 29.7 0.1 0.015 15.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORX86714.1 - 6.2e-07 30.0 0.0 0.012 16.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORX86714.1 - 3.1e-06 27.5 0.0 0.039 14.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 ORX86714.1 - 3.7e-06 27.2 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ORX86714.1 - 1.4e-05 25.1 0.0 0.093 12.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORX86714.1 - 1.9e-05 24.5 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 ORX86714.1 - 2.9e-05 24.0 2.4 0.042 13.8 0.0 3.3 4 0 0 4 4 3 2 NACHT domain Sigma54_activat PF00158.26 ORX86714.1 - 0.0001 22.0 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORX86714.1 - 0.00011 21.8 0.1 0.04 13.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 ORX86714.1 - 0.00012 22.1 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORX86714.1 - 0.00014 21.5 1.7 1.1 8.8 0.0 3.7 3 1 0 4 4 4 2 AAA domain ATPase PF06745.13 ORX86714.1 - 0.00016 21.1 2.7 0.0058 16.0 0.1 2.8 3 0 0 3 3 3 1 KaiC ABC_tran PF00005.27 ORX86714.1 - 0.00017 22.1 0.5 0.12 12.9 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 ORX86714.1 - 0.00027 20.8 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 ORX86714.1 - 0.0006 19.1 0.2 0.42 9.8 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.16 ORX86714.1 - 0.00061 19.3 0.0 0.84 9.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ATPase_2 PF01637.18 ORX86714.1 - 0.0008 19.4 3.4 11 5.9 0.0 4.3 3 2 1 5 5 4 0 ATPase domain predominantly from Archaea CDC48_N PF02359.18 ORX86714.1 - 0.00083 19.5 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.11 ORX86714.1 - 0.00086 19.2 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORX86714.1 - 0.00097 19.4 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORX86714.1 - 0.0012 18.6 0.0 0.76 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 ORX86714.1 - 0.0014 17.8 0.0 0.83 8.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 ORX86714.1 - 0.0029 17.9 0.2 1.3 9.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.9 ORX86714.1 - 0.0049 16.1 0.1 1.4 8.0 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 ORX86714.1 - 0.0056 17.1 0.2 2.3 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORX86714.1 - 0.016 15.2 0.0 2.9 7.9 0.1 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 ORX86714.1 - 0.026 13.8 0.1 0.79 9.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 ORX86714.1 - 0.033 13.6 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DAP3 PF10236.9 ORX86714.1 - 0.035 13.3 0.1 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 ORX86714.1 - 0.076 12.1 0.0 6.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 ORX86714.1 - 0.082 13.2 0.4 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_29 PF13555.6 ORX86714.1 - 0.11 12.3 0.2 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 ORX86714.1 - 0.11 12.6 0.2 38 4.4 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain CPT PF07931.12 ORX86714.1 - 0.14 12.0 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein LRR_4 PF12799.7 ORX86715.1 - 1.9e-09 37.6 3.5 0.0003 21.1 0.2 3.7 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX86715.1 - 3.7e-06 26.6 0.1 5.3e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORX86715.1 - 8.4e-05 22.3 3.8 0.0015 18.3 0.2 2.9 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 ORX86715.1 - 0.074 13.2 0.2 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 ORX86715.1 - 0.81 10.5 5.5 7.7 7.5 0.2 3.5 3 1 0 3 3 3 0 Leucine Rich Repeat PH PF00169.29 ORX86716.1 - 4.9e-08 33.4 0.4 7.4e-08 32.8 0.4 1.3 1 0 0 1 1 1 1 PH domain PBD PF00786.28 ORX86716.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH_2 PF08458.10 ORX86716.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Glyco_hydro_18 PF00704.28 ORX86717.1 - 6.8e-23 81.9 0.3 6.8e-23 81.9 0.3 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_2 PF00553.19 ORX86717.1 - 3.7e-07 30.4 0.8 1.1e-06 28.9 0.2 2.2 2 0 0 2 2 2 1 Cellulose binding domain CBM_19 PF03427.13 ORX86717.1 - 0.0034 17.3 2.1 0.013 15.4 2.1 2.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) Plasmodium_HRP PF05403.11 ORX86717.1 - 0.5 10.1 169.0 0.25 11.1 69.1 2.7 1 1 2 3 3 3 0 Plasmodium histidine-rich protein (HRPII/III) PPR_2 PF13041.6 ORX86718.1 - 3.3e-08 33.6 0.2 5.4e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 ORX86718.1 - 0.0001 22.3 0.2 0.0011 19.0 0.2 2.3 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX86718.1 - 0.005 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORX86718.1 - 0.0054 16.9 0.0 2.1 8.8 0.0 3.2 3 0 0 3 3 3 1 PPR repeat Methyltransf_32 PF13679.6 ORX86718.1 - 0.082 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 ORX86719.1 - 1.8e-25 90.3 1.6 7.6e-25 88.3 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX86719.1 - 2.3e-16 59.3 67.2 0.00032 21.1 10.7 6.8 5 0 0 5 5 5 5 Carbohydrate binding domain DUF3573 PF12097.8 ORX86719.1 - 0.87 8.3 3.8 4.4 6.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3573) CBM_5_12 PF02839.14 ORX86720.1 - 4.5e-09 36.4 24.0 6.9e-05 23.2 5.5 3.1 2 0 0 2 2 2 2 Carbohydrate binding domain LPMO_10 PF03067.15 ORX86720.1 - 0.0038 17.9 2.6 0.0062 17.2 0.0 2.6 2 2 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_5_12_2 PF14600.6 ORX86720.1 - 0.0039 17.1 13.9 0.072 13.0 5.0 2.5 2 0 0 2 2 2 2 Cellulose-binding domain Glyco_hydro_61 PF03443.14 ORX86720.1 - 0.013 15.4 1.9 0.48 10.3 0.1 3.0 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 Homeodomain PF00046.29 ORX86785.1 - 1.4e-18 66.5 4.2 1.9e-18 66.1 4.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX86785.1 - 0.0023 17.8 0.1 0.0041 17.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain ColG_sub PF18496.1 ORX86786.1 - 0.36 11.0 3.6 14 5.9 0.0 3.1 2 1 1 3 3 3 0 Collagenase G catalytic helper subdomain Aminotran_4 PF01063.19 ORX86787.1 - 1e-28 100.7 0.0 1.3e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Tyrosinase PF00264.20 ORX86788.1 - 1.2e-36 127.1 11.0 5.5e-36 124.9 9.5 2.4 2 1 0 2 2 2 1 Common central domain of tyrosinase TPT PF03151.16 ORX86790.1 - 1.8e-27 96.5 25.9 2.1e-27 96.2 25.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORX86790.1 - 9.7e-08 32.3 36.4 0.00025 21.2 12.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family Bromodomain PF00439.25 ORX86792.1 - 2.4e-22 78.8 0.5 4.8e-22 77.8 0.5 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 ORX86792.1 - 3.3e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX86792.1 - 2.7e-06 27.3 0.0 5.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX86792.1 - 0.0001 22.6 0.1 0.00021 21.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX86792.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_9 PF00759.19 ORX86793.1 - 6e-115 385.0 0.2 6.9e-115 384.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_76 PF03663.14 ORX86793.1 - 0.0046 16.5 2.4 1.4 8.4 0.0 2.7 1 1 2 3 3 3 2 Glycosyl hydrolase family 76 Cyclin PF08613.11 ORX86794.1 - 3.8e-13 50.1 0.4 4.4e-13 49.9 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX86794.1 - 1.6e-06 27.8 0.1 2.3e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain StbA PF06406.11 ORX86794.1 - 0.088 12.0 0.2 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 StbA protein zf-C2H2 PF00096.26 ORX86795.1 - 6.8e-13 48.3 7.5 2.2e-06 27.8 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX86795.1 - 2.4e-08 34.1 9.9 1.1e-06 28.8 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX86795.1 - 2.7e-08 34.0 6.7 0.00039 21.0 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX86795.1 - 6.4e-07 29.6 3.9 2.8e-05 24.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX86795.1 - 9.2e-05 22.6 1.9 0.0052 17.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX86795.1 - 0.014 15.4 3.2 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 ORX86795.1 - 0.02 14.8 2.0 0.048 13.6 0.5 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 ORX86795.1 - 0.24 11.2 7.5 2 8.3 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain CAP_GLY PF01302.25 ORX86796.1 - 1.4e-11 44.2 0.4 2.6e-11 43.4 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 ORX86796.1 - 7.4e-08 32.1 13.8 2.1e-05 24.3 7.7 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 ORX86796.1 - 0.0035 16.3 23.1 0.0035 16.3 23.1 6.3 1 1 7 8 8 8 3 Spc7 kinetochore protein DUF1192 PF06698.11 ORX86796.1 - 0.022 14.8 0.9 0.022 14.8 0.9 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF1192) Filament PF00038.21 ORX86796.1 - 0.14 11.7 99.9 0.1 12.2 12.8 5.8 2 1 2 4 4 4 0 Intermediate filament protein CCDC23 PF15674.5 ORX86796.1 - 2.2 8.3 8.5 2.5 8.2 1.3 3.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 Ras PF00071.22 ORX86797.1 - 8.8e-55 184.7 0.0 1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX86797.1 - 7.4e-23 81.0 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX86797.1 - 1.2e-08 34.6 0.0 1.4e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX86797.1 - 0.0028 17.2 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX86797.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase RabGAP-TBC PF00566.18 ORX86798.1 - 2.9e-51 174.2 0.1 3.6e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1640 PF07798.11 ORX86799.1 - 1.3e-45 155.6 9.8 1.4e-45 155.5 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 ORX86799.1 - 0.0021 18.2 0.9 0.033 14.4 0.9 2.4 1 1 0 1 1 1 1 Homeobox associated leucine zipper FlaC_arch PF05377.11 ORX86799.1 - 0.012 16.0 4.8 1.7 9.1 1.2 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 ORX86799.1 - 0.12 12.9 4.0 0.3 11.5 1.5 2.3 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Uso1_p115_C PF04871.13 ORX86799.1 - 0.58 10.5 6.9 0.75 10.2 3.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.12 ORX86799.1 - 0.74 9.9 4.4 11 6.0 0.7 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 ORX86799.1 - 0.77 10.1 9.2 34 4.8 9.4 2.0 1 1 0 1 1 1 0 YlqD protein TPR_MLP1_2 PF07926.12 ORX86799.1 - 0.9 9.6 9.0 1.6 8.8 4.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 ORX86799.1 - 1.3 8.8 7.6 2.5 7.9 4.4 2.7 2 1 0 2 2 2 0 Septum formation initiator YabA PF06156.13 ORX86799.1 - 1.9 9.2 8.6 4.9 7.9 5.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 ORX86799.1 - 8.9 6.5 9.4 20 5.4 0.1 3.1 3 1 0 3 3 3 0 Basic region leucine zipper Cytochrom_C1 PF02167.15 ORX86800.1 - 2e-98 328.5 0.0 2.5e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORX86800.1 - 0.0016 18.8 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORX86800.1 - 0.01 16.9 0.0 0.035 15.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c Arrestin_C PF02752.22 ORX86859.1 - 2.6e-11 44.1 2.7 3.7e-08 33.9 0.8 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX86859.1 - 7.2e-09 35.9 0.2 7.3e-07 29.3 0.0 2.9 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX86859.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 ORX86859.1 - 0.025 13.7 0.3 1.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Rgp1 Sulfatase PF00884.23 ORX86860.1 - 2.9e-25 89.3 1.3 5.1e-25 88.5 1.3 1.3 1 0 0 1 1 1 1 Sulfatase DUF4083 PF13314.6 ORX86860.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) CBM_21 PF03370.13 ORX86862.1 - 2.9e-28 98.3 0.2 4.4e-28 97.7 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORX86862.1 - 1.1e-08 35.5 0.4 2.1e-08 34.6 0.4 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM9_1 PF06452.11 ORX86863.1 - 0.00012 22.0 1.8 0.00044 20.2 0.1 2.4 2 1 0 2 2 2 1 Carbohydrate family 9 binding domain-like Pilin_GH PF16734.5 ORX86863.1 - 0.097 13.0 0.1 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative RhoGEF PF00621.20 ORX86864.1 - 0.0014 18.9 0.0 0.0056 17.0 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain AFT PF08731.11 ORX86864.1 - 0.097 13.1 0.2 0.27 11.6 0.2 1.7 1 0 0 1 1 1 0 Transcription factor AFT Serpin PF00079.20 ORX86865.1 - 8e-69 232.7 0.2 8.9e-69 232.6 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF5643 PF18705.1 ORX86865.1 - 0.0062 16.5 0.8 0.014 15.4 0.1 1.9 2 1 1 3 3 3 1 Family of unknown function (DUF5643) PAW PF04721.17 ORX86865.1 - 0.016 15.0 0.2 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW FMO-like PF00743.19 ORX86866.1 - 3.2e-93 312.9 0.0 4.1e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORX86866.1 - 6.4e-14 51.9 0.0 4.4e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX86866.1 - 1.9e-11 43.8 2.7 4.3e-09 36.1 0.2 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX86866.1 - 1.2e-07 31.3 0.2 4.8e-05 22.7 0.0 3.4 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORX86866.1 - 3.1e-05 24.0 0.2 0.15 12.0 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORX86866.1 - 0.0002 21.9 1.5 0.0011 19.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX86866.1 - 0.0043 16.7 0.5 18 4.8 0.0 3.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ORX86866.1 - 0.019 15.1 0.2 0.66 10.0 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 ORX86866.1 - 0.019 15.2 0.3 0.68 10.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 ORX86866.1 - 0.15 12.5 0.1 6.6 7.2 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Eclosion PF04736.12 ORX86866.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone FAD_binding_2 PF00890.24 ORX86866.1 - 0.25 10.4 1.3 12 4.8 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 ORX86866.1 - 0.46 9.7 1.5 3.9 6.7 0.7 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORX86866.1 - 1 8.6 1.8 4.1 6.5 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FSH1 PF03959.13 ORX86867.1 - 3.5e-39 134.7 0.0 5.6e-39 134.0 0.0 1.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORX86867.1 - 0.033 14.8 0.0 0.055 14.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ORX86867.1 - 0.11 12.6 0.2 0.91 9.6 0.2 2.0 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 ORX86868.1 - 2.4e-08 34.9 0.1 9.2e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 ORX86868.1 - 1.8e-05 23.8 0.0 2.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 ORX86868.1 - 6e-05 22.8 0.0 0.00025 20.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX86868.1 - 6.4e-05 22.5 0.1 0.0011 18.5 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORX86868.1 - 0.00044 19.9 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORX86868.1 - 0.0023 16.7 0.1 0.0078 14.9 0.0 1.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 ORX86868.1 - 0.0031 16.8 0.0 0.0068 15.7 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORX86868.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 ORX86868.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 ORX86869.1 - 2.7e-84 283.6 0.0 3.2e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5404 PF17397.2 ORX86869.1 - 0.038 14.1 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5404) RTTN_N PF14726.6 ORX86869.1 - 0.14 12.9 0.1 0.4 11.5 0.1 1.7 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning Transferase PF02458.15 ORX86870.1 - 1.6e-13 50.1 0.0 1.4e-12 47.0 0.0 2.3 1 1 0 1 1 1 1 Transferase family DNA_topoisoIV PF00521.20 ORX86870.1 - 0.19 10.5 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A ketoacyl-synt PF00109.26 ORX86871.1 - 2.9e-81 272.8 0.0 6.1e-81 271.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ORX86871.1 - 3.6e-58 197.1 0.0 6e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ORX86871.1 - 3.9e-55 187.6 0.6 6e-55 187.0 0.6 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ORX86871.1 - 3.4e-41 140.0 0.0 1.1e-40 138.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ORX86871.1 - 1.7e-19 70.4 0.0 7.1e-19 68.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORX86871.1 - 2.2e-16 60.3 0.0 5.5e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 ORX86871.1 - 1.5e-12 47.7 0.0 3.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX86871.1 - 2.4e-11 44.2 0.0 1.9e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX86871.1 - 2.6e-09 37.6 0.0 6.7e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX86871.1 - 2.7e-08 33.7 0.0 9.6e-08 32.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 ORX86871.1 - 2.4e-05 23.8 0.0 5.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 ORX86871.1 - 0.00026 20.8 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 ORX86871.1 - 0.0012 18.7 0.0 0.0067 16.2 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase Ubie_methyltran PF01209.18 ORX86871.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family SAT PF16073.5 ORX86871.1 - 0.002 17.9 0.4 0.005 16.6 0.4 1.7 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_33 PF10017.9 ORX86871.1 - 0.02 14.1 0.0 0.074 12.2 0.0 1.8 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent KR PF08659.10 ORX86872.1 - 1.2e-57 194.8 0.8 1.4e-57 194.5 0.0 1.6 2 0 0 2 2 2 1 KR domain ADH_zinc_N_2 PF13602.6 ORX86872.1 - 7.9e-18 65.8 0.0 2.7e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX86872.1 - 6.2e-16 58.6 0.1 1.7e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORX86872.1 - 3e-12 46.4 0.7 1.5e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX86872.1 - 3.3e-07 30.1 0.4 6.8e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ORX86872.1 - 4.6e-05 23.7 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Rsm22 PF09243.10 ORX86872.1 - 0.091 12.0 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.25 ORX86935.1 - 6.3e-73 245.4 0.0 7.9e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX86935.1 - 7.9e-35 120.4 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORX86935.1 - 1.1e-10 42.0 3.4 2.6e-10 40.8 3.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 ORX86935.1 - 3.2e-06 27.4 0.0 1.1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 ORX86935.1 - 2.8e-05 23.2 0.0 4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX86935.1 - 9.1e-05 21.9 0.0 0.00021 20.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORX86935.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX86935.1 - 0.029 14.0 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORX86935.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ubiquitin PF00240.23 ORX86936.1 - 3.3e-23 81.2 0.2 4.8e-23 80.7 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 ORX86936.1 - 8.5e-12 45.0 3.5 8.5e-12 45.0 3.5 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 ORX86936.1 - 1.3e-10 40.9 0.6 2.1e-10 40.3 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Transp_Tc5_C PF04236.15 ORX86936.1 - 0.013 15.8 3.5 0.021 15.2 2.3 1.9 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ras PF00071.22 ORX86937.1 - 4.8e-51 172.6 0.1 5.7e-51 172.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX86937.1 - 2.6e-32 111.5 0.0 4e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX86937.1 - 2.2e-13 50.1 0.0 2.6e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX86937.1 - 6.4e-07 29.1 0.1 1.1e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX86937.1 - 6.8e-06 26.1 0.0 9.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX86937.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX86937.1 - 0.0028 17.6 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 ORX86937.1 - 0.036 13.2 0.2 1.9 7.5 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 ORX86937.1 - 0.04 14.3 0.0 0.066 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 ORX86937.1 - 0.044 13.2 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORX86937.1 - 0.051 13.8 0.0 0.58 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORX86937.1 - 0.14 11.9 0.0 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 ORX86937.1 - 0.2 11.2 0.0 5.6 6.5 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B SMI1_KNR4 PF09346.10 ORX86942.1 - 4.9e-05 23.7 0.1 9.5e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORX86942.1 - 0.00025 21.4 0.0 0.00056 20.3 0.0 1.8 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 ORX86942.1 - 0.038 13.7 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Syntaxin_2 PF14523.6 ORX86943.1 - 2.9e-28 98.2 11.5 1.6e-24 86.1 4.3 2.8 3 0 0 3 3 3 2 Syntaxin-like protein SNARE PF05739.19 ORX86943.1 - 4e-15 55.5 1.8 8.9e-15 54.4 0.4 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 ORX86943.1 - 4e-09 36.4 13.7 1.1e-08 35.0 13.7 1.7 1 1 0 1 1 1 1 Syntaxin DUF2207 PF09972.9 ORX86943.1 - 0.0025 16.6 2.7 0.013 14.3 0.0 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF812 PF05667.11 ORX86943.1 - 0.0074 15.2 16.5 0.2 10.5 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF812) MCPsignal PF00015.21 ORX86943.1 - 0.0082 16.0 8.3 0.035 13.9 0.5 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain MPS2 PF17060.5 ORX86943.1 - 0.017 14.4 12.7 0.022 14.1 1.7 2.3 1 1 1 2 2 2 0 Monopolar spindle protein 2 Mobilization_B PF17511.2 ORX86943.1 - 0.029 14.7 2.4 0.21 11.9 0.0 2.6 2 1 1 3 3 3 0 Mobilization protein B Trimer_CC PF08954.11 ORX86943.1 - 0.032 13.8 0.5 0.11 12.1 0.5 1.9 1 0 0 1 1 1 0 Trimerisation motif Allexi_40kDa PF05549.11 ORX86943.1 - 0.3 10.5 5.9 0.3 10.6 1.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF883 PF05957.13 ORX86943.1 - 0.35 11.5 8.1 18 6.0 0.6 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) T2SSF PF00482.23 ORX86943.1 - 0.37 10.7 2.8 0.98 9.4 0.2 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF5082 PF16888.5 ORX86943.1 - 1.2 9.4 11.6 0.23 11.8 1.3 3.3 2 2 0 3 3 3 0 Domain of unknown function (DUF5082) XhlA PF10779.9 ORX86943.1 - 1.2 9.4 4.8 2.3 8.5 0.3 3.3 3 0 0 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 ORX86943.1 - 1.6 8.8 12.1 0.32 11.0 1.3 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) V-SNARE PF05008.15 ORX86943.1 - 2.1 8.8 13.4 1.1 9.7 0.8 3.7 2 2 3 5 5 5 0 Vesicle transport v-SNARE protein N-terminus Synaptobrevin PF00957.21 ORX86943.1 - 3.2 7.6 9.7 0.22 11.3 0.9 3.1 3 1 0 3 3 3 0 Synaptobrevin ING PF12998.7 ORX86943.1 - 6.3 7.5 10.9 1.2 9.8 1.0 2.7 3 1 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding SlyX PF04102.12 ORX86943.1 - 7.6 7.2 13.2 0.27 11.9 0.8 3.8 3 2 0 3 3 3 0 SlyX FAM76 PF16046.5 ORX86943.1 - 8.2 5.7 8.9 3.6 6.9 6.4 1.6 1 1 1 2 2 2 0 FAM76 protein DUF16 PF01519.16 ORX86943.1 - 9.2 6.8 13.0 0.34 11.4 2.6 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 DPBB_1 PF03330.18 ORX86944.1 - 4.5e-08 33.3 0.0 5e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX86944.1 - 0.00026 20.8 0.1 0.0003 20.6 0.1 1.1 1 0 0 1 1 1 1 Barwin family SAM_decarbox PF01536.16 ORX87010.1 - 1.6e-121 405.7 0.2 2.4e-113 378.8 0.1 3.0 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase Pyr_redox_2 PF07992.14 ORX87012.1 - 1.5e-51 175.4 0.0 1.7e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX87012.1 - 1e-17 64.4 0.1 2.8e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX87012.1 - 6.4e-17 61.9 0.0 8.1e-15 55.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX87012.1 - 4.7e-05 22.8 0.1 0.0005 19.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ORX87012.1 - 0.0031 16.9 0.1 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX87012.1 - 0.0035 17.6 0.1 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX87012.1 - 0.0059 15.7 1.0 0.059 12.4 0.1 2.8 4 0 0 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 ORX87012.1 - 0.0066 15.6 0.1 0.23 10.5 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 ORX87012.1 - 0.0085 15.2 1.8 0.089 11.9 0.3 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORX87012.1 - 0.036 12.8 1.1 0.092 11.4 0.1 2.1 2 1 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 ORX87012.1 - 0.038 14.4 0.0 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 ORX87012.1 - 0.039 13.5 0.2 13 5.2 0.0 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase PolyA_pol PF01743.20 ORX87012.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Poly A polymerase head domain WD40 PF00400.32 ORX87013.1 - 3.4e-07 30.9 2.2 9.4e-07 29.5 0.8 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.10 ORX87013.1 - 0.00097 17.4 0.1 0.39 8.8 0.0 2.7 2 1 0 2 2 2 2 CRT10 ANAPC4_WD40 PF12894.7 ORX87013.1 - 0.034 14.5 0.1 0.25 11.7 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PALP PF00291.25 ORX87014.1 - 2.1e-56 191.5 0.0 2.5e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORX87014.1 - 8.1e-14 51.8 0.0 1.6e-05 25.3 0.0 3.0 2 0 0 2 2 2 2 CBS domain DUF4881 PF16222.5 ORX87014.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) AA_permease_2 PF13520.6 ORX87016.1 - 8.6e-54 183.0 47.4 1.1e-53 182.7 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX87016.1 - 1.4e-43 149.2 42.7 1.9e-43 148.7 42.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX87016.1 - 1.4e-09 37.8 4.5 1.4e-09 37.8 4.5 2.9 3 0 0 3 3 3 1 C-terminus of AA_permease AA_permease_2 PF13520.6 ORX87017.1 - 1.4e-61 208.6 47.5 1.8e-61 208.3 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX87017.1 - 2e-44 152.0 41.1 2.6e-44 151.6 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX87017.1 - 6.4e-11 42.2 9.2 1.8e-10 40.7 5.0 3.3 2 0 0 2 2 2 1 C-terminus of AA_permease CPP1-like PF11833.8 ORX87017.1 - 2.3 7.9 4.9 4.2 7.0 0.6 3.0 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AA_permease_2 PF13520.6 ORX87019.1 - 7.5e-54 183.2 46.6 9.5e-54 182.8 46.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX87019.1 - 8e-44 150.0 41.4 1.2e-43 149.4 41.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORX87019.1 - 4.5e-09 36.2 4.6 4.5e-09 36.2 4.6 3.1 4 0 0 4 4 4 1 C-terminus of AA_permease RNB PF00773.19 ORX87083.1 - 4.8e-83 279.2 3.1 9.7e-83 278.2 0.7 2.4 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 ORX87083.1 - 5.7e-19 67.9 0.0 1.2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 ORX87083.1 - 3.1e-12 46.4 0.0 8.6e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 ORX87083.1 - 2.2e-09 37.2 0.0 7.9e-09 35.4 0.0 2.0 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 ORX87083.1 - 3e-08 33.7 0.3 9.5e-06 25.7 0.1 3.1 3 0 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 ORX87083.1 - 0.024 15.0 0.0 0.076 13.4 0.0 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal HBS1_N PF08938.10 ORX87084.1 - 8.7e-12 45.2 0.1 3.2e-11 43.4 0.1 2.0 2 0 0 2 2 2 1 HBS1 N-terminus DNA_topoisoIV PF00521.20 ORX87085.1 - 1.9e-102 343.3 0.0 3.3e-102 342.6 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORX87085.1 - 9.2e-31 106.8 2.2 2.3e-30 105.5 0.0 2.9 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORX87085.1 - 1.4e-22 80.0 0.1 3.1e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 ORX87085.1 - 2.7e-05 24.6 0.0 0.00016 22.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORX87085.1 - 0.001 19.2 0.0 0.0035 17.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain IF-2B PF01008.17 ORX87086.1 - 6e-86 288.2 0.1 9.6e-86 287.5 0.1 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0492 PF15744.5 ORX87086.1 - 0.66 9.1 6.5 0.89 8.7 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Peptidase_S30 PF01577.16 ORX87086.1 - 3.9 7.0 8.1 6 6.4 8.1 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease ABC_membrane PF00664.23 ORX87087.1 - 2.3e-45 155.4 10.8 3e-45 155.0 10.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORX87087.1 - 9e-38 129.9 0.0 2.5e-37 128.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 ORX87087.1 - 1.4e-08 34.5 0.2 1.2e-05 24.9 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORX87087.1 - 0.00037 20.8 0.0 0.0031 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX87087.1 - 0.00042 20.7 0.0 0.00097 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORX87087.1 - 0.0026 17.6 0.2 0.013 15.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORX87087.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ORX87087.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 ORX87087.1 - 0.0058 17.1 0.0 0.088 13.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORX87087.1 - 0.0068 16.1 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 ORX87087.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 ORX87087.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 ORX87087.1 - 0.025 15.1 0.1 0.058 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 ORX87087.1 - 0.035 14.7 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX87087.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORX87087.1 - 0.044 14.0 0.0 0.18 12.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX87087.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX87087.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 ORX87087.1 - 0.083 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORX87087.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF973 PF06157.11 ORX87087.1 - 0.43 9.6 8.6 2 7.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DEAD PF00270.29 ORX87088.1 - 4.5e-37 127.5 0.2 1.6e-36 125.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX87088.1 - 3.1e-25 88.7 0.1 3e-24 85.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ORX87088.1 - 7.5e-07 28.6 0.0 7.5e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ORX87088.1 - 2.5e-06 27.6 0.1 5.1e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORX87088.1 - 0.1 12.3 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain CAP_N PF01213.19 ORX87089.1 - 0.017 14.6 1.0 0.017 14.6 1.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal End3 PF12761.7 ORX87089.1 - 0.035 14.3 0.8 0.035 14.3 0.8 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF2076 PF09849.9 ORX87089.1 - 0.041 13.9 0.7 0.64 10.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) AKNA PF12443.8 ORX87089.1 - 0.26 12.0 6.1 0.38 11.4 0.0 3.2 3 1 0 3 3 3 0 AT-hook-containing transcription factor Macoilin PF09726.9 ORX87089.1 - 0.33 9.4 2.6 0.46 9.0 2.6 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 ORX87089.1 - 0.39 10.6 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Ada_Zn_binding PF02805.16 ORX87090.1 - 0.0021 18.0 1.9 0.0021 18.0 1.9 1.6 1 1 0 1 1 1 1 Metal binding domain of Ada CNH PF00780.22 ORX87091.1 - 1.4e-74 251.2 0.0 2.3e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORX87091.1 - 1.8e-36 126.1 0.0 8.3e-36 123.9 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 ORX87091.1 - 1.5e-32 112.5 0.1 4.2e-32 111.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORX87091.1 - 1.1e-13 51.0 0.0 2.5e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.6 ORX87091.1 - 0.0024 18.1 0.0 0.047 14.0 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORX87091.1 - 0.004 17.6 0.1 0.026 15.0 0.0 2.4 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 ORX87091.1 - 0.023 14.7 0.1 0.11 12.4 0.1 2.1 1 1 0 1 1 1 0 PH domain PH_13 PF16652.5 ORX87091.1 - 0.08 12.8 2.8 1.3 8.8 2.8 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 ORX87091.1 - 0.18 11.7 0.5 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 PH domain DSBA PF01323.20 ORX87092.1 - 2.9e-22 79.4 0.0 3.3e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SinI PF08671.10 ORX87092.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 Anti-repressor SinI Sec63 PF02889.16 ORX87093.1 - 3.8e-152 504.7 0.1 2.2e-81 272.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORX87093.1 - 1.8e-52 177.6 0.1 2.9e-27 95.5 0.2 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 ORX87093.1 - 5.3e-25 88.4 0.0 1.4e-12 48.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX87093.1 - 5.2e-17 62.2 0.0 6.7e-08 32.9 0.0 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 ORX87093.1 - 9.2e-08 32.2 0.1 3.2e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_22 PF13401.6 ORX87093.1 - 1.7e-06 28.3 0.4 0.1 12.9 0.1 3.7 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ORX87093.1 - 0.1 12.3 0.3 4.3 7.0 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein ParA PF10609.9 ORX87093.1 - 0.23 10.9 0.5 4.6 6.6 0.5 2.3 1 1 1 2 2 2 0 NUBPL iron-transfer P-loop NTPase Tubulin PF00091.25 ORX87094.1 - 2.4e-70 236.8 0.0 4.4e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX87094.1 - 1.2e-41 141.8 0.1 1.9e-41 141.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX87094.1 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 ORX87094.1 - 0.00054 19.3 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Tubulin like Tubulin_3 PF14881.6 ORX87094.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Arrestin_C PF02752.22 ORX87095.1 - 3.2e-13 50.3 0.1 6.2e-11 42.9 0.1 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX87095.1 - 0.089 12.8 0.1 0.79 9.8 0.0 2.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain EF-hand_1 PF00036.32 ORX87096.1 - 6.2e-13 47.3 7.2 1.6e-05 24.1 0.6 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ORX87096.1 - 9.2e-11 40.8 8.3 0.00019 21.1 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 ORX87096.1 - 4.8e-10 39.8 8.8 0.00093 19.6 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair ZZ PF00569.17 ORX87096.1 - 7.2e-09 35.3 9.4 1.2e-08 34.7 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_5 PF13202.6 ORX87096.1 - 2.6e-07 29.8 9.0 0.0088 15.5 1.1 3.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 ORX87096.1 - 7e-06 25.8 14.7 0.0013 18.5 0.4 4.4 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 ORX87096.1 - 0.11 12.4 0.4 2 8.4 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.11 ORX87096.1 - 0.17 12.0 0.0 2.8 8.1 0.0 2.2 1 1 1 2 2 2 0 EF hand zf-ribbon_3 PF13248.6 ORX87096.1 - 0.18 11.3 2.7 0.48 9.9 2.7 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Caleosin PF05042.13 ORX87096.1 - 1.6 8.7 4.7 0.76 9.7 0.1 2.6 3 1 1 4 4 4 0 Caleosin related protein CHCH PF06747.13 ORX87097.1 - 0.00077 19.5 3.0 0.025 14.7 0.5 1.9 1 1 2 3 3 3 3 CHCH domain CX9C PF16860.5 ORX87097.1 - 0.013 15.5 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Yip1 PF04893.17 ORX87098.1 - 3.5e-12 46.4 9.5 3.5e-12 46.4 9.5 1.6 1 1 1 2 2 2 1 Yip1 domain Peptidase_M16 PF00675.20 ORX87166.1 - 3.2e-17 62.9 0.1 4.2e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) UDPG_MGDP_dh_N PF03721.14 ORX87167.1 - 1.3e-63 214.0 0.1 2.8e-63 212.9 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 ORX87167.1 - 1e-36 125.5 0.1 2.7e-35 121.0 0.1 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 ORX87167.1 - 9.9e-31 105.8 0.0 2.1e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 ORX87167.1 - 0.0002 21.8 0.0 1.2 9.8 0.0 3.4 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORX87167.1 - 0.00095 19.4 0.0 0.069 13.3 0.0 2.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ORX87167.1 - 0.0039 16.9 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA OTCace PF00185.24 ORX87167.1 - 0.014 15.5 0.1 0.48 10.5 0.1 2.3 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ldh_1_N PF00056.23 ORX87167.1 - 0.028 14.5 0.3 2.9 8.0 0.0 3.1 2 2 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORX87167.1 - 0.05 13.9 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ORX87167.1 - 0.053 12.8 0.2 0.11 11.8 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain eIF3g PF12353.8 ORX87168.1 - 1.1e-43 148.6 2.0 1.7e-43 147.9 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 ORX87168.1 - 3.9e-19 68.2 0.0 8.3e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX87168.1 - 0.00013 21.8 0.0 0.00033 20.4 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORX87168.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Chordopox_G2 PF05796.12 ORX87168.1 - 0.15 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus protein G2 zf-ANAPC11 PF12861.7 ORX87169.1 - 9.5e-39 131.4 14.8 1.2e-38 131.1 14.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORX87169.1 - 8.7e-22 77.2 15.1 1.1e-21 76.9 15.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORX87169.1 - 5.2e-05 23.5 20.7 0.0011 19.3 20.5 2.4 1 1 1 2 2 2 1 Ring finger domain zf-Nse PF11789.8 ORX87169.1 - 0.12 12.2 5.0 0.17 11.7 5.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 ORX87169.1 - 0.17 12.0 14.2 0.41 10.7 14.2 1.7 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORX87169.1 - 0.23 11.1 17.4 2.3 7.9 17.4 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 ORX87169.1 - 1.3 8.9 18.0 5.8 6.9 18.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORX87169.1 - 8.3 6.7 19.7 37 4.6 19.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Methyltransf_25 PF13649.6 ORX87170.1 - 3e-05 24.6 0.0 8.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX87170.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORX87170.1 - 0.00082 18.9 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ORX87170.1 - 0.0028 18.3 0.0 0.0066 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX87170.1 - 0.0045 16.5 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5_C PF17286.2 ORX87170.1 - 0.024 14.5 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain DREV PF05219.12 ORX87170.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 ORX87170.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 ORX87170.1 - 0.23 11.5 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain polyprenyl_synt PF00348.17 ORX87171.1 - 1.1e-61 208.2 0.0 1.6e-60 204.4 0.0 2.2 1 1 0 1 1 1 1 Polyprenyl synthetase Hydrolase_6 PF13344.6 ORX87172.1 - 5.8e-30 103.4 0.0 9.7e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX87172.1 - 5.6e-20 71.2 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORX87172.1 - 9.6e-11 42.4 0.0 2e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX87172.1 - 8.4e-07 29.2 0.3 0.00056 20.0 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase MitMem_reg PF13012.6 ORX87173.1 - 4.2e-32 110.9 0.1 6.5e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORX87173.1 - 4.2e-17 62.2 0.0 7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AAA PF00004.29 ORX87174.1 - 3.3e-40 137.6 0.0 5.5e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX87174.1 - 5.2e-22 77.4 2.0 2.4e-13 49.6 0.2 2.9 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 ORX87174.1 - 9.9e-07 29.3 0.2 0.00017 22.0 0.1 3.0 1 1 2 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 ORX87174.1 - 0.00027 20.9 0.0 0.00096 19.1 0.0 1.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 ORX87174.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_2 PF07724.14 ORX87174.1 - 0.00097 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 ORX87174.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORX87174.1 - 0.0024 17.8 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 ORX87174.1 - 0.0032 17.6 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX87174.1 - 0.0035 17.6 0.0 0.099 12.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ORX87174.1 - 0.0036 17.1 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORX87174.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 ORX87174.1 - 0.0073 16.8 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 ORX87174.1 - 0.0074 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.15 ORX87174.1 - 0.0076 15.1 0.2 0.012 14.5 0.2 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_5 PF07728.14 ORX87174.1 - 0.015 15.3 0.1 0.076 13.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ORX87174.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.13 ORX87174.1 - 0.043 13.0 0.1 0.084 12.1 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain SRPRB PF09439.10 ORX87174.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 ORX87174.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORX87174.1 - 0.087 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 ORX87174.1 - 0.095 13.2 0.1 0.27 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 ORX87174.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ORX87174.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Smac_DIABLO PF09057.10 ORX87174.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Guanylate_kin PF00625.21 ORX87174.1 - 0.12 12.1 0.0 6.4 6.4 0.0 2.3 1 1 1 2 2 2 0 Guanylate kinase KAP_NTPase PF07693.14 ORX87174.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 ORX87174.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CDC48_2 PF02933.17 ORX87175.1 - 0.042 13.6 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Ribosomal_L27A PF00828.19 ORX87176.1 - 8.9e-22 78.1 0.1 1.3e-21 77.6 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SANTA PF09133.10 ORX87177.1 - 5.8e-23 81.2 0.2 1.3e-22 80.1 0.2 1.6 1 0 0 1 1 1 1 SANTA (SANT Associated) Cornichon PF03311.14 ORX87178.1 - 4.4e-46 156.2 14.0 5e-46 156.0 14.0 1.0 1 0 0 1 1 1 1 Cornichon protein MARVEL PF01284.23 ORX87178.1 - 0.016 15.3 4.3 0.04 13.9 4.3 1.9 1 1 0 1 1 1 0 Membrane-associating domain IBR PF01485.21 ORX87179.1 - 1.2e-19 70.3 48.9 5.2e-11 42.6 8.0 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORX87179.1 - 0.0032 17.3 7.1 0.0032 17.3 7.1 4.5 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX87179.1 - 0.024 15.0 6.4 0.024 15.0 6.4 4.1 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 ORX87179.1 - 2.1 8.3 45.2 0.59 10.0 6.2 4.8 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S13_N PF08069.12 ORX87180.1 - 9.3e-31 105.7 0.1 1.8e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORX87180.1 - 3.3e-14 52.9 0.6 4.8e-14 52.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 ORX87180.1 - 0.073 13.0 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Ribosomal_S10 PF00338.22 ORX87181.1 - 4.9e-29 100.5 0.4 7.5e-29 99.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e COG7 PF10191.9 ORX87183.1 - 3.4e-103 346.4 12.7 4.7e-91 306.2 7.5 2.8 2 1 1 3 3 3 2 Golgi complex component 7 (COG7) DUF4254 PF14063.6 ORX87183.1 - 0.015 15.1 3.4 0.043 13.6 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) Formin_GBD_N PF18382.1 ORX87183.1 - 0.15 12.5 1.1 3.2 8.3 0.3 3.0 3 0 0 3 3 3 0 Formin N-terminal GTPase-binding domain UPF0184 PF03670.13 ORX87183.1 - 0.88 10.0 6.5 0.6 10.5 0.4 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) FAM178 PF14816.6 ORX87185.1 - 0.12 11.4 1.2 8.5 5.2 1.1 2.1 2 0 0 2 2 2 0 Family of unknown function, FAM178 DUF974 PF06159.13 ORX87186.1 - 1.1e-70 238.2 0.1 1.4e-70 237.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 ORX87186.1 - 4.6e-05 23.0 0.4 0.14 11.6 0.0 2.9 2 1 1 3 3 3 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 ORX87186.1 - 0.0019 18.3 0.0 0.58 10.3 0.0 2.8 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Ribosomal_L29 PF00831.23 ORX87187.1 - 2.2e-21 75.6 3.2 2.2e-21 75.6 3.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 ORX87187.1 - 0.14 12.6 9.9 0.073 13.5 2.3 2.1 1 1 1 2 2 2 0 Snapin/Pallidin MRP-L47 PF06984.13 ORX87187.1 - 0.29 11.3 4.2 0.24 11.6 1.5 2.2 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Prefoldin PF02996.17 ORX87187.1 - 1.1 9.2 10.0 4.1 7.4 2.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit Snf7 PF03357.21 ORX87187.1 - 3.2 7.3 12.0 2.6 7.6 1.0 2.1 1 1 1 2 2 2 0 Snf7 Ribosomal_S17_N PF16205.5 ORX87188.1 - 1.6e-33 114.9 0.5 3.4e-33 113.8 0.5 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORX87188.1 - 2.3e-27 94.9 0.4 3.7e-27 94.2 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 eIF2_C PF09173.11 ORX87189.1 - 2.1e-36 124.0 0.2 5.3e-36 122.7 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORX87189.1 - 4.1e-23 81.9 1.0 3.9e-22 78.7 1.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORX87189.1 - 7.7e-12 45.4 0.7 7.7e-12 45.4 0.7 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ORX87189.1 - 0.0012 18.8 0.3 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORX87189.1 - 0.0025 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORX87189.1 - 0.0037 17.3 0.1 0.0083 16.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 ORX87189.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Dynamin family PRMT5 PF05185.16 ORX87190.1 - 2.2e-68 229.5 0.0 3.5e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 ORX87190.1 - 8e-58 195.6 0.8 1.4e-57 194.9 0.8 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 ORX87190.1 - 9.3e-54 182.0 1.4 1.5e-53 181.3 1.4 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain USP8_dimer PF08969.11 ORX87190.1 - 0.055 13.7 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 USP8 dimerisation domain TarH PF02203.15 ORX87190.1 - 0.14 12.1 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue MFS_1 PF07690.16 ORX87191.1 - 3.8e-14 52.4 18.0 5.3e-14 51.9 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX87191.1 - 2.4e-12 46.9 10.0 2.4e-12 46.9 10.0 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORX87191.1 - 0.0022 17.1 4.8 0.0022 17.1 4.8 1.6 1 1 1 2 2 2 2 PUCC protein CPP1-like PF11833.8 ORX87191.1 - 0.027 14.1 2.9 0.064 12.9 2.7 1.8 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_1 PF07690.16 ORX87192.1 - 1.4e-12 47.3 24.3 1.4e-12 47.3 24.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORX87192.1 - 5e-11 42.6 6.0 1.5e-10 41.0 6.0 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Wzy_C_2 PF11846.8 ORX87192.1 - 0.098 12.6 0.3 0.27 11.1 0.3 1.7 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Sugar_tr PF00083.24 ORX87192.1 - 3.8 6.3 27.3 24 3.6 24.2 2.9 1 1 0 1 1 1 0 Sugar (and other) transporter PTR2 PF00854.21 ORX87259.1 - 2.7e-80 270.2 9.6 2.7e-80 270.2 9.6 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX87259.1 - 2.8e-12 46.3 35.1 2.6e-08 33.2 10.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Phage_holin_4_2 PF04020.13 ORX87259.1 - 1.9 9.2 11.7 2.1 9.1 0.6 3.5 3 0 0 3 3 3 0 Mycobacterial 4 TMS phage holin, superfamily IV Glyco_transf_34 PF05637.12 ORX87260.1 - 1.7e-24 86.9 4.2 1.2e-11 44.8 0.3 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORX87260.1 - 4.5e-05 23.1 0.3 0.00011 21.9 0.1 1.6 1 1 0 2 2 2 1 Protein of unknown function, DUF273 AA_permease PF00324.21 ORX87261.1 - 6.9e-126 420.6 47.9 8.3e-126 420.4 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX87261.1 - 3.4e-28 98.6 53.0 4.4e-28 98.3 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 ORX87261.1 - 0.025 14.3 0.7 0.057 13.1 0.7 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 Isochorismatase PF00857.20 ORX87262.1 - 2.9e-18 66.7 0.0 6e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Zip PF02535.22 ORX87263.1 - 7e-11 41.9 6.4 7.5e-11 41.8 6.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter LisH PF08513.11 ORX87266.1 - 1.2e-05 25.1 0.2 2.9e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 LisH ATP-synt_ab PF00006.25 ORX87267.1 - 2.1e-74 249.8 0.0 3.5e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORX87267.1 - 6.3e-50 168.7 0.2 1.1e-49 167.9 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORX87267.1 - 5.1e-20 71.8 1.9 1.5e-19 70.3 1.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ORX87267.1 - 0.047 13.8 1.7 0.32 11.2 0.3 2.5 1 1 1 2 2 2 0 HAS barrel domain ATPase_2 PF01637.18 ORX87267.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea WD40 PF00400.32 ORX87268.1 - 3.6e-08 33.9 6.2 0.16 12.9 0.2 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX87268.1 - 0.001 19.3 0.0 12 6.3 0.0 4.5 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1652 PF07865.11 ORX87268.1 - 0.15 11.9 0.0 0.49 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Pyridoxal_deC PF00282.19 ORX87269.1 - 1.3e-23 83.3 0.0 1.7e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 ORX87269.1 - 4.4e-10 39.4 0.1 7.3e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORX87269.1 - 7.4e-10 38.3 0.0 1.5e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 ORX87269.1 - 0.0075 15.0 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 ORX87269.1 - 0.031 12.8 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Dynamin_M PF01031.20 ORX87270.1 - 2.5e-107 358.4 0.1 5.2e-106 354.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORX87270.1 - 1.4e-55 188.0 1.8 3.8e-55 186.5 0.2 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 ORX87270.1 - 4.8e-33 113.2 5.6 2.7e-32 110.7 5.0 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORX87270.1 - 5.6e-05 23.2 0.3 0.00026 21.0 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX87270.1 - 0.068 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SOUL PF04832.12 ORX87270.1 - 0.07 13.3 0.7 0.16 12.2 0.7 1.5 1 0 0 1 1 1 0 SOUL heme-binding protein CDPS PF16715.5 ORX87270.1 - 0.13 11.9 1.6 2.5 7.7 0.0 2.9 2 1 1 3 3 3 0 Cyclodipeptide synthase KilA-N PF04383.13 ORX87271.1 - 6.2e-05 22.8 0.0 0.00088 19.1 0.0 2.0 1 1 0 1 1 1 1 KilA-N domain Cupin_7 PF12973.7 ORX87344.1 - 5.1e-37 125.7 0.2 2.1e-26 91.7 0.0 2.7 2 1 0 2 2 2 2 ChrR Cupin-like domain Cupin_2 PF07883.11 ORX87344.1 - 0.00045 19.9 2.7 0.017 14.9 0.7 2.6 2 1 0 2 2 2 2 Cupin domain DUF4437 PF14499.6 ORX87344.1 - 0.0057 15.8 0.3 0.12 11.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4437) RRM_1 PF00076.22 ORX87345.1 - 1e-29 102.1 0.9 2e-11 43.6 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 ORX87345.1 - 3.4e-08 33.5 0.0 0.00065 19.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 ORX87345.1 - 1.4e-07 31.3 0.0 0.11 12.4 0.0 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX87345.1 - 2.2e-05 24.5 0.2 0.8 9.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif DUF1866 PF08952.11 ORX87345.1 - 0.00015 21.6 0.1 5.1 6.9 0.0 4.0 2 2 2 4 4 4 1 Domain of unknown function (DUF1866) RRM_3 PF08777.11 ORX87345.1 - 0.0022 18.0 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nab6_mRNP_bdg PF10567.9 ORX87345.1 - 0.032 13.7 0.0 2 7.8 0.0 2.5 3 0 0 3 3 3 0 RNA-recognition motif Nup35_RRM_2 PF14605.6 ORX87345.1 - 0.065 13.2 0.0 38 4.4 0.0 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Lung_7-TM_R PF06814.13 ORX87346.1 - 1.4e-10 40.9 4.2 1.7e-10 40.6 4.2 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 ORX87346.1 - 0.0027 17.2 4.8 0.0029 17.1 4.8 1.0 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain SUI1 PF01253.22 ORX87347.1 - 9.8e-28 96.5 0.4 1.3e-27 96.1 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ig_3 PF13927.6 ORX87348.1 - 0.91 10.2 3.8 0.48 11.1 0.8 2.1 2 1 0 2 2 2 0 Immunoglobulin domain RINGv PF12906.7 ORX87349.1 - 5.9e-16 58.3 6.5 1.3e-15 57.2 6.5 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORX87349.1 - 0.017 15.4 8.2 0.033 14.5 8.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 ORX87349.1 - 1.3 9.1 3.5 2.5 8.2 3.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORX87349.1 - 4.6 7.1 7.2 8.3 6.3 7.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EST1_DNA_bind PF10373.9 ORX87350.1 - 1.9e-24 86.6 3.5 1.9e-24 86.6 3.5 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 ORX87350.1 - 1.3e-12 48.5 0.5 1e-11 45.6 0.5 2.6 1 1 0 1 1 1 1 Telomerase activating protein Est1 PIN_4 PF13638.6 ORX87350.1 - 2.1e-07 31.3 0.0 8e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 PIN domain zf-H2C2_2 PF13465.6 ORX87353.1 - 1.6e-22 78.9 27.6 4.2e-09 36.4 0.5 4.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX87353.1 - 2.9e-21 74.6 27.9 1.7e-05 25.0 1.0 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX87353.1 - 2.4e-12 46.6 25.2 0.012 16.4 0.4 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 ORX87353.1 - 4.2e-06 27.0 13.6 1.2 9.6 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX87353.1 - 5.3e-06 26.6 11.8 0.19 12.1 1.1 4.5 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORX87353.1 - 0.001 18.9 13.3 2.2 8.3 2.3 4.5 4 0 0 4 4 4 2 zinc-finger of a C2HC-type FOXP-CC PF16159.5 ORX87353.1 - 0.0012 19.5 10.9 0.19 12.4 0.6 3.3 2 1 2 4 4 4 2 FOXP coiled-coil domain Ogr_Delta PF04606.12 ORX87353.1 - 0.017 15.1 6.5 0.16 12.0 0.5 3.1 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger zf-TRAF PF02176.18 ORX87353.1 - 0.12 13.1 9.1 0.27 11.9 3.9 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 ORX87353.1 - 0.26 11.1 13.1 0.97 9.2 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-CGNR PF11706.8 ORX87353.1 - 0.3 11.0 8.9 8.9 6.3 2.9 3.4 2 1 1 3 3 3 0 CGNR zinc finger zf-LYAR PF08790.11 ORX87353.1 - 0.53 10.2 13.8 3.6 7.6 0.1 4.6 4 1 0 4 4 4 0 LYAR-type C2HC zinc finger Toxin_8 PF07365.12 ORX87353.1 - 8.2 6.7 9.1 16 5.7 0.2 3.1 3 0 0 3 3 3 0 Alpha conotoxin precursor Oxysterol_BP PF01237.18 ORX87354.1 - 2.5e-144 480.7 0.1 4e-144 480.0 0.1 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 ORX87354.1 - 5.1e-20 71.9 5.2 7e-10 39.4 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX87354.1 - 3.5e-15 56.2 0.5 1.3e-06 28.8 0.2 4.1 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX87354.1 - 1e-14 54.3 0.1 2e-06 27.9 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 ORX87354.1 - 4e-14 53.0 0.5 1e-12 48.5 0.0 2.8 2 0 0 2 2 2 1 PH domain Ank_3 PF13606.6 ORX87354.1 - 4.5e-14 51.2 0.6 3.8e-05 23.8 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.30 ORX87354.1 - 4.6e-10 39.5 0.4 0.0013 19.1 0.1 3.8 3 1 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 ORX87354.1 - 1.1e-07 32.0 0.8 3e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 ORX87354.1 - 0.00033 21.1 0.3 0.00033 21.1 0.3 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain Ribosomal_60s PF00428.19 ORX87355.1 - 0.093 13.3 0.4 0.093 13.3 0.4 3.2 2 1 1 3 3 3 0 60s Acidic ribosomal protein SLC12 PF03522.15 ORX87355.1 - 2.1 7.3 12.2 3 6.7 12.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 KilA-N PF04383.13 ORX87356.1 - 3.1e-05 23.8 0.0 0.00044 20.1 0.0 2.0 1 1 0 1 1 1 1 KilA-N domain PH_14 PF17787.1 ORX87356.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 PH domain DLIC PF05783.11 ORX87357.1 - 5.8e-73 246.3 11.7 7.1e-65 219.7 0.3 4.9 2 2 1 3 3 3 3 Dynein light intermediate chain (DLIC) Roc PF08477.13 ORX87357.1 - 5.7e-05 23.3 0.2 0.0015 18.8 0.0 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORX87357.1 - 0.0005 20.5 0.0 0.002 18.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 ORX87357.1 - 0.0024 17.3 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORX87357.1 - 0.0034 17.3 0.1 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORX87357.1 - 0.0034 16.9 0.1 0.22 11.0 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX87357.1 - 0.007 16.4 0.1 0.018 15.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 ORX87357.1 - 0.0096 15.3 0.0 0.036 13.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein G-alpha PF00503.20 ORX87357.1 - 0.028 13.6 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 ORX87357.1 - 0.07 13.7 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 ORX87357.1 - 0.093 13.3 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORX87357.1 - 0.11 12.2 0.0 0.5 10.1 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PPR_2 PF13041.6 ORX87358.1 - 2.5e-130 424.6 34.5 8.8e-14 51.4 0.0 15.7 5 2 11 16 16 16 15 PPR repeat family PPR PF01535.20 ORX87358.1 - 3.9e-96 308.8 38.7 5.7e-08 32.5 0.1 19.7 19 1 0 19 19 19 16 PPR repeat PPR_1 PF12854.7 ORX87358.1 - 1.1e-94 309.8 8.6 5.3e-11 42.0 0.5 17.6 17 1 0 17 17 17 13 PPR repeat PPR_3 PF13812.6 ORX87358.1 - 1.2e-64 214.2 10.9 5.7e-10 39.1 0.0 11.7 5 3 8 16 16 14 13 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX87358.1 - 9.1e-45 152.6 2.9 4.2e-12 45.9 0.2 7.3 1 1 6 7 7 7 6 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 ORX87358.1 - 2.4e-08 33.8 2.3 3.4 7.6 0.0 8.2 6 1 4 10 10 10 1 Mitochondrial ATPase expression RPM2 PF08579.11 ORX87358.1 - 8.8e-06 26.1 11.3 2.5 8.5 0.1 8.4 4 2 3 8 8 7 2 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX87358.1 - 1.2e-05 24.4 1.0 0.0055 15.6 0.0 4.1 3 2 0 4 4 4 1 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.11 ORX87358.1 - 0.00012 21.2 0.7 2.4 7.2 0.0 5.0 3 2 3 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_19 PF14559.6 ORX87358.1 - 0.00022 21.6 0.1 22 5.6 0.0 6.5 8 1 1 9 9 8 0 Tetratricopeptide repeat Clathrin PF00637.20 ORX87358.1 - 0.0019 18.1 5.2 20 5.0 0.1 5.9 5 1 1 7 7 7 0 Region in Clathrin and VPS TPR_7 PF13176.6 ORX87358.1 - 0.015 15.3 1.5 25 5.2 0.0 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat BTAD PF03704.17 ORX87358.1 - 0.03 14.8 0.5 30 5.0 0.0 4.3 4 1 1 5 5 5 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 ORX87358.1 - 0.049 13.9 0.8 6.2 7.2 0.2 4.7 4 1 0 4 4 3 0 Tetratricopeptide repeat Hemocyanin_N PF03722.14 ORX87358.1 - 0.15 12.6 0.6 2 8.9 0.3 3.1 3 0 0 3 3 2 0 Hemocyanin, all-alpha domain Glyco_hydro_20 PF00728.22 ORX87359.1 - 4.7e-93 312.4 2.8 5.7e-93 312.1 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORX87359.1 - 4.7e-13 50.0 0.0 1.3e-12 48.6 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Peptidase_M28 PF04389.17 ORX87360.1 - 1.4e-38 132.6 0.0 2.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX87360.1 - 8.7e-15 54.5 0.3 2e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX87360.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SRF-TF PF00319.18 ORX87424.1 - 4.9e-21 74.0 0.1 7.1e-21 73.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HSF_DNA-bind PF00447.17 ORX87425.1 - 1.6e-31 108.7 3.7 1.6e-31 108.7 3.7 2.3 3 0 0 3 3 3 1 HSF-type DNA-binding Response_reg PF00072.24 ORX87425.1 - 4.4e-24 84.8 0.1 1.1e-23 83.5 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 ORX87425.1 - 0.074 13.5 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Ets-domain AATF-Che1 PF13339.6 ORX87425.1 - 0.59 10.8 2.8 1.5 9.5 2.8 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DEAD PF00270.29 ORX87426.1 - 1e-48 165.4 0.0 1.7e-46 158.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX87426.1 - 1.8e-32 112.0 0.1 1.8e-32 112.0 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX87426.1 - 1.7e-05 24.9 0.2 0.0007 19.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX87426.1 - 0.13 12.6 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain GFRP PF06399.13 ORX87426.1 - 0.17 11.8 0.0 14 5.6 0.0 2.7 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Rubella_Capsid PF05750.11 ORX87426.1 - 8.7 5.8 14.2 17 4.9 14.2 1.4 1 0 0 1 1 1 0 Rubella capsid protein LSM PF01423.22 ORX87428.1 - 3.5e-19 68.2 0.1 3.9e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX87428.1 - 4.4e-05 23.5 0.0 5.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORX87428.1 - 0.069 13.2 0.1 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain ELK PF03789.13 ORX87428.1 - 0.38 10.9 1.4 22 5.3 0.1 2.4 2 0 0 2 2 2 0 ELK domain NatB_MDM20 PF09797.9 ORX87429.1 - 1.4e-95 320.5 7.9 1.4e-95 320.5 7.9 2.9 4 0 0 4 4 4 1 N-acetyltransferase B complex (NatB) non catalytic subunit ANAPC3 PF12895.7 ORX87429.1 - 0.0025 18.0 4.3 0.89 9.8 0.3 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORX87429.1 - 0.0029 17.9 6.2 1.1 9.6 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX87429.1 - 0.084 13.4 6.2 0.29 11.7 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORX87429.1 - 0.11 12.1 0.5 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 ORX87429.1 - 0.19 11.8 1.0 0.92 9.6 0.5 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat EF-G-binding_N PF07299.11 ORX87429.1 - 6.8 7.3 16.3 0.1 13.1 0.6 5.0 5 1 1 6 6 6 0 Elongation factor G-binding protein, N-terminal PBD PF00786.28 ORX87430.1 - 6.3e-05 23.3 0.7 0.00042 20.6 0.1 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase PF00069.25 ORX87431.1 - 4e-72 242.8 0.0 4.7e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX87431.1 - 7.4e-53 179.5 0.0 9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX87431.1 - 1.8e-06 27.5 0.0 0.00065 19.1 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORX87431.1 - 3e-05 23.0 0.0 4.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX87431.1 - 0.00069 18.7 0.0 0.48 9.3 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain HLH PF00010.26 ORX87432.1 - 5.1e-12 45.6 0.6 1.1e-11 44.5 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 ORX87432.1 - 0.005 17.0 0.3 0.005 17.0 0.3 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Med10 PF09748.9 ORX87432.1 - 0.059 13.3 0.2 0.096 12.7 0.2 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex FHA PF00498.26 ORX87433.1 - 5.5e-20 71.5 0.1 9.6e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORX87433.1 - 3e-09 37.0 0.0 6.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain dsrm PF00035.26 ORX87433.1 - 4.5e-07 30.5 1.6 4.7e-07 30.4 0.0 2.0 2 0 0 2 2 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 ORX87433.1 - 0.0024 18.0 0.3 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Peptidase_C6 PF00851.18 ORX87433.1 - 0.0055 15.7 1.6 0.0081 15.1 1.6 1.1 1 0 0 1 1 1 1 Helper component proteinase VPS38 PF17649.1 ORX87433.1 - 0.028 13.3 4.1 0.044 12.7 4.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 CH_2 PF06294.11 ORX87433.1 - 0.062 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Mod_r PF07200.13 ORX87433.1 - 0.082 13.0 8.2 0.18 11.9 8.2 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Stm1_N PF09598.10 ORX87433.1 - 0.13 13.1 0.5 0.13 13.1 0.5 4.0 3 1 1 4 4 3 0 Stm1 DUF3450 PF11932.8 ORX87433.1 - 0.14 11.4 6.3 0.26 10.5 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FAD-SLDH PF12318.8 ORX87433.1 - 0.64 10.1 1.9 2.4 8.2 0.4 2.2 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF1664 PF07889.12 ORX87433.1 - 0.89 9.6 4.3 3.1 7.9 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ORX87433.1 - 1.6 8.9 9.9 4.9 7.3 9.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.16 ORX87434.1 - 6e-44 150.4 31.2 7.4e-44 150.1 31.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_9 PF13527.7 ORX87435.1 - 9.1e-08 32.2 0.0 1.6e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX87435.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 ORX87435.1 - 0.0041 16.6 0.0 0.0082 15.6 0.0 1.5 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_10 PF13673.7 ORX87435.1 - 0.0058 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX87435.1 - 0.015 15.7 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX87435.1 - 0.021 14.9 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PEX11 PF05648.14 ORX87436.1 - 4.5e-24 85.2 0.4 5.6e-24 84.9 0.4 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HTH_psq PF05225.16 ORX87436.1 - 0.11 12.3 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Glyco_trans_1_3 PF13528.6 ORX87437.1 - 2.1e-05 24.0 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 HLH PF00010.26 ORX87517.1 - 1.4e-15 56.9 3.9 1.4e-15 56.9 3.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.18 ORX87517.1 - 0.14 12.5 0.3 0.36 11.2 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family ZapB PF06005.12 ORX87517.1 - 0.22 12.0 4.3 0.61 10.6 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Copper-fist PF00649.18 ORX87518.1 - 6.8e-23 79.9 1.9 6.8e-23 79.9 1.9 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain Pyr_redox_2 PF07992.14 ORX87520.1 - 1.6e-47 162.2 0.0 2.3e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX87520.1 - 1.4e-15 57.6 0.0 7.1e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 ORX87520.1 - 7.4e-12 43.9 3.9 1.8e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORX87520.1 - 2e-11 42.8 2.8 3.4e-05 23.4 0.8 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORX87520.1 - 1.1e-10 40.4 3.1 1.9e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ORX87520.1 - 9.3e-09 35.6 10.4 2.7e-07 30.9 3.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX87520.1 - 7.9e-06 25.6 1.3 0.16 11.8 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 ORX87520.1 - 0.00079 18.8 1.0 0.81 8.9 2.5 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX87520.1 - 0.15 12.3 0.0 34 4.8 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Cyclin_N PF00134.23 ORX87521.1 - 1.7e-17 63.3 0.1 2.5e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORX87521.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Aa_trans PF01490.18 ORX87522.1 - 1.8e-30 106.0 18.0 3.2e-30 105.2 18.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 ORX87523.1 - 1e-52 179.3 46.2 1e-52 179.3 46.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX87523.1 - 6.4e-15 54.6 24.5 1.2e-14 53.7 24.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX87523.1 - 6.9e-15 54.9 13.3 6.9e-15 54.9 13.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2527 PF10736.9 ORX87523.1 - 0.14 12.0 0.3 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DJ-1_PfpI PF01965.24 ORX87524.1 - 4e-22 78.8 0.0 4.7e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX87524.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase_5 PF13507.6 ORX87524.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Synaptobrevin PF00957.21 ORX87525.1 - 1.9e-33 114.1 1.5 2e-33 114.0 1.5 1.0 1 0 0 1 1 1 1 Synaptobrevin CD34_antigen PF06365.12 ORX87525.1 - 0.017 14.8 0.4 0.021 14.4 0.4 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family MCU PF04678.13 ORX87525.1 - 0.028 14.5 0.1 0.032 14.3 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RIFIN PF02009.16 ORX87525.1 - 0.066 13.1 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Rifin Herpes_teg_N PF04843.12 ORX87525.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Fzo_mitofusin PF04799.13 ORX87525.1 - 0.2 11.2 1.4 0.21 11.1 0.9 1.3 1 1 0 1 1 1 0 fzo-like conserved region UPF0258 PF06789.12 ORX87525.1 - 0.63 10.2 3.7 0.72 10.0 3.6 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) Sds3 PF08598.11 ORX87526.1 - 2.1e-20 73.6 18.9 3.9e-20 72.8 18.9 1.4 1 1 0 1 1 1 1 Sds3-like E2_bind PF08825.10 ORX87526.1 - 0.44 10.7 3.9 0.26 11.4 0.8 2.1 2 0 0 2 2 2 0 E2 binding domain SAPS PF04499.15 ORX87527.1 - 0.0089 14.9 0.1 0.0097 14.7 0.1 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Arm PF00514.23 ORX87527.1 - 0.011 15.8 0.7 1.6 8.8 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 ORX87527.1 - 0.034 13.7 0.7 0.29 10.7 0.1 1.9 1 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II mRNA_stabil PF13929.6 ORX87527.1 - 0.08 11.9 0.3 0.098 11.6 0.3 1.1 1 0 0 1 1 1 0 mRNA stabilisation DUF1773 PF08593.10 ORX87527.1 - 0.12 13.4 0.1 0.35 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function TPR_2 PF07719.17 ORX87528.1 - 6.3e-13 47.8 2.2 0.00046 20.1 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX87528.1 - 4.6e-12 45.2 3.3 0.00091 18.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX87528.1 - 1.7e-08 34.8 1.5 1.7e-07 31.6 0.5 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORX87528.1 - 1.4e-07 31.5 1.0 2.1e-07 31.0 1.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX87528.1 - 2.4e-07 31.3 0.1 1.3e-05 25.8 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORX87528.1 - 2.4e-07 30.7 1.3 3.6e-05 23.8 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX87528.1 - 2.7e-07 30.9 0.7 0.00017 22.1 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX87528.1 - 9.4e-07 28.4 0.1 0.056 13.1 0.0 3.4 2 1 1 3 3 3 3 TPR repeat ANAPC3 PF12895.7 ORX87528.1 - 2.2e-06 27.8 0.8 4e-05 23.8 0.2 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORX87528.1 - 1.5e-05 25.3 0.8 0.045 14.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX87528.1 - 7.2e-05 22.6 0.0 0.9 9.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX87528.1 - 9.1e-05 22.4 0.7 0.11 12.7 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX87528.1 - 0.00024 21.3 1.1 0.0027 17.9 0.6 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORX87528.1 - 0.0019 18.5 3.1 0.023 15.0 3.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat Spo7 PF03907.13 ORX87528.1 - 0.016 14.7 0.7 0.022 14.2 0.7 1.2 1 0 0 1 1 1 0 Spo7-like protein Fis1_TPR_C PF14853.6 ORX87528.1 - 0.017 15.2 0.5 0.31 11.1 0.0 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ORX87528.1 - 0.022 14.6 2.5 4.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_5 PF07994.12 ORX87529.1 - 4.8e-145 482.9 0.1 5.6e-145 482.7 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORX87529.1 - 6e-46 155.2 0.3 1.3e-45 154.1 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FAM104 PF15434.6 ORX87530.1 - 0.059 13.9 3.0 0.89 10.1 0.5 2.8 2 1 1 3 3 3 0 Family 104 GlcNAc PF11397.8 ORX87530.1 - 0.081 12.4 0.0 0.096 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) 4HBT PF03061.22 ORX87532.1 - 0.00037 20.8 0.0 0.33 11.3 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Ion_trans PF00520.31 ORX87533.1 - 3.3e-153 507.9 80.7 5.1e-47 160.2 11.0 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 ORX87533.1 - 2.7e-05 23.8 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF4173 PF13777.6 ORX87534.1 - 0.088 12.2 2.3 0.12 11.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) TMEM154 PF15102.6 ORX87534.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Radical_SAM PF04055.21 ORX87535.1 - 3.1e-15 57.0 0.0 5.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ORX87535.1 - 3.1e-05 24.1 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Rrn6 PF10214.9 ORX87536.1 - 8.2e-21 74.3 23.8 9.9e-21 74.0 20.3 2.7 2 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor CENP-K PF11802.8 ORX87537.1 - 1e-29 104.0 5.0 1.2e-29 103.7 5.0 1.1 1 0 0 1 1 1 1 Centromere-associated protein K DUF4164 PF13747.6 ORX87537.1 - 0.0022 18.2 15.5 0.013 15.7 3.5 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) Cor1 PF04803.12 ORX87537.1 - 0.0082 16.4 6.1 0.23 11.7 3.5 2.5 2 1 0 2 2 2 1 Cor1/Xlr/Xmr conserved region Exonuc_VII_L PF02601.15 ORX87537.1 - 0.043 13.4 2.9 0.057 13.0 2.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 ORX87537.1 - 0.049 14.1 1.5 0.049 14.1 1.5 3.3 2 1 1 3 3 3 0 Snapin/Pallidin Macoilin PF09726.9 ORX87537.1 - 0.61 8.6 8.5 0.85 8.1 8.5 1.2 1 0 0 1 1 1 0 Macoilin family AAA_23 PF13476.6 ORX87537.1 - 0.78 10.2 5.7 1.2 9.6 5.7 1.4 1 0 0 1 1 1 0 AAA domain HCMV_UL139 PF12507.8 ORX87537.1 - 0.97 9.8 5.3 53 4.2 5.3 2.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein Occludin_ELL PF07303.13 ORX87537.1 - 5.2 7.8 8.2 1.8 9.4 1.3 2.7 1 1 2 3 3 3 0 Occludin homology domain TPR_MLP1_2 PF07926.12 ORX87537.1 - 5.8 7.0 16.3 8.3 6.5 14.3 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 ORX87537.1 - 6.9 6.7 15.0 29 4.7 10.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.13 ORX87537.1 - 7.9 6.6 10.3 0.56 10.3 2.4 2.4 2 1 0 2 2 2 0 DivIVA protein FapA PF03961.13 ORX87537.1 - 8 4.9 6.7 5.6 5.4 5.1 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 ORX87537.1 - 8.2 6.5 13.3 2.2 8.4 4.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 ORX87537.1 - 8.5 7.1 12.8 1.6 9.4 3.3 3.1 2 1 1 3 3 3 0 SlyX Cep57_CLD_2 PF14197.6 ORX87537.1 - 8.5 6.6 17.8 16 5.7 1.3 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 ORX87538.1 - 0 1042.0 0.0 0 1041.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1471 PF07338.13 ORX87538.1 - 0.0011 18.9 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1471) DUF4052 PF13261.6 ORX87538.1 - 1 9.2 8.4 0.24 11.2 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4052) Methyltrn_RNA_3 PF02598.17 ORX87540.1 - 9.4e-100 333.8 0.0 1.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Redoxin PF08534.10 ORX87541.1 - 1.1e-37 129.0 0.1 1.2e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORX87541.1 - 2e-10 40.7 0.0 2.2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Tetraspanin PF00335.20 ORX87542.1 - 2.5e-05 24.1 16.6 2.5e-05 24.1 16.6 1.9 1 1 0 1 1 1 1 Tetraspanin family DUF2070 PF09843.9 ORX87542.1 - 7.7 4.7 10.1 10 4.3 10.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sod_Cu PF00080.20 ORX87624.1 - 2.4e-23 82.9 3.2 2.7e-23 82.7 3.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 ORX87624.1 - 0.014 16.4 0.7 0.016 16.2 0.7 1.1 1 0 0 1 1 1 0 CHRD domain DcpS_C PF11969.8 ORX87625.1 - 1.4e-29 102.8 1.6 2.6e-29 102.0 1.6 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 ORX87625.1 - 7.7e-26 91.0 0.1 1.3e-25 90.2 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Capsid_NCLDV PF04451.12 ORX87625.1 - 0.16 11.8 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein DNA_topoisoIV PF00521.20 ORX87626.1 - 8.4e-131 436.8 0.5 2.1e-130 435.5 0.5 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORX87626.1 - 1.7e-49 167.3 4.5 1.7e-49 167.3 4.5 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORX87626.1 - 1.1e-27 96.7 5.8 2.8e-27 95.3 5.8 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 ORX87626.1 - 7.1e-14 52.3 0.6 1.9e-13 50.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORX87626.1 - 3.8e-09 36.7 0.0 1.3e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain IF-2B PF01008.17 ORX87627.1 - 6.6e-86 288.0 0.1 8.2e-86 287.7 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Spt20 PF12090.8 ORX87627.1 - 4.8 6.7 7.5 7.1 6.2 7.5 1.2 1 0 0 1 1 1 0 Spt20 family Sod_Cu PF00080.20 ORX87628.1 - 9.7e-35 119.8 3.1 1.8e-34 118.9 3.1 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 ORX87628.1 - 1.7e-16 60.4 0.2 2.9e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain PGM_PMM_IV PF00408.20 ORX87628.1 - 0.052 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF411 PF04214.13 ORX87628.1 - 0.09 12.7 0.1 0.38 10.7 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF EFG_C PF00679.24 ORX87628.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G C-terminus Mito_fiss_reg PF05308.11 ORX87629.1 - 1.5e-05 25.3 5.2 1.5e-05 25.3 5.2 2.4 2 0 0 2 2 2 1 Mitochondrial fission regulator Med30 PF11315.8 ORX87629.1 - 0.14 12.3 0.6 2 8.6 0.0 2.8 3 0 0 3 3 3 0 Mediator complex subunit 30 DUF4955 PF16315.5 ORX87630.1 - 5.1e-05 23.5 0.0 0.00026 21.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4955) Pectate_lyase_3 PF12708.7 ORX87630.1 - 0.00013 21.9 0.7 0.00043 20.2 0.1 2.0 2 0 0 2 2 2 1 Pectate lyase superfamily protein hDGE_amylase PF14701.6 ORX87631.1 - 1.8e-169 564.5 0.0 2.7e-169 563.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ORX87631.1 - 3.4e-117 391.6 0.0 5.5e-117 390.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ORX87631.1 - 4.2e-79 265.8 0.0 9.6e-79 264.6 0.0 1.6 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 ORX87631.1 - 2.2e-21 75.8 0.1 7.2e-21 74.1 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF445 PF04286.12 ORX87631.1 - 0.017 15.0 0.0 0.056 13.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Phi-29_GP3 PF05435.11 ORX87631.1 - 0.12 11.8 0.3 0.2 11.1 0.3 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 MFS_1 PF07690.16 ORX87632.1 - 6.5e-39 133.9 42.3 1.8e-31 109.4 20.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX87632.1 - 0.00023 19.7 6.2 0.0015 17.0 1.5 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX87632.1 - 0.00038 19.4 19.7 0.0059 15.5 3.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORX87632.1 - 0.02 13.8 10.0 1.1 8.1 4.3 3.6 2 2 0 2 2 2 0 MFS_1 like family FtsL PF04999.13 ORX87633.1 - 0.26 11.3 2.2 3.3 7.8 0.5 2.9 2 0 0 2 2 2 0 Cell division protein FtsL TMEM100 PF16311.5 ORX87633.1 - 4.8 6.8 7.2 0.76 9.4 0.5 2.4 2 0 0 2 2 2 0 Transmembrane protein 100 CNH PF00780.22 ORX87634.1 - 1.8e-77 260.7 0.0 3.4e-77 259.7 0.0 1.5 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORX87634.1 - 4.1e-39 134.7 2.6 1.5e-37 129.6 0.2 2.9 2 1 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 ORX87634.1 - 7.8e-32 110.2 0.0 7.8e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 ORX87634.1 - 3.9e-14 52.4 0.0 9.8e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 ORX87634.1 - 0.015 15.1 2.6 0.4 10.5 2.6 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 ORX87634.1 - 0.016 15.7 0.0 0.064 13.8 0.0 2.1 1 1 0 1 1 1 0 PH domain PH_10 PF15411.6 ORX87634.1 - 0.055 13.7 0.0 0.39 11.0 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 ORX87634.1 - 0.15 11.9 0.1 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 PH domain Tubulin PF00091.25 ORX87635.1 - 2.1e-70 236.9 0.0 3.7e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX87635.1 - 3.9e-42 143.4 0.0 6.7e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX87635.1 - 2.9e-05 24.4 0.4 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORX87635.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORX87635.1 - 0.024 13.8 0.1 0.09 11.9 0.0 1.8 2 0 0 2 2 2 0 Tubulin like TPT PF03151.16 ORX87636.1 - 1.2e-08 34.7 19.2 1.6e-08 34.2 19.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORX87636.1 - 7.2e-08 32.7 25.9 8.6e-07 29.2 7.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORX87636.1 - 1.3e-05 24.6 23.1 2.4e-05 23.7 23.1 1.5 1 1 0 1 1 1 1 UAA transporter family PHO4 PF01384.20 ORX87636.1 - 1.6 7.7 19.1 0.81 8.7 3.7 2.6 1 1 1 3 3 3 0 Phosphate transporter family DUF2070 PF09843.9 ORX87636.1 - 3 6.0 19.8 0.036 12.4 9.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Arrestin_C PF02752.22 ORX87637.1 - 2e-11 44.5 3.4 3.2e-09 37.3 0.7 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX87637.1 - 0.016 15.3 0.5 0.2 11.7 0.0 2.7 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Laminin_G_1 PF00054.23 ORX87637.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 Laminin G domain Reeler PF02014.16 ORX87638.1 - 6e-07 30.3 0.0 7e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Reeler domain CBAH PF02275.18 ORX87640.1 - 0.015 15.0 0.3 0.019 14.6 0.3 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family SAP PF02037.27 ORX87723.1 - 0.07 12.9 0.3 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 SAP domain DUF896 PF05979.12 ORX87723.1 - 0.33 10.8 4.1 0.89 9.5 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) Cyt_bd_oxida_II PF02322.15 ORX87724.1 - 0.00094 18.6 2.9 0.001 18.5 2.9 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Glucan_synthase PF02364.15 ORX87725.1 - 0 1226.7 0.0 0 1226.0 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORX87725.1 - 4.3e-39 133.8 0.9 1.7e-38 131.8 0.9 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Myb_DNA-bind_4 PF13837.6 ORX87726.1 - 3.9e-16 59.2 5.4 5.2e-16 58.8 1.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX87726.1 - 3.7e-05 23.9 1.0 3.7e-05 23.9 1.0 2.0 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX87726.1 - 0.0011 19.1 2.1 0.0037 17.4 2.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX87726.1 - 0.015 15.6 0.3 0.015 15.6 0.3 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ATG16 PF08614.11 ORX87726.1 - 0.044 14.0 1.4 0.083 13.1 1.4 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Myb_DNA-bind_3 PF12776.7 ORX87726.1 - 0.1 13.6 3.4 0.22 12.5 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Glucan_synthase PF02364.15 ORX87727.1 - 0 1208.4 0.0 0 1208.4 0.0 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORX87727.1 - 2.3e-37 128.2 2.2 7.9e-37 126.5 2.2 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TIMP PF00965.17 ORX87727.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase HA2 PF04408.23 ORX87728.1 - 1.6e-24 86.3 0.0 3.3e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORX87728.1 - 2e-14 53.7 0.0 3.8e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORX87728.1 - 1.7e-13 50.9 0.1 7.6e-13 48.8 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORX87728.1 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase W2 PF02020.18 ORX87729.1 - 2e-20 72.7 3.5 5.1e-20 71.4 3.5 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 ORX87729.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORX87729.1 - 1.2e-10 40.6 16.6 8.8e-07 28.4 5.3 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORX87729.1 - 2.5e-05 24.7 0.0 4.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORX87729.1 - 0.00034 20.3 12.0 0.0022 17.7 4.9 3.9 1 1 2 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORX87729.1 - 0.0022 16.2 1.0 0.0037 15.5 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 ORX87729.1 - 0.0091 15.0 0.6 0.05 12.5 0.4 2.2 2 0 0 2 2 2 1 L-fucokinase Glycos_transf_1 PF00534.20 ORX87730.1 - 9.7e-13 48.0 0.0 1.6e-10 40.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX87730.1 - 3.4e-12 46.9 0.0 8.6e-11 42.4 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORX87730.1 - 0.0025 18.2 0.0 0.25 11.7 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 ELO PF01151.18 ORX87731.1 - 6.1e-60 202.8 23.0 7.5e-60 202.5 23.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Methyltransf_16 PF10294.9 ORX87732.1 - 1.2e-25 90.2 0.2 9.7e-11 41.7 0.0 3.3 3 1 0 3 3 3 3 Lysine methyltransferase MTS PF05175.14 ORX87732.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Gti1_Pac2 PF09729.9 ORX87733.1 - 3.2e-46 157.7 4.3 1.4e-39 136.1 0.5 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Arm PF00514.23 ORX87734.1 - 0.0031 17.5 0.1 0.093 12.8 0.0 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Sigma54_AID PF00309.20 ORX87734.1 - 0.045 13.6 1.8 2 8.3 0.1 3.1 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) WD40 PF00400.32 ORX87735.1 - 3.5e-10 40.3 9.8 0.00056 20.7 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat PYST-C1 PF09690.10 ORX87735.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) ANAPC4_WD40 PF12894.7 ORX87735.1 - 0.071 13.4 2.6 1.7 9.0 0.3 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain UCH PF00443.29 ORX87736.1 - 2.4e-74 250.1 0.1 4.2e-74 249.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX87736.1 - 2.7e-20 73.2 0.0 3.8e-19 69.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 ORX87736.1 - 4.6e-12 46.1 3.3 8.7e-12 45.2 3.3 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 ORX87736.1 - 4.3e-07 30.4 0.0 1.1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C98 PF15499.6 ORX87736.1 - 0.0035 16.8 1.3 0.011 15.3 0.7 2.0 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase FmiP_Thoc5 PF09766.9 ORX87737.1 - 4.6e-36 124.9 16.2 6.4e-36 124.4 16.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DivIC PF04977.15 ORX87737.1 - 3.4 7.5 9.2 0.11 12.3 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator TatD_DNase PF01026.21 ORX87738.1 - 5.7e-38 130.7 0.0 7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF4451 PF14616.6 ORX87739.1 - 8.7e-26 90.5 0.7 1.1e-25 90.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) PHD_2 PF13831.6 ORX87740.1 - 7e-10 38.3 5.1 7e-10 38.3 5.1 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 ORX87740.1 - 5.2e-08 32.7 11.4 7.5e-08 32.2 11.4 1.2 1 0 0 1 1 1 1 PHD-finger Mito_carr PF00153.27 ORX87740.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein FYVE_2 PF02318.16 ORX87740.1 - 0.42 10.8 5.2 0.48 10.6 4.5 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 ORX87740.1 - 2.3 8.6 9.5 3.4 8.1 6.3 2.1 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 ORX87740.1 - 5 7.1 10.5 1.1 9.2 4.7 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MCM PF00493.23 ORX87741.1 - 1e-97 325.6 0.2 2e-97 324.7 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORX87741.1 - 3.7e-36 123.7 0.0 7.3e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORX87741.1 - 4e-21 75.2 0.3 9.5e-21 74.0 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORX87741.1 - 3.9e-13 49.9 0.7 1.1e-12 48.5 0.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORX87741.1 - 8.9e-09 35.0 0.2 2.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORX87741.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 ORX87741.1 - 0.0085 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX87741.1 - 0.039 14.0 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RcpC PF16976.5 ORX87741.1 - 0.062 13.4 0.1 0.062 13.4 0.1 2.1 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB Smg8_Smg9 PF10220.9 ORX87827.1 - 6.8e-21 74.4 7.4 5.5e-12 44.9 0.1 3.2 2 1 0 2 2 2 2 Smg8_Smg9 Hist_deacetyl PF00850.19 ORX87828.1 - 7e-83 278.6 0.1 1.5e-82 277.6 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain UQ_con PF00179.26 ORX87830.1 - 2.5e-44 150.3 0.1 4.3e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORX87830.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 UEV domain Ank_4 PF13637.6 ORX87831.1 - 2.5e-14 53.4 0.0 5.6e-11 42.7 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX87831.1 - 3.1e-14 53.3 0.0 2.5e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX87831.1 - 3.3e-13 49.6 0.1 2.5e-07 30.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORX87831.1 - 1e-12 47.9 0.8 7.2e-05 23.1 0.1 3.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ORX87831.1 - 7e-12 44.4 0.1 1.6e-05 24.9 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Nup54 PF13874.6 ORX87831.1 - 0.038 14.1 0.9 0.066 13.3 0.9 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 PHD PF00628.29 ORX87832.1 - 2e-08 34.0 9.2 3.5e-08 33.2 9.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORX87832.1 - 0.0002 20.9 8.5 0.0002 20.9 8.5 1.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 ORX87832.1 - 0.65 9.6 6.3 0.14 11.7 1.4 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain API5 PF05918.11 ORX87832.1 - 1.6 7.5 7.2 2.5 6.8 7.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF5320 PF17253.2 ORX87832.1 - 3.1 8.9 12.2 2.7 9.1 9.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ribosomal_S13_N PF08069.12 ORX87833.1 - 2e-30 104.6 0.0 3.7e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORX87833.1 - 2.9e-13 49.8 0.6 4.5e-13 49.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 DEAD PF00270.29 ORX87834.1 - 8.1e-40 136.4 0.0 1.3e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX87834.1 - 3.3e-31 107.9 0.0 1e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF816 PF05674.12 ORX87834.1 - 0.073 13.0 0.9 0.14 12.1 0.9 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Pex26 PF07163.12 ORX87835.1 - 0.0011 18.4 0.1 0.063 12.6 0.0 2.7 3 0 0 3 3 3 2 Pex26 protein Pex14_N PF04695.13 ORX87835.1 - 0.0092 16.6 1.5 0.0092 16.6 1.5 1.5 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SPC25 PF06703.11 ORX87836.1 - 1.7e-46 158.0 0.7 2e-46 157.8 0.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_U4 PF03419.13 ORX87836.1 - 0.045 13.0 0.5 0.063 12.6 0.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Glyco_hydro_16 PF00722.21 ORX87837.1 - 8.3e-34 116.6 4.6 1.2e-33 116.1 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Toxin_18 PF08087.11 ORX87837.1 - 0.52 10.3 8.6 1 9.4 8.6 1.4 1 0 0 1 1 1 0 Conotoxin O-superfamily Chitin_bind_1 PF00187.19 ORX87837.1 - 0.61 10.6 10.1 1.4 9.5 10.1 1.5 1 0 0 1 1 1 0 Chitin recognition protein 6PF2K PF01591.18 ORX87838.1 - 6.2e-72 241.5 0.0 9.1e-72 241.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORX87838.1 - 4e-20 72.3 0.0 6.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORX87838.1 - 6.1e-06 26.5 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Aa_trans PF01490.18 ORX87841.1 - 5.8e-66 222.9 36.3 6.6e-66 222.7 36.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORX87841.1 - 0.0045 15.9 50.4 0.034 13.0 50.4 2.0 1 1 0 1 1 1 1 Amino acid permease zf-C2H2_jaz PF12171.8 ORX87842.1 - 0.0078 16.5 1.5 0.011 16.0 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX87842.1 - 0.016 15.6 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AF-4 PF05110.13 ORX87842.1 - 0.63 8.1 31.2 0.77 7.8 31.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SDA1 PF05285.12 ORX87842.1 - 0.69 9.3 44.9 0.87 9.0 44.9 1.1 1 0 0 1 1 1 0 SDA1 Guanylate_kin PF00625.21 ORX87843.1 - 2.7e-65 219.5 0.0 3e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 ORX87843.1 - 4.5e-06 27.2 0.0 6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX87843.1 - 2.4e-05 24.8 0.1 3.3e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORX87843.1 - 2.5e-05 24.4 0.1 0.00015 22.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX87843.1 - 0.00014 22.1 0.0 0.0003 21.1 0.0 1.5 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 ORX87843.1 - 0.0008 19.5 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ORX87843.1 - 0.0011 19.2 0.1 0.0021 18.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 ORX87843.1 - 0.0014 19.2 0.1 0.0015 19.0 0.1 1.5 1 1 0 1 1 1 1 ABC transporter T2SSE PF00437.20 ORX87843.1 - 0.0021 17.2 0.0 0.0045 16.1 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORX87843.1 - 0.0025 17.3 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ORX87843.1 - 0.0038 17.2 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 ORX87843.1 - 0.0051 17.2 0.0 0.0093 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 ORX87843.1 - 0.0052 16.5 0.7 0.0099 15.6 0.3 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain DUF2075 PF09848.9 ORX87843.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ORX87843.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 ORX87843.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORX87843.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORX87843.1 - 0.025 14.3 0.0 0.078 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORX87843.1 - 0.025 14.3 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX87843.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 ORX87843.1 - 0.039 13.8 0.3 0.44 10.4 0.0 2.5 1 1 1 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 ORX87843.1 - 0.044 13.4 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 ORX87843.1 - 0.055 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 ORX87843.1 - 0.065 13.1 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 ORX87843.1 - 0.092 13.2 0.8 0.12 12.8 0.6 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORX87843.1 - 0.12 11.5 0.0 0.52 9.5 0.0 1.7 1 1 1 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 ORX87843.1 - 0.13 12.3 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T3SS_needle_E PF08988.10 ORX87843.1 - 0.17 12.0 0.3 0.29 11.3 0.3 1.3 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Chs7 PF12271.8 ORX87844.1 - 1.1e-100 336.8 19.4 1.2e-100 336.6 19.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone ATP1G1_PLM_MAT8 PF02038.16 ORX87844.1 - 1.6 8.3 5.1 0.45 10.0 0.6 2.4 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family DUF2070 PF09843.9 ORX87844.1 - 9.7 4.3 23.9 2.3 6.4 20.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Snf7 PF03357.21 ORX87845.1 - 6.9e-44 149.5 26.6 9.2e-44 149.1 26.6 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 ORX87845.1 - 0.044 13.7 7.7 0.065 13.2 7.7 1.4 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF677 PF05055.12 ORX87845.1 - 0.057 12.3 10.1 0.014 14.4 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) TPR_MLP1_2 PF07926.12 ORX87845.1 - 0.43 10.7 14.3 0.11 12.5 9.8 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 ORX87845.1 - 3 8.2 21.2 13 6.2 11.8 2.2 1 1 1 2 2 2 0 YlqD protein YEATS PF03366.16 ORX87846.1 - 1.2e-20 73.2 0.4 2.7e-20 72.1 0.4 1.6 1 0 0 1 1 1 1 YEATS family 2-oxoacid_dh PF00198.23 ORX87847.1 - 3.8e-79 265.4 1.0 5.1e-79 265.0 1.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORX87847.1 - 3.5e-17 62.0 1.8 6.7e-17 61.1 1.4 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme GCV_H PF01597.19 ORX87847.1 - 0.00011 22.1 0.6 0.00023 21.1 0.6 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 ORX87847.1 - 0.0014 19.3 0.1 0.13 13.0 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 ORX87847.1 - 0.01 15.8 0.1 0.027 14.4 0.1 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 ORX87847.1 - 0.098 12.5 0.1 0.94 9.4 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like CCDC53 PF10152.9 ORX87847.1 - 0.38 11.1 5.8 0.91 9.9 5.8 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PcfK PF14058.6 ORX87847.1 - 1.2 9.4 4.4 8.6 6.6 3.1 2.2 2 0 0 2 2 2 0 PcfK-like protein FAP PF07174.11 ORX87847.1 - 6.3 6.2 15.5 13 5.1 15.5 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Hexapep PF00132.24 ORX87848.1 - 1e-11 44.1 16.4 7.9e-11 41.2 6.5 3.7 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 ORX87848.1 - 3.7e-11 43.1 0.3 2e-10 40.7 0.1 2.0 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 ORX87848.1 - 1.4e-10 40.7 12.5 1.4e-09 37.5 5.3 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Acetyltransf_11 PF13720.6 ORX87848.1 - 0.048 14.1 0.2 0.085 13.3 0.2 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AMP-binding PF00501.28 ORX87850.1 - 3.2e-46 157.8 0.0 4.1e-45 154.2 0.0 2.0 1 1 1 2 2 2 1 AMP-binding enzyme Thioesterase PF00975.20 ORX87850.1 - 1.1e-30 107.4 0.0 2.2e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 ORX87850.1 - 0.00031 21.4 0.0 0.00096 19.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX87850.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PP-binding PF00550.25 ORX87850.1 - 0.0029 17.9 0.0 0.0094 16.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 ORX87850.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PE-PPE PF08237.11 ORX87850.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Ribosomal_L10 PF00466.20 ORX87935.1 - 1e-24 86.6 0.7 1.4e-24 86.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORX87935.1 - 1.6e-21 76.0 0.0 2.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P tRNA-synt_1 PF00133.22 ORX87936.1 - 7.5e-180 599.1 0.2 7.5e-179 595.8 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORX87936.1 - 1.5e-39 135.4 0.2 1.4e-38 132.2 0.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORX87936.1 - 3.3e-14 52.4 2.8 1e-05 24.5 0.0 4.6 3 2 2 5 5 5 3 tRNA synthetases class I (M) TPR_1 PF00515.28 ORX87936.1 - 3.6e-12 45.6 7.6 5.3e-05 22.9 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX87936.1 - 4.3e-11 42.0 5.2 0.00048 20.0 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX87936.1 - 1.6e-09 37.3 3.3 3e-05 23.6 0.1 3.6 3 0 0 3 3 3 2 TPR repeat Val_tRNA-synt_C PF10458.9 ORX87936.1 - 5.1e-07 29.9 2.0 1.3e-06 28.6 2.0 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 ORX87936.1 - 1.3e-06 28.0 0.0 2.5e-05 23.8 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 TPR_19 PF14559.6 ORX87936.1 - 1.3e-05 25.6 1.1 3e-05 24.5 0.3 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX87936.1 - 1.4e-05 25.3 0.7 0.00019 21.6 0.4 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORX87936.1 - 4.1e-05 24.1 0.1 1 10.3 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX87936.1 - 0.00011 22.1 5.1 0.71 10.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat tRNA-synt_1e PF01406.19 ORX87936.1 - 0.00013 21.4 0.0 0.005 16.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain TPR_9 PF13371.6 ORX87936.1 - 0.00015 21.9 1.5 0.013 15.6 1.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX87936.1 - 0.01 15.8 0.1 12 6.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORX87936.1 - 0.064 13.9 0.3 0.28 11.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Fungal_TACC PF12709.7 ORX87936.1 - 0.073 13.5 0.1 8.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_17 PF13431.6 ORX87936.1 - 0.08 13.4 0.6 16 6.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DivIC PF04977.15 ORX87936.1 - 0.1 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Septum formation initiator Matrilin_ccoil PF10393.9 ORX87936.1 - 0.15 12.0 0.2 0.43 10.5 0.2 1.9 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin COG2 PF06148.11 ORX87936.1 - 0.17 12.0 2.1 0.45 10.6 0.3 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC-167 PF15188.6 ORX87936.1 - 1.2 9.5 3.7 2.3 8.6 1.6 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 V-SNARE PF05008.15 ORX87936.1 - 3.4 8.1 6.7 0.47 10.9 0.6 2.7 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus Zip PF02535.22 ORX87938.1 - 0.78 8.9 7.8 0.99 8.6 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmodium_HRP PF05403.11 ORX87939.1 - 6.1e-10 39.3 45.0 0.00022 21.1 32.8 3.2 1 1 1 3 3 3 3 Plasmodium histidine-rich protein (HRPII/III) CBM_19 PF03427.13 ORX87939.1 - 0.0017 18.3 6.7 0.0078 16.2 6.7 2.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX87939.1 - 5.2 7.3 9.7 0.72 10.1 3.9 2.6 2 1 1 3 3 3 0 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 ORX87940.1 - 0.00011 22.1 11.6 0.00037 20.4 9.4 2.5 2 1 0 2 2 2 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX87940.1 - 0.042 14.0 3.4 0.24 11.6 3.7 2.1 1 1 1 2 2 2 0 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 ORX87941.1 - 5.2e-06 26.3 6.3 8.4e-06 25.7 6.3 1.4 1 1 0 1 1 1 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX87941.1 - 0.0092 16.1 3.9 0.11 12.7 4.5 2.0 1 1 1 2 2 2 2 Chitin binding Peritrophin-A domain CBM_1 PF00734.18 ORX87941.1 - 5.6 7.0 11.4 1.4 8.9 0.9 2.6 3 0 0 3 3 3 0 Fungal cellulose binding domain ACPS PF01648.20 ORX87943.1 - 7.7e-12 45.4 0.0 9.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Synaptobrevin PF00957.21 ORX87944.1 - 1.7e-20 72.6 2.0 1.9e-20 72.4 2.0 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.8 ORX87944.1 - 0.1 12.3 0.4 0.11 12.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) GDC-P PF02347.16 ORX87945.1 - 9.6e-206 683.7 3.9 2.4e-194 646.1 0.1 3.3 4 0 0 4 4 4 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ORX87945.1 - 6.9e-06 25.2 1.3 1.9e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORX87945.1 - 0.00011 21.6 0.6 0.0017 17.7 0.0 2.6 3 0 0 3 3 3 1 Beta-eliminating lyase DUF1805 PF08827.11 ORX87945.1 - 0.0079 16.5 0.0 0.061 13.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1805) SMC_N PF02463.19 ORX87946.1 - 6.2e-17 61.8 0.0 6.2e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX87946.1 - 2.9e-11 44.3 0.0 3.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORX87946.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORX87946.1 - 2.6e-08 34.0 0.0 3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORX87946.1 - 2.4e-07 30.8 0.0 2.5e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 ORX87946.1 - 4.4e-05 23.2 0.0 5.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORX87946.1 - 0.0038 17.8 0.0 0.0052 17.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 ORX87946.1 - 0.039 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2813 PF11398.8 ORX87946.1 - 0.045 13.0 0.0 0.045 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) GATA PF00320.27 ORX88039.1 - 2e-14 52.9 8.0 3.4e-14 52.2 8.0 1.4 1 0 0 1 1 1 1 GATA zinc finger CNDH2_C PF16858.5 ORX88039.1 - 0.053 13.4 2.6 0.064 13.1 2.6 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF5327 PF17261.2 ORX88039.1 - 0.26 12.1 3.3 3 8.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) AIF_C PF14721.6 ORX88039.1 - 2 8.8 5.3 22 5.4 2.0 2.2 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pkinase PF00069.25 ORX88040.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Bromodomain PF00439.25 ORX88041.1 - 1.1e-42 144.0 5.5 1.4e-21 76.4 1.5 3.4 2 1 1 3 3 3 2 Bromodomain BAH PF01426.18 ORX88041.1 - 1.2e-20 73.6 1.5 2.3e-20 72.6 1.5 1.5 1 0 0 1 1 1 1 BAH domain Ank_2 PF12796.7 ORX88041.1 - 3.1e-06 27.7 0.0 2.2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX88041.1 - 0.00018 21.8 0.0 0.16 12.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORX88041.1 - 0.00034 21.1 0.0 0.0062 17.1 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX88041.1 - 0.0079 16.5 0.0 1.3 9.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mpp10 PF04006.12 ORX88041.1 - 0.014 13.9 32.0 0.031 12.7 32.0 1.5 1 0 0 1 1 1 0 Mpp10 protein Ank_3 PF13606.6 ORX88041.1 - 0.048 14.2 0.0 28 5.7 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Lyase_1 PF00206.20 ORX88042.1 - 5.5e-21 75.3 0.0 8.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORX88042.1 - 1.3e-16 60.9 0.0 4.8e-16 59.1 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus L51_S25_CI-B8 PF05047.16 ORX88043.1 - 4.2e-12 45.8 0.1 7.3e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA PF00004.29 ORX88044.1 - 3.6e-43 147.2 0.0 8.5e-43 145.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORX88044.1 - 1.1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORX88044.1 - 3.9e-08 33.0 0.3 7.2e-08 32.1 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORX88044.1 - 5.7e-07 29.8 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORX88044.1 - 1.9e-06 28.2 0.1 0.0017 18.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORX88044.1 - 3e-05 24.0 0.1 0.00019 21.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ORX88044.1 - 5.7e-05 22.4 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORX88044.1 - 9.8e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORX88044.1 - 0.00043 20.7 0.1 0.0019 18.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 ORX88044.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 ORX88044.1 - 0.0033 17.7 0.2 0.0099 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX88044.1 - 0.0045 17.1 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORX88044.1 - 0.0046 16.3 0.2 0.24 10.7 0.0 2.8 2 1 0 3 3 3 1 KaiC RNA_helicase PF00910.22 ORX88044.1 - 0.0092 16.4 0.0 0.031 14.7 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 ORX88044.1 - 0.013 15.6 0.0 0.036 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 ORX88044.1 - 0.013 14.8 0.1 0.028 13.6 0.0 1.6 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 ORX88044.1 - 0.014 16.0 0.0 0.034 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORX88044.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORX88044.1 - 0.018 14.7 0.3 0.087 12.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORX88044.1 - 0.019 14.5 0.5 0.41 10.2 0.2 2.6 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 ORX88044.1 - 0.039 13.4 0.1 0.097 12.1 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 ORX88044.1 - 0.044 13.6 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX88044.1 - 0.045 13.7 0.0 0.62 10.0 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 ORX88044.1 - 0.07 12.8 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ORX88044.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Prot_ATP_OB_N PF17758.1 ORX88044.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 ORX88044.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 ORX88044.1 - 0.12 11.5 0.0 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 ORX88044.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 ORX88044.1 - 0.15 12.6 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 ORX88044.1 - 0.16 11.7 0.1 0.56 9.9 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain Glutaredoxin PF00462.24 ORX88045.1 - 1.3e-19 70.2 0.0 1.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 ORX88045.1 - 0.012 16.1 0.1 0.014 15.8 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 ORX88045.1 - 0.016 15.6 0.1 0.02 15.3 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 ORX88045.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 ORX88045.1 - 0.036 13.8 0.0 0.05 13.4 0.0 1.3 1 1 0 1 1 1 0 DSBA-like thioredoxin domain GST_N_3 PF13417.6 ORX88045.1 - 0.088 13.2 0.1 0.21 12.0 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF953 PF06110.11 ORX88045.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) PWWP PF00855.17 ORX88046.1 - 4.1e-22 78.4 0.5 1.4e-21 76.7 0.5 2.0 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 ORX88046.1 - 2.8e-05 24.0 0.1 7.5e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Bromodomain PF00439.25 ORX88047.1 - 9e-33 112.2 0.2 3e-13 49.6 0.0 3.1 2 1 1 3 3 3 3 Bromodomain Wzy_C_2 PF11846.8 ORX88048.1 - 0.037 14.0 0.2 0.037 14.0 0.2 2.4 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF2569 PF10754.9 ORX88048.1 - 1.4 9.4 9.4 0.2 12.1 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) PrgI PF12666.7 ORX88048.1 - 3 8.6 8.3 0.49 11.1 0.1 2.8 3 0 0 3 3 3 0 PrgI family protein DUF1648 PF07853.11 ORX88049.1 - 3.7e-05 23.3 0.1 3.7e-05 23.3 0.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1648) TssO PF17561.2 ORX88049.1 - 0.0054 16.9 1.4 0.0054 16.9 1.4 2.1 3 0 0 3 3 3 1 Type VI secretion system, TssO Peptidase_M48_N PF16491.5 ORX88049.1 - 0.14 12.1 13.6 0.076 12.9 2.5 2.1 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DHHC PF01529.20 ORX88049.1 - 2.3 8.4 9.6 4.8 7.3 1.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ras PF00071.22 ORX88050.1 - 2.2e-55 186.7 0.0 2.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX88050.1 - 1.3e-21 77.0 0.0 2.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX88050.1 - 3.2e-06 26.7 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX88050.1 - 0.0023 17.4 0.0 0.0037 16.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit adh_short PF00106.25 ORX88051.1 - 1.5e-82 275.8 13.1 4.8e-45 153.4 2.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX88051.1 - 3.1e-67 226.6 8.8 6.5e-39 133.9 0.5 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 ORX88051.1 - 2.8e-31 107.6 0.1 8.1e-31 106.1 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain KR PF08659.10 ORX88051.1 - 3.6e-31 108.5 7.7 1.9e-16 60.5 1.6 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 ORX88051.1 - 1.2e-07 31.9 0.0 1.2e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 ORX88051.1 - 0.0035 16.7 2.0 0.46 9.8 0.2 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 ORX88051.1 - 0.0085 15.5 0.5 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 ORX88051.1 - 0.062 12.8 3.8 4.4 6.8 0.1 2.6 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.21 ORX88051.1 - 0.081 12.4 1.9 1.7 8.0 0.2 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORX88051.1 - 1.4 8.8 7.8 2.4 8.0 0.9 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 ORX88051.1 - 1.7 8.7 4.1 15 5.6 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF543) PglL_A PF15864.5 ORX88051.1 - 4.8 7.0 8.3 10 6.0 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Ldh_1_N PF00056.23 ORX88051.1 - 6.7 6.8 8.7 1.2 9.3 0.8 2.7 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Kelch_4 PF13418.6 ORX88052.1 - 3.6e-17 62.1 6.8 0.00017 21.5 0.1 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.25 ORX88052.1 - 1.6e-16 59.6 3.8 8.3e-08 31.7 0.1 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 ORX88052.1 - 4.7e-16 58.4 3.2 2.6e-05 24.3 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 ORX88052.1 - 2.6e-14 52.8 1.9 1.7e-06 27.9 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 ORX88052.1 - 2.3e-13 50.0 7.4 5.7e-08 32.9 0.1 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORX88052.1 - 8.2e-11 41.4 4.4 0.0047 16.9 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Pox_A_type_inc PF04508.12 ORX88052.1 - 1.1 9.2 10.4 2.1 8.4 0.4 4.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat FYVE PF01363.21 ORX88054.1 - 7.3e-17 61.3 16.2 1.7e-16 60.1 16.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 ORX88054.1 - 3.9e-07 30.5 0.4 2.9e-06 27.7 0.0 2.6 3 0 0 3 3 3 1 PH domain Guanylate_cyc_2 PF09778.9 ORX88055.1 - 3.1e-63 213.0 0.1 3.5e-63 212.8 0.1 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 ORX88055.1 - 0.00018 22.0 0.0 0.34 11.5 0.0 2.3 2 1 0 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.8 ORX88055.1 - 0.0002 21.4 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 ORX88055.1 - 0.0043 16.9 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase C39 family Viral_NABP PF05515.11 ORX88055.1 - 0.053 13.4 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding TRM PF02005.16 ORX88056.1 - 2.7e-133 444.8 0.1 3.4e-133 444.5 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 ORX88056.1 - 4.7e-06 26.5 0.0 8.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 ORX88056.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 ORX88056.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Pox_D5 PF03288.16 ORX88056.1 - 0.15 12.5 1.1 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 Poxvirus D5 protein-like Amj PF10997.8 ORX88056.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Alternate to MurJ Raptor_N PF14538.6 ORX88057.1 - 1.6e-68 229.3 0.0 3.4e-68 228.2 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 ORX88057.1 - 5.9e-11 41.7 1.4 0.0016 18.5 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat WD40 PF00400.32 ORX88057.1 - 8.1e-11 42.3 14.7 0.056 14.3 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat HEAT_2 PF13646.6 ORX88057.1 - 6.9e-08 32.8 0.1 3.8e-05 24.0 0.0 3.5 3 1 1 4 4 4 2 HEAT repeats ANAPC4_WD40 PF12894.7 ORX88057.1 - 0.0001 22.5 0.1 3.9 7.8 0.1 4.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 ORX88057.1 - 0.00019 21.5 0.0 0.12 12.5 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORX88057.1 - 0.0024 18.3 0.4 0.8 10.3 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORX88057.1 - 0.11 13.2 0.0 1.6 9.3 0.0 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Myb_DNA-bind_7 PF15963.5 ORX88058.1 - 9.5e-25 86.3 0.3 1.7e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORX88058.1 - 7.3e-11 42.1 0.1 1.4e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX88058.1 - 1.6e-05 25.1 0.1 2.7e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain TMEM164 PF14808.6 ORX88059.1 - 2.9e-25 89.1 12.8 3.8e-25 88.7 12.8 1.1 1 0 0 1 1 1 1 TMEM164 family HLH PF00010.26 ORX88143.1 - 1.9e-13 50.1 0.8 3.6e-13 49.2 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PDZ_5 PF17817.1 ORX88145.1 - 0.014 15.7 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 PDZ domain Acetate_kinase PF00871.17 ORX88146.1 - 1.2e-116 389.7 0.6 1.7e-116 389.2 0.6 1.2 1 0 0 1 1 1 1 Acetokinase family CAP PF00188.26 ORX88148.1 - 7.1e-14 52.7 0.2 9.5e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX88149.1 - 0.071 14.0 0.0 0.49 11.3 0.0 2.0 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 ORX88150.1 - 7.1e-14 52.7 0.2 9.5e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX88151.1 - 0.001 19.9 0.3 0.0056 17.5 0.3 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX88152.1 - 1.1e-12 48.9 0.2 1.4e-12 48.6 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WW PF00397.26 ORX88153.1 - 2.7e-14 52.9 1.3 8.9e-14 51.3 1.3 2.0 1 0 0 1 1 1 1 WW domain Rick_17kDa_Anti PF05433.15 ORX88153.1 - 0.16 11.9 8.6 0.31 10.9 0.2 2.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain CAP PF00188.26 ORX88154.1 - 7.3e-05 23.6 0.0 0.00019 22.3 0.0 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family zf-C2H2 PF00096.26 ORX88155.1 - 8.2e-12 44.9 11.5 2.7e-07 30.7 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX88155.1 - 8.2e-08 32.5 8.9 0.00012 22.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX88155.1 - 4.8e-06 26.8 1.6 4.8e-06 26.8 1.6 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX88155.1 - 9.1e-05 22.4 0.3 9.1e-05 22.4 0.3 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORX88155.1 - 0.00012 22.6 3.6 0.0081 16.8 0.3 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain Ogr_Delta PF04606.12 ORX88155.1 - 0.0075 16.2 0.2 0.65 10.0 0.0 2.2 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zf-C2H2_aberr PF17017.5 ORX88155.1 - 0.0098 16.1 2.6 1.9 8.6 0.3 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORX88155.1 - 0.018 15.3 0.3 0.046 14.0 0.3 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 ORX88155.1 - 0.053 13.3 0.5 0.053 13.3 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 ORX88155.1 - 0.32 11.4 3.3 2.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Nucleos_tra2_C PF07662.13 ORX88156.1 - 8.1e-75 251.2 7.1 8.1e-75 251.2 7.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX88156.1 - 9.2e-24 83.8 3.4 9.2e-24 83.8 3.4 4.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX88156.1 - 0.0046 17.2 8.6 0.0046 17.2 8.6 4.3 3 2 0 3 3 3 1 Nucleoside recognition Protoglobin PF11563.8 ORX88157.1 - 1.2e-37 129.3 0.6 1.4e-37 129.0 0.6 1.0 1 0 0 1 1 1 1 Protoglobin PX PF00787.24 ORX88157.1 - 0.13 12.3 0.1 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 PX domain Nucleos_tra2_C PF07662.13 ORX88158.1 - 8.1e-75 251.2 7.1 8.1e-75 251.2 7.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX88158.1 - 9.2e-24 83.8 3.4 9.2e-24 83.8 3.4 4.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX88158.1 - 0.0046 17.2 8.6 0.0046 17.2 8.6 4.3 3 2 0 3 3 3 1 Nucleoside recognition Protoglobin PF11563.8 ORX88159.1 - 3.3e-37 127.8 0.6 4e-37 127.6 0.6 1.0 1 0 0 1 1 1 1 Protoglobin tRNA-synt_1e PF01406.19 ORX88159.1 - 0.12 11.8 0.7 0.14 11.5 0.7 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PX PF00787.24 ORX88159.1 - 0.13 12.3 0.2 0.56 10.2 0.0 2.1 3 0 0 3 3 3 0 PX domain Protoglobin PF11563.8 ORX88160.1 - 6.8e-37 126.8 0.5 7.9e-37 126.6 0.5 1.0 1 0 0 1 1 1 1 Protoglobin TetR_C_23 PF17931.1 ORX88160.1 - 0.0088 16.2 0.1 4.8 7.3 0.1 2.3 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain SH3_1 PF00018.28 ORX88162.1 - 6.1e-11 41.8 0.0 8.9e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX88162.1 - 5e-09 35.7 0.0 7.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORX88162.1 - 3.3e-07 30.0 0.0 5.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PepSY_TM PF03929.16 ORX88162.1 - 0.022 14.5 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region SH3_3 PF08239.11 ORX88162.1 - 0.047 14.0 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Toxin_22 PF08092.11 ORX88162.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Magi peptide toxin family Glucosamine_iso PF01182.20 ORX88163.1 - 4.8e-78 262.1 0.0 5.4e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase OHCU_decarbox PF09349.10 ORX88164.1 - 1.3e-37 129.7 0.0 1.5e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase EF-hand_1 PF00036.32 ORX88165.1 - 3.6e-30 101.2 13.4 8.8e-07 28.0 1.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX88165.1 - 3.1e-29 101.2 8.5 1.2e-15 57.7 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX88165.1 - 3.8e-27 93.9 14.8 2.1e-12 46.7 0.2 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ORX88165.1 - 4.4e-23 79.2 15.5 4e-07 29.4 0.6 4.9 3 1 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 ORX88165.1 - 2.4e-21 74.2 13.4 3.7e-06 26.2 0.2 4.2 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 ORX88165.1 - 4.8e-09 36.5 2.3 0.00036 20.8 0.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORX88165.1 - 1e-08 35.3 0.4 0.00035 20.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORX88165.1 - 0.00016 21.6 6.3 0.17 11.8 0.3 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 ORX88165.1 - 0.00061 19.8 0.0 0.065 13.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 ORX88165.1 - 0.0029 17.8 0.4 0.48 10.7 0.0 2.4 2 0 0 2 2 2 1 Dockerin type I domain DUF5580 PF17743.1 ORX88165.1 - 0.034 12.7 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Caleosin PF05042.13 ORX88165.1 - 0.4 10.6 2.6 7.1 6.5 0.1 3.0 1 1 2 3 3 3 0 Caleosin related protein EF-hand_10 PF14788.6 ORX88165.1 - 2 8.4 6.0 2.3 8.1 0.4 2.9 3 0 0 3 3 3 0 EF hand LIDHydrolase PF10230.9 ORX88166.1 - 1.3e-63 215.0 0.0 1.5e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORX88166.1 - 2.1e-05 23.9 0.0 2.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX88166.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX88166.1 - 0.013 16.1 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX88166.1 - 0.067 12.9 0.1 0.16 11.6 0.0 1.7 2 1 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORX88166.1 - 0.1 12.4 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 ORX88166.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.8 ORX88166.1 - 0.12 11.5 0.0 0.43 9.7 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2920) Aph-1 PF06105.12 ORX88167.1 - 2.6e-30 105.5 8.0 3.1e-30 105.3 8.0 1.0 1 0 0 1 1 1 1 Aph-1 protein SAYSvFN PF10260.9 ORX88167.1 - 2.7 8.0 7.6 4.5 7.3 1.7 2.8 1 1 1 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) FH2 PF02181.23 ORX88169.1 - 1e-93 314.4 11.0 1e-93 314.4 11.0 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORX88169.1 - 1.3e-38 132.6 0.7 1.3e-38 132.6 0.7 3.2 4 0 0 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 ORX88169.1 - 4.1e-22 78.7 10.8 1.2e-16 60.8 2.6 3.3 2 1 1 3 3 3 2 Diaphanous GTPase-binding Domain Drf_DAD PF06345.11 ORX88169.1 - 0.007 16.3 0.0 0.04 14.0 0.0 2.4 1 0 0 1 1 1 1 DRF Autoregulatory Domain Rotamase_2 PF13145.6 ORX88169.1 - 0.67 10.8 0.0 0.67 10.8 0.0 3.8 4 0 0 4 4 4 0 PPIC-type PPIASE domain DUF2564 PF10819.8 ORX88169.1 - 4.5 7.7 6.5 2 8.9 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) DUF4407 PF14362.6 ORX88169.1 - 9.7 5.4 10.2 3.5 6.9 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-Tim10_DDP PF02953.15 ORX88170.1 - 6.7e-19 67.3 2.4 9.9e-19 66.8 2.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4787 PF16029.5 ORX88170.1 - 0.012 15.7 0.9 0.02 15.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) Ins_beta PF03488.14 ORX88170.1 - 0.025 14.6 1.1 0.039 14.0 1.1 1.2 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Vicilin_N PF04702.12 ORX88170.1 - 0.089 12.6 4.3 0.1 12.5 4.3 1.1 1 0 0 1 1 1 0 Vicilin N terminal region DUF445 PF04286.12 ORX88170.1 - 0.092 12.5 0.2 0.09 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) LIP PF03583.14 ORX88170.1 - 0.17 11.1 0.2 0.18 11.1 0.2 1.1 1 0 0 1 1 1 0 Secretory lipase TP_methylase PF00590.20 ORX88171.1 - 3e-41 141.7 0.1 4.2e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORX88171.1 - 6.4e-31 106.9 0.0 1.5e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORX88171.1 - 2.4e-23 81.5 0.0 6.3e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORX88171.1 - 3.1e-14 52.1 0.2 7.2e-14 50.9 0.2 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 ORX88171.1 - 0.00023 20.5 0.0 0.00047 19.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORX88171.1 - 0.16 11.3 0.1 0.7 9.1 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_34 PF05637.12 ORX88173.1 - 5.4e-48 163.8 0.6 1.4e-45 155.9 0.6 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORX88173.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF273 HydF_tetramer PF18133.1 ORX88173.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain MRP-L27 PF09809.9 ORX88174.1 - 1.4e-10 41.0 0.1 1.6e-10 40.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Tmemb_170 PF10190.9 ORX88175.1 - 1.1e-16 61.0 12.6 1.3e-16 60.8 12.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Phage_holin_2_3 PF16080.5 ORX88175.1 - 0.093 12.5 1.0 0.093 12.5 1.0 2.6 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Ecl1 PF12855.7 ORX88176.1 - 1.6e-10 42.5 3.3 1.8e-10 42.2 3.3 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 ORX88176.1 - 0.59 9.7 3.8 12 5.4 3.8 2.3 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DNA_ligase_A_M PF01068.21 ORX88177.1 - 5.2e-55 186.3 0.0 2.7e-54 183.9 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORX88177.1 - 2.7e-29 102.7 0.0 7.2e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 ORX88177.1 - 5.5e-19 68.4 0.3 1.5e-11 44.5 0.0 3.6 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 ORX88177.1 - 7.4e-17 61.8 0.0 2.1e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORX88177.1 - 5.9e-10 39.7 0.0 1.4e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 ORX88177.1 - 3e-07 30.7 0.4 0.014 15.8 0.0 3.3 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 ORX88177.1 - 6.3e-07 29.4 0.1 1.3e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 ORX88177.1 - 1.3e-05 25.4 0.4 0.21 11.9 0.1 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain mRNA_cap_enzyme PF01331.19 ORX88177.1 - 0.00028 20.8 0.3 0.0029 17.5 0.0 2.8 3 1 0 3 3 3 1 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.7 ORX88177.1 - 0.0067 16.4 0.1 0.55 10.2 0.0 2.7 2 0 0 2 2 2 1 twin BRCT domain Acyl-CoA_dh_1 PF00441.24 ORX88178.1 - 1.5e-43 148.6 1.2 2.1e-43 148.1 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORX88178.1 - 3.5e-28 98.5 0.0 9.9e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORX88178.1 - 7.5e-21 74.1 0.0 1.3e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORX88178.1 - 8.9e-20 71.3 0.0 1.4e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 ORX88178.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein Pyridoxal_deC PF00282.19 ORX88179.1 - 9.4e-87 291.2 0.0 1.2e-86 290.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ORX88179.1 - 6.2e-06 25.7 0.0 8.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORX88179.1 - 6.2e-06 25.4 0.0 3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V PAPS_reduct PF01507.19 ORX88180.1 - 1.5e-31 109.8 0.0 2.1e-20 73.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family GATA PF00320.27 ORX88181.1 - 2.6e-28 97.3 17.0 1.2e-14 53.6 5.7 2.4 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORX88181.1 - 6.1e-12 45.2 3.1 1.8e-11 43.7 3.1 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 ORX88181.1 - 1.6e-06 27.5 5.3 0.0047 16.4 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX88181.1 - 0.00052 20.1 0.6 0.76 9.9 0.0 2.6 2 0 0 2 2 2 2 Zinc ribbon domain DZR PF12773.7 ORX88181.1 - 0.029 14.4 4.7 0.73 9.9 4.9 2.9 1 1 1 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.12 ORX88181.1 - 0.036 14.2 5.6 2.5 8.3 0.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OTT_1508_deam PF14441.6 ORX88181.1 - 0.34 10.9 2.4 28 4.8 0.0 3.3 3 0 0 3 3 3 0 OTT_1508-like deaminase eIF-5_eIF-2B PF01873.17 ORX88181.1 - 1.1 9.1 5.7 5.3 6.9 0.5 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 FAM163 PF15069.6 ORX88181.1 - 1.3 9.4 6.2 1 9.8 0.4 2.9 2 1 1 3 3 3 0 FAM163 family zf-RRPl_C4 PF17026.5 ORX88181.1 - 2.6 8.2 7.2 0.96 9.6 0.7 2.8 2 1 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Tnp_zf-ribbon_2 PF13842.6 ORX88181.1 - 2.8 8.8 4.8 1.2e+02 3.6 0.3 3.7 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon OrfB_Zn_ribbon PF07282.11 ORX88181.1 - 3.4 7.7 7.5 2.7 8.0 0.4 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Vps36-NZF-N PF16988.5 ORX88181.1 - 6 6.3 11.2 9.4 5.7 0.3 4.2 2 2 2 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_15 PF17032.5 ORX88181.1 - 7.2 7.4 6.1 41 5.0 3.3 2.9 1 1 2 3 3 3 0 zinc-ribbon family A2L_zn_ribbon PF08792.10 ORX88181.1 - 7.8 6.3 9.4 2.5 7.9 0.2 3.5 4 0 0 4 4 4 0 A2L zinc ribbon domain RF-1 PF00472.20 ORX88182.1 - 3.7e-23 81.7 3.2 6.4e-23 80.9 3.2 1.3 1 0 0 1 1 1 1 RF-1 domain DUF2407_C PF13373.6 ORX88182.1 - 1.1 9.4 3.5 0.51 10.5 0.6 1.8 1 1 0 2 2 2 0 DUF2407 C-terminal domain Band_7 PF01145.25 ORX88314.1 - 4.7e-28 98.4 1.1 7.2e-28 97.8 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX88314.1 - 0.011 15.5 0.1 0.019 14.6 0.1 1.4 1 1 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORX88314.1 - 0.053 13.1 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 UBD PF16455.5 ORX88316.1 - 2.9e-31 107.8 0.0 4.2e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 ORX88316.1 - 2.2e-09 36.9 0.0 7.4e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ORX88316.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SUIM_assoc PF16619.5 ORX88316.1 - 0.068 13.2 0.0 0.47 10.6 0.0 2.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Rad60-SLD_2 PF13881.6 ORX88316.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORX88316.1 - 0.14 12.7 0.0 0.63 10.6 0.0 1.9 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain CLTH PF10607.9 ORX88317.1 - 6.4e-31 107.2 0.5 1.3e-30 106.3 0.1 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ORX88317.1 - 2.4e-10 40.3 1.2 4.7e-10 39.3 1.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX88317.1 - 4.6e-07 29.7 1.6 8e-07 28.9 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORX88317.1 - 2.9e-05 24.3 1.8 5.7e-05 23.4 1.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORX88317.1 - 4.8e-05 23.1 1.6 9.7e-05 22.2 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORX88317.1 - 6.3e-05 22.8 1.4 0.00011 21.9 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX88317.1 - 0.00025 20.8 3.3 0.00049 19.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Bacillus_HBL PF05791.11 ORX88317.1 - 0.0007 19.5 2.5 0.0015 18.4 2.5 1.5 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) zf-C3HC4_4 PF15227.6 ORX88317.1 - 0.00093 19.3 2.7 0.0022 18.1 2.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORX88317.1 - 0.0013 18.6 3.1 0.0027 17.5 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Apolipoprotein PF01442.18 ORX88317.1 - 0.0043 16.9 0.2 0.0069 16.3 0.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Hemagglutinin PF00509.18 ORX88317.1 - 0.019 13.4 0.7 0.035 12.5 0.7 1.3 1 1 0 1 1 1 0 Haemagglutinin DUF2408 PF10303.9 ORX88317.1 - 0.029 14.9 0.9 0.059 13.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) zf-C2HC5 PF06221.13 ORX88317.1 - 0.029 14.3 0.3 0.077 13.0 0.3 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type LmjF365940-deam PF14421.6 ORX88317.1 - 0.06 12.9 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases GLE1 PF07817.13 ORX88317.1 - 0.06 12.5 2.8 0.079 12.2 1.4 1.8 1 1 1 2 2 2 0 GLE1-like protein Baculo_PEP_C PF04513.12 ORX88317.1 - 0.1 12.7 0.3 0.2 11.7 0.2 1.5 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_4 PF14570.6 ORX88317.1 - 0.13 12.1 2.0 0.24 11.2 2.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF148 PF02520.17 ORX88317.1 - 0.14 12.3 3.5 0.5 10.5 3.3 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF148 SPX PF03105.19 ORX88317.1 - 0.39 10.6 5.9 0.51 10.2 5.9 1.1 1 0 0 1 1 1 0 SPX domain Fusion_gly PF00523.18 ORX88317.1 - 0.43 8.8 1.7 0.65 8.2 1.7 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 PhaP_Bmeg PF09602.10 ORX88317.1 - 0.5 10.3 6.4 0.85 9.5 6.4 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) zf-Nse PF11789.8 ORX88317.1 - 0.64 9.9 2.8 1.5 8.7 2.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PMM PF03332.13 ORX88318.1 - 3.4e-106 354.0 0.2 3.9e-106 353.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 ORX88318.1 - 4.3e-05 23.4 0.0 0.00036 20.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX88318.1 - 0.064 13.7 0.1 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORX88318.1 - 0.068 12.7 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORX88318.1 - 0.19 12.0 0.1 0.55 10.5 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase COX5A PF02284.16 ORX88319.1 - 3.2e-41 139.5 0.4 4.2e-41 139.1 0.1 1.3 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va DUF2357 PF09823.9 ORX88319.1 - 0.028 13.7 0.5 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) Peroxin-3 PF04882.12 ORX88320.1 - 2.1e-118 396.3 1.9 1.8e-81 274.6 0.2 2.0 1 1 1 2 2 2 2 Peroxin-3 Peptidase_M13_N PF05649.13 ORX88320.1 - 0.098 12.3 0.2 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 Peptidase family M13 Mon1 PF03164.14 ORX88321.1 - 4.5e-150 500.2 1.6 5.4e-150 500.0 1.6 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 GFD1 PF17331.2 ORX88321.1 - 6.2 7.1 6.9 1.6 9.0 0.1 2.7 3 0 0 3 3 3 0 GFD1 mRNA transport factor Bax1-I PF01027.20 ORX88322.1 - 4.8e-50 170.3 29.2 5.4e-50 170.1 29.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_P21 PF05313.12 ORX88322.1 - 0.063 12.8 6.4 0.088 12.4 6.4 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF1011 PF06237.12 ORX88322.1 - 0.27 11.6 9.7 0.95 9.8 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1011) DUF2070 PF09843.9 ORX88322.1 - 0.44 8.8 19.9 0.51 8.6 19.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Trypsin PF00089.26 ORX88323.1 - 2.2e-39 135.6 0.0 2.5e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX88323.1 - 0.00019 22.4 0.2 0.00037 21.4 0.2 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain GATA PF00320.27 ORX88324.1 - 1.8e-12 46.6 6.3 3.6e-12 45.7 6.3 1.6 1 0 0 1 1 1 1 GATA zinc finger O-FucT PF10250.9 ORX88325.1 - 1.5e-09 38.0 0.0 1e-07 32.0 0.0 2.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase FerA PF08165.11 ORX88326.1 - 0.015 15.2 0.2 0.67 9.9 0.0 2.8 2 0 0 2 2 2 0 FerA (NUC095) domain DUF2192 PF09958.9 ORX88326.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) LRR_8 PF13855.6 ORX88326.1 - 0.49 10.2 14.5 2.7 7.8 0.4 5.8 6 1 2 8 8 8 0 Leucine rich repeat Oxidored_molyb PF00174.19 ORX88329.1 - 7.9e-46 155.8 0.0 1.2e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 ORX88329.1 - 1.7e-32 111.7 0.0 1.4e-31 108.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORX88329.1 - 1.1e-29 103.3 0.0 2.7e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Mo-co_dimer PF03404.16 ORX88329.1 - 4.5e-22 78.6 0.0 9.1e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 ORX88329.1 - 1.3e-19 70.1 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORX88329.1 - 7.5e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain BNR PF02012.20 ORX88329.1 - 0.11 12.5 0.3 0.36 11.0 0.3 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Cyclin_N PF00134.23 ORX88330.1 - 1.7e-22 79.5 0.7 1.2e-17 63.8 0.3 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX88330.1 - 1.1e-05 25.5 0.2 0.00088 19.3 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 ORX88330.1 - 0.00054 20.0 0.3 0.25 11.4 0.1 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 ORX88330.1 - 0.0018 18.6 0.0 0.0051 17.2 0.0 1.8 1 0 0 1 1 1 1 Cyclin C-terminal domain TB2_DP1_HVA22 PF03134.19 ORX88331.1 - 7.4e-33 112.3 6.4 7.4e-33 112.3 6.4 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family OAD_gamma PF04277.13 ORX88331.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DOT1 PF08123.13 ORX88332.1 - 2.4e-71 239.5 0.1 5e-71 238.5 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 ORX88332.1 - 0.00021 21.2 0.0 0.00061 19.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX88332.1 - 0.00071 20.2 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX88332.1 - 0.0017 18.2 0.0 0.0044 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX88332.1 - 0.006 17.2 0.0 0.017 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX88332.1 - 0.0069 17.1 0.0 0.052 14.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ORX88332.1 - 0.038 13.3 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORX88332.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain tRNA-synt_1b PF00579.25 ORX88333.1 - 7.9e-71 238.8 0.0 1.1e-70 238.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2428 PF10350.9 ORX88334.1 - 2.8e-70 236.7 0.0 8.1e-70 235.2 0.0 1.9 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 ORX88334.1 - 8.8e-06 25.6 5.2 0.15 12.4 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 ORX88334.1 - 0.0039 17.5 2.1 12 6.3 0.0 4.9 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 ORX88334.1 - 0.6 10.7 2.7 39 4.9 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat NPV_P10 PF05531.12 ORX88334.1 - 0.92 10.0 7.0 2.4 8.7 0.2 4.4 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein TRM13 PF05206.14 ORX88335.1 - 5.5e-90 301.4 0.0 7.2e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 ORX88335.1 - 1.3e-10 40.8 6.2 4.4e-10 39.1 6.2 2.0 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 ORX88335.1 - 4.9e-10 39.1 0.9 4.9e-10 39.1 0.9 2.5 3 0 0 3 3 3 1 U11-48K-like CHHC zinc finger DUF2791 PF10923.8 ORX88335.1 - 0.033 13.0 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Rnk_N PF14760.6 ORX88335.1 - 0.15 12.6 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 Rnk N-terminus GSIII_N PF12437.8 ORX88338.1 - 1.5e-63 213.2 0.0 2.9e-63 212.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORX88338.1 - 2.1e-36 124.4 0.4 4.7e-36 123.2 0.4 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORX88338.1 - 2.6e-22 79.3 0.0 7.2e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain C2 PF00168.30 ORX88339.1 - 3e-16 59.6 0.0 4.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain Glyco_hydro_46 PF01374.18 ORX88340.1 - 3.8e-36 124.7 0.0 5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 LPMO_10 PF03067.15 ORX88341.1 - 0.00017 22.3 0.0 0.00035 21.3 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX88341.1 - 0.001 19.1 0.1 0.022 14.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 FliJ PF02050.16 ORX88343.1 - 0.011 16.0 3.1 0.014 15.7 3.1 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Stathmin PF00836.19 ORX88343.1 - 0.02 14.9 0.3 0.031 14.3 0.3 1.3 1 0 0 1 1 1 0 Stathmin family RecX PF02631.16 ORX88343.1 - 0.032 14.7 0.3 0.048 14.1 0.3 1.3 1 0 0 1 1 1 0 RecX family Uds1 PF15456.6 ORX88343.1 - 0.06 13.5 1.3 0.078 13.2 0.5 1.6 1 1 1 2 2 2 0 Up-regulated During Septation Trimer_CC PF08954.11 ORX88343.1 - 1 9.0 10.4 1.1 8.9 1.2 2.7 3 0 0 3 3 3 0 Trimerisation motif DAGAT PF03982.13 ORX88345.1 - 3.9e-104 347.7 0.0 4.5e-104 347.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Mito_carr PF00153.27 ORX88346.1 - 6.3e-60 199.1 5.3 1.6e-23 82.4 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 ORX88347.1 - 9.9e-50 166.4 5.3 8.3e-19 67.3 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX88347.1 - 0.15 11.2 0.6 4.6 6.3 0.2 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Peptidase_C48 PF02902.19 ORX88349.1 - 9.3e-38 130.2 0.2 1.3e-37 129.8 0.2 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BCL_N PF04714.13 ORX88349.1 - 0.2 11.7 1.1 0.92 9.6 0.5 2.2 2 0 0 2 2 2 0 BCL7, N-terminal conserver region SNF2_N PF00176.23 ORX88350.1 - 4.4e-42 144.1 2.6 7.7e-42 143.3 2.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORX88350.1 - 3.6e-08 33.6 0.1 8.9e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORX88350.1 - 0.1 12.3 3.1 0.74 9.4 0.2 3.0 2 1 0 2 2 2 0 SWI2/SNF2 ATPase APC_u15 PF16636.5 ORX88350.1 - 1 9.8 4.0 2.8 8.4 0.2 3.3 2 1 1 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF148 PF02520.17 ORX88350.1 - 2.7 8.2 8.3 0.7 10.0 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 Fasciclin PF02469.22 ORX88351.1 - 1.1e-42 145.2 0.0 1.8e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain ORMDL PF04061.14 ORX88352.1 - 1.9e-53 179.9 3.7 2.3e-53 179.7 3.7 1.1 1 0 0 1 1 1 1 ORMDL family PAS_3 PF08447.12 ORX88353.1 - 9e-07 29.1 0.1 5.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 ORX88353.1 - 0.00024 21.1 10.0 0.00053 20.0 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORX88353.1 - 0.00068 19.6 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 ORX88353.1 - 0.022 14.9 0.1 0.055 13.6 0.1 1.7 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 ORX88353.1 - 0.15 12.3 0.0 0.88 9.9 0.0 2.1 1 1 0 1 1 1 0 PAS domain HMG_box PF00505.19 ORX88354.1 - 3.6e-07 30.5 0.5 1.7e-06 28.4 0.4 2.1 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX88354.1 - 0.001 19.6 0.1 0.0054 17.3 0.0 2.2 1 1 1 2 2 2 1 HMG-box domain PRR20 PF15708.5 ORX88354.1 - 0.035 14.0 2.2 0.06 13.2 2.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 ORC6 PF05460.13 ORX88354.1 - 6.4 6.0 14.0 0.49 9.6 7.0 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) PAF-AH_p_II PF03403.13 ORX88355.1 - 1.3e-70 237.8 0.0 4.2e-70 236.2 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX88355.1 - 4.8e-12 45.3 0.0 1.2e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORX88355.1 - 7.4e-06 25.2 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 ORX88355.1 - 6.3e-05 22.4 0.0 0.056 12.7 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 ORX88355.1 - 0.004 16.7 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORX88355.1 - 0.0048 16.6 0.0 0.015 14.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX88355.1 - 0.01 16.4 0.0 0.046 14.3 0.0 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX88355.1 - 0.018 14.5 0.0 0.064 12.7 0.0 1.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX88355.1 - 0.055 13.3 0.1 0.28 11.0 0.1 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase zf-C2H2 PF00096.26 ORX88357.1 - 1.6e-18 66.0 19.9 2.3e-05 24.6 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX88357.1 - 1.7e-13 50.3 25.0 8.4e-06 26.0 2.1 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX88357.1 - 4.2e-08 33.4 19.3 0.024 15.4 0.3 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX88357.1 - 7.9e-05 22.9 4.5 0.051 13.9 1.1 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORX88357.1 - 0.0024 18.2 2.8 19 5.8 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORX88357.1 - 0.0093 16.6 5.3 0.74 10.5 0.2 3.4 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORX88357.1 - 0.035 14.2 10.0 3.3 7.8 0.3 3.4 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 ORX88357.1 - 0.71 10.0 18.4 0.79 9.8 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger CHORD PF04968.12 ORX88357.1 - 5 7.9 13.0 16 6.3 1.0 3.5 2 1 1 3 3 3 0 CHORD RRM_1 PF00076.22 ORX88358.1 - 1.5e-16 60.0 0.0 2.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF_4EBP PF05456.11 ORX88359.1 - 1.7e-31 108.5 7.2 2.7e-31 107.9 7.2 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HMG_box PF00505.19 ORX88360.1 - 1.7e-15 57.1 0.3 1.7e-15 57.1 0.3 1.9 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX88360.1 - 7.5e-06 26.5 0.2 7.5e-06 26.5 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain SIN1 PF05422.12 ORX88361.1 - 0.029 14.9 1.6 0.04 14.5 1.6 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) CSN5_C PF18323.1 ORX88361.1 - 0.043 14.7 0.6 0.057 14.3 0.6 1.2 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DIE2_ALG10 PF04922.12 ORX88362.1 - 2.1e-125 419.1 18.6 2.8e-125 418.7 18.6 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Clat_adaptor_s PF01217.20 ORX88363.1 - 6.4e-54 181.8 5.5 8.4e-54 181.4 5.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 7tm_1 PF00001.21 ORX88364.1 - 6.7 6.0 16.7 6.8 5.9 15.9 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RCC1 PF00415.18 ORX88365.1 - 1.6e-28 99.1 8.9 1.1e-07 32.4 0.0 7.0 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORX88365.1 - 1.2e-25 88.6 14.2 8.7e-06 25.4 0.1 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 ORX88365.1 - 5.4e-12 45.4 0.6 1.8e-11 43.8 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX88365.1 - 6.6e-09 35.4 0.4 1.5e-08 34.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORX88365.1 - 0.031 14.1 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 F-box Elongin_A PF06881.11 ORX88365.1 - 0.055 14.0 0.0 0.094 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RhoGEF PF00621.20 ORX88366.1 - 6e-50 170.0 6.0 1.7e-49 168.5 6.0 1.9 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 ORX88366.1 - 6.7e-29 99.3 1.1 1.4e-14 53.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORX88366.1 - 4e-27 93.8 1.0 1.7e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 ORX88366.1 - 2e-26 92.7 0.0 6.8e-26 90.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 ORX88366.1 - 8.7e-19 67.7 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH3_2 PF07653.17 ORX88366.1 - 1.3e-15 56.8 0.0 1.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 ORX88366.1 - 1.1e-09 38.2 0.0 4.1e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 ORX88366.1 - 0.0012 18.6 0.3 0.26 11.3 0.0 3.4 3 0 0 3 3 2 1 EF-hand domain EF-hand_1 PF00036.32 ORX88366.1 - 0.0021 17.5 0.0 0.0073 15.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORX88366.1 - 0.0022 18.4 0.0 0.012 16.1 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain pair PH_5 PF15405.6 ORX88366.1 - 0.0036 17.4 0.0 0.014 15.5 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORX88366.1 - 0.023 15.2 0.0 0.063 13.8 0.0 1.8 1 0 0 1 1 1 0 PH domain IQ_SEC7_PH PF16453.5 ORX88366.1 - 0.064 13.2 0.0 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 PH domain FlgT_N PF16548.5 ORX88366.1 - 0.11 13.1 0.9 0.54 10.9 0.9 2.2 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain DUF3573 PF12097.8 ORX88366.1 - 1.6 7.5 3.3 0.9 8.3 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF4407 PF14362.6 ORX88366.1 - 2.1 7.6 7.2 0.6 9.4 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.6 ORX88366.1 - 5.5 7.1 12.7 27 4.8 12.7 2.2 1 0 0 1 1 1 0 FlxA-like protein Asp PF00026.23 ORX88367.1 - 5.2e-66 223.2 0.0 6e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX88367.1 - 5.3e-16 59.4 0.0 5.7e-09 36.5 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORX88367.1 - 0.00057 20.5 0.0 2.1 9.0 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 ORX88367.1 - 0.089 13.4 0.1 24 5.6 0.0 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.23 ORX88370.1 - 8.2e-63 212.6 19.3 8.4e-35 120.7 4.6 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX88370.1 - 2.5e-55 186.7 0.0 2e-32 112.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX88370.1 - 1e-08 34.9 3.8 9.1e-05 22.0 0.1 4.2 4 1 1 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX88370.1 - 2.8e-05 24.7 0.1 0.35 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORX88370.1 - 6.1e-05 22.7 0.5 0.52 10.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORX88370.1 - 7.4e-05 22.7 0.1 0.031 14.2 0.1 2.7 2 1 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ORX88370.1 - 0.00026 20.6 0.0 0.85 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORX88370.1 - 0.0011 19.0 0.4 0.29 11.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX88370.1 - 0.0015 19.0 0.2 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX88370.1 - 0.0033 17.7 3.1 0.13 12.5 0.4 3.1 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORX88370.1 - 0.0033 17.3 0.8 5.7 6.6 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 ORX88370.1 - 0.0077 16.4 0.6 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 ORX88370.1 - 0.012 14.9 0.4 5.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 ORX88370.1 - 0.033 13.2 0.0 3.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 ORX88370.1 - 0.049 13.1 1.3 11 5.5 0.1 3.6 4 0 0 4 4 4 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORX88370.1 - 0.06 12.7 0.1 8.8 5.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 ORX88370.1 - 0.13 12.6 0.1 32 5.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 ORX88370.1 - 0.16 11.7 0.3 6.6 6.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 ORX88370.1 - 0.93 9.2 3.0 25 4.5 0.1 3.0 2 1 0 2 2 2 0 AAA domain Ribosomal_S7e PF01251.18 ORX88371.1 - 4.2e-11 42.9 0.1 4.8e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e DUF2148 PF09918.9 ORX88371.1 - 0.096 12.7 0.3 0.48 10.5 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) AAL_decarboxy PF03306.13 ORX88372.1 - 2.9e-63 213.1 0.1 3.3e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase RGS PF00615.19 ORX88373.1 - 1.8e-13 50.8 4.0 2.8e-13 50.2 4.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX88373.1 - 0.001 18.9 2.5 0.001 18.9 2.5 2.2 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Prenyltrans PF00432.21 ORX88375.1 - 1.9e-59 197.0 14.6 2.9e-13 49.3 0.2 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORX88375.1 - 5e-06 25.8 0.5 0.00056 19.1 0.0 2.9 1 1 3 4 4 4 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORX88375.1 - 1e-05 24.8 0.0 0.8 8.8 0.0 3.4 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain Peptidase_M50B PF13398.6 ORX88378.1 - 1.6e-56 191.1 15.8 1.9e-56 190.9 15.8 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M41 PF01434.18 ORX88378.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 ER_lumen_recept PF00810.18 ORX88379.1 - 4e-52 177.0 13.4 4e-52 177.0 13.4 1.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORX88379.1 - 0.16 11.7 0.2 0.16 11.7 0.2 3.5 3 1 1 4 4 4 0 PQ loop repeat Peptidase_S8 PF00082.22 ORX88381.1 - 3.7e-29 101.9 5.9 1.1e-28 100.4 5.9 1.7 1 1 0 1 1 1 1 Subtilase family Cid2 PF09774.9 ORX88382.1 - 4.7e-19 69.4 4.8 2.4e-18 67.1 4.8 2.1 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF1987 PF09345.10 ORX88382.1 - 0.013 15.2 0.2 0.018 14.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Urocanase_N PF17391.2 ORX88382.1 - 0.11 12.1 0.0 13 5.5 0.0 2.6 3 0 0 3 3 3 0 Urocanase N-terminal domain PK PF00224.21 ORX88383.1 - 3.4e-163 542.5 2.7 4.3e-163 542.2 2.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX88383.1 - 1.2e-37 128.7 0.0 3.3e-37 127.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX88383.1 - 1.8e-06 27.3 0.1 6e-06 25.6 0.0 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 ORX88384.1 - 4.1e-163 542.2 3.1 5.5e-163 541.8 3.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX88384.1 - 4.1e-38 130.2 0.1 1.2e-37 128.7 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX88384.1 - 1.8e-06 27.3 0.2 6.2e-06 25.5 0.0 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family RabGAP-TBC PF00566.18 ORX88385.1 - 4.7e-56 189.8 0.1 4.7e-56 189.8 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HOOK PF05622.12 ORX88385.1 - 0.0013 17.0 21.5 0.0013 17.0 21.5 1.7 2 0 0 2 2 2 1 HOOK protein UPF0242 PF06785.11 ORX88385.1 - 0.0036 17.4 20.3 0.0036 17.4 20.3 2.7 2 2 0 2 2 1 1 Uncharacterised protein family (UPF0242) N-terminus Cor1 PF04803.12 ORX88385.1 - 0.016 15.4 12.6 0.04 14.1 12.6 1.7 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region YabA PF06156.13 ORX88385.1 - 0.02 15.5 7.6 0.02 15.5 7.6 3.5 2 1 1 3 3 3 0 Initiation control protein YabA GAS PF13851.6 ORX88385.1 - 0.18 11.2 29.9 0.086 12.2 20.7 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 ORX88385.1 - 0.25 10.4 21.1 0.48 9.5 17.4 2.7 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 ORX88385.1 - 0.36 10.9 10.5 0.064 13.3 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.18 ORX88385.1 - 0.47 10.7 19.4 0.2 11.9 1.1 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 ORX88385.1 - 0.63 10.2 21.3 3 8.0 3.5 3.7 2 1 1 3 3 3 0 bZIP transcription factor Fungal_TACC PF12709.7 ORX88385.1 - 1.1 9.7 20.0 0.11 12.9 3.2 3.9 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins LPP PF04728.13 ORX88385.1 - 1.2 9.6 8.9 2 8.8 0.1 3.7 3 1 1 4 4 2 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 ORX88385.1 - 1.4 9.1 19.4 0.032 14.3 9.1 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1515 PF07439.11 ORX88385.1 - 1.5 8.9 5.9 0.71 9.9 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) MogR_DNAbind PF12181.8 ORX88385.1 - 1.5 8.7 7.9 0.66 9.9 4.0 2.2 1 1 1 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) Cnn_1N PF07989.11 ORX88385.1 - 2.6 8.3 27.9 0.03 14.5 11.7 4.2 2 1 2 5 5 4 0 Centrosomin N-terminal motif 1 TMPIT PF07851.13 ORX88385.1 - 2.9 7.0 9.6 7 5.8 9.6 1.7 1 0 0 1 1 1 0 TMPIT-like protein IFP_35_N PF07334.13 ORX88385.1 - 6.8 6.9 17.9 1.8 8.7 0.7 3.8 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PhoU PF01895.19 ORX88385.1 - 6.8 7.2 9.2 1.9 9.0 3.0 2.8 2 0 0 2 2 2 0 PhoU domain TSC22 PF01166.18 ORX88385.1 - 8.9 6.7 19.8 3.4 8.0 2.6 4.0 2 1 1 3 3 3 0 TSC-22/dip/bun family Ank_2 PF12796.7 ORX88386.1 - 6.3e-11 42.7 0.2 1.6e-09 38.2 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX88386.1 - 7.2e-10 38.9 0.1 6.1e-05 23.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORX88386.1 - 1.6e-08 34.6 0.0 0.0002 21.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORX88386.1 - 5.6e-08 32.4 0.0 0.0011 19.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORX88386.1 - 4.6e-07 30.3 0.2 0.023 15.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) BCS1_N PF08740.11 ORX88386.1 - 0.085 12.8 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 BCS1 N terminal DUF4878 PF12870.7 ORX88386.1 - 0.2 12.0 0.1 0.75 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Aa_trans PF01490.18 ORX88387.1 - 2.5e-61 207.6 33.1 2.5e-61 207.6 33.1 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX88387.1 - 0.00021 20.5 18.7 0.00021 20.5 18.7 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Fungal_trans PF04082.18 ORX88388.1 - 2.1e-34 118.7 0.0 4.5e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX88388.1 - 5e-11 42.5 10.8 1.1e-10 41.4 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3533 PF12051.8 ORX88389.1 - 2.6e-16 59.5 13.2 4e-16 58.9 13.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 ORX88389.1 - 1.3e-10 41.0 15.0 1.6e-10 40.7 15.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein NICE-3 PF07406.11 ORX88390.1 - 7.2e-08 32.6 0.0 8.8e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 ORX88390.1 - 0.064 13.5 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) SH3_9 PF14604.6 ORX88392.1 - 5.8e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX88392.1 - 2.3e-05 23.9 0.0 4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain fn2 PF00040.19 ORX88392.1 - 0.00033 20.9 0.6 0.00072 19.8 0.6 1.6 1 0 0 1 1 1 1 Fibronectin type II domain SH3_2 PF07653.17 ORX88392.1 - 0.00036 20.2 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3612 PF12268.8 ORX88392.1 - 0.0096 16.1 0.2 0.015 15.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3612) BLOC1_2 PF10046.9 ORX88393.1 - 1.4e-27 95.8 7.7 1.7e-27 95.5 7.7 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 BLI1 PF17324.2 ORX88393.1 - 0.0057 17.3 5.1 0.012 16.3 5.1 1.6 1 1 0 1 1 1 1 BLOC-1 interactor 1 Med9 PF07544.13 ORX88393.1 - 0.0068 16.5 0.5 0.013 15.6 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 eIF3_subunit PF08597.10 ORX88393.1 - 0.0071 16.3 2.9 0.0083 16.1 2.9 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CDH1_2_SANT_HL1 PF18375.1 ORX88393.1 - 0.0098 16.5 0.4 0.03 15.0 0.0 1.9 1 1 1 2 2 2 1 CDH1/2 SANT-Helical linker 1 Prominin PF05478.11 ORX88393.1 - 0.019 12.9 2.5 0.023 12.7 2.5 1.0 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 ORX88393.1 - 0.04 14.1 5.6 0.13 12.5 1.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AbiJ_NTD4 PF18863.1 ORX88393.1 - 0.041 14.3 1.0 0.051 14.0 1.0 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 PMC2NT PF08066.12 ORX88393.1 - 0.042 14.5 2.9 0.064 13.9 1.3 2.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain LOH1CR12 PF10158.9 ORX88393.1 - 0.044 13.8 0.8 0.064 13.3 0.8 1.4 1 1 0 1 1 1 0 Tumour suppressor protein XhlA PF10779.9 ORX88393.1 - 0.11 12.7 0.6 0.44 10.8 0.1 2.1 1 1 0 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.12 ORX88393.1 - 0.11 12.9 1.8 0.26 11.8 1.2 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.17 ORX88393.1 - 0.14 12.5 3.2 0.32 11.3 1.9 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein AATF-Che1 PF13339.6 ORX88393.1 - 0.24 12.1 4.8 0.12 13.0 1.6 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Carbpep_Y_N PF05388.11 ORX88393.1 - 0.32 11.5 3.2 1.2 9.7 0.7 2.1 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide DUF2120 PF09893.9 ORX88393.1 - 0.41 10.8 3.0 0.97 9.5 3.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) YtxH PF12732.7 ORX88393.1 - 3.5 8.2 5.9 1.1e+02 3.5 5.9 2.7 1 1 0 1 1 1 0 YtxH-like protein WAPL PF07814.13 ORX88394.1 - 1.8e-48 165.2 8.1 3.2e-48 164.4 8.1 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 ORX88394.1 - 0.00058 19.1 2.6 0.02 14.1 0.5 2.4 2 0 0 2 2 2 2 Wap1 domain Dus PF01207.17 ORX88395.1 - 1.4e-57 195.2 0.0 2.2e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 ORX88395.1 - 1.1e-05 25.2 17.4 0.0063 16.4 5.5 3.5 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX88395.1 - 0.021 14.6 17.8 0.15 11.9 6.1 3.2 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX88395.1 - 0.022 14.8 4.8 0.022 14.8 4.8 3.7 4 0 0 4 4 4 0 Zinc finger domain Lustrin_cystein PF14625.6 ORX88395.1 - 0.037 14.4 8.4 0.79 10.1 0.7 2.7 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain Torus PF16131.5 ORX88395.1 - 0.052 14.2 8.6 0.064 14.0 0.7 2.5 1 1 1 2 2 2 0 Torus domain Rhomboid PF01694.22 ORX88396.1 - 0.021 14.8 4.1 0.061 13.3 4.1 1.7 1 0 0 1 1 1 0 Rhomboid family DUF378 PF04070.12 ORX88396.1 - 3.8 7.5 5.7 1.2 9.1 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF378) Peptidase_S24 PF00717.23 ORX88397.1 - 1.1e-09 38.1 0.1 1.7e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S24 PF00717.23 ORX88398.1 - 7.6e-10 38.6 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Csm1 PF12539.8 ORX88399.1 - 2e-11 44.4 1.2 2.6e-10 40.8 1.2 2.5 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Cohesin_HEAT PF12765.7 ORX88399.1 - 0.058 13.7 0.9 0.5 10.7 0.5 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Csm1_N PF18504.1 ORX88399.1 - 0.058 13.7 23.4 0.98 9.8 14.6 3.0 1 1 1 2 2 2 0 Csm1 N-terminal domain FapA PF03961.13 ORX88399.1 - 0.061 11.9 9.7 0.13 10.9 9.7 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Gp-FAR-1 PF05823.12 ORX88399.1 - 0.22 11.9 15.9 0.17 12.2 12.2 2.3 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SpecificRecomb PF10136.9 ORX88399.1 - 0.31 9.3 2.0 0.43 8.8 2.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF4407 PF14362.6 ORX88399.1 - 2.8 7.2 11.6 6.1 6.1 11.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ECH_2 PF16113.5 ORX88401.1 - 2.8e-133 444.6 0.0 3.4e-133 444.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORX88401.1 - 1.3e-31 109.8 0.0 2.7e-29 102.3 0.0 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Mitovir_RNA_pol PF05919.11 ORX88401.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Romo1 PF10247.9 ORX88402.1 - 3.5e-26 91.3 7.0 4e-26 91.2 7.0 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Polysacc_synt_C PF14667.6 ORX88402.1 - 0.01 15.9 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF2567 PF10821.8 ORX88402.1 - 0.072 13.2 0.1 0.078 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DUF3021 PF11457.8 ORX88402.1 - 0.093 13.1 0.5 0.11 12.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Tim17 PF02466.19 ORX88402.1 - 0.099 13.0 4.0 0.13 12.6 4.0 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Sulfate_transp PF00916.20 ORX88403.1 - 2e-112 375.7 19.1 2.6e-112 375.3 19.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX88403.1 - 1.5e-12 47.2 0.0 3.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORX88403.1 - 0.00022 21.5 0.1 0.00048 20.4 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORX88403.1 - 0.02 15.3 1.9 0.02 15.3 1.9 3.3 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily SCPU PF05229.15 ORX88405.1 - 0.031 14.7 0.4 0.045 14.1 0.4 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain Defb50 PF17546.2 ORX88405.1 - 0.045 13.7 0.8 0.096 12.6 0.3 1.8 2 0 0 2 2 2 0 Beta defensin 50 adh_short PF00106.25 ORX88406.1 - 9.4e-15 54.6 5.4 7.4e-06 25.5 1.9 3.2 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 ORX88406.1 - 3.9e-08 33.2 5.0 0.0017 18.0 0.0 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX88406.1 - 2.7e-06 27.4 0.1 4.8e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 ORX88406.1 - 0.00091 19.3 0.2 0.0015 18.6 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORX88406.1 - 0.019 15.4 0.1 0.039 14.4 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PA PF02225.22 ORX88406.1 - 0.021 14.8 0.7 0.041 13.9 0.7 1.5 1 0 0 1 1 1 0 PA domain Acid_phosphat_B PF03767.14 ORX88406.1 - 0.029 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) 2-Hacid_dh_C PF02826.19 ORX88406.1 - 0.042 13.2 0.2 0.07 12.5 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MurB_C PF02873.16 ORX88406.1 - 0.14 12.3 0.3 0.29 11.2 0.3 1.5 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 ORX88408.1 - 2.4e-18 67.0 0.0 3e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Attacin_N PF03768.15 ORX88409.1 - 0.033 14.3 0.3 0.061 13.5 0.3 1.4 1 0 0 1 1 1 0 Attacin, N-terminal region Ribosomal_L1 PF00687.21 ORX88410.1 - 6.3e-47 160.0 1.4 7.7e-47 159.7 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mod_r PF07200.13 ORX88410.1 - 0.041 14.0 1.1 0.25 11.5 0.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FKBP_N_2 PF18023.1 ORX88410.1 - 0.091 12.9 0.3 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 BDBT FKBP like N-terminal Glucosamine_iso PF01182.20 ORX88411.1 - 1.3e-16 61.2 0.0 2.2e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase VCX_VCY PF15231.6 ORX88412.1 - 0.0038 17.9 0.2 0.0038 17.9 0.2 2.8 1 1 1 2 2 2 1 Variable charge X/Y family SRP-alpha_N PF04086.13 ORX88412.1 - 0.054 13.4 3.4 0.073 13.0 3.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RNA_pol_Rpb2_6 PF00562.28 ORX88413.1 - 5.8e-130 433.9 0.0 8.1e-130 433.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORX88413.1 - 1.2e-59 201.2 0.1 1.8e-59 200.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ORX88413.1 - 1e-34 118.8 0.5 2.6e-34 117.5 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ORX88413.1 - 1e-29 103.5 0.4 3.9e-29 101.6 0.6 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 ORX88413.1 - 4.3e-27 94.2 1.4 1.2e-26 92.7 0.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 ORX88413.1 - 6.4e-21 74.3 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ORX88413.1 - 3.9e-09 36.9 3.8 1.7e-08 34.9 3.8 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RecR PF02132.15 ORX88413.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 RecR protein Yip1 PF04893.17 ORX88414.1 - 1.5e-08 34.5 15.1 2.2e-08 34.0 15.1 1.2 1 0 0 1 1 1 1 Yip1 domain FA_desaturase PF00487.24 ORX88414.1 - 1.3 8.8 6.6 3 7.6 6.1 1.8 1 1 1 2 2 2 0 Fatty acid desaturase zf-TFIIIC PF12660.7 ORX88415.1 - 3.4e-16 59.1 1.4 3.4e-16 59.1 1.4 2.0 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex XAF1_C PF18608.1 ORX88415.1 - 0.73 9.4 4.2 18 5.0 0.0 3.2 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain UAA PF08449.11 ORX88416.1 - 7.9e-56 189.5 15.2 9.1e-56 189.3 15.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORX88416.1 - 1.6e-12 47.7 16.3 2.4e-08 34.3 7.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORX88416.1 - 0.0001 21.6 3.6 0.13 11.4 0.3 2.2 1 1 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 ORX88416.1 - 0.00039 19.9 8.6 0.00066 19.1 8.6 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 ORX88416.1 - 0.001 18.1 6.2 0.005 15.8 1.9 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF5516 PF17637.2 ORX88416.1 - 0.13 12.0 2.2 0.37 10.6 2.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5516) TMEM234 PF10639.9 ORX88416.1 - 5.8 7.0 9.7 4.2 7.4 1.2 3.1 2 1 1 3 3 3 0 Putative transmembrane family 234 HMMR_N PF15905.5 ORX88417.1 - 0.0011 18.5 0.5 0.0012 18.4 0.5 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal JIP_LZII PF16471.5 ORX88417.1 - 0.0018 18.4 0.2 0.002 18.3 0.2 1.1 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II Tropomyosin_1 PF12718.7 ORX88417.1 - 0.013 15.6 0.2 0.016 15.4 0.2 1.1 1 0 0 1 1 1 0 Tropomyosin like ABC_tran_CTD PF16326.5 ORX88417.1 - 0.019 15.2 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain Mst1_SARAH PF11629.8 ORX88417.1 - 0.042 13.9 1.6 2.6 8.2 0.0 2.9 1 1 2 3 3 3 0 C terminal SARAH domain of Mst1 Mpp10 PF04006.12 ORX88418.1 - 4.7e-139 464.7 70.6 5.5e-139 464.4 70.6 1.0 1 0 0 1 1 1 1 Mpp10 protein DUF5064 PF16703.5 ORX88418.1 - 0.014 15.8 0.3 0.21 12.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5064) CLPTM1 PF05602.12 ORX88419.1 - 1.8e-146 488.6 5.2 2.1e-146 488.3 5.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 ORX88419.1 - 0.0013 18.5 0.5 0.54 10.1 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1761 PF08570.10 ORX88419.1 - 0.13 12.6 6.1 0.55 10.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) WD40 PF00400.32 ORX88421.1 - 2.3e-22 78.9 14.1 3.6e-05 24.4 0.3 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX88421.1 - 6.8e-06 26.3 0.7 0.87 9.9 0.0 4.6 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX88421.1 - 0.00081 18.4 0.3 0.12 11.3 0.2 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORX88421.1 - 0.0036 15.9 0.2 0.0089 14.6 0.1 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain DUF3992 PF13157.6 ORX88421.1 - 0.021 15.5 1.4 0.082 13.7 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3992) MDM10 PF12519.8 ORX88421.1 - 0.2 10.5 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF4820 PF16091.5 ORX88421.1 - 0.39 10.1 4.9 0.85 8.9 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Lebercilin PF15619.6 ORX88422.1 - 0.00019 21.2 23.0 0.00019 21.2 23.0 3.0 1 1 2 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease WEMBL PF05701.11 ORX88422.1 - 0.00048 19.0 3.1 0.00048 19.0 3.1 2.0 1 1 1 2 2 2 1 Weak chloroplast movement under blue light ATG16 PF08614.11 ORX88422.1 - 0.0008 19.7 25.2 0.0095 16.2 9.1 2.6 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) Fungal_TACC PF12709.7 ORX88422.1 - 0.0065 16.9 5.2 0.0065 16.9 5.2 3.9 2 2 1 4 4 4 1 Fungal Transforming acidic coiled-coil (TACC) proteins DOT1 PF08123.13 ORX88422.1 - 0.012 15.1 5.8 0.014 15.0 5.0 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 DivIC PF04977.15 ORX88422.1 - 0.03 14.1 1.1 0.03 14.1 1.1 4.4 2 1 2 4 4 4 0 Septum formation initiator T3SSipB PF16535.5 ORX88422.1 - 0.036 14.5 1.4 0.036 14.5 1.4 2.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB Sec20 PF03908.13 ORX88422.1 - 0.3 11.1 12.7 0.66 9.9 1.5 3.6 2 2 1 3 3 3 0 Sec20 DUF3037 PF11236.8 ORX88422.1 - 1.1 9.7 7.5 5.2 7.5 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) ZapB PF06005.12 ORX88422.1 - 1.3 9.5 26.5 0.2 12.1 4.0 4.5 3 2 1 4 4 4 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 ORX88422.1 - 1.8 8.6 29.4 1.5 8.8 5.8 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 ORX88422.1 - 2.4 8.3 19.7 0.19 11.9 0.9 4.4 3 1 1 4 4 4 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 ORX88422.1 - 2.9 8.0 28.4 2.5 8.2 5.6 4.0 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein NEMO PF11577.8 ORX88422.1 - 3.4 7.8 19.0 0.46 10.5 1.9 4.4 2 1 2 4 4 4 0 NF-kappa-B essential modulator NEMO Proteasom_Rpn13 PF04683.13 ORX88423.1 - 1.3e-30 105.8 0.1 1.7e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor MIS13 PF08202.11 ORX88424.1 - 8.3e-45 153.4 8.0 1.4e-44 152.6 8.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family TryThrA_C PF12319.8 ORX88424.1 - 0.0043 16.6 7.6 0.0043 16.6 7.6 1.6 2 0 0 2 2 2 1 Tryptophan-Threonine-rich plasmodium antigen C terminal Cue1_U7BR PF18499.1 ORX88424.1 - 0.059 13.4 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Vma12 PF11712.8 ORX88424.1 - 0.17 11.9 2.5 0.5 10.4 2.4 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ribosomal_L5e PF17144.4 ORX88425.1 - 1.3e-86 288.6 0.3 1.3e-86 288.6 0.3 2.6 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORX88425.1 - 1.3e-31 109.4 8.9 1.3e-31 109.4 8.9 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region eIF-3_zeta PF05091.12 ORX88426.1 - 8.3e-202 671.8 0.0 9.6e-202 671.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 ORX88426.1 - 0.0014 18.2 0.0 0.89 9.0 0.0 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated gene protein 2 C-terminus HhH-GPD PF00730.25 ORX88427.1 - 1e-20 74.2 0.0 3.1e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 ORX88427.1 - 1.4e-13 50.8 0.1 3.3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 ORX88427.1 - 7e-06 25.6 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ORX88427.1 - 0.027 15.1 0.0 2.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.8 ORX88427.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus EndIII_4Fe-2S PF10576.9 ORX88427.1 - 4.3 7.8 11.0 0.16 12.3 5.0 1.9 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III CAP PF00188.26 ORX88428.1 - 8.7e-18 65.4 0.2 1.1e-17 65.0 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family YadA_stalk PF05662.14 ORX88428.1 - 0.081 13.3 0.7 0.23 11.8 0.1 2.1 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin NUDE_C PF04880.13 ORX88428.1 - 0.15 12.6 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region RNase_T PF00929.24 ORX88429.1 - 8.7e-16 58.9 0.2 8.1e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 Exonuclease DUF966 PF06136.13 ORX88429.1 - 0.62 9.7 19.3 1 9.0 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF5462 PF17547.2 ORX88429.1 - 2.9 7.2 10.6 0.34 10.3 4.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5462) Beta-lactamase PF00144.24 ORX88430.1 - 4.3e-43 147.8 0.0 5.8e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase RGS PF00615.19 ORX88431.1 - 2.6e-10 40.6 2.5 4.1e-10 39.9 2.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Hydrolase_4 PF12146.8 ORX88432.1 - 1.9e-09 37.2 0.1 1.9e-07 30.6 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ORX88432.1 - 4.4e-09 36.2 0.2 1.6e-08 34.3 0.2 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ORX88432.1 - 2e-07 30.0 0.1 1.2e-05 24.1 0.1 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ORX88432.1 - 4.4e-06 26.8 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 ORX88432.1 - 7.8e-05 22.4 0.0 0.00015 21.4 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ORX88432.1 - 0.00054 19.5 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.11 ORX88432.1 - 0.0074 15.1 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 ORX88432.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ORX88432.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 ORX88432.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) GRP PF07172.11 ORX88433.1 - 1.7 9.4 7.1 3 8.6 6.4 1.7 2 0 0 2 2 2 0 Glycine rich protein family PRAP PF15314.6 ORX88434.1 - 0.012 16.1 4.2 0.039 14.4 4.2 1.9 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine DUF1769 PF08588.10 ORX88435.1 - 1.2e-13 51.0 0.2 2.5e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) CPDase PF07823.11 ORX88436.1 - 8.4e-21 74.6 0.0 3e-20 72.8 0.0 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 ORX88436.1 - 1.4e-08 34.8 0.6 7e-05 22.8 0.1 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 ORX88436.1 - 0.022 15.0 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 LigT like Phosphoesterase His_Phos_1 PF00300.22 ORX88437.1 - 1.3e-28 100.1 0.0 1.5e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C14 PF00656.22 ORX88438.1 - 2.3e-60 204.6 0.0 3.1e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain 17kDa_Anti_2 PF16998.5 ORX88439.1 - 0.098 12.6 0.9 0.15 12.0 0.9 1.3 1 0 0 1 1 1 0 17 kDa outer membrane surface antigen Zip PF02535.22 ORX88439.1 - 4 6.6 5.1 5 6.2 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter zf-C2H2 PF00096.26 ORX88440.1 - 9.2e-09 35.3 18.5 0.00033 21.0 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORX88440.1 - 0.00011 22.8 8.1 0.0033 18.0 0.4 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORX88440.1 - 0.0025 18.5 1.1 0.0025 18.5 1.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX88440.1 - 0.003 17.9 4.4 0.003 17.9 4.4 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX88440.1 - 0.0069 16.7 2.3 0.0074 16.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX88440.1 - 0.024 15.0 2.5 0.048 14.0 2.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 ORX88440.1 - 0.033 14.3 0.5 0.033 14.3 0.5 3.1 3 1 0 3 3 3 0 Zic proteins zinc finger domain ADD_ATRX PF17981.1 ORX88440.1 - 0.063 13.1 2.3 0.14 12.1 2.3 1.6 1 0 0 1 1 1 0 Cysteine Rich ADD domain zf-TRAF PF02176.18 ORX88440.1 - 0.19 12.4 6.1 0.14 12.9 2.8 2.4 2 1 0 2 2 2 0 TRAF-type zinc finger Corazonin PF17308.2 ORX88442.1 - 0.0092 16.4 0.2 0.029 14.7 0.2 1.8 1 0 0 1 1 1 1 Pro-corazonin FliJ PF02050.16 ORX88442.1 - 0.012 15.9 4.5 0.15 12.2 0.3 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein DUF5082 PF16888.5 ORX88442.1 - 0.08 13.2 0.2 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Cor1 PF04803.12 ORX88442.1 - 0.93 9.7 3.9 3.2 8.0 0.1 2.8 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF4250 PF14056.6 ORX88442.1 - 2 8.4 4.4 5.1 7.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) N6_N4_Mtase PF01555.18 ORX88443.1 - 0.18 11.5 6.1 0.28 10.9 6.1 1.2 1 0 0 1 1 1 0 DNA methylase Lin-8 PF03353.15 ORX88443.1 - 7.6 6.0 11.1 9.8 5.6 11.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cg6151-P PF10233.9 ORX88444.1 - 1e-22 80.6 11.8 1.2e-22 80.3 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P OSTMP1 PF09777.9 ORX88444.1 - 1 8.7 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3040 PF11239.8 ORX88444.1 - 1 9.6 4.8 0.41 10.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF373 PF04123.13 ORX88444.1 - 5.8 6.3 8.0 17 4.7 8.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PH_12 PF16457.5 ORX88446.1 - 0.056 14.0 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain HTH_19 PF12844.7 ORX88446.1 - 0.15 12.1 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF5312 PF17239.2 ORX88447.1 - 0.027 12.8 0.4 0.031 12.6 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) DUF3512 PF12024.8 ORX88447.1 - 0.063 12.8 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) PH_12 PF16457.5 ORX88448.1 - 0.11 13.1 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Gp5_C PF06715.12 ORX88448.1 - 0.4 10.9 1.6 9.7 6.6 0.2 2.5 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) DUF1772 PF08592.11 ORX88449.1 - 7.2e-17 62.0 0.4 9.1e-17 61.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NADHdeh_related PF10125.9 ORX88449.1 - 0.019 14.4 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein Gti1_Pac2 PF09729.9 ORX88450.1 - 5e-47 160.3 0.8 2.8e-40 138.3 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family SRP72 PF08492.12 ORX88451.1 - 1.3e-15 57.6 15.1 1.3e-15 57.6 15.1 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 ORX88451.1 - 1.2e-14 54.3 7.0 1.2e-14 54.3 7.0 2.5 3 1 0 3 3 3 1 Putative TPR-like repeat TPR_2 PF07719.17 ORX88451.1 - 6.1e-11 41.6 18.4 0.016 15.2 0.5 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX88451.1 - 1.2e-10 41.3 5.0 5.9 8.0 0.5 8.5 8 3 3 11 11 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX88451.1 - 1e-07 32.1 21.0 0.0061 16.8 0.1 6.2 4 3 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORX88451.1 - 1.6e-06 28.5 22.9 0.049 14.1 2.0 7.4 4 3 6 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX88451.1 - 1.9e-06 28.0 20.1 0.51 10.7 2.0 6.9 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX88451.1 - 2.6e-06 27.0 13.9 0.44 10.4 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORX88451.1 - 9.9e-06 26.1 6.9 7.5 7.3 0.2 6.3 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX88451.1 - 4.3e-05 23.2 3.8 8.4 6.4 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 ORX88451.1 - 0.00014 21.8 0.5 0.001 19.0 0.2 2.7 2 0 0 2 2 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORX88451.1 - 0.002 18.2 8.6 0.095 12.8 0.0 5.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 ORX88451.1 - 0.012 15.8 12.2 11 6.5 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORX88451.1 - 0.046 14.1 2.8 1.5e+02 3.1 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 ORX88451.1 - 0.52 10.7 5.6 62 4.0 0.0 4.3 3 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 ORX88451.1 - 0.97 10.2 13.2 27 5.7 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORX88451.1 - 1.2 8.8 4.5 2.6 7.7 0.5 3.4 4 1 1 5 5 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4288 PF14119.6 ORX88451.1 - 1.5 9.3 5.7 0.54 10.7 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) TPR_9 PF13371.6 ORX88451.1 - 2.1 8.5 4.9 7.4 6.8 0.0 4.3 5 1 1 6 6 5 0 Tetratricopeptide repeat AAA_12 PF13087.6 ORX88451.1 - 6.4 6.3 10.5 0.51 9.9 1.6 2.4 2 0 0 2 2 2 0 AAA domain SDA1 PF05285.12 ORX88453.1 - 1.7e-83 281.0 44.9 3e-45 155.2 9.7 3.1 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 ORX88453.1 - 3.7e-05 24.0 0.9 0.00014 22.1 0.3 2.3 2 0 0 2 2 2 1 NUC130/3NT domain YL1 PF05764.13 ORX88453.1 - 0.0026 17.9 29.1 0.058 13.5 21.5 2.2 2 0 0 2 2 2 2 YL1 nuclear protein DUF262 PF03235.14 ORX88454.1 - 1.9e-15 57.7 0.2 5.1e-15 56.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF262 UDPGP PF01704.18 ORX88455.1 - 2.8e-58 197.5 0.0 3.7e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORX88455.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Adaptin_N PF01602.20 ORX88456.1 - 1.9e-145 485.4 8.2 2.3e-145 485.1 8.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORX88456.1 - 3.2e-18 66.3 8.1 1.5e-16 60.9 0.3 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX88456.1 - 1.5e-06 28.5 0.0 0.16 12.4 0.0 4.0 2 2 2 4 4 4 3 HEAT repeats SPO22 PF08631.10 ORX88456.1 - 0.00016 21.3 0.3 0.0068 15.9 0.0 2.3 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like HEAT PF02985.22 ORX88456.1 - 0.0014 18.7 0.6 38 4.9 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat Cohesin_HEAT PF12765.7 ORX88456.1 - 0.044 14.1 0.2 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_UF PF18817.1 ORX88456.1 - 0.12 12.6 0.4 24 5.3 0.0 3.7 4 0 0 4 4 4 0 Repeat of uncharacterized protein PH0542 PP2C PF00481.21 ORX88457.1 - 6.6e-48 163.6 0.0 1e-47 162.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 ORX88457.1 - 1.3e-42 143.3 75.3 6.8e-10 38.6 8.0 10.4 6 2 6 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 ORX88457.1 - 2.8e-38 129.3 86.2 2.6e-05 24.5 0.9 13.4 3 2 15 18 18 18 16 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ORX88457.1 - 5.6e-29 101.1 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RA PF00788.23 ORX88457.1 - 2e-05 25.1 0.0 4.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 ORX88457.1 - 0.00049 20.1 14.2 0.099 12.6 1.5 4.5 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 ORX88457.1 - 0.0016 18.0 22.6 0.15 11.6 2.3 5.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 ORX88457.1 - 0.0024 18.2 72.9 4.2 8.3 0.1 18.1 18 1 1 19 19 19 1 Leucine Rich Repeat FEZ PF07763.13 ORX88457.1 - 0.28 10.9 0.9 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 FEZ-like protein LRR_6 PF13516.6 ORX88457.1 - 0.57 10.4 66.1 3.5 7.9 0.1 15.3 16 0 0 16 16 16 0 Leucine Rich repeat zf-C2H2 PF00096.26 ORX88458.1 - 4.1e-14 52.1 15.0 4.8e-07 29.9 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX88458.1 - 2.1e-10 40.5 11.8 2e-08 34.2 1.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX88458.1 - 7.4e-09 35.7 12.0 0.00023 21.7 6.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX88458.1 - 5e-06 26.6 4.3 0.00056 20.1 3.6 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX88458.1 - 0.00075 19.8 5.2 0.013 15.8 2.2 2.4 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX88458.1 - 0.0015 18.4 2.3 0.95 9.4 0.0 2.4 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 ORX88458.1 - 0.0051 17.1 0.9 0.0076 16.5 0.9 1.4 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORX88458.1 - 0.015 15.3 9.3 2.3 8.3 7.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 ORX88458.1 - 0.024 15.3 1.1 0.36 11.5 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 ORX88458.1 - 0.035 13.9 0.8 1 9.3 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 ORX88458.1 - 0.25 11.8 5.3 0.14 12.6 3.2 1.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 ORX88458.1 - 0.57 10.5 5.5 1.1 9.6 3.3 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 ORX88458.1 - 1 9.0 5.3 4.9 6.9 2.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 ORX88458.1 - 2.1 8.4 8.2 6 7.0 8.2 1.9 1 1 0 1 1 1 0 BED zinc finger Ras PF00071.22 ORX88460.1 - 3.8e-67 224.9 0.2 4.4e-67 224.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX88460.1 - 4.1e-36 123.8 0.0 6.5e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX88460.1 - 4e-17 62.2 0.0 5.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX88460.1 - 4.5e-07 29.4 0.0 5.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX88460.1 - 8.3e-06 25.5 0.7 1.9e-05 24.3 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX88460.1 - 1.8e-05 24.8 0.0 3.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX88460.1 - 4.1e-05 23.6 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORX88460.1 - 0.0014 18.1 0.1 0.0017 17.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ORX88460.1 - 0.0063 16.1 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 ORX88460.1 - 0.0065 16.2 0.2 1.3 8.8 0.0 2.8 1 1 2 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ORX88460.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ORX88460.1 - 0.072 13.5 0.0 0.52 10.7 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX88460.1 - 0.072 13.5 0.0 0.091 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 ORX88460.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 ORX88460.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 ORX88460.1 - 0.092 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GCP_C_terminal PF04130.13 ORX88461.1 - 3.9e-47 161.2 1.2 3.9e-47 161.2 1.2 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORX88461.1 - 6.1e-33 114.7 3.9 2.1e-32 113.0 3.8 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DDE_Tnp_IS240 PF13610.6 ORX88461.1 - 0.043 14.1 0.6 0.14 12.4 0.6 1.9 1 0 0 1 1 1 0 DDE domain DUF5432 PF17497.2 ORX88461.1 - 0.064 13.4 0.1 0.43 10.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5432) Pro_isomerase PF00160.21 ORX88462.1 - 6.8e-49 166.2 0.0 7.8e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4885 PF16226.5 ORX88462.1 - 0.046 12.8 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) SlyX PF04102.12 ORX88463.1 - 0.029 15.0 2.9 1.8 9.3 0.0 2.9 2 0 0 2 2 2 0 SlyX SOAR PF16533.5 ORX88463.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.0 3 0 0 3 3 3 0 STIM1 Orai1-activating region DUF1664 PF07889.12 ORX88463.1 - 0.28 11.2 1.1 0.71 9.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FUSC PF04632.12 ORX88463.1 - 0.35 9.4 2.0 0.54 8.7 2.0 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family KxDL PF10241.9 ORX88463.1 - 0.4 11.0 5.6 0.19 12.0 2.6 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein PGA2 PF07543.12 ORX88463.1 - 1 9.3 14.6 2 8.4 3.2 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 Peptidase_U57 PF05582.12 ORX88463.1 - 2.2 7.4 4.3 0.38 10.0 0.3 1.6 2 0 0 2 2 2 0 YabG peptidase U57 Tcf25 PF04910.14 ORX88464.1 - 1.9e-104 349.6 4.4 1.9e-104 349.6 4.4 1.4 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Ribosomal_L13 PF00572.18 ORX88465.1 - 4e-11 43.3 0.1 4e-09 36.8 0.0 2.8 2 1 0 2 2 2 1 Ribosomal protein L13 AAA_5 PF07728.14 ORX88467.1 - 0.053 13.5 0.0 0.087 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-SCNM1 PF15803.5 ORX88467.1 - 0.18 11.5 0.4 0.62 9.8 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 MFS_1 PF07690.16 ORX88468.1 - 1.9e-28 99.4 42.5 4e-19 68.8 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PalH PF08733.10 ORX88468.1 - 0.14 11.2 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 PalH/RIM21 DUF2721 PF11026.8 ORX88468.1 - 1.9 8.4 0.0 1.9 8.4 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) Polysacc_deac_1 PF01522.21 ORX88469.1 - 1.6e-29 102.3 0.0 2.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase MSP1_C PF07462.11 ORX88469.1 - 0.31 9.7 4.1 0.45 9.2 4.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ApoLp-III PF07464.11 ORX88469.1 - 3.1 7.9 6.7 0.76 9.9 0.1 2.6 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Peptidase_S41 PF03572.18 ORX88470.1 - 7.4e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Polysacc_deac_1 PF01522.21 ORX88471.1 - 3.9e-31 107.5 0.0 7.6e-31 106.6 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX88471.1 - 0.0023 17.2 0.0 0.0032 16.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX88471.1 - 0.052 13.2 0.6 0.11 12.1 0.6 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DHDPS PF00701.22 ORX88471.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family PALP PF00291.25 ORX88472.1 - 2.6e-66 224.0 0.1 3.5e-66 223.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORX88472.1 - 7.3e-15 55.2 0.2 1.5e-09 38.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain Methyltransf_12 PF08242.12 ORX88472.1 - 0.17 12.7 0.0 0.63 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Clr5 PF14420.6 ORX88472.1 - 8.3 6.7 7.0 1.3e+02 2.9 2.7 3.3 2 1 1 3 3 3 0 Clr5 domain Pyr_redox_2 PF07992.14 ORX88473.1 - 8.8e-49 166.3 0.0 1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX88473.1 - 1.7e-12 47.8 0.0 5.4e-09 36.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 ORX88474.1 - 4.6e-22 78.0 0.1 8e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 ORX88474.1 - 0.0069 16.7 0.0 0.0088 16.3 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 ORX88474.1 - 0.023 15.1 0.3 0.028 14.8 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain SH3BGR PF04908.15 ORX88474.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 ORX88474.1 - 0.099 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 ORX88474.1 - 0.18 11.6 0.2 0.35 10.6 0.2 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain RBB1NT PF08169.11 ORX88475.1 - 6.9e-05 22.9 0.0 0.00024 21.2 0.0 2.0 1 0 0 1 1 1 1 RBB1NT (NUC162) domain PWWP PF00855.17 ORX88475.1 - 0.00017 21.9 0.4 0.00066 20.0 0.4 2.0 1 0 0 1 1 1 1 PWWP domain SET PF00856.28 ORX88476.1 - 1.6e-10 41.7 0.2 2.2e-08 34.7 0.0 2.1 1 1 0 2 2 2 2 SET domain Arginase PF00491.21 ORX88477.1 - 1.7e-73 247.6 0.0 2e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family GATA PF00320.27 ORX88478.1 - 1.9e-16 59.3 3.5 5.5e-16 57.9 3.5 1.9 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 ORX88478.1 - 1.1e-13 50.7 1.4 2.6e-13 49.5 1.4 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1647 PF07801.11 ORX88479.1 - 0.00044 20.0 0.1 0.00072 19.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Pet191_N PF10203.9 ORX88481.1 - 1.4e-24 86.2 7.3 1.6e-24 86.0 7.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 ORX88481.1 - 0.064 13.3 5.5 0.52 10.4 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PIG-S PF10510.9 ORX88482.1 - 7.9e-146 486.9 17.8 9e-146 486.7 17.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Endonuc-BsobI PF09194.10 ORX88482.1 - 0.0091 15.2 0.4 0.038 13.2 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease BsobI DUF2730 PF10805.8 ORX88482.1 - 0.037 14.1 0.2 0.092 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SH3_9 PF14604.6 ORX88483.1 - 1.3e-10 41.0 0.3 3.2e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain fn2 PF00040.19 ORX88483.1 - 3.8e-06 27.1 4.6 3.8e-06 27.1 4.6 2.0 2 0 0 2 2 2 1 Fibronectin type II domain SH3_1 PF00018.28 ORX88483.1 - 2.1e-05 24.0 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX88483.1 - 0.0047 16.6 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kringle PF00051.18 ORX88483.1 - 0.075 13.4 1.2 0.19 12.0 1.2 1.6 1 0 0 1 1 1 0 Kringle domain DUF1180 PF06679.12 ORX88483.1 - 0.16 12.3 1.3 0.31 11.5 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1977 PF09320.11 ORX88484.1 - 4.3e-25 88.0 4.5 1e-24 86.8 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 ORX88484.1 - 4.9e-25 87.4 0.1 1.3e-24 86.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain ANAPC3 PF12895.7 ORX88484.1 - 0.12 12.6 1.4 4.2 7.6 0.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L37e PF01907.19 ORX88485.1 - 1.1e-27 95.9 13.0 1.8e-27 95.2 13.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX88485.1 - 0.0061 16.6 1.6 0.0097 15.9 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORX88485.1 - 0.034 14.1 0.9 0.049 13.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORX88485.1 - 0.22 11.0 3.5 2.2 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORX88485.1 - 0.7 9.8 5.4 1.1 9.1 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF5349 PF17298.2 ORX88486.1 - 0.028 14.2 1.7 0.041 13.7 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) GATA PF00320.27 ORX88487.1 - 3e-17 61.9 2.5 3.7e-17 61.6 2.5 1.1 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX88487.1 - 0.0022 17.5 0.2 0.0028 17.1 0.2 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX88487.1 - 0.059 13.5 0.5 0.074 13.2 0.5 1.2 1 0 0 1 1 1 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORX88487.1 - 0.15 12.3 1.0 0.2 11.9 1.0 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pyridoxal_deC PF00282.19 ORX88488.1 - 4.7e-63 213.1 0.0 7.5e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORX88488.1 - 0.028 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V GATase_2 PF00310.21 ORX88489.1 - 6.3e-183 608.2 0.0 8.5e-183 607.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORX88489.1 - 2.2e-158 527.2 0.1 1.4e-157 524.5 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORX88489.1 - 1.7e-116 388.6 0.0 1.5e-114 382.2 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 ORX88489.1 - 5.8e-89 296.7 5.2 1.1e-88 295.8 5.2 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ORX88489.1 - 5.9e-26 91.4 0.0 3.8e-25 88.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ORX88489.1 - 9e-24 83.4 0.1 2.5e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 ORX88489.1 - 1.7e-09 38.1 0.1 0.0001 22.8 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX88489.1 - 9.5e-09 35.4 0.0 1.1e-07 32.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX88489.1 - 3.7e-07 29.7 0.0 0.0006 19.2 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX88489.1 - 2.5e-05 23.2 0.2 2.5e-05 23.2 0.2 2.2 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 ORX88489.1 - 5.1e-05 22.7 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORX88489.1 - 0.00012 21.5 0.1 0.0003 20.3 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX88489.1 - 0.00031 20.1 0.1 0.032 13.5 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORX88489.1 - 0.00035 21.0 0.6 0.51 10.8 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ORX88489.1 - 0.00062 19.1 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ORX88489.1 - 0.00063 18.9 0.0 0.00063 18.9 0.0 2.6 3 0 0 3 3 2 1 FAD binding domain DAO PF01266.24 ORX88489.1 - 0.00073 19.2 4.7 0.0045 16.6 0.1 3.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORX88489.1 - 0.0058 15.9 0.3 0.023 14.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 ORX88489.1 - 0.009 15.1 3.2 0.1 11.7 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ORX88489.1 - 0.01 15.2 0.1 0.049 13.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.19 ORX88489.1 - 0.025 13.0 0.0 1.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 ORX88489.1 - 0.03 13.3 1.4 0.19 10.7 1.8 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.23 ORX88489.1 - 0.031 14.3 0.1 0.093 12.7 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 ORX88489.1 - 0.031 14.4 0.3 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORX88489.1 - 0.056 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORX88489.1 - 0.065 12.3 1.4 0.61 9.1 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein GATase_6 PF13522.6 ORX88489.1 - 0.083 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_9 PF13454.6 ORX88489.1 - 0.12 12.4 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding IlvN PF07991.12 ORX88489.1 - 0.14 11.7 0.2 0.43 10.1 0.1 1.8 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ORX88489.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 ORX88489.1 - 0.2 11.7 0.5 3.2 7.8 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase PMT PF02366.18 ORX88490.1 - 1.1e-83 280.6 21.3 1.1e-83 280.6 21.3 2.0 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX88490.1 - 3.5e-58 196.5 13.9 3.5e-58 196.5 13.9 3.0 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX88490.1 - 5.1e-33 114.5 2.7 6.2e-33 114.2 1.9 1.4 1 1 1 2 2 2 1 MIR domain PMT_2 PF13231.6 ORX88490.1 - 1.1e-06 29.0 14.9 1.1e-06 29.0 14.9 2.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Tom5 PF10642.9 ORX88490.1 - 0.45 10.6 3.2 1.6 8.9 3.2 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Cob_adeno_trans PF01923.18 ORX88491.1 - 1.5e-54 184.6 0.0 1.8e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase KH_1 PF00013.29 ORX88492.1 - 1.1e-56 188.5 7.3 3.4e-18 65.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX88492.1 - 1.4e-13 50.5 7.2 0.00036 20.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX88492.1 - 3.7e-12 45.9 3.1 0.0014 18.4 0.2 3.4 3 0 0 3 3 3 3 KH domain DUF1876 PF08962.11 ORX88492.1 - 0.0053 16.7 0.7 0.055 13.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1876) MOEP19 PF16005.5 ORX88492.1 - 0.016 15.2 0.0 4.7 7.3 0.0 2.7 3 0 0 3 3 3 0 KH-like RNA-binding domain KH_5 PF13184.6 ORX88492.1 - 0.089 12.9 3.0 11 6.2 0.1 3.3 3 0 0 3 3 3 0 NusA-like KH domain Pkinase PF00069.25 ORX88493.1 - 2.3e-61 207.5 0.0 2.6e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88493.1 - 6.4e-30 104.3 0.0 7.8e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX88493.1 - 2.2e-08 33.8 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX88493.1 - 0.00059 18.9 0.0 0.00086 18.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX88493.1 - 0.00093 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX88493.1 - 0.035 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 ORX88493.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 ORX88493.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nucleoporin_C PF03177.14 ORX88494.1 - 2e-90 304.3 13.2 2.7e-90 303.8 13.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 ORX88494.1 - 5.3e-29 101.2 0.0 9.4e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like zf-CHY PF05495.12 ORX88495.1 - 6.4e-20 71.4 19.1 6.4e-20 71.4 19.1 3.9 2 1 1 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 ORX88495.1 - 6.5e-19 67.7 0.7 6.5e-19 67.7 0.7 4.7 3 2 2 5 5 5 1 Zinc-ribbon zf-RING_2 PF13639.6 ORX88495.1 - 8.3e-09 35.6 9.8 8.3e-09 35.6 9.8 5.0 3 1 2 6 6 6 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORX88495.1 - 1.9e-05 24.4 8.2 1.9e-05 24.4 8.2 5.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX88495.1 - 0.00015 21.5 12.1 0.00015 21.5 12.1 6.0 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX88495.1 - 0.005 16.5 6.2 0.005 16.5 6.2 4.7 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 ORX88495.1 - 0.0099 15.9 8.9 0.0099 15.9 8.9 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX88495.1 - 0.028 14.4 13.1 0.028 14.4 13.1 6.6 3 2 2 5 5 5 0 zinc-RING finger domain Styelin PF17562.2 ORX88495.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Styelin FAR1 PF03101.15 ORX88496.1 - 1.5e-06 28.8 1.3 2.6e-06 28.0 1.3 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORX88497.1 - 3.1e-15 56.3 2.3 3.1e-15 56.3 2.3 2.3 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX88497.1 - 3.3e-05 24.1 0.7 3.3e-05 24.1 0.7 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 ORX88497.1 - 0.0016 18.5 3.2 0.0044 17.1 3.2 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX88497.1 - 0.032 14.5 3.4 0.13 12.5 3.4 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF2938 PF11158.8 ORX88498.1 - 2.1 7.8 5.7 1.2 8.6 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2938) Sulf_transp PF04143.14 ORX88499.1 - 6e-10 39.2 26.0 2.5e-09 37.1 4.9 3.1 1 1 2 3 3 3 2 Sulphur transport Pyr_redox_2 PF07992.14 ORX88502.1 - 1.4e-60 205.1 0.0 1.9e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX88502.1 - 2.3e-16 60.1 1.5 1.4e-15 57.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX88502.1 - 5.4e-12 45.6 0.1 7.5e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX88502.1 - 2.6e-08 34.0 3.7 0.003 17.8 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX88502.1 - 3.3e-05 23.9 1.7 2.4 8.1 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX88502.1 - 0.00012 21.3 3.1 0.067 12.2 0.4 3.0 2 1 1 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 ORX88502.1 - 0.0003 20.5 6.7 0.36 10.4 0.6 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX88502.1 - 0.00078 18.3 5.2 1.2 7.8 0.0 3.5 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 ORX88502.1 - 0.00082 18.6 3.9 1.7 7.7 0.4 3.2 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 ORX88502.1 - 0.0054 15.9 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 ORX88502.1 - 0.007 16.0 0.1 0.028 14.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) 3HCDH_N PF02737.18 ORX88502.1 - 0.037 13.9 0.7 0.074 12.9 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_dim PF02852.22 ORX88502.1 - 0.052 13.8 0.8 7.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain ThiF PF00899.21 ORX88502.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.24 ORX88502.1 - 0.079 12.2 0.0 0.76 9.0 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ORX88502.1 - 0.1 11.8 0.1 0.1 11.8 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 ORX88502.1 - 0.12 12.6 0.7 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain LMBR1 PF04791.16 ORX88503.1 - 1.5e-133 446.5 17.8 1.7e-133 446.2 17.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Holin_9 PF16936.5 ORX88503.1 - 0.23 11.6 2.9 0.21 11.8 0.4 2.1 2 0 0 2 2 2 0 Putative holin PHO4 PF01384.20 ORX88503.1 - 1.2 8.2 3.5 5.2 6.0 3.5 2.3 1 1 0 1 1 1 0 Phosphate transporter family Chs7 PF12271.8 ORX88504.1 - 4.2e-83 279.0 15.2 5.2e-83 278.7 15.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4134 PF13572.6 ORX88504.1 - 0.014 15.6 1.3 0.014 15.6 1.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) DEAD PF00270.29 ORX88505.1 - 7.2e-51 172.4 0.2 2.1e-50 170.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX88505.1 - 6.3e-25 87.7 0.6 1.1e-23 83.6 0.4 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 ORX88505.1 - 5.7e-17 61.7 3.0 5.7e-17 61.7 3.0 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain HNH_5 PF14279.6 ORX88506.1 - 0.051 13.4 4.0 0.1 12.4 4.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Mob1_phocein PF03637.17 ORX88508.1 - 5.2e-32 111.2 1.7 6.6e-32 110.9 1.7 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_S2 PF00318.20 ORX88509.1 - 8.4e-29 100.3 0.9 1.4e-14 53.9 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORX88509.1 - 6.8e-07 30.6 15.7 1.4e-06 29.6 15.7 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Peripla_BP_1 PF00532.21 ORX88509.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family His_Phos_1 PF00300.22 ORX88510.1 - 2.9e-39 134.8 0.0 3.7e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C24 PF03510.14 ORX88510.1 - 0.052 14.0 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family zf-H2C2_2 PF13465.6 ORX88511.1 - 8.5e-16 57.6 23.6 3.5e-06 27.2 1.0 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX88511.1 - 1e-13 50.9 30.1 8e-06 26.0 0.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX88511.1 - 1.2e-09 38.1 26.6 0.00048 20.7 0.4 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 ORX88511.1 - 0.00025 21.3 12.1 0.022 15.2 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX88511.1 - 0.00056 20.1 12.8 0.59 10.5 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX88511.1 - 0.0008 20.0 9.5 0.1 13.2 1.8 2.6 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 ORX88511.1 - 0.00099 19.1 4.9 0.037 14.1 0.7 4.6 4 2 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX88511.1 - 0.0066 16.7 8.9 0.045 14.1 3.4 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX88511.1 - 0.033 14.9 7.7 0.31 11.8 3.2 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger BolA PF01722.18 ORX88511.1 - 0.19 12.0 1.5 2.6 8.4 0.2 2.2 1 1 1 2 2 2 0 BolA-like protein zf-C2H2 PF00096.26 ORX88512.1 - 9.9e-22 76.1 27.0 3.1e-05 24.2 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX88512.1 - 1.1e-15 57.3 20.9 4.4e-05 23.7 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX88512.1 - 5.7e-12 45.4 28.5 0.0011 19.6 0.9 4.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX88512.1 - 0.00028 20.8 15.9 0.12 12.4 0.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORX88512.1 - 0.00058 20.4 6.1 2.2 9.0 1.3 3.3 2 1 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX88512.1 - 0.0011 19.1 11.7 3.2 8.2 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX88512.1 - 0.0017 19.0 8.7 0.036 14.7 0.7 3.3 2 1 1 3 3 3 1 TRAF-type zinc finger zf-met PF12874.7 ORX88512.1 - 0.0056 17.0 14.3 7.8 7.0 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type CHORD PF04968.12 ORX88512.1 - 0.096 13.4 12.5 3.5 8.4 2.8 3.4 3 0 0 3 3 3 0 CHORD zf-C2H2_aberr PF17017.5 ORX88512.1 - 0.12 12.5 5.9 2.2 8.4 2.2 3.1 3 1 0 3 3 3 0 Aberrant zinc-finger INO80_Ies4 PF08193.11 ORX88512.1 - 0.15 12.0 7.3 0.23 11.4 7.3 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 zf-C2H2 PF00096.26 ORX88513.1 - 1e-21 76.1 27.0 3.1e-05 24.2 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX88513.1 - 1.1e-15 57.2 20.9 4.4e-05 23.7 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX88513.1 - 6e-12 45.3 28.5 0.0011 19.6 0.9 4.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX88513.1 - 0.00029 20.8 15.9 0.12 12.4 0.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORX88513.1 - 0.00059 20.4 6.1 2.2 9.0 1.3 3.3 2 1 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX88513.1 - 0.0012 19.1 11.7 3.2 8.1 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX88513.1 - 0.0018 19.0 8.7 0.037 14.7 0.7 3.3 2 1 1 3 3 3 1 TRAF-type zinc finger zf-met PF12874.7 ORX88513.1 - 0.0058 17.0 14.3 7.9 7.0 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type CHORD PF04968.12 ORX88513.1 - 0.1 13.4 12.5 3.5 8.4 2.8 3.4 3 0 0 3 3 3 0 CHORD zf-C2H2_aberr PF17017.5 ORX88513.1 - 0.13 12.4 5.9 2.2 8.4 2.2 3.1 3 1 0 3 3 3 0 Aberrant zinc-finger INO80_Ies4 PF08193.11 ORX88513.1 - 2.4 8.1 11.6 4.5 7.2 11.6 1.5 1 1 0 1 1 1 0 INO80 complex subunit Ies4 B56 PF01603.20 ORX88514.1 - 4.4e-192 638.6 7.2 5.4e-192 638.3 7.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Gram_pos_anchor PF00746.21 ORX88515.1 - 0.39 10.7 4.5 0.72 9.9 3.8 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Pyrid_oxidase_2 PF13883.6 ORX88516.1 - 4.5e-33 114.6 0.0 5.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ORX88516.1 - 0.00033 20.8 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Arrestin_C PF02752.22 ORX88517.1 - 1e-11 45.4 0.2 3e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX88517.1 - 3.1e-08 33.8 0.1 1.1e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX88517.1 - 4e-05 23.4 0.0 6.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like p450 PF00067.22 ORX88518.1 - 1.2e-63 215.5 0.9 1.5e-53 182.2 0.0 2.5 1 1 1 2 2 2 2 Cytochrome P450 BAR PF03114.18 ORX88519.1 - 5.5e-42 144.0 0.5 6.5e-42 143.8 0.5 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 ORX88519.1 - 0.0064 16.1 1.2 0.11 12.1 1.4 2.6 1 1 1 2 2 2 1 Arfaptin-like domain DUF4455 PF14643.6 ORX88519.1 - 0.014 14.1 0.1 0.024 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) BAR_3 PF16746.5 ORX88519.1 - 0.045 13.5 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 BAR domain of APPL family RasGAP PF00616.19 ORX88520.1 - 0.00048 19.9 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Sel1 PF08238.12 ORX88520.1 - 0.0086 16.7 0.2 0.075 13.7 0.1 2.5 2 0 0 2 2 2 1 Sel1 repeat Clathrin-link PF09268.10 ORX88520.1 - 0.2 11.0 1.6 0.48 9.8 1.6 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker GPI-anchored PF10342.9 ORX88521.1 - 5.1e-08 33.6 0.1 6.4e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aromatic_hydrox PF11723.8 ORX88521.1 - 0.031 13.8 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase RRM_1 PF00076.22 ORX88522.1 - 1.2e-16 60.3 0.0 1.4e-10 40.8 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.22 ORX88523.1 - 6e-46 157.2 20.6 1.4e-44 152.7 20.6 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Isochorismatase PF00857.20 ORX88524.1 - 3e-19 69.9 0.0 6.3e-19 68.8 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family SKN1 PF03935.15 ORX88525.1 - 3.4e-171 570.0 9.1 2.3e-169 564.0 5.7 2.0 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Miga PF10265.9 ORX88525.1 - 0.011 14.8 5.1 0.014 14.4 5.1 1.1 1 0 0 1 1 1 0 Mitoguardin FAM199X PF15814.5 ORX88525.1 - 0.033 13.2 13.5 0.063 12.3 13.5 1.4 1 0 0 1 1 1 0 Protein family FAM199X Apt1 PF10351.9 ORX88525.1 - 0.18 10.6 7.5 0.25 10.2 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 ORX88525.1 - 0.35 8.9 12.5 0.5 8.4 12.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PI3K_1B_p101 PF10486.9 ORX88525.1 - 0.64 7.7 9.3 0.86 7.3 9.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1712 PF08217.11 ORX88525.1 - 1.1 7.6 4.4 1.4 7.3 4.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Macoilin PF09726.9 ORX88525.1 - 2.1 6.8 13.7 2.8 6.4 13.7 1.1 1 0 0 1 1 1 0 Macoilin family SKN1 PF03935.15 ORX88526.1 - 4.5e-171 569.6 8.7 2.2e-169 564.1 5.7 2.0 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Miga PF10265.9 ORX88526.1 - 0.011 14.8 4.6 0.014 14.4 4.6 1.1 1 0 0 1 1 1 0 Mitoguardin FAM199X PF15814.5 ORX88526.1 - 0.019 14.0 13.1 0.036 13.1 13.1 1.4 1 0 0 1 1 1 0 Protein family FAM199X Apt1 PF10351.9 ORX88526.1 - 0.14 11.0 6.8 0.18 10.6 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 ORX88526.1 - 0.51 8.1 9.1 0.7 7.6 9.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sporozoite_P67 PF05642.11 ORX88526.1 - 0.54 8.3 12.3 0.77 7.8 12.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1712 PF08217.11 ORX88526.1 - 1.8 6.9 4.3 2.3 6.6 4.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Macoilin PF09726.9 ORX88526.1 - 2.4 6.6 13.4 3.2 6.2 13.4 1.1 1 0 0 1 1 1 0 Macoilin family SKN1 PF03935.15 ORX88527.1 - 1.2e-171 571.6 7.5 1.4e-170 568.0 7.5 1.9 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Rab_eff_C PF04698.12 ORX88527.1 - 0.012 13.9 5.5 0.017 13.4 5.5 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus SR-25 PF10500.9 ORX88527.1 - 4.1 6.9 12.8 8 6.0 12.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cpn60_TCP1 PF00118.24 ORX88529.1 - 7.1e-163 542.7 11.0 8.1e-163 542.6 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF356 PF04009.12 ORX88529.1 - 0.016 15.4 0.1 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF356) PEPCK_N PF17297.2 ORX88529.1 - 0.047 13.3 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase N-terminal domain TetR_C_14 PF17754.1 ORX88529.1 - 0.073 13.0 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 MftR C-terminal domain COPIIcoated_ERV PF07970.12 ORX88530.1 - 7e-42 143.8 0.0 1.3e-41 142.9 0.0 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORX88530.1 - 2.6e-23 82.2 0.0 4.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ras PF00071.22 ORX88531.1 - 4.5e-62 208.4 0.4 5.4e-62 208.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX88531.1 - 7.1e-36 123.1 0.2 1.1e-35 122.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX88531.1 - 3.5e-13 49.4 0.1 4.6e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX88531.1 - 5.7e-08 32.8 0.1 1.1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX88531.1 - 7e-05 22.4 0.3 0.00031 20.4 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX88531.1 - 9.2e-05 22.4 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ORX88531.1 - 0.00017 21.9 0.0 0.0017 18.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 ORX88531.1 - 0.00073 19.0 0.1 0.0012 18.3 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 ORX88531.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 ORX88531.1 - 0.0095 16.3 0.1 0.017 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain GDP_Man_Dehyd PF16363.5 ORX88531.1 - 0.011 15.1 0.2 0.041 13.3 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ABC_tran PF00005.27 ORX88531.1 - 0.015 15.8 0.2 0.025 15.1 0.2 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 ORX88531.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FAD-SLDH PF12318.8 ORX88531.1 - 0.023 14.7 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_14 PF13173.6 ORX88531.1 - 0.028 14.5 0.1 0.066 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain MgpC PF05220.12 ORX88531.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 MgpC protein precursor FeoB_N PF02421.18 ORX88531.1 - 0.03 13.9 0.3 0.058 12.9 0.3 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 ORX88531.1 - 0.042 13.4 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORX88531.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ORX88531.1 - 0.068 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 ORX88531.1 - 0.13 12.0 0.9 0.23 11.2 0.7 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 ORX88531.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 ORX88531.1 - 0.15 11.9 0.4 0.42 10.5 0.4 1.7 1 1 1 2 2 2 0 NTPase DnaJ PF00226.31 ORX88532.1 - 1.5e-15 57.1 0.1 2.8e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3975 PF13126.6 ORX88532.1 - 0.13 12.7 1.0 0.33 11.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) Yip1 PF04893.17 ORX88532.1 - 0.13 12.0 7.9 0.05 13.3 4.3 1.9 2 0 0 2 2 2 0 Yip1 domain ABC_tran PF00005.27 ORX88534.1 - 4.6e-16 59.6 0.1 7.1e-15 55.7 0.1 2.3 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX88534.1 - 1.2e-09 38.4 2.9 0.00049 20.0 0.3 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORX88534.1 - 0.00091 18.9 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORX88534.1 - 0.0057 16.0 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 ORX88534.1 - 0.0068 16.9 0.9 0.02 15.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORX88534.1 - 0.0082 16.2 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ORX88534.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORX88534.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ORX88534.1 - 0.036 14.6 3.9 0.37 11.3 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORX88534.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 ORX88534.1 - 0.045 13.2 0.1 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX88534.1 - 0.045 14.1 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 ORX88534.1 - 0.045 13.2 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 ORX88534.1 - 0.046 14.1 0.0 0.3 11.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORX88534.1 - 0.05 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ORX88534.1 - 0.055 13.2 0.3 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORX88534.1 - 0.063 12.6 0.0 0.54 9.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_27 PF13514.6 ORX88534.1 - 0.068 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORX88534.1 - 0.1 11.7 0.2 0.2 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 ORX88534.1 - 0.28 9.8 0.9 0.55 8.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain FGGY_N PF00370.21 ORX88535.1 - 3.4e-24 85.7 0.0 4.5e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ORX88535.1 - 5.4e-16 58.9 0.0 3.8e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain LSM PF01423.22 ORX88536.1 - 1.7e-09 37.2 0.0 2.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX88536.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain zf-H2C2_2 PF13465.6 ORX88537.1 - 1.7e-21 75.6 21.5 8.1e-07 29.2 2.2 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX88537.1 - 1.1e-18 66.6 29.2 6.3e-05 23.2 3.6 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX88537.1 - 4.3e-11 42.7 26.1 0.0068 17.2 2.6 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX88537.1 - 5.7e-08 32.9 5.6 0.08 13.3 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX88537.1 - 8.2e-06 26.4 8.5 0.0086 16.7 0.2 3.7 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-met PF12874.7 ORX88537.1 - 0.00036 20.8 8.5 5 7.7 0.0 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX88537.1 - 0.007 16.6 8.4 3.6 7.9 0.4 3.0 1 1 0 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX88537.1 - 0.041 14.6 10.4 0.075 13.7 1.6 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger MCM_OB PF17207.3 ORX88537.1 - 5.1 7.0 6.3 21 5.0 0.7 2.5 1 1 1 2 2 2 0 MCM OB domain zf-C2H2_6 PF13912.6 ORX88537.1 - 8.6 6.5 16.6 3.8 7.6 1.8 4.2 4 2 0 4 4 4 0 C2H2-type zinc finger Cyclin_N PF00134.23 ORX88538.1 - 2.2e-13 50.0 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX88538.1 - 3.5e-10 40.5 0.0 4.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Acetyltransf_3 PF13302.7 ORX88539.1 - 5.5e-24 85.4 0.0 6.8e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX88539.1 - 7.3e-11 42.3 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ORX88539.1 - 1.3e-05 24.9 0.1 0.00016 21.4 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX88539.1 - 2.3e-05 24.3 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ORX88539.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX88539.1 - 0.0021 18.2 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORX88539.1 - 0.015 14.8 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_10 PF13673.7 ORX88539.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ESSS PF10183.9 ORX88540.1 - 2e-11 44.0 0.1 2.5e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Topoisom_bac PF01131.20 ORX88541.1 - 2.4e-111 372.7 0.0 3e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 ORX88541.1 - 2.3e-17 63.1 0.0 4.6e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Elf1 PF05129.13 ORX88541.1 - 2.2 8.4 6.0 10 6.2 0.4 3.2 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DUF5549 PF17703.1 ORX88541.1 - 3.3 7.3 5.0 5.9 6.5 5.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) AA_permease_2 PF13520.6 ORX88542.1 - 2.5e-28 99.1 11.1 2.5e-28 99.1 11.1 1.6 2 0 0 2 2 2 1 Amino acid permease DUF4131 PF13567.6 ORX88542.1 - 0.089 12.4 0.6 0.19 11.4 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 ORX88542.1 - 4.6 7.5 5.9 16 5.8 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) 6PGD PF00393.19 ORX88543.1 - 1.3e-75 254.4 0.0 1.5e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain Ribosomal_L38e PF01781.18 ORX88545.1 - 1.2e-35 121.4 1.7 1.3e-35 121.3 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORX88545.1 - 0.07 13.4 0.0 0.072 13.3 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORX88545.1 - 0.098 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Xpo1 PF08389.12 ORX88546.1 - 8.5e-14 51.9 3.5 4e-12 46.4 0.1 4.6 4 3 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 ORX88546.1 - 2.6e-07 30.4 0.0 1.3e-06 28.2 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DIM1 PF02966.16 ORX88547.1 - 2.3e-49 166.6 0.2 2.7e-49 166.4 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORX88547.1 - 0.00043 20.2 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Ribosomal_S9 PF00380.19 ORX88549.1 - 1e-44 151.9 0.1 1.6e-44 151.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HJURP_C PF12347.8 ORX88549.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat RNR_inhib PF08591.10 ORX88551.1 - 5.6e-06 27.6 0.1 7.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor RNase_P_Rpp14 PF01900.19 ORX88552.1 - 3.8e-34 117.0 0.0 4.9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SHMT PF00464.19 ORX88553.1 - 4.1e-206 684.2 0.0 4.8e-206 684.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 ORX88553.1 - 0.061 12.6 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 ORX88554.1 - 4.1e-206 684.2 0.0 4.8e-206 684.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 ORX88554.1 - 0.061 12.6 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SRF-TF PF00319.18 ORX88555.1 - 1.7e-16 59.4 0.2 2.9e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AGTRAP PF06396.11 ORX88556.1 - 0.00027 20.8 0.5 0.00045 20.1 0.5 1.5 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Thioredoxin PF00085.20 ORX88557.1 - 1.3e-22 79.7 0.0 1.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORX88557.1 - 0.015 15.7 0.2 0.037 14.5 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 ORX88557.1 - 0.017 14.9 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 ORX88557.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.20 ORX88558.1 - 6.5e-21 74.3 0.0 7.5e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 ORX88558.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glyco_hydro_18 PF00704.28 ORX88559.1 - 1.6e-76 258.1 5.5 1.6e-76 258.1 5.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX88559.1 - 0.016 15.8 8.9 0.016 15.8 8.9 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain DUF3439 PF11921.8 ORX88559.1 - 1 9.3 7.3 2.3 8.2 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 ORX88560.1 - 1.3e-76 258.3 5.2 1.3e-76 258.3 5.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX88560.1 - 0.016 15.8 8.9 0.016 15.8 8.9 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain DUF3439 PF11921.8 ORX88560.1 - 0.78 9.7 8.2 1.8 8.5 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 ORX88561.1 - 1.1e-76 258.6 5.6 1.1e-76 258.6 5.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX88561.1 - 0.001 19.5 8.6 0.001 19.5 8.6 2.7 2 0 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX88561.1 - 0.0086 16.0 6.0 0.0086 16.0 6.0 2.5 2 0 0 2 2 2 1 Cellulose-binding domain DUF3439 PF11921.8 ORX88561.1 - 0.75 9.8 8.4 1.7 8.6 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 ORX88562.1 - 1.1e-76 258.6 5.6 1.1e-76 258.6 5.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX88562.1 - 0.037 14.6 8.0 0.037 14.6 8.0 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain DUF3439 PF11921.8 ORX88562.1 - 0.79 9.7 8.2 1.8 8.5 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_4 PF13894.6 ORX88563.1 - 4.8e-14 51.8 12.1 8.4e-05 23.1 1.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX88563.1 - 4.5e-13 48.9 15.2 0.00028 21.2 2.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX88563.1 - 8.6e-13 48.1 11.3 7.8e-08 32.4 0.2 3.4 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX88563.1 - 6.4e-06 26.3 0.7 0.51 10.7 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX88563.1 - 3.9e-05 23.5 8.1 0.07 13.2 0.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 ORX88563.1 - 0.00017 21.6 3.0 0.028 14.5 0.2 2.6 3 0 0 3 3 3 2 Zinc ribbon domain zf_UBZ PF18439.1 ORX88563.1 - 0.00072 19.1 1.2 0.065 12.8 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf_ZIC PF18366.1 ORX88563.1 - 0.0013 18.8 4.3 0.29 11.3 0.1 2.8 1 1 2 3 3 3 2 Zic proteins zinc finger domain YhfH PF14149.6 ORX88563.1 - 0.0042 17.0 0.2 0.96 9.5 0.0 2.3 2 0 0 2 2 2 1 YhfH-like protein zf-C2H2_11 PF16622.5 ORX88563.1 - 0.0049 16.6 11.6 0.21 11.4 0.2 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORX88563.1 - 0.013 15.3 0.5 0.013 15.3 0.5 3.2 4 1 0 4 4 3 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 ORX88563.1 - 0.016 15.1 4.4 2.6 8.0 0.9 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-CHY PF05495.12 ORX88563.1 - 0.027 14.9 1.2 0.039 14.4 1.0 1.5 1 1 0 1 1 1 0 CHY zinc finger zf-C2HE PF16278.5 ORX88563.1 - 0.028 14.9 6.5 0.22 12.0 0.4 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 ORX88563.1 - 0.038 14.3 1.5 0.06 13.6 0.5 1.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 ORX88563.1 - 0.087 13.5 2.0 0.28 11.8 0.6 2.1 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORX88563.1 - 0.1 13.1 1.2 32 5.1 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORX88563.1 - 0.1 12.9 2.2 17 5.8 0.0 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 ORX88563.1 - 0.14 11.8 1.6 0.27 10.9 0.2 2.1 2 1 1 3 3 3 0 MYST family zinc finger domain HypA PF01155.19 ORX88563.1 - 0.19 11.8 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 ORX88563.1 - 0.27 11.2 3.0 2.4 8.2 0.6 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 ORX88563.1 - 0.45 10.5 5.0 1.7 8.7 2.0 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 ORX88563.1 - 0.46 10.4 5.9 2.5 8.1 0.8 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-AN1 PF01428.16 ORX88563.1 - 0.64 10.2 10.7 8.2 6.7 4.9 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger Dynamin_M PF01031.20 ORX88564.1 - 7e-106 353.6 0.1 7e-106 353.6 0.1 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORX88564.1 - 5.6e-56 189.2 0.1 1.2e-55 188.1 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORX88564.1 - 6.6e-30 103.1 7.5 6.6e-30 103.1 7.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORX88564.1 - 1.8e-05 24.8 1.0 0.0013 18.8 1.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ORX88564.1 - 0.00011 22.1 4.6 2.2 7.9 0.2 3.3 2 1 1 3 3 3 3 AAA ATPase domain AAA_16 PF13191.6 ORX88564.1 - 0.08 13.3 0.2 0.4 11.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Strep_SA_rep PF06696.11 ORX88564.1 - 0.15 12.1 4.9 0.4 10.7 4.9 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Sec7_N PF12783.7 ORX88564.1 - 0.27 11.1 6.9 1.3 8.9 0.1 3.7 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal F-box_4 PF15966.5 ORX88565.1 - 4.7e-07 29.7 0.6 2.5e-06 27.4 0.5 2.1 2 0 0 2 2 2 1 F-box SMI1_KNR4 PF09346.10 ORX88565.1 - 0.00031 21.1 0.0 0.00053 20.4 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 ORX88565.1 - 0.00096 18.9 0.0 0.0051 16.6 0.0 2.1 3 0 0 3 3 3 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 ORX88565.1 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.8 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall F-box-like PF12937.7 ORX88565.1 - 0.0028 17.5 0.1 0.0059 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX88565.1 - 0.021 14.7 0.9 0.039 13.9 0.2 1.9 2 0 0 2 2 2 0 F-box domain Leptin PF02024.15 ORX88565.1 - 0.025 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Leptin LOB PF03195.14 ORX88565.1 - 0.086 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Lateral organ boundaries (LOB) domain FHA PF00498.26 ORX88566.1 - 9.4e-19 67.5 0.3 2.2e-18 66.4 0.3 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 ORX88566.1 - 1.2e-09 38.3 9.3 2.7e-09 37.2 9.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX88566.1 - 3.4e-09 36.4 7.4 8.1e-09 35.2 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX88566.1 - 7.7e-09 35.3 7.3 1.7e-08 34.2 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX88566.1 - 6.5e-08 32.3 4.5 1.2e-07 31.4 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 ORX88566.1 - 5.7e-06 26.6 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 ORX88566.1 - 3.8e-05 23.6 8.1 0.00018 21.4 8.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX88566.1 - 5.9e-05 23.0 8.2 0.00016 21.7 8.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORX88566.1 - 9.2e-05 22.2 9.7 9.2e-05 22.2 9.7 2.6 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORX88566.1 - 0.00017 21.7 9.9 0.00038 20.6 9.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 ORX88566.1 - 0.00061 19.8 3.8 0.0011 18.9 3.8 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 ORX88566.1 - 0.0021 17.9 3.1 0.004 17.0 3.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORX88566.1 - 0.0045 17.2 9.3 0.02 15.2 9.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX88566.1 - 0.0066 16.5 1.5 0.016 15.2 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORX88566.1 - 0.01 15.5 6.5 0.018 14.7 6.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FYVE PF01363.21 ORX88566.1 - 0.13 12.5 7.5 2.5 8.3 0.1 2.6 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.7 ORX88566.1 - 0.13 12.3 4.0 0.37 10.9 4.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 ORX88566.1 - 0.38 10.6 7.6 1.6 8.6 7.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 ORX88566.1 - 0.71 10.1 3.3 1.6 8.9 3.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 ORX88566.1 - 0.76 9.6 7.1 2 8.3 7.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 ORX88567.1 - 1.4e-25 90.1 0.0 1.9e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88567.1 - 1.3e-10 41.0 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX88567.1 - 2.4e-07 29.9 0.7 3.6e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Ribonuc_P_40 PF08584.11 ORX88567.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Big_5 PF13205.6 ORX88570.1 - 0.0043 17.7 2.5 0.0093 16.7 0.3 2.7 3 0 0 3 3 3 1 Bacterial Ig-like domain L6_membrane PF05805.12 ORX88570.1 - 0.0065 16.1 0.3 0.26 10.8 0.0 2.5 2 0 0 2 2 2 1 L6 membrane protein DUF1475 PF07343.11 ORX88570.1 - 0.084 12.7 4.0 0.18 11.6 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) Phage_holin_2_1 PF04971.12 ORX88570.1 - 0.11 12.5 0.7 0.49 10.4 0.7 2.1 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF4448 PF14610.6 ORX88571.1 - 0.002 17.9 0.4 0.031 14.1 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) Shisa PF13908.6 ORX88571.1 - 0.12 12.6 0.4 0.23 11.7 0.3 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Mito_carr PF00153.27 ORX88572.1 - 5.4e-75 247.4 0.6 8.6e-26 89.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 ORX88572.1 - 0.052 13.7 0.1 18 5.6 0.0 2.8 3 0 0 3 3 3 0 PrcB C-terminal GAD-like PF08887.11 ORX88572.1 - 0.092 12.5 0.6 1.7 8.4 0.0 2.9 3 1 0 3 3 3 0 GAD-like domain Trypsin PF00089.26 ORX88573.1 - 1.1e-41 143.1 0.1 1.3e-41 142.8 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX88573.1 - 1.1e-08 36.2 0.0 1.6e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 ORX88573.1 - 0.0046 17.3 0.0 0.0086 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Nucleos_tra2_C PF07662.13 ORX88574.1 - 1.2e-73 247.4 7.4 1.2e-73 247.4 7.4 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX88574.1 - 9.2e-24 83.8 4.2 9.2e-24 83.8 4.2 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX88574.1 - 0.006 16.9 8.9 0.006 16.9 8.9 4.2 3 2 0 3 3 3 1 Nucleoside recognition Lipase_3 PF01764.25 ORX88575.1 - 2.5e-33 114.9 0.0 4.1e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX88575.1 - 0.00044 19.9 0.4 0.0026 17.4 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX88575.1 - 0.0028 18.3 0.0 0.0038 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ox_reductase_C PF08635.10 ORX88575.1 - 0.058 13.1 0.1 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain SgrT PF15894.5 ORX88575.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Lipase_3 PF01764.25 ORX88576.1 - 1.2e-32 112.8 0.0 1.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX88576.1 - 0.00094 19.8 0.0 0.0012 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORX88576.1 - 0.0019 17.8 0.8 0.014 15.0 0.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) ox_reductase_C PF08635.10 ORX88576.1 - 0.059 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Abhydrolase_1 PF00561.20 ORX88578.1 - 3.7e-51 174.2 0.0 4.5e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX88578.1 - 0.024 15.3 0.0 0.036 14.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Prenyltrans PF00432.21 ORX88579.1 - 5.9e-26 89.9 4.2 3.1e-05 23.6 0.0 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat PAP_assoc PF03828.19 ORX88580.1 - 7.9e-15 54.8 0.0 7.5e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORX88580.1 - 0.084 13.2 0.0 0.26 11.6 0.0 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase domain OHCU_decarbox PF09349.10 ORX88581.1 - 6.2e-45 153.4 0.1 7.1e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase TauD PF02668.16 ORX88581.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DUF2527 PF10736.9 ORX88581.1 - 0.27 11.1 0.8 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) WD40 PF00400.32 ORX88582.1 - 1.6e-13 50.9 6.6 7.8e-05 23.4 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat GPI-anchored PF10342.9 ORX88583.1 - 9.3e-16 58.4 0.1 9.3e-16 58.4 0.1 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fz PF01392.22 ORX88585.1 - 0.063 13.9 0.6 0.13 12.9 0.4 1.6 1 1 0 1 1 1 0 Fz domain Hamartin PF04388.12 ORX88585.1 - 0.9 8.1 11.9 1.2 7.7 11.9 1.1 1 0 0 1 1 1 0 Hamartin protein Speriolin_N PF15058.6 ORX88585.1 - 1.2 9.2 12.5 1.8 8.6 12.5 1.2 1 0 0 1 1 1 0 Speriolin N terminus PX PF00787.24 ORX88587.1 - 1.4e-06 28.2 1.1 2.4e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 PX domain WD40 PF00400.32 ORX88588.1 - 2.3e-49 164.3 22.8 4.9e-08 33.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX88588.1 - 1.5e-12 47.7 1.8 0.019 15.2 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX88588.1 - 8.9e-05 21.6 0.1 0.62 9.0 0.0 4.1 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORX88588.1 - 0.00052 19.9 0.1 0.03 14.2 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORX88588.1 - 0.0016 17.2 7.2 0.025 13.3 0.2 4.5 3 2 3 7 7 7 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORX88588.1 - 0.0093 14.5 0.1 2.7 6.4 0.1 2.7 2 2 1 3 3 3 2 Cytochrome D1 heme domain DUF1513 PF07433.11 ORX88588.1 - 0.011 14.9 0.0 0.53 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.12 ORX88588.1 - 0.3 11.1 1.5 38 4.4 0.1 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Fasciclin PF02469.22 ORX88589.1 - 1.3e-13 51.2 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Pkinase PF00069.25 ORX88590.1 - 2.9e-70 236.7 0.0 4.3e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88590.1 - 1.6e-41 142.3 0.0 2.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORX88590.1 - 1.6e-15 56.6 0.1 3e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORX88590.1 - 2.8e-07 30.2 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX88590.1 - 6.6e-05 22.0 0.1 6.6e-05 22.0 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORX88590.1 - 0.0077 16.2 0.5 0.036 14.0 0.1 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX88590.1 - 0.016 14.6 0.2 0.016 14.6 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX88590.1 - 0.069 11.9 0.0 0.069 11.9 0.0 2.6 2 1 0 2 2 1 0 Fungal protein kinase RIO1 PF01163.22 ORX88590.1 - 0.16 11.6 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Flu_M2 PF00599.17 ORX88590.1 - 0.19 11.8 0.2 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Influenza Matrix protein (M2) MRP-63 PF14978.6 ORX88590.1 - 1.8 9.2 10.4 2.8 8.6 0.1 3.5 2 1 1 3 3 3 0 Mitochondrial ribosome protein 63 zf-H2C2_2 PF13465.6 ORX88591.1 - 4.4e-08 33.2 1.1 4.4e-08 33.2 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX88591.1 - 1.7e-07 31.4 11.6 0.00076 20.1 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX88591.1 - 4.5e-06 26.8 13.3 0.0016 18.7 2.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORX88591.1 - 7.8e-05 22.8 7.3 0.0099 16.1 1.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX88591.1 - 0.00015 22.0 4.6 0.017 15.4 1.6 2.1 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.14 ORX88591.1 - 0.0015 18.4 1.8 0.97 9.4 0.1 2.1 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-LYAR PF08790.11 ORX88591.1 - 0.0042 17.0 5.8 0.22 11.5 0.6 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger Ephrin_rec_like PF07699.13 ORX88591.1 - 0.012 15.3 0.9 0.091 12.5 0.2 2.1 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-C2H2_2 PF12756.7 ORX88591.1 - 0.015 15.6 5.9 0.59 10.5 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX88591.1 - 0.026 14.3 13.1 0.16 11.7 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DUF2180 PF09947.9 ORX88591.1 - 0.032 14.2 0.2 0.039 13.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zinc_ribbon_9 PF14369.6 ORX88591.1 - 0.12 12.6 2.9 0.31 11.3 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_3rep PF18868.1 ORX88591.1 - 0.19 12.4 3.7 2.6 8.7 3.2 2.0 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 ORX88591.1 - 0.84 8.1 7.4 0.16 10.5 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 ORX88591.1 - 1.1 8.9 7.5 4.9 6.9 0.7 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Actin_micro PF17003.5 ORX88591.1 - 6.6 5.8 6.0 76 2.3 6.0 1.9 1 1 0 1 1 1 0 Putative actin-like family Asn_synthase PF00733.21 ORX88592.1 - 2.2e-67 228.2 0.0 3.4e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORX88592.1 - 2.5e-42 143.7 0.0 4.3e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX88592.1 - 5.8e-34 117.2 0.0 1.1e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 ORX88592.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 ORX88592.1 - 0.017 14.6 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein Asn_synthase PF00733.21 ORX88593.1 - 5.5e-71 240.1 0.0 7.5e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORX88593.1 - 4.4e-43 146.1 0.0 6.9e-43 145.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX88593.1 - 3.2e-33 114.8 0.0 6.5e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 ORX88593.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 ORX88593.1 - 0.0043 16.5 0.0 0.0095 15.4 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein Asn_synthase PF00733.21 ORX88594.1 - 4.2e-66 224.0 0.0 6.3e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORX88594.1 - 2.2e-42 143.8 0.0 3.7e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX88594.1 - 3.4e-34 117.9 0.0 6.2e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 ORX88594.1 - 0.0085 15.2 0.0 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 NAD synthase DUF3700 PF12481.8 ORX88594.1 - 0.016 14.7 0.0 0.041 13.3 0.0 1.6 2 0 0 2 2 2 0 Aluminium induced protein Asn_synthase PF00733.21 ORX88595.1 - 9.1e-67 226.2 0.0 1.4e-66 225.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORX88595.1 - 2.9e-42 143.5 0.0 4.4e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX88595.1 - 6e-34 117.1 0.0 1.1e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORX88595.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.6 2 0 0 2 2 2 0 Aluminium induced protein NAD_synthase PF02540.17 ORX88595.1 - 0.048 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Asn_synthase PF00733.21 ORX88596.1 - 5.1e-67 227.0 0.0 7.6e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ORX88596.1 - 2.5e-42 143.7 0.0 3.8e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX88596.1 - 3.5e-34 117.9 0.0 6.3e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 ORX88596.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF3700 PF12481.8 ORX88596.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein Trypsin PF00089.26 ORX88600.1 - 8.7e-13 48.6 0.7 2.4e-12 47.1 0.7 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX88600.1 - 0.0079 17.1 0.2 0.26 12.2 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain Glyco_hydro_32N PF00251.20 ORX88601.1 - 4.3e-49 167.7 3.0 7.7e-49 166.9 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORX88601.1 - 2.7e-24 86.0 1.6 6e-24 84.8 1.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 ORX88601.1 - 6.3e-06 26.4 1.4 1.3e-05 25.4 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR_2 PF13088.6 ORX88601.1 - 0.013 14.8 2.2 0.51 9.6 0.9 3.1 2 1 1 3 3 3 0 BNR repeat-like domain NmrA PF05368.13 ORX88602.1 - 4.6e-41 140.9 0.0 5.8e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX88602.1 - 9e-22 77.8 0.0 1.5e-21 77.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX88602.1 - 8.1e-09 35.3 0.1 6.4e-05 22.5 0.0 3.1 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX88602.1 - 0.0002 20.5 0.0 0.00047 19.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORX88602.1 - 0.00037 20.9 0.0 0.0026 18.2 0.0 2.3 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORX88602.1 - 0.00085 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 ORX88602.1 - 0.017 15.2 0.1 0.038 14.1 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 ORX88602.1 - 0.022 14.1 0.0 1.6 8.0 0.0 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORX88602.1 - 0.036 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein SIS_2 PF13580.6 ORX88603.1 - 5.1e-12 46.0 0.0 1.4e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS PF01380.22 ORX88603.1 - 3.5e-11 43.1 2.1 4e-10 39.7 0.2 2.4 2 0 0 2 2 2 1 SIS domain ANTAR PF03861.14 ORX88603.1 - 0.017 14.9 0.1 0.05 13.4 0.1 1.7 1 0 0 1 1 1 0 ANTAR domain UBA_4 PF14555.6 ORX88603.1 - 0.045 13.6 0.1 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 UBA-like domain XRCC4 PF06632.12 ORX88604.1 - 3.2e-07 29.5 15.0 1e-06 27.9 14.9 1.9 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 TLE_N PF03920.15 ORX88604.1 - 0.02 14.9 0.1 0.15 12.1 0.8 2.0 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Nuc_N PF14448.6 ORX88604.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Nuclease N terminal Arf PF00025.21 ORX88605.1 - 8.6e-49 165.3 0.0 1e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORX88605.1 - 7.2e-14 51.7 0.0 9.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX88605.1 - 6.6e-13 48.9 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORX88605.1 - 1.1e-11 44.5 0.1 1.2e-08 34.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORX88605.1 - 6e-11 42.1 0.0 7.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORX88605.1 - 6.4e-10 38.9 0.1 3.9e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX88605.1 - 6e-09 36.0 0.0 8.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX88605.1 - 3.7e-08 33.0 0.0 4.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 ORX88605.1 - 0.0092 16.5 0.1 0.013 16.0 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX88605.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 ORX88605.1 - 0.018 14.0 0.1 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 ORX88605.1 - 0.022 14.5 0.1 4.9 6.9 0.0 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ORX88605.1 - 0.022 14.7 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 ORX88605.1 - 0.035 13.9 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ORX88605.1 - 0.099 13.2 0.0 0.19 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 ORX88605.1 - 0.1 12.2 0.2 13 5.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ORX88605.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 ORX88605.1 - 0.13 11.8 0.7 0.81 9.2 0.7 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B Thymidylate_kin PF02223.17 ORX88605.1 - 0.19 11.4 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase Peptidase_C12 PF01088.21 ORX88606.1 - 7.1e-66 222.0 0.0 8.2e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AhpC-TSA PF00578.21 ORX88607.1 - 4.1e-31 107.5 0.0 6.1e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORX88607.1 - 7.1e-14 51.4 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORX88607.1 - 8.4e-13 48.3 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.19 ORX88607.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Zn_dep_PLPC PF00882.18 ORX88607.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C PAS_3 PF08447.12 ORX88608.1 - 1.4e-07 31.7 0.0 1.4e-06 28.5 0.0 2.4 2 1 0 2 2 2 1 PAS fold PAS PF00989.25 ORX88608.1 - 2.6e-05 24.2 0.0 9.8e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORX88608.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain AhpC-TSA PF00578.21 ORX88609.1 - 4.1e-31 107.5 0.0 6.1e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORX88609.1 - 7.1e-14 51.4 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORX88609.1 - 8.4e-13 48.3 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin GSHPx PF00255.19 ORX88609.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Zn_dep_PLPC PF00882.18 ORX88609.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C DUF21 PF01595.20 ORX88610.1 - 5.4e-40 136.9 0.1 8.6e-40 136.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORX88610.1 - 9e-09 35.7 0.1 0.0001 22.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain Fumarate_red_D PF02313.17 ORX88610.1 - 0.52 10.4 8.8 0.051 13.7 3.4 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit D SNF2_N PF00176.23 ORX88611.1 - 1.4e-64 218.0 1.7 1.4e-64 218.0 1.7 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 ORX88611.1 - 4.6e-48 163.0 17.3 4.6e-48 163.0 17.3 4.0 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 ORX88611.1 - 1.5e-17 63.9 2.5 1.9e-16 60.4 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX88611.1 - 2.3e-06 27.7 0.2 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HAD PF12710.7 ORX88612.1 - 2.2e-10 41.2 0.0 1.2e-09 38.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORX88612.1 - 0.00021 20.9 0.0 0.028 14.0 0.0 2.9 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 ORX88612.1 - 0.00096 18.6 0.0 1.3 8.3 0.0 2.8 2 1 0 2 2 2 2 Putative Phosphatase Hydrolase_3 PF08282.12 ORX88612.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PTPLA PF04387.14 ORX88613.1 - 3.2e-49 166.8 14.4 3.2e-49 166.8 14.4 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA muHD PF10291.9 ORX88614.1 - 1.1e-49 169.2 0.0 1.8e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain zf-RRN7 PF11781.8 ORX88615.1 - 0.0001 21.9 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C3HC4_5 PF17121.5 ORX88615.1 - 0.0015 18.4 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RPA_interact_C PF14768.6 ORX88615.1 - 0.046 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Lactamase_B PF00753.27 ORX88616.1 - 2e-13 50.8 0.2 1.5e-05 25.1 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily TPR_1 PF00515.28 ORX88616.1 - 5.2e-05 22.9 12.8 0.07 13.0 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX88616.1 - 0.0001 22.1 11.2 0.16 12.2 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX88616.1 - 0.02 14.9 3.3 1.6 8.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 ORX88616.1 - 0.035 13.6 0.1 0.13 11.7 0.1 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF3856 PF12968.7 ORX88616.1 - 0.15 12.1 0.8 0.32 11.1 0.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 ORX88616.1 - 0.62 10.4 7.2 5.4 7.4 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 ORX88616.1 - 1.5 8.9 7.2 10 6.3 0.5 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 ORX88616.1 - 8.5 7.1 7.9 23 5.8 0.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat SF3A2 PF16835.5 ORX88617.1 - 8.3e-40 135.1 0.1 1.3e-39 134.5 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 ORX88617.1 - 4.4e-07 30.1 1.7 4.4e-07 30.1 1.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 ORX88617.1 - 3.7e-05 23.6 0.8 5.8e-05 23.0 0.8 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 ORX88617.1 - 0.017 14.6 0.9 0.03 13.9 0.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like FH2 PF02181.23 ORX88618.1 - 1.1e-90 304.5 7.3 1.1e-90 304.5 7.3 2.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORX88618.1 - 4.8e-45 153.4 0.5 4.8e-45 153.4 0.5 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORX88618.1 - 1.2e-32 113.1 0.0 4.3e-32 111.3 0.0 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain RasGAP PF00616.19 ORX88618.1 - 0.041 13.6 1.6 0.17 11.6 1.6 2.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Syntaxin_2 PF14523.6 ORX88618.1 - 0.062 13.7 2.3 1.4 9.4 0.1 3.2 2 0 0 2 2 2 0 Syntaxin-like protein DUF4407 PF14362.6 ORX88618.1 - 0.61 9.4 7.3 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 ORX88618.1 - 2.5 8.2 7.5 1.1 9.4 0.4 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation SET PF00856.28 ORX88619.1 - 3.4e-14 53.6 0.0 6.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 ORX88619.1 - 0.00087 20.0 0.7 0.0029 18.3 0.6 1.9 1 1 1 2 2 2 1 Rubisco LSMT substrate-binding DUF4262 PF14081.6 ORX88619.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) STIMATE PF12400.8 ORX88620.1 - 2.3e-37 128.3 6.2 3.3e-37 127.8 6.2 1.2 1 0 0 1 1 1 1 STIMATE family CLLAC PF15675.5 ORX88620.1 - 0.023 14.2 1.8 0.08 12.5 1.8 2.0 1 0 0 1 1 1 0 CLLAC-motif containing domain zf-C2H2 PF00096.26 ORX88621.1 - 2.5e-15 56.0 14.8 6.2e-05 23.2 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX88621.1 - 2.9e-10 40.1 15.4 0.0015 19.2 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX88621.1 - 5.7e-07 29.7 12.9 0.00043 20.6 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORX88621.1 - 0.00028 21.1 2.8 0.00028 21.1 2.8 2.4 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX88621.1 - 0.0021 17.8 2.6 0.75 9.6 0.1 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORX88621.1 - 0.003 17.5 16.1 0.28 11.3 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX88621.1 - 0.023 14.4 3.0 0.023 14.4 3.0 3.3 3 2 0 3 3 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORX88621.1 - 0.069 13.5 9.5 1.7 9.0 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 ORX88621.1 - 0.097 12.8 6.0 3.5 7.9 1.5 3.1 2 1 0 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 ORX88621.1 - 1 9.5 4.3 1.4 9.1 0.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 ORX88621.1 - 1.1 9.5 6.0 2.1 8.6 2.9 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.15 ORX88621.1 - 1.9 8.6 10.2 0.27 11.3 1.1 3.0 3 0 0 3 3 3 0 BED zinc finger zf-met PF12874.7 ORX88621.1 - 2.8 8.4 9.6 1.2 9.6 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORX88621.1 - 3.4 8.2 13.5 3.6 8.1 2.9 4.0 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger Aldo_ket_red PF00248.21 ORX88622.1 - 6.9e-52 176.5 0.0 8.5e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.20 ORX88625.1 - 2.6e-68 230.1 27.4 3.3e-68 229.8 27.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Cyclin_N PF00134.23 ORX88626.1 - 7.4e-11 41.9 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX88626.1 - 2.4e-08 34.5 0.2 2.9e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin DUF5106 PF17127.4 ORX88626.1 - 0.029 14.7 0.2 0.044 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) MtrF PF09472.10 ORX88626.1 - 0.039 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3687 PF12459.8 ORX88626.1 - 0.15 11.6 0.9 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Xan_ur_permease PF00860.20 ORX88628.1 - 1.1e-32 113.2 32.2 4.4e-31 107.9 32.2 2.1 1 1 0 1 1 1 1 Permease family ArsR PF09824.9 ORX88630.1 - 0.034 13.7 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Glu_cys_ligase PF04262.14 ORX88632.1 - 0.036 12.7 0.1 0.05 12.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase ABC2_membrane PF01061.24 ORX88633.1 - 1.3e-88 295.9 59.6 2.3e-49 167.7 24.4 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORX88633.1 - 1e-38 132.9 0.0 5.4e-19 69.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORX88633.1 - 8.2e-32 109.0 1.2 1.1e-22 79.7 0.1 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX88633.1 - 2.6e-11 44.0 0.0 1e-10 42.0 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORX88633.1 - 3.6e-09 36.2 48.2 8.9e-06 25.0 19.3 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORX88633.1 - 4.2e-07 30.1 0.1 0.0067 16.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORX88633.1 - 9.5e-07 28.9 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORX88633.1 - 7.6e-05 23.2 0.0 0.038 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORX88633.1 - 9.3e-05 22.1 0.0 0.01 15.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORX88633.1 - 9.7e-05 22.0 0.0 0.001 18.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX88633.1 - 0.00011 22.7 0.0 0.085 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX88633.1 - 0.00072 19.8 0.0 0.75 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORX88633.1 - 0.00097 19.2 0.2 0.88 9.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 ORX88633.1 - 0.0069 16.1 0.1 1.3 8.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX88633.1 - 0.0069 16.6 0.0 0.55 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORX88633.1 - 0.023 14.9 0.3 0.29 11.4 0.3 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORX88633.1 - 0.026 14.4 0.7 2.5 8.0 0.4 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 ORX88633.1 - 0.028 14.0 0.1 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORX88633.1 - 0.062 12.6 0.0 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 ORX88633.1 - 0.068 12.9 0.2 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ploopntkinase3 PF18751.1 ORX88633.1 - 0.084 12.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 ORX88633.1 - 0.18 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Citrate_synt PF00285.21 ORX88634.1 - 5.3e-104 348.2 0.0 6.6e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain LSM PF01423.22 ORX88635.1 - 4.4e-17 61.5 0.1 5.9e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain adh_short PF00106.25 ORX88638.1 - 7.5e-31 107.1 0.0 4.5e-23 81.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX88638.1 - 4.9e-22 78.6 0.0 8.8e-21 74.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX88638.1 - 9.4e-10 38.7 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX88638.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORX88638.1 - 0.0078 16.3 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORX88638.1 - 0.028 14.9 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PA PF02225.22 ORX88638.1 - 0.039 14.0 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 PA domain Lig_chan PF00060.26 ORX88643.1 - 0.18 11.6 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel LYRIC PF15686.5 ORX88644.1 - 0.013 15.1 0.8 0.015 14.9 0.8 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family VasI PF11319.8 ORX88644.1 - 0.27 10.9 2.7 3 7.4 2.5 2.0 1 1 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Pox_RNA_Pol_19 PF05320.12 ORX88651.1 - 0.83 9.6 3.5 0.77 9.7 2.3 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit LYRIC PF15686.5 ORX88652.1 - 0.058 13.0 0.6 0.066 12.8 0.6 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Pox_RNA_Pol_19 PF05320.12 ORX88656.1 - 0.36 10.8 3.2 0.38 10.7 2.4 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Velvet PF11754.8 ORX88658.1 - 8.5e-60 202.8 0.8 1.3e-38 133.4 0.3 2.0 1 1 1 2 2 2 2 Velvet factor Cyclin_C_2 PF16899.5 ORX88658.1 - 0.09 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin C-terminal domain MMADHC PF10229.9 ORX88659.1 - 1.3e-25 90.7 0.0 1.5e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein GATA PF00320.27 ORX88660.1 - 1.7e-30 104.3 17.6 3.9e-16 58.4 3.3 2.8 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX88660.1 - 8.3e-10 38.0 6.8 8.7e-05 22.0 0.1 2.8 2 1 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORX88660.1 - 8e-05 22.7 4.4 0.14 12.3 0.3 2.6 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.18 ORX88660.1 - 0.00056 20.0 8.6 0.01 15.9 1.0 2.6 2 1 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 ORX88660.1 - 0.00064 19.8 7.2 0.2 11.8 0.1 3.5 3 0 0 3 3 3 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 ORX88660.1 - 0.0068 16.3 11.8 0.1 12.5 1.8 2.8 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-RRN7 PF11781.8 ORX88660.1 - 0.017 14.8 0.6 0.017 14.8 0.6 3.7 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 ORX88660.1 - 0.055 13.4 5.7 0.4 10.6 0.5 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.6 ORX88660.1 - 0.18 11.3 13.0 6.7 6.3 0.1 4.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-piccolo PF05715.13 ORX88660.1 - 0.76 10.0 14.8 4.1 7.6 0.1 4.6 2 2 2 4 4 4 0 Piccolo Zn-finger Prim_Zn_Ribbon PF08273.12 ORX88660.1 - 1.5 9.2 21.9 9.8 6.6 6.2 4.4 2 2 2 4 4 4 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.10 ORX88660.1 - 7.5 6.4 16.1 1.5 8.6 1.8 4.1 3 1 0 3 3 3 0 A2L zinc ribbon domain Fungal_trans PF04082.18 ORX88661.1 - 1.2e-27 96.6 0.0 2.4e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX88661.1 - 1.3e-12 47.7 6.5 2.3e-12 46.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX88662.1 - 2.1e-28 99.1 0.0 3.7e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Coatomer_WDAD PF04053.14 ORX88663.1 - 2.9e-169 563.8 0.0 5.2e-169 563.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 ORX88663.1 - 1e-37 127.5 11.5 9.4e-07 29.4 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX88663.1 - 2e-05 24.8 1.1 5.5 7.3 0.0 5.8 4 3 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORX88663.1 - 0.0075 16.3 0.0 15 5.7 0.0 4.2 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 ORX88663.1 - 0.015 15.5 0.6 0.13 12.5 0.2 2.5 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Ge1_WD40 PF16529.5 ORX88663.1 - 0.028 13.4 2.0 1.1 8.2 0.0 3.0 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFA2_Winged_2 PF18121.1 ORX88664.1 - 1.7e-19 69.2 0.2 3.5e-19 68.2 0.2 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 ORX88664.1 - 6.3e-13 48.8 0.3 1.8e-12 47.3 0.3 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain RPA_C PF08784.11 ORX88664.1 - 0.047 14.4 0.1 0.16 12.7 0.1 1.8 1 1 1 2 2 2 0 Replication protein A C terminal Ribosomal_L19e PF01280.20 ORX88665.1 - 1.2e-64 216.7 10.3 1.2e-64 216.7 10.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e ABC_membrane PF00664.23 ORX88666.1 - 1e-98 330.4 24.7 2.8e-50 171.5 4.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORX88666.1 - 2.7e-69 232.0 0.2 5.1e-34 117.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX88666.1 - 5.4e-13 48.9 3.7 0.00067 19.1 0.5 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX88666.1 - 8.7e-08 31.8 0.4 0.0091 15.7 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORX88666.1 - 4.4e-07 29.4 0.0 0.00048 19.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 ORX88666.1 - 1.7e-06 27.9 0.6 0.063 13.0 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 ORX88666.1 - 1.9e-06 28.3 0.4 1.6 9.2 0.0 4.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX88666.1 - 3.3e-06 27.6 1.4 0.063 13.7 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORX88666.1 - 5.2e-06 26.5 0.2 0.099 12.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORX88666.1 - 1e-05 25.8 1.6 0.08 13.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX88666.1 - 1.2e-05 25.3 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 ORX88666.1 - 1.6e-05 24.8 0.3 0.11 12.3 0.0 3.3 3 0 0 3 3 2 2 Adenylylsulphate kinase ABC_ATPase PF09818.9 ORX88666.1 - 1.8e-05 23.8 0.6 0.034 12.9 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class NB-ARC PF00931.22 ORX88666.1 - 0.00053 19.2 0.0 0.075 12.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain G-alpha PF00503.20 ORX88666.1 - 0.00064 19.0 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 ORX88666.1 - 0.00068 20.2 0.0 0.45 11.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX88666.1 - 0.00075 20.1 0.0 1.8 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX88666.1 - 0.00096 19.3 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORX88666.1 - 0.0017 18.3 0.6 8.6 6.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ORX88666.1 - 0.002 17.9 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 ORX88666.1 - 0.0065 16.7 2.1 1.7 8.9 0.4 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ORX88666.1 - 0.0087 15.8 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORX88666.1 - 0.0089 15.6 0.0 4.8 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 ORX88666.1 - 0.0097 16.0 0.1 3 8.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 ORX88666.1 - 0.012 15.7 1.2 2.4 8.2 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Rad17 PF03215.15 ORX88666.1 - 0.013 15.5 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 ORX88666.1 - 0.017 14.9 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_25 PF13481.6 ORX88666.1 - 0.023 14.3 0.0 11 5.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORX88666.1 - 0.039 13.7 0.2 6.7 6.4 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ORX88666.1 - 0.042 14.1 0.0 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NEMP PF10225.9 ORX88666.1 - 0.048 13.3 1.0 0.74 9.4 0.1 2.5 2 0 0 2 2 2 0 NEMP family DUF815 PF05673.13 ORX88666.1 - 0.057 12.6 0.0 8.2 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 ORX88666.1 - 0.094 11.6 0.0 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.6 ORX88666.1 - 0.096 13.0 0.7 30 4.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 ORX88666.1 - 0.098 12.3 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 ORX88666.1 - 0.11 12.9 0.1 18 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX88666.1 - 0.11 12.8 0.0 34 4.9 0.0 3.1 2 0 0 2 2 2 0 RNA helicase DUF3987 PF13148.6 ORX88666.1 - 0.13 11.2 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TniB PF05621.11 ORX88666.1 - 0.17 11.3 0.1 32 3.9 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein Kinesin PF00225.23 ORX88668.1 - 9.9e-99 330.4 1.6 9.9e-99 330.4 1.6 2.9 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORX88668.1 - 3.5e-17 62.7 0.1 3.5e-17 62.7 0.1 4.0 4 1 2 6 6 6 1 Microtubule binding Microtub_bind PF13931.6 ORX88668.1 - 1.5e-06 28.6 0.0 1.5e-06 28.6 0.0 6.4 4 1 3 8 8 8 1 Kinesin-associated microtubule-binding AAA_22 PF13401.6 ORX88668.1 - 3.6 7.9 0.0 3.6 7.9 0.0 5.1 2 1 4 6 6 6 0 AAA domain Apolipoprotein PF01442.18 ORX88668.1 - 3.8 7.3 60.0 0.4 10.5 4.2 5.3 2 1 3 5 5 5 0 Apolipoprotein A1/A4/E domain EF-hand_1 PF00036.32 ORX88669.1 - 1.2e-27 93.3 7.9 2.8e-06 26.5 0.0 5.7 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 ORX88669.1 - 9e-27 90.7 6.7 1.6e-07 30.7 0.0 5.2 4 1 1 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 ORX88669.1 - 2.5e-23 82.3 7.6 8e-11 42.2 0.7 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORX88669.1 - 8.4e-19 66.2 5.6 2e-06 27.0 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORX88669.1 - 1.3e-17 63.4 10.7 2.6e-09 36.8 0.4 4.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 ORX88669.1 - 7.7e-05 22.9 0.2 0.34 11.3 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain Toprim_2 PF13155.6 ORX88669.1 - 0.033 14.6 0.0 0.38 11.2 0.0 2.4 2 1 0 2 2 2 0 Toprim-like DUF5640 PF18692.1 ORX88669.1 - 0.045 13.8 0.2 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5640) SPARC_Ca_bdg PF10591.9 ORX88669.1 - 0.046 14.0 0.5 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TRAPP PF04051.16 ORX88669.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component DUF5580 PF17743.1 ORX88669.1 - 0.2 10.1 0.0 7.6 4.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5580) Caleosin PF05042.13 ORX88669.1 - 0.37 10.7 5.5 19 5.1 0.0 3.9 1 1 3 4 4 4 0 Caleosin related protein FAM72 PF14976.6 ORX88670.1 - 2.9e-25 89.1 3.3 3.9e-25 88.7 3.3 1.1 1 0 0 1 1 1 1 FAM72 protein zinc-ribbons_6 PF07191.12 ORX88670.1 - 0.00091 19.2 5.5 0.036 14.0 0.3 2.3 2 0 0 2 2 2 2 zinc-ribbons Yippee-Mis18 PF03226.14 ORX88670.1 - 0.52 10.5 6.5 1.4 9.2 5.8 2.0 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Spo7 PF03907.13 ORX88671.1 - 7.9e-07 28.8 1.5 1.5e-06 27.9 1.4 1.6 1 1 0 1 1 1 1 Spo7-like protein UPF0715 PF17094.5 ORX88671.1 - 0.017 15.7 0.5 0.025 15.1 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0715) Tmemb_18A PF09771.9 ORX88671.1 - 0.065 13.6 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 Claudin_2 PF13903.6 ORX88671.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RRM_1 PF00076.22 ORX88672.1 - 2.6e-30 104.1 0.0 8.4e-15 54.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX88672.1 - 0.019 15.1 0.0 6 7.1 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif Abhydrolase_8 PF06259.12 ORX88672.1 - 0.023 14.3 0.0 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase ADH_zinc_N_2 PF13602.6 ORX88679.1 - 1.8e-11 45.2 0.0 2.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX88679.1 - 5.9e-07 29.5 0.0 7.9e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.21 ORX88680.1 - 0.053 13.4 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF3472 PF11958.8 ORX88681.1 - 1.7e-10 41.7 5.2 2.8e-10 41.0 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX88681.1 - 0.0036 17.2 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) Myticin-prepro PF10690.9 ORX88682.1 - 0.0021 18.3 0.2 0.0032 17.7 0.2 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel CA_like PF10563.9 ORX88687.1 - 0.031 14.2 0.0 0.031 14.2 0.0 1.0 1 0 0 1 1 1 0 Putative carbonic anhydrase Pyr_redox_2 PF07992.14 ORX88688.1 - 1.1e-43 149.6 0.6 2.6e-37 128.6 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX88688.1 - 7.8e-16 58.4 1.3 2.1e-15 57.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX88688.1 - 6.4e-14 52.2 0.8 5.6e-12 45.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 ORX88688.1 - 1.2e-08 34.5 1.3 2.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX88688.1 - 6e-08 32.8 4.2 0.0047 17.1 0.4 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORX88688.1 - 0.00027 20.1 3.0 0.093 11.8 0.4 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 ORX88688.1 - 0.00089 18.9 5.1 0.5 9.9 0.6 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORX88688.1 - 0.0014 17.8 3.4 2.1 7.3 0.2 3.3 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 ORX88688.1 - 0.0031 16.3 5.0 1.8 7.2 0.0 3.1 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 ORX88688.1 - 0.0079 16.2 1.9 3.5 7.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding TusA PF01206.17 ORX88688.1 - 0.032 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Sulfurtransferase TusA 3HCDH_N PF02737.18 ORX88688.1 - 0.065 13.1 0.8 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ORX88688.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 ORX88688.1 - 0.15 11.3 0.1 0.15 11.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain DUF1188 PF06690.11 ORX88688.1 - 0.17 11.4 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Ecm29 PF13001.7 ORX88688.1 - 0.22 10.2 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser NAD_binding_7 PF13241.6 ORX88688.1 - 0.25 11.8 0.6 1.2 9.6 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.18 ORX88688.1 - 0.33 11.2 2.4 0.84 9.9 0.1 2.7 3 0 0 3 3 3 0 TrkA-N domain GST_C PF00043.25 ORX88689.1 - 3.8e-09 36.6 0.0 5.9e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX88689.1 - 1.5e-07 31.3 0.1 5.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX88689.1 - 3.5e-06 27.1 0.0 6.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX88689.1 - 8.5e-05 23.1 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX88689.1 - 0.012 16.0 0.2 0.18 12.2 0.1 2.3 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain Ribosomal_L35Ae PF01247.18 ORX88691.1 - 3.7e-45 152.0 0.8 4.2e-45 151.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORX88691.1 - 0.03 14.5 0.1 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain DEAD PF00270.29 ORX88692.1 - 7.1e-49 165.9 0.0 1.8e-48 164.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX88692.1 - 1.2e-31 109.3 0.0 3.1e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX88692.1 - 0.016 15.2 0.0 0.058 13.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORX88692.1 - 0.084 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NAD_binding_10 PF13460.6 ORX88693.1 - 1.4e-07 31.6 0.0 3.6e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX88693.1 - 1.2e-06 28.2 0.0 4.3e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORX88693.1 - 0.00021 20.6 1.1 0.004 16.4 1.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 ORX88693.1 - 0.0011 18.1 0.0 0.0081 15.2 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ORX88693.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ORX88693.1 - 0.0015 17.7 0.0 0.037 13.1 0.0 2.5 2 1 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 ORX88693.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 ORX88693.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family CAS_CSE1 PF03378.15 ORX88694.1 - 2.2e-156 520.8 5.5 2.2e-156 520.8 5.5 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 ORX88694.1 - 7.2e-124 413.3 5.5 7.2e-124 413.3 5.5 2.1 2 1 0 2 2 2 1 Cse1 UME PF08064.13 ORX88694.1 - 0.00013 21.8 0.1 0.79 9.7 0.0 3.7 3 2 0 3 3 3 2 UME (NUC010) domain UCH_1 PF13423.6 ORX88696.1 - 1.3e-100 337.1 5.4 1.9e-100 336.6 5.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 ORX88696.1 - 4.8e-22 79.2 0.0 1.4e-21 77.7 0.0 1.9 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 ORX88696.1 - 2.9e-16 59.7 1.0 4.5e-16 59.1 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 ORX88696.1 - 2.3 9.2 4.5 85 4.3 0.5 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat fn2 PF00040.19 ORX88699.1 - 3.6e-05 24.0 0.8 0.00018 21.7 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type II domain Ribosomal_S25 PF03297.15 ORX88700.1 - 1.6e-42 143.8 1.1 1.8e-42 143.6 1.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_CodY PF08222.11 ORX88700.1 - 0.0018 17.8 0.4 0.0028 17.1 0.1 1.5 2 0 0 2 2 2 1 CodY helix-turn-helix domain MarR_2 PF12802.7 ORX88700.1 - 0.012 15.4 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 MarR family DNA_pol_phi PF04931.13 ORX88701.1 - 8.6e-239 794.6 29.7 8.6e-239 794.6 29.7 1.6 2 1 0 2 2 2 1 DNA polymerase phi Nop14 PF04147.12 ORX88701.1 - 6e-05 21.5 19.5 0.00016 20.1 19.5 1.6 1 0 0 1 1 1 1 Nop14-like family SPG48 PF14764.6 ORX88701.1 - 0.038 14.5 1.4 0.93 10.0 0.0 3.8 4 0 0 4 4 4 0 AP-5 complex subunit, vesicle trafficking SDA1 PF05285.12 ORX88701.1 - 0.097 12.1 23.9 0.25 10.7 23.9 1.6 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ORX88701.1 - 2.7 6.2 17.6 5 5.3 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 ORX88701.1 - 4.7 5.6 22.8 17 3.8 22.8 2.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 WAPL PF07814.13 ORX88702.1 - 2.3e-42 145.1 5.7 3.2e-42 144.7 5.7 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 ORX88702.1 - 0.0011 18.2 2.0 0.11 11.7 0.1 2.5 3 0 0 3 3 3 2 Wap1 domain DUF3402 PF11882.8 ORX88703.1 - 2.6e-102 343.3 16.5 4.4e-100 336.0 16.5 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 ORX88703.1 - 7.3e-55 186.2 0.2 1.4e-54 185.2 0.2 1.5 1 0 0 1 1 1 1 N1221-like protein CENP-W PF15510.6 ORX88703.1 - 0.068 13.4 2.3 0.42 10.9 0.1 2.5 2 0 0 2 2 2 0 CENP-W protein Rhomboid PF01694.22 ORX88704.1 - 0.67 9.9 7.5 1.5 8.8 7.5 1.5 1 0 0 1 1 1 0 Rhomboid family DUF378 PF04070.12 ORX88704.1 - 2.7 7.9 6.5 0.19 11.7 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF378) Csm1 PF12539.8 ORX88705.1 - 3.9e-17 62.7 0.9 7.1e-17 61.8 0.9 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TSA PF03249.13 ORX88705.1 - 0.053 12.3 5.1 0.09 11.6 5.1 1.3 1 0 0 1 1 1 0 Type specific antigen NPV_P10 PF05531.12 ORX88705.1 - 2 8.9 5.7 4.3 7.9 3.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.11 ORX88705.1 - 4.6 7.5 29.3 0.12 12.6 10.7 3.7 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 Aha1_N PF09229.11 ORX88706.1 - 1.2e-37 129.2 1.7 1.9e-37 128.5 1.7 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORX88706.1 - 1.3e-17 64.2 0.3 2.6e-17 63.2 0.3 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein LETM1 PF07766.13 ORX88707.1 - 2.9e-40 138.3 3.5 1.4e-38 132.8 3.5 2.0 1 1 0 1 1 1 1 LETM1-like protein SAP PF02037.27 ORX88707.1 - 0.019 14.7 0.1 0.055 13.2 0.1 1.8 1 0 0 1 1 1 0 SAP domain SAP30_Sin3_bdg PF13867.6 ORX88707.1 - 0.093 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Phage_int_SAM_5 PF13102.6 ORX88707.1 - 0.39 11.1 2.3 0.38 11.1 0.6 1.9 2 1 0 2 2 2 0 Phage integrase SAM-like domain Peptidase_M10 PF00413.24 ORX88708.1 - 0.19 11.6 0.0 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Matrixin ECH_2 PF16113.5 ORX88709.1 - 4.3e-131 437.4 0.0 5.5e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORX88709.1 - 1e-31 110.2 0.0 1.6e-29 103.0 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase BRAP2 PF07576.12 ORX88710.1 - 6.4e-34 116.1 0.1 1.3e-33 115.1 0.1 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 ORX88710.1 - 5.5e-19 68.2 4.5 5.5e-19 68.2 4.5 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 ORX88710.1 - 1.1e-07 32.1 10.2 1.1e-07 32.1 10.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX88710.1 - 1.8e-05 24.5 10.0 4.6e-05 23.2 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX88710.1 - 3.8e-05 23.9 7.0 3.8e-05 23.9 7.0 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX88710.1 - 0.00011 22.2 4.1 0.00026 21.0 4.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORX88710.1 - 0.00012 22.1 5.7 0.00039 20.4 5.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORX88710.1 - 0.0007 19.4 8.9 0.0007 19.4 8.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX88710.1 - 0.0022 17.7 6.7 0.0062 16.3 6.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger DUF4407 PF14362.6 ORX88710.1 - 0.0032 16.9 11.0 0.0049 16.3 11.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.6 ORX88710.1 - 0.0044 16.9 6.8 0.0044 16.9 6.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORX88710.1 - 0.018 14.8 3.1 0.018 14.8 3.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain SPX PF03105.19 ORX88710.1 - 0.024 14.6 10.5 0.011 15.7 7.4 1.8 2 0 0 2 2 2 0 SPX domain T4SS PF07996.11 ORX88710.1 - 0.063 13.7 8.5 0.12 12.8 8.5 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins RRM_1 PF00076.22 ORX88710.1 - 0.17 11.8 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3584 PF12128.8 ORX88710.1 - 0.18 9.2 14.2 0.27 8.7 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PHF5 PF03660.14 ORX88710.1 - 0.2 11.9 6.4 0.38 11.0 6.4 1.4 1 0 0 1 1 1 0 PHF5-like protein Prok-RING_4 PF14447.6 ORX88710.1 - 1.6 8.7 17.8 0.25 11.2 5.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 SlyX PF04102.12 ORX88710.1 - 1.8 9.3 17.0 17 6.1 7.9 3.2 1 1 1 2 2 2 0 SlyX Baculo_PEP_C PF04513.12 ORX88710.1 - 1.8 8.6 6.5 0.86 9.6 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MRP-S26 PF14943.6 ORX88710.1 - 1.9 8.4 12.4 3.4 7.6 12.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Sec34 PF04136.15 ORX88710.1 - 2.6 7.9 10.4 5.9 6.8 7.7 2.3 1 1 1 2 2 2 0 Sec34-like family Fib_alpha PF08702.10 ORX88710.1 - 3.1 8.0 11.8 4.8 7.4 0.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 ORX88710.1 - 4.7 7.2 19.9 4.4 7.3 0.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 ORX88710.1 - 5.9 5.3 5.4 11 4.4 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2968 PF11180.8 ORX88710.1 - 6.8 6.3 16.4 5.2 6.6 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) OrfB_Zn_ribbon PF07282.11 ORX88710.1 - 7.8 6.5 9.1 13 5.8 3.6 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_4 PF15227.6 ORX88710.1 - 8.1 6.7 9.7 2.8 8.2 6.1 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Romo1 PF10247.9 ORX88711.1 - 3e-23 82.0 6.1 3.2e-23 81.9 6.1 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 ORX88711.1 - 0.0043 17.4 3.1 0.0055 17.1 3.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3021 PF11457.8 ORX88711.1 - 0.062 13.6 0.9 0.074 13.4 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) GTP_EFTU PF00009.27 ORX88712.1 - 1.3e-49 168.4 0.0 1.9e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 ORX88712.1 - 2.1e-35 122.0 7.5 3.6e-35 121.2 7.5 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 ORX88712.1 - 2e-24 85.7 0.0 4.9e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ORX88712.1 - 1.3e-22 79.6 0.0 3.3e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORX88712.1 - 2.7e-11 43.7 0.2 8e-11 42.2 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORX88712.1 - 8e-06 25.9 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORX88712.1 - 1.1e-05 25.5 0.2 2.3e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 ORX88712.1 - 7.2e-05 22.2 1.5 8e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Septin Roc PF08477.13 ORX88712.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORX88712.1 - 0.041 13.9 0.1 4 7.5 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Ras PF00071.22 ORX88712.1 - 0.043 13.4 0.1 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 Ras family Sulfate_transp PF00916.20 ORX88713.1 - 5.2e-114 380.9 16.8 6.6e-114 380.6 16.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX88713.1 - 4.1e-13 49.0 0.0 7.6e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORX88713.1 - 0.00066 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORX88713.1 - 0.0027 18.1 2.6 0.0027 18.1 2.6 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily Prefoldin_2 PF01920.20 ORX88714.1 - 1.8e-08 34.3 3.0 2.4e-08 33.9 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Siah-Interact_N PF09032.11 ORX88714.1 - 0.023 15.0 0.1 0.023 15.0 0.1 1.7 2 1 0 2 2 2 0 Siah interacting protein, N terminal PTCB-BRCT PF12738.7 ORX88715.1 - 2.1e-69 229.4 5.2 1.7e-19 69.5 0.1 8.3 8 0 0 8 8 8 7 twin BRCT domain BRCT PF00533.26 ORX88715.1 - 4.5e-69 228.8 4.7 3.7e-12 46.4 0.0 7.6 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORX88715.1 - 2e-32 111.4 7.4 3.6e-06 27.3 0.0 7.6 7 0 0 7 7 7 7 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 ORX88715.1 - 3.3e-16 59.0 0.0 3.4e-05 23.6 0.0 6.6 7 0 0 7 7 7 3 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 ORX88715.1 - 1.1e-11 44.8 0.1 0.046 14.0 0.0 7.2 7 0 0 7 7 7 3 DNA ligase 3 BRCT domain TPP_enzyme_N PF02776.18 ORX88716.1 - 7.1e-57 191.8 0.0 1.4e-56 190.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORX88716.1 - 1.7e-51 174.0 0.2 6.9e-50 168.8 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORX88716.1 - 3.4e-39 133.7 0.2 7.9e-39 132.5 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Herpes_IR6 PF06307.12 ORX88716.1 - 0.17 11.4 0.1 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus IR6 protein UcrQ PF02939.16 ORX88717.1 - 4.1e-33 113.2 0.4 4.6e-33 113.0 0.4 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 ORX88717.1 - 0.026 14.9 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Transthyretin PF00576.21 ORX88718.1 - 2.7e-37 127.8 0.0 3e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family RAP1 PF07218.11 ORX88719.1 - 0.41 8.9 3.3 0.47 8.7 3.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) VDE PF07137.11 ORX88719.1 - 1 8.8 7.6 1.8 8.0 7.6 1.4 1 1 0 1 1 1 0 VDE lipocalin domain HAP1_N PF04849.13 ORX88720.1 - 8.6e-07 28.4 26.4 2.7e-05 23.5 15.2 3.2 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 ORX88720.1 - 0.00018 21.6 3.4 0.00018 21.6 3.4 3.0 1 1 1 3 3 3 1 Tropomyosin like Laminin_II PF06009.12 ORX88720.1 - 0.00095 19.2 0.8 0.00095 19.2 0.8 3.0 2 1 0 3 3 3 1 Laminin Domain II GIT_CC PF16559.5 ORX88720.1 - 0.004 17.0 7.5 0.021 14.7 0.1 3.4 2 1 1 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor Indigoidine_A PF04227.12 ORX88720.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Indigoidine synthase A like protein CENP-F_leu_zip PF10473.9 ORX88720.1 - 0.041 13.9 26.9 0.066 13.2 1.6 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C4H2 PF10146.9 ORX88720.1 - 0.046 14.0 0.3 0.046 14.0 0.3 2.9 1 1 2 3 3 3 0 Zinc finger-containing protein DUF1664 PF07889.12 ORX88720.1 - 0.45 10.6 14.5 0.34 10.9 1.7 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF919 PF06034.11 ORX88720.1 - 0.64 9.9 5.2 0.33 10.8 0.9 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) ATG16 PF08614.11 ORX88720.1 - 0.72 10.0 24.3 0.25 11.6 11.3 2.8 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 ORX88720.1 - 0.87 9.7 10.9 2.4 8.3 0.1 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 ORX88720.1 - 0.9 9.6 23.4 3.5 7.7 13.0 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 ORX88720.1 - 0.93 9.6 18.4 0.71 9.9 1.1 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 ORX88720.1 - 1.3 9.6 23.3 2.2 8.8 4.2 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 ORX88720.1 - 2.1 8.8 20.9 0.34 11.3 2.2 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 ORX88720.1 - 2.9 8.0 18.5 0.073 13.2 4.5 4.1 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Occludin_ELL PF07303.13 ORX88720.1 - 4.5 8.1 8.5 2.1 9.1 0.5 3.3 2 1 1 3 3 3 0 Occludin homology domain LPP PF04728.13 ORX88720.1 - 7.4 7.1 0.0 7.4 7.1 0.0 4.1 4 2 1 5 5 4 0 Lipoprotein leucine-zipper SET PF00856.28 ORX88721.1 - 1.1e-19 71.4 0.2 3.6e-19 69.8 0.2 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 ORX88721.1 - 2.7e-13 50.5 8.2 2.7e-13 50.5 8.2 2.2 2 0 0 2 2 2 1 Pre-SET motif SMI1_KNR4 PF09346.10 ORX88723.1 - 0.017 15.6 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) F-box PF00646.33 ORX88723.1 - 0.064 13.2 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORX88723.1 - 0.1 12.5 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 ORX88724.1 - 2.7e-17 62.7 25.9 3.7e-17 62.3 25.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX88724.1 - 8.7e-14 51.5 9.3 8.7e-14 51.5 9.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX88724.1 - 7.7e-05 21.7 0.4 0.026 13.4 5.7 2.1 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORX88724.1 - 0.11 11.5 12.3 0.049 12.6 8.9 2.1 2 1 1 3 3 3 0 PUCC protein CPP1-like PF11833.8 ORX88724.1 - 10 5.7 6.4 1.9 8.1 2.4 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WD40 PF00400.32 ORX88725.1 - 1.9e-59 196.2 14.8 4.5e-09 36.8 0.0 7.8 8 0 0 8 8 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORX88725.1 - 3e-29 101.1 8.5 4.3e-29 100.6 8.5 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORX88725.1 - 3e-23 81.9 0.0 9.9e-05 22.6 0.0 6.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX88725.1 - 5.2e-10 39.1 0.0 0.01 15.2 0.0 4.7 6 0 0 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 ORX88725.1 - 2.9e-09 36.4 0.2 0.21 10.5 0.0 5.1 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORX88725.1 - 5.7e-06 26.3 0.0 0.019 14.9 0.0 3.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ORX88725.1 - 1e-05 25.0 0.1 0.54 9.5 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 ORX88725.1 - 1.5e-05 24.8 0.1 13 5.9 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 ORX88725.1 - 3.4e-05 22.7 0.2 0.35 9.5 0.0 3.8 3 1 2 5 5 5 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 ORX88725.1 - 0.0022 17.7 0.8 3.3 7.5 0.0 4.6 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 ORX88725.1 - 0.0031 16.1 0.3 0.038 12.5 0.1 2.3 1 1 2 3 3 3 2 Cytochrome D1 heme domain CEP63 PF17045.5 ORX88725.1 - 0.023 14.6 3.9 0.036 14.0 3.9 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Peptidase_S9_N PF02897.15 ORX88725.1 - 0.03 13.1 0.0 1.1 8.0 0.0 2.8 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Spc7 PF08317.11 ORX88725.1 - 0.055 12.3 2.8 0.079 11.8 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 ORX88725.1 - 0.061 12.8 3.1 0.09 12.2 3.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5122 PF17164.4 ORX88725.1 - 0.14 12.5 0.5 68 3.9 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller DUF3450 PF11932.8 ORX88725.1 - 0.27 10.5 4.9 0.5 9.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPX2 PF06886.11 ORX88725.1 - 3.4 8.0 6.1 6 7.2 6.1 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) SRP14 PF02290.15 ORX88726.1 - 1.1e-22 80.2 0.4 1.5e-22 79.7 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Sec23_trunk PF04811.15 ORX88727.1 - 1.4e-72 244.2 0.0 2e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORX88727.1 - 1.3e-25 89.2 0.1 2.3e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORX88727.1 - 1.1e-17 64.6 0.0 2.3e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORX88727.1 - 2.7e-17 62.5 4.7 5.4e-17 61.6 4.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORX88727.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORX88727.1 - 0.00065 19.1 0.1 0.0015 17.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain ACT PF01842.25 ORX88728.1 - 1.4e-10 40.7 0.3 3.7e-10 39.4 0.3 1.7 1 1 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORX88728.1 - 6.6e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain HlyIII PF03006.20 ORX88729.1 - 3.3e-58 197.0 25.8 4.2e-58 196.7 25.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related AAA-ATPase_like PF09820.9 ORX88729.1 - 0.05 13.0 0.1 0.095 12.1 0.1 1.6 1 0 0 1 1 1 0 Predicted AAA-ATPase SPC12 PF06645.13 ORX88729.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TarH PF02203.15 ORX88729.1 - 0.21 11.5 0.1 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue Toxin_trans PF07952.12 ORX88729.1 - 0.28 10.2 2.2 0.9 8.6 0.6 2.0 1 1 1 2 2 2 0 Clostridium neurotoxin, Translocation domain DUF2680 PF10925.8 ORX88729.1 - 0.32 11.0 1.4 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) CENP-C_C PF11699.8 ORX88730.1 - 3.1e-26 91.4 0.2 5.6e-26 90.6 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 ORX88730.1 - 2.5e-09 37.9 6.1 2.5e-09 37.9 6.1 2.0 1 1 1 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 ORX88730.1 - 1.3e-05 24.8 0.0 9.7e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 ORX88730.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ORX88730.1 - 0.021 14.5 0.1 0.27 11.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF861) DUF3128 PF11326.8 ORX88731.1 - 2.3e-23 82.4 6.3 2.9e-23 82.0 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF5512 PF17631.2 ORX88731.1 - 0.038 14.0 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5512) UPF0203 PF05254.12 ORX88731.1 - 0.19 12.0 6.4 0.25 11.6 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) GPI-anchored PF10342.9 ORX88732.1 - 7.9e-13 49.0 0.1 1.3e-12 48.2 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1180 PF06679.12 ORX88732.1 - 0.14 12.6 0.7 0.24 11.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HEAT PF02985.22 ORX88733.1 - 2.5e-18 64.6 12.9 0.0087 16.2 0.0 8.5 8 1 1 9 9 9 6 HEAT repeat HEAT_2 PF13646.6 ORX88733.1 - 2e-09 37.7 0.1 0.66 10.4 0.0 5.6 4 2 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 ORX88733.1 - 6.2e-06 26.3 6.1 0.0055 16.8 0.1 4.4 1 1 4 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORX88733.1 - 0.00012 21.8 0.6 0.57 9.7 0.1 3.4 3 1 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.20 ORX88733.1 - 0.00017 20.3 1.5 0.22 10.1 0.1 3.1 2 1 0 3 3 3 2 Adaptin N terminal region Ecm29 PF13001.7 ORX88733.1 - 0.0015 17.3 0.8 1 7.9 0.1 2.8 2 1 1 3 3 3 2 Proteasome stabiliser B56 PF01603.20 ORX88733.1 - 0.029 13.3 0.6 0.14 11.1 0.2 2.0 1 1 1 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 ORX88733.1 - 0.039 13.9 1.0 0.41 10.5 0.1 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 ORX88733.1 - 0.083 13.0 1.3 11 6.3 0.0 3.9 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Ribonuclease_T2 PF00445.18 ORX88734.1 - 5.4e-39 134.3 0.3 7.4e-39 133.9 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ABC_tran PF00005.27 ORX88735.1 - 2.1e-50 170.8 0.1 6.4e-33 114.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORX88735.1 - 3.8e-39 135.0 36.4 4e-21 75.9 14.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 ORX88735.1 - 3.6e-07 29.8 0.9 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX88735.1 - 5.9e-06 26.3 2.3 0.05 13.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX88735.1 - 8.6e-06 25.8 0.1 0.036 14.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 ORX88735.1 - 8.8e-06 25.3 4.6 0.029 13.8 0.2 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX88735.1 - 2.2e-05 24.9 0.0 0.063 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORX88735.1 - 0.00022 21.8 1.2 0.84 10.1 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORX88735.1 - 0.00058 19.8 2.0 0.71 9.6 0.1 3.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system TrwB_AAD_bind PF10412.9 ORX88735.1 - 0.00084 18.4 0.7 0.11 11.4 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 ORX88735.1 - 0.0027 17.3 0.5 1.7 8.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORX88735.1 - 0.0032 16.6 0.5 0.049 12.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 ORX88735.1 - 0.0069 16.1 2.5 0.78 9.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 ORX88735.1 - 0.0089 16.1 4.0 0.37 10.8 0.4 2.8 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 ORX88735.1 - 0.011 15.3 1.1 2.2 7.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 ORX88735.1 - 0.012 15.3 1.2 9.8 5.9 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 ORX88735.1 - 0.016 15.3 0.4 0.016 15.3 0.4 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 ORX88735.1 - 0.019 15.3 2.2 4.6 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 ORX88735.1 - 0.024 14.6 1.7 5.3 6.9 0.1 2.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ORX88735.1 - 0.032 13.4 0.4 3.1 6.9 0.1 2.7 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 ORX88735.1 - 0.051 13.8 1.8 5 7.4 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 ORX88735.1 - 0.1 12.1 0.7 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 ORX88735.1 - 0.14 11.4 1.4 3.5 6.9 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 ORX88735.1 - 0.18 11.5 3.6 3.8 7.1 0.2 2.4 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 ORX88735.1 - 0.23 10.4 0.8 2.1 7.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 ORX88735.1 - 0.35 9.6 5.8 1.3 7.7 0.1 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 ORX88735.1 - 0.47 10.3 3.2 21 5.0 0.1 3.3 3 0 0 3 3 3 0 NTPase MobB PF03205.14 ORX88735.1 - 0.48 10.3 3.2 2.3 8.1 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 ORX88735.1 - 0.49 9.9 5.7 4.5 6.7 0.1 3.2 3 0 0 3 3 3 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORX88735.1 - 0.57 9.5 2.6 0.84 8.9 0.2 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ORX88735.1 - 0.7 9.6 3.2 1.3 8.8 0.4 2.4 2 1 0 2 2 2 0 AAA domain Glyco_transf_28 PF03033.20 ORX88736.1 - 2.8e-28 98.7 0.0 5.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 ORX88736.1 - 2.2e-18 66.2 0.3 8.1e-17 61.1 0.0 2.5 2 0 0 2 2 2 1 GRAM domain PH PF00169.29 ORX88736.1 - 9.1e-12 45.4 0.3 1e-10 42.0 0.0 2.7 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 ORX88736.1 - 4e-08 32.5 0.0 7.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 ORX88736.1 - 0.012 16.0 0.4 0.14 12.6 0.4 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Vps36_ESCRT-II PF11605.8 ORX88736.1 - 0.044 14.0 0.1 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 Glyco_hydro_16 PF00722.21 ORX88740.1 - 7.2e-21 74.4 0.1 1.5e-20 73.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 C2 PF00168.30 ORX88741.1 - 2.1e-07 31.2 0.0 6.2e-07 29.7 0.0 1.7 1 1 1 2 2 2 1 C2 domain RasGAP PF00616.19 ORX88741.1 - 4.3e-07 29.8 0.0 6.3e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase SinI PF08671.10 ORX88741.1 - 0.12 12.2 0.1 0.43 10.4 0.1 2.0 1 0 0 1 1 1 0 Anti-repressor SinI zf-C3HC4_3 PF13920.6 ORX88742.1 - 1.3e-08 34.6 17.1 2.3e-08 33.8 17.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VHL_C PF17211.3 ORX88742.1 - 0.014 15.4 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 VHL box domain Prok-RING_4 PF14447.6 ORX88742.1 - 0.17 11.8 15.6 0.31 11.0 15.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Tmemb_14 PF03647.13 ORX88743.1 - 0.0034 18.1 0.6 0.011 16.4 0.2 2.0 2 1 0 2 2 2 1 Transmembrane proteins 14C DSPc PF00782.20 ORX88744.1 - 3.7e-07 30.0 0.0 4.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX88744.1 - 7.3e-07 29.0 0.0 9.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORX88744.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 ORX88744.1 - 0.097 12.8 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Amidase_2 PF01510.25 ORX88745.1 - 4e-18 66.1 0.3 5.4e-18 65.7 0.3 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase SH3_3 PF08239.11 ORX88745.1 - 6e-12 45.7 0.6 2.2e-11 43.8 0.3 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain Kunitz_BPTI PF00014.23 ORX88747.1 - 9.7e-45 150.6 47.6 1.2e-12 47.8 5.3 4.3 4 0 0 4 4 4 4 Kunitz/Bovine pancreatic trypsin inhibitor domain Trypan_PARP PF05887.11 ORX88747.1 - 1.4e-07 31.5 21.1 0.021 14.8 1.0 4.1 4 0 0 4 4 4 3 Procyclic acidic repetitive protein (PARP) A_amylase_inhib PF01356.19 ORX88747.1 - 3.3e-07 30.2 4.7 1.4 8.9 0.0 4.7 4 1 1 5 5 5 3 Alpha amylase inhibitor zf_CCCH_5 PF18384.1 ORX88747.1 - 0.014 15.5 19.6 4.1 7.6 0.1 5.6 7 0 0 7 7 7 0 Unkempt Zinc finger domain 1 (Znf1) NUMOD1 PF07453.13 ORX88747.1 - 0.17 12.2 0.0 1.3e+02 3.0 0.0 3.4 3 0 0 3 3 3 0 NUMOD1 domain JSRP PF15312.6 ORX88747.1 - 0.18 11.8 3.2 12 5.9 0.2 2.6 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Bradykinin PF06753.12 ORX88747.1 - 1.5 8.6 4.3 1.1e+02 2.6 0.1 3.5 3 0 0 3 3 3 0 Bradykinin Response_reg PF00072.24 ORX88748.1 - 4.8e-20 71.8 0.0 7.8e-20 71.1 0.0 1.3 1 1 0 1 1 1 1 Response regulator receiver domain Fun_ATP-synt_8 PF05933.13 ORX88748.1 - 0.13 12.4 0.2 0.31 11.2 0.2 1.6 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) NPL4 PF05021.15 ORX88749.1 - 6.8e-132 439.5 0.0 8.7e-132 439.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 ORX88749.1 - 2.2e-70 235.4 0.4 4.4e-70 234.5 0.4 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 ORX88749.1 - 3.9e-09 36.9 0.0 7.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 ORX88749.1 - 0.0017 17.6 3.2 0.0017 17.6 3.2 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Ribosomal_L35Ae PF01247.18 ORX88751.1 - 1.4e-45 153.4 0.7 1.6e-45 153.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORX88751.1 - 0.0091 16.2 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Methyltransf_34 PF11312.8 ORX88752.1 - 3e-53 181.1 0.1 6.6e-53 179.9 0.1 1.6 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase CNH PF00780.22 ORX88753.1 - 1.7e-50 172.1 0.0 3.2e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORX88753.1 - 2e-36 125.9 1.3 3.7e-36 125.1 1.3 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORX88753.1 - 7e-12 45.6 1.5 5.4e-05 23.3 0.0 2.4 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 ORX88753.1 - 2.2e-06 28.1 0.1 8.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 ORX88753.1 - 0.0018 18.1 0.1 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain THDPS_N PF14790.6 ORX88753.1 - 0.19 11.6 1.7 1.3 8.8 0.1 2.9 3 1 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Sgf11 PF08209.11 ORX88753.1 - 0.59 9.8 3.4 0.61 9.7 1.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF3336 PF11815.8 ORX88755.1 - 1.8e-44 150.8 3.5 3e-44 150.1 3.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORX88755.1 - 4.3e-17 63.0 0.1 5.3e-16 59.4 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Trypsin PF00089.26 ORX88757.1 - 1e-15 58.1 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 ORX88757.1 - 0.00021 21.6 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) zf-RING_2 PF13639.6 ORX88758.1 - 2.6e-15 56.5 35.3 1.6e-10 41.1 18.0 3.2 2 1 1 3 3 3 2 Ring finger domain zf-rbx1 PF12678.7 ORX88758.1 - 1.9e-10 40.9 31.8 3.1e-07 30.6 16.9 3.1 2 2 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORX88758.1 - 3.4e-10 39.7 28.5 4.1e-05 23.5 5.2 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX88758.1 - 1.5e-09 37.7 24.5 9.6e-06 25.5 8.5 3.8 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 ORX88758.1 - 2.4e-09 36.9 28.2 0.00024 20.9 5.5 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORX88758.1 - 1.6e-07 31.3 17.8 0.00022 21.2 7.5 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 ORX88758.1 - 2.7e-07 30.2 24.9 9.3e-05 22.1 10.8 4.3 4 0 0 4 4 4 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX88758.1 - 4.2e-07 29.7 35.9 6.7e-05 22.7 17.6 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX88758.1 - 0.00021 21.1 11.8 0.00021 21.1 11.8 3.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORX88758.1 - 0.001 18.9 27.4 0.0034 17.2 12.8 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORX88758.1 - 0.0023 18.1 20.2 0.064 13.4 3.6 3.2 1 1 2 3 3 3 2 FANCL C-terminal domain PHD PF00628.29 ORX88758.1 - 0.013 15.4 21.3 0.016 15.1 0.6 3.7 3 1 0 3 3 3 0 PHD-finger zinc_ribbon_9 PF14369.6 ORX88758.1 - 0.07 13.4 15.5 0.088 13.1 0.2 4.4 4 0 0 4 4 4 0 zinc-ribbon DUF4329 PF14220.6 ORX88758.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) zf-Nse PF11789.8 ORX88758.1 - 0.48 10.3 19.3 2.4 8.1 12.2 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 ORX88758.1 - 2.3 8.4 15.3 2.6 8.2 8.7 3.0 2 1 0 2 2 2 0 RING-variant domain zf-RING_6 PF14835.6 ORX88758.1 - 2.4 8.1 11.7 2.6 8.0 5.5 2.8 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 ORX88758.1 - 5.3 6.8 29.8 0.38 10.4 13.5 3.7 3 2 1 4 4 4 0 Zinc-ribbon, C4HC2 type HPP PF04982.13 ORX88759.1 - 4.7e-29 101.1 4.8 6.3e-29 100.6 4.8 1.2 1 0 0 1 1 1 1 HPP family Ribosomal_L37e PF01907.19 ORX88760.1 - 1.1e-27 95.9 12.0 1.7e-27 95.3 12.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX88760.1 - 0.011 15.7 1.6 0.017 15.2 1.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ORX88760.1 - 0.034 14.2 0.7 0.048 13.7 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SelR PF01641.18 ORX88760.1 - 0.039 14.0 1.2 0.049 13.7 1.1 1.3 1 1 0 1 1 1 0 SelR domain zf-RING_5 PF14634.6 ORX88760.1 - 0.072 13.1 3.6 0.11 12.5 3.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 ORX88760.1 - 0.31 10.5 3.7 2.3 7.7 3.7 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 ORX88760.1 - 0.59 9.7 4.3 2.3 7.8 0.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon MFS_2 PF13347.6 ORX88761.1 - 1.7e-10 40.1 2.7 1.7e-10 40.1 2.7 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 ORX88761.1 - 8.6e-07 28.3 0.6 1.9e-06 27.1 0.6 1.5 1 0 0 1 1 1 1 PUCC protein Ldh_1_N PF00056.23 ORX88762.1 - 2.9e-36 124.7 0.3 4.4e-36 124.1 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX88762.1 - 1.2e-18 67.6 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DAO PF01266.24 ORX88762.1 - 5.6e-05 22.9 0.1 0.00019 21.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX88762.1 - 0.0037 16.6 0.2 0.0053 16.1 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORX88762.1 - 0.059 13.8 0.1 0.2 12.1 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding PEP_hydrolase PF09370.10 ORX88762.1 - 0.082 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like NMN_transporter PF04973.12 ORX88763.1 - 0.043 13.8 10.3 0.06 13.3 10.3 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Pkr1 PF08636.10 ORX88763.1 - 0.16 12.2 3.9 0.26 11.4 0.2 2.4 2 0 0 2 2 2 0 ER protein Pkr1 Tetraspanin PF00335.20 ORX88763.1 - 0.26 11.0 13.8 0.71 9.5 13.8 1.8 1 1 0 1 1 1 0 Tetraspanin family CD20 PF04103.15 ORX88763.1 - 0.71 9.9 11.2 0.36 10.9 8.7 1.7 2 0 0 2 2 2 0 CD20-like family Collectrin PF16959.5 ORX88763.1 - 0.88 9.3 3.4 0.95 9.2 0.9 2.0 2 0 0 2 2 2 0 Renal amino acid transporter DUF2981 PF11200.8 ORX88763.1 - 0.91 9.2 5.8 2.8 7.6 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4728 PF15860.5 ORX88763.1 - 1 10.1 11.3 0.051 14.3 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) DUF983 PF06170.12 ORX88763.1 - 2.1 8.8 7.3 6.2 7.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF2070 PF09843.9 ORX88763.1 - 2.6 6.2 6.5 3.2 5.9 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ras PF00071.22 ORX88764.1 - 2.1e-53 180.3 0.0 2.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX88764.1 - 6.2e-19 68.4 0.0 8.4e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX88764.1 - 3e-07 30.0 0.0 4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX88764.1 - 0.058 12.9 0.0 0.38 10.3 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.25 ORX88765.1 - 2.2e-59 201.0 0.0 3.8e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88765.1 - 1.1e-41 142.8 0.0 2.3e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX88765.1 - 9.7e-05 21.3 0.0 0.00025 20.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase OSR1_C PF12202.8 ORX88765.1 - 0.00032 20.9 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Cyclin PF08613.11 ORX88766.1 - 1.8e-36 125.9 0.5 4.2e-36 124.8 0.5 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX88766.1 - 0.05 13.4 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain PHO4 PF01384.20 ORX88768.1 - 3.8e-13 49.2 1.0 4.8e-13 48.9 1.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family ThrE PF06738.12 ORX88768.1 - 0.044 13.1 0.5 0.054 12.9 0.5 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter PHO4 PF01384.20 ORX88769.1 - 8.7e-43 146.6 1.3 9.5e-43 146.5 1.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF3421 PF11901.8 ORX88770.1 - 8.6e-36 122.4 1.4 5.8e-18 65.0 0.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Ank_4 PF13637.6 ORX88771.1 - 1.7e-11 44.4 0.0 2.2e-06 28.1 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX88771.1 - 3e-09 37.3 0.0 0.00077 20.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX88771.1 - 7e-07 29.1 0.1 0.03 14.8 0.1 3.3 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.6 ORX88771.1 - 1.1e-06 28.8 0.0 0.076 13.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Macoilin PF09726.9 ORX88771.1 - 6.1e-06 25.1 5.2 1.2e-05 24.2 5.2 1.4 1 0 0 1 1 1 1 Macoilin family Ank PF00023.30 ORX88771.1 - 5e-05 23.5 0.3 0.17 12.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Filament PF00038.21 ORX88771.1 - 0.00025 20.7 15.5 0.0057 16.3 10.3 2.2 2 0 0 2 2 2 1 Intermediate filament protein KilA-N PF04383.13 ORX88771.1 - 0.00027 20.7 3.6 0.00058 19.7 0.1 2.8 2 1 0 2 2 1 1 KilA-N domain TMF_TATA_bd PF12325.8 ORX88771.1 - 0.001 19.3 13.5 0.031 14.5 7.2 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding HR1 PF02185.16 ORX88771.1 - 0.0014 18.7 6.0 0.0014 18.7 6.0 3.3 2 2 1 3 3 3 1 Hr1 repeat DUF1664 PF07889.12 ORX88771.1 - 0.0062 16.6 8.4 1.1 9.3 5.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) HOOK PF05622.12 ORX88771.1 - 0.022 12.9 13.3 0.034 12.3 13.3 1.2 1 0 0 1 1 1 0 HOOK protein NPV_P10 PF05531.12 ORX88771.1 - 0.066 13.7 9.4 0.046 14.2 1.4 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.13 ORX88771.1 - 0.069 13.3 11.4 0.31 11.2 7.3 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc24 PF08286.11 ORX88771.1 - 0.07 13.4 9.7 1.6 9.0 6.3 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 VasL PF12486.8 ORX88771.1 - 0.072 13.0 5.4 0.21 11.5 5.4 1.8 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL CENP-F_leu_zip PF10473.9 ORX88771.1 - 0.078 13.0 15.5 2.8 7.9 10.4 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 ORX88771.1 - 0.087 12.1 14.4 0.26 10.6 9.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 ORX88771.1 - 0.095 12.8 15.4 0.04 14.0 6.5 3.4 3 1 0 3 3 3 0 TolA binding protein trimerisation DUF4763 PF15960.5 ORX88771.1 - 0.12 11.7 11.1 0.027 13.8 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) PRKG1_interact PF15898.5 ORX88771.1 - 0.13 13.2 15.7 0.14 13.0 7.8 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain V-SNARE PF05008.15 ORX88771.1 - 0.14 12.5 7.0 0.63 10.5 7.0 2.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus OmpH PF03938.14 ORX88771.1 - 0.15 12.4 20.6 0.037 14.4 14.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Allexi_40kDa PF05549.11 ORX88771.1 - 0.16 11.4 5.3 0.24 10.9 4.5 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Nup88 PF10168.9 ORX88771.1 - 0.16 9.7 8.4 0.28 8.9 8.4 1.3 1 0 0 1 1 1 0 Nuclear pore component Exonuc_VII_L PF02601.15 ORX88771.1 - 0.19 11.3 14.7 0.94 9.0 14.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 ORX88771.1 - 0.21 11.0 19.0 0.017 14.6 11.3 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 ORX88771.1 - 0.24 10.7 19.5 0.28 10.5 12.4 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 ORX88771.1 - 0.26 10.9 19.8 0.025 14.2 10.8 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FUSC PF04632.12 ORX88771.1 - 0.27 9.7 1.6 0.41 9.1 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 ORX88771.1 - 0.28 11.2 2.3 0.78 9.8 2.0 1.9 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 ORX88771.1 - 0.31 10.0 16.3 0.13 11.2 11.3 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FapA PF03961.13 ORX88771.1 - 0.47 9.0 9.5 0.23 10.0 6.0 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A HMMR_N PF15905.5 ORX88771.1 - 0.47 9.9 16.7 0.86 9.0 16.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal LMBR1 PF04791.16 ORX88771.1 - 0.52 9.1 4.5 0.79 8.6 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HrpB7 PF09486.10 ORX88771.1 - 0.54 10.6 8.9 1.7 9.0 2.6 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 ORX88771.1 - 0.54 10.0 18.0 0.41 10.3 12.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) MscS_porin PF12795.7 ORX88771.1 - 0.56 9.7 21.4 0.11 12.0 14.3 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Uds1 PF15456.6 ORX88771.1 - 0.87 9.8 10.1 1.5 9.0 4.4 2.8 2 1 0 2 2 2 0 Up-regulated During Septation Fez1 PF06818.15 ORX88771.1 - 0.9 10.0 15.2 2.3 8.6 15.2 1.7 1 1 0 1 1 1 0 Fez1 Laminin_II PF06009.12 ORX88771.1 - 0.96 9.5 7.8 0.58 10.2 5.4 1.9 2 0 0 2 2 1 0 Laminin Domain II Spc7 PF08317.11 ORX88771.1 - 1.3 7.9 23.2 0.28 10.0 14.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 ORX88771.1 - 1.4 8.2 10.6 0.32 10.3 6.4 1.9 2 0 0 2 2 2 0 FAM76 protein Vps51 PF08700.11 ORX88771.1 - 1.4 9.1 7.1 0.4 10.8 2.2 2.7 2 1 1 3 3 1 0 Vps51/Vps67 FlaC_arch PF05377.11 ORX88771.1 - 1.5 9.3 12.9 1.8 9.0 1.0 4.0 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) HBM PF16591.5 ORX88771.1 - 1.6 8.1 11.7 0.99 8.8 5.9 2.3 1 1 1 2 2 2 0 Helical bimodular sensor domain CC2-LZ PF16516.5 ORX88771.1 - 1.8 9.0 18.8 3.8 7.9 7.0 3.6 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF812 PF05667.11 ORX88771.1 - 2 7.2 20.4 0.29 10.0 11.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF812) MAD PF05557.13 ORX88771.1 - 2 6.7 22.6 10 4.3 22.7 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein YscO PF07321.12 ORX88771.1 - 2.2 8.2 19.5 1.5 8.8 8.8 2.6 2 0 0 2 2 2 0 Type III secretion protein YscO Fib_alpha PF08702.10 ORX88771.1 - 2.3 8.4 16.6 14 5.9 0.5 2.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family BORCS7 PF16088.5 ORX88771.1 - 2.3 8.5 9.1 4.7 7.5 8.0 2.2 2 0 0 2 2 1 0 BLOC-1-related complex sub-unit 7 DUF489 PF04356.12 ORX88771.1 - 2.5 8.1 6.9 1.8 8.5 3.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF489) USP8_interact PF08941.10 ORX88771.1 - 3.1 7.6 8.1 1.7 8.4 3.7 2.4 2 0 0 2 2 2 0 USP8 interacting ApoLp-III PF07464.11 ORX88771.1 - 3.3 7.8 15.9 3.7 7.6 14.7 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Retrotrans_gag PF03732.17 ORX88771.1 - 3.3 8.0 7.4 1.3 9.4 1.4 2.7 3 0 0 3 3 2 0 Retrotransposon gag protein Phage_GP20 PF06810.11 ORX88771.1 - 4 7.2 16.8 1.1 9.1 9.8 2.7 3 0 0 3 3 2 0 Phage minor structural protein GP20 T3SSipB PF16535.5 ORX88771.1 - 4.2 7.8 11.5 0.24 11.9 5.5 1.9 2 0 0 2 2 1 0 Type III cell invasion protein SipB YabA PF06156.13 ORX88771.1 - 4.3 8.0 16.1 0.6 10.8 0.5 3.0 2 1 0 2 2 2 0 Initiation control protein YabA FAM184 PF15665.5 ORX88771.1 - 4.9 6.9 19.5 5.1 6.8 1.9 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF2203 PF09969.9 ORX88771.1 - 5.8 7.7 11.0 16 6.2 6.8 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA_23 PF13476.6 ORX88771.1 - 7.2 7.1 12.0 1.2 9.6 7.5 1.9 2 0 0 2 2 1 0 AAA domain kleA_kleC PF17383.2 ORX88771.1 - 8 6.9 6.8 6.3 7.2 1.0 2.5 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A FliJ PF02050.16 ORX88771.1 - 9.6 6.5 22.2 0.62 10.3 9.4 2.8 3 0 0 3 3 2 0 Flagellar FliJ protein ELFV_dehydrog PF00208.21 ORX88772.1 - 7.5e-57 192.8 1.5 1e-55 189.1 0.4 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORX88772.1 - 5.7e-56 188.0 0.0 9.9e-56 187.2 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TRL PF13146.6 ORX88772.1 - 0.0088 16.3 0.0 2 8.7 0.1 2.4 2 0 0 2 2 2 1 TRL-like protein family NAD_binding_7 PF13241.6 ORX88772.1 - 0.017 15.5 0.1 0.037 14.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Bac_GDH PF05088.12 ORX88772.1 - 0.035 11.6 0.0 0.056 10.9 0.0 1.4 1 1 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase 2-Hacid_dh_C PF02826.19 ORX88772.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBM_21 PF03370.13 ORX88773.1 - 3.9e-29 101.1 1.5 8.6e-29 100.0 1.5 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORX88773.1 - 1.6e-10 41.4 1.6 1.6e-10 41.4 1.6 2.3 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) CBM_25 PF03423.13 ORX88773.1 - 0.14 12.4 0.7 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) DUF4764 PF15961.5 ORX88773.1 - 2.3 6.8 11.4 0.53 8.9 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) BK_channel_a PF03493.18 ORX88774.1 - 8e-20 70.9 0.0 5.9e-18 64.9 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORX88774.1 - 1.2e-12 47.6 7.9 4e-12 45.9 7.9 1.9 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 ORX88774.1 - 0.0052 17.0 0.0 6.4 7.1 0.0 2.9 3 0 0 3 3 3 2 TrkA-N domain Ion_trans PF00520.31 ORX88774.1 - 0.35 10.1 21.8 0.7 9.1 21.8 1.5 1 0 0 1 1 1 0 Ion transport protein Lig_chan PF00060.26 ORX88774.1 - 4.2 7.2 6.8 0.22 11.3 0.8 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel NAD_binding_1 PF00175.21 ORX88775.1 - 1.4e-30 106.1 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORX88775.1 - 1.6e-20 73.3 0.0 3.3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORX88775.1 - 5.1e-09 36.4 0.0 6.4e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Adaptin_N PF01602.20 ORX88776.1 - 1.3e-118 396.9 6.1 1.8e-118 396.4 6.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 ORX88776.1 - 2.9e-58 196.3 2.4 2.9e-58 196.3 2.4 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 ORX88776.1 - 5e-37 126.5 0.3 1.5e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 ORX88776.1 - 3e-19 69.2 0.1 1.9e-10 41.0 0.0 4.8 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 ORX88776.1 - 2.4e-05 24.2 6.9 0.73 10.3 0.1 6.0 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 ORX88776.1 - 0.00029 20.9 11.7 0.95 9.5 0.1 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORX88776.1 - 0.00076 19.9 0.7 0.012 16.0 0.1 3.0 2 1 0 2 2 2 1 HEAT-like repeat DUF5578 PF17741.1 ORX88776.1 - 0.0046 16.4 1.2 0.19 11.1 0.2 3.4 2 1 1 3 3 3 1 Family of unknown function (DUF5578) Arm PF00514.23 ORX88776.1 - 0.0071 16.4 1.4 12 6.1 0.1 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 ORX88776.1 - 0.0079 16.8 4.4 2.3 9.2 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat DUF1435 PF07256.12 ORX88778.1 - 0.26 11.4 13.5 0.7 10.0 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) HECT_2 PF09814.9 ORX88779.1 - 1.2e-50 172.5 1.5 1.4e-50 172.3 1.5 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 ORX88779.1 - 0.15 12.3 1.4 1.9 8.7 1.7 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RRM_1 PF00076.22 ORX88780.1 - 5e-19 67.9 0.0 9e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX88780.1 - 5.8e-05 23.1 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 ORX88780.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 ORX88780.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Rota_VP2 PF05087.12 ORX88780.1 - 0.22 9.6 0.0 0.22 9.6 0.0 2.1 2 0 0 2 2 2 0 Rotavirus VP2 protein PhoLip_ATPase_C PF16212.5 ORX88782.1 - 9e-89 297.5 23.0 9e-89 297.5 23.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX88782.1 - 8.3e-23 79.9 6.4 1.8e-22 78.8 6.4 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORX88782.1 - 6.8e-12 46.1 0.0 5.4e-07 30.1 0.0 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX88782.1 - 2.9e-10 40.1 0.0 8.9e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX88782.1 - 1.1e-06 28.3 0.0 3e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORX88782.1 - 0.007 16.1 0.1 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PACT_coil_coil PF10495.9 ORX88782.1 - 0.14 12.8 0.1 0.41 11.3 0.1 1.8 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein WSC PF01822.19 ORX88783.1 - 2.8e-18 65.9 7.8 5.2e-18 65.0 7.8 1.4 1 1 0 1 1 1 1 WSC domain DHHA2 PF02833.14 ORX88784.1 - 1.6e-35 122.4 0.0 2.5e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 ORX88784.1 - 3.3e-06 27.2 0.7 1.5e-05 25.2 0.7 1.9 1 1 0 1 1 1 1 DHH family FHA_2 PF17913.1 ORX88784.1 - 0.024 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 FHA domain BING4CT PF08149.11 ORX88785.1 - 3e-41 139.1 0.1 1.2e-37 127.6 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 ORX88785.1 - 1.7e-07 31.8 4.0 0.00017 22.3 0.0 5.4 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX88785.1 - 2e-07 31.2 0.1 2 8.7 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX88785.1 - 0.00019 21.4 0.1 0.76 9.6 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 ORX88785.1 - 0.0002 20.6 0.1 0.00049 19.3 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region Arylesterase PF01731.20 ORX88785.1 - 0.09 13.0 0.4 0.19 11.9 0.4 1.5 1 0 0 1 1 1 0 Arylesterase WD40_like PF17005.5 ORX88785.1 - 0.11 11.8 0.1 0.63 9.3 0.1 1.7 1 1 0 1 1 1 0 WD40-like domain Nup54 PF13874.6 ORX88786.1 - 4.8e-44 149.9 9.8 4.8e-44 149.9 9.8 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 ORX88786.1 - 0.0011 18.8 0.5 0.0031 17.4 0.5 1.7 1 0 0 1 1 1 1 Nup54 C-terminal interacting domain P_proprotein PF01483.20 ORX88786.1 - 0.017 15.1 0.3 0.14 12.2 0.3 2.2 1 1 0 1 1 1 0 Proprotein convertase P-domain MerR_1 PF13411.6 ORX88786.1 - 0.049 13.7 0.5 5.9 7.1 0.0 2.5 2 1 0 2 2 2 0 MerR HTH family regulatory protein SPRY PF00622.28 ORX88787.1 - 3.8e-18 65.7 0.0 6.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain SPRY PF00622.28 ORX88788.1 - 8.9e-20 71.0 0.0 1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 SPRY domain DUF1883 PF08980.10 ORX88788.1 - 0.056 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) SPRY PF00622.28 ORX88789.1 - 4.4e-16 59.1 0.1 5.2e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 SPRY domain Peptidase_M14 PF00246.24 ORX88790.1 - 5.7e-78 262.7 0.7 7.2e-78 262.3 0.7 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORX88790.1 - 0.057 13.8 3.9 0.12 12.8 2.5 2.3 2 1 0 2 2 2 0 Carboxypeptidase activation peptide NAGLU PF05089.12 ORX88791.1 - 2e-111 372.2 8.4 3e-111 371.6 8.4 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 ORX88791.1 - 1.9e-57 194.8 3.1 3.5e-48 164.5 0.3 2.9 2 1 1 3 3 3 2 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 ORX88791.1 - 1.2e-09 37.8 0.2 3.4e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain CBAH PF02275.18 ORX88792.1 - 0.0056 16.4 0.2 0.0079 15.9 0.2 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Enkurin PF13864.6 ORX88792.1 - 0.99 9.9 7.5 2 8.9 7.5 1.5 1 1 0 1 1 1 0 Calmodulin-binding Kelch_4 PF13418.6 ORX88794.1 - 0.001 19.0 0.2 3.3 7.8 0.0 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 ORX88794.1 - 0.0014 18.9 0.6 6.4 7.2 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORX88794.1 - 0.0027 17.7 1.3 1.9 8.6 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 ORX88794.1 - 0.0038 17.5 2.4 9 6.8 0.1 3.6 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 ORX88794.1 - 0.018 15.0 0.0 19 5.5 0.0 3.2 3 0 0 3 3 3 0 Kelch motif HAUS5 PF14817.6 ORX88795.1 - 2.6e-13 49.6 13.8 5.1e-11 42.1 8.1 2.3 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 5 SAM_Exu PF18609.1 ORX88795.1 - 0.036 14.2 0.6 0.55 10.4 0.0 2.9 3 0 0 3 3 3 0 Exuperantia SAM-like domain Baculo_PEP_C PF04513.12 ORX88795.1 - 0.15 12.1 6.8 0.074 13.1 0.7 3.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 ORX88795.1 - 0.73 10.4 10.7 8.8 6.9 1.0 4.4 2 2 3 5 5 5 0 Spectrin repeat DUF1043 PF06295.12 ORX88795.1 - 0.89 9.6 8.5 0.36 10.8 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Med9 PF07544.13 ORX88795.1 - 3.1 7.9 17.9 3.1 8.0 4.3 4.4 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 SRA1 PF07304.11 ORX88797.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) CBAH PF02275.18 ORX88798.1 - 0.0029 17.3 0.3 0.0041 16.8 0.3 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF1180 PF06679.12 ORX88799.1 - 3.3 8.1 5.3 4.6 7.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ABC2_membrane PF01061.24 ORX88800.1 - 2.2e-47 161.2 20.6 2.2e-47 161.2 20.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORX88800.1 - 9.4e-25 87.7 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX88800.1 - 1.9e-06 27.2 25.8 1.9e-06 27.2 25.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX88800.1 - 0.00025 20.9 0.7 0.089 12.6 0.4 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 ORX88800.1 - 0.00029 20.2 11.8 0.00029 20.2 11.8 2.0 2 1 1 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX88800.1 - 0.0014 18.6 0.2 0.0034 17.3 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ORX88800.1 - 0.0014 18.1 0.5 0.67 9.4 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX88800.1 - 0.0075 16.7 0.3 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ORX88800.1 - 0.0098 16.4 0.6 0.0098 16.4 0.6 2.1 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 ORX88800.1 - 0.024 14.2 0.1 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORX88800.1 - 0.043 13.6 0.8 0.11 12.3 0.8 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORX88800.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORX88800.1 - 0.065 13.5 0.9 1.6 9.0 0.5 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORX88800.1 - 0.11 12.8 0.3 0.98 9.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORX88800.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Pkinase PF00069.25 ORX88801.1 - 2.4e-25 89.4 0.0 3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88801.1 - 5.7e-12 45.5 0.0 7.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX88801.1 - 1.1e-05 24.4 0.1 1.1e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX88801.1 - 0.043 13.7 0.0 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RNA12 PF10443.9 ORX88802.1 - 2.2e-115 385.9 0.9 4.4e-65 220.2 0.1 2.1 1 1 1 2 2 2 2 RNA12 protein RRM_1 PF00076.22 ORX88802.1 - 7.3e-07 28.9 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 ORX88802.1 - 0.00013 22.0 0.2 0.00045 20.2 0.2 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ORX88802.1 - 0.00075 19.9 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 ORX88802.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Mem_trans PF03547.18 ORX88803.1 - 9.9e-33 113.1 20.4 3.9e-17 61.7 5.6 2.1 1 1 0 2 2 2 2 Membrane transport protein RasGAP PF00616.19 ORX88804.1 - 3.4e-17 62.9 0.3 1.1e-16 61.2 0.0 2.3 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RPW8 PF05659.11 ORX88804.1 - 0.025 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LacAB_rpiB PF02502.18 ORX88804.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Pan3_PK PF18101.1 ORX88804.1 - 0.044 13.8 0.4 1.1 9.3 0.1 2.7 2 1 1 3 3 3 0 Pan3 Pseudokinase domain TMEM82 PF15816.5 ORX88804.1 - 0.045 12.7 0.0 0.17 10.8 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 82 zf-CDGSH PF09360.10 ORX88806.1 - 6e-13 48.8 8.1 4.5e-07 30.0 3.3 2.6 2 1 0 2 2 2 2 Iron-binding zinc finger CDGSH type Ribosomal_S5 PF00333.20 ORX88807.1 - 1.9e-28 98.2 0.4 1.9e-28 98.2 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX88807.1 - 5.2e-26 89.9 0.1 8.5e-26 89.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORX88807.1 - 0.69 10.5 11.2 1.3 9.6 11.2 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FSH1 PF03959.13 ORX88808.1 - 2e-49 168.2 0.0 2.2e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORX88808.1 - 0.23 11.2 0.2 1.1 9.0 0.2 1.9 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase LRR_6 PF13516.6 ORX88809.1 - 4.1e-11 42.0 8.2 0.17 12.0 0.0 7.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 ORX88809.1 - 7.9e-11 42.0 6.0 0.36 11.3 0.5 6.9 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX88809.1 - 0.0058 17.0 9.4 4.5 8.2 0.0 6.8 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 ORX88809.1 - 0.09 12.6 1.4 44 3.9 0.2 4.5 7 1 0 7 7 7 0 Leucine rich repeat Yos1 PF08571.10 ORX88810.1 - 2.3e-32 111.1 0.9 2.6e-32 110.9 0.9 1.0 1 0 0 1 1 1 1 Yos1-like PAP2_3 PF14378.6 ORX88812.1 - 1.2e-23 83.8 6.8 1.2e-23 83.8 6.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ORX88812.1 - 4.5e-10 39.4 4.2 4.5e-10 39.4 4.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF563 PF04577.14 ORX88813.1 - 5.1e-24 85.6 0.4 1e-23 84.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) GPI-anchored PF10342.9 ORX88818.1 - 0.00073 20.2 0.1 0.0014 19.3 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Imm21 PF15589.6 ORX88818.1 - 0.038 14.0 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 21 GBS_Bsp-like PF08481.10 ORX88818.1 - 0.11 12.6 0.0 0.73 10.0 0.1 1.9 1 1 0 1 1 1 0 GBS Bsp-like repeat Microtub_bind PF13931.6 ORX88819.1 - 0.14 12.5 0.1 0.2 12.1 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Peripla_BP_2 PF01497.18 ORX88820.1 - 0.032 13.8 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Anophelin PF10731.9 ORX88820.1 - 0.066 13.1 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF3472 PF11958.8 ORX88821.1 - 2.4e-11 44.4 0.0 4.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX88821.1 - 1.5e-05 25.0 0.0 3.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF1461 PF07314.11 ORX88821.1 - 0.15 11.9 1.5 0.31 10.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) 2HCT PF03390.15 ORX88822.1 - 0.25 9.9 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family ArfGap PF01412.18 ORX88823.1 - 1.2e-31 109.2 1.6 1.8e-31 108.7 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Tetraspanin PF00335.20 ORX88824.1 - 2.9e-14 53.4 13.8 3.4e-14 53.1 13.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Pex24p PF06398.11 ORX88824.1 - 7.1 5.5 8.8 14 4.6 8.8 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin ABC2_membrane PF01061.24 ORX88825.1 - 7.9e-92 306.4 59.7 2e-47 161.4 27.3 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORX88825.1 - 8.5e-43 146.2 0.0 4.1e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORX88825.1 - 3.1e-25 87.9 1.2 2.6e-19 68.9 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX88825.1 - 9.6e-09 35.7 0.0 2.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 ORX88825.1 - 6e-07 29.6 0.1 0.002 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORX88825.1 - 7.2e-07 29.3 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORX88825.1 - 1.4e-05 25.6 0.3 0.0026 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORX88825.1 - 5.2e-05 23.8 1.2 0.022 15.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 ORX88825.1 - 5.3e-05 22.9 0.0 0.00059 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORX88825.1 - 0.00024 20.8 0.1 0.034 13.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX88825.1 - 0.00051 20.1 0.1 1.9 8.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 ORX88825.1 - 0.00052 20.2 0.1 0.2 11.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 ORX88825.1 - 0.0008 19.8 0.1 1.5 9.3 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORX88825.1 - 0.0019 18.4 0.1 0.032 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX88825.1 - 0.0022 18.3 0.0 1.3 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX88825.1 - 0.0045 16.7 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORX88825.1 - 0.0065 15.8 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 ORX88825.1 - 0.0079 16.1 0.1 0.52 10.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain PDR_assoc PF08370.11 ORX88825.1 - 0.017 14.9 0.2 0.017 14.9 0.2 5.3 6 0 0 6 6 5 0 Plant PDR ABC transporter associated SMC_N PF02463.19 ORX88825.1 - 0.017 14.6 0.1 0.06 12.8 0.1 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 ORX88825.1 - 0.026 14.1 0.1 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 ORX88825.1 - 0.062 13.2 0.1 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 ORX88825.1 - 0.087 12.6 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 ORX88825.1 - 0.19 10.8 49.4 0.0063 15.7 13.7 3.1 2 2 0 2 2 2 0 ABC-2 family transporter protein TsaE PF02367.17 ORX88825.1 - 0.19 11.7 0.7 0.52 10.3 0.2 2.0 2 1 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORX88825.1 - 0.19 11.4 0.2 2.8 7.6 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein ABC2_membrane_2 PF12679.7 ORX88825.1 - 0.66 9.2 19.8 0.86 8.8 8.0 2.7 2 0 0 2 2 2 0 ABC-2 family transporter protein V-SNARE_C PF12352.8 ORX88826.1 - 2.5e-05 24.5 8.6 0.0031 17.8 1.0 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus CagX PF03524.15 ORX88826.1 - 0.053 13.2 1.0 0.1 12.3 1.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein DUF1359 PF07097.11 ORX88826.1 - 1.4 9.2 6.7 0.39 11.0 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) Phosducin PF02114.16 ORX88827.1 - 3.3e-07 29.5 0.8 4e-07 29.2 0.8 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 ORX88827.1 - 1.5e-05 24.9 0.1 3.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2852 PF11014.8 ORX88827.1 - 0.12 12.5 1.3 0.2 11.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) zf-C3HC4_3 PF13920.6 ORX88828.1 - 8.5e-13 47.9 5.1 1.5e-12 47.2 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GIDE PF12483.8 ORX88828.1 - 1.3e-12 47.4 0.0 1.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 E3 Ubiquitin ligase Prok-RING_4 PF14447.6 ORX88828.1 - 0.00013 21.7 6.5 0.0003 20.6 6.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORX88828.1 - 0.0015 18.4 7.6 0.0015 18.4 7.6 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORX88828.1 - 0.0043 17.4 8.1 0.0043 17.4 8.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX88828.1 - 0.01 15.7 8.7 0.01 15.7 8.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 ORX88828.1 - 0.035 13.8 4.5 0.072 12.8 4.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 ORX88828.1 - 0.13 12.0 1.5 0.24 11.2 0.5 1.9 2 0 0 2 2 2 0 RING-like zinc finger ArfGap PF01412.18 ORX88829.1 - 8.7e-33 112.9 0.8 8.7e-33 112.9 0.8 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 ORX88829.1 - 4e-16 59.4 10.3 4.6e-16 59.3 8.6 1.9 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORX88829.1 - 1e-10 42.0 0.1 2.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 PH domain Syntaxin_2 PF14523.6 ORX88829.1 - 0.016 15.6 4.6 0.073 13.5 0.1 3.0 2 0 0 2 2 2 0 Syntaxin-like protein Sec20 PF03908.13 ORX88829.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.6 3 0 0 3 3 3 0 Sec20 RRF PF01765.19 ORX88829.1 - 0.84 9.6 5.2 11 6.0 0.1 2.7 2 1 0 2 2 2 0 Ribosome recycling factor NUDIX PF00293.28 ORX88830.1 - 3.5e-11 43.3 0.0 6.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DNA_PPF PF02916.15 ORX88830.1 - 0.021 15.2 0.0 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase processivity factor V-ATPase_H_N PF03224.14 ORX88831.1 - 3.2e-91 305.9 6.7 3.2e-91 305.9 6.7 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORX88831.1 - 6.5e-48 161.7 5.0 3e-46 156.3 0.0 3.8 2 1 2 5 5 5 1 V-ATPase subunit H Arm PF00514.23 ORX88831.1 - 2.6e-06 27.3 0.0 2.2 8.4 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 ORX88831.1 - 0.0042 16.6 5.0 0.0042 16.6 0.0 2.6 2 1 0 2 2 2 1 Armadillo-like CTNNBL PF08216.11 ORX88831.1 - 0.0048 17.0 0.3 2.5 8.3 0.0 3.0 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear HEAT PF02985.22 ORX88831.1 - 0.0059 16.8 0.1 0.058 13.7 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 ORX88831.1 - 0.039 14.3 0.0 0.31 11.5 0.0 2.5 3 0 0 3 3 3 0 HEAT repeats DUF3385 PF11865.8 ORX88831.1 - 0.067 13.1 2.0 0.39 10.6 2.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) DDE_3 PF13358.6 ORX88831.1 - 0.11 12.2 1.2 29 4.4 0.0 3.1 3 0 0 3 3 3 0 DDE superfamily endonuclease PAP2 PF01569.21 ORX88832.1 - 4.3e-16 58.9 3.5 1.3e-15 57.3 3.5 1.8 1 0 0 1 1 1 1 PAP2 superfamily DUF1440 PF07274.12 ORX88832.1 - 0.023 15.0 4.7 0.051 13.9 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) LptF_LptG PF03739.14 ORX88832.1 - 2.3 7.0 6.5 3.8 6.2 6.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RRM_1 PF00076.22 ORX88833.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.22 ORX88833.1 - 0.87 8.7 8.9 1.1 8.4 8.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S9_N PF02897.15 ORX88834.1 - 4.5e-60 203.6 1.7 6.4e-60 203.1 1.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORX88834.1 - 2.6e-50 170.8 0.0 4.3e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORX88834.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PTPS PF01242.19 ORX88835.1 - 2.2e-34 118.1 0.5 2.4e-34 117.9 0.5 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase CBM26 PF16738.5 ORX88835.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Starch-binding module 26 DUF1729 PF08354.10 ORX88836.1 - 1.1e-152 508.0 0.0 2.8e-152 506.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ORX88836.1 - 1.5e-72 244.8 0.3 1.9e-71 241.2 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain FAS_I_H PF18314.1 ORX88836.1 - 1.7e-71 240.1 1.2 3.1e-71 239.2 0.2 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 ORX88836.1 - 5.1e-69 231.8 0.0 9.9e-69 230.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 ORX88836.1 - 1.1e-39 135.6 0.1 2.5e-39 134.4 0.1 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 ORX88836.1 - 3.7e-30 104.0 0.1 1.4e-29 102.2 0.1 2.0 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 ORX88836.1 - 1.1e-28 100.6 0.0 5.4e-28 98.3 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 ORX88836.1 - 2e-28 98.9 3.8 2.5e-28 98.7 0.6 2.5 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 ORX88836.1 - 5.3e-20 72.1 0.6 2.1e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydrat_N PF13452.6 ORX88836.1 - 1e-13 51.5 0.0 2.9e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Ketoacyl-synt_C PF02801.22 ORX88836.1 - 2.3e-13 50.2 0.0 5.7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 ORX88836.1 - 1.9e-07 31.2 0.1 8.9e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 ORX88836.1 - 0.0001 21.8 0.0 0.00034 20.1 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase HEPN_AbiV PF18728.1 ORX88836.1 - 5.1 7.2 5.8 4.7 7.3 0.1 3.2 3 0 0 3 3 3 0 AbiV Sulfate_transp PF00916.20 ORX88837.1 - 1.6e-90 303.6 19.6 2.2e-90 303.2 19.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX88837.1 - 8.3e-17 60.9 0.0 1.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORX88837.1 - 0.0022 18.4 6.5 0.0022 18.4 6.5 3.5 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORX88837.1 - 0.042 14.2 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 STAS domain Myc_target_1 PF15179.6 ORX88837.1 - 0.28 11.1 0.1 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Myc target protein 1 DUF5367 PF17329.2 ORX88837.1 - 0.7 10.1 5.3 14 5.9 0.7 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5367) Peroxidase_2 PF01328.17 ORX88838.1 - 7.8e-49 166.7 0.0 9.4e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DEAD PF00270.29 ORX88839.1 - 1.6e-48 164.8 0.0 2.4e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX88839.1 - 1.9e-31 108.7 0.2 8.6e-31 106.6 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX88839.1 - 1.7e-05 24.9 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORX88839.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 ORX88840.1 - 2e-26 92.0 0.1 2.3e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORX88840.1 - 9.6e-06 25.1 0.1 1.2e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORX88840.1 - 4e-05 23.9 0.2 0.0013 19.0 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORX88840.1 - 0.00032 21.1 0.2 0.00067 20.1 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORX88840.1 - 0.00045 20.4 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 ORX88840.1 - 0.0025 17.7 0.1 0.0029 17.4 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 ORX88840.1 - 0.0036 17.2 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 ORX88840.1 - 0.0057 16.4 0.1 0.014 15.1 0.0 1.5 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 ORX88840.1 - 0.01 15.8 0.1 0.015 15.2 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family QRPTase_C PF01729.19 ORX88841.1 - 1.1e-55 188.0 0.2 1.4e-55 187.7 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ORX88841.1 - 3.4e-19 68.7 0.0 1.1e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.21 ORX88841.1 - 0.13 11.4 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Tctex-1 PF03645.13 ORX88842.1 - 5.3e-26 90.8 0.3 5.9e-26 90.7 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M14 PF00246.24 ORX88844.1 - 4e-80 269.7 0.1 4.5e-80 269.6 0.1 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase EF-hand_1 PF00036.32 ORX88845.1 - 5.3e-22 75.7 10.8 1e-06 27.9 0.1 4.8 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX88845.1 - 1.8e-19 70.0 1.8 2.1e-10 40.9 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORX88845.1 - 4.9e-18 63.5 6.2 4.4e-07 29.3 0.1 4.1 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORX88845.1 - 1.7e-16 59.8 0.8 1e-05 25.3 0.0 3.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORX88845.1 - 1.3e-11 43.4 3.9 0.0018 17.7 0.0 3.6 4 0 0 4 4 4 3 EF hand Caleosin PF05042.13 ORX88845.1 - 0.003 17.5 0.8 0.89 9.5 0.0 3.2 1 1 3 4 4 4 1 Caleosin related protein EF-hand_9 PF14658.6 ORX88845.1 - 0.0034 17.7 0.0 0.072 13.4 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain GGDEF_2 PF17853.1 ORX88845.1 - 0.23 11.7 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 GGDEF-like domain RPA43_OB PF17875.1 ORX88846.1 - 4.3e-17 62.9 0.1 4.3e-17 62.9 0.1 3.3 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 ORX88846.1 - 3.1e-11 43.5 0.0 5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Coilin_N PF15862.5 ORX88846.1 - 6.5 6.6 11.3 0.67 9.8 1.5 2.4 2 0 0 2 2 2 0 Coilin N-terminus AA_permease PF00324.21 ORX88847.1 - 4.8e-69 233.2 36.0 6e-69 232.9 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 ORX88847.1 - 7.7e-24 84.5 1.6 4.4e-12 45.8 0.1 3.5 4 0 0 4 4 4 3 Solute carrier family 12 AA_permease_2 PF13520.6 ORX88847.1 - 7.8e-19 67.8 42.2 1.2e-18 67.2 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5389 PF17364.2 ORX88847.1 - 0.11 12.6 0.8 5.8 7.0 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5389) PPR_2 PF13041.6 ORX88848.1 - 2.9e-113 370.0 30.3 3.2e-16 59.2 0.0 14.1 4 2 11 15 15 15 13 PPR repeat family PPR_1 PF12854.7 ORX88848.1 - 9.7e-94 306.7 6.5 3.5e-09 36.2 0.0 14.9 15 0 0 15 15 15 14 PPR repeat PPR PF01535.20 ORX88848.1 - 6.6e-91 292.4 10.8 1.5e-07 31.2 0.0 15.7 15 1 0 15 15 15 13 PPR repeat PPR_3 PF13812.6 ORX88848.1 - 6.7e-65 215.1 14.2 4.2e-10 39.5 0.0 9.4 5 4 3 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX88848.1 - 1.5e-37 129.0 0.4 1.8e-10 40.5 0.3 5.1 1 1 4 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 ORX88848.1 - 1.5e-10 41.4 0.1 0.015 15.8 0.0 6.4 7 1 1 8 8 7 3 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX88848.1 - 1.2e-09 37.6 1.9 0.032 13.1 0.0 5.4 4 2 0 6 6 6 2 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 ORX88848.1 - 6e-09 35.8 0.9 0.0071 16.2 0.0 5.4 4 3 1 5 5 4 2 Mitochondrial ATPase expression TPR_14 PF13428.6 ORX88848.1 - 6.1e-09 36.0 0.4 4.2 8.5 0.0 9.1 6 3 4 10 10 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX88848.1 - 2.6e-08 33.3 3.2 0.0062 16.3 0.0 7.1 9 0 0 9 9 7 1 Tetratricopeptide repeat Clathrin PF00637.20 ORX88848.1 - 2.3e-07 30.8 4.3 0.35 10.7 0.1 6.2 3 1 4 7 7 6 2 Region in Clathrin and VPS TPR_7 PF13176.6 ORX88848.1 - 2.5e-07 30.2 0.8 0.81 9.9 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX88848.1 - 8e-06 26.1 4.3 0.66 10.3 0.0 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat Gln-synt_C-ter PF18318.1 ORX88848.1 - 5e-05 23.1 0.7 0.77 9.6 0.0 4.1 3 1 1 4 4 4 2 Glutamine synthetase C-terminal domain BTAD PF03704.17 ORX88848.1 - 6.2e-05 23.5 0.7 0.0029 18.0 0.2 3.3 4 0 0 4 4 2 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 ORX88848.1 - 0.00019 22.0 0.3 3.7 8.3 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat RPM2 PF08579.11 ORX88848.1 - 0.0003 21.2 8.1 2.8 8.4 0.1 5.3 3 3 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) RPN7 PF10602.9 ORX88848.1 - 0.0014 18.3 0.1 27 4.4 0.0 5.4 4 2 0 4 4 4 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 ORX88848.1 - 0.002 18.1 10.0 0.66 10.2 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Vps23_core PF09454.10 ORX88848.1 - 0.0083 16.1 2.5 11 6.1 0.2 4.5 3 1 2 5 5 3 0 Vps23 core domain Prp18 PF02840.15 ORX88848.1 - 0.021 14.9 0.6 0.9 9.6 0.0 3.2 3 0 0 3 3 3 0 Prp18 domain TPR_6 PF13174.6 ORX88848.1 - 0.024 15.3 2.8 77 4.2 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat DED PF01335.21 ORX88848.1 - 0.028 14.7 0.5 15 6.0 0.0 4.3 4 1 0 4 4 3 0 Death effector domain Fer2_2 PF01799.20 ORX88848.1 - 0.06 13.4 0.3 0.39 10.8 0.1 2.5 2 1 0 2 2 2 0 [2Fe-2S] binding domain TPR_17 PF13431.6 ORX88848.1 - 0.13 12.6 0.1 3.8 8.1 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORX88848.1 - 0.24 11.7 2.2 40 4.6 0.1 5.0 4 2 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 PNP_UDP_1 PF01048.20 ORX88849.1 - 9.9e-36 123.2 0.0 1.2e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily N2227 PF07942.12 ORX88850.1 - 1.7e-100 335.7 0.0 2.4e-100 335.2 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 ORX88850.1 - 0.00079 20.1 0.0 0.0036 18.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX88850.1 - 0.026 14.3 0.1 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORX88850.1 - 0.13 13.0 0.0 2 9.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain PMT PF02366.18 ORX88851.1 - 2.2e-84 282.9 15.3 2.2e-84 282.9 15.3 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX88851.1 - 1.9e-66 223.4 15.5 1.9e-66 223.4 15.5 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX88851.1 - 5.6e-32 111.1 0.8 9.8e-32 110.3 0.8 1.3 1 0 0 1 1 1 1 MIR domain DUF2516 PF10724.9 ORX88851.1 - 3.6 8.0 12.6 1.9 8.8 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2516) Peptidase_M14 PF00246.24 ORX88852.1 - 1e-80 271.6 0.0 1.2e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase UEV PF05743.13 ORX88853.1 - 0.06 13.2 0.1 0.076 12.9 0.1 1.2 1 0 0 1 1 1 0 UEV domain Gcw_chp PF09694.10 ORX88853.1 - 0.18 11.7 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) Peptidase_S8 PF00082.22 ORX88854.1 - 9.7e-35 120.3 13.6 1.9e-34 119.3 13.6 1.4 1 1 0 1 1 1 1 Subtilase family TPP_enzyme_N PF02776.18 ORX88854.1 - 7.4e-05 22.4 2.8 0.00025 20.7 0.3 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peripla_BP_4 PF13407.6 ORX88854.1 - 0.017 14.7 0.2 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain Inhibitor_I9 PF05922.16 ORX88854.1 - 0.024 15.3 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF2478 PF10649.9 ORX88854.1 - 0.16 11.6 0.4 7.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) His_Phos_2 PF00328.22 ORX88855.1 - 2.3e-26 93.1 0.0 6.6e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Trp_leader2 PF08056.11 ORX88856.1 - 0.9 9.6 6.4 27 4.8 0.1 4.5 7 0 0 7 7 7 0 Tryptophan operon leader peptide tRNA_edit PF04073.15 ORX88857.1 - 0.0026 17.8 1.3 1.2 9.2 0.1 3.0 1 1 2 3 3 3 2 Aminoacyl-tRNA editing domain He_PIG PF05345.12 ORX88857.1 - 0.084 13.1 8.4 0.99 9.6 0.5 2.7 2 0 0 2 2 2 0 Putative Ig domain Ribosomal_S6e PF01092.19 ORX88861.1 - 1.8e-60 202.4 0.0 3.6e-60 201.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Lebercilin PF15619.6 ORX88862.1 - 0.01 15.5 17.1 0.01 15.5 17.1 3.8 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 ORX88862.1 - 0.08 13.3 4.5 4.6 7.7 0.2 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) RabGAP-TBC PF00566.18 ORX88863.1 - 1.4e-49 168.7 0.1 1.4e-49 168.7 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 ORX88863.1 - 3.9e-12 46.1 5.7 3.2e-06 27.0 0.3 2.9 3 0 0 3 3 3 2 GRAM domain EF-hand_6 PF13405.6 ORX88863.1 - 5.6e-06 25.9 3.4 0.031 14.2 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORX88863.1 - 0.0013 19.1 6.1 0.0031 17.9 2.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX88863.1 - 0.0082 16.0 0.4 1.4 8.9 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 ORX88863.1 - 0.024 14.1 1.3 0.8 9.4 0.4 2.9 2 0 0 2 2 2 0 EF hand NPA PF16469.5 ORX88863.1 - 0.034 14.7 0.3 0.098 13.2 0.3 1.8 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Lebercilin PF15619.6 ORX88864.1 - 0.0008 19.1 2.9 0.0011 18.6 2.9 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF2312 PF10073.9 ORX88864.1 - 0.12 12.0 0.5 0.21 11.2 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) tRNA_U5-meth_tr PF05958.11 ORX88865.1 - 1e-23 83.9 0.2 1.7e-22 79.9 0.2 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 ORX88865.1 - 9.3e-09 35.2 0.2 2e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX88865.1 - 4.7e-08 33.6 0.1 1.4e-07 32.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 ORX88865.1 - 2.2e-07 30.6 0.1 4.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 ORX88865.1 - 2.4e-07 30.7 0.9 5.7e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 ORX88865.1 - 1.1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX88865.1 - 1.1e-05 25.0 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ORX88865.1 - 2.9e-05 24.6 0.1 8.6e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORX88865.1 - 0.00039 19.9 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltrans_SAM PF10672.9 ORX88865.1 - 0.00082 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PCMT PF01135.19 ORX88865.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 ORX88865.1 - 0.14 12.9 0.1 0.42 11.4 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF4448 PF14610.6 ORX88866.1 - 7.7e-07 29.1 0.1 1.6e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 ORX88866.1 - 0.00051 20.2 0.1 0.00051 20.2 0.1 2.2 2 1 1 3 3 3 1 Podoplanin Rax2 PF12768.7 ORX88866.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VSP PF03302.13 ORX88866.1 - 0.033 13.1 0.1 0.05 12.5 0.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM154 PF15102.6 ORX88866.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family Metallophos PF00149.28 ORX88867.1 - 2.6e-15 57.5 0.2 4.6e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase m_DGTX_Dc1a_b_c PF17491.2 ORX88867.1 - 0.0049 17.5 0.1 1.5 9.5 0.0 3.9 4 0 0 4 4 4 1 Spider Toxins mu-diguetoxin-1 a, b and c Mito_carr PF00153.27 ORX88868.1 - 1.2e-67 223.9 5.3 7.4e-23 80.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORX88868.1 - 1.6e-11 44.5 5.8 3.9e-07 30.4 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX88868.1 - 4.7e-11 41.7 8.2 0.0032 17.3 0.4 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 ORX88868.1 - 8.8e-11 40.6 10.2 0.00032 20.0 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 ORX88868.1 - 2.8e-06 26.6 6.6 0.018 14.5 0.7 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 ORX88868.1 - 3.2e-05 23.7 2.6 0.084 12.7 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX88868.1 - 0.0086 16.4 1.1 3.4 8.0 0.5 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5314 PF17241.2 ORX88868.1 - 0.051 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) EF-hand_4 PF12763.7 ORX88868.1 - 0.16 12.0 1.5 0.48 10.4 0.4 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.27 ORX88869.1 - 1.7e-74 245.9 3.3 1.5e-27 95.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 ORX88869.1 - 0.016 15.3 0.1 13 6.0 0.0 2.9 3 0 0 3 3 3 0 PrcB C-terminal Serine_protease PF18405.1 ORX88869.1 - 2.9 7.0 5.5 11 5.1 0.1 3.4 2 1 0 3 3 3 0 Gammaproteobacterial serine protease GTP_EFTU PF00009.27 ORX88871.1 - 5e-46 156.7 0.0 8e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX88871.1 - 3.7e-15 56.2 0.0 1.2e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX88871.1 - 1.4e-10 41.4 0.7 2.7e-09 37.3 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX88871.1 - 2.5e-05 24.3 0.0 0.011 15.8 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORX88871.1 - 0.00016 21.5 0.3 0.00058 19.7 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 G-alpha PF00503.20 ORX88871.1 - 0.21 10.7 0.3 0.71 9.0 0.1 1.8 1 1 1 2 2 2 0 G-protein alpha subunit CENP-X PF09415.10 ORX88873.1 - 2.1e-21 76.0 0.3 2.5e-21 75.8 0.3 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CarD_CdnL_TRCF PF02559.16 ORX88873.1 - 0.12 13.1 0.0 0.55 11.0 0.0 1.8 2 0 0 2 2 2 0 CarD-like/TRCF domain TFIIA PF03153.13 ORX88874.1 - 1.4 8.8 81.1 4.6 7.1 65.3 2.0 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_S15 PF02129.18 ORX88874.1 - 2.6 7.6 15.7 5.8 6.4 15.7 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) V_ATPase_I PF01496.19 ORX88874.1 - 5 4.9 17.6 7 4.4 17.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Alph_Pro_TM PF09608.10 ORX88874.1 - 8.2 6.2 10.8 14 5.4 10.8 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Lipase_GDSL PF00657.22 ORX88875.1 - 5.5e-05 23.2 0.0 8e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORX88875.1 - 0.00028 21.4 0.0 0.00078 19.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Serpin PF00079.20 ORX88876.1 - 2.7e-39 135.6 1.3 3e-39 135.4 1.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pkinase PF00069.25 ORX88877.1 - 9.9e-73 244.7 0.0 1.2e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88877.1 - 6.6e-37 127.2 0.0 9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX88877.1 - 1.4e-05 24.6 0.1 0.00043 19.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX88877.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORX88877.1 - 0.086 11.6 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 ORX88878.1 - 1.8e-66 220.1 1.4 2e-21 75.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BofC_C PF08955.10 ORX88878.1 - 0.13 12.3 0.1 2.2 8.4 0.0 2.8 3 0 0 3 3 3 0 BofC C-terminal domain Q_salvage PF10343.9 ORX88879.1 - 5.1e-118 393.7 0.1 6.1e-118 393.5 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 ORX88879.1 - 0.08 11.6 0.0 0.46 9.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1688) MFS_5 PF05631.14 ORX88880.1 - 1.2e-83 281.0 8.9 1.7e-83 280.5 8.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ORX88880.1 - 4.2e-13 48.9 62.1 2.3e-12 46.5 41.2 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mpv17_PMP22 PF04117.12 ORX88880.1 - 0.095 12.9 7.0 0.098 12.9 0.6 3.5 3 0 0 3 3 3 0 Mpv17 / PMP22 family MFS_3 PF05977.13 ORX88880.1 - 0.47 8.8 7.0 1.5 7.2 7.0 1.8 1 1 0 1 1 1 0 Transmembrane secretion effector p450 PF00067.22 ORX88881.1 - 4.3e-82 276.3 0.2 5.7e-82 275.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Homeodomain PF00046.29 ORX88882.1 - 3.8e-15 55.5 4.6 4.9e-15 55.1 4.6 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX88882.1 - 3.2e-05 23.7 0.1 6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 ORX88882.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain 2Fe-2S_thioredx PF01257.19 ORX88882.1 - 0.04 13.8 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Terminase_5 PF06056.12 ORX88882.1 - 0.046 13.6 0.1 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Ribosomal_L30 PF00327.20 ORX88883.1 - 7.1e-13 48.2 0.4 1.3e-12 47.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L37e PF01907.19 ORX88884.1 - 9.9e-28 96.1 13.0 1.7e-27 95.3 13.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX88884.1 - 0.0058 16.6 1.6 0.009 16.0 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORX88884.1 - 0.032 14.2 0.9 0.046 13.8 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORX88884.1 - 0.21 11.0 3.6 2.2 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORX88884.1 - 0.65 9.9 5.4 1.1 9.2 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CPSase_L_D2 PF02786.17 ORX88885.1 - 5.4e-82 274.4 0.2 9.7e-82 273.6 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORX88885.1 - 6.6e-46 155.4 0.0 1.6e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORX88885.1 - 1.6e-33 115.0 0.0 4.2e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 ORX88885.1 - 6.3e-30 104.1 0.0 1.9e-29 102.6 0.0 1.9 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 ORX88885.1 - 8.5e-14 51.1 1.1 8.5e-14 51.1 1.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORX88885.1 - 5e-09 36.0 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORX88885.1 - 7.1e-08 32.2 0.2 1.9e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 ORX88885.1 - 0.00015 21.4 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ORX88885.1 - 0.0026 17.8 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ORX88885.1 - 0.0051 17.5 1.3 0.92 10.2 0.1 3.6 3 0 0 3 3 3 1 HlyD family secretion protein ATP-grasp_5 PF13549.6 ORX88885.1 - 0.021 14.3 0.1 0.15 11.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORX88885.1 - 0.089 12.6 0.3 0.57 10.1 0.1 2.4 2 1 1 3 3 3 0 Biotin-lipoyl like LpxI_N PF17930.1 ORX88885.1 - 0.14 12.0 0.4 15 5.5 0.0 3.2 3 0 0 3 3 3 0 LpxI N-terminal domain RnfC_N PF13375.6 ORX88885.1 - 0.5 10.4 2.6 0.65 10.0 0.2 2.4 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain WD40 PF00400.32 ORX88888.1 - 1.1e-07 32.4 13.2 0.00085 20.1 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX88888.1 - 0.019 15.3 0.1 0.46 10.8 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Orthopox_A47 PF06334.11 ORX88888.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A47 protein AAA PF00004.29 ORX88889.1 - 2.7e-41 141.1 0.0 6.5e-41 139.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORX88889.1 - 1.2e-18 66.8 0.0 2.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORX88889.1 - 8.5e-10 38.3 0.3 8.5e-10 38.3 0.3 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 ORX88889.1 - 1.4e-05 25.1 3.0 0.00017 21.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX88889.1 - 6e-05 23.5 0.2 0.0081 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORX88889.1 - 0.00016 21.4 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX88889.1 - 0.00063 20.0 0.5 0.083 13.2 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ORX88889.1 - 0.00063 19.9 0.0 0.0051 16.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 ORX88889.1 - 0.0012 18.3 0.1 0.023 14.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 ORX88889.1 - 0.0022 17.2 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ORX88889.1 - 0.0042 16.5 0.1 0.014 14.7 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORX88889.1 - 0.0046 17.1 0.0 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORX88889.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 ORX88889.1 - 0.023 15.2 0.1 0.19 12.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORX88889.1 - 0.025 14.4 0.8 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 ORX88889.1 - 0.035 14.1 2.7 0.078 13.0 2.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATPase PF06745.13 ORX88889.1 - 0.036 13.4 1.2 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 ORX88889.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 ORX88889.1 - 0.051 12.8 0.3 0.43 9.7 0.0 2.1 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 ORX88889.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORX88889.1 - 0.062 13.0 0.9 0.25 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX88889.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ORX88889.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_13 PF13166.6 ORX88889.1 - 0.3 9.7 2.3 19 3.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORX88889.1 - 0.54 9.8 2.6 1.5 8.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain polyprenyl_synt PF00348.17 ORX88890.1 - 1e-38 132.9 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Skp1_POZ PF03931.15 ORX88891.1 - 3.4e-23 81.6 2.1 3.5e-23 81.5 0.1 2.0 2 1 1 3 3 3 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 ORX88891.1 - 2.8e-22 78.6 0.2 5.1e-22 77.7 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 ORX88891.1 - 0.00023 21.4 0.0 0.0026 18.0 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain Sororin PF09666.10 ORX88891.1 - 0.0061 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Sororin protein DUF615 PF04751.14 ORX88891.1 - 0.04 13.9 0.0 0.055 13.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF615) BshC PF10079.9 ORX88891.1 - 0.059 12.1 0.1 0.074 11.8 0.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC zf-MIZ PF02891.20 ORX88892.1 - 4.4e-20 71.2 3.0 1.5e-19 69.4 3.0 2.0 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Zmiz1_N PF18028.1 ORX88892.1 - 2.1e-12 47.2 0.2 4.3e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain zf-Nse PF11789.8 ORX88892.1 - 3.2e-05 23.6 1.8 7.6e-05 22.5 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Per1 PF04080.13 ORX88893.1 - 1.5e-99 332.9 12.5 1.8e-99 332.6 12.5 1.1 1 0 0 1 1 1 1 Per1-like family PARG_cat PF05028.14 ORX88894.1 - 2.3e-08 33.7 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) PDEase_I PF00233.19 ORX88895.1 - 1.7e-65 221.0 0.0 3.4e-65 220.1 0.0 1.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF5636 PF18686.1 ORX88895.1 - 0.073 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5636) SPRY PF00622.28 ORX88897.1 - 3.6e-18 65.8 0.2 5.5e-18 65.2 0.2 1.3 1 0 0 1 1 1 1 SPRY domain Dicty_CAR PF05462.11 ORX88898.1 - 3.4e-16 59.2 19.5 4.7e-16 58.8 19.5 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 ORX88898.1 - 7.1e-07 28.8 17.0 9.4e-07 28.4 17.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORX88898.1 - 4.7e-06 26.1 10.3 7.9e-06 25.4 10.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEMspv1-c74-12 PF11044.8 ORX88898.1 - 0.035 14.1 0.7 0.035 14.1 0.7 2.5 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Git3 PF11710.8 ORX88898.1 - 0.13 12.1 18.3 0.054 13.3 15.2 2.0 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 FPN1 PF06963.12 ORX88899.1 - 3.3e-105 352.2 24.9 4.2e-105 351.8 24.9 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) GrpE PF01025.19 ORX88900.1 - 3.2e-49 166.8 4.9 4e-49 166.5 4.9 1.0 1 0 0 1 1 1 1 GrpE Sigma70_ner PF04546.13 ORX88900.1 - 0.0038 17.1 4.1 0.0045 16.9 4.1 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region TerB_C PF15615.6 ORX88900.1 - 0.034 14.4 6.6 0.093 13.0 5.8 1.9 1 1 0 2 2 2 0 TerB-C domain Phospholamban PF04272.14 ORX88900.1 - 0.084 12.4 0.2 11 5.6 0.1 2.7 2 0 0 2 2 2 0 Phospholamban NPH3 PF03000.14 ORX88900.1 - 0.14 11.8 2.1 0.45 10.1 2.1 1.7 1 1 0 1 1 1 0 NPH3 family Citrate_ly_lig PF08218.11 ORX88901.1 - 0.053 13.2 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain V-ATPase_G PF03179.15 ORX88902.1 - 7.4e-30 103.6 16.9 8.4e-30 103.4 16.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 ORX88902.1 - 0.0043 17.1 13.0 0.0043 17.1 13.0 1.9 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) Pox_A3L PF05288.11 ORX88902.1 - 0.12 12.4 0.6 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A3L Protein V-ATPase_G_2 PF16999.5 ORX88902.1 - 0.18 12.2 16.5 12 6.3 12.4 2.7 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Cytochrom_B562 PF07361.11 ORX88902.1 - 0.55 10.9 9.3 6.1 7.6 9.3 2.0 1 1 0 1 1 1 0 Cytochrome b562 LPP20 PF02169.16 ORX88902.1 - 0.75 10.2 5.8 1.3 9.5 5.2 1.7 1 1 1 2 2 2 0 LPP20 lipoprotein PEP-utilisers_N PF05524.13 ORX88902.1 - 0.76 10.0 8.5 1 9.5 8.6 1.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Arrestin_C PF02752.22 ORX88903.1 - 4.4e-07 30.4 1.0 7.6e-06 26.4 0.2 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 ORX88903.1 - 0.034 13.1 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 AMP-binding PF00501.28 ORX88904.1 - 1.2e-103 346.9 0.0 1.6e-103 346.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme COR PF16095.5 ORX88904.1 - 0.051 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain AMP-binding_C PF13193.6 ORX88904.1 - 0.1 13.6 0.0 0.46 11.5 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Tyr-DNA_phospho PF06087.12 ORX88905.1 - 2.9e-46 158.2 0.0 3.3e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 ORX88905.1 - 0.00043 20.2 0.1 0.96 9.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Zn-ribbon_8 PF09723.10 ORX88906.1 - 0.044 13.9 0.2 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain SBP_bac_8 PF13416.6 ORX88910.1 - 1.5e-08 34.9 6.3 2.1e-08 34.3 6.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ORX88910.1 - 1.7e-06 27.9 0.0 2.8e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ORX88910.1 - 0.00022 20.7 2.0 0.00069 19.1 2.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ORX88910.1 - 0.001 19.1 8.9 0.017 15.1 8.9 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4636 PF15468.6 ORX88911.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) SGL PF08450.12 ORX88912.1 - 1.7e-27 96.6 0.2 2.6e-27 96.0 0.2 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ORX88912.1 - 6.3e-05 23.0 0.0 0.0066 16.5 0.0 2.9 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 ORX88912.1 - 0.00097 19.3 0.0 0.0063 16.7 0.0 2.5 2 0 0 2 2 2 1 Arylesterase ERO1 PF04137.15 ORX88913.1 - 7.9e-133 443.0 1.5 9.1e-133 442.8 1.5 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Calcipressin PF04847.12 ORX88914.1 - 6.5e-29 101.0 0.1 8.2e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 ORX88914.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.30 ORX88915.1 - 4.8e-23 81.4 0.0 9.8e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 ORX88915.1 - 1.7e-07 31.9 0.5 0.22 12.2 0.1 4.4 4 0 0 4 4 4 3 Putative heavy-metal-binding ArfGap PF01412.18 ORX88916.1 - 2.9e-39 133.8 0.1 8.3e-39 132.3 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 ORX88916.1 - 0.00072 19.4 0.1 0.0016 18.3 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Ribonuc_2-5A PF06479.12 ORX88917.1 - 1.8e-46 157.4 0.7 4.8e-46 156.1 0.7 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 ORX88917.1 - 6e-39 134.0 0.0 1.6e-29 103.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88917.1 - 5.9e-21 74.9 0.0 3.7e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 ORX88917.1 - 9.3e-06 25.4 0.0 0.00019 21.1 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain Pkinase_fungal PF17667.1 ORX88917.1 - 0.00018 20.5 0.0 0.00045 19.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 ORX88917.1 - 0.0067 16.3 0.2 44 4.3 0.1 4.5 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 ORX88917.1 - 0.014 15.8 0.0 3.5 8.2 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Kdo PF06293.14 ORX88917.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIT PF04212.18 ORX88921.1 - 1.4e-09 37.8 0.8 6.2e-09 35.8 1.0 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AKAP7_NLS PF10469.9 ORX88922.1 - 2.9e-14 53.5 0.0 1.6e-13 51.1 0.0 1.8 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 ORX88922.1 - 0.03 14.2 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily FH2 PF02181.23 ORX88923.1 - 4.8e-78 262.9 11.2 8.7e-78 262.0 11.2 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORX88923.1 - 8.2e-28 97.2 4.8 9.9e-14 51.3 0.0 3.0 2 1 1 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORX88923.1 - 1e-09 38.3 0.1 1e-09 38.3 0.1 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_DAD PF06345.11 ORX88923.1 - 0.0006 19.7 0.3 0.0021 18.0 0.3 2.0 1 0 0 1 1 1 1 DRF Autoregulatory Domain DUF4407 PF14362.6 ORX88923.1 - 0.038 13.4 1.5 0.068 12.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ORC_WH_C PF18137.1 ORX88923.1 - 0.14 12.2 2.6 1.2 9.3 2.1 2.6 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal C2 PF00168.30 ORX88924.1 - 1.2e-14 54.5 0.0 2.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 ORX88924.1 - 2.3e-11 44.1 4.4 0.00014 22.0 0.4 4.5 4 1 1 5 5 5 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 ORX88924.1 - 7.1e-07 28.2 0.3 7.1e-07 28.2 0.3 1.6 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) DUF2524 PF10732.9 ORX88924.1 - 0.074 13.4 1.3 0.22 11.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Erf4 PF10256.9 ORX88925.1 - 5e-31 107.2 0.0 9.9e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CytochromB561_N PF09786.9 ORX88925.1 - 2 7.3 12.8 2.2 7.1 12.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal FIBP PF05427.11 ORX88926.1 - 6.9e-89 298.6 2.7 7.7e-89 298.5 2.7 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) RRM_1 PF00076.22 ORX88929.1 - 3.1e-34 116.6 0.0 1e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX88929.1 - 9.1e-12 44.9 0.0 0.00017 21.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 ORX88929.1 - 0.0015 18.5 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PNRC PF15365.6 ORX88930.1 - 2e-07 30.6 3.8 2e-07 30.6 3.8 2.2 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif BAR PF03114.18 ORX88931.1 - 3.7e-42 144.6 10.1 4.9e-42 144.2 10.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 ORX88931.1 - 9.8e-13 47.7 0.2 1.8e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX88931.1 - 1.2e-12 47.2 0.1 2.3e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX88931.1 - 2e-11 43.4 0.2 3.4e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 ORX88931.1 - 0.00069 19.4 8.0 0.0011 18.8 7.8 1.4 1 1 0 1 1 1 1 BAR domain of APPL family DUF3104 PF11302.8 ORX88931.1 - 0.2 11.4 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) ADH_N PF08240.12 ORX88934.1 - 9.7e-23 80.1 3.2 9.7e-23 80.1 3.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX88934.1 - 1.6e-18 66.9 0.0 2.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORX88934.1 - 7.1e-06 25.5 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORX88934.1 - 8.1e-05 22.0 0.1 0.00012 21.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORX88934.1 - 0.0033 18.5 0.0 0.0053 17.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GFO_IDH_MocA PF01408.22 ORX88934.1 - 0.018 15.8 0.0 0.031 15.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ELFV_dehydrog PF00208.21 ORX88934.1 - 0.07 12.8 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RRM_1 PF00076.22 ORX88935.1 - 2.5e-09 36.8 0.1 7.5e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX88935.1 - 0.013 15.1 0.0 0.32 10.6 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_D_N PF18018.1 ORX88935.1 - 0.029 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain G-alpha PF00503.20 ORX88937.1 - 1.9e-114 382.5 0.3 2.2e-114 382.3 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX88937.1 - 6.5e-15 55.0 0.5 1.5e-09 37.6 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX88937.1 - 6.2e-05 22.5 0.1 0.32 10.3 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX88937.1 - 0.0015 18.8 0.1 0.56 10.4 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORX88937.1 - 0.033 14.3 0.2 8.9 6.4 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX88937.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMP_C2CD2L PF18696.1 ORX88937.1 - 0.16 11.8 0.3 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain Pkinase PF00069.25 ORX88938.1 - 3.8e-67 226.4 0.0 5e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88938.1 - 9.7e-36 123.4 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX88938.1 - 7.6e-08 32.0 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX88938.1 - 0.00023 20.6 0.3 0.00036 20.0 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX88938.1 - 0.0018 18.0 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORX88938.1 - 0.0026 16.6 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX88938.1 - 0.08 12.9 1.3 0.24 11.3 1.8 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORX88938.1 - 0.19 10.7 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PhoLip_ATPase_C PF16212.5 ORX88939.1 - 1.1e-63 215.3 23.8 1.1e-63 215.3 23.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX88939.1 - 3.3e-22 78.0 6.8 3.3e-22 78.0 6.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORX88939.1 - 1.8e-11 44.0 0.0 6.1e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX88939.1 - 2.7e-10 40.9 1.0 0.00022 21.6 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX88939.1 - 7.1e-10 38.7 0.0 7.1e-10 38.7 0.0 3.2 2 1 1 3 3 3 1 E1-E2 ATPase Arm PF00514.23 ORX88940.1 - 6.6e-13 48.2 7.2 0.01 15.9 0.1 6.4 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 ORX88940.1 - 9.1e-09 35.2 2.2 9.6e-05 22.3 0.2 3.3 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 ORX88940.1 - 0.013 15.0 7.2 0.81 9.1 0.2 4.1 3 2 1 5 5 5 0 Armadillo-like HEAT PF02985.22 ORX88940.1 - 0.039 14.2 1.9 2.3 8.7 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat DUF3818 PF12825.7 ORX88941.1 - 5e-86 288.8 3.4 7.8e-86 288.2 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORX88941.1 - 1.4e-14 54.1 0.8 8.8e-14 51.6 0.3 2.4 2 0 0 2 2 2 1 PX-associated PX PF00787.24 ORX88941.1 - 0.00074 19.5 0.5 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 PX domain Sin3_corepress PF08295.12 ORX88941.1 - 0.059 13.4 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 Sin3 family co-repressor TAF4 PF05236.14 ORX88941.1 - 0.84 9.3 4.0 0.75 9.5 1.7 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family EAV_GP5 PF15981.5 ORX88943.1 - 6.4 7.3 9.5 0.88 10.0 1.0 3.1 2 1 1 3 3 3 0 Envelope glycoprotein GP 5 of equine arteritis virus SNF2_N PF00176.23 ORX88944.1 - 9.4e-68 228.5 0.1 2.9e-67 226.9 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX88944.1 - 1.7e-20 73.4 4.1 3.2e-20 72.5 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORX88944.1 - 6e-15 55.2 1.5 1.6e-14 53.7 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORX88944.1 - 6.5e-10 39.3 0.1 6.2e-09 36.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORX88944.1 - 9.4e-06 25.5 0.0 9.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C2H2 PF00096.26 ORX88945.1 - 1.3e-12 47.4 14.3 1.2e-07 31.8 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX88945.1 - 8.2e-10 38.7 11.2 3.2e-06 27.5 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX88945.1 - 1.1e-07 31.9 3.1 1.1e-07 31.9 3.1 3.2 3 1 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 ORX88945.1 - 3.8e-05 24.2 1.8 0.0074 16.9 0.3 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORX88945.1 - 7e-05 23.1 2.0 0.16 12.4 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX88945.1 - 8.4e-05 22.5 7.7 0.00012 21.9 1.4 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORX88945.1 - 0.00014 22.1 1.9 0.00025 21.2 1.9 1.5 1 1 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORX88945.1 - 0.0049 17.1 9.2 0.098 13.0 0.4 3.0 2 2 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 ORX88945.1 - 0.0096 15.9 0.9 0.18 11.8 0.1 2.1 1 1 1 2 2 2 1 Ogr/Delta-like zinc finger zf-C2HE PF16278.5 ORX88945.1 - 0.014 15.8 10.1 0.68 10.4 1.4 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 ORX88945.1 - 0.018 15.3 3.1 0.51 10.7 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 ORX88945.1 - 0.023 15.4 4.8 0.045 14.4 4.8 1.6 1 1 0 1 1 1 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 ORX88945.1 - 0.026 14.3 14.9 0.03 14.1 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 ORX88945.1 - 0.03 14.6 3.7 0.14 12.5 3.0 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-LYAR PF08790.11 ORX88945.1 - 0.033 14.1 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger IBR PF01485.21 ORX88945.1 - 0.05 13.8 2.5 1.1 9.5 0.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-BED PF02892.15 ORX88945.1 - 0.086 12.9 6.7 0.11 12.5 0.1 2.4 2 1 0 2 2 2 0 BED zinc finger Pkinase PF00069.25 ORX88946.1 - 2.9e-72 243.2 0.0 4.6e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88946.1 - 2.1e-35 122.3 0.0 5e-35 121.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Vip3A_N PF12495.8 ORX88946.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal DUF1387 PF07139.11 ORX88946.1 - 0.2 11.3 7.8 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) WW PF00397.26 ORX88947.1 - 5e-11 42.5 2.0 1.2e-10 41.3 2.0 1.7 1 0 0 1 1 1 1 WW domain Gly-zipper_Omp PF13488.6 ORX88947.1 - 0.0063 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Glycine zipper zf-C2H2 PF00096.26 ORX88948.1 - 1.2e-09 38.1 13.5 2.4e-06 27.7 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX88948.1 - 4.7e-06 27.0 11.4 0.00047 20.8 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX88948.1 - 5e-05 23.5 1.7 5e-05 23.5 1.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX88948.1 - 0.00036 20.5 2.8 0.00042 20.2 0.4 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX88948.1 - 0.013 15.7 0.3 0.034 14.4 0.3 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORX88948.1 - 0.021 15.4 3.7 0.2 12.3 0.5 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORX88948.1 - 0.15 12.2 3.0 6.6 6.8 0.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 ORX88948.1 - 0.18 12.2 2.8 5.4 7.4 0.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX88948.1 - 0.21 11.4 8.0 0.53 10.1 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MFS_1 PF07690.16 ORX88949.1 - 1.8e-51 175.1 51.6 1.8e-51 175.1 51.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX88949.1 - 4.2e-20 71.7 27.7 6.3e-20 71.1 27.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX88949.1 - 4.4e-17 62.1 5.4 4.4e-17 62.1 5.4 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 ORX88950.1 - 5.1e-21 74.9 3.4 5.1e-21 74.9 3.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX88950.1 - 2.1e-08 34.2 17.9 2.1e-08 34.2 17.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 ORX88953.1 - 1.1e-59 202.1 0.1 1.8e-59 201.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TusA PF01206.17 ORX88953.1 - 3.9e-17 61.8 0.1 7.5e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA Pyr_redox_dim PF02852.22 ORX88953.1 - 1.8e-14 53.9 1.1 1.6e-12 47.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORX88953.1 - 1.9e-14 54.0 3.2 1.9e-14 54.0 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 ORX88953.1 - 3.6e-12 46.8 0.0 1.1e-11 45.2 0.0 1.8 2 0 0 2 2 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 ORX88953.1 - 7.2e-11 41.9 0.3 2.1e-09 37.1 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX88953.1 - 7.6e-07 29.3 2.7 0.038 14.2 0.2 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORX88953.1 - 0.00048 20.2 2.3 1.2 9.1 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORX88953.1 - 0.0012 18.0 3.0 0.087 11.9 0.4 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 ORX88953.1 - 0.006 15.9 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 ORX88953.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 ORX88953.1 - 0.027 14.0 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_binding_2 PF00890.24 ORX88953.1 - 0.03 13.4 5.7 1.2 8.2 0.3 3.2 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 ORX88953.1 - 0.039 13.8 0.9 0.07 13.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RELT PF12606.8 ORX88953.1 - 0.044 12.8 0.1 0.077 12.0 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 HI0933_like PF03486.14 ORX88953.1 - 0.06 12.0 6.1 1.8 7.2 1.0 3.1 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 ORX88953.1 - 0.098 11.9 0.8 0.25 10.5 0.6 1.7 1 1 0 1 1 1 0 FAD binding domain DAO PF01266.24 ORX88953.1 - 0.12 11.9 6.6 0.81 9.2 0.2 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Protoglobin PF11563.8 ORX88954.1 - 9.7e-11 41.8 0.0 1.3e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin ABC_tran PF00005.27 ORX88957.1 - 5.1e-11 43.2 0.0 6.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.9 ORX88957.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 ORX88957.1 - 0.027 14.7 0.2 0.96 9.7 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Phage_T4_Ndd PF06591.11 ORX88957.1 - 0.046 13.5 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Pet127 PF08634.10 ORX88960.1 - 3e-104 348.3 0.1 3.6e-104 348.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Hydrolase_6 PF13344.6 ORX88961.1 - 4.2e-28 97.4 0.0 1e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX88961.1 - 2.4e-17 62.7 0.0 4.9e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORX88961.1 - 6.9e-07 29.8 0.0 1.4e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX88961.1 - 5.7e-06 26.5 0.0 0.0034 17.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Alb1 PF09135.11 ORX88962.1 - 0.019 15.8 14.1 0.022 15.6 14.1 1.1 1 0 0 1 1 1 0 Alb1 DUF2018 PF09442.10 ORX88962.1 - 0.047 14.6 0.5 7.7 7.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF4570 PF15134.6 ORX88962.1 - 0.076 13.0 4.8 0.093 12.8 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) FerI PF08151.12 ORX88963.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 FerI (NUC094) domain Lzipper-MIP1 PF14389.6 ORX88963.1 - 0.15 12.4 8.3 2.9 8.3 1.1 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Methyltransf_16 PF10294.9 ORX88964.1 - 6e-29 101.0 0.0 7.2e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORX88964.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SrfB PF07520.11 ORX88964.1 - 0.13 10.2 0.1 0.16 9.8 0.1 1.1 1 0 0 1 1 1 0 Virulence factor SrfB MTS PF05175.14 ORX88964.1 - 0.14 11.7 0.1 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Atg14 PF10186.9 ORX88965.1 - 8.4e-13 48.1 0.1 9.7e-13 47.9 0.1 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 ORX88966.1 - 0.0014 18.9 7.4 0.39 11.0 0.2 4.7 4 1 0 4 4 4 2 Uncharacterized conserved protein IIGP PF05049.13 ORX88966.1 - 0.035 13.1 0.2 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) THDPS_N_2 PF14805.6 ORX88966.1 - 0.096 12.9 0.2 0.37 11.1 0.2 2.1 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Baculo_PEP_C PF04513.12 ORX88966.1 - 0.27 11.3 0.0 0.27 11.3 0.0 4.0 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4168 PF13767.6 ORX88966.1 - 3.8 8.8 8.2 26 6.1 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4168) DUF1664 PF07889.12 ORX88966.1 - 4.8 7.2 11.7 7.8 6.6 0.0 5.0 5 2 0 5 5 5 0 Protein of unknown function (DUF1664) Dus PF01207.17 ORX88967.1 - 3.3e-55 187.4 0.1 7.5e-55 186.2 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Skp1 PF01466.19 ORX88967.1 - 0.042 14.0 0.4 0.11 12.6 0.4 1.7 1 0 0 1 1 1 0 Skp1 family, dimerisation domain His_biosynth PF00977.21 ORX88967.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein F-box-like PF12937.7 ORX88968.1 - 2.3e-07 30.6 2.2 2.3e-07 30.6 2.2 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 ORX88968.1 - 3.4e-05 23.5 1.0 1.7 8.9 0.1 5.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 ORX88968.1 - 0.00046 20.5 0.3 0.013 15.9 0.1 7.0 6 1 2 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX88968.1 - 0.11 12.3 7.5 0.3 10.9 0.0 4.6 4 1 1 5 5 5 0 Leucine rich repeat FTH PF01827.27 ORX88968.1 - 0.13 12.0 3.7 0.11 12.3 1.1 2.3 2 1 0 2 2 2 0 FTH domain zf-HC5HC2H_2 PF13832.6 ORX88969.1 - 6.3e-21 74.6 27.8 6.9e-21 74.5 9.9 4.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORX88969.1 - 9.3e-19 67.5 24.6 1.3e-18 67.0 3.9 4.7 3 1 0 3 3 3 2 PHD-like zinc-binding domain BAH PF01426.18 ORX88969.1 - 5.8e-16 58.5 1.1 1.4e-15 57.2 1.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 ORX88969.1 - 4.4e-10 39.3 22.8 1.6e-06 27.9 5.0 5.1 5 1 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 ORX88969.1 - 1e-09 37.8 3.5 1e-09 37.8 3.5 5.8 6 1 1 7 7 7 1 PHD-finger GATA PF00320.27 ORX88969.1 - 2.8e-05 23.6 0.3 2.8e-05 23.6 0.3 4.5 4 1 0 4 4 4 1 GATA zinc finger C1_2 PF03107.16 ORX88969.1 - 0.0021 18.3 0.6 0.0021 18.3 0.6 6.3 6 0 0 6 6 6 2 C1 domain ELM2 PF01448.24 ORX88969.1 - 0.0039 17.9 0.1 0.018 15.7 0.0 2.4 2 1 0 2 2 2 1 ELM2 domain C1_1 PF00130.22 ORX88969.1 - 0.008 16.0 0.8 0.008 16.0 0.8 6.5 6 2 2 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-bind_7 PF15963.5 ORX88969.1 - 0.039 13.9 2.8 0.13 12.1 2.8 1.9 1 0 0 1 1 1 0 Myb DNA-binding like Methyltransf_16 PF10294.9 ORX88971.1 - 4e-32 111.3 0.5 8.4e-32 110.3 0.5 1.5 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORX88971.1 - 0.046 13.1 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORX88971.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 ORX88971.1 - 0.094 12.5 0.7 0.31 10.8 0.7 1.9 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORX88971.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF525 PF04379.14 ORX88972.1 - 4.3e-18 65.3 0.0 6.8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 ApaG domain F-box-like PF12937.7 ORX88972.1 - 1.6e-09 37.5 0.3 2.4e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 ORX88972.1 - 8.7e-06 25.5 0.0 7.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain Leucyl-specific PF14795.6 ORX88973.1 - 0.21 11.7 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain DUF3472 PF11958.8 ORX88975.1 - 2.3e-11 44.5 0.7 3.6e-11 43.8 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX88975.1 - 8.5e-08 32.6 13.7 1.9e-07 31.4 13.7 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORX88975.1 - 0.014 15.3 0.2 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) Acetyltransf_8 PF13523.6 ORX88975.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4937 PF16291.5 ORX88975.1 - 0.054 13.8 0.5 0.097 12.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 DUF3472 PF11958.8 ORX88976.1 - 1.9e-11 44.8 0.7 3e-11 44.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX88976.1 - 8.4e-08 32.6 13.7 1.9e-07 31.4 13.7 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORX88976.1 - 0.014 15.3 0.2 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) Acetyltransf_8 PF13523.6 ORX88976.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4937 PF16291.5 ORX88976.1 - 0.054 13.7 0.5 0.097 12.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 Got1 PF04178.12 ORX88978.1 - 8.2e-18 64.9 13.0 9.4e-18 64.7 13.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family MTHFR PF02219.17 ORX88979.1 - 2.4e-121 404.5 0.0 3.1e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PPR_2 PF13041.6 ORX88980.1 - 4.6e-170 551.8 27.8 8.3e-17 61.1 0.0 21.0 6 4 15 21 21 21 19 PPR repeat family PPR_1 PF12854.7 ORX88980.1 - 7.4e-113 367.9 6.4 1.3e-09 37.6 0.0 21.1 23 0 0 23 23 22 16 PPR repeat PPR PF01535.20 ORX88980.1 - 2.8e-112 359.5 29.9 9.5e-07 28.7 0.1 21.3 22 0 0 22 22 21 18 PPR repeat PPR_3 PF13812.6 ORX88980.1 - 1.3e-95 313.4 17.9 8.8e-11 41.7 0.0 14.3 8 3 5 15 15 15 14 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX88980.1 - 2e-64 216.9 2.3 2.1e-10 40.3 0.0 8.4 3 1 6 9 9 9 9 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX88980.1 - 3.9e-17 61.5 0.5 21 6.2 0.0 13.2 9 5 6 15 15 14 0 Tetratricopeptide repeat RPM2 PF08579.11 ORX88980.1 - 1.3e-15 57.8 15.7 0.3 11.5 0.1 12.2 5 3 6 12 12 12 4 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX88980.1 - 1e-10 41.1 4.7 0.021 13.7 0.0 6.3 4 3 2 6 6 6 3 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 ORX88980.1 - 2.1e-10 40.5 4.4 0.41 10.5 0.0 8.6 4 2 7 12 12 12 2 Mitochondrial ATPase expression TPR_7 PF13176.6 ORX88980.1 - 4.8e-07 29.4 1.6 37 4.7 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 ORX88980.1 - 3.1e-05 23.7 0.0 8.3 6.0 0.0 5.3 4 1 1 5 5 5 1 Rab-GTPase-TBC domain ECSIT PF06239.11 ORX88980.1 - 0.00059 19.0 7.4 18 4.3 0.0 7.3 7 1 0 7 7 7 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_2 PF07719.17 ORX88980.1 - 0.0024 17.9 3.3 1.4e+02 2.9 0.1 6.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyoxalase_2 PF12681.7 ORX88980.1 - 0.0037 17.2 0.5 5.6 6.9 0.0 5.0 4 2 2 6 6 6 1 Glyoxalase-like domain Exog_C PF18026.1 ORX88980.1 - 0.0058 16.7 0.2 18 5.5 0.0 5.0 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain Inhibitor_I9 PF05922.16 ORX88980.1 - 0.0084 16.8 1.0 1.4 9.7 0.0 4.8 3 3 3 6 6 5 1 Peptidase inhibitor I9 Clathrin PF00637.20 ORX88980.1 - 0.03 14.2 8.7 9.9 6.0 0.0 6.2 6 2 2 8 8 8 0 Region in Clathrin and VPS DUF4248 PF14053.6 ORX88980.1 - 0.14 12.2 0.1 33 4.6 0.0 4.6 5 0 0 5 5 4 0 Domain of unknown function (DUF4248) Glyco_trans_4_3 PF12000.8 ORX88980.1 - 0.15 11.7 0.0 21 4.8 0.0 4.0 3 1 2 5 5 5 0 Glycosyl transferase family 4 group GMP_synt_C PF00958.22 ORX88980.1 - 0.21 11.7 1.7 6.4 6.9 0.0 3.9 5 0 0 5 5 3 0 GMP synthase C terminal domain Prp18 PF02840.15 ORX88980.1 - 0.85 9.7 6.8 19 5.3 0.0 5.5 6 2 1 8 8 8 0 Prp18 domain Ribonuclease_T2 PF00445.18 ORX88982.1 - 3.5e-38 131.7 0.6 4.4e-38 131.3 0.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Glucokinase PF02685.16 ORX88982.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Glucokinase CAP PF00188.26 ORX88983.1 - 1.5e-16 61.4 0.0 2.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHAP PF05257.16 ORX88985.1 - 2.8e-11 43.8 3.7 4.5e-11 43.2 3.7 1.3 1 0 0 1 1 1 1 CHAP domain DUF4994 PF16385.5 ORX88985.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function CHAP PF05257.16 ORX88986.1 - 2.8e-11 43.8 3.7 4.5e-11 43.2 3.7 1.3 1 0 0 1 1 1 1 CHAP domain DUF4994 PF16385.5 ORX88986.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Y_phosphatase2 PF03162.13 ORX88987.1 - 5.1e-43 146.5 0.0 6.3e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Pan3_PK PF18101.1 ORX88988.1 - 1.4e-66 222.7 0.1 2.2e-66 222.0 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 ORX88988.1 - 2.7e-06 26.9 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX88988.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase T3RM_EcoP15I_C PF18273.1 ORX88988.1 - 0.06 13.7 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain 7tm_7 PF08395.12 ORX88989.1 - 0.012 14.8 5.6 0.016 14.4 4.4 1.9 1 1 0 1 1 1 0 7tm Chemosensory receptor Flu_M2 PF00599.17 ORX88989.1 - 0.092 12.9 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Influenza Matrix protein (M2) DUF4381 PF14316.6 ORX88989.1 - 0.19 12.0 0.6 0.3 11.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) 7TMR-DISM_7TM PF07695.11 ORX88989.1 - 2.8 7.8 11.3 0.16 11.8 5.2 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling Glycoprotein_B PF00606.18 ORX88990.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain GPI-anchored PF10342.9 ORX88990.1 - 0.1 13.4 0.0 0.45 11.3 0.0 1.9 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HLH PF00010.26 ORX88991.1 - 1.1e-15 57.4 1.7 1.8e-15 56.6 1.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tex_N PF09371.10 ORX88991.1 - 0.036 13.7 0.7 0.047 13.4 0.4 1.4 1 1 0 1 1 1 0 Tex-like protein N-terminal domain HrpA_pilin PF09589.10 ORX88991.1 - 0.045 14.5 0.1 0.068 13.9 0.1 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein UPF0242 PF06785.11 ORX88991.1 - 0.087 12.9 3.2 0.097 12.8 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mito_carr PF00153.27 ORX88992.1 - 7e-76 250.3 0.3 1.3e-26 92.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 ORX88992.1 - 0.073 13.2 0.1 21 5.3 0.0 2.7 3 0 0 3 3 3 0 PrcB C-terminal Ribosomal_S13 PF00416.22 ORX88993.1 - 2.2e-56 189.8 2.5 2.5e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORX88993.1 - 0.0058 15.4 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 ORX88993.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP28 PF10252.9 ORX88993.1 - 0.12 12.8 0.4 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Ribosomal_S19e PF01090.19 ORX88994.1 - 2.7e-59 198.8 0.3 3e-59 198.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Alg6_Alg8 PF03155.15 ORX88995.1 - 6.5e-145 483.8 33.9 8.3e-145 483.5 33.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family HD PF01966.22 ORX88996.1 - 3.2e-14 53.2 0.3 1.3e-13 51.2 0.2 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 ORX88996.1 - 0.0012 18.7 0.5 0.0052 16.5 0.0 2.2 2 2 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S16 PF00886.19 ORX88997.1 - 1e-26 92.7 0.0 1.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Bac_globin PF01152.21 ORX88998.1 - 6.2e-08 32.8 0.2 8.7e-08 32.3 0.2 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX88998.1 - 0.0041 17.0 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Cyclin PF08613.11 ORX89002.1 - 2.1e-09 38.0 0.1 2.8e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX89002.1 - 9.1e-05 22.2 0.6 0.00014 21.6 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Gly_transf_sug PF04488.15 ORX89003.1 - 8.4e-09 36.0 0.1 5.7e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORX89003.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORX89003.1 - 0.028 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cyclin_N PF00134.23 ORX89004.1 - 4.9e-07 29.6 0.0 6.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX89004.1 - 8.1e-05 23.0 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin Chitin_synth_1 PF01644.17 ORX89005.1 - 7.1e-74 247.2 0.2 1.2e-73 246.4 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORX89005.1 - 2.8e-26 92.2 2.8 2.4e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORX89005.1 - 4.5e-26 90.6 0.0 9.8e-26 89.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORX89005.1 - 2e-08 34.4 4.4 2e-08 34.4 4.4 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX89005.1 - 0.00089 19.2 0.0 0.0086 16.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 TniB PF05621.11 ORX89005.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Cyclin_N PF00134.23 ORX89006.1 - 3.8e-05 23.4 0.2 0.0089 15.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin PF08613.11 ORX89006.1 - 0.031 14.7 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin Ribosomal_S7 PF00177.21 ORX89007.1 - 6.2e-37 126.5 0.8 7.7e-37 126.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1965 PF09248.10 ORX89008.1 - 0.12 12.2 0.3 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Prismane PF03063.20 ORX89009.1 - 3.3e-140 468.2 0.0 4.2e-140 467.8 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 ORX89009.1 - 3.6e-49 167.3 0.1 6e-49 166.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX89009.1 - 7.3e-28 97.6 0.0 1.5e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORX89009.1 - 3.9e-05 24.3 0.0 0.00028 21.5 0.0 2.3 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain VIT1 PF01988.19 ORX89009.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 VIT family Flavodoxin_5 PF12724.7 ORX89009.1 - 0.19 12.0 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain IDO PF01231.18 ORX89010.1 - 3.6e-145 484.1 0.0 4.1e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cyclin PF08613.11 ORX89011.1 - 6.8e-09 36.3 0.0 8.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX89011.1 - 5.5e-07 29.4 0.0 8.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain SWIM PF04434.17 ORX89013.1 - 0.00089 18.9 0.1 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 SWIM zinc finger ATP_sub_h PF10775.9 ORX89014.1 - 9.2e-17 60.8 1.5 3e-15 56.0 1.5 2.1 1 1 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 ORX89014.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Peptidase_C65 PF10275.9 ORX89015.1 - 8.6e-71 238.3 0.9 1e-70 238.0 0.9 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 ORX89015.1 - 1.7e-08 35.0 0.3 7.6e-07 29.7 0.3 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Skp1_POZ PF03931.15 ORX89015.1 - 0.086 13.0 0.7 0.48 10.6 0.0 2.4 3 0 0 3 3 3 0 Skp1 family, tetramerisation domain Peptidase_C101 PF16218.5 ORX89015.1 - 0.096 11.9 0.1 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C101 NRBF2_MIT PF17169.4 ORX89016.1 - 0.00018 21.6 3.2 0.00018 21.6 3.2 3.0 3 0 0 3 3 3 1 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 ORX89016.1 - 0.041 14.0 0.5 0.041 14.0 0.5 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain CtIP_N PF10482.9 ORX89016.1 - 0.27 11.3 8.7 3.5 7.7 1.1 3.4 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain BLOC1_2 PF10046.9 ORX89016.1 - 1.7 9.0 12.7 2.1 8.7 1.5 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TSC22 PF01166.18 ORX89016.1 - 2.1 8.7 8.5 10 6.5 1.4 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 ORX89016.1 - 4.2 7.5 17.1 1.4 9.1 5.6 3.4 3 1 1 4 4 4 0 bZIP transcription factor Histone PF00125.24 ORX89017.1 - 4.6e-43 146.7 0.2 5e-43 146.6 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORX89017.1 - 0.0029 17.7 0.2 0.0042 17.2 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORX89017.1 - 0.0045 17.3 0.1 0.0063 16.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX89017.1 - 0.0094 16.2 0.2 0.018 15.3 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aminotran_1_2 PF00155.21 ORX89018.1 - 1.3e-61 208.9 0.0 1.5e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORX89018.1 - 7.3e-07 28.8 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORX89018.1 - 7.8e-06 24.7 0.0 1.4e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORX89018.1 - 0.00096 18.2 0.0 0.0034 16.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 ORX89018.1 - 0.015 14.1 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 ORX89018.1 - 0.2 10.9 0.0 0.34 10.1 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Arrestin_N PF00339.29 ORX89019.1 - 8.8e-09 35.6 0.0 3.9e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX89019.1 - 2.4e-05 24.8 0.7 0.0011 19.4 0.2 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX89019.1 - 0.00016 21.4 0.0 0.00072 19.3 0.0 2.0 1 1 1 2 2 2 1 Arrestin_N terminal like Vps26 PF03643.15 ORX89019.1 - 0.0094 15.0 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 ORX89020.1 - 5.3e-05 23.7 0.0 0.00082 19.8 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX89020.1 - 0.0014 18.7 0.0 0.0034 17.4 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain C2 PF00168.30 ORX89022.1 - 2.1e-15 56.9 0.0 3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 ORX89022.1 - 0.0023 18.0 0.0 0.0031 17.6 0.0 1.3 1 1 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 Aminotran_1_2 PF00155.21 ORX89023.1 - 2.3e-40 138.9 0.0 2.8e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX89023.1 - 0.0025 16.4 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ORX89023.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PBP PF01161.20 ORX89024.1 - 2.8e-22 79.4 0.1 3.7e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Urb2 PF10441.9 ORX89025.1 - 3.5e-39 134.9 0.0 4.4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Urb2/Npa2 family Auts2 PF15336.6 ORX89025.1 - 0.084 13.0 0.1 0.19 11.8 0.2 1.5 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein LisH_2 PF16045.5 ORX89025.1 - 0.81 8.8 3.5 11 5.1 1.1 2.4 2 0 0 2 2 2 0 LisH EST1_DNA_bind PF10373.9 ORX89026.1 - 1.5e-46 159.2 3.1 2.3e-46 158.6 3.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 ORX89026.1 - 8.4e-21 75.0 1.5 8.4e-21 75.0 1.5 3.2 2 1 1 3 3 3 1 Telomerase activating protein Est1 TPR_1 PF00515.28 ORX89026.1 - 7.2e-05 22.4 0.8 0.00039 20.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89026.1 - 9.1e-05 22.1 0.7 0.00021 20.9 0.7 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 ORX89026.1 - 0.00013 21.8 1.7 0.00045 20.1 0.4 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat PSD4 PF07631.11 ORX89026.1 - 0.01 16.4 0.6 0.14 12.7 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1592) TPR_12 PF13424.6 ORX89026.1 - 0.013 15.8 0.4 0.043 14.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORX89026.1 - 0.023 15.0 0.1 0.069 13.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DXPR_C PF13288.6 ORX89026.1 - 0.053 13.8 0.4 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain TPR_14 PF13428.6 ORX89026.1 - 0.06 14.2 0.2 0.19 12.6 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5522 PF17653.1 ORX89027.1 - 5.3e-24 83.9 6.7 7.4e-24 83.5 6.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5522) N36 PF11438.8 ORX89027.1 - 0.24 11.3 2.5 0.38 10.6 2.4 1.4 1 1 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) RSN1_7TM PF02714.15 ORX89028.1 - 2.5e-81 273.0 25.6 4.7e-81 272.1 25.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX89028.1 - 7e-38 130.6 0.1 1.1e-37 130.0 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORX89028.1 - 7.8e-36 123.2 2.5 7.8e-36 123.2 2.5 3.5 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 ORX89028.1 - 2.1e-13 50.2 0.0 5.2e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Anoctamin PF04547.12 ORX89028.1 - 0.0022 16.9 11.4 0.029 13.2 11.4 2.4 1 1 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.28 ORX89031.1 - 1.7e-39 136.4 0.1 2.2e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX89031.1 - 7.3e-23 80.8 0.1 1.8e-22 79.5 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L29e PF01779.17 ORX89032.1 - 1.5e-24 86.0 11.5 2e-24 85.6 11.5 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family PWI PF01480.17 ORX89033.1 - 8.5e-29 99.7 0.6 8.5e-29 99.7 0.6 1.6 2 0 0 2 2 2 1 PWI domain Alba PF01918.21 ORX89034.1 - 0.18 11.6 0.4 8.1 6.4 0.1 2.4 2 0 0 2 2 2 0 Alba Methyltransf_23 PF13489.6 ORX89036.1 - 5.4e-15 55.6 0.0 7.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX89036.1 - 7.1e-10 39.4 0.0 2.1e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX89036.1 - 1.7e-08 35.0 0.1 1.6e-07 31.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89036.1 - 1.8e-08 35.1 0.0 6.4e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX89036.1 - 1.6e-07 31.3 0.0 7.7e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain CheR PF01739.18 ORX89036.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 ORX89036.1 - 0.026 13.9 0.2 0.16 11.4 0.0 2.4 1 1 1 2 2 2 0 Tellurite resistance protein TehB Methyltransf_20 PF12147.8 ORX89036.1 - 0.045 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.17 ORX89036.1 - 0.095 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 ORX89036.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Band_7 PF01145.25 ORX89037.1 - 6.2e-27 94.8 0.6 8.8e-27 94.2 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX89037.1 - 0.046 13.4 0.1 0.093 12.4 0.1 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORX89037.1 - 0.058 13.0 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Thaumatin PF00314.17 ORX89038.1 - 3.2e-68 229.5 12.9 3.7e-68 229.4 12.9 1.0 1 0 0 1 1 1 1 Thaumatin family Ribosomal_L7Ae PF01248.26 ORX89039.1 - 3.3e-23 81.2 0.7 3.3e-23 81.2 0.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GalP_UDP_tr_C PF02744.17 ORX89039.1 - 0.018 14.8 0.2 0.5 10.1 0.0 2.4 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain ATPase_2 PF01637.18 ORX89039.1 - 0.037 13.9 0.4 0.072 13.0 0.4 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HECT PF00632.25 ORX89040.1 - 2.5e-96 322.8 0.0 3.4e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 ORX89041.1 - 0.0058 16.3 1.1 0.028 14.2 0.3 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF3605 PF12239.8 ORX89042.1 - 5.1e-28 98.3 0.1 2.1e-25 89.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) EF-hand_1 PF00036.32 ORX89043.1 - 2.3e-40 133.1 14.3 5.6e-10 38.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX89043.1 - 4.1e-36 123.3 4.8 7.7e-19 67.9 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX89043.1 - 2.2e-32 110.7 13.3 5.9e-16 58.1 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ORX89043.1 - 5.4e-31 103.8 9.2 3.2e-09 36.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORX89043.1 - 7.5e-25 85.3 13.2 1.1e-06 27.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORX89043.1 - 2.9e-15 56.3 0.2 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORX89043.1 - 1.8e-09 37.4 2.4 5.8e-05 23.0 0.3 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORX89043.1 - 1.7e-08 34.8 0.6 0.0037 17.6 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 ORX89043.1 - 1.8e-06 28.8 0.0 0.00053 20.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 ORX89043.1 - 1.6e-05 24.9 0.0 0.04 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 ORX89043.1 - 3.5e-05 23.9 3.8 0.087 13.0 0.5 3.1 1 1 3 4 4 4 2 Dockerin type I domain DUF3349 PF11829.8 ORX89043.1 - 7.4e-05 23.5 0.3 0.46 11.3 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) EFhand_Ca_insen PF08726.10 ORX89043.1 - 0.00024 21.1 0.5 0.0024 18.0 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 ORX89043.1 - 0.0021 18.0 1.2 0.7 9.8 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein DUF4497 PF14924.6 ORX89043.1 - 0.0022 18.4 0.0 0.41 11.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 ORX89043.1 - 0.0024 18.2 0.4 1.6 9.1 0.1 2.8 2 1 1 3 3 3 1 RNA polymerase Rpb4 TerB PF05099.13 ORX89043.1 - 0.0064 16.5 0.4 0.36 10.8 0.1 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB SurA_N_2 PF13623.6 ORX89043.1 - 0.012 15.5 1.1 1.1 9.1 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain SurA_N_3 PF13624.6 ORX89043.1 - 0.013 15.3 1.1 1.8 8.3 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 ORX89043.1 - 0.013 14.1 0.0 0.015 13.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) MotA_activ PF09114.10 ORX89043.1 - 0.015 15.4 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.14 ORX89043.1 - 0.05 13.3 0.9 0.18 11.4 0.9 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 ORX89043.1 - 0.083 13.2 0.1 16 5.9 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Spore_III_AB PF09548.10 ORX89043.1 - 0.18 11.9 0.5 0.3 11.2 0.5 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RloB PF13707.6 ORX89043.1 - 0.25 11.5 1.7 1.3 9.2 0.3 2.1 1 1 1 2 2 2 0 RloB-like protein SapB_1 PF05184.15 ORX89043.1 - 0.28 11.3 2.9 29 4.8 0.0 3.4 4 0 0 4 4 4 0 Saposin-like type B, region 1 2-oxoacid_dh PF00198.23 ORX89044.1 - 9e-71 238.0 0.0 1.3e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORX89044.1 - 6.7e-20 70.7 0.1 1.7e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORX89044.1 - 0.00089 19.5 3.7 0.5 10.8 0.1 2.8 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORX89044.1 - 0.0011 18.7 0.3 0.0049 16.7 0.3 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 ORX89044.1 - 0.031 13.5 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Cation_efflux PF01545.21 ORX89045.1 - 1.8e-50 171.5 14.6 2.3e-50 171.1 14.6 1.1 1 0 0 1 1 1 1 Cation efflux family Triabin PF03973.13 ORX89045.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Triabin PhaG_MnhG_YufB PF03334.14 ORX89045.1 - 1.4 9.2 7.4 3.4 8.0 0.9 2.6 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Anoctamin PF04547.12 ORX89045.1 - 2 7.2 6.5 0.33 9.7 0.6 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel TPR_17 PF13431.6 ORX89046.1 - 2.4e-06 27.5 1.6 0.043 14.2 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89046.1 - 0.00019 21.9 2.2 9.1 7.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89046.1 - 0.0013 18.5 15.1 1.3 9.0 0.1 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89046.1 - 0.0036 17.0 2.9 3.3 7.5 0.0 4.6 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.17 ORX89046.1 - 0.11 12.6 14.3 13 6.1 0.4 7.0 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89046.1 - 0.21 11.9 9.1 1.1 9.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89046.1 - 0.27 11.9 3.0 40 5.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat GST_C_3 PF14497.6 ORX89047.1 - 3.9e-18 65.5 0.1 4.8e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX89047.1 - 4.3e-06 26.9 0.0 8.2e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX89047.1 - 0.0018 18.3 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX89047.1 - 0.0049 17.4 0.0 0.0067 17.0 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AOX PF01786.17 ORX89048.1 - 8.6e-84 280.4 0.4 1e-83 280.1 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF3194 PF11419.8 ORX89048.1 - 0.12 12.7 0.9 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) Ribosomal_L37e PF01907.19 ORX89049.1 - 1.1e-27 96.0 13.0 1.7e-27 95.3 13.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX89049.1 - 0.0059 16.6 1.6 0.0093 16.0 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORX89049.1 - 0.034 14.2 0.9 0.047 13.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORX89049.1 - 0.22 11.0 3.6 2.3 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORX89049.1 - 0.68 9.9 5.4 1.1 9.2 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 ORX89049.1 - 2.3 7.6 5.3 1.1 8.7 3.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) CKS PF01111.19 ORX89051.1 - 1.6e-35 121.2 1.0 2.2e-35 120.7 1.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1749 PF08538.10 ORX89052.1 - 4.8e-75 252.4 0.1 5.5e-75 252.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 ORX89052.1 - 5.2e-06 26.3 0.1 4.6e-05 23.2 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX89052.1 - 4.7e-05 22.8 0.0 0.0002 20.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX89052.1 - 0.00021 22.0 0.0 0.00025 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 ORX89052.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 ORX89052.1 - 0.036 13.4 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 ORX89052.1 - 0.043 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.15 ORX89052.1 - 0.088 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cyclin PF08613.11 ORX89053.1 - 1.5e-07 31.9 0.4 2.4e-07 31.3 0.4 1.4 1 0 0 1 1 1 1 Cyclin Sel_put PF04328.13 ORX89053.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Selenoprotein, putative F-box-like PF12937.7 ORX89054.1 - 2.6e-09 36.8 0.3 3.3e-09 36.5 0.3 1.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX89054.1 - 0.059 13.3 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 F-box domain Peptidase_S9 PF00326.21 ORX89055.1 - 1.7e-56 191.1 0.3 2.7e-56 190.4 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORX89055.1 - 1.2e-07 31.5 10.4 0.058 13.3 0.0 5.2 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 ORX89055.1 - 6.3e-05 22.8 2.2 0.026 14.2 0.3 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.12 ORX89055.1 - 0.00068 18.4 0.0 0.0048 15.6 0.0 1.9 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 ORX89055.1 - 0.00074 19.2 0.5 0.0017 18.1 0.5 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 ORX89055.1 - 0.013 15.1 0.8 2 7.9 0.0 2.4 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ORX89055.1 - 0.058 14.0 0.2 0.23 12.0 0.2 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 ORX89055.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PCC_BT PF18140.1 ORX89055.1 - 0.14 12.5 0.1 0.7 10.2 0.0 2.1 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain DUF4449 PF14613.6 ORX89056.1 - 5.8e-06 26.5 1.2 5.8e-06 26.5 1.2 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) DUF668 PF05003.12 ORX89056.1 - 0.69 10.4 2.6 1.8 9.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF668) DUF883 PF05957.13 ORX89056.1 - 9.3 6.9 15.6 28 5.4 0.4 5.1 3 2 0 5 5 5 0 Bacterial protein of unknown function (DUF883) PHO4 PF01384.20 ORX89057.1 - 0.12 11.4 0.5 0.16 11.0 0.5 1.3 1 0 0 1 1 1 0 Phosphate transporter family Claudin_2 PF13903.6 ORX89057.1 - 0.32 10.7 5.6 4.7 6.9 0.0 2.5 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction PQ-loop PF04193.14 ORX89059.1 - 0.1 12.4 3.1 0.41 10.5 0.6 2.7 2 0 0 2 2 2 0 PQ loop repeat Cu-oxidase PF00394.22 ORX89060.1 - 8.7e-39 133.2 0.2 4.8e-37 127.5 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX89060.1 - 3.4e-31 107.7 2.8 3.6e-31 107.7 0.2 2.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX89060.1 - 1.2e-28 99.6 7.4 8.4e-28 96.8 0.8 3.6 2 2 0 2 2 2 1 Multicopper oxidase DUF2045 PF09741.9 ORX89061.1 - 1.2e-46 159.0 0.0 1.5e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Mdv1 PF11542.8 ORX89061.1 - 0.19 11.7 0.3 8.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial division protein 1 TMEM141 PF15110.6 ORX89062.1 - 0.037 14.6 0.1 0.1 13.2 0.0 1.8 2 0 0 2 2 2 0 TMEM141 protein family zf-Mss51 PF13824.6 ORX89062.1 - 0.039 14.0 0.5 0.09 12.9 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 APH PF01636.23 ORX89063.1 - 6.2e-09 36.1 0.0 9.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EIIA-man PF03610.16 ORX89063.1 - 0.18 12.1 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 PTS system fructose IIA component EcKinase PF02958.20 ORX89063.1 - 0.21 10.9 0.1 2.1 7.6 0.0 2.4 2 1 0 2 2 2 0 Ecdysteroid kinase Abhydrolase_3 PF07859.13 ORX89064.1 - 3.4e-31 108.7 0.0 4.2e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX89064.1 - 8.5e-13 47.9 0.0 1.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 ORX89064.1 - 9.7e-06 25.3 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORX89064.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORX89064.1 - 0.097 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DNA_pol_A_exo1 PF01612.20 ORX89065.1 - 4.6e-15 55.8 0.0 8.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease 3-dmu-9_3-mt PF06983.13 ORX89065.1 - 0.12 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase SCP2 PF02036.17 ORX89066.1 - 5.1e-09 36.5 0.0 8.2e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 SCP-2 sterol transfer family ADH_N PF08240.12 ORX89067.1 - 4e-24 84.6 1.5 1e-23 83.3 1.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX89067.1 - 3.8e-22 78.6 0.1 6.2e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX89067.1 - 0.002 17.4 0.4 0.0038 16.6 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.16 ORX89067.1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MinC_C PF03775.16 ORX89067.1 - 0.049 13.6 0.2 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Homeodomain PF00046.29 ORX89068.1 - 3.3e-16 58.9 7.3 4.1e-16 58.6 7.3 1.1 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORX89068.1 - 0.0012 18.5 0.8 0.27 11.1 0.1 2.2 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 ORX89068.1 - 0.021 14.9 0.8 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 ORX89068.1 - 0.025 14.5 2.6 0.054 13.4 0.1 2.4 2 1 1 3 3 3 0 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX89068.1 - 0.025 14.4 0.2 0.069 13.0 0.1 1.8 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MRP-L20 PF12824.7 ORX89068.1 - 0.03 14.5 2.3 0.035 14.3 2.3 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 IPPT PF01715.17 ORX89068.1 - 0.058 13.2 1.7 0.069 12.9 1.7 1.0 1 0 0 1 1 1 0 IPP transferase SAM_Exu PF18609.1 ORX89068.1 - 0.061 13.4 0.5 0.084 13.0 0.5 1.2 1 0 0 1 1 1 0 Exuperantia SAM-like domain Exo84_C PF16528.5 ORX89068.1 - 0.11 12.3 1.9 0.12 12.2 1.9 1.1 1 0 0 1 1 1 0 Exocyst component 84 C-terminal BrkDBD PF09607.10 ORX89068.1 - 0.13 12.1 2.0 0.2 11.4 1.8 1.6 1 1 0 1 1 1 0 Brinker DNA-binding domain RRF PF01765.19 ORX89068.1 - 0.17 11.8 3.1 0.19 11.7 3.1 1.0 1 0 0 1 1 1 0 Ribosome recycling factor VWA_2 PF13519.6 ORX89069.1 - 6.9e-08 33.1 0.0 2.3e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 ORX89069.1 - 3.7e-07 28.7 0.5 3.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 ORX89069.1 - 2.1e-06 27.2 0.0 4.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain IFN-gamma PF00714.17 ORX89069.1 - 0.27 11.1 2.4 1.5 8.7 0.7 2.7 1 1 1 2 2 2 0 Interferon gamma E1-E2_ATPase PF00122.20 ORX89070.1 - 1e-20 74.0 1.1 1.3e-20 73.7 0.1 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 ORX89070.1 - 5.6e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Borrelia_P13 PF05628.12 ORX89070.1 - 0.004 17.1 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Borrelia membrane protein P13 PAF-AH_p_II PF03403.13 ORX89071.1 - 7.6e-10 37.8 0.0 9.6e-10 37.5 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX89071.1 - 7.3e-05 21.8 0.0 9.4e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme MIP PF00230.20 ORX89072.1 - 2.1e-55 187.9 11.5 2.5e-55 187.6 11.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 ORX89073.1 - 1.4e-45 155.8 42.3 1.2e-44 152.7 42.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX89073.1 - 7.4e-18 64.3 19.1 9.1e-18 64.0 19.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX89073.1 - 2.9e-07 29.7 14.5 2.9e-07 29.7 14.5 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORX89073.1 - 1.6e-06 27.2 10.1 1.8e-05 23.8 6.2 2.3 2 0 0 2 2 2 2 MFS_1 like family Ceramidase_alk PF04734.13 ORX89074.1 - 1.4e-230 766.2 0.0 1.7e-230 766.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ORX89074.1 - 9.9e-53 178.4 0.2 1.5e-52 177.8 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RANK_CRD_2 PF18278.1 ORX89074.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Taeniidae_ag PF05596.11 ORX89074.1 - 0.073 13.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Taeniidae antigen Topoisom_bac PF01131.20 ORX89075.1 - 2.2e-107 359.6 0.0 2.6e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 ORX89075.1 - 1.5e-17 63.7 0.0 2.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain NUDIX PF00293.28 ORX89076.1 - 0.0056 16.7 0.1 0.0063 16.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain PHD PF00628.29 ORX89077.1 - 3.1e-08 33.4 16.3 6.5e-08 32.3 16.3 1.6 1 0 0 1 1 1 1 PHD-finger Aminotran_3 PF00202.21 ORX89078.1 - 4.7e-116 387.8 0.0 5.5e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX89078.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II Serine_rich PF08824.10 ORX89078.1 - 0.039 14.0 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain Aminotran_3 PF00202.21 ORX89080.1 - 2.9e-62 210.6 0.0 3.5e-46 157.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III Serine_rich PF08824.10 ORX89080.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain Tmemb_18A PF09771.9 ORX89081.1 - 1.3 9.4 4.4 1.5 9.2 1.2 2.2 1 1 1 2 2 2 0 Transmembrane protein 188 HMGL-like PF00682.19 ORX89082.1 - 2.7e-78 263.2 0.2 4.4e-78 262.5 0.2 1.3 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 ORX89082.1 - 0.016 15.8 0.1 0.033 14.7 0.1 1.6 1 0 0 1 1 1 0 FliG N-terminal domain FAD-SLDH PF12318.8 ORX89082.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase zf-MYND PF01753.18 ORX89083.1 - 9.8e-07 28.8 19.9 2.3e-06 27.6 19.9 1.7 1 1 0 1 1 1 1 MYND finger Complex1_LYR_2 PF13233.6 ORX89084.1 - 9.7e-17 61.5 0.8 1.2e-16 61.2 0.8 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ORX89084.1 - 3.5e-14 52.6 0.1 4.9e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORX89084.1 - 0.11 13.1 0.3 0.54 10.9 0.1 2.0 1 1 1 3 3 3 0 Complex1_LYR-like RNA_pol_Rpb1_5 PF04998.17 ORX89086.1 - 2.7e-96 322.1 0.0 1.4e-95 319.7 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORX89086.1 - 2.5e-66 223.0 0.0 4.8e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORX89086.1 - 6.6e-38 130.1 0.0 1.7e-37 128.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 ORX89086.1 - 4e-30 105.2 3.9 1.7e-28 99.9 3.9 3.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 ORX89086.1 - 6.2e-25 87.2 0.5 6.2e-25 87.2 0.5 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Mito_carr PF00153.27 ORX89087.1 - 1.1e-68 227.2 4.8 4.6e-25 87.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 ORX89087.1 - 0.0083 15.4 0.1 0.15 11.2 0.1 2.0 2 0 0 2 2 2 1 Fuseless Mito_carr PF00153.27 ORX89088.1 - 1.1e-68 227.2 4.8 4.6e-25 87.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 ORX89088.1 - 0.0083 15.4 0.1 0.15 11.2 0.1 2.0 2 0 0 2 2 2 1 Fuseless Cyclin_N PF00134.23 ORX89089.1 - 3.5e-14 52.6 0.0 7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Flp_N PF03930.14 ORX89089.1 - 0.014 15.4 0.2 0.028 14.4 0.2 1.5 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus TFIIB PF00382.19 ORX89089.1 - 0.034 14.2 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORX89089.1 - 0.042 13.9 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF3456 PF11938.8 ORX89089.1 - 0.077 13.5 0.2 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP CHCH PF06747.13 ORX89090.1 - 3.8e-06 26.9 8.8 5.3e-06 26.4 8.8 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 ORX89090.1 - 5.9e-05 23.3 9.7 7.6e-05 22.9 9.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CX9C PF16860.5 ORX89090.1 - 0.00011 22.2 3.5 0.00016 21.6 3.5 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PLA2G12 PF06951.11 ORX89091.1 - 1.1e-07 31.9 8.2 1.7e-07 31.3 8.2 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Mo25 PF08569.11 ORX89092.1 - 4.2e-121 404.3 1.1 4.7e-121 404.1 1.1 1.0 1 0 0 1 1 1 1 Mo25-like GDC-P PF02347.16 ORX89093.1 - 9.9e-193 640.8 3.7 6.6e-182 605.1 0.1 3.3 4 0 0 4 4 4 2 Glycine cleavage system P-protein Synaptobrevin PF00957.21 ORX89093.1 - 2.8e-29 100.7 2.2 6.8e-29 99.5 2.2 1.7 1 0 0 1 1 1 1 Synaptobrevin Aminotran_5 PF00266.19 ORX89093.1 - 7.9e-06 25.1 0.1 1.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORX89093.1 - 0.0006 19.2 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORX89093.1 - 0.1 11.8 0.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II MCU PF04678.13 ORX89093.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1805 PF08827.11 ORX89093.1 - 0.14 12.5 0.1 0.93 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) GDC-P PF02347.16 ORX89094.1 - 7.8e-151 502.7 3.6 1.8e-139 465.3 0.1 3.7 4 1 0 4 4 4 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ORX89094.1 - 5.6e-06 25.6 0.1 1.2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORX89094.1 - 0.00045 19.6 0.1 0.00082 18.7 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF1805 PF08827.11 ORX89094.1 - 0.041 14.2 0.1 0.68 10.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Aminotran_1_2 PF00155.21 ORX89094.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II Cornifin PF02389.15 ORX89095.1 - 1.1e-10 41.8 66.2 1.1e-06 28.9 33.7 2.5 1 1 1 2 2 2 2 Cornifin (SPRR) family CBM_19 PF03427.13 ORX89095.1 - 1.8 8.6 19.9 0.063 13.3 9.4 3.6 2 1 1 3 3 3 0 Carbohydrate binding domain (family 19) Cornifin PF02389.15 ORX89096.1 - 4.8e-17 62.4 123.0 2.3e-08 34.3 47.8 3.7 1 1 3 4 4 4 4 Cornifin (SPRR) family CBM_19 PF03427.13 ORX89096.1 - 0.0071 16.3 6.7 0.0071 16.3 6.7 3.6 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) Choline_kinase PF01633.20 ORX89097.1 - 1.9e-55 187.8 0.1 1e-54 185.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORX89097.1 - 5e-08 33.2 0.0 8.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORX89097.1 - 0.00034 20.0 0.1 0.16 11.2 0.1 2.5 2 1 1 3 3 3 2 Ecdysteroid kinase SPATA1_C PF15743.5 ORX89097.1 - 0.18 11.9 0.4 0.94 9.5 0.1 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus CAP PF00188.26 ORX89098.1 - 2.8e-16 60.5 0.0 6e-16 59.4 0.0 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX89099.1 - 3.8e-16 60.1 0.0 8.2e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family FerI PF08151.12 ORX89100.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 FerI (NUC094) domain Wzz PF02706.15 ORX89102.1 - 0.0019 18.5 0.1 0.0019 18.5 0.1 2.3 3 0 0 3 3 3 1 Chain length determinant protein MFS_1 PF07690.16 ORX89102.1 - 0.0042 16.1 14.3 0.017 14.0 5.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2374 PF09574.10 ORX89102.1 - 0.014 15.2 0.2 0.034 14.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Lipase_3 PF01764.25 ORX89103.1 - 7.3e-33 113.4 0.0 2.1e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 ORX89103.1 - 7.2e-05 22.4 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ORX89103.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 ORX89103.1 - 0.005 16.1 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX89103.1 - 0.014 16.0 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORX89103.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 ORX89103.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 ORX89103.1 - 0.18 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sterol_MT_C PF08498.10 ORX89104.1 - 2.1e-22 79.2 0.0 3.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ORX89104.1 - 5.8e-20 71.7 0.0 1e-17 64.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX89104.1 - 1.1e-15 58.1 0.0 7.8e-15 55.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX89104.1 - 1.3e-14 54.3 0.0 2.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX89104.1 - 1.2e-12 47.7 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORX89104.1 - 1.3e-12 47.9 0.0 2.9e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89104.1 - 7.9e-09 36.2 0.1 6.6e-08 33.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX89104.1 - 6.1e-08 32.3 0.0 2.6e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 ORX89104.1 - 0.037 13.6 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.19 ORX89104.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 ORX89104.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 N1221 PF07923.13 ORX89105.1 - 0.015 14.5 0.5 0.052 12.7 0.1 2.0 2 0 0 2 2 2 0 N1221-like protein EH_Signature PF15611.6 ORX89105.1 - 1.3 8.3 4.9 1.9 7.8 1.6 2.2 2 1 0 3 3 3 0 EH_Signature domain DUF3730 PF12530.8 ORX89106.1 - 2e-13 50.5 0.2 2.1e-12 47.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) Thioredoxin_14 PF18402.1 ORX89106.1 - 0.042 13.8 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain DUF4071 PF13281.6 ORX89106.1 - 0.076 12.1 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Per1 PF04080.13 ORX89107.1 - 3.4e-98 328.5 14.1 4e-98 328.2 14.1 1.0 1 0 0 1 1 1 1 Per1-like family DUF3522 PF12036.8 ORX89107.1 - 8.5e-05 22.9 3.5 0.00034 21.0 3.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) 7TM-7TMR_HD PF07698.11 ORX89107.1 - 0.0059 16.4 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase NAP PF00956.18 ORX89108.1 - 2.5e-91 305.6 6.6 3.7e-91 305.0 6.6 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Acatn PF13000.7 ORX89109.1 - 1.3e-166 555.4 27.9 4.5e-87 292.8 11.8 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DHQ_synthase PF01761.20 ORX89109.1 - 0.18 11.0 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase Ribosomal_L36e PF01158.18 ORX89110.1 - 1e-42 144.2 7.4 1.2e-42 144.1 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mago-bind PF09282.10 ORX89110.1 - 0.2 11.6 1.7 7.4 6.5 0.2 2.8 2 0 0 2 2 2 0 Mago binding Pkinase PF00069.25 ORX89112.1 - 4.2e-65 219.7 0.0 7.2e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89112.1 - 3.8e-29 101.8 0.0 5.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORX89112.1 - 2.5e-11 44.1 1.1 6.1e-11 42.8 0.5 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 ORX89112.1 - 7.2e-05 22.2 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.24 ORX89112.1 - 0.00017 21.5 0.5 0.00067 19.6 0.2 2.1 2 0 0 2 2 2 1 PX domain Pkinase_fungal PF17667.1 ORX89112.1 - 0.00024 20.0 0.0 0.00059 18.7 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX89112.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORX89112.1 - 0.0029 17.3 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX89112.1 - 0.011 14.8 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Acetyltransf_1 PF00583.25 ORX89113.1 - 5.6e-13 49.2 0.3 1.1e-12 48.2 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX89113.1 - 8.6e-11 41.9 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX89113.1 - 8.6e-11 42.1 0.1 1.6e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX89113.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORX89113.1 - 1.1e-05 25.5 0.0 0.0001 22.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX89113.1 - 2.9e-05 24.1 0.1 8.2e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ORX89113.1 - 0.00012 22.8 0.2 0.00015 22.5 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORX89113.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.7 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 ORX89113.1 - 0.01 16.0 0.1 0.024 14.8 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ORX89113.1 - 0.045 13.9 0.0 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF624 PF04854.14 ORX89113.1 - 0.046 13.8 0.1 0.091 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Peptidase_S9 PF00326.21 ORX89115.1 - 1.1e-56 191.7 0.5 1.8e-56 191.0 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORX89115.1 - 3.1e-09 36.5 10.4 0.011 15.7 0.1 5.0 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat AXE1 PF05448.12 ORX89115.1 - 6.2e-06 25.1 0.0 0.00028 19.7 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lactonase PF10282.9 ORX89115.1 - 0.0042 16.4 0.1 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Esterase PF00756.20 ORX89115.1 - 0.011 15.4 0.3 0.047 13.3 0.3 2.0 1 1 0 1 1 1 0 Putative esterase AAA PF00004.29 ORX89116.1 - 1.1e-11 45.3 0.1 5.7e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORX89116.1 - 1.6e-05 25.0 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORX89116.1 - 1.8e-05 24.5 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 ORX89116.1 - 3.7e-05 23.7 0.0 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 ORX89116.1 - 0.00013 22.2 0.1 0.0034 17.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 ORX89116.1 - 0.00056 20.2 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 ORX89116.1 - 0.0017 18.4 0.0 0.0052 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX89116.1 - 0.0071 16.7 0.1 0.048 14.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORX89116.1 - 0.0096 16.5 0.1 0.096 13.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORX89116.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 ORX89116.1 - 0.033 13.8 0.1 0.75 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ORX89116.1 - 0.039 13.7 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX89116.1 - 0.064 13.2 0.7 0.17 11.8 0.3 1.9 1 1 1 2 2 2 0 NTPase NB-ARC PF00931.22 ORX89116.1 - 0.086 12.0 0.1 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 ORX89116.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 ORX89116.1 - 0.096 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 ORX89116.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 ORX89116.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORX89116.1 - 0.19 11.0 0.3 0.88 8.9 0.0 2.2 2 1 1 3 3 3 0 KaiC AAA_19 PF13245.6 ORX89116.1 - 0.55 10.6 1.7 1.6 9.1 0.4 2.2 2 1 1 3 3 3 0 AAA domain Cyclin PF08613.11 ORX89117.1 - 1.1e-10 42.1 0.0 1.8e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Cyclin CKS PF01111.19 ORX89118.1 - 1.6e-27 95.6 4.5 8.9e-27 93.2 4.5 2.0 1 1 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Carboxyl_trans PF01039.22 ORX89119.1 - 2.3e-194 646.7 0.7 2.7e-194 646.4 0.7 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ORX89119.1 - 0.002 17.7 0.1 0.054 13.0 0.0 2.6 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) CPSase_L_D2 PF02786.17 ORX89120.1 - 5.3e-82 274.4 0.2 9.7e-82 273.6 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORX89120.1 - 6.6e-46 155.4 0.0 1.6e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORX89120.1 - 1.4e-33 115.2 0.0 4.2e-33 113.7 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 ORX89120.1 - 3.5e-30 104.9 0.0 1.1e-29 103.4 0.0 1.9 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 ORX89120.1 - 8.5e-14 51.1 1.1 8.5e-14 51.1 1.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORX89120.1 - 5e-09 36.0 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORX89120.1 - 6.6e-08 32.3 0.2 1.9e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 ORX89120.1 - 0.00015 21.4 0.1 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 ORX89120.1 - 0.0022 18.7 1.3 0.92 10.2 0.1 3.6 3 0 0 3 3 3 1 HlyD family secretion protein ATP-grasp_3 PF02655.14 ORX89120.1 - 0.0026 17.8 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 ORX89120.1 - 0.015 14.7 0.2 0.15 11.5 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORX89120.1 - 0.089 12.6 0.3 0.57 10.1 0.1 2.4 2 1 1 3 3 3 0 Biotin-lipoyl like LpxI_N PF17930.1 ORX89120.1 - 0.14 12.0 0.4 15 5.5 0.0 3.2 3 0 0 3 3 3 0 LpxI N-terminal domain RnfC_N PF13375.6 ORX89120.1 - 0.5 10.3 2.6 0.65 10.0 0.2 2.4 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain Ribosomal_L37e PF01907.19 ORX89121.1 - 9.9e-28 96.1 13.0 1.7e-27 95.3 13.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX89121.1 - 0.0058 16.6 1.6 0.009 16.0 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORX89121.1 - 0.032 14.2 0.9 0.046 13.8 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORX89121.1 - 0.21 11.0 3.6 2.2 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORX89121.1 - 0.65 9.9 5.4 1.1 9.2 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L30 PF00327.20 ORX89122.1 - 7.1e-13 48.2 0.4 1.3e-12 47.4 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Bac_DNA_binding PF00216.21 ORX89122.1 - 0.083 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial DNA-binding protein Homeodomain PF00046.29 ORX89123.1 - 3.9e-15 55.4 4.6 4.9e-15 55.1 4.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX89123.1 - 3.2e-05 23.7 0.1 6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 ORX89123.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain 2Fe-2S_thioredx PF01257.19 ORX89123.1 - 0.04 13.8 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Terminase_5 PF06056.12 ORX89123.1 - 0.049 13.5 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Ribosomal_60s PF00428.19 ORX89126.1 - 6.8e-27 93.9 12.6 7.7e-27 93.7 12.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein MT PF12777.7 ORX89126.1 - 0.11 11.5 0.6 0.12 11.3 0.6 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Nuc_sug_transp PF04142.15 ORX89127.1 - 6.3e-110 367.2 21.5 7.1e-110 367.1 21.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORX89127.1 - 9.1e-07 28.4 19.6 1.2e-06 28.0 18.5 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORX89127.1 - 2.2e-05 24.7 30.3 0.00049 20.3 5.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 ORX89127.1 - 3.6e-05 23.5 6.5 6.2e-05 22.7 5.9 1.8 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 ORX89127.1 - 0.0021 17.4 21.1 0.0043 16.3 21.1 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DMT_6 PF04342.12 ORX89127.1 - 1.1 9.5 8.7 3.9 7.7 1.1 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Ribosomal_L26 PF16906.5 ORX89128.1 - 5.7e-37 126.1 3.5 7.4e-37 125.7 3.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORX89128.1 - 7.5e-10 38.4 3.4 7.5e-10 38.4 3.4 1.9 2 1 0 2 2 2 1 KOW motif SPT2 PF08243.11 ORX89129.1 - 2.5e-18 66.6 13.0 2.5e-18 66.6 13.0 3.5 2 1 1 3 3 3 1 SPT2 chromatin protein HMG_box PF00505.19 ORX89130.1 - 2.9e-19 69.2 3.2 3.2e-19 69.1 3.2 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX89130.1 - 2.9e-08 34.2 1.7 3.2e-08 34.0 1.7 1.0 1 0 0 1 1 1 1 HMG-box domain KORA PF16509.5 ORX89130.1 - 0.012 15.9 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Mo-co_dimer PF03404.16 ORX89130.1 - 0.058 13.4 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain PRTase_2 PF15609.6 ORX89130.1 - 0.13 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase Pkinase PF00069.25 ORX89131.1 - 1.8e-55 188.2 0.0 2.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89131.1 - 6.2e-25 88.0 0.0 9.4e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX89131.1 - 0.0049 16.8 0.0 0.029 14.3 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX89131.1 - 0.0079 15.6 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 ORX89131.1 - 0.028 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 ORX89131.1 - 0.033 13.8 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase FTA2 PF13095.6 ORX89131.1 - 0.11 12.0 0.3 0.49 10.0 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX89131.1 - 0.22 11.1 1.8 3.7 7.1 0.0 2.4 1 1 0 2 2 2 0 RIO1 family CRAL_TRIO PF00650.20 ORX89132.1 - 1.4e-20 73.6 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORX89132.1 - 6e-10 39.4 0.0 9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Polysacc_deac_1 PF01522.21 ORX89134.1 - 2.7e-27 95.1 0.0 3.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX89134.1 - 6.5e-07 29.7 19.4 1e-06 29.1 19.4 1.3 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 ORX89134.1 - 0.0037 16.9 0.3 0.0092 15.7 0.3 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX89134.1 - 0.0044 16.3 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF1769 PF08588.10 ORX89135.1 - 5e-22 77.9 0.1 1.2e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) TPR_MLP1_2 PF07926.12 ORX89136.1 - 2.3e-06 27.7 26.4 0.0047 17.0 5.7 2.9 1 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 ORX89136.1 - 0.00025 21.1 30.6 0.014 15.4 19.8 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NUDE_C PF04880.13 ORX89136.1 - 0.00034 21.1 5.3 0.00034 21.1 5.3 2.5 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region Spc7 PF08317.11 ORX89136.1 - 0.00083 18.3 26.0 0.0013 17.7 23.0 1.9 1 1 1 2 2 2 1 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 ORX89136.1 - 0.0016 18.2 3.8 0.0016 18.2 3.8 5.1 7 0 0 7 7 4 1 Viral A-type inclusion protein repeat CENP-H PF05837.12 ORX89136.1 - 0.0055 17.1 10.7 0.0055 17.1 10.7 2.2 1 1 1 2 2 2 1 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 ORX89136.1 - 0.0075 17.1 25.9 0.022 15.6 10.7 2.7 1 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 ORX89136.1 - 0.0091 15.7 25.3 0.047 13.5 6.3 4.1 2 1 2 4 4 4 2 Septum formation initiator DHR10 PF18595.1 ORX89136.1 - 0.018 15.1 29.8 0.65 10.1 16.0 2.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain BRE1 PF08647.11 ORX89136.1 - 0.021 14.9 28.3 0.041 14.0 3.7 2.9 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 ORX89136.1 - 0.021 15.4 20.6 0.1 13.2 1.6 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 ORX89136.1 - 0.026 13.8 20.7 0.039 13.3 0.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) CdvA PF18822.1 ORX89136.1 - 0.026 14.3 21.4 0.033 14.0 6.4 3.0 1 1 1 3 3 3 0 CdvA-like coiled-coil domain TMF_DNA_bd PF12329.8 ORX89136.1 - 0.028 14.4 1.0 0.028 14.4 1.0 3.9 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 ORX89136.1 - 0.031 14.3 23.8 0.39 10.8 3.2 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 ORX89136.1 - 0.042 13.4 23.3 0.18 11.4 9.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein WXG100 PF06013.12 ORX89136.1 - 0.042 14.1 9.0 2.2 8.6 1.3 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG bZIP_2 PF07716.15 ORX89136.1 - 0.051 13.7 7.7 0.051 13.7 7.7 4.4 4 1 1 5 5 4 0 Basic region leucine zipper GAS PF13851.6 ORX89136.1 - 0.073 12.4 27.2 0.11 11.8 9.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 ORX89136.1 - 0.081 11.3 26.2 0.34 9.2 9.1 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein HOOK PF05622.12 ORX89136.1 - 0.094 10.9 22.0 0.14 10.3 22.0 1.2 1 0 0 1 1 1 0 HOOK protein ATG16 PF08614.11 ORX89136.1 - 0.15 12.3 30.3 0.59 10.3 17.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 ORX89136.1 - 0.15 11.9 15.4 0.87 9.5 0.1 3.8 2 1 3 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3584 PF12128.8 ORX89136.1 - 0.15 9.5 17.9 0.21 9.1 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4140 PF13600.6 ORX89136.1 - 0.17 12.4 15.7 1.7 9.1 1.0 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 ORX89136.1 - 0.2 12.0 24.6 3.7 7.9 15.6 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 ORX89136.1 - 0.22 12.0 33.6 0.3 11.5 2.9 3.9 2 2 2 4 4 4 0 Cell division protein ZapB SHE3 PF17078.5 ORX89136.1 - 0.27 10.9 22.3 0.33 10.6 18.5 2.5 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 TSNAXIP1_N PF15739.5 ORX89136.1 - 0.31 11.4 19.0 0.74 10.2 3.4 3.2 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus BST2 PF16716.5 ORX89136.1 - 0.32 11.6 24.0 1.9 9.1 3.2 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 HALZ PF02183.18 ORX89136.1 - 0.35 11.1 28.1 0.12 12.6 7.9 4.0 4 1 0 4 4 3 0 Homeobox associated leucine zipper Occludin_ELL PF07303.13 ORX89136.1 - 0.43 11.3 16.3 0.75 10.5 4.5 2.8 1 1 1 2 2 2 0 Occludin homology domain Lectin_N PF03954.14 ORX89136.1 - 0.43 10.3 11.2 2.1 8.1 0.8 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain YlqD PF11068.8 ORX89136.1 - 0.45 10.9 18.7 2.3 8.6 10.0 2.2 1 1 1 2 2 2 0 YlqD protein THP2 PF09432.10 ORX89136.1 - 0.46 10.6 11.1 0.45 10.6 5.0 2.2 1 1 1 2 2 2 0 Tho complex subunit THP2 DASH_Dam1 PF08653.10 ORX89136.1 - 0.51 10.2 8.8 23 4.9 0.1 3.5 3 1 0 3 3 3 0 DASH complex subunit Dam1 bZIP_1 PF00170.21 ORX89136.1 - 0.51 10.5 27.4 0.4 10.8 7.4 4.2 2 1 2 4 4 4 0 bZIP transcription factor Golgin_A5 PF09787.9 ORX89136.1 - 0.57 9.6 26.6 0.23 10.9 9.3 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 ORX89136.1 - 0.76 10.2 19.1 1.4 9.4 2.7 4.4 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) Hormone_1 PF00103.20 ORX89136.1 - 0.89 9.2 10.7 1.5 8.5 2.4 2.4 1 1 1 2 2 2 0 Somatotropin hormone family DUF4618 PF15397.6 ORX89136.1 - 0.98 8.8 22.6 0.56 9.6 2.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HAUS-augmin3 PF14932.6 ORX89136.1 - 1.2 8.7 24.6 0.19 11.3 13.1 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 ORX89136.1 - 1.4 8.7 31.0 3.8 7.3 11.3 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 ORX89136.1 - 1.5 8.9 9.8 5.5 7.0 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 ORX89136.1 - 1.5 9.3 20.0 3.4 8.2 1.6 3.7 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins IFT57 PF10498.9 ORX89136.1 - 1.5 7.7 20.1 8.7 5.2 10.9 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 APG6_N PF17675.1 ORX89136.1 - 1.5 9.3 34.6 12 6.4 14.0 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 ORX89136.1 - 1.6 9.1 3.7 34 4.8 1.2 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 ORX89136.1 - 1.7 9.1 24.7 2e+02 2.3 24.7 2.1 1 1 0 1 1 1 0 Fez1 DUF2353 PF09789.9 ORX89136.1 - 1.7 7.9 24.1 2.8 7.2 24.1 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF2203 PF09969.9 ORX89136.1 - 1.7 9.4 14.3 0.75 10.5 3.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4201 PF13870.6 ORX89136.1 - 1.7 8.3 23.5 8.7 6.0 7.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Med30 PF11315.8 ORX89136.1 - 2.1 8.6 14.2 0.21 11.8 4.9 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 BLOC1_2 PF10046.9 ORX89136.1 - 2.1 8.7 18.4 1.9 8.9 3.1 3.6 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Serine_rich PF08824.10 ORX89136.1 - 2.2 8.3 11.4 3 7.8 4.6 2.9 1 1 2 3 3 3 0 Serine rich protein interaction domain CENP-K PF11802.8 ORX89136.1 - 2.2 7.8 24.0 1.9 8.0 9.7 2.1 1 1 1 2 2 2 0 Centromere-associated protein K V_ATPase_I PF01496.19 ORX89136.1 - 2.5 5.9 15.1 4.3 5.1 15.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 ORX89136.1 - 3.1 8.2 28.5 12 6.4 15.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Lebercilin PF15619.6 ORX89136.1 - 3.4 7.3 28.6 4.5 6.9 7.7 2.7 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease JIP_LZII PF16471.5 ORX89136.1 - 3.5 7.9 30.4 2.3 8.4 1.4 3.7 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Seryl_tRNA_N PF02403.22 ORX89136.1 - 3.5 7.9 22.8 4.4 7.6 6.6 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DASH_Hsk3 PF08227.11 ORX89136.1 - 3.5 8.1 11.5 6.6 7.2 0.1 3.3 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like DUF724 PF05266.14 ORX89136.1 - 3.6 7.4 22.7 0.37 10.6 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF5595 PF18077.1 ORX89136.1 - 3.8 7.7 22.5 1.2 9.3 4.4 3.2 2 2 0 3 3 3 0 Domain of unknown function (DUF5595) TolA_bind_tri PF16331.5 ORX89136.1 - 4 7.6 20.8 7.4 6.7 10.2 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 ORX89136.1 - 4 6.7 15.3 13 5.0 15.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 ORX89136.1 - 4.5 5.8 21.5 1.6 7.3 6.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A UPF0242 PF06785.11 ORX89136.1 - 4.6 7.3 26.7 10 6.2 15.6 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 ORX89136.1 - 4.7 7.9 26.0 6.9 7.4 4.2 2.6 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ERM PF00769.19 ORX89136.1 - 5.4 6.8 33.4 5.4e+02 0.2 33.4 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.20 ORX89136.1 - 6.7 6.7 25.0 2.6 8.0 1.3 4.0 2 1 1 4 4 4 0 Prefoldin subunit Bestrophin PF01062.21 ORX89136.1 - 6.9 6.0 9.7 0.53 9.6 1.9 2.0 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel Fzo_mitofusin PF04799.13 ORX89136.1 - 7 6.2 16.4 5.6 6.5 4.6 2.7 1 1 2 3 3 3 0 fzo-like conserved region GrpE PF01025.19 ORX89136.1 - 7.6 6.2 25.6 11 5.7 4.6 3.0 1 1 2 3 3 3 0 GrpE TSC22 PF01166.18 ORX89136.1 - 7.9 6.9 15.2 21 5.5 4.1 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Transket_pyr PF02779.24 ORX89138.1 - 3.7e-45 153.8 0.0 5.3e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORX89138.1 - 1.2e-43 147.9 0.0 2.2e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ORX89138.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II YjeF_N PF03853.15 ORX89138.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Scramblase PF03803.15 ORX89141.1 - 2.3e-59 200.3 0.4 2.8e-59 200.1 0.4 1.0 1 0 0 1 1 1 1 Scramblase LOR PF04525.12 ORX89141.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 LURP-one-related PI-PLC-X PF00388.19 ORX89142.1 - 7.9e-60 200.7 0.0 1.4e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ORX89142.1 - 6.7e-42 142.5 0.0 1.4e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ORX89142.1 - 1.5e-16 60.5 0.0 3.2e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 ORX89142.1 - 4.9e-08 32.0 1.6 0.0042 16.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ORX89142.1 - 1.4e-07 31.8 1.9 1.8e-05 25.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORX89142.1 - 4.7e-06 26.1 4.1 0.26 11.3 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain GDPD PF03009.17 ORX89142.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_like PF09279.11 ORX89142.1 - 0.11 13.0 0.4 0.3 11.6 0.4 1.8 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like SPARC_Ca_bdg PF10591.9 ORX89142.1 - 0.18 12.1 0.7 0.37 11.1 0.3 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 ORX89142.1 - 0.25 11.2 1.1 2.5 8.0 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain pair Thymopoietin PF08198.11 ORX89143.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Thymopoietin protein DUF4093 PF13331.6 ORX89143.1 - 0.082 13.4 0.2 0.17 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) CBFD_NFYB_HMF PF00808.23 ORX89144.1 - 3.4e-19 68.9 2.4 4.8e-19 68.4 2.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX89144.1 - 1.5e-16 60.9 0.2 2e-16 60.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RPE65 PF03055.15 ORX89145.1 - 1.5e-87 294.7 0.0 1.9e-87 294.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein 2OG-FeII_Oxy_3 PF13640.6 ORX89146.1 - 2e-14 54.3 0.1 3.2e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 ORX89146.1 - 1.6e-07 30.8 0.0 1.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy_4 PF13661.6 ORX89146.1 - 0.013 16.1 0.1 0.026 15.2 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 ORX89146.1 - 0.16 12.2 0.1 29 4.8 0.0 2.7 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Lipase_3 PF01764.25 ORX89147.1 - 9.5e-36 122.8 0.0 2.5e-35 121.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX89147.1 - 2.6e-05 24.9 0.0 3.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORX89147.1 - 0.0061 16.1 0.6 0.049 13.2 0.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORX89147.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Zip PF02535.22 ORX89148.1 - 1.4 8.1 4.0 20 4.3 6.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Ras PF00071.22 ORX89149.1 - 2.4e-65 219.1 0.8 2.8e-65 218.9 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89149.1 - 2.5e-36 124.5 0.2 4e-36 123.9 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89149.1 - 4.9e-17 61.9 0.3 6.2e-17 61.6 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX89149.1 - 3.8e-06 26.5 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX89149.1 - 2e-05 24.1 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX89149.1 - 2.3e-05 24.4 0.4 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX89149.1 - 3.2e-05 24.0 0.0 5.8e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX89149.1 - 5.3e-05 22.8 0.7 0.00013 21.6 0.3 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORX89149.1 - 0.0092 16.4 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ORX89149.1 - 0.024 14.2 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 ORX89149.1 - 0.026 15.0 0.0 0.46 10.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX89149.1 - 0.035 14.4 0.1 0.066 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORX89149.1 - 0.041 13.9 0.0 0.066 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ORX89149.1 - 0.042 14.4 0.2 0.084 13.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 ORX89149.1 - 0.051 12.9 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 ORX89149.1 - 0.055 13.0 0.1 0.27 10.7 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 ORX89149.1 - 0.06 13.1 0.1 1.1 9.0 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ORX89149.1 - 0.065 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORX89149.1 - 0.074 12.5 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 ORX89149.1 - 0.14 11.7 0.2 1.2 8.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 ORX89150.1 - 2.9e-35 119.7 24.6 1.2e-07 32.3 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89150.1 - 1.8e-19 69.8 5.9 0.00065 19.9 0.1 5.3 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX89150.1 - 6.9e-08 32.2 0.1 5.2e-07 29.3 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 ORX89150.1 - 0.0011 18.0 1.4 0.28 10.1 0.7 3.4 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 ORX89150.1 - 0.0064 16.1 0.5 0.51 9.9 0.0 3.2 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Frtz PF11768.8 ORX89150.1 - 0.016 13.5 0.0 4 5.6 0.0 2.6 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 ORX89150.1 - 0.021 14.6 0.2 0.9 9.2 0.4 2.8 1 1 2 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.12 ORX89150.1 - 0.024 14.6 0.0 31 4.7 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Polysacc_deac_1 PF01522.21 ORX89151.1 - 7.9e-31 106.5 0.0 1.4e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX89151.1 - 3.8e-05 23.0 0.1 6.5e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX89151.1 - 0.0021 17.8 0.0 0.0087 15.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) zf-H2C2_2 PF13465.6 ORX89152.1 - 3.5e-12 46.1 11.3 3e-10 40.0 2.9 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX89152.1 - 8.9e-10 38.5 13.7 5.4e-07 29.7 4.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89152.1 - 9.2e-08 32.3 11.5 1.7e-05 25.2 2.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX89152.1 - 1.4e-05 25.2 3.0 0.0041 17.4 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 ORX89152.1 - 0.00041 20.2 1.1 0.52 10.3 0.1 2.1 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_6 PF13912.6 ORX89152.1 - 0.00051 20.0 8.3 0.067 13.2 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX89152.1 - 0.00053 20.3 4.2 0.31 11.5 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-trcl PF13451.6 ORX89152.1 - 0.0014 18.5 1.3 0.47 10.4 0.1 2.1 2 0 0 2 2 2 2 Probable zinc-ribbon domain zf-H2C2_5 PF13909.6 ORX89152.1 - 0.017 14.8 1.7 0.017 14.8 1.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2256 PF10013.9 ORX89152.1 - 0.026 14.6 2.1 2.4 8.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) PyrI_C PF02748.15 ORX89152.1 - 0.039 13.8 1.1 0.7 9.9 0.1 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 ORX89152.1 - 0.078 13.4 5.2 0.47 10.9 0.5 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORX89152.1 - 0.091 12.5 1.2 0.091 12.5 1.2 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORX89152.1 - 0.15 12.0 11.3 0.19 11.7 3.4 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type C1_4 PF07975.12 ORX89152.1 - 0.16 12.2 5.4 6.6 7.0 6.2 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-LYAR PF08790.11 ORX89152.1 - 0.21 11.5 4.7 3.1 7.8 0.3 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 ORX89152.1 - 0.37 11.0 8.9 4.2 7.6 1.9 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 ORX89152.1 - 0.41 10.8 5.4 1.5 9.0 0.5 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Velvet PF11754.8 ORX89153.1 - 2e-58 198.3 0.1 8.6e-36 124.1 0.1 2.0 1 1 1 2 2 2 2 Velvet factor Trypsin PF00089.26 ORX89154.1 - 1.2e-38 133.2 0.1 1.5e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 ORX89154.1 - 8e-08 32.7 0.0 2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 ORX89154.1 - 8.5e-05 23.5 0.0 0.00016 22.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pico_P1A PF02226.16 ORX89154.1 - 0.26 11.4 3.2 1.1 9.4 0.9 2.4 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) Pkinase PF00069.25 ORX89155.1 - 6.4e-69 232.3 1.2 4.2e-33 114.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89155.1 - 2.9e-28 98.9 0.4 1.5e-27 96.5 0.4 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX89155.1 - 0.0021 17.4 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Vps5 PF09325.10 ORX89156.1 - 9e-05 22.1 6.9 0.0001 21.9 6.9 1.0 1 0 0 1 1 1 1 Vps5 C terminal like Mod_r PF07200.13 ORX89156.1 - 0.00037 20.6 11.9 0.00039 20.5 11.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CHASE3 PF05227.13 ORX89156.1 - 0.035 14.0 0.2 0.053 13.4 0.2 1.3 1 1 0 1 1 1 0 CHASE3 domain FapA PF03961.13 ORX89156.1 - 0.1 11.2 9.0 0.11 11.1 9.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3958 PF13125.6 ORX89156.1 - 0.16 12.2 11.6 9.1 6.5 11.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) DUF848 PF05852.11 ORX89156.1 - 0.16 12.1 5.2 0.31 11.2 5.2 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF948 PF06103.11 ORX89156.1 - 0.27 11.5 2.0 1.4 9.3 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GLE1 PF07817.13 ORX89156.1 - 0.34 10.1 5.4 0.4 9.9 5.4 1.1 1 0 0 1 1 1 0 GLE1-like protein zf-C4pol PF14260.6 ORX89156.1 - 1.4 9.4 9.1 50 4.5 9.3 2.1 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF842 PF05811.13 ORX89157.1 - 0.002 17.8 0.2 0.016 14.9 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF842) PAN_3 PF08277.12 ORX89157.1 - 2.8 7.8 9.9 1.4 8.8 1.2 3.1 3 0 0 3 3 3 0 PAN-like domain Cyclin_N PF00134.23 ORX89158.1 - 1.1e-16 60.8 3.6 1.2e-15 57.4 0.5 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX89158.1 - 5.7e-05 23.2 0.6 0.022 14.8 0.2 2.6 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 ORX89158.1 - 0.00015 22.1 0.9 0.00049 20.4 0.3 2.3 2 1 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 ORX89158.1 - 0.00021 21.3 0.1 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Ribosomal_60s PF00428.19 ORX89159.1 - 5.6e-27 94.2 12.5 6.6e-27 93.9 12.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cyt-b5 PF00173.28 ORX89160.1 - 4.9e-10 39.4 0.1 6.8e-10 39.0 0.1 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HAD_2 PF13419.6 ORX89161.1 - 1.4e-26 93.7 0.0 1.7e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX89161.1 - 7.6e-17 62.3 0.1 3.2e-13 50.5 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX89161.1 - 1e-07 31.9 0.0 3.2e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORX89161.1 - 0.0011 19.3 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Con-6 PF10346.9 ORX89162.1 - 5.3e-08 32.8 0.9 1e-07 31.8 0.9 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Con-6 PF10346.9 ORX89163.1 - 1.6e-16 60.0 7.9 8e-08 32.2 1.3 2.4 2 0 0 2 2 2 2 Conidiation protein 6 DUF3933 PF13069.6 ORX89163.1 - 0.015 15.1 0.3 5 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) DotD PF16816.5 ORX89163.1 - 0.073 13.0 1.6 8.2 6.4 0.0 2.1 2 0 0 2 2 2 0 DotD protein Con-6 PF10346.9 ORX89164.1 - 7.3e-17 61.1 8.1 6.6e-08 32.5 0.8 2.4 2 0 0 2 2 2 2 Conidiation protein 6 DUF3933 PF13069.6 ORX89164.1 - 0.062 13.2 0.4 7.4 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Con-6 PF10346.9 ORX89165.1 - 5.6e-08 32.7 0.9 1e-07 31.8 0.9 1.5 1 0 0 1 1 1 1 Conidiation protein 6 adh_short_C2 PF13561.6 ORX89166.1 - 6.6e-52 176.4 0.0 8.7e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX89166.1 - 2.8e-49 167.2 0.1 3.7e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX89166.1 - 1.2e-08 35.1 0.1 1.9e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX89166.1 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX89166.1 - 0.00092 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 ORX89166.1 - 0.0015 18.8 0.2 0.0028 17.9 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORX89166.1 - 0.0016 18.3 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORX89166.1 - 0.0077 15.4 0.2 0.013 14.7 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 ORX89166.1 - 0.0096 15.3 0.2 0.019 14.3 0.2 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 ORX89166.1 - 0.037 14.0 0.9 0.12 12.4 0.5 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 ORX89166.1 - 0.046 14.2 1.1 0.18 12.3 1.1 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 ORX89166.1 - 0.053 12.5 0.1 0.076 12.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.8 ORX89166.1 - 0.076 12.8 0.4 0.37 10.6 0.4 2.2 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 ORX89166.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase zf-RING_2 PF13639.6 ORX89167.1 - 7.5e-15 55.0 10.3 7.3e-14 51.8 7.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX89167.1 - 4.5e-10 39.2 7.2 4.5e-10 39.2 7.2 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX89167.1 - 4e-08 32.9 5.8 4e-08 32.9 5.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORX89167.1 - 1.7e-07 31.0 6.4 1.7e-07 31.0 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX89167.1 - 3.8e-07 30.3 9.5 1.3e-06 28.6 9.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORX89167.1 - 5.4e-06 26.3 7.9 2.9e-05 24.0 5.0 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX89167.1 - 2.8e-05 24.0 5.2 2.8e-05 24.0 5.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORX89167.1 - 0.00017 21.3 12.6 0.00096 19.0 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORX89167.1 - 0.0016 18.5 7.4 0.0028 17.7 7.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 ORX89167.1 - 0.018 15.1 6.6 0.09 12.8 6.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger 8TM_micro PF17028.5 ORX89167.1 - 0.05 13.3 2.1 0.048 13.4 2.1 1.1 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain FANCL_C PF11793.8 ORX89167.1 - 0.1 12.8 11.1 0.65 10.2 11.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 ORX89167.1 - 0.16 12.1 5.4 0.086 13.0 3.3 1.5 1 1 0 1 1 1 0 KIAA1045 RING finger Ilm1 PF10311.9 ORX89167.1 - 0.57 9.8 2.8 0.53 9.9 0.3 1.8 1 1 1 2 2 2 0 Increased loss of mitochondrial DNA protein 1 PHD PF00628.29 ORX89167.1 - 1.6 8.7 12.7 0.27 11.2 8.0 2.1 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 ORX89167.1 - 3.8 7.2 14.5 0.52 10.0 8.7 2.3 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORX89167.1 - 5.2 7.0 14.2 0.35 10.8 8.3 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DUF953 PF06110.11 ORX89168.1 - 5.4e-23 80.9 0.1 6.1e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 ORX89168.1 - 0.027 14.2 0.3 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 Thioredoxin Pyridox_oxase_2 PF12766.7 ORX89169.1 - 4.2e-28 97.9 0.0 6.4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ORX89169.1 - 4.3e-10 39.7 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-H2C2_2 PF13465.6 ORX89170.1 - 4e-12 46.0 18.9 2.6e-06 27.6 1.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX89170.1 - 1.5e-11 44.0 26.2 0.0017 18.7 7.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORX89170.1 - 1.9e-10 40.5 17.2 0.00099 19.1 1.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORX89170.1 - 1.5e-09 37.9 23.8 0.0015 19.2 5.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX89170.1 - 4e-07 30.2 7.5 0.00056 20.1 1.6 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX89170.1 - 9.8e-05 22.6 5.1 9.8e-05 22.6 5.1 2.2 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 ORX89170.1 - 0.00056 20.2 13.1 0.017 15.5 0.8 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORX89170.1 - 0.0051 17.2 14.3 0.0065 16.9 4.7 2.9 2 1 1 3 3 2 1 C2HE / C2H2 / C2HC zinc-binding finger Rep_fac-A_C PF08646.10 ORX89170.1 - 0.13 12.0 1.6 8.5 6.1 1.6 2.2 1 1 0 1 1 1 0 Replication factor-A C terminal domain GAGA PF09237.11 ORX89170.1 - 0.14 12.0 1.7 0.35 10.7 0.8 2.0 1 1 1 2 2 2 0 GAGA factor Zn-ribbon_8 PF09723.10 ORX89170.1 - 0.41 10.8 5.9 0.81 9.9 0.3 3.0 3 0 0 3 3 3 0 Zinc ribbon domain zf_ZIC PF18366.1 ORX89170.1 - 0.79 9.9 6.4 5 7.3 0.3 3.1 2 1 1 3 3 3 0 Zic proteins zinc finger domain FOXP-CC PF16159.5 ORX89170.1 - 0.96 10.1 4.0 2.9 8.6 0.1 2.6 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 ORX89170.1 - 1.2 9.1 9.2 0.25 11.3 2.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORX89170.1 - 1.2 8.9 13.2 4.4 7.2 0.5 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORX89170.1 - 2.8 8.3 9.6 6.3 7.2 0.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 ORX89170.1 - 8.5 6.1 15.5 0.29 10.8 1.8 3.4 3 1 1 4 4 4 0 MYST family zinc finger domain BTB_2 PF02214.22 ORX89171.1 - 2.8e-15 56.4 0.0 6.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 ORX89171.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Xan_ur_permease PF00860.20 ORX89172.1 - 2.7e-84 283.1 42.2 3.3e-84 282.8 42.2 1.1 1 0 0 1 1 1 1 Permease family ALMT PF11744.8 ORX89172.1 - 0.43 9.4 4.1 0.7 8.6 4.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TB2_DP1_HVA22 PF03134.19 ORX89173.1 - 4.9e-16 58.4 6.9 1.2e-15 57.2 6.9 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3981 PF13139.6 ORX89173.1 - 0.061 13.7 1.1 0.061 13.7 1.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) CBP_BcsG PF11658.8 ORX89173.1 - 0.067 11.6 1.0 0.077 11.4 1.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG ECF_trnsprt PF12822.7 ORX89173.1 - 3.7 7.6 6.9 12 5.9 6.9 1.8 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Ribonuclease_T2 PF00445.18 ORX89174.1 - 1.1e-34 120.3 0.7 1.5e-34 119.9 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Amidohydro_1 PF01979.20 ORX89176.1 - 3.5e-73 246.9 1.7 5.2e-73 246.3 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORX89176.1 - 1.5e-56 189.9 2.6 3.5e-56 188.7 2.6 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 ORX89176.1 - 4.8e-39 132.7 0.2 1.1e-38 131.6 0.2 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 ORX89176.1 - 1.5e-38 130.7 0.0 2.9e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 ORX89176.1 - 6.3e-06 25.9 0.5 2.8e-05 23.8 0.0 2.2 2 1 0 3 3 3 1 Amidohydrolase family Glyoxalase PF00903.25 ORX89177.1 - 1.1e-07 32.1 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BAG PF02179.16 ORX89178.1 - 1.8e-16 60.3 0.8 3.1e-16 59.6 0.8 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 ORX89178.1 - 6.6e-10 38.6 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORX89178.1 - 6.6e-06 26.5 0.0 2.2e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain V-SNARE PF05008.15 ORX89178.1 - 0.0023 18.3 1.8 0.14 12.5 0.1 2.9 3 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus WD40 PF00400.32 ORX89179.1 - 7.1e-29 99.5 8.4 1.3e-05 25.9 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 ORX89179.1 - 3.6e-26 92.1 0.0 5.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin eIF2A PF08662.11 ORX89179.1 - 3.9e-09 36.7 0.0 0.0018 18.2 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORX89179.1 - 1.2e-08 35.2 0.0 0.019 15.2 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX89179.1 - 0.13 11.2 0.2 17 4.3 0.1 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sas10_Utp3 PF04000.15 ORX89180.1 - 1.6e-19 70.3 0.0 1.9e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Titin_Ig-rpts PF06582.12 ORX89180.1 - 0.068 13.1 0.2 6.7 6.7 0.0 2.5 2 1 0 2 2 2 0 Titin repeat MSC PF09402.10 ORX89181.1 - 4.9e-82 276.1 0.0 6.5e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORX89181.1 - 5.1e-13 48.5 1.6 6.9e-13 48.1 0.4 1.9 2 0 0 2 2 2 1 HeH/LEM domain SAP PF02037.27 ORX89181.1 - 0.026 14.3 0.5 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 SAP domain Toxin_19 PF08088.12 ORX89181.1 - 0.18 11.9 1.7 0.39 10.9 1.7 1.4 1 0 0 1 1 1 0 Conotoxin I-superfamily ABC_membrane PF00664.23 ORX89182.1 - 2.1e-55 188.3 3.0 2.7e-55 187.9 3.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORX89182.1 - 2.1e-34 119.0 0.0 5e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORX89182.1 - 0.00013 21.5 0.0 0.00091 18.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain KH_1 PF00013.29 ORX89182.1 - 0.0053 16.6 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 KH domain AAA_29 PF13555.6 ORX89182.1 - 0.0085 15.8 0.5 0.022 14.5 0.5 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORX89182.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 ORX89182.1 - 0.047 14.0 1.3 0.95 9.7 1.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX89182.1 - 0.13 12.6 0.2 0.37 11.2 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 ORX89182.1 - 0.73 10.1 3.2 0.79 10.0 0.2 2.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CutC PF03932.14 ORX89183.1 - 2.7e-75 252.3 0.0 3.6e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 CutC family Waikav_capsid_1 PF12264.8 ORX89183.1 - 0.071 12.6 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Waikavirus capsid protein 1 TIM PF00121.18 ORX89183.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Triosephosphate isomerase Nup160 PF11715.8 ORX89184.1 - 2e-42 145.6 0.0 6.5e-42 143.9 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TPR_2 PF07719.17 ORX89184.1 - 0.025 14.7 0.3 0.54 10.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Brix PF04427.18 ORX89185.1 - 3.7e-29 102.2 0.2 5.4e-29 101.7 0.2 1.2 1 0 0 1 1 1 1 Brix domain Involucrin2 PF06994.11 ORX89185.1 - 0.39 10.8 5.5 1.1 9.4 5.5 1.8 1 0 0 1 1 1 0 Involucrin NARP1 PF12569.8 ORX89186.1 - 2.1e-184 614.3 32.8 7.1e-184 612.5 23.4 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 ORX89186.1 - 5.6e-21 72.9 28.1 7.8e-05 22.5 0.3 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89186.1 - 6.7e-17 60.8 9.8 0.011 16.5 0.0 10.1 7 3 4 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89186.1 - 8.2e-17 61.5 21.0 0.0005 20.5 0.1 7.9 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORX89186.1 - 8.2e-16 56.8 22.5 0.00041 20.3 0.3 9.1 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89186.1 - 1.2e-15 57.8 2.1 0.2 12.3 0.0 7.4 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89186.1 - 3.6e-14 51.9 30.3 0.00056 19.6 1.3 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORX89186.1 - 2.4e-12 46.8 2.0 0.00017 21.7 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89186.1 - 4.5e-10 39.7 17.5 0.032 14.5 1.2 7.4 6 1 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX89186.1 - 1.8e-08 34.5 19.2 0.0011 19.2 0.4 5.7 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORX89186.1 - 3.9e-08 32.8 10.8 0.023 14.7 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89186.1 - 9.3e-08 31.6 15.1 0.0023 17.6 0.3 7.2 6 2 2 8 8 8 2 TPR repeat TPR_6 PF13174.6 ORX89186.1 - 2.5e-07 30.9 14.5 2.1 9.2 0.0 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORX89186.1 - 4.6e-05 22.8 8.5 0.00087 18.6 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX89186.1 - 0.00029 20.3 1.0 0.053 12.9 0.0 3.4 2 1 2 4 4 4 1 MalT-like TPR region TPR_3 PF07720.12 ORX89186.1 - 0.00063 19.7 6.7 0.024 14.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX89186.1 - 0.00078 19.2 3.8 13 5.8 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat VRP1 PF03538.14 ORX89186.1 - 0.00098 18.6 0.8 0.0024 17.3 0.8 1.6 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein TPR_17 PF13431.6 ORX89186.1 - 0.0014 18.9 13.5 0.42 11.1 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat BTAD PF03704.17 ORX89186.1 - 0.14 12.6 7.3 0.68 10.4 0.3 3.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 ORX89186.1 - 0.18 11.5 0.7 15 5.2 0.0 3.7 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF357 PF04010.13 ORX89186.1 - 0.72 10.0 2.8 12 6.1 0.0 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.6 ORX89186.1 - 1.1 9.4 19.9 2.3 8.3 0.1 6.0 6 1 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat MAPKK1_Int PF08923.10 ORX89187.1 - 1.2e-21 76.7 0.5 2.4e-20 72.5 0.5 2.0 1 1 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.17 ORX89187.1 - 0.054 13.3 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain TauD PF02668.16 ORX89188.1 - 4.8e-39 134.8 0.3 7.7e-39 134.1 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORX89188.1 - 1.3e-12 48.2 0.0 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORX89188.1 - 0.0046 16.1 0.0 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 CsiD PH PF00169.29 ORX89189.1 - 1.5e-08 35.0 3.2 0.0005 20.5 0.6 3.0 3 0 0 3 3 3 2 PH domain FERM_f0 PF16511.5 ORX89189.1 - 0.0017 18.6 0.1 0.0078 16.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM TFIID-31kDa PF02291.15 ORX89190.1 - 9.7e-52 174.2 0.0 1.4e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX89190.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 ORX89190.1 - 0.00015 22.2 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX89190.1 - 0.00067 20.0 0.1 0.001 19.4 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX89190.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID_30kDa PF03540.13 ORX89190.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.24 ORX89191.1 - 1.2e-21 77.4 0.1 1.5e-21 77.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORX89191.1 - 5.6e-07 29.7 0.2 9.9e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORX89191.1 - 0.0011 19.4 0.0 0.0019 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 ORX89191.1 - 0.017 15.1 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-W PF15510.6 ORX89191.1 - 0.04 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein Cytochrom_C PF00034.21 ORX89192.1 - 4.5e-12 46.9 0.1 6.9e-12 46.3 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORX89192.1 - 1.1e-08 35.3 2.7 9.3e-08 32.3 2.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORX89192.1 - 0.00038 20.2 0.6 0.0052 16.5 0.1 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 ORX89192.1 - 0.0099 16.5 0.0 0.011 16.4 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 ORX89192.1 - 0.18 11.4 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CFEM PF05730.11 ORX89193.1 - 0.58 10.3 13.3 1.9 8.6 13.3 1.8 1 1 0 1 1 1 0 CFEM domain Cyt-b5 PF00173.28 ORX89194.1 - 1e-13 51.2 0.1 1.2e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PPR_2 PF13041.6 ORX89195.1 - 2.4e-75 248.6 11.5 3.9e-12 46.2 0.2 15.5 10 3 7 17 17 17 12 PPR repeat family PPR PF01535.20 ORX89195.1 - 1.1e-53 175.8 21.2 2.1e-05 24.5 0.0 16.4 19 0 0 19 19 18 12 PPR repeat PPR_3 PF13812.6 ORX89195.1 - 1.5e-50 169.1 12.3 7.4e-08 32.4 0.0 13.6 9 3 5 14 14 14 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX89195.1 - 1.3e-39 133.6 11.7 2.5e-06 27.1 0.0 13.1 13 0 0 13 13 13 9 PPR repeat PPR_long PF17177.4 ORX89195.1 - 4.1e-26 91.7 9.5 0.0013 18.2 0.0 8.0 2 1 7 9 9 9 7 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 ORX89195.1 - 8.8e-05 22.9 0.1 22 5.7 0.0 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat RPM2 PF08579.11 ORX89195.1 - 9.4e-05 22.8 0.8 1.1 9.7 0.1 4.9 4 1 0 4 4 4 2 Mitochondrial ribonuclease P subunit (RPM2) Exog_C PF18026.1 ORX89195.1 - 0.0009 19.3 0.2 23 5.1 0.0 5.2 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain ECSIT PF06239.11 ORX89195.1 - 0.0023 17.1 0.9 5.3 6.1 0.1 4.3 4 2 0 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.6 ORX89195.1 - 0.0032 18.1 3.7 7 7.4 0.5 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX89195.1 - 0.0098 14.8 0.2 1.9 7.3 0.0 3.7 3 1 1 5 5 5 1 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 ORX89195.1 - 0.018 14.9 0.0 0.52 10.2 0.0 3.3 2 0 0 2 2 2 0 Mitochondrial ATPase expression BKACE PF05853.12 ORX89195.1 - 0.039 13.3 0.5 34 3.6 0.1 4.2 3 1 1 4 4 4 0 beta-keto acid cleavage enzyme ThiD2 PF17792.1 ORX89195.1 - 0.053 14.0 0.1 0.78 10.2 0.0 2.8 2 1 0 2 2 2 0 ThiD2 family Peptidase_C54 PF03416.19 ORX89196.1 - 5e-91 304.9 0.0 5.8e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 ORX89196.1 - 0.055 12.9 0.1 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 Peptidase family C78 Gpr1_Fun34_YaaH PF01184.19 ORX89197.1 - 3.2e-37 128.2 20.8 3.9e-37 127.9 20.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cyclin PF08613.11 ORX89198.1 - 3.1e-11 43.9 0.0 3.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX89198.1 - 9e-10 38.4 0.0 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Snf7 PF03357.21 ORX89199.1 - 4.3e-52 176.2 14.4 4.3e-52 176.2 14.4 1.8 2 0 0 2 2 2 1 Snf7 DUF2586 PF10758.9 ORX89199.1 - 0.031 13.5 1.4 0.035 13.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) DUF2344 PF10105.9 ORX89199.1 - 2.4 8.0 7.5 1.9 8.3 5.8 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Cyclin PF08613.11 ORX89200.1 - 3.4e-34 118.5 0.8 6.7e-34 117.6 0.7 1.5 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX89200.1 - 4.8e-06 26.3 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_C28 PF05408.11 ORX89200.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase DUF1298 PF06974.13 ORX89201.1 - 1.4e-23 83.5 0.0 2.2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 ORX89201.1 - 3.9e-19 69.5 0.0 2.9e-18 66.6 0.0 2.0 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 ORX89201.1 - 0.00075 18.3 0.0 0.012 14.4 0.0 2.0 2 0 0 2 2 2 1 Condensation domain DUF1871 PF08958.10 ORX89201.1 - 0.0027 18.0 0.0 0.62 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1871) Arrestin_N PF00339.29 ORX89204.1 - 2e-08 34.4 0.0 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX89204.1 - 2.2e-08 34.6 0.0 1.5e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORX89204.1 - 0.17 11.0 0.1 5.1 6.2 0.0 2.8 4 0 0 4 4 4 0 Rgp1 Cyclin PF08613.11 ORX89205.1 - 1.3e-11 45.2 0.0 1.9e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX89205.1 - 0.00083 19.1 0.0 0.0019 17.9 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF3383 PF11863.8 ORX89205.1 - 0.21 10.5 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Cyclin PF08613.11 ORX89206.1 - 6e-11 43.0 0.0 6e-11 43.0 0.0 2.3 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 ORX89206.1 - 0.11 12.3 0.3 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Cyclin, N-terminal domain IMS PF00817.20 ORX89207.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family PH_9 PF15410.6 ORX89208.1 - 7.5e-30 103.7 0.0 2.5e-29 102.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORX89208.1 - 3.1e-07 30.8 0.1 1.3e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 PH domain YCII PF03795.14 ORX89208.1 - 0.009 16.4 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 YCII-related domain Lzipper-MIP1 PF14389.6 ORX89208.1 - 1.6 9.1 7.7 0.16 12.3 0.6 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CsbD PF05532.12 ORX89209.1 - 0.00027 20.8 0.7 0.00061 19.6 0.7 1.5 1 0 0 1 1 1 1 CsbD-like MMR_HSR1 PF01926.23 ORX89210.1 - 2.2e-15 56.7 0.0 8.4e-14 51.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX89210.1 - 2.3e-08 34.1 0.2 0.00054 19.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORX89210.1 - 1.8e-06 27.6 0.2 6.1e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORX89210.1 - 0.00061 19.4 2.8 0.56 9.7 0.2 2.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORX89210.1 - 0.024 14.7 0.0 0.024 14.7 0.0 4.2 4 1 1 5 5 5 0 Dynamin family AIG1 PF04548.16 ORX89210.1 - 0.039 13.3 0.7 0.12 11.7 0.0 2.1 2 1 0 2 2 2 0 AIG1 family cobW PF02492.19 ORX89210.1 - 0.075 12.6 0.3 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Eaf7 PF07904.13 ORX89210.1 - 0.49 10.8 6.9 0.31 11.5 1.7 3.1 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Goodbye PF17109.5 ORX89210.1 - 4.3 7.8 12.7 11 6.4 0.7 3.4 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain RNA_pol_Rpc4 PF05132.14 ORX89210.1 - 10 6.6 11.0 25 5.3 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase III RPC4 DJ-1_PfpI PF01965.24 ORX89211.1 - 2.1e-08 34.2 0.0 8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX89211.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX89211.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX89212.1 - 1.7e-08 34.4 0.0 6.2e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX89212.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX89212.1 - 0.0037 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DUF1100 PF06500.11 ORX89213.1 - 3.1e-12 46.0 0.0 4.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 ORX89213.1 - 1e-07 32.8 0.0 6.2e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORX89213.1 - 3.1e-07 30.6 0.0 6.7e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ORX89213.1 - 1.1e-06 28.2 0.2 1.2e-05 24.7 0.2 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX89213.1 - 5e-06 26.3 0.2 2.9e-05 23.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX89213.1 - 1e-05 25.1 0.1 0.0001 21.9 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 ORX89213.1 - 4.2e-05 22.4 0.0 0.0037 16.0 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) UPF0227 PF05728.12 ORX89213.1 - 0.00028 20.9 0.0 0.00052 20.0 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 ORX89213.1 - 0.0082 15.7 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peripla_BP_6 PF13458.6 ORX89213.1 - 0.042 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Peptidase_M75 PF09375.10 ORX89213.1 - 0.055 12.9 1.1 0.13 11.7 1.1 1.6 2 0 0 2 2 2 0 Imelysin Abhydrolase_2 PF02230.16 ORX89213.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DJ-1_PfpI PF01965.24 ORX89214.1 - 2.1e-08 34.2 0.0 8e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX89214.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX89214.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain Glyco_hydro_16 PF00722.21 ORX89217.1 - 1e-16 60.9 0.4 1.5e-16 60.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 F-box-like PF12937.7 ORX89219.1 - 2.6e-12 46.4 1.7 5.9e-12 45.3 1.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORX89219.1 - 1.2e-06 28.7 1.0 0.2 12.2 0.0 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX89219.1 - 0.00029 21.0 0.8 2.3 9.1 0.0 4.3 3 0 0 3 3 3 1 Leucine Rich Repeat F-box PF00646.33 ORX89219.1 - 0.0012 18.7 0.5 0.0049 16.7 0.5 2.1 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORX89219.1 - 0.0013 18.6 1.6 1.3 9.3 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat NPL4 PF05021.15 ORX89219.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 NPL4 family Inhibitor_I68 PF10468.9 ORX89219.1 - 2.9 8.4 6.7 6.6 7.2 0.6 2.9 3 0 0 3 3 3 0 Carboxypeptidase inhibitor I68 DDT PF02791.17 ORX89220.1 - 7.5e-13 48.6 0.4 1.5e-12 47.6 0.4 1.6 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 ORX89220.1 - 6.4e-08 33.0 1.7 6.4e-08 33.0 1.7 3.5 2 2 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 ORX89220.1 - 6.2e-07 29.9 1.3 1.1e-06 29.0 0.1 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM1 PF15612.6 ORX89220.1 - 0.00039 19.9 0.2 0.00094 18.7 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 LUC7 PF03194.15 ORX89220.1 - 0.12 12.0 5.2 0.27 10.8 5.2 1.6 1 0 0 1 1 1 0 LUC7 N_terminus TcdB_N PF12918.7 ORX89220.1 - 0.46 10.8 2.9 2.2 8.6 0.6 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain WD40 PF00400.32 ORX89221.1 - 2.4e-30 104.1 16.4 4.8e-08 33.5 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89221.1 - 1.5e-11 44.5 0.1 0.49 10.7 0.1 5.3 1 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX89221.1 - 0.0012 17.9 0.1 0.31 10.0 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORX89221.1 - 0.015 14.7 0.0 1.3 8.3 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 ORX89221.1 - 0.046 12.4 0.4 0.53 8.9 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF3425 PF11905.8 ORX89221.1 - 0.054 13.5 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) CK_II_beta PF01214.18 ORX89222.1 - 4.5e-83 277.5 0.1 5.9e-83 277.1 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HAD PF12710.7 ORX89222.1 - 0.046 14.1 0.1 0.071 13.5 0.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sulfate_transp PF00916.20 ORX89223.1 - 1.3e-52 178.9 14.5 2.2e-52 178.1 14.5 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ORX89223.1 - 6.8e-15 54.9 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORX89223.1 - 2e-08 33.9 0.3 6.1e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 STAS domain Fungal_TACC PF12709.7 ORX89224.1 - 0.0017 18.7 6.4 0.088 13.3 3.9 2.7 2 0 0 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 ORX89224.1 - 0.46 10.5 2.9 1.3 9.1 2.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YscO PF07321.12 ORX89224.1 - 0.47 10.4 11.8 0.16 11.9 7.6 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Sigma70_ner PF04546.13 ORX89224.1 - 0.57 10.0 11.3 0.54 10.1 9.2 1.8 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF3450 PF11932.8 ORX89224.1 - 1.3 8.3 15.3 0.24 10.7 7.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HALZ PF02183.18 ORX89224.1 - 3.1 8.1 8.1 0.91 9.8 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 ORX89224.1 - 3.5 8.3 9.6 4 8.1 5.0 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Kunitz_BPTI PF00014.23 ORX89225.1 - 3e-32 110.6 34.0 5.6e-11 42.5 5.2 3.3 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain A_amylase_inhib PF01356.19 ORX89225.1 - 0.16 12.0 7.2 4.4 7.4 0.3 3.8 3 2 1 4 4 4 0 Alpha amylase inhibitor zf_CCCH_5 PF18384.1 ORX89225.1 - 5.9 7.1 8.9 23 5.2 0.0 4.0 4 0 0 4 4 4 0 Unkempt Zinc finger domain 1 (Znf1) Kunitz_BPTI PF00014.23 ORX89226.1 - 6.9e-25 87.0 16.0 3.9e-14 52.6 5.6 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain PAN_4 PF14295.6 ORX89226.1 - 0.035 14.0 2.7 5.5 7.0 0.2 3.2 2 1 1 3 3 3 0 PAN domain Choline_sulf_C PF12411.8 ORX89226.1 - 0.17 11.8 0.0 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal zf_CCCH_5 PF18384.1 ORX89226.1 - 0.7 10.1 7.5 3.6 7.8 0.5 2.8 2 1 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) Polysacc_deac_1 PF01522.21 ORX89227.1 - 1.3e-29 102.6 0.0 2e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORX89227.1 - 0.0017 18.1 0.2 0.004 16.8 0.1 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) FIVAR PF07554.13 ORX89227.1 - 2.1 9.2 8.5 0.16 12.7 2.7 2.2 2 0 0 2 2 2 0 FIVAR domain Aminotran_1_2 PF00155.21 ORX89228.1 - 4.6e-36 124.7 0.0 6.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX89228.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase RabGAP-TBC PF00566.18 ORX89230.1 - 2.4e-55 187.5 0.1 3.7e-55 186.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Thymidylate_kin PF02223.17 ORX89231.1 - 6.1e-46 156.4 0.0 7e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase ADK PF00406.22 ORX89231.1 - 0.0033 17.6 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORX89231.1 - 0.007 16.8 0.1 0.024 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORX89231.1 - 0.0082 16.4 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX89231.1 - 0.029 14.9 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 ORX89231.1 - 0.039 13.8 0.0 0.074 13.0 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf_UBZ PF18439.1 ORX89231.1 - 0.057 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger AAA_33 PF13671.6 ORX89231.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1748 PF08520.10 ORX89231.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) zf_C2H2_13 PF18508.1 ORX89231.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Zinc finger domain UPF0160 PF03690.13 ORX89232.1 - 1.9e-137 458.1 0.0 2.2e-137 457.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF3533 PF12051.8 ORX89233.1 - 2.8e-25 89.0 15.7 3.7e-25 88.7 15.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 ORX89233.1 - 2.7e-10 39.9 17.3 4.1e-10 39.3 17.3 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein Zn_clus PF00172.18 ORX89234.1 - 2.1e-14 53.3 11.2 3e-14 52.8 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L44 PF00935.19 ORX89234.1 - 6.6 7.3 10.9 0.49 10.9 6.3 1.5 1 1 1 2 2 2 0 Ribosomal protein L44 Fungal_trans PF04082.18 ORX89235.1 - 3.7e-15 55.7 0.3 7.6e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain COG5 PF10392.9 ORX89236.1 - 0.0033 17.6 5.8 0.024 14.8 0.9 2.6 2 0 0 2 2 2 2 Golgi transport complex subunit 5 DUF948 PF06103.11 ORX89236.1 - 1.1 9.5 4.9 37 4.7 0.0 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zn-ribbon_14 PF16503.5 ORX89237.1 - 2.7e-18 65.2 3.4 2.7e-18 65.2 3.4 2.8 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 ORX89237.1 - 7e-17 61.8 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 ORX89237.1 - 0.0042 15.9 0.0 0.0068 15.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.15 ORX89237.1 - 0.026 14.1 1.0 0.026 14.1 1.0 2.8 4 0 0 4 4 4 0 RecR protein IRF-2BP1_2 PF11261.8 ORX89237.1 - 0.14 11.8 1.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Sec1 PF00995.23 ORX89238.1 - 3.2e-78 264.4 11.7 4.1e-78 264.0 11.7 1.0 1 0 0 1 1 1 1 Sec1 family UPF0086 PF01868.16 ORX89239.1 - 6.6e-26 90.0 0.0 9.7e-26 89.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ank_2 PF12796.7 ORX89240.1 - 1.7e-08 35.0 0.1 6.7e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX89240.1 - 2e-07 31.4 0.0 0.02 15.4 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX89240.1 - 6e-05 23.1 0.0 0.0076 16.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORX89240.1 - 7.9e-05 22.9 0.0 0.023 15.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORX89240.1 - 0.00031 21.1 0.0 0.0075 16.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat FtsJ PF01728.19 ORX89241.1 - 4.6e-33 114.8 0.0 7.8e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase RabGAP-TBC PF00566.18 ORX89242.1 - 1.1e-58 198.5 0.3 3.6e-58 196.7 0.1 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain UPF0242 PF06785.11 ORX89242.1 - 1.5e-06 28.5 8.9 3.4e-06 27.3 8.9 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 ORX89242.1 - 0.00029 20.9 10.1 0.00029 20.9 10.1 3.6 3 1 1 5 5 3 1 Centrosomin N-terminal motif 1 HOOK PF05622.12 ORX89242.1 - 0.0014 16.9 19.8 0.0014 16.9 19.8 1.5 2 0 0 2 2 2 1 HOOK protein TolA_bind_tri PF16331.5 ORX89242.1 - 0.0043 17.1 2.9 0.0043 17.1 2.9 3.1 1 1 2 3 3 3 1 TolA binding protein trimerisation Fez1 PF06818.15 ORX89242.1 - 0.0069 16.9 19.4 0.014 15.8 19.4 1.5 1 0 0 1 1 1 1 Fez1 YabA PF06156.13 ORX89242.1 - 0.0084 16.7 14.1 0.14 12.8 5.4 2.8 1 1 1 2 2 2 2 Initiation control protein YabA KASH_CCD PF14662.6 ORX89242.1 - 0.07 13.0 20.3 1.3 8.8 20.3 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 ORX89242.1 - 0.19 11.9 26.2 1.9 8.7 7.6 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 ORX89242.1 - 0.23 11.6 26.7 0.14 12.2 2.9 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1640 PF07798.11 ORX89242.1 - 0.53 10.3 13.1 1.2 9.1 13.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CENP-F_leu_zip PF10473.9 ORX89242.1 - 0.56 10.2 24.9 1.2 9.1 24.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 ORX89242.1 - 0.85 9.8 17.3 4.6 7.4 2.0 3.7 1 1 3 4 4 4 0 bZIP transcription factor ERM PF00769.19 ORX89242.1 - 1.2 8.9 22.2 3.1 7.5 22.2 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.9 ORX89242.1 - 1.7 7.6 16.4 4.5 6.3 16.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 ORX89242.1 - 2.3 8.5 21.1 0.19 12.0 2.7 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper THOC7 PF05615.13 ORX89242.1 - 2.3 8.5 14.7 7 6.9 14.7 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 CtIP_N PF10482.9 ORX89242.1 - 2.6 8.1 17.4 21 5.2 8.0 3.1 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_TATA_bd PF12325.8 ORX89242.1 - 3.1 8.0 22.1 0.77 10.0 5.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 ORX89242.1 - 3.5 8.1 11.4 18 5.8 0.3 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 ORX89242.1 - 3.9 7.6 22.2 1.5 8.9 6.7 3.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 ORX89242.1 - 5.1 7.2 20.4 4.5 7.3 12.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cid2 PF09774.9 ORX89244.1 - 4.5e-20 72.7 3.4 3.8e-19 69.7 3.4 2.2 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Peptidase_S8 PF00082.22 ORX89245.1 - 6.6e-35 120.8 9.6 9.8e-35 120.2 9.6 1.3 1 1 0 1 1 1 1 Subtilase family Lipase_3 PF01764.25 ORX89246.1 - 2.9e-08 33.7 0.0 5.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX89246.1 - 0.17 11.4 0.3 19 4.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) UPF0227 PF05728.12 ORX89246.1 - 0.23 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) RGS PF00615.19 ORX89249.1 - 3.5e-12 46.6 2.9 5.7e-12 46.0 2.9 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX89249.1 - 0.0004 20.2 20.0 0.0032 17.2 20.0 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR MIP PF00230.20 ORX89251.1 - 1.8e-30 106.3 10.9 2.2e-30 106.1 10.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S8 PF00082.22 ORX89252.1 - 5.8e-33 114.4 20.4 1.1e-32 113.5 20.4 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX89252.1 - 0.00049 20.7 0.1 0.00098 19.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sec5 PF15469.6 ORX89253.1 - 1.2e-44 152.5 3.1 2.8e-44 151.2 3.1 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 ORX89253.1 - 6.6e-05 22.9 0.2 0.00018 21.5 0.2 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Vta1 PF04652.16 ORX89253.1 - 0.0087 16.0 0.0 0.035 14.1 0.0 2.0 1 0 0 1 1 1 1 Vta1 like DUF3158 PF11358.8 ORX89253.1 - 0.078 12.7 0.1 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) Med27 PF11571.8 ORX89253.1 - 0.41 11.0 2.2 0.91 9.9 0.0 2.8 3 0 0 3 3 3 0 Mediator complex subunit 27 Ribosomal_S11 PF00411.19 ORX89255.1 - 1.2e-25 90.0 0.0 2.3e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Haem_oxygenas_2 PF14518.6 ORX89255.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme Myb_DNA-binding PF00249.31 ORX89256.1 - 1.1e-14 54.3 0.3 2.1e-08 34.2 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX89256.1 - 6.7e-10 39.1 3.0 0.00092 19.4 0.1 3.3 3 1 0 3 3 3 2 Myb-like DNA-binding domain GPS2_interact PF15784.5 ORX89256.1 - 0.0024 18.3 7.4 0.058 13.8 0.3 3.4 2 0 0 2 2 2 2 G-protein pathway suppressor 2-interacting domain Myb_DNA-bind_7 PF15963.5 ORX89256.1 - 0.029 14.3 8.6 0.2 11.6 0.1 3.4 3 0 0 3 3 3 0 Myb DNA-binding like ER_lumen_recept PF00810.18 ORX89257.1 - 1e-52 178.8 15.4 1e-52 178.8 15.4 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORX89257.1 - 0.015 15.1 11.7 0.069 12.9 0.2 4.2 2 1 3 5 5 5 0 PQ loop repeat SLD3 PF08639.10 ORX89258.1 - 0.0017 17.2 2.1 0.0052 15.6 1.6 2.1 2 1 0 2 2 2 1 DNA replication regulator SLD3 Rab5ip PF07019.12 ORX89259.1 - 5.2 7.7 9.1 4.4 8.0 5.1 2.0 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) Rho_GDI PF02115.17 ORX89260.1 - 1.8e-65 220.4 0.4 2e-65 220.2 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF2748 PF10871.8 ORX89260.1 - 0.078 11.6 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) cNMP_binding PF00027.29 ORX89261.1 - 2.7e-44 149.1 0.1 2e-21 75.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ORX89261.1 - 3.5e-11 42.6 0.8 6.4e-11 41.7 0.8 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Mit_ribos_Mrp51 PF11709.8 ORX89262.1 - 6e-13 49.1 10.4 3.7e-11 43.2 2.5 3.6 2 1 1 3 3 3 2 Mitochondrial ribosomal protein subunit Allantoicase PF03561.15 ORX89262.1 - 0.22 11.5 1.1 0.47 10.4 0.3 1.9 2 1 0 2 2 2 0 Allantoicase repeat Pkinase PF00069.25 ORX89263.1 - 1e-63 215.2 0.0 3e-42 144.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89263.1 - 1.5e-31 109.7 0.1 2.1e-23 83.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 ORX89263.1 - 1.8e-15 57.1 0.1 3.5e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 ORX89263.1 - 2e-06 27.4 0.1 0.0011 18.3 0.0 2.9 3 0 0 3 3 3 2 Kinase-like PAS_4 PF08448.10 ORX89263.1 - 5.5e-05 23.4 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold APH PF01636.23 ORX89263.1 - 0.0014 18.6 0.1 0.0042 17.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX89263.1 - 0.0058 15.6 0.1 0.013 14.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Endonuclease_7 PF02945.15 ORX89263.1 - 0.024 14.6 3.2 0.054 13.4 3.2 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII Kdo PF06293.14 ORX89263.1 - 0.026 13.9 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 ORX89263.1 - 0.045 14.0 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 1 0 PAS domain RIO1 PF01163.22 ORX89263.1 - 0.047 13.3 0.0 0.32 10.6 0.0 2.3 2 1 0 3 3 3 0 RIO1 family Seadorna_VP7 PF07387.11 ORX89263.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 ORX89263.1 - 0.074 12.7 0.0 11 5.6 0.0 2.6 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1664 PF07889.12 ORX89264.1 - 0.076 13.0 2.6 0.15 12.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 ORX89264.1 - 0.098 11.9 4.9 0.2 10.9 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MRPL52 PF18699.1 ORX89264.1 - 0.24 11.6 3.3 0.76 10.0 2.3 2.4 2 0 0 2 2 2 0 Mitoribosomal protein mL52 ZapB PF06005.12 ORX89264.1 - 3.6 8.1 14.8 0.036 14.5 4.6 2.9 3 1 0 3 3 3 0 Cell division protein ZapB ACCA PF03255.14 ORX89264.1 - 6 6.7 5.9 1.3 8.9 2.2 1.8 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BCDHK_Adom3 PF10436.9 ORX89265.1 - 1.2e-37 129.3 0.5 1.9e-37 128.6 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX89265.1 - 4.8e-09 36.7 0.0 9.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORX89265.1 - 0.0036 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ORX89265.1 - 0.0046 16.9 0.1 0.44 10.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Serpin PF00079.20 ORX89266.1 - 4.8e-44 151.2 0.4 5.9e-44 150.9 0.4 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SfLAP PF11139.8 ORX89266.1 - 0.029 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein RNR_Alpha PF17975.1 ORX89267.1 - 1e-41 141.5 0.7 3.2e-41 139.9 0.2 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 ORX89267.1 - 3.2e-09 35.9 0.0 0.017 13.7 0.0 3.3 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Histidinol_dh PF00815.20 ORX89268.1 - 2.5e-163 543.9 0.7 4.7e-163 542.9 0.7 1.5 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 ORX89268.1 - 8.4e-25 86.4 0.1 1.7e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 ORX89268.1 - 3.9e-15 56.1 0.3 1.5e-14 54.2 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 ORX89268.1 - 0.021 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain CDC45 PF02724.14 ORX89269.1 - 1.2 7.4 12.1 1.2 7.3 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.6 ORX89270.1 - 1.8e-28 98.1 58.9 7.7e-08 32.0 0.8 5.6 1 1 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 ORX89270.1 - 1.2e-26 92.3 29.4 5.1e-07 29.9 2.4 5.6 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX89270.1 - 4.3e-20 71.9 6.1 8.1e-09 35.2 0.1 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 ORX89270.1 - 1.3e-06 28.0 32.9 1.2 9.4 0.2 8.5 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 ORX89270.1 - 0.00012 22.1 23.8 16 6.5 0.1 8.4 7 1 1 8 8 8 2 Leucine Rich Repeat Serpin PF00079.20 ORX89271.1 - 3.1e-76 257.1 0.1 3.8e-76 256.8 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SfLAP PF11139.8 ORX89271.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein NUDE_C PF04880.13 ORX89277.1 - 2e-05 25.2 22.9 2e-05 25.2 22.9 3.5 2 2 0 2 2 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.8 ORX89277.1 - 0.00024 18.8 20.3 0.00032 18.4 20.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AIP3 PF03915.13 ORX89277.1 - 0.00094 18.4 15.6 0.0055 15.8 16.5 1.7 1 1 1 2 2 2 1 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 ORX89277.1 - 0.0014 18.7 30.7 0.032 14.3 8.7 3.1 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 ORX89277.1 - 0.025 13.5 27.5 0.067 12.1 26.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2353 PF09789.9 ORX89277.1 - 0.032 13.6 25.6 0.0082 15.5 10.7 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) GAS PF13851.6 ORX89277.1 - 0.12 11.7 32.5 0.16 11.3 15.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4686 PF15742.5 ORX89277.1 - 0.13 11.4 32.0 0.25 10.4 22.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF4407 PF14362.6 ORX89277.1 - 0.22 10.8 12.5 1.5 8.1 12.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 ORX89277.1 - 0.32 11.1 30.8 2 8.5 20.0 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 ORX89277.1 - 0.52 10.7 24.3 10 6.4 8.2 3.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.9 ORX89277.1 - 0.52 10.3 37.1 4.2 7.4 24.0 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 ORX89277.1 - 0.8 9.8 26.7 0.74 9.9 7.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.11 ORX89277.1 - 1 10.0 21.3 0.43 11.2 5.3 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Atg14 PF10186.9 ORX89277.1 - 1.2 8.2 16.8 0.72 8.9 1.8 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 ORX89277.1 - 1.7 8.7 16.5 0.24 11.4 5.3 2.8 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 ORX89277.1 - 1.8 8.6 15.8 2.3 8.3 3.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 ORX89277.1 - 2.1 8.7 23.2 2.2 8.5 13.0 3.4 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) DUF4763 PF15960.5 ORX89277.1 - 2.1 7.6 20.4 96 2.2 19.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) DUF948 PF06103.11 ORX89277.1 - 2.2 8.6 12.0 3.1 8.1 0.7 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) TACC_C PF05010.14 ORX89277.1 - 2.2 8.0 27.2 44 3.8 25.8 2.7 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tup_N PF08581.10 ORX89277.1 - 3.8 7.9 30.3 1.7 9.0 5.1 3.7 2 1 2 4 4 3 0 Tup N-terminal RAWUL PF16207.5 ORX89277.1 - 4.2 8.1 5.4 36 5.1 0.3 2.6 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Prominin PF05478.11 ORX89277.1 - 4.2 5.2 14.5 6.3 4.6 13.9 1.6 1 1 0 1 1 1 0 Prominin DUF2203 PF09969.9 ORX89277.1 - 4.5 8.0 17.0 8.2 7.2 6.6 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) PI3K_P85_iSH2 PF16454.5 ORX89277.1 - 6.4 6.3 27.8 14 5.2 7.9 3.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Seryl_tRNA_N PF02403.22 ORX89277.1 - 7 6.9 22.3 3.7 7.8 9.7 3.8 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Zip PF02535.22 ORX89278.1 - 2.7e-17 63.0 5.2 3.4e-17 62.7 5.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CPP1-like PF11833.8 ORX89278.1 - 4.9 6.8 6.2 8.7 5.9 6.2 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Phage_holin_3_6 PF07332.11 ORX89278.1 - 7.4 6.6 16.0 1 9.4 3.9 2.4 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ras PF00071.22 ORX89279.1 - 2.3e-53 180.1 0.1 2.6e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89279.1 - 3e-36 124.3 0.0 4.3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89279.1 - 5.4e-16 58.5 0.0 6.3e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX89279.1 - 2.7e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX89279.1 - 3.1e-05 24.0 0.4 0.3 11.0 0.2 2.7 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORX89279.1 - 6.7e-05 22.5 0.5 0.00034 20.2 0.1 2.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX89279.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORX89279.1 - 0.00023 20.7 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORX89279.1 - 0.0024 18.3 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 ORX89279.1 - 0.0038 17.0 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORX89279.1 - 0.023 15.0 0.3 0.96 9.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORX89279.1 - 0.035 14.1 0.0 0.061 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) YwhD PF08741.10 ORX89279.1 - 0.036 13.7 0.1 0.054 13.2 0.1 1.3 1 1 0 1 1 1 0 YwhD family AAA_24 PF13479.6 ORX89279.1 - 0.037 13.7 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORX89279.1 - 0.086 12.9 0.1 11 6.0 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Raptor_N PF14538.6 ORX89279.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain NACHT PF05729.12 ORX89279.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 ORX89279.1 - 0.19 12.0 1.3 1 9.6 0.1 2.4 2 1 1 3 3 3 0 AAA domain zf-C2H2 PF00096.26 ORX89281.1 - 1.5e-14 53.5 9.8 5.3e-07 29.7 3.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89281.1 - 7.8e-12 45.1 9.4 2.4e-08 34.0 1.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89281.1 - 4.1e-08 33.4 8.5 0.0011 19.7 2.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX89281.1 - 2.6e-05 24.1 3.8 0.0051 16.8 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORX89281.1 - 0.0032 17.8 1.1 0.011 16.0 0.2 1.8 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORX89281.1 - 0.0039 17.4 0.5 0.085 13.2 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORX89281.1 - 0.019 14.7 5.9 0.42 10.4 1.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORX89281.1 - 0.023 15.1 1.1 0.026 15.0 0.2 1.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-TRAF PF02176.18 ORX89281.1 - 0.03 15.0 2.3 0.04 14.6 2.3 1.2 1 0 0 1 1 1 0 TRAF-type zinc finger CCAP PF11105.8 ORX89281.1 - 0.032 14.2 0.3 0.032 14.2 0.3 1.1 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a OSTMP1 PF09777.9 ORX89281.1 - 0.043 13.2 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf_C2H2_ZHX PF18387.1 ORX89281.1 - 0.31 10.7 3.1 0.68 9.6 1.2 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 ORX89281.1 - 0.56 10.3 5.7 1.8 8.6 1.5 2.2 2 0 0 2 2 2 0 BED zinc finger EF-hand_4 PF12763.7 ORX89283.1 - 3.3e-32 110.5 0.0 1.5e-17 63.4 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SH3_1 PF00018.28 ORX89283.1 - 1.6e-27 94.8 4.0 9e-14 50.8 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORX89283.1 - 1.2e-24 85.8 5.4 3e-12 46.2 0.2 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORX89283.1 - 5.8e-17 61.1 0.1 3.4e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_7 PF13499.6 ORX89283.1 - 6e-09 36.2 0.0 0.00026 21.4 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORX89283.1 - 7.1e-06 25.2 0.0 0.14 11.7 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 ORX89283.1 - 0.00046 19.9 0.0 3.3 7.9 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain Spore_III_AB PF09548.10 ORX89283.1 - 3.7 7.6 5.6 9.8 6.3 4.2 2.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Tup_N PF08581.10 ORX89283.1 - 3.9 7.9 11.1 5.8 7.3 1.1 3.1 2 0 0 2 2 2 0 Tup N-terminal DUF4570 PF15134.6 ORX89283.1 - 4.4 7.4 16.8 0.15 12.1 8.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF3573 PF12097.8 ORX89283.1 - 4.5 6.0 5.1 3.7 6.3 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) PMT_4TMC PF16192.5 ORX89284.1 - 1.3 8.6 8.9 3.8 7.0 8.6 2.0 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase F-box-like PF12937.7 ORX89285.1 - 5.1e-11 42.3 2.6 1.1e-10 41.3 2.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX89285.1 - 4.3e-09 36.0 0.5 7.5e-09 35.3 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORX89285.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 F-box GH43_C PF16369.5 ORX89285.1 - 0.046 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal lipocalin-like domain MHC_I_3 PF16497.5 ORX89285.1 - 0.063 12.7 0.2 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 MHC-I family domain Chitin_synth_2 PF03142.15 ORX89286.1 - 4.8e-253 840.6 0.2 6.9e-253 840.0 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX89286.1 - 4.4e-14 52.9 0.0 6.6e-13 49.1 0.0 2.6 3 1 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX89286.1 - 1.5e-12 47.9 5.8 5.9e-12 45.9 5.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX89286.1 - 0.01 15.3 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX89286.1 - 0.013 15.3 0.0 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sugar_tr PF00083.24 ORX89287.1 - 1.3e-56 192.4 18.7 3.5e-56 191.0 18.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX89287.1 - 1.4e-28 99.9 22.2 4.3e-28 98.2 21.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX89287.1 - 2.4e-07 30.4 3.8 5.3e-07 29.2 3.8 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX89287.1 - 0.00021 20.0 8.5 0.00021 20.0 8.5 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORX89287.1 - 0.1 12.1 4.7 0.066 12.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF417 Sugar_tr PF00083.24 ORX89288.1 - 3.7e-61 207.4 19.5 4.5e-61 207.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX89288.1 - 4.6e-28 98.1 25.8 1.6e-27 96.4 24.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX89288.1 - 6.8e-08 32.2 2.3 1.5e-07 31.0 2.3 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX89288.1 - 0.00037 19.2 10.1 0.00037 19.2 10.1 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORX89288.1 - 0.094 12.3 4.7 0.067 12.7 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF417 ATP-synt_C PF00137.21 ORX89289.1 - 3.1e-32 110.7 35.3 2.9e-21 75.6 14.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DBR1 PF05011.13 ORX89290.1 - 3.7e-40 137.6 0.5 3.7e-40 137.6 0.5 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ORX89290.1 - 3.8e-12 47.1 1.1 5.7e-12 46.6 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX89290.1 - 0.012 15.9 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORX89290.1 - 0.026 13.8 0.0 0.064 12.6 0.0 1.6 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Zn_clus PF00172.18 ORX89291.1 - 7e-05 22.9 17.0 7e-05 22.9 17.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 ORX89293.1 - 1.1e-20 73.1 0.0 1.2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX89293.1 - 7.1e-05 22.9 0.0 8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Cytochrom_B561 PF03188.16 ORX89295.1 - 1.1e-19 70.9 5.5 1.7e-19 70.3 5.5 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 HlyIII PF03006.20 ORX89295.1 - 0.2 11.3 10.2 0.16 11.7 2.4 2.2 1 1 1 2 2 2 0 Haemolysin-III related DPM3 PF08285.11 ORX89295.1 - 1.5 9.1 4.4 0.49 10.6 1.0 1.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TRAM_LAG1_CLN8 PF03798.16 ORX89297.1 - 2.8e-44 151.3 26.0 2.8e-44 151.3 26.0 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORX89297.1 - 2.9e-14 52.4 0.2 2.9e-14 52.4 0.2 2.5 3 0 0 3 3 3 1 TRAM1-like protein PDEase_II PF02112.15 ORX89298.1 - 2e-49 168.5 0.0 2.4e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 ORX89298.1 - 6.8e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Pkinase PF00069.25 ORX89299.1 - 5.1e-37 127.7 0.0 8.7e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89299.1 - 1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX89299.1 - 1e-07 32.1 0.4 4.6e-07 30.0 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX89299.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 ORX89299.1 - 0.0011 17.8 0.1 0.0017 17.2 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX89299.1 - 0.005 16.2 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORX89299.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 ORX89299.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORX89299.1 - 0.019 14.0 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PI3_PI4_kinase PF00454.27 ORX89299.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase CAF1C_H4-bd PF12265.8 ORX89300.1 - 5.1e-29 100.3 1.1 3.7e-28 97.6 0.3 2.7 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORX89300.1 - 6.7e-23 80.6 15.5 4.6e-05 24.1 0.5 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89300.1 - 0.0002 21.6 2.3 0.2 11.9 0.1 4.5 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX89300.1 - 0.024 13.6 0.0 2.3 7.1 0.0 2.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF-1a PF01176.19 ORX89300.1 - 0.1 12.4 0.2 15 5.5 0.2 2.5 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 WD40_like PF17005.5 ORX89300.1 - 0.17 11.2 0.0 0.6 9.4 0.0 2.0 2 1 0 2 2 2 0 WD40-like domain DUF3543 PF12063.8 ORX89301.1 - 4e-60 203.3 1.4 4e-60 203.3 1.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 ORX89301.1 - 2.5e-17 63.1 0.0 3.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89301.1 - 8.9e-07 28.5 0.0 1e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase MIT PF04212.18 ORX89301.1 - 0.0069 16.4 1.4 0.86 9.7 0.0 3.6 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain Lin-8 PF03353.15 ORX89302.1 - 0.43 10.1 4.5 0.54 9.8 4.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist KTI12 PF08433.10 ORX89304.1 - 1e-98 330.2 0.3 1.1e-98 330.0 0.3 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 ORX89304.1 - 1.8e-06 28.2 0.0 4.4e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX89304.1 - 0.017 15.6 0.0 0.071 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3656 PF12392.8 ORX89304.1 - 0.12 13.1 0.4 2.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Collagenase AAA_22 PF13401.6 ORX89304.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain MBOAT PF03062.19 ORX89305.1 - 5.2e-39 134.6 17.3 1.3e-34 120.1 12.0 3.3 2 1 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family GPI-anchored PF10342.9 ORX89307.1 - 8.9e-12 45.6 0.6 8.9e-12 45.6 0.6 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DAAD PF18752.1 ORX89307.1 - 0.01 15.7 0.8 0.013 15.4 0.8 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Raco_middle PF17651.1 ORX89307.1 - 0.12 12.1 1.9 0.27 10.9 0.7 1.9 1 1 1 2 2 2 0 RACo middle region DHHC PF01529.20 ORX89309.1 - 2.7e-27 95.5 12.2 4.2e-27 94.9 12.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Tubulin PF00091.25 ORX89312.1 - 2.6e-71 239.9 0.0 4.8e-71 239.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX89312.1 - 7.3e-42 142.5 0.1 1.2e-41 141.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX89312.1 - 3.8e-05 24.0 0.1 0.0001 22.6 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORX89312.1 - 0.00044 20.0 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORX89312.1 - 0.037 13.2 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Cyclin PF08613.11 ORX89313.1 - 1.5e-40 139.2 0.1 1.6e-40 139.1 0.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX89313.1 - 0.0014 18.4 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Porin_3 PF01459.22 ORX89314.1 - 4e-67 226.5 0.3 4.5e-67 226.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin AMP-binding PF00501.28 ORX89315.1 - 3.9e-90 302.5 0.0 4.9e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX89315.1 - 1.1e-17 64.8 0.1 2.2e-17 63.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ORX89315.1 - 0.0083 15.0 0.0 0.042 12.7 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter DUF3905 PF13045.6 ORX89315.1 - 0.086 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) RTX_C PF08339.10 ORX89315.1 - 0.21 11.7 0.0 3.2 7.8 0.0 2.3 1 1 1 2 2 2 0 RTX C-terminal domain HNH PF01844.23 ORX89316.1 - 0.0098 16.0 1.8 0.037 14.2 1.8 2.0 1 1 0 1 1 1 1 HNH endonuclease DUF968 PF06147.11 ORX89316.1 - 0.039 14.2 0.5 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF968) Tyrosinase PF00264.20 ORX89317.1 - 2.9e-34 119.3 11.0 4.6e-33 115.4 11.0 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF5347 PF17282.2 ORX89317.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5347) DUF4210 PF13915.6 ORX89318.1 - 5.7e-32 110.1 0.2 2.1e-31 108.3 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ORX89318.1 - 1.4e-24 86.0 0.1 3.5e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis ATG13 PF10033.9 ORX89318.1 - 0.00023 21.0 1.5 0.03 14.0 0.1 3.1 1 1 1 2 2 2 2 Autophagy-related protein 13 LPMO_10 PF03067.15 ORX89320.1 - 2.8e-05 24.9 0.3 9.7e-05 23.1 0.1 1.9 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX89320.1 - 0.0091 15.9 0.4 0.22 11.4 0.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.12 ORX89321.1 - 4.9e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX89321.1 - 5.2e-07 29.7 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX89321.1 - 0.0004 21.4 0.0 0.0008 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ins_P5_2-kin PF06090.12 ORX89322.1 - 1.6e-84 284.2 0.3 2.1e-84 283.8 0.3 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase AAA_33 PF13671.6 ORX89323.1 - 3.2e-17 63.0 0.3 1.1e-14 54.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX89323.1 - 0.00025 21.6 0.3 0.0091 16.5 0.3 2.4 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 ORX89323.1 - 0.0023 17.9 0.0 0.0064 16.4 0.0 1.8 2 0 0 2 2 1 1 NACHT domain G-alpha PF00503.20 ORX89323.1 - 0.0063 15.7 0.4 0.012 14.8 0.4 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_25 PF13481.6 ORX89323.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORX89323.1 - 0.01 16.3 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ORX89323.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ORX89323.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 ORX89323.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX89323.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 ORX89323.1 - 0.016 15.3 0.2 0.043 13.9 0.0 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_5 PF07728.14 ORX89323.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 ORX89323.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.6 ORX89323.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 ORX89323.1 - 0.024 15.0 0.1 0.04 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 ORX89323.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORX89323.1 - 0.036 14.5 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 ORX89323.1 - 0.041 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 ORX89323.1 - 0.05 13.1 1.3 0.18 11.2 0.1 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Septin PF00735.18 ORX89323.1 - 0.054 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.23 ORX89323.1 - 0.059 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4096 PF13340.6 ORX89323.1 - 0.066 13.4 0.8 0.27 11.5 0.2 2.3 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) 6PF2K PF01591.18 ORX89323.1 - 0.069 12.4 0.1 0.32 10.3 0.0 2.0 2 1 1 3 3 3 0 6-phosphofructo-2-kinase AAA_29 PF13555.6 ORX89323.1 - 0.07 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_PrkA PF08298.11 ORX89323.1 - 0.078 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Frankia_peptide PF14407.6 ORX89323.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. FtsK_SpoIIIE PF01580.18 ORX89323.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PPV_E1_C PF00519.17 ORX89323.1 - 0.094 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase CPT PF07931.12 ORX89323.1 - 0.095 12.5 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RsgA_GTPase PF03193.16 ORX89323.1 - 0.097 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 ORX89323.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORX89323.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORX89323.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 ORX89323.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 ORX89323.1 - 0.19 12.1 0.4 0.97 9.9 0.1 2.2 2 1 1 3 3 2 0 AAA domain DUF3267 PF11667.8 ORX89324.1 - 0.22 11.8 0.0 0.43 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative zincin peptidase Mito_carr PF00153.27 ORX89325.1 - 2.6e-70 232.4 1.8 3.2e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.21 ORX89326.1 - 7.1e-05 22.6 3.1 7.1e-05 22.6 3.1 2.0 1 1 0 2 2 2 1 PAP2 superfamily DUF2781 PF10914.8 ORX89326.1 - 0.077 13.4 6.3 0.54 10.7 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) Otopetrin PF03189.13 ORX89326.1 - 0.35 9.6 3.8 1.3 7.8 1.8 2.1 1 1 1 2 2 2 0 Otopetrin Glyco_hydro_20 PF00728.22 ORX89327.1 - 5.3e-93 312.2 0.9 6.4e-93 311.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORX89327.1 - 1.2e-13 51.9 0.0 2.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORX89327.1 - 0.11 13.3 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Adap_comp_sub PF00928.21 ORX89328.1 - 1e-90 303.7 0.0 1.3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORX89328.1 - 5.4e-10 39.4 1.0 8.7e-10 38.7 1.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 ORX89328.1 - 0.0035 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 ORX89328.1 - 0.053 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain PTR2 PF00854.21 ORX89329.1 - 2.8e-80 270.1 11.7 4.3e-80 269.5 11.7 1.2 1 0 0 1 1 1 1 POT family DUF3671 PF12420.8 ORX89329.1 - 9.6e-05 22.4 1.6 0.31 11.1 0.0 3.9 2 2 1 3 3 3 2 Protein of unknown function CENP-T_C PF15511.6 ORX89330.1 - 9.8e-06 25.7 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORX89330.1 - 0.0075 16.6 0.0 0.0089 16.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX89330.1 - 0.05 13.9 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX89330.1 - 0.052 13.6 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 ORX89330.1 - 0.074 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORX89330.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4743 PF15916.5 ORX89332.1 - 7.9e-20 71.0 0.1 1e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ORX89332.1 - 3.6e-09 36.8 0.0 6.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.6 ORX89338.1 - 1.6e-61 207.9 0.0 2.1e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX89338.1 - 2.8e-51 173.8 0.4 3.7e-51 173.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX89338.1 - 1.4e-13 51.2 0.1 2e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX89338.1 - 1.5e-06 27.9 0.8 1.3e-05 24.8 0.2 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX89338.1 - 3.4e-05 23.4 0.2 0.00075 19.0 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORX89338.1 - 0.0011 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORX89338.1 - 0.0027 16.9 0.1 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ELFV_dehydrog PF00208.21 ORX89338.1 - 0.0094 15.7 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DFP PF04127.15 ORX89338.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein tRNA-synt_1 PF00133.22 ORX89339.1 - 2.7e-227 755.8 0.0 6.2e-226 751.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORX89339.1 - 4.6e-36 124.1 0.8 1.2e-35 122.7 0.8 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORX89339.1 - 1.9e-16 59.8 0.0 2.4e-06 26.6 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORX89339.1 - 3.5e-09 36.4 11.9 6.5e-09 35.6 0.1 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 ORX89339.1 - 6.1e-06 26.4 0.4 6.1e-06 26.4 0.4 3.5 4 1 0 4 4 4 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 ORX89339.1 - 0.0033 16.8 0.0 0.12 11.7 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Cyclin_N PF00134.23 ORX89340.1 - 9.8e-14 51.2 1.0 1.8e-11 43.9 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 ORX89340.1 - 0.0048 17.2 0.1 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 ORX89340.1 - 0.037 14.1 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Spy1 PF11357.8 ORX89340.1 - 0.056 13.7 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 Cell cycle regulatory protein TRAPP PF04051.16 ORX89341.1 - 3.5e-39 133.8 0.0 4.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component His_Phos_2 PF00328.22 ORX89342.1 - 9.9e-89 298.3 0.1 1.2e-88 298.0 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ORX89342.1 - 1.5e-39 134.0 0.0 3.4e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ORX89342.1 - 4.3e-05 23.2 0.0 9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ORX89342.1 - 0.0019 18.3 0.1 0.0093 16.0 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain DHquinase_I PF01487.15 ORX89342.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Type I 3-dehydroquinase LRR_1 PF00560.33 ORX89343.1 - 0.0067 16.8 0.1 9.5 7.2 0.0 3.8 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.7 ORX89343.1 - 0.0073 16.7 0.9 18 5.9 0.0 3.7 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) B12D PF06522.11 ORX89344.1 - 0.062 13.1 0.1 0.075 12.8 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3269 PF11673.8 ORX89344.1 - 0.11 12.9 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) zf-C2H2 PF00096.26 ORX89345.1 - 2.6e-08 33.9 15.6 4.6e-05 23.7 1.2 2.6 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89345.1 - 5e-06 26.9 15.1 0.0004 21.0 0.5 2.7 2 1 1 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX89345.1 - 0.00057 19.8 0.7 0.00057 19.8 0.7 3.3 2 2 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX89345.1 - 0.00091 19.6 3.6 0.00091 19.6 3.6 3.1 3 1 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 ORX89345.1 - 0.0023 18.5 3.0 0.15 12.7 0.3 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX89345.1 - 0.041 14.2 4.3 0.43 10.9 4.3 2.0 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 ORX89345.1 - 0.065 13.6 6.4 2 8.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX89345.1 - 0.16 12.3 7.1 0.49 10.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORX89345.1 - 0.24 11.5 7.2 1.8 8.7 3.0 2.0 1 1 0 2 2 2 0 Aberrant zinc-finger Kelch_5 PF13854.6 ORX89346.1 - 1.3e-25 88.9 4.1 1.4e-05 24.9 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 ORX89346.1 - 1.7e-23 82.3 16.3 3e-08 33.8 0.2 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 ORX89346.1 - 1.9e-21 75.1 1.6 0.00014 21.7 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 ORX89346.1 - 1.1e-19 70.1 10.7 1.2e-05 25.2 0.1 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX89346.1 - 3e-18 65.4 12.0 5.5e-05 23.3 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORX89346.1 - 6.6e-16 57.6 1.4 0.00038 20.0 0.0 5.4 5 0 0 5 5 5 3 Kelch motif TMEM154 PF15102.6 ORX89346.1 - 0.03 14.2 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Glyco_hydro_9 PF00759.19 ORX89347.1 - 2.4e-123 412.6 17.5 2.7e-123 412.4 17.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF2399 PF09664.10 ORX89347.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) GATA PF00320.27 ORX89348.1 - 4.1e-11 42.3 6.7 1.1e-10 41.0 6.7 1.7 1 0 0 1 1 1 1 GATA zinc finger SMI1_KNR4 PF09346.10 ORX89351.1 - 0.00051 20.4 0.0 0.00085 19.7 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORX89351.1 - 0.015 15.7 0.0 0.079 13.4 0.0 2.1 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall DcuA_DcuB PF03605.14 ORX89352.1 - 0.028 13.3 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter E1-E2_ATPase PF00122.20 ORX89354.1 - 1e-47 162.0 0.5 1e-47 162.0 0.5 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 ORX89354.1 - 1.2e-31 108.9 3.2 1.2e-13 51.3 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 ORX89354.1 - 1.4e-30 107.2 0.5 8.5e-30 104.6 0.1 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX89354.1 - 0.00035 20.4 0.3 0.32 10.7 0.1 3.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX89354.1 - 0.0013 19.2 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORX89354.1 - 0.013 15.6 0.0 6.7 6.9 0.0 3.9 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase WAK PF08488.11 ORX89354.1 - 0.024 15.2 0.3 4 8.0 0.2 2.6 1 1 1 2 2 2 0 Wall-associated kinase DUF979 PF06166.12 ORX89354.1 - 0.037 13.2 2.9 0.05 12.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF979) Glyco_hydro_18 PF00704.28 ORX89354.1 - 0.078 12.7 1.5 5 6.7 0.4 2.7 2 1 1 3 3 3 0 Glycosyl hydrolases family 18 DUF2774 PF11242.8 ORX89354.1 - 0.096 12.9 0.2 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) CoA_binding_2 PF13380.6 ORX89354.1 - 0.098 13.2 0.1 0.78 10.2 0.1 2.4 2 0 0 2 2 2 0 CoA binding domain HTH_AsnC-type PF13404.6 ORX89354.1 - 0.19 11.6 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SLAC1 PF03595.17 ORX89355.1 - 1.4e-71 241.5 45.1 1.6e-71 241.3 45.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3343 PF11823.8 ORX89355.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Methyltransf_3 PF01596.17 ORX89356.1 - 1.7e-21 76.4 0.0 2.1e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX89356.1 - 2.5e-12 47.7 0.0 3.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX89356.1 - 0.012 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 ORX89356.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Cons_hypoth95 PF03602.15 ORX89356.1 - 0.047 13.3 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HAMP PF00672.25 ORX89357.1 - 3.3e-176 571.7 43.0 3.7e-08 33.6 0.0 23.3 22 1 0 22 22 22 21 HAMP domain HATPase_c PF02518.26 ORX89357.1 - 1.5e-29 102.7 0.1 6.6e-29 100.7 0.1 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box PF00505.19 ORX89357.1 - 3.1e-26 91.6 0.6 32 5.0 0.0 17.6 18 0 0 18 18 18 0 HMG (high mobility group) box APG17 PF04108.12 ORX89357.1 - 3.8e-26 92.1 13.9 0.0017 17.6 0.1 11.0 2 1 7 10 10 10 10 Autophagy protein Apg17 Response_reg PF00072.24 ORX89357.1 - 1.3e-24 86.5 0.3 6.1e-24 84.4 0.3 2.3 1 0 0 1 1 1 1 Response regulator receiver domain WXG100 PF06013.12 ORX89357.1 - 1e-21 76.9 49.3 0.97 9.7 0.1 20.3 19 2 3 23 23 22 7 Proteins of 100 residues with WXG DUF4279 PF14106.6 ORX89357.1 - 2.4e-19 69.6 0.6 8.9 6.6 0.0 17.9 21 0 0 21 21 19 0 Domain of unknown function (DUF4279) HisKA PF00512.25 ORX89357.1 - 4.2e-17 61.9 0.5 5.5e-16 58.3 0.5 3.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.17 ORX89357.1 - 1.4e-13 50.6 2.2 1.5e+02 2.4 0.0 16.0 17 0 0 17 17 17 0 Helix-turn-helix domain, rpiR family DUF1843 PF08898.10 ORX89357.1 - 6e-12 45.9 33.6 16 6.1 0.1 18.8 21 0 0 21 21 21 0 Domain of unknown function (DUF1843) ApoLp-III PF07464.11 ORX89357.1 - 2e-09 37.7 105.6 0.43 10.7 2.1 19.1 3 2 15 19 19 19 13 Apolipophorin-III precursor (apoLp-III) CENP-F_leu_zip PF10473.9 ORX89357.1 - 4.5e-08 33.2 66.2 12 5.9 0.0 20.5 23 0 0 23 23 23 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SpoIIID PF12116.8 ORX89357.1 - 3.2e-06 27.2 41.1 55 4.0 0.0 18.3 19 0 0 19 19 19 0 Stage III sporulation protein D Baculo_PEP_C PF04513.12 ORX89357.1 - 3.4e-06 27.1 158.5 0.044 13.8 2.1 20.1 5 2 9 18 18 18 7 Baculovirus polyhedron envelope protein, PEP, C terminus GatB_Yqey PF02637.18 ORX89357.1 - 1.3e-05 25.2 70.8 10 6.0 0.2 19.0 12 4 3 20 20 20 0 GatB domain DUF1759 PF03564.15 ORX89357.1 - 3.2e-05 23.9 32.3 36 4.3 0.0 16.3 20 0 0 20 20 20 0 Protein of unknown function (DUF1759) DUF5132 PF17195.4 ORX89357.1 - 0.00088 19.3 10.4 38 4.5 0.1 13.2 17 0 0 17 17 15 0 Protein of unknown function (DUF5132) Allene_ox_cyc PF06351.11 ORX89357.1 - 0.041 13.6 0.0 0.21 11.3 0.0 2.2 1 0 0 1 1 1 0 Allene oxide cyclase Fib_alpha PF08702.10 ORX89357.1 - 0.046 13.9 76.7 9.6 6.4 0.1 19.0 21 1 1 22 22 22 0 Fibrinogen alpha/beta chain family DUF5344 PF17279.2 ORX89357.1 - 0.73 10.4 56.0 14 6.3 0.1 16.6 19 0 0 19 19 16 0 Family of unknown function (DUF5344) OspD PF03207.13 ORX89357.1 - 1.7 8.0 124.3 0.94 8.8 0.7 18.8 16 4 0 19 19 18 0 Borrelia outer surface protein D (OspD) Abhydrolase_8 PF06259.12 ORX89357.1 - 2.2 7.9 128.6 3.2 7.4 0.5 19.7 18 2 1 20 20 20 0 Alpha/beta hydrolase VBS PF08913.10 ORX89357.1 - 2.4 8.6 87.2 25 5.3 0.2 19.1 19 1 1 20 20 20 0 Vinculin Binding Site LEA_2 PF03168.13 ORX89358.1 - 2.3e-05 24.9 0.0 3.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 ORX89358.1 - 0.013 14.8 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Exo_endo_phos PF03372.23 ORX89359.1 - 8.6e-17 61.4 0.1 1.5e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 ORX89359.1 - 6.4e-10 39.0 5.3 2.7e-09 37.0 5.3 2.2 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 ORX89359.1 - 1.4e-06 28.2 0.0 2.5e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase CRAL_TRIO PF00650.20 ORX89360.1 - 3.9e-34 117.7 0.1 5.3e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX89360.1 - 3.7e-10 39.8 0.0 8.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORX89360.1 - 0.024 14.8 0.1 0.067 13.3 0.0 1.7 2 1 0 2 2 2 0 Divergent CRAL/TRIO domain Aha1_N PF09229.11 ORX89361.1 - 2.6e-40 137.8 2.0 6e-40 136.6 2.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORX89361.1 - 5.6e-16 58.9 1.2 1e-15 58.0 0.5 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein 7tm_1 PF00001.21 ORX89362.1 - 1.3e-05 24.7 6.1 1.3e-05 24.7 6.1 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Shisa PF13908.6 ORX89362.1 - 0.13 12.5 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Methyltransf_2 PF00891.18 ORX89363.1 - 1.4e-31 109.4 0.0 2.2e-31 108.8 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORX89363.1 - 4.1e-07 29.9 0.0 7.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 ORX89363.1 - 0.0012 18.7 0.1 0.017 15.0 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX89363.1 - 0.01 15.6 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89363.1 - 0.014 16.1 0.1 6.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORX89363.1 - 0.025 15.3 0.1 1.2 9.9 0.0 3.3 3 1 0 3 3 3 0 Methyltransferase domain FtsJ PF01728.19 ORX89363.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 ORX89363.1 - 0.058 14.0 0.1 0.72 10.5 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain DprA_WH PF17782.1 ORX89363.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 DprA winged helix domain Bin3 PF06859.12 ORX89363.1 - 0.078 13.6 0.3 0.75 10.5 0.0 2.5 3 0 0 3 3 3 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_2 PF00891.18 ORX89364.1 - 1.4e-18 67.0 0.0 2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORX89364.1 - 9.3e-12 44.8 0.0 3e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_33 PF10017.9 ORX89364.1 - 0.061 12.5 0.1 5.4 6.1 0.0 2.4 1 1 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent FeoC PF09012.10 ORX89364.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator Methyltransf_2 PF00891.18 ORX89365.1 - 1.5e-34 119.2 0.0 2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORX89365.1 - 3e-07 30.3 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_31 PF13847.6 ORX89365.1 - 0.00041 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX89365.1 - 0.00062 19.6 0.1 0.015 15.1 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 ORX89365.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORX89365.1 - 0.0026 18.4 0.0 0.026 15.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89365.1 - 0.0027 18.4 0.0 0.0062 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORX89365.1 - 0.037 14.1 0.0 0.088 12.9 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase DprA_WH PF17782.1 ORX89365.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 DprA winged helix domain Methyltransf_11 PF08241.12 ORX89365.1 - 0.06 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 ORX89366.1 - 6.9e-35 120.2 0.0 8.6e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ORX89366.1 - 4.2e-07 29.9 0.0 1.1e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_31 PF13847.6 ORX89366.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX89366.1 - 0.0012 18.8 0.1 0.036 13.9 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX89366.1 - 0.0016 19.1 0.0 0.026 15.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89366.1 - 0.0019 18.9 0.0 0.0062 17.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 ORX89366.1 - 0.0034 16.9 0.0 0.0085 15.6 0.0 1.7 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 ORX89366.1 - 0.026 14.6 0.0 0.064 13.4 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 ORX89366.1 - 0.037 14.7 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DprA_WH PF17782.1 ORX89366.1 - 0.04 14.0 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 DprA winged helix domain HATPase_c PF02518.26 ORX89367.1 - 8.2e-26 90.7 0.2 1.8e-25 89.6 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX89367.1 - 2.4e-19 69.6 0.1 7.1e-19 68.0 0.1 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORX89367.1 - 2.4e-15 56.3 0.3 5.3e-15 55.2 0.3 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 ORX89367.1 - 2.4e-15 56.3 0.0 5.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 ORX89367.1 - 4.8e-12 46.6 0.1 6.7e-11 42.9 0.0 2.6 2 1 0 2 2 2 1 GAF domain PAS_2 PF08446.11 ORX89367.1 - 2.1e-09 38.0 0.0 1.2e-08 35.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold Pox_P4B PF03292.14 ORX89369.1 - 0.051 11.8 0.0 0.055 11.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein Diphthamide_syn PF01866.17 ORX89374.1 - 7.1e-120 400.0 0.0 8.6e-120 399.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ubiquitin_4 PF18036.1 ORX89376.1 - 1.3e-21 76.4 0.2 1.7e-21 76.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain DUF4888 PF16229.5 ORX89376.1 - 0.0029 17.6 0.1 0.0034 17.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4888) HgmA PF04209.13 ORX89377.1 - 1.8e-215 715.5 0.2 2.1e-215 715.3 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase eIF_4EBP PF05456.11 ORX89378.1 - 2.8e-31 107.8 6.8 4.3e-31 107.2 6.8 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PEMT PF04191.13 ORX89379.1 - 2.8e-17 63.0 15.0 5.6e-10 39.6 2.2 3.7 3 1 0 3 3 3 2 Phospholipid methyltransferase HMG_box PF00505.19 ORX89380.1 - 2.6e-15 56.6 0.1 4.9e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX89380.1 - 3.1e-06 27.7 0.0 7.9e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 HMG-box domain CAP PF00188.26 ORX89381.1 - 2.6e-18 67.1 0.1 3.4e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX89382.1 - 2.6e-18 67.1 0.1 3.4e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family bZIP_1 PF00170.21 ORX89384.1 - 0.0038 17.3 14.8 0.0057 16.7 3.3 2.6 1 1 1 2 2 2 2 bZIP transcription factor GIT_CC PF16559.5 ORX89384.1 - 1.4 8.8 6.4 5.9 6.8 6.4 2.1 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 ORX89384.1 - 5.5 7.0 10.4 9 6.4 9.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 ORX89384.1 - 7.1 7.2 13.9 2.4 8.7 9.4 2.5 2 1 0 2 2 2 0 Cell division protein ZapB Exo_endo_phos PF03372.23 ORX89385.1 - 1.2e-17 64.3 1.1 2.8e-17 63.0 1.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HhH-GPD PF00730.25 ORX89386.1 - 2.4e-14 53.7 0.0 6e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4434 PF14488.6 ORX89386.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) FHA PF00498.26 ORX89388.1 - 7.5e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORX89388.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain F_bP_aldolase PF01116.20 ORX89389.1 - 7.1e-92 307.8 0.0 8e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.16 ORX89390.1 - 2.6e-37 128.6 32.8 3.6e-37 128.1 32.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Tyrosinase PF00264.20 ORX89391.1 - 6.5e-34 118.2 9.8 1.1e-32 114.2 9.8 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Redoxin PF08534.10 ORX89392.1 - 1.2e-20 73.7 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORX89392.1 - 2.1e-05 24.4 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family WRKY PF03106.15 ORX89393.1 - 7.7e-08 32.5 1.4 1.2e-07 31.8 1.4 1.3 1 0 0 1 1 1 1 WRKY DNA -binding domain Pkinase PF00069.25 ORX89395.1 - 2.4e-48 164.8 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89395.1 - 7.8e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX89395.1 - 6e-05 22.5 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORX89395.1 - 0.0029 17.6 0.0 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX89395.1 - 0.038 12.9 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RNA12 PF10443.9 ORX89396.1 - 0.2 10.3 0.1 0.32 9.7 0.1 1.3 1 0 0 1 1 1 0 RNA12 protein Ras PF00071.22 ORX89397.1 - 9e-63 210.7 0.2 1.1e-62 210.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89397.1 - 1.1e-35 122.5 0.1 1.6e-35 121.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89397.1 - 6.4e-13 48.5 0.1 8.1e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX89397.1 - 4.5e-08 33.2 0.1 8.3e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX89397.1 - 0.00037 20.4 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORX89397.1 - 0.00039 20.0 0.2 0.0021 17.6 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORX89397.1 - 0.00046 20.5 0.0 0.0048 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 ORX89397.1 - 0.0009 18.7 0.1 0.0015 17.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORX89397.1 - 0.0068 16.8 0.3 0.016 15.6 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 ORX89397.1 - 0.0079 15.9 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORX89397.1 - 0.011 16.3 0.1 0.017 15.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 ORX89397.1 - 0.045 13.2 0.0 0.084 12.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ORX89397.1 - 0.047 13.2 0.1 0.083 12.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B GDP_Man_Dehyd PF16363.5 ORX89397.1 - 0.05 13.0 0.1 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AAA_7 PF12775.7 ORX89397.1 - 0.05 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORX89397.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain MgpC PF05220.12 ORX89397.1 - 0.088 12.1 0.1 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 MgpC protein precursor TniB PF05621.11 ORX89397.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_21 PF13304.6 ORX89397.1 - 0.12 12.2 1.0 0.32 10.8 0.5 1.8 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Mcp5_PH PF12814.7 ORX89398.1 - 2.5e-35 121.3 2.0 2.5e-35 121.3 2.0 1.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology GRDP-like PF07173.12 ORX89398.1 - 1.7 9.3 5.1 4.8 7.8 5.1 1.7 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like DIL PF01843.19 ORX89399.1 - 2.2e-20 72.9 3.7 5.7e-20 71.5 3.7 1.7 1 0 0 1 1 1 1 DIL domain Ank_5 PF13857.6 ORX89399.1 - 2.1e-14 53.4 0.2 8.1e-08 32.4 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX89399.1 - 9.1e-12 45.4 0.0 1e-10 42.0 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX89399.1 - 1.8e-10 40.8 0.7 0.00013 22.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORX89399.1 - 2.7e-06 27.8 0.2 3.7e-05 24.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX89399.1 - 1.2e-05 25.3 0.7 0.059 13.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Myticin-prepro PF10690.9 ORX89401.1 - 0.0094 16.2 0.3 0.015 15.6 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Myticin-prepro PF10690.9 ORX89405.1 - 0.0041 17.3 0.4 0.0065 16.7 0.4 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel ABC_membrane PF00664.23 ORX89406.1 - 1.2e-121 405.6 33.2 2.8e-61 207.6 11.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX89406.1 - 1.4e-71 239.3 0.1 6e-35 120.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX89406.1 - 5.3e-18 65.3 1.8 1.4e-05 24.6 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX89406.1 - 1.1e-09 38.9 1.2 0.00085 19.7 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 ORX89406.1 - 1.2e-07 30.9 0.4 0.0012 17.8 0.0 2.9 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORX89406.1 - 2.8e-07 30.2 0.7 0.0025 17.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX89406.1 - 6e-07 29.8 0.3 0.1 12.9 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 ORX89406.1 - 6.2e-07 29.9 0.8 0.081 13.3 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORX89406.1 - 1.5e-06 28.2 0.1 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 ORX89406.1 - 1.7e-06 28.1 0.2 0.15 11.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORX89406.1 - 5.1e-06 26.3 0.4 0.18 11.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORX89406.1 - 5.1e-06 26.5 0.0 0.15 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ORX89406.1 - 1.9e-05 24.6 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain APS_kinase PF01583.20 ORX89406.1 - 8.8e-05 22.4 0.0 0.56 10.1 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Rad17 PF03215.15 ORX89406.1 - 0.00015 21.8 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 ORX89406.1 - 0.00018 22.0 0.0 0.2 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORX89406.1 - 0.00039 20.0 0.0 0.66 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX89406.1 - 0.0006 20.0 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORX89406.1 - 0.00086 18.6 0.0 0.37 10.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 ORX89406.1 - 0.0017 17.9 0.0 0.32 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 ORX89406.1 - 0.0021 18.6 0.1 0.54 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 ORX89406.1 - 0.0031 16.8 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit SbcCD_C PF13558.6 ORX89406.1 - 0.0043 17.3 2.0 2.3 8.5 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ORX89406.1 - 0.01 15.6 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX89406.1 - 0.011 16.2 0.0 8.6 6.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Cytidylate_kin PF02224.18 ORX89406.1 - 0.011 15.5 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 ORX89406.1 - 0.022 15.0 0.0 4.2 7.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF1942 PF09167.11 ORX89406.1 - 0.026 14.5 0.1 0.088 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) ATP_bind_1 PF03029.17 ORX89406.1 - 0.029 14.1 0.1 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 ORX89406.1 - 0.042 14.3 0.0 16 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain PKHD_C PF18331.1 ORX89406.1 - 0.045 13.8 0.3 0.13 12.3 0.3 1.8 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain PRK PF00485.18 ORX89406.1 - 0.047 13.4 0.0 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 ORX89406.1 - 0.082 12.1 0.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORX89406.1 - 0.1 11.7 0.1 6.4 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 ORX89406.1 - 0.13 12.3 0.0 6.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 ORX89406.1 - 0.17 11.8 0.1 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 ORX89406.1 - 0.3 10.8 3.2 1.7 8.4 0.0 3.0 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF3671 PF12420.8 ORX89406.1 - 7.9 6.6 7.0 1.1 9.4 1.7 2.4 2 0 0 2 2 1 0 Protein of unknown function GST_C_3 PF14497.6 ORX89407.1 - 3e-19 69.1 0.2 4.4e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX89407.1 - 2.3e-08 34.1 0.1 3.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX89407.1 - 4.5e-07 29.8 0.0 1.2e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX89407.1 - 3.1e-05 24.3 0.0 9.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 ORX89407.1 - 0.00011 22.7 0.0 0.00022 21.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORX89407.1 - 0.00082 19.1 0.1 0.0021 17.8 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX89407.1 - 0.0015 18.8 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX89407.1 - 0.077 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LIM PF00412.22 ORX89408.1 - 2.6e-25 88.4 18.1 7.8e-13 48.4 5.6 2.2 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.6 ORX89408.1 - 0.15 12.0 6.0 0.39 10.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-FPG_IleRS PF06827.14 ORX89408.1 - 0.29 11.1 0.0 0.29 11.1 0.0 5.1 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 ORX89408.1 - 0.45 10.1 14.6 7.9 6.2 0.0 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ORX89408.1 - 2.5 8.3 16.3 3.1 8.0 0.6 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_12 PF11331.8 ORX89408.1 - 6.7 6.6 15.3 2.8 7.8 3.0 3.8 4 0 0 4 4 4 0 Probable zinc-ribbon domain Med13_C PF06333.12 ORX89408.1 - 9.9 5.3 11.9 20 4.3 11.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain ADH_zinc_N_2 PF13602.6 ORX89409.1 - 0.0085 17.1 0.0 0.015 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyridox_ox_2 PF12900.7 ORX89410.1 - 2.7e-29 102.0 0.0 1.8e-28 99.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Steroid_dh PF02544.16 ORX89411.1 - 5.2e-21 75.2 0.9 8e-21 74.6 0.9 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ribosomal_S8e PF01201.22 ORX89412.1 - 1.2e-49 168.1 4.8 2.8e-49 166.8 4.8 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e VIR_N PF15912.5 ORX89412.1 - 9.7 5.7 6.6 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Methyltransf_PK PF05891.12 ORX89416.1 - 1.3e-84 283.1 0.1 1.6e-84 282.8 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORX89416.1 - 2.1e-12 47.5 0.0 3.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX89416.1 - 2.6e-11 44.0 0.0 3.9e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89416.1 - 5.9e-07 30.1 0.0 8.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX89416.1 - 6.8e-06 26.0 0.0 3e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX89416.1 - 0.0071 16.1 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORX89416.1 - 0.03 13.6 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 ORX89416.1 - 0.058 12.7 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 ORX89416.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Arg_decarbox_C PF17944.1 ORX89416.1 - 0.15 12.7 0.0 6.2 7.5 0.1 2.9 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension YjeF_N PF03853.15 ORX89417.1 - 7.3e-36 123.6 0.0 9.7e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PEX11 PF05648.14 ORX89418.1 - 9.5e-49 165.8 0.8 1.1e-48 165.6 0.8 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) WD40 PF00400.32 ORX89419.1 - 2.7e-65 214.7 18.5 1.7e-11 44.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89419.1 - 4.6e-27 94.2 1.9 0.00014 22.1 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX89419.1 - 6.3e-16 58.1 4.5 0.0061 15.3 0.0 5.4 1 1 5 6 6 6 5 Nucleoporin Nup120/160 eIF2A PF08662.11 ORX89419.1 - 1.3e-14 54.5 0.5 2.3e-07 30.9 0.0 3.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX89419.1 - 4.1e-07 29.6 0.1 0.00071 19.0 0.0 3.6 1 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 ORX89419.1 - 2.8e-06 26.5 6.0 0.22 10.4 0.0 4.7 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 ORX89419.1 - 9.5e-06 24.8 4.1 0.25 10.2 0.0 4.8 1 1 5 6 6 6 3 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 ORX89419.1 - 0.00017 20.1 0.1 0.0022 16.4 0.0 2.2 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 ORX89419.1 - 0.0037 16.4 0.1 0.21 10.6 0.0 2.8 1 1 2 3 3 3 2 VID27 C-terminal WD40-like domain PD40 PF07676.12 ORX89419.1 - 0.0091 15.9 1.8 1.2 9.2 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 ORX89419.1 - 0.014 14.5 0.1 16 4.4 0.0 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1513) IKI3 PF04762.12 ORX89419.1 - 0.062 11.3 0.1 0.12 10.4 0.1 1.4 1 0 0 1 1 1 0 IKI3 family Hira PF07569.11 ORX89419.1 - 0.13 11.9 3.2 16 5.1 0.0 4.1 3 1 2 5 5 5 0 TUP1-like enhancer of split Cyclin_N PF00134.23 ORX89420.1 - 1.8e-14 53.6 0.1 2.1e-14 53.4 0.1 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX89420.1 - 3.3e-09 37.3 0.1 3.6e-09 37.2 0.1 1.0 1 0 0 1 1 1 1 Cyclin zf-C2H2 PF00096.26 ORX89421.1 - 3.3e-20 71.3 31.6 2.2e-05 24.6 0.4 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89421.1 - 5.7e-20 70.8 29.2 2.7e-06 27.5 1.8 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89421.1 - 8.1e-12 44.9 28.6 0.013 16.3 3.0 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX89421.1 - 4.2e-07 30.5 10.5 0.023 15.3 0.4 3.7 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX89421.1 - 3.9e-05 23.8 10.7 0.35 11.2 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX89421.1 - 0.002 18.4 15.8 0.18 12.1 2.6 2.6 1 1 2 3 3 3 3 C2H2-type zinc ribbon BolA PF01722.18 ORX89421.1 - 0.0052 17.0 3.3 1.9 8.8 2.3 3.1 2 1 0 2 2 2 1 BolA-like protein zf-met PF12874.7 ORX89421.1 - 0.043 14.2 16.5 6.1 7.4 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORX89421.1 - 0.23 12.2 12.6 0.39 11.4 1.9 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORX89421.1 - 2.6 8.2 10.1 1.7 8.8 0.4 3.4 1 1 1 3 3 3 0 Aberrant zinc-finger zf-LYAR PF08790.11 ORX89421.1 - 8.8 6.3 8.7 20 5.2 0.2 3.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF21 PF01595.20 ORX89422.1 - 1.5e-33 116.0 0.0 2.7e-33 115.1 0.0 1.4 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORX89422.1 - 3.8e-09 36.9 0.1 0.0027 18.1 0.0 2.6 2 1 0 2 2 2 2 CBS domain FAD_binding_4 PF01565.23 ORX89423.1 - 1.8e-12 47.1 0.0 2.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain LssY_C PF14067.6 ORX89423.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 LssY C-terminus BPL_N PF09825.9 ORX89424.1 - 6.3e-112 374.4 0.0 8e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 ORX89424.1 - 5.4e-24 84.6 0.0 9.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 ORX89424.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DJ-1_PfpI PF01965.24 ORX89424.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glyco_hydro_42M PF08532.10 ORX89424.1 - 0.047 13.2 0.1 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain WD40 PF00400.32 ORX89425.1 - 1.2e-44 149.4 27.4 7.1e-07 29.8 0.5 8.3 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORX89425.1 - 2.2e-12 46.6 0.1 4.5e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX89425.1 - 5.7e-08 32.4 0.3 1.4e-07 31.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORX89425.1 - 1.5e-06 28.4 2.2 3.3 8.1 0.1 5.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 ORX89425.1 - 5.7e-06 26.2 0.0 2.1e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 F-box Nup160 PF11715.8 ORX89425.1 - 3.9e-05 22.5 8.2 3 6.4 0.3 5.7 5 1 1 6 6 6 4 Nucleoporin Nup120/160 PQQ PF01011.21 ORX89425.1 - 0.018 15.0 0.5 1.5 8.9 0.2 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat DUF4597 PF15366.6 ORX89425.1 - 0.26 11.1 1.5 1.4 8.7 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Acetyltransf_1 PF00583.25 ORX89426.1 - 2.4e-12 47.1 0.0 3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX89426.1 - 1.5e-07 31.4 0.0 4.5e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX89426.1 - 0.00045 20.6 0.0 0.00066 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX89426.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX89426.1 - 0.0038 17.3 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX89426.1 - 0.0078 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase NmrA PF05368.13 ORX89427.1 - 1.8e-55 188.0 0.5 2.5e-55 187.6 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX89427.1 - 4.3e-12 46.3 0.2 5.8e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORX89427.1 - 0.00019 20.5 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORX89427.1 - 0.00027 21.2 0.0 0.00093 19.5 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORX89427.1 - 0.002 17.6 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF5397 PF17375.2 ORX89427.1 - 0.059 13.1 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5397) AdoHcyase_NAD PF00670.21 ORX89427.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DXP_reductoisom PF02670.16 ORX89427.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SIP1 PF04938.12 ORX89428.1 - 1.9e-47 161.8 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SCAN PF02023.17 ORX89428.1 - 0.41 10.5 3.3 13 5.7 0.2 3.0 1 1 2 3 3 3 0 SCAN domain ACT_7 PF13840.6 ORX89429.1 - 1.1e-26 92.4 0.0 3.7e-16 58.7 0.0 2.6 3 0 0 3 3 3 2 ACT domain Castor1_N PF18700.1 ORX89429.1 - 2.3e-11 43.3 0.4 6.2e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT PF01842.25 ORX89429.1 - 0.00013 21.7 0.0 0.22 11.3 0.0 2.8 2 1 0 2 2 2 2 ACT domain Ammonium_transp PF00909.21 ORX89430.1 - 1.8e-118 395.7 25.4 2.1e-118 395.5 25.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family LPMO_10 PF03067.15 ORX89433.1 - 9.9e-05 23.1 0.2 0.0012 19.6 0.0 2.7 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX89433.1 - 0.0062 16.5 0.0 0.084 12.8 0.0 2.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 61 SpuA_C PF18033.1 ORX89434.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 SpuA C-terminal zf-MYND PF01753.18 ORX89435.1 - 1.3e-07 31.5 15.5 2.7e-07 30.6 15.5 1.6 1 0 0 1 1 1 1 MYND finger DUF167 PF02594.16 ORX89436.1 - 1.7e-25 88.9 0.6 2.2e-25 88.6 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 LAL_C2 PF18603.1 ORX89436.1 - 0.031 14.4 0.3 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Syntaxin PF00804.25 ORX89437.1 - 7e-29 100.9 16.9 7e-29 100.9 16.9 1.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 ORX89437.1 - 5.5e-12 45.5 1.1 1.3e-11 44.3 1.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 ORX89437.1 - 7.6e-05 23.0 5.5 7.6e-05 23.0 5.5 2.5 2 1 0 2 2 2 1 Syntaxin-like protein Vps51 PF08700.11 ORX89437.1 - 0.0035 17.4 6.7 0.13 12.4 1.4 2.7 2 0 0 2 2 2 2 Vps51/Vps67 FF PF01846.19 ORX89437.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 FF domain MFS_Mycoplasma PF07672.13 ORX89437.1 - 0.1 11.9 0.6 0.17 11.1 0.6 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF3198 PF11433.8 ORX89437.1 - 0.11 12.5 2.0 0.32 10.9 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) LMBR1 PF04791.16 ORX89437.1 - 0.2 10.5 8.0 0.25 10.2 8.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MCPsignal PF00015.21 ORX89437.1 - 0.28 11.0 9.6 0.032 14.0 3.4 2.4 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Orf78 PF06024.12 ORX89437.1 - 1.8 8.9 5.7 0.25 11.6 0.5 2.2 2 1 0 2 2 2 0 Orf78 (ac78) EMP24_GP25L PF01105.24 ORX89437.1 - 5.3 7.0 9.4 0.65 9.9 4.4 2.2 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4988 PF16378.5 ORX89437.1 - 9.3 5.9 8.3 4.1 7.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function Ribosomal_S17e PF00833.18 ORX89438.1 - 5e-65 216.9 0.2 5.8e-65 216.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 WD40 PF00400.32 ORX89439.1 - 2.1e-23 82.2 7.1 0.00011 22.8 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89439.1 - 1.6e-08 34.8 8.2 0.00036 20.8 0.4 5.0 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 ORX89439.1 - 0.00094 17.7 0.2 0.0013 17.2 0.2 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Glyco_hyd_101C PF17451.2 ORX89439.1 - 0.028 14.7 2.4 6.6 7.1 0.3 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Sec1 PF00995.23 ORX89440.1 - 3.5e-129 432.6 0.0 4e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AMP-binding PF00501.28 ORX89441.1 - 2.9e-106 355.6 0.0 4e-106 355.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme p53-inducible11 PF14936.6 ORX89441.1 - 0.12 12.4 0.5 6.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 AMP-binding_C PF13193.6 ORX89441.1 - 0.13 13.2 0.0 0.46 11.5 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pex14_N PF04695.13 ORX89442.1 - 2.3e-20 73.8 0.0 4.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Syntaphilin PF15290.6 ORX89442.1 - 0.024 14.3 0.1 0.024 14.3 0.1 1.5 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp DUF5546 PF17700.1 ORX89442.1 - 0.057 13.8 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5546) Glyoxalase PF00903.25 ORX89443.1 - 1.2e-19 70.8 0.0 1.3e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORX89443.1 - 2e-12 47.4 0.0 2.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORX89443.1 - 4.7e-05 23.3 0.1 0.00022 21.2 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ORX89443.1 - 0.0034 17.5 0.0 0.0049 17.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ORX89443.1 - 0.0045 17.7 0.0 0.0066 17.2 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain zf-CCCH PF00642.24 ORX89444.1 - 1.2e-12 47.4 16.3 4.5e-07 29.6 2.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORX89444.1 - 1.3e-05 24.9 0.0 2.9e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 ORX89444.1 - 0.0015 18.7 6.9 0.14 12.3 1.0 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 ORX89444.1 - 0.013 15.5 2.9 0.013 15.5 2.9 2.7 2 0 0 2 2 2 0 Zinc finger domain Torus PF16131.5 ORX89444.1 - 0.17 12.6 0.2 0.17 12.6 0.2 2.9 2 1 1 3 3 3 0 Torus domain TPR_1 PF00515.28 ORX89446.1 - 1.9e-55 182.5 34.0 9.3e-08 31.6 0.0 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORX89446.1 - 1.6e-47 155.8 25.5 1.6e-06 27.8 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORX89446.1 - 6e-35 116.5 23.2 1.9e-06 27.6 0.0 10.5 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89446.1 - 3.8e-25 88.3 9.3 1.5e-05 25.6 0.0 6.4 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORX89446.1 - 6.5e-25 85.7 24.6 0.0014 18.9 0.1 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89446.1 - 7.7e-25 85.5 14.3 0.00025 21.6 0.0 9.0 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89446.1 - 3.6e-24 85.1 13.9 3.3e-05 24.3 0.3 6.4 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89446.1 - 8.8e-23 80.4 21.6 0.00012 22.3 2.9 7.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORX89446.1 - 1.5e-21 75.5 19.9 0.0026 18.3 0.0 9.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORX89446.1 - 8.8e-20 69.2 12.1 0.015 15.2 0.3 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89446.1 - 6.9e-18 64.1 32.6 3.3e-06 26.7 0.8 8.7 5 3 4 9 9 9 4 TPR repeat TPR_9 PF13371.6 ORX89446.1 - 3.3e-16 59.2 8.7 0.0058 16.8 0.2 5.9 2 2 5 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX89446.1 - 7.5e-11 42.1 13.6 1.3e-06 28.6 4.0 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORX89446.1 - 1.3e-06 27.9 13.7 1.1 8.3 0.2 5.6 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.9 ORX89446.1 - 2.2e-06 27.5 6.9 0.46 10.2 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 ORX89446.1 - 0.0023 17.7 3.8 0.27 10.9 1.5 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Tcf25 PF04910.14 ORX89446.1 - 0.018 14.1 0.2 0.18 10.9 0.0 2.4 2 1 0 2 2 2 0 Transcriptional repressor TCF25 ChAPs PF09295.10 ORX89446.1 - 0.037 13.0 2.8 5.7 5.8 0.1 3.2 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 ORX89446.1 - 0.045 14.1 4.9 1.7 9.0 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 ORX89446.1 - 0.058 12.8 17.2 5.4 6.4 0.2 4.9 2 2 1 3 3 3 0 Soluble NSF attachment protein, SNAP DUF627 PF04781.12 ORX89446.1 - 0.18 11.8 1.2 23 5.1 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Coatomer_WDAD PF04053.14 ORX89446.1 - 0.37 9.8 2.3 1.7 7.6 0.0 2.7 3 0 0 3 3 3 0 Coatomer WD associated region BTAD PF03704.17 ORX89446.1 - 2.1 8.8 8.7 40 4.6 0.1 3.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 ORX89446.1 - 3.1 7.9 26.6 4.2 7.5 2.3 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TOM20_plant PF06552.12 ORX89446.1 - 4.1 7.1 5.2 52 3.5 0.1 4.0 4 1 0 5 5 4 0 Plant specific mitochondrial import receptor subunit TOM20 RRM_1 PF00076.22 ORX89447.1 - 6.1e-18 64.4 0.0 9.6e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORX89447.1 - 2.1e-08 34.6 4.6 2.1e-08 34.6 4.6 2.5 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 ORX89447.1 - 0.00025 20.8 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif UPF0061 PF02696.14 ORX89448.1 - 1.4e-145 485.7 0.0 1.6e-145 485.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family EF-hand_11 PF08976.11 ORX89448.1 - 0.073 13.9 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Methyltr_RsmB-F PF01189.17 ORX89449.1 - 6.8e-80 267.4 0.0 9.9e-80 266.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 ORX89449.1 - 3e-09 37.3 0.0 1.4e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 ORX89449.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 ORX89449.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2431 PF10354.9 ORX89449.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Noc2 PF03715.13 ORX89450.1 - 9.9e-128 425.6 0.6 9.9e-128 425.6 0.6 2.2 2 0 0 2 2 2 1 Noc2p family WD40 PF00400.32 ORX89451.1 - 3e-23 81.7 10.4 2.8e-07 31.1 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89451.1 - 5.5e-07 29.8 0.0 1.1 9.6 0.0 5.3 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX89451.1 - 0.033 12.8 0.2 10 4.6 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PDZ_5 PF17817.1 ORX89452.1 - 0.024 14.9 0.2 0.037 14.3 0.2 1.3 1 0 0 1 1 1 0 PDZ domain Fumble PF03630.14 ORX89453.1 - 2.2e-114 382.1 0.9 2.5e-114 381.9 0.9 1.0 1 0 0 1 1 1 1 Fumble RRM_1 PF00076.22 ORX89454.1 - 3.7e-80 263.7 2.8 4.7e-20 71.2 0.3 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORX89454.1 - 2.5e-29 101.3 0.8 1.3e-28 98.9 1.0 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORX89454.1 - 8.8e-13 47.9 0.6 0.0092 15.6 0.0 4.3 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX89454.1 - 0.00014 21.7 0.0 0.0073 16.1 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX89454.1 - 0.00076 19.6 1.0 12 6.1 0.0 4.8 3 1 0 4 4 4 1 RNA recognition motif DUF4523 PF15023.6 ORX89454.1 - 0.0014 18.5 0.0 16 5.3 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 ORX89454.1 - 0.0018 18.3 0.8 9.7 6.3 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 ORX89454.1 - 0.019 14.6 0.4 15 5.3 0.0 3.7 4 1 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 ORX89454.1 - 0.025 14.8 0.1 0.61 10.3 0.0 2.8 3 0 0 3 3 3 0 RRM-like domain YflT PF11181.8 ORX89454.1 - 0.033 14.7 5.3 0.73 10.4 2.2 3.3 4 0 0 4 4 3 0 Heat induced stress protein YflT RRM_3 PF08777.11 ORX89454.1 - 0.038 14.0 7.8 2.4 8.3 2.5 3.4 3 1 1 4 4 4 0 RNA binding motif OB_RNB PF08206.11 ORX89454.1 - 0.067 12.9 2.5 23 4.8 0.1 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Caudo_TAP PF02413.17 ORX89454.1 - 0.25 11.5 2.4 1.4 9.1 0.2 2.8 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK Pol_alpha_B_N PF08418.10 ORX89454.1 - 0.3 11.0 3.0 7.2 6.5 0.1 3.1 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Glyco_transf_54 PF04666.13 ORX89455.1 - 6.8e-05 21.9 0.7 0.00066 18.6 0.1 2.2 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Sec3_C PF09763.9 ORX89456.1 - 8.4e-33 113.7 0.7 9.1e-33 113.6 0.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 FANCI_S3 PF14677.6 ORX89456.1 - 0.0044 16.8 2.2 0.023 14.4 0.8 1.9 1 1 1 2 2 2 1 FANCI solenoid 3 LepB_GAP_N PF18172.1 ORX89456.1 - 0.061 13.2 0.2 1.6 8.6 0.1 2.0 1 1 1 2 2 2 0 LepB GAP domain N-terminal subdomain US30 PF17624.2 ORX89456.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function dDENN PF03455.19 ORX89456.1 - 0.41 10.7 2.8 1.1 9.3 2.8 1.8 1 1 0 1 1 1 0 dDENN domain Sec3_C PF09763.9 ORX89457.1 - 3.8e-50 171.1 20.2 2.9e-38 131.7 6.2 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec3 Vps52 PF04129.12 ORX89457.1 - 0.00087 18.1 0.9 0.00087 18.1 0.9 1.7 2 0 0 2 2 2 1 Vps52 / Sac2 family EntA_Immun PF08951.10 ORX89457.1 - 0.27 11.6 2.9 0.49 10.8 1.3 2.3 2 0 0 2 2 2 0 Enterocin A Immunity Pkinase PF00069.25 ORX89458.1 - 9.5e-69 231.7 0.0 1.2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89458.1 - 4.7e-31 108.0 0.0 6.3e-31 107.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX89458.1 - 0.0021 17.1 0.0 0.0044 16.0 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORX89458.1 - 0.033 13.8 0.3 2.2 7.9 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORX89458.1 - 0.062 13.2 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX89458.1 - 0.11 11.8 0.1 0.25 10.6 0.1 1.5 1 1 0 1 1 1 0 Kinase-like zf-CHY PF05495.12 ORX89459.1 - 1.7e-13 50.8 12.9 3.6e-13 49.8 12.9 1.5 1 1 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 ORX89459.1 - 0.0084 16.2 4.3 0.0084 16.2 4.3 2.7 2 1 1 3 3 3 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 ORX89459.1 - 0.013 15.4 8.2 1.8 8.6 0.0 3.4 2 1 1 3 3 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 ORX89459.1 - 0.2 11.7 9.9 17 5.5 0.0 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.12 ORX89459.1 - 0.33 11.2 11.0 46 4.3 0.2 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain DUF4379 PF14311.6 ORX89459.1 - 2 8.9 9.3 0.2 12.0 0.8 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-DNL PF05180.12 ORX89459.1 - 2.9 7.9 9.2 12 5.9 3.2 3.1 2 1 0 2 2 2 0 DNL zinc finger HypA PF01155.19 ORX89459.1 - 5 7.2 10.6 28 4.8 10.6 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DEAD PF00270.29 ORX89460.1 - 4.8e-45 153.5 0.8 4.8e-45 153.5 0.8 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX89460.1 - 9.1e-33 112.9 0.5 5.3e-32 110.5 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX89460.1 - 2.6e-07 30.8 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX89460.1 - 0.00023 21.5 0.5 0.0037 17.6 0.3 2.3 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 ORX89460.1 - 0.00048 19.5 0.1 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 ORX89460.1 - 0.00068 19.4 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 ORX89460.1 - 0.02 14.8 0.1 0.068 13.1 0.1 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 ORX89460.1 - 0.04 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 ORX89460.1 - 0.051 12.9 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) IL17R_D_N PF16742.5 ORX89460.1 - 0.08 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 ORX89460.1 - 0.29 11.4 1.1 1.3 9.3 0.2 2.5 2 1 0 2 2 2 0 AAA domain Ribosomal_L14 PF00238.19 ORX89461.1 - 2.2e-35 121.4 0.1 2.6e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L11_N PF03946.14 ORX89462.1 - 1.5e-24 85.6 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORX89462.1 - 3e-17 62.9 0.2 6.2e-17 61.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain DUF4745 PF15923.5 ORX89463.1 - 0.033 14.2 0.8 0.057 13.4 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4745) CENP-X PF09415.10 ORX89463.1 - 0.097 13.0 0.3 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pkinase PF00069.25 ORX89464.1 - 3.7e-16 59.3 0.0 6.5e-08 32.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89464.1 - 3.8e-09 36.2 0.0 0.00032 20.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORX89464.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX89464.1 - 0.00016 20.6 0.0 0.0002 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 ORX89464.1 - 0.0061 16.2 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Fer2_3 PF13085.6 ORX89464.1 - 0.073 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF775 PF05603.12 ORX89465.1 - 5e-56 189.4 0.5 6.4e-56 189.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) zf-C2H2 PF00096.26 ORX89466.1 - 1.1e-11 44.5 11.1 2.8e-06 27.5 1.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89466.1 - 5.5e-09 36.1 8.4 0.00019 22.0 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX89466.1 - 1e-06 28.9 14.1 1.7e-06 28.1 3.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX89466.1 - 2e-05 24.5 3.8 9.9e-05 22.2 0.3 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX89466.1 - 0.0013 18.9 1.1 0.0041 17.4 0.3 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX89466.1 - 0.0025 18.2 2.1 0.0093 16.3 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORX89466.1 - 0.018 15.6 0.3 0.11 13.1 0.1 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain HECT PF00632.25 ORX89467.1 - 1.9e-96 323.2 0.0 3.6e-96 322.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORX89467.1 - 3.7e-34 116.5 19.1 9.3e-12 44.8 1.5 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 ORX89467.1 - 2.2e-11 44.0 0.0 7.2e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 ORX89468.1 - 1.4e-25 90.2 0.0 1.5e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89468.1 - 9e-12 44.8 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX89468.1 - 1.1e-08 34.3 0.1 1.4e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX89468.1 - 0.0021 18.0 0.0 0.03 14.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX89468.1 - 0.043 13.1 0.0 0.18 11.1 0.0 1.8 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 ORX89468.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 ORX89469.1 - 5.1e-15 55.2 40.0 5.1e-15 55.2 40.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pho88 PF10032.9 ORX89470.1 - 5.4e-60 201.8 0.2 6.4e-60 201.5 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ribosomal_L7Ae PF01248.26 ORX89471.1 - 6.6e-28 96.3 4.0 8.4e-28 96.0 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Tyrosinase PF00264.20 ORX89472.1 - 3.3e-35 122.4 2.4 2.2e-34 119.7 2.4 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase zf-LITAF-like PF10601.9 ORX89473.1 - 5.8e-19 68.1 2.8 7.7e-19 67.7 2.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DZR PF12773.7 ORX89473.1 - 0.0078 16.2 4.4 0.35 10.9 0.9 2.3 1 1 1 2 2 2 2 Double zinc ribbon zf_Rg PF17915.1 ORX89473.1 - 0.12 11.8 0.5 0.12 11.8 0.5 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger RGS PF00615.19 ORX89474.1 - 5.5e-15 55.7 2.8 8.5e-15 55.1 2.8 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORX89474.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Suf PF05843.14 ORX89475.1 - 3.2e-88 296.5 0.0 9.1e-87 291.8 0.0 2.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORX89475.1 - 2.2e-07 31.1 1.0 0.00014 22.4 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORX89475.1 - 3.2e-05 23.7 1.8 0.0033 17.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89475.1 - 0.0023 17.7 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89475.1 - 0.0037 17.7 0.6 0.085 13.4 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89475.1 - 0.02 15.5 1.4 2.3 9.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NADH_B2 PF14813.6 ORX89475.1 - 0.059 13.2 0.0 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 TPR_8 PF13181.6 ORX89475.1 - 0.066 13.4 3.4 0.5 10.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89475.1 - 0.07 12.8 2.0 1.2 8.9 0.0 3.2 2 1 1 3 3 3 0 TPR repeat LSM PF01423.22 ORX89475.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 LSM domain RGS PF00615.19 ORX89475.1 - 0.12 12.6 0.4 2.7 8.3 0.1 2.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain TPR_7 PF13176.6 ORX89475.1 - 0.13 12.4 0.5 7.4 6.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORX89475.1 - 0.19 12.2 0.6 2.8 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89475.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.3 4 1 1 5 5 4 0 Tetratricopeptide repeat Glucan_synthase PF02364.15 ORX89476.1 - 0 1212.5 0.1 0 1212.5 0.1 1.7 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORX89476.1 - 2.9e-36 124.7 1.0 1.2e-35 122.7 1.0 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DEAD PF00270.29 ORX89477.1 - 5e-45 153.4 0.8 5e-45 153.4 0.8 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX89477.1 - 9.5e-33 112.9 0.5 5.4e-32 110.4 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX89477.1 - 2.7e-07 30.8 0.0 4.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX89477.1 - 0.00024 21.4 0.5 0.0038 17.6 0.3 2.3 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 ORX89477.1 - 0.0005 19.5 0.1 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 ORX89477.1 - 0.0007 19.4 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 ORX89477.1 - 0.021 14.8 0.1 0.07 13.1 0.1 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 ORX89477.1 - 0.041 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 ORX89477.1 - 0.052 12.8 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) IL17R_D_N PF16742.5 ORX89477.1 - 0.081 13.0 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 ORX89477.1 - 0.3 11.4 1.1 1.3 9.2 0.2 2.5 2 1 0 2 2 2 0 AAA domain R3H PF01424.22 ORX89478.1 - 1.2e-13 50.8 0.3 1.6e-13 50.4 0.3 1.2 1 0 0 1 1 1 1 R3H domain MAT1 PF06391.13 ORX89479.1 - 9.5e-51 172.5 24.9 1.2e-50 172.2 24.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 ORX89479.1 - 3.7e-22 78.0 8.3 7.9e-22 76.9 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX89479.1 - 2.8e-06 27.2 9.3 3.3e-05 23.7 9.7 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORX89479.1 - 1e-05 25.3 7.4 2.5e-05 24.0 7.5 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX89479.1 - 2.1e-05 24.8 7.1 3.9e-05 23.9 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX89479.1 - 3.7e-05 23.5 7.6 0.00012 21.8 7.8 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX89479.1 - 3.9e-05 23.4 8.0 7.9e-05 22.4 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX89479.1 - 0.00042 20.3 7.0 0.005 16.8 2.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 ORX89479.1 - 0.00074 19.3 5.3 0.037 13.8 1.8 2.4 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain GAGA PF09237.11 ORX89479.1 - 0.00093 18.9 1.9 0.027 14.3 0.4 2.5 2 0 0 2 2 2 1 GAGA factor Prok-RING_4 PF14447.6 ORX89479.1 - 0.001 18.9 9.3 0.027 14.3 10.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 ORX89479.1 - 0.029 14.7 4.6 0.93 9.8 0.6 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3797 PF12677.7 ORX89479.1 - 0.038 13.9 1.6 0.038 13.9 1.6 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF3797) zf-C3HC4_4 PF15227.6 ORX89479.1 - 0.13 12.5 6.4 0.98 9.6 7.1 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORX89479.1 - 0.18 12.1 6.4 0.52 10.6 6.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX89479.1 - 0.19 11.8 3.1 0.35 11.0 3.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-WRNIP1_ubi PF18279.1 ORX89479.1 - 0.95 10.3 3.7 4.1 8.3 0.3 2.5 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain GidB PF02527.15 ORX89479.1 - 1.2 8.5 8.4 1.7 7.9 1.7 2.3 1 1 1 2 2 2 0 rRNA small subunit methyltransferase G RecR PF02132.15 ORX89479.1 - 3.3 7.4 5.4 28 4.4 1.2 2.5 2 0 0 2 2 2 0 RecR protein GPI2 PF06432.11 ORX89480.1 - 2.4e-101 338.9 17.1 2.7e-101 338.7 17.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase FA_desaturase PF00487.24 ORX89480.1 - 0.0076 16.1 2.1 0.0076 16.1 2.1 2.5 1 1 2 3 3 3 1 Fatty acid desaturase PRA1 PF03208.19 ORX89480.1 - 1 8.9 17.3 3.1 7.4 6.2 2.3 2 1 0 2 2 2 0 PRA1 family protein Ribonucleas_3_3 PF14622.6 ORX89481.1 - 4.7e-30 104.4 0.5 6.9e-30 103.8 0.5 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORX89481.1 - 1.1e-10 42.1 0.0 2.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain UPF0121 PF03661.13 ORX89482.1 - 7.1e-40 136.9 1.7 8.5e-40 136.6 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DnaJ_C PF01556.18 ORX89486.1 - 1.6e-40 138.6 0.3 2.2e-40 138.1 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORX89486.1 - 5.9e-29 100.0 4.5 9.1e-29 99.4 4.5 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 ORX89486.1 - 0.045 13.7 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein EF-hand_1 PF00036.32 ORX89487.1 - 3.5e-12 45.0 6.4 0.00021 20.6 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ORX89487.1 - 6.7e-12 44.3 5.3 5.6e-05 22.8 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 ORX89487.1 - 3.4e-09 37.0 4.5 1.1e-05 25.8 0.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORX89487.1 - 3.4e-05 23.1 6.4 0.049 13.1 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 ORX89487.1 - 4.7e-05 23.1 4.5 0.064 13.1 1.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_14 PF17959.1 ORX89487.1 - 0.0016 18.8 0.6 0.022 15.1 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain RE_SacI PF09566.10 ORX89487.1 - 0.072 12.9 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 SacI restriction endonuclease tRNA-synt_1 PF00133.22 ORX89488.1 - 1.2e-36 126.2 0.0 2.6e-25 88.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ORX89488.1 - 2e-16 59.8 0.0 4.9e-09 35.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORX89488.1 - 2.2e-16 60.2 1.1 5.3e-16 58.9 0.3 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORX89488.1 - 1.5e-08 34.4 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ORX89488.1 - 0.013 14.4 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) GHMP_kinases_N PF00288.26 ORX89489.1 - 3.4e-11 43.2 0.6 4.4e-10 39.6 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX89489.1 - 0.045 14.1 0.0 0.18 12.2 0.0 2.0 1 1 0 1 1 1 0 GHMP kinases C terminal MBT PF02820.18 ORX89490.1 - 6.7e-10 39.2 2.9 0.00011 22.4 0.1 3.0 3 0 0 3 3 3 2 mbt repeat SAWADEE PF16719.5 ORX89490.1 - 0.00021 21.3 1.7 0.21 11.6 0.1 3.3 3 0 0 3 3 3 2 SAWADEE domain AT_hook PF02178.19 ORX89490.1 - 0.039 13.8 37.8 0.25 11.3 5.1 4.0 3 0 0 3 3 3 0 AT hook motif Tudor_4 PF18358.1 ORX89490.1 - 0.041 13.5 3.3 3.8 7.2 0.4 2.7 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain T5orf172 PF10544.9 ORX89490.1 - 0.29 11.7 2.7 0.68 10.5 0.9 2.6 2 1 0 2 2 2 0 T5orf172 domain Phage_int_SAM_3 PF14659.6 ORX89490.1 - 0.48 10.7 2.5 0.58 10.5 0.8 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-CHY PF05495.12 ORX89490.1 - 4.1 7.9 13.1 2 9.0 1.0 3.8 3 0 0 3 3 3 0 CHY zinc finger Tudor-knot PF11717.8 ORX89490.1 - 5.7 6.9 11.5 8.9 6.3 0.2 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain N6_N4_Mtase PF01555.18 ORX89491.1 - 3.9e-05 23.5 0.0 0.0043 16.8 0.0 2.4 2 1 0 2 2 2 2 DNA methylase Methyltransf_11 PF08241.12 ORX89491.1 - 0.0008 20.0 0.0 0.003 18.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX89491.1 - 0.019 15.6 0.0 0.063 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.32 ORX89492.1 - 3.7e-13 49.7 9.0 0.0013 19.5 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 ORX89492.1 - 5.9e-09 36.1 0.2 1.1e-07 31.9 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORX89492.1 - 2.3e-07 31.0 0.0 0.0054 17.0 0.0 3.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TetM_leader PF08076.11 ORX89492.1 - 0.2 11.5 0.1 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide PBD PF00786.28 ORX89493.1 - 2.3e-12 47.1 0.3 2.8e-05 24.4 0.0 3.1 3 1 0 3 3 3 2 P21-Rho-binding domain zf-C2H2 PF00096.26 ORX89494.1 - 5.1e-14 51.8 25.9 7.2e-06 26.2 6.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89494.1 - 2e-13 50.1 11.0 3.7e-10 39.8 0.9 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89494.1 - 7.9e-12 45.0 22.0 0.00014 22.4 4.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX89494.1 - 2.2e-06 27.8 7.3 0.023 15.0 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX89494.1 - 8.1e-06 25.7 14.4 0.02 14.9 0.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORX89494.1 - 0.0071 16.0 1.5 0.97 9.1 0.0 2.5 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 ORX89494.1 - 0.011 16.1 6.6 0.011 16.1 6.6 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX89494.1 - 0.015 15.1 1.6 0.015 15.1 1.6 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type HypA PF01155.19 ORX89494.1 - 0.015 15.3 1.4 0.019 15.0 1.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 ORX89494.1 - 0.018 15.0 10.4 0.22 11.5 3.8 2.4 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-met PF12874.7 ORX89494.1 - 0.022 15.1 9.5 7.6 7.1 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Prok-RING_1 PF14446.6 ORX89494.1 - 0.06 13.3 3.8 8.3 6.4 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.29 ORX89494.1 - 0.068 13.1 6.1 1.4 8.9 3.2 2.2 2 0 0 2 2 2 0 PHD-finger zf_UBZ PF18439.1 ORX89494.1 - 0.14 11.8 6.0 1.3 8.7 0.4 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ORX89494.1 - 0.16 12.1 7.0 0.1 12.7 2.8 2.4 2 1 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.22 ORX89494.1 - 0.26 11.2 7.9 1.6 8.7 0.1 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 ORX89494.1 - 0.42 11.1 14.7 4.2 7.9 1.3 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zinc-ribbons_6 PF07191.12 ORX89494.1 - 0.5 10.4 5.9 8.6 6.4 5.9 2.3 1 1 0 1 1 1 0 zinc-ribbons zf-AN1 PF01428.16 ORX89494.1 - 0.67 10.2 14.8 4 7.7 8.1 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger C1_4 PF07975.12 ORX89494.1 - 1.1 9.6 8.7 1 9.6 3.1 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.15 ORX89494.1 - 1.1 9.3 14.9 0.49 10.4 0.5 3.1 1 1 2 3 3 3 0 BED zinc finger DUF4764 PF15961.5 ORX89494.1 - 1.5 7.4 6.7 1.7 7.3 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-LYAR PF08790.11 ORX89494.1 - 1.8 8.5 10.2 6.5 6.8 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-MYST PF17772.1 ORX89494.1 - 2.4 7.8 6.7 24 4.6 0.6 2.9 1 1 2 3 3 3 0 MYST family zinc finger domain zf_ZIC PF18366.1 ORX89494.1 - 4.8 7.4 10.7 1.3 9.2 0.6 2.8 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2HC_2 PF13913.6 ORX89494.1 - 9 6.3 12.9 2 8.4 1.9 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PRK PF00485.18 ORX89495.1 - 1.8e-05 24.6 0.0 0.0037 17.0 0.0 2.4 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 ORX89495.1 - 0.00021 21.2 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 ORX89495.1 - 0.00056 20.5 0.0 0.0015 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX89495.1 - 0.00058 20.0 0.1 0.0014 18.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORX89495.1 - 0.0011 19.3 0.0 0.035 14.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 ORX89495.1 - 0.0043 17.3 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORX89495.1 - 0.0048 16.1 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 ORX89495.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 ORX89495.1 - 0.0087 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ORX89495.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORX89495.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 ORX89495.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 ORX89495.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 ORX89495.1 - 0.023 14.7 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 ORX89495.1 - 0.028 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 ORX89495.1 - 0.041 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.19 ORX89495.1 - 0.041 13.5 0.1 0.06 12.9 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORX89495.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 ORX89495.1 - 0.051 13.5 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 ORX89495.1 - 0.052 13.5 0.1 0.13 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 ORX89495.1 - 0.056 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 ORX89495.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Torsin PF06309.11 ORX89495.1 - 0.061 13.4 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 1 0 Torsin AAA_28 PF13521.6 ORX89495.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX89495.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORX89495.1 - 0.17 12.3 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORX89495.1 - 0.19 11.5 0.2 0.86 9.4 0.0 2.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain MeaB PF03308.16 ORX89495.1 - 0.24 10.4 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-H2C2_2 PF13465.6 ORX89496.1 - 2.1e-13 50.0 9.4 6.8e-11 42.1 0.7 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX89496.1 - 6.1e-13 48.4 9.7 2.4e-07 30.8 4.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89496.1 - 2.6e-10 40.2 7.9 3.5e-05 24.3 2.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX89496.1 - 1.5e-06 28.0 5.9 0.0021 18.0 0.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX89496.1 - 1.5e-05 24.6 7.6 0.0063 16.2 0.3 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HE PF16278.5 ORX89496.1 - 2.2e-05 24.8 1.5 0.019 15.4 0.1 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORX89496.1 - 9.1e-05 22.6 0.3 0.21 11.9 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORX89496.1 - 0.00019 21.1 2.9 0.00019 21.1 2.9 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 ORX89496.1 - 0.0023 17.8 9.0 0.26 11.2 2.7 2.3 2 1 0 2 2 2 2 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 ORX89496.1 - 0.0024 17.9 1.5 0.06 13.5 0.1 2.1 2 0 0 2 2 2 1 Zinc ribbon domain PyrI_C PF02748.15 ORX89496.1 - 0.0026 17.6 0.7 1.4 8.9 0.1 2.1 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 ORX89496.1 - 0.0027 17.7 5.4 0.49 10.5 0.7 2.1 1 1 1 2 2 2 2 BED zinc finger zf-AN1 PF01428.16 ORX89496.1 - 0.0044 17.1 8.3 0.24 11.6 2.2 2.1 1 1 1 2 2 2 2 AN1-like Zinc finger DZR PF12773.7 ORX89496.1 - 0.012 15.6 0.6 0.015 15.3 0.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-met PF12874.7 ORX89496.1 - 0.019 15.3 2.5 4.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORX89496.1 - 0.024 15.0 1.7 1.8 8.9 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 ORX89496.1 - 0.027 14.6 1.1 1.5 9.0 0.1 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 ORX89496.1 - 0.053 14.2 2.8 2.3 8.9 0.3 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 ORX89496.1 - 0.077 12.9 2.2 6.2 6.8 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zf_RING PF16744.5 ORX89496.1 - 0.18 11.9 2.4 0.85 9.8 0.2 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger FYVE PF01363.21 ORX89496.1 - 0.18 11.9 6.5 0.55 10.4 6.5 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf_C2H2_ZHX PF18387.1 ORX89496.1 - 0.2 11.3 1.2 9.7 5.9 0.0 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_4 PF07975.12 ORX89496.1 - 0.25 11.6 3.3 5.7 7.3 3.8 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain Evr1_Alr PF04777.13 ORX89496.1 - 0.29 11.6 1.5 8.6 6.9 0.1 2.0 1 1 1 2 2 2 0 Erv1 / Alr family Spt46 PF17734.1 ORX89496.1 - 0.33 10.7 3.3 4.4 7.0 0.2 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 C5HCH PF17982.1 ORX89496.1 - 0.36 11.0 4.4 0.33 11.2 0.5 2.1 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-CHCC PF10276.9 ORX89496.1 - 0.69 10.0 6.6 0.47 10.6 1.2 2.1 2 0 0 2 2 2 0 Zinc-finger domain LPMO_10 PF03067.15 ORX89497.1 - 7.9e-07 29.9 0.4 4.4e-06 27.5 0.1 2.0 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX89497.1 - 0.028 14.4 0.1 0.075 13.0 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3657 PF12394.8 ORX89497.1 - 0.075 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein FAM135 Ribosomal_S11 PF00411.19 ORX89498.1 - 1.2e-47 160.8 1.3 1.5e-47 160.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 mRNA_cap_enzyme PF01331.19 ORX89499.1 - 1.5e-34 119.5 0.0 2.7e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORX89499.1 - 1.1e-09 38.9 0.0 2.8e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain HMGL-like PF00682.19 ORX89500.1 - 1.3e-18 67.5 0.0 1.7e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 HMGL-like zf-C2H2 PF00096.26 ORX89501.1 - 2.9e-14 52.6 11.4 6.5e-07 29.5 2.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89501.1 - 4.9e-10 39.4 8.8 5.9e-05 23.6 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX89501.1 - 2.6e-09 37.1 18.1 2.2e-05 24.7 5.5 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX89501.1 - 3.1e-05 24.1 1.6 0.00051 20.2 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX89501.1 - 0.0011 18.9 3.3 0.0078 16.2 2.3 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-TRAF PF02176.18 ORX89501.1 - 0.011 16.4 3.6 0.012 16.2 3.6 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.7 ORX89501.1 - 0.013 15.9 1.2 0.026 14.9 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORX89501.1 - 0.027 14.4 5.8 0.29 11.1 0.5 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX89501.1 - 0.3 10.9 14.1 0.53 10.1 0.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Ribosomal_L4 PF00573.22 ORX89502.1 - 1.5e-40 138.9 1.0 2.4e-40 138.3 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORX89502.1 - 3.8e-29 100.6 1.3 3.8e-29 100.6 1.3 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain phage_tail_N PF08400.10 ORX89502.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Pkinase PF00069.25 ORX89503.1 - 8.7e-72 241.6 0.3 1.2e-71 241.2 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89503.1 - 1.7e-52 178.3 0.2 2.7e-52 177.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX89503.1 - 5.5e-23 81.1 0.2 3.3e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 ORX89503.1 - 3.8e-13 49.8 0.2 8.1e-13 48.8 0.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORX89503.1 - 2.8e-06 26.9 0.1 7e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX89503.1 - 8.3e-06 24.8 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORX89503.1 - 6.4e-05 23.3 1.8 0.022 15.2 1.1 2.8 2 1 0 2 2 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 ORX89503.1 - 0.00015 20.9 1.2 0.00029 19.9 1.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORX89503.1 - 0.0094 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 ORX89503.1 - 0.018 15.0 0.1 0.062 13.2 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_9 PF15410.6 ORX89503.1 - 0.16 12.3 0.3 4.3 7.7 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain Kdo PF06293.14 ORX89503.1 - 0.19 11.1 0.2 0.41 10.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CUE PF02845.16 ORX89504.1 - 5.7e-12 45.1 2.8 2.2e-06 27.2 0.6 2.4 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.10 ORX89504.1 - 4.7e-10 39.7 2.6 8.2e-10 38.9 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORX89504.1 - 3.8e-09 36.8 0.0 8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain DMA PF03474.14 ORX89504.1 - 6.3e-05 22.5 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 DMRTA motif CLASP_N PF12348.8 ORX89505.1 - 2.8e-21 76.1 0.0 3.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 ORX89505.1 - 0.014 15.6 0.0 7.9 7.0 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat DASH_Dad1 PF08649.10 ORX89506.1 - 2.4e-08 34.0 0.2 3.8e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 TRAM_LAG1_CLN8 PF03798.16 ORX89507.1 - 8.2e-32 110.5 29.6 8.2e-32 110.5 29.6 1.8 2 1 0 2 2 2 1 TLC domain ABC_membrane PF00664.23 ORX89508.1 - 2.7e-130 433.9 32.5 1.1e-68 231.8 15.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX89508.1 - 1.2e-71 239.6 0.0 1.5e-35 122.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX89508.1 - 1.3e-18 67.3 0.3 3.3e-06 26.7 0.3 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX89508.1 - 2e-07 31.5 0.9 0.017 15.5 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX89508.1 - 5.6e-07 29.2 2.4 0.015 15.0 0.5 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORX89508.1 - 2.7e-06 26.5 1.8 0.0045 15.8 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ORX89508.1 - 4.5e-06 26.7 0.0 0.064 13.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORX89508.1 - 6.4e-06 26.5 3.8 0.1 12.9 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_21 PF13304.6 ORX89508.1 - 1.2e-05 25.3 0.0 0.44 10.3 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORX89508.1 - 1.4e-05 25.0 0.0 0.034 13.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 ORX89508.1 - 9.6e-05 22.8 2.8 7.8 6.9 0.0 4.7 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORX89508.1 - 0.00016 21.5 1.2 0.45 10.2 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORX89508.1 - 0.00041 20.9 0.0 0.13 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORX89508.1 - 0.00075 19.5 0.3 3.1 7.8 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 ORX89508.1 - 0.0012 18.1 0.3 1.6 7.9 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_23 PF13476.6 ORX89508.1 - 0.0014 19.2 0.7 2.9 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORX89508.1 - 0.0026 17.3 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 ORX89508.1 - 0.0027 17.3 0.0 2 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORX89508.1 - 0.0029 17.6 0.1 0.45 10.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 ORX89508.1 - 0.0033 17.6 2.4 4 7.7 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORX89508.1 - 0.006 16.8 0.0 5.7 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORX89508.1 - 0.0067 16.3 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase PRK PF00485.18 ORX89508.1 - 0.007 16.1 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 ORX89508.1 - 0.015 14.4 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 ORX89508.1 - 0.02 15.1 0.4 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX89508.1 - 0.02 14.9 0.0 3 7.9 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 ORX89508.1 - 0.03 13.7 0.0 0.73 9.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORX89508.1 - 0.05 14.0 0.0 15 6.1 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 ORX89508.1 - 0.054 13.2 0.1 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORX89508.1 - 0.068 12.3 0.1 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 ORX89508.1 - 0.13 12.7 0.0 40 4.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NDUF_B12 PF08122.12 ORX89508.1 - 7.1 6.8 5.2 1.7 8.7 0.6 2.4 2 0 0 2 2 1 0 NADH-ubiquinone oxidoreductase B12 subunit family AMP-binding PF00501.28 ORX89509.1 - 4.2e-91 305.7 0.0 6.1e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 ORX89509.1 - 3.5e-08 32.9 6.4 0.53 10.1 0.0 5.7 5 0 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 ORX89509.1 - 1.3e-06 29.3 0.0 2.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX89509.1 - 0.00069 19.9 0.0 0.0017 18.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 ORX89509.1 - 0.089 12.6 12.3 5.1 6.9 0.3 5.4 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase HSP70 PF00012.20 ORX89510.1 - 1.2e-262 872.5 6.9 1.3e-262 872.3 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX89510.1 - 1.8e-16 59.9 0.1 3.3e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX89510.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX89510.1 - 0.0097 15.2 0.1 0.024 13.9 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX89510.1 - 0.017 14.6 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX89510.1 - 0.082 13.1 4.9 0.79 9.9 1.0 2.4 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX89510.1 - 0.084 12.9 0.6 0.21 11.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DDR PF08841.10 ORX89510.1 - 0.094 11.7 0.3 0.82 8.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 ORX89510.1 - 0.13 11.5 0.6 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 StbA protein Dicty_CAR PF05462.11 ORX89514.1 - 6.9e-25 87.8 16.8 9.1e-25 87.4 16.8 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORX89514.1 - 0.00065 19.1 4.9 0.00065 19.1 4.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ocular_alb PF02101.15 ORX89514.1 - 0.037 12.9 3.1 2.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Ocular albinism type 1 protein AIG2_2 PF13772.6 ORX89515.1 - 6.5e-11 42.5 0.1 9.3e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 ORX89515.1 - 3.3e-09 37.4 0.1 4.3e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SKN1 PF03935.15 ORX89516.1 - 3.5e-190 632.7 8.9 8.9e-190 631.3 8.9 1.6 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sugar_tr PF00083.24 ORX89517.1 - 6.2e-100 335.2 21.9 7.9e-100 334.8 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX89517.1 - 7.4e-38 130.4 42.7 2.7e-35 121.9 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORX89517.1 - 6e-11 41.6 11.7 3.6e-07 29.1 2.4 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein Folate_carrier PF01770.18 ORX89517.1 - 8.4e-06 24.8 1.9 8.4e-06 24.8 1.9 1.5 2 0 0 2 2 2 1 Reduced folate carrier DUF1360 PF07098.11 ORX89517.1 - 0.021 14.7 0.7 0.1 12.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) MFS_3 PF05977.13 ORX89517.1 - 2 6.7 10.9 0.071 11.5 1.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2759 PF10958.8 ORX89518.1 - 0.046 13.4 0.5 0.069 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) Selenoprotein_S PF06936.11 ORX89519.1 - 0.00065 19.6 0.3 0.0014 18.5 0.2 1.5 1 1 1 2 2 2 2 Selenoprotein S (SelS) ICMT PF04140.14 ORX89520.1 - 2.3e-24 85.6 2.7 4.3e-24 84.7 2.7 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORX89520.1 - 6.4e-12 45.8 2.6 6.4e-12 45.8 2.6 2.2 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 ORX89520.1 - 0.00018 21.1 0.5 0.00023 20.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 ORX89520.1 - 0.0002 20.9 0.1 0.00027 20.5 0.1 1.2 1 0 0 1 1 1 1 NnrU protein ASFV_L11L PF05293.11 ORX89520.1 - 7.3 7.0 8.6 11 6.5 0.0 3.2 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein DPBB_1 PF03330.18 ORX89521.1 - 1.8e-10 40.9 0.0 3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX89521.1 - 7e-06 25.9 0.7 9e-06 25.5 0.7 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 ORX89522.1 - 1.3e-10 41.4 0.2 1.8e-10 41.0 0.2 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX89522.1 - 2.4e-06 27.4 0.5 2.9e-06 27.1 0.5 1.1 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 ORX89523.1 - 1.3e-10 41.4 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX89523.1 - 1.3e-05 25.1 0.7 1.6e-05 24.7 0.7 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 ORX89524.1 - 1.3e-10 41.4 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX89524.1 - 1.2e-05 25.1 0.7 1.6e-05 24.7 0.7 1.3 1 0 0 1 1 1 1 Barwin family CX9C PF16860.5 ORX89525.1 - 1.6e-20 72.8 12.0 1.8e-14 53.5 3.6 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 ORX89525.1 - 3.2e-07 30.3 9.5 9.7e-05 22.4 0.5 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 ORX89525.1 - 3.6e-05 23.7 9.6 0.0077 16.2 1.2 2.7 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like MTCP1 PF08991.10 ORX89525.1 - 0.00015 21.9 8.5 0.00043 20.4 0.8 2.3 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 ORX89525.1 - 0.0011 19.2 10.2 0.19 12.0 2.4 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 ORX89525.1 - 0.0015 18.7 13.6 0.049 13.8 3.3 2.5 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein ALMT PF11744.8 ORX89525.1 - 0.0026 16.7 0.5 0.018 13.9 0.5 1.9 1 1 0 1 1 1 1 Aluminium activated malate transporter NDUF_B7 PF05676.13 ORX89525.1 - 0.015 15.0 10.9 0.04 13.6 1.2 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) IMD PF08397.11 ORX89525.1 - 0.021 14.2 0.4 0.063 12.7 0.2 1.7 1 1 1 2 2 2 0 IRSp53/MIM homology domain TPR_17 PF13431.6 ORX89525.1 - 0.075 13.4 0.1 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89525.1 - 0.08 12.8 0.3 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat COX6B PF02297.17 ORX89525.1 - 0.34 11.2 12.7 2.2 8.6 3.0 2.6 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 ORX89525.1 - 0.64 10.5 8.9 1.4 9.4 1.8 2.9 1 1 3 4 4 4 0 GCK domain CAP PF00188.26 ORX89527.1 - 4e-08 34.1 0.1 4.4e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mg_trans_NIPA PF05653.14 ORX89528.1 - 7.5e-109 363.4 15.7 8.7e-109 363.2 15.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORX89528.1 - 8.4e-05 22.8 4.6 8.4e-05 22.8 4.6 3.5 3 1 0 3 3 3 1 EamA-like transporter family DUF2937 PF11157.8 ORX89528.1 - 0.4 10.4 5.1 1.1 8.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Fis1_TPR_C PF14853.6 ORX89529.1 - 1.1e-24 86.3 0.1 1.8e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORX89529.1 - 5.7e-10 38.7 0.2 1.5e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ORX89529.1 - 1.3e-05 24.9 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89529.1 - 0.0023 18.4 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX89529.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89529.1 - 0.01 16.5 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX89529.1 - 0.018 15.6 0.0 0.043 14.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89529.1 - 0.021 15.6 0.0 0.048 14.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat COPI_C PF06957.11 ORX89529.1 - 0.069 11.9 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ANAPC3 PF12895.7 ORX89529.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L1 PF00687.21 ORX89530.1 - 1.6e-65 220.6 5.2 1.9e-65 220.4 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Elongin_A PF06881.11 ORX89530.1 - 0.32 11.6 3.8 0.64 10.6 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Halogen_Hydrol PF10112.9 ORX89530.1 - 0.67 9.9 3.6 0.81 9.7 0.7 2.3 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CAP PF00188.26 ORX89531.1 - 4e-15 56.8 0.7 5.1e-15 56.4 0.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PIF1 PF05970.14 ORX89532.1 - 2e-16 60.1 0.1 2.7e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 ORX89532.1 - 2.1e-10 40.6 0.0 2.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 ORX89532.1 - 3.7e-05 22.8 0.1 5.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 ORX89532.1 - 9.6e-05 22.8 0.1 0.00014 22.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX89532.1 - 0.00018 21.9 0.1 0.00027 21.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORX89532.1 - 0.00024 21.0 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 ORX89532.1 - 0.00068 19.6 0.1 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 NTPase TrwB_AAD_bind PF10412.9 ORX89532.1 - 0.0024 16.8 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 ORX89532.1 - 0.0051 16.8 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 ORX89532.1 - 0.0052 16.8 0.1 0.0076 16.3 0.1 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 ORX89532.1 - 0.0058 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORX89532.1 - 0.0079 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 ORX89532.1 - 0.0089 16.0 0.1 0.019 15.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 ORX89532.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF815 PF05673.13 ORX89532.1 - 0.022 13.9 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORX89532.1 - 0.023 15.1 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 ORX89532.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 ORX89532.1 - 0.031 14.8 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 ORX89532.1 - 0.046 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.19 ORX89532.1 - 0.054 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORX89532.1 - 0.057 14.0 0.1 0.13 12.8 0.1 1.6 1 1 1 2 2 1 0 AAA domain AAA_7 PF12775.7 ORX89532.1 - 0.063 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 ORX89532.1 - 0.075 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DEAD PF00270.29 ORX89532.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 ORX89532.1 - 0.099 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Sigma54_activat PF00158.26 ORX89532.1 - 0.099 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 ORX89532.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 ORX89532.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 ORX89532.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORX89532.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.23 ORX89532.1 - 0.13 11.3 0.0 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_33 PF13671.6 ORX89532.1 - 0.14 12.4 0.2 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORX89532.1 - 0.15 11.8 0.1 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 ORX89532.1 - 0.2 11.3 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase GTP_EFTU PF00009.27 ORX89533.1 - 5e-09 36.0 0.0 5e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Rer1 PF03248.13 ORX89534.1 - 1.1e-80 269.3 6.8 1.3e-80 269.1 6.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 ORX89534.1 - 1.1 8.8 8.5 0.062 12.9 2.9 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF4131 PF13567.6 ORX89534.1 - 9 5.9 8.6 16 5.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L28e PF01778.17 ORX89535.1 - 1.4e-35 122.5 1.3 1.9e-35 122.1 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family IF-2B PF01008.17 ORX89536.1 - 7e-74 248.6 0.1 8.1e-74 248.3 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CAF1 PF04857.20 ORX89537.1 - 2.2e-20 73.1 0.0 2.4e-09 36.8 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease zf-Tim10_DDP PF02953.15 ORX89538.1 - 3.2e-23 81.1 0.4 4e-23 80.8 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L18A PF01775.17 ORX89539.1 - 1.8e-46 157.2 0.8 2.1e-46 156.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A RRM_1 PF00076.22 ORX89540.1 - 1.5e-09 37.5 1.0 0.00043 20.1 0.4 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORX89540.1 - 2.1e-05 24.5 10.3 0.001 19.1 0.0 3.4 4 0 0 4 4 4 2 RNA binding motif zf-CCCH PF00642.24 ORX89540.1 - 3.8e-05 23.5 2.0 7.1e-05 22.6 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.17 ORX89540.1 - 4.7e-05 23.6 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 ORX89540.1 - 0.00017 21.5 0.8 0.085 12.9 0.2 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 ORX89540.1 - 0.0052 16.8 1.4 0.0098 15.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger domain DUF2533 PF10752.9 ORX89540.1 - 0.37 11.3 4.6 0.9 10.0 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) DUF4461 PF14688.6 ORX89540.1 - 0.37 10.5 4.5 0.74 9.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) MMS1_N PF10433.9 ORX89541.1 - 4.8e-161 536.7 0.0 7.1e-161 536.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORX89541.1 - 7.9e-96 321.2 0.0 4.7e-94 315.3 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 ORX89541.1 - 0.00093 19.5 0.0 0.072 13.4 0.0 3.3 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Lactamase_B_6 PF16661.5 ORX89542.1 - 1.6e-66 223.5 0.0 2.7e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 ORX89542.1 - 6e-38 130.7 0.2 1.5e-30 106.6 0.0 2.7 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 ORX89542.1 - 2.9e-21 75.8 0.1 1.2e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 ORX89542.1 - 3.8e-10 39.5 0.0 8.9e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 ORX89542.1 - 0.00011 22.3 0.1 0.00021 21.4 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX89542.1 - 0.034 13.6 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Med7 PF05983.11 ORX89543.1 - 4.6e-61 206.3 5.9 7e-61 205.7 5.9 1.2 1 0 0 1 1 1 1 MED7 protein Utp12 PF04003.12 ORX89543.1 - 0.019 15.3 0.8 0.028 14.7 0.8 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF4530 PF15039.6 ORX89543.1 - 0.053 13.7 0.3 0.095 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) eIF-5a PF01287.20 ORX89544.1 - 1.1e-27 95.9 0.3 1.6e-27 95.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORX89544.1 - 0.0055 16.7 0.5 0.0093 16.0 0.1 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Methyltransf_4 PF02390.17 ORX89545.1 - 6.1e-58 195.1 0.0 7.5e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 ORX89545.1 - 0.0062 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX89545.1 - 0.013 15.0 0.0 0.09 12.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 ORX89545.1 - 0.067 13.8 0.0 0.32 11.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain HEXIM PF15313.6 ORX89546.1 - 1.8 8.8 15.1 0.17 12.1 7.1 2.0 1 1 1 2 2 2 0 Hexamethylene bis-acetamide-inducible protein D123 PF07065.14 ORX89546.1 - 2.5 7.1 5.8 1.2 8.2 3.9 1.4 1 1 0 1 1 1 0 D123 Nop14 PF04147.12 ORX89546.1 - 3.6 5.7 18.4 4.4 5.4 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family NIF PF03031.18 ORX89547.1 - 1.3e-27 96.5 0.8 3.2e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 ORX89547.1 - 4.6e-07 30.1 0.0 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORX89547.1 - 6.7e-07 29.2 0.0 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain DUF874 PF05917.11 ORX89547.1 - 0.00041 19.5 0.5 0.00061 18.9 0.5 1.2 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) BRCT_2 PF16589.5 ORX89547.1 - 0.0039 17.6 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Activator_LAG-3 PF11498.8 ORX89547.1 - 0.035 13.1 7.1 0.058 12.4 7.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 LIG3_BRCT PF16759.5 ORX89547.1 - 0.15 12.4 1.2 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain SH2_2 PF14633.6 ORX89548.1 - 1.3e-76 256.8 0.0 2.4e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 ORX89548.1 - 1.8e-37 128.5 0.0 3.4e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 ORX89548.1 - 1.6e-32 112.0 0.0 3.4e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 ORX89548.1 - 9.2e-28 97.0 1.4 9.2e-28 97.0 1.4 2.0 2 0 0 2 2 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.23 ORX89548.1 - 1.3e-08 35.0 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Tex_YqgF PF16921.5 ORX89548.1 - 1.8e-06 28.4 0.0 4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 ORX89548.1 - 6.8e-05 23.0 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 ORX89548.1 - 0.00013 21.7 10.3 0.036 13.8 0.1 3.8 5 1 0 5 5 5 2 Tex-like protein N-terminal domain HHH_9 PF17674.1 ORX89548.1 - 0.00013 22.8 5.0 0.00054 20.8 2.9 3.3 3 1 0 3 3 3 1 HHH domain SH2 PF00017.24 ORX89548.1 - 0.00022 21.3 0.0 0.00063 19.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DUF1896 PF08989.10 ORX89548.1 - 0.033 14.3 0.6 0.092 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) WD40 PF00400.32 ORX89549.1 - 6.1e-41 137.6 15.9 7.4e-08 32.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89549.1 - 2.4e-17 63.0 0.0 0.00031 21.0 0.1 5.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX89549.1 - 0.00014 21.8 0.0 0.17 11.7 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX89549.1 - 0.00052 19.4 0.0 0.06 12.7 0.0 3.2 3 1 1 4 4 4 1 WD40-like domain Nup160 PF11715.8 ORX89549.1 - 0.015 13.9 0.5 1.5 7.3 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORX89549.1 - 0.081 11.4 0.0 0.17 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ret2_MD PF18528.1 ORX89549.1 - 0.11 12.8 0.0 28 5.2 0.0 3.1 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Ribosomal_S3Ae PF01015.18 ORX89550.1 - 8.1e-94 312.9 1.3 1e-93 312.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 ORX89550.1 - 0.027 15.0 0.2 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 ORX89550.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Kelch_5 PF13854.6 ORX89552.1 - 0.0085 16.1 2.3 0.96 9.5 0.1 3.0 3 0 0 3 3 3 2 Kelch motif PTR2 PF00854.21 ORX89553.1 - 1.2e-66 225.2 4.3 1.6e-66 224.8 4.3 1.1 1 0 0 1 1 1 1 POT family FoP_duplication PF13865.6 ORX89554.1 - 1.9e-17 63.6 10.0 1.9e-17 63.6 10.0 2.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 SPRY PF00622.28 ORX89555.1 - 2.5e-18 66.4 0.0 4.2e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 ORX89555.1 - 6.7e-10 38.7 6.6 1.1e-09 38.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX89555.1 - 0.0024 17.7 6.7 0.0047 16.8 6.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TIP120 PF08623.10 ORX89555.1 - 0.069 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) zf-RING_2 PF13639.6 ORX89555.1 - 0.16 12.3 8.6 0.29 11.5 8.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 ORX89555.1 - 3.9 7.5 7.8 6.8 6.7 7.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Polysacc_deac_1 PF01522.21 ORX89556.1 - 2e-12 47.1 0.0 8.5e-12 45.1 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide deacetylase Stealth_CR2 PF11380.8 ORX89556.1 - 0.21 11.8 0.1 0.51 10.5 0.0 1.6 2 0 0 2 2 2 0 Stealth protein CR2, conserved region 2 TPR_2 PF07719.17 ORX89557.1 - 2.2e-34 114.8 1.2 7.4e-05 22.6 0.0 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89557.1 - 5e-33 111.6 3.8 9.8e-07 28.3 0.0 7.8 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORX89557.1 - 1.3e-22 78.0 4.0 0.00046 20.2 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89557.1 - 2.1e-17 63.5 0.0 0.00011 22.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89557.1 - 9.2e-17 61.3 0.1 3e-05 24.4 0.2 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89557.1 - 9e-16 57.9 0.0 2.8e-05 24.3 0.1 5.6 5 2 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89557.1 - 1.1e-14 53.9 0.3 0.38 11.7 0.1 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89557.1 - 1.6e-14 53.3 7.0 0.0011 18.5 0.3 6.0 4 1 3 7 7 7 3 TPR repeat ANAPC3 PF12895.7 ORX89557.1 - 4.8e-14 52.3 1.0 0.00011 22.3 0.6 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORX89557.1 - 2e-13 49.3 0.1 0.026 14.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORX89557.1 - 9.9e-12 44.4 1.1 0.26 11.8 0.0 6.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORX89557.1 - 2.3e-09 37.3 0.0 0.079 13.1 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORX89557.1 - 2.6e-08 34.0 5.8 1.5 9.6 0.0 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORX89557.1 - 9.5e-08 31.6 0.1 0.03 13.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX89557.1 - 0.00032 20.2 0.1 0.056 12.8 0.1 3.0 2 1 1 3 3 3 2 MalT-like TPR region TPR_10 PF13374.6 ORX89557.1 - 0.0019 18.0 0.1 65 3.6 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 ORX89557.1 - 0.002 18.6 0.2 6.2 7.2 0.1 3.6 4 1 1 5 5 4 1 Bacterial transcriptional activator domain MIT PF04212.18 ORX89557.1 - 0.0068 16.5 1.0 3.8 7.6 0.0 4.1 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain PPTA PF01239.22 ORX89557.1 - 0.01 15.5 0.7 0.14 11.9 0.2 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_21 PF09976.9 ORX89557.1 - 0.012 15.4 0.0 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain NARP1 PF12569.8 ORX89557.1 - 0.027 13.4 0.1 0.28 10.1 0.0 2.2 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PPR PF01535.20 ORX89557.1 - 0.033 14.4 2.0 42 4.7 0.0 4.2 4 0 0 4 4 4 0 PPR repeat MAS20 PF02064.15 ORX89557.1 - 0.13 12.4 0.0 35 4.5 0.0 2.9 3 1 0 3 3 3 0 MAS20 protein import receptor DUF3856 PF12968.7 ORX89557.1 - 0.2 11.7 0.4 33 4.5 0.0 3.7 4 1 1 5 5 4 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 ORX89558.1 - 1.7e-15 57.0 6.5 2.4e-15 56.5 4.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ORX89558.1 - 6.7e-12 44.7 1.4 9.6e-08 31.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORX89558.1 - 1.8e-11 43.2 1.9 8e-07 28.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX89558.1 - 3.5e-08 33.0 0.6 2.9e-05 23.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89558.1 - 7.6e-07 29.3 0.2 0.0011 19.2 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORX89558.1 - 5.2e-06 26.5 0.7 0.061 13.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89558.1 - 0.00014 22.3 0.3 1.6 9.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89558.1 - 0.00085 19.9 0.1 0.11 13.4 0.0 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX89558.1 - 0.0014 18.5 0.4 1.2 9.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 ORX89558.1 - 0.0072 15.3 0.1 1.9 7.3 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 ORX89558.1 - 0.0087 16.7 0.2 0.39 11.4 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC8 PF04049.13 ORX89558.1 - 0.009 16.1 0.5 0.025 14.7 0.5 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_6 PF13174.6 ORX89558.1 - 0.026 15.1 0.1 2.7 8.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX89558.1 - 0.028 14.3 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORX89558.1 - 0.038 14.0 0.9 0.091 12.8 0.5 1.8 1 1 1 2 2 2 0 Putative TPR-like repeat Arrestin_N PF00339.29 ORX89559.1 - 3.1e-09 37.0 0.9 6.9e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX89559.1 - 0.0002 21.8 0.8 0.00057 20.4 0.8 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX89559.1 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like DUF4130 PF13566.6 ORX89559.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 PALP PF00291.25 ORX89563.1 - 2.8e-15 56.5 0.3 3.5e-15 56.2 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FRG1 PF06229.12 ORX89564.1 - 1.1e-35 123.1 0.3 1.1e-35 123.1 0.3 1.7 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 ORX89564.1 - 1.9e-05 24.8 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Fascin domain Tetraspanin PF00335.20 ORX89565.1 - 5e-12 46.0 7.5 6.5e-12 45.6 7.5 1.2 1 0 0 1 1 1 1 Tetraspanin family Sre PF03125.18 ORX89565.1 - 0.027 13.6 1.5 0.041 13.0 1.5 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor MitoNEET_N PF10660.9 ORX89565.1 - 0.82 9.7 3.2 1.1 9.4 0.2 2.5 1 1 1 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus bZIP_1 PF00170.21 ORX89567.1 - 0.00054 20.0 13.7 0.0017 18.4 10.3 2.8 2 1 1 3 3 3 2 bZIP transcription factor SIKE PF05769.11 ORX89567.1 - 0.026 14.4 0.8 0.042 13.8 0.8 1.2 1 0 0 1 1 1 0 SIKE family PAP1 PF08601.10 ORX89567.1 - 0.027 14.2 0.0 0.027 14.2 0.0 2.7 2 1 1 3 3 3 0 Transcription factor PAP1 bZIP_2 PF07716.15 ORX89567.1 - 0.27 11.3 10.1 0.32 11.1 0.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Ras PF00071.22 ORX89568.1 - 7.3e-38 129.7 0.0 7.9e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89568.1 - 7.7e-16 58.4 0.0 9.2e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89568.1 - 0.00011 21.7 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Tubulin PF00091.25 ORX89569.1 - 3e-69 233.2 0.0 4.6e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX89569.1 - 4.8e-46 156.0 0.8 7.4e-46 155.4 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX89569.1 - 3.6e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4430 PF14478.6 ORX89569.1 - 0.035 14.7 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) CN_hydrolase PF00795.22 ORX89570.1 - 3.5e-13 49.5 0.0 5.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PHD PF00628.29 ORX89571.1 - 0.00056 19.8 3.5 0.001 18.9 3.5 1.5 1 0 0 1 1 1 1 PHD-finger TFIIE_alpha PF02002.17 ORX89571.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Fe_dep_repress PF01325.19 ORX89571.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 ORX89571.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MIP PF00230.20 ORX89573.1 - 4.3e-53 180.4 10.2 5.2e-53 180.1 10.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein nlz1 PF12402.8 ORX89573.1 - 0.07 13.6 0.4 0.2 12.1 0.4 1.7 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 DUF2070 PF09843.9 ORX89573.1 - 0.089 11.1 3.9 0.11 10.8 0.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MIP PF00230.20 ORX89574.1 - 3.3e-53 180.7 10.4 4e-53 180.4 10.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein nlz1 PF12402.8 ORX89574.1 - 0.055 13.9 0.4 0.19 12.2 0.4 1.9 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 DUF3522 PF12036.8 ORX89574.1 - 0.19 12.0 2.6 0.2 12.0 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) Zwilch PF09817.9 ORX89575.1 - 1.3e-17 63.5 0.1 2e-16 59.6 0.0 2.2 1 1 1 2 2 2 2 RZZ complex, subunit zwilch XPG_N PF00752.17 ORX89576.1 - 7e-34 116.3 0.0 1.2e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORX89576.1 - 1.5e-32 111.8 0.1 3e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 ORX89576.1 - 1e-06 29.2 0.0 3.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.15 ORX89576.1 - 0.0073 16.4 0.0 0.21 11.7 0.0 2.9 3 0 0 3 3 3 1 Iron dependent repressor, metal binding and dimerisation domain HHH_5 PF14520.6 ORX89576.1 - 0.019 15.5 0.1 0.083 13.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Prefoldin PF02996.17 ORX89576.1 - 0.13 12.2 0.1 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit HHH_2 PF12826.7 ORX89576.1 - 0.15 12.2 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif DFP PF04127.15 ORX89577.1 - 1.9e-16 60.4 0.0 2.4e-11 43.8 0.0 2.6 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein PX PF00787.24 ORX89579.1 - 2.7e-25 88.6 0.1 6e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 ORX89579.1 - 3.1e-21 75.9 3.4 3.6e-20 72.4 3.4 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 ORX89579.1 - 2.8e-08 33.2 0.1 5.2e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX89579.1 - 6e-08 32.4 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX89579.1 - 1.1e-06 28.2 0.0 2.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PI3K_P85_iSH2 PF16454.5 ORX89579.1 - 0.093 12.3 2.1 4.8 6.8 1.1 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Vps5 PF09325.10 ORX89579.1 - 0.9 9.0 5.4 0.68 9.4 0.7 2.7 3 0 0 3 3 3 0 Vps5 C terminal like Amidohydro_1 PF01979.20 ORX89580.1 - 3.5e-72 243.6 0.9 5.1e-72 243.1 0.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORX89580.1 - 6e-57 191.2 4.5 1.4e-56 190.0 4.5 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORX89580.1 - 8.9e-39 131.5 0.1 1.8e-38 130.5 0.1 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 ORX89580.1 - 3.1e-38 130.1 0.4 7.7e-38 128.8 0.4 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORX89580.1 - 1.5e-06 28.0 3.0 4.5e-06 26.4 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase family AAA PF00004.29 ORX89581.1 - 1.1e-14 55.0 0.0 2.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX89581.1 - 3.2e-05 24.0 0.0 7.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX89581.1 - 0.00061 20.1 0.0 0.0019 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX89581.1 - 0.001 19.5 0.0 0.0023 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 ORX89581.1 - 0.03 13.7 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 ORX89581.1 - 0.042 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORX89581.1 - 0.055 13.4 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 ORX89581.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORX89581.1 - 0.071 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORX89581.1 - 0.086 12.4 0.1 0.31 10.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 ORX89581.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORX89581.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 ORX89581.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORX89581.1 - 0.18 11.5 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein p450 PF00067.22 ORX89582.1 - 2.3e-34 119.0 0.1 2.9e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 PALP PF00291.25 ORX89583.1 - 9.3e-55 186.1 0.0 1.1e-54 185.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LRR_9 PF14580.6 ORX89584.1 - 2.5e-69 232.2 1.6 3.2e-69 231.9 1.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORX89584.1 - 1.7e-10 40.5 11.5 6e-10 38.7 6.5 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 ORX89584.1 - 2.1e-10 40.6 15.7 4.9e-07 30.0 4.7 4.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX89584.1 - 0.063 13.8 9.8 14 6.7 0.1 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat DUF3954 PF13128.6 ORX89584.1 - 0.077 12.8 0.1 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3954) DUF2482 PF10655.9 ORX89584.1 - 0.092 13.3 0.3 0.22 12.1 0.1 1.7 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) LRR_6 PF13516.6 ORX89584.1 - 1.2 9.4 11.5 34 4.8 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Cpn60_TCP1 PF00118.24 ORX89585.1 - 1.6e-152 508.6 18.4 1.9e-152 508.4 18.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SCAB_CC PF16712.5 ORX89585.1 - 0.021 14.7 1.4 0.039 13.8 0.2 2.0 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Sua5_yciO_yrdC PF01300.18 ORX89585.1 - 0.025 14.1 0.2 0.094 12.2 0.1 1.9 2 0 0 2 2 2 0 Telomere recombination DUF2358 PF10184.9 ORX89586.1 - 2.2e-13 50.4 0.0 1.8e-10 41.1 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 ORX89586.1 - 1e-06 28.1 0.3 0.00054 19.2 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Ras PF00071.22 ORX89587.1 - 8.7e-54 181.5 0.0 1e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89587.1 - 6.1e-19 68.4 0.0 8.4e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89587.1 - 1e-06 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX89587.1 - 0.077 12.5 0.0 0.6 9.6 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 ORX89587.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Rnk_N PF14760.6 ORX89587.1 - 0.31 11.5 1.5 1.5 9.3 0.2 2.1 2 0 0 2 2 2 0 Rnk N-terminus Pkinase PF00069.25 ORX89588.1 - 3.4e-60 203.6 0.0 8.1e-59 199.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89588.1 - 3.1e-42 144.6 0.0 5.4e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORX89588.1 - 8.7e-05 22.7 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 ORX89588.1 - 0.00028 19.8 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF3818 PF12825.7 ORX89589.1 - 1.1e-80 271.2 6.1 1.9e-80 270.4 6.1 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Cyclin PF08613.11 ORX89589.1 - 3.3e-34 118.6 0.3 1.4e-33 116.6 0.3 2.1 1 0 0 1 1 1 1 Cyclin PXB PF12828.7 ORX89589.1 - 1.3e-14 54.2 2.1 1.3e-14 54.2 2.1 2.4 2 0 0 2 2 2 1 PX-associated PX PF00787.24 ORX89589.1 - 6.3e-10 39.0 1.5 5.4e-09 36.0 0.2 2.9 2 0 0 2 2 2 1 PX domain Cyclin_N PF00134.23 ORX89589.1 - 1.2e-06 28.3 0.1 3.5e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain RNA_pol_3_Rpc31 PF11705.8 ORX89590.1 - 1.6e-29 103.8 6.8 2.4e-29 103.2 6.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PHO4 PF01384.20 ORX89591.1 - 2.8e-118 394.8 17.2 3.3e-118 394.6 17.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF1240 PF06836.12 ORX89591.1 - 0.18 12.3 0.8 0.98 10.0 0.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) PHO4 PF01384.20 ORX89592.1 - 2.1e-120 401.8 11.8 2.4e-120 401.6 11.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Trp_DMAT PF11991.8 ORX89592.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase DUF1240 PF06836.12 ORX89592.1 - 0.15 12.7 0.6 0.73 10.4 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) PHO4 PF01384.20 ORX89593.1 - 3.1e-119 398.0 13.9 3.6e-119 397.7 13.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Rhabdo_M2 PF04785.12 ORX89593.1 - 0.091 12.1 0.3 7.1 5.9 0.0 2.6 3 0 0 3 3 3 0 Rhabdovirus matrix protein M2 DUF1240 PF06836.12 ORX89593.1 - 0.14 12.7 0.6 0.71 10.4 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) RRM_3 PF08777.11 ORX89594.1 - 1.7e-10 40.9 1.7 1e-07 31.9 0.0 3.0 2 1 1 3 3 3 2 RNA binding motif RRM_1 PF00076.22 ORX89594.1 - 9.2e-08 31.8 0.2 2.4e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 ORX89594.1 - 1.2e-07 31.7 0.0 4e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 La domain Ank_4 PF13637.6 ORX89595.1 - 5.5e-09 36.4 0.2 1.3e-05 25.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX89595.1 - 1.5e-07 31.9 0.0 0.033 14.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX89595.1 - 1.3e-06 28.2 1.2 0.02 15.4 0.2 3.3 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.6 ORX89595.1 - 2.7e-05 24.4 0.2 0.018 15.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORX89595.1 - 5.7e-05 23.4 0.6 0.0099 16.3 0.5 2.7 2 0 0 2 2 2 1 Ankyrin repeat KilA-N PF04383.13 ORX89595.1 - 7.5e-05 22.6 0.1 0.0012 18.7 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Filament PF00038.21 ORX89595.1 - 0.00049 19.8 11.7 0.0092 15.6 7.1 2.2 2 0 0 2 2 2 1 Intermediate filament protein Leu_zip PF15294.6 ORX89595.1 - 0.0084 15.7 5.4 0.0084 15.7 5.4 1.6 2 0 0 2 2 2 1 Leucine zipper TMF_TATA_bd PF12325.8 ORX89595.1 - 0.0097 16.1 16.0 0.23 11.7 9.2 2.6 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ORX89595.1 - 0.016 15.7 12.5 0.036 14.5 12.5 1.6 1 0 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 ORX89595.1 - 0.028 14.6 9.6 1.5 9.0 7.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 ORX89595.1 - 0.064 12.1 13.8 0.054 12.4 8.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 ORX89595.1 - 0.11 12.5 9.1 6.8 6.7 7.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 ORX89595.1 - 0.35 9.7 3.6 0.52 9.1 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 ORX89595.1 - 0.39 9.3 4.8 0.74 8.4 3.7 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Yuri_gagarin PF15934.5 ORX89595.1 - 0.43 10.4 9.0 0.06 13.2 4.2 1.9 2 0 0 2 2 2 0 Yuri gagarin CENP-F_leu_zip PF10473.9 ORX89595.1 - 0.43 10.6 15.2 2 8.4 10.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 ORX89595.1 - 0.48 8.7 19.3 1.8 6.9 19.3 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein LXG PF04740.12 ORX89595.1 - 0.6 9.8 7.7 1.4 8.6 7.7 1.6 1 0 0 1 1 1 0 LXG domain of WXG superfamily YabA PF06156.13 ORX89595.1 - 0.68 10.6 10.7 3.2 8.4 0.5 2.6 2 0 0 2 2 2 0 Initiation control protein YabA OmpH PF03938.14 ORX89595.1 - 0.72 10.2 17.8 0.084 13.2 11.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FTA4 PF13093.6 ORX89595.1 - 0.93 9.3 9.9 2.5 7.9 9.7 1.9 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NPV_P10 PF05531.12 ORX89595.1 - 1.1 9.8 8.4 0.87 10.1 2.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 ORX89595.1 - 1.1 9.1 10.1 1.4 8.7 7.4 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF4763 PF15960.5 ORX89595.1 - 1.3 8.2 13.5 0.18 11.1 7.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ADIP PF11559.8 ORX89595.1 - 2.5 8.2 15.5 3.1 7.9 7.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.10 ORX89595.1 - 2.6 8.4 12.9 0.91 9.9 3.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 ORX89595.1 - 2.9 8.3 9.0 33 5.0 0.1 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) RRP36 PF06102.12 ORX89595.1 - 3.1 7.7 15.8 0.48 10.4 6.8 2.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Exonuc_VII_L PF02601.15 ORX89595.1 - 4.5 6.7 13.6 12 5.4 13.6 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 ORX89595.1 - 7.9 6.0 9.5 0.79 9.3 5.0 1.5 2 0 0 2 2 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MPS2 PF17060.5 ORX89595.1 - 8.2 5.6 8.7 21 4.2 8.7 1.6 1 1 0 1 1 1 0 Monopolar spindle protein 2 Prp18 PF02840.15 ORX89596.1 - 2.3e-65 219.0 0.4 2.3e-65 219.0 0.4 2.2 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 ORX89596.1 - 2.7e-11 42.8 2.6 5.8e-11 41.7 2.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ELFV_dehydrog_N PF02812.18 ORX89597.1 - 7.9e-57 190.7 0.0 1.4e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX89597.1 - 8.2e-57 192.7 1.1 1.3e-55 188.8 0.2 2.1 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORX89597.1 - 0.029 11.9 0.0 0.05 11.1 0.0 1.3 1 1 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase NAD_binding_7 PF13241.6 ORX89597.1 - 0.038 14.4 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TRL PF13146.6 ORX89597.1 - 0.053 13.8 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 TRL-like protein family 2-Hacid_dh_C PF02826.19 ORX89597.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORX89598.1 - 5.2e-57 193.4 1.2 6.9e-56 189.7 0.4 2.1 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORX89598.1 - 1.7e-55 186.4 0.0 3.1e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Bac_GDH PF05088.12 ORX89598.1 - 0.021 12.4 0.1 0.043 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase NAD_binding_7 PF13241.6 ORX89598.1 - 0.037 14.5 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORX89598.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORX89599.1 - 4.2e-57 193.6 1.4 4.9e-56 190.2 0.4 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORX89599.1 - 1.1e-55 187.0 0.0 2e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Bac_GDH PF05088.12 ORX89599.1 - 0.021 12.4 0.1 0.043 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase NAD_binding_7 PF13241.6 ORX89599.1 - 0.039 14.4 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORX89599.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORX89600.1 - 4.1e-56 190.4 2.6 3.1e-55 187.6 0.9 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORX89600.1 - 1.7e-55 186.4 0.0 3.1e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Bac_GDH PF05088.12 ORX89600.1 - 0.012 13.2 0.1 0.024 12.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase NAD_binding_7 PF13241.6 ORX89600.1 - 0.047 14.1 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORX89600.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORX89601.1 - 5e-57 193.4 1.2 6.8e-56 189.7 0.4 2.1 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORX89601.1 - 1.7e-55 186.4 0.0 3.1e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Bac_GDH PF05088.12 ORX89601.1 - 0.021 12.4 0.1 0.042 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase NAD_binding_7 PF13241.6 ORX89601.1 - 0.038 14.4 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ORX89601.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog_N PF02812.18 ORX89602.1 - 3.7e-47 159.5 0.0 7.5e-47 158.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX89602.1 - 2.5e-27 96.2 5.1 7.4e-12 45.5 0.4 4.2 1 1 3 4 4 4 3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ORX89602.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRL PF13146.6 ORX89602.1 - 0.14 12.5 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 TRL-like protein family Skp1_POZ PF03931.15 ORX89603.1 - 6.7e-10 39.0 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 ORX89603.1 - 0.033 14.4 0.1 0.048 13.9 0.1 1.3 1 1 0 1 1 1 0 BTB/POZ domain Rif1_N PF12231.8 ORX89603.1 - 0.076 12.0 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal RsgA_GTPase PF03193.16 ORX89605.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_11 PF13086.6 ORX89605.1 - 0.26 11.1 1.5 0.45 10.3 0.3 1.9 2 0 0 2 2 2 0 AAA domain Putative_PNPOx PF01243.20 ORX89606.1 - 0.0028 17.8 0.0 0.007 16.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ras PF00071.22 ORX89607.1 - 8.5e-65 217.3 0.2 9.8e-65 217.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89607.1 - 1.5e-36 125.2 0.1 2.1e-36 124.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89607.1 - 4.2e-16 58.9 0.1 5e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX89607.1 - 6.7e-07 28.9 0.2 8.5e-07 28.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX89607.1 - 5.1e-06 26.2 0.7 1e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX89607.1 - 5.8e-06 26.4 0.1 3e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX89607.1 - 6.3e-05 22.9 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORX89607.1 - 0.0027 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 ORX89607.1 - 0.02 14.6 0.1 0.5 10.1 0.1 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ORX89607.1 - 0.035 13.8 0.2 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX89607.1 - 0.081 13.3 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 ORX89607.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 ORX89607.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein zf-C2H2 PF00096.26 ORX89608.1 - 1.1e-08 35.0 15.4 3.9e-05 23.9 8.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89608.1 - 2.7e-07 30.7 3.2 2.7e-07 30.7 3.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89608.1 - 2e-06 28.1 13.1 0.00097 19.8 6.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.18 ORX89608.1 - 0.019 15.7 4.0 0.028 15.1 4.0 1.4 1 1 0 1 1 1 0 TRAF-type zinc finger Crust_neurohorm PF01147.17 ORX89608.1 - 0.049 13.5 0.9 0.066 13.0 0.9 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family zf-C2HE PF16278.5 ORX89608.1 - 0.066 13.7 1.6 0.066 13.7 1.6 1.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 ORX89608.1 - 0.11 12.3 2.3 0.11 12.3 2.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Herpes_UL43 PF05072.13 ORX89608.1 - 0.31 10.1 0.9 0.32 10.1 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL43 protein zf-C2H2_6 PF13912.6 ORX89608.1 - 3.7 7.6 13.7 1.6 8.8 8.0 3.0 2 2 0 2 2 2 0 C2H2-type zinc finger CoaE PF01121.20 ORX89610.1 - 5.9e-18 65.2 0.1 6.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 ORX89610.1 - 0.00078 20.0 0.1 0.012 16.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 ORX89610.1 - 0.0065 16.9 0.1 4.3 7.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 ORX89610.1 - 0.081 13.0 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Melittin PF01372.17 ORX89610.1 - 0.4 10.7 2.9 4.4 7.5 0.1 3.4 3 0 0 3 3 3 0 Melittin Mg_trans_NIPA PF05653.14 ORX89611.1 - 3e-87 292.5 24.0 6.2e-87 291.4 24.0 1.5 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORX89611.1 - 7.1e-08 32.7 7.8 7.1e-08 32.7 7.8 2.7 2 1 0 2 2 2 1 EamA-like transporter family DUF5362 PF17319.2 ORX89611.1 - 0.045 13.6 0.4 0.045 13.6 0.4 3.1 2 2 1 3 3 3 0 Family of unknown function (DUF5362) zf-RING_2 PF13639.6 ORX89613.1 - 3.4e-14 52.9 14.3 8.4e-13 48.4 10.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 ORX89613.1 - 1.9e-08 33.9 10.0 1.9e-08 33.9 10.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORX89613.1 - 6.7e-08 32.3 13.8 4.4e-07 29.7 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX89613.1 - 2.6e-07 30.8 12.7 9.5e-07 29.0 12.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORX89613.1 - 2.7e-07 30.3 14.4 4.8e-07 29.5 10.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX89613.1 - 0.00017 21.4 12.4 0.0016 18.3 7.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX89613.1 - 0.00045 20.1 9.1 0.00045 20.1 9.1 2.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX89613.1 - 0.0031 17.5 13.2 0.016 15.3 9.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX89613.1 - 0.0059 16.6 8.1 0.014 15.4 8.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YrhK PF14145.6 ORX89613.1 - 0.2 11.6 2.9 0.91 9.4 2.9 1.9 1 1 0 1 1 1 0 YrhK-like protein FANCL_C PF11793.8 ORX89613.1 - 0.36 11.0 11.4 2.3 8.5 11.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain S1FA PF04689.13 ORX89613.1 - 0.47 10.6 0.1 0.47 10.6 0.1 1.8 1 1 1 2 2 2 0 DNA binding protein S1FA Jiraiya PF15038.6 ORX89613.1 - 1.9 7.9 6.8 2.4 7.5 6.8 1.5 1 1 0 1 1 1 0 Jiraiya zf-RING-like PF08746.11 ORX89613.1 - 2.7 8.4 10.1 5.6 7.4 10.1 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 ORX89613.1 - 4.4 7.3 16.5 0.13 12.2 8.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORX89613.1 - 6.5 6.5 14.3 0.84 9.3 8.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RNA_pol_Rpb2_6 PF00562.28 ORX89614.1 - 2.3e-129 431.9 0.5 1.3e-128 429.4 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORX89614.1 - 4.1e-71 238.7 0.0 6.3e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ORX89614.1 - 3.3e-49 167.1 0.2 1.6e-48 164.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORX89614.1 - 1.2e-34 118.5 0.2 3.2e-34 117.2 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ORX89614.1 - 1.4e-25 89.2 0.4 4e-25 87.8 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 ORX89614.1 - 7.3e-24 83.8 3.4 7.5e-24 83.8 2.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 ORX89614.1 - 1.3e-21 76.9 0.4 4.5e-21 75.2 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_POL_M_15KD PF02150.16 ORX89614.1 - 0.17 11.8 0.9 0.55 10.2 0.9 1.9 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit PPR_2 PF13041.6 ORX89615.1 - 3.6e-202 654.6 58.4 2.1e-17 63.1 0.7 22.1 7 2 17 24 24 23 20 PPR repeat family PPR_1 PF12854.7 ORX89615.1 - 8.2e-132 428.5 23.3 2.5e-10 39.9 0.1 22.1 22 0 0 22 22 22 19 PPR repeat PPR PF01535.20 ORX89615.1 - 5e-131 418.2 39.2 2e-07 30.8 0.1 22.6 22 0 0 22 22 22 21 PPR repeat PPR_3 PF13812.6 ORX89615.1 - 8.7e-109 355.6 38.1 3e-12 46.4 0.5 15.7 9 5 9 18 18 18 14 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX89615.1 - 1.3e-63 214.2 8.8 1.5e-09 37.5 0.1 9.1 3 2 7 10 10 10 7 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORX89615.1 - 1.2e-14 54.1 10.0 0.00044 19.2 0.0 6.3 3 2 3 6 6 6 3 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 ORX89615.1 - 6.7e-11 42.6 34.5 0.051 14.0 0.2 11.8 4 3 8 12 12 12 4 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 ORX89615.1 - 1.1e-10 41.8 0.1 7.3 7.2 0.1 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat ATP13 PF12921.7 ORX89615.1 - 3.1e-08 33.5 9.4 0.0048 16.7 0.0 8.5 5 3 6 11 11 11 1 Mitochondrial ATPase expression TPR_14 PF13428.6 ORX89615.1 - 1.1e-06 29.0 0.0 3.6 8.6 0.0 8.5 8 4 4 12 12 8 1 Tetratricopeptide repeat Prp18 PF02840.15 ORX89615.1 - 1.6e-05 24.9 8.8 0.2 11.7 0.0 5.5 5 0 0 5 5 5 2 Prp18 domain ECSIT PF06239.11 ORX89615.1 - 0.00012 21.3 7.6 9 5.3 0.1 7.6 3 3 5 9 9 9 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_MalT PF17874.1 ORX89615.1 - 0.0094 15.4 2.9 6.1 6.1 0.0 5.0 4 1 1 6 6 6 1 MalT-like TPR region ATC_hydrolase PF14196.6 ORX89615.1 - 0.034 14.9 0.3 37 5.1 0.0 4.4 4 1 0 4 4 4 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Microtub_bd PF16796.5 ORX89615.1 - 0.052 13.5 0.2 3.3 7.6 0.0 2.9 2 0 0 2 2 2 0 Microtubule binding Clathrin PF00637.20 ORX89615.1 - 0.073 12.9 20.1 5.5 6.9 0.2 7.9 4 3 3 9 9 9 0 Region in Clathrin and VPS Inhibitor_I9 PF05922.16 ORX89615.1 - 0.2 12.3 0.8 21 5.9 0.0 4.0 4 1 0 4 4 2 0 Peptidase inhibitor I9 SNAP PF14938.6 ORX89615.1 - 0.95 8.8 6.2 11 5.3 0.0 5.2 6 2 0 7 7 7 0 Soluble NSF attachment protein, SNAP Cyt-b5 PF00173.28 ORX89616.1 - 2.8e-11 43.4 0.0 3.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AhpC-TSA PF00578.21 ORX89617.1 - 1.9e-25 89.2 0.0 2.3e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX89617.1 - 8.2e-16 58.0 0.0 8.5e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin Ras PF00071.22 ORX89618.1 - 5.6e-58 195.1 1.5 6.6e-58 194.9 1.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89618.1 - 7e-34 116.6 0.3 1.3e-33 115.8 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89618.1 - 3.6e-19 68.9 0.4 4.7e-19 68.5 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX89618.1 - 1.1e-08 35.2 0.1 7.6e-08 32.4 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX89618.1 - 5.3e-07 29.2 0.3 6.2e-07 29.0 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX89618.1 - 6.5e-07 29.1 0.3 1.2e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORX89618.1 - 0.00037 20.0 0.3 0.00081 18.9 0.1 1.6 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORX89618.1 - 0.00095 19.1 0.7 0.44 10.4 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 ORX89618.1 - 0.014 14.6 2.4 1.1 8.3 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 ORX89618.1 - 0.022 14.3 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 ORX89618.1 - 0.028 13.7 0.2 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 ORX89618.1 - 0.031 14.0 1.3 0.049 13.4 1.3 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ORX89618.1 - 0.034 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 ORX89618.1 - 0.064 13.3 0.3 0.14 12.2 0.3 1.9 1 1 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 ORX89618.1 - 0.077 13.4 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Aa_trans PF01490.18 ORX89619.1 - 2.4e-79 266.9 36.5 2.9e-79 266.7 36.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-C2H2 PF00096.26 ORX89620.1 - 1.1e-14 53.9 19.6 3.3e-06 27.3 2.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89620.1 - 5.3e-13 48.8 10.6 2.2e-07 31.0 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89620.1 - 3.4e-11 43.0 16.8 1.4e-05 25.5 1.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX89620.1 - 0.00032 20.9 4.7 0.68 10.3 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.6 ORX89620.1 - 0.0013 18.6 0.8 0.98 9.4 0.2 2.3 2 0 0 2 2 2 2 Probable zinc-ribbon domain zf_ZIC PF18366.1 ORX89620.1 - 0.0039 17.3 1.4 2.2 8.5 0.1 2.3 1 1 1 2 2 2 2 Zic proteins zinc finger domain zf-RING_7 PF02591.15 ORX89620.1 - 0.0065 16.6 0.7 1.7 8.9 0.1 2.3 2 0 0 2 2 2 1 C4-type zinc ribbon domain zf-C2H2_8 PF15909.5 ORX89620.1 - 0.0069 16.7 5.4 0.03 14.6 2.6 2.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon DUF3268 PF11672.8 ORX89620.1 - 0.012 15.9 0.6 0.012 15.9 0.6 1.4 2 0 0 2 2 1 0 zinc-finger-containing domain zf-CSL PF05207.13 ORX89620.1 - 0.018 14.7 0.2 0.031 14.0 0.2 1.4 1 0 0 1 1 1 0 CSL zinc finger Ephrin_rec_like PF07699.13 ORX89620.1 - 0.029 14.1 3.4 0.18 11.6 0.5 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like PyrI_C PF02748.15 ORX89620.1 - 0.039 13.9 1.3 0.16 11.9 0.1 2.2 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 ORX89620.1 - 0.067 13.0 6.5 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 ORX89620.1 - 0.082 13.3 5.1 7.8 7.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORX89620.1 - 0.098 12.8 7.7 0.3 11.2 3.6 2.4 1 1 2 3 3 3 0 Zinc ribbon domain zf-CHCC PF10276.9 ORX89620.1 - 0.14 12.2 5.0 0.19 11.8 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger domain zinc_ribbon_2 PF13240.6 ORX89620.1 - 0.2 11.4 4.6 0.35 10.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_3rep PF18868.1 ORX89620.1 - 0.23 12.2 3.4 3.9 8.2 0.5 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Mss51 PF13824.6 ORX89620.1 - 0.23 11.6 9.7 1.1 9.4 0.4 2.6 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_UBZ PF18439.1 ORX89620.1 - 0.23 11.1 4.3 3.6 7.2 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 ORX89620.1 - 0.26 11.5 12.9 12 6.1 7.2 3.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 ORX89620.1 - 0.38 10.7 9.9 0.49 10.4 1.3 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 ORX89620.1 - 0.54 10.4 0.1 0.54 10.4 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.12 ORX89620.1 - 0.6 10.4 5.4 1.9 8.8 3.1 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain HNH PF01844.23 ORX89620.1 - 0.74 10.0 0.2 0.74 10.0 0.2 2.8 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_6 PF13912.6 ORX89620.1 - 5.4 7.1 15.3 2.7 8.1 2.5 3.3 3 1 0 3 3 3 0 C2H2-type zinc finger Aminotran_4 PF01063.19 ORX89621.1 - 3.4e-27 95.8 0.0 4.1e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Aa_trans PF01490.18 ORX89622.1 - 1.7e-69 234.5 42.5 1.9e-69 234.3 42.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORX89622.1 - 0.0032 16.4 49.3 0.01 14.7 49.3 1.7 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 ORX89623.1 - 1.1e-68 231.8 37.9 1.3e-68 231.6 37.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX89623.1 - 0.00012 21.1 19.4 0.00012 21.1 19.4 2.7 2 1 0 2 2 2 1 Spore germination protein AA_permease_2 PF13520.6 ORX89623.1 - 0.0094 14.8 46.5 0.07 11.9 46.5 2.2 1 1 0 1 1 1 1 Amino acid permease Tropomyosin_1 PF12718.7 ORX89624.1 - 2.1e-57 193.3 69.4 1.2e-33 116.3 32.1 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 ORX89624.1 - 5.2e-20 71.8 65.5 7.2e-11 41.9 51.5 4.3 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.6 ORX89624.1 - 6.7e-07 28.9 54.4 0.0036 16.7 13.5 3.4 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 ORX89624.1 - 4.3e-05 23.6 41.6 0.12 12.4 10.7 4.4 1 1 3 4 4 4 2 Laminin Domain II UPF0242 PF06785.11 ORX89624.1 - 7.5e-05 22.9 20.5 7.5e-05 22.9 20.5 3.3 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus CCDC144C PF14915.6 ORX89624.1 - 0.00054 19.2 49.0 0.00054 19.2 49.0 2.5 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region KELK PF15796.5 ORX89624.1 - 0.003 18.0 11.2 0.003 18.0 11.2 5.3 3 1 3 6 6 4 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Uso1_p115_C PF04871.13 ORX89624.1 - 0.014 15.8 67.3 0.15 12.4 19.9 4.0 2 2 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_I PF06008.14 ORX89624.1 - 0.021 14.5 10.8 0.021 14.5 10.8 3.7 1 1 1 3 3 3 0 Laminin Domain I DHR10 PF18595.1 ORX89624.1 - 0.025 14.7 66.1 0.4 10.7 19.0 4.4 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain COG2 PF06148.11 ORX89624.1 - 0.025 14.7 5.6 0.025 14.7 5.6 5.3 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.8 ORX89624.1 - 0.026 14.5 7.7 0.026 14.5 7.7 5.5 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 ORX89624.1 - 0.049 13.7 34.6 0.058 13.4 5.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) SlyX PF04102.12 ORX89624.1 - 0.055 14.1 4.0 0.055 14.1 4.0 5.9 1 1 5 6 6 6 0 SlyX DUF4201 PF13870.6 ORX89624.1 - 0.084 12.6 54.3 0.033 13.9 22.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) BORCS7 PF16088.5 ORX89624.1 - 0.17 12.1 17.5 0.34 11.2 1.7 3.6 2 2 0 3 3 3 0 BLOC-1-related complex sub-unit 7 EzrA PF06160.12 ORX89624.1 - 0.19 9.9 51.9 0.015 13.5 15.2 2.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 ORX89624.1 - 0.34 11.1 62.9 2.4 8.3 25.7 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) T3SSipB PF16535.5 ORX89624.1 - 0.49 10.9 39.6 3 8.3 5.6 3.4 1 1 2 3 3 3 0 Type III cell invasion protein SipB Alanine_zipper PF11839.8 ORX89624.1 - 0.81 10.1 24.7 1.7 9.0 4.0 4.8 5 1 0 5 5 4 0 Alanine-zipper, major outer membrane lipoprotein Taxilin PF09728.9 ORX89624.1 - 1.6 7.8 56.7 0.12 11.5 2.2 3.8 1 1 0 2 2 1 0 Myosin-like coiled-coil protein Jnk-SapK_ap_N PF09744.9 ORX89624.1 - 1.9 8.7 62.6 2.3 8.4 27.5 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 ORX89624.1 - 2.5 7.9 50.5 0.91 9.3 14.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) ERM PF00769.19 ORX89624.1 - 2.7 7.8 67.6 1.1 9.0 27.1 3.2 1 1 2 3 3 3 0 Ezrin/radixin/moesin family XhlA PF10779.9 ORX89624.1 - 2.7 8.2 60.1 0.17 12.1 8.8 6.4 3 1 3 6 6 6 0 Haemolysin XhlA Spc7 PF08317.11 ORX89624.1 - 4.6 6.0 63.0 1.1 8.0 27.2 3.1 1 1 1 2 2 2 0 Spc7 kinetochore protein MscS_porin PF12795.7 ORX89624.1 - 5.2 6.5 54.6 14 5.1 14.4 2.8 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain PspA_IM30 PF04012.12 ORX89624.1 - 5.3 6.6 51.6 5.2 6.6 2.7 4.5 1 1 2 3 3 3 0 PspA/IM30 family APG6_N PF17675.1 ORX89624.1 - 5.3 7.6 71.0 3.8 8.0 28.2 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region AAA_13 PF13166.6 ORX89624.1 - 6.1 5.3 47.7 0.28 9.8 16.7 2.4 1 1 0 2 2 2 0 AAA domain DUF3450 PF11932.8 ORX89624.1 - 6.3 6.0 49.3 0.067 12.5 15.9 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) PI3K_P85_iSH2 PF16454.5 ORX89624.1 - 6.9 6.2 48.6 6.2 6.4 15.5 3.3 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 ORX89624.1 - 7 5.9 45.5 1.1 8.5 10.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 ORX89624.1 - 7.4 6.4 31.9 0.15 11.9 7.4 3.9 2 2 1 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 ORX89624.1 - 8 6.6 38.4 2.8 8.1 8.4 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 ORX89624.1 - 8.4 6.8 68.3 8.1 6.9 2.3 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 ORX89624.1 - 8.9 3.7 53.7 1.3 6.5 20.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Phage_holin_6_1 PF09682.10 ORX89624.1 - 9.3 6.7 19.3 0.15 12.5 1.4 3.4 3 2 0 3 3 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) COBRA1 PF06209.13 ORX89625.1 - 5.2e-85 286.1 4.6 7.1e-85 285.7 4.6 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) SRI PF08236.11 ORX89625.1 - 0.66 10.2 4.7 0.55 10.4 1.5 2.5 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Histone_H2A_C PF16211.5 ORX89626.1 - 4.6e-20 71.1 2.3 8.3e-20 70.2 2.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORX89626.1 - 1.8e-16 60.7 0.0 2.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORX89626.1 - 2.8e-05 24.3 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HIT PF01230.23 ORX89627.1 - 1.1e-24 87.0 0.2 1.4e-24 86.7 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORX89627.1 - 2e-10 41.1 0.1 2.8e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORX89627.1 - 6.3e-07 29.3 0.1 8.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MFS_1 PF07690.16 ORX89629.1 - 1.1e-45 156.1 24.4 1.7e-45 155.5 24.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX89629.1 - 4.6e-12 45.5 15.7 2.2e-05 23.5 2.0 3.2 1 1 2 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 ORX89629.1 - 2.3e-11 43.6 2.0 4.8e-11 42.6 2.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX89629.1 - 2.4e-08 32.9 12.9 1.4e-05 23.8 5.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 ORX89629.1 - 3.2e-06 25.8 14.3 3.6e-06 25.7 5.8 2.8 2 1 1 3 3 3 2 Transmembrane secretion effector OATP PF03137.20 ORX89629.1 - 0.01 14.1 17.8 0.36 9.1 0.2 3.6 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF485 PF04341.12 ORX89629.1 - 0.019 14.9 12.5 0.22 11.5 0.6 3.6 4 1 0 4 4 4 0 Protein of unknown function, DUF485 dCMP_cyt_deam_1 PF00383.23 ORX89630.1 - 6.5e-19 67.7 0.4 7.9e-19 67.4 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX89630.1 - 1.3e-18 67.1 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ORX89630.1 - 0.012 15.7 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 ORX89630.1 - 0.079 13.1 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC3 E1-E2_ATPase PF00122.20 ORX89631.1 - 9.9e-40 136.0 0.7 9.9e-40 136.0 0.7 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX89631.1 - 1.1e-23 83.8 4.0 1.1e-23 83.8 4.0 2.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX89631.1 - 2.3e-22 78.9 0.0 5.4e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX89631.1 - 3.1e-20 73.4 0.0 2e-19 70.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX89631.1 - 3.8e-12 45.7 0.1 3.8e-12 45.7 0.1 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Borrelia_P13 PF05628.12 ORX89631.1 - 0.0004 20.4 0.4 0.002 18.1 0.0 2.3 2 0 0 2 2 2 1 Borrelia membrane protein P13 Hydrolase_3 PF08282.12 ORX89631.1 - 0.0021 17.8 3.2 0.0027 17.5 0.6 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX89631.1 - 0.033 14.6 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Orf78 PF06024.12 ORX89631.1 - 1.1 9.6 3.8 34 4.8 0.2 3.3 3 0 0 3 3 3 0 Orf78 (ac78) AMP-binding PF00501.28 ORX89632.1 - 3e-92 309.4 0.0 5.4e-92 308.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 ORX89632.1 - 2.2e-09 36.7 2.4 0.64 9.8 0.0 5.9 5 0 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 ORX89632.1 - 8.4e-06 26.7 0.0 1.8e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX89632.1 - 0.00018 21.8 0.0 0.00044 20.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 ORX89632.1 - 0.0091 15.7 4.3 6.9 6.5 0.0 5.2 4 1 1 5 5 5 1 Hexapeptide repeat of succinyl-transferase DJ-1_PfpI PF01965.24 ORX89635.1 - 7.3e-09 35.6 0.0 2.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX89635.1 - 0.0016 18.2 0.1 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX89635.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX89641.1 - 5.2e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX89641.1 - 0.00072 19.3 0.0 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX89641.1 - 0.0024 17.6 0.0 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX89642.1 - 2.8e-08 33.8 0.0 1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX89642.1 - 0.0011 18.6 0.1 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX89642.1 - 0.0032 17.2 0.0 0.0074 16.0 0.0 1.6 1 1 0 1 1 1 1 Latrotoxin C-terminal domain Abhydrolase_3 PF07859.13 ORX89643.1 - 1.5e-54 185.1 0.0 2.1e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX89643.1 - 1.4e-07 30.7 0.0 6.7e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ORX89643.1 - 0.00029 20.4 0.0 0.088 12.4 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 ORX89643.1 - 0.0037 16.0 0.0 0.049 12.3 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 ORX89643.1 - 0.01 15.3 0.0 0.038 13.5 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORX89643.1 - 0.05 14.2 0.4 0.17 12.5 0.1 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 ORX89643.1 - 0.12 12.1 0.0 11 5.6 0.0 2.5 3 0 0 3 3 3 0 Putative esterase Peptidase_S15 PF02129.18 ORX89643.1 - 0.15 11.6 0.0 1.4 8.4 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) VCBS PF13517.6 ORX89644.1 - 0.0014 19.2 0.1 0.46 11.1 0.3 3.4 2 1 1 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TLP-20 PF06088.11 ORX89644.1 - 0.035 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FG-GAP PF01839.23 ORX89644.1 - 0.037 14.2 0.7 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 FG-GAP repeat MAPKK1_Int PF08923.10 ORX89644.1 - 0.17 11.7 0.2 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting G6PD_C PF02781.16 ORX89645.1 - 1.8e-114 381.8 0.0 2.5e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORX89645.1 - 4.3e-59 200.1 0.2 6.5e-59 199.5 0.2 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 ORX89646.1 - 2.6e-12 46.5 17.1 1.7e-06 28.2 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89646.1 - 1.7e-10 40.8 1.2 1.7e-10 40.8 1.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89646.1 - 1.7e-09 37.7 12.5 0.00016 22.2 0.6 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX89646.1 - 2.7e-05 24.1 7.5 0.00079 19.4 0.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 ORX89646.1 - 0.00041 20.3 8.9 0.025 14.6 1.2 2.1 1 1 1 2 2 2 2 BED zinc finger PyrI_C PF02748.15 ORX89646.1 - 0.0017 18.2 5.1 0.035 14.0 0.5 2.1 1 1 1 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 ORX89646.1 - 0.003 17.8 8.9 0.03 14.6 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORX89646.1 - 0.0031 17.4 0.2 0.0031 17.4 0.2 2.5 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-CHCC PF10276.9 ORX89646.1 - 0.0054 16.8 2.4 1.1 9.3 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger domain zf-MYST PF17772.1 ORX89646.1 - 0.0067 16.0 7.7 0.089 12.4 1.7 2.1 1 1 1 2 2 2 2 MYST family zinc finger domain zf-C2H2_2 PF12756.7 ORX89646.1 - 0.0084 16.4 6.4 0.64 10.4 0.2 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 ORX89646.1 - 0.0085 16.2 1.7 0.39 10.9 0.2 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 ORX89646.1 - 0.013 15.2 9.2 0.24 11.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 ORX89646.1 - 0.026 15.0 7.5 0.091 13.2 0.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2180 PF09947.9 ORX89646.1 - 0.036 14.1 2.8 0.46 10.5 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-H2C2_5 PF13909.6 ORX89646.1 - 0.069 12.9 21.0 0.73 9.6 3.4 3.2 2 1 1 3 3 3 0 C2H2-type zinc-finger domain C5HCH PF17982.1 ORX89646.1 - 0.12 12.6 7.1 0.52 10.5 1.5 2.2 1 1 1 2 2 2 0 NSD Cys-His rich domain DUF4764 PF15961.5 ORX89646.1 - 0.41 9.3 4.1 2.7 6.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-AN1 PF01428.16 ORX89646.1 - 8.4 6.6 15.5 3 8.1 2.6 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Aldo_ket_red PF00248.21 ORX89647.1 - 9.2e-76 254.8 0.0 1.1e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 ORX89648.1 - 5.2e-10 39.3 20.0 9.1e-07 29.0 6.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX89648.1 - 9.5e-09 35.3 14.9 7.5e-05 23.0 3.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89648.1 - 8.9e-06 26.1 12.3 0.0078 17.0 2.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX89648.1 - 0.017 15.4 0.9 0.033 14.5 0.9 1.5 1 1 0 1 1 1 0 C2H2-type zinc ribbon DUF2225 PF09986.9 ORX89648.1 - 0.025 14.3 1.0 0.027 14.2 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-LYAR PF08790.11 ORX89648.1 - 0.036 14.0 0.8 2.1 8.3 0.0 2.4 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 ORX89648.1 - 0.05 13.7 4.4 0.11 12.6 0.4 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain UBZ_FAAP20 PF15750.5 ORX89648.1 - 0.096 12.6 0.7 0.24 11.4 0.2 1.8 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C2H2_6 PF13912.6 ORX89648.1 - 0.19 11.7 9.2 0.53 10.4 0.3 3.2 2 2 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_46 PF01374.18 ORX89649.1 - 1.7e-29 103.0 0.1 1.9e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 DcpS_C PF11969.8 ORX89651.1 - 1.3e-17 64.3 0.0 1.6e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORX89651.1 - 3.7e-08 34.0 0.0 5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 ORX89651.1 - 0.0014 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Paf67 PF10255.9 ORX89652.1 - 6.2e-176 585.3 6.6 6.2e-176 585.3 6.6 1.3 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ORX89652.1 - 0.0042 17.1 0.0 0.041 14.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89652.1 - 0.017 14.9 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 ORX89652.1 - 0.074 13.0 2.6 3.5 7.6 0.0 2.7 3 0 0 3 3 3 0 CSN8/PSMD8/EIF3K family TPR_12 PF13424.6 ORX89652.1 - 0.11 12.7 0.0 0.8 10.0 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat SRP-alpha_N PF04086.13 ORX89652.1 - 0.2 11.5 1.0 3.7 7.4 0.3 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal V-ATPase_C PF03223.15 ORX89653.1 - 3.1e-138 461.2 5.4 3.4e-138 461.1 5.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C EAR PF07897.11 ORX89653.1 - 0.095 12.3 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression ATP-synt_S1 PF05827.12 ORX89654.1 - 8.9e-09 35.3 0.2 1.8e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) UCH PF00443.29 ORX89655.1 - 2.2e-34 119.1 1.2 4.7e-34 118.0 1.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX89655.1 - 1.2e-13 51.4 23.4 1.2e-13 51.4 23.4 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORX89655.1 - 2.9e-07 30.1 0.1 8.1e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 ORX89655.1 - 3.1e-06 27.7 0.0 0.002 18.7 0.0 3.1 2 0 0 2 2 2 1 DUSP domain Rad60-SLD PF11976.8 ORX89655.1 - 0.00083 19.1 0.4 0.02 14.7 0.1 2.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORX89655.1 - 0.11 13.0 0.1 0.32 11.5 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Pannexin_like PF12534.8 ORX89655.1 - 8.4 5.4 9.6 0.15 11.1 2.1 1.9 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 RRM_1 PF00076.22 ORX89656.1 - 9.9e-14 50.9 0.0 1.9e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 ORX89657.1 - 6.6e-97 321.0 0.0 4.9e-47 159.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX89657.1 - 1.3e-27 95.3 6.3 6.1e-14 51.6 0.3 3.2 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 ORX89657.1 - 1.6e-19 69.9 0.5 7.8e-19 67.6 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ORX89657.1 - 3e-14 53.0 0.0 7.7e-06 25.7 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX89657.1 - 1.6e-13 51.1 0.0 1.7e-07 31.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 ORX89657.1 - 8e-12 44.8 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 ORX89657.1 - 3.3e-11 43.9 0.2 0.00045 20.6 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 ORX89657.1 - 3.5e-11 43.4 0.0 1.9e-05 24.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORX89657.1 - 6e-11 42.5 0.2 3.7e-05 23.8 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX89657.1 - 1e-08 35.5 0.1 0.061 13.6 0.0 4.0 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORX89657.1 - 1.6e-08 34.2 0.1 0.0017 17.6 0.0 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 ORX89657.1 - 8.2e-08 32.6 0.0 0.0051 17.2 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 ORX89657.1 - 2.1e-07 30.6 0.2 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORX89657.1 - 3.9e-07 30.2 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 ORX89657.1 - 4.6e-07 29.7 0.2 7.1e-06 25.9 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 ORX89657.1 - 5.4e-07 30.2 0.0 0.031 14.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ORX89657.1 - 9.9e-07 29.3 0.0 0.0068 16.9 0.0 3.9 3 1 0 3 3 2 1 ABC transporter IstB_IS21 PF01695.17 ORX89657.1 - 1.9e-06 27.7 0.0 0.062 13.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 ORX89657.1 - 9.3e-06 24.9 0.1 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 ORX89657.1 - 1.1e-05 25.0 0.0 0.064 12.8 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 ORX89657.1 - 1.2e-05 24.8 0.2 0.51 9.6 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 ORX89657.1 - 1.3e-05 25.5 0.1 0.16 12.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_25 PF13481.6 ORX89657.1 - 2.9e-05 23.7 2.4 1.6 8.2 0.0 3.6 2 2 2 4 4 3 2 AAA domain ATPase_2 PF01637.18 ORX89657.1 - 3.6e-05 23.8 0.4 0.26 11.2 0.0 3.4 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 ORX89657.1 - 4.8e-05 23.3 0.0 0.27 11.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 ORX89657.1 - 4.8e-05 23.2 0.0 0.12 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORX89657.1 - 7.5e-05 22.6 0.0 0.0065 16.2 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 ORX89657.1 - 8.2e-05 21.9 0.0 0.039 13.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 ORX89657.1 - 9.3e-05 22.2 0.0 0.63 9.7 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 ORX89657.1 - 0.00013 21.9 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 ORX89657.1 - 0.00014 22.3 2.3 0.55 10.7 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_3 PF07726.11 ORX89657.1 - 0.00045 20.1 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX89657.1 - 0.0007 19.6 0.2 0.3 11.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain PhoH PF02562.16 ORX89657.1 - 0.00071 19.1 0.2 1.1 8.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.12 ORX89657.1 - 0.00073 18.9 0.0 0.52 9.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 ORX89657.1 - 0.00078 19.5 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 ORX89657.1 - 0.0011 18.3 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.6 ORX89657.1 - 0.0013 18.6 0.4 1.4 8.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 ORX89657.1 - 0.003 16.9 0.1 1.4 8.1 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 ORX89657.1 - 0.0092 15.9 0.0 0.88 9.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 ORX89657.1 - 0.0095 16.3 0.7 13 6.1 0.0 3.5 3 1 1 4 4 3 0 AAA domain Sigma54_activ_2 PF14532.6 ORX89657.1 - 0.0096 16.0 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 ORX89657.1 - 0.02 14.6 0.1 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX89657.1 - 0.02 14.8 1.5 5 7.0 0.0 4.2 4 1 1 5 5 4 0 NTPase Cytidylate_kin2 PF13189.6 ORX89657.1 - 0.035 14.3 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase-like family Molydop_binding PF01568.21 ORX89657.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Zot PF05707.12 ORX89657.1 - 0.16 11.6 0.0 2.6 7.6 0.0 2.6 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) Hydin_ADK PF17213.3 ORX89657.1 - 0.31 11.3 1.0 1.3e+02 2.7 0.0 3.8 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain SKI PF01202.22 ORX89657.1 - 0.34 11.0 1.8 9.4 6.3 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase CAP PF00188.26 ORX89658.1 - 1.4e-11 45.3 0.4 1.9e-11 44.9 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Aminotran_1_2 PF00155.21 ORX89659.1 - 1.9e-38 132.6 0.0 3.3e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX89659.1 - 0.0022 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase PRANC PF09372.10 ORX89659.1 - 0.18 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 PRANC domain PDZ_1 PF12812.7 ORX89660.1 - 7.1e-49 163.7 0.0 1.1e-32 111.8 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORX89660.1 - 5.3e-22 79.3 1.8 2.4e-19 70.7 0.1 3.0 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ORX89660.1 - 1.6e-14 53.5 0.0 0.0011 18.7 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORX89660.1 - 4.9e-09 36.4 0.0 0.029 14.7 0.0 4.0 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 ORX89660.1 - 3.8e-07 30.3 0.0 0.34 11.3 0.0 4.0 4 0 0 4 4 4 3 PDZ domain Tricorn_PDZ PF14685.6 ORX89660.1 - 0.0077 16.2 0.1 1.8 8.6 0.0 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.26 ORX89660.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Trypsin Peptidase_S46 PF10459.9 ORX89660.1 - 0.17 10.5 0.1 1.3 7.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 ORX89660.1 - 0.26 10.8 0.1 0.41 10.1 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Nop PF01798.18 ORX89661.1 - 2.3e-85 285.7 0.3 2.3e-85 285.7 0.3 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORX89661.1 - 4e-22 78.4 0.7 4e-22 78.4 0.7 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 ORX89661.1 - 0.00017 21.7 29.2 0.00046 20.4 29.2 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 ORC6 PF05460.13 ORX89661.1 - 0.48 9.6 20.7 0.8 8.9 20.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RR_TM4-6 PF06459.12 ORX89661.1 - 5.6 6.7 21.6 11 5.7 21.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L37ae PF01780.19 ORX89662.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORX89662.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORX89662.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORX89662.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORX89662.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain PAS_3 PF08447.12 ORX89663.1 - 9.2e-17 61.1 0.0 3e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORX89663.1 - 5.6e-10 39.4 0.0 4.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORX89663.1 - 2.4e-08 33.9 0.0 0.00087 19.3 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORX89663.1 - 1.9e-05 24.9 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 ORX89663.1 - 0.00036 21.2 0.0 0.044 14.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ORX89663.1 - 0.09 12.8 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 PAS domain Ribosomal_S7 PF00177.21 ORX89664.1 - 1.7e-33 115.4 0.4 1.9e-33 115.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S14 PF00253.21 ORX89665.1 - 3.8e-15 55.4 4.2 4.2e-15 55.2 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ORX89665.1 - 0.028 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) bZIP_1 PF00170.21 ORX89666.1 - 1.7e-12 47.2 14.8 2.6e-12 46.6 14.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX89666.1 - 2.7e-07 30.6 11.9 4.3e-07 29.9 11.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX89666.1 - 0.0027 18.2 7.7 0.0027 18.2 7.7 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ORX89666.1 - 0.096 12.0 4.6 0.16 11.3 4.6 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FAM76 PF16046.5 ORX89666.1 - 0.18 11.1 10.4 0.25 10.7 10.4 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4663 PF15668.5 ORX89666.1 - 0.38 9.8 7.8 0.5 9.4 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) CDC45 PF02724.14 ORX89666.1 - 0.98 7.6 11.9 1.3 7.3 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF334 PF03904.13 ORX89666.1 - 2.5 7.6 8.0 3.4 7.1 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) SID-1_RNA_chan PF13965.6 ORX89666.1 - 9.4 4.5 5.6 12 4.2 5.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CBS PF00571.28 ORX89667.1 - 2.3e-24 85.6 4.5 8.5e-11 42.1 0.3 4.5 5 0 0 5 5 5 4 CBS domain UCR_hinge PF02320.16 ORX89668.1 - 3.1e-25 88.1 6.4 3.1e-25 88.1 6.4 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein MMR1 PF08505.10 ORX89668.1 - 0.023 15.0 1.6 0.024 14.9 1.6 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CAS_C PF12026.8 ORX89668.1 - 0.053 13.6 0.7 0.065 13.3 0.7 1.0 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain TraF PF13728.6 ORX89668.1 - 0.13 12.1 1.6 0.16 11.7 1.6 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2052 PF09747.9 ORX89668.1 - 0.27 11.3 9.6 0.29 11.2 9.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 ORX89668.1 - 0.41 10.4 7.0 0.48 10.2 7.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 ORX89668.1 - 0.8 8.9 6.2 0.82 8.8 6.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.12 ORX89668.1 - 0.98 8.3 11.5 1.1 8.1 11.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein GOLD_2 PF13897.6 ORX89668.1 - 1.4 9.4 4.0 1.7 9.2 4.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking tRNA_bind_2 PF13725.6 ORX89668.1 - 2.8 7.6 5.2 3.3 7.4 5.2 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain PTPRCAP PF15713.5 ORX89668.1 - 4.2 7.7 13.5 5.2 7.4 13.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Dynamin_N PF00350.23 ORX89669.1 - 8e-45 152.9 0.1 1.9e-44 151.7 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORX89669.1 - 7e-19 68.1 1.9 1.4e-15 57.3 0.2 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 ORX89669.1 - 1.4e-06 28.4 0.1 1.1e-05 25.4 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 ORX89669.1 - 0.027 14.3 0.1 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORX89669.1 - 0.028 14.8 0.2 0.17 12.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 ORX89669.1 - 0.032 14.5 0.0 0.44 10.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 ORX89669.1 - 0.032 13.7 0.0 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORX89669.1 - 0.032 13.9 2.8 0.075 12.7 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain RraB PF06877.11 ORX89669.1 - 0.19 12.5 0.6 6.4 7.6 0.1 3.4 3 0 0 3 3 3 0 Regulator of ribonuclease activity B ABC_tran PF00005.27 ORX89669.1 - 0.27 11.7 1.0 2.3 8.7 0.0 2.9 4 0 0 4 4 4 0 ABC transporter RNA_pol_Rpb1_7 PF04990.12 ORX89670.1 - 9.9e-53 177.8 4.6 1.5e-52 177.1 4.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_5 PF04998.17 ORX89670.1 - 9.4e-30 103.9 0.1 1.1e-29 103.7 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 ORX89671.1 - 1.7e-89 300.3 0.0 3.3e-89 299.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 ORX89671.1 - 1.8e-78 262.5 0.9 3e-78 261.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 ORX89671.1 - 1.9e-71 239.9 0.1 4.3e-71 238.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 ORX89671.1 - 9.3e-52 175.1 0.0 3.2e-51 173.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 ORX89671.1 - 1.4e-44 152.6 0.0 2.7e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 ORX89671.1 - 2.2e-38 130.5 0.2 5.6e-38 129.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Romo1 PF10247.9 ORX89672.1 - 0.0096 16.3 0.3 0.02 15.3 0.3 1.4 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 IFRD_C PF04836.12 ORX89672.1 - 0.088 13.4 0.6 0.6 10.7 0.1 2.4 2 0 0 2 2 2 0 Interferon-related protein conserved region WD40 PF00400.32 ORX89673.1 - 7.5e-50 165.8 24.6 2.8e-09 37.4 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89673.1 - 7.4e-13 48.6 2.1 0.013 15.8 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX89673.1 - 1.5e-05 24.1 0.4 0.17 10.8 0.1 4.4 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORX89673.1 - 0.00055 19.9 0.1 0.11 12.4 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORX89673.1 - 0.0025 16.4 0.1 0.55 8.7 0.1 2.6 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 ORX89673.1 - 0.0072 15.0 10.8 0.028 13.1 0.2 4.9 5 2 1 6 6 6 1 Nucleoporin Nup120/160 PD40 PF07676.12 ORX89673.1 - 0.043 13.8 0.2 31 4.7 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat GPI-anchored PF10342.9 ORX89674.1 - 0.00087 20.0 0.0 0.0013 19.5 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Wzt_C PF14524.6 ORX89674.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Wzt C-terminal domain ATG16 PF08614.11 ORX89678.1 - 0.0044 17.3 7.3 0.0044 17.3 7.3 7.4 5 3 2 7 7 7 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 ORX89678.1 - 0.012 16.1 15.0 0.012 16.1 15.0 6.5 3 2 3 6 6 6 0 Fez1 ZapB PF06005.12 ORX89678.1 - 0.013 15.9 1.1 0.013 15.9 1.1 13.6 9 4 2 11 11 11 0 Cell division protein ZapB zf-C2H2 PF00096.26 ORX89679.1 - 2e-18 65.7 15.9 7.8e-07 29.2 0.2 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89679.1 - 3.4e-12 46.1 14.4 8.1e-05 23.1 0.2 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX89679.1 - 3.6e-10 39.8 22.2 5.5e-08 32.9 2.7 4.7 5 0 0 5 5 5 2 Zinc-finger double domain FOXP-CC PF16159.5 ORX89679.1 - 6e-06 26.8 7.6 0.87 10.3 0.3 4.0 1 1 3 4 4 4 4 FOXP coiled-coil domain zf_ZIC PF18366.1 ORX89679.1 - 0.00088 19.3 7.9 0.022 14.9 0.1 3.7 3 1 1 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 ORX89679.1 - 0.0017 18.5 6.1 0.12 12.5 0.5 2.8 1 1 2 3 3 3 2 Aberrant zinc-finger Ogr_Delta PF04606.12 ORX89679.1 - 0.014 15.3 0.3 0.22 11.5 0.0 2.4 1 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_8 PF15909.5 ORX89679.1 - 0.02 15.2 2.6 0.048 14.0 2.6 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORX89679.1 - 0.035 14.8 7.0 0.14 12.9 1.4 2.8 1 1 2 3 3 3 0 TRAF-type zinc finger zf-LYAR PF08790.11 ORX89679.1 - 0.04 13.8 0.2 0.93 9.5 0.0 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_Hakai PF18408.1 ORX89679.1 - 0.31 10.8 3.5 0.81 9.4 0.0 3.2 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 ORX89679.1 - 0.67 10.0 0.1 0.67 10.0 0.1 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 ORX89679.1 - 0.68 10.0 4.8 4.4 7.4 0.1 2.9 3 0 0 3 3 3 0 Zap1 zinc finger 2 zf-C2H2_jaz PF12171.8 ORX89679.1 - 0.7 10.3 8.6 3.6 8.0 0.0 3.8 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.27 ORX89680.1 - 3.5e-68 225.6 1.7 8.5e-23 80.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX89680.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Gammaproteobacterial serine protease ADH_N_2 PF16884.5 ORX89681.1 - 7.6e-26 90.1 0.0 1.6e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORX89681.1 - 6.4e-21 74.7 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX89681.1 - 8.6e-07 30.1 0.0 2e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 ORX89682.1 - 1.5e-51 175.3 0.0 1.7e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89682.1 - 1.1e-23 83.9 0.0 1.3e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX89682.1 - 2.9e-05 24.1 0.1 5.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX89682.1 - 0.012 14.6 0.1 0.016 14.1 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 ORX89682.1 - 0.024 14.3 0.1 1.5 8.4 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORX89682.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like zf-Tim10_DDP PF02953.15 ORX89691.1 - 5.7e-27 93.2 0.2 8.3e-27 92.6 0.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORX89691.1 - 0.059 13.1 1.8 0.12 12.1 1.8 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) GPI-anchored PF10342.9 ORX89692.1 - 0.0027 18.4 0.1 0.0046 17.7 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_7 PF17957.1 ORX89692.1 - 0.015 16.0 0.1 0.058 14.2 0.0 2.0 2 1 0 2 2 2 0 Bacterial Ig domain Levi_coat PF01819.17 ORX89692.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Levivirus coat protein Transglut_core PF01841.19 ORX89693.1 - 0.025 15.0 0.1 31 5.1 0.0 3.3 1 1 2 3 3 3 0 Transglutaminase-like superfamily GnsAB_toxin PF08178.11 ORX89693.1 - 0.028 14.3 11.8 5.3 7.1 0.2 4.9 2 1 3 5 5 5 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Ldt_C PF17969.1 ORX89693.1 - 0.036 14.8 1.1 21 5.9 0.0 3.3 2 1 1 3 3 3 0 L,D-transpeptidase C-terminal domain PKHD_C PF18331.1 ORX89693.1 - 0.069 13.2 0.2 34 4.6 0.0 4.1 2 1 1 4 4 4 0 PKHD-type hydroxylase C-terminal domain SpdB PF05122.13 ORX89693.1 - 0.11 12.6 34.3 10 6.3 0.1 8.8 1 1 9 10 10 10 0 Mobile element transfer protein DUF3139 PF11337.8 ORX89693.1 - 0.28 11.9 1.4 13 6.6 0.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Phage_TAC_4 PF08748.11 ORX89693.1 - 0.36 11.2 8.3 7.6 6.9 0.3 3.0 1 1 2 3 3 3 0 Phage tail assembly chaperone IL34 PF15036.6 ORX89693.1 - 0.74 9.8 3.5 4.1 7.4 1.5 2.7 1 1 2 3 3 3 0 Interleukin 34 DUF4391 PF14335.6 ORX89693.1 - 2 8.1 10.9 9 5.9 0.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4391) Spt5_N PF11942.8 ORX89693.1 - 2 9.4 12.7 1.3e+03 0.4 12.7 3.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Seryl_tRNA_N PF02403.22 ORX89693.1 - 6.1 7.1 11.2 13 6.1 5.4 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4112 PF13430.6 ORX89694.1 - 5.3e-21 74.9 1.9 5.8e-21 74.7 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PALP PF00291.25 ORX89695.1 - 2.9e-43 148.3 0.4 3.8e-43 148.0 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Phage_lysozyme PF00959.19 ORX89696.1 - 1.2e-12 48.2 0.1 1.6e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Phage lysozyme GHMP_kinases_C PF08544.13 ORX89699.1 - 0.015 15.6 0.0 5.3 7.5 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DUF4418 PF14387.6 ORX89699.1 - 0.12 12.6 1.3 3.9 7.7 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4418) Dynactin_p62 PF05502.13 ORX89699.1 - 3.1 6.5 9.3 2.2 6.9 1.0 2.3 1 1 1 2 2 2 0 Dynactin p62 family GHMP_kinases_C PF08544.13 ORX89700.1 - 0.16 12.4 0.0 14 6.1 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DUF4418 PF14387.6 ORX89700.1 - 0.34 11.1 2.0 6.3 7.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Dynactin_p62 PF05502.13 ORX89700.1 - 8.1 5.1 10.5 2.5 6.8 1.0 2.3 1 1 0 2 2 2 0 Dynactin p62 family PAD_porph PF04371.15 ORX89703.1 - 1.6e-107 359.5 0.0 1.8e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Gpr1_Fun34_YaaH PF01184.19 ORX89703.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Methyltransf_23 PF13489.6 ORX89704.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89704.1 - 2.9e-05 24.8 0.0 0.036 14.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 ORX89704.1 - 0.09 12.6 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORX89704.1 - 0.19 12.5 0.1 2.4 8.9 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORX89705.1 - 4.4e-05 23.4 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX89705.1 - 9.4e-05 23.1 0.0 0.07 13.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain DUF2236 PF09995.9 ORX89706.1 - 0.0069 16.6 0.2 0.0083 16.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Mago-bind PF09282.10 ORX89706.1 - 0.13 12.2 1.3 0.59 10.1 0.2 2.2 2 0 0 2 2 2 0 Mago binding Glyco_tran_28_C PF04101.16 ORX89708.1 - 0.07 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ank_5 PF13857.6 ORX89708.1 - 0.093 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pirin PF02678.16 ORX89709.1 - 8.7e-32 109.3 0.1 1.7e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORX89709.1 - 5.2e-28 97.5 0.0 9.8e-27 93.3 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORX89709.1 - 0.01 15.5 5.0 0.034 13.9 1.1 2.5 2 1 0 2 2 2 0 Cupin domain Polysacc_deac_1 PF01522.21 ORX89710.1 - 7.1e-29 100.2 0.0 2.4e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORX89710.1 - 0.015 15.0 1.3 0.024 14.3 1.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) FIVAR PF07554.13 ORX89710.1 - 0.033 14.9 0.7 0.24 12.2 0.0 2.3 2 0 0 2 2 2 0 FIVAR domain Thioredoxin_16 PF18569.1 ORX89710.1 - 0.049 13.7 0.3 0.13 12.4 0.3 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Nexin_C PF08628.12 ORX89711.1 - 1.9e-28 99.3 0.0 5.2e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 ORX89711.1 - 3.3e-17 62.8 1.4 2.7e-16 59.9 0.8 2.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain C2 PF00168.30 ORX89711.1 - 3.4e-11 43.3 0.0 8.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain PX PF00787.24 ORX89711.1 - 6.3e-11 42.3 0.1 2.2e-10 40.5 0.1 2.0 1 0 0 1 1 1 1 PX domain PXA PF02194.15 ORX89711.1 - 3.4e-10 40.2 1.1 1.2e-09 38.5 0.1 2.5 2 0 0 2 2 2 1 PXA domain DUF919 PF06034.11 ORX89711.1 - 1.1 9.2 3.7 12 5.8 0.2 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) IF-2B PF01008.17 ORX89712.1 - 1.9e-74 250.4 0.0 2.2e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF383 PF04063.14 ORX89712.1 - 0.049 13.3 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) PS_pyruv_trans PF04230.13 ORX89712.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase DeoRC PF00455.22 ORX89712.1 - 0.093 12.7 0.1 13 5.7 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Vps51 PF08700.11 ORX89712.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.8 1 1 0 1 1 1 0 Vps51/Vps67 Pkinase PF00069.25 ORX89714.1 - 5.2e-18 65.3 0.0 8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.11 ORX89714.1 - 0.019 14.1 0.2 0.047 12.7 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 ORX89714.1 - 0.059 13.3 0.1 0.46 10.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.20 ORX89714.1 - 0.081 12.2 0.3 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase PAS PF00989.25 ORX89714.1 - 0.12 12.4 0.4 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 PAS fold Isochorismatase PF00857.20 ORX89715.1 - 1.4e-25 90.5 0.0 1.6e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Amidohydro_1 PF01979.20 ORX89716.1 - 1.6e-81 274.3 0.0 1.9e-81 274.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX89716.1 - 4.8e-09 36.2 0.0 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Pkinase PF00069.25 ORX89717.1 - 1.6e-64 217.8 0.0 2.2e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89717.1 - 4.9e-32 111.2 0.0 6.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX89717.1 - 4.7e-07 29.4 0.0 7.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX89717.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX89717.1 - 0.0039 17.2 0.3 0.0067 16.4 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX89717.1 - 0.0083 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX89717.1 - 0.096 11.6 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 ORX89718.1 - 1.6e-64 217.9 0.0 2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89718.1 - 5.5e-32 111.1 0.0 7.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX89718.1 - 7.6e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX89718.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX89718.1 - 0.0033 17.4 0.3 0.0067 16.4 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX89718.1 - 0.0086 15.5 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX89718.1 - 0.093 11.7 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RRN3 PF05327.11 ORX89719.1 - 2.3e-174 581.1 7.5 3e-174 580.7 7.5 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 NES_C_h PF18208.1 ORX89719.1 - 0.033 14.5 0.2 0.097 13.0 0.2 1.8 1 1 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain SQS_PSY PF00494.19 ORX89719.1 - 0.14 11.7 0.0 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 Squalene/phytoene synthase FCH PF00611.23 ORX89721.1 - 5e-13 49.1 0.1 5e-13 49.1 0.1 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 ORX89721.1 - 1.6e-11 43.9 0.1 3.6e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX89721.1 - 4.7e-11 42.1 0.0 9.6e-11 41.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX89721.1 - 1.2e-10 40.9 0.0 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PI3K_P85_iSH2 PF16454.5 ORX89721.1 - 0.064 12.9 13.0 0.2 11.2 3.1 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ribosomal_L13e PF01294.18 ORX89722.1 - 9.7e-82 273.2 7.3 1.3e-81 272.7 7.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e CH PF00307.31 ORX89723.1 - 1.7e-15 57.1 0.0 2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORX89723.1 - 0.00043 20.1 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain G-alpha PF00503.20 ORX89723.1 - 0.0022 17.2 0.1 0.0023 17.1 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit CH_2 PF06294.11 ORX89723.1 - 0.065 13.4 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 CH-like domain in sperm protein APG6_N PF17675.1 ORX89725.1 - 0.01 16.4 0.0 0.01 16.4 0.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region PikAIV_N PF18605.1 ORX89725.1 - 0.8 9.3 5.3 0.36 10.5 0.4 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CBM9_1 PF06452.11 ORX89726.1 - 0.0018 18.2 0.1 0.021 14.7 0.0 2.6 3 1 0 3 3 3 1 Carbohydrate family 9 binding domain-like RGS PF00615.19 ORX89727.1 - 1.5e-12 47.8 1.8 2.4e-12 47.1 1.8 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX89727.1 - 0.0044 16.8 11.7 0.052 13.3 11.7 2.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RGS-like PF09128.11 ORX89727.1 - 0.053 13.2 0.2 0.084 12.6 0.2 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Ribosomal_L36 PF00444.18 ORX89728.1 - 1.8e-20 72.8 10.8 2.4e-20 72.5 10.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Stm1_N PF09598.10 ORX89729.1 - 9.4e-06 26.4 5.0 9.4e-06 26.4 5.0 3.1 2 1 0 2 2 2 1 Stm1 HABP4_PAI-RBP1 PF04774.15 ORX89729.1 - 0.00054 20.8 30.2 0.009 16.8 23.3 3.8 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family ToxN_toxin PF13958.6 ORX89729.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Toxin ToxN, type III toxin-antitoxin system GRP PF07172.11 ORX89729.1 - 0.87 10.3 18.5 0.44 11.3 3.0 3.2 2 1 1 3 3 3 0 Glycine rich protein family FXMRP1_C_core PF12235.8 ORX89729.1 - 3.8 8.1 23.1 2.5 8.8 1.1 2.5 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal Ribosomal_L13 PF00572.18 ORX89730.1 - 1.3e-10 41.6 0.1 9.2e-09 35.6 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Ribosomal_L7Ae PF01248.26 ORX89731.1 - 1.7e-24 85.3 0.0 2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family adh_short PF00106.25 ORX89732.1 - 3.8e-32 111.3 0.0 4.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX89732.1 - 4.2e-18 65.8 0.0 5.5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX89732.1 - 1.4e-08 34.9 0.5 1.1e-05 25.5 0.1 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 ORX89732.1 - 0.07 12.6 0.1 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltr_RsmB-F PF01189.17 ORX89732.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NAD_binding_8 PF13450.6 ORX89733.1 - 3.5e-15 56.0 0.0 7.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORX89733.1 - 1.5e-12 47.5 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ORX89733.1 - 6.1e-05 22.8 0.1 0.00065 19.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX89733.1 - 0.00076 18.8 0.0 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX89733.1 - 0.0015 17.7 0.0 0.0085 15.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ORX89733.1 - 0.0053 16.7 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORX89733.1 - 0.011 14.9 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORX89733.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 ORX89733.1 - 0.061 13.9 0.0 0.23 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORX89733.1 - 0.086 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 ORX89733.1 - 0.12 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORX89733.1 - 0.16 10.6 0.0 1 8.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Actin PF00022.19 ORX89734.1 - 7e-90 301.6 0.0 3e-88 296.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORX89734.1 - 0.00044 19.2 0.0 0.027 13.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein CENP-U PF13097.6 ORX89735.1 - 0.0035 17.3 0.6 0.0044 17.0 0.6 1.2 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit GBP PF02263.19 ORX89735.1 - 0.037 13.3 0.4 0.043 13.1 0.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AA_synth PF06684.11 ORX89736.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Amino acid synthesis CI-B14_5a PF07347.12 ORX89737.1 - 0.0085 16.0 2.0 0.0091 15.8 0.8 1.8 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Gpr1_Fun34_YaaH PF01184.19 ORX89738.1 - 2.6e-71 239.5 18.8 3e-71 239.3 18.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SLC3A2_N PF16028.5 ORX89738.1 - 0.17 11.5 1.9 0.99 9.0 0.5 2.5 2 1 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF4395 PF14340.6 ORX89738.1 - 5.5 7.3 18.9 4.4 7.6 12.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4395) LPMO_10 PF03067.15 ORX89739.1 - 2.2e-05 25.2 0.0 3.7e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX89739.1 - 0.0021 18.0 0.0 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 GUCT PF08152.12 ORX89739.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 GUCT (NUC152) domain DUF3449 PF11931.8 ORX89740.1 - 5.5e-79 264.2 0.9 5.5e-79 264.2 0.9 3.6 3 2 1 4 4 4 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 ORX89740.1 - 1.7e-25 89.3 7.8 2.3e-25 88.9 3.1 2.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 ORX89740.1 - 1.8e-13 50.1 1.5 4.5e-13 48.8 1.5 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 ORX89740.1 - 1.1e-08 35.1 5.1 1.4e-05 25.3 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX89740.1 - 2.1e-06 27.9 1.7 2.1e-06 27.9 1.7 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORX89740.1 - 0.012 16.0 4.1 0.054 13.8 0.8 3.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORX89740.1 - 0.025 15.4 3.0 8.9 7.4 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.12 ORX89740.1 - 0.049 13.7 0.5 0.049 13.7 0.5 3.8 3 1 0 3 3 3 0 DBF zinc finger DUF3802 PF12290.8 ORX89740.1 - 0.12 12.9 1.0 0.23 12.0 0.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3802) zf-Di19 PF05605.12 ORX89740.1 - 0.21 11.9 0.5 3.4 8.0 0.1 2.7 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.11 ORX89740.1 - 0.24 11.8 4.8 0.65 10.4 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) GFA PF04828.14 ORX89740.1 - 0.24 11.8 0.7 4.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4451 PF14616.6 ORX89740.1 - 0.43 10.8 3.5 0.21 11.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) zf-C2H2 PF00096.26 ORX89740.1 - 4.9 7.8 5.8 24 5.6 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type WH1 PF00568.23 ORX89741.1 - 1.1e-21 76.9 0.0 1.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORX89741.1 - 1.5e-15 57.2 0.1 3e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 ORX89741.1 - 8.8e-05 22.2 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 WH2 motif Pkinase PF00069.25 ORX89742.1 - 1.3e-61 208.3 0.0 1.5e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89742.1 - 9.3e-30 103.8 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX89742.1 - 7.9e-09 34.9 0.1 9.1e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX89742.1 - 4.8e-07 29.3 0.3 6.7e-07 28.9 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX89742.1 - 2e-05 24.1 0.0 5.5e-05 22.6 0.0 1.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORX89742.1 - 0.00015 21.8 0.3 0.027 14.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX89742.1 - 0.00039 19.3 0.0 0.00064 18.6 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase DUF4135 PF13575.6 ORX89742.1 - 0.021 14.2 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Choline_kinase PF01633.20 ORX89742.1 - 0.073 12.6 1.2 0.15 11.6 1.1 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Mt_ATP-synt_D PF05873.12 ORX89743.1 - 4.5e-21 75.3 3.0 5.4e-21 75.0 3.0 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Pet20 PF08692.10 ORX89743.1 - 0.00082 20.1 0.0 0.002 18.9 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial protein Pet20 HALZ PF02183.18 ORX89743.1 - 0.01 16.0 1.8 0.13 12.5 0.3 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper 120_Rick_ant PF12574.8 ORX89743.1 - 0.02 14.1 1.0 0.1 11.8 1.0 1.8 1 1 0 1 1 1 0 120 KDa Rickettsia surface antigen DUF1664 PF07889.12 ORX89743.1 - 0.024 14.7 0.7 1.3 9.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 ORX89743.1 - 0.039 14.4 1.0 1.4 9.4 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF2408 PF10303.9 ORX89743.1 - 0.058 14.0 1.7 0.37 11.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 ORX89743.1 - 0.13 12.3 4.1 5.2 7.1 0.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APC_N_CC PF16689.5 ORX89743.1 - 0.14 12.3 0.6 6.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Spc24 PF08286.11 ORX89743.1 - 0.29 11.4 3.7 4.7 7.5 0.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 ORX89743.1 - 0.54 10.5 4.8 2.1 8.6 0.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2570 PF10828.8 ORX89743.1 - 0.64 9.9 3.1 6.2 6.7 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DivIC PF04977.15 ORX89743.1 - 0.86 9.4 4.7 9.8 6.0 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator AAA_15 PF13175.6 ORX89744.1 - 0.0076 16.0 7.2 0.0095 15.7 7.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF2151 PF10221.9 ORX89744.1 - 0.09 11.4 11.6 0.11 11.1 11.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator HisKA PF00512.25 ORX89744.1 - 0.23 11.5 1.6 3.3 7.8 0.0 3.0 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain SOBP PF15279.6 ORX89744.1 - 0.31 11.6 6.3 0.41 11.2 6.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF668 PF05003.12 ORX89744.1 - 0.4 11.2 4.6 0.97 9.9 1.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF668) RR_TM4-6 PF06459.12 ORX89744.1 - 0.53 10.1 19.7 0.8 9.5 19.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 ORX89744.1 - 3.3 7.4 14.9 6 6.6 14.9 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORX89744.1 - 7.1 7.1 20.2 13 6.2 20.2 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 ORX89744.1 - 8.3 4.2 11.1 11 3.8 11.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 ORX89744.1 - 9.9 4.8 15.1 13 4.4 15.1 1.1 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 ORX89746.1 - 1.4e-33 113.4 65.6 0.00041 20.6 2.0 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX89746.1 - 6.5e-22 76.3 58.7 0.0038 18.0 0.3 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX89746.1 - 2.5e-21 75.1 70.9 1.4e-05 25.3 1.1 11.0 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORX89746.1 - 4.2e-09 36.6 29.2 0.0062 16.8 6.1 5.2 2 1 2 5 5 5 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORX89746.1 - 0.001 19.3 0.2 0.001 19.3 0.2 8.0 8 0 0 8 8 8 1 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 ORX89746.1 - 0.018 14.9 3.7 1.5 8.7 0.1 4.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 ORX89746.1 - 0.026 14.9 22.7 0.082 13.3 0.3 6.9 8 0 0 8 8 8 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORX89746.1 - 0.031 14.9 28.7 1 10.0 0.0 7.4 3 2 5 8 8 8 0 FOXP coiled-coil domain DUF2225 PF09986.9 ORX89746.1 - 0.046 13.4 0.4 0.046 13.4 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_12 PF18658.1 ORX89746.1 - 0.087 12.4 5.1 0.43 10.2 0.0 3.3 2 1 2 4 4 4 0 Zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 ORX89746.1 - 0.11 12.6 36.8 0.72 10.0 5.8 8.1 3 2 6 9 9 9 0 Aberrant zinc-finger OrsD PF12013.8 ORX89746.1 - 0.17 12.3 0.1 0.17 12.3 0.1 5.4 3 1 2 5 5 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D CCAP PF11105.8 ORX89746.1 - 0.2 11.6 0.0 0.2 11.6 0.0 3.5 4 2 1 5 5 4 0 Arthropod cardioacceleratory peptide 2a zf_Hakai PF18408.1 ORX89746.1 - 1 9.1 0.0 1 9.1 0.0 5.4 7 0 0 7 7 7 0 C2H2 Hakai zinc finger domain zf-Di19 PF05605.12 ORX89746.1 - 2.8 8.3 41.0 0.26 11.6 1.1 6.1 2 1 6 8 8 7 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 ORX89746.1 - 3.5 7.7 15.7 9 6.4 0.1 5.1 4 1 0 4 4 4 0 BED zinc finger USP7_C2 PF14533.6 ORX89747.1 - 5.1e-72 241.9 0.7 5.5e-70 235.3 0.2 3.1 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 ORX89747.1 - 1.6e-71 240.5 0.0 3.1e-69 232.9 0.0 2.6 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 ORX89747.1 - 3.3e-48 164.4 0.5 5.8e-48 163.6 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX89747.1 - 7.1e-20 71.8 0.0 1.7e-19 70.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORX89747.1 - 2.9e-10 40.3 0.1 2.2e-09 37.5 0.0 2.6 2 1 1 3 3 3 1 MATH domain Rad60-SLD PF11976.8 ORX89747.1 - 0.0015 18.3 0.4 2.6 8.0 0.0 4.7 4 1 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like Thioredoxin PF00085.20 ORX89752.1 - 7.5e-51 170.4 0.1 1.2e-24 86.2 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 ORX89752.1 - 1.1e-22 80.8 0.4 9.6e-14 51.7 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 ORX89752.1 - 5.3e-09 36.5 1.4 0.0035 17.8 0.1 4.0 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORX89752.1 - 9.1e-06 25.9 0.4 1 9.7 0.0 4.3 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 ORX89752.1 - 5.7e-05 23.1 0.0 2.8 8.0 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin domain HyaE PF07449.11 ORX89752.1 - 0.0012 18.8 0.0 10 6.1 0.0 3.8 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 ORX89752.1 - 0.0093 15.8 0.1 17 5.2 0.0 3.5 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 ORX89752.1 - 0.054 13.2 0.1 2.4 7.8 0.0 3.1 3 1 0 3 3 3 0 Thioredoxin OST3_OST6 PF04756.13 ORX89752.1 - 0.061 12.7 0.4 2.8 7.2 0.0 3.0 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Nucleoporin2 PF04096.14 ORX89753.1 - 2.8e-50 170.3 0.0 4.6e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 ORX89753.1 - 1.8e-07 31.9 71.6 2.1e-05 25.3 28.4 10.3 2 2 7 9 9 9 4 Nucleoporin FG repeat region SH3_1 PF00018.28 ORX89755.1 - 2.1e-05 24.0 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX89755.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX89755.1 - 0.0083 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain INTS2 PF14750.6 ORX89757.1 - 1.6e-05 22.7 2.6 2.3e-05 22.2 2.6 1.1 1 0 0 1 1 1 1 Integrator complex subunit 2 QSregVF PF13652.6 ORX89758.1 - 0.098 12.7 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Cyclin PF08613.11 ORX89759.1 - 6.9e-39 133.8 1.1 8.6e-39 133.5 0.3 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX89759.1 - 0.00082 19.1 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DELLA PF12041.8 ORX89759.1 - 0.097 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DUF3123 PF11321.8 ORX89759.1 - 0.57 10.9 4.7 2.2 8.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Catalase PF00199.19 ORX89760.1 - 2.9e-170 566.5 0.0 4.2e-170 565.9 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 ORX89760.1 - 3.4e-29 101.4 0.0 5.4e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORX89760.1 - 1.6e-18 66.7 0.2 3.6e-18 65.5 0.2 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 ORX89760.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family NAPRTase PF04095.16 ORX89760.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family TRP PF06011.12 ORX89761.1 - 4.6e-35 121.2 28.2 5.5e-33 114.3 28.2 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 ORX89761.1 - 0.00043 20.7 0.0 0.00073 20.0 0.0 1.3 1 0 0 1 1 1 1 ML domain Ninjurin PF04923.12 ORX89761.1 - 1.4 8.9 5.9 15 5.5 0.1 3.3 3 0 0 3 3 3 0 Ninjurin DUF1647 PF07801.11 ORX89762.1 - 2.7e-05 24.0 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) zf-RING_2 PF13639.6 ORX89763.1 - 7.4e-10 39.0 3.5 1.5e-09 38.0 3.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORX89763.1 - 3.5e-08 33.3 1.4 8.3e-08 32.1 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORX89763.1 - 3.1e-07 30.2 1.4 5.8e-07 29.3 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX89763.1 - 7.8e-06 25.8 2.2 7.8e-06 25.8 2.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORX89763.1 - 8.5e-05 22.8 3.0 0.00022 21.4 3.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORX89763.1 - 0.00015 21.5 1.1 0.00031 20.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORX89763.1 - 0.00064 19.8 0.2 0.00064 19.8 0.2 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 ORX89763.1 - 0.00091 18.9 1.1 0.0022 17.7 1.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX89763.1 - 0.0014 18.4 4.3 0.0073 16.1 4.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORX89763.1 - 0.0071 16.4 0.8 0.023 14.7 0.8 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 ORX89763.1 - 0.01 15.7 0.4 0.022 14.5 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.8 ORX89763.1 - 0.021 13.5 0.1 0.041 12.5 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FANCL_C PF11793.8 ORX89763.1 - 0.059 13.6 1.5 0.13 12.5 1.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain FYVE PF01363.21 ORX89763.1 - 0.074 13.2 1.2 0.26 11.5 1.2 1.9 1 0 0 1 1 1 0 FYVE zinc finger WD40 PF00400.32 ORX89763.1 - 0.22 12.4 2.8 2.6 9.0 0.7 3.6 4 0 0 4 4 3 0 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORX89763.1 - 0.23 11.1 2.0 0.58 9.8 2.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORX89763.1 - 0.31 10.9 2.4 0.9 9.4 2.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORX89763.1 - 0.36 10.6 1.9 0.77 9.6 1.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4200 PF13863.6 ORX89763.1 - 0.38 11.2 4.8 0.7 10.3 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3391 PF11871.8 ORX89763.1 - 9.3 6.8 10.7 0.44 11.1 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) RNA_pol_Rpc4 PF05132.14 ORX89764.1 - 1.1e-32 113.5 0.2 1.1e-32 113.5 0.2 2.1 3 0 0 3 3 3 1 RNA polymerase III RPC4 ETC_C1_NDUFA4 PF04800.12 ORX89765.1 - 6.5e-38 128.9 0.8 8.2e-38 128.6 0.8 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF5111 PF17138.4 ORX89765.1 - 0.063 13.1 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) PAC3 PF10178.9 ORX89766.1 - 1.4e-12 47.6 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Ydr279_N PF17745.1 ORX89767.1 - 3.2e-15 56.2 0.0 6.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 ORX89767.1 - 7.2e-14 52.3 0.1 1.4e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Val_tRNA-synt_C PF10458.9 ORX89767.1 - 0.025 14.9 0.3 0.064 13.6 0.3 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm PDZ_3 PF17815.1 ORX89767.1 - 0.04 13.8 0.2 0.077 12.9 0.2 1.5 1 0 0 1 1 1 0 PDZ domain RNase_HII PF01351.18 ORX89767.1 - 0.35 10.7 2.2 0.39 10.5 0.7 1.7 2 0 0 2 2 2 0 Ribonuclease HII 3-HAO PF06052.12 ORX89768.1 - 1.5e-65 219.5 0.2 1.8e-65 219.2 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 ORX89768.1 - 1e-06 28.3 0.1 2e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ORX89768.1 - 0.019 14.6 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 Cupin DZR PF12773.7 ORX89768.1 - 0.051 13.6 1.6 0.075 13.1 1.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon AAA_lid_3 PF17862.1 ORX89770.1 - 1.1e-08 34.8 0.0 1.9e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 ORX89771.1 - 5.6e-44 149.8 0.0 6.7e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX89771.1 - 1.2e-07 32.3 0.0 1.6e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 ORX89771.1 - 1.2e-06 28.8 0.0 2.5e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ORX89771.1 - 3.6e-06 26.8 0.0 4.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 ORX89771.1 - 3.3e-05 23.9 0.0 0.00022 21.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX89771.1 - 0.00032 21.0 0.1 0.0053 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX89771.1 - 0.00097 19.7 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORX89771.1 - 0.0014 19.0 0.0 0.002 18.5 0.0 1.4 1 1 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 ORX89771.1 - 0.0016 18.2 0.0 0.0078 16.0 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 ORX89771.1 - 0.0017 18.5 0.0 0.0025 18.0 0.0 1.4 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORX89771.1 - 0.0017 18.1 0.0 0.039 13.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 ORX89771.1 - 0.0027 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 ORX89771.1 - 0.003 18.1 0.0 0.0043 17.6 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 ORX89771.1 - 0.0043 17.1 0.0 0.0061 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORX89771.1 - 0.006 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 ORX89771.1 - 0.0075 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 ORX89771.1 - 0.0088 15.9 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 ORX89771.1 - 0.0095 15.2 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 ORX89771.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORX89771.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX89771.1 - 0.013 15.6 0.0 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORX89771.1 - 0.024 14.9 0.0 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 ORX89771.1 - 0.031 14.3 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORX89771.1 - 0.039 13.7 0.0 0.058 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ORX89771.1 - 0.04 13.3 0.0 7.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 ORX89771.1 - 0.043 13.6 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORX89771.1 - 0.043 13.5 0.0 0.069 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORX89771.1 - 0.057 13.3 0.0 0.28 11.1 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 ORX89771.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 ORX89771.1 - 0.14 12.1 0.1 0.56 10.1 0.1 2.0 1 1 0 1 1 1 0 NACHT domain ATPase PF06745.13 ORX89771.1 - 0.22 10.9 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 KaiC Complex1_LYR PF05347.15 ORX89772.1 - 0.0006 19.8 0.1 0.00096 19.2 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF572 PF04502.13 ORX89772.1 - 0.0078 15.9 1.3 0.0084 15.8 1.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Complex1_LYR_2 PF13233.6 ORX89772.1 - 0.01 16.5 1.0 0.013 16.2 1.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like LIN52 PF10044.9 ORX89772.1 - 0.032 14.9 0.8 0.037 14.7 0.8 1.1 1 0 0 1 1 1 0 Retinal tissue protein SNARE PF05739.19 ORX89773.1 - 0.0028 17.6 1.4 0.0074 16.3 0.0 2.6 2 1 0 2 2 2 1 SNARE domain TRC8_N PF13705.6 ORX89773.1 - 0.19 10.6 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain Pox_A_type_inc PF04508.12 ORX89773.1 - 1.2 9.0 10.9 6.2 6.9 0.4 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF2924 PF11149.8 ORX89773.1 - 1.8 8.9 4.7 1.1 9.7 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) OmpH PF03938.14 ORX89773.1 - 9.8 6.5 23.4 2.6 8.4 6.3 3.2 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) E1_DerP2_DerF2 PF02221.15 ORX89774.1 - 8.1e-21 74.8 0.0 9.5e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 ORX89774.1 - 0.21 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Nfu_N PF08712.11 ORX89775.1 - 5.6e-31 106.5 0.2 1.4e-30 105.2 0.2 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORX89775.1 - 6.6e-27 93.5 0.1 2.4e-26 91.7 0.1 1.9 2 0 0 2 2 2 1 NifU-like domain zf-C2H2 PF00096.26 ORX89776.1 - 0.043 14.3 0.5 0.11 13.1 0.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_M1 PF01433.20 ORX89777.1 - 6.8e-45 153.3 0.0 1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORX89777.1 - 2e-42 143.8 0.6 3.9e-42 142.9 0.6 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORX89777.1 - 4.5e-29 102.0 0.0 6.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain EamA PF00892.20 ORX89778.1 - 9.7e-24 84.1 41.6 7.9e-13 48.8 19.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family DMT_YdcZ PF04657.13 ORX89778.1 - 0.051 13.8 23.5 0.027 14.8 9.2 3.0 2 1 1 3 3 3 0 Putative inner membrane exporter, YdcZ RGS PF00615.19 ORX89779.1 - 4.9e-10 39.7 1.5 7.3e-10 39.1 1.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX89779.1 - 8.7e-07 28.9 19.4 1.9e-06 27.8 19.5 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Arrestin_C PF02752.22 ORX89780.1 - 5e-17 62.6 0.8 1.2e-16 61.4 0.8 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX89780.1 - 5.8e-11 42.6 0.4 6.3e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX89780.1 - 0.0092 15.2 1.4 6 5.9 0.2 3.1 2 1 1 3 3 3 3 Rgp1 dbPDZ_assoc PF16610.5 ORX89780.1 - 0.01 16.1 1.9 0.033 14.4 1.9 1.9 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 AglB_L1 PF18079.1 ORX89780.1 - 0.017 15.4 0.0 0.096 13.0 0.0 2.2 2 0 0 2 2 2 0 Archaeal glycosylation protein B long peripheral domain MFS_1 PF07690.16 ORX89781.1 - 7.5e-37 127.1 52.9 5e-29 101.3 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX89781.1 - 5.5e-07 28.8 5.5 5.5e-07 28.8 5.5 3.1 1 1 2 3 3 3 2 Sugar (and other) transporter Orf78 PF06024.12 ORX89781.1 - 0.092 13.1 0.1 0.68 10.3 0.1 2.3 2 0 0 2 2 2 0 Orf78 (ac78) COX4 PF02936.14 ORX89781.1 - 0.2 11.7 0.1 1.7 8.6 0.1 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV DUF5362 PF17319.2 ORX89781.1 - 1.1 9.2 11.5 3.1 7.7 0.5 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5362) Dus PF01207.17 ORX89782.1 - 2.1e-80 270.2 0.0 3.3e-80 269.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 ORX89782.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase SOR_SNZ PF01680.17 ORX89782.1 - 0.042 13.6 0.0 0.43 10.3 0.0 2.1 1 1 1 2 2 2 0 SOR/SNZ family ThiG PF05690.14 ORX89782.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF702 PF05142.12 ORX89782.1 - 0.23 11.9 12.4 0.5 10.8 12.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Velvet PF11754.8 ORX89783.1 - 8.2e-39 134.0 0.1 1.5e-21 77.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor DUF1648 PF07853.11 ORX89784.1 - 0.00057 19.5 0.4 0.032 13.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1648) DUF3671 PF12420.8 ORX89784.1 - 4.7 7.3 8.1 14 5.8 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function RabGAP-TBC PF00566.18 ORX89785.1 - 2.3e-53 181.1 2.0 2.8e-53 180.7 2.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_34 PF05637.12 ORX89786.1 - 2.5e-34 119.1 1.5 4e-32 111.8 1.5 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORX89786.1 - 0.0026 17.4 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Staphylcoagulse PF04022.12 ORX89786.1 - 0.16 11.5 0.4 0.44 10.1 0.4 1.7 1 0 0 1 1 1 0 Staphylocoagulase repeat CYSTM PF12734.7 ORX89787.1 - 2e-07 31.2 25.1 2e-07 31.2 25.1 3.4 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance DUF2011 PF09428.10 ORX89788.1 - 5.9e-07 29.7 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Pep1_7 PF17232.2 ORX89788.1 - 0.024 15.1 3.2 0.041 14.3 2.0 2.0 1 1 0 1 1 1 0 Elicitor peptide 1-7 SAE2 PF08573.10 ORX89790.1 - 8.8e-16 59.0 7.2 1.9e-07 32.1 0.3 2.9 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus NYD-SP28 PF14772.6 ORX89790.1 - 0.0023 18.0 0.7 0.0057 16.7 0.7 1.7 1 0 0 1 1 1 1 Sperm tail Mito_carr PF00153.27 ORX89791.1 - 2.7e-48 161.9 6.2 9.9e-17 60.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FHIPEP PF00771.20 ORX89791.1 - 0.019 13.4 0.5 0.027 13.0 0.5 1.1 1 0 0 1 1 1 0 FHIPEP family Rpp20 PF12328.8 ORX89792.1 - 8.8e-09 35.4 0.1 1.1e-08 35.1 0.1 1.0 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 ORX89792.1 - 0.00017 21.3 0.0 0.00022 21.0 0.0 1.3 1 1 0 1 1 1 1 Alba Moricin PF06451.11 ORX89792.1 - 0.041 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Moricin COX17 PF05051.13 ORX89793.1 - 3.9e-21 75.1 8.4 4.7e-21 74.9 8.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) WD40 PF00400.32 ORX89794.1 - 2.7e-24 85.0 17.3 5.7e-05 23.8 0.2 10.4 11 1 0 11 11 11 6 WD domain, G-beta repeat C2 PF00168.30 ORX89794.1 - 3e-22 78.9 0.0 7.4e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain HELP PF03451.14 ORX89794.1 - 6.2e-15 54.8 0.0 1.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 ORX89794.1 - 3.8e-10 39.9 0.6 1.5 9.2 0.0 6.7 5 3 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORX89794.1 - 0.0019 16.8 0.0 0.041 12.4 0.0 2.8 3 0 0 3 3 3 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 ORX89794.1 - 0.0022 17.1 0.2 5.1 6.0 0.0 3.2 2 1 1 3 3 3 2 Coatomer WD associated region PQQ_3 PF13570.6 ORX89794.1 - 0.011 16.2 0.0 2.6 8.7 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain Glycos_transf_3 PF00591.21 ORX89795.1 - 9.7e-90 300.6 0.0 1.2e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ORX89795.1 - 4.6e-07 29.6 0.1 1.2e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain EIID-AGA PF03613.14 ORX89796.1 - 0.0078 15.4 1.2 0.23 10.6 1.1 2.4 1 1 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component GPR_Gpa2_C PF11970.8 ORX89796.1 - 0.011 15.8 0.5 0.034 14.2 0.5 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term CybS PF05328.12 ORX89796.1 - 0.026 14.2 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit DUF5058 PF16481.5 ORX89796.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5058) FecCD PF01032.18 ORX89796.1 - 0.43 9.5 11.4 0.18 10.8 8.5 1.7 1 1 0 1 1 1 0 FecCD transport family DUF4131 PF13567.6 ORX89796.1 - 2.7 7.6 13.5 2 8.0 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) DUF4834 PF16118.5 ORX89796.1 - 2.7 9.0 8.0 1.4 9.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Bac_export_2 PF01312.19 ORX89796.1 - 9.5 5.3 8.4 1.7 7.7 3.9 1.9 1 1 2 3 3 3 0 FlhB HrpN YscU SpaS Family CAP PF00188.26 ORX89797.1 - 9.7e-18 65.2 0.0 1.5e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family E1-E2_ATPase PF00122.20 ORX89798.1 - 8e-38 129.8 0.2 8e-38 129.8 0.2 3.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX89798.1 - 3e-17 63.6 0.0 7.8e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX89798.1 - 1e-14 54.6 14.8 1e-14 54.6 14.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 ORX89798.1 - 6.9e-09 35.3 0.0 1.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORX89798.1 - 1.7e-08 34.4 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX89798.1 - 0.0059 16.4 0.1 0.037 13.8 0.1 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX89798.1 - 0.049 14.0 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase COX7C PF02935.16 ORX89798.1 - 0.083 13.2 2.5 0.24 11.7 1.9 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc CtaG_Cox11 PF04442.14 ORX89799.1 - 2.4e-64 215.9 0.4 3.1e-64 215.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 LRR_4 PF12799.7 ORX89800.1 - 1.1e-07 32.0 10.9 0.2 12.1 0.2 5.9 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX89800.1 - 0.077 12.8 9.6 1.1 9.1 0.1 5.7 5 2 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 ORX89800.1 - 0.096 12.8 11.6 1e+02 3.3 0.1 7.5 9 0 0 9 9 9 0 Leucine Rich repeat Pkinase PF00069.25 ORX89801.1 - 2.5e-50 171.3 0.0 2.8e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89801.1 - 8.6e-26 90.8 0.0 1.1e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX89801.1 - 5.5e-08 32.5 0.0 7.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORX89801.1 - 1.7e-05 24.9 0.1 4.7e-05 23.4 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORX89801.1 - 7e-05 22.5 1.0 0.0037 16.9 0.1 2.1 1 1 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 ORX89801.1 - 0.0015 17.9 0.1 0.0023 17.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX89801.1 - 0.004 16.1 0.1 0.0048 15.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PIP49_C PF12260.8 ORX89801.1 - 0.028 14.1 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF4998 PF16389.5 ORX89802.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function RhoGAP PF00620.27 ORX89803.1 - 1e-45 155.3 0.6 3.1e-45 153.7 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORX89803.1 - 4.5e-11 42.9 0.1 3.8e-10 39.9 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mg_trans_NIPA PF05653.14 ORX89804.1 - 3.8e-26 91.9 23.9 2.4e-13 49.9 9.3 2.5 2 1 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORX89804.1 - 0.0012 19.0 1.4 0.0012 19.0 1.4 3.8 4 0 0 4 4 4 1 EamA-like transporter family DUF4079 PF13301.6 ORX89804.1 - 0.07 13.3 1.5 8 6.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2207 PF09972.9 ORX89804.1 - 1.3 7.7 14.5 1.6 7.4 4.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FAM72 PF14976.6 ORX89805.1 - 4.8e-45 153.2 8.5 5.9e-45 153.0 8.5 1.1 1 0 0 1 1 1 1 FAM72 protein Eapp_C PF10238.9 ORX89805.1 - 0.24 11.5 0.3 0.24 11.5 0.3 2.0 2 1 0 2 2 2 0 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 ORX89805.1 - 5.6 7.2 12.1 16 5.7 12.1 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Kinesin PF00225.23 ORX89806.1 - 8.6e-90 301.0 0.0 9.7e-90 300.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX89806.1 - 2.2e-15 56.9 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Paramyxo_C PF01692.18 ORX89807.1 - 5.4 6.3 7.1 0.99 8.8 0.4 2.1 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C Aa_trans PF01490.18 ORX89808.1 - 4.1e-52 177.3 34.0 4.7e-52 177.1 34.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX89808.1 - 1.9e-06 26.9 41.7 0.00083 18.3 22.8 2.8 2 1 0 2 2 2 2 Spore germination protein DUF3377 PF11857.8 ORX89808.1 - 1.7 8.6 4.4 7.9 6.5 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) PAS PF00989.25 ORX89809.1 - 5.6e-10 39.2 0.0 0.00042 20.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX89809.1 - 4.3e-09 36.5 0.0 5.4e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORX89809.1 - 7.9e-08 32.5 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 ORX89809.1 - 3e-06 27.3 0.0 0.0032 17.6 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORX89809.1 - 0.002 18.4 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold WD40 PF00400.32 ORX89811.1 - 1.6e-10 41.3 0.6 1.3e-07 32.2 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89811.1 - 6.8e-06 26.3 0.1 0.0076 16.5 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX89811.1 - 0.0011 17.7 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 ORX89811.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Senescence PF06911.12 ORX89812.1 - 1.1e-39 136.7 2.5 1.2e-39 136.5 2.5 1.0 1 0 0 1 1 1 1 Senescence-associated protein ThrE PF06738.12 ORX89813.1 - 1.2e-61 208.2 9.7 1.4e-54 185.0 0.4 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORX89813.1 - 3.5e-11 43.3 16.0 6.9e-09 35.9 5.0 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE ATP_sub_h PF10775.9 ORX89814.1 - 3.5e-23 81.4 0.1 4.3e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 ORX89814.1 - 0.005 17.2 0.0 0.0063 16.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Mannosyl_trans2 PF04188.13 ORX89815.1 - 5.1e-77 260.1 35.8 6.9e-77 259.6 35.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) SIS PF01380.22 ORX89816.1 - 9.3e-68 226.1 0.2 5.7e-37 126.5 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORX89816.1 - 3e-15 56.6 0.0 9.3e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORX89816.1 - 9.6e-13 48.1 0.0 2.1e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORX89816.1 - 0.00068 18.6 0.1 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORX89816.1 - 0.021 14.9 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 SIS domain GATase_2 PF00310.21 ORX89816.1 - 0.081 11.6 0.1 0.18 10.5 0.2 1.5 1 1 1 2 2 2 0 Glutamine amidotransferases class-II ABC_tran PF00005.27 ORX89817.1 - 4.1e-26 92.1 0.0 1e-25 90.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX89817.1 - 2.8e-24 85.9 18.3 4.4e-24 85.2 18.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX89817.1 - 1.5e-08 34.8 0.1 3.3e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 ORX89817.1 - 0.049 13.0 0.1 4.1 6.7 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 ORX89817.1 - 0.064 13.7 0.2 0.42 11.0 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORX89817.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 ORX89817.1 - 0.069 12.9 0.0 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF2090 PF09863.9 ORX89817.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) AAA_15 PF13175.6 ORX89817.1 - 0.088 12.5 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 ORX89817.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TMEM208_SND2 PF05620.11 ORX89817.1 - 3.6 7.4 4.6 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ABC_tran PF00005.27 ORX89818.1 - 4.6e-25 88.7 0.0 8.6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX89818.1 - 1.4e-16 60.6 29.7 2e-16 60.0 29.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX89818.1 - 5.5e-09 36.3 0.2 2.8e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORX89818.1 - 0.018 14.8 0.2 0.069 12.9 0.2 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 ORX89818.1 - 0.022 14.2 0.1 0.29 10.5 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX89818.1 - 0.056 13.9 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORX89818.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain p450 PF00067.22 ORX89819.1 - 2.8e-95 319.8 0.0 3.2e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 ORX89819.1 - 2e-05 24.8 0.0 6.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin Tyrosinase PF00264.20 ORX89820.1 - 3.5e-14 53.6 11.0 5.7e-14 52.9 11.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Ribonuclease_T2 PF00445.18 ORX89821.1 - 6.7e-38 130.7 0.1 9.1e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Pmp3 PF01679.17 ORX89822.1 - 7.5e-22 77.3 7.0 8.5e-22 77.1 7.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Hexokinase_2 PF03727.16 ORX89823.1 - 4.9e-59 199.7 0.0 7.2e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX89823.1 - 8.2e-36 123.8 0.0 1.2e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Steroid_dh PF02544.16 ORX89824.1 - 4.9e-38 130.5 9.3 4.9e-38 130.5 9.3 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 ORX89824.1 - 1.5e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 ORX89824.1 - 0.037 13.6 4.3 0.079 12.5 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1295) GAD-like PF08887.11 ORX89824.1 - 0.1 12.4 1.0 0.19 11.5 1.0 1.4 1 0 0 1 1 1 0 GAD-like domain Syntaxin PF00804.25 ORX89825.1 - 6.8e-26 91.2 15.6 1.7e-20 73.6 8.9 2.2 1 1 1 2 2 2 2 Syntaxin SNARE PF05739.19 ORX89825.1 - 3.3e-12 46.2 0.2 6.8e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 SNARE domain DUF4094 PF13334.6 ORX89825.1 - 0.0079 16.6 4.2 0.045 14.2 0.8 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4094) Tetraspanin PF00335.20 ORX89825.1 - 0.05 13.3 0.7 0.1 12.3 0.7 1.6 1 0 0 1 1 1 0 Tetraspanin family DUF3106 PF11304.8 ORX89825.1 - 0.08 13.4 5.8 0.37 11.3 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DASH_Dam1 PF08653.10 ORX89825.1 - 0.084 12.7 3.7 0.42 10.5 0.3 3.0 2 2 1 3 3 3 0 DASH complex subunit Dam1 HOIP-UBA PF16678.5 ORX89825.1 - 0.18 11.8 4.2 0.23 11.5 1.6 2.2 2 0 0 2 2 2 0 HOIP UBA domain pair Gp-FAR-1 PF05823.12 ORX89825.1 - 0.27 11.6 7.9 0.46 10.8 0.8 2.2 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NPV_P10 PF05531.12 ORX89825.1 - 0.3 11.6 5.6 1.3 9.6 0.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 ORX89825.1 - 0.3 11.6 7.0 3.2 8.3 0.5 3.1 2 2 0 2 2 2 0 Spectrin repeat RPN6_N PF18055.1 ORX89825.1 - 0.68 10.3 6.1 0.19 12.1 2.3 2.1 2 1 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain Turandot PF07240.11 ORX89825.1 - 1.2 9.2 3.8 0.81 9.7 0.3 2.5 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot BCL_N PF04714.13 ORX89825.1 - 1.2 9.2 4.7 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Plk4_PB2 PF18409.1 ORX89825.1 - 1.9 9.2 8.2 3.6 8.3 0.6 3.2 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 SKA1 PF07160.12 ORX89825.1 - 2 8.2 12.5 0.11 12.3 3.6 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 LMBR1 PF04791.16 ORX89825.1 - 2.8 6.8 12.9 0.54 9.1 6.5 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 ORX89825.1 - 3.2 7.8 7.9 2.1 8.4 1.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 ORX89825.1 - 3.3 8.2 6.4 3.1 8.3 0.9 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 ORX89825.1 - 8.5 6.6 14.6 6.7 6.9 0.9 2.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.25 ORX89826.1 - 9.3e-14 51.6 10.4 2.5e-13 50.2 10.1 2.0 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORX89826.1 - 0.0056 16.7 3.2 0.015 15.3 3.2 1.8 1 0 0 1 1 1 1 SNARE domain Vps51 PF08700.11 ORX89826.1 - 0.0075 16.3 0.4 0.0075 16.3 0.4 2.8 4 1 0 4 4 4 1 Vps51/Vps67 PEP-utilisers_N PF05524.13 ORX89826.1 - 0.017 15.3 6.8 1.4 9.1 0.0 2.6 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal YfcL PF08891.11 ORX89826.1 - 0.027 14.8 0.6 0.13 12.6 0.4 2.3 1 1 1 2 2 2 0 YfcL protein PABP PF00658.18 ORX89826.1 - 0.11 12.7 1.2 0.23 11.7 0.2 2.0 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Med30 PF11315.8 ORX89826.1 - 0.27 11.4 9.8 0.035 14.3 2.9 2.6 1 1 2 3 3 3 0 Mediator complex subunit 30 DUF745 PF05335.13 ORX89826.1 - 3.5 7.3 8.3 0.19 11.5 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Insulin_TMD PF17870.1 ORX89826.1 - 4.1 7.6 6.6 8.3 6.6 6.6 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MSC PF09402.10 ORX89826.1 - 8.1 5.8 9.7 0.61 9.5 1.4 2.1 1 1 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF1847 PF08901.11 ORX89827.1 - 0.0074 15.9 0.7 0.018 14.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1847) Fam20C PF06702.12 ORX89827.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 MMS19_N PF14500.6 ORX89828.1 - 0.0055 16.3 0.1 2.8 7.4 0.0 3.2 2 2 1 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II TPR_6 PF13174.6 ORX89828.1 - 0.14 12.9 0.3 27 5.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.22 ORX89828.1 - 0.14 12.5 0.0 38 4.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat ATP-synt_C PF00137.21 ORX89829.1 - 1.5e-26 92.5 30.5 3.8e-15 56.0 10.3 2.5 3 0 0 3 3 3 2 ATP synthase subunit C Transket_pyr PF02779.24 ORX89833.1 - 9.6e-46 155.7 0.0 1.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORX89833.1 - 4.9e-43 145.9 0.0 9.8e-43 145.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ORX89833.1 - 0.0089 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II PI-PLC-X PF00388.19 ORX89835.1 - 7e-63 210.6 0.0 1.3e-62 209.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ORX89835.1 - 5.4e-40 136.3 0.5 1.1e-39 135.3 0.5 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ORX89835.1 - 1.5e-17 63.7 0.0 3.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 ORX89835.1 - 2.9e-05 24.5 0.7 8.7e-05 22.9 0.2 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Mcp5_PH PF12814.7 ORX89835.1 - 0.00057 20.0 0.4 0.0017 18.4 0.4 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_7 PF13499.6 ORX89835.1 - 0.00066 20.1 1.2 0.02 15.3 0.0 3.0 3 0 0 3 3 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX89835.1 - 0.0029 17.9 1.0 0.2 12.0 0.1 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PH_14 PF17787.1 ORX89835.1 - 0.014 15.3 0.1 0.038 13.8 0.1 1.8 1 0 0 1 1 1 0 PH domain EF-hand_1 PF00036.32 ORX89835.1 - 0.06 12.9 1.0 1.3 8.7 0.3 3.2 3 0 0 3 3 3 0 EF hand PH_12 PF16457.5 ORX89835.1 - 0.067 13.7 0.2 0.16 12.5 0.2 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_6 PF13405.6 ORX89835.1 - 0.28 11.2 7.0 0.27 11.3 0.5 3.6 4 0 0 4 4 4 0 EF-hand domain adh_short PF00106.25 ORX89836.1 - 3.4e-47 160.4 0.2 4.9e-47 159.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX89836.1 - 1.4e-38 132.8 0.1 1.5e-38 132.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX89836.1 - 4e-07 30.1 0.1 6.2e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX89836.1 - 6.4e-06 25.8 0.1 1.5e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX89836.1 - 0.00014 21.1 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.15 ORX89836.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.19 ORX89836.1 - 0.0075 15.3 0.1 0.0098 14.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 ORX89836.1 - 0.032 14.8 0.3 0.083 13.5 0.3 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ORX89836.1 - 0.038 13.9 0.5 0.094 12.6 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ORX89836.1 - 0.14 12.2 0.5 0.33 11.0 0.5 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NUDE_C PF04880.13 ORX89837.1 - 1.2e-10 42.2 5.1 1.2e-10 42.2 5.1 3.1 3 0 0 3 3 3 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 ORX89837.1 - 1.1e-05 25.5 30.2 0.0049 16.9 7.2 3.5 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 ORX89837.1 - 5.7e-05 22.1 21.5 5.7e-05 22.1 21.5 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein CENP-H PF05837.12 ORX89837.1 - 0.0029 18.0 8.7 0.0029 18.0 8.7 2.8 2 1 2 4 4 3 1 Centromere protein H (CENP-H) Herpes_UL25 PF01499.16 ORX89837.1 - 0.01 14.4 7.1 0.046 12.2 3.2 2.2 1 1 1 2 2 2 0 Herpesvirus UL25 family DUF4200 PF13863.6 ORX89837.1 - 0.03 14.7 23.8 0.042 14.2 13.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BRE1 PF08647.11 ORX89837.1 - 0.096 12.8 27.6 0.039 14.0 13.5 2.8 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase IFP_35_N PF07334.13 ORX89837.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.4 3 1 0 4 4 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF5082 PF16888.5 ORX89837.1 - 0.2 11.9 20.3 1 9.7 10.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) V_ATPase_I PF01496.19 ORX89837.1 - 0.22 9.4 10.9 0.36 8.7 10.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 ORX89837.1 - 0.26 11.9 20.8 2.7 8.7 5.9 3.7 2 1 2 4 4 4 0 Initiation control protein YabA ERM PF00769.19 ORX89837.1 - 0.35 10.7 29.9 0.023 14.5 17.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 ORX89837.1 - 0.36 10.3 30.9 0.03 13.8 15.9 2.8 2 1 1 3 3 3 0 Golgin subfamily A member 5 Taxilin PF09728.9 ORX89837.1 - 0.39 9.9 26.0 3.8 6.6 26.0 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Prefoldin_2 PF01920.20 ORX89837.1 - 0.4 10.7 25.5 0.89 9.5 1.5 3.9 4 0 0 4 4 4 0 Prefoldin subunit DUF2353 PF09789.9 ORX89837.1 - 0.42 9.9 24.3 0.015 14.7 11.8 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) MbeD_MobD PF04899.12 ORX89837.1 - 0.42 10.7 11.3 1.1 9.4 0.7 3.0 2 1 0 2 2 2 0 MbeD/MobD like Filament PF00038.21 ORX89837.1 - 0.56 9.7 25.1 0.85 9.1 6.3 2.9 2 1 1 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 ORX89837.1 - 0.62 10.3 32.6 3.2 7.9 17.1 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) WEMBL PF05701.11 ORX89837.1 - 0.83 8.3 21.7 1.4 7.6 21.7 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light EzrA PF06160.12 ORX89837.1 - 1.2 7.2 24.2 46 2.0 23.2 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA PRKG1_interact PF15898.5 ORX89837.1 - 1.3 9.9 28.3 0.3 12.0 14.2 2.7 2 1 0 3 3 2 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 ORX89837.1 - 1.6 9.2 22.8 1.5 9.2 7.5 2.2 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 ORX89837.1 - 2.5 7.4 13.9 19 4.5 14.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 ORX89837.1 - 2.7 8.4 21.1 1.2e+04 -3.5 21.1 2.3 1 1 0 1 1 0 0 YlqD protein DUF3450 PF11932.8 ORX89837.1 - 2.9 7.1 24.4 1.3 8.3 10.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 ORX89837.1 - 3.2 6.7 20.7 0.036 13.2 9.9 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 ORX89837.1 - 4 7.5 32.6 3.7 7.6 7.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 ORX89837.1 - 4.3 7.8 17.0 6.5 7.3 6.1 3.5 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.14 ORX89837.1 - 4.6 7.6 23.1 0.58 10.5 4.3 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 ORX89837.1 - 5.2 7.1 14.9 4.9 7.2 3.8 2.9 2 1 0 3 3 3 0 Laminin Domain II FapA PF03961.13 ORX89837.1 - 5.9 5.4 22.5 0.67 8.5 9.6 2.3 2 1 1 3 3 3 0 Flagellar Assembly Protein A Phlebovirus_NSM PF07246.11 ORX89837.1 - 6.4 6.1 9.0 1.8 7.9 4.9 1.9 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GAS PF13851.6 ORX89837.1 - 6.6 6.0 30.1 19 4.5 17.9 2.8 2 1 1 3 3 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 ORX89837.1 - 6.7 7.0 33.4 2.5 8.3 8.0 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 ORX89837.1 - 6.8 6.3 31.9 21 4.7 8.4 3.2 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 ORX89837.1 - 7.3 6.7 30.3 1.1 9.4 13.7 3.4 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 ORX89837.1 - 8 6.3 25.6 0.44 10.4 4.0 3.8 3 1 1 4 4 3 0 Septum formation initiator Muskelin_N PF06588.11 ORX89838.1 - 3.5e-82 275.1 1.6 5.5e-82 274.5 1.6 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 ORX89838.1 - 5.8e-23 80.6 8.9 4.1e-08 33.3 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX89838.1 - 3.1e-19 68.5 9.9 0.00055 20.1 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 ORX89838.1 - 3.2e-16 58.6 16.8 2e-06 27.3 0.2 5.8 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 ORX89838.1 - 3.3e-16 58.9 12.0 0.011 15.7 0.0 6.3 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 ORX89838.1 - 6.5e-16 58.1 9.2 0.0021 18.0 0.2 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORX89838.1 - 2.5e-08 33.5 14.4 0.00061 19.7 0.5 6.3 6 0 0 6 6 6 3 Kelch motif F5_F8_type_C PF00754.25 ORX89838.1 - 9.1e-07 29.0 3.3 1e-05 25.6 0.0 2.5 2 0 0 2 2 2 1 F5/8 type C domain XRCC1_N PF01834.16 ORX89838.1 - 0.009 16.0 0.4 0.023 14.7 0.4 1.6 1 0 0 1 1 1 1 XRCC1 N terminal domain DUF1861 PF08950.10 ORX89838.1 - 0.042 13.1 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1861) PseudoU_synth_1 PF01416.20 ORX89839.1 - 3e-35 120.9 0.0 8.6e-33 113.0 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF1764 PF08576.10 ORX89840.1 - 0.0039 18.1 0.0 0.0045 17.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) DUF968 PF06147.11 ORX89841.1 - 0.065 13.5 0.2 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF968) AIM3 PF17096.5 ORX89841.1 - 0.46 11.5 3.8 0.7 10.9 3.8 1.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Ribosomal_S26e PF01283.19 ORX89843.1 - 9.1e-54 180.5 6.8 1.1e-53 180.3 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf-CCCH PF00642.24 ORX89845.1 - 1.5e-16 59.8 16.8 4.4e-09 36.0 3.3 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX89845.1 - 7.6e-07 29.0 17.4 0.0011 18.9 3.1 2.4 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORX89845.1 - 0.00076 19.2 4.9 0.00076 19.2 4.9 2.7 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORX89845.1 - 0.0029 18.3 11.3 0.23 12.1 2.9 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 ORX89845.1 - 0.055 14.0 0.8 0.055 14.0 0.8 2.8 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CcmF_C PF16327.5 ORX89846.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DNA_ligase_A_M PF01068.21 ORX89847.1 - 8.4e-66 221.5 0.1 1.4e-65 220.8 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORX89847.1 - 1.8e-43 148.8 0.1 3.6e-43 147.9 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORX89847.1 - 1.1e-23 83.6 0.0 2.4e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 ORX89847.1 - 0.11 12.5 0.3 16 5.6 0.1 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Pkinase PF00069.25 ORX89848.1 - 1.8e-68 230.8 0.0 2.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89848.1 - 5e-32 111.2 0.0 6.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX89848.1 - 0.00097 18.5 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX89848.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX89848.1 - 0.0023 17.0 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORX89848.1 - 0.04 12.7 0.0 0.064 12.0 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 ORX89848.1 - 0.048 13.2 0.2 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 ORX89848.1 - 0.14 12.1 0.2 0.4 10.6 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ran_BP1 PF00638.18 ORX89849.1 - 1.3e-21 77.1 0.9 2.8e-21 76.0 0.9 1.6 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 ORX89849.1 - 2.2e-16 60.2 3.1 2.2e-16 60.2 3.1 6.7 5 3 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) GOLD_2 PF13897.6 ORX89849.1 - 3.2 8.3 6.1 5.8 7.4 0.7 3.3 2 2 0 2 2 2 0 Golgi-dynamics membrane-trafficking Clr2_transil PF16761.5 ORX89850.1 - 5.6e-23 81.6 1.3 1.5e-22 80.2 0.6 1.9 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 Nicastrin PF05450.15 ORX89851.1 - 2e-31 109.3 1.6 2.1e-30 106.0 1.6 2.1 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 ORX89851.1 - 0.003 17.3 0.0 0.004 16.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M28 RNA_pol_A_bac PF01000.26 ORX89852.1 - 8.8e-37 125.9 0.0 1.6e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORX89852.1 - 5e-20 70.7 0.0 6.3e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMT_C PF02799.15 ORX89853.1 - 4.1e-77 258.4 0.5 9.1e-77 257.3 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 ORX89853.1 - 3e-75 251.4 0.2 5.7e-75 250.5 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 ORX89853.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family SpoVIF PF14069.6 ORX89853.1 - 0.039 13.7 2.2 0.15 11.8 0.9 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F Acetyltransf_9 PF13527.7 ORX89853.1 - 0.051 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Methyltransf_12 PF08242.12 ORX89853.1 - 0.068 13.9 0.0 0.43 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 ORX89854.1 - 2.4e-65 221.1 0.0 1.7e-64 218.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF1863 PF08937.11 ORX89854.1 - 0.052 13.9 0.2 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) NAD_binding_10 PF13460.6 ORX89859.1 - 2.2e-09 37.5 0.0 3.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX89859.1 - 2.8e-07 30.3 0.0 3.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Thioredoxin_8 PF13905.6 ORX89860.1 - 7.8e-15 55.0 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 ORX89860.1 - 0.0054 16.7 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin MWFE PF15879.5 ORX89861.1 - 1.1e-19 70.3 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ACT_7 PF13840.6 ORX89862.1 - 6.6e-19 67.5 0.0 1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ORX89862.1 - 0.011 15.5 0.4 0.047 13.5 0.1 2.2 2 1 0 2 2 2 0 ACT domain DEAD PF00270.29 ORX89863.1 - 2.2e-49 167.6 0.0 5.1e-49 166.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX89863.1 - 2.9e-32 111.3 0.1 1.1e-29 103.0 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 ORX89863.1 - 0.0055 15.5 0.1 0.061 12.1 0.0 2.4 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SOBP PF15279.6 ORX89863.1 - 0.011 16.4 2.4 0.017 15.7 2.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_22 PF13401.6 ORX89863.1 - 0.082 13.2 1.5 1.2 9.4 0.4 2.9 1 1 1 2 2 2 0 AAA domain CDC45 PF02724.14 ORX89863.1 - 0.87 7.8 11.3 1.3 7.3 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CMS1 PF14617.6 ORX89863.1 - 1.5 8.1 0.0 1.5 8.1 0.0 2.9 2 1 0 2 2 1 0 U3-containing 90S pre-ribosomal complex subunit NPR3 PF03666.13 ORX89863.1 - 3 6.5 11.2 5.6 5.6 11.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 ORX89863.1 - 3 6.7 22.3 5.6 5.8 22.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.16 ORX89863.1 - 4.8 6.6 13.6 9.3 5.7 13.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2151 PF10221.9 ORX89863.1 - 8.3 4.9 10.5 12 4.3 10.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator CPSF100_C PF13299.6 ORX89863.1 - 9.2 6.4 13.1 17 5.6 13.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 ORX89863.1 - 9.5 6.5 28.4 0.63 10.4 23.0 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Bystin PF05291.11 ORX89864.1 - 1.2e-140 467.8 0.1 1.2e-140 467.8 0.1 1.4 2 0 0 2 2 2 1 Bystin Cwf_Cwc_15 PF04889.12 ORX89864.1 - 3.9 7.1 20.6 5.7 6.6 20.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein U1snRNP70_N PF12220.8 ORX89865.1 - 2.4e-27 95.4 1.4 3.7e-27 94.8 1.4 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 ORX89865.1 - 1.3e-14 53.8 0.0 3.8e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX89865.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif HCNGP PF07818.13 ORX89866.1 - 8.4e-34 116.1 0.5 1.4e-33 115.4 0.5 1.3 1 0 0 1 1 1 1 HCNGP-like protein zf-CCCH_4 PF18044.1 ORX89867.1 - 8.6e-18 63.7 34.8 8.3e-07 28.7 1.4 5.2 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH PF00642.24 ORX89867.1 - 3e-15 55.7 29.3 0.00011 22.1 1.9 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX89867.1 - 3.6e-12 45.9 42.8 0.0015 18.5 5.8 5.0 4 2 0 4 4 4 4 Zinc finger domain Torus PF16131.5 ORX89867.1 - 2.8e-09 37.6 22.0 0.0054 17.4 0.4 4.3 3 1 1 4 4 4 3 Torus domain zf-RING_2 PF13639.6 ORX89867.1 - 6.4e-06 26.4 7.7 6.4e-06 26.4 7.7 3.8 3 1 2 5 5 4 1 Ring finger domain zf-RING_5 PF14634.6 ORX89867.1 - 2.6e-05 24.1 6.7 2.6e-05 24.1 6.7 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORX89867.1 - 0.0002 21.4 3.6 0.0002 21.4 3.6 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 ORX89867.1 - 0.00025 21.4 43.0 0.017 15.6 6.6 4.8 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ORX89867.1 - 0.0036 17.5 14.2 0.0045 17.2 2.4 3.5 3 0 0 3 3 3 1 Zinc-finger containing family zf-C3HC4_3 PF13920.6 ORX89867.1 - 0.0093 15.8 7.9 0.0093 15.8 7.9 2.6 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX89867.1 - 0.0093 16.0 0.9 0.0093 16.0 0.9 3.3 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORX89867.1 - 0.015 15.2 6.7 0.015 15.2 6.7 2.6 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 ORX89867.1 - 0.035 14.4 0.9 0.035 14.4 0.9 2.8 3 0 0 3 3 3 0 zinc-ribbon zf-C3HC4 PF00097.25 ORX89867.1 - 0.11 12.4 21.3 0.093 12.6 15.2 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORX89867.1 - 6.8 6.6 12.8 0.25 11.2 5.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ABC_tran PF00005.27 ORX89868.1 - 8.6e-07 29.6 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORX89868.1 - 3.1e-05 23.5 0.1 3.6e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORX89868.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ribosomal_L13 PF00572.18 ORX89869.1 - 1.4e-54 183.6 0.1 2.1e-54 183.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Adaptin_N PF01602.20 ORX89870.1 - 6e-145 483.8 14.7 7.1e-145 483.5 14.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORX89870.1 - 2.5e-60 203.2 11.2 1.1e-58 197.9 1.3 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX89870.1 - 1.6e-18 66.8 4.3 2.8e-06 27.6 0.0 6.2 1 1 7 8 8 8 5 HEAT repeats HEAT PF02985.22 ORX89870.1 - 6.7e-10 38.4 6.9 0.033 14.4 0.0 7.7 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 ORX89870.1 - 1.9e-05 25.0 1.1 0.13 12.8 0.0 5.1 5 2 1 6 6 5 1 HEAT-like repeat Cnd3 PF12719.7 ORX89870.1 - 0.00014 21.2 5.3 0.0022 17.3 0.9 3.6 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 ORX89870.1 - 0.0013 18.9 9.2 2 8.7 0.4 5.1 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 ORX89870.1 - 0.013 15.5 8.1 2 8.6 0.0 5.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 ORX89870.1 - 0.017 15.1 1.7 13 5.9 0.0 4.5 3 2 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 ORX89870.1 - 0.022 14.4 1.3 1.1 8.8 0.0 3.6 4 1 1 5 5 5 0 CLASP N terminal Sec7_N PF12783.7 ORX89870.1 - 0.024 14.5 0.9 0.024 14.5 0.9 3.3 2 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UNC45-central PF11701.8 ORX89870.1 - 0.034 14.1 1.9 3.7 7.5 0.4 3.4 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 ORX89870.1 - 0.14 11.6 5.2 0.087 12.3 0.2 2.8 1 1 0 2 2 2 0 Armadillo-like GlutR_dimer PF00745.20 ORX89870.1 - 0.7 10.4 2.9 4 8.0 0.2 3.1 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ada3 PF10198.9 ORX89871.1 - 4.6e-35 120.6 9.5 4.6e-35 120.6 9.5 2.5 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 GPHR_N PF12537.8 ORX89871.1 - 0.036 14.2 0.7 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal ATR13 PF16829.5 ORX89871.1 - 0.083 13.3 1.5 3.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector RPAP3_C PF13877.6 ORX89872.1 - 3.7e-25 88.3 0.2 1.1e-24 86.8 0.2 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 ORX89872.1 - 7.4e-20 69.9 4.4 2.4e-08 33.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX89872.1 - 1.3e-15 56.2 4.8 7.9e-06 25.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX89872.1 - 2.9e-12 45.8 2.4 0.00043 20.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89872.1 - 4.7e-08 32.6 5.8 6.7e-07 28.9 0.3 3.4 2 1 1 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 ORX89872.1 - 8.9e-07 28.9 3.4 0.056 13.5 0.1 3.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 ORX89872.1 - 1.3e-05 25.2 0.2 0.0008 19.5 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX89872.1 - 1.4e-05 25.3 1.8 0.14 12.4 0.5 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89872.1 - 1.4e-05 25.5 2.2 0.00027 21.4 0.1 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89872.1 - 4.8e-05 23.9 0.0 0.00013 22.6 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX89872.1 - 8.8e-05 23.0 0.6 0.092 13.6 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX89872.1 - 0.00022 21.0 0.5 0.026 14.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX89872.1 - 0.0039 17.7 4.1 3.9 8.3 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX89872.1 - 0.0059 16.8 0.1 0.015 15.5 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORX89872.1 - 0.0061 16.9 2.9 0.012 16.0 0.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX89872.1 - 0.012 15.5 2.3 5.7 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 ORX89872.1 - 0.43 10.7 4.0 1.6 8.8 0.3 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Sec34 PF04136.15 ORX89873.1 - 3.8e-44 150.2 6.5 6.8e-44 149.3 4.8 2.5 2 0 0 2 2 2 1 Sec34-like family TAN PF11640.8 ORX89873.1 - 0.00082 19.5 0.0 0.0052 16.9 0.0 2.4 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair CLTH PF10607.9 ORX89873.1 - 0.016 15.1 0.0 0.089 12.7 0.0 2.3 2 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain FAT PF02259.23 ORX89873.1 - 0.068 12.4 3.9 0.27 10.4 0.3 2.7 3 0 0 3 3 3 0 FAT domain DUF5082 PF16888.5 ORX89873.1 - 0.073 13.4 0.8 12 6.2 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) I_LWEQ PF01608.17 ORX89873.1 - 0.46 10.7 2.2 1.3 9.2 1.0 2.4 2 0 0 2 2 2 0 I/LWEQ domain Myb_DNA-binding PF00249.31 ORX89874.1 - 4.6e-07 29.9 0.0 9.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORX89874.1 - 5.1e-07 29.4 9.9 7.8e-07 28.8 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 ORX89874.1 - 0.0012 19.0 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cytochrom_C PF00034.21 ORX89874.1 - 1.2 10.4 3.8 3.7 8.8 0.1 3.4 4 0 0 4 4 4 0 Cytochrome c CDC73_C PF05179.14 ORX89876.1 - 7e-52 175.3 1.7 7e-52 175.3 1.7 1.6 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 ORX89876.1 - 1.9e-23 83.3 6.1 4.3e-21 75.5 0.4 2.4 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal SnoaL_4 PF13577.6 ORX89876.1 - 0.038 14.1 0.2 0.07 13.3 0.2 1.3 1 0 0 1 1 1 0 SnoaL-like domain GREB1 PF15782.5 ORX89876.1 - 0.39 7.8 4.2 0.52 7.4 4.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Vps53_N PF04100.12 ORX89877.1 - 3.2e-109 365.4 16.6 3.2e-109 365.4 16.6 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 ORX89877.1 - 2.3e-05 23.9 8.8 2.3e-05 23.9 8.8 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 ORX89877.1 - 0.00023 21.1 0.9 0.0028 17.6 0.0 2.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 ORX89877.1 - 0.0032 16.4 7.4 0.0032 16.4 7.4 1.8 2 1 0 2 2 2 1 Spc7 kinetochore protein RecG_N PF17190.4 ORX89877.1 - 9.4 7.0 10.6 0.29 11.9 1.3 3.2 3 0 0 3 3 3 0 RecG N-terminal helical domain PNP_UDP_1 PF01048.20 ORX89878.1 - 4.7e-45 153.7 0.1 6.3e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Arrestin_C PF02752.22 ORX89879.1 - 2.5e-08 34.5 1.0 7.8e-07 29.6 0.1 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX89879.1 - 5.2e-05 23.3 0.1 0.00082 19.4 0.0 2.2 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PseudoU_synth_2 PF00849.22 ORX89882.1 - 1.2e-28 100.3 0.0 1.7e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ORX89882.1 - 0.0094 15.7 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 S4 domain DUF756 PF05506.12 ORX89883.1 - 0.061 14.2 0.2 0.078 13.9 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF756) Pro_isomerase PF00160.21 ORX89884.1 - 2.8e-52 177.2 0.5 5.4e-52 176.2 0.5 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 ORX89884.1 - 3.4e-06 27.2 0.0 9e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 U-box domain zf-NOSIP PF15906.5 ORX89884.1 - 5.4e-06 26.5 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 ORX89884.1 - 0.00016 21.1 0.1 0.00016 21.1 0.1 2.7 2 1 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.8 ORX89884.1 - 0.35 10.7 4.6 0.61 9.9 1.5 2.8 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Polysacc_deac_1 PF01522.21 ORX89885.1 - 1.4e-27 96.0 0.0 2.3e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX89885.1 - 5.8e-07 29.9 19.3 1.3e-06 28.7 19.3 1.7 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 ORX89885.1 - 0.0062 16.2 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) WD40 PF00400.32 ORX89886.1 - 1.7e-41 139.4 22.5 0.00018 22.2 0.3 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89886.1 - 7.2e-05 23.0 3.6 3.3 8.1 0.1 7.5 4 3 4 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX89886.1 - 0.003 16.6 0.6 0.16 10.9 0.0 3.3 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Ubie_methyltran PF01209.18 ORX89886.1 - 0.05 12.9 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family C2 PF00168.30 ORX89887.1 - 7.3e-14 51.9 0.1 9.9e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain Bestrophin PF01062.21 ORX89888.1 - 2.6e-49 168.2 0.9 3.2e-49 167.9 0.9 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4286 PF14114.6 ORX89889.1 - 1.2e-09 38.5 0.1 2.3e-09 37.6 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4286) ABM PF03992.16 ORX89889.1 - 1.8e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase HMG_box PF00505.19 ORX89890.1 - 1.8e-13 50.7 2.9 4.7e-13 49.4 2.9 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 ORX89890.1 - 2.6e-11 43.8 0.6 5.3e-11 42.8 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 ORX89890.1 - 3.2e-09 37.3 3.8 3.2e-09 37.3 3.8 2.2 1 1 1 2 2 2 1 HMG-box domain SAM_2 PF07647.17 ORX89890.1 - 1e-07 31.9 0.1 2.5e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORX89890.1 - 0.00064 19.7 0.0 0.0032 17.4 0.0 2.1 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) HTH_38 PF13936.6 ORX89890.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PP28 PF10252.9 ORX89890.1 - 0.19 12.2 4.6 0.31 11.5 4.6 1.4 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 FAM195 PF14799.6 ORX89890.1 - 0.44 10.9 4.2 0.67 10.3 3.5 1.7 1 1 1 2 2 2 0 FAM195 family AA_permease PF00324.21 ORX89891.1 - 1.4e-132 442.7 38.6 1.6e-132 442.5 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX89891.1 - 1.1e-39 136.4 38.9 1.1e-39 136.4 38.9 1.5 1 1 1 2 2 2 2 Amino acid permease ADP_ribosyl_GH PF03747.14 ORX89892.1 - 0.19 11.4 0.9 0.22 11.2 0.9 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase SlyX PF04102.12 ORX89893.1 - 1.6 9.4 4.1 3.4 8.3 0.7 2.9 3 0 0 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.9 ORX89893.1 - 4.3 7.5 6.7 5.6 7.2 0.3 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Med15_fungi PF05397.12 ORX89894.1 - 8.4e-31 106.6 1.4 8.4e-31 106.6 1.4 4.7 5 1 1 6 6 6 1 Mediator complex subunit 15 KIX_2 PF16987.5 ORX89894.1 - 9.4e-12 44.8 0.4 9.4e-12 44.8 0.4 3.3 2 0 0 2 2 2 1 KIX domain FapA PF03961.13 ORX89894.1 - 3.3 6.2 10.7 0.26 9.9 5.4 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Fer2_3 PF13085.6 ORX89895.1 - 1.4e-32 112.0 0.1 2.3e-32 111.2 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ORX89895.1 - 6.2e-10 39.5 6.8 6.2e-10 39.5 6.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORX89895.1 - 2.3e-06 28.0 12.6 3.8e-06 27.3 8.8 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORX89895.1 - 2.5e-06 27.5 3.8 2.5e-06 27.5 3.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ORX89895.1 - 0.00091 19.8 5.9 0.00091 19.8 5.9 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ORX89895.1 - 0.0015 18.5 4.8 0.0032 17.4 1.0 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.6 ORX89895.1 - 1.4 10.0 11.1 2 9.4 1.2 3.1 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 ORX89895.1 - 2.1 8.6 16.0 0.051 13.7 7.5 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.32 ORX89896.1 - 4.4e-14 52.7 0.0 0.069 14.0 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX89896.1 - 2.3e-10 40.6 0.0 0.29 11.5 0.0 5.7 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORX89896.1 - 0.00012 20.7 0.2 0.00096 17.8 0.1 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 ORX89896.1 - 0.0048 16.8 0.1 1.8 8.6 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 ORX89896.1 - 0.017 13.9 0.2 0.049 12.4 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4394 PF14339.6 ORX89896.1 - 0.032 13.6 0.1 0.6 9.4 0.0 2.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4394) Pirin PF02678.16 ORX89897.1 - 1.8e-31 108.3 0.1 3.8e-31 107.3 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORX89897.1 - 4.7e-30 104.0 0.0 8.2e-29 100.0 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORX89897.1 - 0.0042 16.8 3.2 0.041 13.6 1.4 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 ORX89897.1 - 0.14 11.9 0.4 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) TfoX_C PF04994.13 ORX89898.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 TfoX C-terminal domain YlbD_coat PF14071.6 ORX89898.1 - 0.068 13.4 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative coat protein CBAH PF02275.18 ORX89900.1 - 0.023 14.4 0.4 0.03 14.0 0.4 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Kelch_3 PF13415.6 ORX89901.1 - 0.053 13.8 0.1 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Helicase_C PF00271.31 ORX89902.1 - 0.00011 22.5 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PARP PF00644.20 ORX89903.1 - 8.1e-57 192.0 0.0 2.4e-56 190.4 0.0 1.8 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 ORX89903.1 - 5.5e-22 77.6 1.6 1.3e-21 76.5 1.6 1.6 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 ORX89903.1 - 1.3e-19 70.6 0.1 2.9e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_2 PF12796.7 ORX89903.1 - 1.1e-07 32.3 0.3 0.00049 20.6 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) zf-CCHH PF10283.9 ORX89903.1 - 7.6e-06 25.8 5.2 1.8e-05 24.6 5.2 1.6 1 0 0 1 1 1 1 PBZ domain zf-CRD PF17979.1 ORX89903.1 - 0.00049 20.2 0.7 0.0019 18.3 0.1 2.4 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions Ank_3 PF13606.6 ORX89903.1 - 0.0014 19.0 0.2 0.53 11.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 ORX89903.1 - 0.0046 17.2 0.6 1.1 9.7 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX89903.1 - 0.036 14.6 0.1 20 5.9 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 ORX89903.1 - 0.08 13.4 0.0 0.46 11.0 0.0 2.5 1 0 0 1 1 1 0 Ankyrin repeat Peptidase_Mx PF15887.5 ORX89903.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Humanin PF15040.6 ORX89903.1 - 0.12 11.8 1.1 0.25 10.8 1.1 1.4 1 0 0 1 1 1 0 Humanin family zf-C2H2 PF00096.26 ORX89904.1 - 9.5e-17 60.4 21.0 2.8e-06 27.5 0.3 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX89904.1 - 1.2e-16 60.3 13.3 3.2e-06 27.3 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX89904.1 - 6e-08 32.9 20.9 0.0052 17.5 0.3 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX89904.1 - 7.2e-06 26.2 2.7 0.0018 18.6 3.0 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORX89904.1 - 4.9e-05 23.9 4.4 0.29 11.8 0.1 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX89904.1 - 0.0003 21.4 7.0 0.0037 17.9 0.5 2.9 1 1 2 3 3 3 2 TRAF-type zinc finger CHORD PF04968.12 ORX89904.1 - 0.018 15.7 7.2 2.1 9.2 0.1 3.3 1 1 2 3 3 3 0 CHORD JAB PF01398.21 ORX89905.1 - 1.1e-33 115.6 0.4 1.9e-33 115.0 0.4 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ORX89905.1 - 4.6e-29 101.2 1.3 8.9e-29 100.3 1.3 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ORX89905.1 - 0.0049 16.6 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PI3_PI4_kinase PF00454.27 ORX89906.1 - 2.2e-56 191.5 0.0 4.8e-56 190.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORX89906.1 - 2e-48 165.4 6.3 4.3e-48 164.3 6.3 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 ORX89906.1 - 2.7e-29 101.1 1.1 7.4e-28 96.5 0.1 3.4 2 1 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 ORX89906.1 - 5.2e-13 48.6 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 ORX89906.1 - 0.0038 17.2 6.2 0.54 10.1 0.2 3.9 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) HEAT PF02985.22 ORX89906.1 - 0.015 15.5 0.1 3.5 8.1 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Clathrin PF00637.20 ORX89906.1 - 0.016 15.1 0.2 0.23 11.3 0.1 2.8 2 0 0 2 2 2 0 Region in Clathrin and VPS Phage_tail_U PF06141.11 ORX89906.1 - 0.03 14.7 0.1 0.1 13.0 0.1 1.9 1 0 0 1 1 1 0 Phage minor tail protein U Ripply PF14998.6 ORX89906.1 - 0.37 11.5 1.9 2.9 8.6 0.4 3.0 3 0 0 3 3 3 0 Transcription Regulator Vac14_Fab1_bd PF12755.7 ORX89906.1 - 1.5 9.5 5.6 3.9 8.1 0.2 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region CTNNBL PF08216.11 ORX89907.1 - 1.6e-37 127.8 1.1 6.1e-37 126.0 1.1 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Peptidase_M16 PF00675.20 ORX89907.1 - 0.037 14.0 1.5 0.1 12.6 0.5 2.3 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Arm_3 PF16186.5 ORX89907.1 - 0.075 12.6 2.3 0.12 12.0 0.6 2.3 2 0 0 2 2 2 0 Atypical Arm repeat RIH_assoc PF08454.11 ORX89907.1 - 0.1 12.5 0.7 1.2 9.0 0.2 3.1 2 1 0 2 2 2 0 RyR and IP3R Homology associated V-ATPase_H_C PF11698.8 ORX89907.1 - 6.1 7.0 6.7 11 6.2 0.0 3.9 4 1 1 5 5 5 0 V-ATPase subunit H HMMR_C PF15908.5 ORX89908.1 - 4.6e-10 40.0 14.3 4.6e-10 40.0 14.3 2.9 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor C-terminal Bacillus_HBL PF05791.11 ORX89908.1 - 0.016 15.1 4.7 0.016 15.1 4.7 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TetR PF13972.6 ORX89908.1 - 0.07 12.8 7.1 0.19 11.5 7.1 1.7 1 0 0 1 1 1 0 Bacterial transcriptional repressor Shugoshin_N PF07558.11 ORX89908.1 - 0.074 12.9 9.1 1 9.3 3.5 3.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Sas6_CC PF18594.1 ORX89908.1 - 0.093 12.5 4.5 0.28 11.0 0.4 3.1 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Glyco_transf_18 PF15024.6 ORX89908.1 - 0.2 10.2 5.3 0.32 9.5 5.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 18 PepSY_TM_like_2 PF16357.5 ORX89908.1 - 4.6 7.2 10.3 1.2 9.1 5.8 2.0 1 1 1 2 2 2 0 Putative PepSY_TM-like Pkinase PF00069.25 ORX89909.1 - 3.3e-49 167.6 0.0 4.4e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX89909.1 - 3.5e-25 88.8 0.0 4.9e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX89909.1 - 0.0013 18.2 1.8 0.0032 16.9 1.8 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX89909.1 - 0.0033 16.8 0.0 0.01 15.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like DUF1601 PF07671.11 ORX89909.1 - 0.065 13.1 0.2 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) UBD PF16455.5 ORX89910.1 - 1.4e-29 102.3 0.0 2.1e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 ORX89910.1 - 9.2e-10 38.1 0.1 1.6e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX89910.1 - 4.5e-05 23.2 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORX89910.1 - 0.007 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORX89910.1 - 0.02 15.4 0.1 0.038 14.5 0.1 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Cons_hypoth698 PF03601.14 ORX89911.1 - 5.7e-36 124.0 14.8 2.6e-35 121.8 14.8 1.8 1 1 0 1 1 1 1 Conserved hypothetical protein 698 Glt_symporter PF03616.14 ORX89911.1 - 0.11 11.1 13.5 0.014 14.1 1.8 2.8 2 1 1 3 3 3 0 Sodium/glutamate symporter BTB_2 PF02214.22 ORX89912.1 - 2.4e-13 50.3 0.0 4.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 ORX89912.1 - 2.1e-11 43.9 0.0 4.4e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain RNA_pol_Rpb2_6 PF00562.28 ORX89914.1 - 1.7e-06 27.3 0.3 3e-06 26.6 0.3 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Mg296 PF09644.10 ORX89914.1 - 0.08 13.1 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Mg296 protein RNA_pol_Rpb2_6 PF00562.28 ORX89915.1 - 7.7e-24 84.5 0.1 8.8e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 DUF3684 PF12449.8 ORX89916.1 - 4.3e-226 753.3 0.0 1.7e-140 469.9 0.0 3.0 2 1 1 3 3 3 3 Protein of unknown function (DUF3684) CUE PF02845.16 ORX89916.1 - 0.0054 16.4 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 CUE domain WLM PF08325.10 ORX89916.1 - 0.14 12.2 1.0 0.26 11.4 1.0 1.3 1 0 0 1 1 1 0 WLM domain HATPase_c_3 PF13589.6 ORX89916.1 - 0.24 11.2 0.0 9 6.1 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ku PF02735.16 ORX89917.1 - 2.2e-30 105.9 0.0 3.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORX89917.1 - 2.4e-15 56.9 0.1 5.5e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 ORX89917.1 - 1.7e-05 25.1 0.1 3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 ORX89917.1 - 2.4e-05 24.9 0.6 7.5e-05 23.4 0.6 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm DUF5102 PF17104.5 ORX89918.1 - 7.4e-17 62.3 51.5 3.3e-11 43.8 0.1 5.1 2 1 2 4 4 4 2 Domain of unknown function (DUF5102) Peptidase_M16 PF00675.20 ORX89919.1 - 1.2e-54 184.4 0.2 1.2e-54 184.4 0.2 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORX89919.1 - 4.7e-40 137.5 0.0 1.6e-39 135.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF913 PF06025.12 ORX89920.1 - 8.1e-106 354.1 0.3 8.1e-106 354.1 0.3 6.7 8 1 0 8 8 8 3 Domain of Unknown Function (DUF913) HECT PF00632.25 ORX89920.1 - 2.4e-97 326.2 0.1 4.3e-97 325.3 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 ORX89920.1 - 3.1e-59 201.2 0.3 3.1e-59 201.2 0.3 5.1 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) UBM PF14377.6 ORX89920.1 - 6.1e-29 98.6 23.0 4.8e-11 41.7 0.8 4.2 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 ORX89920.1 - 5e-07 29.5 0.0 1.4e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain FOXO_KIX_bdg PF16675.5 ORX89920.1 - 0.028 14.7 0.0 0.2 11.9 0.0 2.6 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 DUF908 PF06012.12 ORX89921.1 - 5.7e-18 65.5 5.8 7.4e-18 65.1 5.8 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) PhoU_div PF01865.16 ORX89921.1 - 0.032 13.6 0.0 0.097 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF47 Lipase_3 PF01764.25 ORX89922.1 - 1.2e-07 31.7 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PRP1_N PF06424.12 ORX89923.1 - 7.6e-55 185.4 5.4 2e-54 184.0 5.4 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 ORX89923.1 - 2.1e-27 93.5 23.0 0.0019 18.9 0.0 13.7 5 3 9 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 ORX89923.1 - 3.2e-20 72.4 4.1 1.9e-05 25.1 0.1 8.2 7 2 1 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORX89923.1 - 2.6e-11 42.7 4.3 0.043 13.9 0.0 10.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX89923.1 - 1.8e-10 41.3 2.5 0.0074 16.9 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX89923.1 - 1.1e-08 34.9 2.9 0.2 12.1 0.0 8.1 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORX89923.1 - 1.1e-06 28.5 6.8 0.028 14.1 0.8 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 ORX89923.1 - 5.4e-06 26.2 6.2 0.11 12.8 0.0 7.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX89923.1 - 1.7e-05 24.4 0.0 0.035 14.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX89923.1 - 4.3e-05 23.1 0.7 4.1 7.2 0.0 7.2 6 2 3 9 9 9 1 TPR repeat TPR_6 PF13174.6 ORX89923.1 - 0.0022 18.5 5.8 34 5.3 0.0 7.7 10 0 0 10 10 7 0 Tetratricopeptide repeat NARP1 PF12569.8 ORX89923.1 - 0.0028 16.7 10.8 0.0045 15.9 0.0 5.1 5 1 2 7 7 7 2 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 ORX89923.1 - 0.0084 14.9 1.1 3.1 6.4 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3808) Suf PF05843.14 ORX89923.1 - 0.015 15.3 7.7 0.3 11.0 0.0 4.8 5 0 0 5 5 5 0 Suppressor of forked protein (Suf) F-box-like_2 PF13013.6 ORX89923.1 - 0.081 12.9 0.3 25 4.9 0.0 3.6 4 0 0 4 4 4 0 F-box-like domain FAT PF02259.23 ORX89923.1 - 2.8 7.1 18.8 0.31 10.2 1.1 4.2 2 1 1 4 4 4 0 FAT domain ECH_1 PF00378.20 ORX89924.1 - 4.7e-51 173.5 0.0 8.9e-51 172.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX89924.1 - 6.4e-33 114.6 0.0 4.2e-30 105.4 0.0 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rpr2 PF04032.16 ORX89926.1 - 5.8e-19 68.2 0.3 1e-18 67.4 0.3 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_4 PF13717.6 ORX89926.1 - 0.048 13.6 0.4 0.048 13.6 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF5505 PF17610.2 ORX89926.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5505) SWIRM-assoc_2 PF16496.5 ORX89927.1 - 9.1e-16 57.7 0.0 1e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal LysR_substrate PF03466.20 ORX89927.1 - 0.02 14.3 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 LysR substrate binding domain SWIRM PF04433.17 ORX89928.1 - 6.2e-31 106.6 0.1 1.3e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ORX89928.1 - 2.7e-29 100.9 4.5 4.8e-29 100.1 4.5 1.4 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ORX89928.1 - 9.1e-13 48.2 0.2 1.6e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORX89928.1 - 3.2e-09 36.4 4.6 5.6e-09 35.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 ORX89928.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF919 PF06034.11 ORX89928.1 - 0.022 14.6 5.8 0.044 13.6 5.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Myb_DNA-bind_7 PF15963.5 ORX89928.1 - 0.025 14.4 2.8 0.058 13.3 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Zn_ribbon_2 PF12674.7 ORX89928.1 - 0.038 14.7 1.5 0.13 12.9 1.5 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain SWIRM-assoc_3 PF16498.5 ORX89928.1 - 0.081 13.2 0.2 0.081 13.2 0.2 2.0 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal Bap31 PF05529.12 ORX89929.1 - 1.7e-36 125.0 6.8 2.6e-36 124.5 6.8 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ORX89929.1 - 0.12 12.4 3.4 0.2 11.7 3.4 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Dynactin_p62 PF05502.13 ORX89930.1 - 3.2e-74 250.4 29.9 4.3e-39 134.6 16.5 2.6 1 1 1 2 2 2 2 Dynactin p62 family BTB PF00651.31 ORX89931.1 - 1.3e-10 41.5 0.0 3.3e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Glyco_hydro_46 PF01374.18 ORX89932.1 - 7.5e-32 110.7 0.0 8.9e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 ORX89933.1 - 7.5e-32 110.7 0.0 8.9e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Ldh_1_N PF00056.23 ORX89934.1 - 2.1e-48 164.0 0.2 6.4e-48 162.4 0.2 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX89934.1 - 5.2e-36 124.1 0.1 1.8e-34 119.1 0.1 2.2 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 ORX89934.1 - 0.0014 18.2 1.1 0.081 12.5 0.2 2.9 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 ORX89934.1 - 0.019 14.0 0.0 0.058 12.4 0.0 1.8 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 ORX89934.1 - 0.057 12.7 0.1 0.49 9.7 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 ORX89935.1 - 5e-43 146.6 0.7 7.6e-43 146.0 0.7 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX89935.1 - 3.3e-39 134.5 0.0 4.7e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain THF_DHG_CYH_C PF02882.19 ORX89935.1 - 0.00058 19.2 0.6 0.013 14.8 0.1 2.7 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 ORX89935.1 - 0.0065 16.0 3.8 0.11 12.1 0.6 2.9 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 ORX89935.1 - 0.012 14.7 0.0 0.053 12.5 0.0 2.0 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORX89935.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NS3_envE PF02723.14 ORX89941.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E PDCD2_C PF04194.13 ORX89942.1 - 1.1e-40 139.6 7.1 9.8e-39 133.2 0.9 3.0 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 ORX89942.1 - 1.2e-06 28.5 10.5 1.2e-06 28.5 10.5 3.2 3 0 0 3 3 3 1 MYND finger PPI_Ypi1 PF07491.11 ORX89943.1 - 1.5e-22 79.2 1.0 3.5e-22 78.0 1.0 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor Utp11 PF03998.13 ORX89944.1 - 2.6e-76 256.8 24.8 3e-76 256.6 24.8 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 ORX89944.1 - 6.5 6.0 8.3 0.65 9.3 1.4 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 EMC1_C PF07774.13 ORX89945.1 - 2e-72 243.3 0.0 2.7e-71 239.7 0.0 2.6 3 0 0 3 3 3 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 ORX89945.1 - 3.1e-14 53.1 1.2 8.6e-10 38.6 1.2 2.7 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 ORX89945.1 - 0.0032 17.3 3.1 0.21 11.6 0.0 4.2 5 0 0 5 5 5 1 PQQ enzyme repeat PEX11 PF05648.14 ORX89946.1 - 9e-57 192.1 6.4 1e-56 191.9 6.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SieB PF14163.6 ORX89946.1 - 0.23 11.0 2.9 0.5 9.8 2.8 1.7 1 1 1 2 2 2 0 Super-infection exclusion protein B Med4 PF10018.9 ORX89946.1 - 0.48 10.1 2.6 0.8 9.4 1.9 1.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 G6PD_C PF02781.16 ORX89947.1 - 4.2e-116 387.2 0.0 1.4e-115 385.5 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORX89947.1 - 5.2e-59 199.8 0.1 8.1e-59 199.2 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ion_trans PF00520.31 ORX89948.1 - 1.7e-12 47.1 22.5 1.7e-12 47.1 22.5 2.2 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 ORX89948.1 - 0.00088 18.1 18.9 0.015 14.0 18.9 2.2 1 1 0 1 1 1 1 Polycystin cation channel Zip PF02535.22 ORX89949.1 - 5e-52 177.2 19.3 1.9e-51 175.2 19.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2486 PF10667.9 ORX89950.1 - 0.17 12.1 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF3472 PF11958.8 ORX89951.1 - 1e-20 74.9 0.7 1.4e-20 74.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX89951.1 - 8.4e-09 35.6 0.2 1.4e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) Amidohydro_1 PF01979.20 ORX89958.1 - 2.6e-73 247.3 1.6 3.8e-73 246.8 1.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORX89958.1 - 9.4e-57 190.6 2.7 2.1e-56 189.4 2.7 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 ORX89958.1 - 5e-39 132.6 0.2 1.1e-38 131.6 0.2 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 ORX89958.1 - 2.2e-38 130.2 0.0 4.2e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 ORX89958.1 - 4.1e-06 26.5 0.9 1.5e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family DUF1150 PF06620.11 ORX89959.1 - 0.044 13.9 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) DUF3291 PF11695.8 ORX89960.1 - 2e-57 192.8 0.2 2.3e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) DUF3291 PF11695.8 ORX89961.1 - 2e-57 192.8 0.2 2.2e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) Yip1 PF04893.17 ORX89964.1 - 9.3e-09 35.2 13.5 9.3e-09 35.2 13.5 1.9 1 1 1 2 2 2 1 Yip1 domain GyrB_insert PF18053.1 ORX89965.1 - 0.0064 16.4 0.5 0.0069 16.3 0.5 1.0 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain FliX PF10768.9 ORX89965.1 - 0.12 12.9 1.6 0.14 12.6 1.6 1.2 1 0 0 1 1 1 0 Class II flagellar assembly regulator TALPID3 PF15324.6 ORX89965.1 - 0.17 9.5 2.3 0.17 9.5 2.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target zf-RING_5 PF14634.6 ORX89966.1 - 3.1e-07 30.2 11.9 5.4e-07 29.5 11.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORX89966.1 - 2.7e-05 23.9 7.3 5.2e-05 23.0 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORX89966.1 - 0.00014 22.1 10.8 0.00027 21.2 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX89966.1 - 0.00015 21.5 5.5 0.00035 20.4 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX89966.1 - 0.00049 19.9 9.7 0.00085 19.1 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORX89966.1 - 0.002 17.9 6.3 0.0037 17.1 6.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORX89966.1 - 0.008 16.0 3.4 0.016 15.0 3.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ORX89966.1 - 0.044 14.1 6.1 0.076 13.3 6.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 ORX89966.1 - 0.054 13.6 8.6 0.063 13.4 7.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 ORX89966.1 - 0.058 13.3 9.1 0.11 12.4 9.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 ORX89966.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein zf-P11 PF03854.14 ORX89966.1 - 0.12 12.0 3.9 0.19 11.4 3.5 1.6 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 ORX89966.1 - 0.17 12.1 5.6 0.37 11.0 5.6 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 ORX89966.1 - 0.61 10.2 7.7 0.45 10.6 5.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Mad3_BUB1_I PF08311.12 ORX89967.1 - 8.2e-34 116.3 1.5 2e-33 115.0 1.5 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 ORX89967.1 - 0.00012 22.2 1.0 0.00073 19.7 0.1 2.8 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 ORX89967.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein LMBR1 PF04791.16 ORX89968.1 - 6e-81 272.9 4.1 6.9e-81 272.7 4.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Cofilin_ADF PF00241.20 ORX89969.1 - 1.6e-14 53.7 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HRDC PF00570.23 ORX89971.1 - 0.088 12.8 0.2 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 HRDC domain DUF4290 PF14123.6 ORX89971.1 - 0.18 11.3 8.4 1.9 8.0 6.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4290) TRAF_BIRC3_bd PF16673.5 ORX89971.1 - 1.3 8.9 3.9 7.3 6.5 0.3 3.4 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain MS_channel PF00924.18 ORX89972.1 - 1.2e-19 70.6 0.0 2.3e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF624 PF04854.14 ORX89972.1 - 0.11 12.6 1.5 10 6.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF624 DMT_YdcZ PF04657.13 ORX89973.1 - 3e-28 98.9 8.0 3.5e-28 98.6 8.0 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ QSOX_Trx1 PF18108.1 ORX89974.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 QSOX Trx-like domain MIP PF00230.20 ORX89975.1 - 1.1e-29 103.7 14.2 1.4e-29 103.4 14.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ras PF00071.22 ORX89976.1 - 1.5e-50 171.0 0.0 1.7e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89976.1 - 2.9e-20 72.7 0.0 4.7e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89976.1 - 6.6e-08 32.2 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX89976.1 - 3.4e-05 23.5 0.1 0.00011 21.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORX89976.1 - 0.00039 20.0 0.0 0.075 12.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORX89976.1 - 0.00072 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORX89976.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORX89976.1 - 0.066 13.1 0.0 9.6 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 ORX89976.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 ORX89977.1 - 1.5e-50 171.0 0.0 1.7e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX89977.1 - 2.6e-20 72.8 0.0 4.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX89977.1 - 3.4e-08 33.2 0.0 3.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX89977.1 - 2.8e-05 23.8 0.1 0.00012 21.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORX89977.1 - 0.00038 20.0 0.0 0.075 12.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORX89977.1 - 0.00086 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORX89977.1 - 0.0015 18.0 0.0 0.0034 16.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORX89977.1 - 0.07 13.0 0.0 10 6.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SHMT PF00464.19 ORX89978.1 - 1.6e-182 606.6 0.0 1.8e-182 606.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 ORX89978.1 - 1.9e-08 33.9 0.0 1.2e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORX89978.1 - 1.7e-07 30.7 0.0 3.2e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.6 ORX89978.1 - 0.039 14.2 3.2 0.1 12.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4142) DegT_DnrJ_EryC1 PF01041.17 ORX89978.1 - 0.055 12.8 0.0 0.095 12.0 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Abhydrolase_1 PF00561.20 ORX89979.1 - 7.4e-12 45.5 0.0 9e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX89979.1 - 9.6e-05 23.1 0.0 0.00016 22.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX89979.1 - 0.0044 16.3 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ORX89979.1 - 0.0084 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family RRM_1 PF00076.22 ORX89985.1 - 1.1e-22 79.6 0.5 1e-10 41.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX89985.1 - 0.0072 16.3 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 ORX89985.1 - 0.15 12.0 0.0 0.9 9.5 0.0 2.3 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Med12 PF09497.10 ORX89986.1 - 6e-20 71.3 0.0 1.8e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 ORX89986.1 - 3e-14 52.8 0.0 6.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain F_bP_aldolase PF01116.20 ORX89987.1 - 6.3e-92 308.0 0.0 7.1e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II HARE-HTH PF05066.13 ORX89989.1 - 0.19 12.2 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Vg_Tdu PF07545.14 ORX89989.1 - 0.29 10.9 2.4 4.8 7.0 0.3 2.5 2 0 0 2 2 2 0 Vestigial/Tondu family bZIP_1 PF00170.21 ORX89991.1 - 1.4e-06 28.3 11.2 3e-06 27.2 11.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX89991.1 - 1.7e-06 28.0 13.8 2.9e-06 27.3 13.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX89991.1 - 6.1e-05 23.5 5.3 6.1e-05 23.5 5.3 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF2353 PF09789.9 ORX89991.1 - 0.066 12.6 2.0 0.084 12.2 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CsbD PF05532.12 ORX89992.1 - 0.00074 19.4 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 CsbD-like HAMP PF00672.25 ORX89993.1 - 1.8e-98 322.8 19.7 8e-08 32.5 0.0 14.6 14 0 0 14 14 13 12 HAMP domain HATPase_c PF02518.26 ORX89993.1 - 7.2e-30 103.8 0.3 2.4e-29 102.1 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX89993.1 - 2.8e-27 95.1 1.5 8.7e-26 90.3 0.3 3.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORX89993.1 - 1.3e-16 60.4 0.4 1.2e-15 57.3 0.4 2.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HMG_box PF00505.19 ORX89993.1 - 6e-13 49.0 0.4 42 4.7 0.0 10.5 11 0 0 11 11 11 0 HMG (high mobility group) box DUF4279 PF14106.6 ORX89993.1 - 3.4e-11 43.4 0.0 70 3.7 0.0 10.8 11 0 0 11 11 11 0 Domain of unknown function (DUF4279) HTH_6 PF01418.17 ORX89993.1 - 1.8e-10 40.7 0.1 42 4.2 0.0 10.5 10 0 0 10 10 10 0 Helix-turn-helix domain, rpiR family IL32 PF15225.6 ORX89993.1 - 3.8e-09 36.8 0.1 14 6.2 0.0 10.6 11 1 0 11 11 10 0 Interleukin 32 GatB_Yqey PF02637.18 ORX89993.1 - 2.5e-07 30.7 34.9 1.5 8.7 0.0 11.1 9 2 0 11 11 11 2 GatB domain Focal_AT PF03623.13 ORX89993.1 - 2.6e-07 30.7 33.8 3 7.8 0.1 12.1 1 1 8 12 12 12 3 Focal adhesion targeting region WXG100 PF06013.12 ORX89993.1 - 8e-07 29.2 51.5 1.4 9.2 0.2 14.0 13 3 4 17 17 14 4 Proteins of 100 residues with WXG SpoIIID PF12116.8 ORX89993.1 - 9.9e-07 28.8 20.8 15 5.8 0.0 10.7 11 0 0 11 11 11 0 Stage III sporulation protein D CENP-F_leu_zip PF10473.9 ORX89993.1 - 1.8e-05 24.8 39.0 9.2 6.3 0.0 12.9 13 0 0 13 13 13 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1759 PF03564.15 ORX89993.1 - 2.7e-05 24.1 15.8 16 5.4 0.0 9.9 11 0 0 11 11 11 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 ORX89993.1 - 3.8e-05 23.8 98.3 0.13 12.3 5.9 13.0 3 2 9 12 12 11 5 Baculovirus polyhedron envelope protein, PEP, C terminus GhoS PF11080.8 ORX89993.1 - 3.9e-05 23.5 30.8 2.2 8.3 0.3 10.7 10 1 0 11 11 11 1 Endoribonuclease GhoS VBS PF08913.10 ORX89993.1 - 5.3e-05 23.7 45.9 12 6.4 0.1 11.2 10 1 1 11 11 11 0 Vinculin Binding Site GLE1 PF07817.13 ORX89993.1 - 0.0001 21.6 27.2 9.2 5.4 0.1 10.4 1 1 10 11 11 11 0 GLE1-like protein Abhydrolase_8 PF06259.12 ORX89993.1 - 0.00067 19.3 66.7 3.2 7.4 0.8 11.4 8 3 3 11 11 11 4 Alpha/beta hydrolase ApoLp-III PF07464.11 ORX89993.1 - 0.00096 19.3 67.1 0.25 11.4 0.6 11.7 2 2 10 12 12 12 7 Apolipophorin-III precursor (apoLp-III) DUF1843 PF08898.10 ORX89993.1 - 0.0018 18.7 27.8 23 5.6 0.0 11.0 13 0 0 13 13 11 0 Domain of unknown function (DUF1843) DUF2294 PF10057.9 ORX89993.1 - 0.016 15.3 0.2 0.43 10.7 0.3 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Peptidase_C31 PF05410.13 ORX89993.1 - 0.65 10.1 6.0 75 3.5 0.0 6.7 10 0 0 10 10 10 0 Porcine arterivirus-type cysteine proteinase alpha PKI PF02827.16 ORX89993.1 - 0.88 9.8 6.7 4.7e+02 1.1 0.0 6.9 8 0 0 8 8 8 0 cAMP-dependent protein kinase inhibitor Fib_alpha PF08702.10 ORX89993.1 - 3.8 7.7 46.6 7.9 6.7 0.2 11.5 12 2 1 13 13 13 0 Fibrinogen alpha/beta chain family OspD PF03207.13 ORX89993.1 - 3.9 6.8 69.3 0.12 11.7 0.8 10.8 7 3 0 10 10 10 0 Borrelia outer surface protein D (OspD) RAP-1 PF03085.15 ORX89993.1 - 8.8 5.9 28.7 7.5 6.2 0.0 7.5 8 0 0 8 8 8 0 Rhoptry-associated protein 1 (RAP-1) Pmp3 PF01679.17 ORX89994.1 - 2.2e-22 79.0 5.3 2.5e-22 78.8 5.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MscL PF01741.18 ORX89995.1 - 2.5e-27 95.6 0.5 3.1e-27 95.3 0.5 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FAM76 PF16046.5 ORX89995.1 - 0.017 14.5 1.9 0.022 14.1 1.9 1.1 1 0 0 1 1 1 0 FAM76 protein C1_1 PF00130.22 ORX89995.1 - 0.059 13.3 1.6 0.093 12.6 1.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.15 ORX89995.1 - 3.9 7.6 8.4 3.8 7.6 3.9 2.5 2 1 1 3 3 3 0 BED zinc finger Cyclin_N PF00134.23 ORX89996.1 - 1.1e-44 151.3 0.1 2.4e-44 150.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX89996.1 - 5.3e-30 104.0 2.3 7.4e-30 103.5 1.4 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain MnmE_helical PF12631.7 ORX89997.1 - 3.1e-49 167.9 0.8 4.2e-49 167.5 0.8 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 ORX89997.1 - 1.6e-37 128.3 0.0 3.4e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 ORX89997.1 - 4.2e-20 71.9 0.2 7.7e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX89997.1 - 6.6e-10 38.7 0.1 1.2e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORX89997.1 - 2.6e-05 24.4 0.0 7.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Arf PF00025.21 ORX89997.1 - 0.00056 19.4 0.1 0.0035 16.8 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX89997.1 - 0.00061 19.7 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 ORX89997.1 - 0.0073 15.9 0.1 0.051 13.2 0.1 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.16 ORX89998.1 - 3.6e-39 134.7 33.8 4.5e-39 134.4 33.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX89998.1 - 9.4e-06 25.2 2.7 9.4e-06 25.2 2.7 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Acetyltransf_1 PF00583.25 ORX89999.1 - 1.5e-09 38.1 0.0 1.9e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX89999.1 - 3.6e-08 33.4 0.0 1.4e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX89999.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORX89999.1 - 0.012 16.3 0.0 0.015 16.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PhyH PF05721.13 ORX90000.1 - 1.7e-49 168.9 0.0 2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GAPES1 PF17155.4 ORX90000.1 - 0.14 11.5 0.0 0.6 9.4 0.0 1.8 1 1 1 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Zn_clus PF00172.18 ORX90001.1 - 1.4e-12 47.5 11.8 2.2e-12 46.9 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX90001.1 - 0.00041 19.5 1.0 0.00085 18.4 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain HAP1_N PF04849.13 ORX90001.1 - 0.061 12.5 2.9 0.085 12.1 2.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1943 PF09172.11 ORX90001.1 - 0.13 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MFS_1 PF07690.16 ORX90002.1 - 3.3e-27 95.3 25.5 7e-14 51.5 6.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily 2OG-FeII_Oxy_2 PF13532.6 ORX90003.1 - 1.6e-17 64.3 0.0 2.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GPI-anchored PF10342.9 ORX90004.1 - 3.5e-11 43.7 0.0 4.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribonuc_L-PSP PF01042.21 ORX90005.1 - 7.6e-47 158.3 0.2 8.6e-47 158.1 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_L5_C PF00673.21 ORX90006.1 - 1.2e-22 79.9 0.0 1.7e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORX90006.1 - 3e-22 78.7 0.0 1.9e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 ORX90006.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Zona_pellucida PF00100.23 ORX90006.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain NDUF_B7 PF05676.13 ORX90007.1 - 1.3e-31 108.1 3.6 1.7e-31 107.7 3.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ORX90007.1 - 0.025 14.6 3.7 0.036 14.1 3.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like RabGAP-TBC PF00566.18 ORX90008.1 - 3e-22 79.3 0.2 4.9e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_47 PF01532.20 ORX90009.1 - 1.5e-159 531.8 0.1 1.7e-159 531.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF390 PF04094.14 ORX90010.1 - 0.29 9.4 0.3 0.4 8.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4955 PF16315.5 ORX90011.1 - 0.00022 21.5 0.1 0.0006 20.0 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4955) Arf PF00025.21 ORX90012.1 - 3.9e-77 257.6 0.0 4.5e-77 257.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX90012.1 - 2.1e-15 57.0 0.1 2.7e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX90012.1 - 5.2e-14 52.2 0.0 5.6e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORX90012.1 - 8.4e-13 48.2 0.0 1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORX90012.1 - 1.6e-12 47.3 1.1 4.6e-08 32.6 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORX90012.1 - 2.1e-09 37.1 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX90012.1 - 0.00022 21.3 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX90012.1 - 0.003 16.9 0.1 0.0046 16.3 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MIP PF00230.20 ORX90013.1 - 3.7e-52 177.3 9.1 4.5e-52 177.0 9.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein dDENN PF03455.19 ORX90013.1 - 0.12 12.3 0.9 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 dDENN domain Vut_1 PF02592.15 ORX90013.1 - 0.89 9.9 7.8 1.5 9.2 6.3 2.1 2 1 1 3 3 3 0 Putative vitamin uptake transporter Velvet PF11754.8 ORX90014.1 - 6.4e-37 127.8 0.7 8.3e-37 127.5 0.7 1.0 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.16 ORX90015.1 - 0.012 14.6 0.1 0.013 14.4 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.16 ORX90016.1 - 4.2e-18 65.4 31.7 4.8e-17 61.9 31.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily RGS PF00615.19 ORX90018.1 - 2.8e-13 50.2 5.8 4.1e-13 49.6 5.8 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX90018.1 - 0.39 10.4 19.7 1.6 8.4 18.1 2.5 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Sugar_tr PF00083.24 ORX90019.1 - 1.5e-29 103.2 8.1 1.8e-29 102.9 8.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 ORX90020.1 - 2.1e-56 191.7 21.9 2.5e-56 191.4 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90020.1 - 1.8e-26 92.9 24.4 1.8e-26 92.9 24.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX90020.1 - 1e-06 28.4 3.6 1e-06 28.4 3.6 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Git3 PF11710.8 ORX90021.1 - 2.7e-16 60.0 4.8 5.6e-16 58.9 4.8 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 ORX90021.1 - 1.8e-08 33.9 3.3 0.00013 21.3 3.3 2.2 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORX90021.1 - 9e-05 21.9 0.5 0.00012 21.6 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 ORX90021.1 - 0.0039 17.2 0.0 0.017 15.2 0.0 2.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ribosomal_L11_N PF03946.14 ORX90022.1 - 1.5e-24 85.6 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORX90022.1 - 3e-17 62.9 0.2 6.2e-17 61.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain CM_2 PF01817.21 ORX90023.1 - 0.0076 16.6 0.4 0.81 10.1 0.1 2.7 2 1 0 2 2 2 2 Chorismate mutase type II FAT PF02259.23 ORX90024.1 - 2.7e-67 227.5 2.4 2.7e-67 227.5 2.4 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORX90024.1 - 9.2e-31 107.5 0.2 2.3e-30 106.2 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ORX90024.1 - 3.8e-05 23.4 1.0 0.00016 21.4 1.0 2.2 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 ORX90024.1 - 0.059 13.9 1.1 2 9.0 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat TPR_2 PF07719.17 ORX90024.1 - 0.084 13.0 0.0 14 6.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGEF_N_2 PF14663.6 ORX90024.1 - 0.59 10.6 4.6 5.9 7.3 0.0 4.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ApoLp-III PF07464.11 ORX90024.1 - 0.72 9.9 6.1 3 7.9 0.2 4.0 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) SPC12 PF06645.13 ORX90025.1 - 1.8e-29 101.6 0.7 2e-29 101.5 0.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Pkinase PF00069.25 ORX90026.1 - 9.9e-51 172.6 0.0 1.4e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90026.1 - 1.2e-21 77.1 0.0 1.7e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX90026.1 - 0.00032 20.7 0.0 0.00077 19.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX90026.1 - 0.0019 17.2 0.0 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORX90026.1 - 0.038 13.6 0.0 7.1 6.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2339 PF10101.9 ORX90029.1 - 0.62 8.6 14.9 0.074 11.6 6.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2339) MMPL PF03176.15 ORX90029.1 - 1.8 7.4 6.9 0.53 9.2 3.1 1.8 2 0 0 2 2 2 0 MMPL family DUF4271 PF14093.6 ORX90029.1 - 5.1 7.0 44.1 5.6 6.8 4.8 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4271) MHYT PF03707.16 ORX90029.1 - 8.8 6.6 11.9 1.2 9.3 0.1 4.1 4 1 0 4 4 4 0 Bacterial signalling protein N terminal repeat Ribosomal_L31e PF01198.19 ORX90030.1 - 3.3e-39 133.0 2.4 4.1e-39 132.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TPT PF03151.16 ORX90031.1 - 5.9e-29 101.3 22.3 8e-29 100.9 22.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORX90031.1 - 4.6e-08 33.3 35.7 2e-05 24.8 8.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORX90031.1 - 0.004 16.4 23.0 0.01 15.1 23.0 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 ORX90031.1 - 0.0073 15.5 30.1 0.015 14.5 29.5 1.8 1 1 1 2 2 2 1 UAA transporter family UQ_con PF00179.26 ORX90032.1 - 5.8e-45 152.4 0.0 6.7e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX90032.1 - 1.7e-05 25.1 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 ORX90032.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B zf-RING_2 PF13639.6 ORX90034.1 - 2.9e-13 49.9 7.9 6.4e-13 48.8 7.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORX90034.1 - 6.5e-11 41.8 5.2 1.6e-10 40.5 5.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORX90034.1 - 2.3e-07 30.6 8.1 4.7e-07 29.6 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX90034.1 - 6.6e-06 26.3 8.5 2.6e-05 24.4 8.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORX90034.1 - 8.3e-06 25.6 6.1 1.9e-05 24.4 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX90034.1 - 8.3e-05 22.5 4.6 0.00015 21.6 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX90034.1 - 0.00062 19.7 4.7 0.0019 18.2 4.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX90034.1 - 0.0012 18.8 4.1 0.0047 17.0 4.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORX90034.1 - 0.0019 18.0 4.8 0.005 16.7 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRR19-TM PF15176.6 ORX90034.1 - 0.002 18.1 0.1 0.0049 16.8 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Zn_ribbon_17 PF17120.5 ORX90034.1 - 0.031 13.9 8.1 0.077 12.6 6.8 2.4 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORX90034.1 - 0.038 13.8 7.5 0.15 11.9 7.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PA PF02225.22 ORX90034.1 - 0.044 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 PA domain TadE PF07811.12 ORX90034.1 - 0.097 13.0 0.4 0.097 13.0 0.4 1.9 2 0 0 2 2 2 0 TadE-like protein MLANA PF14991.6 ORX90034.1 - 0.099 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A RCR PF12273.8 ORX90034.1 - 0.13 12.9 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Renin_r PF07850.14 ORX90034.1 - 0.17 12.5 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 Renin receptor-like protein FANCL_C PF11793.8 ORX90034.1 - 0.35 11.1 7.3 13 6.1 7.1 3.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 ORX90034.1 - 0.41 11.0 5.5 0.85 10.0 5.5 1.6 1 0 0 1 1 1 0 RING-like domain ATP-synt_8 PF00895.20 ORX90034.1 - 0.94 10.0 5.7 2.8 8.5 0.2 3.0 3 0 0 3 3 2 0 ATP synthase protein 8 EF-hand_1 PF00036.32 ORX90035.1 - 4.3e-14 50.9 0.2 8.8e-05 21.8 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ORX90035.1 - 3.6e-13 48.3 0.4 0.0061 16.4 0.0 4.1 3 2 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 ORX90035.1 - 2.9e-12 46.8 0.1 8.1e-07 29.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 ORX90035.1 - 5.2e-08 33.1 0.0 0.0052 17.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORX90035.1 - 7.2e-08 32.2 2.0 3.1e-05 23.7 0.3 3.8 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 ORX90035.1 - 0.00015 21.1 0.5 0.35 10.5 0.0 3.0 3 0 0 3 3 3 2 EF hand Zip PF02535.22 ORX90037.1 - 5.6e-27 94.8 6.3 7.6e-27 94.4 6.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM-7TMR_HD PF07698.11 ORX90037.1 - 0.0015 18.3 7.6 0.0029 17.4 7.6 1.5 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase DUF1011 PF06237.12 ORX90037.1 - 0.21 12.0 3.2 0.45 10.9 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) Cyt-b5 PF00173.28 ORX90038.1 - 4.7e-23 81.1 0.0 5.9e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4795 PF16043.5 ORX90040.1 - 0.15 11.7 0.5 0.27 10.8 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 ORX90041.1 - 5.7e-19 68.5 0.1 5.1e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX90041.1 - 2.2e-18 66.1 2.0 3.7e-10 39.8 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX90041.1 - 8.8e-16 58.1 0.0 2.9e-06 27.7 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX90041.1 - 1.5e-14 52.6 0.4 0.00065 20.0 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORX90041.1 - 1e-12 47.8 0.4 0.00057 20.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat DUF1843 PF08898.10 ORX90041.1 - 0.19 12.2 0.1 27 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Kin17_mid PF10357.9 ORX90042.1 - 8.7e-51 171.1 2.3 1.6e-50 170.3 2.3 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 ORX90042.1 - 0.0069 16.7 8.9 0.015 15.6 8.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX90042.1 - 0.014 15.7 8.5 0.031 14.6 8.5 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.12 ORX90042.1 - 0.52 10.5 10.8 0.081 13.2 6.1 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Amidohydro_1 PF01979.20 ORX90043.1 - 5.4e-11 42.4 0.0 6.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family DUF4214 PF13946.6 ORX90043.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Glyco_hydro_18 PF00704.28 ORX90045.1 - 2.9e-27 96.2 0.6 1.2e-26 94.2 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Aa_trans PF01490.18 ORX90046.1 - 4.1e-60 203.6 32.0 5.1e-60 203.3 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 ORX90047.1 - 1.2e-55 188.9 29.2 1.5e-55 188.6 29.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FMO-like PF00743.19 ORX90048.1 - 6.2e-14 51.3 0.1 3.3e-13 48.9 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORX90048.1 - 3.2e-12 46.3 0.0 6.8e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORX90048.1 - 2.6e-07 30.2 0.0 8.1e-06 25.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX90048.1 - 9.4e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX90048.1 - 0.019 14.2 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SBDS_C PF09377.10 ORX90048.1 - 0.081 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 SBDS protein C-terminal domain Argos PF11581.8 ORX90049.1 - 0.072 13.1 0.5 0.12 12.4 0.5 1.4 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos PhoLip_ATPase_C PF16212.5 ORX90050.1 - 2.3e-48 165.1 23.9 2.3e-48 165.1 23.9 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX90050.1 - 2.7e-18 65.4 5.9 2.7e-18 65.4 5.9 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 ORX90050.1 - 7.7e-15 54.9 0.2 3.2e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORX90050.1 - 2e-12 47.9 0.0 2.8e-07 31.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX90050.1 - 7.1e-10 38.9 0.0 2.9e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX90050.1 - 0.0012 18.6 0.1 0.0033 17.2 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HTS PF04204.16 ORX90050.1 - 0.099 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine O-succinyltransferase SGTA_dimer PF16546.5 ORX90051.1 - 6.9e-25 86.6 0.1 6.9e-25 86.6 0.1 1.4 2 0 0 2 2 2 1 Homodimerisation domain of SGTA Ndc1_Nup PF09531.10 ORX90052.1 - 2.1e-96 324.0 16.9 2.4e-96 323.8 16.9 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Mito_carr PF00153.27 ORX90053.1 - 1.8e-71 236.1 3.3 3.3e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 ORX90053.1 - 0.32 11.1 3.4 1.1 9.4 0.2 3.0 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif UCH PF00443.29 ORX90054.1 - 9.8e-51 172.7 0.0 1.6e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX90054.1 - 5.5e-09 36.0 0.0 4.5e-07 29.8 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DnaJ_C PF01556.18 ORX90055.1 - 1.1e-42 145.6 1.2 1.5e-42 145.2 1.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORX90055.1 - 6.1e-28 96.7 2.3 9.8e-28 96.1 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORX90055.1 - 2.1e-16 60.0 21.6 3.9e-16 59.2 21.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORX90055.1 - 7e-05 22.7 9.3 0.0073 16.2 1.1 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORX90055.1 - 0.027 14.5 9.5 0.44 10.6 2.8 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RPT PF13446.6 ORX90055.1 - 0.18 11.7 0.0 0.45 10.5 0.0 1.6 1 1 0 1 1 1 0 A repeated domain in UCH-protein Bac_rhamnosid PF05592.11 ORX90056.1 - 0.047 13.7 0.1 18 5.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Phosphodiest PF01663.22 ORX90057.1 - 0.0049 16.5 0.3 0.0055 16.3 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2462 PF09495.10 ORX90058.1 - 0.03 15.0 2.5 0.051 14.3 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) Tet_JBP PF12851.7 ORX90059.1 - 0.00071 19.0 0.5 0.82 9.0 2.2 2.4 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily DUF1126 PF06565.12 ORX90059.1 - 0.025 14.4 1.2 5.2 6.9 0.1 2.2 2 0 0 2 2 2 0 DUF1126 PH-like domain DUF2462 PF09495.10 ORX90059.1 - 0.45 11.3 15.9 0.19 12.5 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) BUD22 PF09073.10 ORX90059.1 - 0.63 9.3 15.9 0.15 11.4 2.5 2.1 2 0 0 2 2 2 0 BUD22 SR-25 PF10500.9 ORX90059.1 - 1 8.9 17.6 1.4 8.5 6.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NARP1 PF12569.8 ORX90060.1 - 0.017 14.0 7.3 0.022 13.7 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SR-25 PF10500.9 ORX90060.1 - 0.046 13.3 13.0 0.074 12.7 13.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 ORX90060.1 - 0.4 10.7 8.6 0.55 10.3 8.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Dicty_REP PF05086.12 ORX90060.1 - 0.81 7.6 5.6 1 7.2 5.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 ORX90060.1 - 0.88 9.6 5.4 1.2 9.2 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TetR_C_19 PF17924.1 ORX90060.1 - 0.99 10.0 5.3 2.5 8.7 5.3 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SelP_N PF04592.14 ORX90060.1 - 2.6 7.4 18.1 3.6 6.9 18.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 ORX90060.1 - 3.4 6.3 3.7 4.4 6.0 3.7 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 ORX90060.1 - 6.2 5.9 9.4 7.3 5.7 9.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1126 PF06565.12 ORX90061.1 - 0.18 11.6 1.2 12 5.8 0.1 2.3 2 0 0 2 2 2 0 DUF1126 PH-like domain FAM60A PF15396.6 ORX90061.1 - 0.22 11.5 12.2 2.7 7.9 0.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 ORX90061.1 - 0.36 10.5 25.0 1.9 8.2 7.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 ORX90061.1 - 0.53 9.6 22.6 0.33 10.3 4.1 2.1 2 0 0 2 2 2 0 BUD22 SR-25 PF10500.9 ORX90061.1 - 0.9 9.1 24.3 2.9 7.5 11.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tet_JBP PF12851.7 ORX90061.1 - 1.2 8.4 11.3 1.7e+02 1.3 11.3 2.4 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily NARP1 PF12569.8 ORX90061.1 - 1.4 7.7 15.3 0.22 10.4 5.6 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Dicty_REP PF05086.12 ORX90061.1 - 1.9 6.3 8.9 2.9 5.8 5.1 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Peptidase_S49_N PF08496.10 ORX90061.1 - 2.1 8.4 16.7 1.9 8.5 6.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Presenilin PF01080.17 ORX90061.1 - 4.4 6.0 5.0 32 3.1 0.0 2.1 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 ORX90061.1 - 4.6 7.2 10.0 11 5.9 4.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TetR_C_19 PF17924.1 ORX90061.1 - 6 7.5 11.0 1.9 9.1 3.7 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2462 PF09495.10 ORX90062.1 - 0.00023 21.8 13.7 0.078 13.7 2.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2462) CK1gamma_C PF12605.8 ORX90062.1 - 0.0035 18.5 0.5 0.42 11.8 0.0 2.3 2 0 0 2 2 2 1 Casein kinase 1 gamma C terminal DUF1126 PF06565.12 ORX90062.1 - 0.017 14.9 1.0 6.1 6.7 0.1 2.2 2 0 0 2 2 2 0 DUF1126 PH-like domain ParD_like PF11903.8 ORX90062.1 - 0.03 14.4 0.3 12 6.1 0.0 2.4 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system FAM75 PF14650.6 ORX90062.1 - 0.043 13.4 1.8 3.4 7.1 0.2 2.1 2 0 0 2 2 2 0 FAM75 family Cwf_Cwc_15 PF04889.12 ORX90062.1 - 0.045 13.5 18.7 0.53 10.0 4.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PcfK PF14058.6 ORX90062.1 - 0.92 9.8 6.6 11 6.3 0.5 2.3 2 0 0 2 2 2 0 PcfK-like protein SR-25 PF10500.9 ORX90062.1 - 1.2 8.8 13.3 3.2 7.3 1.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2462 PF09495.10 ORX90063.1 - 0.03 15.1 3.5 0.046 14.4 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) Pox_Ag35 PF03286.14 ORX90063.1 - 0.36 10.6 4.1 0.56 10.0 4.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Phosphodiest PF01663.22 ORX90064.1 - 0.013 15.1 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2462 PF09495.10 ORX90064.1 - 0.026 15.2 3.2 0.043 14.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) Tristanin_u2 PF16638.5 ORX90069.1 - 0.029 15.2 3.4 0.029 15.2 3.4 2.7 1 1 2 3 3 3 0 Unstructured region on methyltransferase between zinc-fingers Cwf_Cwc_15 PF04889.12 ORX90069.1 - 1.5 8.5 6.6 3 7.5 0.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ras PF00071.22 ORX90071.1 - 1.9e-65 219.4 1.2 2.2e-65 219.2 1.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90071.1 - 1.1e-36 125.7 0.7 1.5e-36 125.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90071.1 - 1.4e-17 63.7 0.2 1.8e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX90071.1 - 6.6e-06 25.8 0.5 1.7e-05 24.5 0.3 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORX90071.1 - 1e-05 25.1 0.1 1.2e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX90071.1 - 1.1e-05 25.4 0.7 0.13 12.2 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 ORX90071.1 - 1.9e-05 24.2 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORX90071.1 - 3.2e-05 24.0 0.0 5.8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORX90071.1 - 0.0033 17.3 0.2 0.0091 15.8 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORX90071.1 - 0.0039 16.7 0.3 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 ORX90071.1 - 0.0059 17.0 0.0 0.32 11.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX90071.1 - 0.0088 16.4 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORX90071.1 - 0.018 15.0 0.1 0.036 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ORX90071.1 - 0.04 14.4 0.1 0.081 13.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ORX90071.1 - 0.043 14.1 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORX90071.1 - 0.046 13.5 0.1 1.1 9.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 ORX90071.1 - 0.047 13.0 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Septin DUF3873 PF12989.7 ORX90071.1 - 0.048 14.0 0.1 0.095 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_29 PF13555.6 ORX90071.1 - 0.054 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORX90071.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein rve PF00665.26 ORX90071.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain WD40 PF00400.32 ORX90072.1 - 3.5e-33 113.1 23.4 1.1e-05 26.1 0.6 7.2 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90072.1 - 1e-15 57.8 5.8 8.1e-06 26.1 0.0 5.1 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX90072.1 - 5.4e-09 36.2 1.0 6.1e-05 23.0 0.1 3.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX90072.1 - 3.1e-08 33.3 0.8 4.8e-06 26.1 0.0 2.9 2 1 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 ORX90072.1 - 0.00067 18.7 0.6 0.6 9.0 0.2 3.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORX90072.1 - 0.0022 16.6 0.1 0.27 9.7 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 ORX90072.1 - 0.0025 17.7 0.1 21 5.2 0.0 4.4 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat SGL PF08450.12 ORX90072.1 - 0.0049 16.5 0.2 1.5 8.3 0.0 3.0 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region CLTH PF10607.9 ORX90072.1 - 0.018 14.9 0.4 0.026 14.4 0.4 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Nup160 PF11715.8 ORX90072.1 - 0.02 13.6 0.2 0.16 10.6 0.1 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 ORX90072.1 - 0.029 13.4 4.0 3.6 6.5 0.1 3.2 3 1 0 3 3 3 0 Coatomer WD associated region SdiA-regulated PF06977.11 ORX90072.1 - 0.086 12.0 0.0 0.55 9.4 0.0 2.2 2 1 0 2 2 2 0 SdiA-regulated Gmad1 PF10647.9 ORX90072.1 - 0.15 11.8 0.0 0.94 9.2 0.0 2.3 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain ATP-sulfurylase PF01747.17 ORX90073.1 - 3.6e-89 297.8 0.1 5.1e-89 297.3 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 ORX90073.1 - 7.7e-54 181.9 0.0 1.1e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 ORX90073.1 - 1.4e-53 180.8 0.0 2.4e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 ORX90073.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SH3_1 PF00018.28 ORX90074.1 - 3.9e-16 58.4 0.0 3.2e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORX90074.1 - 1.9e-15 56.4 0.0 4.2e-08 32.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORX90074.1 - 6.7e-12 44.9 0.0 2.1e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 ORX90074.1 - 2.3e-06 27.5 0.0 5.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PX PF00787.24 ORX90074.1 - 1.1e-05 25.3 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PX domain PUF PF00806.19 ORX90074.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat SH3_3 PF08239.11 ORX90074.1 - 0.15 12.4 0.1 6.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain ATP-sulfurylase PF01747.17 ORX90075.1 - 3.6e-89 297.8 0.1 5.1e-89 297.3 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 ORX90075.1 - 1.4e-53 180.8 0.0 2.4e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 ORX90075.1 - 4e-53 179.5 0.0 5.9e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORX90075.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MRC1 PF09444.10 ORX90076.1 - 1.2e-22 81.0 19.1 1.2e-22 81.0 19.1 3.4 4 0 0 4 4 4 2 MRC1-like domain Pox_A_type_inc PF04508.12 ORX90076.1 - 0.046 13.6 0.7 0.12 12.2 0.7 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat BCDHK_Adom3 PF10436.9 ORX90081.1 - 6.8e-08 32.5 0.8 1e-07 32.0 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX90081.1 - 1.2e-07 32.3 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PP2C PF00481.21 ORX90082.1 - 3.5e-82 275.9 0.0 4.5e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Zn_clus PF00172.18 ORX90083.1 - 0.31 11.2 15.5 0.28 11.3 12.7 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1a PF11670.8 ORX90086.1 - 0.019 14.3 3.9 1.4 8.1 0.1 2.0 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) UPF0669 PF17065.5 ORX90086.1 - 0.14 11.9 0.5 14 5.3 0.1 2.0 1 1 1 2 2 2 0 Putative cytokine, C6ORF120 Rbx_binding PF18113.1 ORX90086.1 - 0.18 11.6 0.2 23 4.9 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain A_amylase_inhib PF01356.19 ORX90086.1 - 3.6 7.6 10.9 5.2 7.1 0.8 2.6 3 0 0 3 3 3 0 Alpha amylase inhibitor DSPc PF00782.20 ORX90090.1 - 1.7e-32 112.0 0.1 3.4e-32 111.0 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX90090.1 - 6e-05 22.7 0.0 9.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORX90090.1 - 0.021 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 ORX90091.1 - 2.3e-151 503.7 1.2 2.8e-151 503.4 1.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 ORX90091.1 - 0.00086 19.1 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX90091.1 - 0.0084 15.7 0.2 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORX90091.1 - 0.0094 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family HTH_29 PF13551.6 ORX90091.1 - 0.1 12.6 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix PPR_2 PF13041.6 ORX90092.1 - 1.3e-129 422.2 12.6 5.1e-17 61.8 0.0 16.2 3 2 14 17 17 17 15 PPR repeat family PPR PF01535.20 ORX90092.1 - 6.2e-83 267.4 13.3 4.9e-06 26.4 0.0 16.9 17 0 0 17 17 17 14 PPR repeat PPR_1 PF12854.7 ORX90092.1 - 8.8e-83 271.7 0.0 5.4e-09 35.6 0.0 16.1 17 0 0 17 17 17 13 PPR repeat PPR_3 PF13812.6 ORX90092.1 - 4.2e-79 260.6 5.9 5e-13 48.9 0.0 11.1 7 3 4 11 11 11 10 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX90092.1 - 4e-45 153.8 2.7 3.9e-12 46.0 0.0 6.4 2 1 5 7 7 7 6 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORX90092.1 - 1.7e-11 43.6 3.7 0.00085 18.3 0.8 5.4 2 2 2 5 5 5 2 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 ORX90092.1 - 4.8e-11 43.1 7.4 2.7 8.4 0.0 9.3 2 2 6 9 9 9 3 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ORX90092.1 - 9.5e-06 25.5 3.4 0.057 13.3 0.0 6.1 2 2 3 7 7 7 1 Mitochondrial ATPase expression Vps39_1 PF10366.9 ORX90092.1 - 0.0088 16.3 1.7 41 4.5 0.0 5.4 3 3 3 6 6 6 0 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 ORX90092.1 - 0.0095 15.8 0.7 1.4 8.7 0.0 4.0 2 1 0 3 3 3 1 Region in Clathrin and VPS ADK PF00406.22 ORX90092.1 - 0.05 13.7 0.4 25 4.9 0.0 3.6 2 1 1 3 3 3 0 Adenylate kinase AAA_17 PF13207.6 ORX90092.1 - 0.056 13.9 0.1 40 4.6 0.0 3.7 2 1 2 4 4 4 0 AAA domain Marek_A PF02124.15 ORX90092.1 - 0.17 11.7 0.7 8.8 6.1 0.0 2.8 3 1 0 3 3 3 0 Marek's disease glycoprotein A FAD_binding_4 PF01565.23 ORX90094.1 - 6.7e-34 116.6 2.2 4e-33 114.1 2.9 1.9 2 0 0 2 2 2 1 FAD binding domain Cytokin-bind PF09265.10 ORX90094.1 - 2e-05 24.2 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding BBE PF08031.12 ORX90094.1 - 4.8e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like CSS-motif PF12792.7 ORX90094.1 - 0.073 12.5 0.2 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 CSS motif domain associated with EAL Acetyltransf_3 PF13302.7 ORX90095.1 - 7.7e-24 84.9 0.0 1.1e-23 84.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX90095.1 - 0.00011 22.4 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.24 ORX90096.1 - 1.7e-96 323.8 27.7 2e-96 323.6 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90096.1 - 6.1e-23 81.3 48.9 1.8e-18 66.6 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2970 PF11174.8 ORX90097.1 - 0.12 12.2 2.9 0.18 11.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) CAF1-p150_N PF15557.6 ORX90098.1 - 0.095 12.6 1.0 0.24 11.3 0.3 1.7 1 1 1 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA ADH_N PF08240.12 ORX90099.1 - 1.7e-27 95.4 3.2 2.8e-27 94.8 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX90099.1 - 3.8e-20 72.2 0.0 6.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX90099.1 - 0.00024 22.1 0.0 0.00044 21.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX90099.1 - 0.0032 16.8 0.2 0.0052 16.1 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX90099.1 - 0.052 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Corona_I PF03187.14 ORX90099.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein CoA_binding PF02629.19 ORX90099.1 - 0.16 12.7 0.2 0.46 11.2 0.1 1.8 1 1 1 2 2 2 0 CoA binding domain TrkA_N PF02254.18 ORX90099.1 - 0.17 12.1 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 ORX90100.1 - 3.3e-06 26.7 0.0 6.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX90100.1 - 0.00071 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 KR domain COG5 PF10392.9 ORX90101.1 - 0.045 13.9 0.3 0.14 12.3 0.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V-ATPase_G PF03179.15 ORX90101.1 - 0.65 10.6 3.6 0.43 11.1 0.5 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF3759 PF12585.8 ORX90103.1 - 2.1e-35 120.6 8.3 2.5e-35 120.3 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Mito_carr PF00153.27 ORX90104.1 - 1.5e-65 217.2 1.5 4.4e-21 74.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Trehalase PF01204.18 ORX90105.1 - 1.9e-176 587.9 0.0 2.3e-176 587.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 ORX90105.1 - 1.4e-13 50.3 1.2 1.4e-13 50.3 1.2 2.0 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain S1 PF00575.23 ORX90106.1 - 5.1e-79 260.6 45.9 4.1e-16 59.1 1.8 14.7 15 1 0 15 15 15 11 S1 RNA binding domain Suf PF05843.14 ORX90106.1 - 1.4e-07 31.8 0.6 1.4e-07 31.8 0.6 4.6 2 1 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 ORX90106.1 - 4.2e-06 27.2 0.2 0.68 10.5 0.1 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX90106.1 - 0.00021 21.4 0.0 0.07 13.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat PCB_OB PF17092.5 ORX90106.1 - 0.00046 20.9 4.5 3.8 8.3 0.1 6.6 5 1 0 6 6 5 1 Penicillin-binding protein OB-like domain S1_2 PF13509.6 ORX90106.1 - 0.0026 17.8 1.0 0.89 9.7 0.1 4.9 5 0 0 5 5 5 1 S1 domain TPR_8 PF13181.6 ORX90106.1 - 0.003 17.6 0.4 1.4 9.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX90106.1 - 0.004 17.9 0.0 4.9 8.2 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 ORX90106.1 - 0.017 15.0 1.2 3.1 7.8 0.1 4.1 4 0 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain TPR_16 PF13432.6 ORX90106.1 - 0.018 15.7 0.0 0.098 13.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX90106.1 - 0.028 14.7 0.4 0.59 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX90106.1 - 0.13 13.0 0.5 95 4.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX90106.1 - 0.17 12.0 0.1 21 5.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX90106.1 - 0.2 11.8 0.3 0.8 10.0 0.0 2.2 3 0 0 3 3 1 0 Tetratricopeptide repeat FAD_binding_1 PF00667.20 ORX90107.1 - 2.6e-50 171.0 0.0 3.9e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX90107.1 - 9.4e-33 113.4 0.0 3.2e-32 111.7 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORX90107.1 - 3e-17 63.2 0.0 7.8e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 ORX90107.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_3 PF12641.7 ORX90107.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain IFRD PF05004.13 ORX90108.1 - 2e-64 217.6 9.1 2e-64 217.6 9.1 1.5 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DUF374 PF04028.13 ORX90108.1 - 0.00056 19.4 0.0 0.003 17.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF374) HEAT PF02985.22 ORX90108.1 - 0.0071 16.5 1.0 1.7 9.1 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat RTP1_C1 PF10363.9 ORX90108.1 - 0.082 13.1 0.4 2.7 8.2 0.4 3.0 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 IFRD_C PF04836.12 ORX90108.1 - 2.1 9.0 11.9 0.13 12.8 2.1 3.6 3 1 0 3 3 3 0 Interferon-related protein conserved region PP-binding PF00550.25 ORX90109.1 - 8.7e-13 48.4 0.1 1.2e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORX90109.1 - 3.7e-06 27.1 0.3 4.9e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 ORX90109.1 - 0.083 13.4 0.4 0.11 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Exo_endo_phos PF03372.23 ORX90110.1 - 1.1e-22 80.7 0.1 4.4e-22 78.7 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 ORX90110.1 - 3.5e-11 43.2 6.5 3.9e-07 30.3 1.4 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX90110.1 - 5.2e-10 38.9 14.4 2.7e-06 27.1 2.6 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 ORX90110.1 - 0.013 16.0 8.4 0.81 10.5 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 ORX90110.1 - 0.036 14.1 6.0 0.34 11.1 0.3 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Sec23_trunk PF04811.15 ORX90111.1 - 5.2e-74 248.9 0.0 7.2e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORX90111.1 - 1.3e-29 102.7 0.0 2.8e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORX90111.1 - 2e-25 88.6 0.1 4.1e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORX90111.1 - 2.4e-16 59.5 6.6 5e-16 58.4 6.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORX90111.1 - 4.1e-13 49.0 0.0 1.4e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORX90111.1 - 0.099 12.0 0.3 0.27 10.7 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CLTH PF10607.9 ORX90112.1 - 2.3e-39 134.6 0.1 3.4e-39 134.1 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORX90112.1 - 3.4e-09 36.3 0.8 8.8e-09 35.0 0.2 2.0 2 0 0 2 2 2 1 LisH Ion_trans PF00520.31 ORX90113.1 - 5.2e-17 61.9 14.5 3.3e-12 46.2 2.6 2.1 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 ORX90113.1 - 1.8e-11 43.8 5.5 1.8e-11 43.8 5.5 2.4 2 2 0 2 2 2 1 Ion channel Lig_chan PF00060.26 ORX90113.1 - 0.16 11.8 4.3 0.16 11.8 0.2 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel BIR PF00653.21 ORX90114.1 - 1.7e-43 147.1 9.5 3.2e-22 79.0 3.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 ORX90114.1 - 0.2 11.7 1.8 9.9 6.3 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger DAHP_synth_1 PF00793.20 ORX90115.1 - 9.5e-102 339.5 0.0 1.2e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family FCH PF00611.23 ORX90115.1 - 0.062 13.6 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1330 PF07045.11 ORX90115.1 - 0.17 12.2 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) LPMO_10 PF03067.15 ORX90116.1 - 0.0053 17.4 1.3 0.0053 17.4 1.3 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Orthopox_B11R PF07033.11 ORX90116.1 - 0.08 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus B11R protein CBM9_1 PF06452.11 ORX90117.1 - 1.4e-06 28.4 2.0 1.4e-06 28.4 0.5 1.8 2 1 0 2 2 2 1 Carbohydrate family 9 binding domain-like Aldose_epim PF01263.20 ORX90119.1 - 1.7e-23 83.4 0.3 5.8e-13 48.8 0.1 2.7 1 1 1 2 2 2 2 Aldose 1-epimerase BRO1 PF03097.18 ORX90120.1 - 1.3e-135 452.2 2.3 1.3e-135 452.2 2.3 1.4 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORX90120.1 - 1.9e-26 93.0 2.7 1.9e-26 93.0 2.7 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF2443 PF10398.9 ORX90120.1 - 0.081 13.0 0.5 1 9.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) SlyX PF04102.12 ORX90120.1 - 0.09 13.4 0.6 0.58 10.8 0.1 2.7 3 0 0 3 3 3 0 SlyX Spc29 PF17082.5 ORX90120.1 - 0.093 12.6 2.6 0.27 11.0 2.0 2.0 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF3951 PF13131.6 ORX90120.1 - 0.21 11.8 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Arrestin_C PF02752.22 ORX90121.1 - 1e-17 64.8 0.6 6.5e-09 36.3 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90121.1 - 3.3e-08 33.7 0.2 1.7e-07 31.4 0.2 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX90121.1 - 0.0035 16.6 0.1 0.0066 15.7 0.1 1.4 1 0 0 1 1 1 1 Rgp1 Spo0M PF07070.11 ORX90121.1 - 0.042 13.4 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein FAINT PF04385.15 ORX90121.1 - 0.13 12.4 1.6 0.31 11.1 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function, DUF529 Ribosomal_L36e PF01158.18 ORX90122.1 - 3.5e-42 142.6 7.3 3.9e-42 142.4 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mago-bind PF09282.10 ORX90122.1 - 0.23 11.4 1.7 7.4 6.5 0.2 2.6 2 0 0 2 2 2 0 Mago binding UBA PF00627.31 ORX90123.1 - 2.5e-28 97.5 2.5 8.1e-14 51.2 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 ORX90123.1 - 1e-21 76.4 1.5 1.7e-21 75.7 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 ORX90123.1 - 1.3e-21 76.0 16.3 1.3e-21 76.0 16.3 2.0 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.8 ORX90123.1 - 1.7e-09 37.4 2.5 3.7e-09 36.3 2.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 ORX90123.1 - 0.00032 20.4 0.1 0.62 9.9 0.0 2.9 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain WIYLD PF10440.9 ORX90123.1 - 0.00036 20.3 0.2 0.094 12.5 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain Ubiquitin_2 PF14560.6 ORX90123.1 - 0.0021 18.5 0.2 0.0021 18.5 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORX90123.1 - 0.0065 16.4 0.4 0.016 15.2 0.4 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HEPN_Toprim_N PF18871.1 ORX90123.1 - 0.014 15.4 1.7 0.04 13.8 0.2 2.1 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 Ubiquitin_5 PF18037.1 ORX90123.1 - 0.1 13.0 1.4 0.19 12.1 1.4 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Creatinase_N_2 PF16189.5 ORX90124.1 - 4.9e-53 179.5 0.0 2e-52 177.6 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORX90124.1 - 5.7e-47 160.1 0.0 8.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ORX90124.1 - 1.1e-21 76.6 0.2 4.2e-21 74.8 0.2 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ORX90124.1 - 7.9e-20 71.9 0.0 2.1e-16 60.8 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain RTT107_BRCT_5 PF16770.5 ORX90125.1 - 1.5e-20 72.9 2.9 1e-19 70.3 0.4 3.0 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 ORX90125.1 - 3.4e-19 69.0 4.6 8.4e-07 29.3 0.0 3.9 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORX90125.1 - 1.1e-16 60.5 2.4 4.2e-12 45.8 0.8 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT_2 PF16589.5 ORX90125.1 - 1.5e-09 38.2 0.1 0.00088 19.6 0.0 3.7 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 ORX90125.1 - 0.00041 20.4 1.2 0.63 10.2 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Sec16 PF12932.7 ORX90125.1 - 0.013 16.1 0.9 0.42 11.2 0.0 2.5 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region PEPCK_GTP PF00821.18 ORX90126.1 - 7.1e-163 541.6 0.0 8.8e-163 541.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 ORX90126.1 - 4.8e-101 336.9 0.0 6.3e-101 336.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PapG_N PF03627.13 ORX90127.1 - 0.024 14.3 0.4 0.039 13.6 0.4 1.3 1 0 0 1 1 1 0 PapG carbohydrate binding domain FMO-like PF00743.19 ORX90129.1 - 8.4e-38 130.1 0.0 2.4e-22 79.1 0.0 4.2 3 2 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORX90129.1 - 1.3e-18 67.3 0.6 8.2e-15 54.8 0.1 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX90129.1 - 3.6e-13 49.4 0.0 1.5e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX90129.1 - 1.4e-06 27.7 0.0 2.9e-05 23.4 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORX90129.1 - 1.5e-05 25.1 0.0 3.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORX90129.1 - 1.7e-05 24.2 0.0 6.3e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ORX90129.1 - 2.3e-05 24.2 0.5 0.021 14.4 0.1 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORX90129.1 - 6.1e-05 23.1 0.1 0.1 12.6 0.2 3.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ORX90129.1 - 0.00025 19.9 0.1 0.0024 16.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORX90129.1 - 0.00099 19.6 0.1 0.055 14.0 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORX90129.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.12 ORX90129.1 - 0.0072 15.9 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 ORX90129.1 - 0.0091 16.1 0.0 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORX90129.1 - 0.017 15.0 0.0 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ORX90129.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ORX90129.1 - 0.031 13.6 0.0 4.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORX90129.1 - 0.036 13.4 0.3 0.07 12.4 0.0 1.5 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORX90129.1 - 0.038 14.4 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 ORX90129.1 - 0.044 13.8 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 ORX90129.1 - 0.11 11.6 0.2 0.34 9.9 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 ORX90129.1 - 0.21 11.7 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TauD PF02668.16 ORX90130.1 - 1.7e-31 110.0 0.0 2.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ORX90130.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 CsiD AA_permease_2 PF13520.6 ORX90131.1 - 1.2e-55 189.1 41.1 2.2e-43 148.7 27.6 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 ORX90131.1 - 1.6e-22 79.8 34.0 1.1e-18 67.2 22.3 2.2 1 1 1 2 2 2 2 Amino acid permease Tetraspanin PF00335.20 ORX90131.1 - 0.027 14.2 5.9 0.24 11.1 0.3 2.8 2 0 0 2 2 2 0 Tetraspanin family tRNA-synt_1e PF01406.19 ORX90132.1 - 6.7e-130 432.8 1.3 1.2e-129 432.0 1.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ORX90132.1 - 4e-09 35.7 1.8 5.2e-06 25.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORX90132.1 - 9.5e-05 20.8 0.0 0.0003 19.2 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 ORX90132.1 - 0.0041 17.6 1.5 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.21 ORX90132.1 - 0.0054 15.7 2.9 0.0058 15.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 ORX90132.1 - 0.016 14.2 0.1 0.16 10.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) UvrA_inter PF17760.1 ORX90132.1 - 0.15 12.2 1.1 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 UvrA interaction domain FUSC_2 PF13515.6 ORX90133.1 - 4.1e-15 56.0 7.3 4.1e-15 56.0 7.3 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORX90133.1 - 3.3e-13 49.1 5.2 8.2e-11 41.2 0.0 2.7 2 1 1 3 3 3 3 Fusaric acid resistance protein family ArAE_2 PF10334.9 ORX90133.1 - 1.1e-12 48.3 0.9 1.8e-10 41.1 0.4 2.5 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORX90133.1 - 1.7e-11 43.9 0.2 3.1e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ORX90133.1 - 2.7e-11 43.0 6.1 1.4e-10 40.6 3.3 2.8 3 0 0 3 3 3 1 Aluminium activated malate transporter OppC_N PF12911.7 ORX90133.1 - 0.091 12.8 0.9 9.7 6.3 0.2 2.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C LysM PF01476.20 ORX90134.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 LysM domain HLH PF00010.26 ORX90135.1 - 1.2e-14 54.0 3.0 1.2e-14 54.0 3.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FH2 PF02181.23 ORX90135.1 - 0.0059 15.8 2.7 0.0067 15.6 2.7 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain KASH_CCD PF14662.6 ORX90135.1 - 0.01 15.7 6.4 0.012 15.4 6.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Takusan PF04822.13 ORX90135.1 - 0.015 15.2 2.7 0.067 13.1 0.7 2.1 1 1 1 2 2 2 0 Takusan TINF2_N PF14973.6 ORX90135.1 - 0.021 15.2 1.5 0.025 14.9 1.5 1.1 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF3685 PF12452.8 ORX90135.1 - 0.026 14.2 0.9 0.029 14.1 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) MobL PF18555.1 ORX90135.1 - 0.08 12.2 4.6 0.084 12.1 4.6 1.0 1 0 0 1 1 1 0 MobL relaxases FAA_hydro_N_2 PF18288.1 ORX90135.1 - 0.11 12.9 0.3 0.17 12.3 0.2 1.4 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 HrpA_pilin PF09589.10 ORX90135.1 - 0.2 12.4 3.3 0.31 11.8 0.3 2.0 2 0 0 2 2 2 0 HrpA pilus formation protein UPF0242 PF06785.11 ORX90135.1 - 0.3 11.2 7.3 0.32 11.1 7.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMEM247 PF15444.6 ORX90135.1 - 0.62 10.1 4.8 0.81 9.7 4.8 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 YabA PF06156.13 ORX90135.1 - 0.65 10.7 6.3 0.53 11.0 3.2 1.9 1 1 0 2 2 2 0 Initiation control protein YabA DUF5345 PF17280.2 ORX90135.1 - 3.6 7.6 6.0 10 6.2 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) HSP70 PF00012.20 ORX90136.1 - 6e-122 407.8 2.9 6.9e-122 407.6 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX90136.1 - 1.6e-11 43.6 0.0 2.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 ORX90136.1 - 0.00045 19.4 0.0 0.032 13.3 0.0 2.4 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; MAPKK1_Int PF08923.10 ORX90136.1 - 0.0079 16.0 0.1 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 Mitogen-activated protein kinase kinase 1 interacting DUF2274 PF10038.9 ORX90136.1 - 0.038 14.4 1.4 0.35 11.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) DUF4646 PF15496.6 ORX90137.1 - 1.5e-30 106.4 0.0 1.7e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 ORX90137.1 - 0.021 14.9 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family YjcQ PF09639.10 ORX90137.1 - 0.2 11.9 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 YjcQ protein Sugar_tr PF00083.24 ORX90138.1 - 9.6e-102 341.1 27.0 1.3e-101 340.7 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90138.1 - 4.4e-28 98.2 25.0 4.4e-28 98.2 25.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4229 PF14012.6 ORX90138.1 - 4.5 7.4 8.8 0.35 11.0 1.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) Catalase PF00199.19 ORX90139.1 - 7.7e-176 584.8 0.1 6.8e-175 581.7 0.0 1.9 2 0 0 2 2 2 1 Catalase Catalase_C PF18011.1 ORX90139.1 - 5e-32 110.6 0.0 8.2e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORX90139.1 - 2e-20 72.7 0.1 5.9e-20 71.3 0.1 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 ORX90139.1 - 1.9e-07 31.0 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4646 PF15496.6 ORX90140.1 - 4.5e-30 104.8 0.0 5.1e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 ORX90140.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family F-box-like PF12937.7 ORX90141.1 - 5.3e-12 45.4 1.8 1e-11 44.5 1.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX90141.1 - 8.1e-09 35.1 0.8 1.9e-08 34.0 0.2 2.0 1 1 1 2 2 2 1 F-box domain F-box_4 PF15966.5 ORX90141.1 - 0.019 14.8 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 F-box FERM_C PF09380.10 ORX90141.1 - 0.086 13.2 1.2 0.25 11.7 1.2 1.8 1 1 0 1 1 1 0 FERM C-terminal PH-like domain Sugar_tr PF00083.24 ORX90142.1 - 1.8e-101 340.3 27.6 2.4e-101 339.8 27.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90142.1 - 1e-27 97.0 26.2 1e-27 97.0 26.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4229 PF14012.6 ORX90142.1 - 4.5 7.4 8.8 0.35 11.0 1.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) Catalase PF00199.19 ORX90143.1 - 3.4e-152 507.0 0.5 4.3e-128 427.7 0.1 2.4 2 1 1 3 3 3 2 Catalase Catalase_C PF18011.1 ORX90143.1 - 8.5e-31 106.6 0.0 1.5e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ORX90143.1 - 3.3e-21 75.2 0.1 7.8e-21 74.1 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 ORX90143.1 - 4.3e-08 33.1 0.0 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1829 PF08862.10 ORX90143.1 - 0.069 13.6 0.1 19 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF1829 Ras PF00071.22 ORX90144.1 - 2.2e-63 212.7 0.2 2.6e-63 212.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90144.1 - 4.9e-36 123.6 0.1 7.4e-36 123.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90144.1 - 8e-14 51.5 0.1 9.5e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX90144.1 - 9.2e-08 32.2 0.1 1.6e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX90144.1 - 6.2e-05 23.0 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORX90144.1 - 0.0003 20.4 0.1 0.001 18.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORX90144.1 - 0.00039 19.9 0.0 0.00067 19.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 ORX90144.1 - 0.0024 18.1 0.1 0.024 14.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX90144.1 - 0.0047 17.3 0.1 0.0075 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORX90144.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ORX90144.1 - 0.023 15.2 0.2 0.03 14.8 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 ORX90144.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 ORX90144.1 - 0.056 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MgpC PF05220.12 ORX90144.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 MgpC protein precursor AAA_24 PF13479.6 ORX90144.1 - 0.066 12.9 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORX90144.1 - 0.069 13.2 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ORX90144.1 - 0.074 12.3 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain FeoB_N PF02421.18 ORX90144.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 ORX90144.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 ORX90144.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 ORX90144.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 ORX90146.1 - 9.6e-15 54.7 2.5 4.4e-06 27.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90146.1 - 2.9e-11 43.5 0.0 0.0045 17.3 0.0 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Adaptin_N PF01602.20 ORX90147.1 - 4.5e-146 487.5 2.5 5.5e-146 487.2 2.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORX90147.1 - 5.7e-25 87.8 0.5 1.1e-24 86.9 0.5 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORX90147.1 - 7.8e-11 42.3 10.6 2.1e-09 37.6 0.6 4.0 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX90147.1 - 1.5e-07 31.7 1.8 0.4 11.1 0.0 5.2 4 1 0 4 4 4 2 HEAT repeats API5 PF05918.11 ORX90147.1 - 9.9e-05 21.3 0.4 0.0034 16.3 0.3 2.3 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) DNA_alkylation PF08713.11 ORX90147.1 - 0.019 14.7 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 DNA alkylation repair enzyme HEAT PF02985.22 ORX90147.1 - 0.07 13.4 5.3 13 6.4 0.1 5.6 5 1 1 6 6 6 0 HEAT repeat ParcG PF10274.9 ORX90147.1 - 0.2 11.8 1.0 0.45 10.6 0.1 2.1 2 1 0 2 2 2 0 Parkin co-regulated protein Ras PF00071.22 ORX90148.1 - 5e-56 188.8 0.1 5.8e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90148.1 - 9.1e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90148.1 - 1.8e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX90148.1 - 1.1e-05 25.0 0.2 0.00016 21.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX90148.1 - 0.00043 20.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX90148.1 - 0.0078 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX90148.1 - 0.01 15.4 0.2 0.13 11.8 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 ORX90148.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 ORX90148.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORX90148.1 - 0.085 12.9 0.3 0.16 12.0 0.3 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORX90148.1 - 0.16 12.4 0.1 0.29 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Methyltransf_23 PF13489.6 ORX90149.1 - 0.00041 20.2 0.0 0.00069 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX90149.1 - 0.00096 19.9 0.0 0.75 10.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORX90150.1 - 1.5e-05 24.9 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX90150.1 - 2.8e-05 24.8 0.0 0.036 14.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 ORX90150.1 - 0.089 12.6 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORX90150.1 - 0.2 12.4 0.1 2 9.1 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain PAD_porph PF04371.15 ORX90151.1 - 1.6e-99 333.2 0.0 1.9e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Gpr1_Fun34_YaaH PF01184.19 ORX90151.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Apolipoprotein PF01442.18 ORX90152.1 - 8.4e-19 68.2 177.2 1.6e-06 28.1 56.8 6.4 1 1 5 6 6 6 6 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 ORX90152.1 - 0.00016 21.7 255.3 0.0024 17.9 13.2 16.0 2 2 14 17 17 17 12 Late embryogenesis abundant protein YtxH PF12732.7 ORX90152.1 - 0.051 14.1 195.8 0.59 10.7 10.6 14.4 2 1 9 11 11 11 0 YtxH-like protein DUF883 PF05957.13 ORX90152.1 - 0.1 13.2 159.9 0.2 12.3 12.2 11.6 3 1 9 12 12 12 0 Bacterial protein of unknown function (DUF883) MTHFR PF02219.17 ORX90153.1 - 1.5e-120 401.9 0.0 1.9e-120 401.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3665 PF12427.8 ORX90153.1 - 0.082 12.6 0.6 0.17 11.6 0.6 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Ribosomal_60s PF00428.19 ORX90154.1 - 2.8e-26 91.9 12.1 3.2e-26 91.7 12.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein L51_S25_CI-B8 PF05047.16 ORX90155.1 - 1.9e-06 27.7 0.6 2.9e-05 23.9 0.3 2.4 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_S19 PF00203.21 ORX90156.1 - 1.1e-36 124.5 1.1 1.6e-36 124.0 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SH3_9 PF14604.6 ORX90157.1 - 4e-12 45.8 0.0 8.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX90157.1 - 1.2e-09 37.6 0.1 3.1e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 ORX90157.1 - 5.1e-06 26.1 0.0 0.59 9.6 0.0 3.8 2 1 1 3 3 3 2 Cortical protein marker for cell polarity SH3_2 PF07653.17 ORX90157.1 - 4.1e-05 23.2 0.0 9.6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 ORX90157.1 - 0.0022 18.2 0.9 55 4.2 0.1 5.3 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 ORX90157.1 - 0.076 13.0 0.3 38 4.4 0.1 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF5122 PF17164.4 ORX90157.1 - 0.95 9.8 13.1 0.18 12.1 0.2 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Milton PF12448.8 ORX90157.1 - 1.1 9.3 3.5 18 5.4 0.1 2.7 2 0 0 2 2 2 0 Kinesin associated protein Kelch_2 PF07646.15 ORX90157.1 - 2.1 8.5 7.2 1.5e+02 2.6 0.0 5.7 6 0 0 6 6 6 0 Kelch motif WD40 PF00400.32 ORX90158.1 - 8.3e-23 80.3 20.2 0.00068 20.4 1.3 11.6 13 1 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90158.1 - 8.8e-17 61.2 3.1 0.0012 19.1 0.0 7.0 6 2 1 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 ORX90158.1 - 0.0004 20.3 3.1 0.033 14.1 0.2 2.9 2 1 1 3 3 3 2 Region in Clathrin and VPS Nup160 PF11715.8 ORX90158.1 - 0.017 13.8 0.7 0.086 11.5 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 MIT PF04212.18 ORX90158.1 - 0.074 13.1 0.6 17 5.5 0.2 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 ORX90158.1 - 0.4 10.7 5.8 29 4.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF2A PF08662.11 ORX90158.1 - 0.48 10.3 2.6 87 2.9 0.1 4.1 5 1 0 5 5 5 0 Eukaryotic translation initiation factor eIF2A TPR_12 PF13424.6 ORX90158.1 - 2.3 8.6 6.3 4 7.8 3.6 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX90158.1 - 5.5 7.4 8.7 22 5.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ARL2_Bind_BART PF11527.8 ORX90159.1 - 0.0049 17.0 0.5 0.55 10.3 0.0 2.6 1 1 1 2 2 2 2 The ARF-like 2 binding protein BART HSM3_N PF18795.1 ORX90159.1 - 0.048 13.1 2.2 0.18 11.2 0.5 2.3 1 1 1 2 2 2 0 DNA mismatch repair protein HSM3, N terminal domain Bac_globin PF01152.21 ORX90160.1 - 5e-07 29.9 0.0 6.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial-like globin Glycos_transf_2 PF00535.26 ORX90160.1 - 0.09 12.6 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 FMN_red PF03358.15 ORX90161.1 - 0.002 17.9 0.1 0.0028 17.4 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase ArfGap PF01412.18 ORX90162.1 - 3.5e-39 133.5 0.2 4.1e-39 133.3 0.2 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NDC10_II PF16787.5 ORX90162.1 - 0.025 13.7 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 FMN_red PF03358.15 ORX90163.1 - 1.2e-10 41.4 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX90163.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold COX5A PF02284.16 ORX90164.1 - 3.4e-39 133.0 0.0 4.3e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF2357 PF09823.9 ORX90164.1 - 0.039 13.2 0.1 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) tRNA-synt_1 PF00133.22 ORX90165.1 - 1.6e-171 571.6 0.0 2.2e-171 571.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORX90165.1 - 7.3e-27 94.2 0.1 2.8e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORX90165.1 - 4.6e-21 75.0 0.1 4e-15 55.5 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORX90165.1 - 5.5e-05 22.8 0.0 9.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ORX90165.1 - 0.00019 20.9 0.9 0.23 10.7 0.0 3.3 3 1 1 4 4 4 2 tRNA synthetases class I (C) catalytic domain ANT PF03374.14 ORX90165.1 - 0.002 18.4 0.2 3.3 8.1 0.0 2.6 2 0 0 2 2 2 2 Phage antirepressor protein KilAC domain UBA PF00627.31 ORX90166.1 - 1.6e-30 104.5 5.6 6.3e-15 54.7 0.8 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 ORX90166.1 - 1.9e-24 85.1 19.4 3.4e-24 84.3 19.4 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 ORX90166.1 - 6.5e-22 77.1 2.0 1.1e-21 76.3 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX90166.1 - 4.5e-10 39.2 2.9 7.5e-10 38.5 2.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 ORX90166.1 - 0.00028 20.6 0.1 0.7 9.8 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 ORX90166.1 - 0.00088 19.4 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORX90166.1 - 0.0016 18.8 1.7 0.0023 18.4 0.4 1.9 3 0 0 3 3 1 1 Ubiquitin-like domain WIYLD PF10440.9 ORX90166.1 - 0.0041 16.9 0.1 0.073 12.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain Ubiquitin_5 PF18037.1 ORX90166.1 - 0.0092 16.3 0.7 0.018 15.4 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 ORX90166.1 - 0.025 15.1 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 ORX90166.1 - 0.03 14.0 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 CUE domain TBK1_ULD PF18396.1 ORX90166.1 - 0.035 14.0 2.0 0.067 13.1 0.2 2.2 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain FlgN PF05130.12 ORX90166.1 - 0.036 14.6 1.6 0.036 14.6 1.6 2.0 2 0 0 2 2 2 0 FlgN protein SOG2 PF10428.9 ORX90166.1 - 0.13 11.4 8.7 0.19 10.9 8.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ubiquitin_4 PF18036.1 ORX90166.1 - 0.37 10.9 1.1 1.3 9.1 0.5 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain Rib_recp_KP_reg PF05104.12 ORX90166.1 - 0.87 10.6 19.4 0.049 14.7 10.6 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Nif11 PF07862.11 ORX90166.1 - 1.9 8.8 4.7 75 3.7 4.7 2.8 1 1 0 1 1 1 0 Nif11 domain DUF4112 PF13430.6 ORX90167.1 - 1e-28 99.7 0.1 1.1e-28 99.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HEAT PF02985.22 ORX90168.1 - 1.3e-14 53.0 0.1 0.11 12.8 0.0 5.6 5 0 0 5 5 5 4 HEAT repeat Pkinase PF00069.25 ORX90168.1 - 1.8e-09 37.4 0.0 3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 ORX90168.1 - 1.7e-08 34.7 0.0 0.00018 21.6 0.0 2.3 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 ORX90168.1 - 4.8e-08 32.6 0.0 7.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 ORX90168.1 - 3.1e-05 24.3 0.0 0.16 12.4 0.0 2.8 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 ORX90168.1 - 0.00062 20.2 0.0 4 8.1 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 ORX90168.1 - 0.0092 14.6 0.3 0.014 13.9 0.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region NUSAP PF16006.5 ORX90168.1 - 0.024 14.4 1.0 0.024 14.4 1.0 2.0 2 0 0 2 2 2 0 Nucleolar and spindle-associated protein Kinase-like PF14531.6 ORX90168.1 - 0.048 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Vac14_Fab1_bd PF12755.7 ORX90168.1 - 0.066 13.8 0.0 14 6.3 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region SPX PF03105.19 ORX90168.1 - 0.64 9.9 12.4 0.16 11.9 8.7 1.7 2 0 0 2 2 2 0 SPX domain Npa1 PF11707.8 ORX90170.1 - 3.5e-96 322.5 2.9 4.4e-96 322.2 0.1 2.5 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 ORX90170.1 - 3.6e-60 203.0 3.5 2.9e-59 200.1 0.1 4.4 4 1 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Xrn1_D3 PF18194.1 ORX90170.1 - 0.017 15.2 0.1 0.07 13.2 0.1 2.1 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 DUF3336 PF11815.8 ORX90170.1 - 0.4 10.4 3.2 1 9.1 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) Arrestin_C PF02752.22 ORX90172.1 - 8.3e-11 42.5 0.0 1.3e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90172.1 - 5.8e-10 39.4 0.0 8.7e-09 35.6 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX90172.1 - 0.0075 15.5 0.0 0.054 12.7 0.0 1.9 2 0 0 2 2 2 1 Rgp1 LDB19 PF13002.7 ORX90172.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like DUF3337 PF11816.8 ORX90173.1 - 2.2e-51 174.1 0.0 3.8e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 ORX90173.1 - 3.7e-19 68.7 12.3 3e-06 27.9 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 ORX90173.1 - 1.7e-05 23.8 0.7 0.75 8.5 0.1 3.3 3 0 0 3 3 3 3 Nup133 N terminal like ANAPC4_WD40 PF12894.7 ORX90173.1 - 4.2e-05 23.8 0.1 0.0047 17.2 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX90173.1 - 0.042 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Nup160 PF11715.8 ORX90173.1 - 0.38 9.3 3.9 0.48 9.0 0.1 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TH1 PF04858.13 ORX90174.1 - 1.5e-102 344.1 0.0 1.8e-102 343.9 0.0 1.0 1 0 0 1 1 1 1 TH1 protein eRF1_1 PF03463.15 ORX90175.1 - 4.8e-54 181.8 0.2 8e-54 181.1 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 ORX90175.1 - 2e-32 112.3 0.3 2.9e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORX90175.1 - 7.3e-26 90.9 0.0 2.2e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 DUF1664 PF07889.12 ORX90176.1 - 0.0001 22.4 10.9 0.016 15.3 2.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) ADIP PF11559.8 ORX90176.1 - 0.0015 18.6 16.1 0.016 15.3 2.1 2.5 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Herpes_UL6 PF01763.16 ORX90176.1 - 0.0022 16.6 2.9 0.0022 16.6 2.9 2.1 1 1 1 2 2 2 1 Herpesvirus UL6 like NPV_P10 PF05531.12 ORX90176.1 - 0.022 15.2 2.0 0.22 12.0 0.1 2.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cas6 PF09559.10 ORX90176.1 - 0.068 13.1 3.2 0.12 12.3 3.2 1.3 1 0 0 1 1 1 0 Cas6 Crispr Atg14 PF10186.9 ORX90176.1 - 0.098 11.7 10.2 0.29 10.2 10.2 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 ORX90176.1 - 0.23 10.3 14.5 0.04 12.8 1.4 2.1 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Mod_r PF07200.13 ORX90176.1 - 0.32 11.1 18.0 0.088 12.9 1.8 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.11 ORX90176.1 - 0.45 10.3 7.2 0.6 9.9 1.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 ApoC-I PF04691.12 ORX90176.1 - 0.96 9.4 2.9 14 5.7 0.0 3.0 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) LMBR1 PF04791.16 ORX90176.1 - 1.6 7.5 7.0 6 5.7 6.9 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein HemX PF04375.14 ORX90176.1 - 1.7 7.8 12.3 2.1 7.6 3.5 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMPIT PF07851.13 ORX90176.1 - 2.1 7.5 8.8 0.22 10.7 1.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 ORX90176.1 - 4.8 7.7 11.8 19 5.8 2.6 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 FUSC PF04632.12 ORX90176.1 - 4.9 5.6 6.4 2.7 6.4 0.5 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Rx_N PF18052.1 ORX90176.1 - 5.5 7.3 7.1 1.3 9.3 1.4 2.5 2 0 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 ORX90176.1 - 5.6 7.4 10.9 5.2 7.5 0.5 3.6 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 ORX90176.1 - 6 6.1 13.8 5 6.3 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 ORX90176.1 - 6.9 6.2 16.3 0.62 9.6 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Spc24 PF08286.11 ORX90176.1 - 7.3 6.9 14.1 8 6.8 1.5 2.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 CLZ PF16526.5 ORX90176.1 - 7.7 6.9 14.7 4.7 7.7 0.9 3.1 3 1 1 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_Mu_Gam PF07352.12 ORX90176.1 - 8.6 6.3 9.3 0.93 9.4 2.6 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DHR10 PF18595.1 ORX90176.1 - 9.2 6.4 22.3 0.17 12.0 5.0 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 ORX90176.1 - 9.6 6.5 5.8 6 7.2 0.8 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORX90176.1 - 9.6 6.4 11.8 14 5.8 3.5 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 ORX90176.1 - 9.8 5.5 20.0 0.72 9.2 1.8 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PS_Dcarbxylase PF02666.15 ORX90177.1 - 4.1e-60 202.7 0.0 6.1e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ORX90177.1 - 8.1e-37 125.6 0.0 1.2e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF1033 PF06279.11 ORX90177.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) DUF4179 PF13786.6 ORX90178.1 - 0.17 12.4 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) GRP PF07172.11 ORX90180.1 - 4.7 8.0 24.7 3.6 8.3 22.6 1.7 1 1 1 2 2 2 0 Glycine rich protein family GRP PF07172.11 ORX90181.1 - 9.4 7.0 23.8 13 6.5 23.8 1.4 1 1 0 1 1 1 0 Glycine rich protein family FXR_C1 PF16096.5 ORX90184.1 - 5.1 7.4 9.4 3.1 8.1 4.0 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Pox_RNA_Pol_19 PF05320.12 ORX90188.1 - 3.3 7.6 5.2 2.3 8.2 3.6 1.5 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit LYRIC PF15686.5 ORX90191.1 - 0.066 12.8 0.8 0.078 12.5 0.8 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Acetyltransf_9 PF13527.7 ORX90196.1 - 1.8e-10 41.0 0.0 3.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX90196.1 - 2.9e-05 24.4 0.0 6.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX90196.1 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family SBDS PF01172.18 ORX90197.1 - 4.9e-21 74.6 0.3 6e-21 74.3 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SLAC1 PF03595.17 ORX90198.1 - 1.7e-72 244.4 41.2 2.2e-72 244.0 41.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3343 PF11823.8 ORX90198.1 - 0.079 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RRM_1 PF00076.22 ORX90200.1 - 4.5e-16 58.4 0.0 6.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med6 PF04934.14 ORX90201.1 - 2.8e-46 156.6 0.1 4.8e-46 155.9 0.1 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component GATA PF00320.27 ORX90202.1 - 4.9e-30 102.9 18.8 2.6e-15 55.7 4.9 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX90202.1 - 2.7e-07 30.0 5.0 0.00062 19.2 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX90202.1 - 0.0005 20.1 1.4 1 9.5 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORX90202.1 - 0.0021 18.2 6.7 0.19 11.9 0.5 2.8 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2318 PF10080.9 ORX90202.1 - 0.22 11.7 4.9 5.4 7.2 1.7 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-RRN7 PF11781.8 ORX90202.1 - 0.51 10.1 7.9 1.3 8.8 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 ORX90202.1 - 1.6 8.7 5.7 3.7 7.5 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Sulfate_transp PF00916.20 ORX90203.1 - 5.5e-92 308.4 17.8 3.4e-91 305.8 17.8 1.9 1 1 0 1 1 1 1 Sulfate permease family NAD_binding_6 PF08030.12 ORX90204.1 - 6.7e-35 120.5 0.0 1.1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORX90204.1 - 1.6e-22 79.6 0.2 4.3e-22 78.3 0.1 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 ORX90204.1 - 1.2e-19 70.7 11.8 1.2e-19 70.7 11.8 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ORX90204.1 - 0.0029 18.2 0.0 0.013 16.2 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORX90204.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Voldacs PF03517.13 ORX90205.1 - 7.8e-11 42.3 0.6 1.9e-10 41.0 0.6 1.6 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling GRAM PF02893.20 ORX90205.1 - 0.002 18.0 0.1 0.0028 17.5 0.1 1.3 1 0 0 1 1 1 1 GRAM domain RBD-FIP PF09457.10 ORX90205.1 - 0.14 12.1 2.3 3.3 7.7 0.1 2.5 2 1 0 2 2 2 0 FIP domain Ist1 PF03398.14 ORX90207.1 - 5.3e-60 202.1 1.9 6.7e-60 201.7 1.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Steroid_dh PF02544.16 ORX90208.1 - 1.4e-18 67.3 2.7 1.4e-18 67.3 2.7 2.1 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORX90208.1 - 0.0014 19.0 1.2 0.13 12.7 0.1 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF1295 PF06966.12 ORX90208.1 - 0.0082 15.7 1.3 0.015 14.9 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Papo_T_antigen PF02380.15 ORX90208.1 - 0.022 14.9 0.9 0.022 14.9 0.9 2.0 2 0 0 2 2 2 0 T-antigen specific domain WW PF00397.26 ORX90209.1 - 5.2e-07 29.6 1.7 1.3e-06 28.3 1.7 1.8 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 ORX90209.1 - 0.035 14.4 1.3 0.076 13.3 1.3 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain zf-C3HC4_3 PF13920.6 ORX90210.1 - 8.1e-06 25.6 8.0 9.1e-06 25.4 8.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Peptidase_C74 PF12387.8 ORX90210.1 - 0.51 9.8 2.4 0.55 9.7 2.4 1.1 1 0 0 1 1 1 0 Pestivirus NS2 peptidase NTP_transferase PF00483.23 ORX90211.1 - 1e-12 48.2 0.0 5.7e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORX90211.1 - 0.00096 19.5 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain SPK PF04435.18 ORX90211.1 - 0.026 14.9 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF545) Mito_carr PF00153.27 ORX90212.1 - 1.7e-66 220.2 0.6 8.4e-26 89.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5518 PF17647.1 ORX90212.1 - 0.38 10.9 5.7 5.8 7.1 0.0 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5518) Methyltransf_25 PF13649.6 ORX90214.1 - 5.7e-13 49.4 0.3 3e-12 47.1 0.0 2.4 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX90214.1 - 1.8e-11 44.5 0.4 1.5e-10 41.5 0.0 2.7 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX90214.1 - 5.8e-10 39.2 0.2 4e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORX90214.1 - 9.3e-10 38.4 0.8 1.2e-09 38.0 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORX90214.1 - 1.1e-06 28.6 0.0 1.3e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORX90214.1 - 9.7e-06 25.6 0.1 1.9e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX90214.1 - 1.1e-05 25.0 0.6 2.2e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase small domain zf-C2H2_2 PF12756.7 ORX90214.1 - 1.2e-05 25.5 0.6 3.7e-05 24.0 0.6 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_12 PF08242.12 ORX90214.1 - 0.00014 22.5 0.1 0.0018 19.0 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORX90214.1 - 0.00043 19.3 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 ORX90214.1 - 0.0006 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 ORX90214.1 - 0.001 18.5 0.1 0.0025 17.2 0.1 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 ORX90214.1 - 0.0081 15.5 0.2 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORX90214.1 - 0.03 13.6 0.1 0.062 12.6 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 ORX90214.1 - 0.038 13.8 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 ORX90214.1 - 0.067 13.2 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 ORX90214.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C2H2_3rep PF18868.1 ORX90214.1 - 0.12 13.1 0.1 0.26 12.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Cons_hypoth95 PF03602.15 ORX90214.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-Di19 PF05605.12 ORX90214.1 - 0.39 11.0 2.0 0.7 10.2 2.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 ORX90216.1 - 1.1e-13 50.7 9.9 2.5e-07 30.8 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90216.1 - 1.8e-09 37.6 9.2 0.00017 22.1 1.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX90216.1 - 1.9e-06 28.1 19.4 5.1e-06 26.7 4.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain FOXP-CC PF16159.5 ORX90216.1 - 7.6e-05 23.3 1.7 0.013 16.1 0.1 2.0 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORX90216.1 - 0.00061 20.0 3.3 0.06 13.5 0.9 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORX90216.1 - 0.0043 17.3 4.8 0.063 13.6 0.8 2.9 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX90216.1 - 0.0057 16.9 0.9 0.0085 16.4 0.8 1.4 1 1 0 1 1 1 1 C2H2-type zinc ribbon CHORD PF04968.12 ORX90216.1 - 0.0094 16.7 2.8 1.6 9.5 0.2 2.1 1 1 1 2 2 2 2 CHORD zf-TRAF PF02176.18 ORX90216.1 - 0.021 15.5 3.5 0.89 10.3 0.5 2.1 1 1 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.7 ORX90216.1 - 0.058 13.8 4.9 1.6 9.3 0.0 2.5 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX90216.1 - 0.06 13.3 0.3 12 5.9 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 ORX90216.1 - 0.078 12.8 0.4 0.078 12.8 0.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORX90216.1 - 0.17 11.9 6.5 0.36 10.9 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 ORX90216.1 - 0.31 11.1 5.7 0.28 11.2 0.6 2.2 2 0 0 2 2 2 0 BED zinc finger PI3_PI4_kinase PF00454.27 ORX90217.1 - 2.3e-57 194.7 0.3 4.8e-57 193.6 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ORX90217.1 - 4.3e-11 42.4 0.6 1e-10 41.3 0.1 2.0 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 ORX90217.1 - 2e-08 33.9 7.5 3.3e-08 33.1 7.5 1.4 1 0 0 1 1 1 1 FAT domain DUF4423 PF14394.6 ORX90217.1 - 0.64 9.7 5.0 2.9 7.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) Zn_clus PF00172.18 ORX90218.1 - 0.00013 22.0 12.3 0.00013 22.0 12.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORX90218.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold Ribosomal_L2_C PF03947.18 ORX90221.1 - 3.7e-49 166.1 3.1 5.8e-49 165.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORX90221.1 - 5.1e-16 58.4 0.0 1.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Epimerase PF01370.21 ORX90222.1 - 1.7e-21 76.8 0.0 2.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX90222.1 - 3.8e-21 75.3 0.0 4.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX90222.1 - 1.1e-15 57.5 0.3 2.4e-13 49.9 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORX90222.1 - 1.4e-12 47.7 0.0 7.7e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORX90222.1 - 6.1e-11 42.5 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX90222.1 - 4.1e-09 36.3 0.0 8.6e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORX90222.1 - 7.3e-06 25.3 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORX90222.1 - 9.1e-06 25.7 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORX90222.1 - 0.00083 18.9 0.1 0.0099 15.3 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ORX90222.1 - 0.063 12.4 0.0 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain MarR_2 PF12802.7 ORX90222.1 - 0.1 12.5 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 MarR family RSN1_7TM PF02714.15 ORX90223.1 - 2.4e-76 256.7 32.0 4.7e-76 255.7 32.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORX90223.1 - 2.2e-37 128.2 3.2 2.2e-37 128.2 3.2 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORX90223.1 - 1.7e-30 106.5 0.0 2.6e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORX90223.1 - 0.032 14.4 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter ox_reductase_C PF08635.10 ORX90224.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Arrestin_N PF00339.29 ORX90226.1 - 2.3e-07 31.0 0.6 6.4e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX90226.1 - 2.3e-07 31.3 0.0 0.00025 21.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PhnJ PF06007.11 ORX90226.1 - 0.0083 15.2 1.4 0.014 14.5 1.4 1.2 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnJ NmrA PF05368.13 ORX90228.1 - 4.5e-07 29.7 0.0 5.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX90228.1 - 7.5e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF3533 PF12051.8 ORX90229.1 - 2.9e-29 102.2 10.5 3.6e-29 101.8 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 ORX90229.1 - 3.4e-17 62.6 11.7 4.2e-17 62.3 11.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 ORX90229.1 - 1.2e-05 24.8 16.8 1.2e-05 24.8 16.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter FAD_binding_7 PF03441.14 ORX90230.1 - 1.5e-60 204.1 2.3 1.5e-60 204.1 2.3 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORX90230.1 - 2.4e-30 105.7 0.0 4.9e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase GSIII_N PF12437.8 ORX90231.1 - 2.6e-61 206.0 0.1 2.6e-61 206.0 0.1 1.7 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORX90231.1 - 6e-36 122.9 0.5 1.4e-35 121.7 0.5 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORX90231.1 - 5.3e-21 75.0 0.1 1.8e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Cytochrom_B562 PF07361.11 ORX90231.1 - 0.095 13.4 0.1 0.31 11.7 0.1 1.9 1 0 0 1 1 1 0 Cytochrome b562 DUF2277 PF10041.9 ORX90231.1 - 0.16 12.3 0.3 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) GSIII_N PF12437.8 ORX90232.1 - 1.2e-66 223.3 0.2 2e-66 222.6 0.2 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORX90232.1 - 6.9e-36 122.7 0.3 1.7e-35 121.4 0.3 1.7 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORX90232.1 - 1.2e-20 73.8 0.0 2.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain zf-U1 PF06220.12 ORX90232.1 - 0.029 14.1 0.4 0.076 12.8 0.4 1.7 1 0 0 1 1 1 0 U1 zinc finger DUF4495 PF14906.6 ORX90232.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) DUF1664 PF07889.12 ORX90232.1 - 2.5 8.1 4.8 30 4.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L13e PF01294.18 ORX90233.1 - 7.7e-82 273.5 7.5 1.1e-81 273.1 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L32e PF01655.18 ORX90234.1 - 5.7e-54 181.1 2.9 7.8e-54 180.7 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 DCP1 PF06058.13 ORX90235.1 - 2.6e-41 140.2 0.2 3.3e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Iron_permease PF04120.12 ORX90236.1 - 7.4e-35 119.5 13.1 5.9e-15 55.2 0.3 4.4 5 0 0 5 5 5 4 Low affinity iron permease RGS PF00615.19 ORX90237.1 - 1.2e-09 38.4 0.6 2.1e-09 37.7 0.6 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain LptF_LptG PF03739.14 ORX90237.1 - 0.0018 17.2 0.2 0.0018 17.2 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG DUF4909 PF16253.5 ORX90237.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) Glyco_hydro_20 PF00728.22 ORX90239.1 - 3.3e-95 319.5 1.0 4.4e-95 319.1 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORX90239.1 - 1.2e-23 84.3 0.0 2.3e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORX90239.1 - 1.1e-06 29.4 0.0 6.3e-06 27.0 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 MIP PF00230.20 ORX90240.1 - 3.6e-30 105.4 9.7 4.4e-30 105.1 9.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ipi1_N PF12333.8 ORX90242.1 - 6e-20 71.7 3.2 1e-19 71.0 0.2 3.0 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.7 ORX90242.1 - 8e-09 35.7 1.2 1.2e-05 25.4 0.1 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX90242.1 - 0.018 15.4 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats DUF4539 PF15072.6 ORX90243.1 - 6.6e-29 99.8 0.3 1e-28 99.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) FtsJ PF01728.19 ORX90244.1 - 1.2e-69 234.0 0.0 1.4e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF5446 PF17522.2 ORX90244.1 - 0.042 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5446) KH_1 PF00013.29 ORX90245.1 - 1e-19 70.1 5.3 2.6e-08 33.6 0.0 4.7 6 0 0 6 6 6 3 KH domain MOEP19 PF16005.5 ORX90245.1 - 0.036 14.1 0.2 30 4.7 0.0 3.9 3 1 1 4 4 4 0 KH-like RNA-binding domain HAD_2 PF13419.6 ORX90246.1 - 1.4e-07 31.8 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX90246.1 - 0.0049 16.9 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Peptidase_M28 PF04389.17 ORX90247.1 - 1.9e-41 142.0 0.0 4.7e-41 140.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 IPPT PF01715.17 ORX90248.1 - 3e-71 239.9 0.7 3e-69 233.3 0.3 2.1 2 0 0 2 2 2 2 IPP transferase AAA_18 PF13238.6 ORX90248.1 - 0.0002 21.9 1.8 0.25 11.9 0.1 2.9 1 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX90248.1 - 0.00028 21.1 0.2 0.11 12.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain IPT PF01745.16 ORX90248.1 - 0.024 14.0 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase PDEase_I PF00233.19 ORX90248.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Ploopntkinase3 PF18751.1 ORX90248.1 - 0.1 12.5 0.1 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 GDP_Man_Dehyd PF16363.5 ORX90249.1 - 6e-58 196.8 0.0 2.8e-57 194.6 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX90249.1 - 2.3e-47 161.5 0.0 3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX90249.1 - 8.9e-09 34.7 0.0 1.3e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORX90249.1 - 1.2e-08 34.5 0.1 3.3e-06 26.5 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORX90249.1 - 4.2e-08 32.7 0.0 0.00027 20.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 ORX90249.1 - 2.3e-07 30.2 0.0 3.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORX90249.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Myosin_head PF00063.21 ORX90250.1 - 3e-255 848.6 5.7 5.9e-255 847.7 3.7 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 ORX90250.1 - 2.2e-20 72.9 1.7 2.2e-20 72.9 1.7 2.3 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 ORX90250.1 - 1.9e-09 36.5 24.9 0.017 14.9 0.5 6.1 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 ORX90250.1 - 0.00032 20.5 0.3 0.001 18.8 0.3 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 ORX90250.1 - 0.0084 16.4 0.1 0.058 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TetR_C_36 PF18598.1 ORX90250.1 - 0.027 14.4 0.3 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ABC_tran PF00005.27 ORX90250.1 - 0.16 12.5 0.6 1.5 9.4 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 ORX90250.1 - 0.25 11.7 0.0 0.25 11.7 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain HSF_DNA-bind PF00447.17 ORX90250.1 - 0.81 10.3 3.3 0.81 10.3 0.5 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding ERM PF00769.19 ORX90250.1 - 8.1 6.2 13.9 0.46 10.3 7.5 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nic96 PF04097.14 ORX90251.1 - 1e-193 645.2 3.0 1.3e-193 644.9 3.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TBPIP PF07106.13 ORX90252.1 - 1.8e-13 50.2 0.2 1.8e-13 50.2 0.2 2.5 3 1 0 3 3 3 1 TBPIP/Hop2 winged helix domain PilJ PF13675.6 ORX90252.1 - 7.2e-05 22.8 0.4 0.00023 21.1 0.1 1.8 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term LZ3wCH PF18517.1 ORX90252.1 - 0.00041 20.4 2.2 0.0005 20.1 0.1 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Thymidylat_synt PF00303.19 ORX90252.1 - 0.0022 17.2 0.2 0.005 16.0 0.1 1.6 2 0 0 2 2 2 1 Thymidylate synthase PhageMin_Tail PF10145.9 ORX90252.1 - 0.015 15.1 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein Phasin PF05597.11 ORX90252.1 - 0.018 15.0 0.4 0.078 13.0 0.1 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Med28 PF11594.8 ORX90252.1 - 0.022 14.9 0.4 1.6 8.8 0.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 28 Penicillinase_R PF03965.16 ORX90252.1 - 0.036 14.4 0.3 1.4 9.2 0.1 2.9 2 1 1 3 3 3 0 Penicillinase repressor Atg14 PF10186.9 ORX90252.1 - 0.052 12.6 4.5 0.093 11.8 4.6 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GvpG PF05120.12 ORX90252.1 - 0.074 13.1 2.3 0.17 11.9 2.3 1.7 1 0 0 1 1 1 0 Gas vesicle protein G Fmp27_WPPW PF10359.9 ORX90252.1 - 0.076 11.9 2.4 0.089 11.6 2.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1843 PF08898.10 ORX90252.1 - 0.11 13.0 1.2 0.19 12.3 0.3 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) DUF2267 PF10025.9 ORX90252.1 - 0.11 12.8 0.0 0.39 11.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF2458 PF10454.9 ORX90252.1 - 0.12 12.0 3.8 0.73 9.5 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) DivIC PF04977.15 ORX90252.1 - 0.14 11.9 10.5 0.54 10.1 3.4 2.5 1 1 1 2 2 2 0 Septum formation initiator SpoIISA_toxin PF14171.6 ORX90252.1 - 0.15 11.7 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system SseC PF04888.12 ORX90252.1 - 0.15 11.6 1.4 0.22 11.1 0.3 1.8 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family bZIP_1 PF00170.21 ORX90252.1 - 0.17 12.0 10.9 1.3 9.2 1.2 2.6 1 1 1 2 2 2 0 bZIP transcription factor FapA PF03961.13 ORX90252.1 - 0.23 10.0 4.3 0.26 9.9 4.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 ORX90252.1 - 0.33 11.2 7.4 0.19 12.0 1.9 2.2 2 0 0 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 ORX90252.1 - 0.38 11.3 9.5 1.7 9.2 9.5 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Med9 PF07544.13 ORX90252.1 - 0.39 10.8 7.7 4 7.6 7.7 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CENP-H PF05837.12 ORX90252.1 - 0.68 10.4 6.6 5.5 7.4 0.7 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Nnf1 PF03980.14 ORX90252.1 - 0.76 10.2 8.1 6.8 7.1 8.1 2.2 1 1 0 1 1 1 0 Nnf1 Jnk-SapK_ap_N PF09744.9 ORX90252.1 - 0.95 9.7 9.5 1.3 9.2 8.5 1.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 MetOD2 PF18548.1 ORX90252.1 - 1.1 9.4 7.4 2 8.5 1.2 2.7 1 1 2 3 3 3 0 Metanogen output domain 2 YabA PF06156.13 ORX90252.1 - 2.1 9.0 8.1 11 6.8 1.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 ORX90252.1 - 9.9 6.7 13.4 12 6.4 10.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapB ATG16 PF08614.11 ORX90253.1 - 1.9e-40 139.2 30.9 2.5e-40 138.8 30.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 ORX90253.1 - 5.3e-40 134.7 23.3 9.8e-07 29.4 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90253.1 - 2e-19 69.7 4.1 0.00032 20.9 0.0 6.6 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX90253.1 - 1.8e-09 37.8 0.0 0.004 17.1 0.0 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX90253.1 - 3.9e-06 26.4 1.1 0.0067 15.8 0.2 3.2 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 ORX90253.1 - 2.7e-05 22.9 0.2 0.00017 20.3 0.1 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF5046 PF16465.5 ORX90253.1 - 0.00012 21.6 0.1 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 ORX90253.1 - 0.00091 18.3 7.3 0.54 9.2 0.0 4.4 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF16 PF01519.16 ORX90253.1 - 0.0082 16.6 12.4 0.0082 16.6 12.4 2.9 1 1 2 3 3 3 1 Protein of unknown function DUF16 PQQ_3 PF13570.6 ORX90253.1 - 0.032 14.7 2.1 0.23 12.0 0.1 3.4 5 0 0 5 5 4 0 PQQ-like domain FUSC PF04632.12 ORX90253.1 - 2.9 6.3 4.0 3.9 5.9 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 ORX90253.1 - 4.5 7.8 8.9 1.6 9.3 4.4 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 ORX90253.1 - 5.7 7.3 8.4 2.6 8.4 4.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) EF-hand_13 PF17958.1 ORX90254.1 - 4.3e-25 87.3 0.0 2.4e-24 84.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ORX90254.1 - 3.7e-16 59.3 3.3 2.1e-14 53.7 0.3 3.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 ORX90254.1 - 0.0031 16.9 0.3 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 ORX90254.1 - 0.011 15.2 3.4 0.088 12.4 0.1 3.6 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 ORX90254.1 - 0.047 13.6 4.6 0.53 10.2 0.0 4.4 5 0 0 5 5 5 0 EF-hand domain pair EF-hand_6 PF13405.6 ORX90254.1 - 0.07 13.1 0.0 0.07 13.1 0.0 3.8 5 0 0 5 5 5 0 EF-hand domain zf-H2C2_2 PF13465.6 ORX90255.1 - 3.9e-14 52.3 7.5 9.9e-08 32.1 0.7 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX90255.1 - 6.1e-12 45.3 22.0 5.5e-05 23.4 4.7 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90255.1 - 6.4e-11 42.1 18.3 0.00026 21.5 3.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX90255.1 - 7.8e-07 28.9 8.7 0.00084 19.3 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 ORX90255.1 - 8.4e-05 22.9 8.1 0.046 14.2 0.1 2.4 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORX90255.1 - 0.00094 19.4 6.6 1.5 9.2 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX90255.1 - 0.0047 17.2 6.5 0.029 14.7 6.5 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon C1_1 PF00130.22 ORX90255.1 - 0.0052 16.6 0.6 0.0052 16.6 0.6 1.7 2 1 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 ORX90255.1 - 0.0057 16.7 4.4 0.39 10.9 0.0 2.7 2 1 1 3 3 3 2 Zinc ribbon domain zf-met PF12874.7 ORX90255.1 - 0.0079 16.6 10.5 1.4 9.5 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF2757 PF10955.8 ORX90255.1 - 0.0084 16.3 1.7 2.4 8.5 0.1 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2757) zf-C2H2_11 PF16622.5 ORX90255.1 - 0.02 14.6 11.2 0.95 9.3 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type HypA PF01155.19 ORX90255.1 - 0.043 13.8 1.3 0.05 13.6 1.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 ORX90255.1 - 0.045 13.9 14.9 1.2 9.4 7.9 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger zf_ZIC PF18366.1 ORX90255.1 - 0.052 13.7 5.7 10 6.3 0.2 3.1 2 1 1 3 3 3 0 Zic proteins zinc finger domain Scramblase PF03803.15 ORX90255.1 - 0.055 12.8 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Scramblase zf-C2HC_2 PF13913.6 ORX90255.1 - 0.074 13.0 0.3 0.074 13.0 0.3 3.4 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 ORX90255.1 - 0.092 12.7 8.0 2.8 7.9 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-CHY PF05495.12 ORX90255.1 - 0.092 13.3 10.2 0.062 13.8 4.0 2.4 1 1 1 2 2 2 0 CHY zinc finger HalOD2 PF18547.1 ORX90255.1 - 0.099 12.6 0.6 0.28 11.1 0.6 1.8 1 1 0 1 1 1 0 Halobacterial output domain 2 C1_4 PF07975.12 ORX90255.1 - 0.18 12.0 11.1 0.67 10.2 6.1 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zf_UBZ PF18439.1 ORX90255.1 - 0.58 9.8 6.4 2.9 7.6 0.4 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger IBR PF01485.21 ORX90255.1 - 0.8 10.0 10.0 0.097 12.9 3.5 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 ORX90255.1 - 3.3 7.7 9.1 5.5 7.0 3.9 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain MFS_1 PF07690.16 ORX90256.1 - 4.9e-20 71.8 26.1 7.3e-20 71.2 26.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90256.1 - 1e-14 54.5 6.1 1e-14 54.5 6.1 2.5 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORX90256.1 - 0.12 11.4 15.0 0.057 12.4 9.2 2.9 2 2 0 2 2 2 0 PUCC protein CPP1-like PF11833.8 ORX90256.1 - 1.7 8.2 4.2 1.2 8.7 1.5 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DJ-1_PfpI PF01965.24 ORX90258.1 - 0.001 18.9 0.3 0.75 9.6 0.0 2.7 1 1 1 2 2 2 2 DJ-1/PfpI family ThiJ_like PF17124.5 ORX90258.1 - 0.0014 18.4 0.2 0.0033 17.2 0.0 1.6 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX90258.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain DUF1100 PF06500.11 ORX90259.1 - 1.7e-12 46.9 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 ORX90259.1 - 1.7e-07 32.1 0.0 7.9e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORX90259.1 - 8e-07 29.2 0.0 1.6e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ORX90259.1 - 3.9e-06 26.3 0.1 3.9e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORX90259.1 - 1.1e-05 25.0 0.1 0.00011 21.8 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORX90259.1 - 1.4e-05 24.9 0.1 9.8e-05 22.1 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 ORX90259.1 - 1.4e-05 23.9 0.0 0.00094 17.9 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) UPF0227 PF05728.12 ORX90259.1 - 0.00029 20.8 0.0 0.0005 20.1 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 ORX90259.1 - 0.014 15.0 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_M75 PF09375.10 ORX90259.1 - 0.04 13.4 1.0 0.073 12.5 1.0 1.4 1 0 0 1 1 1 0 Imelysin Peripla_BP_6 PF13458.6 ORX90259.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_2 PF02230.16 ORX90259.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DJ-1_PfpI PF01965.24 ORX90260.1 - 2.1e-08 34.1 0.0 7.9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX90260.1 - 0.0014 18.4 0.1 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX90260.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain NAP PF00956.18 ORX90266.1 - 3.1e-25 88.9 13.1 7.2e-20 71.3 5.8 3.4 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 ORX90266.1 - 0.85 9.9 4.8 0.24 11.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WD40 PF00400.32 ORX90267.1 - 2.9e-16 59.5 1.1 4.5e-07 30.5 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90267.1 - 1.5e-06 28.4 0.1 0.0003 21.0 0.0 3.7 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX90267.1 - 1.3e-05 24.3 2.1 0.00098 18.2 0.1 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 ORX90267.1 - 0.0042 16.4 0.0 0.088 12.0 0.0 2.4 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ORX90267.1 - 0.036 13.7 0.2 2.3 7.7 0.0 2.8 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region VCBS PF13517.6 ORX90267.1 - 0.12 13.0 0.9 1.3 9.7 0.2 3.0 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Tfb5 PF06331.12 ORX90268.1 - 1.9e-14 53.4 0.3 2.1e-14 53.3 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 zf-CCCH PF00642.24 ORX90269.1 - 0.001 18.9 1.8 0.001 18.9 1.8 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORX90269.1 - 0.004 17.8 0.0 0.0077 16.9 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 ORX90269.1 - 0.011 15.5 3.2 0.02 14.7 3.2 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX90269.1 - 0.032 14.3 2.2 0.059 13.4 2.2 1.5 1 0 0 1 1 1 0 Zinc finger domain ESX-1_EspG PF14011.6 ORX90269.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 EspG family zf-CCCH_4 PF18044.1 ORX90270.1 - 7.9e-18 63.8 18.4 6.6e-09 35.4 4.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX90270.1 - 1.3e-14 53.7 24.6 3.4e-07 30.1 9.6 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORX90270.1 - 2.5e-14 52.8 13.7 1.8e-07 30.9 5.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.6 ORX90270.1 - 4e-10 39.8 1.5 8.6e-07 29.1 0.5 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Torus PF16131.5 ORX90270.1 - 7.1e-10 39.5 0.7 7.7e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Torus domain Ank_2 PF12796.7 ORX90270.1 - 9.9e-08 32.5 0.2 3.8e-07 30.6 0.2 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX90270.1 - 4.3e-07 30.1 0.0 1.5e-06 28.4 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ORX90270.1 - 1.1e-06 29.0 0.0 2.7e-05 24.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX90270.1 - 1.9e-05 24.7 0.1 0.00037 20.7 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat zf-CCCH_2 PF14608.6 ORX90270.1 - 0.00036 20.9 18.8 0.055 14.0 3.0 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ORX90270.1 - 0.52 10.6 10.1 4.9 7.4 10.1 2.1 1 1 0 1 1 1 0 Zinc-finger containing family EF-hand_7 PF13499.6 ORX90272.1 - 9e-25 86.9 6.9 5.5e-17 62.0 0.6 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORX90272.1 - 5.1e-24 82.0 9.9 4.2e-07 29.0 0.3 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 ORX90272.1 - 1.7e-23 80.5 4.5 1.5e-06 27.7 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 ORX90272.1 - 2.2e-18 64.9 10.5 2.5e-07 29.9 0.3 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 ORX90272.1 - 8.9e-13 47.9 7.5 2.1e-06 27.4 0.8 3.6 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 ORX90272.1 - 3.6e-07 30.1 3.7 0.066 13.2 0.1 3.8 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORX90272.1 - 5.8e-05 23.4 1.1 0.12 12.7 0.2 3.3 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORX90272.1 - 0.0012 19.1 0.3 0.36 11.2 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 ORX90272.1 - 0.006 16.4 0.9 1.4 8.8 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_14 PF17959.1 ORX90272.1 - 0.024 15.0 0.5 13 6.2 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DUF1707 PF08044.11 ORX90272.1 - 0.17 11.9 0.0 0.94 9.6 0.0 2.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) Peptidase_M76 PF09768.9 ORX90273.1 - 4.8e-67 225.0 5.1 5.7e-67 224.8 5.1 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 ORX90273.1 - 0.0012 18.7 1.8 0.0018 18.1 1.5 1.5 1 1 0 1 1 1 1 SprT-like family DUF3725 PF12523.8 ORX90273.1 - 0.016 15.5 0.9 3.6 8.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3725) C2 PF00168.30 ORX90274.1 - 3.7e-07 30.4 0.0 6.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain FYRN PF05964.14 ORX90275.1 - 3.9e-20 71.4 0.3 6.4e-20 70.7 0.3 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORX90275.1 - 5.8e-16 58.4 0.0 1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus P34-Arc PF04045.14 ORX90276.1 - 6.3e-106 353.5 1.6 8.8e-106 353.0 1.6 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ribosomal_L1 PF00687.21 ORX90277.1 - 1.1e-47 162.4 1.7 1.3e-47 162.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 ORX90277.1 - 0.2 11.7 2.5 0.32 11.1 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function SSP160 PF06933.11 ORX90278.1 - 0.012 13.9 0.0 0.015 13.5 0.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Coprogen_oxidas PF01218.18 ORX90280.1 - 1.2e-135 451.0 0.0 1.4e-135 450.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Cyclin PF08613.11 ORX90281.1 - 9e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX90281.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Sugar_tr PF00083.24 ORX90282.1 - 3.6e-47 161.3 21.0 1.1e-26 93.8 10.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORX90282.1 - 1.3e-16 60.5 34.8 8.5e-09 34.8 10.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF262 PF03235.14 ORX90283.1 - 1.6e-14 54.6 0.0 6e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function DUF262 Abhydrolase_2 PF02230.16 ORX90284.1 - 1.5e-66 224.3 0.0 1.9e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORX90284.1 - 1.6e-07 30.9 0.2 0.019 14.2 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 ORX90284.1 - 1.6e-06 27.8 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 ORX90284.1 - 1.2e-05 25.1 0.0 6.3e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ORX90284.1 - 1.9e-05 25.4 0.0 2.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX90284.1 - 0.00013 21.5 0.0 0.00061 19.3 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORX90284.1 - 0.0013 18.7 0.0 0.34 10.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 ORX90284.1 - 0.012 15.1 0.1 8.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORX90284.1 - 0.031 13.9 1.4 0.47 10.0 1.2 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORX90284.1 - 0.097 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 ORX90284.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Zn_ribbon_17 PF17120.5 ORX90285.1 - 4.5e-12 45.4 10.0 1.1e-11 44.2 10.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 ORX90285.1 - 6.8e-06 26.3 12.5 9.9e-05 22.5 12.4 2.2 1 1 0 1 1 1 1 Zinc-ribbon like family zf-rbx1 PF12678.7 ORX90285.1 - 0.54 10.6 7.7 1.3 9.4 7.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 ORX90285.1 - 0.85 9.7 7.3 1.9 8.5 7.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 ORX90287.1 - 4.6e-12 46.3 13.8 0.0026 18.6 0.7 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Rav1p_C PF12234.8 ORX90287.1 - 0.2 10.0 0.1 0.49 8.7 0.0 1.6 2 0 0 2 2 2 0 RAVE protein 1 C terminal RNA_pol_L_2 PF13656.6 ORX90288.1 - 3.9e-27 93.8 0.0 4.7e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORX90288.1 - 2.6e-08 33.2 0.0 4.7e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Bac_small_YrzI PF09501.10 ORX90288.1 - 0.029 14.5 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DnaJ PF00226.31 ORX90289.1 - 3e-25 88.1 1.5 4.2e-25 87.7 1.5 1.2 1 0 0 1 1 1 1 DnaJ domain Bact_transglu_N PF08379.10 ORX90289.1 - 0.09 13.7 0.8 0.15 13.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region DUF4124 PF13511.6 ORX90289.1 - 0.39 11.1 1.1 0.69 10.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) ILVD_EDD PF00920.21 ORX90290.1 - 4.3e-222 738.3 0.9 5e-222 738.1 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 ORX90290.1 - 0.023 14.9 0.2 2.6 8.4 0.0 2.9 3 0 0 3 3 3 0 FeoA domain EF-hand_1 PF00036.32 ORX90291.1 - 1.1e-40 134.1 14.9 2.4e-10 39.2 1.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX90291.1 - 6e-36 122.7 4.7 6.9e-19 68.1 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX90291.1 - 2.1e-31 105.2 9.5 2.9e-09 36.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORX90291.1 - 7.7e-31 105.7 13.3 1.4e-14 53.6 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORX90291.1 - 7.3e-26 88.5 12.5 9.6e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORX90291.1 - 2.6e-16 59.7 0.3 7.1e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORX90291.1 - 8.2e-10 38.6 1.7 7.1e-05 22.7 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORX90291.1 - 7.4e-09 35.9 0.1 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ORX90291.1 - 3.8e-06 27.0 2.6 0.02 15.1 0.5 3.1 1 1 3 4 4 4 3 Dockerin type I domain EF-hand_11 PF08976.11 ORX90291.1 - 4.4e-06 27.5 0.0 0.00022 22.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 ORX90291.1 - 3.2e-05 23.9 0.4 0.11 12.5 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 ORX90291.1 - 5.5e-05 23.9 0.5 0.36 11.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) EFhand_Ca_insen PF08726.10 ORX90291.1 - 0.00012 22.1 1.4 0.00086 19.4 0.2 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 ORX90291.1 - 0.0012 19.3 0.0 0.42 11.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Caleosin PF05042.13 ORX90291.1 - 0.0015 18.5 1.0 0.82 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 ORX90291.1 - 0.0048 16.9 0.7 0.9 9.5 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 ORX90291.1 - 0.0058 17.0 0.5 1.4 9.3 0.1 2.8 2 1 1 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 ORX90291.1 - 0.0079 16.3 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 ORX90291.1 - 0.0087 15.9 1.0 0.9 9.4 0.1 2.3 1 1 1 2 2 2 1 SurA N-terminal domain DUF5580 PF17743.1 ORX90291.1 - 0.016 13.8 0.0 0.016 13.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF1103 PF06513.11 ORX90291.1 - 0.028 14.1 2.8 0.032 13.8 2.8 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) EF-hand_14 PF17959.1 ORX90291.1 - 0.066 13.6 0.2 15 6.0 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain RuvA_C PF07499.13 ORX90291.1 - 0.12 12.9 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain GPHH PF16905.5 ORX90291.1 - 0.14 11.9 0.0 12 5.7 0.0 3.3 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated Spore_III_AB PF09548.10 ORX90291.1 - 0.17 12.0 0.5 0.34 11.0 0.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FGAR-AT_linker PF18072.1 ORX90291.1 - 0.19 12.3 0.4 6.3 7.4 0.0 2.6 2 2 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain SapB_1 PF05184.15 ORX90291.1 - 0.43 10.7 3.3 27 4.9 0.1 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 NAC PF01849.18 ORX90292.1 - 1.4e-22 79.4 0.5 2.5e-22 78.6 0.5 1.4 1 0 0 1 1 1 1 NAC domain Peptidase_C39 PF03412.15 ORX90292.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family ArfGap PF01412.18 ORX90293.1 - 3e-36 124.1 1.8 4.2e-36 123.6 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF3605 PF12239.8 ORX90294.1 - 1.4e-24 87.1 3.8 3.2e-22 79.5 3.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) LMWPc PF01451.21 ORX90295.1 - 3.8e-46 157.0 0.0 4.3e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Mem_trans PF03547.18 ORX90296.1 - 2.4e-13 49.3 0.5 3.1e-13 48.9 0.5 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF5320 PF17253.2 ORX90297.1 - 0.61 11.2 57.4 58 4.8 5.5 6.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Ribosomal_S3_C PF00189.20 ORX90298.1 - 2.5e-23 82.4 1.1 1e-22 80.4 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORX90298.1 - 1.3e-12 47.4 0.1 2.6e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORX90298.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DSPc PF00782.20 ORX90299.1 - 1.6e-36 125.1 0.0 2.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX90299.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glyco_hydro_16 PF00722.21 ORX90301.1 - 1.3e-33 116.0 0.9 1.5e-33 115.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_25 PF13649.6 ORX90302.1 - 3.7e-13 50.0 0.0 1.4e-12 48.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX90302.1 - 3.8e-12 46.7 0.0 1.1e-11 45.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX90302.1 - 2.7e-11 43.6 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX90302.1 - 7.5e-11 42.0 0.0 1.9e-09 37.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX90302.1 - 0.00036 19.9 0.0 0.0021 17.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORX90302.1 - 0.0023 18.7 0.0 0.0089 16.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORX90302.1 - 0.0031 16.8 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ORX90302.1 - 0.013 15.0 0.0 0.13 11.7 0.0 2.4 2 1 0 3 3 3 0 Putative methyltransferase FtsJ PF01728.19 ORX90302.1 - 0.016 15.4 0.0 0.046 13.8 0.0 1.7 2 1 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 ORX90302.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NicO PF03824.16 ORX90303.1 - 2.2e-53 181.5 3.7 2.5e-53 181.3 3.7 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein MHYT PF03707.16 ORX90303.1 - 0.15 12.3 0.3 0.15 12.3 0.3 2.5 2 1 1 3 3 3 0 Bacterial signalling protein N terminal repeat NicO PF03824.16 ORX90304.1 - 8.3e-85 284.5 12.9 8.3e-85 284.5 12.9 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF4028 PF13220.6 ORX90307.1 - 3.5 7.5 20.2 4.2 7.2 0.5 6.3 3 2 4 7 7 7 0 Protein of unknown function (DUF4028) CBAH PF02275.18 ORX90308.1 - 0.014 15.1 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family CHAP PF05257.16 ORX90309.1 - 1.4e-09 38.4 5.9 1.4e-09 38.4 5.9 2.3 1 1 1 2 2 2 1 CHAP domain LPMO_10 PF03067.15 ORX90310.1 - 4.6e-05 24.1 0.0 8.7e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX90310.1 - 0.008 16.1 0.0 0.013 15.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Dehyd-heme_bind PF09098.10 ORX90311.1 - 0.015 14.9 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding VEK-30 PF12107.8 ORX90311.1 - 0.31 11.0 2.2 8.2 6.5 0.0 3.0 3 0 0 3 3 3 0 Plasminogen (Pg) ligand in fibrinolytic pathway Lipase_3 PF01764.25 ORX90312.1 - 9.8e-27 93.6 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX90312.1 - 7.2e-06 25.7 0.0 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORX90312.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX90312.1 - 0.0053 17.4 0.0 0.0072 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORX90312.1 - 0.031 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 ORX90312.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ORX90312.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Clathrin_lg_ch PF01086.17 ORX90313.1 - 9.7e-43 146.9 7.8 2.7e-42 145.4 7.8 1.7 1 1 0 1 1 1 1 Clathrin light chain rve_3 PF13683.6 ORX90313.1 - 0.13 12.1 0.8 0.6 9.9 0.3 2.1 2 0 0 2 2 2 0 Integrase core domain COX6C PF02937.15 ORX90313.1 - 0.21 11.7 0.5 0.4 10.9 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc C5HCH PF17982.1 ORX90314.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain HATPase_c PF02518.26 ORX90315.1 - 9.2e-53 177.5 0.7 9.6e-27 93.7 0.1 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX90315.1 - 2.9e-52 175.6 0.7 4.2e-27 94.5 0.1 3.3 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 ORX90315.1 - 4.1e-31 106.8 5.6 3.4e-15 55.8 0.7 2.8 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain GAF PF01590.26 ORX90315.1 - 1.2e-07 32.4 0.0 3.4e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ORX90315.1 - 0.00015 22.1 0.0 0.00051 20.4 0.0 2.0 2 1 0 2 2 2 1 GAF domain GAF_2 PF13185.6 ORX90315.1 - 0.00027 21.2 0.0 0.0011 19.3 0.0 2.1 1 1 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 ORX90315.1 - 0.0003 20.6 0.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PH_TFIIH PF08567.11 ORX90315.1 - 0.034 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain IF4E PF01652.18 ORX90315.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E RGS PF00615.19 ORX90316.1 - 5.5e-14 52.5 1.6 7.4e-14 52.0 0.3 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORX90316.1 - 0.0026 17.5 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain DUF2254 PF10011.9 ORX90316.1 - 5 5.8 5.6 9.7 4.9 5.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) FancD2 PF14631.6 ORX90317.1 - 4.5e-223 743.5 32.1 4.9e-152 508.1 19.2 3.1 1 1 1 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 ORX90317.1 - 2.3e-05 24.8 0.0 2.3e-05 24.8 0.0 3.0 4 0 0 4 4 4 1 FANCI solenoid 2 Condensin2nSMC PF12422.8 ORX90317.1 - 0.029 14.5 0.1 0.19 11.9 0.1 2.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit PHAT PF09246.10 ORX90317.1 - 0.1 12.5 0.2 12 5.8 0.0 3.5 3 0 0 3 3 3 0 PHAT zf-C2H2_assoc2 PF16624.5 ORX90317.1 - 0.73 10.9 9.6 1.8 9.7 3.2 2.9 2 0 0 2 2 2 0 Unstructured region upstream of a zinc-finger Ras PF00071.22 ORX90318.1 - 1.1e-48 164.9 0.0 1.3e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90318.1 - 1.3e-29 102.8 0.1 3.2e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90318.1 - 2.1e-10 40.3 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 ORX90318.1 - 0.00024 21.4 0.2 0.0015 18.9 0.2 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 ORX90318.1 - 0.0012 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX90318.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORX90318.1 - 0.009 15.2 1.5 1.2 8.2 0.1 2.3 2 1 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 ORX90318.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 ORX90318.1 - 0.022 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 ORX90318.1 - 0.025 14.5 0.1 8 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 ORX90318.1 - 0.035 13.7 0.3 0.21 11.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 ORX90318.1 - 0.037 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 ORX90318.1 - 0.06 13.1 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORX90318.1 - 0.084 12.9 0.1 0.2 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ORX90318.1 - 0.092 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain O_Spanin_T7 PF17531.2 ORX90318.1 - 0.12 12.5 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 outer-membrane spanin sub-unit AAA_33 PF13671.6 ORX90318.1 - 0.12 12.5 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 ORX90319.1 - 1.1e-51 175.6 0.0 1.8e-51 174.9 0.0 1.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4864 PF16156.5 ORX90319.1 - 0.059 14.1 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Cu-oxidase_3 PF07732.15 ORX90320.1 - 9.4e-10 38.5 16.3 0.079 13.0 0.1 7.3 7 0 0 7 7 7 5 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX90320.1 - 2.2e-07 30.7 15.4 0.0019 18.0 6.5 5.4 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 ORX90320.1 - 0.0068 16.5 0.1 0.045 13.9 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX90321.1 - 1.7e-11 44.1 15.7 0.013 15.5 0.1 7.1 7 0 0 7 7 7 5 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX90321.1 - 1.9e-08 34.2 14.3 0.0029 17.4 4.5 5.5 4 1 0 4 4 4 4 Multicopper oxidase Cu-oxidase PF00394.22 ORX90321.1 - 0.029 14.5 0.0 6.3 6.9 0.0 3.2 3 0 0 3 3 3 0 Multicopper oxidase DEAD PF00270.29 ORX90322.1 - 9.3e-47 159.1 0.0 1.6e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90322.1 - 2.6e-32 111.5 0.0 8.4e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90322.1 - 0.00092 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORX90322.1 - 0.05 12.4 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 ORX90322.1 - 0.077 13.3 0.2 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 ORX90322.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase OMPdecase PF00215.24 ORX90323.1 - 6.8e-77 258.1 0.0 7.8e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NuiA PF07924.11 ORX90324.1 - 2.9e-15 56.8 2.1 4.6e-15 56.2 0.1 2.0 2 0 0 2 2 2 1 Nuclease A inhibitor-like protein Smg4_UPF3 PF03467.15 ORX90324.1 - 0.011 15.8 3.2 0.02 14.9 3.2 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family 6PGD PF00393.19 ORX90325.1 - 4.9e-127 423.3 0.0 6.6e-127 422.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORX90325.1 - 9.1e-52 175.4 0.0 1.3e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORX90325.1 - 0.0025 18.0 0.0 0.069 13.4 0.0 2.4 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORX90325.1 - 0.016 15.8 0.2 0.031 14.9 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DNA_pol3_beta PF00712.19 ORX90325.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain CoatB PF10389.9 ORX90325.1 - 0.28 11.0 3.1 1.4 8.8 0.4 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B UCH PF00443.29 ORX90326.1 - 5.7e-51 173.5 0.0 7e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX90326.1 - 1.3e-10 41.4 0.8 5.7e-10 39.3 0.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORX90326.1 - 9.5e-07 28.5 0.0 3.7e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 ORX90326.1 - 0.0011 18.5 1.3 0.0046 16.5 0.1 2.3 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase BAR_2 PF10455.9 ORX90327.1 - 2.9e-48 164.5 2.2 9.1e-48 162.8 2.2 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORX90327.1 - 8.1e-21 74.7 3.7 1.2e-20 74.2 3.7 1.2 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORX90327.1 - 7.3e-07 29.1 2.6 1.4e-06 28.2 2.6 1.7 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 ORX90327.1 - 0.0074 15.9 4.4 0.063 12.8 0.6 2.4 2 1 1 3 3 3 2 Arfaptin-like domain DUF743 PF05332.11 ORX90327.1 - 0.054 13.6 0.4 0.14 12.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF743) ACPS PF01648.20 ORX90328.1 - 5.2e-15 55.6 0.0 5.9e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily tRNA_m1G_MT PF01746.21 ORX90329.1 - 4e-20 72.3 0.0 6.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PRP3 PF08572.10 ORX90329.1 - 0.0062 16.3 5.0 0.011 15.4 5.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF3847 PF12958.7 ORX90329.1 - 0.56 10.4 5.8 0.75 10.0 4.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) SLBP_RNA_bind PF15247.6 ORX90330.1 - 1.7 8.8 7.2 1.6 8.9 0.1 2.7 2 1 2 4 4 4 0 Histone RNA hairpin-binding protein RNA-binding domain RRM_9 PF18444.1 ORX90331.1 - 1.3e-17 63.4 0.0 2.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 ORX90331.1 - 4.2e-16 58.3 0.2 8.2e-16 57.4 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 ORX90331.1 - 2.8e-06 26.9 0.0 6.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 ORX90331.1 - 3.6e-06 27.5 0.4 1.6e-05 25.5 0.1 2.2 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 ORX90331.1 - 0.019 14.7 4.0 0.073 12.8 4.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 ORX90331.1 - 0.093 13.2 8.8 0.94 10.0 3.2 2.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 ORX90331.1 - 0.11 12.3 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain zf-H2C2_2 PF13465.6 ORX90332.1 - 8.1e-09 35.5 21.0 2.6e-06 27.6 4.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX90332.1 - 2.2e-07 31.0 19.4 8.9e-05 22.7 3.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90332.1 - 0.00071 20.2 14.9 0.03 15.2 2.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORX90332.1 - 0.036 14.5 2.3 0.085 13.3 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX90332.1 - 0.056 13.8 0.9 0.17 12.2 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX90332.1 - 7.2 6.7 16.0 1.6 8.9 2.7 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger Mito_carr PF00153.27 ORX90334.1 - 2e-77 255.2 0.3 1.4e-25 89.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX90334.1 - 1.1e-05 24.7 0.4 0.36 10.0 0.0 3.3 2 1 1 3 3 3 2 Gammaproteobacterial serine protease Longin PF13774.6 ORX90336.1 - 8.8e-29 99.4 0.2 1.4e-28 98.7 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ORX90336.1 - 3.3e-16 58.8 0.1 6.9e-16 57.8 0.0 1.6 2 0 0 2 2 2 1 Synaptobrevin SLM4 PF16818.5 ORX90336.1 - 0.058 13.3 3.4 0.84 9.6 0.3 2.1 1 1 1 2 2 2 0 Protein SLM4 Lectin_N PF03954.14 ORX90336.1 - 0.074 12.8 1.3 0.12 12.1 1.3 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Imm70 PF15601.6 ORX90336.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 70 CDI PF02234.19 ORX90337.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.8 4 0 0 4 4 4 0 Cyclin-dependent kinase inhibitor Forkhead PF00250.18 ORX90338.1 - 1.7e-31 108.3 0.4 2.1e-31 108.0 0.4 1.1 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 ORX90338.1 - 0.083 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 linker histone H1 and H5 family Na_Ca_ex PF01699.24 ORX90339.1 - 4.4e-20 72.2 29.8 3.1e-14 53.2 14.9 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 ORX90339.1 - 1e-16 61.3 8.0 1e-16 61.3 8.0 3.9 4 0 0 4 4 4 1 Inner membrane component domain Cript PF10235.9 ORX90339.1 - 0.16 12.6 0.1 0.16 12.6 0.1 1.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Macoilin PF09726.9 ORX90339.1 - 0.42 9.1 9.1 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Macoilin family LRR_4 PF12799.7 ORX90340.1 - 2.1e-28 97.9 53.0 6.6e-07 29.6 3.2 6.6 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX90340.1 - 1.1e-26 92.3 49.0 1.8e-10 40.4 7.2 5.4 3 1 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 ORX90340.1 - 7.7e-11 41.0 41.0 0.018 15.5 0.3 10.9 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 ORX90340.1 - 6.8e-05 22.4 16.8 0.014 14.9 4.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT_2 PF08263.12 ORX90340.1 - 0.03 14.6 4.8 0.03 14.6 4.8 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Dict-STAT-coil PF09267.10 ORX90340.1 - 2.3 8.6 6.8 7.4 7.0 0.0 3.3 1 1 0 2 2 2 0 Dictyostelium STAT, coiled coil DAGK_cat PF00781.24 ORX90341.1 - 1.2e-25 89.5 0.0 1.8e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4451 PF14616.6 ORX90343.1 - 4.7e-28 97.8 2.1 5.6e-28 97.6 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF4709 PF15821.5 ORX90344.1 - 0.23 11.8 8.8 6 7.2 0.2 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4709) DUF948 PF06103.11 ORX90344.1 - 0.28 11.5 5.7 7.2 6.9 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2408 PF10303.9 ORX90344.1 - 0.34 11.5 10.6 4.4 7.9 5.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) CC2-LZ PF16516.5 ORX90344.1 - 3.5 8.0 7.1 0.32 11.4 0.5 2.6 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator H-kinase_dim PF02895.14 ORX90344.1 - 4.5 7.7 7.1 0.87 10.0 0.3 3.1 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF4621 PF15414.6 ORX90348.1 - 0.16 10.8 0.9 0.24 10.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) SlpA PF03217.14 ORX90348.1 - 8.6 7.0 9.3 17 6.1 0.4 2.9 3 0 0 3 3 3 0 Surface later protein A domain FUSC_2 PF13515.6 ORX90350.1 - 3.6e-19 69.1 9.7 3.6e-19 69.1 9.7 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORX90350.1 - 5.4e-10 38.5 7.2 4.7e-09 35.4 1.8 3.1 3 0 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 ORX90350.1 - 9.4e-10 38.7 0.6 7.1e-09 35.8 0.1 2.4 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 ORX90350.1 - 5.5e-08 32.1 11.3 1.7e-06 27.2 0.3 2.6 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2_N PF10337.9 ORX90350.1 - 0.0016 17.5 8.8 0.003 16.7 2.9 2.4 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal PS_pyruv_trans PF04230.13 ORX90350.1 - 0.14 12.1 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase ArAE_1 PF06081.11 ORX90350.1 - 1.4 9.0 14.8 0.018 15.2 3.4 3.2 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 FAD_binding_2 PF00890.24 ORX90351.1 - 6.1e-81 272.6 0.1 7.4e-81 272.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 ORX90351.1 - 9.7e-24 83.3 0.0 3.7e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ORX90351.1 - 2.7e-15 56.8 0.0 4.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORX90351.1 - 7.5e-09 35.4 0.8 1.9e-08 34.1 0.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX90351.1 - 2.7e-08 33.4 0.4 4.5e-07 29.4 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX90351.1 - 8e-08 32.4 0.8 7.9e-07 29.2 0.2 2.9 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX90351.1 - 1.4e-06 27.8 0.1 0.0012 18.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX90351.1 - 3.6e-06 25.9 4.1 0.00087 18.1 0.4 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 ORX90351.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORX90351.1 - 8.1e-05 23.1 2.1 0.038 14.5 0.6 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX90351.1 - 9.1e-05 21.8 0.4 0.0035 16.6 0.3 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 ORX90351.1 - 0.00037 19.7 0.3 0.0094 15.1 0.2 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORX90351.1 - 0.0033 16.7 0.3 0.006 15.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 ORX90351.1 - 0.011 15.8 0.2 0.098 12.6 0.2 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ORX90351.1 - 0.069 13.6 0.1 0.17 12.4 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORX90351.1 - 0.085 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 ORX90351.1 - 0.14 11.4 0.1 0.44 9.8 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase CAP_N PF01213.19 ORX90351.1 - 8 5.8 7.5 14 5.1 7.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GST_C_3 PF14497.6 ORX90352.1 - 3.1e-12 46.5 0.7 7.4e-12 45.3 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX90352.1 - 5.3e-07 29.9 0.1 1.6e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORX90352.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX90352.1 - 0.002 18.3 0.0 0.003 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.24 ORX90354.1 - 7e-96 321.8 28.4 8.2e-96 321.6 28.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90354.1 - 5.9e-26 91.2 18.8 5.9e-26 91.2 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_47 PF01532.20 ORX90355.1 - 4.1e-166 553.4 0.0 4.6e-166 553.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mon2_C PF16206.5 ORX90356.1 - 2.6e-74 250.8 3.6 5.6e-50 170.3 0.2 3.4 1 1 1 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 ORX90356.1 - 5e-51 172.9 3.3 5e-51 172.9 3.3 3.0 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 ORX90356.1 - 7.2e-47 159.2 3.1 7.2e-47 159.2 3.1 3.7 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORX90356.1 - 3.6e-05 23.5 1.1 0.0066 16.3 0.0 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.22 ORX90356.1 - 0.11 12.8 0.1 28 5.3 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat DUF4653 PF15546.6 ORX90356.1 - 0.13 11.9 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Bcl-2 PF00452.19 ORX90356.1 - 0.14 12.9 0.1 1.5 9.6 0.0 2.8 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Herpes_ICP4_N PF03584.15 ORX90357.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region LIM_bind PF01803.16 ORX90358.1 - 1.9e-59 201.1 1.1 1.9e-59 201.1 1.1 1.5 2 0 0 2 2 2 1 LIM-domain binding protein Lactamase_B_2 PF12706.7 ORX90359.1 - 6.6e-37 127.0 0.0 1.1e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORX90359.1 - 1.6e-17 63.9 0.0 2.7e-16 59.9 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORX90359.1 - 0.042 13.9 7.7 1.4 8.9 4.2 3.4 2 2 1 3 3 3 0 Metallo-beta-lactamase superfamily HMGL-like PF00682.19 ORX90360.1 - 5.3e-61 206.5 0.0 6.1e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like PRA-PH PF01503.17 ORX90360.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Glyco_tran_28_C PF04101.16 ORX90361.1 - 2.4e-30 105.7 0.0 2.9e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 ORX90361.1 - 0.0011 18.4 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 PIF6 PF05341.11 ORX90361.1 - 0.048 13.8 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity factor 6 Epimerase_2 PF02350.19 ORX90361.1 - 0.15 10.9 0.0 0.58 9.0 0.0 1.8 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Polysacc_deac_1 PF01522.21 ORX90362.1 - 4.5e-35 120.2 0.0 1.6e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX90362.1 - 2.7e-05 23.6 0.0 5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 PACT_coil_coil PF10495.9 ORX90362.1 - 0.02 15.4 0.0 1.1 9.9 0.0 2.4 1 1 1 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Glyco_transf_92 PF01697.27 ORX90362.1 - 0.051 13.2 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 92 LacI PF00356.21 ORX90362.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, lacI family Polysacc_deac_1 PF01522.21 ORX90363.1 - 2.9e-31 107.9 0.0 5.2e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ADH_zinc_N PF00107.26 ORX90364.1 - 3.6e-29 101.4 0.0 6.8e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX90364.1 - 1.9e-23 84.0 0.0 2.9e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX90364.1 - 9.6e-11 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORX90364.1 - 0.0039 17.4 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 ORX90364.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF2855 PF11017.8 ORX90364.1 - 0.048 13.4 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Brix PF04427.18 ORX90365.1 - 1.1e-48 166.0 0.1 1.5e-48 165.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 ORX90365.1 - 0.52 10.2 20.6 0.69 9.9 20.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IBB PF01749.20 ORX90365.1 - 0.58 10.6 9.4 0.15 12.5 5.0 2.2 2 0 0 2 2 2 0 Importin beta binding domain BUD22 PF09073.10 ORX90365.1 - 1.6 8.0 25.1 0.2 10.9 21.0 1.6 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.11 ORX90365.1 - 3.9 7.0 17.0 5.8 6.4 17.0 1.4 1 0 0 1 1 1 0 PPP4R2 Ribosomal_S5 PF00333.20 ORX90366.1 - 4.7e-30 103.4 0.8 1.1e-29 102.2 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX90366.1 - 5.3e-26 89.9 0.1 8.5e-26 89.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORX90366.1 - 0.26 11.9 11.2 0.53 10.9 11.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PEX11 PF05648.14 ORX90367.1 - 1.4e-22 80.2 2.4 1.8e-22 79.9 2.4 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RCC1 PF00415.18 ORX90369.1 - 1.2e-51 173.1 7.9 1.5e-10 41.5 0.0 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORX90369.1 - 1.8e-27 94.5 22.8 2.1e-06 27.4 0.4 8.0 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 ORX90369.1 - 0.13 12.7 1.3 0.39 11.2 0.0 2.4 4 0 0 4 4 4 0 SUKH-3 immunity protein CP2 PF04516.15 ORX90371.1 - 1.2e-53 181.8 0.1 1.9e-53 181.1 0.1 1.2 1 0 0 1 1 1 1 CP2 transcription factor Sod_Fe_C PF02777.18 ORX90372.1 - 1.2e-28 99.3 0.2 1.7e-27 95.6 0.1 2.6 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORX90372.1 - 2.5e-08 34.3 0.4 4.2e-08 33.5 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFAP1 PF06991.11 ORX90374.1 - 6e-72 242.0 25.4 6e-72 242.0 25.4 2.6 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Evr1_Alr PF04777.13 ORX90375.1 - 4.7e-32 110.4 2.6 5.8e-32 110.1 0.6 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Pyrophosphatase PF00719.19 ORX90376.1 - 4.5e-58 195.6 0.3 6e-58 195.2 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase SRP40_C PF05022.12 ORX90377.1 - 3.2e-30 104.8 1.1 4.2e-30 104.4 1.1 1.1 1 0 0 1 1 1 1 SRP40, C-terminal domain Proteasome PF00227.26 ORX90378.1 - 2.9e-53 180.2 1.0 3.2e-53 180.1 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 ORX90378.1 - 4.1e-12 45.5 0.1 6.9e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature INT_SG_DDX_CT_C PF15300.6 ORX90378.1 - 0.059 13.2 0.2 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Proteasome PF00227.26 ORX90379.1 - 1.2e-26 93.4 0.2 1.4e-26 93.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Svf1_C PF17187.4 ORX90380.1 - 2.1e-39 135.0 0.7 3.6e-39 134.2 0.6 1.4 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORX90380.1 - 1.5e-22 80.4 0.1 2.7e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain MBG PF17883.1 ORX90380.1 - 0.00035 21.1 0.3 0.0019 18.8 0.0 2.1 2 0 0 2 2 2 1 MBG domain DUF945 PF06097.11 ORX90380.1 - 0.03 13.4 0.3 0.066 12.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) HMA PF00403.26 ORX90382.1 - 1e-17 64.3 0.3 1.1e-17 64.2 0.3 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 ORX90382.1 - 0.061 13.7 0.2 0.19 12.1 0.1 1.8 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain GnsAB_toxin PF08178.11 ORX90382.1 - 0.088 12.7 0.2 0.28 11.2 0.1 1.8 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system RRF PF01765.19 ORX90383.1 - 0.2 11.6 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Peptidase_S8 PF00082.22 ORX90389.1 - 1.4e-30 106.6 0.1 1.5e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORX90390.1 - 4.9e-12 46.5 0.1 1.1e-11 45.4 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain Peptidase_S8 PF00082.22 ORX90390.1 - 2.1e-10 40.4 0.1 1.3e-09 37.8 0.0 2.0 1 1 1 2 2 2 1 Subtilase family DUF4232 PF14016.6 ORX90390.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Peptidase_S8 PF00082.22 ORX90391.1 - 1.8e-50 171.9 0.2 2.5e-50 171.4 0.2 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORX90391.1 - 6.9e-08 33.2 0.1 1.8e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 Fn3-like domain DUF4232 PF14016.6 ORX90391.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) MYCBPAP PF14646.6 ORX90391.1 - 0.19 10.6 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family Peptidase_S8 PF00082.22 ORX90392.1 - 1.3e-49 169.1 0.1 1.8e-49 168.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORX90392.1 - 2.5e-12 47.5 0.1 4.2e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORX90392.1 - 0.0005 20.0 0.1 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 PA domain DUF4232 PF14016.6 ORX90392.1 - 0.0015 18.7 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) Lipase_3 PF01764.25 ORX90393.1 - 8.4e-16 58.1 0.0 1.7e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 ORX90393.1 - 1.2e-07 32.0 0.1 3.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain UPF0227 PF05728.12 ORX90393.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 ORX90393.1 - 0.038 13.5 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TraT PF05818.12 ORX90393.1 - 0.11 12.2 0.2 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein MFS_1 PF07690.16 ORX90394.1 - 6.9e-53 179.8 32.8 6.9e-53 179.8 32.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX90394.1 - 1.3e-10 40.8 13.5 1.3e-10 40.8 13.5 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 ORX90394.1 - 0.004 15.6 10.2 0.0064 14.9 10.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector DUF1269 PF06897.12 ORX90394.1 - 0.24 11.7 3.5 4.7 7.6 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) MFS_1_like PF12832.7 ORX90394.1 - 0.92 8.3 20.1 0.057 12.3 6.6 3.4 3 1 0 3 3 3 0 MFS_1 like family OATP PF03137.20 ORX90394.1 - 0.97 7.6 16.9 0.28 9.4 0.5 3.6 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ALO PF04030.14 ORX90396.1 - 2.1e-22 80.2 0.2 1.9e-15 57.4 0.1 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ORX90396.1 - 3.9e-22 78.5 2.6 3.9e-22 78.5 2.6 1.5 2 0 0 2 2 2 1 FAD binding domain ADH_zinc_N_2 PF13602.6 ORX90397.1 - 6.1e-18 66.2 0.0 9.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX90397.1 - 2.5e-14 53.4 0.0 3.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX90397.1 - 8.5e-09 35.3 0.0 2.5e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF5075 PF16825.5 ORX90398.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 IGP family C-type lectin domain tRNA-synt_His PF13393.6 ORX90398.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF2740 PF10872.8 ORX90400.1 - 0.018 14.9 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) NicO PF03824.16 ORX90401.1 - 2.2e-83 279.9 11.3 3.3e-83 279.3 11.3 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Sarcolipin PF05366.11 ORX90401.1 - 0.097 12.4 0.7 0.25 11.1 0.7 1.6 1 0 0 1 1 1 0 Sarcolipin TMEM171 PF15471.6 ORX90401.1 - 10 5.0 7.9 11 5.0 0.1 2.8 3 0 0 3 3 3 0 Transmembrane protein family 171 NicO PF03824.16 ORX90402.1 - 2.2e-83 279.9 11.3 3.3e-83 279.3 11.3 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Sarcolipin PF05366.11 ORX90402.1 - 0.098 12.4 0.7 0.25 11.1 0.7 1.6 1 0 0 1 1 1 0 Sarcolipin TMEM171 PF15471.6 ORX90402.1 - 10 5.0 7.9 11 5.0 0.1 2.8 3 0 0 3 3 3 0 Transmembrane protein family 171 fn3_PAP PF17808.1 ORX90403.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Mito_carr PF00153.27 ORX90404.1 - 1.1e-46 156.7 0.8 2.1e-19 69.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Class_IIIsignal PF04021.12 ORX90406.1 - 0.048 13.6 1.0 0.087 12.8 1.0 1.4 1 0 0 1 1 1 0 Class III signal peptide SpoIIID PF12116.8 ORX90406.1 - 0.054 13.6 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D RNA_pol PF00940.19 ORX90407.1 - 2.8e-181 602.9 0.0 3.8e-181 602.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 ORX90407.1 - 1e-81 275.0 0.2 1.6e-81 274.3 0.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 ORX90407.1 - 8.2e-08 32.3 0.0 2.3e-05 24.5 0.0 2.8 2 1 1 3 3 3 2 PPR repeat family PPR_1 PF12854.7 ORX90407.1 - 0.019 14.6 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 PPR repeat PPR PF01535.20 ORX90407.1 - 0.032 14.5 0.1 18 5.9 0.0 3.3 3 0 0 3 3 3 0 PPR repeat Macoilin PF09726.9 ORX90408.1 - 5.6 5.4 15.2 6.1 5.3 15.2 1.1 1 0 0 1 1 1 0 Macoilin family ydhR PF08803.11 ORX90409.1 - 4.6e-39 132.2 0.0 5.1e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR DUF4448 PF14610.6 ORX90410.1 - 2e-06 27.7 0.0 4.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4690 PF15756.5 ORX90410.1 - 0.035 14.7 0.4 0.097 13.3 0.4 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Cytomega_UL84 PF06284.11 ORX90411.1 - 0.055 11.9 2.5 0.059 11.8 2.5 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein ORC6 PF05460.13 ORX90411.1 - 0.18 11.0 10.0 0.2 10.9 10.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3583 PF12126.8 ORX90411.1 - 1 8.8 8.2 1.5 8.2 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF3391 PF11871.8 ORX90411.1 - 2.1 8.9 9.4 3.5 8.2 9.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CCDC53 PF10152.9 ORX90411.1 - 2.5 8.5 8.0 3.1 8.2 8.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Pox_Ag35 PF03286.14 ORX90411.1 - 3.9 7.2 8.8 5.5 6.7 8.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TAFII28 PF04719.14 ORX90412.1 - 1.5e-31 108.3 0.0 1.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF5501 PF17605.2 ORX90412.1 - 0.053 13.9 0.0 0.089 13.2 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5501) MMS1_N PF10433.9 ORX90414.1 - 3.9e-106 355.6 0.0 1.1e-105 354.1 0.1 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORX90414.1 - 2.7e-57 194.5 0.0 3.2e-55 187.7 0.0 2.6 1 1 0 1 1 1 1 CPSF A subunit region TerD PF02342.18 ORX90414.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 TerD domain Cyclin PF08613.11 ORX90415.1 - 4.3e-09 36.9 0.1 5.9e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX90415.1 - 1.4e-05 24.8 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX90416.1 - 1.6e-07 31.8 0.0 2.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX90416.1 - 2.1e-06 27.5 0.0 4.5e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF2408 PF10303.9 ORX90418.1 - 4.9e-52 176.1 12.1 1.3e-28 100.2 0.3 5.3 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) PTRF_SDPR PF15237.6 ORX90418.1 - 0.091 12.4 3.1 1.1 8.8 0.3 2.3 2 0 0 2 2 2 0 PTRF/SDPR family TBCC_N PF16752.5 ORX90418.1 - 0.55 10.7 2.3 4.5 7.8 0.0 3.0 3 1 1 4 4 4 0 Tubulin-specific chaperone C N-terminal domain Nucleos_tra2_C PF07662.13 ORX90419.1 - 1.6e-75 253.5 7.2 1.6e-75 253.5 7.2 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX90419.1 - 3e-24 85.4 5.1 3e-24 85.4 5.1 3.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX90419.1 - 0.0041 17.4 8.9 0.0041 17.4 8.9 4.3 3 2 0 3 3 3 1 Nucleoside recognition Ycf9 PF01737.17 ORX90419.1 - 0.083 12.8 9.5 0.15 11.9 0.3 4.1 4 0 0 4 4 4 0 YCF9 TPT PF03151.16 ORX90425.1 - 1e-41 143.2 25.3 1.2e-41 142.9 25.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORX90425.1 - 9.5e-11 41.4 26.7 1.2e-10 41.2 26.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORX90425.1 - 3.9e-10 40.0 33.6 5.7e-05 23.3 11.5 2.3 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ORX90426.1 - 5.4e-42 144.1 24.8 6.8e-42 143.8 24.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORX90426.1 - 3.7e-11 42.8 26.5 4.6e-11 42.5 26.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORX90426.1 - 1.3e-09 38.4 33.2 5.9e-05 23.3 11.0 2.3 2 1 0 2 2 2 2 EamA-like transporter family HSP20 PF00011.21 ORX90428.1 - 1e-22 80.2 0.2 1.3e-22 79.9 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORX90428.1 - 1.2e-13 50.4 0.0 1.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 ORX90428.1 - 5.5e-06 27.3 0.3 8.2e-05 23.5 0.1 1.8 1 1 1 2 2 2 2 CS domain Iwr1 PF08574.10 ORX90429.1 - 9.8e-12 45.7 14.3 9.8e-12 45.7 14.3 3.0 3 1 0 3 3 3 1 Transcription factor Iwr1 BSD PF03909.17 ORX90430.1 - 6.9e-17 61.2 0.4 1.6e-09 37.6 0.0 3.0 2 0 0 2 2 2 2 BSD domain DUF1993 PF09351.10 ORX90430.1 - 0.01 16.0 1.0 0.021 15.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Ribosomal_L39 PF00832.20 ORX90431.1 - 5.1e-23 80.4 10.8 5.8e-23 80.3 10.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein RWD PF05773.22 ORX90432.1 - 1.8e-22 79.8 7.2 3.8e-22 78.8 7.2 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 ORX90432.1 - 4.1e-06 27.2 7.6 1.5e-05 25.4 7.6 1.9 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 CcmE PF03100.15 ORX90432.1 - 0.11 12.5 0.0 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 CcmE Peroxidase_2 PF01328.17 ORX90432.1 - 0.13 12.7 0.3 0.24 11.9 0.3 1.6 1 1 0 1 1 1 0 Peroxidase, family 2 Aldo_ket_red PF00248.21 ORX90433.1 - 2.7e-49 168.0 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CPL PF08144.11 ORX90434.1 - 7.1e-44 149.6 6.4 1.7e-39 135.4 0.0 5.0 5 1 0 5 5 5 2 CPL (NUC119) domain PUF PF00806.19 ORX90434.1 - 0.011 15.4 0.4 4.5 7.2 0.0 4.5 5 0 0 5 5 5 0 Pumilio-family RNA binding repeat DUF732 PF05305.14 ORX90434.1 - 0.055 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF3683 PF12447.8 ORX90434.1 - 0.072 13.2 0.2 4.9 7.3 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3683) DUF572 PF04502.13 ORX90434.1 - 0.099 12.3 5.3 0.19 11.3 5.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L11 PF00298.19 ORX90435.1 - 6.3e-29 100.3 0.1 1.1e-28 99.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 ORX90435.1 - 3.2e-28 97.4 0.5 4.9e-28 96.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Rep_fac-A_C PF08646.10 ORX90436.1 - 2.3e-55 186.4 3.2 4.6e-53 178.9 0.6 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 ORX90436.1 - 1.9e-39 133.5 1.0 6.7e-38 128.6 0.4 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 ORX90436.1 - 1.3e-30 105.3 0.5 3.7e-30 103.9 0.5 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 ORX90436.1 - 2.1e-12 46.8 0.4 5.1e-10 39.2 0.0 3.8 4 1 0 4 4 4 1 OB-fold nucleic acid binding domain BRCA-2_OB1 PF09103.10 ORX90436.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 POT1 PF02765.17 ORX90436.1 - 0.0034 17.2 1.6 0.015 15.2 0.0 2.6 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 ORX90436.1 - 0.0035 17.1 0.3 0.036 13.8 0.0 2.6 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DHHC PF01529.20 ORX90437.1 - 8.2e-39 132.8 14.0 9.6e-39 132.6 14.0 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.17 ORX90437.1 - 0.00037 20.2 0.4 0.00049 19.8 0.4 1.1 1 0 0 1 1 1 1 Yip1 domain PSI PF01437.25 ORX90437.1 - 0.0063 17.0 6.9 0.0063 17.0 6.9 1.5 2 0 0 2 2 2 1 Plexin repeat Imm17 PF15562.6 ORX90437.1 - 0.013 15.3 0.1 0.013 15.3 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 17 DUF92 PF01940.16 ORX90437.1 - 0.42 10.0 2.6 1.4 8.3 1.5 1.8 1 1 1 2 2 2 0 Integral membrane protein DUF92 RIO1 PF01163.22 ORX90438.1 - 2.9e-78 261.8 0.4 4.7e-78 261.1 0.4 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORX90438.1 - 0.00012 22.1 0.0 0.3 11.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORX90438.1 - 0.0042 16.5 0.5 0.37 10.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.12 ORX90438.1 - 0.028 13.5 0.4 0.069 12.2 0.3 1.6 1 1 1 2 2 2 0 Autophagy protein Apg17 Pkinase_fungal PF17667.1 ORX90438.1 - 0.037 12.8 0.1 0.061 12.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Rhodanese PF00581.20 ORX90439.1 - 2.2e-14 53.9 0.0 3.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Gifsy-2 PF13856.6 ORX90439.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 ATP-binding sugar transporter from pro-phage Pkinase PF00069.25 ORX90440.1 - 7.5e-14 51.7 0.0 9.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 ORX90440.1 - 5e-11 42.6 0.0 7.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORX90440.1 - 2e-08 33.9 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX90440.1 - 2.8e-08 34.0 0.0 0.0013 18.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 ORX90440.1 - 2.7e-06 26.9 0.0 3.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 ORX90440.1 - 0.0085 15.7 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YjbE PF11106.8 ORX90440.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE RNA_pol_Rpb4 PF03874.16 ORX90441.1 - 9.7e-28 97.0 4.9 1.2e-27 96.7 4.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ribosomal_L6 PF00347.23 ORX90442.1 - 1.5e-31 108.9 6.4 6e-17 62.1 1.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Exotox-A_cataly PF09009.10 ORX90442.1 - 0.062 13.0 0.1 1.1 9.0 0.1 2.5 2 1 1 3 3 3 0 Exotoxin A catalytic PQ-loop PF04193.14 ORX90443.1 - 2e-24 85.1 8.1 1.4e-12 47.2 0.5 2.8 3 0 0 3 3 3 2 PQ loop repeat COX2_TM PF02790.15 ORX90443.1 - 0.2 11.8 1.6 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Kinesin PF00225.23 ORX90444.1 - 4.3e-110 367.8 0.2 4.3e-110 367.8 0.2 2.5 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORX90444.1 - 2.1e-24 86.2 0.0 2.1e-24 86.2 0.0 3.6 3 1 1 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 ORX90444.1 - 1.2e-05 25.6 1.1 1.2e-05 25.6 1.1 6.2 3 1 2 6 6 6 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 ORX90444.1 - 2.2e-05 24.4 56.7 0.00069 19.5 9.9 4.9 2 1 4 6 6 6 5 Apolipoprotein A1/A4/E domain OmpH PF03938.14 ORX90444.1 - 0.15 12.4 63.0 0.32 11.3 3.9 6.4 2 2 4 6 6 6 0 Outer membrane protein (OmpH-like) DUF4455 PF14643.6 ORX90444.1 - 0.25 10.0 55.5 0.023 13.3 10.2 4.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4455) DUF2935 PF11155.8 ORX90444.1 - 3.4 8.0 25.2 33 4.8 1.6 5.7 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) RGS PF00615.19 ORX90445.1 - 6.5e-14 52.2 1.4 9e-14 51.8 1.4 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain PRD_Mga PF08270.11 ORX90445.1 - 0.0026 17.5 0.2 0.0052 16.5 0.2 1.6 1 1 1 2 2 2 1 M protein trans-acting positive regulator (MGA) PRD domain PsaL PF02605.15 ORX90445.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Syndecan PF01034.20 ORX90445.1 - 0.16 11.9 1.1 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 Syndecan domain zf-C2H2 PF00096.26 ORX90446.1 - 1.5e-16 59.8 19.3 5.3e-07 29.7 2.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX90446.1 - 2.2e-14 53.1 5.2 6.1e-09 35.9 0.4 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX90446.1 - 5.8e-12 45.4 17.7 0.00041 20.9 2.8 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX90446.1 - 5.5e-09 36.1 3.9 0.006 16.8 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX90446.1 - 1.6e-07 31.2 12.6 0.0002 21.3 0.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORX90446.1 - 1.7e-06 28.2 7.6 0.039 14.4 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX90446.1 - 0.0016 18.7 5.8 0.013 15.8 5.8 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 ORX90446.1 - 0.0044 16.8 0.8 0.0044 16.8 0.8 3.3 5 0 0 5 5 4 1 C2H2-type zinc-finger domain zf_ZIC PF18366.1 ORX90446.1 - 0.0057 16.7 0.6 0.75 10.0 0.0 2.4 2 0 0 2 2 2 1 Zic proteins zinc finger domain FOXP-CC PF16159.5 ORX90446.1 - 0.0074 16.9 0.6 0.017 15.8 0.1 1.7 1 1 1 2 2 2 1 FOXP coiled-coil domain C1_4 PF07975.12 ORX90446.1 - 0.013 15.8 5.9 0.018 15.2 1.1 2.1 1 1 2 3 3 3 0 TFIIH C1-like domain zf-MYST PF17772.1 ORX90446.1 - 0.015 14.9 1.0 2 8.1 0.2 2.4 2 1 0 2 2 2 0 MYST family zinc finger domain zf-AN1 PF01428.16 ORX90446.1 - 0.034 14.3 9.4 0.29 11.3 3.9 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger C5HCH PF17982.1 ORX90446.1 - 0.045 13.9 6.3 0.045 13.9 6.3 2.3 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-TRAF PF02176.18 ORX90446.1 - 0.2 12.4 6.4 0.35 11.6 3.6 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-LYAR PF08790.11 ORX90446.1 - 0.59 10.1 4.7 23 5.0 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORX90446.1 - 0.77 10.1 4.8 16 5.9 0.3 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Glyoxal_oxid_N PF07250.11 ORX90448.1 - 8.5e-54 182.3 0.1 5.8e-51 173.0 0.1 3.7 2 2 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORX90448.1 - 1e-30 105.8 1.0 8.4e-30 102.9 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 ORX90448.1 - 0.00079 19.3 0.0 10 6.3 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 ORX90448.1 - 0.001 19.0 0.5 3.7 7.6 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX90448.1 - 0.033 14.5 3.2 13 6.3 0.0 4.2 4 1 1 5 5 5 0 Kelch motif DUF5122 PF17164.4 ORX90448.1 - 0.095 13.0 0.2 7.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Velvet PF11754.8 ORX90449.1 - 6.4e-66 222.8 0.9 2.6e-37 129.1 0.2 2.0 1 1 1 2 2 2 2 Velvet factor NmrA PF05368.13 ORX90450.1 - 7.7e-13 48.5 0.0 2.8e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 ORX90450.1 - 4.9e-12 46.1 0.1 3.3e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORX90450.1 - 5.5e-08 32.2 1.0 6.6e-08 31.9 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX90450.1 - 0.0011 18.4 0.0 0.0076 15.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORX90450.1 - 0.0028 17.9 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 ORX90450.1 - 0.018 14.2 0.1 0.042 13.0 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 ORX90450.1 - 0.069 12.3 2.0 0.54 9.3 0.1 2.7 2 1 0 3 3 3 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 ORX90450.1 - 0.077 13.4 0.1 0.21 12.0 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pinin_SDK_memA PF04696.13 ORX90452.1 - 7.5e-28 97.2 21.5 7.5e-28 97.2 21.5 3.4 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region WD40 PF00400.32 ORX90453.1 - 1.1e-47 158.9 21.9 1.3e-07 32.2 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90453.1 - 8e-14 51.7 2.4 0.046 14.0 0.0 6.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX90453.1 - 0.00034 19.4 6.2 0.086 11.5 0.8 4.2 3 1 0 3 3 3 2 Nucleoporin Nup120/160 CLTH PF10607.9 ORX90453.1 - 0.0012 18.7 0.8 0.0022 17.9 0.8 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_like PF17005.5 ORX90453.1 - 0.0017 17.8 2.5 0.56 9.5 0.1 4.1 3 2 1 4 4 4 1 WD40-like domain LisH_TPL PF17814.1 ORX90453.1 - 0.0022 17.6 0.0 0.007 16.0 0.0 1.9 1 0 0 1 1 1 1 LisH-like dimerisation domain PYC_OADA PF02436.18 ORX90453.1 - 0.028 14.2 0.3 0.05 13.4 0.3 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain PQQ PF01011.21 ORX90453.1 - 0.11 12.5 0.9 1.2 9.2 0.2 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat BBS2_Mid PF14783.6 ORX90453.1 - 0.25 11.4 1.4 5.3 7.1 0.0 3.7 4 2 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region B_lectin PF01453.24 ORX90453.1 - 0.31 11.6 2.1 0.52 10.9 0.2 2.3 2 0 0 2 2 2 0 D-mannose binding lectin PIGA PF08288.12 ORX90454.1 - 1.2e-43 147.6 1.5 2.8e-43 146.4 1.5 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 ORX90454.1 - 5.1e-26 91.7 1.1 8e-26 91.0 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ORX90454.1 - 7.7e-25 87.4 0.0 1.3e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX90454.1 - 2.8e-20 73.1 0.1 5.9e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORX90454.1 - 3.6e-09 37.3 0.0 5.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ORX90454.1 - 4.1e-07 30.1 0.2 7.1e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Mucin PF01456.17 ORX90455.1 - 0.0021 18.1 14.7 0.0023 18.0 14.7 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Pro-rich PF15240.6 ORX90455.1 - 0.0036 17.6 2.0 0.0049 17.2 2.0 1.3 1 0 0 1 1 1 1 Proline-rich SpoIIIAH PF12685.7 ORX90455.1 - 0.01 15.7 5.4 0.012 15.4 5.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein MCM_bind PF09739.9 ORX90455.1 - 0.02 13.4 2.4 0.022 13.2 2.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Conotoxin PF02950.17 ORX90455.1 - 0.02 15.9 0.0 0.032 15.2 0.0 1.5 1 1 0 1 1 1 0 Conotoxin Zip PF02535.22 ORX90455.1 - 0.061 12.5 0.2 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 ORX90455.1 - 0.14 12.3 1.0 0.17 12.1 1.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 ORX90455.1 - 0.17 10.6 0.7 0.19 10.5 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 ORX90455.1 - 0.32 10.3 5.4 0.39 10.0 5.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 ORX90455.1 - 0.33 9.7 6.7 0.34 9.7 6.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ctr PF04145.15 ORX90455.1 - 0.37 11.4 1.7 0.67 10.6 1.6 1.4 1 1 0 1 1 1 0 Ctr copper transporter family Menin PF05053.13 ORX90455.1 - 0.99 7.7 7.9 1.2 7.5 7.9 1.1 1 0 0 1 1 1 0 Menin DUF4834 PF16118.5 ORX90455.1 - 1 10.4 6.7 3.6 8.6 6.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ASD2 PF08687.11 ORX90455.1 - 1.3 8.5 2.9 1.6 8.2 2.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF3827 PF12877.7 ORX90455.1 - 1.5 7.1 12.4 1.8 6.8 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Apt1 PF10351.9 ORX90455.1 - 1.6 7.5 17.2 1.8 7.4 17.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 ORX90455.1 - 1.8 7.2 11.7 1.9 7.1 11.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 ORX90455.1 - 2 6.5 9.3 2.1 6.3 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 ORX90455.1 - 2.4 6.8 9.5 3 6.5 9.5 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 ORX90455.1 - 2.6 7.1 23.2 3 6.9 23.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein PP_M1 PF03012.14 ORX90455.1 - 3.7 7.0 14.1 5 6.6 14.1 1.1 1 0 0 1 1 1 0 Phosphoprotein Striatin PF08232.12 ORX90455.1 - 4.8 7.8 6.4 6.7 7.3 6.4 1.2 1 0 0 1 1 1 0 Striatin family DUF1180 PF06679.12 ORX90455.1 - 7 7.0 14.3 9.8 6.6 14.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) FSA_C PF10479.9 ORX90455.1 - 8.3 4.4 16.6 9.9 4.2 16.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sec10 PF07393.11 ORX90455.1 - 8.5 4.7 7.5 9.1 4.6 7.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 HATPase_c PF02518.26 ORX90457.1 - 1.5e-26 93.1 0.4 2.6e-26 92.3 0.4 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX90457.1 - 7.4e-25 87.3 0.1 1.4e-24 86.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORX90457.1 - 4.2e-18 65.2 0.1 1e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ORX90457.1 - 2e-05 24.9 0.0 9.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 ORX90457.1 - 3.8e-05 24.3 0.0 0.00011 22.9 0.0 1.8 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 ORX90457.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 ORX90457.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 GAF domain TUSC2 PF15000.6 ORX90457.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Thaumatin PF00314.17 ORX90458.1 - 2.8e-71 239.6 13.5 3.2e-71 239.4 13.5 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORX90458.1 - 0.049 12.9 0.3 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase GrpE PF01025.19 ORX90459.1 - 0.0075 15.9 5.8 0.013 15.2 5.8 1.4 1 0 0 1 1 1 1 GrpE SpoVIF PF14069.6 ORX90459.1 - 0.17 11.7 4.1 0.22 11.3 1.0 2.2 2 0 0 2 2 2 0 Stage VI sporulation protein F ZnuA PF01297.17 ORX90459.1 - 0.51 9.7 4.0 8.7 5.7 0.0 2.2 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Peptidase_M24 PF00557.24 ORX90461.1 - 6e-54 182.9 0.0 6.9e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4949 PF16307.5 ORX90461.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) NAD_Gly3P_dh_N PF01210.23 ORX90462.1 - 3.2e-51 173.4 0.1 4.8e-51 172.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORX90462.1 - 2.3e-46 157.6 0.2 3.8e-46 156.9 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus MIP PF00230.20 ORX90463.1 - 6.2e-31 107.9 10.2 7.9e-31 107.5 10.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein HisG PF01634.18 ORX90464.1 - 8.2e-53 178.6 1.2 1.2e-52 178.1 1.2 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ORX90464.1 - 3.2e-30 104.1 0.1 6.2e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 ORX90464.1 - 3.1e-05 24.0 0.2 4.6e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Ras PF00071.22 ORX90465.1 - 7.4e-41 139.5 0.0 8.8e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90465.1 - 2.9e-21 75.9 0.0 3.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90465.1 - 1.4e-09 37.6 0.0 1.6e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX90465.1 - 3.4e-05 23.9 0.0 4.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX90465.1 - 0.00011 21.8 0.1 0.0015 18.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORX90465.1 - 0.00074 19.0 0.1 0.0011 18.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORX90466.1 - 2e-49 167.3 0.0 2.3e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90466.1 - 1.5e-19 70.4 0.0 2.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90466.1 - 3e-08 33.3 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX90466.1 - 2.2e-06 27.4 0.3 2e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORX90466.1 - 8.6e-05 22.0 0.1 0.00016 21.2 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORX90466.1 - 0.00029 20.9 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX90466.1 - 0.00054 19.5 0.0 0.085 12.4 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX90466.1 - 0.0035 17.3 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Kinase-PPPase PF03618.14 ORX90466.1 - 0.029 14.2 0.0 0.09 12.5 0.0 1.7 1 1 1 2 2 2 0 Kinase/pyrophosphorylase Ribosomal_L27A PF00828.19 ORX90467.1 - 5.4e-23 82.1 0.2 7.3e-23 81.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Cnd1 PF12717.7 ORX90468.1 - 6.3e-55 185.6 8.1 9.6e-51 172.0 0.4 4.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 ORX90468.1 - 7.7e-37 126.7 2.1 7.7e-37 126.7 2.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 ORX90468.1 - 7.3e-12 45.5 0.0 0.00023 21.5 0.0 4.6 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 ORX90468.1 - 1e-08 34.7 4.2 0.016 15.4 0.0 6.0 7 0 0 7 7 6 2 HEAT repeat HEAT_EZ PF13513.6 ORX90468.1 - 1.8e-08 34.7 0.2 0.024 15.1 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 ORX90468.1 - 6.6e-06 26.3 0.1 0.11 12.7 0.0 3.5 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 ORX90468.1 - 0.00041 19.6 11.3 0.012 14.8 2.1 3.9 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.13 ORX90468.1 - 0.0095 15.4 0.8 0.033 13.7 0.2 2.4 2 1 0 2 2 2 1 Armadillo-like Tower PF09121.10 ORX90468.1 - 0.054 13.7 0.4 0.19 11.9 0.4 1.9 1 0 0 1 1 1 0 Tower Cohesin_HEAT PF12765.7 ORX90468.1 - 0.078 13.3 1.4 7.8 6.9 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 ORX90468.1 - 0.11 12.6 0.0 18 5.6 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 ORX90468.1 - 0.12 12.2 0.8 4 7.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) DDHD PF02862.17 ORX90468.1 - 2.1 8.4 13.8 8.3 6.5 0.2 3.9 4 0 0 4 4 4 0 DDHD domain SHMT PF00464.19 ORX90469.1 - 1.5e-183 609.9 0.0 1.8e-183 609.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 ORX90469.1 - 8.1e-08 31.9 0.1 4.9e-07 29.3 0.1 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORX90469.1 - 9.3e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.6 ORX90469.1 - 0.016 15.5 3.4 0.1 12.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) DegT_DnrJ_EryC1 PF01041.17 ORX90469.1 - 0.065 12.5 0.1 0.13 11.5 0.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy_2 PF13532.6 ORX90470.1 - 9.7e-26 91.2 0.0 3.6e-25 89.3 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCM1_C PF15717.5 ORX90470.1 - 0.0011 17.8 0.1 0.0014 17.4 0.1 1.1 1 0 0 1 1 1 1 Pericentriolar material 1 C terminus HLH PF00010.26 ORX90471.1 - 1.4e-08 34.5 3.4 2.2e-08 33.9 1.4 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain LtrA PF06772.11 ORX90472.1 - 2.9e-94 316.2 31.4 3.3e-94 316.0 31.4 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Pro_CA PF00484.19 ORX90473.1 - 1.3e-49 168.4 0.4 2.1e-49 167.8 0.4 1.3 1 0 0 1 1 1 1 Carbonic anhydrase RdRP PF05183.12 ORX90474.1 - 2.1e-157 525.3 0.0 2.9e-157 524.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase PET PF06297.14 ORX90474.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 PET Domain Sugar_tr PF00083.24 ORX90475.1 - 2e-103 346.7 30.4 2.4e-103 346.5 30.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX90475.1 - 7.4e-28 97.5 30.8 3.7e-27 95.2 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.6 ORX90475.1 - 0.047 13.2 2.0 0.12 11.9 2.0 1.7 1 0 0 1 1 1 0 Negative regulator of p53/TP53 UQ_con PF00179.26 ORX90476.1 - 4e-38 130.2 0.1 4.9e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX90476.1 - 0.037 14.3 0.1 0.1 12.9 0.0 1.7 1 1 1 2 2 2 0 RWD domain PhoLip_ATPase_C PF16212.5 ORX90477.1 - 3e-69 233.5 34.8 3e-69 233.5 34.8 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX90477.1 - 1e-23 82.8 2.6 1e-23 82.8 2.6 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORX90477.1 - 1e-11 44.7 0.0 9.3e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX90477.1 - 2.1e-09 38.0 0.0 0.00096 19.5 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX90477.1 - 1e-06 28.4 0.1 0.00023 20.8 0.0 2.8 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORX90477.1 - 0.00012 21.9 0.0 0.00044 20.1 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PH PF00169.29 ORX90478.1 - 0.0057 17.2 1.1 0.0095 16.4 0.4 1.8 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 ORX90478.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TetR_C_24 PF17932.1 ORX90478.1 - 0.13 12.6 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GYF PF02213.16 ORX90479.1 - 5.5e-10 38.8 1.3 1.2e-09 37.7 1.3 1.6 1 0 0 1 1 1 1 GYF domain TMCO5 PF14992.6 ORX90479.1 - 0.098 12.2 9.7 0.14 11.7 9.7 1.2 1 0 0 1 1 1 0 TMCO5 family IMP2_N PF18590.1 ORX90479.1 - 0.16 12.5 0.7 0.46 11.1 0.5 1.9 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) N-terminal domain PEX11 PF05648.14 ORX90479.1 - 6 6.3 7.1 0.42 10.0 1.0 1.8 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) tRNA_synt_1c_R2 PF04557.15 ORX90479.1 - 9 7.3 13.9 1.7 9.6 0.6 2.8 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Arrestin_C PF02752.22 ORX90480.1 - 4.8e-17 62.7 0.0 1.9e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90480.1 - 2.9e-09 37.2 0.1 1.6e-08 34.7 0.1 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX90480.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like RSN1_7TM PF02714.15 ORX90481.1 - 1.4e-67 227.9 29.7 1.8e-67 227.5 29.7 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX90481.1 - 1e-09 38.8 0.0 1.7e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Exo_endo_phos PF03372.23 ORX90482.1 - 4.7e-15 55.8 0.1 9.5e-15 54.7 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5326 PF17260.2 ORX90482.1 - 0.061 13.5 4.4 0.12 12.5 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) FSH1 PF03959.13 ORX90483.1 - 6.3e-58 195.9 0.0 7.1e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 ORX90483.1 - 0.048 13.2 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 PE-PPE domain BAAT_C PF08840.11 ORX90483.1 - 0.12 12.3 0.1 0.43 10.5 0.0 1.9 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal EF-hand_1 PF00036.32 ORX90484.1 - 6.7e-27 91.0 12.9 5.4e-08 31.8 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX90484.1 - 3.2e-23 82.0 5.9 6.4e-13 49.0 0.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX90484.1 - 8.8e-22 75.1 7.6 1.7e-05 24.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORX90484.1 - 2.4e-21 74.2 15.1 2.3e-07 30.0 0.6 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORX90484.1 - 1.2e-13 50.7 14.0 3.3e-05 23.6 0.5 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX90484.1 - 1.2e-06 28.8 0.0 0.0052 17.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORX90484.1 - 1.8e-05 24.7 5.2 0.097 12.6 0.4 3.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORX90484.1 - 0.0014 19.0 0.2 0.91 9.9 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain DUF5380 PF17351.2 ORX90484.1 - 0.051 13.4 0.2 0.58 10.1 0.0 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5380) Sigma54_CBD PF04963.13 ORX90484.1 - 0.11 12.4 0.1 1.5 8.6 0.0 2.2 1 1 0 2 2 2 0 Sigma-54 factor, core binding domain Dockerin_1 PF00404.18 ORX90484.1 - 0.15 12.3 4.7 3.9 7.8 0.4 2.9 1 1 2 3 3 3 0 Dockerin type I domain MCD PF05292.11 ORX90485.1 - 7.1e-97 324.0 0.0 9e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 ORX90485.1 - 1.6e-08 34.6 0.8 2.8e-08 33.8 0.3 1.6 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain MFS_1 PF07690.16 ORX90486.1 - 1.8e-26 92.9 64.4 9.8e-18 64.2 39.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX90486.1 - 0.0012 17.8 31.7 0.084 11.7 2.1 3.3 2 2 1 3 3 3 3 MFS_1 like family Pam17 PF08566.10 ORX90486.1 - 0.24 11.2 1.5 0.41 10.5 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 LRR_8 PF13855.6 ORX90487.1 - 3e-17 62.1 25.8 6.7e-09 35.4 2.0 3.6 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORX90487.1 - 1.3e-13 50.9 35.9 5.5e-06 26.6 2.8 4.1 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX90487.1 - 0.02 14.4 4.5 0.13 11.7 4.6 2.2 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 ORX90487.1 - 0.022 14.8 7.3 1.1 9.5 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 ORX90487.1 - 0.6 10.9 15.7 7.8 7.5 0.2 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_3 PF07725.12 ORX90487.1 - 1.9 8.5 6.0 12 6.0 0.5 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Arylsulfotrans PF05935.11 ORX90488.1 - 2.1e-25 89.5 0.1 2e-14 53.3 0.0 2.4 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 ORX90488.1 - 6.9e-21 74.9 0.0 1.3e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 ORX90488.1 - 5e-06 26.3 0.0 2.6e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 ORX90488.1 - 0.043 13.7 1.1 38 4.4 0.0 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat B_lectin PF01453.24 ORX90488.1 - 0.051 14.1 1.2 0.48 11.0 0.2 3.0 4 1 0 4 4 4 0 D-mannose binding lectin AOX PF01786.17 ORX90490.1 - 3.5e-85 285.0 0.4 4.7e-85 284.6 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase PAS PF00989.25 ORX90491.1 - 1.2e-12 47.8 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ORX90491.1 - 2.7e-12 46.8 0.0 4.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 ORX90491.1 - 6.1e-09 35.3 0.3 1.4e-08 34.2 0.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.7 ORX90491.1 - 8.4e-07 29.2 0.0 2.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 ORX90491.1 - 9.2e-07 29.0 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX90491.1 - 1.2e-05 25.5 0.0 1.9e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold Chitin_synth_2 PF03142.15 ORX90492.1 - 8.2e-281 932.2 0.1 1.2e-280 931.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX90492.1 - 2.9e-13 50.3 0.0 9e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX90492.1 - 8.4e-12 45.4 8.8 8.4e-12 45.4 8.8 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX90492.1 - 5.6e-05 22.7 0.0 0.01 15.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX90492.1 - 0.0046 16.8 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1981 PF09324.10 ORX90493.1 - 0.2 11.5 4.2 11 6.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Pkinase PF00069.25 ORX90494.1 - 5.3e-68 229.2 0.0 6.5e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90494.1 - 1.6e-28 99.7 0.0 2.5e-28 99.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX90494.1 - 3.4e-06 26.6 0.1 0.0002 20.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 ORX90494.1 - 0.0018 17.9 0.1 0.0037 16.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORX90494.1 - 0.0022 17.0 0.0 0.0049 15.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX90494.1 - 0.052 12.9 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm7 PF15585.6 ORX90494.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 7 APH PF01636.23 ORX90494.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family HABP4_PAI-RBP1 PF04774.15 ORX90495.1 - 0.00057 20.7 7.2 0.00057 20.7 7.2 4.4 2 2 2 4 4 4 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 ORX90495.1 - 0.03 15.2 0.2 0.03 15.2 0.2 3.2 3 0 0 3 3 3 0 Stm1 Ras PF00071.22 ORX90496.1 - 2e-53 180.3 0.0 2.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90496.1 - 2.6e-20 72.8 0.0 4.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90496.1 - 5.4e-09 35.8 0.0 7.2e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX90496.1 - 2.8e-06 26.9 0.0 3.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX90496.1 - 0.0035 16.9 0.0 0.0041 16.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORX90496.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORX90496.1 - 0.034 13.3 0.0 0.039 13.1 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 ORX90496.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RasGAP PF00616.19 ORX90498.1 - 2.9e-25 89.2 0.6 2.4e-15 56.8 0.4 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 ORX90498.1 - 1.5e-16 60.8 1.9 4e-07 30.5 0.0 3.5 4 0 0 4 4 4 2 PH domain C2 PF00168.30 ORX90498.1 - 3.7e-16 59.3 0.0 7.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain BAR_3 PF16746.5 ORX90498.1 - 5.9e-15 55.6 2.7 1.9e-14 54.0 2.7 1.8 1 1 0 1 1 1 1 BAR domain of APPL family PH_9 PF15410.6 ORX90498.1 - 1.1e-06 29.0 0.1 0.0046 17.3 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.6 ORX90498.1 - 0.028 14.7 0.1 0.074 13.3 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 ORX90498.1 - 0.029 14.8 3.3 0.67 10.4 0.4 3.5 3 0 0 3 3 3 0 Pleckstrin homology domain Ribosomal_L32e PF01655.18 ORX90499.1 - 1.1e-53 180.3 3.0 1.1e-53 180.3 3.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 Pkinase PF00069.25 ORX90500.1 - 4.5e-65 219.6 0.0 5.3e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90500.1 - 1.4e-42 145.8 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX90500.1 - 0.0029 16.4 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORX90500.1 - 0.011 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 ORX90500.1 - 0.047 13.0 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 ORX90500.1 - 0.067 12.1 0.0 0.12 11.2 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Peptidase_S10 PF00450.22 ORX90502.1 - 3e-130 435.4 1.4 3.7e-130 435.1 1.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.13 ORX90502.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold GTP_EFTU PF00009.27 ORX90503.1 - 4.9e-46 156.7 0.1 7.9e-46 156.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX90503.1 - 3.5e-15 56.3 0.0 1.2e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX90503.1 - 1.4e-10 41.4 0.7 2.7e-09 37.3 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX90503.1 - 2.5e-05 24.3 0.0 0.01 15.9 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORX90503.1 - 0.00016 21.5 0.3 0.00058 19.7 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ribosomal_S3_C PF00189.20 ORX90504.1 - 9.6e-24 83.7 1.1 3.9e-23 81.8 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORX90504.1 - 1.3e-12 47.4 0.1 2.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORX90504.1 - 0.047 14.2 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 ORX90504.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus HLH PF00010.26 ORX90506.1 - 1.2e-16 60.3 3.9 2.8e-16 59.2 3.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Copper-fist PF00649.18 ORX90507.1 - 6.5e-23 80.0 1.9 6.5e-23 80.0 1.9 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain Pyr_redox_2 PF07992.14 ORX90509.1 - 9.8e-42 143.2 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX90509.1 - 8.7e-16 58.3 0.0 5.7e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 ORX90509.1 - 5.3e-12 44.4 3.9 1.5e-05 24.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORX90509.1 - 1.4e-11 43.3 2.8 2.8e-05 23.7 0.8 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORX90509.1 - 8.3e-11 40.9 3.1 1.6e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ORX90509.1 - 4.6e-09 36.6 10.2 2.2e-07 31.2 3.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX90509.1 - 5.5e-06 26.1 1.3 0.13 12.1 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 ORX90509.1 - 0.0069 15.7 2.0 0.59 9.3 0.6 2.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX90509.1 - 0.095 12.9 0.0 28 5.0 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_4C PF11975.8 ORX90509.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Cyclin_N PF00134.23 ORX90510.1 - 1.7e-17 63.3 0.1 2.5e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORX90510.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Aa_trans PF01490.18 ORX90511.1 - 4.3e-74 249.7 37.0 5.2e-74 249.4 37.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1418 PF07214.12 ORX90511.1 - 6 6.8 10.0 1.6 8.7 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Aldo_ket_red PF00248.21 ORX90512.1 - 3.5e-62 210.3 0.0 4.2e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cyclin_N PF00134.23 ORX90513.1 - 5e-45 152.4 3.5 5e-44 149.1 1.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX90513.1 - 1.8e-25 89.3 0.4 4.5e-25 88.0 0.2 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Exo70 PF03081.15 ORX90514.1 - 8.7e-92 308.1 11.1 8.7e-92 308.1 11.1 2.1 2 1 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 ORX90514.1 - 0.0016 18.3 10.1 0.016 15.1 2.6 4.1 3 1 1 4 4 4 1 Sec34-like family DUF3603 PF12227.8 ORX90514.1 - 0.0054 16.1 0.9 0.014 14.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3603) Dynactin_p22 PF07426.11 ORX90514.1 - 0.043 13.7 10.8 1.8 8.4 0.8 4.1 4 0 0 4 4 4 0 Dynactin subunit p22 Arg_decarb_HB PF17810.1 ORX90514.1 - 0.11 12.8 0.5 24 5.3 0.0 3.5 3 0 0 3 3 3 0 Arginine decarboxylase helical bundle domain RNase_P_pop3 PF08228.11 ORX90515.1 - 0.017 15.2 0.1 0.019 15.0 0.1 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Glutaredoxin PF00462.24 ORX90516.1 - 5e-18 65.1 0.0 8.6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin FYRN PF05964.14 ORX90517.1 - 1.5e-17 63.2 0.1 3.1e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORX90517.1 - 1.3e-15 57.3 0.0 3.8e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus Ino80_Iec3 PF14612.6 ORX90517.1 - 1.5e-05 25.8 6.0 2.4e-05 25.1 6.0 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling YqfQ PF14181.6 ORX90517.1 - 4 7.6 8.1 10 6.3 8.1 1.6 1 0 0 1 1 1 0 YqfQ-like protein RNA_lig_T4_1 PF09511.10 ORX90518.1 - 3e-75 252.9 0.3 4.4e-75 252.3 0.3 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 ORX90518.1 - 1.5e-26 93.5 0.0 2.8e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 ORX90518.1 - 2.3e-22 79.7 0.2 5.5e-21 75.2 0.2 2.2 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 ORX90518.1 - 0.022 15.3 0.0 0.15 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORX90518.1 - 0.037 14.0 0.1 0.095 12.6 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ORC3_N PF07034.11 ORX90519.1 - 6.9e-21 74.7 0.1 1e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ORX90519.1 - 2.9e-15 56.6 0.6 1.8e-10 41.0 0.2 2.7 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal Brr6_like_C_C PF10104.9 ORX90521.1 - 8e-50 168.1 0.5 1e-49 167.7 0.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Babuvirus_MP PF07234.11 ORX90521.1 - 9.1 6.5 6.0 0.45 10.7 0.3 1.7 2 0 0 2 2 2 0 Movement and RNA silencing protein Homeodomain PF00046.29 ORX90523.1 - 1.9e-16 59.6 4.0 2.1e-16 59.5 4.0 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX90523.1 - 0.0021 17.9 2.8 0.0035 17.2 2.8 1.7 1 1 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX90523.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_11 PF08279.12 ORX90523.1 - 0.011 15.7 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 ORX90523.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Sigma_reg_N PF13800.6 ORX90524.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.7 1 1 1 2 2 2 0 Sigma factor regulator N-terminal LEA_2 PF03168.13 ORX90525.1 - 0.0003 21.3 0.0 0.00044 20.7 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein Rhodanese PF00581.20 ORX90526.1 - 5e-14 52.7 0.0 6.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase PF00102.27 ORX90527.1 - 2.6e-73 246.5 0.0 3.5e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORX90527.1 - 1.4e-08 35.2 0.0 8.9e-08 32.6 0.0 2.3 3 0 0 3 3 3 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 ORX90527.1 - 0.0032 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORX90527.1 - 0.004 17.0 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Bac_DnaA PF00308.18 ORX90527.1 - 0.053 13.3 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein DEAD PF00270.29 ORX90528.1 - 2.6e-44 151.1 0.1 2.2e-43 148.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90528.1 - 7.7e-29 100.3 0.0 1.4e-27 96.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 ORX90528.1 - 0.002 18.1 2.3 0.002 18.1 2.3 1.9 2 0 0 2 2 2 1 Zinc knuckle ResIII PF04851.15 ORX90528.1 - 0.0021 18.1 0.0 0.0081 16.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC_4 PF14392.6 ORX90528.1 - 0.42 10.4 2.8 0.27 11.0 0.8 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 ORX90528.1 - 2.1 8.2 6.8 0.2 11.5 1.6 2.0 2 0 0 2 2 2 0 Zinc knuckle CUE PF02845.16 ORX90529.1 - 2.5e-05 23.9 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 ORX90529.1 - 0.025 14.4 0.0 0.083 12.7 0.0 1.9 1 0 0 1 1 1 0 UBA-like domain Pacs-1 PF10254.9 ORX90531.1 - 0.0012 17.8 5.3 0.0015 17.6 5.3 1.0 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein Baculo_PEP_C PF04513.12 ORX90531.1 - 0.003 17.6 2.6 0.0046 17.0 2.6 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med11 PF10280.9 ORX90531.1 - 0.019 15.4 1.4 0.025 15.0 1.4 1.3 1 0 0 1 1 1 0 Mediator complex protein Apolipoprotein PF01442.18 ORX90531.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PMC2NT PF08066.12 ORX90531.1 - 0.37 11.5 2.7 1.8 9.3 2.7 2.1 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Adeno_PV PF03910.13 ORX90531.1 - 5.5 5.6 8.9 7.3 5.2 8.9 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV Mating_N PF12731.7 ORX90531.1 - 7.4 6.7 10.0 8.6 6.5 2.2 2.2 1 1 1 2 2 2 0 Mating-type protein beta 1 CoA_transf_3 PF02515.17 ORX90532.1 - 1.9e-123 412.3 0.0 2.1e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF202 PF02656.15 ORX90533.1 - 8e-14 51.8 0.0 3.1e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MARVEL PF01284.23 ORX90533.1 - 0.47 10.5 3.9 3.5 7.6 3.9 2.1 1 1 0 1 1 1 0 Membrane-associating domain 6PF2K PF01591.18 ORX90534.1 - 3.2e-77 258.8 0.9 4.4e-77 258.4 0.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORX90534.1 - 2.5e-38 131.8 0.0 4.7e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORX90534.1 - 1e-05 25.8 0.3 2.9e-05 24.3 0.3 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORX90534.1 - 0.00033 20.2 0.1 0.00072 19.1 0.1 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 HMG_CoA_synt_C PF08540.10 ORX90535.1 - 6.3e-104 347.5 3.5 8.4e-104 347.1 3.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ORX90535.1 - 6e-95 316.0 0.3 9.1e-95 315.4 0.3 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 ORX90535.1 - 0.0048 16.7 0.3 0.02 14.7 0.1 2.1 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 ORX90535.1 - 0.018 15.2 0.0 2 8.6 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3641 PF12345.8 ORX90535.1 - 0.019 15.0 0.1 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Dak2 PF02734.17 ORX90535.1 - 0.086 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 DAK2 domain Amino_oxidase PF01593.24 ORX90537.1 - 1.2e-52 179.8 0.0 2.1e-52 178.9 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORX90537.1 - 2e-09 37.5 0.2 7e-09 35.8 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX90537.1 - 9e-08 31.6 1.9 1.3e-07 31.0 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORX90537.1 - 2.9e-06 26.6 1.1 0.00095 18.3 0.6 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORX90537.1 - 2e-05 23.8 0.1 0.016 14.3 0.6 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 ORX90537.1 - 6.7e-05 22.6 0.0 0.00028 20.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORX90537.1 - 0.00015 21.3 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX90537.1 - 0.00022 20.6 0.2 0.0027 17.0 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX90537.1 - 0.00043 19.1 1.6 0.00098 17.9 1.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ORX90537.1 - 0.0013 18.0 0.6 0.0024 17.2 0.6 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ORX90537.1 - 0.0021 17.3 2.0 0.036 13.3 0.9 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORX90537.1 - 0.014 14.7 0.8 0.025 13.9 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ORX90537.1 - 0.05 14.2 0.4 0.18 12.4 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX90537.1 - 0.11 12.5 0.5 11 6.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding CBAH PF02275.18 ORX90538.1 - 0.0079 15.9 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Helicase_C PF00271.31 ORX90540.1 - 2.5e-05 24.6 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain C_Hendra PF16821.5 ORX90541.1 - 0.031 14.1 0.2 0.031 14.1 0.2 2.3 3 0 0 3 3 3 0 C protein from hendra and measles viruses GPI-anchored PF10342.9 ORX90542.1 - 2.3e-05 25.1 0.4 0.0001 23.0 0.4 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TLD PF07534.16 ORX90543.1 - 3.5e-38 131.0 0.0 4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 TLD zf-C2H2 PF00096.26 ORX90544.1 - 2.4e-09 37.1 17.6 0.00024 21.4 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90544.1 - 3.6e-06 27.4 15.1 0.0054 17.5 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX90544.1 - 8.7e-06 25.9 13.7 0.00022 21.5 1.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX90544.1 - 0.0075 16.2 10.6 0.017 15.1 4.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX90544.1 - 0.0086 16.3 2.9 0.17 12.2 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX90544.1 - 0.046 14.1 5.7 0.05 14.0 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Vps39_2 PF10367.9 ORX90544.1 - 0.051 14.0 0.1 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Med25_VWA PF11265.8 ORX90545.1 - 1.1e-24 87.4 0.0 2.1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A HSBP1 PF06825.12 ORX90546.1 - 5.4e-10 39.0 3.9 1e-09 38.1 3.9 1.6 1 1 0 1 1 1 1 Heat shock factor binding protein 1 NPV_P10 PF05531.12 ORX90546.1 - 0.0031 18.0 1.4 0.023 15.2 1.4 2.0 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein NleF_casp_inhib PF16809.5 ORX90546.1 - 0.0065 16.4 0.3 0.0076 16.2 0.3 1.1 1 0 0 1 1 1 1 NleF caspase inhibitor FliD_C PF07195.12 ORX90546.1 - 0.012 15.1 0.6 0.013 15.0 0.6 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus SF-assemblin PF06705.11 ORX90546.1 - 0.015 14.6 0.5 0.017 14.5 0.5 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin HsbA PF12296.8 ORX90546.1 - 0.017 15.5 0.4 0.7 10.3 0.1 2.1 1 1 1 2 2 2 0 Hydrophobic surface binding protein A DUF4094 PF13334.6 ORX90546.1 - 0.026 15.0 0.4 0.035 14.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF1515 PF07439.11 ORX90546.1 - 0.041 13.9 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) YojJ PF10372.9 ORX90546.1 - 0.044 13.9 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus BLOC1_2 PF10046.9 ORX90546.1 - 0.052 13.9 0.8 0.078 13.3 0.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 ORX90546.1 - 0.052 13.6 0.2 0.059 13.4 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CagA PF03507.13 ORX90546.1 - 0.054 13.4 0.1 0.054 13.4 0.1 1.1 1 0 0 1 1 1 0 CagA exotoxin DUF1664 PF07889.12 ORX90546.1 - 0.059 13.4 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V-SNARE PF05008.15 ORX90546.1 - 0.063 13.7 0.3 0.39 11.1 0.2 1.9 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.11 ORX90546.1 - 0.068 13.7 0.4 0.078 13.5 0.4 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal MtrB PF05440.12 ORX90546.1 - 0.12 12.8 0.4 0.32 11.4 0.1 1.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B LPP PF04728.13 ORX90546.1 - 0.16 12.3 1.7 1.3 9.5 0.2 2.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper FAM76 PF16046.5 ORX90546.1 - 0.18 11.1 0.2 0.19 11.1 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein Ribosomal_S17 PF00366.20 ORX90547.1 - 1.3e-26 92.5 2.6 1.5e-26 92.3 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 P19Arf_N PF07392.12 ORX90547.1 - 0.32 11.5 0.1 0.32 11.5 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus zf-C2H2 PF00096.26 ORX90548.1 - 1.9e-07 31.1 16.6 0.00014 22.1 1.2 3.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX90548.1 - 1.3e-06 28.6 16.0 0.00012 22.4 1.7 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX90548.1 - 0.00015 21.7 8.5 0.0027 17.7 3.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORX90548.1 - 0.00041 21.0 22.0 0.0027 18.4 0.6 3.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 ORX90548.1 - 0.0097 16.3 0.5 0.0097 16.3 0.5 2.3 2 1 0 2 2 2 1 Zinc-finger of C2H2 type Vps39_2 PF10367.9 ORX90548.1 - 0.034 14.6 0.1 0.065 13.7 0.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C2H2 PF00096.26 ORX90549.1 - 7.7e-11 41.8 10.2 3.4e-07 30.3 3.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90549.1 - 6e-09 36.0 8.3 0.00015 22.3 3.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX90549.1 - 1.4e-07 31.6 9.2 0.0011 19.3 0.2 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX90549.1 - 6.3e-07 29.2 4.2 0.00011 22.2 0.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX90549.1 - 0.00016 22.0 0.5 0.00016 22.0 0.5 2.8 2 1 1 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX90549.1 - 0.00074 19.7 0.4 0.00074 19.7 0.4 2.2 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORX90549.1 - 0.0037 17.0 3.6 0.41 10.4 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain Vps39_2 PF10367.9 ORX90549.1 - 0.062 13.8 0.1 0.092 13.2 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_2 PF12756.7 ORX90549.1 - 0.08 13.3 1.3 0.081 13.3 0.3 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 ORX90549.1 - 0.15 12.0 3.2 0.22 11.5 1.4 2.0 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Arrestin_C PF02752.22 ORX90550.1 - 1.2e-14 54.9 0.8 2.3e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90550.1 - 2.7e-10 40.5 0.0 2.9e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX90550.1 - 0.0017 17.6 0.0 0.53 9.4 0.0 2.8 2 1 0 3 3 3 2 Rgp1 LDB19 PF13002.7 ORX90550.1 - 0.055 13.2 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like Cellulase PF00150.18 ORX90551.1 - 1.3e-07 31.4 0.9 1.8e-07 30.9 0.1 1.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) LRR_4 PF12799.7 ORX90552.1 - 0.007 16.8 16.7 0.046 14.2 1.5 4.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX90552.1 - 0.59 9.9 10.3 1.4 8.8 0.6 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 ORX90552.1 - 1.3 9.3 9.8 5.8 7.2 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich repeat bZIP_2 PF07716.15 ORX90553.1 - 1.2e-07 31.7 15.0 2.2e-07 30.9 15.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX90553.1 - 1.1e-06 28.6 13.3 1.9e-06 27.9 13.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX90553.1 - 0.00036 21.0 10.0 0.00069 20.1 10.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor TPR_1 PF00515.28 ORX90554.1 - 3.8e-50 165.8 16.3 4.6e-07 29.4 0.0 10.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORX90554.1 - 2.1e-42 139.8 17.6 6.9e-06 25.8 0.0 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 ORX90554.1 - 8.2e-38 127.8 15.7 1.9e-09 37.0 1.8 8.7 6 3 2 8 8 8 6 TPR repeat TPR_17 PF13431.6 ORX90554.1 - 1.6e-34 115.8 7.4 5.2e-07 29.6 0.1 9.6 9 1 0 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORX90554.1 - 1.3e-30 103.0 16.7 6e-05 22.9 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORX90554.1 - 9.7e-25 87.0 1.0 1e-07 32.5 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX90554.1 - 4e-24 84.9 8.4 1.7e-06 28.5 0.0 6.3 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX90554.1 - 3.1e-22 77.3 0.2 0.077 13.9 0.0 9.5 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORX90554.1 - 8.4e-18 64.4 13.4 0.012 15.9 0.1 8.1 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 ORX90554.1 - 7.9e-15 53.7 3.1 0.21 11.7 0.0 8.6 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORX90554.1 - 1.8e-11 44.0 0.1 0.13 12.4 0.0 6.2 4 2 4 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX90554.1 - 8.8e-11 41.9 16.2 0.0043 17.2 0.1 5.5 3 2 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORX90554.1 - 3.1e-09 36.4 3.1 0.28 11.1 0.0 7.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX90554.1 - 1.7e-07 31.4 13.7 1.7 9.5 0.0 9.2 10 1 0 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORX90554.1 - 5.3e-06 26.7 2.5 1.1 9.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORX90554.1 - 1.2e-05 24.6 7.2 0.28 10.6 0.0 6.7 6 1 0 6 6 6 1 SHNi-TPR TPR_MalT PF17874.1 ORX90554.1 - 1.4e-05 24.7 0.2 0.011 15.1 0.4 3.2 3 1 1 4 4 4 1 MalT-like TPR region NARP1 PF12569.8 ORX90554.1 - 2.2e-05 23.6 0.3 0.002 17.1 0.0 4.3 2 2 2 4 4 4 2 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 ORX90554.1 - 0.0013 18.2 1.1 0.0056 16.1 0.0 2.5 2 1 0 2 2 2 1 Coatomer epsilon subunit MIT PF04212.18 ORX90554.1 - 0.0014 18.7 18.0 0.89 9.7 0.4 6.9 7 1 1 8 8 8 2 MIT (microtubule interacting and transport) domain YjcZ PF13990.6 ORX90554.1 - 0.011 15.1 0.2 0.024 14.0 0.2 1.5 1 0 0 1 1 1 0 YjcZ-like protein TPR_3 PF07720.12 ORX90554.1 - 0.08 13.0 8.2 4 7.5 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP19 PF11022.8 ORX90554.1 - 0.11 12.9 0.9 0.31 11.4 0.1 2.3 3 0 0 3 3 1 0 ATP synthase subunit K DUF3856 PF12968.7 ORX90554.1 - 1.3 9.0 12.9 23 5.0 0.1 5.8 5 2 1 6 6 6 0 Domain of Unknown Function (DUF3856) Ribosomal_L19e PF01280.20 ORX90557.1 - 8.5e-65 217.2 10.4 8.5e-65 217.2 10.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L19e bZIP_1 PF00170.21 ORX90558.1 - 4.9e-11 42.6 12.9 9.2e-11 41.7 12.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX90558.1 - 0.04 14.0 16.9 0.28 11.3 16.9 2.1 1 1 0 1 1 1 0 Basic region leucine zipper SHE3 PF17078.5 ORX90558.1 - 0.14 11.8 4.0 0.21 11.3 4.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 AAA_17 PF13207.6 ORX90558.1 - 0.16 12.4 0.2 0.26 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain bZIP_Maf PF03131.17 ORX90558.1 - 0.16 12.5 8.3 0.31 11.6 8.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 ORX90558.1 - 0.31 11.7 1.7 0.6 10.8 1.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ADIP PF11559.8 ORX90558.1 - 0.34 11.0 6.9 0.54 10.3 6.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LIAS_N PF16881.5 ORX90559.1 - 2.6e-25 88.9 0.1 6e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ORX90559.1 - 1.5e-12 48.2 0.1 6.1e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily HLH PF00010.26 ORX90560.1 - 1.6e-11 44.0 0.4 1.6e-11 44.0 0.4 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DASH_Spc19 PF08287.11 ORX90560.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.4 2 0 0 2 2 2 0 Spc19 MFS_1 PF07690.16 ORX90561.1 - 2.7e-53 181.1 20.1 2.7e-53 181.1 20.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX90561.1 - 1.8e-08 33.7 10.5 1.8e-08 33.7 10.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter DEAD PF00270.29 ORX90563.1 - 2.2e-33 115.5 0.1 3.6e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90563.1 - 2.1e-25 89.2 0.0 4.5e-24 84.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90563.1 - 2.5e-06 27.6 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORX90563.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 ORX90563.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 ORX90563.1 - 0.0044 17.4 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain eIF-5_eIF-2B PF01873.17 ORX90564.1 - 4.5e-43 145.8 0.2 8.5e-43 145.0 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORX90564.1 - 0.01 15.3 0.2 0.018 14.6 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 ORX90564.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) ABC_membrane_2 PF06472.15 ORX90565.1 - 2.3e-101 338.8 1.3 3.1e-101 338.3 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORX90565.1 - 1.5e-16 61.1 0.0 3.8e-16 59.9 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_23 PF13476.6 ORX90565.1 - 0.00063 20.3 0.3 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORX90565.1 - 0.0019 18.1 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 ORX90565.1 - 0.0035 17.1 0.0 0.0096 15.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ORX90565.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ORX90565.1 - 0.025 14.9 0.0 0.093 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 ORX90565.1 - 0.054 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ORX90565.1 - 0.058 13.8 0.2 0.17 12.3 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 ORX90565.1 - 0.078 12.4 0.1 4.2 6.7 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AnfO_nitrog PF09582.10 ORX90565.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) AAA_18 PF13238.6 ORX90565.1 - 0.12 12.9 0.0 0.34 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORX90565.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4763 PF15960.5 ORX90565.1 - 0.14 11.4 0.3 0.25 10.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF3584 PF12128.8 ORX90565.1 - 0.39 8.2 1.3 0.55 7.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) C12orf66_like PF09404.10 ORX90566.1 - 4.1e-45 154.4 3.3 3.7e-23 82.1 0.2 2.3 2 1 0 2 2 2 2 KICSTOR complex C12orf66 like Spc24 PF08286.11 ORX90567.1 - 1.6e-22 79.7 2.5 1.6e-22 79.7 2.5 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.9 ORX90567.1 - 0.035 14.1 14.8 0.061 13.3 14.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 ORX90567.1 - 0.064 13.2 12.7 0.16 11.9 12.2 1.9 1 1 0 1 1 1 0 Prefoldin subunit Exonuc_VII_L PF02601.15 ORX90567.1 - 0.21 11.1 2.6 0.21 11.1 2.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4600 PF15372.6 ORX90567.1 - 0.35 11.3 11.1 3.6 8.0 1.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) BST2 PF16716.5 ORX90567.1 - 0.43 11.2 13.4 0.13 12.9 4.9 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FapA PF03961.13 ORX90567.1 - 0.6 8.7 4.7 0.73 8.4 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 ORX90567.1 - 0.66 10.4 5.6 0.65 10.4 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 ORX90567.1 - 0.79 10.3 13.8 2.1 8.9 13.8 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 ORX90567.1 - 0.86 9.8 7.5 2 8.6 7.5 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DMPK_coil PF08826.10 ORX90567.1 - 2.2 8.4 10.2 0.12 12.5 3.4 2.3 2 1 1 3 3 3 0 DMPK coiled coil domain like DivIC PF04977.15 ORX90567.1 - 6.7 6.6 8.0 3.6 7.4 1.0 2.4 1 1 1 2 2 2 0 Septum formation initiator DEAD PF00270.29 ORX90568.1 - 6.1e-29 101.0 0.2 1.1e-28 100.2 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90568.1 - 7.4e-12 45.6 0.0 2.1e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90568.1 - 3e-05 24.1 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORX90568.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF4449 PF14613.6 ORX90569.1 - 5.8e-06 26.5 2.2 9.4e-06 25.8 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 ORX90569.1 - 0.0026 17.4 0.1 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain DUF4449 PF14613.6 ORX90570.1 - 0.034 14.3 0.9 0.034 14.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) FPP PF05911.11 ORX90570.1 - 0.094 10.9 4.8 0.15 10.2 0.4 2.3 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Cullin PF00888.22 ORX90571.1 - 0.036 12.7 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Cullin family O-FucT PF10250.9 ORX90575.1 - 2.1e-16 60.6 0.0 1.5e-14 54.5 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cyclin_N PF00134.23 ORX90575.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain O-FucT PF10250.9 ORX90576.1 - 1e-21 78.0 0.0 1.1e-20 74.7 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-C2H2 PF00096.26 ORX90577.1 - 2.7e-12 46.4 12.8 2.1e-07 31.0 0.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90577.1 - 2e-06 28.2 10.2 0.00044 20.8 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX90577.1 - 3.5e-06 27.2 14.0 8.3e-06 26.0 3.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX90577.1 - 0.0001 22.2 0.8 0.0001 22.2 0.8 2.9 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORX90577.1 - 0.00016 21.9 1.3 0.15 12.2 0.3 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger FOXP-CC PF16159.5 ORX90577.1 - 0.00076 20.1 1.2 0.067 13.8 0.0 2.1 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX90577.1 - 0.0029 17.9 0.5 0.0093 16.2 0.5 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon CHORD PF04968.12 ORX90577.1 - 0.023 15.4 2.8 1.2 9.9 0.3 2.1 1 1 1 2 2 2 0 CHORD Ogr_Delta PF04606.12 ORX90577.1 - 0.027 14.4 0.1 4.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-met PF12874.7 ORX90577.1 - 0.039 14.3 2.0 3.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX90577.1 - 0.16 12.3 4.3 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CcmD PF04995.14 ORX90578.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MFS_1 PF07690.16 ORX90579.1 - 6.3e-13 48.4 28.7 1.1e-12 47.5 28.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90579.1 - 1.5e-09 37.7 5.6 1.5e-09 37.7 5.6 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 CYYR1 PF10873.8 ORX90579.1 - 1.6 9.2 3.5 23 5.4 0.0 2.5 1 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 MFS_1 PF07690.16 ORX90580.1 - 3.3e-13 49.3 26.6 5.6e-13 48.6 26.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90580.1 - 1.6e-09 37.7 5.5 1.6e-09 37.7 5.5 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 FAD_binding_4 PF01565.23 ORX90581.1 - 3.5e-26 91.6 0.9 5.9e-26 90.9 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX90581.1 - 5.6e-20 71.2 2.2 1.2e-19 70.1 2.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ORX90581.1 - 0.044 13.2 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Cu_amine_oxid PF01179.20 ORX90599.1 - 2.9e-160 533.7 0.9 3.5e-160 533.4 0.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORX90599.1 - 3.8e-13 49.7 0.0 9.3e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORX90599.1 - 9.5e-08 32.2 0.0 2.7e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain GDA1_CD39 PF01150.17 ORX90600.1 - 5.6e-109 364.6 0.1 6.6e-109 364.4 0.1 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 ORX90600.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Fer2_3 PF13085.6 ORX90601.1 - 2e-33 114.7 0.0 3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ORX90601.1 - 1.7e-09 38.1 6.8 1.7e-09 38.1 6.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORX90601.1 - 1e-06 29.1 8.0 1e-06 29.1 8.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORX90601.1 - 1.1e-06 28.7 3.3 1.1e-06 28.7 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ORX90601.1 - 0.0013 19.3 4.7 0.0013 19.3 4.7 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ORX90601.1 - 0.002 18.1 0.7 0.002 18.1 0.7 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 ORX90601.1 - 1.8 8.8 15.8 0.039 14.1 7.2 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain SMK-1 PF04802.15 ORX90602.1 - 0.016 15.1 1.0 0.031 14.1 0.4 1.8 2 0 0 2 2 2 0 Component of IIS longevity pathway SMK-1 Csm1_N PF18504.1 ORX90602.1 - 0.058 13.7 3.3 2.4 8.6 0.3 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain Herpes_UL6 PF01763.16 ORX90602.1 - 0.085 11.4 8.3 0.11 11.0 1.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like RRF_GI PF12614.8 ORX90602.1 - 0.087 13.0 0.6 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Ribosome recycling factor Lipid_bd PF12888.7 ORX90602.1 - 0.12 12.8 0.2 0.28 11.6 0.2 1.6 1 0 0 1 1 1 0 Lipid-binding putative hydrolase CSTF2_hinge PF14327.6 ORX90602.1 - 0.24 11.9 2.5 1.6 9.2 0.1 2.9 3 1 1 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 PMC2NT PF08066.12 ORX90602.1 - 0.58 10.9 4.7 0.61 10.8 0.3 2.8 2 1 1 3 3 3 0 PMC2NT (NUC016) domain AA_permease PF00324.21 ORX90603.1 - 1.7e-134 449.1 44.4 1.9e-134 448.9 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX90603.1 - 1.4e-43 149.3 47.0 2e-43 148.8 47.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 ORX90603.1 - 9.3 6.4 7.8 30 4.7 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function Ecl1 PF12855.7 ORX90604.1 - 9.5e-12 46.4 4.5 1.1e-11 46.2 4.5 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 ORX90604.1 - 0.042 13.8 0.4 0.066 13.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) C1_2 PF03107.16 ORX90604.1 - 0.06 13.7 4.4 0.06 13.7 4.4 1.9 2 0 0 2 2 2 0 C1 domain zf-MYND PF01753.18 ORX90604.1 - 0.29 11.3 4.1 0.48 10.5 4.1 1.3 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.9 ORX90604.1 - 1.4 9.1 7.4 88 3.3 7.4 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) SAM_1 PF00536.30 ORX90605.1 - 6.2e-12 45.8 0.1 1e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box PF00505.19 ORX90605.1 - 1.5e-11 44.6 2.3 3.2e-11 43.5 2.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX90605.1 - 1.1e-08 35.5 3.6 1.3e-08 35.3 2.1 1.9 1 1 1 2 2 2 1 HMG-box domain SAM_2 PF07647.17 ORX90605.1 - 4.3e-08 33.2 0.1 6.7e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORX90605.1 - 6.5e-05 22.9 0.0 0.00026 20.9 0.0 1.9 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) RE_NgoFVII PF09565.10 ORX90605.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Bestrophin PF01062.21 ORX90606.1 - 2.4e-47 161.8 0.1 2.8e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MS_channel PF00924.18 ORX90606.1 - 0.45 10.0 3.9 7.7 6.0 0.0 2.5 3 0 0 3 3 3 0 Mechanosensitive ion channel C2 PF00168.30 ORX90607.1 - 2.7e-24 85.4 0.1 9.1e-24 83.7 0.1 1.8 1 1 1 2 2 2 1 C2 domain Polysacc_deac_1 PF01522.21 ORX90608.1 - 1e-27 96.5 0.0 1.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX90608.1 - 8.4e-08 32.6 21.5 2e-07 31.3 21.5 1.7 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 ORX90608.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Beach PF02138.18 ORX90609.1 - 3.4e-127 423.5 1.1 1.8e-126 421.1 0.5 2.2 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 ORX90609.1 - 3.4e-17 62.5 0.9 2.4e-07 31.3 0.2 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PH_BEACH PF14844.6 ORX90609.1 - 4.9e-14 52.3 0.2 1.7e-13 50.5 0.2 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 ORX90609.1 - 6.2e-10 39.4 0.3 1.7e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.21 ORX90609.1 - 2.7e-08 33.8 15.5 5.3e-08 32.9 15.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF4704 PF15787.5 ORX90609.1 - 0.00011 21.5 0.3 0.00011 21.5 0.3 3.9 5 1 0 5 5 5 1 Domain of unknown function (DUF4704) Siva PF05458.12 ORX90609.1 - 6.3 6.4 12.0 13 5.4 12.0 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CK2S PF15011.6 ORX90610.1 - 0.19 11.6 2.0 1.5 8.7 0.3 2.4 2 1 0 3 3 3 0 Casein Kinase 2 substrate RTP1_C1 PF10363.9 ORX90611.1 - 1.1e-31 109.3 0.4 7.4e-31 106.6 0.1 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 ORX90611.1 - 4e-10 39.2 0.4 1.5e-09 37.4 0.4 2.1 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 ORX90611.1 - 0.00062 20.1 0.0 0.93 9.9 0.0 2.9 2 0 0 2 2 2 2 HEAT repeats Metallophos PF00149.28 ORX90613.1 - 9.5e-12 45.8 0.0 1.3e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX90613.1 - 4.7e-07 30.1 0.0 6.6e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 ORX90614.1 - 3.4e-05 23.6 0.1 0.0001 22.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX90614.1 - 0.00022 21.0 0.1 0.00055 19.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain PUF PF00806.19 ORX90615.1 - 6.6e-69 223.9 14.2 4.6e-09 35.5 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 ORX90615.1 - 0.018 14.9 2.1 7.8 6.3 0.0 4.5 5 0 0 5 5 5 0 Single Cache domain 2 CDC24 PF06395.11 ORX90617.1 - 1.6e-31 108.4 0.1 4.1e-31 107.1 0.1 1.7 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 ORX90617.1 - 2.2e-31 109.5 0.1 5.8e-31 108.1 0.1 1.8 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 ORX90617.1 - 4.1e-17 61.9 0.2 1.2e-16 60.4 0.2 1.8 1 0 0 1 1 1 1 PB1 domain PH_10 PF15411.6 ORX90617.1 - 5.7e-16 58.9 0.0 1.6e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORX90617.1 - 0.022 15.3 0.1 0.06 13.9 0.1 1.7 1 0 0 1 1 1 0 PH domain Chitin_synth_2 PF03142.15 ORX90618.1 - 3.3e-112 375.8 1.3 4.8e-112 375.3 1.3 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 ORX90618.1 - 6.3e-09 35.8 0.0 0.1 12.8 0.0 3.5 3 0 0 3 3 3 3 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 ORX90618.1 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORX90618.1 - 3e-07 30.5 3.9 7.4e-07 29.3 3.9 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX90618.1 - 0.00016 21.6 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORX90618.1 - 0.00061 19.7 0.0 0.0035 17.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Peptidase_M18 PF02127.15 ORX90619.1 - 3.9e-178 592.7 0.1 4.5e-178 592.5 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORX90619.1 - 8.9e-09 34.8 0.2 9.1e-08 31.5 0.1 2.3 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Cation_efflux PF01545.21 ORX90620.1 - 1.9e-10 40.8 9.0 2.9e-10 40.2 9.0 1.3 1 0 0 1 1 1 1 Cation efflux family DUF5562 PF17717.1 ORX90620.1 - 0.03 14.3 0.2 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5562) NicO PF03824.16 ORX90620.1 - 7.8 5.7 16.4 15 4.8 16.4 1.5 1 0 0 1 1 1 0 High-affinity nickel-transport protein Cyt-b5 PF00173.28 ORX90622.1 - 1.1e-12 47.9 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 ORX90622.1 - 1.4e-10 41.5 17.4 1.4e-10 41.5 17.4 2.5 1 1 2 3 3 3 2 Fatty acid desaturase Pkinase PF00069.25 ORX90623.1 - 3.2e-71 239.8 0.1 5e-71 239.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90623.1 - 5.6e-50 170.0 0.1 9.8e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX90623.1 - 1.2e-20 73.6 0.0 2.3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORX90623.1 - 7.3e-15 55.4 0.4 2e-14 54.0 0.4 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORX90623.1 - 2.7e-06 26.9 0.1 7.5e-06 25.5 0.1 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORX90623.1 - 1.8e-05 23.7 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORX90623.1 - 0.00047 20.6 0.8 0.13 12.7 0.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 ORX90623.1 - 0.003 17.5 0.1 0.26 11.2 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH_9 PF15410.6 ORX90623.1 - 0.0065 16.8 0.4 0.68 10.3 0.2 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain DSHCT PF08148.12 ORX90623.1 - 0.023 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 ORX90623.1 - 0.04 12.8 1.3 0.081 11.8 1.3 1.4 1 1 0 1 1 1 0 Haspin like kinase domain UQ_con PF00179.26 ORX90626.1 - 4e-38 130.2 0.2 4.7e-38 130.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX90626.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain PhoLip_ATPase_C PF16212.5 ORX90627.1 - 6.8e-67 225.8 36.8 6.8e-67 225.8 36.8 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX90627.1 - 2.4e-23 81.6 1.8 1.3e-22 79.3 1.8 2.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORX90627.1 - 6.6e-12 45.4 0.0 5.4e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX90627.1 - 4.4e-09 36.9 0.0 0.0016 18.8 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX90627.1 - 0.00014 21.7 1.3 0.00043 20.1 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX90627.1 - 0.00026 20.5 5.6 0.00039 20.0 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Mgm101p PF06420.12 ORX90627.1 - 0.018 14.6 0.0 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial genome maintenance MGM101 bZIP_2 PF07716.15 ORX90628.1 - 0.0011 19.0 14.0 0.0011 19.0 14.0 2.5 1 1 1 2 2 2 1 Basic region leucine zipper PH_9 PF15410.6 ORX90629.1 - 1.3e-13 51.4 0.1 2.8e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORX90629.1 - 6.7e-13 49.1 0.2 1.1e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORX90629.1 - 0.074 13.5 0.5 0.22 11.9 0.5 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain His_biosynth PF00977.21 ORX90630.1 - 3.5e-38 131.4 0.0 4.1e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.19 ORX90630.1 - 0.026 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase nos_propeller PF18764.1 ORX90630.1 - 0.19 11.6 0.0 8.2 6.4 0.0 2.4 1 1 1 2 2 2 0 Nitrous oxide reductase propeller repeat DUF2062 PF09835.9 ORX90631.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF3810 PF12725.7 ORX90631.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) YqeY PF09424.10 ORX90632.1 - 8.9e-35 119.9 6.6 1e-34 119.7 6.6 1.1 1 0 0 1 1 1 1 Yqey-like protein RGS PF00615.19 ORX90632.1 - 0.11 12.7 0.6 9.7 6.5 0.1 2.1 1 1 1 2 2 2 0 Regulator of G protein signaling domain Fasciclin PF02469.22 ORX90633.1 - 1.6e-34 118.9 3.9 7.7e-20 71.4 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain MMR_HSR1 PF01926.23 ORX90634.1 - 9.5e-24 83.7 0.1 1.7e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX90634.1 - 1.8e-09 37.3 0.1 2.8e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX90634.1 - 2.5e-09 37.3 0.1 3.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORX90634.1 - 8.8e-07 29.1 0.6 0.016 15.2 0.7 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 ORX90634.1 - 2.6e-05 23.7 0.7 0.00026 20.4 0.7 2.1 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 ORX90634.1 - 0.00015 21.4 1.0 0.0053 16.3 0.6 2.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORX90634.1 - 0.00074 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORX90634.1 - 0.0019 17.8 0.6 0.019 14.6 0.6 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORX90634.1 - 0.0042 17.3 0.7 0.022 15.0 0.7 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 ORX90634.1 - 0.0078 15.6 0.1 2.5 7.5 0.0 2.6 2 1 1 3 3 3 2 Bacterial TniB protein PduV-EutP PF10662.9 ORX90634.1 - 0.051 13.3 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORX90634.1 - 0.056 14.0 0.1 0.078 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DEAD PF00270.29 ORX90635.1 - 1e-44 152.4 0.2 2.6e-44 151.1 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90635.1 - 6e-30 103.8 0.8 3.5e-25 88.5 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90635.1 - 8.7e-06 25.8 0.1 8.7e-06 25.8 0.1 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORX90635.1 - 0.0097 16.2 0.3 0.43 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain SAD_SRA PF02182.17 ORX90637.1 - 8.7e-52 175.0 0.0 1.7e-51 174.0 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain ubiquitin PF00240.23 ORX90637.1 - 3.9e-15 55.4 0.1 6.9e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family PHD PF00628.29 ORX90637.1 - 3e-11 43.0 8.2 3e-11 43.0 8.2 4.1 3 1 1 4 4 3 1 PHD-finger zf-C3HC4_2 PF13923.6 ORX90637.1 - 7.3e-07 28.9 15.6 7.3e-07 28.9 15.6 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX90637.1 - 1.5e-05 24.8 11.3 1.5e-05 24.8 11.3 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX90637.1 - 9.3e-05 22.4 6.5 9.3e-05 22.4 6.5 3.8 3 1 0 3 3 3 1 RING-type zinc-finger Rad60-SLD PF11976.8 ORX90637.1 - 0.00011 21.9 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4 PF00097.25 ORX90637.1 - 0.00011 21.9 14.0 0.00011 21.9 14.0 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORX90637.1 - 0.00015 21.6 3.9 0.00015 21.6 3.9 2.5 3 0 0 3 3 2 1 zf-RING of BARD1-type protein PHD_2 PF13831.6 ORX90637.1 - 0.00027 20.4 1.1 0.00027 20.4 1.1 3.6 6 0 0 6 6 4 1 PHD-finger zf-RING_2 PF13639.6 ORX90637.1 - 0.00048 20.4 12.7 0.00048 20.4 12.7 2.8 2 1 0 2 2 2 1 Ring finger domain Siva PF05458.12 ORX90637.1 - 0.00096 18.9 5.0 0.00096 18.9 5.0 2.3 2 0 0 2 2 2 1 Cd27 binding protein (Siva) DUF2407 PF10302.9 ORX90637.1 - 0.0018 18.8 1.0 0.0025 18.3 0.0 1.8 2 0 0 2 2 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORX90637.1 - 0.0028 17.7 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_5 PF14634.6 ORX90637.1 - 0.003 17.5 11.6 0.003 17.5 11.6 4.1 2 2 2 4 4 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORX90637.1 - 0.0034 17.1 4.3 0.0034 17.1 4.3 4.1 3 1 1 4 4 2 1 RING/Ubox like zinc-binding domain U-box PF04564.15 ORX90637.1 - 0.062 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 U-box domain UBZ_FAAP20 PF15750.5 ORX90637.1 - 0.083 12.9 0.3 0.083 12.9 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Ubiquitin_5 PF18037.1 ORX90637.1 - 0.17 12.3 2.0 0.2 12.1 0.0 2.1 3 0 0 3 3 2 0 Ubiquitin-like domain zf-rbx1 PF12678.7 ORX90637.1 - 1.1 9.6 28.1 0.44 10.9 8.3 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain GLTP PF08718.11 ORX90638.1 - 3.4e-50 170.2 0.1 1.7e-49 167.9 0.0 1.8 1 1 1 2 2 2 1 Glycolipid transfer protein (GLTP) OmpH PF03938.14 ORX90638.1 - 0.14 12.5 0.0 14 6.1 0.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ribosomal_L4 PF00573.22 ORX90639.1 - 3.1e-40 137.9 1.8 5e-40 137.2 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORX90639.1 - 8.6e-30 102.6 2.2 8.6e-30 102.6 2.2 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain RSN1_7TM PF02714.15 ORX90640.1 - 1.2e-46 159.2 19.4 1.2e-46 159.2 19.4 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORX90640.1 - 1.5e-33 115.8 1.9 4.2e-33 114.3 1.9 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORX90640.1 - 2.3e-29 102.9 0.0 5.2e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.25 ORX90641.1 - 2.4e-62 210.7 0.0 2.8e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90641.1 - 1.5e-47 162.1 0.0 1.8e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX90641.1 - 7.2e-07 28.3 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX90641.1 - 0.00073 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORX90641.1 - 0.014 15.3 0.0 0.054 13.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX90641.1 - 0.023 13.6 0.0 0.063 12.2 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORX90641.1 - 0.03 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pescadillo_N PF06732.11 ORX90642.1 - 6.6e-127 422.7 2.1 6.6e-127 422.7 2.1 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 ORX90642.1 - 2.6e-08 34.2 0.6 3.2e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORX90642.1 - 0.00011 22.5 0.0 0.00056 20.2 0.0 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nop53 PF07767.11 ORX90642.1 - 0.0028 17.1 19.2 0.0028 17.1 19.2 2.1 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) LIG3_BRCT PF16759.5 ORX90642.1 - 0.048 14.0 0.9 0.39 11.0 0.1 2.9 2 1 0 2 2 2 0 DNA ligase 3 BRCT domain BNIP2 PF12496.8 ORX90642.1 - 3.3 8.2 8.8 0.23 11.9 2.0 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Exo_endo_phos PF03372.23 ORX90643.1 - 1.2e-15 57.7 0.1 2.1e-15 56.9 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4233 PF14017.6 ORX90643.1 - 0.022 15.1 3.7 0.039 14.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Arm PF00514.23 ORX90644.1 - 1.3e-93 304.5 12.6 6.7e-13 48.2 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 ORX90644.1 - 2.9e-25 88.5 5.1 5.7e-25 87.6 5.1 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 ORX90644.1 - 3.8e-23 80.8 2.4 1e-22 79.4 2.4 1.8 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 ORX90644.1 - 1.2e-20 73.6 4.4 2.8e-05 24.5 0.0 6.4 6 1 1 7 7 6 3 HEAT-like repeat HEAT_2 PF13646.6 ORX90644.1 - 1.5e-17 63.7 0.2 5.7e-06 26.6 0.0 5.6 3 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 ORX90644.1 - 1e-13 50.2 0.9 0.0014 18.7 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 ORX90644.1 - 1.3e-06 27.2 0.0 0.00017 20.3 0.0 2.9 1 1 1 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 ORX90644.1 - 4.6e-06 26.7 0.0 0.21 11.7 0.0 4.4 3 2 2 5 5 5 3 V-ATPase subunit H Arm_2 PF04826.13 ORX90644.1 - 7.2e-05 22.4 0.0 0.2 11.1 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like RICTOR_V PF14668.6 ORX90644.1 - 0.00038 20.6 2.6 0.61 10.4 0.2 4.5 2 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 ORX90644.1 - 0.0022 17.6 0.1 2.2 7.8 0.0 4.1 1 1 3 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 ORX90644.1 - 0.0055 16.1 0.2 0.24 10.7 0.0 2.6 1 1 0 2 2 2 1 Mo25-like SEN1_N PF12726.7 ORX90644.1 - 0.026 12.8 0.1 9.8 4.2 0.0 3.3 3 1 1 4 4 4 0 SEN1 N terminal Atx10homo_assoc PF09759.9 ORX90644.1 - 0.027 14.5 0.3 4.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Nipped-B_C PF12830.7 ORX90644.1 - 0.031 14.2 0.4 4 7.3 0.1 2.8 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus HEAT_PBS PF03130.16 ORX90644.1 - 0.27 12.0 1.2 10 7.1 0.1 3.8 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat PSII_Pbs27 PF13326.6 ORX90645.1 - 0.03 14.6 0.1 0.91 9.8 0.0 2.5 2 0 0 2 2 2 0 Photosystem II Pbs27 Pkinase PF00069.25 ORX90646.1 - 1.9e-80 270.0 0.0 2.2e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90646.1 - 2.5e-36 125.3 0.0 3.1e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX90646.1 - 0.00013 21.4 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORX90646.1 - 0.00025 21.1 0.1 0.0034 17.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX90646.1 - 0.0003 19.8 0.0 0.0034 16.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX90646.1 - 0.0012 18.2 0.1 0.0044 16.4 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORX90646.1 - 0.056 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 ORX90646.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 1 0 1 1 1 0 RIO1 family cobW PF02492.19 ORX90648.1 - 6.6e-34 117.0 0.0 8.3e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORX90648.1 - 0.00034 19.7 0.5 0.0055 15.7 0.5 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 ORX90648.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 ORX90648.1 - 0.0032 18.0 0.0 0.0073 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX90648.1 - 0.0048 17.3 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Pox_A32 PF04665.12 ORX90648.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_5 PF07728.14 ORX90648.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORX90648.1 - 0.043 13.4 0.0 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 ORX90648.1 - 0.046 13.7 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 ORX90648.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 ORX90648.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 ORX90648.1 - 0.16 12.2 0.0 3.3 8.0 0.0 2.4 2 1 1 3 3 3 0 AAA domain TIP49 PF06068.13 ORX90648.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 ORX90648.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Apolipoprotein PF01442.18 ORX90649.1 - 4.5e-05 23.4 28.8 0.0055 16.6 19.3 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORX90649.1 - 0.00033 21.2 31.5 0.028 15.0 4.8 4.5 2 1 3 5 5 5 4 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.6 ORX90649.1 - 0.0047 17.2 0.6 0.0047 17.2 0.6 5.2 2 1 2 4 4 4 1 MT0933-like antitoxin protein YtxH PF12732.7 ORX90649.1 - 0.042 14.4 36.1 17 6.1 3.9 5.1 1 1 2 3 3 3 0 YtxH-like protein Muted PF14942.6 ORX90649.1 - 0.74 10.2 16.9 1.7 9.0 12.2 2.7 1 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein DUF3584 PF12128.8 ORX90649.1 - 4.4 4.7 24.8 5.7 4.3 24.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 ORX90649.1 - 5.1 7.3 13.9 1.9 8.7 10.3 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 ORX90649.1 - 9.7 6.3 33.7 7.9 6.6 17.2 3.5 1 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 ORX90650.1 - 5.9e-08 32.8 40.2 0.00046 20.1 17.8 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORX90650.1 - 4.7e-06 27.1 41.4 0.077 13.6 1.5 4.7 1 1 4 5 5 5 5 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.6 ORX90650.1 - 0.0063 16.8 0.7 0.0063 16.8 0.7 5.9 1 1 3 4 4 4 1 MT0933-like antitoxin protein YtxH PF12732.7 ORX90650.1 - 0.011 16.2 47.2 2.5 8.7 6.3 5.8 1 1 1 2 2 2 0 YtxH-like protein SF-assemblin PF06705.11 ORX90650.1 - 0.031 13.6 26.4 0.02 14.3 4.0 2.1 2 0 0 2 2 2 0 SF-assemblin/beta giardin ApoLp-III PF07464.11 ORX90650.1 - 0.45 10.6 45.4 0.091 12.9 12.7 3.3 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ISG65-75 PF11727.8 ORX90650.1 - 1.3 8.2 51.6 0.62 9.3 16.4 3.1 1 1 2 3 3 3 0 Invariant surface glycoprotein DUF1664 PF07889.12 ORX90650.1 - 2.2 8.4 20.9 2 8.5 4.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 ORX90650.1 - 8.2 5.9 25.3 2.1 7.8 5.4 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Muted PF14942.6 ORX90650.1 - 8.2 6.8 28.5 3.3 8.1 13.4 3.0 1 1 3 4 4 4 0 Organelle biogenesis, Muted-like protein RAI16-like PF10257.9 ORX90651.1 - 2.8e-70 237.0 0.1 7.4e-70 235.6 0.1 1.7 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein WD40 PF00400.32 ORX90652.1 - 1.3e-50 168.2 8.7 7.1e-11 42.5 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90652.1 - 1.1e-14 54.4 0.5 0.004 17.4 0.0 5.3 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX90652.1 - 1.8e-08 33.7 1.7 0.062 12.3 0.0 4.7 2 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX90652.1 - 1.7e-05 23.7 3.1 2.6 6.6 0.0 4.4 2 2 1 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORX90652.1 - 8.3e-05 21.7 1.6 0.00033 19.7 0.0 2.7 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 ORX90652.1 - 0.005 15.2 0.0 0.008 14.5 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORX90652.1 - 0.04 12.6 0.2 3 6.5 0.0 3.5 2 2 0 3 3 3 0 Nup133 N terminal like Coatomer_WDAD PF04053.14 ORX90652.1 - 0.16 10.9 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Metallophos PF00149.28 ORX90653.1 - 8.8e-33 114.5 0.2 1.4e-32 113.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 ORX90653.1 - 2.8e-10 40.4 0.6 2.8e-10 40.4 0.6 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region Sec62 PF03839.16 ORX90654.1 - 1.7e-45 155.2 1.3 2.2e-45 154.8 1.3 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 ORX90654.1 - 0.0046 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Holin_SPP1 PF04688.13 ORX90654.1 - 0.19 11.9 0.6 0.33 11.2 0.6 1.5 1 0 0 1 1 1 0 SPP1 phage holin SPC12 PF06645.13 ORX90654.1 - 0.88 9.7 4.6 0.34 11.0 1.4 2.0 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) EF-hand_1 PF00036.32 ORX90655.1 - 1.5e-27 93.0 10.2 2.6e-08 32.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX90655.1 - 3.2e-23 82.0 5.5 3.2e-13 49.9 0.9 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX90655.1 - 1.7e-21 74.2 5.7 4.3e-05 23.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORX90655.1 - 1.5e-20 71.7 13.7 3e-07 29.6 0.6 4.4 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORX90655.1 - 1e-15 57.3 8.3 8.4e-05 22.3 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX90655.1 - 4.7e-06 26.9 0.0 0.012 15.9 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORX90655.1 - 0.0011 19.3 0.1 0.54 10.6 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 ORX90655.1 - 0.0018 18.2 6.4 1.9 8.5 0.2 3.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Anthrax-tox_M PF09156.10 ORX90655.1 - 0.019 14.3 0.3 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain Dockerin_1 PF00404.18 ORX90655.1 - 0.068 13.4 1.5 5 7.4 1.8 2.9 2 1 1 3 3 3 0 Dockerin type I domain Sigma54_CBD PF04963.13 ORX90655.1 - 0.074 12.9 0.1 1.1 9.1 0.0 2.4 1 1 2 3 3 3 0 Sigma-54 factor, core binding domain Nse4-Nse3_bdg PF15412.6 ORX90655.1 - 0.079 13.1 2.1 22 5.3 0.1 3.4 3 1 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE Tim17 PF02466.19 ORX90656.1 - 7e-06 26.4 1.8 3.2e-05 24.3 1.8 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 ORX90656.1 - 0.0075 15.9 0.4 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF533) HDOD PF08668.12 ORX90656.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 HDOD domain PPR_2 PF13041.6 ORX90657.1 - 7.2e-29 99.7 0.7 1.1e-17 63.9 0.0 4.8 4 1 2 6 6 6 4 PPR repeat family PPR PF01535.20 ORX90657.1 - 4.1e-17 61.1 5.1 8.2e-07 28.9 0.0 6.8 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.7 ORX90657.1 - 6.8e-15 54.5 0.4 0.0021 17.7 0.0 5.6 6 0 0 6 6 6 4 PPR repeat PPR_3 PF13812.6 ORX90657.1 - 1e-11 44.7 0.0 0.00059 19.9 0.0 4.2 3 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX90657.1 - 9.2e-11 41.5 0.1 1.3e-09 37.8 0.0 2.4 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 ORX90657.1 - 0.00058 19.7 0.1 0.01 15.7 0.0 2.9 3 1 0 3 3 3 1 Mitochondrial ATPase expression PYRIN PF02758.16 ORX90657.1 - 0.16 12.2 0.0 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain PPR_2 PF13041.6 ORX90658.1 - 4.8e-84 276.4 13.9 1.5e-14 53.9 0.6 9.3 5 3 4 9 9 9 9 PPR repeat family PPR PF01535.20 ORX90658.1 - 2.5e-53 174.7 15.0 9.4e-10 38.1 0.0 11.8 12 1 0 12 12 12 8 PPR repeat PPR_3 PF13812.6 ORX90658.1 - 1.7e-49 165.7 14.7 4.7e-11 42.6 0.6 7.7 4 2 3 8 8 8 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX90658.1 - 2.7e-47 158.1 21.5 2.2e-10 40.1 0.0 11.4 13 0 0 13 13 13 7 PPR repeat PPR_long PF17177.4 ORX90658.1 - 4.6e-28 98.0 0.9 5.2e-10 39.0 0.0 4.0 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX90658.1 - 6.3e-05 23.4 9.8 0.31 11.5 0.0 5.8 4 2 1 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 ORX90658.1 - 0.0045 16.9 0.0 15 5.9 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX90658.1 - 0.011 15.5 2.6 24 5.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat CSTF2_hinge PF14327.6 ORX90658.1 - 0.036 14.5 0.2 8.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 Vps8 PF12816.7 ORX90658.1 - 0.06 12.8 0.0 8.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 Glu-tRNAGln PF02686.15 ORX90658.1 - 0.11 12.8 0.1 1.6 9.1 0.0 2.9 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DnaJ PF00226.31 ORX90659.1 - 4.9e-24 84.2 0.9 4.9e-24 84.2 0.9 2.4 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.7 ORX90659.1 - 1.3e-10 41.3 8.8 6.7e-08 32.7 3.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX90659.1 - 6.2e-10 39.1 11.1 7.8e-10 38.8 4.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORX90659.1 - 1.8e-05 25.2 2.1 0.24 12.3 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORX90659.1 - 0.00041 20.7 11.3 0.043 14.1 0.1 3.9 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORX90659.1 - 0.001 19.4 3.6 0.38 11.3 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORX90659.1 - 0.0068 16.4 11.1 0.75 9.9 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger MCD PF05292.11 ORX90660.1 - 8.6e-99 330.3 0.0 1.2e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 ORX90660.1 - 2.4e-14 53.2 0.0 4.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain FIVAR PF07554.13 ORX90660.1 - 0.35 11.6 2.7 0.54 11.1 1.0 2.1 2 0 0 2 2 2 0 FIVAR domain Sdh5 PF03937.16 ORX90661.1 - 6.5e-27 93.3 0.2 9.3e-27 92.8 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase SNF2_N PF00176.23 ORX90662.1 - 2.8e-68 230.2 0.0 5.2e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX90662.1 - 1e-17 64.4 0.0 3e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90662.1 - 1.9e-08 34.5 0.0 1.7e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORX90662.1 - 0.0005 19.3 1.5 0.0037 16.5 0.0 2.9 3 2 1 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 ABC_tran_CTD PF16326.5 ORX90662.1 - 0.0046 17.2 9.5 0.011 16.0 9.5 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain Cauli_AT PF03233.13 ORX90662.1 - 0.031 14.2 7.9 0.097 12.6 7.9 1.9 1 0 0 1 1 1 0 Aphid transmission protein SPATA6 PF14909.6 ORX90662.1 - 0.12 12.5 1.2 0.26 11.4 1.2 1.5 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 AAA_11 PF13086.6 ORX90662.1 - 8.8 6.0 0.0 8.8 6.0 0.0 3.5 3 1 1 4 4 4 0 AAA domain Carb_anhydrase PF00194.21 ORX90667.1 - 3.7e-45 154.5 0.0 5.6e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Metallophos PF00149.28 ORX90668.1 - 1.5e-12 48.5 0.8 2.2e-12 47.9 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 ORX90668.1 - 0.0025 16.2 0.1 0.013 13.8 0.0 2.0 3 0 0 3 3 3 1 Firmicute fructose-1,6-bisphosphatase Arrestin_N PF00339.29 ORX90669.1 - 1.1e-08 35.3 0.2 1.3e-07 31.8 0.1 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX90669.1 - 1e-06 29.2 0.8 8.1e-06 26.3 0.3 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX90669.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Arrestin_C PF02752.22 ORX90670.1 - 1.4e-14 54.7 0.4 8e-09 36.1 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90670.1 - 3e-10 40.3 0.1 2e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX90670.1 - 0.041 13.6 0.1 0.13 11.9 0.0 1.8 1 1 1 2 2 2 0 Arrestin_N terminal like Carn_acyltransf PF00755.20 ORX90671.1 - 2.4e-193 644.0 0.0 2.9e-193 643.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TNF PF00229.18 ORX90671.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family Carn_acyltransf PF00755.20 ORX90672.1 - 1.5e-187 624.9 0.0 1.7e-187 624.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SH3_1 PF00018.28 ORX90673.1 - 3.6e-06 26.5 0.0 5.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX90673.1 - 4.9e-06 26.3 0.1 9.1e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX90673.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Myb_DNA-binding PF00249.31 ORX90675.1 - 1.6e-23 82.6 1.7 1.4e-09 38.0 0.0 4.1 3 2 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX90675.1 - 2.2e-17 63.1 0.2 2.5e-11 43.6 0.1 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF5591 PF17884.1 ORX90675.1 - 0.11 12.3 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5591) MPP6 PF10175.9 ORX90676.1 - 3.2e-21 76.2 12.4 3.8e-21 76.0 12.4 1.0 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 ORX90676.1 - 0.0002 20.1 11.0 0.00023 19.9 11.0 1.0 1 0 0 1 1 1 1 Utp14 protein ERM PF00769.19 ORX90677.1 - 0.00056 19.8 29.9 0.00056 19.8 29.9 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family GAS PF13851.6 ORX90677.1 - 0.0011 18.4 15.5 0.0011 18.4 15.5 2.8 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 ORX90677.1 - 0.008 16.2 19.4 0.008 16.2 19.4 2.9 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 ORX90677.1 - 0.021 15.1 0.6 0.021 15.1 0.6 4.7 5 1 0 5 5 5 0 Homeobox associated leucine zipper Spectrin PF00435.21 ORX90677.1 - 0.084 13.4 21.1 1.2 9.6 7.5 3.5 3 0 0 3 3 3 0 Spectrin repeat DUF1319 PF07028.11 ORX90677.1 - 0.32 11.2 10.1 0.18 12.0 1.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) BRE1 PF08647.11 ORX90677.1 - 0.43 10.7 27.4 0.052 13.6 6.8 4.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 ORX90677.1 - 0.62 10.4 4.6 0.9 9.8 0.1 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 ORX90677.1 - 1.3 9.4 31.9 0.13 12.7 12.4 2.7 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 ORX90677.1 - 1.6 8.0 27.7 2.1 7.6 22.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 ORX90677.1 - 1.8 9.3 26.3 0.51 11.0 5.7 3.9 2 1 2 4 4 4 0 Initiation control protein YabA ATG16 PF08614.11 ORX90677.1 - 1.8 8.7 38.3 2.3 8.4 30.2 3.0 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 ORX90677.1 - 2.8 7.5 35.8 0.52 9.9 21.4 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMPIT PF07851.13 ORX90677.1 - 4 6.6 19.9 0.092 12.0 8.4 2.4 1 1 1 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 ORX90677.1 - 4.2 7.4 39.6 1.4 9.0 17.2 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 ORX90677.1 - 4.3 6.1 36.4 0.2 10.5 17.5 3.0 2 1 2 4 4 4 0 Spc7 kinetochore protein Metal_resist PF13801.6 ORX90677.1 - 6.2 7.0 13.0 15 5.8 2.6 2.9 2 1 0 2 2 2 0 Heavy-metal resistance Rpn3_C PF08375.11 ORX90678.1 - 2.1e-30 104.9 5.0 2.8e-30 104.5 3.2 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 ORX90678.1 - 1e-21 77.4 2.7 1.6e-21 76.8 0.1 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 ORX90678.1 - 0.67 10.2 8.7 0.28 11.4 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat G-gamma PF00631.22 ORX90679.1 - 1.8e-13 50.2 0.0 1.9e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain MAM33 PF02330.16 ORX90680.1 - 2.6e-23 83.1 0.1 3.1e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein PTCB-BRCT PF12738.7 ORX90684.1 - 1.2e-31 108.4 1.7 8.5e-11 41.7 0.0 4.2 3 1 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 ORX90684.1 - 7.7e-26 90.3 0.1 2.1e-13 50.5 0.0 2.5 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORX90684.1 - 7.6e-09 35.9 0.1 0.002 18.5 0.0 2.6 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 ORX90684.1 - 0.0067 16.3 0.0 0.17 11.8 0.0 2.7 3 1 1 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 ORX90684.1 - 0.094 13.0 0.0 27 5.2 0.0 2.8 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain NPA PF16469.5 ORX90685.1 - 0.0031 18.1 0.4 0.006 17.1 0.4 1.4 1 0 0 1 1 1 1 Nematode polyprotein allergen ABA-1 Beta-Casp PF10996.8 ORX90685.1 - 0.064 13.6 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 Beta-Casp domain SIS PF01380.22 ORX90688.1 - 7.9e-24 84.0 0.0 1.8e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 ORX90688.1 - 1.8e-19 69.9 1.6 6.3e-09 36.1 0.4 2.9 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 ORX90688.1 - 4e-06 26.9 0.0 0.016 15.2 0.0 2.5 1 1 1 2 2 2 2 SIS domain La PF05383.17 ORX90690.1 - 1.2e-25 89.3 0.1 2.6e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 ORX90690.1 - 9.9e-15 54.4 4.8 1.9e-13 50.4 0.3 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_1 PF00076.22 ORX90690.1 - 1.5e-11 43.9 3.3 1e-09 38.1 0.2 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4850 PF16142.5 ORX90690.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) CRISPR_Cas2 PF09827.9 ORX90690.1 - 0.099 12.8 0.0 3.2 8.0 0.0 2.6 1 1 1 2 2 2 0 CRISPR associated protein Cas2 PHM7_cyt PF14703.6 ORX90690.1 - 0.32 11.2 4.0 5.8 7.1 0.0 3.3 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF962 PF06127.11 ORX90691.1 - 2.7e-24 85.1 1.2 4.7e-24 84.3 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Metallophos PF00149.28 ORX90692.1 - 1.8e-14 54.7 0.0 2.3e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX90692.1 - 1.5e-10 41.5 0.0 3.2e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORX90692.1 - 0.0044 16.4 0.1 0.0086 15.4 0.1 1.5 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily MFS_1 PF07690.16 ORX90693.1 - 1.3e-28 100.0 29.2 1.3e-28 100.0 29.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX90693.1 - 1.6e-08 33.9 18.4 9.8e-05 21.4 0.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Acetyltransf_7 PF13508.7 ORX90694.1 - 7.7e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX90694.1 - 2.1e-07 31.2 0.0 3.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX90694.1 - 7.5e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX90694.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Myb_DNA-bind_4 PF13837.6 ORX90695.1 - 3.5e-31 107.4 13.2 1.7e-15 57.2 4.0 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX90695.1 - 2.5e-13 50.1 8.2 1.7e-06 28.2 2.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX90695.1 - 4.3e-08 33.2 6.6 0.00069 19.8 0.9 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORX90695.1 - 2.5e-07 31.6 8.7 0.0012 19.8 2.3 2.2 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORX90695.1 - 0.01 15.9 8.7 0.062 13.4 1.4 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SAE2 PF08573.10 ORX90695.1 - 0.037 15.1 2.1 2.7 9.1 0.3 2.4 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus NOP5NT PF08156.13 ORX90695.1 - 0.047 14.1 0.0 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 NOP5NT (NUC127) domain ARID PF01388.21 ORX90695.1 - 0.1 13.3 0.8 13 6.6 0.1 3.0 2 1 0 2 2 2 0 ARID/BRIGHT DNA binding domain RQC PF09382.10 ORX90695.1 - 0.18 11.6 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 RQC domain ATG_C PF09333.11 ORX90696.1 - 3.7e-31 107.3 0.1 8.2e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 ORX90696.1 - 4.2e-22 78.5 0.1 1.2e-21 77.0 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 ORX90696.1 - 5.7e-20 71.6 0.2 1.7e-19 70.1 0.2 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 ORX90696.1 - 8.6e-07 28.9 0.0 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal DNA_pol_E_B PF04042.16 ORX90697.1 - 2.6e-38 131.5 0.3 6.6e-38 130.2 0.4 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 ORX90697.1 - 2.4e-33 116.1 0.7 3.6e-33 115.6 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal MAGI_u1 PF16663.5 ORX90697.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI DUF1647 PF07801.11 ORX90698.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Hist_deacetyl PF00850.19 ORX90698.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain DUF1647 PF07801.11 ORX90699.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Pkinase PF00069.25 ORX90700.1 - 4.6e-70 236.0 0.1 6.5e-70 235.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90700.1 - 5.7e-51 173.3 0.1 9.3e-51 172.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX90700.1 - 3.5e-21 75.3 0.0 7.5e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORX90700.1 - 4e-14 53.0 0.3 9.3e-14 51.8 0.3 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORX90700.1 - 6.6e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX90700.1 - 7.6e-06 24.9 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORX90700.1 - 0.0013 19.1 0.7 1 9.8 0.0 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain APH PF01636.23 ORX90700.1 - 0.0018 18.2 0.2 0.048 13.6 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH_9 PF15410.6 ORX90700.1 - 0.0032 17.8 0.1 0.037 14.4 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain RIO1 PF01163.22 ORX90700.1 - 0.0054 16.3 0.2 0.014 15.0 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORX90700.1 - 0.043 12.7 1.5 0.14 11.1 1.5 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FA_desaturase PF00487.24 ORX90701.1 - 2.2e-32 112.9 26.2 6e-32 111.5 23.4 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 ORX90701.1 - 8.1e-13 48.3 0.1 1.6e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_U4 PF03419.13 ORX90701.1 - 0.22 10.8 4.2 0.14 11.5 1.4 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Metallophos PF00149.28 ORX90702.1 - 1.1e-36 127.3 0.1 1.4e-36 127.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 ORX90702.1 - 0.054 13.1 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 ORX90702.1 - 0.099 13.1 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HRG PF16954.5 ORX90703.1 - 0.022 15.2 1.9 6.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene MASE1 PF05231.14 ORX90703.1 - 0.73 8.9 7.8 0.32 10.1 1.5 2.0 2 0 0 2 2 2 0 MASE1 His_Phos_1 PF00300.22 ORX90704.1 - 3e-41 141.2 0.0 3.6e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LtuB PF17455.2 ORX90704.1 - 0.037 14.6 0.1 0.2 12.3 0.0 2.1 2 0 0 2 2 2 0 Late transcription unit B Trigger_C PF05698.14 ORX90704.1 - 0.059 13.4 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus BRCT_2 PF16589.5 ORX90704.1 - 0.15 12.5 0.0 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Exo_endo_phos PF03372.23 ORX90705.1 - 2.9e-13 49.9 0.0 4.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PapD-like PF14874.6 ORX90705.1 - 0.011 15.8 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Flagellar-associated PapD-like HSP70 PF00012.20 ORX90708.1 - 1.9e-124 416.1 0.2 2.1e-124 415.9 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX90708.1 - 5.5e-11 41.8 0.0 8.2e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 ORX90708.1 - 0.0029 16.9 0.2 0.0039 16.5 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.11 ORX90708.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 StbA protein Metallophos PF00149.28 ORX90710.1 - 2.5e-15 57.6 0.1 4.4e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX90710.1 - 0.0011 19.1 0.0 0.0068 16.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain m_DGTX_Dc1a_b_c PF17491.2 ORX90710.1 - 0.0015 19.1 0.1 0.29 11.8 0.0 3.6 4 0 0 4 4 4 1 Spider Toxins mu-diguetoxin-1 a, b and c SBDS PF01172.18 ORX90711.1 - 5.1e-21 74.5 0.1 7.3e-21 74.1 0.1 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RdRP PF05183.12 ORX90712.1 - 3e-162 541.3 0.0 3.7e-162 541.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EF-hand_12 PF17901.1 ORX90712.1 - 0.056 13.9 0.2 2.4 8.7 0.1 2.5 2 0 0 2 2 2 0 EF-hand fold domain ABC_membrane PF00664.23 ORX90713.1 - 2.7e-133 443.8 32.2 4.7e-69 233.1 13.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX90713.1 - 2.6e-72 241.8 0.0 4.9e-36 124.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX90713.1 - 2e-17 63.4 0.3 8.8e-06 25.3 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX90713.1 - 1.2e-07 32.2 0.9 0.036 14.4 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX90713.1 - 2.2e-06 27.3 2.2 0.03 14.1 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORX90713.1 - 5.8e-06 26.3 0.0 0.051 13.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 ORX90713.1 - 1.3e-05 24.2 1.2 0.028 13.2 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORX90713.1 - 4.9e-05 23.6 2.4 0.6 10.4 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORX90713.1 - 0.00012 21.9 0.0 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORX90713.1 - 0.00031 20.5 0.9 0.79 9.4 0.1 3.3 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORX90713.1 - 0.00039 19.7 0.0 0.91 8.8 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 ORX90713.1 - 0.00054 19.9 0.0 1.1 8.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ORX90713.1 - 0.0009 19.7 4.4 1.8 9.0 0.4 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORX90713.1 - 0.00091 19.8 0.0 0.29 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORX90713.1 - 0.0023 17.9 0.1 0.4 10.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 ORX90713.1 - 0.0023 17.9 0.2 5.9 6.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORX90713.1 - 0.0027 17.9 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORX90713.1 - 0.0028 18.2 0.3 1.3 9.5 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORX90713.1 - 0.0032 17.0 0.1 0.83 9.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NDUF_B12 PF08122.12 ORX90713.1 - 0.0038 17.2 0.0 0.016 15.2 0.0 2.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family SbcCD_C PF13558.6 ORX90713.1 - 0.0041 17.3 2.5 4.1 7.7 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 ORX90713.1 - 0.0048 16.1 0.1 0.18 11.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 ORX90713.1 - 0.0057 16.6 0.0 0.72 9.7 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ORX90713.1 - 0.013 15.5 0.0 1.7 8.7 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 ORX90713.1 - 0.014 15.2 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 ORX90713.1 - 0.015 15.7 0.1 18 5.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 ORX90713.1 - 0.028 13.6 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 ORX90713.1 - 0.046 13.1 0.1 0.99 8.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORX90713.1 - 0.048 13.2 0.1 8.5 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX90713.1 - 0.09 13.2 0.0 15 6.0 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 ORX90713.1 - 0.12 12.1 0.1 17 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain TRAM_LAG1_CLN8 PF03798.16 ORX90714.1 - 2.9e-38 131.6 21.4 4.6e-38 131.0 21.4 1.3 1 0 0 1 1 1 1 TLC domain E1-E2_ATPase PF00122.20 ORX90715.1 - 3.1e-52 176.7 3.8 3.1e-52 176.7 3.8 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX90715.1 - 6.8e-36 123.7 10.1 6.8e-36 123.7 10.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORX90715.1 - 2.1e-23 83.7 0.0 1.7e-22 80.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX90715.1 - 5.5e-17 61.2 0.0 6.5e-16 57.8 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORX90715.1 - 4.2e-10 39.6 0.0 9.1e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX90715.1 - 5.6e-08 32.8 0.9 0.00017 21.5 0.6 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ORX90716.1 - 3.7e-71 239.6 0.2 5.2e-71 239.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90716.1 - 1.2e-51 175.5 0.1 1.2e-51 175.5 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 ORX90716.1 - 3.9e-22 78.4 0.0 1e-21 77.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORX90716.1 - 2e-15 57.2 0.4 4.2e-15 56.2 0.4 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORX90716.1 - 1.2e-07 31.4 0.1 4.4e-07 29.5 0.1 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORX90716.1 - 1.1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORX90716.1 - 6.2e-05 23.4 1.4 0.011 16.1 1.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 ORX90716.1 - 0.00025 20.1 1.1 0.00043 19.3 1.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX90716.1 - 0.017 15.0 0.3 0.043 13.7 0.4 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_9 PF15410.6 ORX90716.1 - 0.028 14.8 0.3 4.9 7.5 0.0 2.8 2 1 1 3 3 2 0 Pleckstrin homology domain Seadorna_VP7 PF07387.11 ORX90716.1 - 0.033 13.2 0.3 0.062 12.3 0.3 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORX90716.1 - 0.04 13.3 0.8 0.071 12.5 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_C PF02752.22 ORX90717.1 - 1.4e-14 54.6 0.0 4.9e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90717.1 - 2.4e-09 37.4 0.1 4.1e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX90717.1 - 0.014 14.6 0.2 0.64 9.1 0.0 2.1 2 0 0 2 2 2 0 Rgp1 zf-C2H2 PF00096.26 ORX90718.1 - 7.9e-14 51.2 13.3 4.1e-07 30.1 3.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX90718.1 - 3.3e-11 43.1 17.8 9.6e-08 32.1 4.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX90718.1 - 1.6e-10 40.9 11.1 1.8e-05 25.2 2.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX90718.1 - 8.6e-08 32.0 2.7 8.6e-05 22.4 1.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX90718.1 - 1e-07 32.0 2.5 3.6e-05 23.9 0.6 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX90718.1 - 0.00014 22.2 3.6 0.0041 17.5 0.7 2.5 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORX90718.1 - 0.011 16.4 3.7 0.012 16.2 3.7 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger FOXP-CC PF16159.5 ORX90718.1 - 0.022 15.4 1.3 0.1 13.2 0.1 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-DNA_Pol PF08996.10 ORX90718.1 - 0.03 14.1 0.6 0.031 14.0 0.6 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2_8 PF15909.5 ORX90718.1 - 0.045 14.0 2.3 0.18 12.1 2.3 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 ORX90718.1 - 0.062 13.6 3.4 0.1 12.9 3.4 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 ORX90718.1 - 0.14 11.8 3.2 2.5 7.8 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 ORX90718.1 - 0.21 11.5 3.6 6.1 6.9 0.2 2.4 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 ORX90718.1 - 0.8 9.5 6.8 1.4 8.8 0.6 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-AN1 PF01428.16 ORX90718.1 - 1.1 9.4 8.2 7.7 6.8 4.1 2.4 1 1 0 2 2 2 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 ORX90718.1 - 7 6.5 20.4 1.5 8.6 2.9 3.7 2 2 0 2 2 2 0 C2H2-type zinc-finger domain Polysacc_deac_1 PF01522.21 ORX90719.1 - 2.7e-33 114.5 0.0 3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX90719.1 - 0.038 13.2 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF805 PF05656.14 ORX90719.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF2334 PF10096.9 ORX90719.1 - 0.14 11.8 0.5 0.4 10.3 0.5 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) HMGL-like PF00682.19 ORX90720.1 - 5.5e-88 294.9 0.0 9.1e-88 294.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 ORX90720.1 - 1.9e-30 105.5 2.1 3.3e-30 104.7 2.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain PBD PF00786.28 ORX90722.1 - 9.7e-13 48.3 0.3 6.6e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 P21-Rho-binding domain Latarcin PF10279.9 ORX90728.1 - 0.066 13.6 0.7 0.27 11.7 0.6 1.9 1 1 0 1 1 1 0 Latarcin precursor DUF3472 PF11958.8 ORX90729.1 - 6.7e-11 43.0 0.1 1.2e-10 42.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX90729.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF5077) KH_8 PF17903.1 ORX90731.1 - 1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORX90731.1 - 0.00068 19.4 0.5 0.0013 18.5 0.5 1.4 1 0 0 1 1 1 1 KH domain CK_II_beta PF01214.18 ORX90732.1 - 1.8e-82 275.6 0.1 2.3e-82 275.2 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HAD PF12710.7 ORX90732.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Response_reg PF00072.24 ORX90733.1 - 4.7e-21 75.0 0.0 2e-15 56.9 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain Sulfate_transp PF00916.20 ORX90734.1 - 1.9e-52 178.3 15.9 3.9e-52 177.3 15.9 1.5 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ORX90734.1 - 6.8e-14 51.7 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORX90734.1 - 1.4e-08 34.4 0.1 4.3e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 STAS domain TM_helix PF05552.12 ORX90734.1 - 5.8 7.0 6.3 33 4.6 0.1 3.6 2 1 1 3 3 3 0 Conserved TM helix DHHC PF01529.20 ORX90734.1 - 7.7 6.6 8.4 26 4.9 2.5 2.9 2 1 0 2 2 2 0 DHHC palmitoyltransferase Polysacc_deac_1 PF01522.21 ORX90735.1 - 1e-22 80.3 0.0 1.5e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase THUMP PF02926.17 ORX90736.1 - 3e-22 79.3 3.1 3.3e-22 79.1 0.8 2.0 1 1 1 2 2 2 1 THUMP domain RST PF12174.8 ORX90736.1 - 0.11 12.4 1.0 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain F1F0-ATPsyn_F PF10791.9 ORX90737.1 - 3.4e-22 78.7 0.0 3.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 ORX90737.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Aminotran_4 PF01063.19 ORX90738.1 - 2.6e-18 66.7 0.0 3.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Sec66 PF09802.9 ORX90739.1 - 2.5e-45 154.3 2.4 3e-45 154.0 2.4 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 RabGAP-TBC PF00566.18 ORX90741.1 - 1.7e-56 191.2 0.1 4.2e-56 190.0 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain UPF0160 PF03690.13 ORX90742.1 - 2.6e-135 451.1 0.0 3e-135 451.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Esterase PF00756.20 ORX90743.1 - 1.7e-62 211.4 0.0 1.9e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORX90743.1 - 2.7e-06 27.0 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX90743.1 - 0.00013 21.9 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORX90743.1 - 0.00075 18.8 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORX90743.1 - 0.0032 16.4 0.0 0.0054 15.7 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 ORX90743.1 - 0.026 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 ORX90743.1 - 0.032 13.8 0.0 0.081 12.5 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORX90743.1 - 0.034 14.8 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX90743.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORX90743.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 ORX90743.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S15 PF02129.18 ORX90743.1 - 0.11 12.0 0.0 11 5.6 0.0 2.8 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Fasciclin PF02469.22 ORX90744.1 - 7.5e-86 284.8 0.9 1.1e-19 71.0 0.1 5.4 5 1 0 5 5 5 5 Fasciclin domain BAR_2 PF10455.9 ORX90744.1 - 0.15 11.2 0.1 0.5 9.5 0.0 1.9 3 0 0 3 3 3 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ABC_tran PF00005.27 ORX90745.1 - 1.8e-30 106.2 0.0 3.2e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX90745.1 - 6e-18 65.1 12.7 8.8e-18 64.5 12.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX90745.1 - 2.6e-16 60.3 0.5 3.4e-10 40.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORX90745.1 - 0.00084 19.9 0.1 0.0016 19.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORX90745.1 - 0.0048 16.3 0.1 0.94 8.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORX90745.1 - 0.039 13.7 0.0 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 ORX90745.1 - 0.075 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORX90745.1 - 0.12 12.1 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain SKG6 PF08693.10 ORX90746.1 - 0.00016 21.0 0.8 0.00035 19.9 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ndc1_Nup PF09531.10 ORX90746.1 - 2.6 6.6 9.8 3.8 6.1 9.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RabGAP-TBC PF00566.18 ORX90747.1 - 5.2e-34 117.8 0.9 6.9e-34 117.4 0.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Exonuc_VII_L PF02601.15 ORX90747.1 - 0.098 12.2 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.32 ORX90749.1 - 5.6e-28 96.6 0.6 8.9e-08 32.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90749.1 - 9.5e-10 38.7 0.2 0.3 11.4 0.2 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX90749.1 - 6e-05 21.9 0.3 0.19 10.3 0.1 2.6 2 2 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ORX90749.1 - 0.00029 20.9 0.0 2.1 8.4 0.0 3.3 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region NOA36 PF06524.12 ORX90749.1 - 1.5 8.1 7.3 2.5 7.4 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ORX90749.1 - 6.8 4.7 10.5 8.3 4.4 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DGCR6 PF07324.11 ORX90750.1 - 2.8e-15 56.5 6.3 1.6e-14 54.0 6.3 1.9 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 ORX90750.1 - 1.4e-07 31.4 1.7 2.2e-07 30.7 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF4419 PF14388.6 ORX90750.1 - 0.17 11.3 0.2 0.24 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) ANAPC9 PF12856.7 ORX90751.1 - 0.042 14.0 0.5 0.082 13.1 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Glyco_hydro81C PF17652.1 ORX90752.1 - 1e-95 321.0 0.0 1.2e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 ORX90752.1 - 4.7e-19 68.7 0.0 7.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain EF-hand_4 PF12763.7 ORX90754.1 - 5e-31 106.7 0.0 1.4e-22 79.6 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 ORX90754.1 - 4.9e-17 62.8 19.3 4.9e-17 62.8 19.3 2.8 2 1 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 ORX90754.1 - 5.6e-07 28.7 0.4 1.7e-05 24.0 0.6 3.1 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 ORX90754.1 - 8e-07 29.4 4.5 0.00021 21.7 0.1 3.7 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 ORX90754.1 - 0.00023 20.9 0.3 0.044 13.7 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain AAA_13 PF13166.6 ORX90754.1 - 0.0017 17.1 14.4 0.0022 16.7 14.4 1.1 1 0 0 1 1 1 1 AAA domain DRAT PF07357.11 ORX90754.1 - 0.013 14.7 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF4763 PF15960.5 ORX90754.1 - 0.017 14.4 10.0 0.027 13.8 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) EF-hand_8 PF13833.6 ORX90754.1 - 0.023 14.6 1.3 0.43 10.5 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair HALZ PF02183.18 ORX90754.1 - 0.17 12.1 9.1 0.37 11.1 1.7 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper HrpB7 PF09486.10 ORX90754.1 - 0.96 9.8 10.3 3.4 8.0 10.4 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 ORX90754.1 - 2.9 7.4 13.4 4 6.9 13.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 ORX90754.1 - 5.3 7.4 6.4 30 5.0 0.4 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 ORX90754.1 - 5.5 6.0 22.8 6.1 5.8 13.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4549 PF15082.6 ORX90754.1 - 6.9 6.4 9.6 0.87 9.4 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) DUF4407 PF14362.6 ORX90754.1 - 7 5.9 14.7 12 5.1 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5320 PF17253.2 ORX90754.1 - 7.6 7.7 7.0 29 5.8 0.8 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DEAD PF00270.29 ORX90755.1 - 6.4e-42 143.3 0.5 1.2e-41 142.4 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX90755.1 - 2.3e-34 118.1 1.1 5.3e-32 110.5 0.2 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORX90755.1 - 2.7e-09 37.2 0.1 8.2e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORX90755.1 - 0.00042 19.1 0.0 0.003 16.3 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain AAA_19 PF13245.6 ORX90755.1 - 0.0013 19.1 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX90755.1 - 0.067 13.5 1.3 0.37 11.1 1.3 2.1 1 1 0 1 1 1 0 AAA domain NYN PF01936.18 ORX90755.1 - 0.14 12.7 0.0 0.53 10.8 0.0 2.0 1 0 0 1 1 1 0 NYN domain SAM_LFY PF01698.16 ORX90755.1 - 0.16 11.9 0.0 0.52 10.3 0.0 1.8 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain RabGAP-TBC PF00566.18 ORX90756.1 - 7.4e-43 146.7 0.0 1.2e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 ORX90756.1 - 1.8e-28 99.6 0.0 2.8e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90756.1 - 4.2e-19 68.8 0.0 7.2e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 ORX90756.1 - 3e-09 37.3 0.0 5.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 ORX90756.1 - 0.0041 16.5 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sacchrp_dh_NADP PF03435.18 ORX90757.1 - 0.029 14.6 0.0 0.059 13.6 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 5-FTHF_cyc-lig PF01812.20 ORX90758.1 - 2e-49 168.0 0.0 2.3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family CLP_protease PF00574.23 ORX90758.1 - 0.0088 15.9 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Clp protease CitX PF03802.14 ORX90758.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Cnd1 PF12717.7 ORX90759.1 - 0.031 14.3 1.5 2 8.4 0.1 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 L1R_F9L PF02442.17 ORX90759.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses LOH1CR12 PF10158.9 ORX90760.1 - 5.8e-15 55.5 0.0 1.6e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Tumour suppressor protein BDV_P10 PF06515.11 ORX90760.1 - 0.077 13.0 0.1 1.2 9.2 0.3 2.6 2 0 0 2 2 2 0 Borna disease virus P10 protein DUF1397 PF07165.11 ORX90760.1 - 0.15 11.5 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) T4SS PF07996.11 ORX90760.1 - 1.7 9.0 8.3 0.17 12.3 2.9 2.1 2 1 0 2 2 2 0 Type IV secretion system proteins HLH PF00010.26 ORX90765.1 - 0.00037 20.4 0.2 0.00061 19.7 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Copper-fist PF00649.18 ORX90766.1 - 1.9e-22 78.5 1.8 1.9e-22 78.5 1.8 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain DUF3716 PF12511.8 ORX90766.1 - 0.034 14.2 5.3 2.2 8.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) NPR3 PF03666.13 ORX90767.1 - 0.35 9.6 1.8 0.47 9.2 1.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pyr_redox_2 PF07992.14 ORX90768.1 - 1.8e-47 162.0 0.0 2.4e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX90768.1 - 8.2e-16 58.3 0.0 5e-12 46.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 ORX90768.1 - 5.9e-13 47.4 7.2 1.6e-07 30.4 0.4 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 ORX90768.1 - 8.9e-12 43.9 3.3 1.8e-05 24.3 0.9 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORX90768.1 - 3.1e-11 43.6 0.7 0.00035 20.9 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORX90768.1 - 1.3e-09 37.1 4.6 4.7e-05 22.7 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORX90768.1 - 2e-06 27.6 2.6 0.0013 18.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 ORX90768.1 - 0.00063 19.1 0.1 1.9 7.7 0.7 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.7 ORX90768.1 - 0.014 15.4 0.1 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand NAD_binding_8 PF13450.6 ORX90768.1 - 0.038 14.2 0.0 8 6.8 0.0 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cyclin_N PF00134.23 ORX90769.1 - 2e-16 59.9 0.1 9.5e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORX90769.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Aldo_ket_red PF00248.21 ORX90770.1 - 3.3e-63 213.6 0.0 4.1e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SIMPL PF04402.14 ORX90770.1 - 0.033 14.6 0.0 0.052 14.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Cyclin_N PF00134.23 ORX90771.1 - 4.1e-46 155.9 2.2 7.1e-46 155.1 0.8 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX90771.1 - 7.1e-31 106.8 2.1 1.2e-30 106.0 1.3 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain IES5 PF17335.2 ORX90771.1 - 0.018 15.3 0.0 0.36 11.1 0.0 2.5 1 1 0 1 1 1 0 Ino80 complex subunit 5 AA_permease PF00324.21 ORX90772.1 - 4.1e-137 457.7 38.4 5e-137 457.4 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX90772.1 - 2.3e-43 148.6 41.2 2.8e-43 148.4 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease CIA30 PF08547.12 ORX90773.1 - 2.6e-34 118.6 1.4 3e-34 118.4 1.4 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Flavi_glycop_C PF02832.16 ORX90773.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Brr6_like_C_C PF10104.9 ORX90774.1 - 3.5e-50 169.2 1.6 4.9e-50 168.8 1.6 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Homeodomain PF00046.29 ORX90776.1 - 1.9e-16 59.6 7.1 2.1e-16 59.5 7.1 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX90776.1 - 0.0036 17.2 0.3 0.0069 16.3 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX90776.1 - 0.0062 16.4 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 ORX90776.1 - 0.099 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez S_4TM PF18159.1 ORX90777.1 - 0.056 12.7 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain MSC PF09402.10 ORX90777.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain LEA_2 PF03168.13 ORX90778.1 - 5.7e-06 26.8 0.2 1.2e-05 25.8 0.2 1.6 1 1 1 2 2 2 1 Late embryogenesis abundant protein DUF4307 PF14155.6 ORX90778.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) BTB PF00651.31 ORX90779.1 - 0.034 14.4 0.1 0.41 10.9 0.1 2.1 1 1 0 1 1 1 0 BTB/POZ domain Glyco_trans_4_4 PF13579.6 ORX90779.1 - 0.11 12.9 0.0 16 5.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF4592 PF15262.6 ORX90781.1 - 0.093 13.4 3.2 0.12 13.0 3.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4592) QWRF PF04484.12 ORX90781.1 - 2.4 7.8 10.8 7.7 6.2 10.8 1.6 1 1 0 1 1 1 0 QWRF family 6PF2K PF01591.18 ORX90782.1 - 3.2e-76 255.6 0.8 4.2e-76 255.2 0.8 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORX90782.1 - 4e-38 131.0 0.0 8.3e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORX90782.1 - 1.8e-07 31.4 0.0 3.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORX90782.1 - 3.8e-05 23.3 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 His_Phos_2 PF00328.22 ORX90782.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Stealth_CR3 PF17102.5 ORX90782.1 - 0.28 11.1 1.1 0.62 10.0 0.1 2.1 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 E1-E2_ATPase PF00122.20 ORX90783.1 - 5.1e-36 123.9 2.4 1.4e-35 122.4 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORX90783.1 - 2.8e-20 73.5 0.2 1e-16 61.9 0.2 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX90783.1 - 3.1e-19 69.4 6.1 3.1e-19 69.4 6.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 ORX90783.1 - 3e-12 46.0 0.0 9.3e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX90783.1 - 0.0046 16.7 0.3 4 7.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.24 ORX90783.1 - 0.098 12.5 6.4 2.9 7.7 0.4 2.8 3 0 0 3 3 3 0 Fatty acid desaturase Methyltransf_16 PF10294.9 ORX90784.1 - 7.7e-16 58.3 0.2 1.5e-13 50.9 0.0 2.4 1 1 1 2 2 2 2 Lysine methyltransferase MTS PF05175.14 ORX90784.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX90784.1 - 1.2e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORX90784.1 - 5.5e-06 27.0 0.0 1.5e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX90784.1 - 0.00057 19.7 0.2 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX90784.1 - 0.0086 15.7 0.0 0.019 14.6 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 ORX90784.1 - 0.0093 16.6 0.0 0.024 15.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX90784.1 - 0.023 15.4 0.1 0.065 14.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORX90784.1 - 0.03 14.1 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Enamelin PF15362.6 ORX90784.1 - 0.083 11.2 0.3 0.12 10.7 0.3 1.1 1 0 0 1 1 1 0 Enamelin Methyltransf_23 PF13489.6 ORX90784.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CutA1 PF03091.15 ORX90785.1 - 1.1e-38 131.1 0.3 1.2e-38 130.9 0.3 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Pox_vIL-18BP PF05566.12 ORX90785.1 - 0.045 14.0 0.1 0.057 13.6 0.1 1.4 1 1 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein TMV_coat PF00721.21 ORX90785.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) Pkinase PF00069.25 ORX90786.1 - 1.8e-33 116.1 0.2 6.7e-33 114.2 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90786.1 - 6.8e-15 55.0 0.1 2e-14 53.5 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX90786.1 - 0.0013 18.1 0.1 0.0051 16.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORX90786.1 - 0.0035 17.3 0.1 0.018 14.9 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX90786.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX90786.1 - 0.067 12.1 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PIP49_C PF12260.8 ORX90786.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 GLTSCR1 PF15249.6 ORX90787.1 - 8e-18 64.8 0.1 8e-18 64.8 0.1 1.9 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein Hamartin PF04388.12 ORX90787.1 - 0.0022 16.8 14.5 0.0025 16.6 14.5 1.2 1 0 0 1 1 1 1 Hamartin protein Med3 PF11593.8 ORX90787.1 - 0.17 11.0 17.8 0.24 10.6 17.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 ORX90787.1 - 0.44 10.5 21.5 0.53 10.2 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cation_ATPase_C PF00689.21 ORX90788.1 - 1e-12 48.1 13.8 3e-12 46.6 13.8 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORX90788.1 - 0.055 13.7 0.0 27 4.9 0.0 3.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX90788.1 - 0.067 12.7 0.0 0.067 12.7 0.0 4.3 6 1 0 6 6 6 0 E1-E2 ATPase 2-oxoacid_dh PF00198.23 ORX90789.1 - 5.5e-84 281.2 0.0 7.5e-84 280.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORX90789.1 - 1.9e-16 59.7 0.2 3.5e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORX90789.1 - 1.4e-15 57.3 0.0 3.7e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain DUF1414 PF07208.11 ORX90789.1 - 0.083 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) DUF3614 PF12267.8 ORX90789.1 - 1.9 8.9 5.6 1.1 9.7 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3614) WD40 PF00400.32 ORX90790.1 - 2.1e-20 72.6 25.2 0.00011 22.9 0.2 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90790.1 - 1.7e-17 63.5 4.3 1.1e-06 28.9 0.1 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX90790.1 - 3.3e-08 32.9 0.2 0.00012 21.1 0.1 3.6 1 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORX90790.1 - 6.3e-06 26.2 0.5 0.12 12.2 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ORX90790.1 - 0.0074 15.6 0.1 2.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 ORX90790.1 - 0.04 13.7 0.1 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Phage_G PF02306.15 ORX90790.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) ArsC PF03960.15 ORX90791.1 - 8.8e-07 28.9 0.2 1.2e-06 28.4 0.2 1.6 1 1 0 1 1 1 1 ArsC family Mg_trans_NIPA PF05653.14 ORX90792.1 - 2.5e-19 69.5 19.2 5.4e-12 45.4 5.1 2.7 3 0 0 3 3 3 2 Magnesium transporter NIPA EamA PF00892.20 ORX90792.1 - 1.8e-06 28.2 5.6 1.8e-06 28.2 5.6 3.0 4 0 0 4 4 4 1 EamA-like transporter family TMEM234 PF10639.9 ORX90792.1 - 0.00088 19.3 0.5 0.00088 19.3 0.5 2.6 3 0 0 3 3 3 1 Putative transmembrane family 234 DUF4050 PF13259.6 ORX90792.1 - 0.053 13.8 1.7 0.32 11.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Neurensin PF14927.6 ORX90792.1 - 0.26 11.0 2.2 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 Neurensin SieB PF14163.6 ORX90792.1 - 1.8 8.1 0.0 1.8 8.1 0.0 3.1 3 0 0 3 3 3 0 Super-infection exclusion protein B FAM72 PF14976.6 ORX90793.1 - 4.7e-46 156.5 7.1 5.2e-46 156.4 7.1 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORX90793.1 - 0.0055 16.9 7.9 0.0077 16.4 7.9 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Beach PF02138.18 ORX90794.1 - 8.5e-42 143.4 0.3 2e-41 142.2 0.3 1.6 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 ORX90794.1 - 7.9e-12 45.5 9.8 0.00056 20.7 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90794.1 - 2.2e-09 37.5 0.1 0.004 17.4 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 ORX90794.1 - 2.7e-08 33.5 0.0 9e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain PQQ_2 PF13360.6 ORX90794.1 - 1.9e-05 24.4 0.1 3.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 PQQ-like domain NUP214 PF16755.5 ORX90794.1 - 0.004 16.4 0.4 0.012 14.9 0.4 1.7 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 C_Hendra PF16821.5 ORX90794.1 - 0.0079 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 C protein from hendra and measles viruses DUF1475 PF07343.11 ORX90794.1 - 0.021 14.7 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) WD40_like PF17005.5 ORX90794.1 - 0.029 13.7 10.0 0.0076 15.6 2.3 3.3 3 1 1 4 4 4 0 WD40-like domain Kinesin PF00225.23 ORX90795.1 - 9.3e-91 304.2 0.0 1.1e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX90795.1 - 4e-14 52.8 0.0 6.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 ORX90795.1 - 0.036 13.6 0.0 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4556 PF15094.6 ORX90795.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) LSM PF01423.22 ORX90796.1 - 5e-20 71.0 0.1 5.6e-20 70.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX90796.1 - 1.1e-05 25.4 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORX90796.1 - 0.022 14.8 0.0 0.033 14.3 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Aa_trans PF01490.18 ORX90797.1 - 6.2e-63 212.9 32.0 7.1e-63 212.7 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 ORX90798.1 - 1.1e-52 179.1 31.7 1.3e-52 178.9 31.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX90798.1 - 1.1e-05 24.5 18.2 1.1e-05 24.5 18.2 3.6 2 2 0 2 2 2 1 Spore germination protein TMEM174 PF15029.6 ORX90798.1 - 0.16 11.7 0.3 0.32 10.7 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 VIT1 PF01988.19 ORX90798.1 - 2.2 8.1 8.2 0.31 10.9 0.8 2.6 2 1 0 2 2 2 0 VIT family NAD_binding_10 PF13460.6 ORX90799.1 - 2e-20 73.5 0.0 2.7e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX90799.1 - 1e-15 57.9 0.8 3.5e-15 56.2 0.8 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORX90799.1 - 2.4e-06 27.2 0.6 3.2e-05 23.5 0.1 2.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORX90799.1 - 7.3e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Shikimate_DH PF01488.20 ORX90799.1 - 1.8e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ORX90799.1 - 6.3e-05 23.2 0.1 0.00013 22.2 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 ORX90799.1 - 0.0004 20.9 0.1 0.0019 18.7 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 ORX90799.1 - 0.00043 19.4 0.1 0.0066 15.5 0.2 2.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 ORX90799.1 - 0.00083 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 ORX90799.1 - 0.0037 17.7 0.2 0.0073 16.7 0.2 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ORX90799.1 - 0.0048 16.1 0.8 0.05 12.7 0.2 2.3 2 1 0 3 3 3 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 ORX90799.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 ORX90799.1 - 0.015 14.4 0.2 0.16 11.0 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORX90799.1 - 0.039 13.4 0.5 0.061 12.7 0.2 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 ORX90799.1 - 0.067 13.6 0.0 0.093 13.2 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ORX90799.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORX90799.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ORX90799.1 - 0.13 12.4 0.3 0.47 10.5 0.2 1.8 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 ORX90799.1 - 0.13 11.4 0.2 0.4 9.8 0.1 1.7 2 0 0 2 2 2 0 Male sterility protein Lipase_GDSL_2 PF13472.6 ORX90801.1 - 2e-10 41.4 0.1 3.5e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORX90801.1 - 7.7e-08 32.6 0.2 1.2e-07 31.9 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBAH PF02275.18 ORX90803.1 - 0.027 14.1 0.1 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family FlaG PF03646.15 ORX90804.1 - 0.29 11.3 0.2 0.29 11.3 0.2 1.8 2 0 0 2 2 2 0 FlaG protein SNF2_N PF00176.23 ORX90805.1 - 8.2e-29 100.4 0.1 1.3e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORX90805.1 - 0.0017 18.4 0.1 0.003 17.6 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Kelch_5 PF13854.6 ORX90805.1 - 0.19 11.7 2.6 3.5 7.7 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 ORX90805.1 - 1.6 9.1 3.8 63 4.0 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain NicO PF03824.16 ORX90807.1 - 1.8e-17 63.6 1.7 1.8e-17 63.6 1.7 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein Phage_holin_5_2 PF16079.5 ORX90807.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V C2 PF00168.30 ORX90808.1 - 1.5e-92 304.7 4.8 2.4e-23 82.4 0.4 5.3 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 ORX90808.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.3 1 1 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 ORX90808.1 - 0.27 11.0 2.8 4.2 7.1 0.0 3.5 3 1 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 ORX90809.1 - 6.2e-19 68.2 0.0 6.7e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 C2 domain PP2C PF00481.21 ORX90810.1 - 1.7e-36 126.2 0.0 2.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORX90810.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Exo_endo_phos PF03372.23 ORX90811.1 - 4.1e-15 55.9 0.0 6.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Oxidored_q4 PF00507.19 ORX90811.1 - 0.25 11.5 3.7 0.48 10.6 3.7 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 SAM_Exu PF18609.1 ORX90811.1 - 0.26 11.4 1.3 4.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Exuperantia SAM-like domain DUF4133 PF13571.6 ORX90811.1 - 5.3 7.4 6.5 11 6.4 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Ribosomal_S28e PF01200.18 ORX90812.1 - 1.5e-33 114.5 1.2 1.8e-33 114.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORX90812.1 - 0.044 14.1 0.1 0.048 14.0 0.1 1.2 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORX90812.1 - 0.063 13.3 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Pkinase PF00069.25 ORX90813.1 - 1.4e-73 247.5 0.0 2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90813.1 - 8.5e-45 153.0 0.2 3.3e-44 151.1 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX90813.1 - 2.5e-22 79.0 0.0 5.6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 ORX90813.1 - 3.3e-07 29.9 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX90813.1 - 9.9e-07 27.9 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX90813.1 - 0.00017 20.6 2.0 0.0027 16.7 2.0 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX90813.1 - 0.00063 19.1 0.8 0.0087 15.4 0.1 2.1 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX90813.1 - 0.0029 17.6 0.0 0.24 11.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family UNC-93 PF05978.16 ORX90815.1 - 2.6e-12 46.7 3.9 2.6e-12 46.7 3.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90815.1 - 4.9e-10 38.9 31.2 4.9e-10 38.9 31.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90816.1 - 0.002 17.9 0.3 0.002 17.9 0.3 2.6 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 UNC-93 PF05978.16 ORX90817.1 - 6.7e-07 29.1 2.6 1.4e-06 28.1 0.9 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90817.1 - 0.078 11.9 37.1 0.036 13.0 30.3 2.8 1 1 1 2 2 2 0 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90818.1 - 2.7e-12 46.7 3.9 2.7e-12 46.7 3.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90818.1 - 1.4e-10 40.7 29.3 1.4e-10 40.7 29.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 ORX90818.1 - 0.032 13.2 6.8 0.022 13.8 1.0 2.6 3 0 0 3 3 3 0 PUCC protein MFS_1 PF07690.16 ORX90819.1 - 9e-08 31.4 24.2 9e-08 31.4 24.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90819.1 - 2e-06 27.6 1.0 2e-06 27.6 1.0 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORX90819.1 - 0.027 13.5 6.2 0.026 13.5 1.3 2.6 3 0 0 3 3 3 0 PUCC protein UNC-93 PF05978.16 ORX90820.1 - 2.7e-12 46.7 3.9 2.7e-12 46.7 3.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90820.1 - 1.6e-10 40.5 29.5 1.6e-10 40.5 29.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 ORX90820.1 - 0.032 13.2 6.8 0.022 13.8 1.0 2.6 3 0 0 3 3 3 0 PUCC protein UNC-93 PF05978.16 ORX90821.1 - 6.1e-13 48.8 3.9 2.4e-12 46.9 3.9 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90821.1 - 4.7e-07 29.1 32.8 3.9e-06 26.0 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 ORX90821.1 - 0.022 13.8 6.4 0.021 13.9 1.0 2.6 3 0 0 3 3 3 0 PUCC protein UNC-93 PF05978.16 ORX90822.1 - 2.7e-12 46.7 3.9 2.7e-12 46.7 3.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90822.1 - 1.4e-10 40.7 29.3 1.4e-10 40.7 29.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 ORX90822.1 - 0.032 13.2 6.8 0.022 13.8 1.0 2.6 3 0 0 3 3 3 0 PUCC protein UNC-93 PF05978.16 ORX90823.1 - 2.7e-12 46.7 3.9 2.7e-12 46.7 3.9 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90823.1 - 1.4e-10 40.7 29.3 1.4e-10 40.7 29.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 ORX90823.1 - 0.032 13.2 6.8 0.022 13.8 1.0 2.6 3 0 0 3 3 3 0 PUCC protein UNC-93 PF05978.16 ORX90824.1 - 2.7e-12 46.7 3.9 2.7e-12 46.7 3.9 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX90824.1 - 1.7e-10 40.4 29.5 1.7e-10 40.4 29.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 ORX90824.1 - 0.016 14.2 6.2 0.022 13.8 1.0 2.8 3 0 0 3 3 3 0 PUCC protein MFS_1 PF07690.16 ORX90825.1 - 7e-14 51.5 24.6 9.6e-14 51.1 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90825.1 - 2e-12 47.1 4.8 2e-12 47.1 4.8 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORX90825.1 - 0.017 14.1 4.6 0.018 14.1 0.8 2.4 2 0 0 2 2 2 0 PUCC protein LapA_dom PF06305.11 ORX90825.1 - 0.79 9.6 3.1 5.9 6.8 0.1 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 ORX90826.1 - 7e-14 51.5 24.6 9.6e-14 51.1 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX90826.1 - 2e-12 47.1 4.8 2e-12 47.1 4.8 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORX90826.1 - 0.017 14.1 4.6 0.018 14.1 0.8 2.4 2 0 0 2 2 2 0 PUCC protein LapA_dom PF06305.11 ORX90826.1 - 0.79 9.6 3.1 5.9 6.8 0.1 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_S11 PF00411.19 ORX90827.1 - 1.2e-47 160.9 1.4 1.5e-47 160.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pterin_4a PF01329.19 ORX90828.1 - 1.7e-29 101.8 0.4 1.8e-29 101.7 0.4 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Ribosomal_S8e PF01201.22 ORX90829.1 - 1.4e-55 187.2 2.2 1.8e-55 186.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-C2H2 PF00096.26 ORX90831.1 - 6.9e-15 54.6 9.6 3.1e-07 30.5 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX90831.1 - 5.6e-10 39.2 8.7 0.00015 22.3 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX90831.1 - 1.3e-06 28.6 19.1 4.2e-05 23.8 5.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX90831.1 - 0.00022 21.4 0.5 0.15 12.4 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX90831.1 - 0.00044 20.8 1.9 0.046 14.3 0.1 2.0 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORX90831.1 - 0.0011 19.3 0.3 1.7 9.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORX90831.1 - 0.0015 18.3 8.1 0.089 12.6 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 ORX90831.1 - 0.0023 18.1 1.3 0.0039 17.3 1.3 1.4 1 1 0 1 1 1 1 Aberrant zinc-finger zf-LYAR PF08790.11 ORX90831.1 - 0.0036 17.2 0.2 0.65 10.0 0.0 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.18 ORX90831.1 - 0.03 15.0 3.6 0.24 12.1 3.2 2.0 1 1 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_6 PF13912.6 ORX90831.1 - 0.13 12.3 7.3 0.22 11.5 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 ORX90831.1 - 0.21 11.7 5.0 0.61 10.2 0.4 2.2 2 0 0 2 2 2 0 BED zinc finger Cullin PF00888.22 ORX90832.1 - 2.6e-175 584.6 15.5 3.1e-175 584.3 15.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORX90832.1 - 2.5e-23 81.9 1.3 6.6e-23 80.5 0.8 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Beta_elim_lyase PF01212.21 ORX90833.1 - 9.6e-79 264.7 0.0 1.2e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORX90833.1 - 2e-07 30.6 0.0 3.3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX90833.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORX90833.1 - 0.018 14.3 0.1 0.044 13.1 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2610 PF11020.8 ORX90834.1 - 0.059 13.2 0.0 7.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2610) PCI PF01399.27 ORX90835.1 - 1.1e-09 38.8 0.2 4.3e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 ORX90835.1 - 2.1e-07 30.5 0.2 5.6e-07 29.2 0.2 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DDE_Tnp_1_assoc PF13808.6 ORX90835.1 - 0.025 14.6 0.2 0.37 10.9 0.0 2.8 4 0 0 4 4 4 0 DDE_Tnp_1-associated MOZART1 PF12554.8 ORX90836.1 - 4.8e-24 83.9 0.2 5.6e-24 83.7 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.19 ORX90836.1 - 0.05 13.8 0.1 0.077 13.2 0.1 1.4 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain MMR_HSR1 PF01926.23 ORX90837.1 - 9.3e-16 57.9 0.0 2.5e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX90837.1 - 1.3e-06 28.1 0.6 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX90837.1 - 3.1e-05 23.9 0.6 0.00012 22.1 0.6 2.0 1 1 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 ORX90837.1 - 3.3e-05 23.1 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 ORX90837.1 - 0.0013 18.1 0.1 0.0094 15.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 ORX90837.1 - 0.024 14.7 1.9 2 8.5 0.1 3.2 2 1 1 3 3 3 0 Dynamin family DUF1694 PF07997.11 ORX90837.1 - 0.026 14.6 0.6 0.057 13.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Ras PF00071.22 ORX90837.1 - 0.035 13.7 1.1 2 8.0 0.2 2.2 2 0 0 2 2 2 0 Ras family Roc PF08477.13 ORX90837.1 - 0.077 13.2 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PAS PF00989.25 ORX90838.1 - 0.013 15.4 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold ERF PF04404.12 ORX90839.1 - 0.12 12.3 2.3 0.44 10.4 3.1 1.5 2 0 0 2 2 2 0 ERF superfamily NOA36 PF06524.12 ORX90839.1 - 0.15 11.3 8.1 0.19 11.0 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 ORX90839.1 - 0.26 10.1 2.0 0.25 10.1 2.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sporozoite_P67 PF05642.11 ORX90839.1 - 0.47 8.5 4.9 0.62 8.1 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PH PF00169.29 ORX90840.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 PH domain Hydrolase PF00702.26 ORX90841.1 - 1.2e-08 35.5 0.0 3.2e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX90841.1 - 0.00014 22.0 0.1 0.00045 20.3 0.1 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX90841.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L2_C PF03947.18 ORX90842.1 - 3.7e-49 166.1 3.1 5.8e-49 165.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORX90842.1 - 4e-16 58.7 0.0 1.4e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain TAF4 PF05236.14 ORX90843.1 - 3.1e-37 128.8 0.2 1e-36 127.2 0.2 1.9 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family RST PF12174.8 ORX90843.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Epimerase PF01370.21 ORX90844.1 - 4.5e-22 78.7 0.0 6.5e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX90844.1 - 1.5e-16 60.2 0.0 1.9e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX90844.1 - 1e-13 51.1 0.3 1.2e-11 44.3 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORX90844.1 - 1.5e-12 47.5 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORX90844.1 - 1.5e-11 44.5 0.0 2.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX90844.1 - 2.2e-08 34.0 0.0 8.8e-08 32.0 0.0 1.8 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORX90844.1 - 6.4e-06 25.5 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORX90844.1 - 1.1e-05 25.4 0.0 4.3e-05 23.5 0.1 1.9 2 1 0 2 2 2 1 KR domain RSN1_7TM PF02714.15 ORX90846.1 - 3.8e-73 246.2 26.2 5.7e-73 245.6 26.2 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX90846.1 - 2.3e-34 119.1 0.0 3.2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORX90846.1 - 2.2e-28 99.0 0.1 2.2e-28 99.0 0.1 2.9 4 2 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF2284 PF10050.9 ORX90850.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) SNF2_N PF00176.23 ORX90851.1 - 1.3e-09 37.3 0.1 2.2e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Kelch_6 PF13964.6 ORX90851.1 - 0.015 15.6 0.2 14 6.1 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 ORX90851.1 - 0.024 14.6 0.2 5.1 7.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 ORX90851.1 - 0.038 14.0 0.0 10 6.3 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 ORX90851.1 - 0.15 12.3 3.2 13 6.2 0.0 3.9 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_4 PF13418.6 ORX90851.1 - 0.19 11.8 0.1 14 5.8 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Sun2_CC2 PF18580.1 ORX90852.1 - 3 8.1 4.9 3.1 8.1 0.8 2.2 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 CBAH PF02275.18 ORX90853.1 - 0.024 14.3 0.2 0.031 13.9 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family MFS_1 PF07690.16 ORX90854.1 - 2.6e-53 181.2 46.1 2.6e-53 181.2 46.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX90854.1 - 3.1e-16 59.3 9.4 3.1e-16 59.3 9.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX90854.1 - 1.1e-14 53.8 24.7 2e-14 52.9 24.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HP_OMP PF01856.17 ORX90854.1 - 0.09 12.8 0.2 0.28 11.3 0.2 1.7 1 1 0 1 1 1 0 Helicobacter outer membrane protein DUF2527 PF10736.9 ORX90854.1 - 0.15 11.9 0.5 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) MFS_1 PF07690.16 ORX90855.1 - 4.6e-54 183.7 43.8 4.6e-54 183.7 43.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX90855.1 - 3.3e-17 62.2 24.6 5.2e-17 61.5 24.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX90855.1 - 5.6e-15 55.1 12.9 5.6e-15 55.1 12.9 2.9 2 1 2 4 4 4 1 Sugar (and other) transporter Oxidored_FMN PF00724.20 ORX90856.1 - 4.1e-75 253.2 0.0 4.8e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ORX90856.1 - 0.018 14.1 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Thaumatin PF00314.17 ORX90857.1 - 1.6e-68 230.6 12.8 1.7e-68 230.4 12.8 1.0 1 0 0 1 1 1 1 Thaumatin family SH3_1 PF00018.28 ORX90858.1 - 3.6e-13 48.9 0.0 7.8e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX90858.1 - 1.1e-11 44.4 0.5 2.8e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORX90858.1 - 4.9e-10 38.9 0.0 9.8e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 ORX90858.1 - 1e-09 38.5 0.7 2.4e-09 37.3 0.7 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Chromo_shadow PF01393.19 ORX90859.1 - 1.1e-17 63.9 1.8 1.1e-14 54.2 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 ORX90859.1 - 1.8e-16 59.8 4.9 1.8e-16 59.8 4.9 2.6 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 ORX90859.1 - 0.087 13.0 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 FKBP_C PF00254.28 ORX90860.1 - 4.3e-33 113.5 0.0 5.5e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ATP-synt_10 PF05176.14 ORX90861.1 - 2.3e-48 164.7 0.1 2.7e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 ATP10 protein ANTH PF07651.16 ORX90862.1 - 4.6e-55 186.6 1.9 6e-55 186.2 1.9 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ORX90862.1 - 1.7e-07 31.3 0.0 4.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 ENTH domain FHA PF00498.26 ORX90863.1 - 6.9e-09 35.9 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 ORX90863.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain FERM_f0 PF16511.5 ORX90864.1 - 0.068 13.5 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Ceramidase PF05875.12 ORX90865.1 - 1.4e-53 182.0 13.0 1.6e-53 181.9 13.0 1.0 1 0 0 1 1 1 1 Ceramidase DUF4231 PF14015.6 ORX90865.1 - 0.82 10.2 2.9 0.61 10.6 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) CRAL_TRIO PF00650.20 ORX90866.1 - 1.1e-38 132.5 0.0 1.7e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX90866.1 - 6.2e-12 45.5 0.5 2.1e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORX90866.1 - 3.6e-07 30.4 0.0 5.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain BTD PF09270.10 ORX90867.1 - 7.2e-27 94.5 0.0 1.2e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 ORX90867.1 - 5.1e-26 92.1 1.9 1.7e-23 83.9 1.9 2.3 1 1 0 1 1 1 1 LAG1, DNA binding CENP-M PF11111.8 ORX90868.1 - 2.4e-21 75.7 0.0 2.6e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) KH_6 PF15985.5 ORX90869.1 - 2.3e-18 66.3 0.0 4.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 ORX90869.1 - 4.2e-11 42.6 0.0 9.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Aminotran_1_2 PF00155.21 ORX90870.1 - 3.3e-38 131.8 0.0 4.1e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX90870.1 - 0.0075 14.8 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 ORX90871.1 - 6.8e-78 261.7 0.0 1e-77 261.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90871.1 - 1.1e-36 126.5 0.0 1.6e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX90871.1 - 1.4e-06 27.9 0.2 3.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX90871.1 - 0.00022 20.3 2.2 0.0015 17.6 2.2 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX90871.1 - 0.0026 17.1 0.2 0.0026 17.1 0.2 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORX90871.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Proteasome PF00227.26 ORX90872.1 - 1.7e-61 207.0 0.1 2.5e-61 206.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORX90872.1 - 6.4e-11 41.7 0.1 2.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SRA1 PF07304.11 ORX90873.1 - 1.3e-11 44.5 0.0 1.3e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 ORX90873.1 - 2.5e-09 37.6 8.6 0.16 12.9 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Prp18 PF02840.15 ORX90873.1 - 0.00011 22.3 0.1 0.00028 20.9 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain Helicase_PWI PF18149.1 ORX90873.1 - 0.063 13.5 2.9 0.06 13.5 0.6 2.0 2 0 0 2 2 2 0 N-terminal helicase PWI domain TPR_19 PF14559.6 ORX90873.1 - 0.1 13.1 0.2 1.2 9.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec16_C PF12931.7 ORX90873.1 - 0.1 12.2 0.3 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 TPT PF03151.16 ORX90874.1 - 7.5e-25 87.9 28.6 9.3e-25 87.6 28.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORX90874.1 - 5e-08 33.2 32.3 1.4e-07 31.7 13.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF5090 PF17009.5 ORX90874.1 - 5.4 6.9 17.9 0.043 13.8 4.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) RNB PF00773.19 ORX90875.1 - 1.9e-101 339.6 0.4 4.7e-101 338.4 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 ORX90875.1 - 2.4e-26 91.6 0.0 5.3e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORX90875.1 - 5.4e-20 71.5 0.0 2.1e-19 69.6 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_S1 PF17215.3 ORX90875.1 - 6.5e-06 26.0 0.0 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 ORX90875.1 - 3.5e-05 23.9 0.0 0.00035 20.7 0.0 2.5 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 ORX90875.1 - 0.0002 21.1 0.0 0.00056 19.7 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 ORX90875.1 - 0.04 13.6 0.2 0.51 10.1 0.0 2.7 3 0 0 3 3 3 0 Ribonuclease B OB domain Mitochondr_Som1 PF11093.8 ORX90876.1 - 4e-11 42.7 0.9 6.1e-11 42.2 0.8 1.3 1 1 0 1 1 1 1 Mitochondrial export protein Som1 DUF1744 PF08490.12 ORX90877.1 - 4.5e-142 473.3 0.0 7e-142 472.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 ORX90877.1 - 6e-80 268.9 2.7 6e-80 268.9 2.7 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORX90877.1 - 4.9e-14 51.9 1.1 5.2e-12 45.2 0.7 3.5 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 ORX90877.1 - 3.1e-12 46.6 0.1 1e-11 44.9 0.1 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ORX90877.1 - 3.5e-06 27.1 0.1 1.7e-05 24.9 0.1 2.2 1 0 0 1 1 1 1 RNase_H superfamily APP_N PF02177.16 ORX90877.1 - 0.043 14.2 1.3 0.12 12.7 0.3 2.4 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding eIF2A PF08662.11 ORX90879.1 - 2.8e-36 125.2 1.7 7.3e-32 110.8 0.8 4.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORX90879.1 - 5.1e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PilJ PF13675.6 ORX90879.1 - 0.13 12.2 2.9 0.28 11.2 2.9 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cyclin_N PF00134.23 ORX90880.1 - 1.4e-45 154.1 0.2 1.2e-43 147.9 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX90880.1 - 1e-37 128.9 1.3 2e-37 127.9 1.3 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain RBB1NT PF08169.11 ORX90881.1 - 1.5e-08 34.6 0.0 6.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 RBB1NT (NUC162) domain PWWP PF00855.17 ORX90881.1 - 5.9e-08 33.0 0.7 1.4e-07 31.8 0.1 1.9 2 0 0 2 2 2 1 PWWP domain ORC6 PF05460.13 ORX90881.1 - 0.84 8.8 8.4 1.2 8.4 8.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Arrestin_C PF02752.22 ORX90882.1 - 5.9e-07 30.0 0.0 7.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX90882.1 - 0.0077 16.3 1.6 0.024 14.7 0.1 2.4 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Ion_trans PF00520.31 ORX90883.1 - 5.4e-59 199.4 33.1 2.6e-45 154.6 15.4 2.2 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 ORX90883.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated STAS PF01740.21 ORX90884.1 - 3.2e-12 46.1 0.0 8.8e-12 44.7 0.0 1.7 1 1 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORX90884.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 STAS domain zf-CCCH_4 PF18044.1 ORX90885.1 - 2e-11 43.4 4.0 3.3e-11 42.7 4.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 ORX90885.1 - 4e-11 42.7 4.0 1.1e-10 41.4 4.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 ORX90885.1 - 9e-08 31.9 5.4 1.4e-07 31.2 5.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX90885.1 - 9.8e-08 31.8 6.2 1.6e-07 31.1 6.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 ORX90885.1 - 0.00061 20.2 5.0 0.0012 19.3 5.0 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORX90885.1 - 0.0076 16.9 0.3 0.02 15.6 0.3 1.7 1 0 0 1 1 1 1 Torus domain Homeodomain PF00046.29 ORX90886.1 - 1.2e-10 41.1 0.1 1.8e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX90886.1 - 5.2e-06 26.3 0.0 9.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain MerR_1 PF13411.6 ORX90886.1 - 0.0062 16.6 0.2 0.13 12.4 0.2 2.2 1 1 1 2 2 2 1 MerR HTH family regulatory protein Chitin_synth_2 PF03142.15 ORX90887.1 - 4.7e-249 827.4 1.1 6.5e-249 826.9 1.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORX90887.1 - 8.4e-109 364.7 0.4 1.5e-108 363.9 0.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) NAPRTase PF04095.16 ORX90887.1 - 6.6e-39 134.0 0.0 1.1e-38 133.2 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DEK_C PF08766.11 ORX90887.1 - 3.8e-20 71.6 0.1 1.6e-19 69.6 0.2 2.0 2 0 0 2 2 2 1 DEK C terminal domain DUF5598 PF18127.1 ORX90887.1 - 3e-13 50.0 0.1 1.2e-12 48.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) Glyco_trans_2_3 PF13632.6 ORX90887.1 - 1.6e-11 44.5 2.7 4.3e-11 43.1 2.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX90887.1 - 1.2e-10 41.7 0.0 6.9e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORX90887.1 - 3.6e-07 30.2 0.5 0.019 15.1 0.1 4.1 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORX90887.1 - 6.2e-06 26.1 0.0 0.0063 16.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 ORX90887.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Glyco_transf_21 PF13506.6 ORX90887.1 - 0.007 15.9 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Sld5 PF05916.11 ORX90887.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 GINS complex protein PhageMin_Tail PF10145.9 ORX90887.1 - 0.46 10.3 2.1 0.7 9.7 0.1 2.3 3 0 0 3 3 3 0 Phage-related minor tail protein SNF2_N PF00176.23 ORX90888.1 - 7.8e-57 192.6 0.5 1.3e-56 191.9 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX90888.1 - 2e-18 66.8 0.0 5.4e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORX90888.1 - 1.6e-13 50.5 1.6 5.2e-13 48.8 1.6 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 ORX90888.1 - 3.1e-11 43.0 2.1 0.00012 21.9 0.1 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 ORX90888.1 - 2.1e-07 31.1 0.0 5.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORX90888.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1087 PF06465.13 ORX90888.1 - 0.00027 20.9 0.8 0.0011 19.0 0.6 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) PHD_4 PF16866.5 ORX90888.1 - 0.0031 17.6 3.8 0.0068 16.5 2.5 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 ORX90888.1 - 0.014 15.3 1.7 0.014 15.3 1.7 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 ORX90888.1 - 0.058 13.0 0.3 0.058 13.0 0.3 2.5 3 0 0 3 3 3 0 PHD-finger AAA_22 PF13401.6 ORX90888.1 - 0.094 13.0 0.1 0.65 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain FliS PF02561.14 ORX90888.1 - 0.096 13.0 0.6 0.32 11.3 0.6 1.8 1 0 0 1 1 1 0 Flagellar protein FliS Cyclin PF08613.11 ORX90889.1 - 2.6e-06 27.9 0.0 0.029 14.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 ORX90889.1 - 0.00053 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chitin_synth_2 PF03142.15 ORX90890.1 - 2.9e-248 824.8 0.8 3.9e-248 824.4 0.8 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORX90890.1 - 2e-142 475.8 0.2 2.7e-142 475.3 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORX90890.1 - 7.9e-19 67.3 0.0 4.3e-18 65.0 0.1 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORX90890.1 - 9.1e-13 48.6 0.0 3.1e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX90890.1 - 1.4e-12 48.0 4.2 1.4e-12 48.0 4.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 ORX90890.1 - 5.9e-08 32.7 2.3 6e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORX90890.1 - 6.2e-06 26.1 0.0 0.0051 16.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX90890.1 - 0.0031 17.0 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.6 ORX90890.1 - 0.059 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX90890.1 - 0.18 12.1 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sulfate_transp PF00916.20 ORX90891.1 - 1.7e-85 287.1 28.2 1.3e-83 280.9 28.2 2.1 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX90891.1 - 1.1e-12 47.6 0.0 8.7e-12 44.7 0.0 2.3 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORX90891.1 - 0.0056 17.1 7.3 0.0056 17.1 7.3 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily Y_phosphatase3 PF13350.6 ORX90892.1 - 4.7e-48 164.2 0.2 2.5e-47 161.8 0.2 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ORX90892.1 - 1e-07 31.7 1.0 8.4e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 ORX90892.1 - 0.00064 18.8 0.1 0.0011 18.0 0.1 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 ORX90892.1 - 0.0007 19.2 0.1 0.0014 18.3 0.1 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORX90892.1 - 0.0012 18.7 0.9 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain SMODS PF18144.1 ORX90892.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain PTPlike_phytase PF14566.6 ORX90892.1 - 0.29 11.2 3.1 2.6 8.2 0.0 2.8 3 1 0 3 3 3 0 Inositol hexakisphosphate TRAM_LAG1_CLN8 PF03798.16 ORX90893.1 - 1.1e-39 136.3 25.2 1.1e-39 136.3 25.2 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORX90893.1 - 8.3e-20 70.2 0.2 8.3e-20 70.2 0.2 2.2 2 0 0 2 2 2 1 TRAM1-like protein Fungal_trans PF04082.18 ORX90894.1 - 8.2e-23 80.8 1.1 1.8e-22 79.6 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX90894.1 - 2.5e-13 49.9 12.5 5.2e-13 48.9 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Terpene_synth_C PF03936.16 ORX90895.1 - 9.2e-05 21.9 0.6 0.00027 20.4 0.0 2.1 3 0 0 3 3 3 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 ORX90895.1 - 0.0038 16.1 0.1 0.006 15.5 0.1 1.4 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) RRF_GI PF12614.8 ORX90895.1 - 0.026 14.7 0.2 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Ribosome recycling factor CAP59_mtransfer PF11735.8 ORX90897.1 - 2.5e-77 259.8 0.0 3e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1700 PF08006.11 ORX90897.1 - 0.012 15.2 7.1 0.021 14.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ABC_export PF16962.5 ORX90897.1 - 0.57 8.6 7.9 0.78 8.1 7.9 1.1 1 0 0 1 1 1 0 Putative ABC exporter DUF2070 PF09843.9 ORX90897.1 - 2 6.6 5.5 2.4 6.4 5.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ndc1_Nup PF09531.10 ORX90897.1 - 5.9 5.5 8.0 8.7 4.9 8.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAP59_mtransfer PF11735.8 ORX90898.1 - 2e-77 260.2 0.0 2.5e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1700 PF08006.11 ORX90898.1 - 0.015 14.8 7.1 0.027 14.0 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ABC_export PF16962.5 ORX90898.1 - 0.71 8.2 7.9 0.99 7.8 7.9 1.1 1 0 0 1 1 1 0 Putative ABC exporter DUF2070 PF09843.9 ORX90898.1 - 3.2 5.9 5.9 4.1 5.6 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RTC4 PF14474.6 ORX90899.1 - 6.4e-05 23.1 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DUF4537 PF15057.6 ORX90899.1 - 0.002 18.2 0.0 0.0058 16.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Pkinase PF00069.25 ORX90900.1 - 4.7e-29 101.5 0.0 5.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90900.1 - 1.1e-16 61.0 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX90900.1 - 2.1e-09 36.7 0.1 2.5e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX90900.1 - 0.0012 18.8 0.2 0.0093 15.9 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORX90900.1 - 0.018 14.0 0.1 0.027 13.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 ORX90900.1 - 0.057 12.8 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 ORX90900.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC1 family zf-NOSIP PF15906.5 ORX90901.1 - 3e-14 52.9 0.3 6.5e-14 51.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 ORX90901.1 - 3.8e-07 29.9 22.3 0.00019 21.3 12.7 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX90901.1 - 4.3e-07 30.2 19.8 2.8e-06 27.6 10.0 2.3 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.12 ORX90901.1 - 9.2e-07 28.5 5.8 9.2e-07 28.5 5.8 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 ORX90901.1 - 2.5e-06 27.4 16.9 0.0076 16.3 0.9 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 ORX90901.1 - 3.6e-06 26.8 19.6 0.00014 21.8 10.2 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORX90901.1 - 3.6e-05 23.5 21.2 0.00056 19.7 11.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX90901.1 - 9.2e-05 22.2 22.5 0.0022 17.8 11.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORX90901.1 - 0.0003 20.9 20.1 0.027 14.6 10.4 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORX90901.1 - 0.0066 16.3 25.1 0.046 13.6 13.8 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORX90901.1 - 0.025 14.9 7.4 0.025 14.9 7.4 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Nuc_deoxyri_tr3 PF11071.8 ORX90901.1 - 0.1 12.6 0.6 0.17 11.9 0.6 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ zf-RING_10 PF16685.5 ORX90901.1 - 0.29 11.3 18.3 1.3 9.3 11.4 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 ORX90901.1 - 0.43 10.5 13.0 0.046 13.6 8.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADIP PF11559.8 ORX90901.1 - 1.6 8.8 17.0 1.6 8.8 6.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding tRNA_anti-codon PF01336.25 ORX90902.1 - 0.00047 20.1 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PGK PF00162.19 ORX90903.1 - 1.1e-125 419.5 0.4 1.2e-125 419.4 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Yqai PF09466.10 ORX90903.1 - 0.052 13.9 0.1 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Hypothetical protein Yqai GST_C_3 PF14497.6 ORX90904.1 - 4.4e-11 42.8 0.5 1.1e-10 41.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX90904.1 - 2.9e-08 33.9 0.0 7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORX90904.1 - 8.9e-06 26.0 0.0 1.7e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX90904.1 - 0.0035 17.6 0.0 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX90904.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_18 PF00704.28 ORX90905.1 - 4e-14 53.0 5.5 5.4e-14 52.6 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_97 PF10566.9 ORX90905.1 - 0.0085 15.4 0.5 0.015 14.6 0.5 1.5 1 0 0 1 1 1 1 Glycoside hydrolase 97 Phospholip_B PF04916.13 ORX90905.1 - 0.0086 14.7 0.7 0.015 13.9 0.2 1.5 1 1 0 1 1 1 1 Phospholipase B tRNA_anti-like PF12869.7 ORX90905.1 - 0.051 13.2 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 tRNA_anti-like PDEase_I PF00233.19 ORX90906.1 - 6.2e-75 252.0 0.1 7.3e-75 251.8 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 ORX90906.1 - 0.0089 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 HD domain tRNA-synt_2_TM PF16995.5 ORX90906.1 - 0.054 13.2 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase PIP5K PF01504.18 ORX90907.1 - 1.2e-42 146.1 1.1 4.5e-35 121.2 1.7 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ORX90907.1 - 1.2e-29 103.3 0.0 2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 ORX90907.1 - 1e-17 64.0 9.8 1e-17 64.0 9.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 ORX90907.1 - 0.056 13.7 4.6 0.19 11.9 4.6 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 ORX90907.1 - 2.5 8.4 15.2 1.7 9.0 9.2 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 ORX90907.1 - 8.5 6.5 12.1 42 4.3 12.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon Ion_trans PF00520.31 ORX90908.1 - 3e-05 23.4 12.7 3.9e-05 23.0 12.7 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ORX90908.1 - 0.12 11.0 11.7 0.23 10.1 10.3 1.8 1 1 1 2 2 2 0 Polycystin cation channel CitMHS PF03600.16 ORX90908.1 - 0.17 11.1 9.7 0.28 10.3 9.7 1.4 1 1 0 1 1 1 0 Citrate transporter AC_N PF16214.5 ORX90908.1 - 0.53 9.4 9.2 0.63 9.1 9.2 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region MARVEL PF01284.23 ORX90908.1 - 8.8 6.4 12.2 37 4.3 11.2 1.9 1 1 0 1 1 1 0 Membrane-associating domain Pkinase PF00069.25 ORX90909.1 - 4.4e-67 226.2 0.0 5.2e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90909.1 - 4.5e-26 91.7 0.0 6.2e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX90909.1 - 2.7e-05 23.6 0.0 0.00046 19.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORX90909.1 - 0.0011 18.9 0.0 0.0071 16.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORX90909.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 ORX90909.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 ORX90909.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX90909.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 eRF1_2 PF03464.15 ORX90910.1 - 5.8e-45 152.9 0.1 9.5e-45 152.2 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORX90910.1 - 4.3e-38 130.3 0.1 8.9e-38 129.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 ORX90910.1 - 8.7e-21 74.3 0.0 1.9e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 ORX90910.1 - 2.6e-09 37.4 0.0 4.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 ORX90910.1 - 4.3e-09 36.8 0.1 6.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Kinesin PF00225.23 ORX90911.1 - 7e-113 376.9 2.4 8.5e-113 376.6 2.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX90911.1 - 3.4e-28 98.4 0.3 8.3e-28 97.2 0.3 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 ORX90911.1 - 0.41 10.1 2.0 0.42 10.1 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region Porin_3 PF01459.22 ORX90912.1 - 4.6e-82 275.5 1.1 5.2e-82 275.3 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin AAA PF00004.29 ORX90913.1 - 1.6e-44 151.5 0.1 8.2e-44 149.2 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX90913.1 - 1.7e-10 40.5 0.1 4.1e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORX90913.1 - 9e-10 38.4 0.3 6.3e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORX90913.1 - 2.3e-08 34.1 0.1 7e-08 32.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX90913.1 - 3.9e-08 33.9 0.2 3e-05 24.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 ORX90913.1 - 8.1e-08 32.6 0.0 2.6e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORX90913.1 - 2.6e-06 26.8 0.2 6.4e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORX90913.1 - 5.4e-05 23.5 1.1 0.01 16.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 ORX90913.1 - 0.0002 21.4 0.0 0.015 15.3 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORX90913.1 - 0.00028 21.2 0.1 0.00062 20.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 ORX90913.1 - 0.00031 21.3 0.1 0.003 18.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 ORX90913.1 - 0.00042 20.1 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ORX90913.1 - 0.0006 19.8 0.0 0.0028 17.6 0.0 2.1 2 0 0 2 2 2 1 NTPase CENP-F_leu_zip PF10473.9 ORX90913.1 - 0.0016 18.5 1.7 0.0025 17.8 1.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_30 PF13604.6 ORX90913.1 - 0.0019 17.9 0.1 0.0057 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORX90913.1 - 0.0022 17.5 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 ORX90913.1 - 0.0027 17.7 0.0 0.0082 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORX90913.1 - 0.0028 18.0 0.0 0.0066 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 ORX90913.1 - 0.003 17.7 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 ORX90913.1 - 0.0069 15.8 0.0 0.53 9.7 0.0 2.6 3 0 0 3 3 2 1 Bacterial TniB protein AAA_3 PF07726.11 ORX90913.1 - 0.0079 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORX90913.1 - 0.0084 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 ORX90913.1 - 0.013 15.4 1.6 0.3 11.0 0.0 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 ORX90913.1 - 0.017 14.8 0.1 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 ORX90913.1 - 0.02 14.1 0.0 0.058 12.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 ORX90913.1 - 0.02 14.8 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 ORX90913.1 - 0.022 14.5 0.1 0.047 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORX90913.1 - 0.024 14.4 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORX90913.1 - 0.039 13.5 0.4 0.2 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX90913.1 - 0.047 14.0 0.2 0.15 12.4 0.1 1.8 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.18 ORX90913.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein NRBF2 PF08961.10 ORX90913.1 - 0.056 13.1 2.8 0.1 12.2 2.8 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Sigma54_activat PF00158.26 ORX90913.1 - 0.09 12.5 0.1 1.2 8.8 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 ORX90913.1 - 0.096 11.5 0.0 0.18 10.7 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase cobW PF02492.19 ORX90913.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORX90913.1 - 0.15 12.6 0.0 0.83 10.2 0.0 2.3 3 0 0 3 3 2 0 ABC transporter CAP59_mtransfer PF11735.8 ORX90913.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 AAA_29 PF13555.6 ORX90913.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 ORX90913.1 - 0.22 10.8 1.2 0.58 9.5 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 ORX90913.1 - 0.3 11.6 5.4 2.7 8.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain PIG-U PF06728.13 ORX90914.1 - 2.9e-116 388.7 31.7 3.3e-116 388.5 31.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 ORX90914.1 - 0.0081 15.9 12.1 0.0081 15.9 12.1 2.3 2 0 0 2 2 2 1 8TM Microsporidial transmembrane domain Ribosomal_L44 PF00935.19 ORX90915.1 - 3.9e-37 126.6 11.0 5.7e-37 126.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Peptidase_M10 PF00413.24 ORX90916.1 - 0.042 13.7 0.2 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Matrixin Spore_YpjB PF09577.10 ORX90918.1 - 0.2 11.4 0.2 0.28 11.0 0.2 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) PSGP PF07276.11 ORX90918.1 - 1.3 9.6 10.7 8.1 7.1 2.1 2.9 2 0 0 2 2 2 0 Apopolysialoglycoprotein (PSGP) DUF4083 PF13314.6 ORX90919.1 - 0.14 12.1 0.2 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Protocadherin PF08374.11 ORX90919.1 - 0.55 10.2 2.9 0.94 9.4 2.9 1.8 1 1 0 1 1 1 0 Protocadherin CPDase PF07823.11 ORX90925.1 - 0.019 14.6 0.3 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein MGC-24 PF05283.11 ORX90925.1 - 0.028 14.9 10.1 0.036 14.5 10.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SWI-SNF_Ssr4 PF08549.10 ORX90925.1 - 0.033 12.8 0.5 0.035 12.8 0.5 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Taxilin PF09728.9 ORX90926.1 - 3e-79 266.4 50.8 3e-79 266.4 50.8 1.8 2 1 0 2 2 2 1 Myosin-like coiled-coil protein BRE1 PF08647.11 ORX90926.1 - 0.0031 17.5 3.4 0.0031 17.5 3.4 4.8 2 1 2 5 5 5 2 BRE1 E3 ubiquitin ligase LtuB PF17455.2 ORX90926.1 - 0.073 13.7 5.2 1.7 9.3 0.3 3.8 3 0 0 3 3 3 0 Late transcription unit B Virulence_fact PF13769.6 ORX90926.1 - 3.6 7.9 8.8 5.9 7.2 0.4 3.4 2 1 1 3 3 3 0 Virulence factor Arrestin_N PF00339.29 ORX90927.1 - 5.9e-17 62.1 0.0 1.3e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX90927.1 - 2.9e-16 60.1 0.5 8.7e-14 52.1 0.4 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX90927.1 - 0.044 13.5 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Arrestin_N terminal like MFS_1 PF07690.16 ORX90928.1 - 1.2e-29 103.4 35.1 1.2e-29 103.4 35.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX90928.1 - 3.8e-08 32.6 6.0 3.8e-08 32.6 6.0 2.9 1 1 2 3 3 3 2 Sugar (and other) transporter COX4 PF02936.14 ORX90928.1 - 0.49 10.4 1.7 14 5.7 0.1 3.5 4 1 0 4 4 4 0 Cytochrome c oxidase subunit IV PAC2 PF09754.9 ORX90929.1 - 0.0092 16.0 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 PAC2 family Dus PF01207.17 ORX90930.1 - 3.9e-79 266.0 0.0 5.5e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 ORX90930.1 - 0.0006 19.7 0.1 0.0069 16.2 0.0 2.1 1 1 1 2 2 2 1 SOR/SNZ family NMO PF03060.15 ORX90930.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DUF2378 PF09536.10 ORX90930.1 - 0.042 13.7 0.1 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) ThiG PF05690.14 ORX90930.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 ORX90930.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 ORX90930.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF5547 PF17701.1 ORX90930.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5547) PIG-L PF02585.17 ORX90931.1 - 8.2e-26 91.2 0.2 1.1e-25 90.7 0.2 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase TPR_2 PF07719.17 ORX90932.1 - 1.6e-20 71.5 3.1 2.3e-07 30.4 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORX90932.1 - 5.5e-18 64.0 8.2 4.9e-08 32.5 0.0 4.6 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORX90932.1 - 1.2e-16 60.7 7.0 6.8e-08 32.7 0.4 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORX90932.1 - 1.1e-14 53.9 9.6 1.6e-06 27.7 0.1 4.4 2 2 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 ORX90932.1 - 1.2e-14 53.2 6.1 0.0011 19.0 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX90932.1 - 8e-12 44.7 3.2 0.025 14.9 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORX90932.1 - 2.2e-11 44.2 0.1 7.5e-06 26.5 0.0 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX90932.1 - 2e-09 37.8 1.7 0.0014 19.1 0.0 3.6 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX90932.1 - 7.7e-08 31.8 1.1 0.39 10.9 0.1 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORX90932.1 - 9.3e-08 32.2 2.3 0.0047 17.5 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX90932.1 - 8.3e-07 29.3 0.1 0.16 12.9 0.0 4.6 1 1 4 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX90932.1 - 2.3e-06 27.7 1.7 0.00027 21.1 0.3 2.2 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORX90932.1 - 2.5e-05 24.3 0.0 0.091 12.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORX90932.1 - 0.00043 19.6 0.2 0.00068 18.9 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX90932.1 - 0.00078 19.2 3.5 0.066 13.1 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 ORX90932.1 - 0.00092 19.2 9.5 0.052 13.6 0.7 3.3 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 ORX90932.1 - 0.0033 16.4 0.7 0.0084 15.1 0.2 1.6 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 ORX90932.1 - 0.0096 15.9 0.2 0.029 14.3 0.1 1.8 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal DUF3856 PF12968.7 ORX90932.1 - 0.017 15.2 0.6 0.57 10.2 0.6 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 ORX90932.1 - 0.023 15.3 0.0 1.7 9.5 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORX90932.1 - 0.071 13.1 4.4 1.3 9.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF357 PF04010.13 ORX90932.1 - 0.084 13.0 2.1 0.98 9.5 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF357) RabGAP-TBC PF00566.18 ORX90933.1 - 1e-52 178.9 0.1 1.8e-52 178.1 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Xpo1 PF08389.12 ORX90935.1 - 1.1e-19 70.9 2.7 4.7e-16 59.2 0.0 5.5 3 2 1 5 5 5 1 Exportin 1-like protein Importin_rep PF18773.1 ORX90935.1 - 3e-19 68.4 0.2 6.8e-19 67.3 0.2 1.7 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 ORX90935.1 - 6.6e-07 29.3 0.0 3.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Importin 13 repeat IBN_N PF03810.19 ORX90935.1 - 0.00012 21.9 0.5 0.00067 19.5 0.3 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Mannitol_dh_C PF08125.13 ORX90935.1 - 0.049 13.1 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain MRP-S27 PF10037.9 ORX90935.1 - 0.099 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 SapB_2 PF03489.17 ORX90935.1 - 0.14 12.3 0.2 20 5.4 0.1 3.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 Ecl1 PF12855.7 ORX90936.1 - 5.6e-12 47.2 3.0 7.8e-12 46.7 3.0 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PHF5 PF03660.14 ORX90936.1 - 0.032 14.4 0.2 0.041 14.1 0.2 1.2 1 0 0 1 1 1 0 PHF5-like protein DUF2116 PF09889.9 ORX90936.1 - 0.039 13.9 0.6 0.072 13.1 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SKI PF01202.22 ORX90938.1 - 2e-10 41.0 0.0 2.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ORX90938.1 - 8.5e-07 29.6 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORX90938.1 - 1.1e-06 28.9 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ORX90938.1 - 0.00022 21.0 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 ORX90938.1 - 0.00054 19.9 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin2 PF13189.6 ORX90938.1 - 0.00092 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_22 PF13401.6 ORX90938.1 - 0.0076 16.5 0.1 0.013 15.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORX90938.1 - 0.009 16.4 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX90938.1 - 0.018 15.4 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 ORX90938.1 - 0.028 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PRK PF00485.18 ORX90938.1 - 0.037 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.11 ORX90938.1 - 0.042 13.9 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain dNK PF01712.19 ORX90938.1 - 0.051 13.4 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase RNA_helicase PF00910.22 ORX90938.1 - 0.053 13.9 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 ORX90938.1 - 0.069 13.4 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORX90938.1 - 0.089 13.3 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 ORX90938.1 - 0.096 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 ORX90938.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase RsgA_GTPase PF03193.16 ORX90938.1 - 0.16 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 ORX90938.1 - 0.18 11.0 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 ORX90938.1 - 0.22 11.6 0.0 0.45 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.27 ORX90939.1 - 6.3e-49 163.9 5.0 2.7e-17 62.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 ORX90940.1 - 2.2e-28 97.9 21.1 6e-06 26.9 0.1 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat HELP PF03451.14 ORX90940.1 - 8.5e-15 54.4 0.0 2.1e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 HELP motif C2 PF00168.30 ORX90940.1 - 4.6e-14 52.6 0.0 1.4e-13 51.0 0.0 1.9 1 0 0 1 1 1 1 C2 domain ANAPC4_WD40 PF12894.7 ORX90940.1 - 1.8e-07 31.4 1.8 1.2 9.4 0.1 6.7 3 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ORX90940.1 - 0.0029 16.7 0.1 1.9 7.4 0.0 3.1 2 1 1 3 3 3 2 Coatomer WD associated region Ge1_WD40 PF16529.5 ORX90940.1 - 0.019 14.0 0.1 28 3.5 0.0 3.9 3 2 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 ORX90940.1 - 0.048 14.2 0.0 6 7.5 0.0 3.2 2 0 0 2 2 2 0 PQQ-like domain 7tm_1 PF00001.21 ORX90941.1 - 0.00067 19.1 15.8 0.00096 18.6 15.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NICE-3 PF07406.11 ORX90941.1 - 0.0029 17.6 0.1 0.0029 17.6 0.1 2.4 3 0 0 3 3 3 1 NICE-3 protein DUF4834 PF16118.5 ORX90941.1 - 0.0056 17.6 3.4 0.036 15.0 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) DUF668 PF05003.12 ORX90941.1 - 0.048 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF4017 PF13209.6 ORX90941.1 - 0.076 13.0 6.6 0.12 12.3 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) GPR_Gpa2_C PF11970.8 ORX90941.1 - 0.097 12.8 0.5 0.097 12.8 0.5 2.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4131 PF13567.6 ORX90941.1 - 0.43 10.2 6.7 20 4.8 2.3 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) HemY_N PF07219.13 ORX90941.1 - 0.86 9.8 3.8 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF2975 PF11188.8 ORX90941.1 - 0.87 9.5 0.0 0.87 9.5 0.0 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF2975) LOR PF04525.12 ORX90942.1 - 6.2e-22 78.1 0.0 7.1e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related Glyco_hydro_16 PF00722.21 ORX90943.1 - 7.7e-35 119.9 4.6 7.7e-35 119.9 4.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Plasmodium_Vir PF05795.11 ORX90943.1 - 0.014 14.8 10.3 0.028 13.8 10.3 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sec3_C PF09763.9 ORX90943.1 - 0.037 12.4 1.8 0.042 12.2 1.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 SPX PF03105.19 ORX90943.1 - 2.1 8.2 19.2 2.9 7.7 19.2 1.1 1 0 0 1 1 1 0 SPX domain SpoIIIAH PF12685.7 ORX90943.1 - 5.7 6.7 15.0 8.7 6.1 15.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 ORX90943.1 - 7.3 5.2 12.0 11 4.6 12.0 1.2 1 0 0 1 1 1 0 Presenilin ABC2_membrane PF01061.24 ORX90944.1 - 2.1e-90 301.7 60.4 1.1e-48 165.4 23.3 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 ORX90944.1 - 5.3e-39 132.0 9.6 2.4e-35 120.3 0.1 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 ORX90944.1 - 6e-38 130.5 0.0 2.7e-17 63.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 ORX90944.1 - 7.2e-19 68.2 0.0 1.6e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ORX90944.1 - 6e-06 26.0 0.1 8e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORX90944.1 - 1.3e-05 25.1 0.4 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 ORX90944.1 - 1.8e-05 24.9 0.2 0.0041 17.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX90944.1 - 1.8e-05 25.2 0.2 0.0044 17.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORX90944.1 - 0.00085 19.0 1.6 0.028 14.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORX90944.1 - 0.0015 18.4 0.0 2.9 7.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 ORX90944.1 - 0.0039 17.7 0.1 0.058 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORX90944.1 - 0.0041 16.6 0.0 0.47 9.9 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 ORX90944.1 - 0.007 16.3 2.4 3.6 7.5 0.2 3.2 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 ORX90944.1 - 0.024 14.9 1.2 1.3 9.3 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORX90944.1 - 0.037 13.7 1.0 3.1 7.5 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 ORX90944.1 - 0.041 14.3 0.1 5.3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORX90944.1 - 0.045 13.5 0.1 4.5 7.0 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 ORX90944.1 - 0.077 12.6 0.9 0.34 10.5 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ORX90944.1 - 0.28 11.6 0.7 30 5.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 ORX90944.1 - 1.9 7.5 54.2 0.26 10.4 23.9 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein F420_oxidored PF03807.17 ORX90947.1 - 4.3e-13 49.7 0.0 7.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX90947.1 - 3.9e-07 29.6 0.0 8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORX90947.1 - 0.00068 19.2 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 ORX90947.1 - 0.00088 19.5 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ferric_reduct PF01794.19 ORX90947.1 - 0.0092 16.1 6.8 0.0092 16.1 6.8 2.1 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_Gly3P_dh_N PF01210.23 ORX90947.1 - 0.066 13.2 0.5 1.6 8.7 0.2 2.2 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mn_catalase PF05067.12 ORX90947.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Manganese containing catalase DUF3291 PF11695.8 ORX90950.1 - 2e-57 192.8 0.2 2.2e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) DUF3291 PF11695.8 ORX90951.1 - 2e-57 192.8 0.2 2.2e-57 192.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) 7tm_1 PF00001.21 ORX90952.1 - 0.02 14.3 11.5 0.084 12.2 11.0 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Anticodon_1 PF08264.13 ORX90952.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA PHO4 PF01384.20 ORX90952.1 - 1.2 8.1 8.9 0.054 12.5 0.7 2.2 1 1 1 2 2 2 0 Phosphate transporter family Myb_DNA-binding PF00249.31 ORX90953.1 - 1.8e-43 146.5 9.9 1.5e-14 53.9 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX90953.1 - 8e-31 106.1 0.1 2e-12 47.1 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORX90953.1 - 0.00027 21.3 9.4 0.44 11.0 0.1 4.8 5 1 0 5 5 5 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 ORX90953.1 - 0.00027 20.9 0.2 0.85 9.7 0.1 3.8 2 2 1 3 3 3 1 SLIDE Rap1_C PF11626.8 ORX90953.1 - 0.0018 18.3 0.1 8.6 6.5 0.0 3.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 ORX90953.1 - 0.016 15.1 0.5 8.5 6.4 0.0 3.4 4 0 0 4 4 4 0 Myb DNA-binding like DUF5591 PF17884.1 ORX90953.1 - 0.087 12.7 1.6 0.19 11.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5591) Rap1-DNA-bind PF09197.10 ORX90953.1 - 0.09 13.4 0.1 17 6.1 0.0 3.5 4 1 0 4 4 4 0 Rap1, DNA-binding TraI PF07057.11 ORX90953.1 - 0.25 11.5 1.3 0.82 9.8 1.1 1.9 1 1 1 2 2 2 0 DNA helicase TraI DUF1844 PF08899.11 ORX90953.1 - 0.27 11.6 2.5 20 5.5 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) DUF2937 PF11157.8 ORX90953.1 - 0.42 10.3 3.4 0.67 9.7 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) bZIP_1 PF00170.21 ORX90954.1 - 3.7e-14 52.6 12.0 3.7e-14 52.6 12.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORX90954.1 - 1.7e-12 47.2 16.2 1.7e-12 47.2 16.2 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX90954.1 - 1.8e-06 28.3 8.3 1.8e-06 28.3 8.3 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor HALZ PF02183.18 ORX90954.1 - 0.0026 17.9 3.0 0.0045 17.2 3.0 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Nnf1 PF03980.14 ORX90954.1 - 0.012 16.0 2.8 0.012 16.0 2.8 1.9 2 0 0 2 2 2 0 Nnf1 Fungal_TACC PF12709.7 ORX90954.1 - 0.013 15.9 4.4 0.031 14.7 4.4 1.6 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins SSXT PF05030.12 ORX90954.1 - 0.025 14.2 0.2 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) TMCO5 PF14992.6 ORX90954.1 - 0.028 14.0 6.5 0.039 13.5 6.5 1.2 1 0 0 1 1 1 0 TMCO5 family GIT_CC PF16559.5 ORX90954.1 - 0.03 14.2 1.1 0.058 13.3 1.1 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 ORX90954.1 - 0.037 14.1 1.1 0.07 13.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LCD1 PF09798.9 ORX90954.1 - 0.18 10.3 8.6 0.24 9.9 8.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DivIC PF04977.15 ORX90954.1 - 0.22 11.3 4.0 0.41 10.5 4.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Rhomboid PF01694.22 ORX90955.1 - 7.5e-30 103.9 12.3 7.6e-30 103.9 11.0 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 ORX90955.1 - 0.0014 19.2 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) CS PF04969.16 ORX90956.1 - 1e-09 39.3 0.0 1.6e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 CS domain STELLO PF03385.17 ORX90956.1 - 0.0083 15.0 0.0 0.0083 15.0 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases Form_Nir_trans PF01226.17 ORX90957.1 - 1.2e-68 231.0 24.9 1.3e-68 230.8 24.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter LPD15 PF18828.1 ORX90957.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 DBD_Tnp_Hermes PF10683.9 ORX90957.1 - 0.12 12.1 0.2 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain Form_Nir_trans PF01226.17 ORX90958.1 - 8.8e-69 231.4 25.1 9.9e-69 231.3 25.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DBD_Tnp_Hermes PF10683.9 ORX90958.1 - 0.095 12.4 0.2 0.6 9.8 0.1 2.2 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain LPD15 PF18828.1 ORX90958.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 Form_Nir_trans PF01226.17 ORX90959.1 - 1.1e-66 224.6 27.1 1.3e-66 224.3 27.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter UPF0052 PF01933.18 ORX90960.1 - 1.1e-48 165.9 0.0 1.4e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Peptidase_S66 PF02016.15 ORX90960.1 - 0.018 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain WD40 PF00400.32 ORX90961.1 - 2.3e-21 75.7 0.4 0.0012 19.7 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX90961.1 - 9.7e-08 32.2 0.0 0.92 9.8 0.0 4.4 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 ORX90961.1 - 0.0093 14.3 0.0 1.4 7.1 0.0 2.8 2 1 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz CNH PF00780.22 ORX90961.1 - 0.01 15.4 0.0 0.093 12.3 0.0 2.0 2 0 0 2 2 2 0 CNH domain Ge1_WD40 PF16529.5 ORX90961.1 - 0.021 13.8 0.3 5.9 5.7 0.0 2.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NUP214 PF16755.5 ORX90961.1 - 0.07 12.4 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 YCII PF03795.14 ORX90962.1 - 1.9e-12 47.4 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain ORC4_C PF14629.6 ORX90963.1 - 1.2e-47 162.1 0.1 2e-47 161.4 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 ORX90963.1 - 7.3e-18 65.5 0.5 1.7e-17 64.3 0.5 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX90963.1 - 2e-10 41.1 0.2 1e-09 38.8 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 ORX90963.1 - 1.4e-08 35.2 0.0 3.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX90963.1 - 3.1e-08 33.7 0.3 5.6e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 NACHT domain DUF815 PF05673.13 ORX90963.1 - 3.5e-08 32.9 0.1 5.8e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 ORX90963.1 - 3e-07 30.6 0.5 5.4e-07 29.8 0.5 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DAP3 PF10236.9 ORX90963.1 - 0.00089 18.5 0.8 0.083 12.0 0.1 2.2 1 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DUF2791 PF10923.8 ORX90963.1 - 0.00094 18.1 0.1 0.0052 15.7 0.0 1.9 2 0 0 2 2 2 1 P-loop Domain of unknown function (DUF2791) TniB PF05621.11 ORX90963.1 - 0.0014 18.1 0.1 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 ORX90963.1 - 0.0032 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 ORX90963.1 - 0.0083 16.1 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORX90963.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 ORX90963.1 - 0.011 15.9 0.0 0.042 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORX90963.1 - 0.012 14.9 0.0 0.15 11.3 0.0 2.4 2 1 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 ORX90963.1 - 0.013 14.8 0.0 0.058 12.6 0.0 2.3 1 1 0 1 1 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 ORX90963.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 ORX90963.1 - 0.02 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 ORX90963.1 - 0.023 14.7 2.3 0.086 12.9 0.7 2.7 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORX90963.1 - 0.033 13.3 3.6 1.4 8.0 3.6 2.4 1 1 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 ORX90963.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 ORX90963.1 - 0.071 12.2 0.1 0.17 10.9 0.1 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 ORX90963.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 ORX90963.1 - 0.15 12.6 0.3 0.32 11.5 0.2 1.8 1 1 0 1 1 1 0 ABC transporter LRR_8 PF13855.6 ORX90964.1 - 4.7e-15 55.1 12.7 4.9e-06 26.2 1.6 3.8 2 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORX90964.1 - 2.2e-14 53.3 11.8 5.7e-05 23.4 1.0 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX90964.1 - 6.6e-06 26.0 16.8 0.75 10.6 0.7 6.3 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 ORX90964.1 - 8.7e-05 22.3 14.3 1 9.6 0.1 5.0 5 0 0 5 5 5 3 Leucine Rich repeat CSTF_C PF14304.6 ORX90964.1 - 0.019 14.6 0.8 8.9 6.0 0.4 2.7 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal LRR_9 PF14580.6 ORX90964.1 - 0.13 11.8 3.1 0.57 9.7 0.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Acyltransferase PF01553.21 ORX90965.1 - 2.9e-33 114.3 0.0 4.6e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Lactamase_B PF00753.27 ORX90966.1 - 1e-16 61.5 0.0 1.4e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX90966.1 - 9.5e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Homeodomain PF00046.29 ORX90967.1 - 6.1e-18 64.4 4.0 1.4e-17 63.3 4.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX90967.1 - 0.03 14.2 3.9 0.06 13.3 0.3 2.5 2 0 0 2 2 2 0 Homeobox KN domain Uds1 PF15456.6 ORX90968.1 - 6.1e-23 81.4 8.1 6.1e-23 81.4 8.1 3.5 2 1 1 3 3 3 1 Up-regulated During Septation Arfaptin PF06456.13 ORX90968.1 - 0.0054 16.3 0.2 0.0054 16.3 0.2 2.4 2 1 0 2 2 2 1 Arfaptin-like domain DUF3747 PF12565.8 ORX90968.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) HNH_2 PF13391.6 ORX90968.1 - 0.15 12.2 0.3 0.53 10.5 0.3 1.9 1 0 0 1 1 1 0 HNH endonuclease DUF3675 PF12428.8 ORX90968.1 - 0.16 12.5 0.5 6.6 7.3 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3675) T4SS PF07996.11 ORX90968.1 - 1.7 9.0 12.0 1.2 9.5 5.0 3.0 3 0 0 3 3 3 0 Type IV secretion system proteins RPW8 PF05659.11 ORX90968.1 - 4.2 7.1 9.1 0.66 9.7 0.9 3.0 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 HR1 PF02185.16 ORX90968.1 - 5.5 7.2 13.1 7.9 6.7 0.8 3.7 3 1 0 3 3 3 0 Hr1 repeat Cep57_MT_bd PF06657.13 ORX90968.1 - 7.3 7.1 11.3 7.4 7.1 2.2 3.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.16 ORX90969.1 - 1.4e-26 93.2 46.7 1.4e-26 93.2 46.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX90969.1 - 5.8e-06 25.4 39.1 0.00027 19.9 21.5 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Ebp2 PF05890.12 ORX90970.1 - 3.3e-96 321.9 17.6 3.8e-96 321.7 17.6 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Cdh1_DBD_1 PF18196.1 ORX90970.1 - 1.5 9.1 11.6 1.8 8.9 9.9 2.0 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 EMC3_TMCO1 PF01956.16 ORX90970.1 - 1.6 8.4 5.1 2.3 7.9 5.1 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ribosomal_L37e PF01907.19 ORX90971.1 - 9.6e-28 96.1 13.0 1.7e-27 95.3 13.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX90971.1 - 0.0059 16.6 1.6 0.0093 16.0 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORX90971.1 - 0.033 14.2 0.9 0.047 13.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORX90971.1 - 0.22 11.0 3.6 2.3 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORX90971.1 - 0.65 9.9 5.4 1.1 9.2 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CK_II_beta PF01214.18 ORX90972.1 - 1.6e-66 223.6 0.0 2e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PPR_2 PF13041.6 ORX90977.1 - 4.8e-48 161.1 3.5 2.1e-11 43.8 0.2 9.6 5 1 5 10 10 10 7 PPR repeat family PPR PF01535.20 ORX90977.1 - 4.1e-34 114.4 2.2 8.3e-05 22.6 0.0 11.1 11 0 0 11 11 11 8 PPR repeat PPR_3 PF13812.6 ORX90977.1 - 4.1e-32 110.0 1.0 1.6e-05 24.9 0.0 8.5 6 3 4 10 10 10 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX90977.1 - 1.8e-19 70.0 0.0 0.00014 21.3 0.0 5.3 1 1 3 5 5 5 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORX90977.1 - 1.3e-12 47.2 3.6 1.4 8.7 0.0 8.6 10 0 0 10 10 10 4 PPR repeat TPR_14 PF13428.6 ORX90977.1 - 0.00022 21.8 0.3 55 5.0 0.0 5.9 6 3 2 8 8 8 0 Tetratricopeptide repeat DUF3067 PF11267.8 ORX90977.1 - 0.0081 16.7 0.0 0.028 15.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) Pyr_excise PF03013.14 ORX90977.1 - 0.14 12.2 0.1 20 5.1 0.0 2.6 2 1 0 2 2 2 0 Pyrimidine dimer DNA glycosylase PAS_3 PF08447.12 ORX90978.1 - 6.6e-16 58.4 0.0 1.5e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORX90978.1 - 1.3e-11 44.5 0.0 4.6e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORX90978.1 - 1.3e-06 28.6 0.0 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 ORX90978.1 - 0.00016 21.8 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX90978.1 - 0.00017 21.8 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold TCO89 PF10452.9 ORX90979.1 - 1.6e-06 27.4 0.3 2.7e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 TORC1 subunit TCO89 FYVE PF01363.21 ORX90980.1 - 6.7e-13 48.6 4.6 6.7e-13 48.6 4.6 3.0 2 1 0 3 3 3 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 ORX90980.1 - 1.7e-12 47.0 14.5 1.7e-12 47.0 14.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX90980.1 - 0.0045 17.3 14.9 0.0045 17.3 14.9 2.7 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 ORX90980.1 - 0.0064 16.3 13.5 0.0064 16.3 13.5 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 HeH PF12949.7 ORX90980.1 - 0.0071 16.0 0.0 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 HeH/LEM domain zf-RING_5 PF14634.6 ORX90980.1 - 0.25 11.4 33.4 0.19 11.7 15.3 2.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORX90980.1 - 0.25 11.2 31.4 0.076 12.9 16.3 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RGS PF00615.19 ORX90981.1 - 4.9e-18 65.5 2.4 4.9e-18 65.5 2.4 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORX90981.1 - 0.0068 16.1 1.7 0.064 13.0 0.1 2.7 1 1 1 2 2 2 1 Regulator of G protein signalling-like domain RGI1 PF10843.8 ORX90981.1 - 0.057 13.1 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Respiratory growth induced protein 1 Troponin-I_N PF11636.8 ORX90981.1 - 0.58 10.2 4.2 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 Troponin I residues 1-32 Cation_efflux PF01545.21 ORX90982.1 - 1.7e-54 184.6 8.9 2.2e-54 184.2 8.9 1.1 1 0 0 1 1 1 1 Cation efflux family PsbJ PF01788.17 ORX90982.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.3 2 0 0 2 2 2 0 PsbJ Ras PF00071.22 ORX90983.1 - 2.5e-56 189.8 0.1 3.1e-56 189.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90983.1 - 6.7e-36 123.1 0.0 1.1e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90983.1 - 1.7e-18 66.7 0.1 1.9e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX90983.1 - 3.9e-07 29.7 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX90983.1 - 5.2e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX90983.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX90983.1 - 0.00019 21.4 0.1 0.29 11.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORX90983.1 - 0.0054 17.1 0.0 0.0075 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain REGB_T4 PF10715.9 ORX90983.1 - 0.11 12.8 0.0 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 T4-page Endoribonuclease RegB AAA_22 PF13401.6 ORX90983.1 - 0.14 12.4 0.0 0.67 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 ORX90984.1 - 1e-54 184.5 0.0 1.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX90984.1 - 5.9e-23 81.4 0.0 8.9e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX90984.1 - 1.5e-10 40.8 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX90984.1 - 2e-06 27.3 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORX90984.1 - 0.00039 19.9 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORX90984.1 - 0.0012 18.5 0.0 0.0031 17.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX90984.1 - 0.003 17.6 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORX90984.1 - 0.0035 16.5 0.0 0.0071 15.5 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 ORX90984.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 ORX90984.1 - 0.074 13.4 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 ORX90984.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 ORX90984.1 - 0.16 11.9 0.2 12 5.8 0.0 2.2 1 1 0 2 2 2 0 RsgA GTPase CRAL_TRIO PF00650.20 ORX90985.1 - 1.2e-17 64.1 0.1 2.3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORX90985.1 - 2.2e-07 31.1 0.0 3.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DDHD PF02862.17 ORX90986.1 - 3.6e-31 109.1 1.5 6.8e-31 108.2 0.9 1.7 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.14 ORX90986.1 - 0.0023 17.5 0.0 0.008 15.7 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Rxt3 PF08642.10 ORX90987.1 - 2.7e-07 31.4 0.1 2.7e-07 31.4 0.1 4.9 4 1 0 4 4 4 1 Histone deacetylation protein Rxt3 zf-C2H2_jaz PF12171.8 ORX90988.1 - 2.7e-05 24.3 1.5 2.7e-05 24.3 1.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORX90988.1 - 5e-05 23.5 2.9 5e-05 23.5 2.9 2.5 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX90988.1 - 0.0003 21.4 2.1 0.0003 21.4 2.1 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX90988.1 - 0.00039 20.7 3.0 0.00039 20.7 3.0 2.7 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORX90988.1 - 0.0041 17.1 1.9 0.0041 17.1 1.9 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-TRAF PF02176.18 ORX90988.1 - 0.014 16.1 5.0 0.016 15.9 4.5 1.5 1 1 0 1 1 1 0 TRAF-type zinc finger zf-LYAR PF08790.11 ORX90988.1 - 0.1 12.6 0.6 0.1 12.6 0.6 2.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORX90988.1 - 0.14 12.5 6.8 0.24 11.7 1.6 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) HNH PF01844.23 ORX90988.1 - 0.49 10.6 8.5 2.5 8.4 0.6 2.8 2 1 1 3 3 3 0 HNH endonuclease zf-C2HE PF16278.5 ORX90988.1 - 3.8 8.0 8.3 5.3 7.6 1.3 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger HNH_5 PF14279.6 ORX90988.1 - 4.2 7.3 9.0 8.2 6.4 0.6 3.0 2 1 1 3 3 3 0 HNH endonuclease F-box-like PF12937.7 ORX90989.1 - 2.1e-05 24.3 3.8 5.2e-05 23.1 3.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX90989.1 - 2.7e-05 23.9 2.9 6.9e-05 22.6 2.9 1.7 1 0 0 1 1 1 1 F-box domain SMI1_KNR4 PF09346.10 ORX90989.1 - 0.001 19.5 0.5 0.0022 18.4 0.5 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORX90989.1 - 0.017 15.5 0.1 0.48 10.9 0.0 3.1 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall His_Phos_2 PF00328.22 ORX90990.1 - 7.2e-22 78.3 0.0 1e-18 67.9 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) KH_1 PF00013.29 ORX90991.1 - 7e-32 109.1 17.5 1.3e-11 44.2 3.9 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX90991.1 - 8.9e-12 44.7 1.7 0.0049 16.7 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX90991.1 - 1.3e-07 31.4 11.1 0.042 13.7 0.5 3.8 3 1 1 4 4 4 3 KH domain MOEP19 PF16005.5 ORX90991.1 - 0.00019 21.3 0.1 0.023 14.7 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_5 PF13184.6 ORX90991.1 - 0.0016 18.5 6.3 1.7 8.8 0.3 3.8 3 1 0 3 3 3 2 NusA-like KH domain ADK PF00406.22 ORX90992.1 - 9e-51 171.9 0.0 1.1e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORX90992.1 - 4.1e-20 72.6 0.0 8.6e-20 71.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORX90992.1 - 3.1e-12 46.3 0.0 4.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORX90992.1 - 1.4e-06 28.9 0.0 2.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORX90992.1 - 0.0025 18.0 0.0 0.0079 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORX90992.1 - 0.02 14.2 0.0 0.053 12.8 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.29 ORX90992.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SVIP PF15811.5 ORX90993.1 - 0.0022 18.4 6.0 0.0056 17.1 1.3 2.2 2 0 0 2 2 2 2 Small VCP/p97-interacting protein Pkinase PF00069.25 ORX90994.1 - 3.7e-76 256.0 0.0 9e-76 254.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX90994.1 - 4.3e-32 111.4 0.0 2e-21 76.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORX90994.1 - 1.1e-08 34.7 0.8 0.013 14.8 0.0 3.1 2 1 0 3 3 3 3 Kinase-like Haspin_kinase PF12330.8 ORX90994.1 - 0.019 14.0 0.5 0.59 9.0 0.0 2.4 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 ORX90994.1 - 0.035 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX90994.1 - 0.15 10.8 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Inhibitor_Mig-6 PF11555.8 ORX90994.1 - 0.17 12.0 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 DUF3959 PF13105.6 ORX90995.1 - 0.11 12.0 0.6 0.15 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Gpr1_Fun34_YaaH PF01184.19 ORX90996.1 - 4.8e-73 245.2 25.5 5.3e-73 245.0 25.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Defb50 PF17546.2 ORX90997.1 - 1.4 8.9 7.8 0.11 12.4 1.8 2.3 3 0 0 3 3 3 0 Beta defensin 50 Ank_4 PF13637.6 ORX90998.1 - 0.0053 17.3 0.1 0.083 13.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) GTPase_binding PF09027.10 ORX90998.1 - 0.058 13.4 0.4 1.5 8.9 0.2 2.3 2 0 0 2 2 2 0 GTPase binding Ank_2 PF12796.7 ORX90998.1 - 0.14 12.7 0.1 1.6 9.3 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) zf-Nse PF11789.8 ORX90999.1 - 3.6e-18 65.1 1.5 5.6e-18 64.5 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 ORX90999.1 - 2.2e-05 24.5 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 ORX90999.1 - 0.0003 20.7 0.3 0.00055 19.9 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX90999.1 - 0.00037 20.3 0.2 0.00069 19.4 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 ORX90999.1 - 0.00044 19.9 0.5 0.00087 19.0 0.5 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 ORX90999.1 - 0.00085 19.4 0.1 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORX90999.1 - 0.007 16.2 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX90999.1 - 0.04 14.3 0.6 0.07 13.5 0.6 1.4 1 0 0 1 1 1 0 Ring finger domain DUF2573 PF10835.8 ORX90999.1 - 0.045 14.1 0.1 0.21 12.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) Alba PF01918.21 ORX90999.1 - 0.13 12.1 0.2 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Alba zf-RING_6 PF14835.6 ORX90999.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Dor1 PF04124.12 ORX91000.1 - 2.8e-78 263.0 5.5 3.8e-78 262.5 5.5 1.2 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 ORX91000.1 - 0.0011 18.4 1.2 0.0023 17.2 1.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 ORX91000.1 - 0.0018 17.0 1.9 0.0027 16.4 1.9 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps51 PF08700.11 ORX91000.1 - 0.015 15.3 6.0 0.045 13.8 0.3 3.2 2 1 0 3 3 3 0 Vps51/Vps67 COG2 PF06148.11 ORX91000.1 - 0.038 14.1 1.3 0.15 12.2 1.3 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 ORX91000.1 - 1.6 8.9 10.0 0.25 11.5 1.4 3.3 3 1 0 4 4 4 0 Golgi transport complex subunit 5 Arrestin_C PF02752.22 ORX91001.1 - 1.5e-16 61.1 0.1 1e-12 48.7 0.1 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX91001.1 - 6e-09 36.1 0.0 3.3e-08 33.7 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Thioredoxin PF00085.20 ORX91002.1 - 1.9e-30 104.9 0.0 2.3e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORX91002.1 - 6.1e-06 26.7 0.2 8.4e-05 23.0 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORX91002.1 - 7.5e-06 25.9 0.0 8.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 ORX91002.1 - 0.00019 20.9 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORX91002.1 - 0.00067 19.9 0.0 0.00099 19.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ORX91002.1 - 0.0029 17.7 0.0 0.0036 17.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 ORX91002.1 - 0.01 15.5 0.2 0.08 12.7 0.1 1.9 1 1 1 2 2 2 0 Redoxin Thioredoxin_9 PF14595.6 ORX91002.1 - 0.021 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Nucleocap_ssRNA PF11128.8 ORX91002.1 - 0.082 12.6 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Plant viral coat protein nucleocapsid FMO-like PF00743.19 ORX91003.1 - 1.3e-50 172.3 0.0 3.4e-30 105.0 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORX91003.1 - 5e-17 62.1 0.1 2.8e-13 49.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX91003.1 - 1.9e-09 37.2 0.0 5.9e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX91003.1 - 1.1e-07 32.0 0.5 1.8e-05 24.8 0.0 2.9 2 1 2 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORX91003.1 - 1.4e-07 31.6 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORX91003.1 - 7e-07 28.7 0.0 0.00092 18.4 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORX91003.1 - 2.7e-05 23.9 0.2 0.0014 18.3 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORX91003.1 - 0.0041 16.4 0.1 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORX91003.1 - 0.0054 15.5 0.1 0.0083 14.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 ORX91003.1 - 0.028 14.5 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ORX91003.1 - 0.084 13.4 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX91003.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein LRR_6 PF13516.6 ORX91004.1 - 0.085 13.0 20.1 1.1 9.5 1.5 6.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 ORX91004.1 - 5.2 8.0 18.4 14 6.7 0.0 7.3 8 0 0 8 8 8 0 Leucine Rich Repeat MoCF_biosynth PF00994.24 ORX91005.1 - 9.4e-36 122.6 0.0 1.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Flt3_lig PF02947.14 ORX91005.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 flt3 ligand Prok-RING_4 PF14447.6 ORX91006.1 - 6.7e-06 25.9 12.0 1.2e-05 25.1 12.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORX91006.1 - 1.1e-05 25.2 13.9 1.8e-05 24.5 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX91006.1 - 1.5e-05 24.8 14.5 2.5e-05 24.1 14.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORX91006.1 - 0.00074 19.8 13.3 0.0013 19.0 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX91006.1 - 0.0012 18.7 14.4 0.0022 17.8 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX91006.1 - 0.0039 17.0 13.7 0.0073 16.2 13.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX91006.1 - 0.0046 16.9 7.9 0.012 15.7 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORX91006.1 - 0.11 12.9 9.1 0.24 11.7 9.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORX91006.1 - 0.12 12.3 4.2 0.23 11.4 4.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORX91006.1 - 0.65 9.8 10.5 1.1 9.2 10.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 ORX91006.1 - 0.93 9.7 9.5 1.6 8.9 9.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ORX91006.1 - 1.2 9.4 11.6 4 7.7 11.8 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 ORX91006.1 - 1.6 8.8 11.4 2.8 8.0 11.4 1.4 1 0 0 1 1 1 0 zinc-ribbons p450 PF00067.22 ORX91007.1 - 2.2e-96 323.4 0.0 3.1e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORX91007.1 - 1.9e-32 112.6 0.0 2.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX91007.1 - 9.4e-23 81.0 0.0 2.5e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORX91007.1 - 2.1e-12 47.6 0.1 1.8e-11 44.6 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Alkyl_sulf_dimr PF14863.6 ORX91008.1 - 1.1e-54 184.6 2.7 2.1e-54 183.7 2.7 1.5 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.6 ORX91008.1 - 1.4e-29 102.9 0.0 2.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.27 ORX91008.1 - 1.2e-24 87.4 0.0 6.4e-24 85.1 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX91008.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 ORX91008.1 - 0.12 11.4 0.6 0.2 10.7 0.1 1.5 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II CBAH PF02275.18 ORX91009.1 - 0.014 15.1 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family COG5 PF10392.9 ORX91010.1 - 0.045 13.9 0.3 0.14 12.3 0.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V-ATPase_G PF03179.15 ORX91010.1 - 0.52 10.9 2.9 0.43 11.1 0.5 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit adh_short PF00106.25 ORX91013.1 - 4.8e-46 156.7 0.0 5.7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX91013.1 - 1.2e-34 119.9 0.0 1.4e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX91013.1 - 5.3e-09 36.2 0.0 7.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX91013.1 - 0.0011 19.0 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX91013.1 - 0.038 13.4 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GPI-anchored PF10342.9 ORX91014.1 - 3.5e-10 40.5 1.2 4.5e-10 40.1 0.0 1.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_S28 PF05577.12 ORX91015.1 - 8.3e-77 258.8 0.0 1.1e-76 258.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 ORX91015.1 - 0.0025 17.5 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX91015.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1397 PF07165.11 ORX91015.1 - 0.16 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) E1-E2_ATPase PF00122.20 ORX91016.1 - 2.3e-49 167.4 0.5 9.1e-49 165.4 0.5 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORX91016.1 - 7.7e-40 137.4 0.0 1.5e-39 136.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORX91016.1 - 9.2e-11 42.0 0.0 1.9e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORX91016.1 - 4.1e-07 30.0 0.1 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX91016.1 - 0.00021 21.7 0.0 0.00073 20.0 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORX91016.1 - 0.015 15.4 0.3 5.3 7.2 0.0 3.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Spc7 PF08317.11 ORX91017.1 - 0.00012 21.1 39.4 0.00027 19.9 18.1 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein fn3 PF00041.21 ORX91017.1 - 0.0092 16.3 0.2 0.046 14.1 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Prominin PF05478.11 ORX91017.1 - 0.033 12.2 14.7 0.063 11.2 14.7 1.4 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 ORX91017.1 - 0.033 14.2 12.0 0.022 14.8 4.8 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZnuA PF01297.17 ORX91017.1 - 0.08 12.3 5.2 0.073 12.5 3.4 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1664 PF07889.12 ORX91017.1 - 0.12 12.5 21.2 0.69 10.0 7.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 ORX91017.1 - 0.13 12.1 20.8 2.1 8.1 9.7 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Dna2 PF08696.11 ORX91017.1 - 0.42 10.4 7.8 0.94 9.2 7.8 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF3584 PF12128.8 ORX91017.1 - 1.3 6.4 32.7 1.7 6.1 32.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myb_DNA-bind_4 PF13837.6 ORX91017.1 - 1.4 9.3 8.6 4.6 7.7 0.8 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Golgin_A5 PF09787.9 ORX91017.1 - 6 6.2 36.4 15 4.9 10.7 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 IFT57 PF10498.9 ORX91017.1 - 6.2 5.7 25.7 8.7 5.2 24.2 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF725 PF05267.12 ORX91017.1 - 6.4 6.8 7.6 0.89 9.6 3.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF725) E2F_CC-MB PF16421.5 ORX91017.1 - 7.6 7.0 12.3 5.6 7.4 3.9 2.7 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain COG2 PF06148.11 ORX91017.1 - 8.4 6.5 23.3 0.42 10.7 3.8 3.9 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.12 ORX91017.1 - 9.4 6.5 10.0 11 6.3 0.6 3.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Ribonuc_P_40 PF08584.11 ORX91018.1 - 1.5e-50 172.1 0.0 1.5e-50 172.1 0.0 3.8 4 1 1 5 5 5 1 Ribonuclease P 40kDa (Rpp40) subunit Cytokin_check_N PF10407.9 ORX91018.1 - 1.9e-17 63.0 0.0 4e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Mif2_N PF15624.6 ORX91019.1 - 0.042 14.6 0.1 0.11 13.2 0.1 1.8 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Peptidase_S8 PF00082.22 ORX91020.1 - 9.6e-40 136.7 0.3 1.5e-39 136.1 0.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORX91020.1 - 3.2e-26 91.2 0.1 6.5e-26 90.2 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORX91020.1 - 0.00031 21.5 0.5 0.00072 20.3 0.5 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORX91020.1 - 0.17 12.4 0.0 0.56 10.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal of Subtilase family Exo_endo_phos PF03372.23 ORX91022.1 - 4.6e-07 29.6 0.0 6.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4778 PF16008.5 ORX91022.1 - 0.039 14.0 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Scs3p PF10261.9 ORX91023.1 - 1.8e-20 73.5 11.5 7.7e-12 45.2 2.9 2.1 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM T-box PF00907.22 ORX91024.1 - 2.3e-49 168.2 0.3 3.9e-49 167.4 0.3 1.4 1 0 0 1 1 1 1 T-box ACOX PF01756.19 ORX91027.1 - 8.5e-54 181.8 0.0 1.7e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORX91027.1 - 9.1e-21 73.9 0.4 1.6e-20 73.1 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORX91027.1 - 1.1e-11 45.3 0.0 2.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORX91027.1 - 3.8e-07 30.4 0.2 1.8e-06 28.2 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4272 PF14094.6 ORX91028.1 - 2.7e-07 30.0 0.0 8.4e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4272) GPI-anchored PF10342.9 ORX91030.1 - 7.7e-15 55.4 0.4 7.7e-15 55.4 0.4 3.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORX91031.1 - 3.8e-10 40.4 0.1 3.8e-10 40.4 0.1 2.7 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Spore_coat_CotO PF14153.6 ORX91031.1 - 0.0095 15.9 1.4 0.011 15.7 1.4 1.2 1 0 0 1 1 1 1 Spore coat protein CotO DUF572 PF04502.13 ORX91031.1 - 0.041 13.5 11.4 0.049 13.3 11.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Smg8_Smg9 PF10220.9 ORX91031.1 - 0.089 11.1 7.1 0.095 11.0 7.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 GREB1 PF15782.5 ORX91031.1 - 0.11 9.7 11.6 0.11 9.6 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 ORX91031.1 - 0.16 11.8 7.7 0.21 11.4 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 ORX91031.1 - 0.29 9.9 16.3 0.38 9.5 16.3 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 ORX91031.1 - 0.29 9.9 6.4 0.33 9.7 6.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 ORX91031.1 - 1 8.5 8.3 1.4 8.0 8.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.13 ORX91031.1 - 1.4 7.2 9.0 2.1 6.6 9.0 1.3 1 0 0 1 1 1 0 Menin Tim54 PF11711.8 ORX91031.1 - 1.7 7.4 8.2 2.8 6.6 8.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Raftlin PF15250.6 ORX91031.1 - 2 7.1 12.4 2.6 6.7 12.4 1.1 1 0 0 1 1 1 0 Raftlin Dsh_C PF12316.8 ORX91031.1 - 2.9 8.2 24.7 4.2 7.7 24.7 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4769 PF15992.5 ORX91031.1 - 3.7 7.3 5.8 4.8 6.9 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Lin-8 PF03353.15 ORX91031.1 - 5 6.6 11.5 6.8 6.2 11.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 ORX91031.1 - 5.4 5.5 22.5 7 5.1 22.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF5383 PF17355.2 ORX91031.1 - 5.8 7.3 11.4 24 5.3 11.4 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Membralin PF09746.9 ORX91031.1 - 6.9 5.6 7.4 9.4 5.2 7.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF1180 PF06679.12 ORX91031.1 - 8.7 6.7 10.1 16 5.9 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Tmemb_cc2 PF10267.9 ORX91031.1 - 9 5.3 13.0 12 5.0 13.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Myb_DNA-bind_4 PF13837.6 ORX91032.1 - 3.8e-13 49.6 1.5 2.8e-05 24.4 0.2 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX91032.1 - 0.00082 19.5 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX91032.1 - 0.0029 17.9 1.9 0.3 11.4 0.2 2.6 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORX91032.1 - 0.4 11.7 3.5 24 6.0 0.4 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain ABC1 PF03109.16 ORX91033.1 - 6.1e-33 113.5 0.1 1.2e-32 112.6 0.1 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORX91033.1 - 2.4e-05 24.0 0.1 8.7e-05 22.2 0.0 2.0 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.25 ORX91033.1 - 0.0014 18.0 0.0 0.052 12.9 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain REV1_C PF16727.5 ORX91034.1 - 0.1 13.0 0.3 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain EamA PF00892.20 ORX91035.1 - 3.4e-25 88.8 37.4 6.3e-15 55.6 15.9 2.0 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 ORX91035.1 - 0.00037 19.5 3.5 0.00068 18.7 3.5 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like RRM_1 PF00076.22 ORX91036.1 - 3.7e-23 81.1 1.3 5.6e-13 48.5 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX91036.1 - 0.16 12.1 0.1 0.86 9.8 0.1 2.2 1 1 0 1 1 1 0 RNA recognition motif GCN5L1 PF06320.13 ORX91037.1 - 6.9e-38 129.3 10.9 6.9e-38 129.3 10.9 2.1 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) bZIP_1 PF00170.21 ORX91037.1 - 4e-12 46.1 7.0 4e-12 46.1 7.0 3.4 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORX91037.1 - 6.7e-07 29.3 6.1 6.7e-07 29.3 6.1 2.7 3 0 0 3 3 3 1 Basic region leucine zipper HALZ PF02183.18 ORX91037.1 - 0.00031 20.9 5.4 0.0056 16.9 0.3 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_Maf PF03131.17 ORX91037.1 - 0.00054 20.4 6.0 0.00054 20.4 6.0 2.7 2 1 1 3 3 3 1 bZIP Maf transcription factor DUF4618 PF15397.6 ORX91037.1 - 0.17 11.3 13.4 0.081 12.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Prominin PF05478.11 ORX91037.1 - 0.48 8.3 9.9 1.2 7.0 0.7 2.0 2 0 0 2 2 2 0 Prominin AAA_13 PF13166.6 ORX91037.1 - 0.73 8.4 14.2 1 7.9 5.5 2.1 2 0 0 2 2 2 0 AAA domain PspA_IM30 PF04012.12 ORX91037.1 - 0.88 9.1 22.5 0.091 12.3 5.3 3.5 2 1 1 3 3 3 0 PspA/IM30 family Prefoldin_2 PF01920.20 ORX91037.1 - 1.1 9.3 15.3 0.23 11.4 1.3 3.5 2 1 1 3 3 3 0 Prefoldin subunit Synaptobrevin PF00957.21 ORX91037.1 - 1.4 8.7 7.7 6 6.7 1.1 2.4 2 0 0 2 2 2 0 Synaptobrevin GrpE PF01025.19 ORX91037.1 - 2.3 7.8 17.2 1.9 8.2 9.0 2.3 2 0 0 2 2 2 0 GrpE Exonuc_VII_L PF02601.15 ORX91037.1 - 4.8 6.7 9.9 6.6 6.2 3.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF745 PF05335.13 ORX91037.1 - 5.2 6.8 16.4 7.5 6.2 6.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) XhlA PF10779.9 ORX91037.1 - 7.4 6.9 12.5 7.3 6.9 2.2 3.3 2 1 1 3 3 3 0 Haemolysin XhlA DUF4407 PF14362.6 ORX91037.1 - 7.5 5.8 11.3 3.6 6.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WD40 PF00400.32 ORX91038.1 - 7e-54 178.6 24.4 2.2e-08 34.6 0.7 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91038.1 - 1.4e-17 63.7 8.5 0.015 15.6 0.0 6.8 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91038.1 - 7.6e-11 42.2 1.9 4.2e-05 23.5 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORX91038.1 - 0.00015 19.9 2.5 0.00029 19.0 1.3 2.0 1 1 1 2 2 2 1 IKI3 family Coatomer_WDAD PF04053.14 ORX91038.1 - 0.016 14.3 1.5 0.2 10.7 0.3 2.9 3 1 0 3 3 3 0 Coatomer WD associated region Carn_acyltransf PF00755.20 ORX91039.1 - 1.3e-193 644.8 0.0 1.5e-193 644.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YhdX PF17444.2 ORX91039.1 - 0.12 12.3 0.2 1 9.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized YhdX-like MTS PF05175.14 ORX91040.1 - 3.6e-09 36.4 0.0 6.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORX91040.1 - 1.1e-07 31.7 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 ORX91040.1 - 2e-06 28.3 0.2 3.9e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 ORX91040.1 - 9.2e-06 26.3 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 ORX91040.1 - 0.00027 20.8 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) N6_Mtase PF02384.16 ORX91040.1 - 0.00077 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 ORX91040.1 - 0.00078 19.2 0.0 0.0044 16.7 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 ORX91040.1 - 0.00093 18.9 0.0 0.0022 17.7 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 ORX91040.1 - 0.0026 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 ORX91040.1 - 0.0072 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa PCMT PF01135.19 ORX91040.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDP_Man_Dehyd PF16363.5 ORX91040.1 - 0.031 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_32 PF13679.6 ORX91040.1 - 0.044 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORX91040.1 - 0.055 14.2 0.0 0.14 12.9 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORX91040.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 ORX91040.1 - 0.059 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_15 PF09445.10 ORX91040.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ORX91040.1 - 0.074 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORX91040.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 ORX91040.1 - 0.09 12.1 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Rif1_N PF12231.8 ORX91041.1 - 9.8e-09 34.7 0.6 0.0027 16.8 0.1 2.1 2 0 0 2 2 2 2 Rap1-interacting factor 1 N terminal Ipi1_N PF12333.8 ORX91041.1 - 0.12 12.9 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation C2 PF00168.30 ORX91043.1 - 7.4e-14 51.9 0.0 8.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.16 ORX91044.1 - 2.5e-45 154.9 28.4 3.5e-42 144.6 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX91044.1 - 3.5e-08 32.7 1.3 3.5e-08 32.7 1.3 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 ORX91044.1 - 1.3e-05 24.0 12.8 1.3e-05 24.0 12.8 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_5 PF05631.14 ORX91044.1 - 0.00064 18.7 1.7 0.00064 18.7 1.7 2.4 1 1 1 2 2 2 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 ORX91044.1 - 0.00071 18.1 0.9 0.0014 17.2 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Frizzled PF01534.17 ORX91045.1 - 0.00021 20.4 10.8 0.00021 20.4 10.8 1.5 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region GPR_Gpa2_C PF11970.8 ORX91045.1 - 0.01 15.9 0.9 0.054 13.6 0.9 2.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term PgaD PF13994.6 ORX91045.1 - 0.035 14.2 1.5 0.035 14.2 1.5 1.9 2 0 0 2 2 2 0 PgaD-like protein MRAP PF15183.6 ORX91045.1 - 0.063 13.2 0.4 0.2 11.6 0.4 1.8 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family ANTH PF07651.16 ORX91046.1 - 3.6e-69 232.8 0.0 3.6e-69 232.8 0.0 3.6 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 ORX91046.1 - 3e-49 167.2 12.7 3e-49 167.2 12.7 6.9 3 2 1 5 5 5 2 I/LWEQ domain Gtr1_RagA PF04670.12 ORX91047.1 - 4.4e-104 346.9 1.8 5.4e-104 346.6 1.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX91047.1 - 7.8e-08 32.6 0.0 2.1e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX91047.1 - 9.3e-08 31.8 0.1 1.8e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 ORX91047.1 - 4.1e-07 29.6 0.0 6.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX91047.1 - 9.7e-06 25.3 0.1 1.2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX91047.1 - 9.9e-06 25.6 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX91047.1 - 0.019 14.9 0.3 0.66 9.9 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase ABC_sub_bind PF04392.12 ORX91047.1 - 0.17 11.1 0.2 1 8.6 0.1 1.9 2 0 0 2 2 2 0 ABC transporter substrate binding protein Occludin_ELL PF07303.13 ORX91048.1 - 3.3e-08 34.2 2.6 8.2e-08 32.9 2.6 1.6 1 0 0 1 1 1 1 Occludin homology domain ELL PF10390.9 ORX91048.1 - 3.6e-07 30.0 0.1 3.6e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL CLP1_N PF16573.5 ORX91048.1 - 0.06 13.6 0.4 0.17 12.1 0.3 1.9 1 1 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor DUF2028 PF09667.10 ORX91048.1 - 0.065 13.2 0.2 4.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2028) UPF0449 PF15136.6 ORX91048.1 - 0.22 12.0 5.0 3.4 8.2 0.5 2.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Nup35_RRM PF05172.13 ORX91049.1 - 1.9e-20 72.7 0.0 4.1e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORX91049.1 - 2.8e-06 27.2 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_M28 PF04389.17 ORX91052.1 - 9.9e-38 129.8 0.0 1.5e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ORX91052.1 - 0.00032 19.8 0.0 0.0039 16.3 0.1 2.2 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORX91052.1 - 0.0006 19.6 0.1 0.0012 18.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 CRAL_TRIO PF00650.20 ORX91053.1 - 4.4e-40 137.0 0.0 2.2e-39 134.7 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX91053.1 - 1.1e-09 38.3 0.0 2.9e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORX91053.1 - 6.7e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Suc_Fer-like PF06999.12 ORX91054.1 - 1.4e-47 162.1 0.0 1.6e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Mss4 PF04421.13 ORX91054.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.5 1 1 0 1 1 1 0 Mss4 protein CIDE-N PF02017.15 ORX91054.1 - 0.045 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 CIDE-N domain zf-C2H2 PF00096.26 ORX91055.1 - 6.1e-11 42.2 12.0 2.8e-05 24.3 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX91055.1 - 5.1e-08 33.1 9.3 0.00026 21.5 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX91055.1 - 2.7e-07 30.7 3.0 2.7e-07 30.7 3.0 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX91055.1 - 5.8e-05 23.3 1.2 0.4 11.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX91055.1 - 0.0009 19.5 0.2 0.02 15.2 0.2 2.0 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORX91055.1 - 0.0023 18.2 2.1 0.22 11.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX91055.1 - 0.0025 17.8 0.8 0.0025 17.8 0.8 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORX91055.1 - 0.0047 17.1 1.8 0.35 11.0 0.1 2.0 2 0 0 2 2 2 2 Aberrant zinc-finger FOXP-CC PF16159.5 ORX91055.1 - 0.0052 17.4 0.6 3.2 8.5 0.0 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX91055.1 - 0.0066 17.1 3.3 0.014 16.1 3.3 1.6 1 1 0 1 1 1 1 TRAF-type zinc finger Ogr_Delta PF04606.12 ORX91055.1 - 0.039 14.0 1.8 2.4 8.2 0.1 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger CHORD PF04968.12 ORX91055.1 - 0.042 14.6 2.6 1.8 9.3 0.4 2.1 1 1 1 2 2 2 0 CHORD zf-C2HE PF16278.5 ORX91055.1 - 0.081 13.4 5.3 0.57 10.7 1.1 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 ORX91055.1 - 0.28 11.0 0.5 0.28 11.0 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Pkinase PF00069.25 ORX91057.1 - 5.3e-51 173.5 0.0 7.1e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91057.1 - 1e-30 106.9 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX91057.1 - 0.00034 20.0 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORX91057.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX91057.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1_Xtn PF16897.5 ORX91058.1 - 7.5e-43 144.9 0.7 2e-42 143.5 0.6 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORX91058.1 - 4.7e-22 77.8 0.1 8e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 ORX91058.1 - 1.8e-20 73.1 0.0 3.7e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX91058.1 - 2.5e-11 43.4 0.0 4.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORX91058.1 - 0.0062 16.6 0.2 1.6 8.8 0.0 2.5 1 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 ORX91058.1 - 0.034 14.5 0.0 0.063 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 ORX91058.1 - 0.061 13.6 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ORX91058.1 - 0.065 12.2 0.1 0.13 11.2 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ORX91058.1 - 0.066 13.5 0.1 0.23 11.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 ORX91058.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Haem_degrading PF03928.14 ORX91059.1 - 7.8e-34 116.3 0.0 9.1e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading Pkinase PF00069.25 ORX91060.1 - 1.2e-67 228.1 0.0 1.3e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91060.1 - 2.8e-33 115.3 0.0 3.3e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX91060.1 - 5.1e-06 25.7 0.0 7.1e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX91060.1 - 6.1e-06 25.8 0.1 2.1e-05 24.0 0.1 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORX91060.1 - 2.9e-05 24.1 0.1 0.0044 17.0 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX91060.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX91060.1 - 0.014 14.2 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ORX91060.1 - 0.033 13.8 0.1 4.6 6.8 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX91060.1 - 0.055 13.1 1.1 0.48 10.0 0.0 2.0 1 1 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 ORX91060.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Musclin PF11037.8 ORX91060.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle MgtE PF01769.16 ORX91062.1 - 2.7e-35 121.4 31.9 2.9e-22 79.4 7.7 3.2 3 0 0 3 3 3 2 Divalent cation transporter Ribosomal_L16 PF00252.18 ORX91063.1 - 3.2e-46 156.6 0.1 3.9e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ELO PF01151.18 ORX91064.1 - 7.5e-63 212.4 22.3 9.8e-63 212.0 22.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Stealth_CR2 PF11380.8 ORX91064.1 - 0.064 13.4 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 MFS_1 PF07690.16 ORX91067.1 - 2.3e-41 141.9 26.6 2.9e-41 141.6 26.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ORX91067.1 - 7.6 4.7 14.3 0.76 8.0 0.7 2.7 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-MIZ PF02891.20 ORX91068.1 - 4.8e-16 58.2 6.7 1.2e-15 56.9 6.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORX91068.1 - 7.2e-06 25.7 2.0 1.4e-05 24.8 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF155 PF02582.14 ORX91069.1 - 1.3e-54 184.9 0.7 2.3e-54 184.1 0.7 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF155 PF02582.14 ORX91070.1 - 7.6e-55 185.7 0.2 1.2e-54 185.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Glyco_H_20C_C PF18088.1 ORX91071.1 - 1.4e-50 171.9 0.1 2.6e-50 171.0 0.1 1.4 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 ORX91071.1 - 2.8e-10 40.1 0.0 7.7e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain AP_endonuc_2 PF01261.24 ORX91071.1 - 0.049 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel AA_permease PF00324.21 ORX91072.1 - 1.6e-130 436.0 45.9 1.9e-130 435.7 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX91072.1 - 6.7e-42 143.8 49.1 8.2e-42 143.5 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease HMG_box PF00505.19 ORX91073.1 - 1.8e-14 53.9 2.7 4.5e-14 52.6 2.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 ORX91073.1 - 6.9e-13 48.8 0.1 1.6e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 ORX91073.1 - 1e-09 38.8 2.4 1e-09 38.8 2.4 1.7 1 1 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 ORX91073.1 - 1.4e-09 37.9 0.1 3.3e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORX91073.1 - 0.0049 16.8 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) DUF3919 PF13057.6 ORX91073.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DNA_pol3_a_NII PF11490.8 ORX91073.1 - 0.79 9.6 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Proteasome PF00227.26 ORX91074.1 - 3.8e-48 163.5 0.1 4.5e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit UQ_con PF00179.26 ORX91075.1 - 2.6e-51 172.9 0.0 3e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CAF1C_H4-bd PF12265.8 ORX91076.1 - 6e-29 100.1 0.4 4e-28 97.5 0.4 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORX91076.1 - 3.3e-25 87.8 12.1 3e-05 24.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91076.1 - 1.1e-05 25.6 1.7 0.073 13.4 0.0 4.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91076.1 - 0.00012 22.0 0.8 0.00063 19.7 0.0 2.5 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Glycogen_syn PF05693.13 ORX91077.1 - 0 1109.5 0.0 0 1109.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 ORX91077.1 - 2.6e-06 27.3 0.1 7e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 ORX91077.1 - 4.8e-06 26.2 0.0 7.9e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX91077.1 - 2.3e-05 24.8 0.0 0.0034 17.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORX91077.1 - 2.4e-05 24.4 0.2 4.9e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORX91077.1 - 0.00056 20.4 0.0 0.0015 19.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain HLH PF00010.26 ORX91078.1 - 5.3e-12 45.5 0.2 1e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.9 ORX91078.1 - 0.016 15.5 2.1 0.03 14.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) HALZ PF02183.18 ORX91078.1 - 0.016 15.4 0.7 0.029 14.6 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 ORX91078.1 - 0.017 15.2 2.2 0.021 14.9 0.5 1.8 2 0 0 2 2 2 0 bZIP transcription factor Fungal_TACC PF12709.7 ORX91078.1 - 0.043 14.3 0.1 0.087 13.3 0.1 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2381 PF09544.10 ORX91078.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) K-box PF01486.17 ORX91078.1 - 0.11 12.7 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 K-box region bZIP_2 PF07716.15 ORX91078.1 - 6 7.0 7.5 0.25 11.4 1.4 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 ORX91079.1 - 1.6e-44 152.3 0.0 3.4e-29 102.0 0.1 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91079.1 - 1.1e-31 110.0 0.0 1.3e-18 67.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase DUF1241 PF06840.11 ORX91079.1 - 1.5e-05 24.7 0.1 2.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Csm1_N PF18504.1 ORX91079.1 - 0.071 13.5 0.4 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain PBD PF00786.28 ORX91080.1 - 0.00021 21.6 0.7 0.00032 21.0 0.5 1.6 1 1 0 1 1 1 1 P21-Rho-binding domain PITH PF06201.13 ORX91081.1 - 8.5e-40 136.4 5.7 8.5e-40 136.4 5.7 1.8 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 ORX91081.1 - 5.7e-25 87.3 0.3 1.5e-24 86.0 0.3 1.7 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORX91081.1 - 2e-07 30.7 0.2 3.6e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORX91081.1 - 2.7e-05 24.5 2.4 0.00023 21.6 0.8 2.7 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORX91081.1 - 0.00035 20.8 0.3 0.00095 19.5 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ORX91081.1 - 0.0026 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 ORX91081.1 - 0.0037 17.0 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 ORX91081.1 - 0.0049 16.8 0.2 0.012 15.6 0.2 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ORX91081.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like WES_acyltransf PF03007.16 ORX91081.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain WD40 PF00400.32 ORX91082.1 - 2.6e-23 81.9 9.2 0.00013 22.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91082.1 - 1.2e-06 28.7 0.2 0.0025 18.1 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 ORX91083.1 - 6.3e-20 70.6 0.1 7.1e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX91083.1 - 3.1e-06 27.2 0.0 3.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORX91083.1 - 0.0082 16.2 0.1 0.0092 16.1 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain ELK PF03789.13 ORX91083.1 - 0.37 10.9 1.4 22 5.3 0.1 2.4 2 0 0 2 2 2 0 ELK domain BolA PF01722.18 ORX91084.1 - 1.5e-13 50.8 0.1 3.4e-13 49.7 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein Cons_hypoth95 PF03602.15 ORX91084.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Fibrillarin PF01269.17 ORX91084.1 - 0.032 13.4 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin HSF_DNA-bind PF00447.17 ORX91085.1 - 1.4e-31 109.0 3.5 1.4e-31 109.0 3.5 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 ORX91085.1 - 3.8e-24 85.0 0.1 1.1e-23 83.6 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain RPAP1_C PF08620.10 ORX91086.1 - 5.1e-26 90.6 0.0 1e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 ORX91086.1 - 1.5e-14 53.5 5.7 6.5e-14 51.4 5.7 2.2 1 0 0 1 1 1 1 RPAP1-like, N-terminal SRF-TF PF00319.18 ORX91087.1 - 1.6e-21 75.5 0.1 2.1e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3931 PF13082.6 ORX91087.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) DUF5600 PF18150.1 ORX91088.1 - 3.1e-41 140.3 1.2 6.6e-41 139.2 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 ORX91088.1 - 8e-15 55.3 0.0 4.7e-13 49.5 0.0 2.6 2 1 0 2 2 2 1 Dynamin family EF-hand_4 PF12763.7 ORX91088.1 - 5.4e-14 52.0 0.0 1.8e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 ORX91088.1 - 2.7e-13 49.5 0.4 3.1e-12 46.1 0.0 2.5 2 0 0 2 2 2 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 ORX91088.1 - 1.4e-08 34.8 0.0 4e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 ORX91088.1 - 2.7e-05 23.4 0.0 7.9e-05 21.9 0.0 1.9 1 0 0 1 1 1 1 EF hand GTP_EFTU PF00009.27 ORX91088.1 - 8.1e-05 22.2 0.0 0.00023 20.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 ORX91088.1 - 0.00017 21.8 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 ORX91088.1 - 0.0015 18.0 0.0 0.079 12.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 ORX91088.1 - 0.0036 16.7 0.0 0.0069 15.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.6 ORX91088.1 - 0.025 14.5 0.0 0.087 12.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain SRPRB PF09439.10 ORX91088.1 - 0.04 13.3 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PIN_5 PF08745.11 ORX91088.1 - 0.08 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 PINc domain ribonuclease AAA_3 PF07726.11 ORX91088.1 - 0.098 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 ORX91088.1 - 0.14 11.5 0.0 0.51 9.6 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Ras PF00071.22 ORX91088.1 - 0.15 11.7 0.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Ras family EF-hand_8 PF13833.6 ORX91088.1 - 0.16 11.8 0.1 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair NAD_binding_10 PF13460.6 ORX91089.1 - 4.2e-14 52.8 0.0 6.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX91089.1 - 1.3e-10 41.2 0.1 2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ORX91089.1 - 8.1e-08 31.6 0.0 2.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX91089.1 - 6.5e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORX91089.1 - 2.2e-06 27.0 0.0 5.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 ORX91089.1 - 0.0014 19.1 0.1 0.0026 18.2 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX91089.1 - 0.003 17.8 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain S6PP PF05116.13 ORX91089.1 - 0.023 14.3 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Polysacc_synt_2 PF02719.15 ORX91089.1 - 0.028 13.6 0.1 0.069 12.3 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 ORX91089.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ORX91089.1 - 0.11 13.2 0.1 0.21 12.3 0.1 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GRP PF07172.11 ORX91092.1 - 5.2 7.8 24.6 4 8.2 22.8 1.6 1 1 1 2 2 2 0 Glycine rich protein family NAD_binding_10 PF13460.6 ORX91096.1 - 1.9e-14 54.0 0.1 2.5e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX91096.1 - 4.8e-10 39.4 0.1 7.4e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ORX91096.1 - 3.4e-07 29.5 0.0 0.00032 19.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX91096.1 - 1.6e-06 27.5 0.0 5.6e-06 25.7 0.0 2.0 3 0 0 3 3 3 1 Male sterility protein Epimerase PF01370.21 ORX91096.1 - 1.7e-06 27.7 0.0 4.7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORX91096.1 - 0.00047 20.6 0.0 0.00087 19.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX91096.1 - 0.016 15.4 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 ORX91096.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ORX91096.1 - 0.066 13.9 0.0 0.18 12.5 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TM1506 PF08973.10 ORX91096.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) Lipase_3 PF01764.25 ORX91097.1 - 1.7e-19 70.1 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX91097.1 - 0.0046 17.6 0.0 0.0082 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 ORX91098.1 - 2e-19 69.9 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX91098.1 - 0.0033 18.0 0.0 0.0059 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S30 PF04758.14 ORX91100.1 - 5.7e-29 100.1 6.2 6.2e-29 100.0 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF3408 PF11888.8 ORX91100.1 - 0.016 15.4 1.6 0.018 15.2 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Kinesin PF00225.23 ORX91101.1 - 2.9e-109 365.0 1.1 5.3e-109 364.2 1.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 ORX91101.1 - 1.2e-42 146.2 0.4 4.4e-42 144.4 0.4 2.1 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 ORX91101.1 - 9.6e-42 143.2 16.8 1.7e-34 119.6 0.5 4.3 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 ORX91101.1 - 1.4e-21 77.0 0.2 4e-21 75.5 0.2 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 ORX91101.1 - 1.5e-14 54.4 0.3 1e-13 51.7 0.4 2.4 2 0 0 2 2 2 1 PH domain FHA PF00498.26 ORX91101.1 - 1.9e-07 31.3 0.1 1.8e-06 28.2 0.0 2.8 3 0 0 3 3 2 1 FHA domain KIF1B PF12423.8 ORX91101.1 - 3.8e-06 27.2 0.1 1.3e-05 25.5 0.1 2.0 1 0 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 ORX91101.1 - 6e-05 23.3 0.0 0.00019 21.7 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH_9 PF15410.6 ORX91101.1 - 0.00024 21.5 0.6 0.0012 19.2 0.6 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain Exonuc_VII_L PF02601.15 ORX91101.1 - 0.067 12.7 8.8 2 7.9 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tox-URI2 PF15653.6 ORX91101.1 - 0.64 10.3 3.9 12 6.2 0.1 2.7 2 0 0 2 2 2 0 URI fold toxin 2 DUF4854 PF16146.5 ORX91101.1 - 0.77 10.1 7.9 0.34 11.2 4.0 2.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4854) HalX PF08663.10 ORX91101.1 - 4.6 7.6 10.1 2.9 8.3 5.7 2.7 2 0 0 2 2 2 0 HalX domain Vir_act_alpha_C PF10400.9 ORX91101.1 - 8.7 7.1 16.3 6.8 7.4 1.3 4.5 2 2 0 2 2 2 0 Virulence activator alpha C-term Nup88 PF10168.9 ORX91102.1 - 9.9e-57 192.2 0.7 3.2e-34 117.8 1.0 2.1 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 ORX91102.1 - 7.9e-07 29.3 3.3 2.1e-06 27.9 3.3 1.8 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 TIP120 PF08623.10 ORX91102.1 - 0.0027 17.5 2.4 0.0064 16.3 2.4 1.6 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) DUF2959 PF11172.8 ORX91102.1 - 0.04 14.1 1.7 0.49 10.5 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) ABC_tran_CTD PF16326.5 ORX91102.1 - 0.081 13.2 0.2 0.081 13.2 0.2 3.7 3 1 1 4 4 4 0 ABC transporter C-terminal domain Apolipoprotein PF01442.18 ORX91102.1 - 0.34 10.8 5.5 0.71 9.7 5.5 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 ORX91102.1 - 0.57 9.5 3.0 1.1 8.6 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Allexi_40kDa PF05549.11 ORX91102.1 - 1 8.8 5.3 1.8 8.0 4.4 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein Exonuc_VII_L PF02601.15 ORX91102.1 - 2.9 7.4 6.8 5.7 6.4 6.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 ORX91102.1 - 4.1 7.9 11.6 0.62 10.5 4.5 3.2 2 1 0 2 2 2 0 Snapin/Pallidin Cir_N PF10197.9 ORX91102.1 - 5.2 7.3 10.3 0.67 10.2 4.6 2.5 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR HIP1_clath_bdg PF16515.5 ORX91102.1 - 5.8 7.6 9.4 6 7.5 0.8 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_L1 PF00687.21 ORX91103.1 - 1.5e-31 109.8 0.1 2.1e-31 109.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Metallophos PF00149.28 ORX91104.1 - 3.8e-35 122.3 0.4 5.2e-35 121.8 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX91104.1 - 0.021 15.0 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HLH PF00010.26 ORX91105.1 - 1.8e-15 56.6 1.5 3.7e-15 55.6 1.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 ORX91105.1 - 0.15 11.8 0.4 0.15 11.8 0.4 1.6 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.32 ORX91111.1 - 1.7e-18 66.6 2.8 1.2e-05 25.9 0.6 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91111.1 - 1.3e-12 47.8 0.3 8.9e-08 32.3 0.1 3.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91111.1 - 0.00064 19.6 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX91111.1 - 0.004 16.1 0.3 0.24 10.3 0.0 2.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX91111.1 - 0.0089 14.7 0.1 0.016 13.9 0.1 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Frtz PF11768.8 ORX91111.1 - 0.027 12.8 0.0 0.11 10.8 0.0 1.9 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 ORX91111.1 - 0.12 11.7 0.0 0.52 9.6 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain DUF3510 PF12022.8 ORX91112.1 - 8.1e-34 116.7 0.1 8.1e-34 116.7 0.1 3.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3510) COG2 PF06148.11 ORX91112.1 - 7.1e-22 77.9 5.7 7.1e-22 77.9 5.7 3.7 5 0 0 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 HTH_40 PF14493.6 ORX91112.1 - 0.0086 16.5 1.7 0.023 15.1 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain PDCD2_C PF04194.13 ORX91112.1 - 0.12 12.5 0.4 0.35 10.9 0.4 1.8 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Tctex-1 PF03645.13 ORX91112.1 - 0.13 12.5 0.9 12 6.2 0.0 3.1 3 0 0 3 3 3 0 Tctex-1 family Phage_X PF05155.15 ORX91112.1 - 0.14 12.6 0.0 0.48 10.9 0.0 2.0 1 0 0 1 1 1 0 Phage X family Tyrosinase PF00264.20 ORX91113.1 - 6.6e-37 127.9 3.5 4.1e-36 125.3 3.5 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase WD40 PF00400.32 ORX91114.1 - 1e-16 61.0 20.9 0.001 19.8 0.1 9.3 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91114.1 - 1.1e-16 60.8 0.1 0.003 17.8 0.0 7.9 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX91114.1 - 0.0002 20.4 0.0 1.1 8.1 0.0 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORX91114.1 - 0.0032 15.8 0.0 0.0075 14.6 0.0 1.5 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 ORX91114.1 - 0.014 15.4 0.4 43 4.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF2048 PF09752.9 ORX91114.1 - 0.058 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Histone PF00125.24 ORX91115.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX91115.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX91115.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORX91115.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORX91115.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX91115.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX91115.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Aconitase PF00330.20 ORX91117.1 - 2.1e-153 511.6 0.0 2.6e-153 511.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX91117.1 - 1.2e-44 151.8 0.0 2.4e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RabGAP-TBC PF00566.18 ORX91118.1 - 3.1e-50 170.8 4.6 4.2e-50 170.4 4.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glutaredoxin PF00462.24 ORX91119.1 - 8.1e-16 58.0 0.0 1.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin LETM1 PF07766.13 ORX91120.1 - 5.5e-103 344.0 3.7 5.5e-103 344.0 3.7 2.1 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 ORX91120.1 - 0.042 13.6 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 SAP domain V_ATPase_I PF01496.19 ORX91120.1 - 0.49 8.2 7.2 1.2 7.0 0.1 2.9 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family FAD_binding_2 PF00890.24 ORX91122.1 - 2e-84 284.1 1.4 2.3e-84 283.9 1.4 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX91122.1 - 4.1e-12 46.4 3.7 3.3e-11 43.4 3.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORX91122.1 - 9.9e-11 41.6 0.1 1.5e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX91122.1 - 1e-08 35.3 0.2 2.7e-08 33.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORX91122.1 - 3e-08 33.3 0.3 4.6e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX91122.1 - 6e-06 25.7 3.4 0.00079 18.8 3.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORX91122.1 - 1.5e-05 24.5 0.6 0.0058 16.0 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORX91122.1 - 4.1e-05 22.5 4.3 0.00036 19.4 0.6 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 ORX91122.1 - 0.00022 20.4 6.6 0.0011 18.1 2.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 ORX91122.1 - 0.00024 20.4 0.7 0.0031 16.8 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ORX91122.1 - 0.0049 17.4 2.0 1.2 9.7 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX91122.1 - 0.011 14.9 0.2 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORX91122.1 - 0.014 14.7 0.5 0.039 13.3 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ORX91122.1 - 0.022 13.8 0.9 0.033 13.3 0.9 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ORX91122.1 - 0.07 12.0 1.8 0.23 10.2 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase V_ATPase_I PF01496.19 ORX91125.1 - 0 1052.5 0.2 0 1052.3 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1471 PF07338.13 ORX91125.1 - 0.0011 18.9 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1471) Pkinase PF00069.25 ORX91126.1 - 1.5e-15 57.3 0.6 1.6e-14 54.0 0.6 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91126.1 - 4.8e-09 35.9 0.4 2.5e-05 23.7 0.3 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX91126.1 - 3.8e-05 22.7 0.2 5.1e-05 22.2 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORX91126.1 - 0.0009 18.7 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX91126.1 - 0.0042 16.7 0.7 0.0069 16.0 0.7 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORX91126.1 - 0.017 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CH PF00307.31 ORX91127.1 - 6e-35 119.7 0.0 2.5e-16 59.8 0.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.17 ORX91127.1 - 5.5e-11 42.4 0.0 1.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.21 ORX91127.1 - 4.6e-05 23.9 1.2 0.00049 20.6 0.4 12.1 12 2 2 14 14 14 3 Spectrin repeat CAMSAP_CH PF11971.8 ORX91127.1 - 0.023 14.5 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain Bap31_Bap29_C PF18035.1 ORX91127.1 - 0.15 12.1 2.7 9.1 6.4 0.4 3.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Sugarporin_N PF11471.8 ORX91127.1 - 0.3 11.1 3.5 4.8 7.2 0.1 4.0 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension SCAPER_N PF16501.5 ORX91127.1 - 1 9.4 4.6 0.86 9.7 0.2 3.2 3 0 0 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum DUF2205 PF10224.9 ORX91127.1 - 5.4 7.1 10.3 0.37 10.8 0.6 4.3 5 0 0 5 5 5 0 Short coiled-coil protein TruD PF01142.18 ORX91128.1 - 7.4e-76 255.6 0.0 1e-75 255.2 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Fungal_trans PF04082.18 ORX91129.1 - 8.4e-32 110.3 0.0 1.4e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX91129.1 - 1.1e-11 44.7 12.1 2.1e-11 43.8 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORX91130.1 - 1.3e-77 260.7 0.0 1.7e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91130.1 - 7.2e-36 123.8 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORX91130.1 - 9.4e-19 67.5 0.4 2.1e-18 66.4 0.4 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 ORX91130.1 - 3.1e-08 33.3 0.0 2.8e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 ORX91130.1 - 4.6e-05 23.7 0.0 0.00019 21.7 0.0 2.0 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 ORX91130.1 - 0.00098 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX91130.1 - 0.0013 17.6 0.0 0.0028 16.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX91130.1 - 0.0041 17.1 0.0 0.28 11.1 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORX91130.1 - 0.051 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_C48 PF02902.19 ORX91131.1 - 1.9e-09 37.7 0.1 2.2e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GFO_IDH_MocA_C PF02894.17 ORX91131.1 - 0.016 15.2 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Pyridoxal_deC PF00282.19 ORX91134.1 - 4.3e-50 170.5 0.0 5.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ORX91134.1 - 0.00019 20.8 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 ORX91134.1 - 0.0023 16.7 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS BRK PF07533.16 ORX91134.1 - 0.011 15.3 0.1 0.028 14.0 0.1 1.7 1 0 0 1 1 1 0 BRK domain Aminotran_5 PF00266.19 ORX91134.1 - 0.025 13.5 0.0 0.067 12.1 0.0 1.6 1 1 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORX91134.1 - 0.072 12.2 0.0 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II Se-cys_synth_N PF12390.8 ORX91134.1 - 0.8 10.0 2.7 1.9 8.8 0.1 2.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal GMC_oxred_N PF00732.19 ORX91135.1 - 1.1e-30 107.1 0.0 2.7e-30 105.8 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX91135.1 - 1.4e-28 100.2 0.0 2.5e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORX91135.1 - 2e-06 27.2 0.1 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORX91135.1 - 4.5e-05 23.6 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX91135.1 - 0.00031 20.1 0.1 0.00099 18.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX91135.1 - 0.00059 19.5 0.0 0.0056 16.3 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX91135.1 - 0.0029 16.9 1.6 1.7 7.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX91135.1 - 0.042 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 ORX91135.1 - 0.049 12.7 2.8 0.35 9.9 0.6 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORX91135.1 - 0.091 12.0 0.3 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 ORX91135.1 - 0.091 12.1 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 ORX91135.1 - 0.15 10.7 0.2 0.32 9.6 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 ORX91135.1 - 0.18 11.5 0.2 0.36 10.5 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ORX91135.1 - 0.23 10.7 1.6 0.35 10.2 1.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase CotH PF08757.11 ORX91136.1 - 1e-42 146.8 0.3 1.4e-42 146.4 0.3 1.1 1 0 0 1 1 1 1 CotH kinase protein NOT2_3_5 PF04153.18 ORX91137.1 - 1.3e-33 115.8 0.2 1.7e-33 115.5 0.2 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cytadhesin_P30 PF07271.11 ORX91137.1 - 0.41 10.2 2.6 0.63 9.6 2.6 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 GDPD PF03009.17 ORX91143.1 - 1.4e-30 106.9 0.0 1e-28 100.8 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CDC50 PF03381.15 ORX91145.1 - 5e-98 328.1 0.0 6e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family GPI-anchored PF10342.9 ORX91146.1 - 1.5e-13 51.3 0.6 3.4e-13 50.2 0.0 1.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sporozoite_P67 PF05642.11 ORX91146.1 - 8.4 4.3 12.9 10 4.0 12.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GPI-anchored PF10342.9 ORX91147.1 - 7.3e-14 52.3 1.7 1.2e-13 51.7 0.0 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORX91148.1 - 2.1e-14 54.0 0.2 6.5e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LPMO_10 PF03067.15 ORX91149.1 - 2.4e-06 28.3 0.0 3.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX91149.1 - 0.0007 19.6 0.1 0.0077 16.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 PapD_C PF02753.17 ORX91149.1 - 0.058 13.8 0.0 6.5 7.2 0.0 2.7 2 1 1 3 3 3 0 Pili assembly chaperone PapD, C-terminal domain MelC1 PF06236.11 ORX91149.1 - 0.069 13.2 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF4625 PF15418.6 ORX91149.1 - 0.18 12.0 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) HAGH_C PF16123.5 ORX91150.1 - 1.9e-26 92.4 0.1 5.1e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORX91150.1 - 4.3e-13 49.7 0.5 4.7e-12 46.3 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX91150.1 - 0.0012 18.4 0.1 0.006 16.1 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORX91150.1 - 0.038 13.9 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RGS PF00615.19 ORX91151.1 - 5.6e-08 33.1 0.1 7.4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rad51 PF08423.11 ORX91152.1 - 0.00048 19.5 0.0 0.00061 19.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 Arrestin_C PF02752.22 ORX91153.1 - 1.1e-05 25.9 0.2 0.0072 16.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX91153.1 - 0.045 13.8 0.4 1 9.4 0.1 2.8 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DNA_pol_B PF00136.21 ORX91154.1 - 3.7e-125 418.2 0.0 7.1e-125 417.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 ORX91154.1 - 5.8e-56 189.2 4.0 1.5e-55 187.8 4.0 1.8 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 ORX91154.1 - 3.4e-49 167.8 0.1 7.3e-49 166.7 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 ORX91154.1 - 1.4e-21 76.3 7.7 5e-21 74.5 7.7 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Cdc6_C PF09079.11 ORX91154.1 - 0.023 14.7 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DNA_pol_B_exo2 PF10108.9 ORX91154.1 - 0.1 12.3 0.3 0.88 9.2 0.0 2.5 3 0 0 3 3 3 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF498 PF04430.14 ORX91155.1 - 1.4e-30 105.5 0.0 1.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) PCNA_N PF00705.18 ORX91156.1 - 9.8e-59 196.6 1.7 1.3e-58 196.2 0.9 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORX91156.1 - 1.5e-45 154.5 0.1 3.3e-45 153.4 0.1 1.6 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 ORX91156.1 - 8.1e-09 35.3 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 ORX91156.1 - 1.7e-05 24.0 0.2 0.00036 19.7 0.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 ORX91156.1 - 0.062 12.4 0.0 0.19 10.8 0.0 1.8 1 1 0 1 1 1 0 Hus1-like protein PCNA_N PF00705.18 ORX91157.1 - 6.2e-59 197.2 1.8 1.4e-58 196.1 0.9 1.9 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORX91157.1 - 2e-58 196.1 0.1 3.1e-58 195.5 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 ORX91157.1 - 4.3e-09 35.8 0.5 9.1e-08 31.5 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 ORX91157.1 - 2.2e-08 33.9 0.0 2.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 ORX91157.1 - 0.04 13.0 0.0 0.16 11.1 0.0 2.1 1 1 0 1 1 1 0 Hus1-like protein RsfS PF02410.15 ORX91158.1 - 4.8e-27 94.3 0.5 8.4e-27 93.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF2470 PF10615.9 ORX91158.1 - 0.14 12.8 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) LPMO_10 PF03067.15 ORX91159.1 - 0.0014 19.3 0.7 0.2 12.3 0.3 2.1 1 1 1 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX91159.1 - 0.0081 16.1 0.0 0.0092 15.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX91160.1 - 1.3e-11 45.5 6.7 1.3e-10 42.3 3.9 2.3 1 1 1 2 2 2 2 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX91160.1 - 0.00033 20.6 1.7 0.0066 16.4 1.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 GPI-anchored PF10342.9 ORX91160.1 - 0.044 14.5 0.1 0.082 13.7 0.1 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family adh_short PF00106.25 ORX91161.1 - 3.2e-48 163.8 0.9 5.2e-48 163.1 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX91161.1 - 2.3e-33 115.7 0.4 2.7e-33 115.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX91161.1 - 2.8e-11 43.7 0.2 3.7e-11 43.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX91161.1 - 5.2e-05 22.5 0.4 7.8e-05 21.9 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORX91161.1 - 0.00018 21.0 0.3 0.001 18.6 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX91161.1 - 0.00078 18.9 0.1 0.003 17.0 0.1 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 ORX91161.1 - 0.011 15.9 1.3 0.016 15.4 0.4 1.7 2 0 0 2 2 2 0 TrkA-N domain GST_C_3 PF14497.6 ORX91162.1 - 2e-10 40.7 0.0 4.6e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX91162.1 - 2e-09 37.5 0.0 3.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX91162.1 - 8.9e-09 35.3 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX91162.1 - 2.7e-08 34.1 0.0 5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORX91162.1 - 2.2e-06 27.9 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX91162.1 - 0.008 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C2H2 PF00096.26 ORX91163.1 - 3.4e-11 43.0 28.8 0.00049 20.4 0.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX91163.1 - 4.4e-11 42.7 14.4 1.4e-09 37.9 1.3 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX91163.1 - 1.3e-06 28.7 24.4 0.017 15.9 0.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX91163.1 - 9e-05 22.4 0.1 9e-05 22.4 0.1 3.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX91163.1 - 0.0013 19.0 14.6 0.55 10.6 0.0 3.2 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORX91163.1 - 0.0029 17.5 0.2 0.0029 17.5 0.2 2.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORX91163.1 - 0.077 12.8 0.1 0.077 12.8 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 ORX91163.1 - 0.096 13.1 16.2 0.78 10.2 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 ORX91163.1 - 0.11 12.6 1.7 3.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 ORX91163.1 - 0.18 11.9 11.4 10 6.3 0.2 3.1 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 ORX91163.1 - 0.26 11.6 11.8 1.7 9.0 7.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 ORX91163.1 - 0.4 10.8 4.8 3 8.0 0.3 2.3 1 1 2 3 3 3 0 Zinc ribbon domain GAGA PF09237.11 ORX91163.1 - 1.5 8.7 9.1 0.25 11.2 5.4 1.8 1 1 1 2 2 2 0 GAGA factor FYVE PF01363.21 ORX91163.1 - 2.9 8.1 12.7 1.8 8.7 9.7 2.0 1 1 1 2 2 2 0 FYVE zinc finger CHDCT2 PF08074.11 ORX91164.1 - 0.021 15.0 0.7 0.031 14.5 0.7 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF4164 PF13747.6 ORX91164.1 - 0.089 13.1 6.9 0.16 12.3 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) bZIP_2 PF07716.15 ORX91164.1 - 0.16 12.0 10.8 0.81 9.8 0.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 ORX91164.1 - 1.3 9.4 6.7 4.5 7.7 1.5 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family WD40_alt PF14077.6 ORX91164.1 - 9.5 6.2 10.5 0.33 10.9 1.2 2.5 2 1 1 3 3 3 0 Alternative WD40 repeat motif Aminotran_5 PF00266.19 ORX91166.1 - 5.6e-34 117.7 0.0 7.2e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORX91166.1 - 0.00029 19.5 0.0 0.00046 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 ORX91166.1 - 0.15 12.1 0.4 0.98 9.5 0.1 2.2 2 0 0 2 2 2 0 B12 binding domain ADH_zinc_N PF00107.26 ORX91168.1 - 1.8e-18 66.7 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX91168.1 - 3.5e-06 28.1 0.0 9.7e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX91168.1 - 0.00037 20.4 0.0 0.00087 19.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 ORX91168.1 - 0.024 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family PCMT PF01135.19 ORX91168.1 - 0.09 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MCM_bind PF09739.9 ORX91169.1 - 2.5e-113 379.6 1.0 9.2e-88 295.2 0.1 2.1 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Zn_ribbon_2 PF12674.7 ORX91170.1 - 0.52 11.0 9.8 0.12 13.0 2.4 2.6 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-HIT PF04438.16 ORX91170.1 - 6.9 6.6 10.4 20 5.2 10.3 1.8 1 1 1 2 2 2 0 HIT zinc finger TFIIF_beta PF02270.15 ORX91171.1 - 4.1e-26 90.9 0.1 6.6e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 ORX91171.1 - 4.3e-25 89.0 0.3 3.7e-23 82.7 0.0 2.4 1 1 1 2 2 2 2 TFIIF, beta subunit N-terminus Tau95 PF09734.9 ORX91171.1 - 0.0098 16.7 0.1 0.017 15.9 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain NIF3 PF01784.18 ORX91172.1 - 2.9e-48 164.6 0.0 3.5e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Methyltransf_16 PF10294.9 ORX91173.1 - 8.6e-32 110.3 0.2 1.1e-31 110.0 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MethyltransfD12 PF02086.15 ORX91173.1 - 0.033 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.14 ORX91173.1 - 0.067 12.7 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Fcf2 PF08698.11 ORX91174.1 - 9.8e-42 141.3 0.5 3e-41 139.7 0.5 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing NDUFB10 PF10249.9 ORX91175.1 - 4.9e-07 30.3 0.9 5.8e-07 30.1 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF3517 PF12030.8 ORX91175.1 - 0.012 14.5 0.2 0.015 14.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Ret2_MD PF18528.1 ORX91175.1 - 0.12 12.8 0.8 0.18 12.2 0.8 1.2 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain RRP36 PF06102.12 ORX91176.1 - 6e-49 166.2 25.3 6.9e-49 166.0 25.3 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 AAA_8 PF12780.7 ORX91176.1 - 0.0073 15.7 0.7 0.01 15.2 0.7 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 FlxA PF14282.6 ORX91176.1 - 0.021 14.8 7.0 0.042 13.8 7.0 1.5 1 0 0 1 1 1 0 FlxA-like protein Cons_hypoth95 PF03602.15 ORX91176.1 - 0.079 12.6 3.1 0.099 12.3 3.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MapZ_EC1 PF18041.1 ORX91176.1 - 1.9 8.7 11.5 0.093 13.0 2.2 2.2 1 1 1 2 2 2 0 MapZ extracellular domain 1 VanZ PF04892.12 ORX91177.1 - 3e-07 31.1 3.9 5.7e-07 30.2 3.9 1.5 1 1 0 1 1 1 1 VanZ like family EII-Sor PF03609.14 ORX91177.1 - 0.062 12.7 2.3 0.094 12.1 2.2 1.4 1 1 0 1 1 1 0 PTS system sorbose-specific iic component DUF2279 PF10043.9 ORX91177.1 - 0.086 13.6 0.0 0.12 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) DUF1077 PF06417.12 ORX91177.1 - 0.11 12.5 0.6 0.14 12.2 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1077) EMP24_GP25L PF01105.24 ORX91178.1 - 4.5e-44 150.6 0.1 5.4e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COX4 PF02936.14 ORX91179.1 - 1.6e-35 122.1 0.1 2.3e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.10 ORX91179.1 - 0.013 15.5 0.5 0.067 13.2 0.0 2.2 2 1 1 3 3 3 0 Putative addiction module component HIG_1_N PF04588.13 ORX91180.1 - 1e-06 28.9 3.6 1e-06 28.9 3.6 2.5 2 1 0 2 2 2 1 Hypoxia induced protein conserved region XhoI PF04555.13 ORX91180.1 - 0.081 12.8 0.3 10 6.0 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease XhoI DnaJ PF00226.31 ORX91181.1 - 5.1e-10 39.3 0.2 5.1e-10 39.3 0.2 2.4 3 0 0 3 3 3 1 DnaJ domain DUF3959 PF13105.6 ORX91181.1 - 0.39 10.2 4.2 0.53 9.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Trypsin PF00089.26 ORX91182.1 - 3.4e-28 99.0 0.0 4.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX91182.1 - 0.0039 18.1 0.0 0.006 17.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain TPR_19 PF14559.6 ORX91183.1 - 6.8e-14 52.1 0.2 1.2e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX91183.1 - 7.3e-08 32.0 0.0 0.0066 16.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX91183.1 - 2.1e-07 31.0 0.1 1.6e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORX91183.1 - 1.5e-06 28.5 0.0 0.051 14.4 0.1 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX91183.1 - 4.8e-06 26.4 0.0 0.047 13.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORX91183.1 - 7.2e-06 26.3 0.1 8.3 7.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX91183.1 - 7.3e-06 26.0 0.1 0.31 11.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX91183.1 - 1.2e-05 25.4 0.0 0.03 14.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX91183.1 - 2.1e-05 24.7 0.1 0.25 11.7 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX91183.1 - 0.00017 21.3 0.0 0.16 11.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX91183.1 - 0.00038 20.1 0.1 0.72 9.6 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_MalT PF17874.1 ORX91183.1 - 0.0045 16.4 0.0 0.024 14.0 0.0 2.0 1 1 1 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 ORX91183.1 - 0.057 13.5 0.0 7.4 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORX91183.1 - 0.059 12.6 0.3 0.1 11.8 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORX91183.1 - 0.092 12.4 0.3 1 9.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 ORX91183.1 - 0.15 11.8 0.5 0.25 11.0 0.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Velvet PF11754.8 ORX91184.1 - 8.4e-33 114.3 0.1 9.6e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Velvet factor Isochorismatase PF00857.20 ORX91193.1 - 4.4e-23 82.4 0.0 8.6e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family zf-ZPR1 PF03367.13 ORX91193.1 - 0.019 14.8 0.1 0.069 13.0 0.0 1.8 1 1 0 2 2 2 0 ZPR1 zinc-finger domain Glyco_trans_4_2 PF13477.6 ORX91193.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like Hist_deacetyl PF00850.19 ORX91194.1 - 3.4e-50 171.3 0.8 5.4e-32 111.5 0.0 2.3 1 1 1 2 2 2 2 Histone deacetylase domain Arb2 PF09757.9 ORX91194.1 - 2.4e-17 62.9 0.1 4.1e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain TIP120 PF08623.10 ORX91195.1 - 2.8e-60 202.9 1.0 2.8e-60 202.9 1.0 4.7 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 ORX91195.1 - 1.4e-19 70.2 12.1 0.027 15.0 0.0 12.0 11 2 2 13 13 13 3 HEAT-like repeat HEAT_2 PF13646.6 ORX91195.1 - 1.1e-15 57.8 3.7 0.021 15.2 0.0 8.6 6 3 2 9 9 9 2 HEAT repeats HEAT PF02985.22 ORX91195.1 - 2e-13 49.3 19.2 0.28 11.5 0.0 12.2 13 0 0 13 13 11 2 HEAT repeat Cnd1 PF12717.7 ORX91195.1 - 2.7e-08 34.0 29.2 0.0098 15.9 1.4 8.5 6 4 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORX91195.1 - 3.6e-06 27.5 5.4 0.91 10.2 0.1 7.4 8 1 1 9 9 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 ORX91195.1 - 5.4e-06 26.1 5.8 1.6 8.2 0.5 5.2 4 1 0 5 5 5 3 CLASP N terminal V-ATPase_H_C PF11698.8 ORX91195.1 - 0.00021 21.4 12.1 0.22 11.7 0.5 6.9 7 0 0 7 7 6 1 V-ATPase subunit H Proteasom_PSMB PF10508.9 ORX91195.1 - 0.00021 19.9 1.9 0.00021 19.9 1.9 4.2 5 1 1 6 6 6 1 Proteasome non-ATPase 26S subunit UME PF08064.13 ORX91195.1 - 0.0017 18.3 5.5 5.5 7.0 0.0 6.7 5 1 2 7 7 7 1 UME (NUC010) domain HEAT_UF PF18817.1 ORX91195.1 - 0.0029 17.9 1.3 11 6.4 0.0 4.9 5 0 0 5 5 4 0 Repeat of uncharacterized protein PH0542 RTP1_C1 PF10363.9 ORX91195.1 - 0.0053 16.9 10.3 0.73 10.0 0.1 7.0 7 0 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 CsgA PF17334.2 ORX91195.1 - 0.0086 16.8 2.4 0.4 11.5 0.0 3.9 3 0 0 3 3 3 1 Minor curli fiber component A RNA_pol_3_Rpc31 PF11705.8 ORX91195.1 - 0.011 16.0 4.7 0.029 14.6 4.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Gcn1_N PF12074.8 ORX91195.1 - 0.013 14.8 0.9 1.1 8.5 0.0 4.3 5 0 0 5 5 5 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Arm PF00514.23 ORX91195.1 - 0.016 15.2 11.2 0.63 10.2 0.1 7.6 9 0 0 9 9 7 0 Armadillo/beta-catenin-like repeat T3SS_needle_E PF08988.10 ORX91195.1 - 0.057 13.6 2.4 3.6 7.8 0.6 3.2 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DNA_alkylation PF08713.11 ORX91195.1 - 0.098 12.4 0.1 9.7 5.8 0.1 2.7 2 0 0 2 2 2 0 DNA alkylation repair enzyme PRC2_HTH_1 PF18118.1 ORX91195.1 - 0.13 13.1 2.2 30 5.5 0.0 4.0 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Sec7_N PF12783.7 ORX91195.1 - 0.14 12.0 27.1 0.43 10.5 2.7 7.1 5 2 0 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Tti2 PF10521.9 ORX91195.1 - 0.54 9.8 14.4 2.6 7.5 0.3 5.7 6 3 1 7 7 7 0 Tti2 family Ipi1_N PF12333.8 ORX91195.1 - 0.58 10.8 6.6 1.1e+02 3.5 0.0 6.4 7 1 0 7 7 7 0 Rix1 complex component involved in 60S ribosome maturation DUF4042 PF13251.6 ORX91195.1 - 0.78 9.4 5.1 28 4.4 0.1 5.2 5 1 1 6 6 5 0 Domain of unknown function (DUF4042) RRN3 PF05327.11 ORX91195.1 - 1.3 7.4 11.2 0.29 9.6 6.1 2.5 3 1 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 API5 PF05918.11 ORX91195.1 - 4.2 6.1 12.5 1.5 7.6 2.4 3.4 3 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Chs7 PF12271.8 ORX91196.1 - 2.1e-108 362.0 18.9 2.4e-108 361.8 18.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Chs7 PF12271.8 ORX91197.1 - 5.6e-102 341.0 14.7 6.4e-102 340.8 14.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2070 PF09843.9 ORX91197.1 - 7.4 4.7 18.2 11 4.1 18.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ISN1 PF06437.11 ORX91198.1 - 1.2e-142 475.7 0.0 1.4e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase IQ PF00612.27 ORX91199.1 - 0.0034 17.0 0.1 0.0034 17.0 0.1 2.3 3 0 0 3 3 3 1 IQ calmodulin-binding motif PAS_3 PF08447.12 ORX91201.1 - 1.9e-32 111.4 2.1 8.8e-17 61.2 0.4 3.2 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 ORX91201.1 - 1.1e-30 106.4 0.1 2.8e-30 105.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_16 PF13191.6 ORX91201.1 - 8.5e-23 81.6 0.0 3.4e-22 79.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Response_reg PF00072.24 ORX91201.1 - 1.6e-21 76.6 0.1 2.5e-19 69.5 0.1 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORX91201.1 - 3.3e-17 62.3 0.2 4.4e-16 58.7 0.0 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ORX91201.1 - 3.9e-16 59.2 0.0 1.4e-06 28.5 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORX91201.1 - 3.4e-14 52.8 0.0 4e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORX91201.1 - 2.2e-12 47.2 0.0 1.3e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold NACHT PF05729.12 ORX91201.1 - 3.5e-07 30.3 0.1 1.6e-06 28.1 0.0 2.3 2 1 0 2 2 1 1 NACHT domain GAF_2 PF13185.6 ORX91201.1 - 8.1e-05 22.9 0.0 0.00023 21.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_11 PF14598.6 ORX91201.1 - 0.00015 21.9 0.1 0.0064 16.6 0.0 2.9 2 0 0 2 2 2 1 PAS domain DnaB_C PF03796.15 ORX91201.1 - 0.0085 15.4 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 ORX91201.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 ORX91201.1 - 0.023 15.0 0.0 0.086 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORX91201.1 - 0.023 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 ORX91201.1 - 0.031 14.7 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORX91201.1 - 0.066 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain SNAP PF14938.6 ORX91201.1 - 0.14 11.5 4.7 1.7 8.0 0.2 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP HATPase_c_3 PF13589.6 ORX91201.1 - 0.18 11.7 0.0 0.56 10.0 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATPase PF06745.13 ORX91201.1 - 0.21 10.9 0.0 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 KaiC TPR_1 PF00515.28 ORX91201.1 - 0.3 11.0 4.9 4 7.4 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX91201.1 - 5.1 7.5 12.9 4.6 7.6 1.6 4.5 4 1 0 4 4 3 0 Tetratricopeptide repeat KH_8 PF17903.1 ORX91202.1 - 6.5e-31 106.3 0.0 2.3e-30 104.5 0.0 2.0 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORX91202.1 - 9e-06 25.4 0.2 2.7e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 KH domain Pfg27 PF09216.10 ORX91202.1 - 0.0088 15.9 1.1 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 Pfg27 Sec1 PF00995.23 ORX91203.1 - 6.3e-98 329.5 0.1 8.1e-98 329.1 0.1 1.1 1 0 0 1 1 1 1 Sec1 family PTR2 PF00854.21 ORX91204.1 - 1.5e-79 267.6 7.2 1.5e-79 267.6 7.2 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX91204.1 - 1.2e-13 50.7 29.2 5.6e-08 32.1 9.7 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 ORX91205.1 - 1.8e-16 60.4 0.1 2.1e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX91205.1 - 8.8e-12 45.3 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX91205.1 - 6.3e-09 35.8 0.0 7.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX91205.1 - 0.00081 19.6 0.1 0.0016 18.6 0.1 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX91205.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORX91205.1 - 0.0072 17.0 0.0 0.0082 16.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX91205.1 - 0.035 14.2 0.0 0.56 10.3 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PTR2 PF00854.21 ORX91206.1 - 1.5e-79 267.6 7.8 1.5e-79 267.6 7.8 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX91206.1 - 1.1e-14 54.2 26.3 2e-08 33.6 8.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Asp PF00026.23 ORX91207.1 - 2e-49 168.7 4.8 4e-49 167.8 4.8 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX91207.1 - 1.4e-08 35.2 8.0 0.0019 18.5 8.0 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX91207.1 - 0.015 15.1 0.1 0.32 10.7 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal PTR2 PF00854.21 ORX91208.1 - 1.5e-79 267.6 7.8 1.5e-79 267.6 7.8 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX91208.1 - 1.1e-14 54.2 26.3 2e-08 33.6 8.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Asp PF00026.23 ORX91209.1 - 2.1e-30 106.2 1.9 4.5e-23 82.2 1.1 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease PTR2 PF00854.21 ORX91210.1 - 9.9e-80 268.3 7.1 9.9e-80 268.3 7.1 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX91210.1 - 1.9e-14 53.4 26.9 2e-08 33.6 8.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily CBAH PF02275.18 ORX91211.1 - 0.018 14.7 0.3 0.024 14.3 0.3 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family COG5 PF10392.9 ORX91212.1 - 0.032 14.4 0.5 0.14 12.4 0.3 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 V-ATPase_G PF03179.15 ORX91212.1 - 0.18 12.4 3.0 0.16 12.5 0.5 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4349 PF14257.6 ORX91212.1 - 0.31 10.5 5.9 3.4 7.0 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Helicase_C PF00271.31 ORX91213.1 - 1.6e-06 28.4 0.0 1.9e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Strep_his_triad PF04270.13 ORX91216.1 - 0.079 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Streptococcal histidine triad protein Ysc84 PF04366.12 ORX91218.1 - 2.9e-44 149.9 0.9 6.6e-44 148.7 0.9 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORX91218.1 - 9.2e-16 57.2 0.2 2.2e-15 56.0 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORX91218.1 - 4.6e-11 42.4 0.0 8.3e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX91218.1 - 3.4e-10 39.5 0.0 1.1e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 ORX91219.1 - 1.2e-50 168.4 24.9 1.1e-07 32.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91219.1 - 8.5e-13 48.4 2.0 0.0023 18.2 0.0 4.9 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91219.1 - 3e-06 27.3 0.2 1.3e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX91219.1 - 5.5e-06 25.6 0.2 0.043 12.8 0.0 3.8 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORX91219.1 - 2.9e-05 22.8 0.1 0.32 9.5 0.0 2.9 2 1 1 3 3 3 3 Cytochrome D1 heme domain DUF1513 PF07433.11 ORX91219.1 - 3.4e-05 23.1 0.0 0.038 13.1 0.0 2.8 2 2 1 3 3 3 2 Protein of unknown function (DUF1513) Nup160 PF11715.8 ORX91219.1 - 0.0067 15.1 8.0 0.035 12.8 0.2 4.5 4 2 1 6 6 6 1 Nucleoporin Nup120/160 PD40 PF07676.12 ORX91219.1 - 0.048 13.6 1.0 38 4.4 0.1 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat adh_short PF00106.25 ORX91220.1 - 4.1e-40 137.3 0.1 6.1e-40 136.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX91220.1 - 1.1e-19 71.0 0.0 1.6e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX91220.1 - 3.3e-06 27.1 0.0 5.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX91220.1 - 0.0023 17.1 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Choline_transpo PF04515.12 ORX91221.1 - 1.3e-78 264.5 28.8 1.3e-78 264.5 28.8 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 ORX91221.1 - 0.026 15.2 9.2 0.022 15.4 6.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RHH_3 PF12651.7 ORX91221.1 - 0.2 11.6 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain DcpS_C PF11969.8 ORX91222.1 - 7.2e-18 65.1 0.1 9e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORX91222.1 - 2.2e-11 44.4 0.2 2.9e-11 44.0 0.2 1.1 1 0 0 1 1 1 1 HIT domain PARP PF00644.20 ORX91222.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain PAP2_C PF14360.6 ORX91223.1 - 5.2e-15 55.7 13.0 5.2e-15 55.7 13.0 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORX91223.1 - 0.00019 21.2 6.0 0.00019 21.2 6.0 2.4 2 1 1 3 3 3 1 PAP2 superfamily WLM PF08325.10 ORX91224.1 - 2.9e-55 187.3 0.0 3.8e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 ORX91224.1 - 0.0022 18.0 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 ORX91224.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 SprT-like family PDEase_I PF00233.19 ORX91225.1 - 7.9e-56 189.4 1.0 1.6e-55 188.4 1.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 ORX91225.1 - 0.00018 21.6 0.0 0.0055 16.8 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HD PF01966.22 ORX91225.1 - 0.022 15.0 0.1 0.36 11.1 0.0 2.5 2 0 0 2 2 2 0 HD domain SAM_2 PF07647.17 ORX91227.1 - 7.3e-09 35.6 0.0 2.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORX91227.1 - 2e-06 28.1 0.1 6.1e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 ORX91227.1 - 0.15 12.3 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) FGase PF05013.12 ORX91229.1 - 1.3e-07 32.1 0.6 0.00025 21.3 0.0 2.9 2 1 1 3 3 3 2 N-formylglutamate amidohydrolase zf-primase PF09329.11 ORX91230.1 - 1.1e-12 47.5 0.3 1.9e-12 46.8 0.3 1.4 1 0 0 1 1 1 1 Primase zinc finger Arrestin_C PF02752.22 ORX91231.1 - 8.2e-18 65.1 1.3 1.7e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX91231.1 - 2.2e-15 57.0 0.2 4.7e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX91231.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like GPI-anchored PF10342.9 ORX91232.1 - 3.7e-08 34.0 0.7 5.6e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ABC2_membrane PF01061.24 ORX91233.1 - 4.6e-93 310.4 58.5 1.6e-52 178.0 17.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORX91233.1 - 5.6e-34 117.6 0.0 6.8e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORX91233.1 - 5e-29 100.0 2.7 1.7e-21 75.9 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX91233.1 - 2.2e-10 41.0 0.0 9.8e-10 38.9 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORX91233.1 - 5.9e-10 38.8 54.2 5.1e-07 29.1 16.4 3.9 3 1 1 4 4 4 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX91233.1 - 3.2e-06 27.1 0.1 0.0018 18.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORX91233.1 - 4.1e-06 27.3 0.0 0.0092 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORX91233.1 - 4.5e-06 26.7 0.0 0.038 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORX91233.1 - 2.2e-05 24.7 0.4 1.4 9.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 ORX91233.1 - 3.7e-05 23.4 0.3 0.022 14.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORX91233.1 - 0.001 18.7 0.1 0.01 15.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX91233.1 - 0.0016 18.7 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORX91233.1 - 0.0046 16.6 0.2 0.29 10.7 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORX91233.1 - 0.013 15.3 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX91233.1 - 0.013 15.6 0.1 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 ORX91233.1 - 0.026 15.1 0.0 3.5 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORX91233.1 - 0.033 14.6 0.0 8.9 6.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ORX91233.1 - 0.035 14.0 0.2 1 9.2 0.1 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 ORX91233.1 - 0.036 13.5 0.1 2.5 7.5 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ORX91233.1 - 0.047 13.9 0.7 1 9.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORX91233.1 - 0.048 13.8 0.1 1.2 9.2 0.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 ORX91233.1 - 0.083 12.8 1.9 3.4 7.5 0.3 2.7 3 0 0 3 3 2 0 NACHT domain MeaB PF03308.16 ORX91233.1 - 0.087 11.8 0.1 6.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 ORX91233.1 - 0.11 12.2 0.9 4.9 6.9 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 ORX91233.1 - 0.12 12.3 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_13 PF13166.6 ORX91233.1 - 0.15 10.7 0.4 1.5 7.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 ORX91233.1 - 0.18 12.3 0.1 0.55 10.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 ORX91234.1 - 2e-16 59.9 24.3 2.7e-16 59.4 24.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX91234.1 - 3.2e-14 52.9 8.3 3.2e-14 52.9 8.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX91234.1 - 3.2e-05 23.0 0.0 0.059 12.2 6.3 2.1 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORX91234.1 - 0.0086 15.1 6.4 0.021 13.8 6.4 1.7 1 0 0 1 1 1 1 PUCC protein Sec2p PF06428.11 ORX91235.1 - 7.1e-16 58.0 17.5 7.1e-16 58.0 17.5 3.2 1 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p HscB_4_cys PF18256.1 ORX91235.1 - 0.72 9.7 4.3 0.27 11.1 0.5 2.1 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Polysacc_deac_1 PF01522.21 ORX91236.1 - 6.8e-26 90.6 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX91236.1 - 9e-15 54.9 50.4 3.1e-07 30.8 21.7 2.6 2 0 0 2 2 2 2 Chitin recognition protein GST_N PF02798.20 ORX91237.1 - 7e-17 61.6 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX91237.1 - 3.9e-14 52.6 0.0 1e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX91237.1 - 5.9e-13 49.0 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX91237.1 - 5.4e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORX91237.1 - 1.9e-09 37.6 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX91237.1 - 1.5e-06 28.1 0.0 3.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORX91237.1 - 0.015 15.0 0.0 0.063 13.1 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NPA PF16469.5 ORX91240.1 - 0.005 17.4 1.3 0.01 16.4 1.3 1.5 1 0 0 1 1 1 1 Nematode polyprotein allergen ABA-1 Beta-Casp PF10996.8 ORX91240.1 - 0.11 12.8 0.1 0.25 11.7 0.0 1.6 1 1 0 1 1 1 0 Beta-Casp domain RNA_pol_Rpb1_5 PF04998.17 ORX91242.1 - 1.1e-19 71.0 0.0 1.9e-19 70.2 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Sel1 PF08238.12 ORX91245.1 - 2.1e-29 101.3 22.7 3.2e-09 37.1 0.3 7.9 7 0 0 7 7 7 6 Sel1 repeat ANAPC3 PF12895.7 ORX91245.1 - 0.45 10.8 2.1 8.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORX91245.1 - 6.4 7.6 9.2 99 3.9 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Cupin_2 PF07883.11 ORX91246.1 - 1.6e-15 56.5 0.4 3e-15 55.7 0.3 1.5 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 ORX91246.1 - 0.0015 18.3 0.8 0.019 14.7 0.2 2.0 1 1 1 2 2 2 1 Auxin binding protein Cupin_3 PF05899.12 ORX91246.1 - 0.0024 17.5 0.1 0.0068 16.1 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 ORX91246.1 - 0.0093 15.9 0.0 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Svf1_C PF17187.4 ORX91247.1 - 8.1e-36 123.3 0.0 1.3e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORX91247.1 - 8.3e-20 71.5 0.1 1.2e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain CO_deh_flav_C PF03450.17 ORX91248.1 - 0.05 13.8 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain CD24 PF14984.6 ORX91248.1 - 0.11 12.7 0.1 3.8 7.8 0.0 3.1 4 0 0 4 4 4 0 CD24 protein zf-C2H2 PF00096.26 ORX91249.1 - 3e-09 36.8 8.7 1.5e-05 25.2 2.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX91249.1 - 5.9e-08 32.8 11.1 2.3e-07 30.9 0.9 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX91249.1 - 1.1e-06 29.0 7.2 0.0092 16.7 1.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORX91249.1 - 0.00041 20.9 0.7 0.15 12.7 0.0 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX91249.1 - 0.012 15.9 0.7 0.063 13.6 0.7 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORX91249.1 - 0.028 14.6 1.1 0.035 14.3 1.1 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger OrsD PF12013.8 ORX91249.1 - 0.12 12.8 2.9 5.1 7.6 0.1 2.1 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D ThrE PF06738.12 ORX91251.1 - 1.1e-62 211.5 19.2 3.1e-54 183.9 0.9 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORX91251.1 - 1.8e-11 44.3 27.8 1.6e-08 34.8 12.8 2.2 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF373 PF04123.13 ORX91251.1 - 0.0048 16.4 7.0 0.43 10.0 6.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF373) DUF1764 PF08576.10 ORX91251.1 - 0.53 11.2 2.0 1.2 10.1 1.9 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) ThrE PF06738.12 ORX91252.1 - 2.6e-58 197.2 14.7 2.4e-53 181.0 3.4 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORX91252.1 - 8.3e-13 48.6 20.4 7.9e-10 39.0 4.6 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Tmemb_18A PF09771.9 ORX91252.1 - 0.034 14.6 0.2 0.35 11.3 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 188 Flavokinase PF01687.17 ORX91252.1 - 0.05 13.9 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Riboflavin kinase Keratin_assoc PF09775.9 ORX91252.1 - 0.11 12.1 5.0 0.15 11.7 3.4 2.1 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Acetyltransf_1 PF00583.25 ORX91253.1 - 1.9e-17 63.5 0.0 3.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX91253.1 - 1.9e-13 50.5 0.0 2.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX91253.1 - 5.7e-11 42.7 0.0 9.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX91253.1 - 5.8e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 ORX91253.1 - 2.1e-05 24.6 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORX91253.1 - 4.4e-05 24.2 0.1 0.00014 22.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX91253.1 - 0.00021 21.2 0.1 0.00067 19.6 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 ORX91253.1 - 0.0016 18.6 0.0 0.0033 17.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ORX91253.1 - 0.0088 16.2 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ORX91253.1 - 0.023 14.5 0.1 0.084 12.7 0.0 1.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORX91253.1 - 0.041 13.9 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DNA_pol_B PF00136.21 ORX91256.1 - 6.3e-14 51.5 0.4 6.4e-14 51.5 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase family B PhyH PF05721.13 ORX91258.1 - 1.7e-26 93.8 0.0 2.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORX91258.1 - 0.041 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PAP2 PF01569.21 ORX91259.1 - 4.5e-27 94.5 0.9 4.5e-27 94.5 0.9 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX91259.1 - 0.0055 16.4 9.7 0.072 12.8 6.0 2.8 1 1 1 2 2 2 1 PAP2 superfamily DUF3094 PF11293.8 ORX91259.1 - 0.18 11.6 1.6 0.38 10.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DotU PF09850.9 ORX91259.1 - 0.48 10.1 1.5 12 5.5 0.0 2.8 3 0 0 3 3 3 0 Type VI secretion system protein DotU Peptidase_U4 PF03419.13 ORX91259.1 - 1.7 7.9 11.0 0.8 8.9 0.1 3.0 1 1 1 2 2 2 0 Sporulation factor SpoIIGA PAP2_C PF14360.6 ORX91259.1 - 1.8 9.2 10.9 0.19 12.3 1.2 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Polysacc_synt_C PF14667.6 ORX91259.1 - 2.4 8.2 10.1 1 9.4 3.2 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain PAP2 PF01569.21 ORX91260.1 - 1.4e-27 96.1 0.9 1.4e-27 96.1 0.9 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX91260.1 - 0.011 15.5 6.1 0.045 13.4 6.1 2.0 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.6 ORX91260.1 - 0.099 13.2 7.4 0.097 13.2 1.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Peptidase_U4 PF03419.13 ORX91260.1 - 0.94 8.7 9.6 0.45 9.8 0.2 2.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Polysacc_synt_C PF14667.6 ORX91260.1 - 1.1 9.3 7.9 0.79 9.8 3.2 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PhyH PF05721.13 ORX91261.1 - 1.7e-26 93.8 0.0 2.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORX91261.1 - 0.04 14.3 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase HD PF01966.22 ORX91262.1 - 4e-07 30.3 0.0 6.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 ORX91262.1 - 0.00068 19.4 1.3 0.0013 18.5 1.3 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 ORX91262.1 - 0.0038 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 HDOD domain MIOX PF05153.15 ORX91262.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Myo-inositol oxygenase Peptidase_M16_M PF16187.5 ORX91263.1 - 4.7e-66 222.9 2.0 3.8e-36 124.8 0.1 2.2 1 1 1 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORX91263.1 - 1.1e-43 148.8 0.2 2.4e-43 147.7 0.1 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORX91263.1 - 1.2e-23 84.1 0.0 2.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain TRAM_LAG1_CLN8 PF03798.16 ORX91264.1 - 1.9e-07 31.0 1.7 2.6e-07 30.6 1.7 1.2 1 0 0 1 1 1 1 TLC domain Defensin_propep PF00879.18 ORX91265.1 - 0.02 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Defensin propeptide DUF1180 PF06679.12 ORX91265.1 - 0.028 14.9 0.3 0.03 14.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Conotoxin PF02950.17 ORX91265.1 - 0.13 13.3 0.1 0.21 12.6 0.1 1.5 1 1 0 1 1 1 0 Conotoxin DJ-1_PfpI PF01965.24 ORX91267.1 - 2.8e-47 160.6 0.4 3.2e-47 160.4 0.4 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX91267.1 - 3.6e-07 30.1 0.0 5.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 ORX91267.1 - 0.00015 21.5 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 ORX91267.1 - 0.0017 18.0 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 ORX91267.1 - 0.0057 16.5 0.1 0.023 14.6 0.0 1.8 1 1 1 2 2 2 1 SNO glutamine amidotransferase family VWA PF00092.28 ORX91267.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Pkinase PF00069.25 ORX91268.1 - 3.7e-74 249.4 0.0 4.7e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91268.1 - 2.5e-48 164.6 0.0 3.8e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX91268.1 - 1.4e-06 27.8 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX91268.1 - 2.3e-05 23.4 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PBD PF00786.28 ORX91268.1 - 3.5e-05 24.1 0.0 9.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain APH PF01636.23 ORX91268.1 - 0.0049 16.8 0.0 0.24 11.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORX91268.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX91268.1 - 0.12 11.3 0.4 0.21 10.5 0.4 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Histone PF00125.24 ORX91269.1 - 3.3e-45 153.7 0.7 4.8e-45 153.1 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX91269.1 - 7.2e-06 26.3 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX91269.1 - 1.9e-05 24.7 0.1 2.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORX91269.1 - 0.0028 18.3 1.9 0.0036 17.9 1.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORX91269.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP-synt_J PF04911.12 ORX91270.1 - 1e-23 82.6 0.6 1.2e-23 82.4 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain CDP-OH_P_transf PF01066.21 ORX91271.1 - 1.2e-17 64.4 0.1 1.2e-17 64.4 0.1 3.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase EBP PF05241.12 ORX91271.1 - 2.3 7.6 21.7 0.05 13.1 1.3 3.3 2 1 1 3 3 3 0 Emopamil binding protein Arrestin_N PF00339.29 ORX91272.1 - 3.3e-11 43.4 0.0 7.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX91272.1 - 2.4e-06 28.1 0.1 4.4e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX91272.1 - 0.016 14.9 0.0 0.17 11.5 0.0 2.2 1 1 1 2 2 2 0 Arrestin_N terminal like Thi4 PF01946.17 ORX91274.1 - 1.9e-106 354.6 1.4 2.3e-106 354.3 1.4 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORX91274.1 - 1e-14 54.9 2.0 3.2e-09 36.9 0.4 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORX91274.1 - 3.8e-09 36.1 1.9 6.7e-06 25.4 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORX91274.1 - 1.2e-08 35.0 0.1 3e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX91274.1 - 3e-06 26.7 0.2 5.2e-06 25.9 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX91274.1 - 6.5e-06 25.1 0.6 7e-05 21.7 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ORX91274.1 - 3.7e-05 23.0 0.9 8e-05 21.9 0.4 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORX91274.1 - 7.7e-05 22.7 0.1 0.00025 21.1 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORX91274.1 - 0.00011 21.5 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX91274.1 - 0.00031 20.2 0.2 0.00031 20.2 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORX91274.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORX91274.1 - 0.0058 17.2 0.2 0.0058 17.2 0.2 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX91274.1 - 0.0098 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 ORX91274.1 - 0.016 14.6 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 ORX91274.1 - 0.056 12.3 0.2 0.24 10.2 0.1 1.8 1 1 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 ORX91274.1 - 0.15 11.1 0.8 0.33 10.0 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.32 ORX91275.1 - 1.2e-15 57.5 4.6 0.03 15.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat F-box-like PF12937.7 ORX91275.1 - 3.1e-10 39.8 0.0 7.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX91275.1 - 2.7e-07 30.8 0.0 0.00024 21.3 0.0 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX91275.1 - 3e-06 27.0 0.0 6.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 ORX91275.1 - 0.00097 18.9 16.7 0.27 11.2 0.1 4.1 4 0 0 4 4 4 3 Ubiquitin interaction motif His_Phos_1 PF00300.22 ORX91276.1 - 6.6e-26 91.2 0.0 8.3e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C2H2 PF00096.26 ORX91277.1 - 5.9e-11 42.2 13.7 2.9e-05 24.3 4.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX91277.1 - 1.6e-06 28.5 10.6 0.0022 18.7 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX91277.1 - 3.6e-06 27.1 13.3 1.3e-05 25.4 0.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORX91277.1 - 0.0011 18.6 6.4 0.0096 15.7 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORX91277.1 - 0.048 14.0 0.5 0.78 10.1 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX91277.1 - 0.057 14.1 0.4 0.81 10.4 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX91277.1 - 0.085 13.6 3.5 0.24 12.1 3.5 1.8 1 1 0 1 1 1 0 TRAF-type zinc finger MS_channel PF00924.18 ORX91278.1 - 3.8e-19 69.1 0.6 7e-19 68.2 0.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 ORX91278.1 - 2.6e-05 23.5 1.3 6.5e-05 22.2 1.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORX91278.1 - 0.0001 22.0 0.3 0.00029 20.5 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORX91278.1 - 0.0019 17.6 0.6 0.004 16.6 0.6 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORX91278.1 - 0.021 15.2 0.1 0.064 13.7 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair DUF4842 PF16130.5 ORX91278.1 - 0.13 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4842) CD45 PF12567.8 ORX91279.1 - 0.048 13.6 0.7 0.18 11.8 0.7 2.0 1 0 0 1 1 1 0 Leukocyte receptor CD45 TPR_1 PF00515.28 ORX91280.1 - 1.2e-13 50.3 0.0 3.9e-06 26.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX91280.1 - 1.4e-10 40.5 0.0 0.00013 21.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 ORX91280.1 - 6.5e-10 38.7 0.4 1.6e-09 37.4 0.4 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_8 PF13181.6 ORX91280.1 - 2e-08 33.8 0.1 6.9e-05 22.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.31 ORX91280.1 - 0.00044 20.3 0.1 0.0042 17.2 0.0 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.6 ORX91280.1 - 0.0012 19.1 0.1 2.8 8.3 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX91280.1 - 0.0012 19.5 0.0 8.6 7.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat CUE PF02845.16 ORX91280.1 - 0.014 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 CUE domain TPR_11 PF13414.6 ORX91280.1 - 0.017 14.8 0.1 1.1 9.0 0.1 2.7 2 0 0 2 2 2 0 TPR repeat UBA_4 PF14555.6 ORX91280.1 - 0.02 14.7 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain TPR_16 PF13432.6 ORX91280.1 - 0.07 13.8 0.1 22 5.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORX91280.1 - 0.083 13.1 0.1 15 5.8 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat GIT1_C PF12205.8 ORX91280.1 - 0.089 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term MRI PF15325.6 ORX91280.1 - 0.24 12.5 0.1 0.24 12.5 0.1 4.2 4 1 1 5 5 4 0 Modulator of retrovirus infection Hydantoinase_A PF01968.18 ORX91280.1 - 0.39 9.9 1.8 9.8 5.3 0.0 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase RFC1 PF08519.12 ORX91282.1 - 4.6e-58 195.8 0.0 1.1e-57 194.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 ORX91282.1 - 1.8e-15 57.1 0.0 4.8e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 ORX91282.1 - 1.2e-12 48.4 0.0 2.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORX91282.1 - 1.1e-08 35.3 0.3 2.8e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 ORX91282.1 - 1.2e-05 25.6 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX91282.1 - 0.00013 22.4 0.0 0.011 16.2 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORX91282.1 - 0.00022 21.2 0.0 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORX91282.1 - 0.00093 19.0 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORX91282.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORX91282.1 - 0.006 17.1 0.0 0.034 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.7 ORX91282.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_24 PF13479.6 ORX91282.1 - 0.015 15.1 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORX91282.1 - 0.017 15.1 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX91282.1 - 0.021 14.8 0.0 0.99 9.3 0.0 2.5 1 1 1 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 ORX91282.1 - 0.028 14.6 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_assoc_2 PF16193.5 ORX91282.1 - 0.031 14.6 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 ORX91282.1 - 0.033 14.3 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX91282.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PSP1 PF04468.12 ORX91283.1 - 9.7e-34 115.5 2.4 1.9e-33 114.6 2.4 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region SGL PF08450.12 ORX91284.1 - 1.2e-29 103.6 0.0 1.3e-27 97.0 0.0 2.2 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 ORX91284.1 - 0.031 13.5 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SBBP PF06739.11 ORX91284.1 - 0.08 13.0 2.8 5.6 7.0 0.1 3.4 2 1 0 2 2 2 0 Beta-propeller repeat Arylesterase PF01731.20 ORX91284.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 Arylesterase SGL PF08450.12 ORX91285.1 - 4.2e-29 101.8 0.6 8.6e-28 97.6 0.1 2.4 1 1 2 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORX91285.1 - 0.0092 16.2 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 Arylesterase Lactonase PF10282.9 ORX91285.1 - 0.018 14.3 0.0 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SdiA-regulated PF06977.11 ORX91285.1 - 0.066 12.4 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated SBBP PF06739.11 ORX91285.1 - 0.085 12.9 0.5 17 5.5 0.1 3.1 2 0 0 2 2 2 0 Beta-propeller repeat Phytase-like PF13449.6 ORX91285.1 - 0.11 12.5 0.0 0.51 10.2 0.0 2.0 1 1 0 1 1 1 0 Esterase-like activity of phytase NHL PF01436.21 ORX91285.1 - 0.19 11.8 1.9 15 5.8 0.1 4.3 5 0 0 5 5 5 0 NHL repeat SBP_bac_11 PF13531.6 ORX91286.1 - 3.8e-05 23.6 0.1 0.00022 21.1 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ORX91286.1 - 0.0013 18.6 7.0 0.0062 16.4 7.0 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein ARID PF01388.21 ORX91286.1 - 0.01 16.5 0.0 0.12 13.1 0.0 2.4 2 1 0 2 2 2 0 ARID/BRIGHT DNA binding domain SBP_bac_1 PF01547.25 ORX91286.1 - 0.024 14.6 2.5 1.1 9.2 2.5 2.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ORX91286.1 - 0.027 13.9 0.1 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein SMN PF06003.12 ORX91290.1 - 2.7e-10 39.9 7.6 4.6e-10 39.2 7.5 1.4 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 ORX91290.1 - 0.00041 20.4 0.1 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Tudor domain DUF4537 PF15057.6 ORX91290.1 - 0.0027 17.7 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 ORX91290.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain 53-BP1_Tudor PF09038.10 ORX91290.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor UNC-93 PF05978.16 ORX91291.1 - 2.6e-10 40.2 9.9 2.6e-10 40.2 9.9 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX91291.1 - 2.6e-09 36.5 33.1 2.6e-09 36.5 33.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SYS1 PF09801.9 ORX91292.1 - 2.4e-46 157.5 8.4 2.7e-46 157.3 8.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF1713 PF08213.11 ORX91293.1 - 2.1e-14 53.1 18.0 3.3e-14 52.5 18.0 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Kin17_mid PF10357.9 ORX91293.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Promethin PF16015.5 ORX91294.1 - 4.2e-10 39.5 0.5 6.3e-10 38.9 0.5 1.2 1 0 0 1 1 1 1 Promethin YtxH PF12732.7 ORX91294.1 - 0.0011 19.5 0.7 0.14 12.7 0.2 2.6 2 0 0 2 2 2 1 YtxH-like protein DUF2207 PF09972.9 ORX91294.1 - 0.041 12.7 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Oleosin PF01277.17 ORX91294.1 - 0.56 10.0 12.2 1.1 9.1 7.2 3.0 2 1 0 2 2 2 0 Oleosin DUF883 PF05957.13 ORX91294.1 - 0.61 10.7 0.1 0.61 10.7 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 ORX91294.1 - 2.6 8.2 6.1 1.2 9.3 0.6 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein WD40 PF00400.32 ORX91295.1 - 4.5e-20 71.6 15.0 0.00042 21.1 0.2 9.2 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91295.1 - 6.1e-11 42.5 0.0 3.6e-08 33.6 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX91295.1 - 0.0019 17.3 0.3 1.1 8.1 0.0 3.8 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORX91295.1 - 0.14 11.5 0.9 3.9 6.7 0.2 2.7 3 0 0 3 3 3 0 WD40-like domain Uds1 PF15456.6 ORX91295.1 - 0.69 10.1 4.1 2.2 8.5 4.1 1.8 1 0 0 1 1 1 0 Up-regulated During Septation STE PF02200.16 ORX91296.1 - 3.6e-51 172.2 0.3 4.5e-51 171.9 0.3 1.1 1 0 0 1 1 1 1 STE like transcription factor PIH1 PF08190.12 ORX91297.1 - 2.9e-24 85.4 0.0 4.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 ORX91297.1 - 6.9e-11 42.4 0.0 2.2e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 PIH1 CS-like domain CAF1C_H4-bd PF12265.8 ORX91298.1 - 1e-19 70.6 2.9 5.5e-19 68.2 0.1 2.8 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORX91298.1 - 1.8e-17 63.4 12.5 2.4e-07 31.4 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91298.1 - 3.1e-07 30.6 2.4 0.0013 19.0 0.4 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91298.1 - 2e-05 24.6 1.0 9.4e-05 22.4 1.0 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CDC27 PF09507.10 ORX91299.1 - 0.009 15.5 2.1 0.011 15.1 2.1 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 ORX91299.1 - 0.12 11.9 11.4 0.16 11.6 11.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.11 ORX91299.1 - 0.69 8.7 2.9 0.87 8.4 2.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Macoilin PF09726.9 ORX91299.1 - 3 6.3 5.9 3.3 6.2 5.9 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_transf_34 PF05637.12 ORX91300.1 - 3e-20 73.0 0.3 3.8e-19 69.4 0.3 2.2 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family SSB PF00436.25 ORX91300.1 - 2.5e-15 56.4 0.1 6.2e-15 55.1 0.1 1.7 2 0 0 2 2 2 1 Single-strand binding protein family DUF273 PF03314.14 ORX91300.1 - 2.8e-07 30.3 0.2 6e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Acetyltransf_1 PF00583.25 ORX91302.1 - 3.8e-11 43.3 0.1 4.8e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX91302.1 - 4.2e-08 33.5 0.5 6.2e-08 33.0 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX91302.1 - 1.8e-07 31.2 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX91302.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 ORX91302.1 - 0.049 13.8 0.1 0.12 12.5 0.0 1.6 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Nucleocap_ssRNA PF11128.8 ORX91302.1 - 0.075 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid DUF1053 PF06327.14 ORX91303.1 - 0.00027 21.4 7.6 9.1 6.9 0.4 6.2 1 1 8 9 9 9 2 Domain of Unknown Function (DUF1053) DUF4054 PF13262.6 ORX91303.1 - 5.5 7.1 56.5 16 5.5 0.1 11.8 2 2 11 13 13 13 0 Protein of unknown function (DUF4054) AIM24 PF01987.17 ORX91304.1 - 3e-50 170.8 0.0 3.4e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Scm3 PF10384.9 ORX91304.1 - 0.038 13.7 0.1 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 Glyco_hydro_32N PF00251.20 ORX91305.1 - 6.9e-64 216.3 2.1 1.3e-63 215.4 2.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORX91305.1 - 3.9e-32 111.4 0.2 6e-32 110.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 ORX91305.1 - 0.0044 17.1 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 ORX91305.1 - 0.068 13.2 0.2 0.68 10.2 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat ADP_ribosyl_GH PF03747.14 ORX91306.1 - 1.6e-48 165.9 0.0 8.3e-35 120.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylglycohydrolase p450 PF00067.22 ORX91308.1 - 6.5e-67 226.3 0.1 3.6e-66 223.8 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 DHC_N1 PF08385.12 ORX91308.1 - 0.0094 14.6 0.3 0.013 14.1 0.3 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 NmrA PF05368.13 ORX91309.1 - 0.011 15.3 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family NmrA PF05368.13 ORX91310.1 - 6.3e-30 104.5 0.1 8.6e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX91310.1 - 2.8e-19 69.7 0.0 4.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX91310.1 - 9.5e-10 38.3 0.0 5.6e-07 29.3 0.1 3.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX91310.1 - 3.3e-06 26.3 0.0 6.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORX91310.1 - 1.2e-05 25.6 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 ORX91310.1 - 0.00027 20.9 0.1 0.00066 19.6 0.0 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 ORX91310.1 - 0.00055 20.0 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ORX91310.1 - 0.00056 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORX91310.1 - 0.0021 17.5 0.0 0.041 13.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 ORX91310.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 ORX91310.1 - 0.016 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 ORX91310.1 - 0.019 14.1 0.2 0.99 8.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DUF5022 PF16425.5 ORX91310.1 - 0.057 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) Polysacc_synt_2 PF02719.15 ORX91310.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 ORX91310.1 - 0.15 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 ORX91311.1 - 3.3e-29 102.1 0.1 4.3e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX91311.1 - 3.2e-17 63.0 0.0 6.9e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX91311.1 - 1.2e-09 38.0 0.0 6.2e-06 25.8 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX91311.1 - 3.4e-05 23.0 0.0 6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORX91311.1 - 0.00097 18.6 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 ORX91311.1 - 0.0039 17.1 0.1 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 KR domain Tau95 PF09734.9 ORX91311.1 - 0.014 16.2 0.0 0.033 15.0 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Shikimate_DH PF01488.20 ORX91311.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_binding_2 PF13380.6 ORX91311.1 - 0.041 14.4 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain TrkA_N PF02254.18 ORX91311.1 - 0.044 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 ORX91311.1 - 0.058 12.5 0.5 0.98 8.5 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 ORX91311.1 - 0.086 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 ORX91312.1 - 6.3e-30 104.5 0.1 8.6e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX91312.1 - 2.8e-19 69.7 0.0 4.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX91312.1 - 9.5e-10 38.3 0.0 5.6e-07 29.3 0.1 3.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX91312.1 - 3.3e-06 26.3 0.0 6.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORX91312.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 ORX91312.1 - 0.00027 20.9 0.1 0.00066 19.6 0.0 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 ORX91312.1 - 0.00055 20.0 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ORX91312.1 - 0.00057 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORX91312.1 - 0.0021 17.5 0.0 0.041 13.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 ORX91312.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 ORX91312.1 - 0.017 15.3 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 ORX91312.1 - 0.018 14.1 0.1 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DUF5022 PF16425.5 ORX91312.1 - 0.058 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) Polysacc_synt_2 PF02719.15 ORX91312.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 ORX91312.1 - 0.15 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DHO_dh PF01180.21 ORX91313.1 - 2.2e-97 325.9 0.0 2.7e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 ORX91313.1 - 0.00019 20.6 0.0 0.0032 16.5 0.1 2.4 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 ORX91313.1 - 0.0057 16.1 0.1 0.0088 15.5 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase MamL-1 PF09596.10 ORX91313.1 - 0.05 13.9 0.2 0.082 13.2 0.2 1.3 1 0 0 1 1 1 0 MamL-1 domain IMPDH PF00478.25 ORX91313.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain PAXIP1_C PF15364.6 ORX91314.1 - 0.0082 16.5 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein OSTbeta PF15048.6 ORX91314.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein UQ_con PF00179.26 ORX91315.1 - 4.4e-48 162.5 0.0 5.6e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORX91315.1 - 0.0081 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 ORX91315.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 ORX91315.1 - 0.083 13.2 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain PT PF04886.12 ORX91316.1 - 0.031 13.8 34.9 0.078 12.5 11.5 3.7 1 1 1 2 2 2 0 PT repeat PIF1 PF05970.14 ORX91317.1 - 4.9e-11 42.4 0.1 8.6e-11 41.6 0.1 1.3 1 1 0 1 1 1 1 PIF1-like helicase Es2 PF09751.9 ORX91318.1 - 0.25 11.0 4.2 0.3 10.8 4.2 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 DIM PF08194.12 ORX91318.1 - 0.36 11.1 0.3 0.36 11.1 0.3 2.4 3 0 0 3 3 3 0 DIM protein ORC6 PF05460.13 ORX91318.1 - 0.62 9.3 6.6 0.71 9.1 6.6 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1180 PF06679.12 ORX91318.1 - 1.9 8.9 7.5 2.3 8.6 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 ORX91318.1 - 7 5.1 7.2 7.5 5.0 7.2 1.0 1 0 0 1 1 1 0 Macoilin family LRR_2 PF07723.13 ORX91319.1 - 5 7.9 9.1 7.1 7.5 0.3 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat Inhibitor_I9 PF05922.16 ORX91320.1 - 0.00016 22.2 0.9 0.00021 21.9 0.3 1.5 2 0 0 2 2 2 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX91320.1 - 0.073 13.1 0.2 0.094 12.8 0.2 1.2 1 0 0 1 1 1 0 DivIVA protein DUF1414 PF07208.11 ORX91320.1 - 0.097 12.7 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Peptidase_S8 PF00082.22 ORX91321.1 - 3.2e-35 121.8 18.4 6.6e-35 120.8 18.4 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX91321.1 - 7.4e-08 33.0 0.2 1.4e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX91321.1 - 0.018 15.1 0.4 0.032 14.3 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX91322.1 - 2.3e-14 53.3 1.4 2.9e-14 53.0 1.4 1.1 1 0 0 1 1 1 1 Subtilase family Polysacc_deac_1 PF01522.21 ORX91323.1 - 2.7e-28 98.3 0.0 4.8e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX91323.1 - 2.7e-08 34.2 23.3 5.6e-08 33.1 23.3 1.6 1 0 0 1 1 1 1 Chitin recognition protein Mucin PF01456.17 ORX91323.1 - 0.0028 17.6 8.0 0.0056 16.7 8.0 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF2334 PF10096.9 ORX91323.1 - 0.047 13.3 0.0 0.08 12.6 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 ORX91324.1 - 8.2e-27 93.6 0.0 1.3e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX91324.1 - 1.4e-07 31.8 21.4 1.4e-07 31.8 21.4 2.0 2 0 0 2 2 2 1 Chitin recognition protein DUF5011 PF16403.5 ORX91324.1 - 0.079 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) PAF-AH_p_II PF03403.13 ORX91325.1 - 1.4e-19 69.9 0.0 3e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 ORX91325.1 - 2.8e-05 23.9 0.0 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX91325.1 - 0.00013 21.4 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORX91325.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 ORX91325.1 - 0.0016 18.2 0.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 ORX91325.1 - 0.0027 18.3 0.1 0.0043 17.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX91325.1 - 0.075 12.7 0.4 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 ORX91325.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CBM_5_12_2 PF14600.6 ORX91326.1 - 0.0091 15.9 1.1 0.016 15.1 1.0 1.5 1 1 0 1 1 1 1 Cellulose-binding domain CBM_5_12 PF02839.14 ORX91326.1 - 0.027 15.0 4.6 0.027 15.0 4.6 2.6 3 1 0 3 3 3 0 Carbohydrate binding domain Glyco_hydro_18 PF00704.28 ORX91327.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX91327.1 - 0.015 15.9 4.5 0.015 15.9 4.5 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain DUF1962 PF09227.10 ORX91328.1 - 0.019 15.3 2.4 0.019 15.3 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) Sporozoite_P67 PF05642.11 ORX91328.1 - 0.28 9.2 9.9 0.33 9.0 9.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 ORX91329.1 - 2.2e-11 43.7 0.0 4e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91329.1 - 8.9e-08 31.7 0.0 7.6e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX91329.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Myticin-prepro PF10690.9 ORX91330.1 - 0.15 12.3 0.3 0.15 12.3 0.3 2.0 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel ACC_central PF08326.12 ORX91331.1 - 3.7e-240 799.1 0.0 4.5e-240 798.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORX91331.1 - 1.8e-172 574.4 0.0 2.4e-172 574.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORX91331.1 - 5.3e-52 176.4 0.0 1.4e-51 175.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORX91331.1 - 9.8e-29 100.1 0.0 2.1e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORX91331.1 - 4.5e-21 75.0 0.0 3e-20 72.3 0.0 2.4 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORX91331.1 - 6.7e-16 57.9 0.0 3.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 ORX91331.1 - 0.00055 20.0 0.0 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORX91331.1 - 0.013 15.1 0.0 0.044 13.3 0.0 1.9 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ORX91331.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MbeD_MobD PF04899.12 ORX91331.1 - 0.19 11.8 1.1 0.87 9.7 1.1 2.1 1 0 0 1 1 1 0 MbeD/MobD like SWIRM PF04433.17 ORX91332.1 - 9.8e-13 48.3 0.0 2e-12 47.3 0.0 1.4 2 0 0 2 2 2 1 SWIRM domain Hexokinase_2 PF03727.16 ORX91333.1 - 4e-70 236.0 0.0 5.1e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX91333.1 - 4.5e-62 209.5 0.0 6.4e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NADH_4Fe-4S PF10589.9 ORX91333.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region BTG PF07742.12 ORX91334.1 - 4.8e-29 100.6 0.0 5.6e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 BTG family DED PF01335.21 ORX91334.1 - 0.13 12.6 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Death effector domain RGS PF00615.19 ORX91335.1 - 2.8e-17 63.1 2.4 4.5e-17 62.4 2.4 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX91335.1 - 2e-08 34.3 16.3 8.9e-08 32.1 16.3 1.9 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR COMPASS-Shg1 PF05205.12 ORX91335.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 bZIP_1 PF00170.21 ORX91335.1 - 9.4 6.4 7.1 0.61 10.2 0.7 2.3 3 0 0 3 3 3 0 bZIP transcription factor Protoglobin PF11563.8 ORX91341.1 - 1.2e-37 129.3 0.5 1.4e-37 129.0 0.5 1.0 1 0 0 1 1 1 1 Protoglobin tRNA-synt_1e PF01406.19 ORX91341.1 - 0.12 11.7 0.7 0.14 11.5 0.7 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PX PF00787.24 ORX91341.1 - 0.13 12.3 0.2 0.56 10.2 0.0 2.1 3 0 0 3 3 3 0 PX domain Nucleos_tra2_C PF07662.13 ORX91342.1 - 8.1e-75 251.2 7.1 8.1e-75 251.2 7.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX91342.1 - 9.2e-24 83.8 3.4 9.2e-24 83.8 3.4 4.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX91342.1 - 0.0046 17.2 8.6 0.0046 17.2 8.6 4.3 3 2 0 3 3 3 1 Nucleoside recognition Protoglobin PF11563.8 ORX91343.1 - 1.6e-37 128.8 0.6 2e-37 128.5 0.6 1.1 1 0 0 1 1 1 1 Protoglobin tRNA-synt_1e PF01406.19 ORX91343.1 - 0.025 14.0 0.9 0.032 13.6 0.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Nucleos_tra2_C PF07662.13 ORX91344.1 - 2.2e-74 249.8 7.1 2.2e-74 249.8 7.1 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX91344.1 - 1.9e-23 82.9 3.4 1.9e-23 82.9 3.4 3.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus ABC_tran PF00005.27 ORX91344.1 - 7.5e-21 75.1 0.0 1.5e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX91344.1 - 1.2e-12 48.2 0.0 4.2e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORX91344.1 - 0.0022 17.7 0.2 0.0057 16.4 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ORX91344.1 - 0.0037 16.7 0.0 0.72 9.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 ORX91344.1 - 0.0046 15.7 0.2 1.1 7.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain Gate PF07670.14 ORX91344.1 - 0.011 16.0 8.6 0.011 16.0 8.6 4.1 3 2 0 3 3 3 0 Nucleoside recognition MukB PF04310.12 ORX91344.1 - 0.044 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_23 PF13476.6 ORX91344.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ORX91344.1 - 0.12 12.1 0.1 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORX91344.1 - 0.15 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF1128 PF06569.11 ORX91345.1 - 0.19 11.7 0.2 0.3 11.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1128) ABC_tran PF00005.27 ORX91346.1 - 1.9e-25 90.0 0.0 3.6e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX91346.1 - 3.2e-09 37.0 0.0 9.3e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORX91346.1 - 0.0019 18.0 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 ORX91346.1 - 0.0038 16.7 0.0 0.29 10.5 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 ORX91346.1 - 0.0093 15.7 0.0 0.92 9.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 ORX91346.1 - 0.02 15.3 1.4 0.17 12.3 0.3 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORX91346.1 - 0.028 14.9 1.5 0.057 13.9 1.5 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORX91346.1 - 0.033 13.5 0.0 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF4162 PF13732.6 ORX91346.1 - 0.15 12.8 0.2 0.6 10.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) TylF PF05711.11 ORX91346.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Chorismate_bind PF00425.18 ORX91347.1 - 5.3e-87 291.6 0.0 1.1e-86 290.6 0.0 1.6 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 ORX91347.1 - 9.4e-40 136.4 0.0 5.9e-38 130.5 0.1 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 ORX91347.1 - 7.6e-12 45.6 0.0 4.8e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 ORX91347.1 - 1.4e-06 28.2 0.1 2.8e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase C26 TIL PF01826.17 ORX91347.1 - 0.085 13.1 1.3 0.19 12.0 1.3 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain FHA PF00498.26 ORX91348.1 - 1.4e-15 57.4 0.2 4.1e-15 55.9 0.2 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORX91348.1 - 3.7e-10 40.0 0.0 2.5e-08 34.1 0.0 2.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NIBRIN_BRCT_II PF16508.5 ORX91348.1 - 7.6e-07 29.5 0.0 1.5e-05 25.3 0.0 2.7 1 1 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 PF16770.5 ORX91348.1 - 3e-05 23.8 0.1 7.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 ORX91348.1 - 0.0069 16.7 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nbs1_C PF08599.10 ORX91348.1 - 0.081 13.1 0.2 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 MU2_FHA PF18221.1 ORX91348.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Mutator 2 Fork head associated domain GTP_EFTU PF00009.27 ORX91349.1 - 3.5e-44 150.7 0.0 7.5e-44 149.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX91349.1 - 2e-34 118.3 0.0 6.4e-34 116.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX91349.1 - 1.1e-11 44.9 0.3 2.5e-11 43.8 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX91349.1 - 0.0056 16.8 0.1 0.038 14.1 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase LPD34 PF18852.1 ORX91349.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 GTP_EFTU_D4 PF14578.6 ORX91349.1 - 0.015 15.1 0.6 0.054 13.4 0.6 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 AAA_29 PF13555.6 ORX91349.1 - 0.18 11.6 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Yippee-Mis18 PF03226.14 ORX91350.1 - 1.6e-15 57.2 0.6 1.9e-15 56.9 0.6 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORX91350.1 - 0.027 14.7 1.9 0.045 14.0 1.9 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I LIM PF00412.22 ORX91350.1 - 0.042 14.1 1.2 1.6 9.1 0.5 2.2 2 0 0 2 2 2 0 LIM domain RhoGEF PF00621.20 ORX91351.1 - 1e-34 120.3 2.8 2.7e-34 119.0 2.8 1.7 1 0 0 1 1 1 1 RhoGEF domain ACOX PF01756.19 ORX91352.1 - 1.8e-51 174.3 0.0 3.1e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORX91352.1 - 5.5e-20 71.4 0.1 1.3e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORX91352.1 - 8.7e-17 61.8 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORX91352.1 - 4.3e-07 30.3 0.3 4.6e-06 26.9 0.1 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain G-patch PF01585.23 ORX91353.1 - 4.1e-08 33.0 1.4 8.3e-08 32.0 1.4 1.6 1 0 0 1 1 1 1 G-patch domain zf-met PF12874.7 ORX91353.1 - 5.9e-05 23.3 1.1 0.00013 22.2 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX91353.1 - 0.00059 20.0 5.8 0.00059 20.0 5.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORX91353.1 - 0.031 14.6 6.3 0.031 14.6 6.3 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) G-patch_2 PF12656.7 ORX91353.1 - 0.042 14.0 0.5 0.042 14.0 0.5 2.4 2 0 0 2 2 2 0 G-patch domain AKAP95 PF04988.12 ORX91353.1 - 0.046 14.0 10.7 0.086 13.1 10.6 1.5 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 ORX91353.1 - 0.14 12.7 5.8 0.23 12.0 1.8 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4820 PF16091.5 ORX91353.1 - 0.26 10.6 9.7 0.36 10.2 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_P4B PF03292.14 ORX91353.1 - 0.37 9.0 3.1 0.45 8.7 3.1 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Presenilin PF01080.17 ORX91353.1 - 1.6 7.4 9.5 1.8 7.3 9.5 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 ORX91353.1 - 3.4 4.7 9.5 4.1 4.4 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM217 PF15344.6 ORX91353.1 - 5 7.0 16.5 10 6.0 16.6 1.5 1 1 0 1 1 1 0 FAM217 family TMCO5 PF14992.6 ORX91353.1 - 6.4 6.3 15.4 8.1 5.9 15.4 1.1 1 0 0 1 1 1 0 TMCO5 family O-antigen_lig PF13425.6 ORX91353.1 - 9.5 4.9 8.7 12 4.6 8.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein WDCP PF15390.6 ORX91353.1 - 9.8 4.4 10.9 12 4.1 10.9 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SET PF00856.28 ORX91354.1 - 3e-22 79.8 0.0 5.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 ORX91354.1 - 2e-11 44.7 0.1 3.7e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding WBP-1 PF11669.8 ORX91361.1 - 0.00089 19.9 0.2 0.0023 18.6 0.2 1.7 1 0 0 1 1 1 1 WW domain-binding protein 1 Comm PF15957.5 ORX91361.1 - 0.0022 18.3 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Commissureless Shisa PF13908.6 ORX91361.1 - 0.046 14.0 0.4 0.068 13.4 0.0 1.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMIE PF16038.5 ORX91361.1 - 0.052 13.4 3.6 0.086 12.7 3.6 1.3 1 0 0 1 1 1 0 TMIE protein RCR PF12273.8 ORX91361.1 - 0.064 13.9 1.1 0.2 12.3 1.1 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SPRY PF00622.28 ORX91362.1 - 2.9e-17 62.9 0.0 3.1e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 SPRY domain DUF1883 PF08980.10 ORX91362.1 - 0.056 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) PGAP1 PF07819.13 ORX91363.1 - 5.7e-08 32.7 0.1 7.9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORX91363.1 - 1.1e-07 31.7 0.2 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Palm_thioest PF02089.15 ORX91363.1 - 1.4e-07 31.6 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 ORX91363.1 - 2.5e-05 25.0 0.6 2.9e-05 24.8 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 ORX91363.1 - 4.8e-05 22.7 0.0 7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 ORX91363.1 - 0.00045 19.6 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 ORX91363.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 ORX91363.1 - 0.011 15.3 0.0 0.013 15.2 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 ORX91363.1 - 0.032 13.5 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORX91363.1 - 0.051 13.1 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) UPF0227 PF05728.12 ORX91363.1 - 0.059 13.3 0.1 0.088 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 ORX91363.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_L22 PF00237.19 ORX91364.1 - 4.7e-43 145.6 0.1 6.1e-43 145.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PPTA PF01239.22 ORX91365.1 - 6.2e-38 127.5 11.3 5.5e-09 35.5 0.4 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat CBM_21 PF03370.13 ORX91366.1 - 4.1e-30 104.3 1.5 7.1e-30 103.5 1.5 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORX91366.1 - 9e-10 39.0 0.4 2e-09 37.9 0.4 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) SMC_N PF02463.19 ORX91367.1 - 3.2e-72 242.5 0.6 6.5e-72 241.5 0.6 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORX91367.1 - 9.9e-30 103.3 0.1 7.7e-29 100.4 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORX91367.1 - 4.4e-13 49.7 12.5 7.4e-07 29.3 1.2 3.9 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORX91367.1 - 2.8e-11 43.8 13.9 2.8e-11 43.8 13.9 4.7 2 2 2 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 ORX91367.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX91367.1 - 0.11 13.0 127.8 0.0085 16.6 62.6 6.8 2 2 1 3 3 3 0 AAA domain DUF87 PF01935.17 ORX91367.1 - 0.33 11.0 0.0 0.33 11.0 0.0 6.8 3 2 1 5 5 5 0 Helicase HerA, central domain Fasciclin PF02469.22 ORX91367.1 - 0.96 9.7 3.9 0.67 10.2 0.2 2.6 2 0 0 2 2 2 0 Fasciclin domain Voltage_CLC PF00654.20 ORX91368.1 - 4.5e-93 312.3 28.9 1.1e-92 311.0 27.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORX91368.1 - 4.4e-12 46.3 0.3 1.4e-06 28.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain RNase_Zc3h12a_2 PF14626.6 ORX91368.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Defensin_RK-1 PF17860.1 ORX91368.1 - 0.072 13.6 0.7 0.18 12.3 0.7 1.7 1 0 0 1 1 1 0 RK-1-like defensin MIF4G PF02854.19 ORX91369.1 - 2.6e-55 187.3 2.1 5e-55 186.4 2.1 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 ORX91369.1 - 6.3e-14 51.9 0.1 2e-13 50.3 0.1 1.9 1 0 0 1 1 1 1 MA3 domain eIF_4G1 PF12152.8 ORX91369.1 - 6.3e-09 35.9 0.0 2.9e-08 33.8 0.0 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF4404 PF14357.6 ORX91369.1 - 3.4 8.4 5.4 10 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) V-ATPase_H_N PF03224.14 ORX91370.1 - 4e-81 272.7 4.4 4e-81 272.7 4.4 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORX91370.1 - 4.2e-46 155.9 5.3 9.1e-45 151.6 0.2 3.2 3 1 0 3 3 3 2 V-ATPase subunit H HEAT PF02985.22 ORX91370.1 - 0.0043 17.2 0.4 0.79 10.1 0.0 3.2 2 0 0 2 2 2 1 HEAT repeat ParB PF08775.10 ORX91370.1 - 0.045 14.2 3.0 0.99 9.9 0.1 3.0 3 0 0 3 3 3 0 ParB family DUF1848 PF08902.11 ORX91370.1 - 0.11 12.1 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) PhoLip_ATPase_C PF16212.5 ORX91371.1 - 6.3e-87 291.4 27.5 6.3e-87 291.4 27.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX91371.1 - 6.4e-24 83.4 8.1 6.4e-24 83.4 8.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORX91371.1 - 2.4e-11 43.6 0.0 8.8e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX91371.1 - 3.3e-11 43.9 0.6 6.2e-06 26.6 0.1 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX91371.1 - 1.2e-08 34.8 0.4 3.9e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORX91371.1 - 0.0013 18.5 0.1 0.0073 16.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Orn_Arg_deC_N PF02784.16 ORX91372.1 - 7.1e-82 274.5 0.0 9.3e-82 274.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORX91372.1 - 4.9e-20 71.6 0.0 5.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Smg4_UPF3 PF03467.15 ORX91373.1 - 1.4e-58 197.8 0.3 1.4e-58 197.8 0.3 2.5 3 1 0 3 3 3 1 Smg-4/UPF3 family CDK2AP PF09806.9 ORX91373.1 - 0.048 13.7 1.6 0.087 12.9 1.6 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4685 PF15737.5 ORX91373.1 - 3.6 8.0 7.7 13 6.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Mis14 PF08641.12 ORX91374.1 - 1.5e-09 38.3 9.3 1.6e-08 35.0 1.9 2.9 1 1 2 3 3 3 2 Kinetochore protein Mis14 like DUF3834 PF12916.7 ORX91374.1 - 0.031 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Fcf1 PF04900.12 ORX91375.1 - 1.9e-29 101.9 0.0 3.5e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Fcf1 PLA2G12 PF06951.11 ORX91376.1 - 6.4e-08 32.7 4.9 8.1e-08 32.4 4.9 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) AGO_N PF18236.1 ORX91377.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Argonaute N domain Citrate_bind PF16114.5 ORX91379.1 - 2.3e-92 307.4 0.3 4.4e-92 306.4 0.3 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 ORX91379.1 - 1.1e-19 70.8 0.0 3e-17 62.7 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 ORX91379.1 - 1.6e-16 60.5 0.0 3.5e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 ORX91379.1 - 1.6e-13 51.1 0.0 5.1e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 ORX91379.1 - 5.6e-09 35.9 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ORX91379.1 - 3.6e-06 26.8 0.0 2.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain S36_mt PF10937.8 ORX91380.1 - 5.2e-10 40.9 0.4 7.4e-08 34.0 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial Band_7 PF01145.25 ORX91381.1 - 2.4e-22 79.8 4.7 3.4e-22 79.3 4.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_L18 PF17135.4 ORX91382.1 - 1.2e-97 324.8 3.2 1.3e-97 324.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORX91382.1 - 0.008 16.8 0.1 0.025 15.3 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AICARFT_IMPCHas PF01808.18 ORX91383.1 - 2.7e-93 312.7 0.0 4e-93 312.1 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ORX91383.1 - 8.2e-27 93.2 0.0 1.6e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Histone PF00125.24 ORX91384.1 - 3.1e-21 76.1 0.4 3.9e-21 75.8 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORX91384.1 - 5e-07 29.9 0.2 9.5e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORX91384.1 - 0.0011 19.5 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 ORX91384.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 ORX91384.1 - 0.0067 16.6 0.0 0.009 16.2 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein RP-C PF03428.13 ORX91384.1 - 0.097 12.3 0.6 7.5 6.2 0.0 2.0 1 1 1 2 2 2 0 Replication protein C N-terminal domain Metallophos PF00149.28 ORX91385.1 - 5.4e-13 49.9 0.5 7.6e-13 49.4 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TMEMspv1-c74-12 PF11044.8 ORX91385.1 - 0.0014 18.6 3.1 0.0031 17.4 3.1 1.6 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein 7TM_GPCR_Srx PF10328.9 ORX91385.1 - 0.031 13.9 0.2 0.056 13.1 0.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx PetL PF05115.14 ORX91385.1 - 0.13 12.2 0.3 0.13 12.2 0.3 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Proteasome PF00227.26 ORX91386.1 - 8.8e-47 159.0 0.3 1e-46 158.9 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit eIF2A PF08662.11 ORX91387.1 - 1.6e-86 289.1 0.7 7.4e-84 280.5 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORX91387.1 - 5.4e-05 23.4 0.5 0.014 15.7 0.0 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORX91387.1 - 0.0022 17.9 0.4 4.4 7.4 0.0 4.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat CDV3 PF15359.6 ORX91387.1 - 0.0044 17.5 0.8 0.0044 17.5 0.8 1.8 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 WD40 PF00400.32 ORX91387.1 - 0.017 16.0 0.1 11 7.1 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Complex1_LYR_2 PF13233.6 ORX91387.1 - 0.22 12.3 1.5 0.53 11.1 0.9 1.9 2 0 0 2 2 2 0 Complex1_LYR-like Spindle_Spc25 PF08234.12 ORX91388.1 - 8.5e-24 83.6 1.8 1.1e-23 83.2 0.4 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 PMC2NT PF08066.12 ORX91388.1 - 0.0061 17.2 1.1 0.022 15.4 1.0 2.1 1 1 0 1 1 1 1 PMC2NT (NUC016) domain Bacillus_HBL PF05791.11 ORX91388.1 - 0.0077 16.1 2.4 0.0077 16.1 2.4 2.6 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF2026 PF09641.10 ORX91388.1 - 0.053 13.2 0.2 0.1 12.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) Spc7 PF08317.11 ORX91388.1 - 0.071 12.0 14.3 0.097 11.5 14.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LMBR1 PF04791.16 ORX91388.1 - 0.14 11.0 4.6 0.16 10.9 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 ORX91388.1 - 0.18 11.1 10.8 0.24 10.6 10.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 ORX91388.1 - 0.39 9.8 15.7 0.56 9.2 15.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 ORX91388.1 - 0.4 10.2 6.0 0.48 9.9 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 ORX91388.1 - 0.81 8.9 13.7 1.3 8.2 13.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 ORX91388.1 - 2.1 6.2 7.8 2.5 5.9 7.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 ORX91388.1 - 2.5 8.2 7.0 1.3 9.1 1.3 2.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 ORX91388.1 - 2.9 7.2 6.7 3.9 6.7 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kinesin_assoc PF16183.5 ORX91388.1 - 5.2 7.2 10.1 0.21 11.7 1.6 2.1 1 1 1 2 2 2 0 Kinesin-associated FlxA PF14282.6 ORX91388.1 - 8.7 6.4 16.7 7.4 6.6 14.4 1.9 1 1 1 2 2 2 0 FlxA-like protein LPMO_10 PF03067.15 ORX91389.1 - 4.2e-05 24.3 0.0 7e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX91389.1 - 0.0015 18.5 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX91390.1 - 0.00014 22.6 0.0 0.00028 21.6 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_5_12 PF02839.14 ORX91390.1 - 0.002 18.6 7.5 0.0065 17.0 7.5 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_61 PF03443.14 ORX91390.1 - 0.0051 16.8 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 CBM_5_12_2 PF14600.6 ORX91390.1 - 0.006 16.5 2.8 0.015 15.2 2.8 1.7 1 0 0 1 1 1 1 Cellulose-binding domain UPF0506 PF11703.8 ORX91391.1 - 0.00081 19.7 5.7 0.001 19.4 5.7 1.2 1 0 0 1 1 1 1 UPF0506 Toxin_29 PF08116.11 ORX91391.1 - 0.0036 17.3 6.7 0.0051 16.8 6.7 1.2 1 0 0 1 1 1 1 PhTx neurotoxin family Conotoxin_I2 PF17557.2 ORX91391.1 - 0.01 15.9 9.4 0.012 15.7 9.4 1.3 1 0 0 1 1 1 0 I2-superfamily conotoxins Pkinase_Tyr PF07714.17 ORX91397.1 - 1.5e-41 142.5 0.0 2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORX91397.1 - 3.1e-28 98.9 0.0 4.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORX91397.1 - 0.0016 17.8 0.0 0.92 8.8 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Rx_N PF18052.1 ORX91397.1 - 0.18 12.1 0.3 0.69 10.2 0.1 2.0 2 0 0 2 2 2 0 Rx N-terminal domain Tnp_zf-ribbon_2 PF13842.6 ORX91397.1 - 8.2 7.3 13.9 24 5.9 13.9 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Sortilin-Vps10 PF15902.5 ORX91398.1 - 0 1404.1 12.2 2e-150 501.5 1.7 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ORX91398.1 - 2e-134 444.8 37.1 1.4e-48 165.5 5.4 4.5 4 0 0 4 4 4 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 ORX91398.1 - 3.7e-12 44.3 59.3 1.4 9.2 0.3 16.5 18 0 0 18 18 18 9 BNR/Asp-box repeat PSII_BNR PF14870.6 ORX91398.1 - 0.00098 18.5 9.6 3.2 6.9 0.1 6.5 6 3 0 6 6 6 2 Photosynthesis system II assembly factor YCF48 DUF4988 PF16378.5 ORX91398.1 - 0.0018 18.0 0.1 0.85 9.3 0.1 4.3 4 0 0 4 4 4 1 Domain of unknown function S1-P1_nuclease PF02265.16 ORX91406.1 - 3.3e-54 184.4 0.0 3.9e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease EST1_DNA_bind PF10373.9 ORX91407.1 - 2.6e-10 40.3 0.1 3.8e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Abhydrolase_1 PF00561.20 ORX91409.1 - 7.9e-11 42.1 0.1 5.1e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX91409.1 - 6.2e-08 32.2 0.0 2e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX91409.1 - 2.7e-05 24.9 0.0 3.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORX91409.1 - 9e-05 22.5 0.0 0.018 15.0 0.0 2.2 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ORX91409.1 - 0.0029 16.3 0.1 0.02 13.6 0.1 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ORX91409.1 - 0.0053 16.3 0.0 0.056 13.0 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ORX91409.1 - 0.022 14.2 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF818 PF05677.12 ORX91409.1 - 0.042 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 ORX91409.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 ORX91409.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CBM9_1 PF06452.11 ORX91410.1 - 3.2e-11 43.5 0.0 9.1e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_1 PF06452.11 ORX91411.1 - 5e-11 42.8 1.0 6.9e-11 42.4 0.2 1.6 2 0 0 2 2 2 1 Carbohydrate family 9 binding domain-like Epimerase PF01370.21 ORX91412.1 - 5e-28 98.2 0.0 6.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX91412.1 - 3.4e-19 69.4 0.0 1.2e-17 64.3 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORX91412.1 - 8e-14 51.4 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX91412.1 - 3.4e-10 39.4 0.0 4.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX91412.1 - 3e-07 29.9 0.0 1.6e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORX91412.1 - 3e-07 29.9 0.1 3.6e-06 26.3 0.1 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORX91412.1 - 0.12 12.3 0.1 9.9 6.0 0.0 2.3 2 0 0 2 2 2 0 KR domain SNO PF01174.19 ORX91414.1 - 2e-54 184.3 0.0 2.3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORX91414.1 - 1.1e-11 44.6 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 ORX91414.1 - 0.00011 22.1 0.0 0.00044 20.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 ORX91414.1 - 0.0023 17.6 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family S51 DJ-1_PfpI PF01965.24 ORX91414.1 - 0.034 14.0 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family WD40 PF00400.32 ORX91415.1 - 1.2e-10 41.8 5.9 0.16 12.9 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91415.1 - 6.7e-07 29.5 0.0 0.33 11.3 0.0 4.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX91415.1 - 7.1e-05 21.9 0.1 0.0035 16.3 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX91415.1 - 0.0087 14.7 1.3 0.043 12.5 1.3 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DPPIV_N PF00930.21 ORX91415.1 - 0.061 12.1 0.9 1 8.0 0.1 2.2 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Septin PF00735.18 ORX91416.1 - 5.7e-97 324.4 0.3 5.7e-97 324.4 0.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORX91416.1 - 9.7e-09 35.3 0.1 9.7e-09 35.3 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX91416.1 - 4.1e-06 26.8 0.2 0.00059 19.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ORX91416.1 - 4.7e-05 23.7 2.1 0.00053 20.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 ORX91416.1 - 5.4e-05 22.7 1.3 0.037 13.4 0.0 2.2 2 0 0 2 2 2 2 FtsK/SpoIIIE family AIG1 PF04548.16 ORX91416.1 - 0.00067 19.1 0.0 0.00067 19.1 0.0 2.2 2 1 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 ORX91416.1 - 0.0047 16.5 6.4 0.06 12.9 0.4 3.4 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 ORX91416.1 - 0.0076 15.3 0.5 0.061 12.4 0.0 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.12 ORX91416.1 - 0.0089 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 ORX91416.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORX91416.1 - 0.015 15.7 0.1 0.074 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 ORX91416.1 - 0.021 15.2 0.0 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase HAUS6_N PF14661.6 ORX91416.1 - 0.021 14.4 5.2 0.035 13.7 5.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus T2SSE PF00437.20 ORX91416.1 - 0.022 13.8 0.8 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 ORX91416.1 - 0.034 14.3 2.3 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 ORX91416.1 - 0.037 13.8 0.2 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORX91416.1 - 0.039 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 ORX91416.1 - 0.063 13.0 2.3 0.12 12.1 0.4 2.5 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 ORX91416.1 - 0.07 12.3 1.1 0.16 11.1 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain Ras PF00071.22 ORX91416.1 - 0.077 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Ras family Spond_N PF06468.13 ORX91416.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Spondin_N ABC_tran PF00005.27 ORX91416.1 - 0.13 12.8 1.0 0.62 10.6 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Dynamin_N PF00350.23 ORX91416.1 - 0.13 12.3 9.5 1.4 9.0 0.0 3.5 2 2 1 3 3 3 0 Dynamin family Nucleoporin2 PF04096.14 ORX91416.1 - 0.18 11.9 3.1 8.3 6.5 0.0 2.8 3 0 0 3 3 2 0 Nucleoporin autopeptidase LMP PF04778.12 ORX91416.1 - 0.41 10.5 7.9 0.75 9.7 7.9 1.4 1 0 0 1 1 1 0 LMP repeated region OmpH PF03938.14 ORX91416.1 - 1.1 9.6 17.8 2.4 8.5 17.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PBP_sp32 PF07222.12 ORX91416.1 - 1.8 7.9 8.8 3 7.2 8.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AAA_11 PF13086.6 ORX91416.1 - 3.5 7.3 7.6 1.6 8.5 5.3 1.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORX91416.1 - 3.7 6.6 11.1 6.8 5.7 0.0 3.2 2 2 0 3 3 3 0 G-protein alpha subunit RSN1_7TM PF02714.15 ORX91417.1 - 8e-69 232.0 29.3 9.9e-69 231.7 29.3 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX91417.1 - 2.7e-09 37.5 0.0 4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Sensor PF13796.6 ORX91417.1 - 0.23 11.5 6.6 0.4 10.7 0.0 3.2 1 1 2 3 3 3 0 Putative sensor TssO PF17561.2 ORX91417.1 - 0.27 11.3 1.7 0.6 10.2 0.6 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF2207 PF09972.9 ORX91417.1 - 4.5 5.9 12.7 73 1.9 0.2 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) zinc_ribbon_16 PF17034.5 ORX91418.1 - 2.4e-14 53.6 2.2 4.5e-14 52.7 2.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 ORX91418.1 - 7.2e-05 23.5 0.1 0.84 10.6 0.0 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Mog1 PF04603.12 ORX91419.1 - 1.1e-43 149.0 0.8 1.3e-43 148.7 0.8 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SH3_2 PF07653.17 ORX91420.1 - 0.0036 16.9 0.1 0.0079 15.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.6 ORX91420.1 - 0.022 13.6 0.1 0.14 10.9 0.1 1.9 2 0 0 2 2 2 0 Amnionless LRRNT_2 PF08263.12 ORX91420.1 - 0.072 13.4 9.4 0.19 12.1 9.4 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Syndecan PF01034.20 ORX91420.1 - 0.094 12.6 1.6 0.18 11.8 1.6 1.3 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 ORX91420.1 - 0.11 12.5 0.6 0.18 11.8 0.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J NAD_Gly3P_dh_N PF01210.23 ORX91421.1 - 7.9e-49 165.6 0.1 1.2e-48 165.0 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORX91421.1 - 4.3e-40 137.3 0.2 1.6e-39 135.4 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORX91421.1 - 0.033 14.8 0.1 4.6 7.9 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent UPF0242 PF06785.11 ORX91422.1 - 1.1e-05 25.7 7.5 1.2e-05 25.5 7.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 ORX91422.1 - 7.4e-05 22.8 14.6 0.03 14.4 5.4 2.2 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 ORX91422.1 - 8e-05 22.9 7.6 0.00016 21.9 7.0 1.8 1 1 1 2 2 1 1 Tup N-terminal CENP-F_leu_zip PF10473.9 ORX91422.1 - 0.00011 22.2 12.3 0.00016 21.7 12.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 ORX91422.1 - 0.00014 20.9 11.5 0.00017 20.6 11.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MAD PF05557.13 ORX91422.1 - 0.00014 20.4 6.3 0.00019 20.0 6.3 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Atg14 PF10186.9 ORX91422.1 - 0.00067 18.8 7.4 0.00078 18.6 7.4 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HrpB7 PF09486.10 ORX91422.1 - 0.0007 20.0 4.9 0.002 18.5 4.9 1.6 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) NOG1_N PF17835.1 ORX91422.1 - 0.0009 19.2 1.7 0.0013 18.7 0.8 1.6 1 1 1 2 2 2 1 NOG1 N-terminal helical domain Syntaxin PF00804.25 ORX91422.1 - 0.0012 18.5 8.6 0.0019 17.9 8.5 1.3 1 1 0 1 1 1 1 Syntaxin Leu_zip PF15294.6 ORX91422.1 - 0.0016 18.0 7.2 0.002 17.7 7.2 1.2 1 0 0 1 1 1 1 Leucine zipper DivIC PF04977.15 ORX91422.1 - 0.0019 17.9 8.9 0.0039 16.9 3.2 2.7 1 1 2 3 3 3 1 Septum formation initiator SlyX PF04102.12 ORX91422.1 - 0.0022 18.6 8.8 0.61 10.7 0.3 3.1 1 1 2 3 3 3 2 SlyX Hrs_helical PF12210.8 ORX91422.1 - 0.0023 18.4 4.7 0.063 13.8 1.1 2.2 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate MAP65_ASE1 PF03999.12 ORX91422.1 - 0.0024 16.7 4.6 0.0033 16.2 4.6 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Exonuc_VII_L PF02601.15 ORX91422.1 - 0.0025 17.5 2.9 0.0033 17.0 2.9 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit TMPIT PF07851.13 ORX91422.1 - 0.0026 17.1 6.4 0.0031 16.8 6.4 1.1 1 0 0 1 1 1 1 TMPIT-like protein DUF724 PF05266.14 ORX91422.1 - 0.0027 17.6 5.4 0.0035 17.2 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) GAS PF13851.6 ORX91422.1 - 0.0036 16.7 10.5 0.0047 16.3 10.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding WEMBL PF05701.11 ORX91422.1 - 0.0061 15.3 10.5 0.039 12.7 10.5 1.8 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Uds1 PF15456.6 ORX91422.1 - 0.0062 16.7 9.4 0.0082 16.3 9.4 1.1 1 0 0 1 1 1 1 Up-regulated During Septation FlaC_arch PF05377.11 ORX91422.1 - 0.0063 16.9 7.7 1.8 9.0 0.5 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Gp58 PF07902.11 ORX91422.1 - 0.0077 14.6 1.0 0.0086 14.4 1.0 1.1 1 0 0 1 1 1 1 gp58-like protein Allexi_40kDa PF05549.11 ORX91422.1 - 0.0081 15.7 2.3 0.0098 15.4 2.3 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein Phage_HK97_TLTM PF06120.11 ORX91422.1 - 0.0093 15.2 7.2 0.012 14.9 7.2 1.1 1 0 0 1 1 1 1 Tail length tape measure protein HMMR_N PF15905.5 ORX91422.1 - 0.0099 15.4 9.7 0.012 15.1 9.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DASH_Duo1 PF08651.10 ORX91422.1 - 0.011 15.5 3.6 0.34 10.7 0.5 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF3584 PF12128.8 ORX91422.1 - 0.013 13.1 7.3 0.015 12.9 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 ORX91422.1 - 0.02 12.9 1.6 0.022 12.8 1.6 1.0 1 0 0 1 1 1 0 Prominin Tropomyosin PF00261.20 ORX91422.1 - 0.02 14.2 9.9 0.027 13.9 9.9 1.2 1 0 0 1 1 1 0 Tropomyosin Fez1 PF06818.15 ORX91422.1 - 0.021 15.3 10.6 0.031 14.8 8.5 1.8 1 1 1 2 2 2 0 Fez1 GLE1 PF07817.13 ORX91422.1 - 0.024 13.9 3.9 0.033 13.4 3.5 1.4 1 1 0 1 1 1 0 GLE1-like protein LRS4 PF10422.9 ORX91422.1 - 0.026 14.1 8.9 0.032 13.8 8.9 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4972 PF16342.5 ORX91422.1 - 0.027 14.2 0.5 0.046 13.4 0.1 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4972) Sec8_exocyst PF04048.14 ORX91422.1 - 0.028 14.3 9.1 0.43 10.5 2.0 2.8 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 ORX91422.1 - 0.028 14.5 6.2 0.16 12.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 ORX91422.1 - 0.035 13.7 11.4 1.3 8.6 11.4 2.0 1 1 0 1 1 1 0 PspA/IM30 family FliJ PF02050.16 ORX91422.1 - 0.035 14.3 11.5 0.097 12.9 11.6 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein Spc24 PF08286.11 ORX91422.1 - 0.037 14.3 11.3 0.075 13.3 2.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 ORX91422.1 - 0.037 14.4 13.7 0.46 10.9 0.2 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain Sec2p PF06428.11 ORX91422.1 - 0.039 13.9 12.6 0.15 12.0 0.5 2.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Fur_reg_FbpB PF13040.6 ORX91422.1 - 0.04 13.5 3.6 0.048 13.2 0.2 2.6 2 1 1 3 3 3 0 Fur-regulated basic protein B FapA PF03961.13 ORX91422.1 - 0.041 12.5 5.5 0.05 12.2 5.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CALCOCO1 PF07888.11 ORX91422.1 - 0.049 12.5 9.3 0.06 12.2 9.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF948 PF06103.11 ORX91422.1 - 0.05 13.9 2.2 0.4 11.0 1.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HemX PF04375.14 ORX91422.1 - 0.056 12.7 10.4 0.39 10.0 10.4 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase KxDL PF10241.9 ORX91422.1 - 0.065 13.5 8.3 0.098 13.0 2.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF4407 PF14362.6 ORX91422.1 - 0.069 12.5 3.0 0.096 12.0 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 ORX91422.1 - 0.069 12.7 11.7 0.36 10.3 11.6 1.8 1 1 0 1 1 1 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 ORX91422.1 - 0.07 13.4 8.7 0.097 12.9 8.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 ORX91422.1 - 0.071 13.3 9.6 0.1 12.9 8.5 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NRBF2 PF08961.10 ORX91422.1 - 0.089 12.4 10.6 0.84 9.2 2.7 2.4 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HIP1_clath_bdg PF16515.5 ORX91422.1 - 0.089 13.4 12.4 0.11 13.1 9.6 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 ORX91422.1 - 0.093 12.7 16.5 0.57 10.2 1.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.5 ORX91422.1 - 0.11 12.6 8.3 0.53 10.4 1.4 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF3450 PF11932.8 ORX91422.1 - 0.15 11.4 12.1 0.19 11.0 9.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF745 PF05335.13 ORX91422.1 - 0.18 11.5 6.9 0.31 10.7 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF4795 PF16043.5 ORX91422.1 - 0.19 11.3 8.6 0.28 10.8 8.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 ORX91422.1 - 0.2 11.8 9.8 0.78 9.9 9.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 ORX91422.1 - 0.2 12.1 8.1 0.31 11.5 4.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF2203 PF09969.9 ORX91422.1 - 0.2 12.3 6.2 0.69 10.6 5.9 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mto2_bdg PF12808.7 ORX91422.1 - 0.21 11.9 0.4 0.21 11.9 0.4 2.6 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MscS_porin PF12795.7 ORX91422.1 - 0.24 10.9 13.6 1.8 8.1 13.9 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 ORX91422.1 - 0.24 11.6 14.1 0.11 12.7 7.6 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TBCA PF02970.16 ORX91422.1 - 0.26 11.6 10.0 4.4 7.7 10.0 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor A YabA PF06156.13 ORX91422.1 - 0.27 11.9 8.3 1.1 9.9 8.3 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Med9 PF07544.13 ORX91422.1 - 0.29 11.3 12.1 0.36 11.0 5.8 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3958 PF13125.6 ORX91422.1 - 0.31 11.2 9.8 0.85 9.9 9.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) PRKG1_interact PF15898.5 ORX91422.1 - 0.33 11.9 12.1 0.95 10.4 1.8 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 ORX91422.1 - 0.33 8.8 4.4 0.39 8.6 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5082 PF16888.5 ORX91422.1 - 0.34 11.2 10.3 1.2 9.4 10.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) MTBP_C PF14920.6 ORX91422.1 - 0.35 10.6 4.9 0.37 10.5 4.4 1.2 1 1 0 1 1 1 0 MDM2-binding HR1 PF02185.16 ORX91422.1 - 0.36 11.0 15.0 0.56 10.4 1.5 3.2 1 1 1 2 2 2 0 Hr1 repeat ADIP PF11559.8 ORX91422.1 - 0.37 10.9 13.6 1.2 9.3 3.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 ORX91422.1 - 0.38 11.3 10.3 0.86 10.1 4.7 2.1 1 1 1 2 2 2 0 Spectrin repeat Chibby PF14645.6 ORX91422.1 - 0.39 11.1 4.3 0.22 11.9 1.6 1.8 1 1 1 2 2 1 0 Chibby family CCDC-167 PF15188.6 ORX91422.1 - 0.43 11.0 6.8 4.3 7.7 1.0 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Phage_lysis PF03245.13 ORX91422.1 - 0.52 10.4 6.7 0.47 10.6 5.2 1.5 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF5339 PF17274.2 ORX91422.1 - 0.53 11.2 8.4 13 6.7 0.4 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5339) YlqD PF11068.8 ORX91422.1 - 0.55 10.6 10.4 1.3 9.4 10.6 1.6 1 1 0 1 1 1 0 YlqD protein DUF16 PF01519.16 ORX91422.1 - 0.55 10.7 10.3 22 5.6 10.4 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 FliD_N PF02465.18 ORX91422.1 - 0.61 10.8 7.2 2.9 8.6 7.2 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Rho_Binding PF08912.11 ORX91422.1 - 0.69 10.8 12.4 2.1 9.2 5.2 2.4 1 1 1 2 2 2 0 Rho Binding Occludin_ELL PF07303.13 ORX91422.1 - 0.73 10.6 7.1 0.97 10.2 3.2 2.1 1 1 1 2 2 2 0 Occludin homology domain APG6_N PF17675.1 ORX91422.1 - 0.81 10.2 13.3 0.44 11.1 9.0 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 ORX91422.1 - 0.84 10.1 13.8 1.5 9.3 13.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) JIP_LZII PF16471.5 ORX91422.1 - 0.9 9.8 7.8 0.33 11.2 2.8 2.4 1 1 0 2 2 1 0 JNK-interacting protein leucine zipper II SseC PF04888.12 ORX91422.1 - 0.91 9.1 4.3 0.85 9.2 3.4 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family COMP PF11598.8 ORX91422.1 - 0.93 10.0 4.1 4.3 7.9 0.1 2.4 1 1 0 2 2 2 0 Cartilage oligomeric matrix protein Cnn_1N PF07989.11 ORX91422.1 - 0.98 9.6 11.8 1.6 9.0 5.0 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 V-SNARE PF05008.15 ORX91422.1 - 1.1 9.7 12.5 0.44 11.0 4.7 2.6 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DHR10 PF18595.1 ORX91422.1 - 1.6 8.8 14.9 2.8 8.0 14.9 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain FemAB PF02388.16 ORX91422.1 - 1.7 7.4 8.1 2.5 6.9 7.0 1.6 1 1 0 1 1 1 0 FemAB family DUF4763 PF15960.5 ORX91422.1 - 1.8 7.8 10.8 1.7 7.9 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) USP8_interact PF08941.10 ORX91422.1 - 2.6 7.8 5.5 34 4.2 5.5 2.3 1 1 0 1 1 1 0 USP8 interacting FOXP-CC PF16159.5 ORX91422.1 - 3.2 8.4 4.5 6.6 7.4 0.6 2.6 1 1 2 3 3 3 0 FOXP coiled-coil domain CENP-H PF05837.12 ORX91422.1 - 3.3 8.2 11.5 6.4 7.2 11.5 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Swi5 PF07061.11 ORX91422.1 - 4 7.6 10.7 16 5.6 5.2 2.6 1 1 1 2 2 2 0 Swi5 DUF4140 PF13600.6 ORX91422.1 - 5 7.6 9.1 3.1 8.3 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 ORX91422.1 - 8.1 7.0 14.5 57 4.2 14.5 2.2 1 1 0 1 1 1 0 Cell division protein ZapB RGS PF00615.19 ORX91423.1 - 1.2e-13 51.4 4.3 2.2e-13 50.5 4.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX91423.1 - 6.4e-05 22.8 13.3 0.00021 21.1 13.3 1.8 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CTP_transf_like PF01467.26 ORX91424.1 - 1.5e-07 31.7 0.0 2.5e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like Arrestin_C PF02752.22 ORX91426.1 - 4.8e-10 40.0 3.3 4.4e-08 33.7 0.5 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX91426.1 - 8.8e-09 35.6 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX91426.1 - 0.03 13.5 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Rgp1 UAA PF08449.11 ORX91430.1 - 1.7e-99 332.8 17.7 2e-99 332.6 17.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ORX91430.1 - 8.4e-07 28.4 6.6 2.5e-06 26.9 1.0 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter PUNUT PF16913.5 ORX91430.1 - 1.3e-06 27.9 16.7 7.7e-06 25.3 16.7 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 ORX91430.1 - 0.00014 22.1 27.4 0.011 15.9 3.1 3.5 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 ORX91430.1 - 0.0011 18.3 13.9 0.011 15.2 2.4 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 ORX91430.1 - 0.024 13.6 19.9 0.26 10.2 19.9 2.1 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Ribosomal_60s PF00428.19 ORX91431.1 - 1.3e-24 86.5 8.5 1.8e-24 86.1 8.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein ATG16 PF08614.11 ORX91432.1 - 0.0099 16.1 21.2 0.0099 16.1 21.2 4.1 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 ORX91432.1 - 0.01 15.9 40.6 0.16 12.0 4.3 4.4 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 ORX91432.1 - 0.012 15.6 1.9 0.012 15.6 1.9 5.1 5 1 0 5 5 5 0 TolA binding protein trimerisation PRKG1_interact PF15898.5 ORX91432.1 - 0.018 15.9 12.5 0.018 15.9 12.5 4.8 3 2 2 5 5 5 0 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 ORX91432.1 - 2.5 8.4 20.0 1.4 9.2 1.7 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF4407 PF14362.6 ORX91432.1 - 3.1 7.0 23.2 6 6.1 11.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MscS_porin PF12795.7 ORX91432.1 - 6.4 6.2 34.2 0.1 12.2 22.6 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CNH PF00780.22 ORX91433.1 - 3.1e-76 256.6 0.0 5.3e-76 255.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORX91433.1 - 3.3e-37 128.5 0.0 7.1e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORX91433.1 - 2.8e-29 101.9 0.0 5.7e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORX91433.1 - 3.2e-15 55.9 0.1 7.4e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 ORX91433.1 - 0.022 15.3 0.0 0.095 13.2 0.0 2.1 2 0 0 2 2 2 0 PH domain CMS1 PF14617.6 ORX91434.1 - 4.7e-47 160.4 2.3 5.6e-47 160.2 2.3 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 ORX91434.1 - 0.00027 20.8 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4770 PF15994.5 ORX91434.1 - 0.015 15.5 2.5 1.8 8.8 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) GAGA_bind PF06217.12 ORX91434.1 - 0.027 14.8 1.1 0.044 14.1 1.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PTPRCAP PF15713.5 ORX91434.1 - 2.1 8.6 6.5 3.2 8.0 6.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated YqfQ PF14181.6 ORX91434.1 - 2.2 8.5 5.2 4.3 7.5 5.2 1.5 1 0 0 1 1 1 0 YqfQ-like protein Proteasome PF00227.26 ORX91435.1 - 1.1e-53 181.6 0.0 1.5e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORX91435.1 - 1.7e-15 56.4 0.1 3.7e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TPP_enzyme_N PF02776.18 ORX91436.1 - 1.3e-46 158.3 0.2 3.1e-42 144.1 0.0 3.3 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORX91436.1 - 2.3e-35 121.3 0.3 1.4e-34 118.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORX91436.1 - 2.1e-26 92.6 0.1 8.1e-26 90.6 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORX91436.1 - 0.00019 20.7 0.3 0.00042 19.6 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.16 ORX91436.1 - 0.00076 19.3 0.0 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit E1_dh PF00676.20 ORX91436.1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component Sec2p PF06428.11 ORX91437.1 - 1.2e-16 60.4 8.7 1.2e-16 60.4 8.7 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p zf-FLZ PF04570.14 ORX91437.1 - 0.011 15.2 0.5 0.011 15.2 0.5 2.6 1 1 1 2 2 2 0 zinc-finger of the FCS-type, C2-C2 kleA_kleC PF17383.2 ORX91437.1 - 5.3 7.5 5.6 2 8.8 0.8 2.6 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A UCR_14kD PF02271.16 ORX91439.1 - 1.8e-41 140.2 0.5 2.1e-41 140.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MMS1_N PF10433.9 ORX91440.1 - 2.8e-109 366.0 0.0 4.8e-109 365.2 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORX91440.1 - 8.7e-76 255.3 0.1 2.1e-75 254.0 0.1 1.7 1 0 0 1 1 1 1 CPSF A subunit region Adaptin_N PF01602.20 ORX91441.1 - 6.1e-46 157.1 4.9 8.3e-46 156.6 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORX91441.1 - 5.1e-19 68.9 1.4 1e-17 64.7 0.0 2.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX91441.1 - 8.2e-06 26.1 0.1 0.00016 22.0 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats CLASP_N PF12348.8 ORX91441.1 - 0.00034 20.2 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 ORX91441.1 - 0.019 15.2 0.8 2.5 8.6 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Ribosomal_S6e PF01092.19 ORX91442.1 - 1.9e-60 202.4 0.0 3.7e-60 201.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e LPMO_10 PF03067.15 ORX91443.1 - 6.3e-07 30.2 0.3 2.9e-06 28.1 0.1 2.1 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX91443.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 PPR_2 PF13041.6 ORX91444.1 - 1.5e-20 73.1 8.2 1.2e-06 28.7 0.3 5.8 6 2 2 8 8 7 4 PPR repeat family PPR PF01535.20 ORX91444.1 - 7.2e-18 63.5 7.0 0.012 15.9 0.0 6.2 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 ORX91444.1 - 3.5e-13 49.4 1.4 2.3e-06 27.1 0.3 3.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 ORX91444.1 - 1.3e-09 38.0 1.7 0.13 12.4 0.0 5.3 4 2 1 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX91444.1 - 1.2e-06 28.0 1.7 0.032 13.9 0.0 4.2 5 0 0 5 5 5 2 PPR repeat TPR_19 PF14559.6 ORX91444.1 - 0.0002 21.8 0.0 4.9 7.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat FANCI_HD1 PF14679.6 ORX91444.1 - 0.0019 18.2 0.2 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 FANCI helical domain 1 ANAPC3 PF12895.7 ORX91444.1 - 0.004 17.3 0.8 8.2 6.7 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.20 ORX91444.1 - 0.0053 16.6 0.2 12 5.8 0.0 3.8 3 1 1 4 4 4 0 Region in Clathrin and VPS MNE1 PF13762.6 ORX91444.1 - 0.009 16.0 0.2 0.92 9.5 0.0 3.2 3 1 0 3 3 3 1 Mitochondrial splicing apparatus component TPR_14 PF13428.6 ORX91444.1 - 0.0093 16.7 0.0 18 6.5 0.0 4.4 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX91444.1 - 0.014 15.4 1.3 1.6 9.0 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Mic1 PF07035.12 ORX91444.1 - 0.025 14.3 0.3 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 Colon cancer-associated protein Mic1-like TPR_15 PF13429.6 ORX91444.1 - 0.029 13.6 0.1 1.1 8.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RE_CfrBI PF09516.10 ORX91444.1 - 0.045 13.2 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 CfrBI restriction endonuclease MOR2-PAG1_C PF14225.6 ORX91444.1 - 0.055 13.3 1.7 2 8.2 0.1 2.8 2 1 0 2 2 2 0 Cell morphogenesis C-terminal Sa_NUDIX PF18167.1 ORX91444.1 - 0.095 12.5 1.2 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 SMODS-associated NUDIX domain RTP1_C1 PF10363.9 ORX91444.1 - 0.1 12.8 0.2 1.8 8.8 0.0 2.6 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_7 PF13176.6 ORX91444.1 - 0.11 12.6 0.1 9.5 6.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 ORX91444.1 - 0.13 12.7 0.0 1.2 9.5 0.0 2.3 2 1 0 2 2 2 0 Bacterial transcriptional activator domain RPAP3_C PF13877.6 ORX91444.1 - 0.17 12.5 1.6 1.1 9.9 0.0 3.0 3 1 1 4 4 4 0 Potential Monad-binding region of RPAP3 RGS PF00615.19 ORX91445.1 - 4.9e-18 65.5 0.2 5.7e-18 65.3 0.2 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORX91445.1 - 6.8e-05 22.7 0.1 7.1e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain Phage_holin_3_6 PF07332.11 ORX91446.1 - 0.84 9.7 2.7 1.1 9.3 2.7 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Sec1 PF00995.23 ORX91447.1 - 1.1e-118 398.0 0.2 1.2e-118 397.9 0.2 1.0 1 0 0 1 1 1 1 Sec1 family DUF2115 PF09888.9 ORX91447.1 - 0.19 12.2 2.1 3.2 8.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Cyclin PF08613.11 ORX91448.1 - 1.5e-12 48.2 0.1 1.7e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX91448.1 - 4.7e-12 45.8 0.1 5.4e-12 45.6 0.1 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain TMEM234 PF10639.9 ORX91449.1 - 1.2e-43 147.8 0.7 1.4e-43 147.6 0.7 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 ORX91449.1 - 1.8e-09 37.9 3.5 5.2e-07 29.9 2.6 2.0 1 1 1 2 2 2 2 EamA-like transporter family Ureide_permease PF07168.11 ORX91449.1 - 0.056 12.2 1.5 0.084 11.6 1.4 1.4 1 1 1 2 2 2 0 Ureide permease Cyclin_N PF00134.23 ORX91450.1 - 7.5e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX91450.1 - 7.6e-12 45.9 0.0 9.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin LCD1 PF09798.9 ORX91450.1 - 0.035 12.6 0.1 0.047 12.2 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Tetraspanin PF00335.20 ORX91451.1 - 0.24 11.1 9.6 0.2 11.3 7.5 1.7 1 1 1 2 2 2 0 Tetraspanin family Kei1 PF08552.11 ORX91451.1 - 5.1 6.9 15.3 0.89 9.4 8.3 2.0 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Sugar_tr PF00083.24 ORX91452.1 - 9.5e-71 239.0 16.1 1.1e-70 238.8 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX91452.1 - 7.2e-15 54.8 16.9 2.8e-13 49.5 13.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.28 ORX91454.1 - 9.7e-12 45.1 0.1 3e-11 43.5 0.0 1.8 1 1 1 2 2 2 1 NUDIX domain DUF2664 PF10867.8 ORX91454.1 - 0.13 12.7 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) DUF4210 PF13915.6 ORX91455.1 - 6.5e-32 109.9 0.9 2e-31 108.4 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ORX91455.1 - 3.4e-24 84.8 0.1 9.4e-24 83.3 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis ATG13 PF10033.9 ORX91455.1 - 3.9e-05 23.5 0.8 0.00054 19.7 0.5 2.4 1 1 1 2 2 2 1 Autophagy-related protein 13 Miga PF10265.9 ORX91455.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Mitoguardin Tyrosinase PF00264.20 ORX91456.1 - 1.1e-33 117.5 9.7 2.9e-32 112.8 9.7 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase WD40 PF00400.32 ORX91457.1 - 4.3e-36 122.3 15.3 3.4e-08 34.0 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91457.1 - 9.8e-13 48.2 0.1 0.011 16.0 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91457.1 - 4.4e-07 30.0 0.2 0.041 13.8 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORX91457.1 - 0.0023 16.6 0.0 0.095 11.2 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 ORX91457.1 - 0.0069 15.1 0.2 0.049 12.3 0.0 2.4 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ORX91457.1 - 0.0075 15.9 0.0 0.4 10.2 0.0 2.5 2 1 1 3 3 3 2 PQQ-like domain Tyrosinase PF00264.20 ORX91458.1 - 1.5e-32 113.7 13.9 3.9e-32 112.3 9.8 2.4 2 1 0 2 2 2 1 Common central domain of tyrosinase CTP_synth_N PF06418.14 ORX91458.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 CTP synthase N-terminus Nsp1_C PF05064.13 ORX91459.1 - 1.3e-34 118.4 6.7 1.3e-34 118.4 6.7 2.7 1 1 1 2 2 2 1 Nsp1-like C-terminal region LTXXQ PF07813.12 ORX91459.1 - 0.0033 18.1 0.3 0.008 16.9 0.2 1.7 1 1 0 1 1 1 1 LTXXQ motif family protein WXG100 PF06013.12 ORX91459.1 - 0.015 15.5 1.0 0.015 15.5 1.0 3.1 2 1 0 3 3 3 0 Proteins of 100 residues with WXG ISG65-75 PF11727.8 ORX91459.1 - 0.021 14.1 2.6 0.014 14.6 1.4 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF16 PF01519.16 ORX91459.1 - 0.068 13.7 6.9 0.42 11.1 0.3 2.9 1 1 1 3 3 3 0 Protein of unknown function DUF16 SKA2 PF16740.5 ORX91459.1 - 0.074 12.8 4.6 1.7 8.5 0.2 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Med30 PF11315.8 ORX91459.1 - 0.075 13.2 3.3 0.71 10.1 0.0 2.9 3 1 0 3 3 3 0 Mediator complex subunit 30 DUF1664 PF07889.12 ORX91459.1 - 0.16 12.0 7.3 1.4 9.0 0.6 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) RPN5_C PF18098.1 ORX91459.1 - 0.25 11.5 2.1 1.1 9.4 0.2 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Streptin-Immun PF11083.8 ORX91459.1 - 0.26 11.7 4.0 0.29 11.6 1.0 2.5 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein TEX12 PF15219.6 ORX91459.1 - 0.27 11.6 4.0 0.31 11.4 0.3 2.4 2 2 0 2 2 2 0 Testis-expressed 12 CLZ PF16526.5 ORX91459.1 - 0.29 11.5 7.8 0.42 11.0 0.6 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PI_PP_I PF18363.1 ORX91459.1 - 0.42 10.8 5.3 6.1 7.1 0.7 2.5 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF948 PF06103.11 ORX91459.1 - 0.47 10.8 5.8 0.17 12.2 0.7 2.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 ORX91459.1 - 0.47 9.8 8.9 2.5 7.4 1.5 3.0 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 ORX91459.1 - 0.73 10.4 14.7 2.5 8.7 3.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-CpG_bind_C PF12269.8 ORX91459.1 - 1 9.1 3.5 3.1 7.5 0.3 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain MobC PF05713.11 ORX91459.1 - 5.7 7.5 6.8 4.7 7.8 0.1 3.4 4 0 0 4 4 4 0 Bacterial mobilisation protein (MobC) Adaptin_N PF01602.20 ORX91460.1 - 2.4e-135 452.1 14.3 2.9e-135 451.8 14.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORX91460.1 - 5.1e-64 215.2 11.6 2.5e-61 206.4 1.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX91460.1 - 7.5e-18 64.7 1.3 3.4e-05 24.2 0.0 5.8 3 3 3 6 6 6 3 HEAT repeats HEAT PF02985.22 ORX91460.1 - 3.6e-11 42.3 6.2 0.0078 16.4 0.1 7.0 7 0 0 7 7 7 2 HEAT repeat Cnd3 PF12719.7 ORX91460.1 - 3.6e-08 32.9 0.2 0.00017 20.9 0.1 2.9 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 ORX91460.1 - 1e-06 28.5 2.6 0.29 11.3 0.0 5.1 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 ORX91460.1 - 2.7e-05 24.0 0.1 1.1 9.0 0.0 3.8 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 ORX91460.1 - 3.2e-05 23.6 1.8 0.55 9.8 0.0 4.1 3 1 1 4 4 4 2 CLASP N terminal DUF5578 PF17741.1 ORX91460.1 - 0.00017 21.1 5.5 0.0061 16.0 0.6 3.4 2 1 1 3 3 3 1 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 ORX91460.1 - 0.0014 18.8 6.3 0.93 9.7 0.0 4.4 1 1 3 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm_2 PF04826.13 ORX91460.1 - 0.0037 16.7 1.9 0.014 14.9 0.1 2.6 2 0 0 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 ORX91460.1 - 0.0052 17.3 2.3 25 5.5 0.1 5.9 7 0 0 7 7 7 0 HEAT-like repeat Sec7_N PF12783.7 ORX91460.1 - 0.025 14.5 3.5 0.2 11.6 0.5 3.1 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RasGEF_N_2 PF14663.6 ORX91460.1 - 0.035 14.5 3.7 4.8 7.6 0.0 4.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3535 PF12054.8 ORX91460.1 - 0.05 12.8 0.4 2 7.5 0.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3535) DUF3361 PF11841.8 ORX91460.1 - 0.18 11.8 4.3 11 6.0 0.2 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) ParcG PF10274.9 ORX91460.1 - 0.41 10.7 7.9 13 5.8 0.1 4.2 3 1 0 4 4 4 0 Parkin co-regulated protein HEAT_UF PF18817.1 ORX91460.1 - 0.45 10.8 4.2 1.1 9.6 0.1 3.4 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 FANCI_S2 PF14676.6 ORX91460.1 - 0.6 10.4 2.9 2 8.7 0.4 3.0 2 2 1 3 3 3 0 FANCI solenoid 2 Pkinase PF00069.25 ORX91461.1 - 8.8e-74 248.2 0.0 2.2e-73 246.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91461.1 - 3.3e-50 170.8 0.0 7.3e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX91461.1 - 0.0026 16.6 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX91461.1 - 0.015 14.6 0.1 0.05 12.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Med15_fungi PF05397.12 ORX91461.1 - 0.016 15.5 2.1 0.023 15.0 0.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 15 DUF4704 PF15787.5 ORX91461.1 - 0.036 13.3 6.9 0.38 9.9 0.1 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4704) Atx10homo_assoc PF09759.9 ORX91461.1 - 0.29 11.2 6.6 0.44 10.6 0.2 3.9 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain INTS5_N PF14837.6 ORX91461.1 - 1.1 8.8 6.7 0.38 10.3 0.2 2.7 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus ARS2 PF04959.13 ORX91462.1 - 1.3e-25 90.9 0.1 1.3e-25 90.9 0.1 2.7 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 ORX91462.1 - 1.1e-22 80.3 8.7 3.1e-22 78.8 8.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 ORX91462.1 - 7.1e-08 32.1 0.5 1.9e-07 30.8 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 ORX91462.1 - 0.00045 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 ORX91462.1 - 0.014 15.7 1.0 0.42 11.0 0.2 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORX91462.1 - 0.057 13.8 1.5 0.16 12.4 1.5 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ig_3 PF13927.6 ORX91462.1 - 0.32 11.6 1.9 0.61 10.7 0.2 2.2 2 0 0 2 2 2 0 Immunoglobulin domain AMP-binding PF00501.28 ORX91463.1 - 3.9e-92 309.1 0.0 4.9e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX91463.1 - 5.5e-16 59.3 0.1 1.7e-15 57.7 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ORX91463.1 - 0.00067 18.6 0.0 0.0031 16.4 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Porin_3 PF01459.22 ORX91464.1 - 6.7e-68 229.1 3.9 7.5e-68 228.9 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Cyclin PF08613.11 ORX91465.1 - 3.1e-40 138.2 0.0 4.9e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Vps51 PF08700.11 ORX91466.1 - 5.4e-22 77.7 4.3 5.4e-22 77.7 4.3 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 ORX91466.1 - 6.9e-15 55.3 1.0 3e-14 53.3 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 ORX91466.1 - 8.1e-13 47.8 3.9 8.1e-13 47.8 3.9 1.6 2 0 0 2 2 2 1 Dor1-like family Vps54_N PF10475.9 ORX91466.1 - 2.3e-06 27.1 7.5 2.3e-06 27.1 7.5 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 ORX91466.1 - 1.9e-05 24.8 4.4 1.9e-05 24.8 4.4 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 ORX91466.1 - 0.00017 21.8 3.0 0.00017 21.8 3.0 2.9 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 ORX91466.1 - 0.0021 17.9 1.8 0.0021 17.9 1.8 2.2 3 0 0 3 3 2 1 Sec8 exocyst complex component specific domain Vps53_N PF04100.12 ORX91466.1 - 0.0076 15.3 6.6 0.02 13.9 6.6 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal Atg14 PF10186.9 ORX91466.1 - 0.062 12.4 1.8 0.13 11.4 1.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Snapin_Pallidin PF14712.6 ORX91466.1 - 0.12 12.8 4.9 0.18 12.2 2.6 2.6 2 1 0 2 2 1 0 Snapin/Pallidin DUF641 PF04859.12 ORX91466.1 - 0.2 12.0 1.4 0.56 10.6 1.4 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4795 PF16043.5 ORX91466.1 - 0.24 11.0 5.1 0.54 9.8 3.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) LidA_Long_CC PF18641.1 ORX91466.1 - 0.26 11.3 4.4 0.6 10.1 4.4 1.6 1 0 0 1 1 1 0 LidA long coiled-coil domain SASRP1 PF15160.6 ORX91466.1 - 0.32 10.6 1.7 0.76 9.4 1.7 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 TolA_bind_tri PF16331.5 ORX91466.1 - 0.34 11.0 5.7 5.4 7.2 0.1 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 ORX91466.1 - 0.43 10.6 10.6 0.05 13.6 5.7 1.9 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 ORX91466.1 - 1.3 7.6 9.2 0.15 10.7 4.5 1.7 2 0 0 2 2 2 0 AAA domain Occludin_ELL PF07303.13 ORX91466.1 - 2.4 8.9 5.0 1.4 9.7 0.9 2.7 3 0 0 3 3 2 0 Occludin homology domain ATG16 PF08614.11 ORX91466.1 - 3.2 7.9 9.2 0.22 11.7 3.5 1.9 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 ORX91466.1 - 4.2 8.1 7.3 61 4.3 7.3 2.7 1 1 0 1 1 1 0 Initiation control protein YabA CHAP PF05257.16 ORX91473.1 - 3.6e-10 40.3 3.6 3.6e-10 40.3 3.6 1.7 1 1 1 2 2 2 1 CHAP domain CHAP PF05257.16 ORX91474.1 - 2e-10 41.1 0.5 3.4e-10 40.3 0.5 1.3 1 0 0 1 1 1 1 CHAP domain WD40 PF00400.32 ORX91477.1 - 5.1e-25 87.3 13.8 4.7e-07 30.4 0.6 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91477.1 - 3.2e-15 56.2 0.0 2.1e-06 28.0 0.0 4.9 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91477.1 - 1.7e-06 28.0 0.1 0.00029 20.8 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORX91477.1 - 6.7e-06 25.9 1.2 0.36 10.8 0.1 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORX91477.1 - 4.8e-05 22.5 0.4 0.76 8.7 0.0 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 ORX91477.1 - 0.015 14.4 0.1 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region DUF2251 PF10008.9 ORX91477.1 - 0.17 12.0 0.4 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) U-box PF04564.15 ORX91478.1 - 7e-23 80.6 0.0 1.4e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 ORX91478.1 - 6.2e-16 57.2 2.9 1.7e-05 24.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORX91478.1 - 1.1e-15 56.6 3.4 2.5e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 ORX91478.1 - 4.3e-14 53.0 11.5 4.3e-14 53.0 11.5 2.1 2 0 0 2 2 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 ORX91478.1 - 7.6e-10 38.3 7.4 4e-08 32.8 0.8 3.2 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 ORX91478.1 - 3.2e-06 26.9 13.5 0.22 11.8 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX91478.1 - 5.4e-06 26.4 1.6 0.35 11.3 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX91478.1 - 5.6e-06 26.6 3.5 0.028 14.7 0.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX91478.1 - 1.1e-05 25.6 2.0 0.00058 20.0 0.2 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORX91478.1 - 1.9e-05 25.2 0.0 0.0049 17.5 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX91478.1 - 9e-05 23.0 0.0 1.1 10.3 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX91478.1 - 0.0001 22.1 2.6 1.8 8.8 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORX91478.1 - 0.0018 18.1 1.5 2.6 8.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX91478.1 - 0.013 16.0 0.8 11 6.7 0.0 3.1 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 ORX91478.1 - 0.019 14.7 1.2 0.024 14.4 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain zf-NOSIP PF15906.5 ORX91478.1 - 0.026 14.6 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein SHNi-TPR PF10516.9 ORX91478.1 - 0.085 12.3 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR Csm1 PF12539.8 ORX91478.1 - 0.095 13.3 0.4 0.32 11.6 0.3 2.0 1 1 1 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 KilA-N PF04383.13 ORX91479.1 - 0.084 12.7 0.0 0.61 9.9 0.0 2.2 1 1 0 1 1 1 0 KilA-N domain zf-RING_11 PF17123.5 ORX91479.1 - 0.17 11.7 1.5 0.73 9.6 0.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger TPR_2 PF07719.17 ORX91480.1 - 2.1e-07 30.5 3.9 0.038 14.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX91480.1 - 4.1e-07 29.5 3.2 0.0053 16.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX91480.1 - 9.1e-07 29.4 0.2 3.9e-06 27.4 0.1 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX91480.1 - 2.2e-05 24.7 6.7 0.0024 18.1 0.8 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX91480.1 - 4.1e-05 24.0 1.2 0.00012 22.5 1.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX91480.1 - 0.00017 22.1 0.2 0.086 13.7 0.0 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORX91480.1 - 0.00096 19.4 1.8 0.087 13.2 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX91480.1 - 0.0011 18.6 5.3 0.0038 16.9 0.8 2.9 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 ORX91480.1 - 0.0023 18.0 4.4 0.69 10.3 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF2379 PF09543.10 ORX91480.1 - 0.011 16.0 2.0 2.2 8.5 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2379) TPR_6 PF13174.6 ORX91480.1 - 0.018 15.6 3.3 8.7 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PGA_cap PF09587.10 ORX91480.1 - 0.027 13.9 0.1 0.056 12.9 0.1 1.4 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF4363 PF14276.6 ORX91480.1 - 0.038 14.1 1.3 0.69 10.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) FapA PF03961.13 ORX91480.1 - 0.051 12.2 1.1 0.062 11.9 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A T3SSipB PF16535.5 ORX91480.1 - 0.055 13.9 4.9 0.12 12.9 3.3 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB TPR_9 PF13371.6 ORX91480.1 - 0.11 12.7 0.1 1.1 9.5 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX91480.1 - 0.12 12.5 0.3 0.77 9.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX91480.1 - 0.33 10.9 3.9 0.34 10.9 0.6 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HATPase_c PF02518.26 ORX91481.1 - 3.3e-51 172.5 2.3 2.1e-25 89.4 0.4 3.4 4 0 0 4 4 4 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX91481.1 - 5e-47 158.7 0.2 1e-21 77.2 0.0 3.6 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 ORX91481.1 - 2.3e-26 91.6 3.4 2e-13 50.2 0.1 2.8 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain GAF PF01590.26 ORX91481.1 - 4e-07 30.7 0.0 2.9e-05 24.7 0.0 3.0 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 ORX91481.1 - 3.6e-06 26.9 0.0 0.03 14.1 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 ORX91481.1 - 1.2e-05 25.6 0.0 0.049 13.9 0.0 2.7 2 0 0 2 2 2 2 GAF domain PAS_4 PF08448.10 ORX91481.1 - 4.2e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORX91481.1 - 0.00097 19.4 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain SSF PF00474.17 ORX91482.1 - 2.5e-09 36.5 28.9 5.3e-08 32.1 28.9 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family LD_cluster2 PF18163.1 ORX91482.1 - 0.25 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster2 RGS PF00615.19 ORX91483.1 - 2.2e-13 50.5 0.1 2.7e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORX91483.1 - 0.029 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF3387 PF11867.8 ORX91483.1 - 0.051 12.9 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Ras PF00071.22 ORX91485.1 - 3.1e-09 36.6 0.0 0.0002 21.0 0.0 2.4 1 1 1 2 2 2 2 Ras family Isy1 PF06246.12 ORX91486.1 - 2.6e-08 33.8 1.1 2.9e-08 33.6 1.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family EXS PF03124.14 ORX91487.1 - 3.8e-61 207.2 5.1 4.3e-61 207.1 5.1 1.0 1 0 0 1 1 1 1 EXS family DEAD PF00270.29 ORX91488.1 - 7.5e-48 162.6 0.0 1.2e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX91488.1 - 3.7e-32 111.0 0.0 1.5e-31 109.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX91488.1 - 0.00061 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORX91488.1 - 0.03 13.1 0.0 0.078 11.7 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 ORX91488.1 - 0.039 14.2 0.1 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 ORX91488.1 - 0.075 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase BAR_2 PF10455.9 ORX91489.1 - 6.8e-47 160.0 1.9 1.2e-45 155.8 1.9 2.0 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORX91489.1 - 3.1e-17 63.0 1.0 7.4e-17 61.8 1.0 1.6 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORX91489.1 - 6.4e-06 26.0 0.3 6.4e-06 26.0 0.3 1.9 2 1 0 2 2 2 1 BAR domain of APPL family LytTR PF04397.15 ORX91489.1 - 0.083 13.1 0.3 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 LytTr DNA-binding domain CLP_protease PF00574.23 ORX91490.1 - 8.3e-85 283.3 0.0 9.9e-85 283.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 ORX91490.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase zf-H2C2_2 PF13465.6 ORX91491.1 - 3.1e-09 36.9 16.7 2.7e-06 27.5 4.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX91491.1 - 1e-08 35.1 12.9 9.4e-05 22.7 3.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX91491.1 - 4.8e-05 23.8 9.8 0.031 15.1 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX91491.1 - 0.016 15.2 8.6 1.4 9.0 0.3 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ORX91491.1 - 0.033 14.6 2.3 0.089 13.2 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX91491.1 - 0.068 13.5 0.9 0.18 12.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CsbD PF05532.12 ORX91492.1 - 0.0046 16.8 0.1 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 CsbD-like DUF3759 PF12585.8 ORX91493.1 - 0.063 13.3 29.7 10 6.2 0.3 7.5 7 0 0 7 7 7 0 Protein of unknown function (DUF3759) DUF4722 PF15849.5 ORX91493.1 - 0.12 12.1 0.6 12 5.6 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) PWI PF01480.17 ORX91495.1 - 0.002 18.4 0.2 0.02 15.2 0.2 2.1 2 0 0 2 2 2 1 PWI domain NAP PF00956.18 ORX91496.1 - 0.00012 21.4 1.3 0.00047 19.4 1.4 1.7 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) DUF5082 PF16888.5 ORX91496.1 - 0.019 15.3 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Phage_Mu_Gam PF07352.12 ORX91496.1 - 0.052 13.4 0.2 0.058 13.3 0.2 1.0 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein kleA_kleC PF17383.2 ORX91496.1 - 0.12 12.7 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Rad51 PF08423.11 ORX91497.1 - 1.1e-06 28.2 0.0 1.6e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Rad51 AAA_22 PF13401.6 ORX91497.1 - 0.064 13.5 0.0 1.2 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 ORX91497.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mito_carr PF00153.27 ORX91498.1 - 5.1e-59 196.2 0.1 1e-18 67.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 ORX91498.1 - 0.63 10.2 2.7 1 9.5 0.8 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Ribosomal_L15e PF00827.17 ORX91499.1 - 1.4e-90 302.1 9.7 1.7e-90 301.9 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP12 PF07542.11 ORX91500.1 - 3.8e-42 143.4 0.2 6.8e-42 142.6 0.2 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein DUF2577 PF10844.8 ORX91500.1 - 0.0072 16.5 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2577) SNARE PF05739.19 ORX91501.1 - 0.36 10.9 1.7 0.45 10.5 0.2 2.0 2 0 0 2 2 2 0 SNARE domain KxDL PF10241.9 ORX91501.1 - 0.66 10.3 8.3 1.6 9.1 0.7 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF4407 PF14362.6 ORX91501.1 - 0.68 9.2 10.1 1.8 7.8 10.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC-like PF12805.7 ORX91501.1 - 2.8 7.0 4.4 0.54 9.3 0.4 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS TPR_2 PF07719.17 ORX91502.1 - 1.7e-11 43.3 5.7 3.2e-06 26.8 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat LRR_4 PF12799.7 ORX91502.1 - 2.7e-11 43.5 21.0 5.6e-05 23.4 0.2 7.0 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX91502.1 - 1.4e-10 40.8 8.5 0.003 17.3 0.2 5.0 4 1 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 ORX91502.1 - 1.3e-09 37.3 27.0 0.031 14.3 0.3 9.0 9 0 0 9 9 9 4 Leucine Rich repeat F-box-like PF12937.7 ORX91502.1 - 4.9e-09 35.9 3.5 1.2e-08 34.8 3.5 1.7 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.28 ORX91502.1 - 4.3e-08 32.6 5.3 6.5e-06 25.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat F-box PF00646.33 ORX91502.1 - 1e-07 31.6 3.3 1.2e-07 31.4 1.4 2.2 2 0 0 2 2 1 1 F-box domain TPR_11 PF13414.6 ORX91502.1 - 1.6e-07 30.8 1.8 1.6e-05 24.5 0.1 3.0 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 ORX91502.1 - 3.3e-05 24.3 0.3 0.89 10.5 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX91502.1 - 7.3e-05 22.7 4.5 0.012 15.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_1 PF00560.33 ORX91502.1 - 0.00015 21.8 18.8 3.4 8.6 0.7 7.5 7 1 0 7 7 7 2 Leucine Rich Repeat TPR_9 PF13371.6 ORX91502.1 - 0.00049 20.2 0.0 0.0096 16.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 ORX91502.1 - 0.0017 17.3 0.2 0.0058 15.6 0.2 1.8 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 ORX91502.1 - 0.002 18.6 0.2 0.45 11.1 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX91502.1 - 0.053 13.8 2.8 0.62 10.4 0.1 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX91502.1 - 0.075 13.1 2.3 14 6.0 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 ORX91502.1 - 0.13 12.3 6.2 1.8 8.7 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 ORX91502.1 - 0.15 12.1 1.4 19 5.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORX91502.1 - 0.16 12.6 1.3 0.93 10.2 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Dzip-like_N PF13815.6 ORX91502.1 - 0.16 11.9 0.3 0.48 10.4 0.1 1.9 2 0 0 2 2 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal ANAPC3 PF12895.7 ORX91502.1 - 0.19 12.0 1.1 12 6.2 0.2 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 E1_DerP2_DerF2 PF02221.15 ORX91503.1 - 1.6e-24 86.8 0.0 1.9e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 ORX91503.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PPP4R2 PF09184.11 ORX91504.1 - 7.9e-16 58.5 8.7 1.3e-15 57.8 8.7 1.5 1 1 0 1 1 1 1 PPP4R2 PSP1 PF04468.12 ORX91505.1 - 4.7e-33 113.3 1.7 4.7e-33 113.3 1.7 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Ribosomal_L3 PF00297.22 ORX91506.1 - 1.7e-188 626.2 10.6 1.9e-188 626.0 10.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 zf-C2H2 PF00096.26 ORX91507.1 - 0.003 17.9 2.2 0.0064 16.9 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORX91507.1 - 0.07 13.8 0.6 0.27 11.9 0.3 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORX91507.1 - 0.071 14.0 5.0 0.28 12.1 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORX91507.1 - 0.1 12.7 0.4 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger CPDase PF07823.11 ORX91508.1 - 0.0094 15.7 0.3 0.012 15.3 0.3 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein MGC-24 PF05283.11 ORX91508.1 - 0.024 15.1 10.5 0.031 14.7 10.5 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SWI-SNF_Ssr4 PF08549.10 ORX91508.1 - 0.068 11.8 0.4 0.07 11.8 0.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Taxilin PF09728.9 ORX91509.1 - 6.1e-69 232.5 45.9 6.1e-69 232.5 45.9 1.4 1 1 0 1 1 1 1 Myosin-like coiled-coil protein BRE1 PF08647.11 ORX91509.1 - 0.0016 18.5 1.1 0.0016 18.5 1.1 3.5 1 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase DUF4201 PF13870.6 ORX91509.1 - 0.0033 17.2 7.0 0.0033 17.2 7.0 4.3 2 1 2 4 4 4 2 Domain of unknown function (DUF4201) LtuB PF17455.2 ORX91509.1 - 0.045 14.4 6.0 1 10.0 0.2 3.8 3 1 0 3 3 3 0 Late transcription unit B NPV_P10 PF05531.12 ORX91509.1 - 0.41 11.1 0.1 0.41 11.1 0.1 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 ORX91509.1 - 0.55 8.3 34.8 0.16 10.1 5.7 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Virulence_fact PF13769.6 ORX91509.1 - 0.84 9.9 7.7 3.5 7.9 0.9 3.2 2 1 1 3 3 3 0 Virulence factor UPF0242 PF06785.11 ORX91509.1 - 1.8 8.6 44.0 0.38 10.8 23.6 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus THOC7 PF05615.13 ORX91509.1 - 2.8 8.2 35.3 1.5 9.1 5.0 3.3 1 1 2 3 3 3 0 Tho complex subunit 7 GST_N_3 PF13417.6 ORX91515.1 - 2.3e-14 53.6 0.0 4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORX91515.1 - 2.1e-12 47.2 0.0 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX91515.1 - 2.5e-10 40.5 0.0 6.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX91515.1 - 2e-06 27.7 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX91515.1 - 2.1e-06 27.8 0.1 1.6e-05 25.0 0.0 2.3 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX91515.1 - 3.1e-05 24.1 0.1 9.2e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORX91515.1 - 0.0038 17.9 0.0 0.014 16.2 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain Complex1_LYR PF05347.15 ORX91517.1 - 1.7e-15 56.8 0.1 2.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORX91517.1 - 7.8e-05 23.4 0.6 9.3e-05 23.1 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF2015 PF09435.10 ORX91518.1 - 5e-28 97.2 0.0 6.2e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) CUE PF02845.16 ORX91518.1 - 0.049 13.4 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 CUE domain Ribosomal_S17_N PF16205.5 ORX91519.1 - 1.2e-33 115.3 0.4 2.6e-33 114.2 0.4 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORX91519.1 - 2.3e-27 94.9 0.4 3.6e-27 94.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 dsDNA_bind PF01984.20 ORX91520.1 - 9e-35 119.3 8.4 1e-34 119.1 8.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3616 PF12275.8 ORX91520.1 - 0.016 14.7 0.6 0.021 14.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) YjbH PF06082.11 ORX91520.1 - 0.028 13.3 0.1 0.028 13.3 0.1 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH TPR_20 PF14561.6 ORX91520.1 - 0.084 13.2 2.0 0.12 12.7 2.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Malate_DH PF12434.8 ORX91520.1 - 0.71 9.9 0.1 0.71 9.9 0.1 2.4 3 0 0 3 3 3 0 Malate dehydrogenase enzyme peroxidase PF00141.23 ORX91521.1 - 4.8e-49 167.1 0.0 7.1e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Glyco_hydro_18 PF00704.28 ORX91522.1 - 7.9e-16 58.7 2.0 9.5e-16 58.4 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PP2C PF00481.21 ORX91523.1 - 1.5e-43 149.3 0.0 1.9e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORX91523.1 - 6.7e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORX91523.1 - 0.00073 19.5 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 ORX91524.1 - 4.7e-77 258.9 0.0 7.1e-77 258.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91524.1 - 1.1e-44 152.7 0.0 1.7e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORX91524.1 - 1.3e-14 53.6 0.2 2.5e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORX91524.1 - 8.3e-09 35.2 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX91524.1 - 5.5e-06 25.9 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX91524.1 - 1.1e-05 25.1 0.1 2.5e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORX91524.1 - 2.3e-05 23.5 0.4 5e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX91524.1 - 0.0012 18.8 0.0 0.031 14.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX91524.1 - 8.8 5.0 8.0 0.21 10.3 0.7 2.1 2 1 0 2 2 2 0 Fungal protein kinase Inhibitor_I9 PF05922.16 ORX91527.1 - 1.6e-06 28.7 0.0 1.8e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sugar_tr PF00083.24 ORX91528.1 - 1.4e-94 317.6 25.2 1.8e-94 317.2 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX91528.1 - 1.4e-27 96.5 26.0 1.4e-27 96.5 26.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 ORX91528.1 - 4.8e-06 25.7 0.5 4.8e-06 25.7 0.5 2.3 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Folate_carrier PF01770.18 ORX91528.1 - 1.8e-05 23.6 1.9 2e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 Reduced folate carrier TRI12 PF06609.13 ORX91528.1 - 2.3e-05 23.0 13.0 0.00025 19.6 4.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Pro_CA PF00484.19 ORX91529.1 - 9.8e-50 168.9 0.4 1.2e-49 168.6 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Chitin_synth_1 PF01644.17 ORX91530.1 - 6.4e-72 240.9 0.5 9.4e-72 240.3 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORX91530.1 - 3.1e-29 100.7 0.8 5.1e-29 100.0 0.2 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORX91530.1 - 1.1e-26 93.5 2.7 1.1e-21 77.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX91530.1 - 1.2e-07 31.9 0.5 1.2e-07 31.9 0.5 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX91530.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 BTB PF00651.31 ORX91531.1 - 5.1e-12 46.0 0.0 1.7e-11 44.4 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 ORX91531.1 - 0.00019 21.5 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 MATH domain RhoGEF PF00621.20 ORX91532.1 - 3.7e-37 128.3 0.6 3.7e-37 128.3 0.6 2.4 3 0 0 3 3 3 1 RhoGEF domain BAR PF03114.18 ORX91532.1 - 9.7e-23 81.1 7.4 2.5e-22 79.7 7.4 1.7 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORX91532.1 - 1.5e-06 27.7 0.0 3.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX91532.1 - 8.3e-06 25.6 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Di19_C PF14571.6 ORX91532.1 - 0.092 13.3 3.8 0.51 10.9 0.0 2.9 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal SH3_2 PF07653.17 ORX91532.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain PAS_3 PF08447.12 ORX91533.1 - 1.1e-15 57.7 0.0 3.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORX91533.1 - 2.1e-09 37.4 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORX91533.1 - 6.6e-07 29.5 0.0 0.0026 18.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORX91533.1 - 4.4e-06 26.9 0.0 0.05 13.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 ORX91533.1 - 1.9e-05 24.7 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 ORX91533.1 - 0.035 14.1 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 PAS domain PAS_2 PF08446.11 ORX91533.1 - 0.075 13.7 0.0 12 6.7 0.0 2.3 2 0 0 2 2 2 0 PAS fold Stc1 PF12898.7 ORX91534.1 - 8.2e-14 51.9 21.9 1.1e-13 51.6 21.9 1.1 1 0 0 1 1 1 1 Stc1 domain DUF3330 PF11809.8 ORX91534.1 - 0.03 14.4 1.8 0.03 14.4 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3330) Recombinase PF07508.13 ORX91534.1 - 0.097 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Recombinase His_Me_b4a2 PF18275.1 ORX91534.1 - 3.5 7.8 14.8 1.1 9.4 2.9 2.9 1 1 1 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain PolC_DP2 PF03833.13 ORX91534.1 - 4.1 5.1 9.3 4.5 5.0 9.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cyclin PF08613.11 ORX91535.1 - 0.0037 17.6 0.6 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX91535.1 - 0.027 14.2 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF3687 PF12459.8 ORX91535.1 - 0.054 13.0 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein SNF2_N PF00176.23 ORX91536.1 - 1e-54 185.6 1.5 1.6e-54 184.9 1.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX91536.1 - 5.1e-20 71.9 0.0 1.8e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORX91536.1 - 4.8e-14 52.2 0.1 1.1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORX91536.1 - 1.7e-09 37.9 0.0 4.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX91536.1 - 0.045 14.1 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.21 ORX91537.1 - 7.8e-118 394.5 18.0 4.5e-63 213.8 1.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family TNFR_16_TM PF18422.1 ORX91537.1 - 4 7.5 8.3 1.9 8.5 0.2 3.8 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Tmemb_14 PF03647.13 ORX91538.1 - 1.5e-25 89.7 3.1 1.8e-25 89.5 3.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C MerC PF03203.14 ORX91538.1 - 0.025 15.0 0.5 0.12 12.9 0.5 1.9 1 1 0 1 1 1 0 MerC mercury resistance protein Aim19 PF10315.9 ORX91538.1 - 0.097 13.0 0.6 0.25 11.6 0.6 1.9 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 MMS19_C PF12460.8 ORX91539.1 - 7.3e-99 331.7 15.4 7.3e-99 331.7 15.4 5.0 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 ORX91539.1 - 3.9e-93 311.8 9.3 6.8e-92 307.7 0.5 5.3 4 1 3 7 7 7 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 ORX91539.1 - 0.00015 22.2 3.5 1.6 9.4 0.2 4.9 3 1 2 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 ORX91539.1 - 0.00091 19.6 0.6 0.25 11.7 0.0 3.9 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 ORX91539.1 - 0.0089 16.2 6.4 1.1 9.7 0.1 4.5 3 0 0 3 3 3 2 HEAT repeat RTP1_C1 PF10363.9 ORX91539.1 - 0.03 14.5 0.4 1.1 9.4 0.2 3.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4149 PF13664.6 ORX91539.1 - 0.098 13.0 0.3 0.76 10.1 0.3 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) RICTOR_M PF14666.6 ORX91539.1 - 0.22 11.3 2.0 2.8 7.8 0.0 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Ipi1_N PF12333.8 ORX91539.1 - 0.42 11.2 5.0 8 7.1 0.4 4.2 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Peptidase_M36 PF02128.15 ORX91540.1 - 9.9e-160 531.7 3.5 1.3e-159 531.3 3.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 ORX91540.1 - 9.7e-15 54.1 2.7 2e-14 53.2 2.7 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 ORX91540.1 - 0.00042 20.2 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain DNA_binding_1 PF01035.20 ORX91541.1 - 3.4e-20 72.0 0.0 1e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HORMA PF02301.18 ORX91542.1 - 2e-28 99.4 0.6 2.4e-28 99.2 0.6 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 ORX91542.1 - 0.00016 21.7 0.2 0.0021 18.1 0.2 2.4 1 1 0 1 1 1 1 Autophagy-related protein 101 Disaggr_assoc PF08480.10 ORX91542.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Disaggregatase related bacHORMA_2 PF18173.1 ORX91542.1 - 0.14 12.0 0.5 0.43 10.4 0.1 2.0 1 1 1 2 2 2 0 Bacterial HORMA domain 2 zf-C2H2 PF00096.26 ORX91543.1 - 3.1e-13 49.4 9.7 3.6e-06 27.1 4.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX91543.1 - 8.1e-11 41.8 11.6 1.7e-08 34.5 1.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX91543.1 - 2.2e-10 40.5 7.9 1.5e-05 25.4 2.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX91543.1 - 0.0001 22.2 7.5 0.0045 16.9 2.1 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORX91543.1 - 0.00065 19.5 3.9 0.021 14.7 0.1 2.4 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX91543.1 - 0.01 15.6 11.9 0.46 10.3 6.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 ORX91543.1 - 0.013 15.8 2.3 0.1 12.9 2.3 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX91543.1 - 0.026 14.3 6.4 0.071 12.9 0.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Ogr_Delta PF04606.12 ORX91543.1 - 0.028 14.4 0.9 3.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 ORX91543.1 - 0.028 14.7 1.2 0.37 11.1 0.2 2.4 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX91543.1 - 0.072 13.5 5.4 0.35 11.3 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORX91543.1 - 0.19 11.4 2.9 0.65 9.7 1.1 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 ORX91543.1 - 0.35 10.7 3.0 0.15 11.9 0.7 1.6 2 0 0 2 2 2 0 GAGA factor Rab5ip PF07019.12 ORX91544.1 - 1.5e-22 80.0 9.4 1.8e-22 79.7 9.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) adh_short PF00106.25 ORX91545.1 - 3.3e-37 127.9 0.1 1.1e-35 122.9 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX91545.1 - 3.4e-24 85.7 0.0 5.1e-23 81.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX91545.1 - 4.7e-12 46.2 0.0 7.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX91545.1 - 8.6e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX91545.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORX91545.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORX91545.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Nro1 PF12753.7 ORX91546.1 - 4.1e-15 55.7 20.4 1.8e-10 40.4 8.4 2.7 1 1 2 3 3 3 2 Nuclear pore complex subunit Nro1 DUF357 PF04010.13 ORX91546.1 - 0.0043 17.1 1.1 0.032 14.3 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF357) SMBP PF16785.5 ORX91546.1 - 0.085 13.1 6.3 9.5 6.5 0.2 3.7 4 1 0 4 4 4 0 Small metal-binding protein Vta1 PF04652.16 ORX91546.1 - 0.87 9.5 7.5 0.3 11.1 3.9 2.1 2 0 0 2 2 2 0 Vta1 like TPR_16 PF13432.6 ORX91546.1 - 1.1 9.9 5.4 22 5.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat USP8_dimer PF08969.11 ORX91546.1 - 2 8.6 10.8 0.85 9.8 0.1 3.6 2 2 2 4 4 4 0 USP8 dimerisation domain TPR_8 PF13181.6 ORX91546.1 - 2.8 8.4 7.1 15 6.1 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat ATP-synt_ab PF00006.25 ORX91547.1 - 1.3e-74 250.5 0.0 3.4e-74 249.1 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORX91547.1 - 1.9e-49 167.2 0.3 3.4e-49 166.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORX91547.1 - 5e-20 71.8 1.9 1.5e-19 70.3 1.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ORX91547.1 - 0.053 13.7 1.9 0.85 9.8 1.9 2.5 1 1 0 1 1 1 0 HAS barrel domain ATPase_2 PF01637.18 ORX91547.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mt_ATP-synt_B PF05405.14 ORX91548.1 - 3.8e-49 166.5 9.2 4.8e-49 166.1 9.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Yuri_gagarin PF15934.5 ORX91548.1 - 0.0016 18.3 3.0 0.0019 18.1 3.0 1.1 1 0 0 1 1 1 1 Yuri gagarin DUF2209 PF09974.9 ORX91548.1 - 0.057 13.7 1.5 0.1 12.9 1.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DUF5623 PF18536.1 ORX91548.1 - 0.27 11.6 2.2 0.52 10.6 0.8 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5623) Fib_alpha PF08702.10 ORX91548.1 - 0.43 10.8 7.9 1.3 9.3 7.6 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L37 PF08561.10 ORX91550.1 - 1.4e-19 70.7 3.1 1.1e-17 64.7 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Alg14 PF08660.11 ORX91551.1 - 1e-61 207.9 0.0 1.2e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 ORX91551.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Fringe PF02434.16 ORX91553.1 - 2.4e-09 37.0 0.1 4.3e-08 32.9 0.1 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 ORX91553.1 - 8.6e-08 32.2 0.2 1.4e-06 28.3 0.3 2.1 1 1 1 2 2 2 1 Galactosyltransferase XRN_N PF03159.18 ORX91560.1 - 2.6e-74 249.7 0.1 1.1e-73 247.7 0.1 1.7 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF2533 PF10752.9 ORX91560.1 - 0.053 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) SF3A3 PF16837.5 ORX91560.1 - 0.079 13.5 0.1 0.99 10.0 0.1 2.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 z-alpha PF02295.17 ORX91560.1 - 0.11 12.6 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain DnaJ PF00226.31 ORX91561.1 - 7e-24 83.7 2.2 1.4e-23 82.7 2.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 ORX91561.1 - 0.0059 16.9 1.2 0.0091 16.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) RPT PF13446.6 ORX91561.1 - 0.0075 16.2 0.2 0.019 14.9 0.2 1.7 1 1 0 1 1 1 1 A repeated domain in UCH-protein Gly-zipper_Omp PF13488.6 ORX91561.1 - 0.058 13.4 4.4 0.1 12.6 4.4 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 ORX91561.1 - 0.21 11.9 1.0 0.4 11.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 ORX91561.1 - 1.1 9.0 4.3 1.7 8.5 4.0 1.4 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 ORX91561.1 - 1.3 8.8 6.2 0.62 9.9 1.0 2.0 1 1 0 1 1 1 0 Glycine-zipper domain Cpn60_TCP1 PF00118.24 ORX91562.1 - 1e-172 575.2 3.7 1.2e-172 575.0 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_2 PF03142.15 ORX91563.1 - 3.3e-254 844.4 1.2 4.7e-254 843.9 1.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX91563.1 - 1.7e-12 47.7 0.0 1.1e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX91563.1 - 3.7e-10 40.1 7.0 3.7e-10 40.1 7.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX91563.1 - 0.17 11.4 0.0 21 4.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 FGGY_N PF00370.21 ORX91564.1 - 2e-73 246.9 0.0 2.8e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ORX91564.1 - 6.9e-68 228.3 0.9 1.1e-67 227.7 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain TGT PF01702.18 ORX91565.1 - 4.9e-83 279.2 0.0 5.8e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CcmH PF03918.14 ORX91565.1 - 0.042 13.1 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PK PF00224.21 ORX91566.1 - 2.9e-165 549.3 1.7 3.8e-165 548.9 1.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX91566.1 - 6.8e-36 123.0 0.1 3e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX91566.1 - 0.00018 20.7 1.0 0.00065 18.9 0.1 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Cellulase PF00150.18 ORX91566.1 - 0.091 12.2 0.0 0.82 9.0 0.0 2.2 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.7 ORX91568.1 - 1.6e-16 60.6 2.8 1.6e-08 35.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX91568.1 - 1.7e-12 47.3 0.1 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TIG PF01833.24 ORX91568.1 - 2.4e-11 43.6 0.7 1.2e-10 41.3 0.1 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 ORX91568.1 - 6.7e-10 39.3 0.1 1.9e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORX91568.1 - 1.9e-08 34.4 0.3 0.003 17.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORX91568.1 - 1.2e-05 25.3 0.1 0.0097 16.3 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat CCDC84 PF14968.6 ORX91568.1 - 0.05 13.2 0.2 0.05 13.2 0.2 2.7 3 1 0 3 3 3 0 Coiled coil protein 84 WD40 PF00400.32 ORX91569.1 - 9.6e-14 51.6 14.0 0.00028 21.6 0.8 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91569.1 - 2.1e-08 34.4 0.0 0.11 12.8 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91569.1 - 1.2e-05 25.2 0.2 0.0013 18.6 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX91569.1 - 0.092 11.7 0.1 0.28 10.1 0.0 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 ORX91570.1 - 6.1e-38 130.3 0.3 1.3e-37 129.3 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX91570.1 - 5.5e-27 94.3 0.3 6.2e-26 90.9 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX91570.1 - 1.9e-08 34.5 0.0 3.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORX91570.1 - 0.001 18.4 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 ORX91570.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Mur_ligase_M PF08245.12 ORX91571.1 - 1.1e-07 32.0 0.0 1.9e-05 24.7 0.0 2.8 1 1 0 1 1 1 1 Mur ligase middle domain PK PF00224.21 ORX91572.1 - 9.2e-159 527.9 0.4 1.2e-158 527.6 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX91572.1 - 6.9e-35 119.8 0.0 2.5e-34 118.0 0.0 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX91572.1 - 0.00013 21.2 0.4 0.00031 20.0 0.4 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 ORX91572.1 - 0.032 13.2 0.1 0.089 11.8 0.0 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 ORX91572.1 - 0.086 12.3 0.0 8.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) HMA PF00403.26 ORX91573.1 - 4.2e-72 238.5 5.5 5.7e-14 52.3 0.0 5.6 5 0 0 5 5 5 5 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 ORX91573.1 - 2.8e-47 160.6 0.4 1.3e-46 158.4 0.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORX91573.1 - 8.5e-45 153.6 0.1 1.3e-44 153.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX91573.1 - 0.0003 20.6 2.7 0.0009 19.0 1.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Oxidored_q2 PF00420.24 ORX91573.1 - 0.023 14.3 0.2 0.076 12.7 0.2 1.9 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Fer2_BFD PF04324.15 ORX91573.1 - 0.036 14.4 12.0 15 6.0 0.1 6.1 6 0 0 6 6 6 0 BFD-like [2Fe-2S] binding domain DUF2997 PF11211.8 ORX91573.1 - 0.089 12.6 2.1 1.2e+02 2.5 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2997) GFA PF04828.14 ORX91573.1 - 0.11 12.9 0.4 25 5.3 0.0 3.9 4 1 1 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme CitMHS PF03600.16 ORX91578.1 - 4.1e-16 59.1 5.2 6.7e-16 58.3 5.1 1.5 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 ORX91578.1 - 0.0034 16.8 4.0 0.0034 16.8 4.0 2.2 2 0 0 2 2 2 1 Arsenical pump membrane protein DUF3267 PF11667.8 ORX91578.1 - 1 9.7 13.3 0.47 10.8 2.1 3.4 3 0 0 3 3 3 0 Putative zincin peptidase G-alpha PF00503.20 ORX91579.1 - 2.9e-121 404.9 1.7 3.4e-121 404.7 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX91579.1 - 1.1e-15 57.5 0.9 3.2e-11 43.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX91579.1 - 7.2e-06 25.5 3.3 0.00011 21.6 0.0 2.7 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 ORX91579.1 - 0.019 14.7 0.1 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger Roc PF08477.13 ORX91579.1 - 0.027 14.7 0.2 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORX91579.1 - 0.028 14.7 0.1 0.08 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORX91579.1 - 0.071 12.6 0.1 1.7 8.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ORX91579.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORX91579.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family B12D PF06522.11 ORX91581.1 - 0.00042 20.0 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GATA PF00320.27 ORX91582.1 - 1.7e-14 53.1 7.6 3.2e-14 52.2 7.6 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF3446 PF11928.8 ORX91583.1 - 0.033 14.5 13.8 0.052 13.8 13.8 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain FA_desaturase PF00487.24 ORX91583.1 - 0.11 12.3 0.3 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase SR-25 PF10500.9 ORX91583.1 - 0.48 10.0 14.5 0.62 9.6 14.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Esterase_phd PF10503.9 ORX91600.1 - 4.1e-05 23.2 0.1 7.4e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORX91600.1 - 0.001 18.6 0.2 0.0096 15.4 0.3 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 ORX91600.1 - 0.0011 18.7 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 ORX91600.1 - 0.0058 15.3 0.2 0.3 9.7 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ORX91600.1 - 0.044 13.6 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase YbjN PF10722.9 ORX91601.1 - 0.064 13.3 0.2 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Putative bacterial sensory transduction regulator Cyclin PF08613.11 ORX91602.1 - 4e-12 46.8 0.1 7e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX91602.1 - 6.4e-07 29.2 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chitin_synth_2 PF03142.15 ORX91603.1 - 4.7e-215 715.2 1.1 5.6e-215 714.9 1.1 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX91603.1 - 1.9e-12 47.5 6.0 5.7e-12 46.0 6.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX91603.1 - 1.2e-11 44.9 0.0 5.5e-11 42.8 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX91603.1 - 1.4e-05 25.0 0.0 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX91603.1 - 0.0045 16.5 0.0 0.089 12.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF1657 PF07870.11 ORX91603.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Chs7 PF12271.8 ORX91604.1 - 1.8e-100 336.0 14.5 2.1e-100 335.8 14.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Phage_holin_5_2 PF16079.5 ORX91604.1 - 7.7 6.9 11.7 3.2 8.1 1.2 3.0 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V LSM PF01423.22 ORX91605.1 - 3.7e-20 71.4 0.0 4.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain CLP1_P PF16575.5 ORX91606.1 - 3.5e-54 183.5 0.0 7.8e-54 182.3 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 ORX91606.1 - 4.3e-35 119.8 0.0 6.9e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 ORX91606.1 - 3.1e-32 111.4 0.0 4.9e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 ORX91606.1 - 0.0094 16.0 0.0 0.071 13.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.6 ORX91606.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 ORX91606.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX91606.1 - 0.029 14.8 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 ORX91606.1 - 0.03 14.1 0.0 0.084 12.6 0.0 1.8 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ORX91606.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.7 ORX91606.1 - 0.045 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 ORX91606.1 - 0.087 13.3 0.0 0.55 10.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 ORX91606.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phlebovirus_NSM PF07246.11 ORX91606.1 - 0.2 11.0 0.1 0.35 10.2 0.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MT-A70 PF05063.14 ORX91608.1 - 9.6e-06 25.6 0.4 1.3e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 MT-A70 Chs7 PF12271.8 ORX91609.1 - 2.4e-101 338.9 18.3 2.7e-101 338.7 18.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Col_cuticle_N PF01484.17 ORX91609.1 - 0.37 10.9 3.7 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF2070 PF09843.9 ORX91609.1 - 0.92 7.7 30.7 0.05 11.9 22.7 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) SH3_9 PF14604.6 ORX91610.1 - 1.5e-05 24.7 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX91610.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Oxidored-like PF09791.9 ORX91611.1 - 3e-20 71.6 2.1 4.6e-20 71.0 2.1 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF4515 PF14988.6 ORX91611.1 - 0.03 14.2 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Nop PF01798.18 ORX91612.1 - 1.1e-89 299.9 0.1 1.1e-89 299.9 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORX91612.1 - 2.2e-22 79.2 1.4 2.2e-22 79.2 1.4 3.2 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Uteroglobin PF01099.17 ORX91612.1 - 0.0091 16.3 2.0 0.23 11.8 0.1 3.2 3 0 0 3 3 3 1 Uteroglobin family RR_TM4-6 PF06459.12 ORX91612.1 - 6.8 6.4 16.9 13 5.5 16.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 ORX91612.1 - 6.9 4.8 15.1 11 4.2 15.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Lipase_GDSL PF00657.22 ORX91614.1 - 2.5e-05 24.4 0.0 3.3e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORX91614.1 - 0.069 13.5 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 ORX91614.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 OSK domain GTP_EFTU PF00009.27 ORX91615.1 - 2.8e-53 180.4 0.0 4.6e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORX91615.1 - 1.1e-19 70.2 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORX91615.1 - 1.6e-08 34.8 1.8 3.1e-08 33.9 0.4 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX91615.1 - 6.7e-07 29.4 0.3 1.7e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX91615.1 - 0.00012 21.6 0.2 0.0016 18.0 0.2 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 ORX91615.1 - 0.0029 16.9 0.1 0.0047 16.2 0.1 1.3 1 0 0 1 1 1 1 Septin Arf PF00025.21 ORX91615.1 - 0.013 15.0 0.0 0.033 13.6 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX91615.1 - 0.041 13.8 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase OB_NTP_bind PF07717.16 ORX91616.1 - 6.1e-24 84.2 0.0 2.4e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ORX91616.1 - 2e-15 57.0 0.1 2e-15 57.0 0.1 3.1 3 2 0 3 3 1 1 Helicase associated domain (HA2) AAA_30 PF13604.6 ORX91616.1 - 0.00023 21.0 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORX91616.1 - 0.0022 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORX91616.1 - 0.0033 17.7 0.2 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 ORX91616.1 - 0.0051 17.1 0.0 0.032 14.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PWI PF01480.17 ORX91616.1 - 0.0096 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 PWI domain DEAD PF00270.29 ORX91616.1 - 0.019 14.7 0.2 0.066 13.0 0.1 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 ORX91616.1 - 0.039 13.4 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ORX91616.1 - 0.044 13.1 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 ORX91616.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORX91616.1 - 0.086 12.5 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cullin PF00888.22 ORX91617.1 - 6.9e-202 672.4 17.9 9e-202 672.0 17.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORX91617.1 - 1.6e-23 82.5 1.5 1.6e-23 82.5 1.5 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain SecA_SW PF07516.13 ORX91617.1 - 0.0044 17.1 0.2 0.0044 17.1 0.2 3.3 3 2 1 4 4 4 1 SecA Wing and Scaffold domain NAD_kinase PF01513.21 ORX91618.1 - 5.1e-67 226.1 0.0 7.4e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase CedA PF10729.9 ORX91618.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Cell division activator CedA Glyco_transf_49 PF13896.6 ORX91619.1 - 5.5e-61 206.7 3.3 4.1e-48 164.4 0.9 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 ORX91619.1 - 0.022 15.3 0.2 0.057 13.9 0.2 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 MuF_C PF18819.1 ORX91619.1 - 0.12 12.3 0.4 0.31 11.0 0.4 1.7 1 1 0 1 1 1 0 Phage MuF-C-terminal domain ComX PF05952.12 ORX91619.1 - 0.19 11.7 0.0 0.56 10.2 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX WD40_alt PF14077.6 ORX91620.1 - 0.054 13.4 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif DASH_Spc19 PF08287.11 ORX91620.1 - 0.11 12.3 4.9 0.55 10.1 4.4 2.3 1 1 2 3 3 3 0 Spc19 DUF5413 PF17434.2 ORX91620.1 - 0.12 12.7 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5413) SLATT_5 PF18160.1 ORX91620.1 - 0.13 11.6 0.6 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HR1 PF02185.16 ORX91620.1 - 6.6 6.9 9.2 3.5 7.8 0.6 2.7 3 0 0 3 3 3 0 Hr1 repeat PRK PF00485.18 ORX91621.1 - 9.7e-32 110.3 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 ORX91621.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORX91621.1 - 0.0089 16.4 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORX91621.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 ORX91621.1 - 0.052 14.1 0.1 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 ORX91621.1 - 0.058 12.9 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MeaB PF03308.16 ORX91621.1 - 0.064 12.2 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ORX91621.1 - 0.11 12.2 0.4 0.62 9.8 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 ORX91621.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3472 PF11958.8 ORX91636.1 - 0.0011 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Alpha_E3_glycop PF01563.16 ORX91637.1 - 3 8.0 7.7 20 5.3 0.1 3.4 3 0 0 3 3 3 0 Alphavirus E3 glycoprotein Annexin PF00191.20 ORX91638.1 - 1.6e-80 265.1 0.7 3e-23 81.7 0.0 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 ORX91638.1 - 0.011 16.2 0.3 1 9.9 0.0 2.7 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YpjP PF14005.6 ORX91638.1 - 0.07 13.2 0.0 0.88 9.6 0.0 2.3 2 0 0 2 2 2 0 YpjP-like protein YlbE PF14003.6 ORX91638.1 - 0.29 11.6 1.6 42 4.7 0.0 3.0 3 0 0 3 3 3 0 YlbE-like protein Mg_trans_NIPA PF05653.14 ORX91639.1 - 1.9e-13 50.2 10.8 2.7e-09 36.6 4.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORX91639.1 - 1.3e-06 28.7 23.4 0.00039 20.6 1.7 3.0 2 1 1 3 3 3 2 EamA-like transporter family ATPase_gene1 PF09527.10 ORX91639.1 - 0.01 16.0 3.1 0.01 16.0 3.1 3.2 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter UPF0370 PF13980.6 ORX91639.1 - 0.061 13.4 1.5 0.21 11.6 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) DUF4381 PF14316.6 ORX91639.1 - 0.33 11.2 1.4 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4083 PF13314.6 ORX91639.1 - 1.1 9.2 6.4 22 5.1 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4083) CAAD PF14159.6 ORX91639.1 - 6.4 6.7 7.7 0.79 9.6 1.1 3.0 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Aa_trans PF01490.18 ORX91640.1 - 6.6e-78 262.2 34.9 7.6e-78 262.0 34.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-B_box PF00643.24 ORX91641.1 - 5.4e-09 36.1 5.2 5.4e-09 36.1 5.2 3.3 3 0 0 3 3 3 1 B-box zinc finger MATH PF00917.26 ORX91641.1 - 1.1e-05 25.5 0.8 3.1e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 MATH domain zf-C3HC4_3 PF13920.6 ORX91641.1 - 4.6e-05 23.2 15.1 4.6e-05 23.2 15.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Gag_p24 PF00607.20 ORX91641.1 - 0.00017 21.5 2.1 0.00021 21.2 1.2 1.6 2 0 0 2 2 2 1 gag gene protein p24 (core nucleocapsid protein) zf-RING_2 PF13639.6 ORX91641.1 - 0.00079 19.7 18.8 0.00079 19.7 18.8 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX91641.1 - 0.0044 16.8 17.7 0.0044 16.8 17.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PRESAN PF09687.10 ORX91641.1 - 0.022 15.3 1.8 0.17 12.5 1.8 2.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Dynactin_p22 PF07426.11 ORX91642.1 - 4e-28 98.3 8.3 4e-28 98.3 8.3 1.8 2 1 0 2 2 2 1 Dynactin subunit p22 DUF4806 PF16064.5 ORX91642.1 - 0.048 14.0 4.4 7.2 7.0 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4806) Baculo_PEP_C PF04513.12 ORX91642.1 - 0.064 13.3 7.3 0.62 10.1 2.8 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 ORX91642.1 - 0.069 13.0 4.2 0.43 10.4 0.5 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TRPM_tetra PF16519.5 ORX91642.1 - 0.6 10.3 5.7 24 5.1 0.1 3.5 3 0 0 3 3 3 0 Tetramerisation domain of TRPM Cnn_1N PF07989.11 ORX91642.1 - 1.1 9.5 8.0 0.24 11.6 3.8 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 ORX91642.1 - 1.2 9.8 5.3 13 6.5 0.3 3.9 3 1 1 4 4 4 0 SlyX FlaC_arch PF05377.11 ORX91642.1 - 4.4 7.8 9.5 5.4 7.5 0.4 4.0 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) CRR7 PF12095.8 ORX91642.1 - 6.8 7.2 8.0 3.6 8.1 1.6 2.8 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 SAM_1 PF00536.30 ORX91644.1 - 0.0053 17.2 0.0 0.044 14.2 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Exonuc_VII_L PF02601.15 ORX91644.1 - 0.011 15.3 4.1 0.017 14.7 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.11 ORX91644.1 - 0.49 10.2 5.9 7.8 6.3 0.1 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 HA2 PF04408.23 ORX91645.1 - 1.4e-22 80.0 0.0 1.4e-22 80.0 0.0 3.3 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORX91645.1 - 4.9e-20 71.7 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORX91645.1 - 1.2e-10 41.7 0.0 3.8e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORX91645.1 - 5.8e-07 29.9 0.0 2.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 ORX91645.1 - 9.3e-07 28.8 0.1 3.1e-06 27.1 0.1 2.0 2 1 0 2 2 1 1 DEAD/DEAH box helicase AAA_23 PF13476.6 ORX91645.1 - 0.0004 20.9 23.2 0.084 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORX91645.1 - 0.00078 19.8 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Coilin_N PF15862.5 ORX91645.1 - 0.00097 19.0 16.4 0.0021 17.9 16.4 1.6 1 0 0 1 1 1 1 Coilin N-terminus AAA_30 PF13604.6 ORX91645.1 - 0.008 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain GAGA_bind PF06217.12 ORX91645.1 - 0.012 15.9 15.8 0.018 15.3 15.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family T2SSE PF00437.20 ORX91645.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 ORX91645.1 - 0.016 14.6 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 ORX91645.1 - 0.017 14.6 0.0 0.048 13.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1682 PF07946.14 ORX91645.1 - 1.7 7.8 32.1 2.7 7.1 32.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Endostatin PF06482.11 ORX91645.1 - 2.3 7.6 6.9 3.2 7.1 6.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Afi1 PF07792.12 ORX91645.1 - 6.6 7.2 13.2 12 6.4 13.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RAI16-like PF10257.9 ORX91646.1 - 9.9e-66 222.0 0.8 1.5e-65 221.5 0.8 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein GrpE PF01025.19 ORX91646.1 - 0.13 11.9 2.5 2.5 7.7 1.0 2.3 2 0 0 2 2 2 0 GrpE Mad3_BUB1_I PF08311.12 ORX91646.1 - 0.16 11.9 0.1 9.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 DUF924 PF06041.11 ORX91647.1 - 1.3e-57 194.9 0.1 1.4e-57 194.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) GSHPx PF00255.19 ORX91648.1 - 2.5e-44 149.3 0.3 3.3e-44 148.9 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 ORX91648.1 - 0.00059 19.6 0.1 0.0039 16.9 0.1 1.9 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORX91648.1 - 0.00069 19.5 0.1 0.0022 17.9 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family FERM_F1 PF18379.1 ORX91648.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain HLH PF00010.26 ORX91649.1 - 4.6e-17 61.7 3.0 7.4e-17 61.0 3.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_1 PF00561.20 ORX91650.1 - 1.2e-25 90.6 0.0 2.7e-24 86.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX91650.1 - 3.4e-23 82.2 0.0 5.7e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX91650.1 - 2.7e-14 54.3 0.0 4.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORX91650.1 - 4.2e-05 23.3 0.0 0.00013 21.7 0.0 1.9 2 1 0 2 2 2 1 Putative esterase LIDHydrolase PF10230.9 ORX91650.1 - 5.4e-05 22.9 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 ORX91650.1 - 0.00011 22.0 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 ORX91650.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 ORX91650.1 - 0.0037 16.8 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 ORX91650.1 - 0.0075 16.2 0.0 0.05 13.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ORX91650.1 - 0.0087 15.8 0.0 0.079 12.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 ORX91650.1 - 0.014 14.1 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 Ndr family DUF2048 PF09752.9 ORX91650.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 ORX91650.1 - 0.037 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DSPc PF00782.20 ORX91651.1 - 4.4e-34 117.1 0.0 5.2e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX91651.1 - 0.0039 16.8 0.0 0.0043 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORX91651.1 - 0.036 14.2 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_S3_C PF00189.20 ORX91652.1 - 1e-23 83.6 1.1 3.9e-23 81.8 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORX91652.1 - 1.2e-12 47.5 0.1 2.2e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORX91652.1 - 0.043 14.3 0.0 0.086 13.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 ORX91652.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4449 PF14613.6 ORX91653.1 - 4.8e-07 30.0 0.1 4.8e-07 30.0 0.1 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF4449) Ribosomal_S19e PF01090.19 ORX91653.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S19e Arg_decarbox_C PF17944.1 ORX91653.1 - 0.087 13.4 1.3 0.6 10.7 0.1 3.1 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension DUF4449 PF14613.6 ORX91654.1 - 4.8e-05 23.5 0.1 4.8e-05 23.5 0.1 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) Ribosomal_S19e PF01090.19 ORX91654.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S19e EFhand_Ca_insen PF08726.10 ORX91654.1 - 0.14 12.3 0.0 3.3 7.9 0.0 2.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Arg_decarbox_C PF17944.1 ORX91654.1 - 0.15 12.7 1.3 0.54 10.8 0.1 2.8 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension DUF445 PF04286.12 ORX91654.1 - 0.28 11.0 12.5 0.023 14.5 5.3 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF445) Sigma70_ner PF04546.13 ORX91654.1 - 0.4 10.5 0.1 0.4 10.5 0.1 3.3 3 2 0 3 3 3 0 Sigma-70, non-essential region Aldedh PF00171.22 ORX91655.1 - 6.5e-100 334.8 0.0 8.1e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CHASE8 PF17152.4 ORX91655.1 - 0.071 13.4 0.1 16 5.8 0.0 2.7 2 1 0 2 2 2 0 Periplasmic sensor domain Ribosomal_S9 PF00380.19 ORX91655.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S9/S16 ABC2_membrane PF01061.24 ORX91657.1 - 5.5e-35 120.7 19.8 5.5e-35 120.7 19.8 3.4 4 0 0 4 4 3 1 ABC-2 type transporter ABC_tran PF00005.27 ORX91657.1 - 6.2e-26 91.5 0.0 1.1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX91657.1 - 0.00027 20.2 21.8 0.00027 20.2 21.8 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX91657.1 - 0.00039 20.3 0.1 0.4 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORX91657.1 - 0.003 17.5 0.4 0.0055 16.6 0.4 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORX91657.1 - 0.01 15.6 0.8 0.032 14.0 0.8 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX91657.1 - 0.021 15.2 0.3 0.042 14.2 0.3 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX91657.1 - 0.022 15.0 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORX91657.1 - 0.041 13.6 0.7 2 8.1 0.2 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein Rad17 PF03215.15 ORX91657.1 - 0.043 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ORX91657.1 - 0.096 12.4 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 ORX91657.1 - 0.13 11.7 0.1 5.9 6.2 0.1 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORX91657.1 - 0.14 11.7 0.4 0.32 10.5 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORX91657.1 - 0.17 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ORX91657.1 - 0.22 10.5 1.1 0.43 9.5 1.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORX91657.1 - 0.33 10.7 0.8 0.52 10.0 0.8 1.3 1 0 0 1 1 1 0 AAA domain DUF4436 PF14494.6 ORX91657.1 - 0.46 9.7 1.6 0.68 9.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4436) PDR_CDR PF06422.12 ORX91657.1 - 4.1 7.4 6.9 0.48 10.4 0.3 2.8 3 0 0 3 3 2 0 CDR ABC transporter Laminin_EGF PF00053.24 ORX91657.1 - 7.7 6.7 30.6 0.029 14.5 3.8 3.5 2 1 1 3 3 3 0 Laminin EGF domain Pribosyltran_N PF13793.6 ORX91658.1 - 1.1e-48 163.9 0.5 1.4e-47 160.5 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORX91658.1 - 1.9e-47 161.6 3.0 1.2e-39 136.2 1.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORX91658.1 - 1.8e-15 56.8 2.3 1e-13 51.1 0.7 2.4 2 1 0 2 2 2 2 Phosphoribosyl transferase domain Glyco_transf_21 PF13506.6 ORX91659.1 - 1.4e-43 148.4 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORX91659.1 - 5.7e-23 82.0 0.0 9.1e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX91659.1 - 8.3e-13 48.7 0.8 8.3e-13 48.7 0.8 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX91659.1 - 1.9e-06 27.8 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Phosducin PF02114.16 ORX91659.1 - 0.18 10.7 0.5 4.6 6.1 0.3 2.1 2 0 0 2 2 2 0 Phosducin GPP34 PF05719.11 ORX91660.1 - 1.1e-58 198.6 0.0 1.4e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Exo_endo_phos PF03372.23 ORX91661.1 - 1.1e-11 44.8 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 ORX91661.1 - 2.8e-06 27.9 12.2 0.011 16.6 0.5 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat GMP_synt_C PF00958.22 ORX91663.1 - 1.2e-46 156.7 0.1 2.5e-46 155.6 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ORX91663.1 - 4e-35 121.3 0.0 7.2e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORX91663.1 - 2.7e-09 37.1 0.0 5.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 ORX91663.1 - 2.3e-08 33.4 0.1 1.5e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 ORX91663.1 - 0.0015 18.0 0.0 0.0055 16.2 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORX91663.1 - 0.0023 16.8 0.1 0.0064 15.3 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 ORX91663.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 ORX91663.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Peptidase_M22 PF00814.25 ORX91665.1 - 1.2e-89 300.6 0.0 1.4e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 ORX91665.1 - 0.0014 18.3 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus zf-Tim10_DDP PF02953.15 ORX91666.1 - 5.1e-21 74.1 2.7 6.2e-21 73.8 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cyclin_N PF00134.23 ORX91667.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX91667.1 - 0.0096 16.3 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin LPMO_10 PF03067.15 ORX91668.1 - 0.00017 22.3 0.1 0.0004 21.1 0.1 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX91668.1 - 0.012 15.6 0.3 1 9.3 0.3 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 NAD_binding_2 PF03446.15 ORX91669.1 - 8.1e-15 55.3 0.1 1e-14 55.0 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORX91669.1 - 7.7e-08 32.8 0.6 1e-07 32.4 0.6 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORX91669.1 - 5.4e-06 26.5 0.3 1.1e-05 25.5 0.3 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORX91669.1 - 1e-05 25.0 0.1 1.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ORX91669.1 - 2.3e-05 24.1 0.1 3e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ORX91669.1 - 0.00012 22.1 0.6 0.00029 20.9 0.1 1.7 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 ORX91669.1 - 0.00085 19.2 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX91669.1 - 0.00094 19.4 0.1 0.0013 19.0 0.1 1.2 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ORX91669.1 - 0.0011 19.2 0.1 0.0015 18.8 0.1 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Aconitase PF00330.20 ORX91681.1 - 9.1e-165 549.1 0.0 1.1e-164 548.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX91681.1 - 1.3e-40 138.8 0.0 2.8e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_1_2 PF00155.21 ORX91682.1 - 5.8e-89 298.8 0.0 6.6e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acyl-CoA_dh_1 PF00441.24 ORX91683.1 - 9.8e-39 132.9 0.2 1.4e-38 132.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX91683.1 - 3.4e-22 78.4 0.1 6.7e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORX91683.1 - 5.9e-22 77.6 0.0 1.5e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORX91683.1 - 1.2e-21 77.4 0.0 3.2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX91683.1 - 1.5e-07 31.7 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ORX91684.1 - 1e-41 142.6 0.3 1.4e-41 142.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX91684.1 - 2.5e-22 78.9 0.1 4e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORX91684.1 - 5.3e-14 52.8 0.0 1.4e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX91684.1 - 2.3e-07 31.2 0.0 3.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ORX91685.1 - 1e-41 142.6 0.3 1.4e-41 142.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX91685.1 - 2.5e-22 78.9 0.1 4e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORX91685.1 - 6.7e-14 52.5 0.0 1.8e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX91685.1 - 2.3e-07 31.2 0.0 3.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Usp PF00582.26 ORX91686.1 - 5.9e-25 88.4 0.0 1.3e-24 87.3 0.0 1.5 1 1 0 1 1 1 1 Universal stress protein family Ribosomal_L38e PF01781.18 ORX91687.1 - 1.3e-35 121.3 1.7 1.4e-35 121.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORX91687.1 - 0.066 13.4 0.0 0.076 13.2 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORX91687.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 zf-LYAR PF08790.11 ORX91688.1 - 2.8e-14 52.7 5.6 2.8e-14 52.7 5.6 2.7 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger DM PF00751.18 ORX91688.1 - 0.021 14.7 2.1 0.046 13.6 2.1 1.6 1 0 0 1 1 1 0 DM DNA binding domain zf-TRAF PF02176.18 ORX91688.1 - 0.041 14.6 1.4 0.041 14.6 1.4 1.7 2 0 0 2 2 2 0 TRAF-type zinc finger zf_UBZ PF18439.1 ORX91688.1 - 0.052 13.2 0.9 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Presenilin PF01080.17 ORX91688.1 - 3.2 6.4 5.3 4.2 6.0 5.3 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_M24 PF00557.24 ORX91689.1 - 3.3e-39 134.8 0.0 4.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORX91689.1 - 2.3e-09 37.4 1.0 7.3e-09 35.8 1.0 1.9 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORX91689.1 - 0.0098 16.0 0.3 0.026 14.6 0.3 1.7 1 0 0 1 1 1 1 MYND finger Aa_trans PF01490.18 ORX91690.1 - 1.8e-61 208.1 34.6 2.2e-61 207.8 34.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 ORX91691.1 - 1.1e-62 212.0 33.6 1.3e-62 211.8 33.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L22 PF00237.19 ORX91692.1 - 9.4e-44 147.9 0.1 1.3e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Sel1 PF08238.12 ORX91693.1 - 4.2e-36 122.6 28.0 0.00018 22.1 0.2 10.6 10 0 0 10 10 10 9 Sel1 repeat SERTA PF06031.13 ORX91694.1 - 0.14 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 SERTA motif 2-Hacid_dh_C PF02826.19 ORX91696.1 - 3.5e-55 186.1 0.0 5e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORX91696.1 - 2.5e-17 62.8 0.0 3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 ORX91696.1 - 0.0013 18.9 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 ORX91696.1 - 0.039 14.1 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 ORX91696.1 - 0.1 12.9 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORX91696.1 - 0.17 12.5 0.1 0.41 11.3 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aminotran_1_2 PF00155.21 ORX91697.1 - 8.6e-58 196.2 0.0 1.1e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORX91697.1 - 0.0035 16.4 0.0 0.021 13.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORX91697.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORX91697.1 - 0.045 12.3 0.0 0.1 11.1 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF5363 PF17320.2 ORX91697.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5363) Beta_elim_lyase PF01212.21 ORX91697.1 - 0.21 10.9 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.22 ORX91698.1 - 2e-91 307.0 0.0 2.3e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 ORX91698.1 - 0.13 12.4 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Stirrup Transket_pyr PF02779.24 ORX91699.1 - 8.2e-49 165.7 0.0 1.8e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORX91699.1 - 5.6e-48 162.5 0.0 9.2e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORX91699.1 - 4.8e-39 134.1 0.0 8e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component CAF1 PF04857.20 ORX91701.1 - 2.8e-87 292.9 0.1 3.5e-87 292.5 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 ORX91701.1 - 0.008 15.9 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease F_bP_aldolase PF01116.20 ORX91702.1 - 2.5e-83 279.8 0.0 2.9e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TatD_DNase PF01026.21 ORX91702.1 - 0.18 11.2 0.1 2.3 7.5 0.0 2.3 3 0 0 3 3 3 0 TatD related DNase F_bP_aldolase PF01116.20 ORX91703.1 - 4e-78 262.7 0.0 1.7e-76 257.4 0.0 2.0 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-II F_bP_aldolase PF01116.20 ORX91704.1 - 1.7e-92 309.8 0.0 2e-92 309.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II E1-E2_ATPase PF00122.20 ORX91705.1 - 2.1e-53 180.5 1.6 2.1e-53 180.5 1.6 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX91705.1 - 8e-46 156.0 11.5 8e-46 156.0 11.5 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORX91705.1 - 1.2e-21 77.9 3.2 2.3e-21 77.1 0.8 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX91705.1 - 2.2e-21 75.7 0.2 4.3e-21 74.8 0.2 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX91705.1 - 4.9e-20 71.0 2.3 9.3e-20 70.1 0.2 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX91705.1 - 1.5e-08 34.7 2.2 2.3e-06 27.5 1.9 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX91705.1 - 1.8e-07 31.7 0.0 4.9e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Alginate_lyase PF05426.12 ORX91707.1 - 4.4e-76 256.0 0.0 6.6e-76 255.4 0.0 1.3 1 0 0 1 1 1 1 Alginate lyase LRRNT_2 PF08263.12 ORX91708.1 - 0.0011 19.2 3.8 0.0026 18.0 3.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain SKG6 PF08693.10 ORX91708.1 - 0.0075 15.7 1.6 0.017 14.5 1.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MerC PF03203.14 ORX91708.1 - 0.0093 16.4 0.0 0.032 14.7 0.0 1.9 2 0 0 2 2 2 1 MerC mercury resistance protein TMEM132D_C PF15706.5 ORX91708.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Phage_holin_2_4 PF16082.5 ORX91708.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SpoIIE PF07228.12 ORX91709.1 - 4.1e-12 46.4 0.0 5.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORX91709.1 - 5.4e-05 22.9 0.0 0.00016 21.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ORX91709.1 - 0.00078 19.1 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Skp1_POZ PF03931.15 ORX91710.1 - 8.7e-16 57.8 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 ORX91710.1 - 2.8e-05 24.1 0.0 5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Nt_Gln_amidase PF09764.9 ORX91711.1 - 3.8e-37 127.7 0.1 4.4e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase ANAPC4_WD40 PF12894.7 ORX91712.1 - 8.9e-13 48.4 0.0 0.0031 17.8 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORX91712.1 - 2.3e-12 47.2 0.6 0.00011 22.9 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 ORX91712.1 - 4.2e-06 25.6 0.0 0.0017 17.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 ORX91712.1 - 0.00043 19.9 0.1 2.4 7.9 0.0 3.5 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 ORX91712.1 - 0.0032 17.4 0.0 4.9 7.2 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF2415 PF10313.9 ORX91712.1 - 0.017 15.1 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Tim17 PF02466.19 ORX91715.1 - 1.2e-25 90.0 9.4 1.7e-25 89.6 9.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CBFD_NFYB_HMF PF00808.23 ORX91716.1 - 4.8e-06 26.8 0.2 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2 PF00096.26 ORX91717.1 - 1.6e-10 40.8 7.2 4.2e-06 26.9 2.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX91717.1 - 2.9e-08 33.8 13.9 3.2e-06 27.3 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX91717.1 - 1.3e-07 31.8 7.0 6.7e-05 23.4 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 ORX91717.1 - 0.00037 20.3 4.6 0.0011 18.8 0.9 2.1 1 1 1 2 2 2 1 SprT-like zinc ribbon domain zf-met PF12874.7 ORX91717.1 - 0.00061 20.1 0.7 0.00061 20.1 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX91717.1 - 0.00096 19.1 6.5 0.0018 18.2 1.6 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX91717.1 - 0.008 16.4 0.3 0.018 15.3 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORX91717.1 - 0.0082 15.9 5.0 0.015 15.1 0.6 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 ORX91717.1 - 0.022 14.9 3.5 0.68 10.1 3.8 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF3268 PF11672.8 ORX91717.1 - 0.024 14.9 0.2 0.025 14.9 0.2 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain zf-Di19 PF05605.12 ORX91717.1 - 0.035 14.4 1.4 0.041 14.2 1.4 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-DNA_Pol PF08996.10 ORX91717.1 - 0.055 13.2 0.4 0.055 13.2 0.4 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 ORX91717.1 - 0.13 12.3 2.6 0.49 10.5 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger DUF3395 PF11875.8 ORX91718.1 - 3.1e-41 140.9 2.9 5.5e-40 136.8 2.9 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 ORX91718.1 - 4.8e-13 49.0 1.6 5.1e-13 48.9 0.4 1.7 2 0 0 2 2 2 1 DnaJ domain Porin_3 PF01459.22 ORX91718.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic porin HEAT PF02985.22 ORX91719.1 - 1.1e-12 47.0 0.1 0.13 12.6 0.0 7.2 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 ORX91719.1 - 1.2e-10 41.6 0.1 6.3e-06 26.5 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 ORX91719.1 - 8.6e-07 29.1 4.9 0.0021 18.1 0.7 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORX91719.1 - 0.00068 18.3 4.1 0.1 11.1 0.1 3.1 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 ORX91719.1 - 0.0063 17.0 0.0 1.3 9.6 0.0 4.0 4 0 0 4 4 4 1 HEAT-like repeat Cnd3 PF12719.7 ORX91719.1 - 0.0067 15.7 0.3 0.037 13.2 0.1 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 ORX91719.1 - 0.047 14.0 0.1 8 6.9 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion API5 PF05918.11 ORX91719.1 - 0.16 10.8 0.1 0.28 9.9 0.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tmemb_14 PF03647.13 ORX91720.1 - 4.5e-28 97.8 7.9 5e-28 97.7 7.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C dUTPase PF00692.19 ORX91721.1 - 9e-45 151.5 0.0 1.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase CBFD_NFYB_HMF PF00808.23 ORX91722.1 - 1.1e-20 73.6 1.3 1.8e-20 73.0 1.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX91722.1 - 1.8e-18 67.1 0.6 3.2e-18 66.3 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 ORX91722.1 - 0.0018 18.5 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X GAD-like PF08887.11 ORX91722.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 GAD-like domain DUF4199 PF13858.6 ORX91722.1 - 8.6 6.7 5.8 1.5 9.2 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Cyclin PF08613.11 ORX91723.1 - 3.4e-06 27.5 0.6 3.6e-06 27.4 0.6 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX91723.1 - 4.7e-05 23.1 1.1 5.2e-05 23.0 1.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAS_8 PF13188.7 ORX91723.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 PAS domain Peptidase_S9 PF00326.21 ORX91724.1 - 5.2e-58 196.0 0.1 9.2e-58 195.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORX91724.1 - 0.0038 17.1 1.1 24 5.0 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 ORX91724.1 - 0.017 13.1 0.0 0.026 12.5 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Lactonase PF10282.9 ORX91724.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF3385 PF11865.8 ORX91725.1 - 2.1 8.3 4.7 0.78 9.6 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) S4 PF01479.25 ORX91726.1 - 1.3e-11 44.0 0.0 2.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 ORX91726.1 - 5.7e-10 40.0 3.1 1.2e-09 39.0 3.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Paralemmin PF03285.15 ORX91726.1 - 0.024 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Paralemmin OPA3 PF07047.12 ORX91727.1 - 1.6e-41 141.0 2.1 3.4e-41 139.9 2.1 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF4164 PF13747.6 ORX91727.1 - 0.022 15.1 5.0 0.038 14.3 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF4446 PF14584.6 ORX91727.1 - 0.076 13.0 1.6 0.14 12.1 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4727 PF15856.5 ORX91727.1 - 0.076 12.6 0.7 0.14 11.7 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4727) PAS PF00989.25 ORX91730.1 - 2.3e-10 40.5 0.0 8.9e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX91730.1 - 1.1e-09 38.4 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 ORX91730.1 - 0.00069 19.7 0.0 0.11 12.6 0.0 2.6 2 1 0 2 2 2 2 PAS domain PAS_9 PF13426.7 ORX91730.1 - 0.0015 18.8 0.0 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAP2 PF01569.21 ORX91731.1 - 6.7e-29 100.4 0.8 1.3e-28 99.5 0.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX91731.1 - 0.0055 16.4 0.9 0.0055 16.4 0.9 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF5510 PF17629.2 ORX91731.1 - 0.16 11.9 1.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5510) SPW PF03779.14 ORX91731.1 - 0.53 9.9 3.6 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 SPW repeat PAP2_C PF14360.6 ORX91731.1 - 2.3 8.8 5.4 0.26 11.8 0.4 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal cobW PF02492.19 ORX91732.1 - 8.3e-53 178.6 0.7 1.2e-52 178.1 0.7 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORX91732.1 - 1.3e-12 47.5 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ORX91732.1 - 9.2e-06 25.7 0.6 0.071 13.0 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX91732.1 - 0.0015 18.6 0.1 0.0064 16.6 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORX91732.1 - 0.0016 18.7 0.5 0.011 16.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.27 ORX91732.1 - 0.0025 17.4 1.6 0.3 10.6 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 ORX91732.1 - 0.0028 16.8 0.4 0.0068 15.5 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 ORX91732.1 - 0.0032 17.9 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 ORX91732.1 - 0.0084 16.0 2.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORX91732.1 - 0.0086 16.1 0.2 0.072 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORX91732.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 ORX91732.1 - 0.038 13.7 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 ORX91732.1 - 0.049 13.1 0.9 0.1 12.0 0.1 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.6 ORX91732.1 - 0.054 13.3 0.2 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 ORX91732.1 - 0.074 11.1 0.1 1 7.3 0.0 2.1 2 0 0 2 2 2 0 Origin of replication binding protein AAA_18 PF13238.6 ORX91732.1 - 0.086 13.4 0.5 0.21 12.1 0.5 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORX91732.1 - 0.11 13.0 0.8 0.35 11.4 0.8 2.0 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 ORX91732.1 - 0.11 12.6 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORX91732.1 - 0.14 11.9 0.6 0.5 10.1 0.4 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.21 ORX91732.1 - 0.17 11.3 3.2 11 5.5 1.8 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 ORX91732.1 - 1.3 7.9 3.8 6.3 5.7 0.0 2.8 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 ORX91732.1 - 3.2 8.2 10.9 9 6.7 9.7 2.3 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 ORX91734.1 - 1.3e-23 82.8 20.1 0.00064 20.5 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91734.1 - 1.2e-06 28.7 2.4 0.23 11.8 0.1 3.3 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cactin_mid PF10312.9 ORX91735.1 - 2.9e-64 216.5 6.2 2.9e-64 216.5 6.2 3.2 4 0 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 ORX91735.1 - 4.5e-59 197.8 6.9 8.7e-59 196.9 6.9 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 ORX91735.1 - 0.032 14.6 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CPSase_sm_chain PF00988.22 ORX91736.1 - 1e-47 161.2 0.0 1.8e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORX91736.1 - 3.8e-37 127.9 0.0 2.5e-36 125.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORX91736.1 - 0.06 13.1 0.8 4.6 6.9 0.0 2.3 1 1 1 2 2 2 0 Peptidase C26 HSP70 PF00012.20 ORX91737.1 - 2.2e-87 293.7 16.5 3.4e-87 293.1 12.1 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ORX91737.1 - 0.0014 17.5 0.1 0.0063 15.4 0.1 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Spectrin PF00435.21 ORX91737.1 - 0.075 13.5 4.6 0.68 10.4 0.0 3.3 3 0 0 3 3 3 0 Spectrin repeat REPA_OB_2 PF16900.5 ORX91737.1 - 0.25 11.3 1.8 7.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Replication protein A OB domain Forkhead PF00250.18 ORX91738.1 - 2.2e-30 104.8 0.5 4.9e-30 103.6 0.5 1.6 1 0 0 1 1 1 1 Forkhead domain SAG PF04092.13 ORX91738.1 - 0.05 14.4 1.4 0.11 13.3 1.0 1.8 1 1 0 1 1 1 0 SRS domain R3H-assoc PF13902.6 ORX91742.1 - 1.6e-05 25.3 0.5 3.4e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 ORX91742.1 - 0.0078 16.2 0.4 0.0078 16.2 0.4 2.9 3 1 0 3 3 3 1 R3H domain FGE-sulfatase PF03781.16 ORX91743.1 - 6e-28 98.1 1.6 8.8e-28 97.6 1.6 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_31 PF13847.6 ORX91743.1 - 1.4e-10 41.1 0.0 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORX91743.1 - 1.4e-08 34.7 0.0 3.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX91743.1 - 2.5e-07 31.3 0.0 4e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX91743.1 - 1.8e-06 28.5 0.0 0.00024 21.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX91743.1 - 1.1e-05 26.1 0.0 0.0088 16.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain DREV PF05219.12 ORX91743.1 - 8.7e-05 21.7 0.0 0.083 12.0 0.0 2.3 2 0 0 2 2 2 2 DREV methyltransferase DinB_2 PF12867.7 ORX91743.1 - 0.00019 22.0 0.3 0.0005 20.6 0.3 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_7 PF03492.15 ORX91743.1 - 0.12 11.5 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase DUF4679 PF15728.5 ORX91743.1 - 0.19 10.7 0.2 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4679) zf-C2H2 PF00096.26 ORX91744.1 - 8e-12 44.9 11.4 1.1e-05 25.6 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX91744.1 - 7.3e-11 42.0 13.0 9.6e-08 32.1 0.6 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX91744.1 - 9.4e-10 38.5 9.9 0.00011 22.7 2.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX91744.1 - 3.2e-08 33.4 7.9 9.3e-06 25.5 0.9 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX91744.1 - 6.7e-08 32.7 3.6 0.00017 21.9 0.6 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX91744.1 - 2e-05 24.7 7.2 0.0033 17.7 0.2 2.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORX91744.1 - 0.00037 20.3 0.5 0.00037 20.3 0.5 2.3 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 ORX91744.1 - 0.0073 16.6 2.5 0.13 12.6 0.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX91744.1 - 0.048 13.4 14.5 1 9.2 7.3 3.1 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 ORX91744.1 - 1.7 8.7 7.6 4.7 7.3 1.7 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 ORX91744.1 - 2.1 8.2 10.9 1.5 8.7 2.9 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type DAHP_synth_2 PF01474.16 ORX91745.1 - 4.8e-202 671.3 0.0 5.4e-202 671.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Ribosomal_L18 PF17135.4 ORX91746.1 - 3.8e-96 319.9 3.8 4.2e-96 319.7 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORX91746.1 - 0.011 16.4 0.1 0.022 15.4 0.1 1.7 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NIF PF03031.18 ORX91747.1 - 4.5e-56 188.9 0.1 1.5e-55 187.2 0.1 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORX91747.1 - 0.038 14.4 0.2 0.34 11.3 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase F-box PF00646.33 ORX91748.1 - 3.9e-05 23.4 0.7 9.7e-05 22.1 0.7 1.7 1 0 0 1 1 1 1 F-box domain zf-B_box PF00643.24 ORX91748.1 - 0.023 14.9 9.5 0.035 14.2 1.1 2.5 2 0 0 2 2 2 0 B-box zinc finger LRR_4 PF12799.7 ORX91748.1 - 0.17 12.4 0.0 0.69 10.4 0.0 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Sugar_tr PF00083.24 ORX91754.1 - 5.2e-81 272.8 26.5 1.3e-80 271.5 26.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX91754.1 - 3e-26 92.2 30.9 3e-26 92.2 30.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX91754.1 - 7e-05 21.4 1.8 7e-05 21.4 1.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_8 PF05148.15 ORX91756.1 - 2.2e-77 259.8 0.1 4e-77 259.0 0.1 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ORX91756.1 - 4e-06 27.4 1.0 1.9e-05 25.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORX91756.1 - 3.2e-05 23.5 1.7 0.004 16.7 0.1 3.1 2 1 1 3 3 3 2 Methyltransferase small domain Methyltransf_25 PF13649.6 ORX91756.1 - 8.2e-05 23.2 0.4 0.016 15.9 0.0 3.5 2 1 0 2 2 2 1 Methyltransferase domain Pkinase PF00069.25 ORX91757.1 - 1.2e-71 241.1 0.0 2.2e-71 240.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91757.1 - 1.9e-40 138.8 0.0 5.9e-40 137.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORX91757.1 - 2.7e-16 59.1 2.2 4.6e-16 58.3 0.3 2.1 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 ORX91757.1 - 3.9e-06 26.4 0.0 7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX91757.1 - 0.00034 19.7 0.1 0.00055 19.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX91757.1 - 0.00036 20.0 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX91757.1 - 0.0037 17.2 0.0 0.019 14.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX91757.1 - 0.048 13.2 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Peptidase_M13_N PF05649.13 ORX91758.1 - 1.1e-87 295.3 0.0 1.5e-87 294.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX91758.1 - 1.6e-66 223.9 0.0 2.9e-66 223.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF1409 PF07197.12 ORX91758.1 - 0.16 11.9 0.2 0.98 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Mem_trans PF03547.18 ORX91759.1 - 9.2e-50 169.1 16.8 3.4e-31 108.0 3.4 2.0 2 0 0 2 2 2 2 Membrane transport protein zf-C2H2 PF00096.26 ORX91760.1 - 0.0052 17.2 12.9 0.02 15.3 1.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Lentiviral_Tat PF02998.14 ORX91760.1 - 0.0074 16.3 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 Lentiviral Tat protein zf-LYAR PF08790.11 ORX91760.1 - 0.047 13.6 0.8 0.71 9.8 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 ORX91760.1 - 2.4 9.2 13.7 1.6 9.7 1.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_M13_N PF05649.13 ORX91761.1 - 9.5e-89 298.7 0.0 1.3e-88 298.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX91761.1 - 7.9e-67 224.8 0.0 1.2e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 ORX91762.1 - 9.1e-86 288.9 0.0 1.2e-85 288.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX91762.1 - 8.3e-63 211.7 0.0 1.2e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 ORX91763.1 - 6.2e-88 296.0 0.0 8.3e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX91763.1 - 7.8e-67 224.8 0.0 1.2e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 ORX91763.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M13_N PF05649.13 ORX91764.1 - 1.4e-86 291.6 0.0 1.9e-86 291.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX91764.1 - 5.8e-66 222.0 0.0 8.6e-66 221.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 ORX91764.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 PTP_tm PF18861.1 ORX91765.1 - 0.0092 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Pkinase PF00069.25 ORX91767.1 - 3.1e-28 98.9 0.0 3.7e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91767.1 - 1.8e-12 47.1 0.0 2.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX91767.1 - 1.5e-07 30.6 0.0 1.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX91767.1 - 0.0012 18.8 0.0 1 9.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 ORX91767.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-UBR PF02207.20 ORX91768.1 - 1.2e-17 63.8 13.1 1.2e-17 63.8 13.1 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ORX91768.1 - 1.1e-13 50.7 0.1 2.8e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 ORX91768.1 - 0.0011 19.2 0.8 0.0011 19.2 0.8 4.6 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 ORX91768.1 - 0.0011 18.9 0.8 0.0011 18.9 0.8 4.4 5 1 0 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORX91768.1 - 0.0021 17.9 0.6 0.0021 17.9 0.6 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 ORX91773.1 - 5.6e-05 23.6 0.1 0.00019 21.9 0.1 1.9 1 0 0 1 1 1 1 PH domain MMM1 PF10296.9 ORX91773.1 - 0.00032 19.9 0.0 0.00032 19.9 0.0 2.6 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 ORX91773.1 - 0.097 13.1 0.1 0.097 13.1 0.1 3.2 3 2 0 3 3 3 0 Pleckstrin homology domain Pheromone PF08015.11 ORX91773.1 - 8.5 7.5 8.0 10 7.2 0.3 3.3 2 1 0 2 2 2 0 Fungal mating-type pheromone DUF4476 PF14771.6 ORX91774.1 - 0.033 14.5 0.0 0.057 13.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) BAG PF02179.16 ORX91775.1 - 2.8e-17 62.9 0.1 4.2e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 ORX91775.1 - 5.7e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORX91775.1 - 2.9e-05 24.4 0.0 7.6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Endotoxin_N PF03945.14 ORX91775.1 - 0.17 11.6 0.0 1.6 8.4 0.0 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain TauD PF02668.16 ORX91777.1 - 6.8e-42 144.1 0.3 1.3e-41 143.2 0.1 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORX91777.1 - 4.6e-08 33.6 0.0 9.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORX91777.1 - 0.025 13.7 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 CsiD Acetyltransf_10 PF13673.7 ORX91778.1 - 5e-17 62.0 0.1 5.9e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX91778.1 - 2.4e-10 40.7 0.2 2.9e-10 40.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX91778.1 - 3.2e-09 37.1 0.3 4.7e-09 36.5 0.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 ORX91778.1 - 4.7e-08 33.7 0.1 2.1e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX91778.1 - 0.00046 20.3 0.3 0.0026 17.9 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX91778.1 - 0.029 14.4 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 FR47-like protein DUF1203 PF06718.11 ORX91778.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1203) PH PF00169.29 ORX91779.1 - 2.9e-06 27.7 1.7 4.7e-06 27.1 0.8 1.9 2 0 0 2 2 2 1 PH domain FERM_f0 PF16511.5 ORX91779.1 - 0.0002 21.6 0.1 0.00076 19.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM PH_8 PF15409.6 ORX91779.1 - 0.014 15.6 0.0 0.044 14.1 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 ORX91779.1 - 0.084 13.3 2.3 0.44 11.0 1.6 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain GrpB PF04229.14 ORX91779.1 - 0.1 12.8 0.2 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 GrpB protein PH PF00169.29 ORX91780.1 - 0.0027 18.2 0.5 0.016 15.7 0.1 2.1 2 0 0 2 2 2 1 PH domain Cytochrom_C PF00034.21 ORX91781.1 - 1.3e-12 48.7 0.2 1.9e-12 48.1 0.2 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORX91781.1 - 2.3e-07 31.0 2.8 1.2e-06 28.8 2.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORX91781.1 - 0.0012 18.6 1.7 0.0068 16.1 1.7 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 ORX91781.1 - 0.017 15.8 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cyt-b5 PF00173.28 ORX91782.1 - 7.7e-12 45.2 0.2 1.1e-11 44.7 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ring_hydroxyl_A PF00848.19 ORX91782.1 - 0.091 12.7 0.4 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Peptidase_C54 PF03416.19 ORX91783.1 - 5.1e-45 154.0 0.0 5.7e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 ORX91783.1 - 0.039 13.4 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C78 Gpr1_Fun34_YaaH PF01184.19 ORX91784.1 - 7.8e-37 126.9 19.0 9.3e-37 126.6 19.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Phage_holin_1 PF04531.13 ORX91784.1 - 5.2 7.7 6.3 19 5.9 0.1 2.7 2 1 0 2 2 2 0 Bacteriophage holin Choline_transpo PF04515.12 ORX91785.1 - 8.6e-79 265.1 30.1 8.6e-79 265.1 30.1 2.5 1 1 1 2 2 2 1 Plasma-membrane choline transporter MRAP PF15183.6 ORX91785.1 - 0.025 14.5 0.7 0.025 14.5 0.7 2.8 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Cyclin_N PF00134.23 ORX91786.1 - 6.1e-05 22.8 0.1 7.7e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX91786.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Cyclin Cyclin PF08613.11 ORX91787.1 - 8.1e-26 91.3 0.6 1.4e-25 90.5 0.6 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX91787.1 - 3.3e-07 30.1 0.2 1.1e-06 28.4 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain WES_acyltransf PF03007.16 ORX91788.1 - 2.2e-24 86.6 0.0 3.6e-24 85.9 0.0 1.3 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ORX91788.1 - 9.1e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 ORX91788.1 - 2.1e-06 26.7 0.7 5.4e-05 22.0 0.1 2.1 2 0 0 2 2 2 2 Condensation domain GNAT_acetyltran PF12746.7 ORX91788.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Cyclin PF08613.11 ORX91789.1 - 2.8e-12 47.3 0.1 3.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX91789.1 - 0.00016 21.4 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Phi-29_GP4 PF05464.11 ORX91789.1 - 0.052 13.8 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) v110 PF01639.17 ORX91789.1 - 0.052 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Viral family 110 GPI-anchored PF10342.9 ORX91792.1 - 9e-16 58.4 0.2 1e-15 58.2 0.2 1.0 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pur_ac_phosph_N PF16656.5 ORX91792.1 - 0.005 17.4 0.1 0.0066 17.0 0.1 1.1 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 ORX91792.1 - 0.016 15.5 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 Fibronectin type III domain DUF3304 PF11745.8 ORX91792.1 - 0.078 13.4 0.2 0.12 12.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) DUF4249 PF14054.6 ORX91792.1 - 0.094 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) NAR2 PF16974.5 ORX91792.1 - 0.1 12.0 0.2 0.29 10.5 0.2 1.8 1 1 1 2 2 2 0 High-affinity nitrate transporter accessory FAD-oxidase_C PF02913.19 ORX91794.1 - 2.1e-53 181.5 0.0 2.8e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORX91794.1 - 1.8e-37 128.2 0.2 3.5e-37 127.2 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Aminotran_5 PF00266.19 ORX91795.1 - 4.7e-36 124.5 0.0 6.3e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORX91795.1 - 5.4e-07 29.1 0.0 6.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX91795.1 - 3.5e-06 25.8 0.0 5.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FAD-oxidase_C PF02913.19 ORX91796.1 - 5.6e-58 196.5 0.0 7.4e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORX91796.1 - 1.5e-31 109.0 2.0 3.4e-31 107.8 2.0 1.6 1 0 0 1 1 1 1 FAD binding domain LRR_6 PF13516.6 ORX91797.1 - 1.2e-06 28.1 7.6 1.5 9.1 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 ORX91797.1 - 0.017 14.9 9.3 0.36 10.6 0.0 5.3 4 2 0 4 4 4 0 Leucine rich repeat adh_short_C2 PF13561.6 ORX91797.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase LRR_1 PF00560.33 ORX91797.1 - 0.17 12.5 6.8 83 4.4 0.0 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 ORX91797.1 - 1.5 9.4 20.3 5.1 7.7 0.0 6.7 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) SDF PF00375.18 ORX91798.1 - 2.6e-108 362.6 36.0 2.9e-108 362.4 36.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LapA_dom PF06305.11 ORX91798.1 - 0.024 14.5 2.2 0.024 14.5 2.2 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain HNH_4 PF13395.6 ORX91798.1 - 0.026 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 HNH endonuclease KaiA PF07688.12 ORX91798.1 - 0.18 11.9 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 KaiA C-terminal domain tRNA_edit PF04073.15 ORX91799.1 - 9.7e-27 93.5 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Vps35 PF03635.17 ORX91800.1 - 0 1061.9 5.3 0 1061.7 5.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF758 PF05527.11 ORX91800.1 - 0.012 15.6 1.5 0.02 14.9 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF758) Ammonium_transp PF00909.21 ORX91801.1 - 1.4e-117 392.8 31.1 1.5e-117 392.6 31.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2749 PF10907.8 ORX91801.1 - 0.9 9.8 3.2 1.2 9.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF4448 PF14610.6 ORX91804.1 - 0.00031 20.6 1.0 0.0018 18.1 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Cadherin_C_2 PF16492.5 ORX91804.1 - 0.022 15.5 0.0 0.16 12.7 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal zf-H2C2_2 PF13465.6 ORX91805.1 - 4.6e-23 80.6 25.8 3.8e-09 36.5 0.1 4.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX91805.1 - 3.4e-22 77.6 27.4 2.3e-07 30.9 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX91805.1 - 4.7e-14 51.9 23.9 0.0003 21.4 0.3 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX91805.1 - 1.9e-08 34.4 7.1 0.014 15.7 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX91805.1 - 0.0002 21.6 8.4 0.56 10.7 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORX91805.1 - 0.00036 21.1 3.0 0.0058 17.2 0.8 2.9 2 2 1 3 3 3 1 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX91805.1 - 0.0088 16.7 2.9 0.0088 16.7 2.9 2.7 1 1 2 3 3 3 1 TRAF-type zinc finger HTH_18 PF12833.7 ORX91805.1 - 0.013 15.8 1.6 3.3 8.0 0.2 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain zf_UBZ PF18439.1 ORX91805.1 - 0.043 13.4 3.5 12 5.6 0.1 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 ORX91805.1 - 0.048 13.6 11.0 3.5 7.6 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 ORX91805.1 - 0.056 13.7 2.6 0.48 10.7 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon Zn-ribbon_8 PF09723.10 ORX91805.1 - 0.076 13.2 7.9 0.69 10.1 1.9 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 ORX91805.1 - 0.11 13.3 3.0 3.4 8.5 0.1 2.2 1 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_6 PF13912.6 ORX91805.1 - 0.16 12.0 0.2 0.16 12.0 0.2 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger DUF3268 PF11672.8 ORX91805.1 - 0.21 11.9 4.6 3.5 8.0 1.4 2.1 1 1 0 2 2 2 0 zinc-finger-containing domain ADK_lid PF05191.14 ORX91805.1 - 0.21 11.6 6.4 3 7.9 0.2 3.4 3 2 0 3 3 3 0 Adenylate kinase, active site lid Ribosomal_L37ae PF01780.19 ORX91805.1 - 1.1 9.4 7.1 0.38 10.9 0.4 2.5 1 1 0 2 2 2 0 Ribosomal L37ae protein family XPA_N PF01286.18 ORX91805.1 - 2 8.5 6.9 16 5.6 0.0 3.4 4 0 0 4 4 4 0 XPA protein N-terminal zf-H2C2_2 PF13465.6 ORX91806.1 - 3.9e-24 83.9 20.9 1.2e-09 38.1 0.1 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX91806.1 - 6.5e-22 76.7 24.6 2.3e-07 30.9 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX91806.1 - 1.2e-12 47.5 22.4 0.00029 21.4 0.3 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX91806.1 - 4.5e-09 36.4 3.6 0.013 15.8 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX91806.1 - 2.7e-05 24.7 2.8 0.0042 17.7 0.6 2.7 2 2 0 2 2 2 1 FOXP coiled-coil domain zf-met PF12874.7 ORX91806.1 - 0.00023 21.4 6.0 0.54 10.7 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type HTH_18 PF12833.7 ORX91806.1 - 0.0048 17.1 1.0 2.8 8.3 0.2 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain zf-TRAF PF02176.18 ORX91806.1 - 0.0051 17.5 1.9 0.0051 17.5 1.9 2.8 1 1 2 3 3 3 1 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 ORX91806.1 - 0.039 14.1 7.2 0.59 10.3 1.7 3.3 2 1 1 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 ORX91806.1 - 0.073 12.7 3.5 11 5.7 0.1 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 ORX91806.1 - 0.087 13.6 3.2 2.3 9.0 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 ORX91806.1 - 0.097 13.0 3.5 0.47 10.8 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon zf-C2HC_2 PF13913.6 ORX91806.1 - 0.098 12.6 9.7 3.4 7.7 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 ORX91806.1 - 0.15 12.4 5.2 2.5 8.4 0.9 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2H2_6 PF13912.6 ORX91806.1 - 0.16 12.0 0.2 0.16 12.0 0.2 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger Ribosomal_L37ae PF01780.19 ORX91806.1 - 0.16 12.1 0.4 0.16 12.1 0.4 2.5 1 1 0 2 2 2 0 Ribosomal L37ae protein family ADK_lid PF05191.14 ORX91806.1 - 0.48 10.5 7.4 2.9 8.0 0.3 3.4 3 2 0 3 3 3 0 Adenylate kinase, active site lid XPA_N PF01286.18 ORX91806.1 - 2.4 8.3 7.3 16 5.7 0.0 3.4 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_aberr PF17017.5 ORX91806.1 - 6.7 6.8 9.0 7 6.8 0.4 3.3 2 1 2 4 4 4 0 Aberrant zinc-finger SWIB PF02201.18 ORX91807.1 - 3.4e-33 113.3 0.1 6.6e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 ORX91807.1 - 3.9e-15 55.5 3.2 4.7e-15 55.2 1.7 2.0 2 0 0 2 2 2 1 DEK C terminal domain SRP54_N PF02881.19 ORX91807.1 - 0.061 13.6 1.4 0.061 13.6 1.4 2.8 2 1 1 3 3 3 0 SRP54-type protein, helical bundle domain DTHCT PF08070.11 ORX91807.1 - 0.61 10.9 15.0 0.21 12.3 10.9 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region BCDHK_Adom3 PF10436.9 ORX91808.1 - 3.3e-25 88.8 0.2 4.7e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX91808.1 - 6.4e-09 36.3 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORX91808.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PTSIIA_gutA PF03829.13 ORX91808.1 - 0.061 13.2 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component Cyclin PF08613.11 ORX91809.1 - 3.8e-08 33.9 0.0 4.4e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX91809.1 - 1.2e-07 31.5 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain HEAT_2 PF13646.6 ORX91810.1 - 0.0042 17.4 0.0 10 6.6 0.0 4.4 3 2 2 5 5 5 2 HEAT repeats DUF3453 PF11935.8 ORX91810.1 - 0.011 15.3 6.1 0.53 9.9 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3453) DUF3452 PF11934.8 ORX91810.1 - 0.013 15.1 0.0 0.045 13.3 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) RNA_pol_Rpb5_C PF01191.19 ORX91810.1 - 0.039 13.8 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Cnd1 PF12717.7 ORX91810.1 - 0.18 11.9 4.2 1.8 8.6 0.1 3.4 1 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORX91810.1 - 0.18 12.4 0.8 6.5 7.4 0.0 3.6 3 1 1 4 4 4 0 HEAT-like repeat Telomere_reg-2 PF10193.9 ORX91810.1 - 0.46 11.0 2.8 1.2 9.6 0.3 3.1 2 1 0 2 2 2 0 Telomere length regulation protein DUF3385 PF11865.8 ORX91810.1 - 0.7 9.8 6.6 0.73 9.7 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) Prefoldin PF02996.17 ORX91811.1 - 5.9e-20 71.4 3.3 5.9e-20 71.4 3.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit YgbB PF02542.16 ORX91811.1 - 0.01 16.1 0.7 0.014 15.6 0.6 1.4 1 1 0 1 1 1 0 YgbB family FCH PF00611.23 ORX91811.1 - 0.32 11.3 3.9 4.7 7.6 0.2 3.1 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain IMD PF08397.11 ORX91811.1 - 0.45 9.9 7.9 0.12 11.7 1.5 2.0 2 0 0 2 2 2 0 IRSp53/MIM homology domain Turandot PF07240.11 ORX91811.1 - 0.91 9.5 3.5 20 5.2 0.1 3.0 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot Trypsin PF00089.26 ORX91812.1 - 1.3e-28 100.4 0.0 1.4e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX91812.1 - 0.00024 22.0 0.1 0.00034 21.5 0.1 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain AMP-binding PF00501.28 ORX91813.1 - 4.1e-96 322.2 0.0 5e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX91813.1 - 3e-14 53.8 0.5 9e-14 52.2 0.5 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SSF PF00474.17 ORX91814.1 - 3.4e-11 42.6 13.7 3.4e-11 42.6 13.7 2.3 2 1 0 2 2 2 1 Sodium:solute symporter family ADH_N PF08240.12 ORX91815.1 - 2.3e-23 82.2 0.8 2.3e-23 82.2 0.8 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX91815.1 - 1.4e-14 54.1 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX91815.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORX91815.1 - 7.6e-05 23.8 0.0 0.00016 22.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORX91815.1 - 7.9e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORX91815.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase EIF_2_alpha PF07541.12 ORX91815.1 - 0.078 13.1 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit 3HCDH_N PF02737.18 ORX91815.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kazal_1 PF00050.21 ORX91815.1 - 0.2 11.7 1.9 2.3 8.3 0.7 2.4 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Ribonuclease PF00545.20 ORX91816.1 - 5.9e-05 23.7 0.1 8.1e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 ribonuclease MTA_R1 PF17226.2 ORX91816.1 - 0.055 13.6 0.8 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 MTA R1 domain AATase PF07247.12 ORX91817.1 - 1.5e-09 37.0 0.0 1.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase AATase PF07247.12 ORX91818.1 - 1.5e-15 56.8 0.0 5.9e-15 54.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 ORX91818.1 - 5.8e-06 25.3 0.0 0.01 14.6 0.0 2.1 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.16 ORX91818.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 ORX91818.1 - 0.0056 15.4 0.0 0.041 12.6 0.0 2.0 2 0 0 2 2 2 1 Transferase family AATase PF07247.12 ORX91820.1 - 2.2e-17 62.8 0.0 3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 ORX91820.1 - 3.5e-07 29.2 0.0 0.0083 14.8 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Transferase PF02458.15 ORX91820.1 - 0.00061 18.6 0.0 0.012 14.2 0.0 2.1 2 0 0 2 2 2 1 Transferase family WES_acyltransf PF03007.16 ORX91820.1 - 0.00092 19.1 0.0 0.0021 17.8 0.0 1.6 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 ORX91821.1 - 2e-07 30.1 0.0 0.044 12.5 0.0 3.1 3 0 0 3 3 3 3 Condensation domain WES_acyltransf PF03007.16 ORX91821.1 - 1.2e-06 28.5 0.2 0.0094 15.7 0.0 2.6 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 ORX91821.1 - 0.0005 18.8 0.0 0.037 12.7 0.0 2.9 3 0 0 3 3 3 1 Transferase family CAT PF00302.18 ORX91821.1 - 0.36 10.7 1.9 3 7.7 0.0 2.5 2 1 1 3 3 3 0 Chloramphenicol acetyltransferase Ribosomal_S7 PF00177.21 ORX91822.1 - 8.5e-34 116.3 0.9 1.1e-33 116.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e M-inducer_phosp PF06617.13 ORX91822.1 - 0.037 13.3 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase Sec1 PF00995.23 ORX91823.1 - 4.5e-17 62.5 0.1 4.7e-16 59.1 0.1 2.1 1 1 0 1 1 1 1 Sec1 family ZapD PF07072.11 ORX91823.1 - 0.0086 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Cell division protein Tetraspanin PF00335.20 ORX91824.1 - 4.5e-05 23.3 0.5 5.1e-05 23.1 0.5 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 ORX91824.1 - 0.0015 18.4 1.0 0.0016 18.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) BCD PF15461.6 ORX91824.1 - 0.0059 16.1 0.2 0.0063 16.0 0.2 1.0 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase MrpF_PhaF PF04066.13 ORX91824.1 - 0.9 10.0 6.1 2 8.8 3.2 2.7 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Phytochelatin PF05023.14 ORX91825.1 - 7.8e-78 260.5 0.0 9.2e-78 260.3 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 ORX91825.1 - 0.00023 21.8 0.0 0.00052 20.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase_C39 like family IGR PF09597.10 ORX91826.1 - 1e-20 73.5 0.8 1.6e-20 72.9 0.8 1.3 1 0 0 1 1 1 1 IGR protein motif JmjN PF02375.17 ORX91826.1 - 0.084 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 jmjN domain LigA PF07746.11 ORX91826.1 - 0.15 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit WD40 PF00400.32 ORX91827.1 - 1.6e-12 47.7 17.4 5.4e-05 23.9 0.4 7.4 7 1 1 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91827.1 - 4.6e-05 23.6 1.0 0.048 14.0 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX91827.1 - 0.096 12.5 0.2 4.3 7.2 0.0 2.2 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PPTA PF01239.22 ORX91828.1 - 3.5e-42 141.0 8.7 1.7e-09 37.1 1.3 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Mpv17_PMP22 PF04117.12 ORX91829.1 - 1.1e-09 38.4 2.6 2.5e-09 37.2 2.6 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family LON_substr_bdg PF02190.16 ORX91832.1 - 7.4e-31 107.6 0.0 1.2e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 ORX91832.1 - 2.4e-11 43.6 26.4 1.6e-05 24.9 10.6 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORX91832.1 - 1.7e-10 40.6 30.0 1.2e-06 28.3 10.5 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX91832.1 - 5.1e-10 39.1 23.5 9.9e-08 31.7 8.2 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX91832.1 - 2.7e-09 36.9 20.0 1.4e-08 34.6 5.7 3.8 3 1 1 4 4 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX91832.1 - 5.3e-09 35.8 11.5 5.3e-09 35.8 11.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX91832.1 - 7.4e-08 32.2 27.8 2e-05 24.4 12.3 2.7 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 ORX91832.1 - 2.3e-07 31.0 10.1 2.3e-07 31.0 10.1 3.9 4 0 0 4 4 4 2 Ring finger domain Prok-RING_4 PF14447.6 ORX91832.1 - 5.3e-05 23.0 7.1 5.3e-05 23.0 7.1 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORX91832.1 - 0.00047 20.4 5.8 0.00047 20.4 5.8 3.6 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ORX91832.1 - 0.017 14.9 17.9 0.11 12.3 7.7 3.4 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ORX91832.1 - 0.052 13.4 14.0 0.78 9.6 3.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 ORX91832.1 - 0.26 11.4 26.6 0.3 11.2 10.8 2.6 2 1 0 2 2 2 0 zinc RING finger of MSL2 PIN_12 PF16289.5 ORX91833.1 - 0.04 14.4 1.2 0.04 14.4 1.2 2.6 2 0 0 2 2 2 0 PIN domain DUF1844 PF08899.11 ORX91833.1 - 0.11 12.9 1.3 1 9.7 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) Bcr-Abl_Oligo PF09036.10 ORX91833.1 - 0.78 9.8 7.1 1.2 9.2 1.0 3.6 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain O-FucT PF10250.9 ORX91834.1 - 1.9e-20 73.9 0.1 2.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SNARE_assoc PF09335.11 ORX91835.1 - 2.1e-16 60.5 6.9 3.5e-16 59.8 6.9 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Lactamase_B PF00753.27 ORX91836.1 - 5.8e-24 85.2 0.2 7.9e-24 84.8 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX91836.1 - 1e-08 34.9 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 ORX91836.1 - 2.9e-07 30.4 0.5 6.4e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 ORX91836.1 - 0.027 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Gar1 PF04410.14 ORX91837.1 - 7.7e-39 132.9 0.0 9.1e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Aft1_HRA PF11786.8 ORX91837.1 - 6 7.3 27.4 27 5.2 9.7 3.3 1 1 1 2 2 2 0 Aft1 HRA domain Ribosomal_L6e PF01159.19 ORX91838.1 - 3.9e-43 146.5 1.7 3.9e-43 146.5 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORX91838.1 - 8.5e-08 32.3 0.4 8.5e-08 32.3 0.4 2.4 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain ATP-grasp_2 PF08442.10 ORX91840.1 - 1.5e-76 256.5 0.4 2.3e-76 255.9 0.1 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 ORX91840.1 - 2.8e-27 95.4 0.5 4.3e-27 94.8 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ORX91840.1 - 1.8e-07 30.8 0.1 3.6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ORX91840.1 - 0.00017 21.4 0.2 0.002 17.9 0.0 2.4 2 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 ORX91840.1 - 0.0016 18.7 0.1 0.0041 17.4 0.1 1.7 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain ATG13 PF10033.9 ORX91841.1 - 7.2e-56 189.6 0.1 1.3e-55 188.7 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 GvpD PF07088.11 ORX91841.1 - 0.14 10.7 0.1 1.3 7.5 0.1 2.0 2 0 0 2 2 2 0 GvpD gas vesicle protein Peptidase_M10 PF00413.24 ORX91842.1 - 0.036 13.9 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Matrixin Metallophos PF00149.28 ORX91843.1 - 9.1e-13 49.2 0.1 1.3e-12 48.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.25 ORX91843.1 - 0.16 11.4 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Alba PF01918.21 ORX91844.1 - 4.3e-17 61.7 0.7 6.4e-17 61.1 0.7 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 ORX91844.1 - 0.00054 19.9 0.1 0.00072 19.5 0.1 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P DUF1664 PF07889.12 ORX91846.1 - 0.1 12.7 0.6 16 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BolA PF01722.18 ORX91847.1 - 1.7e-33 114.7 0.8 2e-33 114.5 0.8 1.1 1 0 0 1 1 1 1 BolA-like protein Glyco_hydro_8 PF01270.17 ORX91848.1 - 9.7e-23 80.5 0.2 1.2e-22 80.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 Ribosomal_S4e PF00900.20 ORX91850.1 - 3.2e-36 123.1 0.1 7.1e-36 122.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX91850.1 - 2.4e-26 91.1 0.1 4.2e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORX91850.1 - 1.9e-21 75.9 6.5 4.4e-21 74.7 6.5 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORX91850.1 - 1.4e-08 34.3 0.1 3.3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORX91850.1 - 7.3e-05 22.6 3.5 7.3e-05 22.6 3.5 2.7 4 0 0 4 4 4 1 KOW motif F-actin_cap_A PF01267.17 ORX91851.1 - 3.7e-101 338.0 0.0 4.3e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit dCMP_cyt_deam_1 PF00383.23 ORX91852.1 - 2.1e-25 88.6 1.9 3.2e-25 87.9 1.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX91852.1 - 6.6e-11 42.1 0.5 1.5e-10 40.9 0.5 1.5 1 1 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 ORX91852.1 - 0.0014 19.2 0.1 0.007 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain SNAD4 PF18750.1 ORX91852.1 - 0.017 15.2 0.3 0.043 13.9 0.3 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 CoaE PF01121.20 ORX91852.1 - 0.024 14.3 0.0 0.06 13.0 0.0 1.7 1 1 1 2 2 2 0 Dephospho-CoA kinase NAD1 PF18778.1 ORX91852.1 - 0.1 12.7 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 PAS PF00989.25 ORX91853.1 - 0.00038 20.4 0.0 0.00087 19.3 0.0 1.6 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 ORX91853.1 - 0.0015 18.6 11.3 0.0015 18.6 11.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_27 PF13463.6 ORX91853.1 - 0.0049 17.3 0.0 0.0094 16.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Cyclin_N PF00134.23 ORX91854.1 - 3.8e-07 29.9 0.0 4.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX91854.1 - 3.6e-06 27.4 0.2 3.7e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Cyclin Ribosomal_L6 PF00347.23 ORX91855.1 - 8.7e-31 106.4 3.9 1.7e-16 60.7 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Exotox-A_cataly PF09009.10 ORX91855.1 - 0.067 12.9 0.3 0.85 9.3 0.1 2.3 2 1 1 3 3 3 0 Exotoxin A catalytic NAPRTase PF04095.16 ORX91856.1 - 3.8e-66 223.1 0.1 5.7e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 ORX91856.1 - 3.6e-33 114.6 1.3 6.7e-33 113.7 1.3 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3821 PF12863.7 ORX91856.1 - 0.037 13.9 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Glyco_hydro_17 PF00332.18 ORX91856.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 DUF2103 PF09876.9 ORX91857.1 - 0.034 14.1 5.5 0.32 11.0 0.1 3.5 3 1 0 3 3 3 0 Predicted metal-binding protein (DUF2103) RNase_T PF00929.24 ORX91858.1 - 0.00011 22.7 0.6 0.00035 21.1 0.2 1.8 1 1 1 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORX91858.1 - 0.0047 16.6 0.8 0.03 14.0 0.2 2.5 1 1 1 2 2 2 1 3'-5' exonuclease DUF3673 PF12425.8 ORX91858.1 - 0.25 11.3 1.2 0.9 9.5 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3673) eIF-5_eIF-2B PF01873.17 ORX91859.1 - 2.8e-42 143.3 0.1 5.2e-42 142.4 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORX91859.1 - 0.042 13.4 0.3 0.099 12.2 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 ORX91859.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DUF1754 PF08555.10 ORX91859.1 - 0.6 10.9 37.1 1.2 9.9 9.0 3.1 1 1 2 3 3 3 0 Eukaryotic family of unknown function (DUF1754) CDC45 PF02724.14 ORX91859.1 - 0.72 8.1 13.4 0.9 7.7 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein LZ_Tnp_IS66 PF13007.7 ORX91859.1 - 1.8 9.4 0.0 1.8 9.4 0.0 3.3 2 1 1 3 3 3 0 Transposase C of IS166 homeodomain CDC27 PF09507.10 ORX91859.1 - 2.9 7.2 30.1 3.7 6.8 30.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GMP_synt_C PF00958.22 ORX91860.1 - 2.1e-45 152.7 0.3 4.4e-45 151.7 0.3 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ORX91860.1 - 7.7e-32 110.6 0.0 1.5e-31 109.6 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 ORX91860.1 - 3.5e-09 36.2 0.1 4.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 ORX91860.1 - 2.3e-06 27.5 0.1 4.1e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 ORX91860.1 - 0.0019 17.8 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORX91860.1 - 0.0038 16.1 0.1 0.0081 15.0 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 ORX91860.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family FTR_C PF02741.15 ORX91871.1 - 0.18 11.8 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 FTR, proximal lobe RhoGAP-FF1 PF16512.5 ORX91872.1 - 0.0018 18.9 3.7 0.88 10.3 0.1 2.7 2 2 0 2 2 2 2 p190-A and -B Rho GAPs FF domain DUF4848 PF16140.5 ORX91872.1 - 0.024 14.2 3.2 1.8 8.1 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4848) Stevor PF17410.2 ORX91872.1 - 0.036 13.6 1.9 0.05 13.1 1.1 1.5 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame Acetyltransf_6 PF13480.7 ORX91872.1 - 0.082 13.1 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4446 PF14584.6 ORX91872.1 - 0.097 12.7 2.7 4.6 7.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) PBECR5 PF18814.1 ORX91872.1 - 0.21 11.5 5.7 0.37 10.7 4.2 1.7 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 DNA_pol_B PF00136.21 ORX91873.1 - 2.5e-152 507.8 1.6 4.5e-152 506.9 1.6 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORX91873.1 - 1.3e-80 271.0 0.3 7.4e-80 268.6 0.1 2.3 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORX91873.1 - 1.6e-19 70.2 9.2 3.5e-19 69.0 9.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORX91873.1 - 7.7e-06 25.0 1.4 2.2e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 ORX91873.1 - 0.0014 18.3 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ORX91873.1 - 0.018 15.1 0.5 0.15 12.1 0.2 2.6 2 1 0 2 2 2 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 ORX91873.1 - 0.061 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 3'-5' exonuclease TBCC PF07986.12 ORX91874.1 - 2.4e-30 104.7 0.5 4e-30 104.0 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 ORX91874.1 - 3e-11 43.8 1.4 6.4e-11 42.7 1.4 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Chorion_3 PF05387.11 ORX91874.1 - 0.057 13.1 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Chorion family 3 SH3_9 PF14604.6 ORX91875.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 ORX91875.1 - 0.00025 21.2 0.0 0.00053 20.1 0.0 1.5 1 0 0 1 1 1 1 Podoplanin SH3_1 PF00018.28 ORX91875.1 - 0.0024 17.5 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX91875.1 - 0.0053 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Stevor PF17410.2 ORX91875.1 - 0.0062 16.1 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame MFS_1 PF07690.16 ORX91875.1 - 0.028 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Amnionless PF14828.6 ORX91875.1 - 0.032 13.1 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF485 PF04341.12 ORX91875.1 - 0.094 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UL45 PF05473.12 ORX91875.1 - 0.097 12.3 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like RIFIN PF02009.16 ORX91875.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Rifin PepSY_TM PF03929.16 ORX91875.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF2207 PF09972.9 ORX91875.1 - 0.25 10.1 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 ORX91875.1 - 1.3 8.5 12.3 2.7 7.5 12.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-RING_2 PF13639.6 ORX91876.1 - 1.1e-12 48.0 8.3 1.1e-12 48.0 8.3 2.4 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 ORX91876.1 - 9e-09 34.9 6.0 9e-09 34.9 6.0 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORX91876.1 - 7.6e-08 32.5 9.0 2.6e-07 30.8 8.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORX91876.1 - 1.8e-07 30.9 7.7 1.8e-07 30.9 7.7 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX91876.1 - 6.5e-06 25.9 8.0 6.5e-06 25.9 8.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX91876.1 - 0.00011 22.0 6.9 0.00011 22.0 6.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORX91876.1 - 0.00058 19.9 5.7 0.002 18.2 5.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORX91876.1 - 0.00065 19.7 8.2 0.0022 18.0 5.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORX91876.1 - 0.0019 18.0 6.2 0.0019 18.0 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORX91876.1 - 0.0023 18.0 4.0 0.0053 16.9 4.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORX91876.1 - 0.0093 15.8 5.4 0.0093 15.8 5.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORX91876.1 - 0.027 14.1 6.8 0.083 12.5 6.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORX91876.1 - 0.033 14.4 8.3 0.23 11.7 8.0 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 ORX91876.1 - 0.091 12.9 9.0 0.2 11.8 9.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.6 ORX91876.1 - 0.28 11.4 5.8 0.14 12.4 3.4 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain Chitin_synth_2 PF03142.15 ORX91876.1 - 0.76 8.3 5.3 1.2 7.7 5.3 1.2 1 0 0 1 1 1 0 Chitin synthase zf-RING-like PF08746.11 ORX91876.1 - 1.3 9.4 7.1 3.7 8.0 7.1 1.8 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.6 ORX91876.1 - 2.4 8.5 8.2 2.4 8.5 6.4 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain Pex24p PF06398.11 ORX91877.1 - 9.7e-09 34.7 6.0 1.7e-08 33.8 6.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Hist_deacetyl PF00850.19 ORX91878.1 - 4.2e-83 279.3 0.2 6.8e-83 278.7 0.2 1.3 1 0 0 1 1 1 1 Histone deacetylase domain PITH PF06201.13 ORX91879.1 - 6.1e-46 156.4 0.0 7.8e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain FA_desaturase PF00487.24 ORX91879.1 - 5.6 6.7 8.7 7.4 6.3 8.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Cyclin_N PF00134.23 ORX91880.1 - 5.4e-43 145.8 1.4 6.3e-42 142.3 0.4 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX91880.1 - 4.6e-33 113.8 0.5 1.6e-32 112.1 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain eIF-6 PF01912.18 ORX91881.1 - 1.2e-84 282.7 0.2 1.6e-84 282.2 0.2 1.2 1 0 0 1 1 1 1 eIF-6 family DUF126 PF01989.16 ORX91881.1 - 0.13 12.1 0.0 22 4.9 0.0 2.6 2 0 0 2 2 2 0 Aconitase X swivel domain DUF1690 PF07956.11 ORX91882.1 - 1.3e-19 71.0 12.7 9.5e-18 65.0 12.7 2.2 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 ORX91882.1 - 0.0021 18.1 5.3 0.0026 17.8 5.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CHCH PF06747.13 ORX91882.1 - 0.011 15.9 1.2 0.022 14.9 1.2 1.5 1 0 0 1 1 1 0 CHCH domain FOP_dimer PF09398.10 ORX91883.1 - 5.5e-07 29.8 0.1 8e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 ORX91883.1 - 2.7e-06 26.3 0.0 4.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 LisH DEK_C PF08766.11 ORX91883.1 - 0.059 13.3 0.1 0.44 10.5 0.0 2.4 2 1 0 2 2 2 0 DEK C terminal domain DUF4451 PF14616.6 ORX91884.1 - 1.2e-19 70.7 9.4 2.1e-19 69.9 9.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) Calreticulin PF00262.18 ORX91885.1 - 9.3e-80 268.2 11.9 1.2e-60 205.4 0.4 2.8 2 1 1 3 3 3 2 Calreticulin family UPF0669 PF17065.5 ORX91885.1 - 0.66 9.7 2.0 1.2 8.9 2.0 1.3 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 CDC45 PF02724.14 ORX91885.1 - 2.8 6.1 13.2 4 5.6 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1g PF09334.11 ORX91886.1 - 5.1e-152 506.2 0.3 6.5e-152 505.8 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORX91886.1 - 5.6e-10 38.1 1.7 3.3e-06 25.7 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORX91886.1 - 0.00053 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORX91886.1 - 0.00097 18.6 0.0 0.0035 16.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zinc-ribbons_6 PF07191.12 ORX91886.1 - 0.12 12.4 6.9 0.39 10.7 6.9 1.9 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 ORX91886.1 - 0.12 12.4 8.4 1.3 9.1 8.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ORX91886.1 - 0.28 11.2 3.3 0.94 9.5 2.8 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Trypsin PF00089.26 ORX91887.1 - 4.3e-37 128.1 0.1 6.3e-37 127.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX91887.1 - 2.7e-07 31.6 0.1 4e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain ATP-synt_ab PF00006.25 ORX91888.1 - 1.3e-68 230.8 0.0 2.5e-68 229.9 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX91888.1 - 6.7e-12 45.8 0.6 1.3e-11 44.8 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 ORX91888.1 - 0.093 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) VSP PF03302.13 ORX91889.1 - 0.11 11.3 0.4 0.14 11.0 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4448 PF14610.6 ORX91889.1 - 0.23 11.2 2.1 0.34 10.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) Homeodomain PF00046.29 ORX91890.1 - 5.4e-57 189.5 21.7 1.7e-09 37.4 0.0 8.4 8 0 0 8 8 8 7 Homeodomain Homeobox_KN PF05920.11 ORX91890.1 - 1.7e-18 66.2 21.8 0.039 13.9 0.2 8.0 8 0 0 8 8 8 7 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX91890.1 - 0.0013 18.6 0.0 10 6.1 0.0 4.5 5 0 0 5 5 5 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 ORX91890.1 - 0.0087 15.5 3.9 21 4.7 0.1 5.7 6 0 0 6 6 6 1 Homeodomain leucine-zipper encoding, Homez HOCHOB PF17943.1 ORX91890.1 - 0.94 10.2 3.5 54 4.5 0.0 4.4 5 1 0 5 5 5 0 Homeobox-cysteine loop-homeobox Ras PF00071.22 ORX91891.1 - 5.3e-54 182.2 0.2 6.1e-54 182.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX91891.1 - 2.5e-20 72.9 0.1 3.5e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX91891.1 - 9.2e-09 35.0 0.1 1e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX91891.1 - 0.00029 20.4 0.4 0.00069 19.2 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX91891.1 - 0.00037 20.5 0.1 0.00067 19.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORX91891.1 - 0.0098 15.1 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 ORX91891.1 - 0.012 15.5 1.2 2.7 7.9 0.6 2.3 1 1 0 2 2 2 0 RsgA GTPase BRCT_2 PF16589.5 ORX91892.1 - 4.2e-13 49.5 0.2 9.8e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORX91892.1 - 2.2e-11 43.9 0.0 8.9e-07 29.2 0.1 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ORX91892.1 - 2.1e-05 24.3 0.1 0.0001 22.1 0.0 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 ORX91892.1 - 0.0028 17.6 0.2 0.047 13.6 0.3 2.4 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 ORX91892.1 - 0.012 15.9 0.3 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 ORX91892.1 - 0.014 15.5 0.2 0.17 12.0 0.0 2.7 2 1 1 3 3 3 0 BRCA1 C Terminus (BRCT) domain Glypican PF01153.19 ORX91892.1 - 0.019 13.8 0.4 0.019 13.8 0.4 1.6 2 0 0 2 2 2 0 Glypican Pyocin_S PF06958.12 ORX91892.1 - 0.044 14.3 2.0 0.19 12.3 0.1 2.2 1 1 1 2 2 2 0 S-type Pyocin TPR_14 PF13428.6 ORX91893.1 - 1e-18 66.4 11.6 0.045 14.6 0.1 11.2 10 2 2 12 12 10 2 Tetratricopeptide repeat Suf PF05843.14 ORX91893.1 - 1.3e-14 54.9 18.1 0.00015 21.8 4.4 6.1 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 ORX91893.1 - 6.2e-14 52.3 2.5 0.079 13.5 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORX91893.1 - 1.2e-08 35.0 12.9 0.053 13.5 0.0 6.9 8 0 0 8 8 7 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 ORX91893.1 - 3.7e-07 29.6 1.2 0.011 14.9 0.3 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 ORX91893.1 - 1.5e-06 27.5 9.6 0.00029 20.1 0.1 4.5 3 1 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 ORX91893.1 - 6.1e-06 26.0 26.9 0.066 13.4 0.0 9.7 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX91893.1 - 3.9e-05 23.5 10.3 0.32 11.3 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORX91893.1 - 0.00016 21.8 5.9 1.2 9.3 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX91893.1 - 0.00045 20.4 6.2 3.3 8.1 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX91893.1 - 0.00099 19.7 6.6 2.1 9.1 0.1 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX91893.1 - 0.0011 18.7 5.2 6.9 6.7 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORX91893.1 - 0.0024 18.1 11.7 18 6.0 0.0 7.4 8 1 0 8 8 6 0 Tetratricopeptide repeat MIT PF04212.18 ORX91893.1 - 0.0053 16.8 0.6 4.4 7.4 0.0 4.1 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 ORX91893.1 - 0.0076 16.8 5.4 85 4.1 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX91893.1 - 0.0092 15.9 1.9 14 6.0 0.0 5.6 7 0 0 7 7 4 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 ORX91893.1 - 0.014 15.5 0.1 0.29 11.2 0.0 2.7 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein RhoGAP-FF1 PF16512.5 ORX91893.1 - 0.014 16.0 1.2 27 5.5 0.0 4.5 4 0 0 4 4 4 0 p190-A and -B Rho GAPs FF domain RPN7 PF10602.9 ORX91893.1 - 0.03 14.0 0.2 0.19 11.4 0.0 2.5 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_4 PF07721.14 ORX91893.1 - 0.045 14.4 0.6 60 4.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat SNAP PF14938.6 ORX91893.1 - 0.076 12.4 7.2 0.91 8.9 0.1 4.4 4 2 0 5 5 5 0 Soluble NSF attachment protein, SNAP HAT PF02184.16 ORX91893.1 - 0.34 10.9 18.0 31 4.6 0.3 8.0 8 1 0 8 8 8 0 HAT (Half-A-TPR) repeat TPR_10 PF13374.6 ORX91893.1 - 2 8.4 7.5 25 4.9 0.0 5.2 7 0 0 7 7 4 0 Tetratricopeptide repeat PFU PF09070.11 ORX91894.1 - 0.0027 18.0 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Telomere_Sde2_2 PF13297.6 ORX91894.1 - 0.033 13.8 0.2 0.074 12.7 0.2 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal HMG_box PF00505.19 ORX91895.1 - 6.1e-21 74.6 1.9 7.8e-21 74.3 1.9 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX91895.1 - 1.9e-14 54.0 2.8 2.6e-14 53.6 2.8 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 ORX91895.1 - 0.00016 21.6 1.3 0.00018 21.4 1.0 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 ORX91895.1 - 0.0085 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain DinB_2 PF12867.7 ORX91896.1 - 6.1e-05 23.5 0.1 8.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 ORX91896.1 - 0.00015 21.8 0.2 0.00018 21.5 0.2 1.1 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.8 ORX91896.1 - 0.018 15.7 0.0 0.02 15.6 0.0 1.2 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain CRIC_ras_sig PF10534.9 ORX91896.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras VWA_2 PF13519.6 ORX91897.1 - 1.5e-29 102.8 0.2 1.4e-28 99.7 0.1 2.6 3 1 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 ORX91897.1 - 2e-13 50.6 0.1 3.2e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 ORX91897.1 - 4.3e-11 43.4 0.7 1e-10 42.2 0.7 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 ORX91897.1 - 2.2e-10 39.7 16.1 0.00037 20.2 1.1 3.5 3 0 0 3 3 3 3 Ubiquitin interaction motif Sec23_trunk PF04811.15 ORX91897.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain BCDHK_Adom3 PF10436.9 ORX91898.1 - 1.9e-15 57.1 0.4 2.9e-15 56.5 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX91898.1 - 3.6e-11 43.6 0.0 2.1e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORX91898.1 - 5.6e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RdRP PF05183.12 ORX91899.1 - 3.8e-176 587.2 0.0 4.9e-176 586.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 ORX91899.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 ORX91900.1 - 6.2e-15 54.8 16.0 6.2e-15 54.8 16.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX91900.1 - 2.2e-06 27.4 16.3 3.8e-06 26.7 16.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORX91900.1 - 2.2e-05 24.7 17.5 3.7e-05 23.9 17.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORX91900.1 - 0.02 14.8 15.5 0.033 14.1 15.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORX91900.1 - 0.44 10.4 17.4 0.76 9.7 17.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 ORX91900.1 - 0.74 9.5 17.1 0.1 12.3 12.7 1.9 2 1 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 ORX91900.1 - 6.9 6.6 17.8 1.5 8.7 13.7 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORX91900.1 - 9.7 6.3 14.0 7.7 6.6 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger CsbD PF05532.12 ORX91902.1 - 1.2e-20 73.2 21.6 1.5e-10 40.8 7.3 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91902.1 - 0.018 15.2 1.4 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91903.1 - 3.9e-20 71.5 23.0 3.1e-10 39.8 8.5 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91904.1 - 2.4e-21 75.4 21.0 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91904.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91905.1 - 2.9e-21 75.1 22.1 2.8e-11 43.1 7.5 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91906.1 - 2.9e-21 75.1 20.5 3e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91906.1 - 0.03 14.5 1.1 1.8 8.7 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A Nexin_C PF08628.12 ORX91906.1 - 0.14 12.8 0.4 3 8.4 0.1 2.0 1 1 1 2 2 2 0 Sorting nexin C terminal CsbD PF05532.12 ORX91907.1 - 7e-22 77.1 20.8 7e-12 45.1 6.4 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91907.1 - 0.016 15.4 1.0 1.6 8.9 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91908.1 - 3.2e-21 75.0 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91908.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91909.1 - 3.3e-21 74.9 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91909.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91910.1 - 3.2e-21 75.0 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91910.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91911.1 - 3.2e-21 75.0 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91911.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91912.1 - 8.1e-24 83.3 25.7 6.2e-10 38.8 1.8 5.3 2 1 3 5 5 5 4 CsbD-like GTA_holin_3TM PF11351.8 ORX91912.1 - 5.1 7.7 6.0 1.3 9.5 0.2 2.3 2 1 0 2 2 2 0 Holin of 3TMs, for gene-transfer release CsbD PF05532.12 ORX91913.1 - 3.2e-21 75.0 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91913.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91914.1 - 3.2e-21 75.0 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91914.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91915.1 - 3.2e-21 75.0 21.2 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91915.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91916.1 - 2.4e-21 75.4 21.0 3.1e-11 43.0 6.7 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91916.1 - 0.02 15.1 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91917.1 - 6.6e-21 74.0 20.8 6.3e-11 42.0 6.2 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91917.1 - 0.016 15.4 0.9 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91918.1 - 4.7e-21 74.4 20.5 6e-11 42.1 6.2 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91919.1 - 3.4e-19 68.5 10.5 5.5e-10 39.0 3.1 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91920.1 - 1.3e-11 44.2 21.4 1.1e-10 41.3 7.0 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91921.1 - 2.3e-21 75.4 21.4 2.4e-11 43.3 6.9 2.0 1 1 1 2 2 2 2 CsbD-like FimA PF16970.5 ORX91921.1 - 0.015 15.5 1.0 1.4 9.1 0.1 2.2 1 1 1 2 2 2 0 Type-1 fimbrial protein, A CsbD PF05532.12 ORX91922.1 - 2.7e-21 75.2 19.9 6.1e-12 45.2 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91923.1 - 2.7e-21 75.2 19.9 6.1e-12 45.2 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91924.1 - 2.7e-21 75.2 19.9 6.1e-12 45.2 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91925.1 - 2.7e-21 75.2 19.9 6.1e-12 45.2 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91926.1 - 2.7e-21 75.2 19.9 6.1e-12 45.2 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORX91927.1 - 3.5e-05 23.6 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 CsbD-like Cellulase PF00150.18 ORX91928.1 - 1.6e-10 40.9 0.2 1.6e-10 40.9 0.2 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Sigma_reg_N PF13800.6 ORX91928.1 - 0.033 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Conotoxin PF02950.17 ORX91928.1 - 0.15 13.1 0.0 0.34 11.9 0.0 1.6 1 0 0 1 1 1 0 Conotoxin SP_C-Propep PF08999.10 ORX91928.1 - 0.17 11.7 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF5383 PF17355.2 ORX91928.1 - 0.25 11.7 0.2 0.41 11.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) COX6C PF02937.15 ORX91928.1 - 1.4 9.1 3.5 2.4 8.3 0.0 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc V_ATPase_I PF01496.19 ORX91929.1 - 2.6e-79 267.2 0.0 2.9e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 ORX91929.1 - 0.08 13.6 2.2 3.6 8.3 0.8 2.7 2 0 0 2 2 2 0 SlyX Pkinase PF00069.25 ORX91930.1 - 9.3e-12 44.9 0.0 1.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91930.1 - 1.3e-06 28.0 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX91930.1 - 4.2e-06 25.8 0.0 5.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORX91930.1 - 0.0011 18.4 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX91930.1 - 0.056 12.4 0.0 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 ORX91931.1 - 0.0026 17.2 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DASH_Dad2 PF08654.10 ORX91933.1 - 7.2e-14 52.0 0.0 8.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 TACC_C PF05010.14 ORX91933.1 - 0.051 13.4 0.1 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FeThRed_A PF02941.15 ORX91933.1 - 0.059 13.5 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain GWT1 PF06423.12 ORX91934.1 - 2.8e-36 124.9 0.7 2.8e-36 124.9 0.7 2.4 3 0 0 3 3 3 1 GWT1 V_ATPase_I PF01496.19 ORX91935.1 - 0 1038.7 0.0 0 1038.2 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family THP2 PF09432.10 ORX91935.1 - 0.011 15.7 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 Tho complex subunit THP2 Atg14 PF10186.9 ORX91935.1 - 0.12 11.4 4.7 0.9 8.6 1.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 ORX91936.1 - 0 1051.1 2.2 0 1050.6 2.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LSM PF01423.22 ORX91936.1 - 0.0014 18.3 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 LSM domain THP2 PF09432.10 ORX91936.1 - 0.0031 17.6 4.2 0.0033 17.5 0.7 2.3 2 0 0 2 2 2 1 Tho complex subunit THP2 HBM PF16591.5 ORX91936.1 - 0.0047 16.4 1.2 0.0047 16.4 1.2 2.3 3 0 0 3 3 2 1 Helical bimodular sensor domain ABC_tran_CTD PF16326.5 ORX91936.1 - 0.0093 16.2 3.3 0.0093 16.2 3.3 2.0 2 0 0 2 2 1 1 ABC transporter C-terminal domain LOH1CR12 PF10158.9 ORX91936.1 - 0.018 15.1 4.5 0.074 13.1 0.2 2.5 2 0 0 2 2 2 0 Tumour suppressor protein Phage_GP20 PF06810.11 ORX91936.1 - 0.023 14.5 0.2 0.059 13.2 0.2 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 PI3K_P85_iSH2 PF16454.5 ORX91936.1 - 0.033 13.8 4.7 0.18 11.4 3.6 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FTA4 PF13093.6 ORX91936.1 - 0.087 12.7 1.8 0.18 11.7 1.8 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CCDC-167 PF15188.6 ORX91936.1 - 0.11 12.8 4.3 0.073 13.4 1.7 2.0 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 Mod_r PF07200.13 ORX91936.1 - 0.12 12.5 4.6 0.31 11.2 4.6 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad2 PF08654.10 ORX91936.1 - 0.13 12.7 4.5 1.9 9.0 0.4 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 SnAC PF14619.6 ORX91936.1 - 0.14 12.8 0.7 0.27 11.8 0.7 1.5 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Cob_adeno_trans PF01923.18 ORX91936.1 - 0.16 12.1 1.9 0.24 11.5 0.6 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase OmpH PF03938.14 ORX91936.1 - 0.22 11.8 3.7 0.39 11.0 1.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FapA PF03961.13 ORX91936.1 - 0.29 9.7 5.9 0.15 10.6 1.5 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A XhlA PF10779.9 ORX91936.1 - 0.3 11.3 6.8 0.32 11.2 1.5 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DivIVA PF05103.13 ORX91936.1 - 0.34 11.0 7.8 0.12 12.4 2.4 2.2 2 0 0 2 2 2 0 DivIVA protein DUF948 PF06103.11 ORX91936.1 - 0.35 11.1 7.5 1.7 9.0 0.3 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.10 ORX91936.1 - 0.36 11.1 4.1 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil CLZ PF16526.5 ORX91936.1 - 0.5 10.8 6.3 0.7 10.3 1.1 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2730 PF10805.8 ORX91936.1 - 0.55 10.4 5.9 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Laminin_II PF06009.12 ORX91936.1 - 0.74 9.8 4.9 8.8 6.3 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 ORX91936.1 - 0.75 9.8 2.6 15 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 ORX91936.1 - 2.2 9.0 5.2 8.5 7.1 2.6 2.5 2 0 0 2 2 2 0 SlyX HWE_HK PF07536.14 ORX91936.1 - 2.6 8.8 6.5 2.4 8.9 1.4 2.4 2 0 0 2 2 2 0 HWE histidine kinase FlaC_arch PF05377.11 ORX91936.1 - 3 8.3 7.5 1 9.8 2.7 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 ORX91936.1 - 3.5 7.7 4.7 8.5 6.4 0.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 ORX91936.1 - 7.2 6.9 7.6 2.6 8.3 2.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 ORX91936.1 - 7.3 7.0 8.6 0.3 11.4 0.9 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 ORX91936.1 - 7.8 6.7 6.9 5.7 7.1 1.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family G10 PF01125.17 ORX91936.1 - 9.6 6.0 5.6 2.2 8.0 1.8 1.8 2 0 0 2 2 2 0 G10 protein GAS2 PF02187.17 ORX91937.1 - 2.4e-13 50.0 0.0 9.2e-13 48.1 0.0 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.21 ORX91937.1 - 0.0017 18.8 0.2 0.0017 18.8 0.2 7.3 4 2 3 7 7 7 1 Spectrin repeat Flagellin_C PF00700.21 ORX91937.1 - 0.063 13.7 0.5 6.7 7.2 0.1 3.1 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region EIN3 PF04873.13 ORX91937.1 - 0.1 11.9 0.6 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethylene insensitive 3 eIF3m_C_helix PF18005.1 ORX91937.1 - 0.24 11.2 3.1 7.7 6.3 0.5 2.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix COG2 PF06148.11 ORX91937.1 - 3.1 7.9 17.3 0.71 10.0 1.3 5.7 5 2 1 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 LMP PF04778.12 ORX91937.1 - 3.8 7.4 18.2 1.2 9.0 0.0 4.8 3 1 1 4 4 4 0 LMP repeated region DUF2205 PF10224.9 ORX91937.1 - 5.1 7.2 8.2 9.8 6.2 1.9 3.8 2 1 1 3 3 3 0 Short coiled-coil protein DUF948 PF06103.11 ORX91937.1 - 7.2 6.9 9.7 2.4e+02 2.0 0.0 5.9 4 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) CH PF00307.31 ORX91939.1 - 1.4e-40 137.8 1.4 1.2e-21 76.9 0.8 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORX91939.1 - 1.2e-05 25.1 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain DUF1942 PF09167.11 ORX91939.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) TruD PF01142.18 ORX91940.1 - 1.2e-84 284.6 0.0 2e-81 274.0 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) YkuD PF03734.14 ORX91941.1 - 1.1 9.7 5.9 4.6 7.7 5.9 1.9 1 1 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF935 PF06074.12 ORX91946.1 - 0.032 13.0 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) FAM194 PF14977.6 ORX91948.1 - 0.071 12.4 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 FAM194 protein TcfC PF16967.5 ORX91949.1 - 0.049 13.1 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 E-set like domain Toast_rack_N PF17115.5 ORX91949.1 - 0.12 12.6 0.1 13 6.1 0.0 3.3 3 0 0 3 3 3 0 N-terminal domain of toast_rack, DUF2154 DAO PF01266.24 ORX91950.1 - 5.5e-38 131.5 0.0 6.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX91950.1 - 7e-07 29.4 0.1 1.6e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORX91950.1 - 8.1e-05 23.1 0.0 0.0003 21.3 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX91950.1 - 0.00013 21.1 0.6 0.00025 20.3 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX91950.1 - 0.00039 19.7 0.1 0.00088 18.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORX91950.1 - 0.0004 19.4 0.9 0.36 9.6 0.7 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.6 ORX91950.1 - 0.0009 19.6 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.22 ORX91950.1 - 0.0012 18.1 0.7 0.0024 17.0 0.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORX91950.1 - 0.0018 17.6 0.1 0.0037 16.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORX91950.1 - 0.0025 17.1 0.2 0.024 13.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 ORX91950.1 - 0.0031 16.9 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORX91950.1 - 0.0066 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORX91950.1 - 0.055 12.7 0.1 0.099 11.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb2_6 PF00562.28 ORX91950.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 FAD_oxidored PF12831.7 ORX91950.1 - 0.13 11.5 3.2 0.35 10.2 0.7 2.5 2 1 0 3 3 3 0 FAD dependent oxidoreductase GFO_IDH_MocA PF01408.22 ORX91951.1 - 8.6e-13 49.2 0.0 3e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 ORX91951.1 - 0.0044 17.4 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 ORX91951.1 - 0.01 16.5 0.0 0.033 14.9 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain CoA_binding_2 PF13380.6 ORX91951.1 - 0.037 14.5 0.0 0.083 13.4 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain PI3_PI4_kinase PF00454.27 ORX91952.1 - 7.6e-48 163.5 0.0 1e-47 163.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Stomoxyn PF11585.8 ORX91952.1 - 0.17 11.9 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn ABC_tran PF00005.27 ORX91953.1 - 8.3e-30 104.1 0.0 1.7e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX91953.1 - 5.1e-21 75.2 16.1 1e-20 74.2 15.5 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX91953.1 - 3.2e-15 56.7 0.8 2.1e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORX91953.1 - 0.0024 18.4 0.1 0.0052 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORX91953.1 - 0.017 14.6 0.0 0.48 9.8 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX91953.1 - 0.096 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORX91953.1 - 0.12 12.1 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORX91953.1 - 0.13 11.6 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RabGAP-TBC PF00566.18 ORX91954.1 - 6.6e-36 124.0 2.1 8.7e-36 123.6 2.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MLD PF11647.8 ORX91954.1 - 0.0057 16.9 0.2 20 5.5 0.0 3.5 3 0 0 3 3 3 1 Membrane Localization Domain GCP5-Mod21 PF14609.6 ORX91954.1 - 0.015 13.6 0.5 0.022 13.2 0.5 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DUF3848 PF12959.7 ORX91954.1 - 0.033 14.2 1.6 0.047 13.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) EF-hand_4 PF12763.7 ORX91956.1 - 3.2e-26 91.3 0.1 1.3e-19 70.0 0.0 2.7 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 ORX91956.1 - 4.1e-23 82.6 18.1 7.8e-23 81.7 16.1 2.3 2 1 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 ORX91956.1 - 1.3e-05 24.4 0.9 3.6e-05 23.0 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORX91956.1 - 0.00014 22.2 6.5 0.018 15.5 0.1 3.5 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.6 ORX91956.1 - 0.011 15.6 0.2 0.034 14.0 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 ORX91956.1 - 0.062 13.3 0.9 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Eaf7 PF07904.13 ORX91956.1 - 0.13 12.6 5.9 0.38 11.2 5.9 1.9 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 Golgin_A5 PF09787.9 ORX91956.1 - 1.7 8.0 23.8 0.64 9.4 21.1 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 ORX91956.1 - 1.8 8.1 12.9 2.7 7.5 12.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UQ_con PF00179.26 ORX91957.1 - 1.4e-51 173.9 0.0 1.5e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HMG_box PF00505.19 ORX91959.1 - 3.1e-13 49.9 2.2 3.1e-13 49.9 2.2 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 ORX91959.1 - 7.9e-13 48.6 0.6 1.7e-12 47.6 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 ORX91959.1 - 6.9e-10 39.4 2.2 6.9e-10 39.4 2.2 1.8 1 1 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 ORX91959.1 - 2.9e-09 36.9 1.4 4.2e-09 36.4 0.1 2.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 ORX91959.1 - 0.002 18.1 0.1 0.013 15.5 0.0 2.3 3 0 0 3 3 3 1 NAB conserved region 1 (NCD1) AA_permease PF00324.21 ORX91960.1 - 5.1e-135 450.7 44.0 5.8e-135 450.6 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX91960.1 - 2e-43 148.8 48.9 2.5e-43 148.5 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease Rer1 PF03248.13 ORX91960.1 - 0.16 11.7 0.9 0.87 9.3 0.1 2.5 2 0 0 2 2 2 0 Rer1 family DUF1438 PF07270.11 ORX91961.1 - 0.23 11.6 2.6 6.2 6.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1438) Whi5 PF08528.11 ORX91963.1 - 7.1e-08 31.9 0.0 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Whi5 like HMG_CoA_synt_C PF08540.10 ORX91964.1 - 1.3e-100 336.7 0.2 1.6e-100 336.4 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ORX91964.1 - 1.3e-89 298.7 0.1 1.9e-89 298.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 ORX91964.1 - 0.0072 16.2 0.1 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ras PF00071.22 ORX91965.1 - 6e-63 211.3 0.1 7.1e-63 211.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX91965.1 - 5e-36 123.5 0.1 7.7e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX91965.1 - 9.9e-14 51.2 0.1 1.2e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX91965.1 - 1.8e-07 31.2 0.1 2.9e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX91965.1 - 8.4e-05 22.5 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 ORX91965.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX91965.1 - 0.00026 20.6 0.1 0.00092 18.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORX91965.1 - 0.0038 17.5 0.1 0.048 13.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX91965.1 - 0.0061 17.0 0.0 0.0096 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORX91965.1 - 0.0069 15.8 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 ORX91965.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORX91965.1 - 0.015 15.8 0.2 0.024 15.2 0.2 1.5 1 1 0 1 1 1 0 ABC transporter MgpC PF05220.12 ORX91965.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 MgpC protein precursor AAA_7 PF12775.7 ORX91965.1 - 0.041 13.4 0.0 0.096 12.2 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORX91965.1 - 0.051 13.3 0.3 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain GDP_Man_Dehyd PF16363.5 ORX91965.1 - 0.052 12.9 0.2 0.11 11.8 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FeoB_N PF02421.18 ORX91965.1 - 0.067 12.7 0.1 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 ORX91965.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 ORX91965.1 - 0.1 12.6 0.1 0.4 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 ORX91965.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 ORX91965.1 - 0.14 11.9 0.5 0.19 11.5 0.4 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system WD40 PF00400.32 ORX91966.1 - 4.8e-25 87.3 2.1 0.00015 22.5 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX91966.1 - 5.4e-08 33.0 0.0 0.13 12.6 0.0 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORX91966.1 - 0.00051 19.9 0.0 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 ORX91966.1 - 0.00084 19.3 1.5 0.0037 17.2 0.1 2.7 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX91966.1 - 0.054 12.8 1.4 0.44 9.8 0.1 2.9 3 1 1 4 4 4 0 WD40-like domain PD40 PF07676.12 ORX91966.1 - 0.16 12.0 0.5 29 4.8 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TnpW PF14202.6 ORX91966.1 - 5.5 6.9 5.8 0.41 10.5 0.2 2.0 2 0 0 2 2 2 0 Transposon-encoded protein TnpW Rad10 PF03834.14 ORX91967.1 - 8.1e-51 170.8 0.2 1.4e-50 170.1 0.1 1.5 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 ORX91967.1 - 8.1e-09 36.0 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ORX91967.1 - 0.00052 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DHHA2 PF02833.14 ORX91967.1 - 0.013 15.6 0.0 1.9 8.7 0.0 2.1 1 1 1 2 2 2 0 DHHA2 domain HHH PF00633.23 ORX91967.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_M32 PF02074.15 ORX91968.1 - 4.7e-174 579.7 0.0 5.4e-174 579.5 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Pkinase PF00069.25 ORX91970.1 - 2.1e-30 106.0 0.0 2.6e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX91970.1 - 3.6e-05 23.2 0.0 4.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX91970.1 - 0.00026 21.0 0.3 0.00048 20.1 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORX91970.1 - 0.00056 19.1 0.4 0.00077 18.6 0.4 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 ORX91970.1 - 0.0017 17.8 0.7 0.0025 17.2 0.7 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX91970.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORX91970.1 - 0.027 14.1 0.7 0.049 13.2 0.7 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 ORX91970.1 - 0.064 12.0 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PI3_PI4_kinase PF00454.27 ORX91970.1 - 0.099 12.4 0.5 0.44 10.3 0.4 1.8 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase RIO1 PF01163.22 ORX91970.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family PNP_UDP_1 PF01048.20 ORX91971.1 - 1.4e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HTH_16 PF12645.7 ORX91972.1 - 0.15 12.1 0.0 0.77 9.8 0.0 2.2 2 1 1 3 3 3 0 Helix-turn-helix domain Abhydrolase_3 PF07859.13 ORX91973.1 - 4.9e-54 183.4 0.0 6.9e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX91973.1 - 9.9e-10 37.9 0.9 3.3e-09 36.2 0.9 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 ORX91973.1 - 1.1e-06 27.8 0.2 1.4e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORX91973.1 - 0.15 11.5 0.0 0.75 9.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Oxidored_FMN PF00724.20 ORX91981.1 - 4.8e-07 29.4 0.0 5.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DLH PF01738.18 ORX91983.1 - 0.00011 21.9 0.4 0.00051 19.7 0.4 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ORX91983.1 - 0.0056 16.6 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ORX91983.1 - 0.029 13.1 0.3 0.12 11.1 0.1 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) SBF2 PF12335.8 ORX91985.1 - 0.024 14.3 0.4 0.027 14.1 0.4 1.0 1 0 0 1 1 1 0 Myotubularin protein Myticin-prepro PF10690.9 ORX91987.1 - 0.013 15.7 0.3 0.021 15.1 0.3 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel FlxA PF14282.6 ORX91990.1 - 0.018 15.0 0.8 0.026 14.5 0.8 1.2 1 0 0 1 1 1 0 FlxA-like protein Metallophos PF00149.28 ORX92007.1 - 6.2e-14 53.0 0.2 1.1e-13 52.2 0.1 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX92007.1 - 0.04 14.1 0.0 0.17 12.1 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GDP_Man_Dehyd PF16363.5 ORX92009.1 - 6e-73 246.1 0.0 7.1e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX92009.1 - 2.8e-57 194.0 0.1 3.5e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX92009.1 - 5.9e-26 91.1 0.0 7.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORX92009.1 - 1.1e-18 67.4 1.0 4.7e-17 62.0 1.0 2.3 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORX92009.1 - 3.1e-17 62.7 0.0 2.9e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORX92009.1 - 2.8e-16 59.5 0.0 3.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORX92009.1 - 1.3e-05 25.1 0.0 3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DAO PF01266.24 ORX92010.1 - 5.5e-41 141.3 0.2 6.9e-41 141.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX92010.1 - 1.3e-05 24.6 0.0 2.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX92010.1 - 2.5e-05 23.6 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORX92010.1 - 3.6e-05 23.9 0.1 0.00012 22.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORX92010.1 - 5.9e-05 23.5 1.3 0.00017 22.0 1.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORX92010.1 - 0.00039 20.1 0.3 0.00082 19.0 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORX92010.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 ORX92010.1 - 0.0025 17.1 0.1 0.0046 16.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX92010.1 - 0.0034 16.5 0.2 0.0058 15.8 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 ORX92010.1 - 0.0043 16.9 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ORX92010.1 - 0.012 14.9 0.2 0.02 14.1 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 ORX92010.1 - 0.012 14.9 0.0 0.065 12.5 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORX92010.1 - 0.042 13.4 1.5 0.085 12.4 1.5 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 ORX92010.1 - 0.061 12.6 0.6 0.12 11.7 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ORX92010.1 - 0.63 9.3 3.7 1.1 8.5 1.9 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX92010.1 - 3.9 6.1 5.9 0.24 10.1 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein GATA PF00320.27 ORX92011.1 - 2.6e-17 62.1 2.4 3.1e-17 61.9 2.4 1.1 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX92011.1 - 0.00085 18.8 0.2 0.0011 18.4 0.2 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX92011.1 - 0.036 14.2 0.4 0.046 13.9 0.4 1.2 1 0 0 1 1 1 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORX92011.1 - 0.091 12.9 1.1 0.12 12.6 1.1 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 ORX92011.1 - 0.2 11.1 3.0 0.74 9.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 ORX92011.1 - 0.5 10.2 3.4 1.8 8.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF4598 PF15370.6 ORX92012.1 - 0.013 16.0 3.1 0.013 16.0 3.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) Myb_DNA-binding PF00249.31 ORX92012.1 - 0.013 15.7 0.4 0.068 13.4 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORX92012.1 - 0.4 10.6 0.1 0.4 10.6 0.1 2.6 2 1 0 3 3 3 0 Myb DNA-binding like SIR4_SID PF16991.5 ORX92012.1 - 8.2 6.5 13.6 0.22 11.6 1.8 2.3 2 0 0 2 2 2 0 Sir4 SID domain Ribosomal_L37e PF01907.19 ORX92013.1 - 1.2e-27 95.9 13.0 1.8e-27 95.2 13.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX92013.1 - 0.0061 16.6 1.6 0.0097 15.9 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORX92013.1 - 0.035 14.1 0.9 0.049 13.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORX92013.1 - 0.21 11.1 3.5 2.2 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORX92013.1 - 0.71 9.8 5.4 1.1 9.1 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 ORX92013.1 - 2.2 7.7 5.2 1.2 8.6 3.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Methyltransf_23 PF13489.6 ORX92014.1 - 1e-08 35.2 0.0 2.4e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX92014.1 - 3.2e-07 31.0 0.0 7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92014.1 - 7.3e-07 29.1 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORX92014.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX92014.1 - 4.5e-05 24.0 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX92014.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORX92014.1 - 0.00014 22.6 0.0 0.00031 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX92014.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ORX92014.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ORX92014.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.11 ORX92014.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Aminotran_4 PF01063.19 ORX92015.1 - 5.7e-19 68.9 0.0 1.1e-18 67.9 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV PXA PF02194.15 ORX92016.1 - 1.7e-45 155.2 0.5 1.7e-45 155.2 0.5 2.4 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 ORX92016.1 - 9.5e-29 100.2 0.9 9.5e-29 100.2 0.9 3.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 ORX92016.1 - 2.4e-18 66.1 1.8 4.9e-18 65.2 0.5 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.19 ORX92016.1 - 4.7e-13 49.4 0.3 4.7e-13 49.4 0.3 2.7 3 0 0 3 3 3 1 Regulator of G protein signaling domain Rbsn PF11464.8 ORX92016.1 - 3e-07 30.1 1.0 8.7e-07 28.6 1.0 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Isy1 PF06246.12 ORX92016.1 - 2.1e-05 24.2 3.8 2.1e-05 24.2 3.8 2.3 2 1 0 2 2 2 1 Isy1-like splicing family OCD_Mu_crystall PF02423.15 ORX92017.1 - 1.1e-65 221.6 0.1 1.5e-65 221.3 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ORX92017.1 - 5.6e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORX92017.1 - 0.0034 17.6 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 ORX92017.1 - 0.0046 17.8 0.0 0.0096 16.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ORX92017.1 - 0.097 13.3 0.0 0.61 10.7 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Med9 PF07544.13 ORX92017.1 - 0.18 11.9 0.7 24 5.1 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DnaJ PF00226.31 ORX92018.1 - 1.5e-25 89.1 0.4 3.5e-25 87.9 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 ORX92018.1 - 2.2e-24 85.8 3.4 4.3e-24 84.8 3.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Hira PF07569.11 ORX92019.1 - 1.4e-55 188.4 0.0 2.6e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 ORX92019.1 - 4.9e-21 74.6 24.2 3.5e-08 34.0 0.9 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92019.1 - 2.5e-12 46.9 0.8 0.0023 18.2 0.0 5.6 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 ORX92019.1 - 4.8e-06 26.3 1.5 4.8e-06 26.3 1.5 2.0 2 0 0 2 2 2 1 HIRA B motif TFIIIC_delta PF12657.7 ORX92019.1 - 0.0015 18.5 4.2 1.2 9.0 0.5 3.9 3 0 0 3 3 3 2 Transcription factor IIIC subunit delta N-term DASH_Dad2 PF08654.10 ORX92019.1 - 0.13 12.6 0.0 0.41 11.1 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 HBS1_N PF08938.10 ORX92019.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 HBS1 N-terminus SH3_9 PF14604.6 ORX92020.1 - 2.5e-11 43.2 0.2 5.1e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX92020.1 - 2.1e-06 27.2 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain fn2 PF00040.19 ORX92020.1 - 2.5e-06 27.6 4.2 7.6e-06 26.1 4.2 1.9 1 0 0 1 1 1 1 Fibronectin type II domain SH3_2 PF07653.17 ORX92020.1 - 3.8e-05 23.3 0.2 7.2e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kringle PF00051.18 ORX92020.1 - 0.043 14.1 1.0 0.098 13.0 1.0 1.6 1 0 0 1 1 1 0 Kringle domain HIG_1_N PF04588.13 ORX92020.1 - 0.13 12.5 1.7 0.3 11.3 1.7 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DUF4366 PF14283.6 ORX92020.1 - 0.15 12.1 0.3 0.34 10.9 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) VSP PF03302.13 ORX92020.1 - 4.3 6.1 14.5 0.35 9.7 8.9 1.8 1 1 0 2 2 2 0 Giardia variant-specific surface protein PseudoU_synth_1 PF01416.20 ORX92021.1 - 1e-11 45.2 0.0 2.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF1647 PF07801.11 ORX92023.1 - 0.00066 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Anemone_cytotox PF06369.12 ORX92023.1 - 0.13 11.9 0.4 0.22 11.2 0.4 1.3 1 0 0 1 1 1 0 Sea anemone cytotoxic protein TLD PF07534.16 ORX92024.1 - 1.7e-25 89.8 0.4 3.9e-25 88.7 0.4 1.6 1 0 0 1 1 1 1 TLD GATA PF00320.27 ORX92025.1 - 5.3e-18 64.3 3.2 6.5e-18 64.0 3.2 1.1 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX92025.1 - 0.0063 16.0 0.1 0.0079 15.7 0.1 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 ORX92025.1 - 0.011 15.1 2.9 0.88 9.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 ORX92025.1 - 0.035 14.2 1.2 0.045 13.9 1.2 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TPR_12 PF13424.6 ORX92026.1 - 1.5e-09 38.0 0.5 6.4e-06 26.4 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92026.1 - 2.9e-08 33.3 0.1 0.00024 21.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX92026.1 - 6.4e-08 32.1 0.0 0.00029 20.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92026.1 - 2.4e-06 27.1 0.0 0.0087 15.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92026.1 - 0.00028 20.7 0.0 0.22 11.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92026.1 - 0.0015 19.0 0.0 0.0057 17.1 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92026.1 - 0.0019 18.7 0.1 0.079 13.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX92026.1 - 0.0053 17.4 0.0 0.17 12.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92026.1 - 0.014 16.1 0.0 2.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX92026.1 - 0.027 14.3 0.0 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 ORX92027.1 - 3.1e-22 78.5 0.1 4.1e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 ORX92027.1 - 0.0022 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 ORX92027.1 - 0.0036 17.7 0.2 0.0059 17.0 0.2 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 ORX92027.1 - 0.0047 17.3 0.0 0.0061 17.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 ORX92027.1 - 0.0048 17.3 0.2 0.0086 16.5 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 ORX92027.1 - 0.025 14.4 0.8 0.22 11.3 0.3 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORX92027.1 - 0.047 13.8 0.7 1.1 9.4 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.6 ORX92027.1 - 0.057 13.7 0.0 0.072 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BetaGal_dom4_5 PF13364.6 ORX92027.1 - 0.061 13.9 0.0 0.086 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Atg14 PF10186.9 ORX92027.1 - 0.071 12.2 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SH3BGR PF04908.15 ORX92027.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein EamA PF00892.20 ORX92028.1 - 7.6e-14 52.0 25.0 1.2e-08 35.3 2.7 2.5 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORX92028.1 - 5e-11 42.3 5.4 6.5e-11 42.0 5.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 ORX92028.1 - 3.9e-09 36.3 12.2 1.1e-08 34.8 12.2 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORX92028.1 - 2.3e-06 27.0 9.7 4.4e-06 26.1 9.7 1.4 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 ORX92028.1 - 2.6e-06 26.7 3.4 2.6e-06 26.7 3.4 2.4 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 ORX92028.1 - 1.3e-05 24.6 3.0 1.3e-05 24.6 3.0 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Bax1-I PF01027.20 ORX92028.1 - 0.00067 19.5 8.0 0.00067 19.5 8.0 2.9 2 1 1 3 3 3 1 Inhibitor of apoptosis-promoting Bax1 DMT_6 PF04342.12 ORX92028.1 - 2.5 8.3 9.1 13 6.0 1.1 2.8 2 1 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Pyr_redox_2 PF07992.14 ORX92029.1 - 9.3e-50 169.5 0.0 1.1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX92029.1 - 5.7e-14 52.4 0.0 2.3e-10 40.9 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX92029.1 - 0.096 11.9 0.2 0.5 9.6 0.2 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.25 ORX92030.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX92030.1 - 2.1e-11 43.8 0.1 2.8e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX92030.1 - 4.9e-11 42.9 0.1 8.2e-11 42.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX92030.1 - 2.7e-07 30.5 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ORX92030.1 - 0.00016 21.9 0.1 0.00029 21.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX92030.1 - 0.0031 17.6 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORX92030.1 - 0.0037 17.0 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ORX92030.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 ORX92030.1 - 0.016 15.4 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_3 PF13302.7 ORX92030.1 - 0.048 14.3 0.0 0.058 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORX92030.1 - 0.072 12.7 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 GNAT acetyltransferase PALP PF00291.25 ORX92031.1 - 6.3e-66 222.8 0.2 8.2e-66 222.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORX92031.1 - 1e-13 51.5 0.2 2.1e-09 37.7 0.0 2.9 2 0 0 2 2 2 2 CBS domain Ion_trans PF00520.31 ORX92032.1 - 2.7e-11 43.2 7.8 3.7e-11 42.7 7.8 1.2 1 0 0 1 1 1 1 Ion transport protein CtIP_N PF10482.9 ORX92032.1 - 0.062 13.4 2.3 0.12 12.4 2.3 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF3742 PF12553.8 ORX92032.1 - 0.19 11.9 4.6 1.5 8.9 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) Metallophos PF00149.28 ORX92033.1 - 1.1e-16 62.0 0.0 2.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX92033.1 - 0.027 14.7 0.0 0.089 13.0 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Arrestin_C PF02752.22 ORX92037.1 - 8.9e-13 48.8 0.2 5.5e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX92037.1 - 2.9e-08 33.9 0.4 2.3e-07 31.0 0.1 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX92037.1 - 0.12 11.6 0.2 2.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Rgp1 OsmC PF02566.19 ORX92038.1 - 2e-15 57.1 0.0 3.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Arrestin_C PF02752.22 ORX92039.1 - 7.6e-10 39.4 0.0 3.8e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX92039.1 - 8.3e-08 32.4 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Polysacc_lyase PF14099.6 ORX92040.1 - 0.00022 21.2 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase DUF4203 PF13886.6 ORX92041.1 - 0.0014 18.4 16.2 0.0014 18.4 16.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Pro_isomerase PF00160.21 ORX92041.1 - 0.06 13.6 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fun_ATP-synt_8 PF05933.13 ORX92041.1 - 0.062 13.5 2.1 0.062 13.5 2.1 2.5 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) GPI-anchored PF10342.9 ORX92042.1 - 7.3e-14 52.3 3.7 1e-13 51.8 0.0 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ctr PF04145.15 ORX92042.1 - 0.027 15.1 0.1 0.037 14.6 0.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Menin PF05053.13 ORX92042.1 - 0.072 11.4 6.4 0.084 11.2 6.4 1.0 1 0 0 1 1 1 0 Menin Mucin PF01456.17 ORX92042.1 - 0.6 10.1 15.9 0.84 9.6 15.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 ORX92042.1 - 2.5 6.2 24.3 3.2 5.8 24.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1180 PF06679.12 ORX92042.1 - 5.8 7.3 11.3 7.7 6.9 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Arrestin_N PF00339.29 ORX92043.1 - 4.4e-09 36.5 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX92043.1 - 5.4e-05 23.7 1.6 0.00038 20.9 1.5 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX92043.1 - 0.0098 15.6 0.0 0.044 13.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like ALO PF04030.14 ORX92044.1 - 3.5e-78 263.0 6.3 5.5e-78 262.4 6.0 1.5 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ORX92044.1 - 1.6e-23 83.0 0.0 3.1e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Arrestin_C PF02752.22 ORX92045.1 - 1.2e-17 64.7 0.1 4.2e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX92045.1 - 2e-12 47.4 0.0 5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX92045.1 - 5.1e-05 23.1 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Vps26 PF03643.15 ORX92045.1 - 0.15 11.0 0.0 0.38 9.7 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 GILT PF03227.16 ORX92046.1 - 3.8e-15 56.1 0.9 3.8e-15 56.1 0.9 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Fe-ADH_2 PF13685.6 ORX92046.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Glyco_hydro_18 PF00704.28 ORX92047.1 - 5.2e-91 305.6 4.2 5.9e-91 305.4 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 APS_kinase PF01583.20 ORX92048.1 - 1.9e-73 245.6 0.0 2.3e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORX92048.1 - 6.3e-10 39.4 0.0 1.5e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX92048.1 - 8.2e-05 23.2 0.0 0.00015 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORX92048.1 - 0.00062 19.3 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 ORX92048.1 - 0.032 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.12 ORX92048.1 - 0.032 14.1 0.2 0.63 9.9 0.2 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 ORX92048.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit 6PF2K PF01591.18 ORX92048.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SAC3_GANP PF03399.16 ORX92049.1 - 6.6e-94 314.6 1.7 1.1e-93 313.9 1.7 1.3 1 1 0 1 1 1 1 SAC3/GANP family Cytochrome_B PF00033.19 ORX92050.1 - 3.4e-37 128.1 7.1 3.8e-37 127.9 7.1 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 ORX92050.1 - 5.2e-27 94.9 6.3 5.8e-27 94.7 6.3 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.20 ORX92050.1 - 0.0089 15.6 3.0 0.012 15.2 3.0 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Hexokinase_2 PF03727.16 ORX92054.1 - 1.5e-81 273.4 0.1 2.4e-81 272.7 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX92054.1 - 1.9e-64 217.3 0.0 2.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF4783 PF16022.5 ORX92054.1 - 0.035 14.3 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) Sugar_tr PF00083.24 ORX92055.1 - 2.8e-98 329.7 30.7 3.4e-98 329.5 30.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX92055.1 - 3.2e-19 69.1 55.3 7.2e-18 64.6 28.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SQHop_cyclase_C PF13243.6 ORX92056.1 - 4.9e-58 196.7 0.1 2.9e-52 177.8 0.1 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORX92056.1 - 1.3e-49 168.9 0.1 1.5e-42 145.7 0.0 3.8 4 1 0 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORX92056.1 - 8.9e-35 118.1 18.9 6e-11 41.9 0.1 6.3 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORX92056.1 - 2.7e-06 26.7 0.2 0.00033 19.8 0.1 2.9 2 2 2 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 ORX92056.1 - 0.0013 18.1 0.7 1.5 8.1 0.0 4.5 5 1 0 5 5 5 1 Pectic acid lyase Mago-bind PF09282.10 ORX92056.1 - 0.0047 16.8 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 Mago binding Phage_lysozyme PF00959.19 ORX92057.1 - 7.5e-13 48.9 0.1 1e-12 48.5 0.1 1.1 1 0 0 1 1 1 1 Phage lysozyme TryThrA_C PF12319.8 ORX92057.1 - 0.016 14.7 1.3 0.046 13.2 0.6 1.9 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Ion_trans_2 PF07885.16 ORX92057.1 - 0.15 12.1 0.1 0.53 10.3 0.0 1.8 2 0 0 2 2 2 0 Ion channel DUF872 PF05915.12 ORX92067.1 - 0.25 11.5 5.5 0.64 10.2 0.1 2.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4381 PF14316.6 ORX92067.1 - 1 9.6 3.3 2.3 8.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) DUF3020 PF11223.8 ORX92069.1 - 6.4e-22 77.8 13.2 6.4e-22 77.8 13.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) VPS13 PF16908.5 ORX92070.1 - 6.4e-79 265.1 9.5 1.8e-76 257.0 0.2 4.9 4 1 1 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 ORX92070.1 - 1.6e-78 263.4 19.8 6.1e-76 254.9 4.2 6.4 5 1 0 5 5 5 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 ORX92070.1 - 1.9e-72 242.8 7.2 1e-67 227.3 0.2 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 ORX92070.1 - 1.6e-61 208.1 0.1 2.6e-58 197.6 0.0 3.1 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 ORX92070.1 - 4.5e-25 88.0 0.2 2.6e-24 85.5 0.2 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORX92070.1 - 4.3e-11 43.0 0.1 1.4e-10 41.4 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain TFIIIC_sub6 PF10419.9 ORX92071.1 - 6.9e-21 73.9 0.4 9.3e-21 73.5 0.4 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Sel1 PF08238.12 ORX92072.1 - 6.6e-20 71.1 7.3 2.5e-07 31.1 0.6 4.6 4 1 0 4 4 4 4 Sel1 repeat TPR_3 PF07720.12 ORX92072.1 - 0.22 11.5 0.4 0.22 11.5 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Gln-synt_N PF03951.19 ORX92079.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain NAGPA PF09992.9 ORX92080.1 - 4.6e-09 36.7 0.1 7.2e-09 36.1 0.1 1.3 1 1 0 1 1 1 1 Phosphodiester glycosidase NAGPA PF09992.9 ORX92082.1 - 8.6e-08 32.6 0.1 9e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 Phosphodiester glycosidase AAA PF00004.29 ORX92083.1 - 3.3e-19 69.6 0.0 4.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORX92083.1 - 4.9e-07 29.6 0.0 1.2e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORX92083.1 - 1.8e-06 28.4 0.0 2.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 ORX92083.1 - 5.6e-05 23.5 0.0 9.4e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 RNA helicase DUF815 PF05673.13 ORX92083.1 - 8.6e-05 21.8 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORX92083.1 - 0.00056 19.5 0.0 0.00075 19.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 ORX92083.1 - 0.00096 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORX92083.1 - 0.0016 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 ORX92083.1 - 0.0033 18.0 0.0 0.005 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX92083.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORX92083.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.5 2 0 0 2 2 1 1 NACHT domain ATPase_2 PF01637.18 ORX92083.1 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 ORX92083.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 ORX92083.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 ORX92083.1 - 0.016 15.7 0.0 0.022 15.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORX92083.1 - 0.02 14.6 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORX92083.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 ORX92083.1 - 0.021 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 ORX92083.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ORX92083.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORX92083.1 - 0.043 13.7 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 ORX92083.1 - 0.063 12.5 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 ORX92083.1 - 0.066 12.4 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORX92083.1 - 0.084 13.2 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX92083.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_3 PF07726.11 ORX92083.1 - 0.096 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORX92083.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ORX92083.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_6 PF12774.7 ORX92083.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Parvo_NS1 PF01057.17 ORX92083.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 T2SSE PF00437.20 ORX92083.1 - 0.13 11.3 0.0 0.5 9.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 ORX92083.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORX92083.1 - 0.18 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX92083.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORX92083.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.6 ORX92083.1 - 0.27 9.8 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain NAGPA PF09992.9 ORX92087.1 - 6.4e-12 46.0 0.0 8.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase PBP3 PF18056.1 ORX92087.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 1 1 0 1 1 1 0 Penicillin Binding Protein 3 Domain EGF_alliinase PF04863.13 ORX92088.1 - 0.03 14.7 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Alliinase EGF-like domain DUF3050 PF11251.8 ORX92088.1 - 0.097 12.3 0.2 8.6 5.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3050) NAGPA PF09992.9 ORX92089.1 - 2.8e-08 34.2 0.7 4e-08 33.7 0.7 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase NAGPA PF09992.9 ORX92090.1 - 7.4e-09 36.0 0.2 1.1e-08 35.4 0.2 1.3 1 0 0 1 1 1 1 Phosphodiester glycosidase Channel_Tsx PF03502.13 ORX92091.1 - 0.075 12.8 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx NAGPA PF09992.9 ORX92092.1 - 2.8e-08 34.2 0.7 4e-08 33.7 0.7 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase NAGPA PF09992.9 ORX92094.1 - 3.7e-08 33.8 0.7 5.4e-08 33.2 0.7 1.2 1 0 0 1 1 1 1 Phosphodiester glycosidase PNP_UDP_1 PF01048.20 ORX92097.1 - 7.8e-35 120.2 0.0 9.3e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily BTB_2 PF02214.22 ORX92098.1 - 6.8e-18 64.8 0.0 1.3e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 ORX92098.1 - 3.9e-15 55.8 0.0 7.5e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 ORX92099.1 - 4.4e-18 65.4 0.0 9.5e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 ORX92099.1 - 9.6e-11 41.7 0.0 2.4e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Mo25 PF08569.11 ORX92100.1 - 7.8e-61 206.2 0.3 8.8e-61 206.1 0.3 1.0 1 0 0 1 1 1 1 Mo25-like RNA_binding PF01877.17 ORX92100.1 - 0.049 13.9 0.2 0.097 12.9 0.1 1.6 1 1 0 1 1 1 0 RNA binding Sel1 PF08238.12 ORX92101.1 - 2.7e-55 183.6 17.6 4.1e-09 36.8 0.0 8.6 9 0 0 9 9 9 7 Sel1 repeat TPR_6 PF13174.6 ORX92101.1 - 0.0006 20.3 6.7 5.5 7.8 0.2 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX92101.1 - 0.0015 18.7 1.5 3.7 7.8 0.1 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORX92101.1 - 0.039 14.6 7.9 0.95 10.2 0.4 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92101.1 - 0.044 14.3 7.2 79 3.9 0.0 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF917 PF06032.12 ORX92101.1 - 0.14 11.0 0.0 0.28 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF917) Hamartin PF04388.12 ORX92101.1 - 0.17 10.5 2.8 0.23 10.1 2.8 1.1 1 0 0 1 1 1 0 Hamartin protein TPR_11 PF13414.6 ORX92101.1 - 0.19 11.4 3.7 1 9.1 0.0 4.0 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 ORX92101.1 - 0.2 11.8 9.0 93 3.5 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92101.1 - 0.97 10.4 11.2 1.3 10.0 0.0 5.5 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92101.1 - 3.9 7.9 7.3 58 4.3 0.1 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 ORX92102.1 - 2.9e-37 127.3 0.0 3.8e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX92102.1 - 3.2e-14 52.9 0.0 3.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORX92102.1 - 8.2e-13 48.0 0.1 1.5e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin NDT80_PhoG PF05224.12 ORX92103.1 - 5.6e-37 127.8 0.0 1.3e-36 126.6 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family tRNA_int_end_N2 PF12928.7 ORX92104.1 - 4.9e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 ORX92104.1 - 5e-05 22.9 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain HTH_33 PF13592.6 ORX92104.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Ribosomal_S30 PF04758.14 ORX92105.1 - 4.1e-29 100.6 9.6 4.4e-29 100.4 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CX9C PF16860.5 ORX92106.1 - 1.8e-06 27.9 1.1 0.019 15.0 0.1 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 ORX92106.1 - 3e-05 24.0 0.1 5.2e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 CHCH domain UPF0203 PF05254.12 ORX92106.1 - 0.0001 22.5 0.3 0.032 14.5 0.1 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 ORX92106.1 - 0.0081 16.2 0.3 0.23 11.5 0.1 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1638 PF07796.11 ORX92106.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) KH_5 PF13184.6 ORX92106.1 - 0.17 12.0 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 NusA-like KH domain Sugar_tr PF00083.24 ORX92107.1 - 4.1e-83 279.7 24.3 4.8e-83 279.5 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX92107.1 - 4.5e-29 101.5 58.6 9.4e-25 87.3 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORX92107.1 - 0.00043 19.0 5.5 0.00043 19.0 5.5 3.5 2 1 2 4 4 4 2 MFS/sugar transport protein IF4E PF01652.18 ORX92108.1 - 3.2e-57 192.8 0.4 3.9e-57 192.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cofilin_ADF PF00241.20 ORX92109.1 - 1.5e-24 86.1 0.0 1.9e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rhodanese PF00581.20 ORX92110.1 - 5.2e-13 49.4 0.0 6.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TatD_DNase PF01026.21 ORX92110.1 - 0.078 12.3 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase AcetylCoA_hyd_C PF13336.6 ORX92111.1 - 2.6e-60 202.8 0.0 4.5e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 ORX92111.1 - 6e-24 85.1 0.0 1.4e-23 83.9 0.0 1.6 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.22 ORX92111.1 - 0.0017 18.3 0.1 0.067 13.1 0.0 2.6 2 0 0 2 2 2 1 DeoR C terminal sensor domain AAA_13 PF13166.6 ORX92112.1 - 0.0049 15.6 6.3 0.0051 15.5 6.3 1.0 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.12 ORX92112.1 - 0.0061 16.6 8.0 0.0062 16.5 6.4 1.8 1 1 1 2 2 2 1 Laminin Domain II KinB_sensor PF16767.5 ORX92112.1 - 0.0094 16.4 2.8 0.013 16.0 2.8 1.3 1 0 0 1 1 1 1 Sensor domain of alginate biosynthesis sensor protein KinB DUF948 PF06103.11 ORX92112.1 - 0.036 14.3 3.6 0.41 10.9 0.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 ORX92112.1 - 0.052 13.8 11.5 0.46 10.8 1.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATLF PF07737.11 ORX92112.1 - 0.063 12.6 8.8 0.035 13.4 3.0 2.0 1 1 1 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain DivIC PF04977.15 ORX92112.1 - 0.075 12.8 8.8 0.6 9.9 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator Med9 PF07544.13 ORX92112.1 - 0.1 12.7 9.0 0.17 12.0 5.5 3.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Jnk-SapK_ap_N PF09744.9 ORX92112.1 - 0.11 12.7 7.8 0.23 11.7 7.8 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FliJ PF02050.16 ORX92112.1 - 0.15 12.3 6.6 2.8 8.2 0.8 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein CCDC-167 PF15188.6 ORX92112.1 - 0.17 12.3 6.7 2 8.8 5.7 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2937 PF11157.8 ORX92112.1 - 0.18 11.5 0.3 0.33 10.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Mod_r PF07200.13 ORX92112.1 - 0.18 11.9 11.2 3.6 7.7 8.4 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Syntaxin_2 PF14523.6 ORX92112.1 - 0.19 12.1 12.4 1.2 9.5 11.9 2.0 1 1 0 1 1 1 0 Syntaxin-like protein TMF_DNA_bd PF12329.8 ORX92112.1 - 0.19 11.8 10.0 0.14 12.1 2.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 ORX92112.1 - 0.2 11.9 7.4 0.24 11.6 7.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family JIP_LZII PF16471.5 ORX92112.1 - 0.23 11.7 0.4 0.23 11.7 0.4 2.6 3 1 0 3 3 2 0 JNK-interacting protein leucine zipper II DHR10 PF18595.1 ORX92112.1 - 0.27 11.3 8.9 0.86 9.7 6.9 2.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 ORX92112.1 - 0.28 11.7 11.8 0.4 11.2 11.3 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Med21 PF11221.8 ORX92112.1 - 0.29 11.4 6.8 0.5 10.6 6.8 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF4806 PF16064.5 ORX92112.1 - 0.49 10.7 3.3 2.1 8.7 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) FAM76 PF16046.5 ORX92112.1 - 0.59 9.4 6.8 0.79 9.0 6.8 1.2 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 ORX92112.1 - 0.65 10.6 6.9 2.6 8.7 0.4 2.8 1 1 1 2 2 2 0 SlyX FapA PF03961.13 ORX92112.1 - 0.75 8.3 6.5 0.84 8.2 6.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF641 PF04859.12 ORX92112.1 - 0.93 9.8 7.2 5.3 7.4 7.2 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 ORX92112.1 - 1.5 9.3 7.9 3.7 8.0 0.2 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 ORX92112.1 - 1.7 7.8 7.1 3.8 6.7 7.1 1.6 1 1 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 ORX92112.1 - 3.3 8.3 10.1 34 5.0 10.1 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 ZapB PF06005.12 ORX92112.1 - 3.7 8.1 10.4 0.67 10.4 5.2 2.4 1 1 2 3 3 3 0 Cell division protein ZapB Allexi_40kDa PF05549.11 ORX92112.1 - 3.9 6.9 6.4 5.1 6.5 5.5 1.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.11 ORX92112.1 - 4.1 8.0 9.5 3 8.5 7.0 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal XhlA PF10779.9 ORX92112.1 - 4.8 7.5 11.3 9.2 6.6 2.6 2.7 1 1 2 3 3 3 0 Haemolysin XhlA BST2 PF16716.5 ORX92112.1 - 5.8 7.6 9.8 1.5 9.4 2.5 2.5 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 Swi5 PF07061.11 ORX92112.1 - 6.9 6.8 9.7 3.8 7.7 3.0 2.8 1 1 2 3 3 3 0 Swi5 DUF4337 PF14235.6 ORX92112.1 - 9.9 6.2 7.5 1.8e+02 2.2 7.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) WD40 PF00400.32 ORX92113.1 - 1.9e-63 208.9 20.8 2.3e-11 44.0 0.3 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92113.1 - 3.6e-19 68.9 0.6 3.6e-08 33.6 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX92113.1 - 7.3e-12 44.7 2.8 0.031 12.9 0.2 6.1 3 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORX92113.1 - 8.4e-06 24.8 1.6 0.39 9.4 0.2 4.1 2 1 2 4 4 4 3 Nup133 N terminal like LisH PF08513.11 ORX92113.1 - 8.7e-06 25.5 0.1 2.3e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 LisH HPS3_N PF14761.6 ORX92113.1 - 0.0053 16.3 0.1 2.7 7.5 0.0 3.2 2 1 0 3 3 3 1 Hermansky-Pudlak syndrome 3 PALB2_WD40 PF16756.5 ORX92113.1 - 0.017 14.1 0.4 5.1 5.9 0.0 2.8 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Pox_A_type_inc PF04508.12 ORX92113.1 - 0.045 13.6 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat JAB PF01398.21 ORX92114.1 - 4.2e-19 68.7 0.0 7.8e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 ORX92114.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CAMSAP_CC1 PF17095.5 ORX92114.1 - 0.2 11.5 1.0 0.39 10.6 1.0 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin SAPS PF04499.15 ORX92115.1 - 6.4e-119 397.9 0.8 1.6e-70 238.3 0.1 3.0 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein Imm70 PF15601.6 ORX92115.1 - 0.12 11.9 0.1 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 70 TPR_2 PF07719.17 ORX92117.1 - 2.1e-27 93.0 8.8 0.00072 19.5 0.0 8.1 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92117.1 - 8.4e-27 91.9 4.6 3.6e-05 23.4 0.0 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat DnaJ PF00226.31 ORX92117.1 - 1.8e-22 79.2 2.7 2.4e-22 78.8 0.5 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 ORX92117.1 - 7e-17 60.8 4.2 8.8e-05 22.1 0.0 6.2 3 3 3 6 6 6 3 TPR repeat TPR_8 PF13181.6 ORX92117.1 - 1.5e-16 59.1 13.4 0.00036 20.5 0.0 8.5 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92117.1 - 2e-15 57.0 3.8 5.7e-05 23.5 0.1 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORX92117.1 - 4.7e-14 52.8 0.3 0.00011 22.8 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX92117.1 - 1.2e-13 51.0 0.0 2.1e-05 24.6 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92117.1 - 1.3e-13 50.5 2.7 0.24 12.3 0.0 6.2 4 2 3 7 7 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92117.1 - 2e-10 40.8 6.0 0.0029 17.9 0.1 5.4 3 3 3 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORX92117.1 - 3e-10 39.7 8.3 4.4e-05 23.6 0.1 6.8 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92117.1 - 2.9e-06 27.5 6.9 4.8 8.0 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORX92117.1 - 9.5e-06 25.9 4.8 0.16 12.3 0.0 5.2 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORX92117.1 - 3.7e-05 23.1 2.4 1 8.5 0.1 4.6 3 1 1 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORX92117.1 - 0.00013 21.3 1.6 4.6 6.8 0.1 5.1 5 0 0 5 5 5 1 SHNi-TPR BTAD PF03704.17 ORX92117.1 - 0.00015 22.2 1.0 1.6 9.1 0.0 3.5 3 1 0 3 3 3 2 Bacterial transcriptional activator domain DUF3856 PF12968.7 ORX92117.1 - 0.00075 19.6 2.1 0.72 9.9 0.0 4.5 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) HemY_N PF07219.13 ORX92117.1 - 0.00093 19.4 3.1 11 6.2 0.0 4.4 5 0 0 5 5 4 0 HemY protein N-terminus ANAPC3 PF12895.7 ORX92117.1 - 0.00093 19.4 7.7 2.2 8.6 0.8 4.5 4 2 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORX92117.1 - 0.0036 17.2 1.3 91 3.4 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.15 ORX92117.1 - 0.022 14.8 4.7 1.3 9.1 0.1 3.4 3 2 0 3 3 2 0 MAS20 protein import receptor MIT PF04212.18 ORX92117.1 - 0.03 14.4 4.5 8 6.6 0.1 4.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 ORX92117.1 - 0.034 14.4 3.1 0.11 12.7 0.0 3.1 3 1 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 DUF357 PF04010.13 ORX92117.1 - 0.71 10.0 6.7 18 5.5 0.2 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF357) HEPN PF05168.14 ORX92117.1 - 7.3 6.8 10.8 24 5.1 0.0 4.9 5 1 1 6 6 6 0 HEPN domain LRR_6 PF13516.6 ORX92118.1 - 4.3e-21 73.1 12.2 0.039 14.0 0.0 11.0 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 ORX92118.1 - 2.8e-15 56.2 3.6 0.01 16.2 0.0 7.1 3 2 5 9 9 9 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORX92118.1 - 7.6e-10 38.5 2.0 1.1e-09 38.0 0.8 1.9 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 ORX92118.1 - 8.5e-09 34.8 2.5 4.1 8.3 0.1 9.6 10 1 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.6 ORX92118.1 - 0.0015 18.2 0.5 14 5.5 0.0 5.6 4 3 1 5 5 5 1 Leucine rich repeat F-box PF00646.33 ORX92118.1 - 0.0015 18.3 1.6 0.02 14.8 0.3 2.7 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 ORX92118.1 - 0.031 14.0 3.7 47 3.7 0.1 5.3 4 2 1 6 6 6 0 Protein of unknown function (DUF1699) POTRA_1 PF08478.10 ORX92118.1 - 0.06 13.7 0.0 2.9 8.3 0.0 2.9 2 0 0 2 2 2 0 POTRA domain, FtsQ-type MCU PF04678.13 ORX92119.1 - 5.5e-38 130.8 0.3 8.6e-38 130.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Peptidase_M22 PF00814.25 ORX92120.1 - 2.5e-86 289.7 0.1 3e-86 289.5 0.1 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 ORX92120.1 - 7.4e-05 22.6 0.1 0.002 17.9 0.0 2.1 1 1 1 2 2 2 1 Carbamoyltransferase N-terminus YycC PF14174.6 ORX92120.1 - 0.28 11.0 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 YycC-like protein Lipase_GDSL_2 PF13472.6 ORX92121.1 - 5.5e-10 39.9 0.0 6.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORX92121.1 - 1.3e-08 35.0 0.0 1.6e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ORX92121.1 - 0.03 14.5 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family APC_u9 PF16633.5 ORX92121.1 - 0.052 14.6 0.1 0.2 12.8 0.0 1.8 1 1 1 2 2 2 0 Unstructured region on APC between 1st two creatine-rich regions Activator_LAG-3 PF11498.8 ORX92121.1 - 0.24 10.3 0.0 0.34 9.8 0.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Glyco_tranf_2_3 PF13641.6 ORX92122.1 - 1.5e-30 106.8 0.0 2e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX92122.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX92122.1 - 5.3e-10 39.0 0.0 1.7e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 ORX92122.1 - 1.3e-05 25.3 1.1 1.3e-05 25.3 1.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 ORX92122.1 - 0.0023 16.6 2.7 0.0024 16.6 0.1 2.1 2 1 0 2 2 2 1 Chitin synthase Dynamitin PF04912.14 ORX92123.1 - 1.3e-39 136.6 44.1 2.1e-39 136.0 38.2 2.0 1 1 1 2 2 2 1 Dynamitin DASH_Hsk3 PF08227.11 ORX92123.1 - 0.013 15.8 3.6 0.013 15.8 3.6 5.8 4 1 3 7 7 6 0 DASH complex subunit Hsk3 like DHDPS PF00701.22 ORX92123.1 - 0.014 14.1 0.1 0.031 13.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family KELK PF15796.5 ORX92123.1 - 0.02 15.4 4.2 0.02 15.4 4.2 4.4 4 1 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CREPT PF16566.5 ORX92123.1 - 0.021 15.0 7.9 0.021 15.0 7.9 3.9 2 1 1 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 ORX92123.1 - 0.038 14.0 22.4 0.23 11.5 1.0 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) T2SSF PF00482.23 ORX92123.1 - 0.068 13.1 2.1 10 6.1 0.0 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F aGPT-Pplase3 PF18746.1 ORX92123.1 - 0.11 11.8 2.4 0.55 9.5 0.3 2.3 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Fib_alpha PF08702.10 ORX92123.1 - 0.4 10.9 35.7 0.36 11.0 7.0 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family CLZ PF16526.5 ORX92123.1 - 0.65 10.4 26.8 0.55 10.6 4.5 5.7 4 3 2 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels IKKbetaNEMObind PF12179.8 ORX92123.1 - 0.65 10.1 7.4 17 5.6 0.4 4.0 2 1 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Occludin_ELL PF07303.13 ORX92123.1 - 0.75 10.6 16.7 6.5 7.5 0.1 3.7 3 1 0 3 3 3 0 Occludin homology domain Prominin PF05478.11 ORX92123.1 - 1 7.2 29.5 1.4 6.7 15.8 2.1 1 1 1 2 2 2 0 Prominin Filament PF00038.21 ORX92123.1 - 1.3 8.5 31.8 0.11 12.0 5.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein DUF1515 PF07439.11 ORX92123.1 - 1.4 9.0 11.3 0.78 9.8 0.4 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) DUF1512 PF07431.12 ORX92123.1 - 2.1 7.2 7.6 0.38 9.7 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1512) Seryl_tRNA_N PF02403.22 ORX92123.1 - 3.4 8.0 25.4 0.35 11.1 4.8 4.1 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 ORX92123.1 - 4 7.6 19.4 3.4 7.9 3.5 4.4 3 1 1 4 4 4 0 MbeD/MobD like Lectin_N PF03954.14 ORX92123.1 - 5.8 6.7 34.7 0.067 12.9 5.9 3.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Jnk-SapK_ap_N PF09744.9 ORX92123.1 - 7.5 6.8 36.8 67 3.7 12.0 3.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 ORX92123.1 - 9.6 4.6 11.5 2.9 6.3 0.9 2.3 1 1 0 2 2 2 0 Fusaric acid resistance protein family Zn_clus PF00172.18 ORX92124.1 - 7.8e-06 25.9 9.3 1.5e-05 25.0 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORX92124.1 - 0.028 14.4 0.1 0.16 12.0 0.0 2.2 3 0 0 3 3 3 0 PAS fold DUF1279 PF06916.13 ORX92125.1 - 8.7e-21 74.3 0.1 1.2e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Oxysterol_BP PF01237.18 ORX92126.1 - 1.2e-85 287.7 0.1 9.2e-84 281.4 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Reprolysin_4 PF13583.6 ORX92127.1 - 1.9e-42 145.2 0.1 3e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORX92127.1 - 2e-41 142.3 4.0 4.6e-41 141.1 4.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORX92127.1 - 4.4e-38 131.1 0.8 4.4e-38 131.1 0.8 2.0 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ORX92127.1 - 1.4e-15 57.8 29.5 1.4e-15 57.8 29.5 5.2 4 2 1 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 ORX92127.1 - 9.1e-14 52.0 0.0 3.4e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 ORX92127.1 - 5.1e-06 26.5 11.0 6.8e-05 22.9 11.0 2.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Cation_ATPase_C PF00689.21 ORX92128.1 - 9.1e-45 152.6 9.9 9.1e-45 152.6 9.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORX92128.1 - 2.3e-40 138.1 2.5 2.3e-40 138.1 2.5 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORX92128.1 - 6.6e-25 87.0 0.0 1.4e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX92128.1 - 1.1e-17 65.0 1.9 2.4e-17 63.9 1.9 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92128.1 - 1.4e-10 40.7 0.1 1e-09 38.0 0.1 2.3 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92128.1 - 0.012 15.3 4.9 0.018 14.8 0.4 2.9 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 ORX92128.1 - 0.039 14.3 3.7 0.11 12.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) MBF1 PF08523.10 ORX92129.1 - 1.3e-21 76.8 3.1 1.3e-21 76.8 3.1 2.2 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 ORX92129.1 - 1.2e-10 41.3 0.3 2e-10 40.6 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ORX92129.1 - 1.5e-06 28.4 0.0 3.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ORX92129.1 - 8.8e-05 22.4 0.3 0.00013 21.9 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sulfotransfer_4 PF17784.1 ORX92130.1 - 1.7e-65 220.9 0.1 2e-65 220.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORX92130.1 - 6.6e-08 33.2 0.9 1.9e-05 25.1 0.1 2.5 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORX92130.1 - 0.059 12.8 0.2 0.15 11.5 0.2 1.9 1 1 0 1 1 1 0 Sulfotransferase domain Glycos_transf_1 PF00534.20 ORX92131.1 - 2.6e-13 49.9 0.1 3.6e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX92131.1 - 2.5e-12 47.4 0.1 2.6e-11 44.1 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORX92131.1 - 0.11 12.9 0.1 5.4 7.5 0.2 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 AMP-binding PF00501.28 ORX92132.1 - 0 1834.6 0.0 2.2e-94 316.4 0.0 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 ORX92132.1 - 0 1392.6 0.4 1.9e-54 185.1 0.0 10.1 10 0 0 10 10 10 9 Condensation domain PP-binding PF00550.25 ORX92132.1 - 6.4e-79 260.3 0.1 3.3e-11 43.4 0.0 7.2 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX92132.1 - 3.1e-43 146.6 0.0 6.4e-09 36.7 0.1 6.9 6 0 0 6 6 6 6 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 ORX92132.1 - 1.7e-25 90.5 0.0 3.9e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Hormone_3 PF00159.18 ORX92132.1 - 0.0082 16.2 0.1 11 6.2 0.0 3.4 3 0 0 3 3 3 2 Pancreatic hormone peptide DEP PF00610.21 ORX92132.1 - 0.0098 15.9 0.0 69 3.6 0.0 3.7 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MukB_hinge PF16330.5 ORX92132.1 - 0.04 13.6 0.1 73 3.0 0.0 5.3 7 0 0 7 7 7 0 MukB hinge domain Abhydrolase_6 PF12697.7 ORX92132.1 - 0.053 14.1 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family YcgR PF07317.12 ORX92132.1 - 0.087 12.7 0.1 2e+02 1.9 0.0 4.6 5 0 0 5 5 5 0 Flagellar regulator YcgR DUF5122 PF17164.4 ORX92132.1 - 2.5 8.5 7.0 1.5e+02 2.8 0.0 5.2 6 0 0 6 6 5 0 Domain of unknown function (DUF5122) beta-propeller ATP-synt_C PF00137.21 ORX92133.1 - 1.2e-28 99.2 32.0 2e-18 66.5 11.4 2.6 2 1 1 3 3 3 2 ATP synthase subunit C SH PF01445.17 ORX92133.1 - 0.21 11.6 0.3 0.21 11.6 0.3 2.0 2 0 0 2 2 2 0 Viral small hydrophobic protein NTF2 PF02136.20 ORX92134.1 - 2.5e-30 105.5 0.1 5.5e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORX92134.1 - 2.6e-10 40.0 0.2 4.4e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORX92134.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif DUF4518 PF15008.6 ORX92134.1 - 0.053 12.7 0.0 0.053 12.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4518) PTS_2-RNA PF01885.16 ORX92135.1 - 4e-68 229.0 0.1 4.8e-68 228.8 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PSI PF01437.25 ORX92138.1 - 0.0015 19.1 11.0 0.0023 18.4 11.0 1.4 1 0 0 1 1 1 1 Plexin repeat Suc_Fer-like PF06999.12 ORX92139.1 - 1e-53 182.1 0.1 1.2e-53 181.9 0.1 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SIS PF01380.22 ORX92141.1 - 4.6e-68 227.1 0.1 2.5e-37 127.6 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORX92141.1 - 9.5e-17 61.5 0.0 3.1e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORX92141.1 - 4.5e-13 49.2 0.0 9.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORX92141.1 - 0.00053 19.0 0.0 0.00086 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORX92141.1 - 0.015 15.3 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 SIS domain GATase_2 PF00310.21 ORX92141.1 - 0.064 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II LPMO_10 PF03067.15 ORX92142.1 - 5.5e-11 43.5 0.5 1.5e-10 42.1 0.1 1.7 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX92142.1 - 0.0096 15.9 0.1 0.029 14.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ribosomal_L29 PF00831.23 ORX92143.1 - 8.5e-21 73.7 3.8 8.5e-21 73.7 3.8 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 ORX92143.1 - 0.075 13.1 1.7 0.075 13.1 1.7 2.3 2 1 0 2 2 2 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 ORX92143.1 - 0.15 12.5 8.9 0.041 14.3 3.6 2.0 1 1 1 2 2 2 0 Snapin/Pallidin PilJ PF13675.6 ORX92143.1 - 0.15 12.1 2.8 0.15 12.1 1.2 1.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prefoldin PF02996.17 ORX92143.1 - 1.4 8.8 8.8 1.1 9.1 2.4 2.8 2 1 1 3 3 3 0 Prefoldin subunit zf-C3HC4_3 PF13920.6 ORX92144.1 - 5.5e-10 38.9 7.9 1e-09 38.1 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX92144.1 - 2.3e-08 33.7 11.2 3.7e-08 33.1 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX92144.1 - 9.7e-08 32.2 10.8 9.7e-08 32.2 10.8 1.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX92144.1 - 9.8e-08 31.7 11.7 1.8e-07 30.9 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX92144.1 - 1.1e-07 31.7 10.2 1.9e-07 30.9 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORX92144.1 - 1.8e-06 27.7 9.2 3.2e-06 26.9 9.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORX92144.1 - 1.2e-05 25.2 9.6 4.8e-05 23.3 5.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORX92144.1 - 8.6e-05 22.6 9.9 0.00018 21.6 9.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORX92144.1 - 0.00012 22.3 5.7 0.00022 21.4 5.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORX92144.1 - 0.0018 18.1 2.4 0.0032 17.3 2.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORX92144.1 - 0.01 15.6 6.3 0.01 15.6 6.3 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 ORX92144.1 - 0.024 14.7 2.9 0.038 14.0 2.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2256 PF10013.9 ORX92144.1 - 0.028 14.5 0.8 0.07 13.3 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_10 PF16685.5 ORX92144.1 - 0.041 14.0 5.4 0.076 13.2 5.4 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 ORX92144.1 - 0.18 11.6 8.2 0.18 11.6 4.7 2.6 3 0 0 3 3 3 0 RING-like zinc finger zf-Nse PF11789.8 ORX92144.1 - 0.26 11.2 5.4 0.68 9.8 5.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 ORX92144.1 - 0.63 9.8 6.5 1.2 8.9 6.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger Gin PF10764.9 ORX92144.1 - 3.9 7.5 10.2 0.29 11.1 3.7 2.3 3 0 0 3 3 2 0 Inhibitor of sigma-G Gin RasGEF PF00617.19 ORX92146.1 - 2.1e-44 151.8 0.0 3.8e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORX92146.1 - 4.4e-10 39.7 3.2 3.6e-09 36.8 0.7 3.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Rota_NS26 PF01525.16 ORX92146.1 - 1.2 9.1 4.8 0.24 11.4 0.4 1.9 2 0 0 2 2 2 0 Rotavirus NS26 DDE_Tnp_1_7 PF13843.6 ORX92148.1 - 0.0005 19.5 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Glyco_hydro_20 PF00728.22 ORX92152.1 - 1.8e-91 307.2 3.3 2.4e-91 306.8 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORX92152.1 - 5.1e-19 69.3 0.0 1.3e-18 68.0 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORX92152.1 - 0.00068 20.4 0.0 0.0037 18.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF727 PF05303.12 ORX92153.1 - 0.00024 21.1 0.1 0.00053 20.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) E1-E2_ATPase PF00122.20 ORX92154.1 - 1.1e-34 119.5 0.3 3.4e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 ORX92154.1 - 9.6e-24 83.9 2.2 3.5e-23 82.1 2.2 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 ORX92154.1 - 1.9e-12 47.9 0.0 0.002 18.4 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX92154.1 - 2e-07 30.9 6.7 2e-07 30.9 6.7 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX92154.1 - 3.2e-05 23.9 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX92154.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ribosomal_S9 PF00380.19 ORX92155.1 - 3.7e-34 117.8 0.2 4.2e-34 117.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Cpn60_TCP1 PF00118.24 ORX92156.1 - 6.9e-158 526.3 3.3 7.8e-158 526.1 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ABC2_membrane_3 PF12698.7 ORX92156.1 - 0.23 10.5 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PPR_2 PF13041.6 ORX92157.1 - 5.6e-117 381.8 25.7 1.1e-16 60.8 0.4 11.2 2 1 10 12 12 12 10 PPR repeat family PPR_3 PF13812.6 ORX92157.1 - 1.1e-78 259.2 27.7 1.5e-11 44.2 0.2 6.4 2 1 7 9 9 9 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX92157.1 - 5e-77 253.3 4.1 3.5e-10 39.4 0.0 10.9 11 1 0 11 11 11 10 PPR repeat PPR PF01535.20 ORX92157.1 - 5.3e-66 214.4 14.7 9.4e-08 31.8 0.0 11.8 11 1 0 11 11 11 10 PPR repeat PPR_long PF17177.4 ORX92157.1 - 3.1e-46 157.4 9.4 2.2e-15 56.6 0.9 4.2 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX92157.1 - 4.1e-12 46.6 11.3 0.026 14.9 0.1 7.1 1 1 5 6 6 6 3 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORX92157.1 - 4.3e-10 39.5 1.8 12 7.1 0.0 9.3 5 3 4 9 9 9 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX92157.1 - 6.3e-10 38.5 8.8 0.00096 18.1 0.2 5.1 1 1 3 6 6 6 3 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 ORX92157.1 - 1.1e-08 35.5 1.1 2.3 8.8 0.0 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92157.1 - 7.9e-06 25.5 0.0 41 4.5 0.0 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat PPP1R35_C PF15503.6 ORX92157.1 - 0.0011 18.8 0.5 0.16 11.8 0.0 3.7 2 1 0 4 4 4 1 Protein phosphatase 1 regulatory subunit 35 C-terminus ECSIT PF06239.11 ORX92157.1 - 0.01 15.0 11.8 0.23 10.6 0.1 5.5 1 1 4 6 6 6 0 Evolutionarily conserved signalling intermediate in Toll pathway AbiEi_2 PF09952.9 ORX92157.1 - 0.015 15.5 1.1 0.059 13.6 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system TetR_C_19 PF17924.1 ORX92157.1 - 0.082 13.5 3.5 2.2 8.9 0.0 4.5 6 1 0 6 6 5 0 Tetracyclin repressor-like, C-terminal domain Rib_hydrolayse PF02267.17 ORX92157.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosyl cyclase V-SNARE_C PF12352.8 ORX92158.1 - 1.7e-14 53.9 4.9 5e-14 52.3 3.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 ORX92158.1 - 8e-14 51.8 2.3 1.2e-13 51.2 1.1 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus FapA PF03961.13 ORX92158.1 - 0.016 13.8 0.1 0.021 13.4 0.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 ORX92158.1 - 0.084 10.8 0.4 0.091 10.7 0.4 1.2 1 0 0 1 1 1 0 Prominin HR1 PF02185.16 ORX92158.1 - 0.5 10.5 8.5 0.14 12.3 5.2 1.9 2 0 0 2 2 2 0 Hr1 repeat Plasmid_RAQPRD PF09686.10 ORX92158.1 - 1.9 8.8 7.9 0.11 12.7 0.8 2.5 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF2315 PF10231.9 ORX92159.1 - 2.6e-35 121.2 2.1 4e-35 120.6 2.1 1.2 1 0 0 1 1 1 1 Apoptogenic protein 1 DHHC PF01529.20 ORX92160.1 - 1.1e-34 119.4 12.0 1.1e-34 119.4 12.0 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase SNAPc_SNAP43 PF09808.9 ORX92161.1 - 2.7e-37 128.6 0.1 4e-37 128.0 0.1 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 O-FucT PF10250.9 ORX92162.1 - 1.9e-18 67.3 0.0 5.9e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aminotran_1_2 PF00155.21 ORX92163.1 - 1.4e-39 136.3 0.0 1.9e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX92163.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L1 PF00687.21 ORX92164.1 - 1.9e-47 161.7 1.5 2.3e-47 161.4 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mod_r PF07200.13 ORX92164.1 - 0.034 14.2 1.4 0.091 12.9 0.2 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TFIIS_C PF01096.18 ORX92165.1 - 6.7e-19 67.5 6.3 6.7e-19 67.5 6.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORX92165.1 - 1.2e-09 37.9 1.3 1.2e-09 37.9 1.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 ORX92165.1 - 0.00075 19.4 9.1 0.018 15.0 3.1 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORX92165.1 - 0.023 14.7 0.3 0.023 14.7 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbons PH_10 PF15411.6 ORX92165.1 - 0.06 13.6 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain zf-TFIIB PF13453.6 ORX92165.1 - 0.065 12.6 3.9 0.93 8.9 1.0 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Auto_anti-p27 PF06677.12 ORX92165.1 - 0.75 10.0 5.2 3.4 7.9 0.6 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Baculo_LEF5_C PF11792.8 ORX92165.1 - 3.6 7.4 7.9 0.73 9.6 2.6 2.4 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Presenilin PF01080.17 ORX92166.1 - 5.6e-119 397.5 0.7 7.9e-119 397.0 0.7 1.2 1 0 0 1 1 1 1 Presenilin zf-MYND PF01753.18 ORX92166.1 - 3.5e-09 36.6 11.7 5.2e-09 36.0 11.7 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORX92166.1 - 0.022 14.9 5.3 0.041 14.0 5.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 ORX92166.1 - 0.12 12.2 8.8 0.23 11.4 8.8 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 ORX92166.1 - 7.5 6.9 10.1 14 6.0 10.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Aa_trans PF01490.18 ORX92168.1 - 5.6e-81 272.3 38.3 6.4e-81 272.1 38.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX92168.1 - 5.8e-05 22.3 13.7 5.8e-05 22.3 13.7 2.9 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3278 PF11683.8 ORX92168.1 - 0.023 14.8 1.2 0.023 14.8 1.2 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3278) GATA PF00320.27 ORX92179.1 - 8.6e-30 102.1 17.2 1.6e-16 59.6 4.5 2.3 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORX92179.1 - 4.3e-06 26.1 2.9 0.016 14.7 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX92179.1 - 0.00077 19.5 4.1 0.42 10.8 0.3 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORX92179.1 - 0.0029 17.7 7.0 0.079 13.1 0.5 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CUT PF02376.15 ORX92179.1 - 0.044 13.9 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 CUT domain OrfB_Zn_ribbon PF07282.11 ORX92179.1 - 0.045 13.7 7.3 1.8 8.5 0.7 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF2387 PF09526.10 ORX92179.1 - 0.07 13.3 3.0 0.7 10.1 0.3 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) TDP43_N PF18694.1 ORX92179.1 - 0.098 12.5 0.1 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 ORX92179.1 - 0.1 12.5 6.8 1.1 9.1 1.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NMD3 PF04981.13 ORX92179.1 - 0.21 11.0 5.8 0.97 8.8 0.2 2.2 1 1 1 2 2 2 0 NMD3 family OTT_1508_deam PF14441.6 ORX92179.1 - 0.33 11.0 4.1 3.5 7.7 0.4 2.7 2 1 0 2 2 2 0 OTT_1508-like deaminase Tnp_zf-ribbon_2 PF13842.6 ORX92179.1 - 1.4 9.8 11.0 0.96 10.3 2.5 3.1 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon FAM60A PF15396.6 ORX92179.1 - 1.6 8.7 11.5 22 4.9 1.9 2.9 1 1 1 2 2 2 0 Protein Family FAM60A FYVE PF01363.21 ORX92179.1 - 1.6 8.9 9.1 1.4 9.1 0.5 2.6 2 1 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 ORX92179.1 - 4.1 7.5 14.0 13 5.9 3.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 ORX92179.1 - 6.6 6.9 7.8 0.94 9.6 0.7 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.12 ORX92179.1 - 7.6 6.9 6.2 27 5.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase CPSase_L_D2 PF02786.17 ORX92180.1 - 2.1e-79 265.9 0.1 3.7e-79 265.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORX92180.1 - 1.1e-70 237.4 0.0 1.8e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORX92180.1 - 1e-36 125.8 0.1 2.3e-36 124.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 ORX92180.1 - 1e-31 110.5 0.0 2.1e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.19 ORX92180.1 - 4.4e-31 107.2 0.0 1.2e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORX92180.1 - 1.5e-18 66.3 5.1 1.7e-17 63.0 2.6 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORX92180.1 - 1.1e-09 38.1 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORX92180.1 - 8.6e-08 31.9 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORX92180.1 - 9.4e-08 31.8 0.3 0.0004 20.2 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 ORX92180.1 - 8.2e-06 26.5 2.8 0.18 12.5 0.0 3.8 4 0 0 4 4 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 ORX92180.1 - 0.0017 18.5 0.0 0.005 16.9 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ORX92180.1 - 0.0032 17.1 0.0 0.075 12.6 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 ORX92180.1 - 0.011 15.0 0.3 0.66 9.1 0.0 2.8 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 ORX92180.1 - 0.034 14.0 0.5 0.39 10.6 0.2 2.7 2 0 0 2 2 2 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 ORX92180.1 - 0.035 13.3 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 ORX92180.1 - 0.13 12.2 0.4 0.47 10.5 0.4 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Gp_dh_C PF02800.20 ORX92181.1 - 1.3e-71 239.3 0.0 1.9e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORX92181.1 - 3.2e-40 136.6 0.1 6.1e-40 135.6 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX92181.1 - 0.0093 16.1 0.1 0.075 13.2 0.0 2.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Chitin_synth_2 PF03142.15 ORX92182.1 - 8.9e-253 839.7 0.0 1.3e-252 839.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX92182.1 - 2e-13 50.8 0.0 4.7e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX92182.1 - 5.1e-13 49.4 5.6 5.1e-13 49.4 5.6 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX92182.1 - 0.013 15.4 0.0 0.67 9.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX92182.1 - 0.023 14.2 0.0 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Gpr1_Fun34_YaaH PF01184.19 ORX92196.1 - 7e-49 166.2 19.9 9e-49 165.9 19.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ysc84 PF04366.12 ORX92197.1 - 7e-45 151.9 0.6 1.5e-44 150.9 0.6 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORX92197.1 - 9.1e-16 57.2 0.3 2.3e-15 55.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORX92197.1 - 2e-12 46.8 0.1 3.4e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX92197.1 - 9e-10 38.1 0.0 2.8e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 ORX92197.1 - 0.082 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) AMPK1_CBM PF16561.5 ORX92198.1 - 1.1e-31 108.9 0.0 1.8e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 ORX92198.1 - 2.5e-22 78.9 1.7 8.5e-22 77.2 0.2 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 ORX92198.1 - 0.014 16.0 0.1 0.029 14.9 0.1 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 ORX92198.1 - 0.02 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) WD40 PF00400.32 ORX92199.1 - 8.9e-51 168.8 22.2 1.1e-07 32.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92199.1 - 8.4e-13 48.4 1.4 0.0072 16.6 0.0 4.9 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX92199.1 - 2.1e-06 27.0 0.4 0.03 13.3 0.1 4.0 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORX92199.1 - 8.4e-06 25.8 0.1 3.7e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORX92199.1 - 0.00055 18.6 0.1 1 7.8 0.0 2.8 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 ORX92199.1 - 0.00067 18.4 6.5 0.068 11.8 0.1 4.7 4 2 0 5 5 5 1 Nucleoporin Nup120/160 PD40 PF07676.12 ORX92199.1 - 0.097 12.6 3.1 38 4.4 0.1 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Choline_transpo PF04515.12 ORX92200.1 - 5.7e-80 269.0 25.2 5.7e-80 269.0 25.2 2.5 2 1 0 3 3 3 1 Plasma-membrane choline transporter DcpS_C PF11969.8 ORX92201.1 - 4.7e-17 62.5 0.0 5.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORX92201.1 - 9.8e-08 32.6 0.1 1.5e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 ORX92201.1 - 0.0067 16.3 0.2 0.01 15.7 0.2 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 LRR_8 PF13855.6 ORX92202.1 - 4e-44 148.2 66.1 4.1e-11 42.5 6.4 6.3 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 ORX92202.1 - 1.3e-32 111.2 47.0 1.5e-06 28.4 4.3 8.6 6 2 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX92202.1 - 3.6e-06 26.6 27.8 0.013 15.0 3.4 4.5 1 1 3 5 5 5 5 Leucine-rich repeat LRR_5 PF13306.6 ORX92202.1 - 8.6e-05 22.5 5.8 0.0032 17.4 2.0 2.5 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 ORX92202.1 - 0.00016 21.7 44.2 6.2 7.8 0.4 12.5 14 1 0 14 14 14 4 Leucine Rich Repeat GHMP_kinases_N PF00288.26 ORX92203.1 - 7.4e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX92203.1 - 0.00073 19.9 0.2 0.0017 18.7 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transf_3 PF12804.7 ORX92203.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain PDEase_I PF00233.19 ORX92204.1 - 1.4e-67 227.9 4.0 2.3e-67 227.2 4.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 ORX92204.1 - 0.00013 22.1 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HD PF01966.22 ORX92204.1 - 0.0034 17.6 0.0 0.017 15.4 0.0 2.0 1 1 1 2 2 2 1 HD domain SPRY PF00622.28 ORX92205.1 - 1.5e-15 57.4 0.4 2.7e-15 56.5 0.4 1.4 1 0 0 1 1 1 1 SPRY domain Kelch_3 PF13415.6 ORX92206.1 - 0.84 10.0 0.0 0.84 10.0 0.0 3.8 5 0 0 5 5 5 0 Galactose oxidase, central domain DUF4641 PF15483.6 ORX92207.1 - 0.22 10.6 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Cadherin_C_2 PF16492.5 ORX92208.1 - 0.13 13.0 0.0 0.58 10.9 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Peptidase_M16 PF00675.20 ORX92209.1 - 4.3e-23 82.0 0.3 9.1e-23 80.9 0.3 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORX92209.1 - 2.2e-19 70.2 0.1 3.6e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain CSTF2_hinge PF14327.6 ORX92209.1 - 0.046 14.2 0.2 16 6.0 0.1 2.7 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 SAP30_Sin3_bdg PF13867.6 ORX92209.1 - 0.082 13.3 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 M16C_assoc PF08367.11 ORX92209.1 - 3.7 6.6 6.8 2.1 7.4 0.0 3.3 4 0 0 4 4 4 0 Peptidase M16C associated SGS PF05002.15 ORX92211.1 - 1e-33 115.3 1.4 7.2e-33 112.5 1.3 2.4 2 0 0 2 2 2 1 SGS domain CS PF04969.16 ORX92211.1 - 2.6e-15 57.2 1.0 5.2e-15 56.2 1.0 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 ORX92211.1 - 9.8e-07 28.4 0.6 0.0032 17.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92211.1 - 0.00015 21.4 3.6 0.00034 20.3 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92211.1 - 0.0007 19.6 0.8 0.033 14.4 0.0 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92211.1 - 0.0054 17.3 0.3 0.21 12.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92211.1 - 0.0096 16.7 0.0 11 7.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92211.1 - 0.043 14.3 0.1 1.5 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92211.1 - 0.082 13.2 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX92211.1 - 4.7 7.0 4.7 1.9 8.2 0.1 2.6 3 0 0 3 3 3 0 TPR repeat Pyr_redox_2 PF07992.14 ORX92212.1 - 6.3e-67 225.9 3.3 6.3e-67 225.9 3.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX92212.1 - 5.5e-34 116.7 0.7 1.3e-33 115.5 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORX92212.1 - 5.9e-21 74.8 6.4 5.8e-18 65.2 0.4 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX92212.1 - 4.1e-17 62.4 2.1 8.7e-17 61.3 2.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX92212.1 - 3.8e-07 29.8 2.0 4.7e-07 29.5 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ORX92212.1 - 7.6e-07 28.5 3.1 1.9e-05 23.9 1.1 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORX92212.1 - 2.1e-06 26.7 6.8 5e-05 22.2 0.4 3.5 3 1 1 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 ORX92212.1 - 6.1e-06 25.6 0.1 0.00059 19.1 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORX92212.1 - 1.5e-05 25.2 2.8 1.8e-05 24.9 0.9 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORX92212.1 - 2.8e-05 23.5 0.5 0.077 12.3 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORX92212.1 - 2.8e-05 23.4 2.1 2.8e-05 23.4 2.1 2.4 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 ORX92212.1 - 6.6e-05 22.3 1.4 0.11 11.8 0.0 3.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 ORX92212.1 - 0.00012 21.8 2.7 0.00012 21.8 2.7 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ORX92212.1 - 0.00056 20.3 0.6 0.54 10.7 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 ORX92212.1 - 0.0017 17.6 0.1 0.0041 16.4 0.1 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 ORX92212.1 - 0.0029 17.6 0.4 0.65 10.0 0.0 2.8 2 1 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ORX92212.1 - 0.0051 16.7 6.4 0.0074 16.2 0.1 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 ORX92212.1 - 0.03 14.1 0.3 3.4 7.5 0.2 2.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein FAD_binding_3 PF01494.19 ORX92212.1 - 0.033 13.4 0.9 1.6 7.9 0.4 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX92212.1 - 0.045 13.7 0.5 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 ORX92212.1 - 0.064 13.8 0.0 6.5 7.3 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 ORX92212.1 - 0.098 11.7 0.5 0.25 10.3 0.4 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 ORX92212.1 - 0.66 9.5 4.5 0.33 10.5 0.5 2.4 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SAM_2 PF07647.17 ORX92213.1 - 1.7e-08 34.4 0.1 1.3e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORX92213.1 - 3.6e-06 27.3 0.2 1e-05 25.9 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IGR PF09597.10 ORX92213.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif Sec2p PF06428.11 ORX92214.1 - 2.1e-14 53.3 9.7 2.1e-14 53.3 9.7 2.6 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p CENP-F_leu_zip PF10473.9 ORX92214.1 - 0.0032 17.5 11.2 0.0032 17.5 11.2 2.6 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3496 PF12001.8 ORX92214.1 - 0.34 11.3 11.6 2.2 8.7 4.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Filament PF00038.21 ORX92214.1 - 0.44 10.1 19.0 0.36 10.4 8.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF4472 PF14739.6 ORX92214.1 - 0.74 10.6 16.4 0.05 14.3 2.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) V_ATPase_I PF01496.19 ORX92214.1 - 1.4 6.7 4.3 2.2 6.1 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.9 ORX92214.1 - 4.8 7.5 9.7 0.59 10.4 2.8 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein RNase_H PF00075.24 ORX92216.1 - 2.3e-44 151.0 0.0 2.9e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 ORX92216.1 - 6.5e-06 26.3 0.1 1.5e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 ORX92216.1 - 0.022 14.6 0.0 0.19 11.5 0.0 2.1 1 1 0 1 1 1 0 Reverse transcriptase-like zf-C2H2 PF00096.26 ORX92217.1 - 4.2e-13 49.0 6.1 2.1e-06 27.9 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX92217.1 - 5e-10 39.4 5.3 2e-05 25.1 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX92217.1 - 4.9e-07 29.9 6.1 1.1e-05 25.7 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX92217.1 - 6.9e-06 26.2 0.2 0.026 14.8 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX92217.1 - 0.00046 20.5 0.6 0.13 12.7 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORX92217.1 - 0.00078 19.2 1.4 0.65 9.8 0.1 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORX92217.1 - 0.0012 18.8 3.3 0.2 11.7 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX92217.1 - 0.023 14.4 1.1 0.023 14.4 1.1 2.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 ORX92217.1 - 0.024 14.8 4.1 0.078 13.1 0.3 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 ORX92217.1 - 0.088 13.3 2.5 1 9.9 2.5 2.0 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 ORX92217.1 - 0.1 12.6 0.7 0.93 9.6 0.1 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.12 ORX92217.1 - 0.11 12.8 2.5 0.18 12.1 2.5 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 ORX92217.1 - 0.15 12.0 0.4 1.6 8.6 0.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 ORX92217.1 - 0.21 12.3 2.9 13 6.5 0.6 2.0 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats PPR_2 PF13041.6 ORX92218.1 - 1.1e-51 172.8 21.4 1.2e-12 47.8 0.3 8.5 3 2 6 9 9 9 8 PPR repeat family PPR_3 PF13812.6 ORX92218.1 - 2.2e-41 139.7 10.6 7e-09 35.6 0.0 5.1 2 1 4 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX92218.1 - 2.4e-33 113.5 10.2 3e-06 26.8 0.0 9.0 9 0 0 9 9 9 8 PPR repeat PPR PF01535.20 ORX92218.1 - 2.2e-30 102.7 13.5 1.5e-07 31.2 0.0 9.2 10 1 0 10 10 10 6 PPR repeat PPR_long PF17177.4 ORX92218.1 - 6.9e-17 61.5 0.0 2.3e-06 27.1 0.1 3.2 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP YodL PF14191.6 ORX92218.1 - 0.019 15.8 3.1 17 6.3 0.0 3.7 3 1 1 4 4 4 0 YodL-like RPM2 PF08579.11 ORX92218.1 - 0.029 14.8 0.2 43 4.5 0.0 3.8 2 1 2 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX92218.1 - 0.036 13.0 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Peptidase_C39 PF03412.15 ORX92218.1 - 0.057 13.2 0.0 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Peptidase C39 family Aminotran_3 PF00202.21 ORX92219.1 - 4.3e-120 401.1 0.0 4.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX92219.1 - 0.0083 15.3 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX92219.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase OAM_dimer PF16554.5 ORX92219.1 - 0.067 13.7 0.5 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Aminotran_3 PF00202.21 ORX92220.1 - 4.3e-120 401.1 0.0 4.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX92220.1 - 0.0083 15.3 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX92220.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase OAM_dimer PF16554.5 ORX92220.1 - 0.066 13.7 0.5 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase ABC2_membrane PF01061.24 ORX92221.1 - 1.3e-65 220.7 63.0 2.1e-42 144.9 27.0 4.0 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORX92221.1 - 1.4e-15 58.0 0.0 4.3e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter PDR_CDR PF06422.12 ORX92221.1 - 3.6e-15 55.6 12.9 1.9e-10 40.5 0.4 3.9 3 1 0 3 3 3 2 CDR ABC transporter AAA_21 PF13304.6 ORX92221.1 - 1.3e-05 25.2 0.0 0.05 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORX92221.1 - 8.1e-05 21.9 13.4 8.1e-05 21.9 13.4 3.4 2 2 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX92221.1 - 0.00079 19.4 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORX92221.1 - 0.0033 17.8 0.0 0.0063 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORX92221.1 - 0.0058 16.3 0.2 0.015 15.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PDR_assoc PF08370.11 ORX92221.1 - 0.0073 16.0 2.0 0.0073 16.0 2.0 4.3 5 0 0 5 5 4 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 ORX92221.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORX92221.1 - 0.043 13.3 0.0 0.41 10.0 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 ORX92221.1 - 0.16 10.6 0.1 2.9 6.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 ORX92221.1 - 0.17 12.4 0.1 0.42 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain PYC_OADA PF02436.18 ORX92221.1 - 0.2 11.4 0.0 0.58 9.9 0.0 1.7 2 0 0 2 2 2 0 Conserved carboxylase domain cobW PF02492.19 ORX92221.1 - 0.23 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane PF01061.24 ORX92222.1 - 1e-90 302.8 58.9 7.4e-50 169.3 16.5 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORX92222.1 - 1.5e-33 116.2 0.0 2e-15 57.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORX92222.1 - 1.6e-27 95.2 2.7 2.4e-20 72.2 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORX92222.1 - 1.4e-11 44.1 29.6 4.6e-09 35.9 9.7 3.9 2 2 1 4 4 4 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 ORX92222.1 - 4.4e-09 36.8 0.1 1.4e-08 35.2 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 ORX92222.1 - 2.3e-06 27.6 0.1 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORX92222.1 - 4.2e-06 27.2 0.1 0.0084 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORX92222.1 - 1.8e-05 24.7 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORX92222.1 - 8.1e-05 22.3 0.7 0.018 14.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORX92222.1 - 0.00013 21.6 0.1 0.017 14.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX92222.1 - 0.00045 20.5 0.2 1.3 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX92222.1 - 0.0029 17.8 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 ORX92222.1 - 0.0055 16.4 1.4 0.0055 16.4 1.4 3.2 3 0 0 3 3 2 1 Plant PDR ABC transporter associated cobW PF02492.19 ORX92222.1 - 0.012 15.3 0.2 0.55 9.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORX92222.1 - 0.015 15.1 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX92222.1 - 0.015 15.3 0.1 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 ORX92222.1 - 0.031 14.7 0.1 5.3 7.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX92222.1 - 0.033 14.1 0.7 3.3 7.6 0.3 2.6 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 ORX92222.1 - 0.035 13.5 0.1 0.55 9.6 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ORX92222.1 - 0.039 14.2 0.4 0.71 10.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORX92222.1 - 0.039 14.5 0.0 4.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX92222.1 - 0.049 13.0 0.1 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ORX92222.1 - 0.08 13.4 0.9 0.52 10.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORX92222.1 - 0.12 12.3 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 ORX92222.1 - 0.14 11.9 0.9 4.8 6.9 0.4 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_17 PF00332.18 ORX92223.1 - 9.8e-16 58.2 0.6 8.2e-12 45.3 0.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_72 PF03198.14 ORX92223.1 - 0.011 15.0 1.2 0.061 12.6 0.2 2.2 1 1 1 2 2 2 0 Glucanosyltransferase DUF1473 PF07341.11 ORX92223.1 - 0.06 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) Lipase_GDSL PF00657.22 ORX92223.1 - 0.18 11.8 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase RPN13_C PF16550.5 ORX92224.1 - 0.025 14.8 0.8 0.058 13.6 0.8 1.6 1 1 0 1 1 1 0 UCH-binding domain STI1 PF17830.1 ORX92224.1 - 0.032 14.2 2.3 2.7 8.0 0.0 2.8 2 1 0 2 2 2 0 STI1 domain DUF1641 PF07849.11 ORX92224.1 - 0.041 13.8 0.3 0.7 9.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1641) DUF3484 PF11983.8 ORX92224.1 - 0.097 13.8 0.4 0.19 12.9 0.4 1.7 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch BCA_ABC_TP_C PF12399.8 ORX92224.1 - 0.14 12.1 0.2 12 6.0 0.0 2.8 3 0 0 3 3 3 0 Branched-chain amino acid ATP-binding cassette transporter Utp12 PF04003.12 ORX92225.1 - 6.7e-22 77.8 0.0 1.4e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 ORX92225.1 - 5e-06 27.1 4.6 0.00027 21.7 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92225.1 - 6.2e-06 26.4 1.3 1.7 9.0 0.3 4.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORX92225.1 - 0.0022 17.6 1.7 0.013 15.1 0.1 2.7 2 1 1 3 3 3 1 PQQ-like domain Fructosamin_kin PF03881.14 ORX92226.1 - 2.1e-91 306.1 0.0 2.4e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ORX92226.1 - 1.2e-19 71.2 0.0 1.5e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Arrestin_C PF02752.22 ORX92227.1 - 3.5e-14 53.4 0.3 1.5e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX92227.1 - 2.6e-13 50.2 0.1 4.5e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX92227.1 - 0.0018 18.0 0.0 0.0041 16.9 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like PI3Ka PF00613.20 ORX92228.1 - 1.7e-62 210.2 0.5 5.3e-62 208.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 ORX92228.1 - 9.4e-51 173.0 0.0 8.6e-48 163.3 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 ORX92228.1 - 3e-43 147.1 0.0 5.3e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 ORX92228.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Arrestin_C PF02752.22 ORX92229.1 - 3.8e-11 43.6 0.4 6.6e-11 42.8 0.4 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX92229.1 - 5.9e-11 42.6 0.0 1.8e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX92229.1 - 0.0026 17.5 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like HEM4 PF02602.15 ORX92231.1 - 2e-43 148.4 0.0 2.3e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Methyltransf_25 PF13649.6 ORX92232.1 - 4.9e-13 49.6 0.1 1.3e-12 48.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92232.1 - 2e-11 43.9 0.1 2.8e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORX92232.1 - 3.7e-10 39.7 0.1 5.6e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ORX92232.1 - 7.1e-10 39.4 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX92232.1 - 2.7e-08 33.5 0.1 3.7e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORX92232.1 - 4.7e-08 32.3 0.1 6.5e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 ORX92232.1 - 2.5e-06 27.4 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX92232.1 - 2.8e-05 23.8 0.1 4.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORX92232.1 - 4.9e-05 24.0 0.0 8.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORX92232.1 - 7.2e-05 22.8 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX92232.1 - 9.5e-05 22.2 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ORX92232.1 - 0.0002 20.8 0.1 0.00031 20.1 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 ORX92232.1 - 0.00087 18.7 2.3 0.0069 15.8 0.6 2.5 2 1 0 2 2 2 1 Tellurite resistance protein TehB Met_10 PF02475.16 ORX92232.1 - 0.0058 16.4 0.2 0.0093 15.7 0.2 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 ORX92232.1 - 0.0065 16.2 0.2 0.0095 15.7 0.2 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 ORX92232.1 - 0.008 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 ORX92232.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 ORX92232.1 - 0.052 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 ORX92232.1 - 0.069 12.6 1.1 0.086 12.3 0.3 1.6 2 0 0 2 2 1 0 Putative methyltransferase Methyltransf_24 PF13578.6 ORX92232.1 - 0.1 13.6 0.0 0.18 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 ORX92232.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CRAL_TRIO PF00650.20 ORX92233.1 - 1.9e-19 70.0 0.1 5.1e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORX92233.1 - 3.9e-10 40.0 0.0 3.5e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain SAC3_GANP PF03399.16 ORX92234.1 - 6.9e-113 376.9 4.4 1.3e-112 376.0 4.4 1.5 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORX92234.1 - 0.013 15.5 1.2 0.039 13.9 0.0 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Acetyltransf_4 PF13420.7 ORX92240.1 - 1.1e-20 74.4 0.0 1.2e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX92240.1 - 3.4e-16 59.5 0.1 4.2e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 ORX92240.1 - 2.1e-12 47.9 0.0 2.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX92240.1 - 3.9e-10 40.0 0.0 5.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX92240.1 - 9.3e-08 31.9 0.1 1.6e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORX92240.1 - 1.2e-07 31.7 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORX92240.1 - 0.00044 19.9 0.0 0.00056 19.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 ORX92240.1 - 0.068 13.2 0.0 0.22 11.6 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Prismane PF03063.20 ORX92241.1 - 3.9e-138 461.3 0.0 5.2e-138 460.9 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 ORX92241.1 - 4.4e-49 167.0 1.0 5.7e-49 166.7 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX92241.1 - 4.6e-29 101.4 0.0 9.5e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORX92241.1 - 3.1e-06 27.8 0.1 3.1e-05 24.6 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain VIT1 PF01988.19 ORX92241.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 VIT family NAD_binding_6 PF08030.12 ORX92241.1 - 0.19 11.8 0.2 1.2 9.2 0.0 2.3 3 0 0 3 3 3 0 Ferric reductase NAD binding domain HSF_DNA-bind PF00447.17 ORX92242.1 - 3.5e-28 98.1 0.3 3.9e-28 97.9 0.3 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Arginosuc_synth PF00764.19 ORX92243.1 - 1.1e-154 515.4 0.0 1.3e-154 515.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORX92243.1 - 0.0051 16.3 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORX92243.1 - 0.034 13.0 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.19 ORX92244.1 - 1.1e-154 515.4 0.0 1.3e-154 515.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORX92244.1 - 0.0051 16.3 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORX92244.1 - 0.034 13.0 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.19 ORX92245.1 - 1.1e-154 515.4 0.0 1.3e-154 515.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORX92245.1 - 0.0051 16.3 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORX92245.1 - 0.034 13.0 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Rad60-SLD PF11976.8 ORX92247.1 - 4e-19 68.2 0.2 3.4e-16 58.8 0.7 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORX92247.1 - 0.0058 16.4 3.0 0.008 15.9 0.5 2.2 1 1 1 2 2 2 1 Ubiquitin family Not3 PF04065.15 ORX92247.1 - 0.0069 15.8 1.7 0.0091 15.5 1.7 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component LAGLIDADG_1 PF00961.19 ORX92247.1 - 0.14 13.1 0.3 0.2 12.7 0.3 1.2 1 0 0 1 1 1 0 LAGLIDADG endonuclease LSM PF01423.22 ORX92248.1 - 5.5e-17 61.2 0.0 7e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX92248.1 - 0.0069 16.5 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain ATP_sub_h PF10775.9 ORX92249.1 - 6.1e-24 83.8 0.7 7.3e-24 83.6 0.7 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h Sigma70_r2 PF04542.14 ORX92249.1 - 0.09 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-70 region 2 TAF4 PF05236.14 ORX92250.1 - 4.3e-40 138.2 4.4 2.1e-39 136.0 4.4 1.9 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family RST PF12174.8 ORX92250.1 - 0.002 18.0 0.1 0.0057 16.5 0.1 1.7 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain AT_hook PF02178.19 ORX92250.1 - 0.033 14.0 1.9 0.48 10.5 0.4 3.0 2 0 0 2 2 2 0 AT hook motif TPR_2 PF07719.17 ORX92251.1 - 1.5e-40 134.1 31.9 3.5e-07 29.8 0.1 15.9 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92251.1 - 4.9e-40 133.8 30.3 1.5e-07 30.9 0.0 14.9 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92251.1 - 6.7e-32 109.6 20.4 7.3e-05 23.0 1.1 10.1 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92251.1 - 9.5e-32 109.3 18.4 0.0011 19.4 0.6 10.2 8 2 1 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92251.1 - 2.9e-30 102.4 20.4 0.0009 19.9 0.1 16.0 9 4 8 17 17 17 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92251.1 - 2.2e-27 92.9 28.7 1.3e-05 25.0 0.0 15.7 17 0 0 17 17 16 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX92251.1 - 2.5e-22 78.3 18.9 4e-06 26.4 0.0 11.1 9 2 3 12 12 11 5 TPR repeat TPR_16 PF13432.6 ORX92251.1 - 4.2e-22 78.5 22.4 1.5e-07 32.0 0.0 9.0 9 3 2 11 11 8 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92251.1 - 1.4e-20 72.5 32.4 0.046 14.4 0.0 14.5 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92251.1 - 2e-17 61.9 20.1 0.3 11.2 0.0 11.9 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORX92251.1 - 8.8e-15 53.9 15.6 0.25 11.8 0.0 12.8 15 1 0 15 15 14 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORX92251.1 - 6.5e-10 39.0 8.9 0.0023 18.0 0.0 7.7 6 3 3 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX92251.1 - 5.5e-09 36.1 14.2 0.0048 17.1 0.0 5.9 5 2 3 8 8 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORX92251.1 - 3.7e-07 29.8 14.8 0.14 12.1 0.2 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat PknG_TPR PF16918.5 ORX92251.1 - 1.9e-06 26.9 0.1 0.61 8.8 0.0 4.3 3 0 0 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 ORX92251.1 - 2.3e-05 23.8 16.5 0.00033 20.0 0.3 5.7 3 2 2 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 ORX92251.1 - 0.00067 19.2 23.6 0.0045 16.4 6.9 5.3 3 3 2 5 5 5 3 Soluble NSF attachment protein, SNAP DUF2989 PF11207.8 ORX92251.1 - 0.0021 17.8 0.4 0.0021 17.8 0.4 5.1 7 0 0 7 7 6 1 Protein of unknown function (DUF2989) HrpB1_HrpK PF09613.10 ORX92251.1 - 0.077 12.6 0.0 7.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 ORX92251.1 - 0.65 10.8 8.0 8.5 7.3 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORX92251.1 - 1 9.4 10.9 1 9.4 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 ORX92252.1 - 3.7e-49 166.1 3.1 5.8e-49 165.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORX92252.1 - 5.1e-16 58.4 0.0 1.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MSL1_dimer PF16801.5 ORX92253.1 - 0.059 13.1 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 PI3_PI4_kinase PF00454.27 ORX92254.1 - 6.4e-42 144.1 0.0 9.7e-40 137.0 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORX92254.1 - 2e-20 73.0 0.2 4.3e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cohesin_load PF10345.9 ORX92255.1 - 3.4e-55 187.6 17.8 3.8e-52 177.6 16.7 2.0 2 0 0 2 2 2 2 Cohesin loading factor TPR_12 PF13424.6 ORX92255.1 - 2.5e-06 27.7 13.9 0.1 12.9 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX92255.1 - 0.0027 17.7 15.0 0.052 13.7 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92255.1 - 0.0078 16.7 3.7 13 6.4 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92255.1 - 0.059 13.2 8.3 0.35 10.8 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92255.1 - 0.13 12.6 3.8 17 5.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX92255.1 - 0.46 10.4 3.2 43 4.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92255.1 - 9.8 6.5 9.3 0.84 9.8 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Histone PF00125.24 ORX92256.1 - 1.3e-44 151.7 2.1 1.3e-44 151.7 2.1 1.6 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORX92256.1 - 0.0037 17.4 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORX92256.1 - 0.0059 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX92256.1 - 0.024 14.9 1.3 0.043 14.1 0.3 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCMT PF01135.19 ORX92257.1 - 1.8e-77 259.8 0.0 2.2e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORX92257.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX92257.1 - 8.9e-08 32.7 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX92257.1 - 3.3e-05 23.3 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ORX92257.1 - 0.0002 22.0 0.0 0.00033 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORX92257.1 - 0.00025 21.1 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX92257.1 - 0.00055 19.8 0.0 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX92257.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 ORX92257.1 - 0.0021 17.2 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 ORX92257.1 - 0.0039 16.6 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Fibrillarin PF01269.17 ORX92257.1 - 0.0046 16.1 0.1 0.0077 15.4 0.1 1.3 1 0 0 1 1 1 1 Fibrillarin CMAS PF02353.20 ORX92257.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase EF-hand_1 PF00036.32 ORX92257.1 - 0.05 13.2 0.0 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 ORX92257.1 - 0.1 12.6 0.1 2.4 8.3 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Methyltransf_24 PF13578.6 ORX92257.1 - 0.15 13.1 0.0 0.35 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 ORX92257.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Pkinase PF00069.25 ORX92258.1 - 7.6e-70 235.3 0.0 9.2e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92258.1 - 1.2e-32 113.3 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX92258.1 - 0.0022 17.4 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX92258.1 - 0.0024 16.9 0.2 0.0043 16.0 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX92258.1 - 0.0037 16.6 0.0 0.007 15.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORX92258.1 - 0.0053 16.4 0.1 0.042 13.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 ORX92258.1 - 0.031 13.1 0.0 0.071 11.9 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 ORX92258.1 - 0.033 13.0 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC TFIID_20kDa PF03847.13 ORX92259.1 - 1.4e-29 102.4 0.9 1.5e-29 102.2 0.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 ORX92259.1 - 9.1e-08 32.3 0.1 9.1e-08 32.3 0.1 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX92259.1 - 5.6e-07 30.0 0.1 5.7e-07 30.0 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORX92259.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 ORX92259.1 - 0.05 13.6 0.1 0.05 13.6 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1325 PF07039.11 ORX92261.1 - 8.4e-13 48.6 0.0 8.5e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 SGF29 tudor-like domain NMT_C PF02799.15 ORX92262.1 - 5.7e-71 238.3 0.3 7.9e-71 237.9 0.3 1.1 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 ORX92262.1 - 7e-71 237.2 0.0 1.2e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 ORX92262.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX92262.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EBP PF05241.12 ORX92263.1 - 7.5e-55 185.1 4.2 8.9e-55 184.9 4.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein LPMO_10 PF03067.15 ORX92264.1 - 1.6e-05 25.6 0.1 3.4e-05 24.6 0.0 1.6 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX92264.1 - 0.0074 16.2 0.6 0.58 10.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 HSP70 PF00012.20 ORX92265.1 - 2.5e-50 171.3 1.5 3e-50 171.1 1.5 1.1 1 0 0 1 1 1 1 Hsp70 protein Transferase PF02458.15 ORX92266.1 - 9.7e-22 77.2 0.0 1.9e-21 76.2 0.0 1.4 2 0 0 2 2 2 1 Transferase family FAD_binding_4 PF01565.23 ORX92267.1 - 2.4e-29 101.8 1.8 4.5e-29 101.0 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX92267.1 - 3.8e-17 62.1 5.0 3.8e-17 62.1 5.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 ORX92267.1 - 0.013 14.9 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CreA PF05981.12 ORX92268.1 - 0.068 13.1 0.2 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 CreA protein DUF4681 PF15732.5 ORX92268.1 - 0.11 12.8 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4681) Acetyltransf_5 PF13444.6 ORX92269.1 - 1.5e-07 32.1 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX92269.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX92269.1 - 0.00015 21.7 0.0 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX92269.1 - 0.00025 21.1 0.0 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain RRM_2 PF04059.12 ORX92270.1 - 1.5e-44 150.1 1.0 1.8e-44 149.9 1.0 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ORX92270.1 - 0.021 14.6 0.2 0.052 13.4 0.1 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 ORX92270.1 - 0.045 14.0 0.2 0.06 13.6 0.2 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 SAM_1 PF00536.30 ORX92271.1 - 1.4e-07 31.8 0.9 0.0081 16.6 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORX92271.1 - 1.1e-05 25.5 2.1 0.031 14.4 0.4 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase PF00069.25 ORX92272.1 - 2e-70 237.2 0.0 2.7e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92272.1 - 5.2e-53 180.0 0.0 7.8e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX92272.1 - 2e-08 33.9 0.0 7e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORX92272.1 - 0.0043 15.9 0.2 0.0043 15.9 0.2 1.7 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX92272.1 - 0.038 13.9 0.0 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family SRF-TF PF00319.18 ORX92273.1 - 5.7e-19 67.3 0.1 1e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MORN PF02493.20 ORX92275.1 - 1.9e-16 58.9 31.0 0.00015 21.4 3.3 6.9 8 0 0 8 8 8 4 MORN repeat SET PF00856.28 ORX92275.1 - 9.4e-06 26.1 1.5 0.00012 22.5 1.5 2.1 1 1 0 1 1 1 1 SET domain DUF3048_C PF17479.2 ORX92275.1 - 0.00068 20.0 0.2 0.4 11.1 0.0 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF3048) C-terminal domain MORN_2 PF07661.13 ORX92275.1 - 0.043 14.0 0.2 0.043 14.0 0.2 5.0 6 0 0 6 6 6 0 MORN repeat variant Ribosomal_S27e PF01667.17 ORX92276.1 - 2.4e-30 104.0 4.3 2.9e-30 103.7 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORX92276.1 - 0.15 11.6 3.2 0.23 11.0 3.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Peptidase_M24 PF00557.24 ORX92277.1 - 5.2e-59 199.4 0.0 1.5e-58 198.0 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 ORX92277.1 - 4.7e-10 39.3 0.0 8.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AMP_N PF05195.16 ORX92278.1 - 1.2e-14 54.1 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GST_C_3 PF14497.6 ORX92280.1 - 3.3e-11 43.3 0.5 7.7e-11 42.1 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX92280.1 - 1.2e-05 25.6 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX92280.1 - 0.00096 19.4 0.0 0.0033 17.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX92280.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX92280.1 - 0.0021 18.4 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORX92280.1 - 0.0098 16.6 0.0 0.018 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF4853 PF16145.5 ORX92280.1 - 0.026 14.7 0.0 0.058 13.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4853) ADH_zinc_N_2 PF13602.6 ORX92281.1 - 8.7e-27 94.8 0.1 2.1e-26 93.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX92281.1 - 1.4e-18 67.1 1.2 2.9e-18 66.1 0.2 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX92281.1 - 9.5e-11 41.6 0.1 2.6e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORX92281.1 - 0.0023 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Semialdhyde_dh PF01118.24 ORX92281.1 - 0.0041 17.5 0.0 0.0083 16.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 ORX92281.1 - 0.0085 16.7 0.1 0.045 14.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Glu_dehyd_C PF16912.5 ORX92281.1 - 0.011 15.3 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORX92281.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3240 PF11582.8 ORX92281.1 - 0.11 12.6 0.1 1.4 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3240) BRCA-2_OB3 PF09104.10 ORX92281.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 ADH_zinc_N_2 PF13602.6 ORX92282.1 - 3.6e-26 92.8 0.1 8.5e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX92282.1 - 6.5e-19 68.2 0.4 2.4e-18 66.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX92282.1 - 1.7e-10 40.7 0.0 4.1e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORX92282.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Semialdhyde_dh PF01118.24 ORX92282.1 - 0.0028 18.1 0.0 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain BRCA-2_OB3 PF09104.10 ORX92282.1 - 0.017 14.8 0.0 0.044 13.4 0.0 1.6 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Glu_dehyd_C PF16912.5 ORX92282.1 - 0.023 14.2 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Methyltransf_11 PF08241.12 ORX92282.1 - 0.032 14.9 0.2 0.15 12.7 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 ORX92282.1 - 0.092 12.0 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PTR2 PF00854.21 ORX92283.1 - 8.8e-80 268.5 9.4 8.8e-80 268.5 9.4 1.8 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX92283.1 - 4.5e-14 52.2 27.4 5.6e-08 32.1 9.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily PTR2 PF00854.21 ORX92284.1 - 1.8e-80 270.7 6.7 1.8e-80 270.7 6.7 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX92284.1 - 4.5e-14 52.1 27.4 5.6e-08 32.1 9.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Asp PF00026.23 ORX92285.1 - 1.8e-39 136.0 6.0 3.8e-39 135.0 6.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX92285.1 - 3.3e-08 34.0 8.5 6.9e-05 23.1 0.2 2.8 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal PTR2 PF00854.21 ORX92286.1 - 1e-79 268.2 9.5 1e-79 268.2 9.5 1.8 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX92286.1 - 4.3e-14 52.2 27.4 5.7e-08 32.1 9.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 ORX92287.1 - 1.8e-16 60.4 0.1 2.1e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX92287.1 - 8.8e-12 45.3 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX92287.1 - 6.3e-09 35.8 0.0 7.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX92287.1 - 0.00081 19.6 0.1 0.0016 18.6 0.1 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX92287.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORX92287.1 - 0.0072 17.0 0.0 0.0082 16.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX92287.1 - 0.035 14.2 0.0 0.56 10.3 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PTR2 PF00854.21 ORX92288.1 - 9.9e-80 268.3 7.1 9.9e-80 268.3 7.1 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX92288.1 - 1.9e-14 53.4 26.9 2e-08 33.6 8.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Asp PF00026.23 ORX92289.1 - 1.7e-49 168.9 6.1 3.5e-49 168.0 6.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX92289.1 - 1.3e-08 35.2 8.0 0.0019 18.5 8.0 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX92289.1 - 0.014 15.2 0.1 0.3 10.9 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Aminotran_1_2 PF00155.21 ORX92298.1 - 5.3e-40 137.7 0.0 1.2e-39 136.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX92298.1 - 0.002 17.4 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Nop PF01798.18 ORX92299.1 - 8.6e-86 287.1 0.3 2e-85 285.9 0.3 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORX92299.1 - 4.8e-22 78.1 1.0 4.8e-22 78.1 1.0 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 ORX92299.1 - 2.2 8.3 36.3 0.032 14.3 29.2 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 ORX92299.1 - 3.6 7.3 16.2 7.6 6.3 16.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 ORX92299.1 - 5.9 7.1 13.1 11 6.2 13.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Apc13p PF05839.11 ORX92300.1 - 4.5e-10 39.6 5.0 1.1e-09 38.3 1.0 2.0 1 1 1 2 2 2 2 Apc13p protein PAS_3 PF08447.12 ORX92301.1 - 2.5e-16 59.7 0.0 2.9e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORX92301.1 - 1.7e-08 34.6 0.0 0.00076 19.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORX92301.1 - 1.1e-07 31.9 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORX92301.1 - 0.00029 21.1 0.0 0.063 13.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 ORX92301.1 - 0.00042 20.9 0.0 0.44 11.2 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 ORX92301.1 - 0.028 14.5 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain Ribosomal_S7 PF00177.21 ORX92302.1 - 1.4e-37 128.7 0.7 1.6e-37 128.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S14 PF00253.21 ORX92303.1 - 3.8e-15 55.4 4.2 4.2e-15 55.2 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ORX92303.1 - 0.028 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) bZIP_1 PF00170.21 ORX92304.1 - 1.2e-13 50.9 10.6 1.7e-13 50.4 10.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX92304.1 - 2e-08 34.2 8.3 3.4e-08 33.4 8.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX92304.1 - 0.0028 18.1 7.1 0.0045 17.5 7.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ORX92304.1 - 0.034 13.5 3.8 0.055 12.8 3.8 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SID-1_RNA_chan PF13965.6 ORX92304.1 - 0.34 9.3 1.3 0.4 9.0 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 ORX92304.1 - 0.96 7.7 5.3 1.1 7.4 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF334 PF03904.13 ORX92304.1 - 2.9 7.3 5.2 3.9 6.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) UCR_hinge PF02320.16 ORX92305.1 - 1.3e-25 89.3 5.3 1.3e-25 89.3 5.3 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Euplotes_phero PF05842.11 ORX92305.1 - 0.024 15.2 1.3 0.028 15.0 1.3 1.1 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein CX9C PF16860.5 ORX92305.1 - 0.093 12.8 4.8 2.3 8.3 0.2 2.4 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pox_RNA_Pol_19 PF05320.12 ORX92305.1 - 2.4 8.1 6.1 2.8 7.9 6.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-C3HC4_3 PF13920.6 ORX92306.1 - 1.8e-07 30.9 9.2 2.9e-07 30.3 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX92306.1 - 6.8e-07 29.1 11.5 1.2e-06 28.2 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX92306.1 - 1.4e-05 25.3 11.4 3.2e-05 24.2 11.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX92306.1 - 1.8e-05 24.5 9.9 0.00031 20.5 11.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX92306.1 - 0.00018 21.4 10.5 0.00055 19.8 10.5 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX92306.1 - 0.00019 21.4 8.6 0.001 19.0 9.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.20 ORX92306.1 - 0.011 15.5 15.3 0.017 14.9 12.3 2.7 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 ORX92306.1 - 0.023 14.5 8.6 0.072 13.0 8.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ACC PF17848.1 ORX92306.1 - 0.048 13.7 1.1 0.16 12.1 1.1 1.9 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-ANAPC11 PF12861.7 ORX92306.1 - 0.064 13.3 3.8 0.12 12.5 3.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 ORX92306.1 - 0.23 11.7 11.5 0.61 10.3 11.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORX92306.1 - 0.33 11.3 7.6 0.92 9.8 7.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 ORX92306.1 - 0.81 9.9 6.1 1.9 8.7 6.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 ORX92306.1 - 0.99 9.6 7.5 2.6 8.2 7.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 WD40 PF00400.32 ORX92307.1 - 2.9e-50 167.1 25.4 1.1e-08 35.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92307.1 - 8.5e-13 48.4 2.4 0.059 13.7 0.0 5.1 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX92307.1 - 5.4e-05 22.3 0.2 0.98 8.3 0.0 4.2 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 ORX92307.1 - 0.00026 20.2 0.0 0.018 14.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) eIF2A PF08662.11 ORX92307.1 - 0.00043 20.2 0.1 0.17 11.8 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORX92307.1 - 0.0025 16.5 7.1 0.031 12.9 0.1 4.6 2 2 3 6 6 6 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORX92307.1 - 0.022 13.3 0.1 1.4 7.4 0.1 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 ORX92307.1 - 0.11 12.5 0.8 38 4.4 0.1 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat BatA PF07584.11 ORX92309.1 - 1.4 9.4 11.6 0.4 11.1 0.4 3.0 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal TMEM132D_N PF15705.5 ORX92310.1 - 0.0018 18.1 0.0 0.0082 16.0 0.0 1.8 1 1 1 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Tobravirus_2B PF05271.11 ORX92310.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Tobravirus 2B protein FXR_C1 PF16096.5 ORX92315.1 - 9.9 6.4 11.2 8.1 6.7 5.6 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF4865 PF16157.5 ORX92320.1 - 0.018 15.0 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) Myticin-prepro PF10690.9 ORX92325.1 - 0.0034 17.6 0.3 0.0057 16.9 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Aminotran_1_2 PF00155.21 ORX92331.1 - 6.4e-64 216.4 0.0 7.3e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX92331.1 - 1.3e-06 27.9 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORX92331.1 - 0.00036 19.6 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORX92331.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORX92331.1 - 0.0024 16.5 0.0 0.0038 15.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 ORX92331.1 - 0.0035 16.1 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Methyltransf_12 PF08242.12 ORX92332.1 - 4.4e-16 59.4 0.0 8.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX92332.1 - 6.6e-15 55.3 0.0 2e-14 53.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX92332.1 - 3.8e-12 46.8 0.0 6.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92332.1 - 4.5e-08 33.0 0.0 9.1e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX92332.1 - 1.3e-07 32.2 0.0 2.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX92332.1 - 7.3e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORX92332.1 - 0.0029 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase cwf18 PF08315.12 ORX92333.1 - 1.8e-32 112.8 13.4 2.8e-32 112.2 13.4 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor XhlA PF10779.9 ORX92333.1 - 1.1 9.5 9.7 2 8.7 3.2 2.5 2 1 0 2 2 2 0 Haemolysin XhlA zf-RING_UBOX PF13445.6 ORX92334.1 - 4.2e-11 42.7 4.9 4.2e-11 42.7 4.9 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORX92334.1 - 8.7e-09 35.1 6.3 8.7e-09 35.1 6.3 3.5 1 1 1 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX92334.1 - 1.7e-08 34.2 4.2 1.7e-08 34.2 4.2 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORX92334.1 - 2.5e-08 34.0 3.6 2.5e-08 34.0 3.6 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORX92334.1 - 2.3e-07 30.7 4.7 2.3e-07 30.7 4.7 3.0 2 2 1 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORX92334.1 - 5.5e-07 29.8 9.7 5.5e-07 29.8 9.7 3.3 2 2 0 2 2 2 1 Ring finger domain zf-TRAF PF02176.18 ORX92334.1 - 5.6e-07 30.1 6.6 5.6e-07 30.1 6.6 2.2 2 0 0 2 2 2 1 TRAF-type zinc finger zf-Nse PF11789.8 ORX92334.1 - 1.7e-06 27.7 5.5 1.7e-06 27.7 5.5 2.7 3 1 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 ORX92334.1 - 0.00047 20.0 1.4 0.00047 20.0 1.4 3.9 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORX92334.1 - 0.036 14.2 1.9 0.036 14.2 1.9 3.2 3 1 0 3 3 3 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 ORX92334.1 - 0.041 13.9 0.8 0.041 13.9 0.8 2.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 ORX92334.1 - 0.13 12.4 0.2 0.63 10.3 0.1 2.3 2 1 0 2 2 2 0 U-box domain zf-RING_6 PF14835.6 ORX92334.1 - 0.28 11.1 5.6 0.13 12.1 2.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORX92334.1 - 0.87 9.4 0.0 0.87 9.4 0.0 4.6 3 2 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 ORX92334.1 - 2.6 8.0 21.1 0.31 10.9 6.9 3.9 4 1 1 5 5 4 0 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 ORX92334.1 - 4.3 7.9 13.8 0.82 10.2 5.8 2.7 1 1 2 3 3 3 0 TRAF-like zinc-finger Fer2 PF00111.27 ORX92335.1 - 1.4e-13 50.6 0.2 1.9e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ntox47 PF15540.6 ORX92335.1 - 0.025 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 47 MCR PF18509.1 ORX92335.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Magnetochrome domain LSM PF01423.22 ORX92336.1 - 7.7e-19 67.2 0.4 1e-18 66.8 0.4 1.2 1 0 0 1 1 1 1 LSM domain LNS2 PF08235.13 ORX92336.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Fis1_TPR_C PF14853.6 ORX92337.1 - 1.5e-20 72.9 1.1 3e-20 72.0 1.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORX92337.1 - 1.2e-11 44.0 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ORX92337.1 - 1.4e-05 24.9 4.9 1.8e-05 24.5 2.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92337.1 - 2.1e-05 24.9 0.2 3.8e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX92337.1 - 0.00087 19.5 0.9 0.0013 18.9 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORX92337.1 - 0.0069 17.0 0.6 0.046 14.4 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92337.1 - 0.02 15.2 1.7 0.061 13.6 0.5 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92337.1 - 0.1 12.4 2.6 0.21 11.5 2.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat COPI_C PF06957.11 ORX92337.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TPR_7 PF13176.6 ORX92337.1 - 0.17 12.0 2.2 3 8.1 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX92337.1 - 3.2 7.7 4.9 0.7 9.8 0.4 2.3 2 1 0 3 3 3 0 Tetratricopeptide repeat PhoD PF09423.10 ORX92338.1 - 1.7e-36 126.0 4.2 6.9e-36 124.0 4.2 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORX92338.1 - 0.0028 18.1 0.0 0.012 16.2 0.0 2.1 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ORX92338.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.3 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain SLS PF14611.6 ORX92339.1 - 1.9e-14 54.1 0.4 3.5e-14 53.2 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 ORX92339.1 - 2.9e-05 23.8 0.2 0.028 14.2 0.6 2.6 2 0 0 2 2 2 2 KH domain PPS_PS PF02006.16 ORX92339.1 - 0.0066 16.0 0.3 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase Thioredoxin_6 PF13848.6 ORX92339.1 - 0.04 13.8 1.9 0.28 11.1 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain DUF4422 PF14393.6 ORX92339.1 - 0.041 13.7 0.2 0.093 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Ish1 PF10281.9 ORX92339.1 - 0.044 14.1 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SAP30_Sin3_bdg PF13867.6 ORX92339.1 - 0.076 13.4 0.0 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF5617 PF18493.1 ORX92339.1 - 0.082 13.0 0.8 0.23 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Glyco_hydro_63 PF03200.16 ORX92341.1 - 2.5e-180 600.4 7.2 3e-179 596.9 7.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ORX92341.1 - 2e-73 247.2 0.2 6.7e-73 245.5 0.0 1.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 ORX92341.1 - 0.00028 19.9 0.0 0.00069 18.7 0.0 1.6 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 ORX92341.1 - 0.0045 15.9 1.3 0.0087 14.9 0.2 1.9 2 0 0 2 2 2 1 Trehalase SAP PF02037.27 ORX92342.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 SAP domain BatA PF07584.11 ORX92342.1 - 0.023 15.0 1.0 0.19 12.1 0.2 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Afaf PF15339.6 ORX92342.1 - 0.034 13.9 0.2 0.055 13.2 0.2 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2894 PF11445.8 ORX92343.1 - 0.03 14.8 0.2 0.035 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) SAP130_C PF16014.5 ORX92343.1 - 7.8 5.5 10.6 10 5.1 10.6 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus OTU PF02338.19 ORX92344.1 - 2.8e-05 24.6 0.0 4.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UBX PF00789.20 ORX92344.1 - 0.00079 19.6 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain Peptidase_C65 PF10275.9 ORX92344.1 - 0.037 13.5 0.7 2.3 7.6 0.0 2.8 1 1 1 2 2 2 0 Peptidase C65 Otubain MT-A70 PF05063.14 ORX92345.1 - 1.8e-57 194.0 0.0 2.8e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 MT-A70 PAP2 PF01569.21 ORX92346.1 - 6.1e-13 48.7 4.4 1.1e-12 47.9 4.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 ORX92346.1 - 0.0018 18.4 1.0 0.1 12.7 0.1 2.3 1 1 1 2 2 2 2 Divergent PAP2 family DUF3382 PF11862.8 ORX92346.1 - 0.055 13.8 1.2 0.59 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) MerC PF03203.14 ORX92346.1 - 2.1 8.9 6.1 2.5 8.6 3.4 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein Isochorismatase PF00857.20 ORX92347.1 - 5.2e-18 65.8 0.0 5.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 ORX92348.1 - 5.2e-15 56.0 0.0 7.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family RAP1 PF07218.11 ORX92354.1 - 0.033 12.5 2.4 0.044 12.1 2.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pneumo_att_G PF05539.11 ORX92354.1 - 0.33 10.5 13.9 0.49 9.9 13.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RAP1 PF07218.11 ORX92355.1 - 0.042 12.1 1.8 0.056 11.7 1.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pneumo_att_G PF05539.11 ORX92355.1 - 0.27 10.8 12.8 0.39 10.2 12.8 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SMG1_N PF17229.2 ORX92362.1 - 0.13 13.0 2.4 0.32 11.8 0.9 2.4 1 1 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal Methyltransf_3 PF01596.17 ORX92363.1 - 1.9e-17 63.2 0.1 2.3e-17 62.9 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX92363.1 - 1.7e-12 48.3 0.0 2.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92363.1 - 0.0005 19.9 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX92363.1 - 0.017 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 ORX92363.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 ORX92364.1 - 3.9e-08 32.7 0.0 7.2e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX92364.1 - 1.2e-06 29.5 0.0 1.9e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX92364.1 - 0.033 13.8 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 ORX92365.1 - 4.7e-46 157.3 52.5 4.7e-46 157.3 52.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX92365.1 - 7.5e-14 51.1 27.1 1.1e-13 50.5 27.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX92365.1 - 6.2e-13 48.4 11.5 6.2e-13 48.4 11.5 3.7 3 1 1 4 4 4 1 Sugar (and other) transporter DUF4407 PF14362.6 ORX92365.1 - 2.1 7.6 4.7 7.5 5.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_3 PF01596.17 ORX92366.1 - 2.2e-14 53.2 0.1 2.6e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX92366.1 - 3.9e-10 40.7 0.0 4.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_7 PF03492.15 ORX92367.1 - 2.3e-35 122.4 0.1 3.6e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase MFS_1 PF07690.16 ORX92368.1 - 3.9e-45 154.3 52.1 3.9e-45 154.3 52.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX92368.1 - 8.5e-16 57.5 21.2 1.1e-15 57.1 21.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX92368.1 - 6.7e-14 51.6 10.8 6.7e-14 51.6 10.8 3.6 3 1 0 3 3 3 1 Sugar (and other) transporter MPS-4 PF17523.2 ORX92368.1 - 3.3 7.9 6.0 12 6.1 0.5 3.0 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Kinesin PF00225.23 ORX92369.1 - 2.5e-96 322.5 0.6 4.6e-96 321.6 0.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX92369.1 - 3.6e-19 69.2 1.8 8.9e-16 58.2 0.0 3.3 3 0 0 3 3 3 2 Microtubule binding P5CR_dimer PF14748.6 ORX92370.1 - 1.6e-34 118.2 1.1 3.3e-34 117.2 1.1 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORX92370.1 - 9.1e-15 55.0 2.0 1.8e-14 54.0 0.7 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ORX92370.1 - 0.0073 17.1 0.2 0.022 15.6 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 ORX92370.1 - 0.0092 16.0 0.0 0.027 14.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Phage_Mu_Gp45 PF06890.12 ORX92370.1 - 0.072 12.8 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein HycI PF01750.18 ORX92370.1 - 0.075 12.9 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase maturation protease P5CR_dimer PF14748.6 ORX92371.1 - 5.8e-34 116.5 1.6 1.2e-33 115.4 1.6 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORX92371.1 - 3.6e-13 49.9 0.3 3.6e-13 49.9 0.3 2.4 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ORX92371.1 - 0.056 14.3 0.1 0.17 12.7 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold HycI PF01750.18 ORX92371.1 - 0.088 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase maturation protease Shikimate_DH PF01488.20 ORX92371.1 - 0.12 12.4 0.1 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Xan_ur_permease PF00860.20 ORX92372.1 - 3.2e-65 220.3 35.6 9.6e-64 215.5 35.6 2.1 1 1 0 1 1 1 1 Permease family PRP38 PF03371.15 ORX92373.1 - 7e-60 201.9 0.2 9e-60 201.5 0.2 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 ORX92373.1 - 0.022 15.4 99.6 12 6.5 69.0 2.6 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Xan_ur_permease PF00860.20 ORX92374.1 - 4.3e-65 219.9 35.2 1.3e-63 215.1 35.2 2.1 1 1 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 ORX92375.1 - 3.9e-60 203.6 32.1 1.3e-58 198.6 32.1 2.3 1 1 0 1 1 1 1 Permease family Chitin_synth_2 PF03142.15 ORX92376.1 - 9.2e-121 404.0 4.7 3.9e-81 273.3 0.1 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX92376.1 - 7.5e-12 45.6 4.1 7.5e-12 45.6 4.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX92376.1 - 2.8e-11 43.8 0.0 8.2e-08 32.4 0.0 2.8 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX92376.1 - 0.00013 21.8 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Peptidase_S8 PF00082.22 ORX92377.1 - 1.8e-39 135.8 0.4 2.5e-39 135.3 0.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORX92377.1 - 3.3e-28 97.5 0.4 6.5e-28 96.6 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 ORX92377.1 - 0.027 15.0 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family ATP-synt_I PF03899.15 ORX92377.1 - 0.13 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 ATP synthase I chain Ribosomal_L22e PF01776.17 ORX92378.1 - 1.4e-49 167.0 2.3 1.8e-49 166.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family T4_Gp59_N PF08993.10 ORX92378.1 - 0.057 13.8 2.1 0.44 11.0 0.4 2.1 1 1 1 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase S8_pro-domain PF16470.5 ORX92379.1 - 0.0029 18.3 2.4 0.041 14.7 2.3 2.2 1 1 0 1 1 1 1 Peptidase S8 pro-domain Forkhead PF00250.18 ORX92380.1 - 7.7e-38 128.6 0.0 9.6e-38 128.3 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain ADK PF00406.22 ORX92381.1 - 2e-61 206.5 0.0 2.4e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORX92381.1 - 1.5e-22 80.5 0.1 3.9e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORX92381.1 - 3e-17 62.3 0.1 8.8e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 ORX92381.1 - 0.0005 20.2 0.0 0.00092 19.4 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX92381.1 - 0.003 18.1 0.0 0.011 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 ORX92381.1 - 0.032 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3640 PF12342.8 ORX92381.1 - 0.032 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) Hydin_ADK PF17213.3 ORX92381.1 - 0.15 12.3 0.5 9 6.5 0.0 2.2 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 ORX92381.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase HMG_box PF00505.19 ORX92382.1 - 3.4e-19 69.0 1.3 4.2e-19 68.7 1.3 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX92382.1 - 1.4e-11 44.8 0.7 1.8e-11 44.4 0.7 1.2 1 0 0 1 1 1 1 HMG-box domain dCMP_cyt_deam_1 PF00383.23 ORX92383.1 - 1.1e-13 50.9 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ORX92383.1 - 5.3e-08 33.1 1.8 1e-07 32.3 0.2 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ORX92383.1 - 0.0035 17.0 0.3 1.2 8.7 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Iso_dh PF00180.20 ORX92384.1 - 2.3e-102 342.7 0.1 2.7e-102 342.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IMS PF00817.20 ORX92385.1 - 8.7e-41 139.4 0.0 1.5e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 ORX92385.1 - 8e-12 44.5 0.2 1.9e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 ORX92385.1 - 1.1e-08 35.7 0.0 1.2e-07 32.4 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORX92385.1 - 0.00014 22.0 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PTS_EIIA_2 PF00359.22 ORX92385.1 - 0.13 12.2 0.1 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 LPD38 PF18857.1 ORX92385.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 Myticin-prepro PF10690.9 ORX92389.1 - 0.0016 18.7 0.3 0.0027 17.9 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel p450 PF00067.22 ORX92392.1 - 4.6e-75 253.1 0.0 6.5e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 ORX92393.1 - 2.3e-37 128.6 0.0 2.6e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Furin-like_2 PF15913.5 ORX92398.1 - 0.016 15.3 3.9 0.024 14.8 3.9 1.2 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich NAD_binding_1 PF00175.21 ORX92399.1 - 8.9e-34 116.4 0.0 1.4e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORX92399.1 - 1.1e-23 83.4 0.0 5.8e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORX92399.1 - 2.3e-10 40.8 0.0 2e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain COPI_C PF06957.11 ORX92400.1 - 2.4e-107 359.2 0.0 3.7e-107 358.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 ORX92400.1 - 2.2e-102 343.4 0.0 3.2e-102 342.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 ORX92400.1 - 1.3e-45 152.4 19.4 3.6e-07 30.8 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92400.1 - 1.9e-11 44.1 0.1 0.00022 21.5 0.0 5.6 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX92400.1 - 0.21 10.2 4.0 0.68 8.5 0.3 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Prok-RING_1 PF14446.6 ORX92400.1 - 0.57 10.2 5.3 1.4 8.9 5.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 60KD_IMP PF02096.20 ORX92401.1 - 2.2e-26 92.7 0.4 3e-26 92.3 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein TPT PF03151.16 ORX92402.1 - 2.2e-33 115.9 19.1 2.8e-33 115.5 19.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORX92402.1 - 1.4e-05 25.2 31.0 6.9e-05 23.0 17.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORX92402.1 - 6.8e-05 22.2 18.8 8.8e-05 21.9 18.8 1.1 1 0 0 1 1 1 1 UAA transporter family ADH_N PF08240.12 ORX92403.1 - 4.3e-31 107.0 1.4 7.4e-31 106.3 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX92403.1 - 1.6e-21 76.7 0.0 2.6e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORX92403.1 - 1.9e-10 40.6 0.0 8.4e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORX92403.1 - 6.6e-09 36.9 0.0 1.5e-08 35.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX92403.1 - 0.00051 19.4 0.1 0.00082 18.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 ORX92403.1 - 0.015 16.0 0.0 0.035 14.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ADH_N_assoc PF13823.6 ORX92403.1 - 0.044 13.7 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.18 ORX92403.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PAP2_C PF14360.6 ORX92404.1 - 1.5e-15 57.4 11.8 1.5e-15 57.4 11.8 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORX92404.1 - 2.3e-07 30.6 6.9 2.3e-07 30.6 6.9 1.7 2 1 0 2 2 2 1 PAP2 superfamily TRIQK PF15168.6 ORX92404.1 - 7.5 6.5 5.2 3.8 7.5 0.1 2.7 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Cytochrom_C1 PF02167.15 ORX92405.1 - 2.6e-97 324.8 0.0 3.1e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORX92405.1 - 0.0004 20.6 0.0 0.00077 19.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORX92405.1 - 0.0014 19.7 0.0 0.0062 17.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c PIP5K PF01504.18 ORX92406.1 - 4.4e-102 341.0 0.3 8.1e-102 340.1 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MCU PF04678.13 ORX92407.1 - 4.4e-30 105.1 0.0 6.5e-30 104.5 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial calcium uniporter Med9 PF07544.13 ORX92407.1 - 0.18 11.9 0.9 0.59 10.3 0.2 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BTB PF00651.31 ORX92408.1 - 9e-17 61.3 1.8 1.2e-15 57.6 0.7 2.6 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 ORX92408.1 - 3.4e-05 24.0 0.1 6.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 MATH domain ACR_tran PF00873.19 ORX92408.1 - 0.2 9.3 0.0 0.27 8.9 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Cyclin_N PF00134.23 ORX92409.1 - 6.4e-10 38.9 0.1 7e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin PF08613.11 ORX92409.1 - 5.9e-06 26.7 0.6 2.2e-05 24.9 0.6 2.0 1 1 0 1 1 1 1 Cyclin Herpes_U15 PF05613.11 ORX92409.1 - 5.8 7.7 5.9 44 4.8 0.3 3.3 2 1 0 3 3 3 0 Human herpesvirus U15 protein PGP_phosphatase PF09419.10 ORX92410.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase SET PF00856.28 ORX92411.1 - 1.8e-07 31.7 0.1 2e-05 25.0 0.1 2.7 2 1 0 2 2 2 1 SET domain MFS_1 PF07690.16 ORX92412.1 - 6.5e-40 137.1 32.5 8.1e-40 136.8 32.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribonuclease_T2 PF00445.18 ORX92413.1 - 2.5e-36 125.6 0.1 3.6e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Uricase PF01014.18 ORX92414.1 - 2.5e-63 212.2 2.4 2.4e-35 121.7 1.0 2.0 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORX92415.1 - 1.8e-60 202.9 3.4 2.4e-36 124.9 2.0 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORX92415.1 - 0.0019 18.7 1.0 0.026 15.1 0.6 2.3 2 0 0 2 2 2 1 Dihydroneopterin aldolase Collagen PF01391.18 ORX92416.1 - 5.7e-05 22.8 21.9 0.00013 21.7 21.9 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_transf_10 PF00852.19 ORX92423.1 - 1.4e-45 155.2 0.8 2e-45 154.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 ORX92423.1 - 1.6e-11 44.6 1.1 1.3e-10 41.7 0.1 2.5 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal Transferase PF02458.15 ORX92424.1 - 1.3e-60 205.3 0.0 1.5e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Transferase family Solute_trans_a PF03619.16 ORX92425.1 - 9.6e-97 323.6 11.9 1.2e-96 323.4 11.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1462 PF07315.11 ORX92425.1 - 0.015 15.5 0.1 0.031 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Nairovirus_M PF07948.11 ORX92425.1 - 0.25 9.5 0.9 0.35 9.0 0.9 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Septin PF00735.18 ORX92426.1 - 7e-79 265.0 0.0 8.6e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 ORX92426.1 - 3.1e-05 23.6 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX92426.1 - 4.9e-05 23.4 0.0 8.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORX92426.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 ORX92426.1 - 0.013 15.4 0.3 0.14 12.1 0.2 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 ORX92426.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX92426.1 - 0.027 14.8 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX92426.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORX92426.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3884 PF13024.6 ORX92426.1 - 0.17 11.4 0.0 2.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3884) Pkinase PF00069.25 ORX92427.1 - 1.1e-72 244.5 0.0 1.7e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92427.1 - 6.8e-33 114.0 0.0 1.3e-32 113.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX92427.1 - 0.00038 19.9 0.3 0.76 9.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 ORX92427.1 - 0.057 13.3 0.0 0.3 11.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C2H2_11 PF16622.5 ORX92428.1 - 0.055 13.2 0.9 0.12 12.2 0.4 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2013 PF09431.10 ORX92429.1 - 4.2e-45 153.3 0.3 4.2e-45 153.3 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Ras PF00071.22 ORX92430.1 - 4.5e-33 114.1 0.0 4.9e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX92430.1 - 4e-26 91.6 0.0 4.4e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX92430.1 - 1.6e-08 34.2 0.0 1.7e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX92430.1 - 0.074 12.4 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 ORX92431.1 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 ORX92431.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.2 1 1 0 1 1 1 0 RsgA GTPase DUF836 PF05768.14 ORX92432.1 - 4.6e-15 55.8 0.0 5.2e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 ORX92432.1 - 0.00024 21.2 0.0 0.00053 20.2 0.0 1.6 1 1 1 2 2 2 1 Glutaredoxin TraF PF13728.6 ORX92432.1 - 0.015 15.1 0.0 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 ORX92432.1 - 0.031 14.7 0.0 0.047 14.1 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1223 PF06764.11 ORX92432.1 - 0.064 13.3 0.0 0.35 10.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) Mo-co_dimer PF03404.16 ORX92432.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF350 PF03994.14 ORX92433.1 - 0.067 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) FPN1 PF06963.12 ORX92434.1 - 2.1e-106 356.1 15.7 2.3e-106 356.0 15.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) adh_short PF00106.25 ORX92445.1 - 3.1e-24 85.5 0.0 1.5e-23 83.3 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX92445.1 - 1.6e-18 67.1 0.0 2.1e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX92445.1 - 4.7e-09 36.4 0.6 1.4e-08 34.8 0.6 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX92445.1 - 0.00041 20.3 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX92445.1 - 0.0097 15.4 0.0 0.065 12.7 0.0 2.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family STAT_int PF02865.17 ORX92445.1 - 0.034 14.6 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 STAT protein, protein interaction domain Peptidase_M14 PF00246.24 ORX92446.1 - 3.1e-79 266.8 0.5 3.7e-79 266.5 0.5 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_M14 PF00246.24 ORX92447.1 - 1.1e-76 258.5 0.2 1.3e-76 258.2 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORX92447.1 - 0.0024 18.3 1.0 0.011 16.1 0.2 2.5 3 0 0 3 3 3 1 Carboxypeptidase activation peptide EF-hand_1 PF00036.32 ORX92448.1 - 4.8e-27 91.5 6.9 1.5e-06 27.3 0.0 5.8 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 ORX92448.1 - 7.6e-27 93.6 2.7 3.1e-10 40.4 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORX92448.1 - 6.8e-23 78.6 5.3 1.6e-07 30.7 0.2 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 ORX92448.1 - 5.4e-20 71.0 0.1 6e-09 35.6 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORX92448.1 - 3.4e-19 67.4 0.6 0.00011 21.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORX92448.1 - 0.0013 19.0 0.1 0.33 11.3 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 ORX92448.1 - 0.01 15.8 2.6 1.1 9.1 0.0 3.5 1 1 2 4 4 4 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 ORX92448.1 - 0.14 12.5 0.8 0.4 11.0 0.3 2.0 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region IF2_N PF04760.15 ORX92448.1 - 0.23 11.3 0.0 0.56 10.1 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region SBF_like PF13593.6 ORX92449.1 - 2.1e-82 276.9 20.0 2.4e-82 276.8 20.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) THOC2_N PF16134.5 ORX92450.1 - 1.3e-164 549.4 0.1 2.8e-164 548.3 0.1 1.6 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 ORX92450.1 - 2.4e-100 335.7 0.3 9.1e-100 333.7 0.3 2.1 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 ORX92450.1 - 1.2e-32 111.7 0.0 3.2e-32 110.4 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PPR_2 PF13041.6 ORX92451.1 - 6.4e-116 378.5 42.3 1.4e-16 60.4 0.2 14.1 5 2 10 15 15 14 13 PPR repeat family PPR PF01535.20 ORX92451.1 - 1.1e-93 301.2 17.9 1.6e-07 31.1 0.0 15.8 15 1 0 15 15 15 13 PPR repeat PPR_1 PF12854.7 ORX92451.1 - 4e-93 304.8 13.5 1.7e-09 37.2 0.0 15.4 15 0 0 15 15 15 14 PPR repeat PPR_3 PF13812.6 ORX92451.1 - 5.7e-77 253.7 55.8 6.7e-11 42.1 0.3 10.3 3 1 10 14 14 14 13 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX92451.1 - 1.7e-41 142.0 5.5 7e-11 41.9 0.0 5.9 1 1 5 6 6 6 5 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 ORX92451.1 - 9.8e-11 41.5 4.4 0.012 15.4 0.0 5.6 2 1 3 5 5 5 3 Mitochondrial ATPase expression TPR_14 PF13428.6 ORX92451.1 - 6.8e-09 35.8 0.0 2.4 9.2 0.0 9.2 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92451.1 - 1e-07 32.3 0.3 5.3 7.6 0.0 6.9 6 2 3 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92451.1 - 3.4e-07 29.8 6.6 1.4 8.9 0.0 7.4 9 0 0 9 9 8 2 Tetratricopeptide repeat Clathrin PF00637.20 ORX92451.1 - 2.1e-06 27.7 14.8 0.87 9.5 0.4 6.6 4 2 2 6 6 5 2 Region in Clathrin and VPS MRP-S27 PF10037.9 ORX92451.1 - 4.2e-05 22.6 13.5 0.12 11.2 0.1 4.8 4 1 1 5 5 5 2 Mitochondrial 28S ribosomal protein S27 BTAD PF03704.17 ORX92451.1 - 0.00028 21.3 0.1 0.022 15.2 0.1 3.2 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 ORX92451.1 - 0.00051 19.9 0.1 47 4.3 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92451.1 - 0.00072 19.8 3.0 1.6 9.0 0.0 5.1 6 1 0 6 6 5 1 Tetratricopeptide repeat Prp18 PF02840.15 ORX92451.1 - 0.00079 19.5 3.5 0.072 13.1 0.0 3.7 3 0 0 3 3 3 1 Prp18 domain RPN7 PF10602.9 ORX92451.1 - 0.0015 18.3 2.5 6.9 6.3 0.0 5.1 6 0 0 6 6 6 1 26S proteasome subunit RPN7 YfiO PF13525.6 ORX92451.1 - 0.0047 16.7 4.9 2.3 7.9 0.2 4.1 2 1 2 4 4 4 2 Outer membrane lipoprotein RPM2 PF08579.11 ORX92451.1 - 0.011 16.1 19.5 2.8 8.4 0.5 6.2 3 1 2 5 5 4 0 Mitochondrial ribonuclease P subunit (RPM2) Vps23_core PF09454.10 ORX92451.1 - 0.012 15.5 2.6 12 5.9 0.0 5.1 2 1 3 5 5 5 0 Vps23 core domain TPR_2 PF07719.17 ORX92451.1 - 0.04 14.0 7.6 38 4.7 0.1 6.5 8 0 0 8 8 5 0 Tetratricopeptide repeat Fer2_2 PF01799.20 ORX92451.1 - 0.07 13.2 0.1 0.61 10.1 0.2 2.8 3 1 0 3 3 2 0 [2Fe-2S] binding domain TPR_8 PF13181.6 ORX92451.1 - 2.5 8.5 6.1 19 5.8 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 ORX92452.1 - 1.6e-35 122.5 0.0 1.9e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PRC PF05239.16 ORX92453.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 PRC-barrel domain Ribosomal_S11 PF00411.19 ORX92453.1 - 0.019 15.4 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S11 FMN_red PF03358.15 ORX92454.1 - 1.4e-13 50.8 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 ORX92454.1 - 0.00014 22.1 0.2 0.00071 19.8 0.2 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 ORX92454.1 - 0.00024 20.9 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DNA_methylase PF00145.17 ORX92454.1 - 0.04 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF3597 PF12200.8 ORX92454.1 - 2.9 8.4 5.1 6.1 7.4 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Rrn6 PF10214.9 ORX92454.1 - 9.7 4.5 10.1 13 4.1 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Abhydrolase_3 PF07859.13 ORX92455.1 - 8.1e-59 199.0 0.0 9.4e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX92455.1 - 1.4e-08 34.1 0.2 6.8e-08 31.8 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORX92455.1 - 5.1e-05 22.8 0.0 0.00028 20.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 ORX92455.1 - 0.00018 21.1 0.0 0.057 13.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 ORX92455.1 - 0.001 17.8 0.0 0.025 13.2 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ORX92455.1 - 0.0025 17.4 0.0 0.062 12.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 ORX92455.1 - 0.052 12.4 0.4 0.27 10.1 0.4 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.9 ORX92455.1 - 0.077 12.5 0.2 0.52 9.8 0.1 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.20 ORX92455.1 - 0.094 12.3 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Putative esterase YtkA PF13115.6 ORX92455.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 YtkA-like Chlorophyllase PF07224.11 ORX92455.1 - 0.16 11.0 0.1 0.4 9.7 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase p450 PF00067.22 ORX92456.1 - 6.1e-81 272.5 0.1 8e-81 272.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_A2B PF12384.8 ORX92457.1 - 0.044 13.3 0.0 0.15 11.6 0.0 1.7 1 1 1 2 2 2 0 Ty3 transposon peptidase DAO PF01266.24 ORX92458.1 - 2.8e-36 125.9 0.0 3.3e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX92458.1 - 2.3e-07 30.9 0.1 4.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX92458.1 - 7.9e-05 21.9 0.2 0.00015 21.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORX92458.1 - 8.6e-05 23.0 0.1 0.00027 21.4 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORX92458.1 - 0.00019 21.9 0.0 0.00045 20.6 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ORX92458.1 - 0.0003 20.1 0.0 0.00073 18.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORX92458.1 - 0.00057 19.2 0.2 0.00091 18.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORX92458.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 ORX92458.1 - 0.00093 18.1 0.6 0.19 10.5 0.7 2.2 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 ORX92458.1 - 0.0011 18.1 0.3 0.0018 17.5 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ORX92458.1 - 0.0015 17.9 0.1 0.017 14.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORX92458.1 - 0.0035 16.1 0.0 0.0065 15.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 ORX92458.1 - 0.033 13.6 0.1 0.13 11.6 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX92458.1 - 0.033 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORX92458.1 - 0.042 13.5 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RNA_pol_Rpb2_6 PF00562.28 ORX92458.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Peptidase_M3 PF01432.20 ORX92466.1 - 1.7e-137 459.5 3.6 1.7e-137 459.5 3.6 1.5 2 0 0 2 2 2 1 Peptidase family M3 DUF3106 PF11304.8 ORX92466.1 - 0.5 10.9 3.2 0.59 10.6 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) START PF01852.19 ORX92467.1 - 5.3e-17 61.9 0.0 7.1e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 START domain DUF1533 PF07550.11 ORX92467.1 - 0.034 14.0 0.4 2.2 8.3 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1533) Cadherin-like PF12733.7 ORX92467.1 - 0.16 12.5 0.4 4.4 7.9 0.4 2.5 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain EVE PF01878.18 ORX92468.1 - 1.3e-50 171.2 0.0 1.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 EVE domain DUF3248 PF11609.8 ORX92468.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) SH3_2 PF07653.17 ORX92469.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1844 PF08899.11 ORX92470.1 - 0.14 12.4 0.8 0.49 10.7 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) DUF2514 PF10721.9 ORX92470.1 - 0.27 11.3 4.6 1 9.4 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.19 ORX92470.1 - 0.29 9.0 12.3 0.21 9.5 6.9 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family HAP1_N PF04849.13 ORX92470.1 - 0.73 9.0 40.9 0.34 10.1 24.4 4.1 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF1054 PF06335.12 ORX92470.1 - 8.8 6.2 9.1 0.76 9.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) Pkinase PF00069.25 ORX92471.1 - 2e-69 233.9 0.0 3e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92471.1 - 5.4e-50 170.1 0.0 8.7e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ORX92471.1 - 2.7e-20 72.5 0.1 7.6e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 ORX92471.1 - 1.9e-16 60.2 0.1 3.5e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORX92471.1 - 2.3e-14 53.3 0.6 6.4e-14 51.8 0.2 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 ORX92471.1 - 6e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 ORX92471.1 - 9.3e-06 25.2 0.0 0.00012 21.6 0.0 2.4 3 0 0 3 3 3 1 Kinase-like SAM_PNT PF02198.16 ORX92471.1 - 3.3e-05 23.8 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 ORX92471.1 - 0.0043 16.8 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 ORX92471.1 - 0.006 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 ORX92471.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 ORX92471.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORX92471.1 - 0.22 11.4 0.1 1.5 8.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 ORX92472.1 - 4.5e-08 33.6 15.1 0.023 15.6 4.7 7.9 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92472.1 - 0.00024 21.3 0.1 50 4.3 0.0 5.8 6 2 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_1 PF03029.17 ORX92473.1 - 4.2e-83 278.8 0.6 4.2e-83 278.8 0.6 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORX92473.1 - 4.3e-06 26.4 2.8 7e-06 25.7 0.1 2.5 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 ORX92473.1 - 8.7e-06 25.6 0.0 2.3e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 ORX92473.1 - 2e-05 24.2 0.1 0.00035 20.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B SRP54 PF00448.22 ORX92473.1 - 8.2e-05 22.3 0.0 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 ORX92473.1 - 8.5e-05 22.8 0.0 0.00055 20.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 ORX92473.1 - 0.0001 22.5 0.1 0.0003 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORX92473.1 - 0.00011 22.3 0.0 0.0005 20.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ORX92473.1 - 0.00011 21.8 0.1 0.0015 18.2 0.1 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORX92473.1 - 0.00022 20.3 0.2 0.15 11.0 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 ORX92473.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORX92473.1 - 0.0013 19.2 0.1 0.0036 17.7 0.0 1.7 2 2 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 ORX92473.1 - 0.0018 17.5 0.0 0.0055 15.9 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 ORX92473.1 - 0.0024 17.6 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORX92473.1 - 0.0025 17.8 0.0 0.97 9.3 0.0 2.4 2 0 0 2 2 2 1 NTPase G-alpha PF00503.20 ORX92473.1 - 0.0031 16.7 4.5 0.11 11.6 0.0 2.9 2 2 1 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 ORX92473.1 - 0.0034 17.3 0.1 3.8 7.4 0.0 3.3 3 1 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 ORX92473.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 ORX92473.1 - 0.012 15.5 0.0 0.18 11.6 0.0 2.4 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PhoH PF02562.16 ORX92473.1 - 0.013 15.0 0.0 0.2 11.1 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein AAA_23 PF13476.6 ORX92473.1 - 0.013 16.0 0.2 2.3 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORX92473.1 - 0.014 15.1 0.0 0.06 13.1 0.0 2.1 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 ORX92473.1 - 0.015 14.6 0.1 0.054 12.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 ORX92473.1 - 0.017 15.0 2.0 0.024 14.5 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 ORX92473.1 - 0.02 14.6 0.1 0.47 10.2 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 ORX92473.1 - 0.021 15.1 0.1 0.053 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 ORX92473.1 - 0.032 13.9 1.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase KAP_NTPase PF07693.14 ORX92473.1 - 0.034 13.4 1.2 0.51 9.5 1.2 2.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_31 PF13614.6 ORX92473.1 - 0.044 13.7 0.0 3.1 7.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 ORX92473.1 - 0.046 13.9 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ORX92473.1 - 0.054 14.0 0.1 0.22 12.1 0.0 2.1 2 1 1 3 3 2 0 AAA domain TsaE PF02367.17 ORX92473.1 - 0.06 13.3 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MipZ PF09140.11 ORX92473.1 - 0.064 12.5 0.2 0.17 11.1 0.0 1.8 2 1 0 2 2 2 0 ATPase MipZ APS_kinase PF01583.20 ORX92473.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Arf PF00025.21 ORX92473.1 - 0.072 12.5 0.8 3.9 6.9 0.0 3.1 3 2 0 3 3 3 0 ADP-ribosylation factor family AAA PF00004.29 ORX92473.1 - 0.12 12.8 0.9 12 6.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fumerase PF05681.14 ORX92473.1 - 0.31 10.4 2.0 6.5 6.1 0.5 2.2 2 1 0 2 2 2 0 Fumarate hydratase (Fumerase) SUV3_C PF12513.8 ORX92474.1 - 2.3e-19 69.0 0.6 1.1e-18 66.8 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 ORX92474.1 - 2.8e-15 55.9 0.1 6.5e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 ORX92474.1 - 4.8e-13 49.4 0.0 1.1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LD_cluster3 PF18180.1 ORX92474.1 - 0.0014 18.3 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 SLOG cluster3 family Ion_trans_2 PF07885.16 ORX92475.1 - 4.9e-31 106.5 31.2 2.8e-17 62.5 12.7 3.3 4 0 0 4 4 4 2 Ion channel Lig_chan PF00060.26 ORX92475.1 - 0.00016 21.5 6.8 0.043 13.7 3.2 2.7 1 1 1 2 2 2 2 Ligand-gated ion channel Ion_trans PF00520.31 ORX92475.1 - 0.00093 18.5 20.2 0.025 13.8 3.4 2.8 2 1 0 2 2 2 2 Ion transport protein FAM176 PF14851.6 ORX92475.1 - 0.031 13.9 3.0 0.12 12.0 1.0 2.6 2 1 0 2 2 2 0 FAM176 family TetR_C_24 PF17932.1 ORX92475.1 - 0.064 13.5 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ctr PF04145.15 ORX92475.1 - 0.079 13.6 3.4 3.2 8.4 0.0 3.1 2 1 0 2 2 2 0 Ctr copper transporter family DUF3810 PF12725.7 ORX92475.1 - 2 7.7 10.3 0.035 13.5 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) IRK PF01007.20 ORX92475.1 - 2.6 7.8 18.9 0.17 11.7 4.5 3.9 3 2 1 4 4 4 0 Inward rectifier potassium channel transmembrane domain Holin_SPP1 PF04688.13 ORX92475.1 - 5 7.4 6.5 25 5.1 0.1 3.4 3 0 0 3 3 3 0 SPP1 phage holin RdRP PF05183.12 ORX92476.1 - 1.5e-184 614.9 0.0 1.9e-184 614.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Guanylate_kin PF00625.21 ORX92476.1 - 0.039 13.7 0.4 0.63 9.7 0.1 2.3 2 0 0 2 2 2 0 Guanylate kinase Gti1_Pac2 PF09729.9 ORX92477.1 - 4.3e-47 160.5 3.0 5.9e-41 140.5 0.6 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family GPP34 PF05719.11 ORX92479.1 - 5.4e-59 199.6 0.2 7.3e-59 199.2 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PPR_2 PF13041.6 ORX92480.1 - 1.1e-120 393.7 41.0 1.2e-14 54.2 0.1 14.3 2 1 13 15 15 15 13 PPR repeat family PPR PF01535.20 ORX92480.1 - 6.9e-81 261.0 27.2 5.8e-08 32.5 0.0 14.4 14 0 0 14 14 14 13 PPR repeat PPR_3 PF13812.6 ORX92480.1 - 3.5e-80 264.0 17.6 1.1e-13 51.0 0.2 9.3 6 2 2 9 9 9 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX92480.1 - 4.7e-69 227.7 5.1 4.9e-06 26.1 0.0 14.1 14 0 0 14 14 14 11 PPR repeat PPR_long PF17177.4 ORX92480.1 - 1.4e-49 168.3 17.3 2.4e-14 53.2 0.8 6.7 1 1 5 6 6 6 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX92480.1 - 5.1e-10 39.8 14.0 0.28 11.6 1.6 8.0 1 1 4 6 6 6 3 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX92480.1 - 3e-08 32.9 8.5 0.32 9.8 0.1 5.5 1 1 6 7 7 7 4 Mitochondrial 28S ribosomal protein S27 TPR_7 PF13176.6 ORX92480.1 - 2.2e-06 27.3 4.8 1.1 9.4 0.0 7.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX92480.1 - 8.3e-05 23.1 0.8 69 4.7 0.0 7.6 7 2 2 10 10 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92480.1 - 0.00015 21.4 0.6 0.32 10.9 0.2 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat 7TMR-HDED PF07697.11 ORX92480.1 - 0.0002 21.6 3.3 0.037 14.1 0.0 3.1 2 1 1 3 3 3 2 7TM-HD extracellular DUF1897 PF09005.10 ORX92480.1 - 0.0055 16.2 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) DUF4817 PF16087.5 ORX92480.1 - 0.0091 15.8 0.0 21 5.0 0.0 4.3 3 1 1 4 4 4 0 Helix-turn-helix domain (DUF4817) TrmE_N PF10396.9 ORX92480.1 - 0.027 14.8 0.5 88 3.5 0.0 4.7 3 1 2 5 5 5 0 GTP-binding protein TrmE N-terminus RST PF12174.8 ORX92480.1 - 0.031 14.2 0.5 11 6.0 0.0 4.3 4 0 0 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain RPN7 PF10602.9 ORX92480.1 - 0.082 12.6 8.9 8.1 6.1 0.0 5.5 3 2 1 5 5 5 0 26S proteasome subunit RPN7 AAA_17 PF13207.6 ORX92480.1 - 0.19 12.1 0.6 21 5.5 0.1 4.0 2 2 2 4 4 4 0 AAA domain TPR_10 PF13374.6 ORX92480.1 - 0.24 11.3 3.0 10 6.2 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat 2C_adapt PF08793.10 ORX92480.1 - 0.34 11.1 1.1 87 3.4 0.1 4.1 4 0 0 4 4 4 0 2-cysteine adaptor domain RhoGAP-FF1 PF16512.5 ORX92480.1 - 0.81 10.4 8.1 2.2 9.0 0.0 5.4 6 4 2 8 8 7 0 p190-A and -B Rho GAPs FF domain TPR_6 PF13174.6 ORX92480.1 - 6.9 7.5 7.7 72 4.3 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Prp18 PF02840.15 ORX92480.1 - 7 6.7 10.0 6.2 6.9 0.2 3.7 3 1 1 4 4 4 0 Prp18 domain DUF676 PF05057.14 ORX92484.1 - 3.1e-32 111.9 0.0 1.4e-31 109.7 0.0 2.0 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ORX92484.1 - 0.016 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Zds_C PF08632.10 ORX92485.1 - 1.4e-22 79.1 0.9 2.6e-22 78.3 0.9 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ribosomal_S4e PF00900.20 ORX92486.1 - 3.8e-36 122.8 0.1 8.1e-36 121.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX92486.1 - 5.1e-27 93.3 0.1 9.4e-27 92.4 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 ORX92486.1 - 1.3e-08 34.4 0.1 2.9e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 S4 domain RS4NT PF08071.12 ORX92486.1 - 4.9e-08 32.9 0.1 1.2e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 ORX92486.1 - 4e-05 23.4 7.7 6.5e-05 22.7 5.4 2.6 2 0 0 2 2 2 1 KOW motif Ank_2 PF12796.7 ORX92487.1 - 0.0081 16.7 0.1 0.39 11.4 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX92487.1 - 0.05 14.2 1.7 47 5.0 0.0 5.5 5 1 1 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 ORX92487.1 - 0.083 13.5 0.2 57 4.4 0.0 4.8 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX92488.1 - 0.081 13.5 0.4 84 4.3 0.1 4.9 3 1 1 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 ORX92490.1 - 0.024 15.2 0.1 4 8.1 0.0 3.8 3 1 1 4 4 4 0 Ankyrin repeats (3 copies) PHY PF00360.20 ORX92491.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region Ank_4 PF13637.6 ORX92491.1 - 0.14 12.8 0.1 54 4.5 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Radical_SAM PF04055.21 ORX92501.1 - 7e-31 107.8 0.1 1.3e-30 107.0 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ORX92501.1 - 1.2e-30 105.4 0.0 2.7e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 ORX92501.1 - 4.6e-06 26.5 0.0 2.1e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 TRAM domain DHHC PF01529.20 ORX92502.1 - 2.4e-34 118.3 3.9 2.4e-34 118.3 3.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Wzy_C PF04932.15 ORX92502.1 - 0.74 9.4 3.8 0.31 10.7 0.1 2.0 2 1 0 2 2 2 0 O-Antigen ligase DUF1775 PF07987.11 ORX92503.1 - 2.2e-36 125.4 0.0 2.6e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) DUF1775 PF07987.11 ORX92504.1 - 6.2e-40 136.9 0.1 7.8e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) CsbD PF05532.12 ORX92505.1 - 1.2e-19 69.9 21.2 1.1e-10 41.3 5.5 2.0 1 1 1 2 2 2 2 CsbD-like DNA_pol_B_palm PF14792.6 ORX92507.1 - 9e-31 106.4 0.0 1.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORX92507.1 - 2.5e-21 75.6 0.1 4.4e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORX92507.1 - 4.6e-21 74.4 0.1 8.7e-21 73.5 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORX92507.1 - 1.3e-14 54.3 0.6 4.8e-14 52.5 0.6 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 ORX92507.1 - 0.027 15.1 0.0 11 6.7 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Glyco_hydro_9 PF00759.19 ORX92508.1 - 2.8e-124 415.7 2.8 3.2e-124 415.5 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 F-box-like PF12937.7 ORX92509.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 F-box-like DUF1279 PF06916.13 ORX92510.1 - 1.6e-19 70.3 0.2 2.4e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ubie_methyltran PF01209.18 ORX92512.1 - 4e-15 55.8 0.0 1e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORX92512.1 - 1.2e-13 51.5 0.0 2.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX92512.1 - 3.6e-12 46.8 0.0 6.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92512.1 - 6e-12 45.6 0.0 1.6e-11 44.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX92512.1 - 3e-09 36.9 0.0 4.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX92512.1 - 0.003 18.3 0.0 0.0059 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX92512.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF4564 PF15169.6 ORX92512.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Fe-S_biosyn PF01521.20 ORX92512.1 - 0.15 12.3 0.2 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 Iron-sulphur cluster biosynthesis p450 PF00067.22 ORX92513.1 - 7.4e-73 245.9 0.1 3e-72 243.9 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ORX92520.1 - 0.00017 21.7 10.5 0.00028 21.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORX92521.1 - 6.3e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ORX92521.1 - 2.8e-12 46.7 0.0 6.4e-12 45.6 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORX92521.1 - 1.8e-09 37.8 0.0 7.7e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 PAS domain PAS_11 PF14598.6 ORX92521.1 - 2.9e-07 30.6 0.0 5.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX92521.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORX92521.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 PAS domain Tyrosinase PF00264.20 ORX92522.1 - 1e-34 120.8 6.1 1.4e-33 117.0 6.1 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase PAP2_3 PF14378.6 ORX92523.1 - 1.2e-22 80.6 8.3 1.2e-22 80.6 8.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ORX92523.1 - 3.2e-08 33.4 3.8 3.2e-08 33.4 3.8 2.1 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 ORX92523.1 - 0.38 11.3 7.2 0.075 13.6 2.6 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Fe_hyd_lg_C PF02906.14 ORX92524.1 - 6.9e-70 235.5 0.0 7.3e-69 232.1 0.0 2.1 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 ORX92524.1 - 3.1e-08 33.6 0.0 6.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.12 ORX92524.1 - 0.059 13.3 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD synthetase tRNA_bind PF01588.20 ORX92525.1 - 3.6e-28 97.5 0.0 4.9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Metallophos PF00149.28 ORX92527.1 - 3.3e-15 57.1 1.3 5.4e-15 56.4 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Asparaginase PF00710.20 ORX92528.1 - 7.3e-62 208.3 0.0 1.4e-61 207.4 0.0 1.5 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORX92528.1 - 1.6e-30 105.6 0.0 3.1e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 ORX92528.1 - 4.8e-27 94.4 0.9 1.5e-13 51.2 0.2 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX92528.1 - 9.2e-26 89.9 2.4 9e-08 32.5 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORX92528.1 - 6.1e-24 83.4 1.3 3.3e-08 33.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ORX92528.1 - 6e-20 71.1 0.8 2.8e-08 33.9 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX92528.1 - 1.1e-19 68.4 0.3 0.00011 22.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat DrsE PF02635.15 ORX92528.1 - 0.12 12.8 0.1 9.5 6.6 0.0 2.6 2 0 0 2 2 2 0 DsrE/DsrF-like family zf-DNL PF05180.12 ORX92528.1 - 0.16 11.9 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 DNL zinc finger GTP-bdg_M PF16360.5 ORX92529.1 - 0.024 15.2 0.6 2 9.1 0.1 2.5 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Tmemb_cc2 PF10267.9 ORX92529.1 - 0.11 11.6 0.7 0.2 10.8 0.7 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Tmemb_9 PF05434.11 ORX92529.1 - 1.2 9.1 4.8 2.5 8.0 0.3 3.0 4 0 0 4 4 4 0 TMEM9 zf-C2H2 PF00096.26 ORX92530.1 - 2.5e-11 43.4 8.7 1.6e-05 25.1 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX92530.1 - 2.5e-09 37.2 7.7 0.00013 22.5 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX92530.1 - 5.7e-09 36.1 0.8 4.1e-05 23.8 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX92530.1 - 2.3e-07 30.9 1.3 0.00032 20.9 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORX92530.1 - 2.8e-07 30.7 1.1 2.8e-07 30.7 1.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX92530.1 - 3.2e-06 27.0 3.1 0.00038 20.4 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 ORX92530.1 - 0.0022 18.0 2.3 0.37 10.9 0.1 2.2 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 ORX92530.1 - 0.005 17.1 2.2 0.036 14.4 0.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 ORX92530.1 - 0.049 13.7 1.2 0.063 13.4 0.2 1.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Zn_ribbon_SprT PF17283.2 ORX92530.1 - 0.099 12.6 1.9 0.099 12.6 1.9 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 ORX92530.1 - 0.11 12.3 8.9 0.37 10.6 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 ORX92530.1 - 0.47 10.6 4.0 2 8.6 0.9 2.1 1 1 1 2 2 2 0 Zinc ribbon domain GAGA PF09237.11 ORX92530.1 - 5.8 6.8 7.5 11 5.9 3.4 2.1 1 1 1 2 2 2 0 GAGA factor Peptidase_M20 PF01546.28 ORX92531.1 - 5.8e-22 78.4 0.2 6.1e-21 75.1 0.2 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORX92531.1 - 1.4e-21 76.4 0.1 3.3e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORX92531.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M28 Cyclin PF08613.11 ORX92532.1 - 7.5e-11 42.7 0.0 1.1e-10 42.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX92532.1 - 4.4e-09 36.1 0.2 7e-09 35.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain E1-E2_ATPase PF00122.20 ORX92533.1 - 5.6e-51 172.6 3.4 5.6e-51 172.6 3.4 3.5 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92533.1 - 4.1e-23 82.8 0.2 2e-22 80.5 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92533.1 - 3.4e-14 52.3 0.3 1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF5362 PF17319.2 ORX92533.1 - 0.015 15.1 6.3 0.39 10.6 0.3 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Cation_ATPase PF13246.6 ORX92533.1 - 0.04 14.0 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX92533.1 - 0.091 12.5 0.1 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX92533.1 - 0.54 9.9 26.8 0.12 12.0 14.2 3.0 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORX92534.1 - 5.6e-51 172.6 3.4 5.6e-51 172.6 3.4 3.5 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92534.1 - 4e-23 82.8 0.2 2e-22 80.5 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92534.1 - 3.4e-14 52.3 0.3 1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF5362 PF17319.2 ORX92534.1 - 0.015 15.1 6.3 0.39 10.6 0.3 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Cation_ATPase PF13246.6 ORX92534.1 - 0.04 14.0 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX92534.1 - 0.09 12.5 0.1 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX92534.1 - 0.54 9.9 26.8 0.12 12.0 14.2 3.0 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Glyco_hydro_46 PF01374.18 ORX92535.1 - 1.2e-35 123.1 0.0 1.4e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Virul_fac_BrkB PF03631.15 ORX92536.1 - 0.01 15.5 4.6 0.024 14.2 4.6 1.7 1 0 0 1 1 1 0 Virulence factor BrkB 7tm_1 PF00001.21 ORX92536.1 - 0.087 12.1 3.7 0.1 11.9 3.7 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 ORX92536.1 - 0.12 11.7 7.2 0.54 9.6 7.2 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Dicty_CAR PF05462.11 ORX92536.1 - 0.49 9.5 10.2 0.063 12.4 5.8 1.7 3 0 0 3 3 3 0 Slime mold cyclic AMP receptor Arf PF00025.21 ORX92537.1 - 3.2e-78 261.2 0.1 3.6e-78 261.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX92537.1 - 6.3e-16 58.7 0.1 8.3e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX92537.1 - 1.1e-13 51.1 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORX92537.1 - 1.4e-12 47.4 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORX92537.1 - 1.5e-12 47.3 1.1 5.3e-08 32.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORX92537.1 - 6.1e-10 38.8 0.0 7.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX92537.1 - 0.00013 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX92537.1 - 0.0015 17.9 0.4 0.0023 17.3 0.1 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase MobB PF03205.14 ORX92537.1 - 0.054 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CTP_transf_1 PF01148.20 ORX92538.1 - 0.019 14.7 2.6 0.025 14.4 2.6 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family DUF3902 PF13042.6 ORX92538.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Pkinase PF00069.25 ORX92539.1 - 2.5e-61 207.4 0.0 2.8e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92539.1 - 4.4e-33 114.6 0.0 5.3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX92539.1 - 2.7e-07 29.7 0.1 3.2e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORX92539.1 - 1.7e-06 27.5 0.2 2.6e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX92539.1 - 3.3e-06 26.6 0.0 5.3e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX92539.1 - 0.045 13.7 0.7 0.47 10.3 0.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 ORX92539.1 - 0.067 12.7 0.3 0.13 11.8 0.3 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2573 PF10835.8 ORX92539.1 - 0.13 12.6 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) GSHPx PF00255.19 ORX92540.1 - 1.8e-46 156.2 1.1 2.4e-46 155.8 1.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORX92540.1 - 2e-06 27.7 0.1 3.5e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX92540.1 - 0.00036 20.3 0.1 0.0017 18.1 0.1 1.9 1 1 0 1 1 1 1 Redoxin MCU PF04678.13 ORX92541.1 - 1.5e-35 122.9 0.2 2.2e-35 122.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter RTX_C PF08339.10 ORX92541.1 - 0.011 15.8 0.2 4.4 7.3 0.0 2.5 3 0 0 3 3 3 0 RTX C-terminal domain N_formyltrans_C PF18216.1 ORX92541.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Pkinase PF00069.25 ORX92543.1 - 2.8e-74 249.8 0.0 3.2e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92543.1 - 1.4e-44 152.3 0.0 1.7e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX92543.1 - 4.2e-08 32.8 0.2 6e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX92543.1 - 8e-06 25.4 0.0 0.00085 18.7 0.0 2.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORX92543.1 - 4.6e-05 22.4 0.0 6.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX92543.1 - 8.5e-05 21.7 1.5 0.00018 20.6 1.5 1.5 1 1 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 ORX92543.1 - 0.021 14.3 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 ORX92543.1 - 0.054 13.4 0.0 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1681 PF07933.14 ORX92556.1 - 6.5e-59 197.9 0.0 7.7e-59 197.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Tyrosinase PF00264.20 ORX92557.1 - 1.1e-34 120.7 10.5 5.3e-33 115.2 9.2 2.6 2 1 0 2 2 2 1 Common central domain of tyrosinase PMT PF02366.18 ORX92558.1 - 6.1e-84 281.4 14.8 1.3e-83 280.4 14.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX92558.1 - 7.5e-56 188.9 12.7 7.5e-56 188.9 12.7 2.8 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX92558.1 - 2.8e-31 108.8 0.1 6.7e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 MIR domain PMT PF02366.18 ORX92559.1 - 2.7e-77 259.7 13.9 2.7e-77 259.7 13.9 1.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX92559.1 - 4.5e-55 186.3 16.1 4.5e-55 186.3 16.1 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX92559.1 - 3.5e-28 98.7 1.5 5.7e-28 98.0 1.5 1.2 1 0 0 1 1 1 1 MIR domain WLM PF08325.10 ORX92560.1 - 1.4e-44 152.4 0.1 2.4e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 ORX92560.1 - 8.2e-14 51.1 0.1 2.5e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORX92560.1 - 0.00013 22.4 0.1 0.00057 20.3 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 ORX92560.1 - 0.0012 19.2 0.0 0.0059 16.9 0.0 2.2 2 1 1 3 3 3 1 Ubiquitin-like domain SprT-like PF10263.9 ORX92560.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 SprT-like family TBK1_ULD PF18396.1 ORX92560.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 ORX92560.1 - 0.067 13.8 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF45 PF01863.17 ORX92560.1 - 0.069 13.2 4.6 0.094 12.7 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF45 Rad60-SLD PF11976.8 ORX92560.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glycos_transf_1 PF00534.20 ORX92561.1 - 5.1e-12 45.7 0.0 1.3e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX92561.1 - 2.2e-10 41.1 0.0 1.1e-09 38.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORX92561.1 - 1.4e-08 34.9 0.0 2.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORX92561.1 - 7.2e-07 29.8 0.0 5.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ORX92561.1 - 5.9e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CCDC24 PF15669.5 ORX92561.1 - 0.1 12.5 0.1 0.67 9.8 0.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family CK2S PF15011.6 ORX92562.1 - 0.00011 22.1 2.4 0.005 16.7 0.2 2.2 1 1 1 2 2 2 2 Casein Kinase 2 substrate RapA_C PF12137.8 ORX92562.1 - 0.002 17.2 0.1 0.0024 17.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal CHDCT2 PF08074.11 ORX92562.1 - 0.0024 18.1 0.5 0.0041 17.3 0.2 1.5 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Septin PF00735.18 ORX92563.1 - 2.3e-120 401.1 0.3 2.3e-120 401.1 0.3 2.0 1 1 1 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORX92563.1 - 9.7e-08 32.1 0.3 3.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX92563.1 - 5.7e-05 23.1 8.3 0.00081 19.3 0.3 3.7 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ORX92563.1 - 0.00036 20.8 0.0 0.004 17.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX92563.1 - 0.0011 19.4 0.0 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 ORX92563.1 - 0.0025 17.2 0.0 0.0025 17.2 0.0 2.5 2 1 0 2 2 1 1 AIG1 family AAA_23 PF13476.6 ORX92563.1 - 0.0049 17.4 8.6 3.8 8.0 9.8 2.3 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 ORX92563.1 - 0.0073 15.9 0.6 0.02 14.5 0.0 2.1 2 0 0 2 2 1 1 Ras family AAA_29 PF13555.6 ORX92563.1 - 0.0075 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 ORX92563.1 - 0.011 15.9 0.1 0.036 14.3 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORX92563.1 - 0.017 14.6 9.6 0.022 14.3 0.0 3.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Exonuc_VII_L PF02601.15 ORX92563.1 - 0.032 13.8 5.7 0.052 13.1 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.6 ORX92563.1 - 0.036 13.8 0.5 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORX92563.1 - 0.039 14.5 0.5 0.039 14.5 0.5 2.8 1 1 0 2 2 2 0 ABC transporter DUF87 PF01935.17 ORX92563.1 - 0.062 13.4 6.8 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 ORX92563.1 - 0.069 12.9 0.4 2.9 7.6 0.1 3.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2703 PF10865.8 ORX92563.1 - 0.11 12.7 2.0 0.35 11.1 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) RNA_helicase PF00910.22 ORX92563.1 - 0.14 12.6 0.0 0.6 10.5 0.0 2.1 2 0 0 2 2 1 0 RNA helicase FapA PF03961.13 ORX92563.1 - 0.35 9.4 9.8 0.52 8.9 9.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Dynamin_N PF00350.23 ORX92563.1 - 1.4 8.9 12.6 1.8 8.6 0.1 3.6 2 2 1 3 3 2 0 Dynamin family Sds3 PF08598.11 ORX92563.1 - 2 8.4 15.2 4.2 7.3 15.2 1.5 1 0 0 1 1 1 0 Sds3-like Atg14 PF10186.9 ORX92563.1 - 2.8 6.9 11.8 5.5 6.0 11.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 ORX92563.1 - 4.5 6.4 9.8 7.8 5.6 9.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein AAA_11 PF13086.6 ORX92563.1 - 8.8 6.0 9.7 12 5.6 8.4 1.8 2 0 0 2 2 2 0 AAA domain ABC1 PF03109.16 ORX92564.1 - 6.6e-34 116.6 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 ORX92564.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain BAG PF02179.16 ORX92565.1 - 7.6e-11 42.3 0.2 2.4e-10 40.7 0.2 1.9 1 0 0 1 1 1 1 BAG domain IQ PF00612.27 ORX92565.1 - 0.07 13.0 1.6 0.16 11.9 1.6 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif NIF PF03031.18 ORX92568.1 - 9.5e-14 51.4 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glycoprotein_G PF00802.19 ORX92569.1 - 2.4 7.5 9.5 2.5 7.4 9.5 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G CS PF04969.16 ORX92570.1 - 1.3e-10 42.1 0.2 2.8e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 CS domain Aa_trans PF01490.18 ORX92571.1 - 8.9e-63 212.4 39.5 1e-62 212.2 39.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX92571.1 - 5.8e-05 22.1 26.9 5.8e-05 22.1 26.9 1.8 1 1 0 1 1 1 1 Spore germination protein OppC_N PF12911.7 ORX92571.1 - 1 9.4 0.0 1 9.4 0.0 4.8 6 0 0 6 6 6 0 N-terminal TM domain of oligopeptide transport permease C Diphthami_syn_2 PF01902.17 ORX92572.1 - 1.9e-33 115.8 0.0 3.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 ORX92572.1 - 3.1e-26 91.7 0.0 2.1e-12 47.1 0.0 3.4 3 0 0 3 3 3 3 Endoribonuclease L-PSP DUF4817 PF16087.5 ORX92572.1 - 0.023 14.5 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) PINIT PF14324.6 ORX92573.1 - 9.5e-27 94.1 0.0 2e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 ORX92573.1 - 7.9e-22 76.8 4.5 1.4e-21 75.9 4.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORX92573.1 - 5.3e-06 26.2 2.7 5.8e-06 26.0 1.1 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 ORX92573.1 - 0.00076 19.2 0.1 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 SAP domain Exo_endo_phos_2 PF14529.6 ORX92573.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Prok-RING_4 PF14447.6 ORX92573.1 - 0.13 12.2 2.7 0.28 11.1 1.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-met PF12874.7 ORX92573.1 - 0.14 12.6 0.2 0.44 11.0 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-RING_2 PF13639.6 ORX92573.1 - 1.4 9.3 5.1 3.2 8.1 5.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 ORX92573.1 - 1.8 8.4 4.8 9.5 6.2 5.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2418 PF10332.9 ORX92574.1 - 2.6e-24 85.6 1.7 2.6e-24 85.6 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Pho86 PF11124.8 ORX92575.1 - 0.18 11.3 4.3 3.9 6.8 1.4 2.8 2 1 0 2 2 2 0 Inorganic phosphate transporter Pho86 Acyl-CoA_dh_1 PF00441.24 ORX92576.1 - 7.8e-35 120.3 2.0 1e-34 119.9 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORX92576.1 - 2.3e-23 82.2 0.0 4e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORX92576.1 - 1.1e-15 58.2 0.0 1.8e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORX92576.1 - 3e-12 46.9 1.4 4.7e-12 46.3 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORX92576.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal FPN1 PF06963.12 ORX92577.1 - 9.2e-125 416.6 21.2 1e-124 416.4 21.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PMT PF02366.18 ORX92577.1 - 0.00028 20.6 2.4 0.00028 20.6 2.4 3.3 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Flu_NS1 PF00600.19 ORX92578.1 - 0.034 13.7 0.0 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Influenza non-structural protein (NS1) MTABC_N PF16185.5 ORX92578.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Sec8_exocyst PF04048.14 ORX92580.1 - 5e-37 127.0 3.2 5e-37 127.0 3.2 3.7 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 ORX92580.1 - 0.00017 21.0 10.6 0.00017 21.0 10.6 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 ORX92580.1 - 0.12 12.5 10.4 0.071 13.2 2.8 3.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 ORX92580.1 - 2.9 7.6 4.8 2.9 7.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Hemerythrin PF01814.23 ORX92580.1 - 9.3 6.9 7.7 6.5 7.4 0.0 3.9 4 1 0 4 4 4 0 Hemerythrin HHE cation binding domain Phosphodiest PF01663.22 ORX92581.1 - 6.3e-13 49.0 0.4 5.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 ORX92581.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily SYS1 PF09801.9 ORX92581.1 - 0.4 10.8 12.7 0.95 9.6 2.6 3.1 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network TIP41 PF04176.13 ORX92582.1 - 5.1e-65 218.1 0.1 6.5e-65 217.8 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family Apolipoprotein PF01442.18 ORX92583.1 - 1.5e-09 38.0 11.9 3e-08 33.8 6.6 2.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 ORX92583.1 - 7.4e-08 32.8 39.7 0.033 14.7 12.5 6.8 1 1 4 5 5 5 2 YtxH-like protein DUF883 PF05957.13 ORX92583.1 - 1e-07 32.4 22.0 0.0014 19.1 1.1 6.2 1 1 5 6 6 6 3 Bacterial protein of unknown function (DUF883) MAPEG PF01124.18 ORX92583.1 - 0.00015 21.7 0.0 0.0005 20.0 0.0 2.0 1 0 0 1 1 1 1 MAPEG family ApoO PF09769.9 ORX92583.1 - 0.035 14.1 14.4 54 3.7 0.0 5.4 2 2 1 3 3 3 0 Apolipoprotein O Phasin PF05597.11 ORX92583.1 - 0.051 13.6 26.0 0.16 12.0 1.2 5.2 4 1 2 6 6 6 0 Poly(hydroxyalcanoate) granule associated protein (phasin) LHC PF00556.20 ORX92583.1 - 0.12 12.5 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Plug PF07715.15 ORX92583.1 - 0.13 12.8 1.1 0.27 11.8 0.1 2.0 2 0 0 2 2 2 0 TonB-dependent Receptor Plug Domain ApoLp-III PF07464.11 ORX92583.1 - 2 8.5 14.8 0.24 11.5 7.5 3.0 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Oleosin PF01277.17 ORX92583.1 - 4.2 7.1 7.8 1.1 9.0 0.2 3.7 2 2 3 5 5 5 0 Oleosin DUF2367 PF10164.9 ORX92584.1 - 5e-11 43.0 11.6 3.8e-10 40.2 11.6 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Auto_anti-p27 PF06677.12 ORX92585.1 - 7.8e-33 112.4 6.6 4.2e-16 58.8 0.7 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4187 PF13821.6 ORX92585.1 - 0.0046 16.7 0.6 0.017 14.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_jaz PF12171.8 ORX92585.1 - 0.013 15.8 4.5 0.017 15.4 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TFIIIC PF12660.7 ORX92585.1 - 0.73 9.8 5.0 42 4.2 5.0 2.2 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex IBR PF01485.21 ORX92585.1 - 2.1 8.6 9.0 2 8.7 1.0 2.9 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain ABC2_membrane_3 PF12698.7 ORX92586.1 - 5e-25 88.3 16.2 7.9e-25 87.7 16.2 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 ORX92586.1 - 2.7e-22 79.8 0.0 4.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX92586.1 - 1e-10 41.9 0.0 1.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 ORX92586.1 - 4.2e-07 29.6 17.5 4.2e-07 29.6 17.5 2.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 ORX92586.1 - 0.00017 20.9 1.9 0.00025 20.4 1.9 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX92586.1 - 0.005 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ORX92586.1 - 0.0098 15.6 0.0 4.4 6.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ORX92586.1 - 0.094 12.1 0.0 8.8 5.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX92586.1 - 0.1 12.4 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain LSR PF05624.14 ORX92587.1 - 1.5 8.9 11.0 0.99 9.4 4.6 2.3 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Cyclin PF08613.11 ORX92588.1 - 1.3e-13 51.6 0.0 1.5e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX92588.1 - 6.6e-08 32.4 0.0 9.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4806 PF16064.5 ORX92588.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) UBA_2 PF08587.11 ORX92589.1 - 0.13 12.4 0.1 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) PRiA4_ORF3 PF07929.11 ORX92590.1 - 4.3e-09 36.3 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein GPI-anchored PF10342.9 ORX92591.1 - 3.9e-12 46.8 0.6 1.3e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.22 ORX92592.1 - 5.3e-84 282.6 0.0 6.2e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORX92593.1 - 7.2e-44 150.3 0.0 8.5e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 ORX92594.1 - 0.0001 22.0 0.6 0.00024 20.9 0.1 1.9 2 0 0 2 2 2 1 F-box domain zf-C2H2 PF00096.26 ORX92595.1 - 1.1e-15 57.1 15.5 4.8e-05 23.6 1.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX92595.1 - 1.7e-10 40.8 14.5 0.00089 19.9 1.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX92595.1 - 3.5e-10 39.8 10.1 0.00045 20.5 0.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX92595.1 - 2.1e-07 30.8 9.2 0.062 13.3 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORX92595.1 - 0.00012 22.7 1.7 0.00033 21.3 0.9 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORX92595.1 - 0.00044 20.5 8.6 0.2 12.0 0.2 3.4 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORX92595.1 - 0.00072 19.3 0.5 0.00072 19.3 0.5 2.8 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-met PF12874.7 ORX92595.1 - 0.001 19.4 3.4 0.14 12.6 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX92595.1 - 0.0018 18.5 4.4 0.0018 18.5 4.4 2.6 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-MYST PF17772.1 ORX92595.1 - 0.028 14.0 4.9 1.2 8.8 0.2 2.8 2 1 1 3 3 3 0 MYST family zinc finger domain Zn-ribbon_8 PF09723.10 ORX92595.1 - 0.04 14.1 2.2 0.65 10.2 0.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 ORX92595.1 - 0.072 13.3 5.5 0.38 11.0 2.9 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain zf_C2H2_ZHX PF18387.1 ORX92595.1 - 0.094 12.4 2.4 0.69 9.6 0.3 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 ORX92595.1 - 0.21 12.0 5.2 0.068 13.6 1.5 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 ORX92595.1 - 0.29 11.2 2.9 13 6.0 0.7 2.6 2 0 0 2 2 2 0 XPA protein N-terminal LIM PF00412.22 ORX92595.1 - 0.45 10.8 7.0 3.4 8.0 0.3 2.7 2 1 1 3 3 3 0 LIM domain zf-AN1 PF01428.16 ORX92595.1 - 2.1 8.6 8.9 2.3 8.5 1.1 2.9 3 0 0 3 3 3 0 AN1-like Zinc finger TFIIS_C PF01096.18 ORX92595.1 - 2.3 8.1 5.9 6.6 6.7 0.2 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DNA_pol3_theta PF06440.11 ORX92596.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Tyrosinase PF00264.20 ORX92600.1 - 5.7e-11 43.1 1.2 7.2e-11 42.8 1.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2017 PF09438.10 ORX92602.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Tim17 PF02466.19 ORX92603.1 - 1.3e-32 112.5 5.5 1.6e-32 112.2 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AAA PF00004.29 ORX92604.1 - 2.6e-57 192.9 0.0 6.1e-43 146.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX92604.1 - 6e-09 35.6 1.0 2.4e-05 24.0 0.0 3.2 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 ORX92604.1 - 3.1e-07 30.9 0.4 0.014 15.8 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ORX92604.1 - 1.9e-05 24.5 0.0 0.00079 19.2 0.0 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX92604.1 - 7.4e-05 22.9 0.0 0.002 18.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 ORX92604.1 - 8.8e-05 22.4 0.1 0.0048 16.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 ORX92604.1 - 0.00023 21.4 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORX92604.1 - 0.00066 19.7 0.1 0.14 12.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORX92604.1 - 0.0019 18.5 0.5 0.047 13.9 0.1 3.3 3 1 1 4 4 3 1 AAA domain TsaE PF02367.17 ORX92604.1 - 0.0024 17.8 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORX92604.1 - 0.0031 17.2 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 ORX92604.1 - 0.0032 17.0 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 ORX92604.1 - 0.0034 16.5 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 ORX92604.1 - 0.005 16.1 0.1 0.042 13.1 0.0 2.3 3 0 0 3 3 3 1 TIP49 P-loop domain RNA_helicase PF00910.22 ORX92604.1 - 0.0053 17.1 0.0 0.067 13.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 ORX92604.1 - 0.0057 16.0 2.9 0.035 13.5 0.1 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ORX92604.1 - 0.012 15.0 0.0 0.063 12.6 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 ORX92604.1 - 0.015 15.9 0.0 0.076 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX92604.1 - 0.029 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX92604.1 - 0.042 13.4 0.3 0.26 10.9 0.1 2.3 2 1 1 3 3 2 0 AAA domain Sigma54_activat PF00158.26 ORX92604.1 - 0.047 13.4 0.0 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 ORX92604.1 - 0.058 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AMP-binding PF00501.28 ORX92605.1 - 7.3e-94 314.8 0.0 9.2e-94 314.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX92605.1 - 1.9e-23 83.2 0.1 1.6e-22 80.3 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORX92605.1 - 6.7e-22 77.2 0.1 1.6e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3613 PF12266.8 ORX92605.1 - 0.097 12.5 1.1 0.32 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Methyltransf_25 PF13649.6 ORX92606.1 - 2.4e-13 50.6 0.0 4.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92606.1 - 4.5e-12 46.0 0.0 6.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX92606.1 - 3.8e-10 40.3 0.0 1.2e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX92606.1 - 6.8e-10 39.6 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX92606.1 - 5.8e-05 23.0 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 ORX92606.1 - 0.00039 20.0 0.0 0.00078 19.0 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 ORX92606.1 - 0.0044 16.3 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 ORX92606.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 ORX92606.1 - 0.0075 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme KCH PF16944.5 ORX92608.1 - 5e-64 216.5 22.6 1e-63 215.4 22.6 1.5 1 1 0 1 1 1 1 Fungal potassium channel Form_Nir_trans PF01226.17 ORX92608.1 - 0.81 9.0 6.2 0.054 12.8 1.2 1.5 2 0 0 2 2 2 0 Formate/nitrite transporter PDZ_5 PF17817.1 ORX92609.1 - 0.00081 19.6 0.1 0.00098 19.4 0.1 1.1 1 0 0 1 1 1 1 PDZ domain ABC_tran PF00005.27 ORX92610.1 - 1e-07 32.5 0.0 3.7e-07 30.7 0.0 1.9 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 ORX92610.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein HLH PF00010.26 ORX92611.1 - 9.5e-14 51.1 0.2 2.2e-13 49.9 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 ORX92611.1 - 0.0081 16.6 2.4 0.21 12.1 0.1 2.3 2 0 0 2 2 2 1 Cell division protein ZapB TSC22 PF01166.18 ORX92611.1 - 0.022 15.0 0.3 0.055 13.8 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 ORX92611.1 - 0.025 14.7 0.2 0.025 14.7 0.2 2.2 3 0 0 3 3 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 ORX92611.1 - 0.072 13.1 2.2 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribonuc_L-PSP PF01042.21 ORX92612.1 - 8.1e-46 155.0 0.3 9.1e-46 154.8 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Homeodomain PF00046.29 ORX92613.1 - 1.2e-16 60.3 4.9 1.3e-16 60.2 4.9 1.0 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 ORX92613.1 - 0.012 15.4 0.0 0.023 14.6 0.0 1.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 ORX92613.1 - 0.092 12.7 1.2 0.22 11.5 0.3 1.8 2 0 0 2 2 2 0 Homeobox KN domain AMP-binding PF00501.28 ORX92614.1 - 1.9e-94 316.7 0.0 2.2e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Tub PF01167.18 ORX92615.1 - 4e-40 138.1 0.2 4.3e-40 138.0 0.2 1.0 1 0 0 1 1 1 1 Tub family Ank_2 PF12796.7 ORX92616.1 - 0.0001 22.8 0.4 0.0011 19.5 0.4 2.7 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX92616.1 - 0.0017 18.6 0.6 0.19 12.1 0.2 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX92616.1 - 0.0058 17.0 2.1 19 6.2 0.2 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 ORX92616.1 - 0.19 12.3 4.7 2.7 8.6 0.2 4.0 4 1 1 5 5 5 0 Ankyrin repeat PAP2 PF01569.21 ORX92617.1 - 1.9e-30 105.4 0.7 1.9e-30 105.4 0.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX92617.1 - 2.1e-06 27.6 6.0 1.4e-05 24.9 6.0 2.1 1 1 0 1 1 1 1 PAP2 superfamily UPF0016 PF01169.19 ORX92617.1 - 0.0052 17.1 1.2 5.3 7.5 0.7 3.4 2 1 1 3 3 3 1 Uncharacterized protein family UPF0016 MauE PF07291.11 ORX92617.1 - 0.041 13.7 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 Methylamine utilisation protein MauE DUF3159 PF11361.8 ORX92617.1 - 0.049 13.4 0.9 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3159) YibE_F PF07907.11 ORX92617.1 - 0.094 12.2 0.2 0.094 12.2 0.2 1.7 2 0 0 2 2 2 0 YibE/F-like protein Strabismus PF06638.11 ORX92617.1 - 0.17 10.5 0.2 1.2 7.7 0.7 1.8 1 1 1 2 2 2 0 Strabismus protein DUF202 PF02656.15 ORX92617.1 - 0.3 11.6 8.7 28 5.2 0.2 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) TMEMspv1-c74-12 PF11044.8 ORX92617.1 - 1.2 9.1 6.8 2.6 8.1 6.8 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GPI-anchored PF10342.9 ORX92618.1 - 3.3e-12 47.0 1.4 5.6e-12 46.3 1.4 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 ORX92620.1 - 2.4e-52 177.9 0.0 2.9e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92620.1 - 2.3e-23 82.8 0.1 3.1e-22 79.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase ABC1 PF03109.16 ORX92620.1 - 0.0089 16.2 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ORX92620.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORX92620.1 - 0.042 13.5 0.3 0.093 12.3 0.3 1.7 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 ORX92620.1 - 0.091 12.1 0.0 7.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Oxidored_FMN PF00724.20 ORX92622.1 - 5e-77 259.5 0.0 6.4e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ORX92622.1 - 0.2 10.7 0.0 2.5 7.1 0.0 2.4 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) Questin_oxidase PF14027.6 ORX92632.1 - 1.2e-63 215.7 0.0 1.5e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like PSD2 PF07624.11 ORX92632.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Sen15 PF09631.10 ORX92633.1 - 6e-24 84.2 0.0 7.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein Response_reg PF00072.24 ORX92634.1 - 2.4e-22 79.2 0.0 2.3e-16 59.9 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain DSPc PF00782.20 ORX92635.1 - 6.9e-31 106.8 0.3 2.2e-27 95.5 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX92635.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORX92635.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 ORX92635.1 - 0.054 13.8 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 ORX92635.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Elong-fact-P_C PF09285.11 ORX92635.1 - 0.15 11.8 0.3 18 5.2 0.0 2.7 3 0 0 3 3 3 0 Elongation factor P, C-terminal PSP1 PF04468.12 ORX92636.1 - 8.4e-35 118.9 2.3 1.4e-34 118.2 2.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region SGL PF08450.12 ORX92637.1 - 4.8e-27 95.1 0.1 1.2e-25 90.5 0.1 2.3 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 ORX92637.1 - 0.00087 19.2 1.3 3.4 7.9 0.1 4.3 4 0 0 4 4 4 1 NHL repeat Arylesterase PF01731.20 ORX92637.1 - 0.029 14.6 0.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Arylesterase SBBP PF06739.11 ORX92637.1 - 0.045 13.8 2.8 12 6.0 0.0 3.8 4 0 0 4 4 4 0 Beta-propeller repeat SdiA-regulated PF06977.11 ORX92637.1 - 0.12 11.6 0.0 6.3 6.0 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated Reg_prop PF07494.11 ORX92637.1 - 0.15 12.4 1.2 27 5.4 0.2 4.2 4 0 0 4 4 4 0 Two component regulator propeller RRM_1 PF00076.22 ORX92638.1 - 1.3e-83 274.8 1.6 8.3e-20 70.4 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORX92638.1 - 1.9e-29 101.6 0.6 6.4e-29 99.9 0.5 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORX92638.1 - 1.7e-12 47.0 0.5 0.046 13.3 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX92638.1 - 1.8e-06 27.7 0.0 0.01 15.7 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX92638.1 - 0.00025 21.1 0.8 5.5 7.2 0.1 5.1 3 2 1 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 ORX92638.1 - 0.00029 20.8 4.9 0.22 11.6 0.9 4.0 4 0 0 4 4 4 1 RNA binding motif YflT PF11181.8 ORX92638.1 - 0.0022 18.5 1.5 1.2 9.7 1.9 2.9 2 0 0 2 2 2 1 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 ORX92638.1 - 0.016 15.2 0.9 10 6.2 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 ORX92638.1 - 0.016 14.8 0.1 24 4.7 0.0 3.6 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated DUF4523 PF15023.6 ORX92638.1 - 0.023 14.5 0.0 19 5.0 0.0 3.7 2 2 0 4 4 4 0 Protein of unknown function (DUF4523) RRM_8 PF11835.8 ORX92638.1 - 0.085 13.1 0.0 30 4.9 0.0 3.2 3 0 0 3 3 3 0 RRM-like domain NOP5NT PF08156.13 ORX92638.1 - 0.099 13.0 1.2 11 6.4 0.3 3.4 3 0 0 3 3 3 0 NOP5NT (NUC127) domain Phage_holin_Dp1 PF16938.5 ORX92639.1 - 0.19 12.0 0.1 0.32 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative phage holin Dp-1 Aa_trans PF01490.18 ORX92640.1 - 3.3e-31 108.4 30.6 5.6e-31 107.7 30.6 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein S_4TM PF18159.1 ORX92640.1 - 8.4 5.6 7.2 22 4.2 1.1 2.5 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain GPI-anchored PF10342.9 ORX92652.1 - 0.00099 19.8 0.1 0.0016 19.2 0.1 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TMEM132D_N PF15705.5 ORX92652.1 - 0.034 14.0 0.0 0.32 10.8 0.0 2.3 1 1 2 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term SusE PF14292.6 ORX92652.1 - 0.12 12.6 0.4 0.19 12.0 0.4 1.3 1 0 0 1 1 1 0 SusE outer membrane protein PX PF00787.24 ORX92654.1 - 3.1e-23 81.9 2.3 8.8e-23 80.5 2.3 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ORX92654.1 - 3.3e-12 46.5 11.2 1.2e-08 34.8 4.8 2.5 2 0 0 2 2 2 2 Vps5 C terminal like DUF19 PF01579.18 ORX92654.1 - 0.017 14.9 0.6 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF19) DUF1664 PF07889.12 ORX92654.1 - 0.056 13.5 4.0 7.2 6.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Acylphosphatase PF00708.18 ORX92654.1 - 0.86 10.0 2.4 2.9 8.4 0.0 2.9 4 0 0 4 4 4 0 Acylphosphatase T4SS PF07996.11 ORX92654.1 - 0.92 9.9 7.4 14 6.0 0.2 3.5 3 0 0 3 3 3 0 Type IV secretion system proteins SLX9 PF15341.6 ORX92654.1 - 3.6 8.0 14.5 6.3 7.2 3.7 3.4 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 Sec8_exocyst PF04048.14 ORX92654.1 - 4.2 7.3 9.4 7.3 6.5 0.8 3.4 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain zf-C2H2_4 PF13894.6 ORX92656.1 - 0.0028 18.3 1.9 0.17 12.8 0.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX92656.1 - 0.0073 16.7 3.5 0.01 16.2 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type Vif PF00559.17 ORX92656.1 - 0.024 14.3 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein zf-C2H2_aberr PF17017.5 ORX92656.1 - 0.033 14.3 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Aberrant zinc-finger DUF2110 PF09883.9 ORX92656.1 - 0.089 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Baculo_p33 PF05214.12 ORX92657.1 - 0.087 12.6 3.4 0.13 12.0 0.8 2.6 2 0 0 2 2 2 0 Baculovirus P33 UPF0184 PF03670.13 ORX92657.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) E1-E2_ATPase PF00122.20 ORX92659.1 - 3.9e-44 150.3 2.0 3.9e-44 150.3 2.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92659.1 - 5.2e-19 69.4 0.1 2.9e-18 66.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92659.1 - 1.7e-10 40.4 0.0 4.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92659.1 - 0.0038 17.0 0.5 0.0071 16.1 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORX92660.1 - 3.4e-23 82.1 7.5 1.2e-16 60.8 0.0 3.9 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 ORX92660.1 - 3.3e-19 70.0 0.1 1.4e-18 67.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX92660.1 - 0.0034 17.2 0.6 0.0062 16.3 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92660.1 - 0.067 12.9 0.2 2.5 7.9 0.0 2.5 1 1 1 2 2 2 0 Cation transporter/ATPase, N-terminus FixP_N PF14715.6 ORX92660.1 - 8.5 6.2 10.7 14 5.5 1.6 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP E1-E2_ATPase PF00122.20 ORX92661.1 - 1.7e-42 145.0 3.7 1.7e-42 145.0 3.7 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92661.1 - 1.2e-14 55.1 0.1 2.2e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92661.1 - 5.4e-10 38.8 0.0 1.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92661.1 - 0.005 16.6 0.2 0.01 15.6 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92661.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX92662.1 - 2.6e-42 144.4 3.5 2.6e-42 144.4 3.5 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92662.1 - 6.6e-19 69.0 0.2 4.9e-18 66.2 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92662.1 - 6e-10 38.7 0.0 1.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92662.1 - 0.0035 17.1 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92662.1 - 0.075 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX92663.1 - 1.7e-42 145.0 3.7 1.7e-42 145.0 3.7 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92663.1 - 4.9e-19 69.5 0.3 3.9e-18 66.5 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92663.1 - 5.5e-10 38.8 0.0 1.5e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92663.1 - 0.0032 17.2 0.1 0.0067 16.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92663.1 - 0.067 13.3 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX92664.1 - 2.6e-42 144.4 3.0 2.6e-42 144.4 3.0 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92664.1 - 2.7e-19 70.3 0.3 2.2e-18 67.3 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92664.1 - 1e-09 37.9 0.0 2.9e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92664.1 - 0.003 17.3 0.1 0.0065 16.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92664.1 - 0.066 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX92665.1 - 1.6e-42 145.1 3.7 1.6e-42 145.1 3.7 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92665.1 - 6.8e-19 69.0 0.2 5.5e-18 66.0 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92665.1 - 6e-10 38.7 0.0 1.7e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92665.1 - 0.0033 17.2 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92665.1 - 0.075 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) HpaB PF03241.13 ORX92665.1 - 0.68 9.0 3.2 0.41 9.7 0.1 2.1 3 0 0 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase C terminal E1-E2_ATPase PF00122.20 ORX92666.1 - 1.9e-43 148.1 2.6 1.9e-43 148.1 2.6 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92666.1 - 9.4e-19 68.5 0.1 5.8e-18 65.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92666.1 - 1e-11 44.4 0.0 2.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92666.1 - 0.0036 17.1 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92666.1 - 0.07 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX92667.1 - 1.4e-43 148.6 2.5 1.4e-43 148.6 2.5 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92667.1 - 2.4e-18 67.2 0.3 1.9e-17 64.2 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92667.1 - 1e-05 25.1 0.1 6.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92667.1 - 0.0035 17.1 0.1 0.007 16.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX92667.1 - 0.025 14.7 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Sigma_reg_N PF13800.6 ORX92667.1 - 2.3 8.6 4.9 27 5.1 0.1 2.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal E1-E2_ATPase PF00122.20 ORX92668.1 - 1.1e-43 148.8 8.1 1.9e-42 144.8 4.5 3.0 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 ORX92668.1 - 1.6e-18 67.8 0.1 7.8e-18 65.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX92668.1 - 1.3e-12 47.2 0.0 3.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX92668.1 - 0.01 15.6 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase OAD_gamma PF04277.13 ORX92668.1 - 3.1 8.4 7.1 6.9 7.3 2.4 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain ADH_N PF08240.12 ORX92669.1 - 4.6e-28 97.3 4.5 7.8e-28 96.5 4.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX92669.1 - 3e-18 66.1 0.1 8.5e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX92669.1 - 0.00043 21.4 0.0 0.00075 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX92669.1 - 0.047 13.0 0.2 0.086 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 ORX92669.1 - 0.06 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 ORX92669.1 - 0.08 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-CXXC PF02008.20 ORX92669.1 - 3.1 7.9 7.8 1.7 8.7 2.7 2.3 2 0 0 2 2 2 0 CXXC zinc finger domain PhoD PF09423.10 ORX92670.1 - 2.3e-111 372.2 7.8 2.8e-111 371.9 7.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORX92670.1 - 6e-32 110.0 0.1 1.3e-31 109.0 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ORX92670.1 - 3.5e-06 27.5 0.2 9.1e-06 26.2 0.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain p450 PF00067.22 ORX92671.1 - 3.6e-84 283.1 0.1 4.1e-84 283.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Baculo_PEP_C PF04513.12 ORX92672.1 - 0.0028 17.7 8.5 0.76 9.8 0.1 4.0 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 ORX92672.1 - 0.026 14.3 0.6 0.026 14.3 0.6 4.0 3 1 1 4 4 4 0 Family with sequence similarity 184, A and B Gp-FAR-1 PF05823.12 ORX92672.1 - 0.051 13.9 11.0 1.1 9.6 0.8 3.6 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Filament PF00038.21 ORX92672.1 - 0.22 11.1 18.8 0.38 10.3 3.8 3.8 4 1 0 4 4 4 0 Intermediate filament protein DUF489 PF04356.12 ORX92672.1 - 0.25 11.3 6.0 0.27 11.2 1.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF489) Prominin PF05478.11 ORX92672.1 - 1.5 6.7 10.1 0.38 8.7 1.3 3.0 2 1 0 3 3 3 0 Prominin DNA_photolyase PF00875.18 ORX92672.1 - 2.4 8.1 5.5 22 5.0 0.3 3.3 2 1 1 3 3 3 0 DNA photolyase Csm1_N PF18504.1 ORX92672.1 - 5.2 7.5 9.3 0.47 10.8 1.0 3.6 2 1 1 3 3 3 0 Csm1 N-terminal domain ADIP PF11559.8 ORX92672.1 - 9 6.4 11.4 15 5.6 3.3 2.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Aldedh PF00171.22 ORX92673.1 - 9.4e-135 449.7 0.0 1.1e-134 449.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORX92673.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) BLOC1S3 PF15753.5 ORX92673.1 - 0.022 14.9 0.1 0.047 13.8 0.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DASH_Dam1 PF08653.10 ORX92674.1 - 2.9e-12 46.2 0.1 5.7e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 Hexokinase_2 PF03727.16 ORX92675.1 - 7e-75 251.5 0.1 1.1e-74 250.9 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX92675.1 - 9.8e-66 221.5 0.0 1.7e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase MPC PF03650.13 ORX92677.1 - 6.7e-42 142.1 0.3 7.2e-42 142.0 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers UPF0242 PF06785.11 ORX92677.1 - 0.045 13.9 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0160 PF03690.13 ORX92677.1 - 0.065 12.9 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF5360 PF17314.2 ORX92677.1 - 0.089 12.9 0.8 0.11 12.6 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5360) GATA PF00320.27 ORX92678.1 - 4.1e-14 51.9 7.7 4.9e-14 51.6 6.3 1.8 2 0 0 2 2 2 1 GATA zinc finger zf-C2H2_3 PF13878.6 ORX92678.1 - 0.14 12.0 0.5 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO iPGM_N PF06415.13 ORX92679.1 - 8e-78 260.8 0.0 1.1e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 ORX92679.1 - 2.7e-77 259.5 0.0 3.1e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 ORX92679.1 - 0.00021 21.0 0.0 0.00046 19.9 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase OST3_OST6 PF04756.13 ORX92679.1 - 0.14 11.5 0.4 0.22 10.8 0.4 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Alk_phosphatase PF00245.20 ORX92679.1 - 0.15 11.0 0.0 0.4 9.6 0.0 1.7 2 0 0 2 2 2 0 Alkaline phosphatase Sulfatase PF00884.23 ORX92679.1 - 0.16 11.3 0.0 0.42 10.0 0.0 1.7 1 1 1 2 2 2 0 Sulfatase Glyco_hydro_18 PF00704.28 ORX92680.1 - 8.9e-26 91.3 1.3 3.2e-25 89.5 1.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_2 PF00553.19 ORX92680.1 - 0.0013 19.0 0.0 0.0045 17.3 0.0 1.9 1 0 0 1 1 1 1 Cellulose binding domain NIF PF03031.18 ORX92683.1 - 2e-55 186.9 0.1 2.7e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORX92683.1 - 0.011 16.1 0.2 0.1 13.0 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Cpn60_TCP1 PF00118.24 ORX92684.1 - 1.1e-171 571.9 4.7 1.2e-171 571.6 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_2 PF03142.15 ORX92685.1 - 9.3e-254 842.9 1.1 1.3e-253 842.4 1.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX92685.1 - 5.9e-13 49.2 0.0 5.3e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX92685.1 - 9.1e-11 42.0 8.9 4.2e-10 39.9 8.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 YfhO PF09586.10 ORX92685.1 - 0.0053 15.1 0.1 0.0083 14.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Glycos_transf_2 PF00535.26 ORX92685.1 - 0.042 13.6 0.0 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX92685.1 - 0.073 12.5 0.0 9.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 FGGY_N PF00370.21 ORX92686.1 - 2.4e-74 250.0 0.1 3.3e-74 249.5 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ORX92686.1 - 4.2e-69 232.2 0.9 7.4e-69 231.5 0.9 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain TGT PF01702.18 ORX92687.1 - 3.7e-84 282.9 0.0 4.5e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ank_2 PF12796.7 ORX92689.1 - 3.5e-15 56.4 2.4 7.5e-08 32.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TIG PF01833.24 ORX92689.1 - 1.8e-13 50.4 0.9 7.7e-13 48.3 0.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 ORX92689.1 - 2e-10 40.7 1.4 1.5e-06 28.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX92689.1 - 2.9e-10 40.5 0.1 7.9e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORX92689.1 - 6.9e-07 29.4 0.3 0.037 14.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORX92689.1 - 7.6e-07 29.0 0.1 0.0073 16.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat WD40 PF00400.32 ORX92690.1 - 1.3e-14 54.3 11.9 0.00014 22.6 0.2 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92690.1 - 1.2e-08 35.2 0.0 0.38 11.1 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX92690.1 - 0.0003 20.7 0.2 0.0076 16.1 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX92690.1 - 0.074 12.0 0.1 0.18 10.7 0.1 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DCAF15_WD40 PF14939.6 ORX92691.1 - 0.017 14.8 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat DEAD PF00270.29 ORX92692.1 - 1.1e-37 129.5 0.3 2.3e-37 128.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX92692.1 - 6.5e-27 94.1 0.3 6.2e-26 90.9 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX92692.1 - 4.5e-08 33.3 0.0 8.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORX92692.1 - 0.00052 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PK PF00224.21 ORX92693.1 - 3.9e-167 555.5 1.2 4.9e-167 555.1 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX92693.1 - 1.8e-36 124.9 0.0 5.8e-36 123.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX92693.1 - 3.9e-05 22.9 0.2 0.00021 20.5 0.0 2.0 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 ORX92693.1 - 0.04 12.9 0.0 0.53 9.2 0.0 2.4 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PK PF00224.21 ORX92694.1 - 3.8e-167 555.5 1.2 4.9e-167 555.1 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORX92694.1 - 1.8e-36 124.9 0.1 5.8e-36 123.3 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORX92694.1 - 3.9e-05 22.9 0.2 0.00021 20.5 0.0 2.0 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 ORX92694.1 - 0.039 13.0 0.2 0.53 9.2 0.0 2.5 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain ARID PF01388.21 ORX92695.1 - 0.0023 18.6 0.0 0.017 15.8 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 ORX92695.1 - 0.005 16.2 0.2 0.08 12.2 0.2 2.4 1 1 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa HMA PF00403.26 ORX92696.1 - 3.5e-62 206.7 10.2 1.6e-15 57.3 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 ORX92696.1 - 4.7e-47 159.8 2.3 1.1e-46 158.7 1.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORX92696.1 - 4.6e-43 147.9 0.1 7.3e-43 147.3 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX92696.1 - 0.0011 18.8 3.2 0.0031 17.3 0.8 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 ORX92696.1 - 0.0048 17.2 6.0 12 6.4 0.1 4.7 4 0 0 4 4 4 2 BFD-like [2Fe-2S] binding domain PUB PF09409.10 ORX92696.1 - 0.036 14.0 0.0 35 4.4 0.0 3.7 4 0 0 4 4 4 0 PUB domain RRM_3 PF08777.11 ORX92696.1 - 0.2 11.7 0.0 24 5.1 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif DUF1761 PF08570.10 ORX92696.1 - 1.6 9.0 5.9 3.3 8.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) GTP_EFTU PF00009.27 ORX92697.1 - 2e-47 161.3 0.1 4.7e-47 160.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX92697.1 - 1.3e-24 86.7 0.3 6.7e-24 84.4 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 ORX92697.1 - 3.3e-14 52.9 9.6 9e-14 51.5 9.6 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 ORX92697.1 - 1.2e-08 35.0 0.4 7.6e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORX92697.1 - 5e-06 26.8 1.8 7.3e-06 26.3 0.6 2.0 2 0 0 2 2 1 1 Elongation factor Tu domain 2 Arf PF00025.21 ORX92697.1 - 0.0029 17.1 0.6 2.8 7.4 0.0 3.2 2 1 1 3 3 3 1 ADP-ribosylation factor family AAA_23 PF13476.6 ORX92697.1 - 0.014 15.9 9.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORX92697.1 - 0.014 15.6 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Type_ISP_C PF18135.1 ORX92697.1 - 0.015 14.3 3.7 0.025 13.6 3.7 1.3 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain Roc PF08477.13 ORX92697.1 - 0.03 14.6 0.1 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IMD PF08397.11 ORX92697.1 - 0.031 13.6 2.6 0.057 12.8 2.6 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_29 PF13555.6 ORX92697.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FlaG PF03646.15 ORX92697.1 - 1.7 8.8 12.5 63 3.8 0.0 3.6 3 0 0 3 3 3 0 FlaG protein Dynamin_N PF00350.23 ORX92697.1 - 7.4 6.6 9.3 4 7.5 0.0 3.7 2 2 1 3 3 3 0 Dynamin family Adaptin_N PF01602.20 ORX92698.1 - 7.5e-103 344.9 13.3 1.1e-102 344.4 13.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 ORX92698.1 - 4.9e-59 198.2 0.2 1.6e-58 196.6 0.2 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 ORX92698.1 - 1.1e-58 196.7 0.0 2.9e-58 195.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 ORX92698.1 - 1.8e-10 41.0 1.0 0.0021 18.4 0.0 4.6 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 ORX92698.1 - 1.3e-06 28.1 0.8 0.0052 16.9 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 ORX92698.1 - 9.5e-06 25.7 9.8 0.00015 21.8 0.2 3.1 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 ORX92698.1 - 7.2e-05 22.9 0.0 0.00028 21.0 0.0 2.1 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform PatG_C PF18065.1 ORX92698.1 - 0.0011 18.9 0.8 0.055 13.4 0.2 3.0 3 0 0 3 3 3 1 PatG C-terminal HEAT_EZ PF13513.6 ORX92698.1 - 0.077 13.5 0.0 3.8 8.1 0.0 3.3 3 1 0 3 3 3 0 HEAT-like repeat HSP70 PF00012.20 ORX92699.1 - 9.4e-259 859.6 12.0 1.1e-258 859.4 12.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX92699.1 - 2.9e-19 69.1 0.7 2e-17 63.0 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 ORX92699.1 - 0.0076 15.6 3.8 0.016 14.5 0.3 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Spore_GerAC PF05504.11 ORX92699.1 - 0.017 15.4 18.2 0.024 14.8 0.0 3.5 3 1 0 3 3 3 0 Spore germination B3/ GerAC like, C-terminal FtsA PF14450.6 ORX92699.1 - 0.036 14.5 5.5 5.3 7.5 0.0 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Radial_spoke_3 PF06098.11 ORX92699.1 - 0.14 11.4 10.8 0.041 13.2 7.4 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 HTH_Tnp_1 PF01527.20 ORX92699.1 - 0.19 12.1 1.2 0.55 10.6 1.2 1.8 1 0 0 1 1 1 0 Transposase GATA PF00320.27 ORX92715.1 - 1.4e-28 98.2 16.1 5.2e-15 54.8 4.4 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORX92715.1 - 5.8e-11 42.0 1.6 1.7e-10 40.5 1.6 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 ORX92715.1 - 0.00043 20.3 0.8 0.22 11.7 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORX92715.1 - 0.0027 17.2 6.2 0.027 14.0 0.3 2.7 2 1 0 2 2 2 1 TFIIB zinc-binding Vps36-NZF-N PF16988.5 ORX92715.1 - 0.019 14.4 8.6 1.1 8.7 1.1 4.1 1 1 3 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OTT_1508_deam PF14441.6 ORX92715.1 - 0.028 14.4 0.5 12 6.0 0.1 2.8 2 0 0 2 2 2 0 OTT_1508-like deaminase Zn_Tnp_IS1595 PF12760.7 ORX92715.1 - 0.031 14.2 3.6 3.6 7.6 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.17 ORX92715.1 - 0.24 11.3 5.5 3.3 7.6 0.7 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2318 PF10080.9 ORX92715.1 - 0.56 10.4 3.4 44 4.3 1.0 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) DZR PF12773.7 ORX92715.1 - 0.74 9.9 10.8 2.7 8.1 7.8 3.2 2 1 2 4 4 4 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORX92715.1 - 1.1 9.2 7.0 1.3 9.0 1.4 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_15 PF17032.5 ORX92715.1 - 1.4 9.7 6.8 11 6.8 6.9 2.5 1 1 2 3 3 3 0 zinc-ribbon family ZF-HD_dimer PF04770.12 ORX92715.1 - 2.5 8.5 7.8 7.8 6.9 0.1 3.3 2 1 1 3 3 3 0 ZF-HD protein dimerisation region Auto_anti-p27 PF06677.12 ORX92715.1 - 2.9 8.1 6.0 1.7 8.8 0.6 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-B_box PF00643.24 ORX92715.1 - 3 8.1 9.0 31 4.8 0.0 3.9 4 0 0 4 4 4 0 B-box zinc finger A2L_zn_ribbon PF08792.10 ORX92715.1 - 6.3 6.6 7.5 11 5.8 0.0 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain PAPS_reduct PF01507.19 ORX92716.1 - 1.3e-28 100.3 0.0 3.6e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pyridoxal_deC PF00282.19 ORX92717.1 - 1.6e-87 293.7 0.0 2e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ORX92717.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORX92717.1 - 8.7e-05 21.6 0.0 0.00084 18.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V SepSecS PF05889.13 ORX92717.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Acyl-CoA_dh_1 PF00441.24 ORX92719.1 - 4.3e-43 147.1 0.7 6.4e-43 146.5 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORX92719.1 - 1.5e-25 90.1 0.1 5.5e-25 88.2 0.0 2.0 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORX92719.1 - 4.2e-22 78.2 0.0 7.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORX92719.1 - 1.1e-17 64.6 0.0 2.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 ORX92719.1 - 0.13 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein Ecl1 PF12855.7 ORX92720.1 - 8.2e-09 36.9 4.7 9.1e-09 36.7 4.7 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins MRP-L27 PF09809.9 ORX92721.1 - 3.3e-23 81.7 0.1 3.5e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Glyco_transf_34 PF05637.12 ORX92722.1 - 1.5e-42 145.9 0.3 1.3e-21 77.5 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORX92722.1 - 0.095 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF3020 PF11223.8 ORX92723.1 - 4.1e-18 65.6 4.7 4.1e-18 65.6 4.7 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) zf-C2H2 PF00096.26 ORX92723.1 - 8.5e-05 22.8 1.3 0.00027 21.2 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX92723.1 - 0.0003 21.4 2.0 0.00072 20.2 0.8 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX92723.1 - 0.00097 18.8 0.2 0.0018 18.0 0.2 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORX92723.1 - 0.0092 16.3 2.4 0.021 15.1 2.3 1.7 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORX92723.1 - 0.01 15.8 2.3 0.033 14.2 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX92723.1 - 0.014 15.7 0.7 0.014 15.7 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ORX92723.1 - 0.038 14.0 0.4 0.085 12.9 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_3rep PF18868.1 ORX92723.1 - 0.1 13.3 0.6 0.19 12.4 0.6 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Med13_C PF06333.12 ORX92724.1 - 6.8e-26 91.3 0.4 2.1e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 ORX92724.1 - 1.6e-22 80.5 0.0 9.6e-13 48.5 0.0 3.0 3 0 0 3 3 3 2 MID domain of medPIWI Med13_C PF06333.12 ORX92725.1 - 0.00034 20.0 0.0 0.00036 19.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain RRM_1 PF00076.22 ORX92727.1 - 3.7e-18 65.1 0.0 5.5e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FH2 PF02181.23 ORX92728.1 - 5.3e-97 325.3 25.7 2.5e-96 323.0 8.8 2.9 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.13 ORX92728.1 - 4.4e-49 166.6 1.4 4.4e-49 166.6 1.4 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORX92728.1 - 7.9e-39 133.3 1.4 7.9e-39 133.3 1.4 4.0 5 0 0 5 5 5 1 Diaphanous FH3 Domain ArnB_C PF18677.1 ORX92728.1 - 0.0081 16.2 2.8 1.9 8.7 0.1 3.7 3 0 0 3 3 3 1 Archaellum regulatory network B, C-terminal domain Drf_DAD PF06345.11 ORX92728.1 - 0.0098 15.9 0.0 0.041 13.9 0.0 2.2 1 0 0 1 1 1 1 DRF Autoregulatory Domain ANAPC4 PF12896.7 ORX92728.1 - 0.015 14.8 3.6 0.17 11.4 0.3 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 AKNA PF12443.8 ORX92728.1 - 0.87 10.3 7.1 1.4 9.6 0.1 3.7 3 0 0 3 3 3 0 AT-hook-containing transcription factor Lectin_N PF03954.14 ORX92728.1 - 2 8.2 9.4 8.3 6.2 0.2 3.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Lipoprotein_10 PF03202.13 ORX92728.1 - 2.9 8.4 4.9 23 5.4 0.4 3.7 3 0 0 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region AhpC-TSA PF00578.21 ORX92729.1 - 1.4e-30 105.8 0.0 1.8e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX92729.1 - 1.4e-10 41.1 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin GTP_EFTU PF00009.27 ORX92730.1 - 2.3e-66 223.0 0.1 3.5e-66 222.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORX92730.1 - 7.3e-33 112.9 0.0 2.2e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORX92730.1 - 8.1e-22 77.1 0.0 3e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORX92730.1 - 9.8e-14 51.2 0.0 2.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ORX92730.1 - 1.9e-12 47.4 0.0 4.9e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX92730.1 - 2.1e-06 27.8 0.2 4.1e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORX92730.1 - 0.14 11.9 0.1 0.78 9.5 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TAFII55_N PF04658.13 ORX92731.1 - 3e-48 163.6 1.5 3e-48 163.6 1.5 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region Importin_rep_6 PF18829.1 ORX92731.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.7 3 1 1 4 4 4 0 Importin repeat 6 Atg14 PF10186.9 ORX92731.1 - 6.2 5.8 13.7 11 5.0 13.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L14 PF00238.19 ORX92732.1 - 3e-49 166.2 1.5 3.3e-49 166.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Las1 PF04031.13 ORX92733.1 - 4.6e-49 166.5 0.1 8.5e-49 165.6 0.1 1.4 1 0 0 1 1 1 1 Las1-like Glucosamine_iso PF01182.20 ORX92734.1 - 6.8e-77 258.3 0.0 7.6e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GspH PF12019.8 ORX92734.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II transport protein GspH Ribosomal_L18A PF01775.17 ORX92735.1 - 5.1e-56 188.0 0.3 6.2e-56 187.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ras PF00071.22 ORX92736.1 - 3.9e-60 202.1 0.0 4.8e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX92736.1 - 1e-35 122.6 0.0 2.2e-35 121.5 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX92736.1 - 7.7e-13 48.3 0.0 9.9e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX92736.1 - 3.1e-07 30.4 0.4 0.023 14.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX92736.1 - 4.9e-06 26.6 0.0 9.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX92736.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX92736.1 - 0.00025 20.6 0.0 0.00073 19.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORX92736.1 - 0.0062 16.9 0.1 0.013 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORX92736.1 - 0.078 12.4 0.1 0.2 11.1 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORX92736.1 - 0.12 12.7 0.0 1.4 9.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ORX92736.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein EF-hand_1 PF00036.32 ORX92738.1 - 2.8e-33 111.0 13.1 4.3e-10 38.4 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX92738.1 - 7.9e-31 106.3 5.3 3.3e-15 56.3 3.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX92738.1 - 7.9e-26 87.7 9.5 7.1e-08 31.8 0.5 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORX92738.1 - 1.3e-24 85.8 6.4 9.3e-12 44.6 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORX92738.1 - 5.7e-23 79.3 11.2 3.6e-07 29.4 0.2 4.4 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 ORX92738.1 - 5.2e-08 33.2 0.3 0.0053 17.1 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORX92738.1 - 5.9e-07 29.7 0.2 0.0055 17.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORX92738.1 - 2.2e-06 27.6 2.5 0.0019 18.1 0.6 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 ORX92738.1 - 0.00095 20.0 0.1 1.6 9.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 ORX92738.1 - 0.039 14.2 1.6 3.9 7.8 0.1 2.5 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_10 PF14788.6 ORX92738.1 - 0.069 13.0 4.7 0.15 11.9 0.9 2.5 3 0 0 3 3 3 0 EF hand LXG PF04740.12 ORX92738.1 - 0.07 12.8 0.2 10 5.7 0.0 2.6 1 1 1 3 3 3 0 LXG domain of WXG superfamily SBDS PF01172.18 ORX92739.1 - 1.6e-19 69.8 0.1 1.9e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PAS_3 PF08447.12 ORX92749.1 - 1.2e-21 76.8 0.0 2.8e-13 50.0 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 ORX92749.1 - 2e-21 76.2 0.0 7.9e-14 51.8 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_11 PF14598.6 ORX92749.1 - 2.7e-11 43.6 0.0 0.00033 20.8 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORX92749.1 - 2.1e-10 40.6 0.0 0.0026 17.7 0.0 3.5 3 1 0 3 3 3 2 PAS fold GATA PF00320.27 ORX92749.1 - 6.1e-07 28.9 5.2 1.4e-06 27.8 5.2 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 ORX92749.1 - 0.0032 17.7 0.0 4.9 7.4 0.0 3.2 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ORX92749.1 - 0.063 13.3 0.0 0.99 9.5 0.0 2.5 2 0 0 2 2 2 0 PAS domain SRF-TF PF00319.18 ORX92750.1 - 2.5e-16 58.9 0.4 4.2e-16 58.1 0.4 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pol_alpha_B_N PF08418.10 ORX92750.1 - 0.007 16.4 0.2 0.0091 16.0 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Ctr PF04145.15 ORX92751.1 - 1.4e-25 90.7 8.4 5.2e-24 85.5 8.4 2.3 1 1 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.6 ORX92751.1 - 0.085 13.0 2.8 0.25 11.5 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) tRNA_bind PF01588.20 ORX92752.1 - 7.9e-30 102.8 0.0 1.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 ORX92752.1 - 0.00057 20.1 0.4 0.00057 20.1 0.4 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX92752.1 - 0.0093 16.1 0.3 0.027 14.7 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4158 PF13700.6 ORX92752.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Oxysterol_BP PF01237.18 ORX92753.1 - 3.5e-52 177.5 0.0 4.5e-50 170.5 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein DnaJ_C PF01556.18 ORX92754.1 - 6.1e-43 146.4 2.0 8.4e-43 146.0 2.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORX92754.1 - 2.6e-26 91.5 2.3 4.7e-26 90.7 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORX92754.1 - 4.6e-17 62.1 20.9 7.9e-17 61.4 20.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORX92754.1 - 0.03 14.3 9.7 0.3 11.1 0.8 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_S17 PF00366.20 ORX92754.1 - 0.051 13.7 1.4 0.1 12.8 1.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S17 HypA PF01155.19 ORX92754.1 - 0.14 12.2 12.2 1.3 9.1 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Vps39_2 PF10367.9 ORX92754.1 - 4.9 7.6 8.1 12 6.4 2.3 2.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Endonuclease_5 PF04493.14 ORX92755.1 - 1.2e-52 178.5 0.0 1.4e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V Rhodanese PF00581.20 ORX92756.1 - 9.9e-10 38.9 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DAHP_synth_2 PF01474.16 ORX92757.1 - 3.7e-206 684.8 0.0 4.2e-206 684.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family VWA_2 PF13519.6 ORX92758.1 - 1.4e-07 32.1 0.0 4.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Lectin_leg-like PF03388.13 ORX92759.1 - 6.2e-65 218.8 0.0 7e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORX92759.1 - 5.3e-05 23.3 0.1 7e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 ORX92759.1 - 0.00014 21.5 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain ANAPC10 PF03256.16 ORX92760.1 - 4.5e-56 189.4 0.1 4.9e-56 189.3 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 ORX92760.1 - 5.7e-06 26.5 0.1 1e-05 25.7 0.1 1.4 1 1 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 ORX92760.1 - 0.094 12.9 0.1 0.22 11.8 0.1 1.5 1 1 0 1 1 1 0 PITH domain XRCC1_N PF01834.16 ORX92760.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 XRCC1 N terminal domain Cation_efflux PF01545.21 ORX92761.1 - 1.2e-55 188.3 5.6 1.8e-55 187.8 5.6 1.2 1 0 0 1 1 1 1 Cation efflux family GATA PF00320.27 ORX92762.1 - 9e-16 57.2 1.8 1.5e-15 56.5 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 ORX92762.1 - 0.0039 17.3 1.2 0.0058 16.7 0.3 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Mito_carr PF00153.27 ORX92763.1 - 1e-48 163.2 0.0 1.2e-17 63.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX92763.1 - 0.034 13.3 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Gammaproteobacterial serine protease zf-LITAF-like PF10601.9 ORX92765.1 - 2.1e-15 56.7 9.0 2.7e-15 56.4 9.0 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C2H2_jaz PF12171.8 ORX92765.1 - 0.029 14.6 3.0 0.042 14.1 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 ORX92765.1 - 0.35 11.1 5.7 3.3 8.0 1.4 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain BTB PF00651.31 ORX92766.1 - 0.045 14.0 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain 14-3-3 PF00244.20 ORX92768.1 - 2.7e-105 350.8 7.1 3.1e-105 350.6 7.1 1.0 1 0 0 1 1 1 1 14-3-3 protein HMMR_C PF15908.5 ORX92768.1 - 0.061 13.6 0.8 0.11 12.8 0.8 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Sec7 PF01369.20 ORX92769.1 - 4e-36 124.4 0.1 6.6e-36 123.7 0.1 1.5 1 1 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORX92769.1 - 4.8e-16 59.2 0.3 2.2e-15 57.0 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 ORX92769.1 - 2.6e-12 47.2 0.2 1.2e-11 45.1 0.2 2.2 1 1 0 1 1 1 1 PH domain IalB PF06776.12 ORX92769.1 - 0.13 12.3 0.5 0.3 11.1 0.5 1.5 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein DnaJ-X PF14308.6 ORX92770.1 - 2.1e-55 187.4 0.3 2.1e-55 187.4 0.3 2.1 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORX92770.1 - 1.4e-25 89.2 0.8 4.8e-25 87.5 0.8 2.0 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L22 PF00237.19 ORX92770.1 - 0.018 15.3 0.4 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e zinc_ribbon_12 PF11331.8 ORX92770.1 - 0.021 14.7 1.3 0.042 13.6 1.3 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain YABBY PF04690.13 ORX92770.1 - 0.05 14.2 1.5 0.28 11.7 0.0 2.3 2 0 0 2 2 2 0 YABBY protein RNA_pol_Rpc4 PF05132.14 ORX92770.1 - 0.1 13.0 3.5 0.25 11.8 3.5 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3391 PF11871.8 ORX92770.1 - 4.2 7.9 8.5 1.2 9.7 3.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Ribosomal_S24e PF01282.19 ORX92771.1 - 1.1e-38 131.0 1.3 1.3e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e Surp PF01805.20 ORX92772.1 - 1.5e-17 63.4 0.1 4.8e-17 61.7 0.1 2.0 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 ORX92772.1 - 7.5e-15 54.5 0.0 2e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 ORX92772.1 - 0.045 14.6 0.1 0.18 12.6 0.1 2.2 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 ORX92772.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Sec8_exocyst PF04048.14 ORX92773.1 - 0.00012 22.0 3.9 0.00012 22.0 3.9 2.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 ORX92773.1 - 0.00099 19.3 2.7 0.00099 19.3 2.7 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 ORX92773.1 - 0.15 12.1 1.9 1.8 8.7 1.9 2.7 1 1 0 1 1 1 0 Vps51/Vps67 COG2 PF06148.11 ORX92773.1 - 0.48 10.5 6.3 0.26 11.4 3.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MARVEL PF01284.23 ORX92774.1 - 0.0045 17.0 2.2 0.0045 17.0 2.2 2.2 2 1 0 2 2 2 1 Membrane-associating domain Mito_morph_reg PF14972.6 ORX92774.1 - 0.014 15.0 0.7 0.02 14.5 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Sarcolipin PF05366.11 ORX92774.1 - 4.1 7.2 6.5 14 5.5 0.8 2.6 2 0 0 2 2 2 0 Sarcolipin CLP1_P PF16575.5 ORX92775.1 - 5.8e-42 143.6 0.0 1e-41 142.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 ORX92775.1 - 0.00027 21.5 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX92775.1 - 0.0071 16.6 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORX92775.1 - 0.012 16.0 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ParA PF10609.9 ORX92775.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_14 PF13173.6 ORX92775.1 - 0.044 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX92775.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family 4HBT PF03061.22 ORX92776.1 - 4.4e-12 46.2 0.0 6.1e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily SNF2_N PF00176.23 ORX92777.1 - 1.3e-59 201.7 0.1 3e-59 200.5 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX92777.1 - 2e-17 63.5 0.0 5.9e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 ORX92777.1 - 2.8e-12 46.3 2.7 1e-11 44.6 1.8 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 ORX92777.1 - 4e-09 36.7 0.0 1.6e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 ORX92777.1 - 0.00027 21.1 0.5 0.00027 21.1 0.5 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain DEAD PF00270.29 ORX92777.1 - 0.0011 18.8 0.0 0.0032 17.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.6 ORX92777.1 - 0.031 14.5 0.4 0.12 12.6 0.4 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain CHDCT2 PF08074.11 ORX92777.1 - 0.042 14.0 0.2 1.6 8.9 0.1 3.5 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Peptidase_M15 PF01427.17 ORX92777.1 - 0.21 11.3 1.5 0.61 9.8 0.2 2.3 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase Med18 PF09637.10 ORX92779.1 - 7.2e-14 52.2 0.2 7.9e-14 52.1 0.2 1.0 1 0 0 1 1 1 1 Med18 protein Med18 PF09637.10 ORX92780.1 - 0.00028 20.8 0.0 0.0027 17.6 0.0 1.9 1 1 1 2 2 2 2 Med18 protein Tam41_Mmp37 PF09139.11 ORX92781.1 - 3.3e-120 401.4 0.3 3.7e-120 401.2 0.3 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Ribosomal_L44 PF00935.19 ORX92782.1 - 3.9e-37 126.6 11.0 5.7e-37 126.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Myb_DNA-bind_4 PF13837.6 ORX92783.1 - 5.8e-16 58.7 2.8 5.8e-16 58.7 2.8 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX92783.1 - 0.0007 19.7 1.1 0.0014 18.7 1.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX92783.1 - 0.0012 19.2 1.8 0.0012 19.2 1.8 2.6 3 1 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 ORX92783.1 - 0.0023 18.2 0.8 0.0067 16.7 0.8 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORX92783.1 - 0.016 15.2 6.6 0.018 15.1 2.8 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NPF PF16601.5 ORX92783.1 - 8.3 6.8 11.9 7.7 6.9 7.3 2.4 2 0 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif Ribosomal_L7Ae PF01248.26 ORX92784.1 - 3e-27 94.2 0.0 3.6e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ORX92784.1 - 0.00078 19.3 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 ORX92784.1 - 0.0084 16.2 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 MatP_C PF17414.2 ORX92784.1 - 0.073 13.3 1.2 0.28 11.4 0.2 2.3 2 1 1 3 3 3 0 MatP C-terminal ribbon-helix-helix domain zinc_ribbon_10 PF10058.9 ORX92801.1 - 0.0033 17.1 4.8 0.0062 16.2 4.8 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_SprT PF17283.2 ORX92801.1 - 0.067 13.1 3.2 0.44 10.5 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain F420_oxidored PF03807.17 ORX92802.1 - 3e-14 53.4 0.3 4.7e-13 49.5 0.0 2.7 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORX92802.1 - 6.2e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORX92802.1 - 9.7e-07 28.5 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 ORX92802.1 - 3.6e-05 23.2 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ORX92802.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORX92802.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 ORX92802.1 - 0.047 13.6 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX92802.1 - 0.047 13.7 0.1 0.36 10.8 0.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORX92802.1 - 0.058 13.0 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORX92802.1 - 0.074 13.5 0.0 0.24 11.8 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Ferric_reduct PF01794.19 ORX92802.1 - 0.55 10.4 10.8 3 8.0 3.6 2.6 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF2953 PF11167.8 ORX92802.1 - 1.7 8.8 5.9 39 4.4 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) F420_oxidored PF03807.17 ORX92803.1 - 1.3e-12 48.1 0.0 2.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX92803.1 - 5.5e-06 25.9 0.0 8.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ferric_reduct PF01794.19 ORX92803.1 - 1.7e-05 24.9 6.6 1.7e-05 24.9 6.6 2.4 2 1 2 4 4 4 1 Ferric reductase like transmembrane component NAD_Gly3P_dh_N PF01210.23 ORX92803.1 - 5.8e-05 23.1 0.1 0.0039 17.2 0.1 2.5 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 ORX92803.1 - 0.00058 19.9 0.0 0.0036 17.4 0.0 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 ORX92803.1 - 0.00072 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 ORX92803.1 - 0.00096 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORX92803.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORX92803.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Pyr_redox_2 PF07992.14 ORX92803.1 - 0.029 13.6 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 ORX92803.1 - 0.03 14.8 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 ORX92803.1 - 0.062 13.8 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain ApbA PF02558.16 ORX92803.1 - 0.074 12.7 1.1 0.32 10.7 0.1 2.4 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF4954 PF16314.5 ORX92803.1 - 0.19 9.8 0.0 0.3 9.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Ras PF00071.22 ORX92804.1 - 5e-60 201.8 0.2 5.9e-60 201.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX92804.1 - 7.2e-20 71.4 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX92804.1 - 2.3e-09 36.9 0.0 2.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX92804.1 - 2.1e-05 24.5 0.9 0.017 15.0 0.0 2.5 1 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORX92804.1 - 0.00012 21.6 0.0 0.00038 20.1 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ORX92804.1 - 0.00072 19.6 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 ORX92804.1 - 0.0017 17.9 0.1 0.004 16.7 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORX92804.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 ORX92804.1 - 0.078 13.0 0.8 1.2 9.2 0.8 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ORX92804.1 - 0.43 10.3 2.4 2.8 7.7 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.25 ORX92805.1 - 3.7e-28 98.3 0.0 2.7e-25 89.0 0.0 3.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX92805.1 - 4.9e-14 52.5 0.0 2.6e-11 43.5 0.0 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX92805.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_deac_1 PF01522.21 ORX92806.1 - 8e-32 109.7 0.1 1.9e-31 108.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORX92806.1 - 0.13 11.9 1.1 0.24 11.0 0.4 1.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) adh_short PF00106.25 ORX92807.1 - 1.4e-20 73.5 0.0 1.6e-18 66.9 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX92807.1 - 7.8e-14 51.8 0.0 1.5e-12 47.6 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORX92807.1 - 3.2e-06 26.8 0.0 4.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORX92807.1 - 8.1e-06 25.9 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORX92807.1 - 5e-05 22.8 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORX92807.1 - 0.00014 21.8 0.0 0.0023 17.8 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox_3 PF13738.6 ORX92807.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_4 PF07993.12 ORX92807.1 - 0.025 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Ion_trans_2 PF07885.16 ORX92808.1 - 5.7e-11 42.2 5.1 1.4e-10 41.0 5.1 1.6 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 ORX92808.1 - 1.4e-09 38.0 0.0 4.7e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 ORX92808.1 - 0.002 17.4 2.1 0.0038 16.5 2.1 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 ORX92808.1 - 0.12 12.7 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain PAP_assoc PF03828.19 ORX92810.1 - 6.8e-17 61.4 0.1 1.2e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORX92810.1 - 4.6e-14 52.5 0.0 8.8e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORX92810.1 - 0.0002 21.3 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 ORX92810.1 - 0.032 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Pmp3 PF01679.17 ORX92812.1 - 2.3e-17 62.9 4.3 3e-17 62.5 4.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arrestin_C PF02752.22 ORX92814.1 - 1.2e-10 42.0 0.0 2.6e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX92814.1 - 1.7e-07 31.4 0.0 5.3e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX92814.1 - 0.013 15.3 0.0 0.082 12.6 0.0 2.3 2 1 1 3 3 3 0 Arrestin_N terminal like Uricase PF01014.18 ORX92819.1 - 0.0027 18.0 0.1 0.043 14.1 0.0 2.3 2 1 0 2 2 2 1 Uricase RUN PF02759.19 ORX92819.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 RUN domain Acetyltransf_1 PF00583.25 ORX92820.1 - 1.3e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX92820.1 - 2.2e-09 37.6 0.0 3.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX92820.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX92820.1 - 4.7e-05 23.5 0.0 8.3e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CsbD PF05532.12 ORX92834.1 - 5.5e-09 35.8 4.2 1.9e-05 24.5 0.9 2.1 2 0 0 2 2 2 2 CsbD-like Sod_Cu PF00080.20 ORX92835.1 - 1.5e-16 60.9 1.1 3.5e-16 59.6 0.3 1.9 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 ORX92836.1 - 8.3e-15 55.2 0.9 1.2e-14 54.7 0.9 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 ORX92837.1 - 2.6e-70 236.8 0.0 3.1e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92837.1 - 5.6e-35 120.9 0.0 7.5e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX92837.1 - 0.00067 18.7 0.0 0.00091 18.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX92837.1 - 0.0082 15.5 0.0 0.015 14.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX92837.1 - 0.032 14.1 0.0 0.098 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SGT1 PF07093.11 ORX92838.1 - 1.3e-153 512.6 0.4 1.6e-153 512.3 0.4 1.0 1 0 0 1 1 1 1 SGT1 protein AA_permease PF00324.21 ORX92839.1 - 1e-132 443.2 39.2 1.1e-132 443.0 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX92839.1 - 2e-42 145.5 44.1 2.5e-42 145.2 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORX92840.1 - 7.6e-130 433.7 40.4 9.4e-130 433.4 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX92840.1 - 8.2e-40 136.9 45.9 2.6e-39 135.3 45.2 1.8 1 1 1 2 2 2 2 Amino acid permease G-patch PF01585.23 ORX92842.1 - 3.3e-11 42.9 0.4 9.8e-11 41.4 0.4 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORX92842.1 - 0.00026 21.0 1.2 0.00026 21.0 1.2 3.8 2 1 0 2 2 2 1 G-patch domain CDC45 PF02724.14 ORX92842.1 - 0.32 9.2 23.9 0.37 9.0 23.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 ORX92842.1 - 3.5 6.9 15.0 6.9 6.0 15.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) COX7a PF02238.15 ORX92843.1 - 2.9e-19 69.2 0.1 3.2e-19 69.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII GPCR_chapero_1 PF11904.8 ORX92844.1 - 8.9e-09 35.2 0.0 4.9e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 ORX92844.1 - 0.00046 20.7 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX92844.1 - 0.0032 17.8 0.0 0.59 10.9 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ORX92844.1 - 0.0088 16.6 0.1 0.11 13.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX92844.1 - 0.057 13.8 0.1 0.23 11.8 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPX2 PF06886.11 ORX92845.1 - 6.6e-06 26.3 6.5 6.6e-06 26.3 6.5 4.4 4 0 0 4 4 4 3 Targeting protein for Xklp2 (TPX2) TRAP_alpha PF03896.16 ORX92846.1 - 1.3e-20 73.8 0.6 1.6e-20 73.5 0.6 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1368 PF07112.11 ORX92846.1 - 0.0065 15.3 0.1 0.0096 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1368) Spore_YhaL PF14147.6 ORX92846.1 - 0.098 12.4 0.1 16 5.3 0.0 2.6 2 0 0 2 2 2 0 Sporulation protein YhaL Aldedh PF00171.22 ORX92847.1 - 2.3e-130 435.2 0.1 2.7e-130 435.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRM_1 PF00076.22 ORX92848.1 - 1.4e-79 261.9 0.0 3.6e-20 71.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX92848.1 - 7.7e-07 29.1 0.0 0.15 12.2 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif RRM_Rrp7 PF17799.1 ORX92848.1 - 0.0004 20.2 0.0 4.4 7.1 0.0 4.0 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain DUF3932 PF13068.6 ORX92848.1 - 0.00046 20.4 0.0 6.3 7.1 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3932) Spo7_2_N PF15407.6 ORX92848.1 - 0.11 12.2 0.1 6.9 6.4 0.0 2.7 3 0 0 3 3 3 0 Sporulation protein family 7 Na_H_Exchanger PF00999.21 ORX92850.1 - 1.3e-58 198.7 27.4 1.5e-58 198.4 27.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-C2H2 PF00096.26 ORX92851.1 - 9.6e-17 60.4 19.3 1.2e-05 25.5 2.5 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX92851.1 - 6.8e-16 57.9 19.1 6.3e-08 32.7 2.0 3.5 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX92851.1 - 6.9e-14 51.4 16.2 0.00049 20.7 2.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX92851.1 - 5.5e-09 35.8 12.4 0.00034 20.5 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX92851.1 - 1.2e-06 28.6 5.9 0.041 14.2 0.0 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORX92851.1 - 7.5e-06 26.3 8.5 0.3 11.6 0.8 3.1 2 1 1 3 3 3 3 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 ORX92851.1 - 4.4e-05 23.5 3.3 0.61 10.2 0.1 3.2 2 1 1 3 3 3 2 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 ORX92851.1 - 0.0005 20.7 6.1 0.013 16.2 5.6 2.6 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORX92851.1 - 0.001 19.4 7.0 1.5 9.3 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX92851.1 - 0.0014 18.9 5.9 0.0018 18.5 2.2 2.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf_UBZ PF18439.1 ORX92851.1 - 0.0045 16.5 3.2 0.98 9.1 0.2 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 ORX92851.1 - 0.0049 16.7 1.9 0.0049 16.7 1.9 3.4 3 1 0 3 3 3 1 zinc-finger of a C2HC-type zf-BED PF02892.15 ORX92851.1 - 0.0074 16.3 8.3 0.16 12.0 1.6 2.9 1 1 2 3 3 3 2 BED zinc finger FANCL_C PF11793.8 ORX92851.1 - 0.0092 16.1 2.2 0.11 12.7 0.1 2.3 1 1 1 2 2 2 1 FANCL C-terminal domain Zn-ribbon_8 PF09723.10 ORX92851.1 - 0.011 15.8 9.5 0.94 9.7 0.6 3.0 2 1 1 3 3 3 0 Zinc ribbon domain PyrI_C PF02748.15 ORX92851.1 - 0.012 15.5 7.1 0.18 11.8 0.5 2.6 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 ORX92851.1 - 0.03 15.1 2.3 0.033 14.9 1.7 1.5 1 1 0 1 1 1 0 zinc-ribbon family zf-AN1 PF01428.16 ORX92851.1 - 0.039 14.1 16.1 2 8.6 1.9 3.3 1 1 2 3 3 3 0 AN1-like Zinc finger HypA PF01155.19 ORX92851.1 - 0.055 13.5 1.1 0.068 13.2 0.4 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 ORX92851.1 - 0.069 13.5 5.6 1.5 9.2 0.1 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Cript PF10235.9 ORX92851.1 - 0.12 13.0 2.8 0.077 13.6 1.2 1.5 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT CpXC PF14353.6 ORX92851.1 - 0.17 11.9 5.7 8.4 6.5 0.1 3.0 1 1 2 3 3 3 0 CpXC protein zf-LYAR PF08790.11 ORX92851.1 - 0.23 11.4 11.4 8.6 6.4 0.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_1 PF00130.22 ORX92851.1 - 0.32 10.9 6.5 1.8 8.5 3.5 2.5 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHCC PF10276.9 ORX92851.1 - 0.41 10.8 0.4 0.41 10.8 0.4 2.5 3 0 0 3 3 2 0 Zinc-finger domain zf-C2H2_11 PF16622.5 ORX92851.1 - 0.47 10.3 13.8 0.78 9.6 0.4 3.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 ORX92851.1 - 0.85 9.6 5.9 20 5.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain HNH PF01844.23 ORX92851.1 - 1.2 9.3 9.4 1.9 8.7 0.2 2.9 3 0 0 3 3 3 0 HNH endonuclease RNHCP PF12647.7 ORX92851.1 - 2 8.5 7.0 1.4 8.9 0.3 2.5 2 1 0 2 2 2 0 RNHCP domain Ank PF00023.30 ORX92853.1 - 1.3e-17 63.3 0.1 7.4e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ORX92853.1 - 3e-14 53.4 0.0 4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX92853.1 - 1.1e-13 51.1 0.2 8.5e-09 35.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX92853.1 - 7.9e-13 48.6 0.1 1.3e-07 32.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX92853.1 - 5.4e-12 44.8 0.0 8.8e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat TFIIS_C PF01096.18 ORX92854.1 - 6e-11 42.0 0.1 1.2e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 ORX92854.1 - 6.8e-05 22.5 0.4 0.00013 21.6 0.4 1.4 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain DUF3268 PF11672.8 ORX92854.1 - 0.0036 17.6 0.2 0.0074 16.6 0.2 1.5 2 0 0 2 2 2 1 zinc-finger-containing domain DZR PF12773.7 ORX92854.1 - 0.033 14.2 0.3 0.053 13.6 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Rpr2 PF04032.16 ORX92854.1 - 0.033 14.5 0.2 0.041 14.2 0.2 1.3 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 ORX92854.1 - 0.25 11.5 2.0 14 5.9 2.5 2.2 1 1 1 2 2 2 0 Zinc ribbon domain HNH PF01844.23 ORX92854.1 - 0.42 10.8 5.3 5.8 7.2 3.9 2.4 1 1 1 2 2 2 0 HNH endonuclease zf-C2H2_6 PF13912.6 ORX92854.1 - 0.77 9.8 3.5 3.5 7.7 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.6 ORX92854.1 - 2.3 8.1 5.7 1.9 8.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HeH PF12949.7 ORX92855.1 - 6.4e-10 38.6 0.1 9.3e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 HeH/LEM domain Armet PF10208.9 ORX92855.1 - 0.00046 20.1 0.2 0.0005 20.0 0.2 1.1 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding PEN-2 PF10251.9 ORX92856.1 - 1.6e-28 99.0 2.0 1.8e-28 98.8 2.0 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase MHYT PF03707.16 ORX92856.1 - 0.033 14.3 0.1 0.047 13.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Chitin_synth_1 PF01644.17 ORX92857.1 - 1.1e-70 236.9 0.1 1.6e-70 236.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORX92857.1 - 3.4e-30 103.8 0.1 7.1e-30 102.8 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORX92857.1 - 9.7e-29 100.4 3.7 3.7e-23 82.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX92857.1 - 1.8e-07 31.3 0.2 1.8e-07 31.3 0.2 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX92857.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Vps5 PF09325.10 ORX92861.1 - 1.9e-64 217.5 10.6 2.8e-64 216.9 10.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORX92861.1 - 6.3e-28 97.0 0.1 2.5e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 ORX92861.1 - 0.032 13.7 5.3 0.76 9.2 5.3 2.3 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Syntaxin_2 PF14523.6 ORX92861.1 - 0.53 10.7 11.6 5.6 7.4 4.6 3.2 2 1 1 3 3 3 0 Syntaxin-like protein TnpV PF14198.6 ORX92861.1 - 0.62 10.1 3.2 0.81 9.7 0.9 2.3 1 1 0 1 1 1 0 Transposon-encoded protein TnpV AAA PF00004.29 ORX92862.1 - 2.3e-42 144.6 0.0 4.2e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORX92862.1 - 8.2e-08 32.1 0.0 2.5e-07 30.6 0.0 1.8 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 ORX92862.1 - 1e-07 31.7 0.0 3.5e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORX92862.1 - 2.7e-07 30.7 0.9 2.1e-06 27.8 0.9 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORX92862.1 - 3.7e-07 30.0 0.0 9.3e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX92862.1 - 2.2e-06 28.0 1.3 0.0024 18.2 0.0 2.9 1 1 2 3 3 3 2 AAA domain AAA_2 PF07724.14 ORX92862.1 - 5.2e-06 26.7 0.0 9.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORX92862.1 - 6.3e-05 22.3 0.2 0.0005 19.4 0.0 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 ORX92862.1 - 0.00035 21.0 1.8 0.0032 17.9 1.5 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORX92862.1 - 0.00064 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 ORX92862.1 - 0.00067 19.3 2.5 0.071 12.7 0.2 2.8 1 1 2 3 3 3 1 AAA domain Mg_chelatase PF01078.21 ORX92862.1 - 0.00077 18.9 0.2 0.0019 17.6 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORX92862.1 - 0.00087 19.8 0.0 0.0028 18.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ORX92862.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 ORX92862.1 - 0.0012 18.2 0.1 1.6 8.1 0.1 2.5 1 1 1 2 2 2 2 Bacterial TniB protein AAA_19 PF13245.6 ORX92862.1 - 0.0022 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 ORX92862.1 - 0.0031 17.4 0.1 0.0078 16.1 0.1 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_14 PF13173.6 ORX92862.1 - 0.0047 17.0 0.0 0.0097 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORX92862.1 - 0.0055 16.9 0.1 0.012 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORX92862.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 ORX92862.1 - 0.015 14.6 0.5 2 7.7 0.1 2.2 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 ORX92862.1 - 0.017 15.1 0.4 0.33 10.8 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 ORX92862.1 - 0.035 13.6 0.1 0.1 12.1 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORX92862.1 - 0.041 14.1 0.1 0.099 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX92862.1 - 0.062 13.0 0.3 0.16 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain SCAN PF02023.17 ORX92862.1 - 0.071 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 SCAN domain RNA_helicase PF00910.22 ORX92862.1 - 0.077 13.4 0.0 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase FCH PF00611.23 ORX92862.1 - 0.097 13.0 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Sigma54_activat PF00158.26 ORX92862.1 - 0.1 12.3 0.1 0.64 9.7 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain Guanylate_kin PF00625.21 ORX92862.1 - 0.11 12.1 0.1 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 Guanylate kinase TsaE PF02367.17 ORX92862.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 ORX92862.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 ORX92862.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF508 PF04370.12 ORX92863.1 - 1.6 8.5 6.7 5.1 6.8 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF508) NMT_C PF02799.15 ORX92864.1 - 0.13 11.7 0.4 9.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Coatomer_WDAD PF04053.14 ORX92865.1 - 1.5e-137 459.3 0.5 2.9e-137 458.4 0.5 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 ORX92865.1 - 1.5e-135 452.1 0.0 2e-135 451.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 ORX92865.1 - 9.8e-47 156.0 12.4 2.6e-08 34.4 0.4 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92865.1 - 2.8e-13 50.0 0.3 0.00016 21.9 0.1 6.2 6 1 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Baculo_IE-1 PF05290.11 ORX92865.1 - 0.046 13.7 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 ORX92865.1 - 0.077 12.8 1.8 0.2 11.5 1.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nup160 PF11715.8 ORX92865.1 - 0.089 11.4 5.3 1.2 7.7 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 SRA1 PF07304.11 ORX92866.1 - 2.9e-14 53.1 0.3 3.5e-14 52.8 0.3 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 ORX92866.1 - 3.2e-08 33.7 1.9 1.7e-06 28.2 1.3 2.2 1 1 1 2 2 2 2 Prp18 domain MutS_V PF00488.21 ORX92867.1 - 2.2e-54 184.4 1.0 4.8e-54 183.3 1.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORX92867.1 - 8.2e-22 78.4 0.0 2.1e-19 70.5 0.0 2.5 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 ORX92867.1 - 5.6e-12 45.8 0.1 1.1e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 ORX92867.1 - 2.3e-07 31.2 0.2 4.8e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 ORX92867.1 - 0.0097 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 ORX92867.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX92867.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sec1 PF00995.23 ORX92868.1 - 2.9e-112 376.8 4.6 3.3e-112 376.6 4.6 1.0 1 0 0 1 1 1 1 Sec1 family DAO PF01266.24 ORX92870.1 - 9.6e-48 163.5 0.1 1.3e-47 163.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ORX92870.1 - 7.6e-46 155.1 0.2 1.4e-45 154.2 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ORX92870.1 - 2.3e-08 33.5 3.2 0.00028 20.1 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ORX92870.1 - 3.3e-05 23.4 1.0 0.00018 21.0 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX92870.1 - 0.00024 20.4 0.9 0.001 18.3 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORX92870.1 - 0.00052 19.4 0.0 0.033 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ORX92870.1 - 0.0012 18.0 0.4 0.21 10.6 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORX92870.1 - 0.0018 18.5 0.2 0.0089 16.2 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ORX92870.1 - 0.0095 15.8 0.1 0.024 14.5 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ORX92870.1 - 0.026 13.8 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4148 PF13663.6 ORX92870.1 - 0.034 14.3 0.4 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Thi4 PF01946.17 ORX92870.1 - 0.039 13.2 0.6 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ORX92870.1 - 0.11 13.1 0.2 0.32 11.6 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX92870.1 - 0.13 11.0 0.4 0.23 10.1 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Trypsin PF00089.26 ORX92871.1 - 2.1e-29 102.9 0.0 2.4e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX92871.1 - 2.6e-06 28.4 0.0 3.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain BCDHK_Adom3 PF10436.9 ORX92872.1 - 3.1e-23 82.4 0.2 4.6e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX92872.1 - 9.2e-10 39.0 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORX92872.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-synt_ab PF00006.25 ORX92873.1 - 1.6e-68 230.5 0.0 2.5e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX92873.1 - 6.6e-12 45.8 0.6 1.3e-11 44.8 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 ORX92873.1 - 0.093 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF4448 PF14610.6 ORX92874.1 - 6.9e-07 29.2 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mid2 PF04478.12 ORX92874.1 - 0.02 14.7 1.3 0.027 14.3 0.4 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor FTR1 PF03239.14 ORX92874.1 - 0.16 11.1 0.5 0.25 10.5 0.5 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family PP2C PF00481.21 ORX92875.1 - 3.9e-80 269.2 0.0 5.1e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C NTP_transf_9 PF04248.12 ORX92876.1 - 3.5e-11 42.8 40.2 0.48 10.3 0.1 11.3 4 4 8 12 12 12 7 Domain of unknown function (DUF427) Preseq_ALAS PF09029.10 ORX92876.1 - 0.0012 19.3 26.9 1.1 9.7 1.8 6.9 3 3 1 4 4 4 4 5-aminolevulinate synthase presequence CLIP PF12032.8 ORX92876.1 - 0.016 15.5 32.9 29 5.0 0.3 10.4 4 4 8 12 12 12 0 Regulatory CLIP domain of proteinases BING4CT PF08149.11 ORX92876.1 - 0.1 12.4 3.3 61 3.5 0.0 5.0 5 3 1 6 6 6 0 BING4CT (NUC141) domain Nitroreductase PF00881.24 ORX92878.1 - 5e-32 111.3 0.0 6.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ORX92878.1 - 4.1e-06 26.5 0.0 0.0016 18.0 0.1 2.8 2 1 1 3 3 3 3 Putative TM nitroreductase Diphthamide_syn PF01866.17 ORX92879.1 - 2.4e-90 303.1 2.0 2.7e-89 299.6 2.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein B12-binding PF02310.19 ORX92879.1 - 0.14 12.2 0.0 22 5.1 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain CCDC144C PF14915.6 ORX92880.1 - 0.00014 21.1 8.1 0.00017 20.8 8.1 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Spc7 PF08317.11 ORX92880.1 - 0.00059 18.8 10.4 0.00068 18.6 10.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF713 PF05218.14 ORX92880.1 - 0.0017 18.1 3.6 0.0022 17.7 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF713) HAUS-augmin3 PF14932.6 ORX92880.1 - 0.0017 18.0 7.9 0.0021 17.7 7.9 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 FapA PF03961.13 ORX92880.1 - 0.0026 16.4 5.9 0.0031 16.2 5.9 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A MAD PF05557.13 ORX92880.1 - 0.0033 15.9 9.8 0.0036 15.7 9.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Vps5 PF09325.10 ORX92880.1 - 0.0036 16.9 8.3 0.005 16.4 0.5 2.0 1 1 1 2 2 2 1 Vps5 C terminal like FPP PF05911.11 ORX92880.1 - 0.0042 15.4 11.8 0.0047 15.2 11.8 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF812 PF05667.11 ORX92880.1 - 0.0053 15.7 8.6 0.007 15.3 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 ORX92880.1 - 0.0077 16.3 14.7 0.0092 16.0 6.4 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 ORX92880.1 - 0.0085 16.3 10.6 0.031 14.5 10.6 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 ORX92880.1 - 0.0087 16.3 5.4 5.5 7.4 0.1 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TACC_C PF05010.14 ORX92880.1 - 0.0094 15.8 8.4 0.044 13.6 4.7 2.1 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CREPT PF16566.5 ORX92880.1 - 0.011 15.9 4.6 0.015 15.4 4.6 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour KELK PF15796.5 ORX92880.1 - 0.012 16.1 8.5 0.018 15.5 8.5 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.6 ORX92880.1 - 0.016 14.6 10.1 0.032 13.6 10.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF773 PF05600.12 ORX92880.1 - 0.017 13.9 5.7 0.02 13.7 5.7 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Syntaxin_2 PF14523.6 ORX92880.1 - 0.017 15.4 1.4 0.017 15.4 1.4 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DUF4407 PF14362.6 ORX92880.1 - 0.019 14.4 2.5 0.022 14.1 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FemAB PF02388.16 ORX92880.1 - 0.022 13.7 3.0 0.026 13.4 3.0 1.0 1 0 0 1 1 1 0 FemAB family DUF3584 PF12128.8 ORX92880.1 - 0.029 11.9 6.9 0.031 11.8 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.13 ORX92880.1 - 0.037 14.4 13.8 0.28 11.5 5.4 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RPW8 PF05659.11 ORX92880.1 - 0.044 13.5 1.8 0.089 12.5 1.8 1.6 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prefoldin_2 PF01920.20 ORX92880.1 - 0.046 13.7 10.7 0.29 11.1 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit Y_phosphatase PF00102.27 ORX92880.1 - 0.047 13.3 0.1 0.051 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CEP63 PF17045.5 ORX92880.1 - 0.056 13.4 10.4 0.06 13.3 10.4 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Peptidase_U57 PF05582.12 ORX92880.1 - 0.056 12.7 1.9 0.062 12.6 1.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 BPS1 PF05633.11 ORX92880.1 - 0.061 12.3 3.4 0.078 12.0 2.7 1.3 1 1 0 1 1 1 0 Protein BYPASS1-related Apolipoprotein PF01442.18 ORX92880.1 - 0.061 13.2 7.5 0.1 12.4 7.5 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.19 ORX92880.1 - 0.063 11.2 5.3 0.072 11.0 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 ORX92880.1 - 0.072 13.3 4.7 0.22 11.7 4.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 ORX92880.1 - 0.079 13.0 1.5 0.1 12.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 ORX92880.1 - 0.084 11.7 4.9 0.093 11.6 4.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PDE4_UCR PF18100.1 ORX92880.1 - 0.085 13.5 2.3 0.079 13.6 1.3 1.5 1 1 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) KASH_CCD PF14662.6 ORX92880.1 - 0.093 12.6 11.8 0.1 12.4 11.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH XhlA PF10779.9 ORX92880.1 - 0.1 12.8 3.9 2 8.7 0.4 2.2 1 1 1 2 2 2 0 Haemolysin XhlA FUSC PF04632.12 ORX92880.1 - 0.1 11.1 1.1 0.11 11.0 1.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec34 PF04136.15 ORX92880.1 - 0.11 12.4 4.7 0.24 11.3 3.8 1.8 1 1 1 2 2 2 0 Sec34-like family Exonuc_VII_L PF02601.15 ORX92880.1 - 0.11 12.1 6.1 0.12 11.9 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DLP_helical PF18709.1 ORX92880.1 - 0.11 11.7 4.8 0.072 12.3 1.2 1.8 1 1 1 2 2 2 0 Dynamin-like helical domain Spectrin PF00435.21 ORX92880.1 - 0.13 12.8 8.6 0.79 10.2 8.0 2.0 1 1 0 1 1 1 0 Spectrin repeat DHR10 PF18595.1 ORX92880.1 - 0.13 12.3 14.0 0.35 10.9 7.3 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain BST2 PF16716.5 ORX92880.1 - 0.14 12.8 9.0 0.11 13.1 6.3 1.8 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Lebercilin PF15619.6 ORX92880.1 - 0.14 11.8 12.0 0.19 11.4 12.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FliD_C PF07195.12 ORX92880.1 - 0.14 11.5 5.0 0.085 12.3 0.8 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Taxilin PF09728.9 ORX92880.1 - 0.17 11.1 13.4 0.23 10.6 13.4 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein IFT57 PF10498.9 ORX92880.1 - 0.17 10.8 8.3 0.2 10.6 8.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 ORX92880.1 - 0.17 12.4 5.3 0.22 12.1 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 VPS38 PF17649.1 ORX92880.1 - 0.18 10.7 6.6 0.22 10.4 6.6 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF3450 PF11932.8 ORX92880.1 - 0.18 11.1 8.9 0.21 10.9 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORX92880.1 - 0.18 11.6 9.0 3.1 7.6 4.9 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF919 PF06034.11 ORX92880.1 - 0.18 11.6 9.2 0.86 9.5 3.6 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) BBS2_C PF14782.6 ORX92880.1 - 0.18 10.5 3.8 0.16 10.7 2.8 1.4 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal CCDC-167 PF15188.6 ORX92880.1 - 0.18 12.1 8.4 0.47 10.8 8.4 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 EzrA PF06160.12 ORX92880.1 - 0.19 9.8 8.9 0.27 9.3 8.9 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Val_tRNA-synt_C PF10458.9 ORX92880.1 - 0.2 12.0 9.0 7.4 6.9 7.6 3.0 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Atg14 PF10186.9 ORX92880.1 - 0.23 10.5 5.7 0.27 10.3 5.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 ORX92880.1 - 0.27 11.4 13.3 0.76 10.0 13.3 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Gp58 PF07902.11 ORX92880.1 - 0.28 9.4 2.7 0.34 9.2 2.7 1.0 1 0 0 1 1 1 0 gp58-like protein Snapin_Pallidin PF14712.6 ORX92880.1 - 0.28 11.6 5.1 0.75 10.2 1.1 2.2 1 1 0 2 2 2 0 Snapin/Pallidin Allexi_40kDa PF05549.11 ORX92880.1 - 0.28 10.6 1.8 0.31 10.5 1.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Golgin_A5 PF09787.9 ORX92880.1 - 0.29 10.5 9.8 0.47 9.9 9.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4446 PF14584.6 ORX92880.1 - 0.31 11.0 5.6 1.8 8.6 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF883 PF05957.13 ORX92880.1 - 0.35 11.5 3.1 0.55 10.9 0.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phage_GPO PF05929.11 ORX92880.1 - 0.37 10.4 4.5 0.43 10.2 4.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc24 PF08286.11 ORX92880.1 - 0.42 10.9 6.6 0.23 11.7 3.5 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HemX PF04375.14 ORX92880.1 - 0.46 9.7 6.9 0.59 9.4 6.9 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Occludin_ELL PF07303.13 ORX92880.1 - 0.46 11.2 8.4 1.5 9.6 3.6 2.2 1 1 1 2 2 2 0 Occludin homology domain FlaC_arch PF05377.11 ORX92880.1 - 0.55 10.7 3.0 15 6.1 2.4 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TarH PF02203.15 ORX92880.1 - 0.64 9.9 4.1 2.5 8.0 4.1 1.8 1 1 0 1 1 1 0 Tar ligand binding domain homologue DUF4618 PF15397.6 ORX92880.1 - 0.66 9.3 8.6 1.4 8.3 8.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 ORX92880.1 - 0.75 10.3 14.1 0.93 10.0 14.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Lectin_N PF03954.14 ORX92880.1 - 0.82 9.4 5.4 20 5.0 5.4 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 ORX92880.1 - 0.97 8.6 9.3 1.8 7.7 9.3 1.5 1 1 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 ORX92880.1 - 0.98 9.8 14.7 2.1 8.7 12.6 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 ORX92880.1 - 1.2 9.6 9.3 9.5 6.7 0.2 2.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GrpE PF01025.19 ORX92880.1 - 1.4 8.5 10.8 2.1 8.0 3.1 1.9 1 1 1 2 2 2 0 GrpE DUF4140 PF13600.6 ORX92880.1 - 2.2 8.8 6.2 36 4.9 6.2 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.6 ORX92880.1 - 2.7 8.0 9.7 4.5 7.3 6.6 2.0 1 1 1 2 2 2 0 FlxA-like protein CENP-H PF05837.12 ORX92880.1 - 4.7 7.7 8.7 7.5 7.0 8.7 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) zf-C2H2_aberr PF17017.5 ORX92881.1 - 1.2e-06 28.8 5.6 0.015 15.4 0.2 3.1 3 1 1 4 4 4 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORX92881.1 - 1.4e-05 25.2 13.4 0.0036 17.7 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORX92881.1 - 0.0006 20.4 5.5 0.29 11.8 0.0 3.3 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORX92881.1 - 0.0021 18.8 16.5 0.051 14.4 1.0 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger OrsD PF12013.8 ORX92881.1 - 0.12 12.9 2.1 6.5 7.2 0.2 3.0 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Metallophos PF00149.28 ORX92882.1 - 1e-39 137.2 0.1 1.7e-39 136.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX92882.1 - 9.1e-05 22.8 1.0 0.0002 21.7 1.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 ORX92882.1 - 0.044 14.0 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 ORX92882.1 - 0.048 13.3 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DHBP_synthase PF00926.19 ORX92883.1 - 1e-78 263.3 0.0 1.2e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF4058 PF13267.6 ORX92883.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) WBS_methylT PF12589.8 ORX92884.1 - 1.1e-21 77.3 3.3 1.8e-21 76.7 3.3 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 ORX92884.1 - 5.1e-07 30.3 0.0 8.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX92884.1 - 5.7e-07 30.2 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 ORX92884.1 - 0.00085 19.6 0.1 0.005 17.2 0.1 2.1 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 ORX92884.1 - 0.0053 16.6 0.0 0.0093 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX92884.1 - 0.0091 16.7 0.1 0.02 15.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX92884.1 - 0.022 14.6 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORX92884.1 - 0.19 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ENTH PF01417.20 ORX92886.1 - 2.9e-48 163.0 0.4 3.4e-48 162.8 0.4 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ORX92886.1 - 8.1e-07 28.3 0.2 9e-07 28.2 0.2 1.0 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 ORX92886.1 - 0.0084 16.0 0.1 0.02 14.7 0.1 1.5 1 1 0 1 1 1 1 VHS domain Pro_isomerase PF00160.21 ORX92887.1 - 7.2e-30 104.3 0.1 7.9e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ANAPC8 PF04049.13 ORX92888.1 - 1.1e-30 106.5 5.5 2.3e-28 99.0 1.7 3.8 2 2 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 ORX92888.1 - 5.1e-25 86.2 35.9 7.8e-05 22.3 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORX92888.1 - 2.9e-24 83.2 32.0 0.0041 17.1 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 ORX92888.1 - 1.2e-18 66.5 6.4 9.1e-07 28.5 0.2 5.0 2 2 2 4 4 4 4 TPR repeat TPR_14 PF13428.6 ORX92888.1 - 5.6e-18 64.1 12.7 0.001 19.7 0.0 8.9 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORX92888.1 - 5.9e-17 60.4 34.8 2.8e-05 24.0 0.0 9.7 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORX92888.1 - 1.2e-12 48.2 7.4 0.00015 22.3 0.0 6.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORX92888.1 - 3e-11 43.5 15.8 0.0015 18.8 2.1 6.6 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORX92888.1 - 4.7e-11 43.0 10.7 0.12 13.0 0.0 7.2 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX92888.1 - 1.2e-10 41.0 19.0 0.0091 16.3 0.6 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORX92888.1 - 4.3e-08 32.6 18.6 0.43 10.7 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX92888.1 - 0.00011 22.4 25.4 0.011 16.0 0.3 6.2 3 1 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORX92888.1 - 0.00081 19.2 13.6 11 6.0 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX92888.1 - 0.00098 19.6 22.1 3.3 8.5 0.1 8.5 9 1 0 9 9 9 1 Tetratricopeptide repeat ChAPs PF09295.10 ORX92888.1 - 0.0016 17.6 1.8 2.2 7.2 0.0 3.5 1 1 3 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 ORX92888.1 - 0.0042 16.4 5.9 1.3 8.1 0.0 4.7 3 2 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 ORX92888.1 - 3.3 8.2 5.6 3 8.3 2.3 2.7 2 1 0 2 2 1 0 Bacterial transcriptional activator domain Mre11_DNA_bind PF04152.14 ORX92889.1 - 2.6e-48 164.6 3.0 5.9e-48 163.4 0.1 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 ORX92889.1 - 1.2e-15 58.6 0.2 2.8e-15 57.4 0.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX92889.1 - 8.6e-05 22.8 0.0 0.00067 19.9 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain COX5B PF01215.19 ORX92890.1 - 3.2e-45 153.0 0.1 4.3e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C2H2 PF00096.26 ORX92891.1 - 0.0022 18.3 0.1 0.0044 17.4 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX92891.1 - 0.0089 16.8 0.0 0.02 15.7 0.0 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger TALPID3 PF15324.6 ORX92891.1 - 0.048 11.3 9.3 0.057 11.1 9.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target FOXP-CC PF16159.5 ORX92891.1 - 0.22 12.2 0.0 0.42 11.3 0.0 1.4 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF2196 PF09962.9 ORX92892.1 - 1.2e-22 79.6 2.5 1.8e-22 79.0 2.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Rad50_zn_hook PF04423.14 ORX92892.1 - 0.14 12.0 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF3472 PF11958.8 ORX92893.1 - 3.6e-06 27.6 0.3 1.2e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX92893.1 - 0.26 11.2 11.7 0.043 13.7 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) Homeodomain PF00046.29 ORX92905.1 - 3e-17 62.2 7.8 5.6e-17 61.3 7.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX92905.1 - 0.015 15.2 1.4 0.045 13.7 1.4 1.8 1 0 0 1 1 1 0 Homeobox KN domain HTH_32 PF13565.6 ORX92905.1 - 0.054 14.1 0.8 0.1 13.2 0.8 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Terminase_5 PF06056.12 ORX92905.1 - 0.15 11.9 0.1 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Pkinase PF00069.25 ORX92906.1 - 1.3e-47 162.4 0.0 5.2e-24 85.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92906.1 - 4.4e-32 111.4 0.0 9.3e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase POLO_box PF00659.18 ORX92906.1 - 4.6e-18 65.2 0.3 2.7e-08 33.9 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 ORX92906.1 - 0.0076 15.6 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like M16C_assoc PF08367.11 ORX92907.1 - 4e-72 242.4 0.0 6e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 ORX92907.1 - 2.3e-21 76.6 0.1 2.8e-13 50.3 0.0 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORX92907.1 - 1.4e-06 28.4 0.0 5e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RGS PF00615.19 ORX92908.1 - 5.6e-15 55.7 2.6 9.4e-15 54.9 2.6 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain S4 PF01479.25 ORX92909.1 - 1e-12 47.5 1.0 1e-12 47.5 1.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORX92909.1 - 7e-05 23.7 0.1 0.00015 22.6 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain A_deaminase PF00962.22 ORX92910.1 - 1e-120 403.0 0.1 1.4e-120 402.6 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Put_Phosphatase PF06888.12 ORX92911.1 - 3.9e-51 173.7 0.1 4.7e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 ORX92911.1 - 0.0019 18.3 1.2 0.037 14.1 0.5 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX92911.1 - 0.0056 17.1 0.4 0.086 13.2 0.4 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3591 PF12157.8 ORX92912.1 - 1.9e-185 616.7 0.1 3e-185 616.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) TBP-binding PF09247.11 ORX92912.1 - 6.5e-09 35.9 0.8 2.2e-08 34.2 0.8 2.0 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.6 ORX92912.1 - 2e-07 30.7 0.6 4.4e-07 29.6 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 ORX92912.1 - 0.029 14.5 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain zf-CCHC PF00098.23 ORX92912.1 - 0.3 11.2 2.5 0.53 10.4 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle MCM PF00493.23 ORX92913.1 - 5.3e-79 264.5 0.0 9.1e-79 263.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 ORX92913.1 - 8.8e-19 67.7 3.0 1.6e-18 66.9 3.0 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 ORX92913.1 - 1.5e-10 40.8 0.1 6.6e-06 25.7 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_OB PF17207.3 ORX92913.1 - 1.1e-07 31.7 3.3 5.7e-07 29.4 3.3 2.0 1 1 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 ORX92913.1 - 9.4e-07 28.9 0.0 2.5e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORX92913.1 - 0.0033 17.3 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORX92913.1 - 0.029 14.1 0.0 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 ORX92913.1 - 0.046 14.1 0.2 0.13 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX92913.1 - 0.047 14.0 0.3 0.22 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ORX92913.1 - 0.048 14.1 0.1 0.43 11.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 ORX92913.1 - 0.1 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family N-glycanase_N PF09112.10 ORX92913.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal AAA_30 PF13604.6 ORX92913.1 - 0.13 11.9 1.3 0.36 10.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORX92913.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-H2C2_2 PF13465.6 ORX92913.1 - 1.8 9.1 4.0 4.6 7.8 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double domain WD40 PF00400.32 ORX92914.1 - 3.8e-52 173.1 26.8 1.2e-06 29.1 0.1 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX92914.1 - 1.4e-22 79.8 6.8 0.0083 16.4 0.0 8.5 5 3 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 ORX92914.1 - 6.3e-22 77.9 0.3 6.3e-22 77.9 0.3 2.0 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40_like PF17005.5 ORX92914.1 - 1.2e-06 28.0 0.3 1.8 7.8 0.1 4.6 4 1 0 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 ORX92914.1 - 1.5e-06 27.4 3.5 2.2 7.2 0.0 6.3 4 3 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX92914.1 - 5.4e-05 22.0 6.1 0.59 8.7 0.0 5.3 3 2 1 6 6 6 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORX92914.1 - 0.027 13.4 3.4 2.3 7.1 0.1 3.6 5 0 0 5 5 5 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 ORX92914.1 - 0.036 13.3 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ATF7IP_BD PF16788.5 ORX92914.1 - 0.049 13.7 1.9 0.091 12.9 1.9 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain Utp13 PF08625.11 ORX92914.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain FAM178 PF14816.6 ORX92914.1 - 7.9 5.3 10.8 0.16 10.9 2.8 2.1 2 1 0 2 2 2 0 Family of unknown function, FAM178 TPR_2 PF07719.17 ORX92915.1 - 0.0016 18.4 1.4 0.0041 17.1 1.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX92915.1 - 0.0028 17.4 1.6 0.0064 16.3 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box-like PF12937.7 ORX92915.1 - 0.0029 17.5 0.4 0.0056 16.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX92915.1 - 0.0047 16.8 1.5 0.0093 15.8 1.5 1.5 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.6 ORX92915.1 - 0.11 12.8 0.2 0.27 11.5 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX92915.1 - 0.13 11.9 1.9 0.18 11.5 0.4 1.9 1 1 1 2 2 2 0 TPR repeat Rad17 PF03215.15 ORX92916.1 - 6.3e-28 98.0 0.0 1.1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 ORX92916.1 - 1.7e-05 25.3 0.0 0.00012 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX92916.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 ORX92916.1 - 0.0041 16.9 0.4 0.061 13.1 0.3 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 ORX92916.1 - 0.0068 17.0 0.0 0.022 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 ORX92916.1 - 0.0073 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HrcA_DNA-bdg PF03444.15 ORX92916.1 - 0.0076 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding RuvB_N PF05496.12 ORX92916.1 - 0.011 15.5 0.0 0.13 12.0 0.0 2.3 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 ORX92916.1 - 0.016 15.5 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain ABC_tran PF00005.27 ORX92916.1 - 0.019 15.5 0.0 0.049 14.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 ORX92916.1 - 0.026 14.9 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORX92916.1 - 0.037 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORX92916.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORX92916.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORX92916.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L14e PF01929.17 ORX92917.1 - 2.6e-30 104.7 2.5 3.8e-30 104.2 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORX92917.1 - 1.4e-05 24.8 0.1 2.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 KOW motif RabGAP-TBC PF00566.18 ORX92918.1 - 4.1e-28 98.5 0.0 5.7e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Snapin_Pallidin PF14712.6 ORX92920.1 - 1e-06 29.0 0.5 1e-06 29.0 0.5 2.2 2 0 0 2 2 2 1 Snapin/Pallidin FUSC PF04632.12 ORX92920.1 - 0.9 8.0 4.8 1.4 7.3 4.9 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Paramecium_SA PF01508.16 ORX92921.1 - 0.0077 16.6 4.8 4.3 7.8 0.2 3.2 1 1 2 3 3 3 3 Paramecium surface antigen domain RuvC PF02075.17 ORX92921.1 - 0.73 9.7 3.1 3.5 7.5 0.3 2.1 1 1 1 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Peptidase_C14 PF00656.22 ORX92922.1 - 2.6e-56 191.3 0.1 3.9e-56 190.8 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Mito_carr PF00153.27 ORX92923.1 - 2.9e-60 200.2 3.9 5.5e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TTKRSYEDQ PF10212.9 ORX92924.1 - 6.8e-21 74.9 10.8 6.8e-21 74.9 10.8 3.7 2 2 1 4 4 4 1 Predicted coiled-coil domain-containing protein KLRAQ PF10205.9 ORX92924.1 - 1.2e-19 70.4 11.7 1.2e-19 70.4 11.7 5.0 3 2 1 4 4 4 1 Predicted coiled-coil domain-containing protein FliD_C PF07195.12 ORX92924.1 - 0.0016 18.0 4.4 0.0016 18.0 4.4 4.5 4 1 0 4 4 4 1 Flagellar hook-associated protein 2 C-terminus ZapB PF06005.12 ORX92924.1 - 0.017 15.5 4.4 0.017 15.5 4.4 6.6 3 2 1 5 5 5 0 Cell division protein ZapB HAUS-augmin3 PF14932.6 ORX92924.1 - 0.032 13.8 58.6 0.62 9.6 6.0 4.5 4 0 0 4 4 4 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 ORX92924.1 - 0.16 11.3 66.9 0.028 13.8 5.1 5.1 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 ORX92924.1 - 1.3 8.5 62.2 0.019 14.6 5.6 5.2 4 1 1 5 5 5 0 Intermediate filament protein Glyco_hydro_18 PF00704.28 ORX92938.1 - 7.9e-58 196.6 0.3 9.8e-58 196.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FAT PF02259.23 ORX92939.1 - 0.0019 17.5 3.0 0.099 11.8 0.1 2.3 1 1 1 2 2 2 2 FAT domain Fez1 PF06818.15 ORX92939.1 - 0.0065 17.0 1.8 0.0065 17.0 1.8 2.2 2 0 0 2 2 2 1 Fez1 PG_binding_1 PF01471.18 ORX92939.1 - 0.029 14.6 0.1 5 7.4 0.0 3.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain APG6_N PF17675.1 ORX92939.1 - 0.082 13.4 14.0 0.05 14.1 11.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 ORX92939.1 - 0.32 10.2 5.1 0.58 9.3 5.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein HSP70 PF00012.20 ORX92939.1 - 0.33 9.1 3.8 6.1 4.9 0.0 2.1 2 0 0 2 2 2 0 Hsp70 protein Fzo_mitofusin PF04799.13 ORX92939.1 - 0.4 10.2 4.0 1 8.9 4.0 1.7 1 1 0 1 1 1 0 fzo-like conserved region Cor1 PF04803.12 ORX92939.1 - 0.67 10.2 8.7 2.8 8.2 4.6 2.6 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region SlyX PF04102.12 ORX92939.1 - 1.3 9.7 4.6 3.4 8.3 3.8 2.3 1 1 0 1 1 1 0 SlyX Sipho_Gp157 PF05565.11 ORX92939.1 - 3.1 7.8 11.9 0.57 10.2 6.3 2.4 2 1 1 3 3 3 0 Siphovirus Gp157 Pyr_redox_2 PF07992.14 ORX92940.1 - 5.5e-50 170.2 0.0 6.7e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX92940.1 - 4.8e-11 43.1 0.0 2.2e-10 40.9 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX92940.1 - 0.00058 19.2 0.1 0.49 9.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX92940.1 - 0.15 11.6 0.2 9 5.8 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2_5_RNA_ligase2 PF13563.6 ORX92941.1 - 6.3e-35 120.3 0.5 7.3e-35 120.1 0.5 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 ORX92941.1 - 5.4e-07 29.7 0.9 0.019 15.1 0.1 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 ORX92941.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain DUF3040 PF11239.8 ORX92941.1 - 0.074 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) B12D PF06522.11 ORX92942.1 - 0.17 11.7 1.0 0.47 10.3 1.0 1.7 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit YEATS PF03366.16 ORX92943.1 - 7.1e-21 74.0 0.1 1.5e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 YEATS family BET PF17035.5 ORX92943.1 - 4e-06 26.9 0.2 1e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation ECH_2 PF16113.5 ORX92944.1 - 3.8e-27 95.7 0.0 3.7e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Homeobox_KN PF05920.11 ORX92945.1 - 2.9e-20 71.9 0.6 3.6e-20 71.6 0.6 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORX92945.1 - 1.4e-09 37.6 0.1 1.8e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORX92945.1 - 0.11 12.0 0.1 0.22 11.0 0.0 1.6 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Ribosomal_L14 PF00238.19 ORX92946.1 - 3.3e-35 120.8 0.1 4e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e 2-oxoacid_dh PF00198.23 ORX92947.1 - 4.2e-71 239.1 0.2 1.1e-70 237.7 0.2 1.6 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORX92947.1 - 5e-21 74.3 0.6 1.3e-20 73.0 0.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORX92947.1 - 2.8e-11 43.6 0.8 9e-11 41.9 0.1 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORX92947.1 - 0.0076 16.1 0.0 0.033 14.0 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like SUD-M PF11633.8 ORX92947.1 - 0.042 13.5 0.1 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 Single-stranded poly(A) binding domain Glyco_hydro_16 PF00722.21 ORX92948.1 - 7.2e-20 71.2 0.2 9.6e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 ORX92948.1 - 0.0099 14.3 0.3 0.024 13.1 0.3 1.7 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Abhydrolase_3 PF07859.13 ORX92949.1 - 9.5e-20 71.4 0.0 1.5e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORX92949.1 - 2.2e-15 56.5 0.0 1e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 ORX92949.1 - 1.3e-11 44.4 0.5 3.5e-08 33.2 0.1 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ORX92949.1 - 8.2e-07 28.2 0.2 8.4e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ORX92949.1 - 2.6e-05 24.0 0.1 0.23 11.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX92949.1 - 0.00051 20.7 0.0 0.00069 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX92949.1 - 0.00076 18.8 0.7 0.57 9.4 0.1 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 ORX92949.1 - 0.0039 16.9 0.0 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORX92949.1 - 0.0047 16.8 0.0 0.044 13.6 0.1 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 ORX92949.1 - 0.022 14.3 0.6 3.6 7.1 0.1 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.14 ORX92949.1 - 0.025 13.9 0.5 5.5 6.2 0.0 2.4 2 1 0 2 2 2 0 Secretory lipase 2-Hacid_dh_C PF02826.19 ORX92950.1 - 5.1e-53 179.1 0.0 6.7e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORX92950.1 - 9e-18 64.2 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORX92950.1 - 4.6e-05 23.6 0.0 8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORX92950.1 - 0.027 15.1 0.0 0.06 13.9 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 ORX92950.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain RNA_pol_Rpc82 PF05645.13 ORX92951.1 - 3.1e-19 69.7 0.1 1.4e-18 67.6 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 ORX92951.1 - 5.1e-05 23.1 1.3 0.00016 21.5 0.6 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit DUF4988 PF16378.5 ORX92951.1 - 0.026 14.2 0.0 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function TrmB PF01978.19 ORX92951.1 - 0.066 13.1 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2258 PF10015.9 ORX92951.1 - 0.076 13.2 0.3 0.19 11.9 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Opi1 PF08618.10 ORX92951.1 - 0.19 10.9 0.1 0.19 10.9 0.1 1.4 2 0 0 2 2 2 0 Transcription factor Opi1 Cytochrom_B562 PF07361.11 ORX92952.1 - 0.021 15.5 0.9 0.03 15.0 0.9 1.3 1 0 0 1 1 1 0 Cytochrome b562 Hist_deacetyl PF00850.19 ORX92953.1 - 4e-84 282.7 0.0 5e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain CTP_transf_like PF01467.26 ORX92954.1 - 5.5e-30 104.4 0.0 6.7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DnaJ PF00226.31 ORX92955.1 - 3.5e-22 78.3 0.1 1.2e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4917 PF16263.5 ORX92955.1 - 0.015 14.7 0.5 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4917) PGK PF00162.19 ORX92969.1 - 3e-151 503.7 2.0 3.4e-151 503.5 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 ORX92969.1 - 0.0076 16.2 0.0 0.032 14.3 0.0 2.1 1 0 0 1 1 1 1 PA domain PWWP PF00855.17 ORX92970.1 - 2.1e-06 28.1 0.6 0.00011 22.5 1.2 3.2 2 1 0 2 2 2 1 PWWP domain RTC4 PF14474.6 ORX92970.1 - 0.0031 17.7 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 RTC4-like domain DUF4537 PF15057.6 ORX92970.1 - 0.051 13.6 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) MCM2_N PF12619.8 ORX92970.1 - 3.2 8.0 7.3 2.1 8.6 1.3 2.8 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 ATP-synt_E_2 PF08112.11 ORX92971.1 - 0.056 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 ATP synthase epsilon subunit NUDE_C PF04880.13 ORX92971.1 - 3.8 7.9 13.9 3.2 8.2 3.3 2.5 2 1 0 2 2 2 0 NUDE protein, C-terminal conserved region Fungal_trans PF04082.18 ORX92972.1 - 1.4e-23 83.3 0.1 4.2e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX92972.1 - 3.7e-13 49.4 11.5 6.4e-13 48.6 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_6 PF14835.6 ORX92972.1 - 0.23 11.3 1.5 0.5 10.3 1.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4404 PF14357.6 ORX92972.1 - 1.6 9.4 3.5 3.5 8.3 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TRAM_LAG1_CLN8 PF03798.16 ORX92973.1 - 3.4e-36 124.9 24.0 3.4e-36 124.9 24.0 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORX92973.1 - 1.4e-19 69.5 0.3 4e-19 68.0 0.3 1.9 1 0 0 1 1 1 1 TRAM1-like protein Sulfate_transp PF00916.20 ORX92975.1 - 2.9e-105 352.2 24.9 3.7e-105 351.8 24.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX92975.1 - 4.5e-13 48.9 0.0 8.6e-12 44.7 0.0 2.9 2 1 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 ORX92975.1 - 0.00061 20.2 2.7 0.00061 20.2 2.7 3.2 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily Cyclin PF08613.11 ORX92976.1 - 6.7e-07 29.8 0.0 0.00013 22.3 0.0 2.2 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 ORX92976.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Med26 PF08711.11 ORX92977.1 - 7.9e-10 38.6 2.6 1.8e-09 37.5 1.6 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-CCCH_4 PF18044.1 ORX92978.1 - 1e-09 38.0 4.0 1e-09 38.0 4.0 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX92978.1 - 6.1e-08 32.5 6.9 6.1e-08 32.5 6.9 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 ORX92978.1 - 2.8e-07 30.3 4.4 7e-07 29.0 4.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 ORX92978.1 - 0.00084 19.7 4.2 0.0021 18.4 4.2 1.7 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORX92978.1 - 0.0017 19.0 8.1 0.0075 17.0 8.1 2.1 1 1 0 1 1 1 1 Torus domain Baculo_PEP_C PF04513.12 ORX92979.1 - 0.0055 16.7 2.3 0.0099 15.9 2.3 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Hydantoinase_B PF02538.14 ORX92979.1 - 0.012 14.1 1.3 0.012 14.0 0.2 1.4 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase DUF1664 PF07889.12 ORX92979.1 - 0.021 14.9 6.5 0.052 13.6 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S64 PF08192.11 ORX92979.1 - 0.028 12.9 13.0 0.033 12.7 13.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 FANCI_S2 PF14676.6 ORX92979.1 - 0.029 14.7 2.5 0.055 13.8 2.5 1.4 1 0 0 1 1 1 0 FANCI solenoid 2 SlyX PF04102.12 ORX92979.1 - 0.05 14.2 1.4 0.21 12.2 1.4 2.2 1 0 0 1 1 1 0 SlyX Herpes_UL14 PF03580.14 ORX92979.1 - 0.16 12.2 3.4 0.12 12.6 0.5 2.1 2 1 0 2 2 2 0 Herpesvirus UL14-like protein Nup54 PF13874.6 ORX92979.1 - 0.27 11.3 5.3 0.52 10.4 1.6 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Sod_Fe_N PF00081.22 ORX92979.1 - 0.61 10.6 5.4 1.2 9.7 2.1 2.4 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain dCache_2 PF08269.11 ORX92979.1 - 2.9 7.0 6.6 4.3 6.4 0.7 2.2 2 0 0 2 2 2 0 Cache domain OxoGdeHyase_C PF16870.5 ORX92987.1 - 2.1e-49 167.1 0.1 3.8e-49 166.3 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 ORX92987.1 - 1.5e-48 164.8 0.0 2.4e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORX92987.1 - 7.2e-44 149.9 0.1 1.2e-43 149.1 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component ATP-cone PF03477.16 ORX92987.1 - 0.11 13.0 0.1 12 6.6 0.0 2.8 2 0 0 2 2 2 0 ATP cone domain F-box-like PF12937.7 ORX92988.1 - 7e-12 45.0 1.5 1.4e-11 44.1 1.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX92988.1 - 5.3e-09 35.7 2.8 1.7e-08 34.1 2.8 1.9 1 0 0 1 1 1 1 F-box domain OxoGdeHyase_C PF16870.5 ORX92989.1 - 4.5e-49 166.0 0.0 8e-49 165.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 ORX92989.1 - 1.7e-48 164.6 0.0 2.9e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORX92989.1 - 2.5e-43 148.1 0.1 4.4e-43 147.3 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component ATP-cone PF03477.16 ORX92989.1 - 0.12 13.0 0.1 12 6.6 0.0 2.8 2 0 0 2 2 2 0 ATP cone domain F-box-like PF12937.7 ORX92990.1 - 1.3e-10 41.0 2.2 2.4e-10 40.1 2.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX92990.1 - 1.9e-05 24.4 4.0 1.9e-05 24.4 4.0 2.0 2 0 0 2 2 2 1 F-box domain AMP-binding PF00501.28 ORX92991.1 - 1.3e-77 261.2 0.0 1.6e-77 260.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX92991.1 - 2e-12 47.9 0.0 4.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MaoC_dehydratas PF01575.19 ORX92992.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain CHCH PF06747.13 ORX92993.1 - 3.3e-07 30.3 9.7 5e-07 29.7 9.7 1.3 1 0 0 1 1 1 1 CHCH domain NAR2 PF16974.5 ORX92993.1 - 0.0029 17.0 2.2 0.0031 17.0 2.2 1.2 1 0 0 1 1 1 1 High-affinity nitrate transporter accessory DUF3740 PF12548.8 ORX92993.1 - 0.041 14.3 5.9 0.049 14.1 5.9 1.1 1 0 0 1 1 1 0 Sulfatase protein COX17 PF05051.13 ORX92993.1 - 0.13 12.6 3.6 0.23 11.9 3.6 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 ORX92993.1 - 0.46 10.5 7.8 0.22 11.6 2.7 2.2 1 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ThiF PF00899.21 ORX92994.1 - 2.6e-42 144.9 0.0 3.1e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORX92994.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 ORX92994.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding HAD_2 PF13419.6 ORX92995.1 - 7.3e-27 94.6 0.0 8.7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX92995.1 - 1.3e-17 64.8 0.1 1.7e-15 57.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX92995.1 - 2.6e-05 24.7 0.0 3.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORX92995.1 - 4.2e-05 23.6 0.0 0.025 14.7 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX92995.1 - 0.00019 21.5 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HMG_box PF00505.19 ORX92996.1 - 2.4e-24 85.5 2.2 2.6e-24 85.4 2.2 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX92996.1 - 2.2e-12 47.4 1.0 2.3e-12 47.3 1.0 1.0 1 0 0 1 1 1 1 HMG-box domain Ntox43 PF15537.6 ORX92996.1 - 0.064 13.3 0.0 0.33 11.0 0.0 1.8 1 1 1 2 2 2 0 Bacterial toxin 43 CCAP PF11105.8 ORX92996.1 - 0.065 13.2 0.4 0.11 12.4 0.3 1.4 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a HTH_24 PF13412.6 ORX92996.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Pkinase PF00069.25 ORX92997.1 - 3.1e-32 112.0 2.5 9.2e-27 94.0 1.2 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX92997.1 - 3.7e-15 55.9 1.1 9.9e-15 54.5 0.4 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORX92997.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORX92997.1 - 0.054 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Histone PF00125.24 ORX92998.1 - 4.4e-51 172.7 2.0 4.9e-51 172.5 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX92998.1 - 1.7e-05 25.1 0.0 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX92998.1 - 3.5e-05 23.9 0.0 6.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORX92998.1 - 0.0077 16.8 2.4 0.0099 16.5 2.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORX92998.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX92998.1 - 0.064 13.3 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX92998.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated zf-C3HC4_3 PF13920.6 ORX92999.1 - 1.2e-08 34.6 5.1 2.3e-08 33.8 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX92999.1 - 1.8e-08 34.2 6.2 5e-08 32.8 6.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH PF00642.24 ORX92999.1 - 2.5e-08 33.6 1.8 6.8e-08 32.2 1.8 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 ORX92999.1 - 1e-06 28.6 9.1 1.9e-06 27.8 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORX92999.1 - 1.2e-06 28.2 8.2 2.5e-06 27.2 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX92999.1 - 2.8e-06 27.1 8.8 6.3e-06 26.0 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX92999.1 - 1.1e-05 25.6 7.5 2.5e-05 24.5 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 ORX92999.1 - 5.7e-05 23.0 3.1 5.7e-05 23.0 3.1 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-RING_10 PF16685.5 ORX92999.1 - 0.00056 20.0 3.3 0.00056 20.0 3.3 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ORX92999.1 - 0.0013 18.9 7.5 0.0013 18.9 7.5 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORX92999.1 - 0.0095 15.8 6.6 0.018 14.9 6.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 ORX92999.1 - 0.027 15.0 1.6 0.079 13.5 1.6 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ORX92999.1 - 0.039 13.8 2.1 0.039 13.8 2.1 2.2 3 0 0 3 3 2 0 CCCH-type zinc finger zf-Nse PF11789.8 ORX92999.1 - 0.14 12.0 3.2 0.28 11.0 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.18 ORX92999.1 - 5.4 6.4 8.8 0.097 12.0 1.8 1.8 2 0 0 2 2 1 0 Zn-finger in Ran binding protein and others AATF-Che1 PF13339.6 ORX93000.1 - 5.1e-35 121.2 0.6 5.1e-35 121.2 0.6 3.8 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 ORX93000.1 - 8.8e-31 106.3 0.1 8.8e-31 106.3 0.1 3.5 4 1 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal RNA_pol_Rpb1_6 PF04992.14 ORX93000.1 - 9 6.1 17.2 4.3 7.1 5.8 2.8 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 6 UCH PF00443.29 ORX93001.1 - 8.9e-48 163.0 0.0 1.3e-41 142.9 0.0 3.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORX93001.1 - 1.1e-15 58.1 1.3 1.9e-15 57.3 0.1 2.2 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 ORX93001.1 - 2.5e-07 30.6 4.5 0.003 17.2 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF1754 PF08555.10 ORX93001.1 - 6.5e-05 23.7 21.1 0.049 14.4 13.4 2.6 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) USP7_C2 PF14533.6 ORX93001.1 - 0.0013 18.4 0.1 0.014 15.1 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UN_NPL4 PF11543.8 ORX93001.1 - 0.15 12.6 0.1 1.6 9.3 0.0 2.7 3 1 0 3 3 3 0 Nuclear pore localisation protein NPL4 zf-H2C2_2 PF13465.6 ORX93001.1 - 0.15 12.5 1.1 29 5.3 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF4662 PF15578.6 ORX93001.1 - 1 9.1 4.3 2.5 7.9 4.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) bZIP_1 PF00170.21 ORX93002.1 - 2.7e-12 46.6 9.0 4e-12 46.1 9.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX93002.1 - 4.1e-06 26.8 7.7 4.1e-06 26.8 7.7 1.6 2 0 0 2 2 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 ORX93002.1 - 9e-05 22.8 4.8 9.6e-05 22.7 2.6 2.2 1 1 1 2 2 2 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 ORX93002.1 - 0.00024 21.4 3.4 0.00024 21.4 3.4 2.8 3 1 1 4 4 4 1 Aft1 HRA domain bZIP_Maf PF03131.17 ORX93002.1 - 0.0004 20.9 4.2 0.0007 20.1 4.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 ORX93002.1 - 0.0049 17.3 0.3 0.0085 16.5 0.3 1.4 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 ORX93002.1 - 0.029 14.6 1.5 0.052 13.8 1.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pax7 PF12360.8 ORX93002.1 - 0.061 13.5 0.3 0.061 13.5 0.3 3.1 4 0 0 4 4 4 0 Paired box protein 7 DUF2383 PF09537.10 ORX93002.1 - 0.077 13.3 0.5 0.14 12.5 0.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF2383) GIT_CC PF16559.5 ORX93002.1 - 0.12 12.3 2.4 0.26 11.2 2.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CDC48_2 PF02933.17 ORX93002.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DivIC PF04977.15 ORX93002.1 - 0.22 11.3 2.7 0.37 10.6 2.7 1.3 1 0 0 1 1 1 0 Septum formation initiator ATF7IP_BD PF16788.5 ORX93002.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.4 2 0 0 2 2 2 0 ATF-interacting protein binding domain LigB PF02900.18 ORX93003.1 - 1e-41 142.8 0.0 1.2e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Metallophos_C PF14008.6 ORX93003.1 - 0.00027 21.7 0.1 0.00061 20.6 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C GPI-anchored PF10342.9 ORX93004.1 - 2.4e-15 57.0 0.1 3.2e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Doppel PF11466.8 ORX93004.1 - 0.32 10.7 2.9 0.73 9.5 2.9 1.5 1 0 0 1 1 1 0 Prion-like protein Doppel GPI-anchored PF10342.9 ORX93005.1 - 7.5e-16 58.7 0.1 1.5e-15 57.7 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cytochrom_C1 PF02167.15 ORX93006.1 - 6.7e-98 326.8 0.0 8.2e-98 326.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORX93006.1 - 0.00091 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORX93006.1 - 0.025 15.7 0.1 0.084 14.0 0.0 2.0 2 1 0 2 2 2 0 Cytochrome c Arylesterase PF01731.20 ORX93007.1 - 2.3e-07 30.9 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 ORX93007.1 - 0.038 13.6 0.0 0.056 13.0 0.0 1.3 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region OxoGdeHyase_C PF16870.5 ORX93009.1 - 1e-49 168.2 0.1 1.8e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 ORX93009.1 - 1.4e-48 164.9 0.0 2.3e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORX93009.1 - 1.2e-42 145.9 0.0 2.1e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component adh_short PF00106.25 ORX93010.1 - 1.4e-28 99.7 0.0 7.3e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93010.1 - 1.5e-18 67.3 0.0 6.5e-17 61.9 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93010.1 - 9.6e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX93010.1 - 0.00061 19.3 0.0 0.0074 15.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORX93010.1 - 0.032 14.1 0.0 0.18 11.7 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding Uricase PF01014.18 ORX93025.1 - 3.6e-64 214.9 3.0 9.2e-37 126.2 1.1 2.0 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORX93026.1 - 1.3e-60 203.4 0.6 8.1e-35 119.9 0.2 2.1 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORX93027.1 - 3e-64 215.1 2.7 9.2e-37 126.2 1.1 2.0 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORX93028.1 - 7e-61 204.3 0.9 5.3e-35 120.5 0.3 2.1 2 0 0 2 2 2 2 Uricase EXOSC1 PF10447.9 ORX93029.1 - 1.6e-19 70.5 3.0 8.8e-15 55.3 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 ORX93029.1 - 4.2e-11 42.4 0.2 1.1e-10 41.2 0.1 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 ORX93029.1 - 0.0046 17.7 0.1 0.007 17.1 0.1 1.4 1 1 0 1 1 1 1 Penicillin-binding protein OB-like domain S1 PF00575.23 ORX93029.1 - 0.017 15.4 0.8 0.14 12.6 0.8 2.2 1 1 0 1 1 1 0 S1 RNA binding domain CM_1 PF07736.11 ORX93029.1 - 0.022 15.1 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Chorismate mutase type I AAA PF00004.29 ORX93030.1 - 8.7e-26 90.9 0.7 1.3e-22 80.6 0.7 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORX93030.1 - 3.8e-18 65.2 0.0 7.5e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORX93030.1 - 5.5e-10 38.9 0.3 5.5e-10 38.9 0.3 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 ORX93030.1 - 0.00042 20.3 1.4 0.0023 17.9 0.1 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORX93030.1 - 0.0011 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 ORX93030.1 - 0.0013 18.2 0.1 0.0076 15.7 0.1 2.1 1 1 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 ORX93030.1 - 0.0019 18.6 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORX93030.1 - 0.0049 17.0 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORX93030.1 - 0.0049 16.3 0.1 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORX93030.1 - 0.017 15.6 0.1 0.085 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORX93030.1 - 0.021 15.1 0.1 0.058 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORX93030.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 ORX93030.1 - 0.028 14.2 0.3 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORX93030.1 - 0.029 14.1 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 ORX93030.1 - 0.034 13.5 0.6 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 ORX93030.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORX93030.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORX93030.1 - 0.09 12.0 0.2 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 ORX93030.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 ORX93030.1 - 0.12 11.9 1.8 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ORX93030.1 - 0.12 12.8 0.8 0.8 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORX93030.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF3535 PF12054.8 ORX93031.1 - 4.5e-114 382.1 0.2 3.2e-110 369.4 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.23 ORX93031.1 - 4.2e-65 219.8 0.3 9.3e-65 218.6 0.2 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX93031.1 - 1.1e-16 61.1 0.0 4.5e-16 59.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 ORX93031.1 - 1.6e-16 58.9 12.7 0.028 14.7 0.7 11.2 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.7 ORX93031.1 - 3.4e-08 34.0 0.5 0.036 14.7 0.0 4.6 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORX93031.1 - 2e-07 31.3 15.2 0.0049 17.3 0.1 9.1 9 1 1 10 10 9 2 HEAT-like repeat TAF6_C PF07571.13 ORX93031.1 - 5.1e-05 23.5 0.0 2.7 8.4 0.1 5.0 5 1 0 5 5 5 2 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 ORX93031.1 - 0.00025 21.4 8.0 0.053 13.9 0.1 6.9 8 1 0 8 8 8 1 HEAT repeats DUF3385 PF11865.8 ORX93031.1 - 0.071 13.0 1.7 0.86 9.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) ERCC3_RAD25_C PF16203.5 ORX93031.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Mak16 PF04874.14 ORX93031.1 - 1.5 9.4 5.6 0.63 10.7 1.7 2.5 2 0 0 2 2 1 0 Mak16 protein C-terminal region Coiled-coil_56 PF09813.9 ORX93032.1 - 1.3e-06 28.4 0.0 1.6e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Thiolase_N PF00108.23 ORX93033.1 - 2.4e-96 322.1 5.5 3e-96 321.8 5.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORX93033.1 - 2.6e-41 140.1 0.3 2.6e-41 140.1 0.3 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORX93033.1 - 2.6e-05 23.9 2.6 0.00098 18.8 1.6 2.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORX93033.1 - 4.2 7.3 7.8 7 6.6 0.4 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FliJ PF02050.16 ORX93034.1 - 0.73 10.1 2.5 0.88 9.8 0.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Rad50_zn_hook PF04423.14 ORX93035.1 - 0.0068 16.2 0.4 0.0092 15.8 0.4 1.2 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-MIZ PF02891.20 ORX93035.1 - 0.072 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-MIZ PF02891.20 ORX93036.1 - 3.1e-05 23.6 2.0 4.6e-05 23.1 0.6 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORX93036.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Bin3 PF06859.12 ORX93037.1 - 1.6e-40 138.1 0.0 3.8e-40 136.9 0.0 1.7 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 ORX93037.1 - 3.6e-11 43.1 0.1 5.1e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX93037.1 - 1.1e-10 41.6 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX93037.1 - 4.9e-10 40.1 0.0 1.5e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORX93037.1 - 3e-08 33.7 0.0 5.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93037.1 - 1.3e-07 32.2 0.0 4.2e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX93037.1 - 1.2e-06 29.0 0.0 4.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORX93037.1 - 1.9e-05 24.2 0.0 8.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 ORX93037.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ORX93037.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 ORX93037.1 - 0.0035 16.3 0.0 0.0055 15.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 ORX93037.1 - 0.0041 16.9 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Spermine_synth PF01564.17 ORX93037.1 - 0.012 15.1 0.0 0.031 13.7 0.0 1.8 1 1 0 1 1 1 0 Spermine/spermidine synthase domain CMAS PF02353.20 ORX93037.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 ORX93037.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 ORX93037.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF43 PF01861.16 ORX93037.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain NodS PF05401.11 ORX93037.1 - 0.17 11.5 0.0 0.79 9.3 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein S (NodS) Per1 PF04080.13 ORX93038.1 - 2.8e-101 338.6 9.0 3.6e-101 338.2 9.0 1.1 1 0 0 1 1 1 1 Per1-like family 7TMR-DISM_7TM PF07695.11 ORX93038.1 - 1.2 9.0 11.9 0.87 9.4 10.1 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling Pam16 PF03656.13 ORX93039.1 - 1.9e-35 121.6 4.6 2.3e-35 121.3 4.6 1.2 1 0 0 1 1 1 1 Pam16 RasGEF PF00617.19 ORX93040.1 - 4.4e-61 206.2 1.4 1.2e-60 204.7 0.1 2.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 ORX93040.1 - 1.8e-25 89.2 0.1 6e-25 87.5 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 ORX93040.1 - 9.1e-17 60.4 0.1 1.8e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX93040.1 - 2.2e-13 49.7 0.0 5.1e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORX93040.1 - 1.6e-10 40.7 0.2 5.2e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 ORX93040.1 - 4.1e-09 36.4 9.1 0.00044 20.3 3.5 2.6 2 0 0 2 2 2 2 WW domain GIT1_C PF12205.8 ORX93040.1 - 0.27 11.3 1.5 5.5 7.1 0.3 2.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Sec2p PF06428.11 ORX93041.1 - 7.3e-18 64.3 9.4 1.4e-17 63.5 9.4 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 ORX93041.1 - 0.0028 15.7 2.2 0.0036 15.3 2.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Rabaptin PF03528.15 ORX93041.1 - 0.029 13.1 6.7 0.043 12.5 6.7 1.1 1 0 0 1 1 1 0 Rabaptin DUF5082 PF16888.5 ORX93041.1 - 0.12 12.7 5.2 0.72 10.1 5.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 ORX93041.1 - 0.26 10.8 2.4 0.37 10.3 2.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 ORX93041.1 - 0.45 9.1 3.2 0.67 8.5 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4211 PF13926.6 ORX93041.1 - 0.49 10.5 2.7 0.56 10.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4211) Tropomyosin_1 PF12718.7 ORX93041.1 - 0.99 9.5 12.2 1.7 8.8 12.2 1.3 1 0 0 1 1 1 0 Tropomyosin like PDEase_I PF00233.19 ORX93042.1 - 2.4e-69 233.7 0.3 4.7e-69 232.7 0.3 1.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 ORX93042.1 - 9.6e-05 22.5 0.0 0.0052 16.9 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HD PF01966.22 ORX93042.1 - 0.056 13.7 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 HD domain PUF PF00806.19 ORX93043.1 - 8.1e-25 85.1 1.8 0.0054 16.4 0.0 8.2 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat ADH_zinc_N PF00107.26 ORX93044.1 - 9.9e-27 93.5 0.0 1.7e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX93044.1 - 6e-18 66.2 0.0 1e-17 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX93044.1 - 1.3e-10 41.1 0.3 8.1e-10 38.6 0.1 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORX93044.1 - 0.003 17.5 0.1 0.0057 16.5 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Glyco_transf_24 PF18404.1 ORX93045.1 - 1.4e-151 503.4 0.4 5.5e-151 501.4 0.5 1.9 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 ORX93045.1 - 1.1e-58 199.2 0.1 3e-58 197.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 ORX93045.1 - 2.9e-42 144.7 0.4 2.9e-42 144.7 0.4 2.3 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 ORX93045.1 - 2.2e-41 140.4 0.0 5.4e-41 139.1 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 ORX93045.1 - 9.9e-39 133.5 2.3 3.5e-33 115.3 0.0 3.1 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 ORX93045.1 - 2.2e-35 121.5 0.4 1.6e-33 115.5 0.8 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 ORX93045.1 - 1.4e-05 24.8 0.1 3.3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_M23 PF01551.22 ORX93046.1 - 0.25 11.6 2.1 3.1 8.1 0.1 2.8 2 1 1 3 3 3 0 Peptidase family M23 Dicty_CAR PF05462.11 ORX93048.1 - 3.4e-14 52.7 19.5 4.4e-14 52.3 19.5 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORX93048.1 - 8.4e-07 28.6 13.1 1.1e-06 28.2 12.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 ORX93048.1 - 0.087 11.9 16.5 0.014 14.4 10.0 2.1 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region Git3 PF11710.8 ORX93048.1 - 3.5 7.3 20.2 0.62 9.8 16.2 1.8 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 TMEMspv1-c74-12 PF11044.8 ORX93048.1 - 8.3 6.5 6.1 1.2 9.1 0.9 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GPR_Gpa2_C PF11970.8 ORX93049.1 - 0.0022 18.0 2.1 0.0022 18.0 2.1 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Bac_export_2 PF01312.19 ORX93049.1 - 0.17 11.1 11.7 0.01 15.0 5.1 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Skp1 PF01466.19 ORX93050.1 - 7.3e-30 102.8 0.9 1.2e-29 102.2 0.9 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORX93050.1 - 8.7e-24 83.5 0.3 2.5e-23 82.0 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ribosomal_L15e PF00827.17 ORX93051.1 - 1.4e-90 302.1 9.7 1.7e-90 301.9 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Coprogen_oxidas PF01218.18 ORX93052.1 - 8.1e-136 451.5 0.1 1e-135 451.2 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF3552 PF12072.8 ORX93052.1 - 0.043 13.2 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Brix PF04427.18 ORX93053.1 - 1.9e-33 116.2 0.6 2.5e-33 115.8 0.6 1.2 1 0 0 1 1 1 1 Brix domain Inhibitor_I53 PF11714.8 ORX93053.1 - 0.12 12.6 0.7 0.22 11.7 0.7 1.4 1 0 0 1 1 1 0 Thrombin inhibitor Madanin YabA PF06156.13 ORX93053.1 - 0.36 11.5 2.4 0.46 11.1 0.9 1.9 2 0 0 2 2 2 0 Initiation control protein YabA DUF2039 PF10217.9 ORX93054.1 - 3.1e-23 81.9 22.4 1.1e-15 57.7 3.6 2.2 1 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 ORX93054.1 - 0.32 11.0 9.7 5 7.2 7.5 2.2 2 0 0 2 2 2 0 zinc-ribbons DUF4746 PF15928.5 ORX93054.1 - 0.73 9.2 5.3 1.1 8.6 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 ORX93054.1 - 0.9 7.8 5.7 1 7.6 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 ORX93054.1 - 5.8 5.6 6.4 8 5.2 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 ORX93054.1 - 7.6 7.0 10.5 1.1 9.7 6.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 ORX93054.1 - 9.2 6.7 10.6 15 6.0 10.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNF220 PF15926.5 ORX93055.1 - 1.1e-26 94.0 9.3 5.2e-26 91.8 9.3 2.0 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 ORX93055.1 - 3e-11 43.0 10.5 3e-11 43.0 10.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX93055.1 - 0.00018 21.4 14.5 0.00024 21.0 11.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORX93055.1 - 0.00038 20.2 15.1 0.0016 18.2 12.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX93055.1 - 0.00064 20.0 11.7 0.00064 20.0 11.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORX93055.1 - 0.0012 18.7 9.2 0.0012 18.7 9.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORX93055.1 - 0.021 14.7 4.2 0.043 13.7 4.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 ORX93055.1 - 0.022 14.8 8.4 0.063 13.3 8.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX93055.1 - 0.19 11.8 8.1 0.16 12.0 5.2 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF515 PF04415.12 ORX93055.1 - 0.27 9.6 4.8 0.43 8.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-Nse PF11789.8 ORX93055.1 - 0.53 10.1 5.4 1.1 9.2 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 ORX93055.1 - 0.67 9.9 15.3 0.45 10.4 12.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORX93055.1 - 5.7 7.3 13.5 2 8.8 8.2 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORX93055.1 - 6 7.1 13.1 1.6 8.9 9.5 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING S10_plectin PF03501.15 ORX93056.1 - 1.6e-47 159.5 0.1 2e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORX93056.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 ORX93056.1 - 0.074 13.1 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Kinase-like PF14531.6 ORX93056.1 - 0.075 12.3 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4364 PF14277.6 ORX93056.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2250 PF10007.9 ORX93056.1 - 0.19 11.8 1.0 4.3 7.5 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Methyltransf_28 PF02636.17 ORX93057.1 - 4.7e-76 255.9 0.0 6.1e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_L3 PF00297.22 ORX93058.1 - 5.6e-188 624.5 9.8 6.3e-188 624.3 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 V-ATPase_G PF03179.15 ORX93059.1 - 5.3e-31 107.3 18.4 6.1e-31 107.1 18.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 ORX93059.1 - 0.0046 17.4 18.5 0.27 11.7 2.9 2.6 1 1 1 2 2 2 2 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.18 ORX93059.1 - 0.0049 16.3 14.7 0.0054 16.2 14.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3552 PF12072.8 ORX93059.1 - 0.0052 16.2 15.7 0.0065 15.9 15.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 ORX93059.1 - 0.0068 16.5 12.9 0.0068 16.5 12.9 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) OMS28_porin PF03532.13 ORX93059.1 - 0.027 13.7 5.1 0.033 13.4 5.1 1.2 1 0 0 1 1 1 0 OMS28 porin Sds3 PF08598.11 ORX93059.1 - 0.16 11.9 8.1 0.44 10.5 7.9 1.6 1 1 1 2 2 2 0 Sds3-like DUF515 PF04415.12 ORX93059.1 - 0.59 8.5 8.5 0.66 8.3 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SAM_Exu PF18609.1 ORX93059.1 - 0.72 10.0 4.2 0.57 10.3 0.3 2.4 1 1 0 2 2 2 0 Exuperantia SAM-like domain CENP-I PF07778.11 ORX93059.1 - 1.5 7.4 6.9 1.8 7.2 6.9 1.0 1 0 0 1 1 1 0 Mis6 UQ_con PF00179.26 ORX93060.1 - 3.9e-42 143.2 0.0 4.4e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 ORX93060.1 - 0.0045 15.9 0.1 0.007 15.2 0.1 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Prok-E2_B PF14461.6 ORX93060.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 ORX93060.1 - 0.13 12.5 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 RWD domain Acetyltransf_1 PF00583.25 ORX93061.1 - 4.2e-14 52.8 0.0 5.5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX93061.1 - 4.1e-11 42.9 0.0 5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX93061.1 - 4.2e-09 36.7 0.3 1.1e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX93061.1 - 1.5e-08 34.5 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORX93061.1 - 0.0074 16.4 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX93061.1 - 0.0088 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GCV_T PF01571.21 ORX93062.1 - 1.3e-86 290.2 0.0 1.8e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORX93062.1 - 2.9e-21 75.2 0.1 5.4e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 ORX93062.1 - 2e-05 24.8 0.4 0.0012 19.0 0.0 2.7 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family DUF3659 PF12396.8 ORX93062.1 - 0.13 12.2 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) UQ_con PF00179.26 ORX93063.1 - 2.5e-43 147.1 0.0 2.8e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ORX93063.1 - 0.00095 18.8 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_E PF14462.6 ORX93063.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family E Prok-E2_B PF14461.6 ORX93063.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Arrestin_C PF02752.22 ORX93064.1 - 2.1e-07 31.5 0.3 0.00014 22.3 0.1 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX93064.1 - 0.014 15.4 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX93064.1 - 0.015 15.0 0.1 0.076 12.7 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like AMP-binding PF00501.28 ORX93065.1 - 7.9e-106 354.2 0.0 1.1e-105 353.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Tyr-DNA_phospho PF06087.12 ORX93066.1 - 3.8e-38 131.5 0.0 4.9e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ApbA PF02558.16 ORX93067.1 - 9.1e-35 119.5 0.0 1.7e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORX93067.1 - 1.5e-28 99.5 0.3 2.6e-28 98.7 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal UDPG_MGDP_dh_N PF03721.14 ORX93067.1 - 0.042 13.4 1.1 0.61 9.6 0.0 2.8 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mannitol_dh_C PF08125.13 ORX93067.1 - 0.078 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain LPMO_10 PF03067.15 ORX93068.1 - 3.9e-06 27.7 0.0 2.8e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX93068.1 - 0.003 17.5 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_14 PF01607.24 ORX93068.1 - 0.9 9.7 7.2 0.82 9.9 5.2 2.0 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain PPR_2 PF13041.6 ORX93071.1 - 9.5e-71 233.8 22.0 1.7e-11 44.1 0.7 12.5 5 2 9 14 14 14 12 PPR repeat family PPR PF01535.20 ORX93071.1 - 3.2e-49 161.8 26.5 1.2e-08 34.6 0.1 14.8 15 1 0 15 15 15 7 PPR repeat PPR_1 PF12854.7 ORX93071.1 - 2.7e-44 148.5 5.7 1.7e-09 37.2 0.0 12.2 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.6 ORX93071.1 - 2.2e-43 146.1 8.9 5.4e-12 45.6 0.0 9.0 5 3 4 9 9 9 9 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX93071.1 - 1.2e-31 109.8 3.5 7.7e-11 41.8 0.1 5.3 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX93071.1 - 6.3e-08 32.8 0.0 22 6.2 0.0 8.0 7 1 2 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX93071.1 - 6.5e-07 28.9 0.7 5.5 7.3 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat RPM2 PF08579.11 ORX93071.1 - 2.8e-05 24.5 1.9 7.5 7.0 0.1 5.6 3 1 1 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX93071.1 - 0.00056 18.9 0.3 0.43 9.4 0.1 3.7 2 2 1 3 3 3 1 Mitochondrial 28S ribosomal protein S27 TPR_1 PF00515.28 ORX93071.1 - 0.001 18.8 5.6 6.9 6.7 0.1 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 ORX93071.1 - 0.038 13.9 9.4 7 6.5 0.0 6.0 5 2 0 6 6 6 0 Region in Clathrin and VPS V-SNARE PF05008.15 ORX93071.1 - 0.08 13.3 0.5 12 6.4 0.1 3.8 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TPR_16 PF13432.6 ORX93071.1 - 0.085 13.5 4.0 20 5.9 0.4 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat CARD PF00619.21 ORX93071.1 - 0.09 12.8 0.1 0.44 10.6 0.1 2.3 1 0 0 1 1 1 0 Caspase recruitment domain TPR_2 PF07719.17 ORX93071.1 - 0.093 12.9 6.7 8.4 6.8 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 ORX93071.1 - 0.096 13.1 3.1 12 6.3 0.0 4.6 5 0 0 5 5 5 0 Bacterial transcriptional activator domain TPR_8 PF13181.6 ORX93071.1 - 1.3 9.4 6.6 1.3e+02 3.1 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat IATP PF04568.12 ORX93072.1 - 6.2e-09 36.2 2.2 7.5e-09 35.9 2.2 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Nudix_N_2 PF14803.6 ORX93073.1 - 0.04 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Nudix N-terminal Cupin_2 PF07883.11 ORX93073.1 - 0.21 11.4 0.0 4.3 7.1 0.0 2.2 2 1 0 2 2 2 0 Cupin domain Pkinase PF00069.25 ORX93074.1 - 1.2e-44 152.6 0.1 1.2e-22 80.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93074.1 - 6.5e-14 51.8 0.2 1.3e-09 37.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX93074.1 - 0.44 9.3 3.6 0.35 9.6 0.1 2.2 1 1 1 3 3 3 0 Fungal protein kinase Mito_carr PF00153.27 ORX93075.1 - 9e-63 208.3 0.6 1.9e-19 69.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX93075.1 - 0.006 15.8 0.2 0.044 12.9 0.0 2.2 2 1 0 2 2 2 1 Gammaproteobacterial serine protease DUF4235 PF14019.6 ORX93075.1 - 0.0099 15.9 0.2 0.51 10.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4235) Amidinotransf PF02274.17 ORX93077.1 - 9e-13 48.0 0.1 3.3e-11 42.9 0.1 2.1 1 1 0 1 1 1 1 Amidinotransferase Gp45_2 PF17470.2 ORX93077.1 - 0.37 10.8 1.2 0.55 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage gene product 45.2 Abhydrolase_3 PF07859.13 ORX93078.1 - 4.2e-41 141.1 0.0 3e-40 138.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX93078.1 - 4.2e-14 52.2 0.0 1.3e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 ORX93078.1 - 0.0076 16.1 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORX93078.1 - 0.038 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 ORX93078.1 - 0.11 11.4 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Carboxylesterase family Alanine_zipper PF11839.8 ORX93078.1 - 0.24 11.8 1.0 0.43 11.0 1.0 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein TPR_16 PF13432.6 ORX93079.1 - 0.00069 20.2 0.1 0.017 15.8 0.2 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX93079.1 - 0.022 15.3 0.4 0.049 14.1 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORX93079.1 - 0.024 15.4 0.9 14 6.9 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX93079.1 - 0.086 13.0 2.1 18 5.8 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 ORX93080.1 - 1.4e-87 293.4 2.5 2.9e-36 125.2 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.7 ORX93080.1 - 7.1e-50 169.9 2.5 7.1e-50 169.9 2.5 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 ORX93080.1 - 1.2e-45 155.8 2.1 2.3e-19 69.7 0.0 4.5 5 0 0 5 5 5 3 Protein tyrosine kinase RWD PF05773.22 ORX93080.1 - 2.2e-18 66.6 0.3 2.2e-18 66.6 0.3 3.0 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.6 ORX93080.1 - 3.5e-12 46.2 0.1 1.8e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 ORX93080.1 - 6e-06 26.3 0.0 0.00044 20.3 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORX93080.1 - 0.0087 15.1 0.2 0.55 9.2 0.0 2.4 2 0 0 2 2 2 1 Seadornavirus VP7 HP_OMP PF01856.17 ORX93080.1 - 0.049 13.7 2.1 1.9 8.5 0.3 3.0 3 0 0 3 3 3 0 Helicobacter outer membrane protein DUF2407 PF10302.9 ORX93080.1 - 0.37 11.4 2.7 53 4.5 3.2 3.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF3381 PF11861.8 ORX93080.1 - 0.43 10.4 12.0 2.1 8.1 12.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Atg14 PF10186.9 ORX93080.1 - 4.2 6.4 10.4 8.5 5.4 10.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Metallophos PF00149.28 ORX93081.1 - 9.1e-36 124.3 0.0 1.3e-35 123.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX93081.1 - 7.4e-17 61.5 0.0 1.9e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Lipase_GDSL PF00657.22 ORX93082.1 - 1.8e-07 31.3 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORX93082.1 - 0.00016 22.1 0.2 0.00037 20.9 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-C2H2 PF00096.26 ORX93083.1 - 7.2e-11 41.9 11.6 2.5e-05 24.5 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93083.1 - 1.8e-09 37.6 9.5 0.00024 21.7 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX93083.1 - 4.9e-09 36.2 12.9 2.1e-07 31.0 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORX93083.1 - 7.9e-05 22.9 1.3 7.9e-05 22.9 1.3 2.2 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX93083.1 - 0.0006 20.0 1.0 0.0006 20.0 1.0 2.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX93083.1 - 0.0016 18.4 9.4 0.0035 17.3 1.8 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX93083.1 - 0.002 18.4 1.6 0.0034 17.7 1.2 1.5 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX93083.1 - 0.0037 17.0 7.9 0.21 11.4 1.2 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORX93083.1 - 0.012 15.9 1.7 0.024 15.0 0.9 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX93083.1 - 0.019 14.7 7.7 0.24 11.2 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 ORX93083.1 - 0.026 14.5 4.7 0.16 12.0 1.8 2.2 1 1 1 2 2 2 0 BED zinc finger Ribosomal_L40e PF01020.17 ORX93083.1 - 0.092 12.7 2.7 4.8 7.2 2.7 2.2 1 1 0 1 1 1 0 Ribosomal L40e family zf-C2HC_2 PF13913.6 ORX93083.1 - 0.19 11.7 3.9 0.53 10.2 0.8 2.3 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Isochorismatase PF00857.20 ORX93084.1 - 4.9e-40 137.5 0.0 5.7e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family WH2 PF02205.20 ORX93085.1 - 9.8e-11 41.1 0.3 2.5e-10 39.8 0.3 1.8 1 0 0 1 1 1 1 WH2 motif Methyltransf_16 PF10294.9 ORX93086.1 - 4.4e-07 29.8 0.0 0.0074 16.0 0.0 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 ORX93086.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX93086.1 - 2.3e-05 24.2 0.3 0.0002 21.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX93086.1 - 0.00031 21.4 0.0 0.0024 18.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93086.1 - 0.0024 18.5 0.0 0.52 11.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX93086.1 - 0.0088 16.7 0.0 0.26 12.0 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Baculo_p47 PF05112.12 ORX93086.1 - 0.035 13.7 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Baculovirus P47 protein MTS PF05175.14 ORX93086.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain UNC-93 PF05978.16 ORX93087.1 - 2.8e-11 43.4 4.6 1e-10 41.5 4.6 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX93087.1 - 9.2e-10 38.0 33.8 9.3e-10 37.9 30.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX93088.1 - 2.8e-11 43.4 4.6 1e-10 41.5 4.6 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX93088.1 - 9.2e-10 38.0 33.8 9.3e-10 37.9 30.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORX93089.1 - 1.3e-11 44.0 23.9 1.3e-11 44.0 23.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX93089.1 - 2.4e-10 40.4 4.5 8.5e-10 38.6 4.5 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 UNC-93 PF05978.16 ORX93090.1 - 3.9e-10 39.7 3.5 3.9e-10 39.7 3.5 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORX93090.1 - 4.9e-09 35.6 28.7 4.9e-09 35.6 28.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily O-FucT PF10250.9 ORX93091.1 - 1.5e-19 71.0 0.9 2.7e-18 66.8 0.9 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1682 PF07946.14 ORX93092.1 - 3e-92 309.3 5.8 3.5e-92 309.1 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) F_actin_bind PF08919.10 ORX93092.1 - 0.0016 18.5 3.3 0.096 12.8 0.4 2.4 2 0 0 2 2 2 2 F-actin binding Silic_transp PF03842.13 ORX93092.1 - 3 6.0 4.5 4.3 5.5 4.5 1.2 1 0 0 1 1 1 0 Silicon transporter THOC7 PF05615.13 ORX93093.1 - 6.3e-29 100.9 8.6 6.3e-29 100.9 8.6 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 COMM_domain PF07258.14 ORX93093.1 - 0.047 13.8 3.8 0.88 9.7 0.4 2.5 2 0 0 2 2 2 0 COMM domain Vps23_core PF09454.10 ORX93093.1 - 0.057 13.4 0.9 0.55 10.2 0.3 2.5 2 0 0 2 2 2 0 Vps23 core domain DUF4407 PF14362.6 ORX93093.1 - 0.7 9.2 7.6 0.91 8.8 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YnfE PF17452.2 ORX93093.1 - 0.81 10.0 4.6 1.4 9.3 1.5 2.8 2 1 0 2 2 2 0 Uncharacterized YnfE-like DUF4094 PF13334.6 ORX93093.1 - 1 9.8 6.3 0.65 10.4 1.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF1542 PF07564.11 ORX93093.1 - 1.4 9.1 9.6 3.3 7.9 5.8 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) PRKG1_interact PF15898.5 ORX93093.1 - 4.3 8.3 15.0 1.6 9.6 6.7 3.5 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Efg1 PF10153.9 ORX93093.1 - 5.1 7.5 9.3 2.2 8.7 4.3 2.4 1 1 1 2 2 2 0 rRNA-processing protein Efg1 Polyketide_cyc PF03364.20 ORX93094.1 - 2.9e-25 89.0 0.0 3.4e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Herpes_gE PF02480.16 ORX93095.1 - 0.00098 18.0 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 ORX93095.1 - 0.0021 18.9 0.0 0.0034 18.2 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 ORX93095.1 - 0.0068 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 ORX93095.1 - 0.012 15.9 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.11 ORX93095.1 - 0.036 13.5 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM132D_C PF15706.5 ORX93095.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TRP PF06011.12 ORX93095.1 - 0.083 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF2062 PF09835.9 ORX93095.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Rhabdo_glycop PF00974.18 ORX93095.1 - 0.11 10.9 0.3 0.14 10.6 0.3 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TMEM154 PF15102.6 ORX93095.1 - 0.19 11.7 0.4 0.38 10.7 0.4 1.6 1 1 0 1 1 1 0 TMEM154 protein family FAM176 PF14851.6 ORX93095.1 - 0.2 11.3 1.9 0.31 10.7 1.2 1.7 2 1 0 2 2 2 0 FAM176 family Insulin_TMD PF17870.1 ORX93095.1 - 0.2 11.7 1.2 0.37 10.9 1.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 ORX93095.1 - 0.62 10.0 2.5 1.3 9.0 2.5 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 ORX93095.1 - 5.7 6.4 12.0 11 5.5 12.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-U1 PF06220.12 ORX93096.1 - 7.8e-06 25.6 1.4 1.7e-05 24.5 1.4 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-CCCH PF00642.24 ORX93096.1 - 1e-05 25.3 2.1 1e-05 25.3 2.1 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX93096.1 - 2.9e-05 23.7 2.1 6.5e-05 22.6 2.1 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX93096.1 - 0.00025 21.0 2.4 0.0005 20.0 2.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 ORX93096.1 - 0.0092 16.4 1.0 0.0092 16.4 1.0 2.0 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-DBF PF07535.12 ORX93096.1 - 0.028 14.5 0.9 0.062 13.4 0.9 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_jaz PF12171.8 ORX93096.1 - 0.16 12.3 7.1 1.2 9.5 7.1 2.4 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORX93097.1 - 6.8e-13 48.3 14.4 8.7e-08 32.2 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93097.1 - 3.8e-07 30.4 11.4 0.00012 22.7 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX93097.1 - 1.2e-05 25.5 4.7 1.2e-05 25.5 4.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX93097.1 - 2.4e-05 24.2 0.2 2.4e-05 24.2 0.2 3.2 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORX93097.1 - 0.00022 21.4 1.1 0.33 11.1 0.2 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger FOXP-CC PF16159.5 ORX93097.1 - 0.0024 18.5 2.8 0.17 12.6 0.1 2.1 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORX93097.1 - 0.0032 17.8 3.6 0.25 11.8 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX93097.1 - 0.0046 17.2 0.5 0.011 16.0 0.5 1.6 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-LYAR PF08790.11 ORX93097.1 - 0.016 15.1 1.3 0.25 11.3 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger CHORD PF04968.12 ORX93097.1 - 0.016 15.9 3.2 0.97 10.2 0.2 2.1 1 1 1 2 2 2 0 CHORD Ogr_Delta PF04606.12 ORX93097.1 - 0.021 14.8 0.2 2.4 8.2 0.1 2.2 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 ORX93097.1 - 0.052 13.8 5.1 0.073 13.4 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CCAP PF11105.8 ORX93097.1 - 0.13 12.3 0.4 0.13 12.3 0.4 1.1 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a O-FucT PF10250.9 ORX93098.1 - 1.4e-13 51.3 0.0 1.6e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RF-1 PF00472.20 ORX93099.1 - 5e-17 61.9 0.0 5.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain JAB PF01398.21 ORX93100.1 - 5.8e-13 48.9 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.31 ORX93100.1 - 6.5e-11 42.2 0.1 1.2e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.6 ORX93100.1 - 2.2e-07 30.7 0.1 4.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 ORX93100.1 - 0.002 18.3 1.2 0.0069 16.6 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Metallophos PF00149.28 ORX93101.1 - 0.00014 22.5 2.1 0.00041 20.9 2.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Colicin_Pyocin PF01320.18 ORX93101.1 - 0.097 12.8 1.1 0.27 11.4 0.0 2.3 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein Na_sulph_symp PF00939.19 ORX93102.1 - 1.7e-36 126.3 32.9 2.3e-36 125.9 32.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 ORX93102.1 - 4.8e-34 118.9 13.6 4.8e-23 82.7 7.9 2.7 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 ORX93102.1 - 3.1e-24 85.7 40.8 8.9e-17 61.2 21.4 2.3 1 1 1 2 2 2 2 Citrate transporter GATA PF00320.27 ORX93104.1 - 4.9e-18 64.4 5.6 7.1e-18 63.9 5.6 1.3 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 ORX93104.1 - 0.017 15.2 0.7 0.031 14.4 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 ORX93104.1 - 0.026 14.7 0.3 0.033 14.3 0.3 1.2 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_9 PF14369.6 ORX93104.1 - 0.064 13.5 1.3 0.14 12.4 1.3 1.5 1 0 0 1 1 1 0 zinc-ribbon MIS13 PF08202.11 ORX93105.1 - 1.5e-39 136.1 11.1 1.5e-39 136.1 11.1 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family HisK_sensor PF18698.1 ORX93105.1 - 0.039 14.3 1.9 0.039 14.3 1.9 2.2 2 0 0 2 2 2 0 Histidine kinase sensor domain Promethin PF16015.5 ORX93109.1 - 5.5e-07 29.5 7.3 7.9e-07 29.0 7.3 1.2 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 ORX93109.1 - 0.024 13.4 0.2 0.031 13.0 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.11 ORX93109.1 - 0.042 13.4 5.0 0.061 12.9 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Peptidase_U4 PF03419.13 ORX93109.1 - 5.7 6.1 8.5 8 5.6 8.5 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA G-alpha PF00503.20 ORX93110.1 - 2.1e-114 382.4 0.1 2.5e-114 382.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX93110.1 - 1.4e-13 50.7 0.4 6.4e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX93110.1 - 0.00026 20.4 0.4 0.023 14.0 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region KH_10 PF17905.1 ORX93110.1 - 0.044 14.2 0.2 15 6.1 0.0 2.9 3 0 0 3 3 3 0 GLD-3 KH domain 5 AAA_29 PF13555.6 ORX93110.1 - 0.052 13.3 0.1 0.17 11.6 0.1 1.8 1 1 1 2 2 2 0 P-loop containing region of AAA domain KIND PF16474.5 ORX93110.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain FtsK_SpoIIIE PF01580.18 ORX93110.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 ORX93110.1 - 0.16 12.2 1.2 8.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Tyrosinase PF00264.20 ORX93111.1 - 5.7e-35 121.6 8.6 3.5e-34 119.0 6.5 2.4 2 1 0 2 2 2 1 Common central domain of tyrosinase AvrRpt-cleavage PF05627.11 ORX93111.1 - 1.1 8.6 3.9 17 4.9 0.1 2.8 3 0 0 3 3 3 0 Cleavage site for pathogenic type III effector avirulence factor Avr Cytochrom_C PF00034.21 ORX93112.1 - 1.3e-07 32.7 0.0 2.1e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORX93112.1 - 3.9e-05 23.9 0.5 6.7e-05 23.1 0.5 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III ParA PF10609.9 ORX93113.1 - 2.4e-99 331.8 0.0 2.8e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORX93113.1 - 5.6e-10 39.4 0.0 4e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 ORX93113.1 - 3.4e-06 26.5 0.3 0.00015 21.0 0.1 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 ORX93113.1 - 1.4e-05 25.1 0.0 0.00011 22.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORX93113.1 - 0.0002 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 ORX93113.1 - 0.0029 16.9 0.0 0.012 14.9 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 ORX93113.1 - 0.0042 16.1 0.1 0.0063 15.5 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 ORX93113.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Fer4_NifH PF00142.18 ORX93113.1 - 0.0085 15.6 0.0 0.72 9.2 0.0 2.6 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PcrB PF01884.17 ORX93113.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 PcrB family NB-ARC PF00931.22 ORX93113.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 ORX93113.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CBP_BcsQ PF06564.12 ORX93113.1 - 0.02 14.4 0.0 0.11 11.9 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 ORX93113.1 - 0.15 11.9 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain CitMHS PF03600.16 ORX93114.1 - 2.3e-14 53.3 0.0 4.5e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Citrate transporter FAD_binding_2 PF00890.24 ORX93115.1 - 2.1e-127 425.7 3.3 2.7e-127 425.3 3.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORX93115.1 - 1e-45 154.8 2.7 1.6e-45 154.2 2.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 ORX93115.1 - 3.2e-05 23.3 0.3 0.017 14.3 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 ORX93115.1 - 4e-05 23.0 0.3 0.00098 18.4 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX93115.1 - 0.00025 20.2 5.7 0.024 13.7 2.5 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORX93115.1 - 0.00073 18.7 0.4 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORX93115.1 - 0.0038 16.5 0.2 0.0068 15.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX93115.1 - 0.029 14.0 1.0 0.049 13.2 1.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX93115.1 - 0.12 11.1 2.2 0.36 9.5 0.8 2.5 4 0 0 4 4 4 0 HI0933-like protein Hus1 PF04005.12 ORX93116.1 - 2.7e-78 263.0 0.3 3e-78 262.9 0.3 1.0 1 0 0 1 1 1 1 Hus1-like protein PNK3P PF08645.11 ORX93117.1 - 3.4e-56 189.4 0.0 7.9e-56 188.2 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ORX93117.1 - 3e-19 69.6 0.0 2e-16 60.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORX93117.1 - 0.00011 21.6 0.0 0.0017 17.7 0.0 2.6 2 1 1 3 3 3 1 Zeta toxin KTI12 PF08433.10 ORX93117.1 - 0.00013 21.5 1.5 0.013 15.0 1.5 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Hydrolase_6 PF13344.6 ORX93117.1 - 0.016 15.3 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Phage_H_T_join PF05521.11 ORX93117.1 - 0.14 12.7 0.1 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Phage head-tail joining protein adh_short PF00106.25 ORX93118.1 - 1.4e-57 194.3 0.5 1.7e-57 194.1 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93118.1 - 6e-50 170.0 0.1 1.3e-49 168.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93118.1 - 2.6e-14 53.5 0.3 3.2e-14 53.2 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX93118.1 - 0.001 19.0 0.5 0.0012 18.8 0.5 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX93118.1 - 0.0022 17.5 0.1 0.0037 16.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ORX93118.1 - 0.0026 17.1 0.2 0.0087 15.4 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.23 ORX93118.1 - 0.0057 16.6 0.0 0.0092 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORX93118.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 ORX93118.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 ORX93118.1 - 0.026 14.1 0.3 0.038 13.5 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 ORX93118.1 - 0.056 13.3 0.2 0.11 12.3 0.2 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC_tran PF00005.27 ORX93119.1 - 1.2e-57 194.2 0.0 5.5e-28 98.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ORX93119.1 - 1.6e-47 162.3 43.7 8.1e-26 90.9 22.8 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORX93119.1 - 5.4e-20 72.4 0.1 1.8e-06 28.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 ORX93119.1 - 0.00016 21.7 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 ORX93119.1 - 0.00057 19.7 0.1 2.6 7.6 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 ORX93119.1 - 0.0033 16.9 0.0 4 6.8 0.0 3.4 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX93119.1 - 0.0037 17.8 1.3 1.9 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX93119.1 - 0.0041 17.0 0.3 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Mg_chelatase PF01078.21 ORX93119.1 - 0.0048 16.3 0.0 7.2 5.9 0.0 3.3 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORX93119.1 - 0.022 14.5 2.1 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bromo_coat PF01318.18 ORX93119.1 - 0.052 13.6 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Bromovirus coat protein SbcCD_C PF13558.6 ORX93119.1 - 0.13 12.5 0.0 1.9 8.8 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 ORX93119.1 - 0.17 12.3 0.1 15 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 ORX93119.1 - 0.31 10.7 1.9 12 5.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CCB1 PF12046.8 ORX93119.1 - 0.62 9.4 3.9 24 4.2 0.0 2.7 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Methyltransf_25 PF13649.6 ORX93120.1 - 2.4e-14 53.8 0.0 3.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX93120.1 - 9.6e-14 51.3 0.0 3.7e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ORX93120.1 - 2.7e-13 50.4 0.0 3.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX93120.1 - 1.5e-08 34.6 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX93120.1 - 1.1e-06 29.3 0.0 1.7e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX93120.1 - 2.8e-06 27.3 0.0 3.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX93120.1 - 0.002 17.7 0.0 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain GDP_Man_Dehyd PF16363.5 ORX93133.1 - 6.5e-35 121.1 0.2 7.3e-35 120.9 0.2 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TAA-Trp-ring PF15401.6 ORX93133.1 - 0.015 15.7 0.3 0.064 13.7 0.0 2.0 1 1 1 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Iso_dh PF00180.20 ORX93135.1 - 5.4e-102 341.5 0.1 6.3e-102 341.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MgtE PF01769.16 ORX93136.1 - 9.8e-42 142.3 33.0 2.7e-22 79.5 5.4 3.3 3 0 0 3 3 3 2 Divalent cation transporter GYF PF02213.16 ORX93137.1 - 3.8e-18 64.9 0.2 8.3e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 ORX93137.1 - 0.00021 21.0 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 1 GYF domain 2 F_actin_cap_B PF01115.17 ORX93138.1 - 1.9e-107 358.3 0.0 2.3e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit adh_short PF00106.25 ORX93139.1 - 8.6e-57 191.7 0.5 1.3e-56 191.1 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93139.1 - 1e-42 146.3 0.3 1.3e-42 146.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93139.1 - 1.7e-16 60.6 0.1 2.1e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX93139.1 - 2.8e-06 27.4 0.2 5.1e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORX93139.1 - 9.3e-05 21.7 0.3 0.00015 21.0 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORX93139.1 - 9.9e-05 21.9 0.1 0.00016 21.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX93139.1 - 0.00096 18.6 0.0 0.0029 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 ORX93139.1 - 0.042 13.2 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ORX93139.1 - 0.056 13.5 0.1 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF148 PF02520.17 ORX93139.1 - 0.077 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Helicase_RecD PF05127.14 ORX93139.1 - 0.09 12.6 0.1 0.24 11.2 0.1 1.7 1 1 0 1 1 1 0 Helicase adh_short PF00106.25 ORX93140.1 - 3.9e-60 202.6 0.7 5.1e-60 202.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93140.1 - 7.7e-47 159.8 0.4 9.8e-47 159.5 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93140.1 - 2.3e-16 60.3 0.2 2.7e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX93140.1 - 5.7e-07 29.0 0.6 9.4e-07 28.2 0.6 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ORX93140.1 - 3.5e-06 27.0 0.3 5.3e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX93140.1 - 4.3e-06 26.4 0.1 1e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX93140.1 - 0.0013 18.2 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 ORX93140.1 - 0.003 17.0 0.0 0.008 15.6 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Helicase_RecD PF05127.14 ORX93140.1 - 0.014 15.3 0.1 0.1 12.4 0.1 2.1 2 1 0 2 2 2 0 Helicase Shikimate_DH PF01488.20 ORX93140.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 ORX93140.1 - 0.024 14.0 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 ORX93140.1 - 0.036 14.5 0.1 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORX93140.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.13 ORX93140.1 - 0.13 12.2 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.25 ORX93141.1 - 2.9e-57 193.3 0.4 3.4e-57 193.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93141.1 - 1.5e-42 145.7 0.2 1.9e-42 145.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93141.1 - 2.7e-16 60.0 0.1 3.2e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX93141.1 - 5.2e-05 22.5 0.2 9.1e-05 21.7 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORX93141.1 - 8.2e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX93141.1 - 0.0046 16.4 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 ORX93141.1 - 0.044 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF148 PF02520.17 ORX93141.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Shikimate_DH PF01488.20 ORX93141.1 - 0.07 13.2 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 ORX93142.1 - 1.5e-56 191.0 0.1 1.8e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93142.1 - 6.7e-40 137.1 0.0 8e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93142.1 - 1.3e-13 51.2 0.0 1.7e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORX93142.1 - 4.8e-05 22.6 0.1 6.9e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ORX93142.1 - 0.00072 19.5 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX93142.1 - 0.001 18.6 0.7 0.0031 17.0 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORX93142.1 - 0.019 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 ORX93142.1 - 0.036 13.5 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase dCMP_cyt_deam_2 PF08211.12 ORX93143.1 - 0.00028 21.1 0.2 0.032 14.4 0.0 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 ORX93143.1 - 0.00085 19.2 0.1 0.71 9.8 0.0 2.7 3 0 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region RNase_T PF00929.24 ORX93144.1 - 9.6e-08 32.7 0.0 1.8e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORX93144.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease GTP_EFTU PF00009.27 ORX93146.1 - 2.9e-57 193.3 0.8 3.3e-57 193.2 0.1 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX93146.1 - 5e-31 107.3 0.3 2.2e-30 105.2 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX93146.1 - 3.2e-17 62.7 3.0 7.8e-17 61.4 3.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX93146.1 - 7.1e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX93146.1 - 0.0079 16.1 0.0 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 ORX93146.1 - 0.0082 15.8 0.4 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ORX93146.1 - 0.032 14.0 0.3 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADK PF00406.22 ORX93147.1 - 1.7e-60 203.5 0.0 2.1e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORX93147.1 - 1.8e-23 83.5 0.1 9.3e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORX93147.1 - 4.3e-17 61.8 0.1 1.3e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORX93147.1 - 0.00049 20.6 0.0 0.0015 19.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX93147.1 - 0.00056 20.1 0.0 0.0011 19.1 0.0 1.4 2 0 0 2 2 2 1 AAA domain DUF3640 PF12342.8 ORX93147.1 - 0.043 13.5 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) AAA_24 PF13479.6 ORX93147.1 - 0.095 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ubiq_cyt_C_chap PF03981.12 ORX93148.1 - 1.2e-33 116.2 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HEPN_Swt1 PF18731.1 ORX93148.1 - 0.03 14.7 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Swt1-like HEPN NADH-u_ox-rdase PF10785.9 ORX93149.1 - 3.4e-30 104.6 0.2 5.3e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 ORX93149.1 - 3.5e-19 68.6 0.3 5.6e-19 67.9 0.3 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit TACC_C PF05010.14 ORX93149.1 - 0.034 13.9 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CDC50 PF03381.15 ORX93150.1 - 3.1e-98 328.7 0.1 3.7e-98 328.5 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Forkhead PF00250.18 ORX93151.1 - 1.6e-36 124.5 0.2 1.8e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 Forkhead domain Peptidase_S8 PF00082.22 ORX93152.1 - 1.1e-40 139.8 0.6 1.6e-40 139.3 0.6 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORX93152.1 - 7.8e-25 86.7 0.1 1.7e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORX93152.1 - 0.013 16.3 1.0 0.098 13.4 1.0 2.4 2 1 0 2 2 2 0 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORX93152.1 - 0.02 15.4 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family MCM PF00493.23 ORX93153.1 - 1.1e-101 338.6 0.0 1.9e-101 337.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORX93153.1 - 1.6e-33 115.3 0.8 2.8e-33 114.4 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORX93153.1 - 3.6e-21 75.4 0.0 9.3e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORX93153.1 - 6.6e-15 55.6 0.2 2.1e-14 54.0 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORX93153.1 - 2.4e-07 30.4 0.0 4.5e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORX93153.1 - 1.6e-06 28.2 0.0 8.5e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORX93153.1 - 0.001 18.9 0.2 0.0057 16.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ORX93153.1 - 0.01 15.7 0.2 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 ORX93153.1 - 0.047 13.4 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ZapD PF07072.11 ORX93153.1 - 0.048 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Cell division protein Mg_chelatase_C PF13335.6 ORX93153.1 - 0.071 13.8 0.2 0.66 10.7 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI C-terminal Zn-ribbon_8 PF09723.10 ORX93153.1 - 0.14 12.3 2.6 0.35 11.0 2.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain MCM PF00493.23 ORX93154.1 - 3.8e-100 333.6 0.0 6e-100 333.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORX93154.1 - 1.2e-36 125.3 0.0 2.2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORX93154.1 - 1.6e-25 89.3 0.1 4.5e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 ORX93154.1 - 3e-20 73.0 16.0 3e-20 73.0 16.0 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 ORX93154.1 - 6.8e-13 49.1 0.0 2.2e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORX93154.1 - 4e-09 36.2 0.0 2.9e-07 30.1 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORX93154.1 - 2.4e-06 27.6 0.0 8.5e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORX93154.1 - 5.8e-06 26.2 0.1 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORX93154.1 - 0.002 17.8 0.1 0.012 15.3 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 ORX93154.1 - 0.069 13.6 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ORX93154.1 - 0.11 12.2 0.1 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 ORX93154.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2400 PF09674.10 ORX93154.1 - 0.17 11.8 1.6 1.9 8.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) RNA_POL_M_15KD PF02150.16 ORX93154.1 - 0.48 10.3 1.9 0.98 9.3 1.9 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit LUC7 PF03194.15 ORX93155.1 - 5.5e-29 101.6 1.7 9.8e-29 100.8 1.7 1.4 1 1 0 1 1 1 1 LUC7 N_terminus Parathyroid PF01279.17 ORX93155.1 - 0.015 15.9 2.4 0.015 15.9 2.4 1.8 2 0 0 2 2 2 0 Parathyroid hormone family HERV-K_env_2 PF13804.6 ORX93155.1 - 0.2 11.4 0.3 0.36 10.6 0.3 1.4 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein JmjC PF02373.22 ORX93156.1 - 1.2e-43 148.1 1.9 1.3e-42 144.8 0.7 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 ORX93156.1 - 1.3e-21 77.1 0.0 2.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 ORX93156.1 - 6e-19 67.7 5.2 2.7e-18 65.6 2.9 2.8 3 0 0 3 3 3 1 jmjN domain zf-C5HC2 PF02928.16 ORX93156.1 - 2e-12 47.3 8.9 2e-12 47.3 8.9 2.9 2 1 1 3 3 3 1 C5HC2 zinc finger PHD PF00628.29 ORX93156.1 - 1.3e-08 34.6 12.3 1.3e-08 34.6 12.3 2.4 2 1 1 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 ORX93156.1 - 0.028 14.6 1.9 0.028 14.6 1.9 2.6 2 0 0 2 2 2 0 PHD-zinc-finger like domain Zf_RING PF16744.5 ORX93156.1 - 2.2 8.5 15.4 0.097 12.8 5.1 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger NpwBP PF12622.7 ORX93157.1 - 0.03 15.1 0.2 0.12 13.2 0.2 2.0 1 0 0 1 1 1 0 mRNA biogenesis factor Tim54 PF11711.8 ORX93158.1 - 1.8e-54 185.0 0.3 1.5e-52 178.6 0.4 2.1 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Ribosomal_L22e PF01776.17 ORX93159.1 - 1.4e-49 167.0 2.3 1.8e-49 166.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family T4_Gp59_N PF08993.10 ORX93159.1 - 0.057 13.8 2.1 0.44 11.0 0.4 2.1 1 1 1 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase PPR_2 PF13041.6 ORX93160.1 - 1.3e-48 162.9 8.6 8.1e-13 48.4 0.0 9.3 3 1 8 11 11 11 8 PPR repeat family PPR_3 PF13812.6 ORX93160.1 - 2.3e-36 123.7 3.7 3.2e-09 36.7 0.0 5.7 4 1 1 6 6 5 4 Pentatricopeptide repeat domain PPR PF01535.20 ORX93160.1 - 1.3e-30 103.4 7.5 4.6e-05 23.4 0.0 9.7 10 0 0 10 10 10 6 PPR repeat PPR_1 PF12854.7 ORX93160.1 - 1.8e-26 91.5 5.9 1.9e-06 27.5 0.0 8.7 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 ORX93160.1 - 8.2e-20 71.1 0.1 9.6e-07 28.4 0.0 4.2 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 ORX93160.1 - 8.4e-09 35.3 2.6 0.00056 19.7 0.0 4.9 3 2 3 6 6 6 2 Mitochondrial ATPase expression TPR_19 PF14559.6 ORX93160.1 - 3.8e-05 24.1 0.1 1.1 9.8 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX93160.1 - 0.0014 18.7 0.5 9.1 6.8 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX93160.1 - 0.0016 19.1 0.0 3.2 8.8 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat RPM2 PF08579.11 ORX93160.1 - 0.004 17.6 2.3 15 6.0 0.1 4.4 2 2 2 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_2 PF07719.17 ORX93160.1 - 0.017 15.2 0.6 52 4.3 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX93160.1 - 0.035 13.0 3.7 5.9 5.6 0.0 3.5 1 1 3 4 4 4 0 Mitochondrial 28S ribosomal protein S27 Drf_FH3 PF06367.16 ORX93160.1 - 0.052 13.2 0.1 1.8 8.1 0.0 2.5 1 1 1 2 2 2 0 Diaphanous FH3 Domain TPR_1 PF00515.28 ORX93160.1 - 0.06 13.2 0.1 13 5.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BKACE PF05853.12 ORX93160.1 - 0.19 11.0 0.0 30 3.8 0.0 2.8 2 1 1 3 3 3 0 beta-keto acid cleavage enzyme Clathrin PF00637.20 ORX93160.1 - 1.3 8.9 5.4 4 7.3 0.2 3.9 3 2 2 5 5 5 0 Region in Clathrin and VPS Peptidase_S8 PF00082.22 ORX93161.1 - 2.3e-38 132.2 0.3 3.3e-38 131.6 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORX93161.1 - 3.8e-17 62.1 0.1 9e-17 60.9 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Chitin_synth_2 PF03142.15 ORX93162.1 - 9.5e-124 413.9 0.8 1e-82 278.5 0.2 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX93162.1 - 1.6e-11 44.5 5.1 1.6e-11 44.5 5.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX93162.1 - 2.1e-11 44.2 0.0 3.4e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX93162.1 - 0.00022 21.1 0.1 0.29 10.9 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX93162.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Sulfate_transp PF00916.20 ORX93163.1 - 5.1e-100 334.9 22.4 6.4e-100 334.6 22.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX93163.1 - 7.5e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF2104 PF09877.9 ORX93163.1 - 0.00051 20.3 0.4 0.00051 20.3 0.4 2.6 3 0 0 3 3 3 1 Predicted membrane protein (DUF2104) STAS_2 PF13466.6 ORX93163.1 - 0.04 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 STAS domain NAP PF00956.18 ORX93163.1 - 0.25 10.5 0.0 3.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Sulfate_transp PF00916.20 ORX93164.1 - 2.8e-100 335.7 22.4 3.4e-100 335.5 22.4 1.1 1 0 0 1 1 1 1 Sulfate permease family DUF2104 PF09877.9 ORX93164.1 - 0.00039 20.6 0.4 0.00039 20.6 0.4 2.8 3 0 0 3 3 3 1 Predicted membrane protein (DUF2104) STAS PF01740.21 ORX93164.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 STAS domain Ribosomal_L34e PF01199.18 ORX93165.1 - 1.9e-46 156.3 4.1 2.2e-46 156.1 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e TFIIA PF03153.13 ORX93166.1 - 2.1e-63 215.7 29.9 2.9e-44 152.7 24.5 2.5 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 ORX93166.1 - 0.17 11.4 7.9 0.23 11.0 7.9 1.3 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 ORX93166.1 - 0.47 8.5 12.6 0.62 8.1 12.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 ORX93166.1 - 0.48 10.1 7.3 0.74 9.5 7.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 ORX93166.1 - 1.6 8.0 10.0 2.6 7.3 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein Glypican PF01153.19 ORX93166.1 - 6.9 5.4 5.4 12 4.5 5.4 1.4 1 1 0 1 1 1 0 Glypican OB_NTP_bind PF07717.16 ORX93167.1 - 2.9e-20 72.4 0.0 8.3e-20 71.0 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ORX93167.1 - 1.5e-18 67.0 0.0 3.8e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORX93167.1 - 4.5e-14 52.7 0.0 1.4e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORX93167.1 - 5.7e-07 29.5 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORX93167.1 - 1.2e-05 25.6 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX93167.1 - 0.0022 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORX93167.1 - 0.0035 16.5 0.0 0.0084 15.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 ORX93167.1 - 0.0038 17.8 0.1 0.15 12.6 0.1 2.7 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.6 ORX93167.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORX93167.1 - 0.015 15.3 0.4 1.1 9.3 0.4 2.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX93167.1 - 0.09 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORX93167.1 - 0.12 11.7 0.3 0.5 9.6 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin SRP54 PF00448.22 ORX93167.1 - 0.18 11.4 0.6 0.42 10.2 0.1 1.9 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 ORX93167.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Aminotran_5 PF00266.19 ORX93168.1 - 5.9e-34 117.6 0.0 7.7e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 ORX93168.1 - 0.00072 19.6 0.2 0.18 11.9 0.0 2.5 2 1 0 2 2 2 2 B12 binding domain Cys_Met_Meta_PP PF01053.20 ORX93168.1 - 0.0015 17.2 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TPR_2 PF07719.17 ORX93170.1 - 2.7e-10 39.5 0.8 0.06 13.5 2.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX93170.1 - 1.5e-09 37.2 10.9 0.092 12.6 3.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX93170.1 - 7.4e-07 28.9 10.6 0.073 13.3 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX93170.1 - 6.2e-05 23.2 6.4 0.5 10.7 0.1 4.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX93170.1 - 0.00025 20.9 1.3 5.7 7.2 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX93170.1 - 0.0029 18.3 0.0 0.49 11.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX93170.1 - 0.012 15.4 0.8 15 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2385 PF09539.10 ORX93170.1 - 0.056 14.0 0.1 2.7 8.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) TPR_19 PF14559.6 ORX93170.1 - 0.12 12.9 0.1 2.3 8.8 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX93170.1 - 0.24 11.7 2.7 3.3 8.0 1.3 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORX93170.1 - 2.7 8.8 8.4 13 6.6 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Band_7 PF01145.25 ORX93171.1 - 7.9e-23 81.4 3.3 1.1e-22 80.9 3.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_L18 PF17135.4 ORX93172.1 - 1.1e-94 315.1 3.5 1.2e-94 314.9 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORX93172.1 - 0.028 15.1 0.1 0.028 15.1 0.1 2.1 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NFACT-R_1 PF05670.13 ORX93174.1 - 2.1e-34 118.4 0.0 7.7e-34 116.6 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 ORX93174.1 - 1.2e-32 112.0 0.0 1.2e-32 112.0 0.0 3.3 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 ORX93174.1 - 4.8e-26 91.5 5.1 4.8e-26 91.5 5.1 1.9 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_2 PF18297.1 ORX93174.1 - 0.015 15.5 0.0 1 9.6 0.0 3.2 2 0 0 2 2 2 0 NFACT protein RNA binding domain Flavokinase PF01687.17 ORX93175.1 - 3.3e-37 127.2 0.0 4.1e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Cyclin PF08613.11 ORX93185.1 - 1e-15 58.5 0.0 1.3e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX93185.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Methyltransf_2 PF00891.18 ORX93186.1 - 5.3e-42 143.5 0.0 9.2e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 ORX93186.1 - 1.2e-06 28.3 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 ORX93186.1 - 0.00013 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 ORX93186.1 - 0.00024 21.0 0.1 0.25 11.2 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93186.1 - 0.0014 19.3 0.0 0.0038 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX93186.1 - 0.0042 17.7 0.0 0.02 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 ORX93186.1 - 0.04 14.0 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 ORX93186.1 - 0.046 14.5 0.0 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 ORX93186.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain EXS PF03124.14 ORX93187.1 - 4.7e-95 318.7 22.0 5.5e-95 318.5 22.0 1.0 1 0 0 1 1 1 1 EXS family SelK_SelG PF10961.8 ORX93187.1 - 3 8.5 5.1 57 4.4 0.0 2.9 2 0 0 2 2 2 0 Selenoprotein SelK_SelG YibE_F PF07907.11 ORX93187.1 - 4 6.9 12.6 0.28 10.7 7.2 1.7 2 0 0 2 2 2 0 YibE/F-like protein YbhQ PF11076.8 ORX93188.1 - 1.3 9.0 8.0 0.58 10.2 4.6 2.0 2 1 0 2 2 2 0 Putative inner membrane protein YbhQ Chitin_synth_2 PF03142.15 ORX93190.1 - 2.2e-281 934.0 0.1 3.1e-281 933.6 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX93190.1 - 2.9e-14 53.5 0.0 9.5e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX93190.1 - 4.1e-12 46.4 7.6 2.1e-11 44.1 7.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX93190.1 - 0.00042 19.8 0.1 0.028 13.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX93190.1 - 0.0045 16.8 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF4229 PF14012.6 ORX93190.1 - 2.8 8.1 10.6 23 5.2 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) RhoGEF PF00621.20 ORX93191.1 - 1.4e-41 142.7 2.9 1.4e-41 142.7 2.9 1.7 2 0 0 2 2 2 1 RhoGEF domain Lipase_3 PF01764.25 ORX93192.1 - 1.2e-28 99.7 0.0 1.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 ORX93192.1 - 0.028 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 ORX93192.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX93192.1 - 0.13 12.9 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family GILT PF03227.16 ORX93193.1 - 1.3e-18 67.2 2.4 2.6e-18 66.2 2.4 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_5 PF13743.6 ORX93193.1 - 0.036 13.7 0.0 2.6 7.7 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin AMP-binding PF00501.28 ORX93194.1 - 0 1884.0 0.0 1.9e-96 323.3 0.0 7.3 8 0 0 8 8 8 6 AMP-binding enzyme Condensation PF00668.20 ORX93194.1 - 0 1444.1 18.4 1.3e-53 182.3 0.0 11.2 11 0 0 11 11 11 10 Condensation domain PP-binding PF00550.25 ORX93194.1 - 5.5e-80 263.7 1.7 1.5e-13 50.8 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site Thioesterase PF00975.20 ORX93194.1 - 6.2e-26 91.9 0.1 1.8e-25 90.4 0.1 1.8 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 ORX93194.1 - 2.4e-25 89.3 0.0 0.00085 20.3 0.0 6.9 6 1 0 6 6 6 5 AMP-binding enzyme C-terminal domain DUF5122 PF17164.4 ORX93194.1 - 0.002 18.4 22.9 12 6.2 0.2 6.4 6 0 0 6 6 6 5 Domain of unknown function (DUF5122) beta-propeller Mig-14 PF07395.11 ORX93194.1 - 0.0023 17.4 0.1 3.4 7.0 0.0 2.8 3 0 0 3 3 3 2 Mig-14 TetR_C_12 PF16914.5 ORX93194.1 - 0.076 13.1 0.3 52 4.0 0.0 3.8 4 0 0 4 4 4 0 Bacterial transcriptional repressor C-terminal MRF_C1 PF13887.6 ORX93194.1 - 0.15 11.2 0.0 28 4.0 0.0 2.9 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 THP2 PF09432.10 ORX93194.1 - 3.6 7.7 6.5 21 5.1 0.1 4.9 7 0 0 7 7 7 0 Tho complex subunit THP2 DUF1179 PF06678.11 ORX93194.1 - 3.8 7.5 10.5 0.34 10.9 0.0 5.0 8 0 0 8 8 8 0 Protein of unknown function (DUF1179) ZT_dimer PF16916.5 ORX93195.1 - 9.9e-13 48.0 0.1 1.2e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Carn_acyltransf PF00755.20 ORX93196.1 - 2.3e-07 29.8 1.7 0.41 9.2 0.0 3.1 3 0 0 3 3 3 3 Choline/Carnitine o-acyltransferase FBD PF08387.10 ORX93196.1 - 7.1e-05 22.6 0.0 28 4.7 0.0 4.7 4 0 0 4 4 4 0 FBD FeoB_C PF07664.12 ORX93196.1 - 0.0032 17.1 8.6 3 7.6 0.1 4.6 6 0 0 6 6 6 2 Ferrous iron transport protein B C terminus DUF2121 PF09894.9 ORX93196.1 - 0.0048 16.5 0.0 19 4.7 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2121) DUF4416 PF14385.6 ORX93196.1 - 0.0055 16.6 0.0 16 5.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4416) DUF305 PF03713.13 ORX93196.1 - 0.012 15.8 0.0 50 4.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF305) DUF3723 PF12520.8 ORX93196.1 - 0.024 13.3 0.3 25 3.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3723) NOD PF06816.13 ORX93196.1 - 0.091 12.4 0.4 86 2.9 0.0 3.5 3 0 0 3 3 3 0 NOTCH protein NR_Repeat PF14046.6 ORX93196.1 - 0.48 10.6 3.0 73 3.6 0.0 3.9 4 0 0 4 4 4 0 Nuclear receptor repeat YqzE PF14038.6 ORX93196.1 - 2.6 8.1 13.8 52 3.9 0.1 4.3 4 0 0 4 4 4 0 YqzE-like protein HERV-K_REC PF15695.5 ORX93196.1 - 4.7 7.3 6.5 1.2e+02 2.9 0.2 3.5 3 0 0 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 CCDC-167 PF15188.6 ORX93197.1 - 0.0046 17.3 1.3 0.012 16.0 1.3 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 ArfGap PF01412.18 ORX93197.1 - 0.12 12.4 3.1 0.37 10.9 2.8 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Med9 PF07544.13 ORX93197.1 - 0.21 11.7 4.6 0.67 10.1 1.0 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 ORX93197.1 - 0.31 11.2 3.1 0.73 10.0 2.1 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 ORX93197.1 - 2.2 8.6 12.0 0.21 11.9 3.0 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 ORX93197.1 - 6.6 6.9 11.1 12 6.1 7.5 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Lig_chan PF00060.26 ORX93198.1 - 0.14 12.0 0.4 0.17 11.7 0.4 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel FXR_C1 PF16096.5 ORX93199.1 - 1.3 9.3 11.8 4.5 7.6 6.3 2.2 1 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Sel1 PF08238.12 ORX93207.1 - 1.8e-20 72.9 6.4 1.2e-06 28.9 1.1 4.2 4 0 0 4 4 4 4 Sel1 repeat FH2 PF02181.23 ORX93208.1 - 1.5e-96 323.8 2.4 1.5e-96 323.8 2.4 3.1 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORX93208.1 - 2.7e-28 98.8 5.5 2.7e-28 98.8 5.5 3.1 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORX93208.1 - 1.5e-26 93.2 0.3 1.5e-26 93.2 0.3 3.0 2 1 1 3 3 3 1 Diaphanous FH3 Domain RA PF00788.23 ORX93208.1 - 3.1e-06 27.7 0.0 0.0006 20.4 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 ORX93208.1 - 0.04 14.3 1.0 0.74 10.2 0.0 3.4 4 0 0 4 4 4 0 Ras-binding domain of Byr2 TMF_TATA_bd PF12325.8 ORX93208.1 - 2.5 8.3 32.6 0.42 10.8 0.2 5.9 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 ORX93208.1 - 3.4 7.9 14.2 7.8 6.8 0.7 5.3 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain RPW8 PF05659.11 ORX93208.1 - 4 7.1 7.5 3.4 7.4 0.5 3.7 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tup_N PF08581.10 ORX93208.1 - 8.8 6.7 9.1 1 9.7 0.5 3.6 3 0 0 3 3 3 0 Tup N-terminal Peroxidase_2 PF01328.17 ORX93209.1 - 5.7e-53 180.2 0.0 6.9e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Peptidase_M50 PF02163.22 ORX93210.1 - 9.2e-18 64.4 0.0 1.7e-15 57.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 MBOAT_2 PF13813.6 ORX93210.1 - 0.026 14.8 0.5 0.088 13.1 0.5 1.9 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Condensation PF00668.20 ORX93211.1 - 0 1504.3 0.3 1.3e-94 317.5 0.8 7.6 7 1 0 7 7 7 7 Condensation domain AMP-binding PF00501.28 ORX93211.1 - 0 1410.5 0.0 2e-96 323.2 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme AMP-binding_C PF13193.6 ORX93211.1 - 3.2e-39 133.8 0.1 1.7e-08 35.3 0.1 5.7 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX93211.1 - 5.2e-37 126.0 2.9 4.5e-08 33.3 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site ANAPC2 PF08672.11 ORX93211.1 - 0.0025 18.3 1.2 7.4 7.2 0.0 4.1 3 0 0 3 3 3 2 Anaphase promoting complex (APC) subunit 2 WES_acyltransf PF03007.16 ORX93211.1 - 0.016 15.0 0.0 8.4 6.1 0.0 3.4 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 ORX93212.1 - 8.1e-91 305.0 0.0 1.2e-90 304.4 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 ORX93212.1 - 1.6e-84 284.0 0.0 2.2e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 ORX93212.1 - 7.5e-25 88.4 0.0 1.5e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 ORX93212.1 - 7.6e-09 35.8 0.0 2.8e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX93212.1 - 1.7e-05 25.7 0.0 3.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 ORX93212.1 - 0.012 16.2 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX93212.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hanta_nucleocap PF00846.18 ORX93213.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Carn_acyltransf PF00755.20 ORX93213.1 - 0.12 11.0 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase YqzE PF14038.6 ORX93213.1 - 0.7 9.9 2.2 29 4.8 0.1 2.3 2 0 0 2 2 2 0 YqzE-like protein CCDC-167 PF15188.6 ORX93214.1 - 0.005 17.2 1.4 0.012 15.9 1.4 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 ArfGap PF01412.18 ORX93214.1 - 0.12 12.4 3.1 0.37 10.9 2.8 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Med9 PF07544.13 ORX93214.1 - 0.25 11.5 4.8 0.72 10.0 1.2 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 ORX93214.1 - 0.35 11.0 3.3 0.62 10.2 1.8 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 ORX93214.1 - 2.3 8.6 12.0 0.21 11.9 3.0 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 ORX93214.1 - 6.1 7.0 10.8 15 5.8 7.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Lig_chan PF00060.26 ORX93215.1 - 0.14 12.0 0.4 0.16 11.8 0.4 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel FXR_C1 PF16096.5 ORX93216.1 - 1.3 9.3 11.8 4.5 7.6 6.3 2.2 1 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Homeodomain PF00046.29 ORX93234.1 - 1e-16 60.5 4.2 1.1e-16 60.4 4.2 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX93234.1 - 0.00054 19.8 0.4 0.00079 19.3 0.1 1.5 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX93234.1 - 0.013 15.4 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 ORX93234.1 - 0.065 13.0 0.1 0.081 12.8 0.0 1.4 1 1 0 1 1 1 0 Homeodomain-like domain Homeodomain PF00046.29 ORX93235.1 - 1.6e-16 59.8 3.5 1.9e-16 59.6 3.5 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX93235.1 - 0.00079 19.3 0.7 0.0019 18.1 0.7 1.9 1 1 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 ORX93235.1 - 0.011 15.5 0.1 0.027 14.3 0.1 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Sec7 PF01369.20 ORX93236.1 - 2.7e-33 115.2 1.3 1.3e-32 113.0 0.2 2.2 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 ORX93236.1 - 2.4e-29 102.1 0.0 1.2e-28 99.9 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 ORX93236.1 - 4.5e-08 33.6 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Lzipper-MIP1 PF14389.6 ORX93236.1 - 0.0019 18.4 1.3 0.0068 16.7 1.3 2.0 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Cyclin PF08613.11 ORX93237.1 - 1e-07 32.5 0.0 1.4e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX93237.1 - 0.0003 20.5 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain STAG PF08514.11 ORX93238.1 - 7.1e-39 132.2 2.0 3.2e-38 130.1 2.0 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 ORX93238.1 - 0.00012 22.4 0.0 0.0057 17.0 0.0 3.4 2 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 ORX93238.1 - 0.00054 20.0 4.0 0.0097 16.0 0.1 4.3 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORX93238.1 - 0.0034 17.5 1.1 16 6.1 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cytidylate_kin2 PF13189.6 ORX93238.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 Cytidylate kinase-like family DUF4441 PF14536.6 ORX93238.1 - 0.14 12.4 2.3 1.2 9.4 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4441) Adaptin_binding PF10199.9 ORX93238.1 - 9.9 6.8 14.6 7e+02 0.8 0.0 3.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Histone_H2A_C PF16211.5 ORX93239.1 - 0.012 15.4 1.1 0.017 14.8 0.0 1.8 2 0 0 2 2 2 0 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 ORX93239.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 14-3-3 PF00244.20 ORX93240.1 - 2.2e-104 347.8 6.8 2.7e-104 347.5 6.8 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 ORX93240.1 - 0.022 14.8 0.2 0.051 13.6 0.2 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Complex1_LYR PF05347.15 ORX93241.1 - 3.8e-10 39.7 1.1 8.4e-10 38.6 1.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORX93241.1 - 2e-05 25.1 1.4 2.2e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Complex1_LYR-like DUF3500 PF12006.8 ORX93241.1 - 0.045 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Complex1_LYR_2 PF13233.6 ORX93241.1 - 0.18 12.6 3.2 0.49 11.2 3.2 2.0 1 1 0 1 1 1 0 Complex1_LYR-like UCH PF00443.29 ORX93242.1 - 5.4e-36 124.4 0.0 7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX93242.1 - 3.2e-07 30.3 1.5 8.3e-06 25.6 0.0 2.4 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HEAT_EZ PF13513.6 ORX93243.1 - 7.7e-28 96.5 15.4 6.8e-06 26.5 1.5 11.6 9 2 4 13 13 12 5 HEAT-like repeat HEAT PF02985.22 ORX93243.1 - 1.1e-24 84.4 14.2 3.7e-05 23.6 0.6 12.0 14 0 0 14 14 11 3 HEAT repeat HEAT_2 PF13646.6 ORX93243.1 - 6.4e-24 84.2 3.1 1.9e-07 31.4 0.2 8.6 5 3 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 ORX93243.1 - 4.6e-16 59.2 1.7 0.00012 22.6 0.0 7.8 7 1 1 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORX93243.1 - 2.8e-14 53.5 3.0 2.6e-06 27.6 0.1 5.8 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 ORX93243.1 - 4.5e-10 39.6 0.1 0.13 11.9 0.0 6.4 4 2 3 7 7 7 2 rRNA processing/ribosome biogenesis IBN_N PF03810.19 ORX93243.1 - 8.6e-09 35.2 0.9 3.8e-08 33.1 0.9 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain CLASP_N PF12348.8 ORX93243.1 - 2.3e-07 30.6 0.2 0.28 10.7 0.1 5.4 5 2 2 7 7 7 2 CLASP N terminal UME PF08064.13 ORX93243.1 - 2.8e-07 30.4 0.0 0.56 10.2 0.0 6.1 4 1 2 6 6 6 2 UME (NUC010) domain Adaptin_N PF01602.20 ORX93243.1 - 1.9e-06 26.8 2.5 0.1 11.2 0.1 4.3 4 1 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 ORX93243.1 - 2.2e-06 27.8 0.2 0.12 12.6 0.0 5.7 7 1 1 8 8 7 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 ORX93243.1 - 1.5e-05 24.3 4.2 0.032 13.4 0.0 5.2 4 3 2 6 6 6 2 RNAPII transcription regulator C-terminal Tti2 PF10521.9 ORX93243.1 - 0.00024 20.7 2.3 0.026 14.1 0.0 4.7 5 1 1 6 6 6 1 Tti2 family Arm PF00514.23 ORX93243.1 - 0.0021 18.0 3.8 6.5 6.9 0.1 6.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 ORX93243.1 - 0.0024 17.7 1.8 1.4 8.6 0.1 4.5 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 ORX93243.1 - 0.0042 17.0 9.2 4.8 7.1 0.0 7.7 6 4 3 10 10 10 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 ORX93243.1 - 0.0067 16.1 1.2 2.1 8.0 0.0 4.5 5 1 1 6 6 6 1 NUC173 domain TetR_C_27 PF17935.1 ORX93243.1 - 0.012 15.7 0.1 9.1 6.4 0.0 3.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TFCD_C PF12612.8 ORX93243.1 - 0.015 15.1 1.1 7.8 6.3 0.0 4.4 4 1 1 5 5 5 0 Tubulin folding cofactor D C terminal TAF6_C PF07571.13 ORX93243.1 - 0.019 15.3 0.1 1.7 9.1 0.1 3.4 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain SMK-1 PF04802.15 ORX93243.1 - 0.028 14.3 2.2 1.6 8.5 0.0 3.7 3 1 1 4 4 4 0 Component of IIS longevity pathway SMK-1 RICTOR_V PF14668.6 ORX93243.1 - 0.039 14.2 0.0 1.1 9.5 0.0 3.5 5 0 0 5 5 3 0 Rapamycin-insensitive companion of mTOR, domain 5 UNC45-central PF11701.8 ORX93243.1 - 0.16 11.9 4.1 25 4.8 0.0 5.2 4 2 2 6 6 6 0 Myosin-binding striated muscle assembly central Metallophos_2 PF12850.7 ORX93244.1 - 1e-18 68.1 0.0 1.4e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ORX93244.1 - 4.6e-06 27.3 1.1 0.039 14.5 0.0 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase ATG22 PF11700.8 ORX93246.1 - 3.7e-151 504.0 24.7 4.2e-151 503.8 24.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORX93246.1 - 7.6e-11 41.5 35.7 1.5e-07 30.7 24.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TssN PF17555.2 ORX93246.1 - 4.6e-05 22.9 7.7 4.6e-05 22.9 7.7 3.1 3 0 0 3 3 3 1 Type VI secretion system, TssN DUF2407_C PF13373.6 ORX93246.1 - 0.2 11.8 3.4 3.6 7.8 0.9 2.8 3 0 0 3 3 3 0 DUF2407 C-terminal domain SAP PF02037.27 ORX93247.1 - 1.8e-10 40.3 4.2 3.4e-10 39.4 4.2 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 ORX93247.1 - 2.3e-06 27.3 6.6 0.00089 19.0 0.5 3.4 3 0 0 3 3 3 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 ORX93247.1 - 0.049 13.4 0.7 0.11 12.2 0.7 1.6 1 1 0 1 1 1 0 HeH/LEM domain Phage_holin_6_1 PF09682.10 ORX93247.1 - 1.8 9.1 4.1 0.53 10.7 0.2 2.1 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) GFO_IDH_MocA PF01408.22 ORX93248.1 - 2.3e-08 34.9 0.0 3.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CTD_bind PF04818.13 ORX93249.1 - 3.8e-14 53.3 0.2 7.7e-14 52.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 ORX93249.1 - 1.4e-08 34.6 0.1 4.4e-08 33.0 0.1 1.9 1 0 0 1 1 1 1 Surp module zf-CCHC PF00098.23 ORX93249.1 - 5.4e-06 26.2 1.9 5.4e-06 26.2 1.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORX93249.1 - 0.0056 16.4 1.1 0.012 15.3 1.1 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RSRP PF17069.5 ORX93249.1 - 0.0063 16.1 71.0 0.0063 16.1 71.0 1.9 2 0 0 2 2 2 1 Arginine/Serine-Rich protein 1 AA_permease_N PF08403.10 ORX93249.1 - 0.035 13.6 0.5 0.18 11.3 0.5 2.2 1 0 0 1 1 1 0 Amino acid permease N-terminal G-patch PF01585.23 ORX93249.1 - 0.043 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 G-patch domain G-patch_2 PF12656.7 ORX93249.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 G-patch domain NifW PF03206.14 ORX93249.1 - 0.089 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW MOZ_SAS PF01853.18 ORX93250.1 - 2e-80 268.7 0.5 4e-80 267.7 0.1 1.7 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 ORX93250.1 - 1.2e-23 82.4 2.6 3.5e-23 81.0 2.6 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 ORX93250.1 - 2.3e-23 81.8 0.3 5.7e-23 80.6 0.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 ORX93250.1 - 0.004 17.5 0.0 0.009 16.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Chromo PF00385.24 ORX93250.1 - 0.075 13.0 0.2 0.24 11.3 0.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.25 ORX93250.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Agenet PF05641.12 ORX93250.1 - 0.15 12.6 0.1 0.32 11.5 0.1 1.6 1 0 0 1 1 1 0 Agenet domain Nup84_Nup100 PF04121.13 ORX93251.1 - 1.5e-185 618.4 8.3 1.7e-185 618.2 8.3 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PPARgamma_N PF12577.8 ORX93251.1 - 0.06 14.0 0.1 0.2 12.3 0.1 1.8 1 0 0 1 1 1 0 PPAR gamma N-terminal region EI24 PF07264.11 ORX93252.1 - 1.7e-17 64.2 7.2 2.3e-17 63.8 7.2 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF997 PF06196.12 ORX93252.1 - 2.4 8.2 8.0 6.9 6.8 8.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF997) 14-3-3 PF00244.20 ORX93254.1 - 1.2e-108 361.7 1.7 1.5e-108 361.4 1.7 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 ORX93254.1 - 0.66 10.5 0.1 0.66 10.5 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORX93255.1 - 3.4e-15 55.6 0.3 2.3e-07 30.5 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX93255.1 - 0.028 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 ORX93256.1 - 6.8e-09 35.4 1.6 1.2e-08 34.7 0.5 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 ORX93256.1 - 8.8e-09 35.3 0.0 3.1e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 ORX93256.1 - 7.5e-08 32.4 0.2 7.5e-08 32.4 0.2 2.9 3 0 0 3 3 3 2 RNA binding motif FXMRP1_C_core PF12235.8 ORX93256.1 - 0.025 15.2 9.8 0.025 15.2 9.8 1.8 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DUF4624 PF15417.6 ORX93256.1 - 0.035 13.9 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) HSA PF07529.13 ORX93257.1 - 6.5e-17 61.6 3.2 6.5e-17 61.6 3.2 2.8 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.6 ORX93257.1 - 0.00027 21.1 1.5 0.00098 19.3 1.5 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX93257.1 - 0.033 14.4 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SDA1 PF05285.12 ORX93257.1 - 4.5 6.6 13.4 0.2 11.0 0.5 2.4 2 0 0 2 2 2 0 SDA1 SH3_1 PF00018.28 ORX93258.1 - 0.00017 21.1 0.1 0.00029 20.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX93258.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORX93258.1 - 0.0013 18.6 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DNA_pol_delta_4 PF04081.13 ORX93259.1 - 0.045 14.1 0.6 0.9 9.9 0.2 2.7 2 1 0 2 2 2 0 DNA polymerase delta, subunit 4 Pkinase PF00069.25 ORX93260.1 - 3.5e-60 203.6 0.1 4.3e-60 203.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93260.1 - 1.4e-26 93.3 0.1 3.1e-26 92.2 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 ORX93260.1 - 4.5e-05 23.2 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORX93260.1 - 0.00029 20.3 0.2 0.00046 19.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX93260.1 - 0.0011 18.6 1.3 0.0031 17.1 0.2 2.0 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 ORX93260.1 - 0.0014 18.0 0.0 0.007 15.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORX93260.1 - 0.0021 18.0 0.0 0.58 10.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX93260.1 - 0.0037 16.1 0.1 0.0068 15.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase PglD_N PF17836.1 ORX93260.1 - 0.066 13.9 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain DDE_Tnp_Tn3 PF01526.17 ORX93260.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain BCS1_N PF08740.11 ORX93261.1 - 1.2e-51 175.3 0.2 1.8e-51 174.8 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORX93261.1 - 1e-20 74.5 0.0 1.7e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX93261.1 - 0.00044 20.7 0.0 0.0019 18.6 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORX93261.1 - 0.0011 19.5 0.0 0.0026 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORX93261.1 - 0.0021 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 ORX93261.1 - 0.0028 16.9 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 ORX93261.1 - 0.0057 16.6 0.0 0.034 14.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORX93261.1 - 0.0064 16.9 0.0 0.017 15.5 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_21 PF13304.6 ORX93261.1 - 0.0078 16.0 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 ORX93261.1 - 0.012 15.6 0.4 0.77 9.7 0.0 2.6 2 1 1 3 3 3 0 NACHT domain AAA_24 PF13479.6 ORX93261.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX93261.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORX93261.1 - 0.014 15.9 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 ORX93261.1 - 0.029 14.3 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 ORX93261.1 - 0.029 13.9 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 ORX93261.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX93261.1 - 0.063 13.6 0.0 0.21 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ORX93261.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 ORX93261.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PPV_E1_C PF00519.17 ORX93261.1 - 0.099 11.5 0.0 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase Cwf_Cwc_15 PF04889.12 ORX93262.1 - 1.4e-79 267.3 32.3 5.8e-79 265.3 32.3 1.7 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 ORX93262.1 - 0.032 14.1 22.5 0.047 13.5 22.5 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Nop14 PF04147.12 ORX93262.1 - 0.077 11.2 24.7 0.085 11.1 24.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORX93262.1 - 1.2 7.3 20.3 1.3 7.2 20.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 ORX93262.1 - 2.2 8.2 7.4 3.2 7.7 7.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A FmiP_Thoc5 PF09766.9 ORX93262.1 - 3.3 6.9 19.4 4.4 6.5 19.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 WDCP PF15390.6 ORX93262.1 - 3.8 5.8 9.4 4.7 5.5 9.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SpoIIIAH PF12685.7 ORX93262.1 - 5.1 6.9 16.3 6.6 6.5 16.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1752 PF08550.10 ORX93263.1 - 6.9e-11 41.8 2.4 1.3e-10 40.9 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Mt_ATP-synt_D PF05873.12 ORX93264.1 - 5.4e-20 71.8 5.6 6.5e-20 71.6 5.6 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Pet20 PF08692.10 ORX93264.1 - 0.0011 19.6 0.1 0.0025 18.5 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial protein Pet20 HMMR_N PF15905.5 ORX93264.1 - 0.0062 16.0 4.0 0.008 15.7 4.0 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ZapB PF06005.12 ORX93264.1 - 0.059 13.8 2.3 0.84 10.1 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB BST2 PF16716.5 ORX93264.1 - 0.073 13.7 5.3 0.1 13.2 1.6 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4618 PF15397.6 ORX93264.1 - 0.1 12.0 5.4 0.14 11.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HALZ PF02183.18 ORX93264.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 ORX93264.1 - 0.18 11.6 4.4 0.82 9.5 1.7 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2570 PF10828.8 ORX93264.1 - 0.55 10.1 4.8 0.57 10.0 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2570) Spore_III_AB PF09548.10 ORX93278.1 - 0.079 13.1 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Tom37 PF10568.9 ORX93278.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein ABC_tran PF00005.27 ORX93279.1 - 2.3e-49 167.4 0.0 5.7e-27 94.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORX93279.1 - 2.6e-46 158.5 42.1 3.6e-26 92.4 19.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORX93279.1 - 8.4e-09 35.2 5.5 0.00017 21.1 0.1 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORX93279.1 - 0.00011 22.3 0.5 0.38 10.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX93279.1 - 0.00017 22.0 1.2 0.52 10.7 0.1 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 ORX93279.1 - 0.00099 18.8 0.6 0.77 9.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORX93279.1 - 0.0012 18.8 0.5 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 ORX93279.1 - 0.006 16.7 1.3 1.4 9.0 0.2 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 ORX93279.1 - 0.061 13.4 4.2 0.32 11.0 0.1 2.9 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.6 ORX93279.1 - 0.13 12.6 1.2 10 6.4 0.1 3.1 2 1 0 2 2 2 0 AAA domain PTPRCAP PF15713.5 ORX93279.1 - 9.5 6.5 10.4 0.11 12.7 0.7 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated AMP-binding PF00501.28 ORX93280.1 - 0 2235.9 0.1 1.2e-103 347.0 0.0 9.1 7 1 1 8 8 8 8 AMP-binding enzyme Condensation PF00668.20 ORX93280.1 - 0 1443.2 0.0 2.2e-109 366.2 0.0 9.1 8 1 1 9 9 9 9 Condensation domain AMP-binding_C PF13193.6 ORX93280.1 - 6.2e-108 353.9 31.7 2e-15 57.5 0.4 7.8 7 0 0 7 7 7 7 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX93280.1 - 3.5e-69 229.1 20.2 3.4e-09 36.9 0.2 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site RHH_5 PF07878.11 ORX93280.1 - 4.1e-09 36.2 0.7 0.52 10.2 0.0 6.0 5 0 0 5 5 5 3 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF2690 PF10901.8 ORX93280.1 - 4e-08 33.4 0.0 12 6.3 0.0 5.5 5 0 0 5 5 5 2 Protein of unknown function (DUF2690) T4_Gp59_C PF08994.10 ORX93280.1 - 4.4e-07 30.5 2.7 3 8.5 0.0 5.8 5 0 0 5 5 5 1 T4 gene Gp59 loader of gp41 DNA helicase C-term HEAT_EZ PF13513.6 ORX93280.1 - 2e-05 25.0 9.3 24 5.6 0.0 7.5 6 0 0 6 6 6 0 HEAT-like repeat PAS_8 PF13188.7 ORX93280.1 - 0.0002 21.3 1.0 81 3.4 0.1 6.1 7 0 0 7 7 7 0 PAS domain MOZART1 PF12554.8 ORX93280.1 - 0.0097 15.7 11.3 47 3.9 0.1 6.0 6 0 0 6 6 6 0 Mitotic-spindle organizing gamma-tubulin ring associated ALF PF03752.13 ORX93280.1 - 0.025 14.6 1.2 44 4.2 0.0 4.5 4 0 0 4 4 4 0 Short repeats of unknown function DUF2733 PF10813.8 ORX93280.1 - 1.2 9.0 4.3 42 4.0 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2733) GPI-anchored PF10342.9 ORX93287.1 - 0.00081 20.1 0.2 0.0015 19.3 0.2 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CLPTM1 PF05602.12 ORX93287.1 - 0.12 11.3 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) GST_N_4 PF17172.4 ORX93288.1 - 2.4e-20 73.1 0.0 4.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORX93288.1 - 5.5e-08 32.5 0.1 9.9e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORX93288.1 - 3.6e-07 30.5 0.0 5.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 ORX93288.1 - 1.4e-05 25.0 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX93288.1 - 0.0033 17.6 0.2 0.014 15.6 0.2 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX93288.1 - 0.0055 16.9 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC2_membrane PF01061.24 ORX93289.1 - 2.5e-77 259.0 59.4 2.8e-47 160.9 18.8 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 ORX93289.1 - 3.4e-35 119.8 2.7 5.4e-25 87.1 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 ORX93289.1 - 7.7e-35 120.4 0.0 7.5e-19 68.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 ORX93289.1 - 1.5e-13 51.2 0.0 4.2e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORX93289.1 - 1.8e-10 40.4 35.4 5.7e-06 25.7 10.9 3.0 2 2 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX93289.1 - 8.7e-06 25.7 0.1 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ORX93289.1 - 1.8e-05 24.7 0.0 0.072 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORX93289.1 - 0.00012 22.5 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX93289.1 - 0.00014 21.5 0.0 0.0064 16.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORX93289.1 - 0.0007 19.2 0.1 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORX93289.1 - 0.00083 19.9 0.0 0.047 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX93289.1 - 0.017 15.4 0.1 0.63 10.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORX93289.1 - 0.019 14.6 0.1 0.078 12.6 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORX93289.1 - 0.027 14.6 0.0 0.081 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX93289.1 - 0.029 14.5 0.2 11 6.1 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 ORX93289.1 - 0.08 13.2 0.2 0.62 10.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain DUF1398 PF07166.11 ORX93289.1 - 0.12 12.5 0.0 4 7.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1398) Zeta_toxin PF06414.12 ORX93289.1 - 0.14 11.5 0.1 1.7 7.9 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_13 PF13166.6 ORX93289.1 - 0.16 10.6 0.6 0.9 8.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 ORX93289.1 - 0.22 11.2 0.1 2.7 7.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain OCD_Mu_crystall PF02423.15 ORX93289.1 - 0.25 10.2 0.0 2.9 6.7 0.0 2.0 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family AAA_23 PF13476.6 ORX93289.1 - 0.35 11.3 0.7 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.7 ORX93290.1 - 5.4e-18 66.0 0.0 7.4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX93290.1 - 3.1e-06 27.4 0.0 4.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ORX93290.1 - 0.0089 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Phage_antiter_Q PF06323.11 ORX93290.1 - 0.026 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q EamA PF00892.20 ORX93291.1 - 1.4e-09 38.3 36.4 4.6e-08 33.3 5.2 2.4 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORX93291.1 - 0.0023 17.2 12.9 0.0037 16.5 12.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 ORX93291.1 - 0.013 14.7 20.4 0.094 11.9 20.4 2.0 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Sulfate_transp PF00916.20 ORX93293.1 - 5.8e-87 291.9 19.9 8.1e-87 291.4 19.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX93293.1 - 2.4e-20 72.3 0.0 4.9e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORX93293.1 - 4.4e-05 23.8 4.6 4.4e-05 23.8 4.6 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily DUF4052 PF13261.6 ORX93293.1 - 0.043 13.6 4.5 0.14 12.0 4.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4052) NAD_Gly3P_dh_N PF01210.23 ORX93294.1 - 1.9e-53 180.6 0.0 3.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORX93294.1 - 6.7e-48 162.6 0.4 1.5e-47 161.5 0.4 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORX93294.1 - 0.029 14.9 0.2 0.54 10.9 0.2 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BRCA-2_OB1 PF09103.10 ORX93295.1 - 1.4e-24 86.4 0.1 1.8e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 ORX93295.1 - 2.6e-14 53.3 1.6 3.7e-14 52.8 1.6 1.2 1 0 0 1 1 1 1 BRCA2, helical ATP19 PF11022.8 ORX93296.1 - 7.9e-21 74.2 0.0 9.3e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K zinc_ribbon_10 PF10058.9 ORX93297.1 - 4.5e-20 71.1 0.7 7.6e-20 70.4 0.7 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Peptidase_U4 PF03419.13 ORX93297.1 - 0.059 12.7 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA NOA36 PF06524.12 ORX93297.1 - 0.059 12.7 6.5 0.1 11.9 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L29e PF01779.17 ORX93298.1 - 1.4e-24 86.1 11.5 1.9e-24 85.7 11.5 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Tctex-1 PF03645.13 ORX93299.1 - 1e-25 90.0 3.8 1.2e-25 89.7 3.8 1.1 1 0 0 1 1 1 1 Tctex-1 family Beta_helix PF13229.6 ORX93299.1 - 0.014 15.2 1.4 0.02 14.8 1.4 1.3 1 0 0 1 1 1 0 Right handed beta helix region G_path_suppress PF15991.5 ORX93300.1 - 0.032 14.4 8.5 0.13 12.4 8.5 2.0 1 1 0 1 1 1 0 G-protein pathway suppressor DUF2383 PF09537.10 ORX93300.1 - 0.093 13.1 2.4 2 8.8 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) Tcp11 PF05794.13 ORX93301.1 - 2.2e-84 284.1 10.5 2.2e-84 284.1 10.5 2.0 2 0 0 2 2 2 1 T-complex protein 11 IQ PF00612.27 ORX93301.1 - 0.012 15.3 0.6 0.044 13.6 0.3 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif GAPES4 PF17157.4 ORX93301.1 - 0.06 13.8 1.6 11 6.5 0.0 4.0 3 1 1 4 4 4 0 Gammaproteobacterial periplasmic sensor domain DFRP_C PF16543.5 ORX93301.1 - 1.6 9.3 5.0 1.8 9.1 0.4 3.0 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 Pkinase PF00069.25 ORX93302.1 - 3.6e-45 154.4 0.0 1.2e-25 90.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93302.1 - 7.1e-24 84.5 0.0 2.6e-11 43.3 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORX93302.1 - 2.6e-07 30.3 0.0 0.0023 17.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORX93302.1 - 0.0011 19.0 0.0 0.19 11.6 0.0 2.6 1 1 2 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORX93302.1 - 0.064 12.8 0.0 0.33 10.5 0.0 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase ELFV_dehydrog_N PF02812.18 ORX93303.1 - 3.2e-59 198.5 0.0 5.4e-59 197.7 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX93303.1 - 7.9e-52 176.4 1.1 5.2e-50 170.4 0.1 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AhpC-TSA PF00578.21 ORX93303.1 - 0.004 17.1 0.0 0.031 14.2 0.0 2.3 2 1 0 2 2 2 1 AhpC/TSA family 2-Hacid_dh_C PF02826.19 ORX93303.1 - 0.021 14.2 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORX93303.1 - 0.031 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog_N PF02812.18 ORX93304.1 - 2.7e-59 198.7 0.0 4.9e-59 197.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX93304.1 - 1.1e-51 175.9 0.6 6.8e-50 170.1 0.1 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AhpC-TSA PF00578.21 ORX93304.1 - 0.026 14.4 0.0 0.092 12.7 0.0 1.9 1 0 0 1 1 1 0 AhpC/TSA family 2-Hacid_dh_C PF02826.19 ORX93304.1 - 0.029 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog_N PF02812.18 ORX93305.1 - 3.2e-59 198.5 0.0 5.4e-59 197.7 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX93305.1 - 5e-52 177.1 0.9 5.4e-50 170.4 0.1 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AhpC-TSA PF00578.21 ORX93305.1 - 0.0023 17.9 0.0 0.018 15.0 0.0 2.4 2 1 0 2 2 2 1 AhpC/TSA family 2-Hacid_dh_C PF02826.19 ORX93305.1 - 0.022 14.1 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORX93305.1 - 0.032 14.7 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Arrestin_C PF02752.22 ORX93321.1 - 6.5e-08 33.1 0.0 2.6e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX93321.1 - 7.8e-05 22.8 0.1 0.0005 20.2 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CYYR1 PF10873.8 ORX93321.1 - 0.3 11.5 3.1 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Aminotran_1_2 PF00155.21 ORX93323.1 - 2.4e-64 217.8 0.0 2.7e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Fer2 PF00111.27 ORX93323.1 - 0.0043 17.0 0.4 0.098 12.6 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Aminotran_MocR PF12897.7 ORX93323.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 ORX93323.1 - 0.087 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 ORX93323.1 - 0.23 10.3 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Allinase LRR_4 PF12799.7 ORX93324.1 - 4.5e-06 26.9 6.3 0.58 10.7 0.0 5.7 3 3 3 6 6 6 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORX93324.1 - 0.00017 21.4 1.1 0.00074 19.4 0.6 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 ORX93324.1 - 0.0051 16.6 2.4 1.4 8.7 0.2 4.4 3 2 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 ORX93324.1 - 0.35 11.0 4.7 6.6 7.1 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat F-box PF00646.33 ORX93324.1 - 1.9 8.4 7.3 0.41 10.6 0.3 3.3 3 1 0 3 3 3 0 F-box domain UPF0121 PF03661.13 ORX93326.1 - 4.9e-36 124.3 3.5 6.2e-36 124.0 3.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Copine PF07002.16 ORX93327.1 - 1.7e-60 204.2 0.0 2.4e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 ORX93327.1 - 8.6e-18 64.5 0.0 5.3e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 ORX93327.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus VWA PF00092.28 ORX93327.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Copine PF07002.16 ORX93328.1 - 4.9e-56 189.6 0.0 6.9e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 ORX93328.1 - 4.7e-13 49.3 0.0 4.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain DNApol_Exo PF18136.1 ORX93329.1 - 4.5e-97 324.6 0.0 8.9e-97 323.6 0.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 ORX93329.1 - 3e-53 181.2 0.0 5.3e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DUF2834 PF11196.8 ORX93330.1 - 0.0077 16.6 1.2 0.0077 16.6 1.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2834) Dicty_CAR PF05462.11 ORX93330.1 - 1.5 7.9 11.5 3.9 6.5 11.5 1.9 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor ABC2_membrane_5 PF13346.6 ORX93330.1 - 5.9 6.4 18.6 0.054 13.0 4.5 2.7 2 1 1 3 3 3 0 ABC-2 family transporter protein FGase PF05013.12 ORX93331.1 - 1.1e-07 32.3 0.1 0.012 15.9 0.0 2.9 1 1 1 2 2 2 2 N-formylglutamate amidohydrolase Mito_carr PF00153.27 ORX93332.1 - 2.2e-55 184.6 1.2 1.5e-18 66.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5058 PF16481.5 ORX93332.1 - 0.0062 16.3 1.1 2.1 8.0 0.2 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF5058) RabGAP-TBC PF00566.18 ORX93333.1 - 1.1e-34 120.0 2.1 6.5e-29 101.1 0.2 2.8 3 0 0 3 3 3 2 Rab-GTPase-TBC domain CXCL17 PF15211.6 ORX93334.1 - 0.21 12.4 8.4 0.22 12.3 5.0 2.4 1 1 1 2 2 2 0 VEGF co-regulated chemokine 1 CAP_GLY PF01302.25 ORX93336.1 - 1.2e-21 76.5 0.8 1.3e-21 76.3 0.8 1.0 1 0 0 1 1 1 1 CAP-Gly domain Acetyltransf_3 PF13302.7 ORX93337.1 - 1e-19 71.6 0.0 1.2e-19 71.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX93337.1 - 3.6e-06 27.2 0.0 4.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORX93337.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein UL2 PF08196.11 ORX93338.1 - 0.048 13.6 0.6 0.16 12.0 0.6 1.9 1 0 0 1 1 1 0 UL2 protein DUF3377 PF11857.8 ORX93338.1 - 3.2 7.8 6.7 1.6 8.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) zf-H2C2_2 PF13465.6 ORX93347.1 - 1.9e-16 59.6 12.5 5.4e-09 36.1 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX93347.1 - 1.9e-09 37.4 20.0 0.00012 22.4 4.3 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93347.1 - 5.1e-09 36.2 17.9 0.00033 21.2 2.8 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX93347.1 - 2e-07 31.1 5.1 0.039 14.2 0.8 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 ORX93347.1 - 0.0012 18.7 8.0 1.7 8.6 0.4 3.2 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger PyrI_C PF02748.15 ORX93347.1 - 0.014 15.3 11.4 1.3 8.9 0.0 2.7 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 ORX93347.1 - 0.03 14.7 9.1 1.6 9.2 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX93347.1 - 0.038 14.0 16.1 0.35 10.9 2.1 3.3 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORX93347.1 - 0.09 13.1 8.7 2.2 8.7 5.6 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 ORX93347.1 - 0.28 11.9 10.4 0.53 11.0 5.8 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.15 ORX93347.1 - 0.28 11.2 8.4 0.73 9.9 1.8 2.8 1 1 2 3 3 3 0 BED zinc finger DUF448 PF04296.13 ORX93347.1 - 0.29 11.0 2.7 1.7 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF448) IBR PF01485.21 ORX93347.1 - 0.51 10.6 10.4 0.3 11.4 8.4 1.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-Paramyx-P PF13008.7 ORX93347.1 - 0.69 9.4 6.6 4.2 6.9 3.6 2.3 2 1 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein Evr1_Alr PF04777.13 ORX93347.1 - 0.98 9.9 6.2 3.7 8.1 6.2 2.0 1 1 0 1 1 1 0 Erv1 / Alr family zf-AN1 PF01428.16 ORX93347.1 - 1 9.6 16.7 7.5 6.8 9.9 3.0 1 1 2 3 3 3 0 AN1-like Zinc finger HNH_5 PF14279.6 ORX93347.1 - 1.8 8.5 7.7 7.5 6.5 0.1 2.8 3 1 0 3 3 3 0 HNH endonuclease ArsB PF02040.15 ORX93348.1 - 2.1e-33 116.3 19.8 4.9e-20 72.3 11.3 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 ORX93348.1 - 6.2e-19 68.3 30.2 6.2e-19 68.3 30.2 1.9 1 1 1 2 2 2 1 Citrate transporter WD40 PF00400.32 ORX93349.1 - 1.3e-26 92.3 30.5 9e-06 26.3 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 ORX93349.1 - 4.5e-09 35.5 7.8 3e-06 26.2 0.3 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Sina PF03145.16 ORX93349.1 - 7e-09 35.9 0.6 1.2e-08 35.1 0.6 1.3 1 0 0 1 1 1 1 Seven in absentia protein family WD40_like PF17005.5 ORX93349.1 - 2.1e-06 27.3 0.1 1.6e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 ORX93349.1 - 3.1e-05 24.2 0.8 0.37 11.1 0.1 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORX93349.1 - 0.0001 22.6 2.1 0.76 10.3 0.1 4.4 5 0 0 5 5 5 2 PQQ-like domain zf-TRAF PF02176.18 ORX93349.1 - 0.00011 22.8 2.9 0.00044 20.9 2.4 2.3 1 1 0 1 1 1 1 TRAF-type zinc finger Nucleoporin_N PF08801.11 ORX93349.1 - 0.00013 20.9 1.6 0.033 12.9 0.0 3.6 1 1 0 2 2 2 1 Nup133 N terminal like DUF5046 PF16465.5 ORX93349.1 - 0.014 14.9 0.2 0.65 9.4 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5046) zf-TRAF_2 PF15965.5 ORX93349.1 - 0.017 15.6 0.5 0.071 13.6 0.5 2.1 1 0 0 1 1 1 0 TRAF-like zinc-finger Ge1_WD40 PF16529.5 ORX93349.1 - 0.017 14.1 2.7 0.3 10.0 0.4 2.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 ORX93349.1 - 0.058 13.0 0.0 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain UPF0449 PF15136.6 ORX93349.1 - 0.06 13.8 0.4 0.14 12.6 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Spc29 PF17082.5 ORX93349.1 - 0.11 12.3 0.2 0.11 12.3 0.2 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF641 PF04859.12 ORX93349.1 - 0.21 11.9 0.5 0.33 11.3 0.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) VGPC1_C PF16799.5 ORX93349.1 - 0.57 10.2 2.4 1.4 9.0 2.4 1.6 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 PKcGMP_CC PF16808.5 ORX93349.1 - 0.57 10.1 4.0 1.1 9.2 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Cpn60_TCP1 PF00118.24 ORX93350.1 - 1.9e-120 402.8 11.2 3.2e-120 402.1 11.2 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 ORX93350.1 - 0.023 14.9 0.1 0.061 13.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 ORX93350.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Syntaxin PF00804.25 ORX93352.1 - 1.2e-29 103.4 13.8 1.6e-29 103.0 13.8 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORX93352.1 - 6.3e-06 26.1 0.8 1.2e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 ORX93352.1 - 4.3e-05 23.8 8.0 4.3e-05 23.8 8.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 ORX93352.1 - 0.0089 16.6 1.9 0.0089 16.6 1.9 2.6 3 0 0 3 3 3 1 Syntaxin 6, N-terminal GHL15 PF14885.6 ORX93352.1 - 0.011 15.8 2.3 0.049 13.6 0.4 2.1 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 15 SKA1 PF07160.12 ORX93352.1 - 0.013 15.3 1.8 0.013 15.3 1.8 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DAPDH_C PF16654.5 ORX93352.1 - 0.017 14.9 0.4 0.048 13.5 0.2 1.9 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Vac_Fusion PF02346.16 ORX93352.1 - 0.13 12.0 2.9 0.15 11.7 0.2 2.5 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 V-SNARE PF05008.15 ORX93352.1 - 0.88 10.0 9.4 0.28 11.6 0.5 3.3 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF948 PF06103.11 ORX93352.1 - 2 8.8 6.6 23 5.3 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyoxalase_2 PF12681.7 ORX93352.1 - 3.6 7.6 7.4 3 7.8 0.2 2.9 3 0 0 3 3 3 0 Glyoxalase-like domain FlaC_arch PF05377.11 ORX93352.1 - 8.2 6.9 8.7 1.8 9.0 0.1 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 ORX93352.1 - 8.6 6.5 14.5 7.7 6.7 1.5 2.5 2 1 0 2 2 2 0 Tropomyosin like F-box PF00646.33 ORX93353.1 - 0.022 14.6 0.8 0.062 13.2 0.8 1.8 1 1 0 1 1 1 0 F-box domain JmjC PF02373.22 ORX93354.1 - 1.1e-41 141.9 2.4 1.1e-41 141.9 2.4 2.3 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.17 ORX93354.1 - 4.2e-13 49.0 1.3 1.1e-12 47.7 1.3 1.7 1 0 0 1 1 1 1 jmjN domain DSPc PF00782.20 ORX93355.1 - 4.1e-06 26.7 0.0 6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX93355.1 - 2.3e-05 24.1 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORX93355.1 - 0.00061 19.5 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) WW PF00397.26 ORX93356.1 - 1e-07 31.9 0.6 2.1e-07 30.9 0.6 1.6 1 0 0 1 1 1 1 WW domain CUE PF02845.16 ORX93357.1 - 8.1e-09 35.0 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 CUE domain Peptidase_M28 PF04389.17 ORX93358.1 - 3.5e-31 108.4 0.0 7.2e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORX93358.1 - 1.6e-08 34.5 0.0 3.4e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 UL141 PF16758.5 ORX93358.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Herpes-like virus membrane glycoprotein UL141 Sec7 PF01369.20 ORX93359.1 - 8.4e-45 152.7 0.1 4.9e-44 150.2 0.0 1.9 2 0 0 2 2 2 1 Sec7 domain Lactamase_B PF00753.27 ORX93360.1 - 1.3e-07 31.8 0.0 3.7e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX93360.1 - 2.4e-06 27.2 0.1 5e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF667 PF05018.13 ORX93362.1 - 1.6e-73 246.4 0.1 1.8e-73 246.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Cation_efflux PF01545.21 ORX93363.1 - 2.7e-16 59.9 0.2 2.8e-16 59.8 0.2 1.0 1 0 0 1 1 1 1 Cation efflux family Bac_globin PF01152.21 ORX93365.1 - 6.1e-12 45.8 0.2 7.8e-12 45.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX93365.1 - 0.0023 17.8 0.2 0.0063 16.4 0.1 1.7 1 1 0 1 1 1 1 Protoglobin UPF0147 PF03685.13 ORX93365.1 - 0.025 14.6 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DUF4918 PF16265.5 ORX93365.1 - 0.039 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) TetR_C_22 PF17928.1 ORX93365.1 - 0.072 13.4 0.2 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BioW PF03744.13 ORX93365.1 - 0.078 12.5 0.1 0.094 12.3 0.1 1.1 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase zf-C3HC4_3 PF13920.6 ORX93366.1 - 0.00029 20.6 11.8 0.00029 20.6 11.8 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HMG_box PF00505.19 ORX93368.1 - 4.8e-21 74.9 0.1 5.3e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX93368.1 - 1.4e-06 28.8 0.0 1.6e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 ORX93368.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain HTH_24 PF13412.6 ORX93368.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ACT_7 PF13840.6 ORX93369.1 - 2.6e-29 100.8 0.0 2.3e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 ORX93369.1 - 1e-09 38.0 4.8 0.00038 20.2 0.0 3.4 4 0 0 4 4 4 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT PF01842.25 ORX93369.1 - 0.13 12.0 0.0 1.9 8.3 0.0 2.6 2 1 0 2 2 2 0 ACT domain adh_short PF00106.25 ORX93371.1 - 6.7e-40 136.6 0.5 8.3e-40 136.3 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93371.1 - 3.2e-33 115.2 0.1 3.9e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93371.1 - 5e-12 46.1 0.2 9.2e-12 45.2 0.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX93371.1 - 9.6e-08 32.1 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ORX93371.1 - 2.5e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 ORX93371.1 - 0.011 14.9 0.1 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 ORX93371.1 - 0.093 12.3 0.0 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Catalase-rel PF06628.12 ORX93381.1 - 0.14 12.4 0.0 0.98 9.7 0.0 2.4 1 1 1 2 2 2 0 Catalase-related immune-responsive DUF1542 PF07564.11 ORX93381.1 - 2.8 8.1 5.5 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) UQ_con PF00179.26 ORX93382.1 - 2.9e-22 78.8 0.1 4.4e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX93382.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 RWD domain HMG_box PF00505.19 ORX93383.1 - 2.7e-17 62.9 3.0 7.8e-17 61.5 3.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX93383.1 - 8.7e-08 32.7 3.2 2.5e-07 31.2 2.6 2.2 1 1 0 1 1 1 1 HMG-box domain IATP PF04568.12 ORX93383.1 - 0.00075 19.9 1.7 0.0019 18.6 1.7 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP V_ATPase_I PF01496.19 ORX93383.1 - 0.067 11.1 8.6 0.08 10.8 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TEX19 PF15553.6 ORX93383.1 - 1.1 9.3 4.3 1.8 8.5 4.3 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 CDC45 PF02724.14 ORX93383.1 - 7.5 4.7 17.7 9.4 4.4 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 ORX93383.1 - 8.9 5.0 16.9 9.7 4.9 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAD_binding_1 PF00667.20 ORX93384.1 - 9.2e-56 188.9 0.0 1.4e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX93384.1 - 1.2e-30 106.6 0.1 4.2e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORX93384.1 - 1.3e-18 67.6 0.0 3.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain La PF05383.17 ORX93385.1 - 1.2e-20 73.3 0.1 3.5e-20 71.8 0.1 1.9 1 0 0 1 1 1 1 La domain DUF5444 PF17519.2 ORX93385.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5444) Hist_deacetyl PF00850.19 ORX93386.1 - 3.3e-85 286.3 0.0 4.3e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Ndc80_HEC PF03801.13 ORX93387.1 - 6.8e-48 162.2 0.1 2.4e-47 160.4 0.1 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 ORX93387.1 - 6.1e-05 23.0 4.6 6.1e-05 23.0 4.6 4.4 3 2 0 3 3 3 1 Domain of unknown function (DUF5595) Lebercilin PF15619.6 ORX93387.1 - 0.0094 15.6 14.8 0.0094 15.6 14.8 3.3 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 ORX93387.1 - 0.08 11.8 37.0 0.11 11.4 11.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 ORX93387.1 - 0.14 11.4 22.7 0.42 9.9 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 ORX93387.1 - 0.61 7.5 40.4 0.67 7.4 18.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 ORX93387.1 - 1.6 7.5 47.4 1.1 8.1 17.4 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 ORX93387.1 - 2.9 8.3 44.0 0.049 14.1 16.9 3.0 2 1 0 2 2 2 0 Fez1 z-alpha PF02295.17 ORX93387.1 - 9.3 6.4 8.2 1.1 9.4 2.6 2.3 2 1 0 2 2 2 0 Adenosine deaminase z-alpha domain DUF1115 PF06544.12 ORX93388.1 - 1.2e-11 44.9 0.2 5.8e-11 42.7 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) RWD PF05773.22 ORX93388.1 - 1.8e-09 37.9 0.1 3.7e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 RWD domain Cmc1 PF08583.10 ORX93389.1 - 1.2e-16 60.4 3.3 1.5e-16 60.2 3.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 ORX93389.1 - 0.00013 22.2 1.1 0.00014 22.1 1.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.13 ORX93389.1 - 0.016 15.5 0.7 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF4756 PF15948.5 ORX93389.1 - 0.039 13.8 0.2 0.044 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) CHCH PF06747.13 ORX93389.1 - 0.068 13.3 3.1 6.8 7.0 0.3 2.3 2 0 0 2 2 2 0 CHCH domain PADR1 PF08063.12 ORX93389.1 - 0.074 12.8 0.6 1.5 8.7 0.1 2.0 1 1 1 2 2 2 0 PADR1 (NUC008) domain Mg_trans_NIPA PF05653.14 ORX93390.1 - 5.1e-25 88.2 9.4 1.9e-12 47.0 2.4 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA DLH PF01738.18 ORX93391.1 - 3.4e-19 69.2 0.0 3.9e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Arf PF00025.21 ORX93392.1 - 3.2e-67 225.3 0.0 3.6e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORX93392.1 - 1.9e-10 40.5 0.0 5.9e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORX93392.1 - 1.3e-09 37.8 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORX93392.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX93392.1 - 1.6e-07 31.1 0.0 2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 ORX93392.1 - 2.1e-07 31.0 0.0 3.8e-07 30.2 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX93392.1 - 3.5e-06 26.5 0.0 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 ORX93392.1 - 0.046 13.5 0.1 0.13 12.0 0.0 1.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation UPF0220 PF05255.11 ORX93393.1 - 1e-49 168.3 1.0 1.3e-49 168.0 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3450 PF11932.8 ORX93394.1 - 0.15 11.3 5.3 0.23 10.7 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TRAPP PF04051.16 ORX93395.1 - 1.7e-39 134.9 0.1 2e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Spc42p PF11544.8 ORX93395.1 - 0.066 13.2 0.7 24 5.0 0.2 3.0 3 0 0 3 3 3 0 Spindle pole body component Spc42p TMP-TENI PF02581.17 ORX93396.1 - 3.7e-23 81.8 0.0 6.3e-23 81.0 0.0 1.4 1 1 0 1 1 1 1 Thiamine monophosphate synthase NMO PF03060.15 ORX93396.1 - 0.075 12.4 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF5321 PF17254.2 ORX93397.1 - 2.7e-08 33.4 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Nop14 PF04147.12 ORX93397.1 - 0.0043 15.3 2.6 0.0076 14.5 2.0 1.5 1 1 0 2 2 2 1 Nop14-like family PilJ PF13675.6 ORX93397.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1949 PF09186.11 ORX93397.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) DJ-1_PfpI PF01965.24 ORX93398.1 - 5.4e-17 62.1 0.0 6.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 ORX93398.1 - 0.0035 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain NDT80_PhoG PF05224.12 ORX93400.1 - 2.3e-36 125.8 0.0 4.1e-36 124.9 0.0 1.4 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Ribonuc_red_lgC PF02867.15 ORX93401.1 - 2.7e-192 639.9 0.0 3.6e-192 639.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ORX93401.1 - 1.4e-23 82.7 0.3 4.2e-23 81.1 0.1 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ORX93401.1 - 1e-16 61.3 0.1 2.8e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Prok-E2_B PF14461.6 ORX93401.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B Zip PF02535.22 ORX93402.1 - 2.1e-58 198.1 9.0 6.9e-58 196.4 9.0 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1275 PF06912.11 ORX93402.1 - 0.02 14.8 3.3 0.077 12.9 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1275) Ribosom_S12_S23 PF00164.25 ORX93403.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DegQ PF08181.11 ORX93404.1 - 0.00084 19.4 0.8 0.0027 17.8 0.8 1.9 1 0 0 1 1 1 1 DegQ (SacQ) family LMBR1 PF04791.16 ORX93404.1 - 0.39 9.6 5.3 0.52 9.2 5.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 ORX93404.1 - 1 8.6 9.2 7.6 5.8 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 ORX93404.1 - 1.4 8.7 8.4 1.1 9.1 5.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 CorA PF01544.18 ORX93404.1 - 1.8 7.8 9.0 0.36 10.1 4.8 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein UPF0449 PF15136.6 ORX93404.1 - 3.9 8.0 8.1 1.8 9.1 3.7 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 ABC_tran PF00005.27 ORX93405.1 - 5.6e-45 153.2 0.0 1.1e-21 77.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORX93405.1 - 4.2e-22 78.0 1.8 4.2e-22 78.0 1.8 3.0 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 ORX93405.1 - 1.7e-20 74.0 1.0 0.00033 20.6 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX93405.1 - 2.6e-12 46.6 0.1 5.3e-05 22.7 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX93405.1 - 8.2e-09 35.1 0.1 0.0051 16.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORX93405.1 - 2.6e-08 34.1 0.0 0.0012 19.0 0.0 3.3 2 1 1 3 3 2 2 Dynamin family AAA_15 PF13175.6 ORX93405.1 - 6.9e-08 32.6 2.5 0.036 13.8 2.8 4.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 ORX93405.1 - 3.7e-06 27.3 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORX93405.1 - 4.1e-06 26.9 0.8 0.015 15.4 0.0 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 ORX93405.1 - 5.7e-06 26.7 0.0 0.032 14.5 0.1 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX93405.1 - 8.5e-06 25.8 0.2 0.016 15.1 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 ORX93405.1 - 9.2e-06 25.9 0.1 0.11 12.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 ORX93405.1 - 2.2e-05 25.0 0.0 0.31 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 ORX93405.1 - 2.9e-05 24.5 0.0 0.013 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 ORX93405.1 - 6.6e-05 22.6 0.3 0.19 11.3 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 ORX93405.1 - 9.8e-05 22.8 0.0 0.29 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 ORX93405.1 - 9.9e-05 22.1 0.8 0.45 10.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 ORX93405.1 - 0.00036 20.6 0.0 3.8 7.6 0.0 3.9 4 1 1 5 5 3 0 AAA domain AAA PF00004.29 ORX93405.1 - 0.00041 20.8 0.0 0.37 11.2 0.1 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 ORX93405.1 - 0.00087 18.7 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 ORX93405.1 - 0.0021 18.0 0.7 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 ORX93405.1 - 0.0021 18.1 0.3 0.48 10.4 0.0 3.2 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 ORX93405.1 - 0.0021 18.6 20.3 0.052 14.0 0.0 4.3 5 0 0 5 5 4 2 AAA domain G-alpha PF00503.20 ORX93405.1 - 0.0031 16.7 0.0 0.54 9.4 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.17 ORX93405.1 - 0.0033 17.5 1.7 2.3 8.3 0.0 3.4 4 0 0 4 4 3 1 Helicase HerA, central domain VirE PF05272.11 ORX93405.1 - 0.0047 16.7 0.0 5.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E MeaB PF03308.16 ORX93405.1 - 0.0062 15.5 0.0 2 7.4 0.0 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORX93405.1 - 0.0068 16.2 0.1 3 7.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORX93405.1 - 0.01 15.4 0.2 1.4 8.4 0.0 2.8 3 1 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 ORX93405.1 - 0.011 15.2 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.22 ORX93405.1 - 0.011 16.1 2.2 2.1 8.7 0.0 3.2 4 0 0 4 4 2 0 RNA helicase DUF948 PF06103.11 ORX93405.1 - 0.013 15.8 0.1 0.045 14.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MukB PF04310.12 ORX93405.1 - 0.024 14.4 0.0 3.2 7.5 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal Spore_IV_A PF09547.10 ORX93405.1 - 0.029 13.3 0.0 0.29 10.0 0.0 2.3 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) SbcCD_C PF13558.6 ORX93405.1 - 0.034 14.4 0.1 1.8 8.9 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 ORX93405.1 - 0.041 13.0 0.1 7.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 ORX93405.1 - 0.044 14.0 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORX93405.1 - 0.048 13.4 0.6 7 6.3 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ORX93405.1 - 0.048 13.4 0.3 14 5.4 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Borrelia_REV PF03978.13 ORX93405.1 - 0.069 13.1 3.2 0.12 12.3 0.3 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein CLP1_P PF16575.5 ORX93405.1 - 0.075 12.8 0.1 8.7 6.1 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 ORX93405.1 - 0.08 12.4 1.4 2.6 7.5 0.0 3.3 3 1 1 4 4 4 0 P-loop containing dynein motor region T2SSE PF00437.20 ORX93405.1 - 0.084 11.9 0.0 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 ORX93405.1 - 0.093 11.9 0.0 2.5 7.2 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.19 ORX93405.1 - 0.11 12.1 0.3 5 6.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 ORX93405.1 - 0.15 11.4 0.1 2.4 7.5 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI EIIA-man PF03610.16 ORX93405.1 - 0.53 10.5 2.7 2.6 8.3 0.1 2.7 3 0 0 3 3 3 0 PTS system fructose IIA component MutS_V PF00488.21 ORX93405.1 - 0.85 9.6 2.4 37 4.3 0.0 3.0 3 0 0 3 3 3 0 MutS domain V DUF4078 PF13300.6 ORX93406.1 - 3.7e-21 75.2 12.4 3.7e-21 75.2 12.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) DUF2203 PF09969.9 ORX93406.1 - 9.1 7.0 12.1 6.6 7.5 1.6 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ALAD PF00490.21 ORX93407.1 - 2.9e-124 414.4 0.0 3.5e-124 414.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase LRR_4 PF12799.7 ORX93408.1 - 0.0011 19.4 1.9 0.05 14.0 0.3 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX93408.1 - 0.0033 16.9 0.0 0.061 12.8 0.0 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 ORX93408.1 - 0.0082 15.9 0.8 0.12 12.2 0.8 2.5 2 0 0 2 2 2 1 Leucine rich repeat Pellino PF04710.14 ORX93408.1 - 0.028 13.1 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Pellino HSF_DNA-bind PF00447.17 ORX93409.1 - 2.1e-24 86.0 1.5 3.2e-24 85.4 1.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding ATG7_N PF16420.5 ORX93410.1 - 6.5e-88 295.2 0.0 8.7e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 ORX93410.1 - 6.2e-43 146.9 0.0 9.6e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 ORX93410.1 - 0.046 13.8 0.0 0.5 10.4 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Dus PF01207.17 ORX93411.1 - 2.6e-53 181.2 0.0 3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ORX93411.1 - 0.075 12.5 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein MTS PF05175.14 ORX93412.1 - 2.5e-05 23.9 0.0 0.00084 18.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX93412.1 - 0.00034 20.1 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 ORX93412.1 - 0.003 18.3 0.0 0.01 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93412.1 - 0.064 14.0 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Clr5 PF14420.6 ORX93412.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain UBX PF00789.20 ORX93413.1 - 1.2e-22 79.9 0.0 3.1e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 ORX93413.1 - 2.2e-10 40.2 0.0 5.4e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain SRP_SPB PF02978.19 ORX93413.1 - 0.11 13.1 6.0 4.2 8.1 7.4 2.7 2 1 0 2 2 2 0 Signal peptide binding domain zf-C2H2_2 PF12756.7 ORX93413.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.6 ORX93413.1 - 6.2 7.3 6.0 9.2 6.8 6.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PknG_rubred PF16919.5 ORX93414.1 - 0.014 15.6 3.3 0.62 10.2 0.4 2.0 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain CBFB_NFYA PF02045.15 ORX93416.1 - 1.4e-29 102.4 11.0 2e-29 102.0 11.0 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF4739 PF15893.5 ORX93416.1 - 0.082 12.4 0.3 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) Ribosomal_S30 PF04758.14 ORX93417.1 - 4.1e-29 100.6 9.6 4.4e-29 100.4 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 MFS_1 PF07690.16 ORX93418.1 - 4.5e-40 137.7 30.6 4e-36 124.7 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX93418.1 - 1.6e-14 53.6 0.7 1.6e-14 53.6 0.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORX93418.1 - 8.8e-07 28.1 11.9 0.0062 15.4 0.0 3.2 2 1 1 3 3 3 3 MFS_1 like family TRI12 PF06609.13 ORX93418.1 - 0.00089 17.8 0.9 0.0014 17.1 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PEPCK_GTP PF00821.18 ORX93423.1 - 1.1e-164 547.5 0.0 1.4e-164 547.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 ORX93423.1 - 7.2e-98 326.5 0.0 1.1e-97 325.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain DUF2433 PF10360.9 ORX93424.1 - 1.3e-14 54.4 0.0 1.8e-12 47.5 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 ORX93424.1 - 2.3e-07 30.6 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA PF00627.31 ORX93425.1 - 2.5e-28 97.5 3.2 8.2e-14 51.2 0.4 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 ORX93425.1 - 2.9e-22 78.2 0.9 4.9e-22 77.5 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 ORX93425.1 - 3.8e-22 77.8 16.5 7.3e-22 76.9 16.5 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 ORX93425.1 - 6.9e-09 35.4 1.4 1.4e-08 34.4 1.4 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 ORX93425.1 - 0.00027 20.7 0.2 0.88 9.4 0.0 3.3 4 0 0 4 4 4 2 Fungal ubiquitin-associated domain WIYLD PF10440.9 ORX93425.1 - 0.00047 19.9 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain HEPN_Toprim_N PF18871.1 ORX93425.1 - 0.0053 16.7 0.2 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 HEPN/Toprim N-terminal domain 1 Ubiquitin_2 PF14560.6 ORX93425.1 - 0.035 14.6 0.1 0.035 14.6 0.1 2.8 3 1 0 3 3 3 0 Ubiquitin-like domain LolA PF03548.15 ORX93425.1 - 0.041 13.6 1.4 0.13 11.9 0.1 2.3 2 1 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA TBK1_ULD PF18396.1 ORX93425.1 - 0.086 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORX93425.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L36e PF01158.18 ORX93426.1 - 3.5e-42 142.6 7.3 3.9e-42 142.4 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Mago-bind PF09282.10 ORX93426.1 - 0.23 11.4 1.7 7.4 6.5 0.2 2.6 2 0 0 2 2 2 0 Mago binding Arrestin_C PF02752.22 ORX93427.1 - 3e-17 63.3 0.9 9.8e-09 35.8 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX93427.1 - 9.8e-11 41.9 0.1 4.4e-10 39.8 0.1 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORX93427.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Rgp1 BRO1 PF03097.18 ORX93428.1 - 4.7e-128 427.3 6.1 1e-127 426.2 6.1 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORX93428.1 - 2.6e-55 187.8 9.4 2.6e-55 187.8 9.4 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Spc29 PF17082.5 ORX93428.1 - 0.053 13.3 0.2 0.053 13.3 0.2 3.6 2 1 1 3 3 3 0 Spindle Pole Component 29 DUF3240 PF11582.8 ORX93428.1 - 0.067 13.3 0.1 0.29 11.3 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) NKWYS PF10364.9 ORX93428.1 - 0.099 12.8 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein HTH_19 PF12844.7 ORX93428.1 - 0.34 11.0 1.4 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain MEIOC PF15189.6 ORX93428.1 - 0.96 9.0 8.3 13 5.4 0.0 4.0 4 0 0 4 4 4 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF5082 PF16888.5 ORX93428.1 - 5.7 7.2 8.7 4.1 7.7 1.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Aldose_epim PF01263.20 ORX93429.1 - 6.7e-46 157.0 0.3 7.6e-46 156.8 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase TPR_19 PF14559.6 ORX93430.1 - 0.11 13.0 0.1 0.14 12.7 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat CBM9_1 PF06452.11 ORX93431.1 - 6.6e-08 32.7 0.7 1.2e-07 31.8 0.2 1.7 2 0 0 2 2 2 1 Carbohydrate family 9 binding domain-like UL73_N PF12522.8 ORX93431.1 - 0.03 14.1 0.2 0.03 14.1 0.2 2.0 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Orthopox_B11R PF07033.11 ORX93432.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus B11R protein TOM13 PF08219.11 ORX93433.1 - 1.3e-17 63.5 0.6 2.7e-17 62.5 0.2 1.6 1 1 0 2 2 2 1 Outer membrane protein TOM13 Ion_trans PF00520.31 ORX93434.1 - 4.8e-22 78.4 20.4 6.1e-22 78.0 20.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 ORX93434.1 - 1.5e-11 44.1 6.6 1.5e-11 44.1 6.6 2.5 2 1 0 2 2 2 1 Ion channel Lig_chan PF00060.26 ORX93434.1 - 0.03 14.2 2.3 0.075 12.9 0.5 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel CLTH PF10607.9 ORX93435.1 - 5.9e-39 133.3 0.1 5.9e-39 133.3 0.1 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORX93435.1 - 3.3e-09 36.4 0.8 8.8e-09 35.0 0.2 2.0 2 0 0 2 2 2 1 LisH MoaE PF02391.17 ORX93436.1 - 3.2e-29 101.5 0.0 3.7e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 MoaE protein JAB PF01398.21 ORX93437.1 - 1.5e-33 115.2 0.0 3.2e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ORX93437.1 - 7.7e-15 55.3 1.2 1.3e-14 54.6 1.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 ORX93437.1 - 2.5e-06 27.3 0.0 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 ORX93437.1 - 0.0021 18.1 0.2 0.004 17.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Sec23_trunk PF04811.15 ORX93438.1 - 1.8e-74 250.4 0.0 2.4e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORX93438.1 - 5e-30 104.1 0.0 1e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORX93438.1 - 2e-25 88.6 0.1 4.2e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORX93438.1 - 1.9e-16 59.8 6.4 4.2e-16 58.7 6.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORX93438.1 - 4.4e-13 48.9 0.0 1.2e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORX93438.1 - 0.1 12.0 0.3 0.27 10.7 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Exo_endo_phos PF03372.23 ORX93439.1 - 6.7e-23 81.4 0.0 1.9e-22 79.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 ORX93439.1 - 4.1e-11 42.9 7.7 2.4e-07 31.0 1.4 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX93439.1 - 1.3e-10 40.9 14.7 1.8e-06 27.6 4.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 ORX93439.1 - 0.0044 17.4 7.4 0.74 10.6 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 ORX93439.1 - 0.033 14.2 6.3 0.25 11.5 0.3 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PP-binding PF00550.25 ORX93440.1 - 8.9e-13 48.4 0.1 1.2e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORX93440.1 - 5.4e-06 26.6 0.3 8.1e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 ORX93440.1 - 0.097 13.1 0.4 0.14 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HAMP PF00672.25 ORX93440.1 - 0.13 12.6 0.3 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 HAMP domain IFRD PF05004.13 ORX93441.1 - 1.4e-65 221.4 12.0 1.6e-65 221.3 11.2 1.5 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 ORX93441.1 - 0.0015 18.6 2.2 0.0033 17.5 2.2 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF374 PF04028.13 ORX93441.1 - 0.032 13.8 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF374) IFRD_C PF04836.12 ORX93441.1 - 0.044 14.4 0.1 0.044 14.4 0.1 3.5 3 1 0 3 3 3 0 Interferon-related protein conserved region HEAT PF02985.22 ORX93441.1 - 0.069 13.4 0.2 43 4.7 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat S1 PF00575.23 ORX93442.1 - 2.1e-72 239.4 44.7 5.3e-16 58.7 1.8 12.9 13 0 0 13 13 13 10 S1 RNA binding domain Suf PF05843.14 ORX93442.1 - 5.3e-08 33.2 0.5 5.3e-08 33.2 0.5 4.1 3 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 ORX93442.1 - 1e-06 29.2 0.8 0.21 12.1 0.1 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 ORX93442.1 - 5.9e-05 22.9 2.0 0.3 11.1 0.2 5.3 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 ORX93442.1 - 0.0002 21.9 0.1 0.28 12.1 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX93442.1 - 0.0032 17.6 0.4 1.2 9.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORX93442.1 - 0.0032 17.7 0.3 1.3 9.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORX93442.1 - 0.0065 17.1 0.1 0.035 14.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX93442.1 - 0.012 15.9 0.8 0.61 10.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORX93442.1 - 0.034 13.4 2.6 6.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX93442.1 - 0.11 12.7 0.7 0.71 10.1 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat NRDE-2 PF08424.10 ORX93442.1 - 0.11 11.6 7.1 0.048 12.8 0.8 3.0 1 1 2 3 3 3 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 ORX93442.1 - 0.18 11.7 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX93442.1 - 0.26 12.0 0.8 84 4.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Trehalase PF01204.18 ORX93443.1 - 4.4e-176 586.7 0.0 5.3e-176 586.4 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 ORX93443.1 - 1.4e-13 50.2 1.2 1.4e-13 50.2 1.2 1.8 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain Mito_carr PF00153.27 ORX93444.1 - 2e-65 216.7 3.0 1e-20 73.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CRCB PF02537.15 ORX93445.1 - 4.8e-32 110.1 18.7 3.2e-19 69.0 5.4 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF21 PF01595.20 ORX93445.1 - 0.17 11.6 4.7 0.23 11.2 3.8 1.8 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF3759 PF12585.8 ORX93446.1 - 6.7e-35 119.0 7.9 9.7e-35 118.5 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) KH_1 PF00013.29 ORX93447.1 - 1.1e-48 162.9 12.1 3.4e-19 68.4 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX93447.1 - 5.8e-17 61.3 5.6 9.3e-05 22.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX93447.1 - 5.6e-08 32.5 1.4 0.065 13.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORX93447.1 - 8.5e-05 22.6 7.2 0.13 12.3 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 ORX93447.1 - 0.0036 17.3 0.0 0.084 12.9 0.0 2.5 2 0 0 2 2 2 1 KH-like RNA-binding domain PRiA4_ORF3 PF07929.11 ORX93448.1 - 1.1e-05 25.2 0.1 1.9e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein NAD_binding_10 PF13460.6 ORX93449.1 - 5.6e-08 32.9 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ORX93449.1 - 0.00018 21.9 0.1 0.00091 19.7 0.0 2.0 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX93449.1 - 0.001 19.2 0.1 0.0017 18.5 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 ORX93449.1 - 0.044 13.2 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORX93449.1 - 0.055 13.5 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 ORX93449.1 - 0.062 13.2 0.1 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 KR domain PGA2 PF07543.12 ORX93450.1 - 1.9e-05 24.6 1.0 2.2e-05 24.5 1.0 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 Cytadhesin_P30 PF07271.11 ORX93450.1 - 0.0016 18.1 0.2 0.0018 17.9 0.2 1.0 1 0 0 1 1 1 1 Cytadhesin P30/P32 MscS_TM PF12794.7 ORX93450.1 - 0.037 12.9 1.9 0.043 12.7 1.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 O-antigen_lig PF13425.6 ORX93450.1 - 0.28 9.9 0.0 0.29 9.9 0.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein 30K_MP_C_Ter PF11330.8 ORX93450.1 - 0.34 10.2 4.4 0.4 10.0 4.4 1.1 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Casc1_N PF15927.5 ORX93450.1 - 1 9.0 15.6 1.4 8.6 15.6 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus FAM178 PF14816.6 ORX93450.1 - 3.4 6.5 8.0 3.9 6.3 8.0 1.0 1 0 0 1 1 1 0 Family of unknown function, FAM178 PET117 PF15786.5 ORX93450.1 - 5.8 7.3 8.6 11 6.3 8.6 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial PCI PF01399.27 ORX93451.1 - 2e-14 54.0 0.1 5.7e-14 52.5 0.1 1.9 1 0 0 1 1 1 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 ORX93451.1 - 0.00087 19.4 0.2 0.003 17.7 0.2 1.9 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 ORX93451.1 - 0.021 14.5 0.3 0.065 12.9 0.3 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 GPS2_interact PF15784.5 ORX93451.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain zf-H2C2_2 PF13465.6 ORX93452.1 - 2.1e-19 69.0 26.8 1.4e-06 28.4 0.6 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX93452.1 - 8.3e-14 51.2 31.1 6.8e-06 26.2 2.0 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93452.1 - 6.7e-07 29.6 29.0 0.0069 17.1 1.7 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX93452.1 - 0.00064 19.4 3.1 0.00064 19.4 3.1 3.2 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORX93452.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX93452.1 - 1.9 9.0 0.1 1.9 9.0 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX93452.1 - 2 8.4 11.2 24 4.9 4.4 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DM PF00751.18 ORX93452.1 - 9.1 6.3 17.9 0.58 10.1 4.1 3.0 2 1 0 2 2 2 0 DM DNA binding domain RRM_2 PF04059.12 ORX93453.1 - 1.1e-44 150.6 0.4 2.7e-44 149.3 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif 2 SNF2_N PF00176.23 ORX93454.1 - 9.1e-71 238.4 0.6 9.1e-71 238.4 0.6 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX93454.1 - 2e-21 76.4 0.2 1.7e-18 67.0 0.0 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 ORX93454.1 - 1.7e-18 66.7 12.5 1.7e-18 66.7 12.5 3.0 2 0 0 2 2 2 1 HSA Bromodomain PF00439.25 ORX93454.1 - 7.6e-18 64.4 0.8 2.9e-17 62.5 0.8 2.1 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 ORX93454.1 - 9.3e-14 51.8 6.8 9.3e-14 51.8 6.8 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ORX93454.1 - 5.9e-10 39.4 6.6 6.8e-10 39.2 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Phage_TAC_8 PF10666.9 ORX93454.1 - 4.7 7.5 8.2 0.32 11.3 0.4 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 DUF3361 PF11841.8 ORX93455.1 - 0.0018 18.2 0.3 0.0041 17.1 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Arm PF00514.23 ORX93455.1 - 0.0053 16.7 0.9 0.13 12.4 0.0 2.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 ORX93455.1 - 0.0057 16.7 0.0 0.012 15.7 0.0 1.5 1 1 1 2 2 2 1 V-ATPase subunit H DUF5578 PF17741.1 ORX93455.1 - 0.0086 15.5 0.0 0.64 9.4 0.1 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5578) MMS22L_C PF14911.6 ORX93455.1 - 0.016 14.3 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Cnd1 PF12717.7 ORX93455.1 - 0.016 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORX93455.1 - 0.022 15.3 0.0 1.7 9.3 0.0 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORX93455.1 - 0.024 13.2 0.1 0.045 12.3 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region Npa1 PF11707.8 ORX93455.1 - 0.078 12.3 0.0 5.8 6.2 0.0 2.1 1 1 1 2 2 2 0 Ribosome 60S biogenesis N-terminal LRR_8 PF13855.6 ORX93456.1 - 1.4e-50 168.9 55.1 3.5e-11 42.7 6.3 6.7 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 ORX93456.1 - 5.1e-43 144.4 61.8 4.6e-07 30.0 1.8 8.0 4 1 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX93456.1 - 2.5e-15 54.7 58.7 0.94 10.3 0.1 13.8 13 1 0 13 13 13 6 Leucine Rich Repeat LRR_9 PF14580.6 ORX93456.1 - 1e-10 41.4 25.4 3.6e-05 23.3 1.2 4.8 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 ORX93456.1 - 1e-05 25.2 57.9 2.5 8.4 0.4 11.9 13 0 0 13 13 13 7 Leucine Rich repeat LRR_5 PF13306.6 ORX93456.1 - 1.6e-05 24.8 0.4 0.036 14.0 0.0 3.4 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 ORX93456.1 - 0.00011 22.2 5.9 14 5.8 0.0 7.2 2 2 7 10 10 10 1 RsmF rRNA methyltransferase first C-terminal domain DUF2385 PF09539.10 ORX93456.1 - 0.021 15.3 0.5 2 9.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) CBAH PF02275.18 ORX93457.1 - 0.017 14.8 0.2 0.024 14.3 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF5082 PF16888.5 ORX93458.1 - 0.047 14.0 0.1 0.096 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Helicase_C PF00271.31 ORX93459.1 - 7.5e-10 39.1 0.0 8.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fe-ADH PF00465.19 ORX93473.1 - 9.4e-71 238.5 0.0 1.1e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORX93473.1 - 2.4e-10 40.6 0.0 7.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 ORX93473.1 - 0.091 11.9 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 3-dehydroquinate synthase RCR PF12273.8 ORX93474.1 - 0.004 17.8 0.8 0.006 17.2 0.8 1.3 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WD40 PF00400.32 ORX93476.1 - 1.8e-41 139.4 16.3 7.4e-08 32.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX93476.1 - 6.5e-18 64.8 0.0 0.00038 20.7 0.1 5.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX93476.1 - 0.00021 21.2 0.0 0.11 12.4 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX93476.1 - 0.00024 20.5 0.0 0.016 14.5 0.0 3.0 2 1 2 4 4 4 2 WD40-like domain Nup160 PF11715.8 ORX93476.1 - 0.012 14.3 0.2 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ret2_MD PF18528.1 ORX93476.1 - 0.079 13.3 0.0 26 5.3 0.0 3.3 3 1 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Cytochrom_D1 PF02239.16 ORX93476.1 - 0.084 11.4 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ureidogly_lyase PF04115.12 ORX93477.1 - 2.2e-48 164.5 0.0 2.7e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase CAF1 PF04857.20 ORX93478.1 - 1.9e-20 73.3 0.0 6.3e-09 35.4 0.0 2.5 1 1 0 2 2 2 2 CAF1 family ribonuclease GTP_EFTU PF00009.27 ORX93479.1 - 2.3e-66 223.0 0.1 3.4e-66 222.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORX93479.1 - 7.5e-33 112.9 0.0 2.2e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORX93479.1 - 8.1e-22 77.1 0.0 3e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORX93479.1 - 9.8e-14 51.2 0.0 2.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ORX93479.1 - 1.9e-12 47.4 0.0 4.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX93479.1 - 2.1e-06 27.8 0.2 4.1e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORX93479.1 - 0.14 11.9 0.1 0.78 9.5 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_trans_NIPA PF05653.14 ORX93480.1 - 1e-106 356.3 15.9 1.3e-106 356.1 15.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORX93480.1 - 2.8e-05 24.3 6.3 2.8e-05 24.3 6.3 3.4 3 1 0 3 3 3 1 EamA-like transporter family DUF5510 PF17629.2 ORX93480.1 - 0.41 10.6 4.1 0.18 11.7 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5510) DUF2937 PF11157.8 ORX93480.1 - 0.53 10.0 2.2 5.3 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Acetyltransf_5 PF13444.6 ORX93482.1 - 1.3e-07 32.2 0.0 2.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX93482.1 - 1.6e-05 24.8 0.0 0.00022 21.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORX93482.1 - 3e-05 24.1 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX93482.1 - 7.4e-05 23.0 0.0 0.00012 22.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF726 PF05277.12 ORX93494.1 - 4.6e-90 302.0 0.0 5.1e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LCAT PF02450.15 ORX93494.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Glyco_hydro_31 PF01055.26 ORX93495.1 - 1.9e-168 561.2 5.6 1.9e-168 561.2 5.6 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORX93495.1 - 7.3e-35 119.7 0.2 1.4e-34 118.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 ORX93495.1 - 2.1e-21 75.5 26.9 7.7e-12 44.9 8.3 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 ORX93495.1 - 1e-11 44.9 1.2 9.7e-11 41.8 0.0 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like GHL15 PF14885.6 ORX93495.1 - 0.045 13.7 0.3 0.079 12.9 0.3 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 RNA_pol_Rpb2_6 PF00562.28 ORX93496.1 - 7.5e-121 403.8 0.5 7.9e-120 400.5 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORX93496.1 - 7.4e-64 215.0 0.1 1e-63 214.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ORX93496.1 - 1.1e-44 152.3 0.1 6.8e-44 149.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORX93496.1 - 4.5e-31 107.1 0.1 9.9e-31 106.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ORX93496.1 - 2.9e-26 91.4 0.1 6.8e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 ORX93496.1 - 7.1e-22 77.5 0.2 2.7e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 ORX93496.1 - 9.9e-16 58.1 1.6 2.4e-15 56.8 1.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MTS PF05175.14 ORX93497.1 - 1.5e-11 44.2 0.0 2.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX93497.1 - 8.1e-07 28.7 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORX93497.1 - 1.6e-05 24.8 0.1 2.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ORX93497.1 - 6.1e-05 22.8 0.0 0.00047 19.9 0.0 1.9 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 ORX93497.1 - 6.6e-05 23.5 0.0 0.00016 22.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORX93497.1 - 0.00071 19.3 0.0 0.00089 18.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 ORX93497.1 - 0.0029 18.3 0.0 0.0061 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 ORX93497.1 - 0.0054 16.0 0.0 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PCMT PF01135.19 ORX93497.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 ORX93497.1 - 0.025 14.9 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF43 PF01861.16 ORX93497.1 - 0.03 13.5 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_15 PF09445.10 ORX93497.1 - 0.046 13.3 0.0 0.084 12.4 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 ORX93497.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORX93497.1 - 0.097 13.3 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ORX93497.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Chitin_synth_2 PF03142.15 ORX93498.1 - 7.3e-238 790.4 1.2 9.9e-238 790.0 1.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORX93498.1 - 2.9e-149 498.4 0.1 3.9e-149 498.0 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORX93498.1 - 7.3e-17 61.0 0.4 3.4e-16 58.9 0.6 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORX93498.1 - 5.9e-12 45.9 0.4 1.8e-11 44.3 0.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX93498.1 - 1.6e-11 44.5 0.0 1e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORX93498.1 - 6.1e-11 42.3 1.3 6.1e-07 29.5 0.1 4.0 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORX93498.1 - 0.00031 20.6 0.0 0.37 10.6 0.0 3.4 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX93498.1 - 0.094 12.2 0.1 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 TTR-52 PF01060.23 ORX93498.1 - 0.13 13.0 0.0 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 Transthyretin-like family Ribosomal_L19e PF01280.20 ORX93499.1 - 2.2e-64 215.9 9.6 2.2e-64 215.9 9.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Epimerase PF01370.21 ORX93500.1 - 3.6e-55 187.0 0.0 5.2e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX93500.1 - 7.2e-15 55.2 0.1 2e-14 53.8 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORX93500.1 - 6.5e-06 25.5 0.1 0.00011 21.4 0.1 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORX93500.1 - 3.6e-05 23.0 0.0 7.7e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX93500.1 - 0.0097 14.9 0.0 0.024 13.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_S19 PF00203.21 ORX93502.1 - 8e-28 96.2 0.0 9.1e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TRAPPC9-Trs120 PF08626.11 ORX93503.1 - 1.2e-239 798.1 0.2 2.3e-239 797.1 0.2 1.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ribosomal_S13 PF00416.22 ORX93504.1 - 2.2e-56 189.8 2.5 2.5e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORX93504.1 - 0.0058 15.4 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 ORX93504.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP28 PF10252.9 ORX93504.1 - 0.12 12.8 0.4 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 HTH_ABP1_N PF18107.1 ORX93505.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain bZIP_1 PF00170.21 ORX93506.1 - 6.8e-08 32.5 16.9 1.3e-07 31.6 16.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX93506.1 - 0.00014 21.8 16.8 0.00027 21.0 14.3 2.2 1 1 1 2 2 2 1 Basic region leucine zipper YabA PF06156.13 ORX93506.1 - 0.00017 22.2 3.0 0.00032 21.3 3.0 1.4 1 0 0 1 1 1 1 Initiation control protein YabA Cep57_CLD_2 PF14197.6 ORX93506.1 - 0.0021 18.1 6.6 0.0055 16.8 6.6 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 SOGA PF11365.8 ORX93506.1 - 0.0021 19.1 2.2 0.0052 17.9 2.2 1.7 1 0 0 1 1 1 1 Protein SOGA ERM PF00769.19 ORX93506.1 - 0.0026 17.6 6.9 0.0033 17.3 6.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fez1 PF06818.15 ORX93506.1 - 0.0041 17.6 6.4 0.0056 17.2 6.4 1.2 1 0 0 1 1 1 1 Fez1 bZIP_Maf PF03131.17 ORX93506.1 - 0.0095 16.4 11.7 0.016 15.7 11.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor LCD1 PF09798.9 ORX93506.1 - 0.011 14.3 4.8 0.014 14.0 4.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FlxA PF14282.6 ORX93506.1 - 0.017 15.1 4.8 0.026 14.5 4.3 1.6 1 1 0 1 1 1 0 FlxA-like protein Spc7 PF08317.11 ORX93506.1 - 0.024 13.5 5.6 0.034 13.0 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 ORX93506.1 - 0.061 13.4 10.1 0.094 12.8 10.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.11 ORX93506.1 - 0.072 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Herpes_UL6 PF01763.16 ORX93506.1 - 0.074 11.6 1.8 0.093 11.2 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3450 PF11932.8 ORX93506.1 - 0.097 12.0 3.3 0.14 11.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2400 PF09674.10 ORX93506.1 - 0.11 12.4 1.3 0.16 12.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) SlyX PF04102.12 ORX93506.1 - 0.12 13.0 3.6 0.29 11.8 3.6 1.7 1 0 0 1 1 1 0 SlyX DUF641 PF04859.12 ORX93506.1 - 0.18 12.1 5.1 0.31 11.4 5.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF5347 PF17282.2 ORX93506.1 - 0.35 11.2 3.6 0.33 11.3 1.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5347) DUF3584 PF12128.8 ORX93506.1 - 0.41 8.1 9.0 0.52 7.8 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 ORX93506.1 - 0.67 9.3 2.5 0.92 8.8 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 ORX93506.1 - 0.8 9.5 4.9 1.7 8.5 4.9 1.5 1 0 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 ORX93506.1 - 1 9.4 7.4 1.5 8.9 7.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EMP24_GP25L PF01105.24 ORX93506.1 - 1.3 8.9 4.1 2 8.3 4.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CENP-H PF05837.12 ORX93506.1 - 1.6 9.1 8.3 2.2 8.8 7.7 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CCDC-167 PF15188.6 ORX93506.1 - 2 8.8 8.2 3.6 8.0 7.4 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.19 ORX93506.1 - 2.2 6.1 4.5 2.7 5.8 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 ORX93506.1 - 2.4 8.7 10.7 5 7.7 10.7 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region E1-E2_ATPase PF00122.20 ORX93507.1 - 2e-28 99.1 0.0 6.3e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORX93507.1 - 1.2e-07 32.2 1.3 0.009 16.3 0.6 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX93507.1 - 0.0043 17.1 0.0 0.081 13.0 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX93507.1 - 0.016 14.9 0.0 0.016 14.9 0.0 2.9 4 0 0 4 4 4 0 Cation transporter/ATPase, N-terminus S6PP PF05116.13 ORX93507.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Glyco_hydro_46 PF01374.18 ORX93508.1 - 3.1e-32 111.9 0.0 3.4e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 FKBP_C PF00254.28 ORX93509.1 - 7.4e-35 119.1 0.0 8.6e-35 119.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3421 PF11901.8 ORX93510.1 - 1.1e-36 125.3 2.0 1.7e-19 69.9 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DHHC PF01529.20 ORX93511.1 - 1.1e-29 103.2 12.8 1.3e-29 102.9 12.8 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase Synaptobrevin PF00957.21 ORX93511.1 - 0.74 9.6 1.8 1 9.2 1.8 1.1 1 0 0 1 1 1 0 Synaptobrevin RhoGEF PF00621.20 ORX93523.1 - 3.1e-39 135.1 6.9 4.7e-39 134.5 6.9 1.3 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 ORX93523.1 - 0.023 14.6 2.3 0.12 12.4 0.0 2.7 3 0 0 3 3 3 0 PH domain zf-C2H2 PF00096.26 ORX93524.1 - 7.6e-12 45.0 11.1 1.4e-05 25.3 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX93524.1 - 1.3e-11 44.4 15.9 2.7e-07 30.7 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX93524.1 - 4.5e-05 23.9 8.6 0.028 15.2 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX93524.1 - 0.017 15.4 5.4 0.02 15.1 1.3 2.6 2 1 0 2 2 2 0 C2H2-type zinc ribbon Zn-C2H2_12 PF18112.1 ORX93524.1 - 0.088 13.3 1.5 1 9.9 0.5 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 ORX93524.1 - 0.12 12.1 0.4 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 ORX93524.1 - 6 6.7 12.8 8.7 6.2 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORX93524.1 - 9.4 6.7 8.2 3.7 8.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PCI PF01399.27 ORX93525.1 - 1.1e-10 42.0 0.4 3.8e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 ORX93525.1 - 0.0027 17.2 1.5 0.0068 16.0 1.5 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix CEP209_CC5 PF16574.5 ORX93525.1 - 0.069 13.3 0.0 0.28 11.4 0.0 2.0 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 FA_hydroxylase PF04116.13 ORX93526.1 - 1.9e-25 89.7 24.7 4.4e-25 88.6 21.0 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily SE PF08491.10 ORX93527.1 - 2e-105 351.8 0.0 3.1e-105 351.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ORX93527.1 - 2.5e-13 50.0 0.0 7.2e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX93527.1 - 4.4e-06 26.5 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX93527.1 - 1.5e-05 25.1 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX93527.1 - 1.9e-05 24.0 0.2 0.0026 16.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ORX93527.1 - 0.00019 20.6 0.1 0.21 10.6 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein GDI PF00996.18 ORX93527.1 - 0.00064 18.4 0.1 0.0016 17.0 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox PF00070.27 ORX93527.1 - 0.0053 17.3 1.5 0.043 14.4 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORX93527.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ORX93527.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ORX93527.1 - 0.013 15.7 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 ORX93527.1 - 0.014 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX93527.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 ORX93527.1 - 0.021 13.6 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 ORX93527.1 - 0.042 12.7 0.4 3.4 6.4 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.7 ORX93527.1 - 0.045 13.1 0.2 0.069 12.5 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 ORX93527.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 ORX93527.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CDP-OH_P_transf PF01066.21 ORX93528.1 - 5.6e-13 49.5 0.8 5.6e-13 49.5 0.8 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase 7TMR-DISM_7TM PF07695.11 ORX93528.1 - 0.053 13.4 4.7 0.086 12.7 4.7 1.4 1 0 0 1 1 1 0 7TM diverse intracellular signalling Macro PF01661.21 ORX93529.1 - 5.2e-39 132.9 0.1 7e-39 132.5 0.1 1.2 1 0 0 1 1 1 1 Macro domain PH PF00169.29 ORX93530.1 - 0.0015 19.0 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF5098 PF17023.5 ORX93530.1 - 0.011 14.7 1.2 0.019 14.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) FA_hydroxylase PF04116.13 ORX93531.1 - 9.9e-25 87.4 15.9 9.9e-25 87.4 15.9 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATA PF00320.27 ORX93533.1 - 2.8e-17 62.0 6.1 5.1e-17 61.2 6.1 1.5 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 ORX93533.1 - 0.032 14.3 0.5 0.062 13.4 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 ORX93533.1 - 0.06 13.5 1.4 0.081 13.1 1.0 1.4 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2_3 PF13878.6 ORX93533.1 - 0.11 12.3 1.5 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-AN1 PF01428.16 ORX93534.1 - 2.3e-10 40.5 9.2 3.4e-10 39.9 9.2 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger FKBP_C PF00254.28 ORX93535.1 - 8.1e-30 103.0 0.0 2.5e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 ORX93535.1 - 3.8e-26 91.7 0.0 3.8e-26 91.7 0.0 2.9 2 1 0 2 2 1 1 Nucleoplasmin-like domain YL1 PF05764.13 ORX93535.1 - 6.7e-05 23.1 28.8 9.4e-05 22.6 28.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Bcl-2_BAD PF10514.9 ORX93535.1 - 0.7 10.3 12.1 1.1 9.7 12.1 1.3 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Asp-B-Hydro_N PF05279.11 ORX93535.1 - 1 9.4 26.8 1.3 9.1 26.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SDA1 PF05285.12 ORX93535.1 - 1.7 8.0 31.3 2.9 7.2 31.3 1.3 1 0 0 1 1 1 0 SDA1 Red1 PF07964.11 ORX93535.1 - 1.9 6.7 19.7 2.3 6.3 19.7 1.0 1 0 0 1 1 1 0 Rec10 / Red1 GAGA_bind PF06217.12 ORX93535.1 - 2.5 8.3 11.7 3.7 7.7 11.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Mitofilin PF09731.9 ORX93535.1 - 2.8 6.7 28.2 3.6 6.3 28.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4045 PF13254.6 ORX93535.1 - 3 7.4 20.2 3.9 7.0 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 ORX93535.1 - 3.2 6.4 14.5 4.2 6.0 14.5 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 ORX93535.1 - 3.2 5.8 29.1 4.6 5.3 29.1 1.2 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 ORX93535.1 - 4.1 6.4 15.3 5.2 6.1 15.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Neur_chan_memb PF02932.16 ORX93535.1 - 4.2 7.4 6.7 5.9 6.9 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.6 ORX93535.1 - 4.5 7.4 12.4 6.9 6.8 12.4 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SAPS PF04499.15 ORX93535.1 - 5.4 5.7 15.0 7.4 5.2 15.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 ORX93535.1 - 6.6 6.0 35.8 9.5 5.5 35.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 ORX93535.1 - 9.1 4.4 23.7 12 4.0 23.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 ORX93535.1 - 9.4 3.2 11.4 12 2.9 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lactamase_B_4 PF13691.6 ORX93536.1 - 2.4e-20 71.9 0.1 5.6e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ORX93536.1 - 3.3e-12 46.3 0.2 8.5e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORX93536.1 - 0.0042 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Caf4 PF11615.8 ORX93536.1 - 0.0044 16.9 0.0 0.38 10.7 0.0 3.5 4 0 0 4 4 4 1 CCR4-associated factor 4 Ribosomal_L39 PF00832.20 ORX93537.1 - 7.5e-23 79.9 9.7 8.5e-23 79.7 9.7 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Putative_PNPOx PF01243.20 ORX93538.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Mito_carr PF00153.27 ORX93539.1 - 1.2e-64 214.2 5.9 5e-22 77.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 ORX93540.1 - 1.3e-51 175.5 0.9 1.4e-51 175.4 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93540.1 - 1e-38 133.1 0.2 1.2e-38 132.9 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX93540.1 - 0.00039 19.8 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX93540.1 - 0.00084 18.7 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_22 PF03901.17 ORX93541.1 - 2.6e-08 33.5 1.0 3.2e-08 33.3 1.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family T4BSS_DotH_IcmK PF12293.8 ORX93541.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion HECT PF00632.25 ORX93542.1 - 1.4e-86 290.7 0.0 1.7e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Thymopoietin PF08198.11 ORX93542.1 - 0.092 12.4 0.3 0.19 11.3 0.3 1.5 1 0 0 1 1 1 0 Thymopoietin protein PAS PF00989.25 ORX93543.1 - 1.8e-06 27.9 0.0 0.078 13.0 0.0 2.5 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 ORX93543.1 - 4.4e-05 23.7 0.0 0.2 11.9 0.0 2.4 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX93543.1 - 7.1e-05 23.0 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORX93543.1 - 0.0023 18.1 0.0 0.067 13.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain Peroxidase_2 PF01328.17 ORX93544.1 - 5.2e-44 151.0 0.0 5.7e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Abhydrolase_1 PF00561.20 ORX93554.1 - 2.1e-16 60.4 0.0 4.9e-16 59.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX93554.1 - 2.4e-13 51.2 0.0 3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX93554.1 - 1.1e-12 47.8 0.0 3.3e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORX93554.1 - 0.00017 21.6 0.1 0.0039 17.1 0.1 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 ORX93554.1 - 0.00089 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 ORX93554.1 - 0.0016 18.3 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORX93554.1 - 0.0083 15.6 0.0 4.1 6.8 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.13 ORX93554.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 ORX93554.1 - 0.038 13.5 0.1 0.11 11.9 0.1 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 ORX93554.1 - 0.043 13.9 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 ORX93554.1 - 0.085 12.8 0.0 2.6 8.0 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.9 ORX93554.1 - 0.13 11.4 0.7 2.4 7.2 0.3 2.1 1 1 1 2 2 2 0 Abhydrolase domain containing 18 Palm_thioest PF02089.15 ORX93554.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DLH PF01738.18 ORX93554.1 - 0.16 11.5 0.0 13 5.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family zf-RING_2 PF13639.6 ORX93555.1 - 1.2e-13 51.1 10.8 1.6e-13 50.8 10.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORX93555.1 - 1.5e-10 41.2 11.4 1.5e-09 38.0 11.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORX93555.1 - 4.9e-09 35.9 9.5 8.9e-09 35.1 9.5 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX93555.1 - 5.9e-08 32.6 7.0 8.3e-08 32.1 7.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORX93555.1 - 1.3e-07 31.4 10.0 1.7e-07 31.0 10.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX93555.1 - 2.2e-07 30.5 8.7 3.9e-07 29.7 8.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORX93555.1 - 4.8e-05 23.3 7.3 0.00024 21.1 7.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORX93555.1 - 5.6e-05 22.9 9.2 0.00019 21.2 9.2 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX93555.1 - 0.00013 21.9 10.2 0.00056 19.8 10.2 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORX93555.1 - 0.00028 20.7 12.3 0.0064 16.3 12.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORX93555.1 - 0.0078 15.8 9.5 0.013 15.1 9.5 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORX93555.1 - 0.0099 16.0 8.1 0.022 14.9 8.1 1.6 1 1 0 1 1 1 1 RING-variant domain zf-UDP PF14569.6 ORX93555.1 - 0.041 14.0 2.9 0.052 13.7 2.9 1.2 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Nse PF11789.8 ORX93555.1 - 0.077 12.8 4.1 0.094 12.5 4.1 1.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 ORX93555.1 - 0.13 12.4 9.3 0.31 11.3 9.3 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 ORX93555.1 - 0.21 11.4 6.6 2.6 7.9 7.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 ORX93555.1 - 1.1 8.9 9.2 3.7 7.3 9.2 1.8 1 1 0 1 1 1 0 P-11 zinc finger zf-C3H2C3 PF17122.5 ORX93555.1 - 3.6 7.7 10.5 11 6.2 10.5 2.0 1 1 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 ORX93556.1 - 5e-11 42.7 7.1 8e-11 42.1 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORX93556.1 - 1.7e-08 34.0 4.5 4.1e-08 32.8 4.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORX93556.1 - 6.3e-08 32.8 9.0 3.5e-07 30.4 9.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORX93556.1 - 3.5e-07 30.1 4.5 5.5e-07 29.5 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORX93556.1 - 2.1e-05 24.3 5.8 3.6e-05 23.6 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX93556.1 - 2.4e-05 24.1 8.5 3.3e-05 23.7 6.7 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX93556.1 - 3.1e-05 23.9 5.5 7e-05 22.8 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX93556.1 - 0.0014 18.7 4.6 0.0025 17.8 4.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORX93556.1 - 0.002 18.0 5.8 0.0054 16.6 5.5 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORX93556.1 - 0.017 14.7 7.1 0.042 13.5 7.1 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 ORX93556.1 - 0.02 14.7 8.0 0.031 14.1 6.6 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 ORX93556.1 - 0.029 14.4 2.2 0.092 12.8 2.2 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 ORX93556.1 - 0.039 14.1 6.6 0.22 11.7 6.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 ORX93556.1 - 0.42 10.8 5.5 0.85 9.8 5.5 1.5 1 1 0 1 1 1 0 RING-variant domain UPF0547 PF10571.9 ORX93556.1 - 0.58 10.3 3.8 12 6.1 0.1 3.3 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 PHD PF00628.29 ORX93556.1 - 0.69 9.9 5.1 1.2 9.0 5.1 1.5 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 ORX93556.1 - 1.1 9.6 5.2 1.8 8.9 5.2 1.3 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 ORX93556.1 - 8.7 6.6 8.7 0.57 10.4 1.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING adh_short PF00106.25 ORX93557.1 - 4.5e-41 140.5 0.1 5.8e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX93557.1 - 1.3e-25 90.3 0.3 1.7e-25 89.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX93557.1 - 4.9e-14 52.6 0.2 7.9e-14 52.0 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORX93557.1 - 0.00051 19.4 0.0 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ORX93557.1 - 0.0016 18.0 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 ORX93557.1 - 0.0046 16.8 0.4 0.0087 15.9 0.4 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 ORX93557.1 - 0.0082 16.0 1.3 0.015 15.2 0.4 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORX93557.1 - 0.014 15.8 0.8 0.025 15.0 0.5 1.7 2 1 0 2 2 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 ORX93557.1 - 0.022 14.9 0.2 0.045 13.9 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ORX93557.1 - 0.029 14.0 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 ORX93557.1 - 0.037 13.2 0.2 0.054 12.6 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_15 PF00723.21 ORX93558.1 - 1.1e-53 182.7 0.1 3.4e-52 177.7 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 MEA1 PF06910.11 ORX93559.1 - 2e-09 38.1 7.8 1e-08 35.8 7.7 2.2 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Roughex PF06020.11 ORX93559.1 - 0.077 12.1 0.4 0.093 11.8 0.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein AAA_12 PF13087.6 ORX93560.1 - 2.3e-43 148.1 0.1 5.9e-43 146.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORX93560.1 - 5.6e-29 101.7 0.2 4.1e-20 72.7 0.0 2.9 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 ORX93560.1 - 6.5e-09 35.9 0.0 0.0068 16.2 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2439 PF10382.9 ORX93560.1 - 5.7e-07 29.8 6.8 4.8e-06 26.8 1.6 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2439) AAA_19 PF13245.6 ORX93560.1 - 7.4e-05 23.1 0.0 0.00045 20.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX93560.1 - 0.0076 16.0 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 ORX93560.1 - 0.0087 15.9 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Ribosomal_L4 PF00573.22 ORX93561.1 - 3e-61 206.5 1.3 3.4e-61 206.3 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family AstE_AspA PF04952.14 ORX93562.1 - 7.4e-47 159.8 0.0 9.6e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SPX PF03105.19 ORX93562.1 - 3.1e-19 70.1 9.3 4.1e-07 30.3 2.5 3.1 2 1 1 3 3 3 3 SPX domain DUF4375 PF14300.6 ORX93562.1 - 0.096 13.0 3.5 0.16 12.3 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) NTF2 PF02136.20 ORX93562.1 - 0.17 12.4 0.7 2 9.0 0.1 2.3 1 1 1 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Peptidase_M24 PF00557.24 ORX93563.1 - 4.8e-09 36.2 0.0 6.3e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Ribosom_S12_S23 PF00164.25 ORX93565.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 tRNA-synt_1g PF09334.11 ORX93566.1 - 2.1e-103 346.1 0.0 4.5e-102 341.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORX93566.1 - 5.8e-25 87.6 4.3 2.4e-12 45.9 1.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ORX93566.1 - 4.7e-13 49.1 0.0 8.3e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Rpr2 PF04032.16 ORX93567.1 - 0.0031 17.8 0.2 0.0061 16.8 0.2 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CCHC PF00098.23 ORX93567.1 - 0.0036 17.3 3.7 0.008 16.2 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle HTH_23 PF13384.6 ORX93567.1 - 0.047 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_50 PF18024.1 ORX93567.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 ORX93567.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HypA PF01155.19 ORX93567.1 - 1 9.4 3.1 35 4.4 0.0 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EamA PF00892.20 ORX93568.1 - 2.8e-27 95.6 33.5 3e-14 53.4 10.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORX93568.1 - 8.1e-05 21.9 0.3 0.00013 21.2 0.3 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 ORX93568.1 - 0.00019 20.8 5.0 0.066 12.4 0.7 3.0 1 1 1 3 3 3 2 Purine nucleobase transmembrane transport TPT PF03151.16 ORX93568.1 - 0.19 11.0 6.3 0.19 11.0 0.7 2.2 1 1 1 2 2 2 0 Triose-phosphate Transporter family Phage_holin_5_2 PF16079.5 ORX93568.1 - 8.1 6.9 7.4 0.47 10.8 0.2 2.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF5586 PF17824.1 ORX93569.1 - 0.089 11.9 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DUF5582 PF17819.1 ORX93569.1 - 0.12 12.9 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5582) cNMP_binding PF00027.29 ORX93570.1 - 9.4e-42 141.0 0.1 1.2e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GerPB PF10803.8 ORX93570.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Spore germination GerPB WD40 PF00400.32 ORX93571.1 - 8.7e-18 64.4 12.1 0.00047 20.9 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 ORX93571.1 - 1.4e-05 23.8 1.9 0.014 13.9 0.0 3.4 3 1 1 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 ORX93571.1 - 0.0067 16.7 0.0 2.5 8.5 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MIP PF00230.20 ORX93572.1 - 1e-58 198.7 8.8 1.3e-58 198.4 8.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Transgly_assoc PF04226.13 ORX93572.1 - 0.01 16.1 1.5 2.2 8.6 0.1 3.1 2 0 0 2 2 2 0 Transglycosylase associated protein Ribosomal_S13 PF00416.22 ORX93573.1 - 2.2e-56 189.8 2.5 2.5e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORX93573.1 - 0.0058 15.4 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 ORX93573.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP28 PF10252.9 ORX93573.1 - 0.12 12.8 0.4 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DSHCT PF08148.12 ORX93574.1 - 2.6e-51 173.5 0.2 5.3e-51 172.5 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 ORX93574.1 - 1.3e-35 122.2 0.0 2.7e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 ORX93574.1 - 6e-25 88.7 2.3 1e-24 87.9 2.3 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 ORX93574.1 - 5.7e-18 65.3 0.0 1.1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX93574.1 - 1.6e-06 28.4 0.0 7.1e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX93574.1 - 9.4e-06 25.7 0.0 2.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 ORX93574.1 - 0.019 14.1 0.2 0.038 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DUF2370 PF10176.9 ORX93575.1 - 0.001 18.8 0.2 0.0018 18.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF4131 PF13567.6 ORX93575.1 - 0.12 12.0 0.4 0.14 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3290 PF11694.8 ORX93575.1 - 1.2 9.1 4.1 1.7 8.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) TcA_TcB_BD PF18276.1 ORX93576.1 - 0.052 12.6 0.0 0.062 12.4 0.0 1.0 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain ToxS PF17323.2 ORX93576.1 - 0.085 12.5 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS HbrB PF08539.11 ORX93589.1 - 1.2e-42 145.8 1.4 3.7e-40 137.7 1.4 2.4 1 1 0 1 1 1 1 HbrB-like Cullin PF00888.22 ORX93589.1 - 0.00015 20.6 0.0 0.00019 20.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family Terpene_synth PF01397.21 ORX93589.1 - 0.035 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain PelD_GGDEF PF16963.5 ORX93589.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 PelD GGDEF domain FAM75 PF14650.6 ORX93589.1 - 3.7 7.0 14.3 5.3 6.5 14.3 1.2 1 0 0 1 1 1 0 FAM75 family zf-C2H2 PF00096.26 ORX93591.1 - 1.5e-24 85.0 24.3 4e-06 27.0 1.6 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX93591.1 - 2.2e-23 81.6 26.5 4.7e-07 29.9 0.7 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX93591.1 - 1.6e-13 50.2 21.7 0.0038 17.9 0.8 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX93591.1 - 0.0002 21.6 7.8 0.14 12.5 3.3 2.8 1 1 2 3 3 3 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORX93591.1 - 0.0013 19.4 9.7 1.3 9.7 0.2 4.0 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX93591.1 - 0.0063 16.8 5.8 8.4 6.8 0.6 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX93591.1 - 0.031 15.0 9.0 0.48 11.2 0.3 3.1 1 1 3 4 4 4 0 TRAF-type zinc finger zf-C2H2_6 PF13912.6 ORX93591.1 - 0.099 12.7 0.2 0.099 12.7 0.2 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 ORX93591.1 - 1.8 9.1 7.2 5 7.7 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 ORX93591.1 - 3.3 7.8 10.3 0.69 9.9 0.3 2.9 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger BCAS3 PF12490.8 ORX93592.1 - 4.4e-06 26.4 0.4 0.0035 16.9 0.1 2.3 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 3 WD40 PF00400.32 ORX93592.1 - 0.00016 22.4 0.3 0.47 11.4 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX93592.1 - 0.12 12.6 0.0 14 6.1 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Herpes_gE PF02480.16 ORX93594.1 - 0.036 12.8 0.7 0.061 12.1 0.0 1.6 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E TP6A_N PF04406.14 ORX93595.1 - 6.9e-21 74.0 0.1 7.9e-21 73.8 0.1 1.0 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RalF_SCD PF18248.1 ORX93595.1 - 0.099 12.6 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain Pyr_redox_2 PF07992.14 ORX93596.1 - 3.1e-48 164.5 1.1 5.5e-47 160.4 1.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX93596.1 - 6.7e-32 110.0 0.1 1.3e-31 109.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORX93596.1 - 3.1e-10 40.5 10.1 4.4e-09 36.8 2.0 3.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX93596.1 - 4.6e-05 22.3 1.9 0.0048 15.7 1.6 2.9 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 ORX93596.1 - 9.5e-05 21.9 1.0 0.00017 21.1 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORX93596.1 - 0.00021 20.6 0.1 0.0017 17.6 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ORX93596.1 - 0.00058 19.1 2.9 0.0013 17.9 1.6 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ORX93596.1 - 0.00062 19.2 2.1 0.014 14.8 0.1 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORX93596.1 - 0.0013 18.1 2.6 0.34 10.2 0.9 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORX93596.1 - 0.0026 17.1 6.1 0.82 8.9 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORX93596.1 - 0.0036 16.4 5.9 0.0041 16.3 3.9 2.0 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORX93596.1 - 0.04 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ORX93596.1 - 0.074 13.5 0.7 2.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORX93596.1 - 0.33 11.2 11.6 0.069 13.4 6.2 2.6 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ORX93596.1 - 0.36 10.7 4.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 ORX93596.1 - 0.67 9.5 14.9 0.35 10.4 5.4 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase ATP19 PF11022.8 ORX93597.1 - 4e-19 68.7 0.1 4.7e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Cornichon PF03311.14 ORX93598.1 - 6.5e-49 165.3 12.4 7.4e-49 165.1 12.4 1.0 1 0 0 1 1 1 1 Cornichon protein Ni_hydr_CYTB PF01292.20 ORX93598.1 - 0.27 10.8 3.2 0.41 10.2 3.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TIM21 PF08294.11 ORX93598.1 - 1.2 9.0 4.6 0.19 11.6 0.6 1.6 2 0 0 2 2 2 0 TIM21 LapA_dom PF06305.11 ORX93598.1 - 1.9 8.4 5.9 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Oleosin PF01277.17 ORX93598.1 - 5.4 6.8 7.3 16 5.3 0.2 2.2 2 0 0 2 2 2 0 Oleosin Ribosomal_L27A PF00828.19 ORX93599.1 - 3.7e-22 79.4 0.1 5.5e-22 78.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A APG9 PF04109.16 ORX93600.1 - 2e-209 696.6 19.2 2.4e-209 696.3 19.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Nramp PF01566.18 ORX93600.1 - 0.49 9.3 3.8 1.6 7.6 1.2 2.2 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein Ribophorin_II PF05817.14 ORX93601.1 - 1.3e-57 195.8 0.0 1.5e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Trs65 PF12735.7 ORX93601.1 - 0.11 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 YiiD_C PF09500.10 ORX93601.1 - 2.5 7.9 4.8 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF1712 PF08217.11 ORX93602.1 - 3.8e-44 151.2 6.8 6.6e-42 143.8 1.9 2.3 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) CutA1 PF03091.15 ORX93602.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Tudor-knot PF11717.8 ORX93602.1 - 1.9 8.4 4.9 0.56 10.1 0.9 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain RUN PF02759.19 ORX93603.1 - 2.7e-18 66.2 0.4 1e-17 64.4 0.0 2.1 2 0 0 2 2 2 1 RUN domain FYVE PF01363.21 ORX93603.1 - 3.5e-17 62.3 6.7 8.9e-17 61.0 6.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger LXG PF04740.12 ORX93603.1 - 0.00046 20.0 1.1 0.0014 18.4 0.2 2.1 1 1 1 2 2 2 1 LXG domain of WXG superfamily TACC_C PF05010.14 ORX93603.1 - 0.00078 19.3 12.5 0.0021 17.9 12.5 1.8 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2935 PF11155.8 ORX93603.1 - 0.0039 17.5 0.0 0.15 12.4 0.0 3.4 2 2 0 2 2 2 1 Domain of unknown function (DUF2935) ATG16 PF08614.11 ORX93603.1 - 0.007 16.6 21.0 0.0072 16.6 17.5 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 ORX93603.1 - 0.0085 15.0 19.5 0.089 11.7 6.9 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein SlyX PF04102.12 ORX93603.1 - 0.018 15.6 0.4 0.018 15.6 0.4 4.1 3 1 0 3 3 3 0 SlyX BLOC1_2 PF10046.9 ORX93603.1 - 0.022 15.0 17.6 0.38 11.1 0.6 4.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Shugoshin_N PF07558.11 ORX93603.1 - 0.09 12.7 4.7 0.063 13.2 1.0 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PHM7_cyt PF14703.6 ORX93603.1 - 0.22 11.8 2.7 0.51 10.6 2.2 2.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Uds1 PF15456.6 ORX93603.1 - 0.58 10.3 13.9 0.062 13.5 5.3 2.9 1 1 2 3 3 3 0 Up-regulated During Septation DZR PF12773.7 ORX93603.1 - 0.6 10.2 5.7 2.9 8.0 5.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon kleA_kleC PF17383.2 ORX93603.1 - 0.72 10.2 7.2 2.4 8.5 0.2 2.8 3 0 0 3 3 2 0 Uncharacterized KorC regulated protein A Filament PF00038.21 ORX93603.1 - 0.83 9.2 18.1 0.2 11.2 1.5 2.3 2 0 0 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 ORX93603.1 - 1.7 9.2 26.6 0.048 14.2 4.4 3.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Sec34 PF04136.15 ORX93603.1 - 1.7 8.5 15.8 0.41 10.5 1.5 3.4 2 1 1 3 3 3 0 Sec34-like family Syntaxin_2 PF14523.6 ORX93603.1 - 2.3 8.6 16.4 0.57 10.6 1.0 3.3 2 1 0 2 2 2 0 Syntaxin-like protein ADIP PF11559.8 ORX93603.1 - 2.4 8.3 26.1 0.24 11.5 5.4 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 ORX93603.1 - 2.5 7.3 22.8 0.97 8.7 3.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 ORX93603.1 - 2.7 7.6 22.1 0.094 12.3 4.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 ORX93603.1 - 3.4 8.2 21.8 3.4 8.2 1.4 3.7 1 1 2 3 3 3 0 Spectrin repeat IFP_35_N PF07334.13 ORX93603.1 - 3.8 7.7 7.1 0.78 9.9 0.3 2.7 3 0 0 3 3 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1043 PF06295.12 ORX93603.1 - 3.8 7.5 12.5 1.8 8.6 6.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) AAA_13 PF13166.6 ORX93603.1 - 5 5.6 12.9 1.4 7.5 2.7 2.3 2 0 0 2 2 2 0 AAA domain KLRAQ PF10205.9 ORX93603.1 - 5.2 7.4 19.4 1.4 9.2 2.1 3.6 2 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein Zn-ribbon_8 PF09723.10 ORX93603.1 - 5.3 7.2 6.7 3 8.0 2.7 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Tropomyosin_1 PF12718.7 ORX93603.1 - 5.7 7.1 26.1 3 8.0 5.8 3.1 2 1 0 2 2 2 0 Tropomyosin like Uso1_p115_C PF04871.13 ORX93603.1 - 6.9 7.0 23.7 1.7 9.0 6.8 2.9 3 0 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 ORX93603.1 - 7.1 6.1 12.4 14 5.1 12.2 1.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit LRRFIP PF09738.9 ORX93603.1 - 7.3 6.0 17.0 58 3.0 17.0 2.2 1 1 0 1 1 1 0 LRRFIP family DASH_Hsk3 PF08227.11 ORX93603.1 - 8.7 6.8 8.1 0.54 10.7 0.6 2.9 3 1 0 3 3 3 0 DASH complex subunit Hsk3 like Mod_r PF07200.13 ORX93603.1 - 9.6 6.3 23.6 1.6 8.9 3.5 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein RPN7 PF10602.9 ORX93604.1 - 1.4e-60 204.0 1.4 1.4e-60 204.0 1.4 2.2 3 0 0 3 3 3 1 26S proteasome subunit RPN7 PCI PF01399.27 ORX93604.1 - 4.2e-18 65.8 1.7 4.2e-18 65.8 1.7 3.1 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 ORX93604.1 - 0.00029 20.7 1.9 0.25 11.6 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX93604.1 - 0.002 17.8 3.0 0.22 11.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF615 PF04751.14 ORX93604.1 - 0.087 12.8 1.7 0.23 11.4 0.4 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF615) HLH PF00010.26 ORX93605.1 - 2.9e-11 43.1 1.6 8.3e-11 41.7 1.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 ORX93605.1 - 0.13 12.5 1.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper RSN1_7TM PF02714.15 ORX93606.1 - 6.8e-74 248.6 23.7 6.8e-74 248.6 23.7 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORX93606.1 - 1.3e-40 138.7 2.3 1.3e-40 138.7 2.3 3.0 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORX93606.1 - 5.4e-34 117.9 0.0 8.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORX93606.1 - 1.5e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RmlD_sub_bind PF04321.17 ORX93607.1 - 7.8e-68 228.6 0.0 9e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ORX93607.1 - 4.7e-27 95.0 0.0 7.4e-27 94.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX93607.1 - 6e-09 35.7 0.4 1.9e-06 27.5 0.1 2.9 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORX93607.1 - 3.1e-05 23.3 0.1 0.012 14.8 0.0 3.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORX93607.1 - 4.2e-05 22.9 0.1 0.026 13.7 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 ORX93607.1 - 0.002 17.2 0.1 0.033 13.2 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORX93607.1 - 0.0095 15.5 0.2 0.077 12.5 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 ORX93607.1 - 0.015 15.2 0.9 0.26 11.2 0.4 2.7 2 2 1 3 3 3 0 KR domain NAD_binding_10 PF13460.6 ORX93607.1 - 0.028 14.3 0.0 0.079 12.8 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 ORX93607.1 - 0.029 13.8 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 ORX93607.1 - 0.046 13.8 0.1 0.096 12.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF5082 PF16888.5 ORX93609.1 - 0.043 14.1 0.4 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) V-ATPase_G PF03179.15 ORX93609.1 - 0.064 13.8 1.2 2.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit COG5 PF10392.9 ORX93609.1 - 0.092 12.9 1.3 0.37 11.0 0.1 2.3 2 1 1 3 3 3 0 Golgi transport complex subunit 5 RGS PF00615.19 ORX93621.1 - 7e-16 58.6 2.6 1e-15 58.0 2.6 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX93621.1 - 0.0069 16.1 17.5 0.027 14.2 17.4 1.8 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Baculo_11_kDa PF06143.11 ORX93621.1 - 0.028 14.0 0.8 0.097 12.3 0.8 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Velvet PF11754.8 ORX93622.1 - 1.1e-71 241.7 4.3 8e-43 147.2 0.0 2.8 2 1 1 3 3 3 2 Velvet factor ubiquitin PF00240.23 ORX93623.1 - 1.5e-34 117.5 0.9 2.1e-34 117.1 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX93623.1 - 2.8e-16 59.1 1.0 4.3e-16 58.5 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 ORX93623.1 - 2.6e-13 49.9 2.4 2.6e-13 49.9 2.4 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 ORX93623.1 - 1.2e-05 25.7 0.2 4.4e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Transp_Tc5_C PF04236.15 ORX93623.1 - 0.002 18.4 1.3 0.0043 17.4 1.3 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain Rad60-SLD_2 PF13881.6 ORX93623.1 - 0.0021 18.2 0.1 0.0044 17.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 ORX93623.1 - 0.0033 17.3 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORX93623.1 - 0.0047 17.2 0.1 0.0069 16.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 ORX93623.1 - 0.01 16.4 0.0 0.015 15.8 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORX93623.1 - 0.016 15.2 1.2 3.5 7.7 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORX93623.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain ChitinaseA_N PF08329.10 ORX93623.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Chitinase A, N-terminal domain IBR PF01485.21 ORX93623.1 - 0.9 9.8 7.9 2.1 8.6 7.8 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 ORX93624.1 - 3.2e-13 49.6 2.6 3.2e-13 49.6 2.6 1.8 1 1 1 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX93624.1 - 0.0018 18.6 4.0 0.0033 17.8 4.0 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain IBR PF01485.21 ORX93624.1 - 1.3 9.3 10.4 1.9 8.7 9.5 1.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 ORX93625.1 - 1.3e-11 44.5 7.8 1.3e-11 44.5 7.8 1.8 1 1 1 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX93625.1 - 0.38 11.1 9.6 0.27 11.6 7.4 1.8 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain KH_1 PF00013.29 ORX93626.1 - 1.1e-47 159.7 10.9 3.5e-18 65.2 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX93626.1 - 1.4e-14 53.6 7.2 4e-05 23.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX93626.1 - 2.3e-05 24.2 4.5 0.093 12.6 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 ORX93626.1 - 0.00051 20.1 8.0 0.063 13.4 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 ORX93626.1 - 0.043 13.8 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 KH-like RNA-binding domain TMEM154 PF15102.6 ORX93628.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 ORX93628.1 - 0.22 11.4 0.1 0.44 10.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Amidohydro_3 PF07969.11 ORX93629.1 - 1.3e-74 252.4 0.0 1.5e-74 252.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORX93629.1 - 1.1e-08 34.8 0.0 8.9e-06 25.2 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Exo_endo_phos PF03372.23 ORX93646.1 - 2.8e-08 33.6 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CAP59_mtransfer PF11735.8 ORX93646.1 - 0.096 12.4 0.1 0.16 11.6 0.1 1.6 1 1 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Mito_carr PF00153.27 ORX93649.1 - 3.8e-28 97.3 4.6 2.1e-12 46.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX93649.1 - 0.00056 19.1 0.1 0.0031 16.7 0.0 2.1 2 0 0 2 2 2 1 Gammaproteobacterial serine protease ATP-synt PF00231.19 ORX93650.1 - 4.9e-75 252.8 9.8 5.5e-75 252.7 9.8 1.0 1 0 0 1 1 1 1 ATP synthase Seryl_tRNA_N PF02403.22 ORX93650.1 - 0.023 14.9 2.5 0.13 12.6 0.0 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ecl1 PF12855.7 ORX93651.1 - 2.4e-11 45.1 9.2 2.8e-11 44.9 9.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins SMN PF06003.12 ORX93651.1 - 0.036 13.3 0.2 0.04 13.2 0.2 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF2116 PF09889.9 ORX93651.1 - 0.06 13.3 0.3 0.081 12.9 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-MYND PF01753.18 ORX93651.1 - 0.065 13.3 2.1 0.065 13.3 2.1 1.9 2 1 0 2 2 2 0 MYND finger Ecl1 PF12855.7 ORX93652.1 - 1.9e-11 45.5 2.3 2.2e-11 45.2 2.3 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 ORX93652.1 - 0.002 18.1 0.2 0.0029 17.5 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) C1_2 PF03107.16 ORX93652.1 - 0.029 14.7 2.0 0.058 13.7 2.0 1.5 1 0 0 1 1 1 0 C1 domain AlaDh_PNT_N PF05222.15 ORX93653.1 - 1.7e-27 96.4 0.0 2.6e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 ORX93653.1 - 9.3e-07 28.3 0.0 5.4e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1752 PF08550.10 ORX93654.1 - 1.6e-11 43.8 2.4 3.1e-11 42.9 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1604 PF07713.13 ORX93655.1 - 2.5e-40 136.2 1.5 6.6e-40 134.8 1.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 ORX93655.1 - 2.2e-07 30.7 0.5 5.2e-07 29.4 0.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORX93655.1 - 0.093 12.8 0.1 0.34 11.0 0.1 2.0 1 0 0 1 1 1 0 G-patch domain Arrestin_C PF02752.22 ORX93656.1 - 2.5e-12 47.4 1.6 1.2e-05 25.8 0.5 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX93656.1 - 2.5e-08 34.1 0.0 1.4e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain G8 PF10162.9 ORX93656.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 G8 domain DPPIV_N PF00930.21 ORX93657.1 - 1.8e-98 329.6 3.3 2.4e-98 329.2 3.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORX93657.1 - 2.9e-47 160.9 0.2 4.5e-47 160.3 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORX93657.1 - 0.0018 18.9 0.0 0.035 14.7 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.12 ORX93657.1 - 0.0046 16.9 7.2 1.8 8.6 0.0 4.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DLH PF01738.18 ORX93657.1 - 0.12 11.9 0.0 0.79 9.2 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family NMT1 PF09084.11 ORX93658.1 - 1.8e-12 47.7 0.0 2.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ORX93658.1 - 4.4e-08 33.1 0.1 8.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 NMT1-like family LysR_substrate PF03466.20 ORX93658.1 - 0.018 14.4 0.0 0.07 12.5 0.0 1.9 1 1 0 1 1 1 0 LysR substrate binding domain DUF4106 PF13388.6 ORX93659.1 - 0.76 9.0 9.4 0.7 9.1 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pet100 PF09803.9 ORX93660.1 - 7.2e-20 71.3 0.1 9.8e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Pet100 Pkinase PF00069.25 ORX93662.1 - 2e-64 217.5 0.0 2.4e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93662.1 - 1.5e-16 60.5 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX93662.1 - 2.7e-08 34.0 0.0 5.2e-06 26.6 0.1 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX93662.1 - 0.009 14.8 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 ORX93662.1 - 0.014 15.0 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 ORX93662.1 - 0.017 14.4 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 ORX93662.1 - 0.077 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 ORX93662.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PQ-loop PF04193.14 ORX93681.1 - 1.2e-17 63.4 15.0 1.5e-09 37.5 2.2 3.1 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 ORX93681.1 - 2.9e-05 24.0 10.3 0.025 14.6 0.7 3.1 2 1 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF3290 PF11694.8 ORX93681.1 - 6.8 6.7 5.4 7.2 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) LIM PF00412.22 ORX93682.1 - 1.3e-23 83.0 11.4 1.3e-13 51.0 3.6 2.0 2 0 0 2 2 2 2 LIM domain P2X_receptor PF00864.19 ORX93683.1 - 1.1e-18 67.5 0.7 2.6e-10 39.9 0.1 2.6 2 1 1 3 3 3 2 ATP P2X receptor Peptidase_M99_m PF17130.4 ORX93684.1 - 0.00016 21.6 0.1 25 4.9 0.0 4.3 4 0 0 4 4 4 4 beta-barrel domain of carboxypeptidase M99 DUF2593 PF10767.9 ORX93684.1 - 0.038 14.0 0.3 38 4.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2593) Peptidase_M99_m PF17130.4 ORX93685.1 - 0.0026 17.7 0.2 28 4.7 0.0 4.1 4 0 0 4 4 4 3 beta-barrel domain of carboxypeptidase M99 Aconitase PF00330.20 ORX93686.1 - 4.2e-153 510.6 0.0 5.3e-153 510.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX93686.1 - 1.6e-43 148.2 0.0 2.8e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TFIIS_M PF07500.14 ORX93689.1 - 2.9e-27 95.3 5.9 3.4e-27 95.2 5.9 1.0 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain KIX_2 PF16987.5 ORX93689.1 - 1.3e-05 25.0 1.1 2.4e-05 24.2 1.1 1.4 1 0 0 1 1 1 1 KIX domain Ammonium_transp PF00909.21 ORX93690.1 - 2.2e-209 695.1 67.4 4.2e-105 351.7 29.7 2.1 2 0 0 2 2 2 2 Ammonium Transporter Family Rieske PF00355.26 ORX93690.1 - 8.1e-08 32.1 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Abhydro_lipase PF04083.16 ORX93690.1 - 0.0012 18.3 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Phage_holin_2_1 PF04971.12 ORX93690.1 - 0.07 13.1 11.8 2.3 8.3 2.2 3.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S Methyltransf_23 PF13489.6 ORX93692.1 - 4.2e-05 23.5 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX93692.1 - 0.00093 19.9 0.0 0.0021 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93692.1 - 0.16 12.7 0.0 0.5 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CHASE PF03924.13 ORX93699.1 - 0.013 15.5 0.1 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 CHASE domain DUF3472 PF11958.8 ORX93700.1 - 1.9e-11 44.8 0.7 3e-11 44.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX93700.1 - 8.4e-08 32.6 13.7 1.9e-07 31.4 13.7 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORX93700.1 - 0.014 15.3 0.2 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) Acetyltransf_8 PF13523.6 ORX93700.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4937 PF16291.5 ORX93700.1 - 0.054 13.7 0.5 0.097 12.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 DUF3472 PF11958.8 ORX93701.1 - 2.3e-11 44.5 0.7 3.6e-11 43.8 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX93701.1 - 8.5e-08 32.6 13.7 1.9e-07 31.4 13.7 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORX93701.1 - 0.014 15.3 0.2 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) Acetyltransf_8 PF13523.6 ORX93701.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4937 PF16291.5 ORX93701.1 - 0.054 13.8 0.5 0.097 12.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 ADH_N PF08240.12 ORX93704.1 - 9.1e-25 86.7 4.8 1.5e-24 86.0 4.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX93704.1 - 8.4e-19 67.8 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX93704.1 - 0.0029 18.7 0.0 0.0062 17.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX93704.1 - 0.025 13.9 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX93704.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.28 ORX93705.1 - 1.4e-16 61.2 2.0 1.7e-16 60.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Phospholip_B PF04916.13 ORX93705.1 - 0.0014 17.3 0.2 0.0023 16.6 0.2 1.3 1 0 0 1 1 1 1 Phospholipase B Sugar_tr PF00083.24 ORX93706.1 - 5e-58 197.1 21.9 5.9e-58 196.8 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX93706.1 - 3.7e-27 95.2 24.9 3.7e-27 95.2 24.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX93706.1 - 1.1e-07 31.6 3.6 2.2e-07 30.5 3.6 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX93706.1 - 9.1e-05 21.2 7.7 9.1e-05 21.2 7.7 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF417 PF04224.12 ORX93706.1 - 0.0015 18.1 0.8 0.044 13.3 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORX93706.1 - 0.34 9.1 11.3 0.25 9.6 5.2 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CHAP PF05257.16 ORX93707.1 - 3.5e-10 40.3 2.1 4.9e-10 39.9 2.1 1.2 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX93708.1 - 1e-08 35.6 0.9 1.6e-08 35.0 0.9 1.2 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX93709.1 - 1e-10 42.1 2.9 1.6e-10 41.4 2.9 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX93710.1 - 2.5e-10 40.8 2.4 3.9e-10 40.2 2.4 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX93711.1 - 1.1e-08 35.5 0.3 1.7e-08 34.9 0.3 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX93712.1 - 1.5e-10 41.5 2.6 2.3e-10 40.9 2.6 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX93713.1 - 8.4e-10 39.1 3.0 1.4e-09 38.4 3.0 1.3 1 0 0 1 1 1 1 CHAP domain GPCR_chapero_1 PF11904.8 ORX93714.1 - 1.5e-09 37.7 0.0 4.9e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 ORX93714.1 - 0.02 15.5 0.1 0.065 13.8 0.1 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX93714.1 - 0.031 14.8 0.5 0.33 11.6 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 ORX93714.1 - 0.039 14.4 0.7 0.17 12.4 0.4 2.2 2 0 0 2 2 2 0 Ankyrin repeat YL1 PF05764.13 ORX93714.1 - 0.09 12.9 0.6 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SSF PF00474.17 ORX93715.1 - 1.4e-11 43.9 32.6 8.9e-11 41.3 32.6 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family zf-H2C2_2 PF13465.6 ORX93720.1 - 9.5e-21 73.2 12.3 1.6e-06 28.3 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX93720.1 - 1.8e-19 69.0 22.0 5.3e-06 26.6 2.3 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93720.1 - 2.3e-08 34.2 19.7 0.003 18.2 1.5 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORX93720.1 - 2.6e-07 31.1 6.6 0.0021 18.6 0.9 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX93720.1 - 0.00016 21.9 3.8 0.038 14.3 1.6 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORX93720.1 - 0.0027 18.0 6.3 1.4 9.4 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX93720.1 - 0.011 16.0 6.1 0.39 11.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 ORX93720.1 - 0.026 15.2 12.8 0.094 13.5 2.1 3.5 2 1 1 3 3 3 0 CHORD zf-C2H2_11 PF16622.5 ORX93720.1 - 0.073 12.8 1.1 0.073 12.8 1.1 3.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-TRAF PF02176.18 ORX93720.1 - 0.76 10.5 8.5 0.38 11.5 1.6 2.7 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORX93720.1 - 1.5 8.9 8.4 27 4.8 1.3 3.6 2 2 1 3 3 3 0 Aberrant zinc-finger 5_nucleotid_C PF02872.18 ORX93721.1 - 1.1e-33 116.7 0.1 2.4e-33 115.6 0.0 1.6 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORX93721.1 - 3.4e-12 47.3 1.3 5.8e-12 46.5 1.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CoA_binding PF02629.19 ORX93721.1 - 0.054 14.2 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain Cytochrom_B561 PF03188.16 ORX93722.1 - 6e-19 68.5 8.3 1e-18 67.8 8.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 UL41A PF17591.2 ORX93722.1 - 7.6 6.7 9.9 6.6 6.9 0.1 2.7 3 0 0 3 3 3 0 Herpesvirus UL41A Ank_2 PF12796.7 ORX93723.1 - 2.8e-11 43.9 1.7 0.00037 21.0 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX93723.1 - 2.4e-07 31.2 0.3 0.0014 19.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX93723.1 - 4e-07 29.8 0.1 0.2 12.3 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORX93723.1 - 5e-07 29.9 1.4 0.014 15.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 ORX93723.1 - 8.2e-05 22.4 0.1 0.0012 18.7 0.1 2.6 1 1 0 1 1 1 1 KilA-N domain DHR10 PF18595.1 ORX93723.1 - 0.0067 16.5 7.1 0.0067 16.5 7.1 2.0 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain Noc2 PF03715.13 ORX93723.1 - 0.024 13.9 2.6 0.037 13.3 2.1 1.6 2 0 0 2 2 2 0 Noc2p family DUF1664 PF07889.12 ORX93723.1 - 0.24 11.4 4.2 0.83 9.7 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 ORX93723.1 - 2.6 7.9 7.2 1.3 8.9 4.3 2.0 2 0 0 2 2 2 0 Sec34-like family FapA PF03961.13 ORX93723.1 - 5.4 5.5 8.1 4.3 5.8 4.0 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A PTH2 PF01981.16 ORX93724.1 - 4.6e-19 68.8 0.1 5.1e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 NST1 PF13945.6 ORX93726.1 - 7.9e-38 130.5 24.8 7.9e-38 130.5 24.8 3.7 3 1 0 3 3 3 1 Salt tolerance down-regulator SUZ-C PF12901.7 ORX93727.1 - 1.6 8.8 11.3 8.9 6.4 4.5 2.8 2 0 0 2 2 2 0 SUZ-C motif RNA_POL_M_15KD PF02150.16 ORX93728.1 - 3.1e-14 52.5 11.0 4.3e-14 52.1 6.6 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 ORX93728.1 - 3.9e-13 49.0 14.9 1.1e-12 47.6 3.6 3.2 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 ORX93728.1 - 4.6e-05 22.7 7.1 0.52 9.8 0.6 3.4 3 0 0 3 3 3 3 zinc-ribbon domain CpXC PF14353.6 ORX93728.1 - 0.00061 19.8 7.3 0.068 13.2 0.6 2.3 2 1 0 2 2 2 2 CpXC protein Lar_restr_allev PF14354.6 ORX93728.1 - 0.054 13.9 1.6 0.054 13.9 1.6 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 ORX93728.1 - 0.066 13.2 11.6 0.067 13.2 2.8 2.5 2 1 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORX93728.1 - 0.27 11.2 9.0 0.67 9.9 2.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.6 ORX93728.1 - 0.94 10.2 0.1 0.94 10.2 0.1 3.5 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 SR1P PF13790.6 ORX93728.1 - 1.5 9.0 11.5 4.1 7.6 0.2 3.5 4 1 0 4 4 4 0 SR1 protein DUF3268 PF11672.8 ORX93728.1 - 1.8 8.9 6.6 3.2 8.1 1.0 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain Zn_Tnp_IS1595 PF12760.7 ORX93728.1 - 2.5 8.1 14.9 1.1 9.3 5.0 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 ORX93728.1 - 5.5 7.2 13.0 2 8.6 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 ORX93728.1 - 8.6 6.5 16.0 4.7 7.3 2.8 3.3 2 2 1 3 3 3 0 Transposase zinc-binding domain HSP20 PF00011.21 ORX93729.1 - 1.8e-14 53.7 0.0 1.7e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORX93729.1 - 7.6e-08 31.8 0.0 1.9e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 ORX93730.1 - 4.7e-15 55.6 0.0 7.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORX93730.1 - 2.9e-09 36.4 0.1 6.3e-09 35.3 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA zf-C2H2 PF00096.26 ORX93731.1 - 6.3e-12 45.3 10.6 1.1e-05 25.6 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX93731.1 - 6.1e-08 32.9 8.7 0.00033 21.3 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX93731.1 - 5.6e-07 29.7 2.5 5.6e-07 29.7 2.5 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX93731.1 - 0.00019 21.7 1.0 0.7 10.4 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX93731.1 - 0.0037 17.5 2.0 0.54 10.6 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX93731.1 - 0.0045 17.2 0.4 1.6 9.0 0.1 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORX93731.1 - 0.0048 16.9 1.1 0.0048 16.9 1.1 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORX93731.1 - 0.0055 17.3 0.4 2.6 8.7 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORX93731.1 - 0.0086 16.2 1.0 0.92 9.6 0.1 2.0 1 1 0 2 2 2 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORX93731.1 - 0.01 15.6 10.7 0.21 11.4 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-TRAF PF02176.18 ORX93731.1 - 0.017 15.8 3.1 0.044 14.5 3.1 1.6 1 1 0 1 1 1 0 TRAF-type zinc finger CHORD PF04968.12 ORX93731.1 - 0.034 14.8 2.0 2.7 8.8 0.3 2.1 1 1 1 2 2 2 0 CHORD ADD_ATRX PF17981.1 ORX93731.1 - 0.044 13.7 1.7 1.1 9.2 0.1 2.0 1 1 1 2 2 2 0 Cysteine Rich ADD domain zf-C2HE PF16278.5 ORX93731.1 - 0.049 14.1 5.1 0.46 11.0 0.8 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Pkinase PF00069.25 ORX93732.1 - 1.9e-49 168.4 0.0 2.9e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93732.1 - 1.7e-30 106.2 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX93732.1 - 2.2e-06 27.2 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORX93732.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX93732.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 ORX93733.1 - 4e-25 88.5 62.5 3.9e-21 75.4 38.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX93733.1 - 0.36 9.6 25.3 2.2 7.1 0.2 3.4 2 2 0 2 2 2 0 Sugar (and other) transporter Syntaxin-18_N PF10496.9 ORX93734.1 - 5.1e-19 68.3 1.3 5.1e-19 68.3 1.3 3.0 3 2 2 5 5 5 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 ORX93734.1 - 0.084 12.9 0.5 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 SNARE domain SET PF00856.28 ORX93735.1 - 1.6e-07 31.9 0.1 1.1e-06 29.1 0.1 2.1 1 1 0 1 1 1 1 SET domain Vps52 PF04129.12 ORX93736.1 - 1e-134 450.1 19.6 1.5e-134 449.6 19.6 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 ORX93736.1 - 5.1e-11 41.7 22.2 3.3e-09 35.7 12.2 2.4 2 1 0 2 2 2 2 Exocyst complex component Sec3 COG2 PF06148.11 ORX93736.1 - 0.0028 17.7 6.1 0.027 14.6 2.4 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 ORX93736.1 - 0.036 14.4 1.4 1 9.8 1.0 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Peptidase_C50 PF03568.17 ORX93736.1 - 0.084 12.0 3.9 0.87 8.6 0.1 2.3 2 0 0 2 2 2 0 Peptidase family C50 DUF1664 PF07889.12 ORX93736.1 - 0.11 12.6 1.6 0.38 10.8 1.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 ORX93736.1 - 0.11 12.0 10.0 0.055 12.9 7.7 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 ORX93736.1 - 0.16 12.0 2.6 1.8 8.6 0.5 2.9 2 0 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 ORX93736.1 - 0.18 11.9 6.9 0.47 10.5 2.8 3.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELO PF01151.18 ORX93737.1 - 2e-60 204.5 26.2 2.4e-60 204.2 26.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L16 PF00252.18 ORX93738.1 - 3.2e-46 156.6 0.1 3.9e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PMP22_Claudin PF00822.20 ORX93739.1 - 0.00076 19.4 2.2 0.0013 18.6 2.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2427 PF10348.9 ORX93739.1 - 0.2 11.5 6.5 0.43 10.4 1.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF2157 PF09925.9 ORX93739.1 - 0.23 11.2 3.0 4.4 7.1 2.6 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) CoxIIa PF08113.11 ORX93739.1 - 6.8 6.6 8.8 0.46 10.4 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family RPA_interact_C PF14768.6 ORX93740.1 - 9.1e-06 26.2 7.4 3.6e-05 24.3 7.4 2.1 1 1 0 1 1 1 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 ORX93740.1 - 0.0054 16.3 8.9 0.0095 15.6 8.9 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal DUF2318 PF10080.9 ORX93740.1 - 0.02 15.0 1.2 0.02 15.0 1.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Cytochrome_C7 PF14522.6 ORX93740.1 - 0.47 10.5 7.0 0.073 13.1 2.8 1.9 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c PHD PF00628.29 ORX93740.1 - 0.81 9.6 9.2 0.36 10.8 2.0 2.5 2 0 0 2 2 2 0 PHD-finger Ephrin_rec_like PF07699.13 ORX93740.1 - 1 9.2 5.1 0.15 11.8 1.1 1.7 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-CCCH PF00642.24 ORX93742.1 - 6.5e-15 54.6 30.8 5.7e-05 22.9 5.1 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX93742.1 - 1.8e-10 40.5 37.1 4.5e-05 23.4 6.0 6.0 5 1 0 5 5 5 4 Zinc finger domain Torus PF16131.5 ORX93742.1 - 1.1e-07 32.5 25.7 0.015 16.0 2.1 5.2 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 ORX93742.1 - 9.1e-05 22.6 18.9 0.00011 22.4 0.8 3.8 1 1 2 3 3 3 2 Zinc-finger containing family zf-C3H1 PF10650.9 ORX93742.1 - 0.045 13.5 16.3 0.61 9.9 0.5 4.7 5 0 0 5 5 5 0 Putative zinc-finger domain CPSF_A PF03178.15 ORX93743.1 - 6.1e-85 285.4 0.1 2.4e-84 283.4 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 ORX93743.1 - 2.2e-41 142.0 0.0 1.7e-40 139.1 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RGS PF00615.19 ORX93744.1 - 1.2e-13 51.3 1.3 1.1e-11 45.1 1.3 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_L7Ae PF01248.26 ORX93745.1 - 6.6e-28 96.3 4.0 8.4e-28 96.0 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CAP_N PF01213.19 ORX93746.1 - 3.1e-65 220.8 2.9 1.8e-64 218.2 2.9 1.8 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ORX93746.1 - 2.3e-19 69.5 4.5 3.6e-19 68.9 4.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 ORX93746.1 - 0.00019 21.1 1.3 0.0004 20.1 1.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C HSR PF03172.13 ORX93746.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 HSR domain zf-C2H2_9 PF16293.5 ORX93746.1 - 0.05 13.5 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) RCDG1 PF15725.5 ORX93746.1 - 0.82 10.1 6.5 0.21 12.0 3.1 1.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein UCH PF00443.29 ORX93747.1 - 3.4e-43 148.0 3.7 4.8e-43 147.5 2.4 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 ORX93747.1 - 4e-21 74.7 0.8 4.3e-11 42.6 0.3 2.8 2 0 0 2 2 2 2 A repeated domain in UCH-protein PUB PF09409.10 ORX93747.1 - 1.6e-06 27.9 0.2 1e-05 25.3 0.1 2.4 3 0 0 3 3 3 1 PUB domain UCH_1 PF13423.6 ORX93747.1 - 3.9e-05 23.4 11.4 0.0019 17.8 0.0 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Laminin_II PF06009.12 ORX93747.1 - 0.027 14.5 0.5 0.073 13.1 0.5 1.7 1 0 0 1 1 1 0 Laminin Domain II Pkinase PF00069.25 ORX93748.1 - 1.7e-70 237.4 0.0 1.9e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93748.1 - 2.3e-35 122.1 0.0 2.8e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX93748.1 - 8.1e-06 25.4 0.1 5.3e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX93748.1 - 1.9e-05 23.8 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX93748.1 - 0.00018 21.5 0.1 0.036 14.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORX93748.1 - 0.0077 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX93748.1 - 0.02 14.5 1.0 0.21 11.2 0.0 2.0 1 1 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 ORX93748.1 - 0.031 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORX93748.1 - 0.044 12.6 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ORX93748.1 - 0.11 12.0 0.1 9.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YTH PF04146.15 ORX93749.1 - 6.3e-42 143.3 0.4 1.4e-41 142.2 0.4 1.5 1 1 0 1 1 1 1 YT521-B-like domain DUF4108 PF13390.6 ORX93749.1 - 0.063 13.2 0.5 0.24 11.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) Polyketide_cyc2 PF10604.9 ORX93750.1 - 2.2e-07 31.3 0.7 2.5e-07 31.1 0.7 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Haem_degrading PF03928.14 ORX93751.1 - 1e-34 119.1 0.0 1.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading Glu-tRNAGln PF02686.15 ORX93752.1 - 1.3e-08 34.9 0.0 1.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit EF-hand_8 PF13833.6 ORX93752.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair TB2_DP1_HVA22 PF03134.19 ORX93753.1 - 1.9e-18 66.2 4.1 3.3e-18 65.4 4.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sugar_tr PF00083.24 ORX93753.1 - 0.0073 15.2 0.1 0.015 14.2 0.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Thioredoxin PF00085.20 ORX93769.1 - 2e-35 120.9 1.6 7e-24 83.8 0.5 3.5 3 1 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 ORX93769.1 - 2.1e-10 40.8 1.0 3.1e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 ORX93769.1 - 2.8e-10 40.6 0.8 3.1e-05 24.4 0.2 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ORX93769.1 - 1.4e-07 31.2 1.8 0.0044 16.4 0.1 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORX93769.1 - 1.7e-07 31.4 2.5 0.005 17.1 0.1 4.3 3 2 1 4 4 4 2 Thioredoxin-like HyaE PF07449.11 ORX93769.1 - 0.00022 21.1 0.0 0.048 13.6 0.0 2.7 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 ORX93769.1 - 0.0019 18.1 0.2 0.0053 16.7 0.1 1.8 2 0 0 2 2 2 1 AhpC/TSA family TraF PF13728.6 ORX93769.1 - 0.0038 17.1 8.6 0.0075 16.1 0.1 3.6 3 2 1 4 4 4 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ORX93769.1 - 0.0043 16.8 0.2 0.2 11.4 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.6 ORX93769.1 - 0.015 15.4 0.2 1 9.5 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 ORX93769.1 - 0.13 12.4 0.1 0.47 10.7 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 ORX93769.1 - 0.15 11.8 0.4 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 Redoxin Cyclin PF08613.11 ORX93770.1 - 2.3e-19 70.3 0.7 2.7e-19 70.1 0.7 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX93770.1 - 3.5e-10 39.7 0.2 4.4e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 ORX93771.1 - 1e-66 225.1 5.8 1e-66 225.1 5.8 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX93771.1 - 1.3e-42 144.5 0.2 8e-42 142.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORX93771.1 - 6.9e-21 74.6 13.6 7.2e-19 68.1 2.1 4.1 4 1 2 6 6 5 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX93771.1 - 6e-12 45.4 4.5 2.2e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX93771.1 - 2e-11 43.9 1.1 2e-11 43.9 1.1 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 ORX93771.1 - 1e-09 38.0 10.6 2.7e-09 36.6 3.1 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORX93771.1 - 6e-09 36.0 2.7 4e-05 23.8 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORX93771.1 - 3.8e-08 32.8 2.7 3.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 ORX93771.1 - 1e-07 31.0 13.3 9.2e-05 21.3 1.2 4.1 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 ORX93771.1 - 1.7e-07 30.7 2.2 1.7e-07 30.7 2.2 3.4 3 1 1 4 4 4 1 FAD binding domain K_oxygenase PF13434.6 ORX93771.1 - 1.8e-06 27.3 0.1 0.0013 17.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ORX93771.1 - 0.00012 21.5 10.6 0.01 15.2 1.0 3.3 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORX93771.1 - 0.00043 19.6 10.5 0.014 14.7 1.0 3.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 ORX93771.1 - 0.00063 19.4 12.7 0.12 11.9 0.3 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ORX93771.1 - 0.075 13.5 1.3 4.1 7.9 0.1 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORX93771.1 - 0.5 9.4 4.8 0.36 9.8 0.4 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 ORX93771.1 - 2.5 7.9 6.5 0.41 10.5 0.6 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-DNL PF05180.12 ORX93772.1 - 4.7e-30 103.3 0.2 6.9e-30 102.8 0.2 1.2 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 ORX93772.1 - 0.024 14.7 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PHD PF00628.29 ORX93772.1 - 0.74 9.8 4.7 16 5.5 3.4 2.4 1 1 1 2 2 2 0 PHD-finger Glyco_hydro_15 PF00723.21 ORX93773.1 - 1.9e-107 359.8 0.0 2.4e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 ORX93773.1 - 2.5e-22 79.2 0.0 6e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Interleukin-like EMT inducer DCB PF16213.5 ORX93773.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 E1-E2_ATPase PF00122.20 ORX93774.1 - 3.2e-50 170.2 9.4 1.8e-49 167.7 1.8 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX93774.1 - 3.8e-32 111.5 2.1 3.8e-32 111.5 2.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX93774.1 - 1.1e-20 73.4 0.0 2.4e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX93774.1 - 2.6e-17 62.3 0.0 8e-17 60.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 ORX93774.1 - 1.1e-16 61.7 0.1 2.9e-15 57.1 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX93774.1 - 0.00034 20.4 1.1 0.0052 16.6 1.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 ORX93774.1 - 0.032 14.1 0.2 0.032 14.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) DUF5418 PF17439.2 ORX93774.1 - 1.4 9.0 6.6 1.2 9.2 1.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5418) Virul_fac_BrkB PF03631.15 ORX93774.1 - 5.4 6.5 10.2 2.9 7.4 0.1 3.2 3 0 0 3 3 3 0 Virulence factor BrkB p450 PF00067.22 ORX93775.1 - 1.2e-69 235.2 0.0 1.6e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP11 PF06644.11 ORX93776.1 - 1.2e-77 261.4 4.0 1.4e-77 261.2 4.0 1.0 1 0 0 1 1 1 1 ATP11 protein U3_assoc_6 PF08640.11 ORX93777.1 - 8.9e-34 115.4 11.8 8.1e-33 112.3 5.4 3.2 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 ORX93777.1 - 8.6e-11 41.7 6.9 0.031 15.1 0.4 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX93777.1 - 3.2e-07 30.8 0.9 0.56 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 ORX93777.1 - 6.1e-06 26.4 1.2 0.32 10.9 0.0 3.8 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 ORX93777.1 - 2.1e-05 23.8 20.4 0.033 13.3 0.6 5.5 1 1 2 4 4 4 3 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 ORX93777.1 - 0.00011 22.8 1.0 0.019 15.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX93777.1 - 0.089 13.5 0.1 8.2 7.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat UvdE PF03851.14 ORX93779.1 - 3.5e-95 318.4 0.0 4.3e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 ORX93779.1 - 0.021 14.3 0.0 0.22 10.9 0.0 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Prefoldin PF02996.17 ORX93780.1 - 5.3e-34 116.7 4.0 5.3e-34 116.7 4.0 1.4 2 0 0 2 2 2 1 Prefoldin subunit Ran-binding PF05508.11 ORX93780.1 - 0.008 15.2 6.1 0.13 11.2 0.8 2.0 2 0 0 2 2 2 2 RanGTP-binding protein NUDIX PF00293.28 ORX93781.1 - 1.1e-13 51.4 0.1 1.5e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain fn3 PF00041.21 ORX93782.1 - 7.3e-05 23.0 0.2 0.00016 22.0 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain TMEM40 PF15817.5 ORX93782.1 - 4.9 6.9 5.2 9.8 6.0 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 40 family UPF0182 PF03699.13 ORX93782.1 - 5.9 4.9 6.3 7.9 4.5 6.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) GRP PF07172.11 ORX93783.1 - 7 7.4 16.1 97 3.8 16.1 2.2 1 1 0 1 1 1 0 Glycine rich protein family tRNA-synt_2b PF00587.25 ORX93784.1 - 3.1e-40 138.1 0.0 6.4e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORX93784.1 - 3.7e-10 39.8 0.0 8.3e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.6 ORX93784.1 - 0.0049 16.2 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Peptidase_S8 PF00082.22 ORX93785.1 - 9.7e-33 113.7 12.6 2.3e-32 112.4 12.6 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX93785.1 - 0.0016 19.1 0.1 0.0093 16.6 0.0 1.9 1 1 1 2 2 2 1 Peptidase inhibitor I9 EPSP_synthase PF00275.20 ORX93798.1 - 6.9e-127 423.6 0.0 9.9e-127 423.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORX93798.1 - 1.3e-97 326.0 0.0 4.1e-97 324.5 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase SKI PF01202.22 ORX93798.1 - 9.5e-34 116.8 0.0 5.7e-32 111.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Fe-ADH_2 PF13685.6 ORX93798.1 - 2.4e-08 34.0 0.0 2.9e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ORX93798.1 - 0.0025 16.7 0.8 0.023 13.5 0.6 2.6 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_16 PF13191.6 ORX93798.1 - 0.003 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORX93798.1 - 0.0071 16.8 0.0 0.033 14.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORX93798.1 - 0.031 14.4 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORX93798.1 - 0.032 14.8 0.0 0.086 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORX93798.1 - 0.044 12.9 0.0 0.098 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 ORX93798.1 - 0.12 12.4 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CobW_C PF07683.14 ORX93798.1 - 0.12 12.3 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_14 PF13173.6 ORX93798.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORX93798.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RTC PF01137.21 ORX93798.1 - 0.32 10.2 1.5 4.2 6.5 0.3 3.2 2 2 1 3 3 3 0 RNA 3'-terminal phosphate cyclase ThiF PF00899.21 ORX93799.1 - 3e-18 66.1 0.0 4.9e-18 65.4 0.0 1.3 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORX93799.1 - 0.00076 19.6 0.0 0.77 10.0 0.1 3.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle DpnII PF04556.12 ORX93799.1 - 0.0038 16.6 0.7 0.23 10.8 0.0 2.9 3 0 0 3 3 3 1 DpnII restriction endonuclease C_LFY_FLO PF17538.2 ORX93799.1 - 0.068 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula tRNA-synt_1 PF00133.22 ORX93800.1 - 2.5e-233 775.7 0.2 4e-233 775.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORX93800.1 - 1e-29 103.4 0.1 5.9e-29 101.0 0.1 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORX93800.1 - 9.7e-14 50.9 2.8 6.3e-05 21.9 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ORX93800.1 - 0.0014 18.0 0.0 0.0049 16.2 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Trypsin PF00089.26 ORX93801.1 - 6.3e-46 157.0 0.0 7.2e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX93801.1 - 1.2e-09 39.2 0.1 2.2e-09 38.4 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 ORX93801.1 - 0.0026 17.4 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Sec61_beta PF03911.16 ORX93802.1 - 2.9e-16 59.2 0.5 3.3e-16 59.0 0.5 1.1 1 0 0 1 1 1 1 Sec61beta family Bac_surface_Ag PF01103.23 ORX93803.1 - 4.7e-52 177.5 0.3 6e-52 177.1 0.3 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 ORX93803.1 - 0.032 14.8 0.1 0.08 13.5 0.1 1.7 1 0 0 1 1 1 0 Surface antigen variable number repeat PH PF00169.29 ORX93811.1 - 2.3e-12 47.4 1.0 4.4e-12 46.4 0.6 1.7 1 1 1 2 2 2 1 PH domain PH_8 PF15409.6 ORX93811.1 - 0.17 12.2 0.2 0.31 11.3 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain EB1 PF03271.17 ORX93812.1 - 6.3e-10 39.1 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORX93812.1 - 1.6e-07 31.5 0.1 3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain SlyX PF04102.12 ORX93812.1 - 0.014 16.0 0.8 0.034 14.7 0.8 1.6 1 0 0 1 1 1 0 SlyX COG4 PF08318.12 ORX93812.1 - 0.041 13.0 0.3 0.087 11.9 0.1 1.6 1 1 0 1 1 1 0 COG4 transport protein TSC22 PF01166.18 ORX93812.1 - 0.046 14.0 0.1 0.095 13.0 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family CH_2 PF06294.11 ORX93812.1 - 0.074 13.2 0.3 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 CH-like domain in sperm protein Sec6 PF06046.13 ORX93813.1 - 1.2e-136 456.4 4.8 1.2e-136 456.4 4.8 1.6 2 1 1 3 3 3 1 Exocyst complex component Sec6 RIH_assoc PF08454.11 ORX93813.1 - 2 8.3 9.2 1.7 8.6 3.8 3.3 3 1 0 3 3 3 0 RyR and IP3R Homology associated Tsc35 PF15079.6 ORX93813.1 - 3.1 7.3 7.0 3.8 7.0 5.7 1.8 2 0 0 2 2 2 0 Testis-specific protein 35 Na_H_Exchanger PF00999.21 ORX93814.1 - 1.4e-59 201.9 31.5 1.8e-59 201.5 31.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3112 PF11309.8 ORX93814.1 - 0.047 13.1 0.6 0.12 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) WD40 PF00400.32 ORX93815.1 - 3.8e-50 166.8 19.9 5.6e-10 39.7 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX93815.1 - 5.3e-30 103.6 0.6 4.9e-06 26.7 0.0 7.2 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX93815.1 - 8.9e-10 38.8 0.4 0.0076 16.1 0.1 3.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 ORX93815.1 - 2.3e-09 36.9 0.7 4.1e-09 36.1 0.7 1.5 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 ORX93815.1 - 3.8e-08 33.0 0.0 0.0072 15.7 0.0 3.5 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 ORX93815.1 - 0.0018 17.0 0.1 0.026 13.2 0.0 2.6 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORX93815.1 - 0.0074 15.3 0.4 5.8 5.8 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 ORX93815.1 - 0.019 14.3 0.1 1.2 8.4 0.0 3.3 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 ORX93815.1 - 0.021 13.9 0.0 18 4.2 0.0 3.1 2 2 1 3 3 3 0 Coatomer WD associated region PD40 PF07676.12 ORX93815.1 - 0.11 12.5 0.6 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Atrophin-1 PF03154.15 ORX93815.1 - 2.1 6.5 6.9 2.8 6.1 6.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family NPR3 PF03666.13 ORX93815.1 - 3.8 6.2 7.5 5.4 5.7 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Na_H_Exchanger PF00999.21 ORX93816.1 - 6.7e-58 196.3 37.3 8.5e-58 195.9 37.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Epiglycanin_C PF14654.6 ORX93816.1 - 0.21 11.7 0.9 1.7 8.7 0.2 2.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Pkinase PF00069.25 ORX93820.1 - 6.5e-76 255.2 0.0 8.2e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX93820.1 - 1.8e-50 171.7 0.0 2.5e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORX93820.1 - 1.2e-20 73.6 1.2 1.9e-20 73.0 0.1 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 ORX93820.1 - 6.2e-08 32.3 0.0 8.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX93820.1 - 1.6e-06 27.2 0.1 3.6e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX93820.1 - 0.002 18.1 0.0 0.016 15.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX93820.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORX93820.1 - 0.16 11.3 0.3 0.65 9.3 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S28e PF01200.18 ORX93821.1 - 3e-33 113.6 1.2 3.6e-33 113.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORX93821.1 - 0.069 13.5 0.0 0.099 13.0 0.0 1.3 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORX93821.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region Ribosomal_S4e PF00900.20 ORX93822.1 - 3.5e-36 123.0 0.1 7.1e-36 122.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX93822.1 - 2.2e-26 91.2 0.1 3.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORX93822.1 - 2.8e-21 75.3 6.6 6.5e-21 74.2 6.6 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORX93822.1 - 1.3e-08 34.4 0.1 3.3e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORX93822.1 - 7.1e-05 22.6 4.5 7.1e-05 22.6 4.5 2.6 3 0 0 3 3 3 1 KOW motif Kinesin PF00225.23 ORX93823.1 - 6.3e-114 380.4 2.0 6.3e-114 380.4 2.0 2.9 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 ORX93823.1 - 1e-27 96.9 0.2 1e-27 96.9 0.2 4.1 4 1 0 4 4 4 1 Microtubule binding Microtub_bind PF13931.6 ORX93823.1 - 5.4e-05 23.6 0.1 5.4e-05 23.6 0.1 6.2 3 1 3 7 7 6 1 Kinesin-associated microtubule-binding Tropomyosin PF00261.20 ORX93823.1 - 0.0026 17.1 22.0 0.0026 17.1 22.0 3.5 3 0 0 3 3 3 2 Tropomyosin Syntaxin-6_N PF09177.11 ORX93823.1 - 0.019 15.5 1.4 0.019 15.5 1.4 6.5 5 2 1 6 6 6 0 Syntaxin 6, N-terminal Apolipoprotein PF01442.18 ORX93823.1 - 0.062 13.2 59.5 0.17 11.8 16.5 4.0 2 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain AAA_7 PF12775.7 ORX93823.1 - 0.079 12.5 0.0 0.079 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Baculo_PEP_C PF04513.12 ORX93823.1 - 0.62 10.1 39.7 0.043 13.9 1.7 5.5 1 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.6 ORX93823.1 - 2.3 8.6 0.0 2.3 8.6 0.0 4.3 2 1 2 4 4 4 0 AAA ATPase domain DUF3584 PF12128.8 ORX93823.1 - 2.5 5.5 57.4 1.3 6.4 44.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NYD-SP28_assoc PF14775.6 ORX93823.1 - 9.7 6.4 11.0 1.8 8.8 1.0 4.5 4 0 0 4 4 4 0 Sperm tail C-terminal domain Sec7 PF01369.20 ORX93824.1 - 7.9e-72 240.8 0.7 1.6e-71 239.7 0.7 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORX93824.1 - 6.8e-41 139.8 3.0 3.1e-40 137.7 3.0 2.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORX93824.1 - 2.9e-31 107.1 2.6 2.2e-27 94.7 0.1 4.9 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) EF-hand_1 PF00036.32 ORX93824.1 - 4e-23 79.2 3.8 8.6e-06 24.9 0.0 5.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 ORX93824.1 - 1.2e-20 73.7 7.9 6.1e-09 36.2 0.5 4.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX93824.1 - 4.3e-20 69.9 6.9 2.5e-06 26.9 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain DCB PF16213.5 ORX93824.1 - 2e-18 66.7 9.0 5.1e-18 65.4 1.2 4.5 5 1 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 EF-hand_5 PF13202.6 ORX93824.1 - 2.6e-15 55.1 4.7 0.00012 21.4 0.0 4.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORX93824.1 - 8.6e-14 51.1 6.0 5e-08 32.7 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain pair DUF5640 PF18692.1 ORX93824.1 - 0.011 15.8 0.5 0.039 14.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5640) EF-hand_9 PF14658.6 ORX93824.1 - 0.014 15.7 0.1 0.43 10.9 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain gpW PF02831.15 ORX93824.1 - 0.17 11.8 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 gpW Plasmodium_Vir PF05795.11 ORX93824.1 - 7.6 5.8 6.8 23 4.3 6.8 1.8 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Raffinose_syn PF05691.12 ORX93825.1 - 3.8e-65 220.1 1.0 1.2e-45 155.7 0.6 3.9 1 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 ORX93825.1 - 2e-06 27.0 0.0 3.8e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 ORX93825.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A FAM72 PF14976.6 ORX93826.1 - 4.1e-22 78.9 2.7 5.3e-22 78.5 2.7 1.1 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORX93826.1 - 4.9 7.4 8.6 6.7 7.0 4.4 2.6 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.13 ORX93826.1 - 9.5 6.3 8.4 2.3 8.3 0.1 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Toxin_3 PF00537.18 ORX93827.1 - 0.78 10.0 16.8 0.13 12.5 4.0 2.5 2 1 0 2 2 2 0 Scorpion toxin-like domain Spo7 PF03907.13 ORX93829.1 - 1.3e-06 28.1 0.4 2.1e-06 27.4 0.3 1.3 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 ORX93829.1 - 0.0066 16.8 0.0 0.0095 16.3 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 188 BatA PF07584.11 ORX93829.1 - 0.026 14.9 0.1 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal RRM_1 PF00076.22 ORX93830.1 - 6.9e-32 109.1 0.0 9e-16 57.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX93830.1 - 0.023 14.8 0.0 7 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif p450 PF00067.22 ORX93832.1 - 8.8e-43 146.7 0.1 1.9e-40 139.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Tyrosinase PF00264.20 ORX93833.1 - 3.4e-35 122.4 4.1 3.7e-34 119.0 4.1 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF3322 PF11795.8 ORX93833.1 - 0.063 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) PHD PF00628.29 ORX93835.1 - 1.8e-10 40.5 5.8 1.8e-10 40.5 5.8 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 ORX93835.1 - 0.0018 17.8 5.5 0.0018 17.8 5.5 2.5 2 1 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 ORX93835.1 - 0.033 13.8 1.2 0.033 13.8 1.2 2.1 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Gti1_Pac2 PF09729.9 ORX93836.1 - 8.1e-47 159.6 0.6 5.7e-39 134.1 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Myb_DNA-binding PF00249.31 ORX93837.1 - 4.6e-08 33.1 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX93837.1 - 0.035 14.3 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Exo84_C PF16528.5 ORX93838.1 - 1.4e-55 188.3 1.0 3e-55 187.2 1.0 1.6 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 ORX93838.1 - 7.6e-13 48.4 2.7 7.6e-13 48.4 2.7 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 ORX93838.1 - 0.00023 21.3 1.9 0.00096 19.2 1.9 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PH PF00169.29 ORX93838.1 - 0.023 15.2 0.0 0.066 13.7 0.0 1.8 1 0 0 1 1 1 0 PH domain CheR PF01739.18 ORX93838.1 - 0.09 12.2 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pro_isomerase PF00160.21 ORX93839.1 - 2.6e-46 157.8 0.6 3.2e-44 151.0 0.6 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 ORX93839.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain GCIP PF13324.6 ORX93840.1 - 3e-40 138.5 1.2 4.8e-40 137.8 1.2 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting TPR_19 PF14559.6 ORX93841.1 - 1.6e-16 60.5 2.1 3e-05 24.4 0.0 4.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORX93841.1 - 1.6e-14 52.7 7.5 0.0031 17.5 0.0 6.4 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX93841.1 - 5.9e-14 51.6 0.6 0.034 14.9 0.0 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX93841.1 - 2.4e-12 46.3 2.4 0.0024 18.1 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORX93841.1 - 3e-12 47.0 0.1 0.00093 19.8 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX93841.1 - 1.3e-09 37.5 6.5 0.039 14.2 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX93841.1 - 6e-09 36.1 5.3 0.014 15.7 0.0 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX93841.1 - 1.7e-07 30.7 8.3 0.11 12.3 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX93841.1 - 2e-07 30.6 5.3 0.097 12.4 0.0 5.5 4 2 1 5 5 5 2 TPR repeat ANAPC3 PF12895.7 ORX93841.1 - 4.8e-05 23.5 3.1 0.038 14.2 0.3 3.9 3 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORX93841.1 - 0.00016 21.8 0.0 0.14 12.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX93841.1 - 0.00017 21.4 0.9 4 7.7 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX93841.1 - 0.00017 21.1 0.7 0.017 14.5 0.1 3.2 2 1 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 ORX93841.1 - 0.00017 21.8 0.1 1.3 9.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORX93841.1 - 0.0034 17.4 0.0 0.035 14.2 0.0 2.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 ORX93841.1 - 0.0047 17.5 2.6 3.5 8.5 0.2 4.9 6 1 0 6 6 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 ORX93841.1 - 0.018 14.5 0.5 0.28 10.6 0.2 2.4 2 0 0 2 2 2 0 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 ORX93841.1 - 0.024 15.1 0.4 0.15 12.5 0.1 2.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation HEPN PF05168.14 ORX93841.1 - 0.46 10.6 3.9 3.3 7.9 0.1 3.5 4 1 0 4 4 4 0 HEPN domain Ribosomal_L30_N PF08079.12 ORX93842.1 - 1.5e-22 79.6 16.8 1.5e-22 79.6 16.8 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ORX93842.1 - 6.8e-17 61.1 2.4 6.8e-17 61.1 2.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Med3 PF11593.8 ORX93842.1 - 0.026 13.7 0.7 0.032 13.4 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DSHCT PF08148.12 ORX93842.1 - 0.16 11.6 1.2 0.62 9.7 1.2 1.8 1 1 0 1 1 1 0 DSHCT (NUC185) domain Tipalpha PF16753.5 ORX93842.1 - 0.39 10.5 6.0 6.2 6.6 0.0 2.2 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Ribosomal_L37 PF08561.10 ORX93842.1 - 1.5 9.4 7.3 2.6 8.6 7.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 WD40 PF00400.32 ORX93843.1 - 6e-09 36.4 15.5 0.012 16.4 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Ribosomal_L6e PF01159.19 ORX93844.1 - 2.4e-42 144.0 0.9 2.4e-42 144.0 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORX93844.1 - 1.4e-07 31.7 0.4 1.4e-07 31.7 0.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain eIF3_N PF09440.10 ORX93845.1 - 5.6e-52 175.7 4.6 7.4e-52 175.3 1.9 2.6 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 ORX93845.1 - 1.1e-15 58.1 0.1 2.3e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 ORX93845.1 - 0.025 14.6 1.9 0.47 10.4 0.0 3.1 3 0 0 3 3 3 0 CSN8/PSMD8/EIF3K family RGS PF00615.19 ORX93846.1 - 4.4e-14 52.8 0.5 7.8e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX93847.1 - 4.4e-14 52.8 0.5 7.8e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain tRNA_Me_trans PF03054.16 ORX93848.1 - 1.3e-127 425.5 0.0 1.4e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 ORX93848.1 - 0.00022 20.9 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 ORX93848.1 - 0.00034 19.8 0.0 0.0041 16.3 0.0 2.1 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 ORX93848.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 ORX93848.1 - 0.063 12.8 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 ORX93848.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 PP-loop family Efg1 PF10153.9 ORX93849.1 - 4.8e-35 120.4 16.5 4.8e-35 120.4 16.5 1.9 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Chs7 PF12271.8 ORX93852.1 - 4.3e-96 321.6 7.5 5e-96 321.5 7.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Methyltransf_23 PF13489.6 ORX93853.1 - 1.2e-06 28.5 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX93853.1 - 2.6e-05 24.9 0.1 0.00025 21.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX93853.1 - 0.00083 19.2 0.1 0.0018 18.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX93853.1 - 0.0014 19.3 0.0 0.0042 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ORX93853.1 - 0.0043 16.4 0.0 0.97 8.7 0.0 2.2 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Pox_VLTF3 PF04947.14 ORX93853.1 - 0.016 14.9 0.3 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like MTS PF05175.14 ORX93853.1 - 0.027 14.0 0.0 0.089 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 ORX93853.1 - 0.029 15.0 0.0 0.28 11.8 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain DREV PF05219.12 ORX93853.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Aldo_ket_red PF00248.21 ORX93868.1 - 8.8e-72 241.8 0.0 1e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_tail_X PF05489.12 ORX93868.1 - 0.079 12.6 0.1 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Phage Tail Protein X Cyclin PF08613.11 ORX93869.1 - 2.2e-38 132.1 0.5 4.2e-38 131.3 0.5 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX93869.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain COX5A PF02284.16 ORX93869.1 - 0.045 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va LRR_4 PF12799.7 ORX93870.1 - 1e-06 28.9 12.0 0.42 11.1 0.0 7.4 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) HABP4_PAI-RBP1 PF04774.15 ORX93870.1 - 0.26 12.1 4.7 0.52 11.2 4.7 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family LRR_4 PF12799.7 ORX93871.1 - 9.1e-05 22.8 10.2 1.7 9.2 0.0 7.4 6 1 3 9 9 9 4 Leucine Rich repeats (2 copies) DAO PF01266.24 ORX93872.1 - 3.6e-61 207.7 0.0 2.6e-60 204.9 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Fer2_BFD PF04324.15 ORX93872.1 - 3.7e-16 59.2 1.0 9.7e-16 57.9 1.0 1.8 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain NAD_binding_8 PF13450.6 ORX93872.1 - 3e-07 30.6 0.1 6.4e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORX93872.1 - 5.1e-05 23.7 0.6 0.011 16.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX93872.1 - 0.00027 20.1 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORX93872.1 - 0.00029 20.2 0.2 0.00081 18.7 0.2 1.7 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 ORX93872.1 - 0.00031 21.0 0.1 0.00079 19.7 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 ORX93872.1 - 0.00057 19.2 0.2 0.0098 15.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX93872.1 - 0.0036 16.1 0.1 0.0065 15.2 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORX93872.1 - 0.004 16.3 0.2 0.0076 15.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 ORX93872.1 - 0.0093 15.2 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 ORX93872.1 - 0.019 14.6 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 ORX93872.1 - 0.022 15.0 0.1 0.06 13.6 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 ORX93872.1 - 0.037 13.3 0.2 0.12 11.6 0.0 2.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ORX93872.1 - 0.046 13.1 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORX93872.1 - 0.06 13.4 0.1 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORX93872.1 - 0.079 12.8 0.1 0.079 12.8 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lyase_1 PF00206.20 ORX93872.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Lyase SO_alpha_A3 PF17806.1 ORX93872.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain Ribo_biogen_C PF04034.13 ORX93873.1 - 3e-05 23.7 0.3 0.28 10.9 0.0 2.6 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal Thi4 PF01946.17 ORX93873.1 - 0.094 11.9 1.7 0.16 11.2 0.2 1.9 1 1 1 2 2 2 0 Thi4 family Ribo_biogen_C PF04034.13 ORX93874.1 - 1.1e-05 25.1 0.3 0.3 10.8 0.0 2.9 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal Ribo_biogen_C PF04034.13 ORX93875.1 - 1.8e-05 24.5 0.4 0.28 10.9 0.0 2.9 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal Ribo_biogen_C PF04034.13 ORX93876.1 - 1.9e-05 24.4 0.2 0.32 10.7 0.0 2.9 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal Thi4 PF01946.17 ORX93876.1 - 0.053 12.8 1.1 0.11 11.7 0.1 1.8 1 1 1 2 2 2 0 Thi4 family Ribo_biogen_C PF04034.13 ORX93877.1 - 1.6e-05 24.7 0.4 0.27 11.0 0.0 2.9 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal GRP PF07172.11 ORX93877.1 - 8.6 7.1 12.6 16 6.2 12.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ribo_biogen_C PF04034.13 ORX93878.1 - 1.6e-05 24.6 0.3 0.3 10.8 0.0 2.9 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal Thi4 PF01946.17 ORX93878.1 - 0.053 12.8 0.9 0.13 11.5 0.1 1.9 1 1 1 2 2 2 0 Thi4 family Zn_ribbon_17 PF17120.5 ORX93879.1 - 0.00011 21.7 1.1 0.00011 21.7 1.1 2.5 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ORX93879.1 - 0.0028 17.7 0.1 0.0028 17.7 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ORX93879.1 - 0.026 14.8 1.2 0.026 14.8 1.2 3.0 3 0 0 3 3 3 0 Ring finger domain RINGv PF12906.7 ORX93879.1 - 0.046 13.9 0.4 0.046 13.9 0.4 2.0 2 0 0 2 2 2 0 RING-variant domain zf-rbx1 PF12678.7 ORX93879.1 - 0.22 11.8 7.3 0.7 10.2 7.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD_4 PF16866.5 ORX93879.1 - 2.6 8.2 8.8 3.7 7.7 3.8 3.2 2 1 0 2 2 2 0 PHD-finger AP_endonuc_2 PF01261.24 ORX93880.1 - 7.2e-33 113.8 0.0 1.2e-32 113.0 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel LRR_4 PF12799.7 ORX93881.1 - 2.9e-06 27.5 14.7 0.73 10.3 0.1 7.6 6 3 2 9 9 9 4 Leucine Rich repeats (2 copies) SDA1 PF05285.12 ORX93881.1 - 0.52 9.7 8.6 0.13 11.7 4.5 1.8 2 0 0 2 2 2 0 SDA1 LRR_6 PF13516.6 ORX93881.1 - 0.54 10.4 7.1 1 9.6 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat CDC45 PF02724.14 ORX93881.1 - 4.6 5.4 7.7 7.4 4.7 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORX93881.1 - 7 4.7 10.4 14 3.7 10.4 1.4 1 0 0 1 1 1 0 Nop14-like family DSPc PF00782.20 ORX93882.1 - 5.1e-31 107.2 0.1 7.7e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX93882.1 - 0.00088 18.9 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 ORX93882.1 - 0.057 13.7 0.0 0.098 13.0 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Zn_ribbon_SprT PF17283.2 ORX93882.1 - 0.15 12.0 6.0 1.3 9.0 0.2 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Proteasome PF00227.26 ORX93883.1 - 1.7e-37 128.7 0.0 2e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PALP PF00291.25 ORX93884.1 - 5.4e-63 213.1 0.0 6.3e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_8 PF01501.20 ORX93885.1 - 7e-24 84.8 0.0 6.3e-23 81.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORX93885.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORX93885.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Pro_isomerase PF00160.21 ORX93886.1 - 6.2e-48 163.0 0.5 7.6e-48 162.8 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 ORX93887.1 - 1.8e-47 161.6 0.4 2.2e-47 161.2 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.7 ORX93888.1 - 1.6e-05 25.1 0.6 1.6e-05 25.1 0.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORX93888.1 - 2.8e-05 24.4 3.3 2.8e-05 24.4 3.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX93888.1 - 3.2e-05 23.7 2.1 0.00013 21.8 2.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX93888.1 - 0.00014 21.7 1.8 0.00014 21.7 1.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX93888.1 - 0.002 18.0 2.3 0.002 18.0 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 ORX93888.1 - 0.0022 18.0 6.5 0.013 15.5 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) DZR PF12773.7 ORX93888.1 - 0.0084 16.1 5.7 1.5 8.9 0.6 2.8 2 0 0 2 2 2 2 Double zinc ribbon zf-RING_UBOX PF13445.6 ORX93888.1 - 0.029 14.4 0.6 0.14 12.2 0.6 2.2 1 0 0 1 1 1 0 RING-type zinc-finger CEP63 PF17045.5 ORX93888.1 - 0.034 14.0 1.0 0.057 13.3 0.1 1.6 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa zf-RING_5 PF14634.6 ORX93888.1 - 0.038 13.9 1.9 0.038 13.9 1.9 2.8 3 0 0 3 3 3 0 zinc-RING finger domain HIP1_clath_bdg PF16515.5 ORX93888.1 - 0.13 12.9 2.0 2.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-RING_4 PF14570.6 ORX93888.1 - 0.22 11.4 8.3 0.78 9.6 2.6 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 ORX93888.1 - 0.31 10.9 6.8 0.044 13.6 1.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORX93888.1 - 1.5 8.9 6.0 1.2 9.3 0.5 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 ORX93888.1 - 1.6 8.8 6.3 1.7 8.7 0.6 2.7 2 0 0 2 2 2 0 zinc-ribbons UPF0547 PF10571.9 ORX93888.1 - 2.4 8.3 6.6 5.2 7.3 2.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C4pol PF14260.6 ORX93888.1 - 4.7 7.7 8.1 17 5.9 0.3 3.5 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta ECH_1 PF00378.20 ORX93889.1 - 2.2e-35 122.2 0.0 2.7e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX93889.1 - 3.8e-12 46.4 0.0 6.6e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TFIIE_alpha PF02002.17 ORX93889.1 - 0.02 14.8 0.1 0.052 13.4 0.1 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit SAMP PF05924.11 ORX93889.1 - 0.27 10.6 1.8 0.53 9.6 1.8 1.5 1 0 0 1 1 1 0 SAMP Motif WD40 PF00400.32 ORX93890.1 - 3.2e-31 106.9 17.0 5.3e-08 33.4 0.4 6.4 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX93890.1 - 3.6e-05 24.0 0.3 0.23 11.8 0.0 4.3 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX93890.1 - 0.034 12.8 0.1 1.9 7.1 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 phiKZ_IP PF12699.7 ORX93890.1 - 0.068 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins SH3_9 PF14604.6 ORX93891.1 - 3.3e-05 23.6 0.1 5.6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX93891.1 - 7.8e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX93891.1 - 0.024 14.3 1.1 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain Gly-zipper_Omp PF13488.6 ORX93891.1 - 0.096 12.7 21.2 0.038 14.0 1.8 2.6 2 1 0 2 2 2 0 Glycine zipper Beta-APP PF03494.13 ORX93891.1 - 0.23 11.3 3.9 0.45 10.4 3.9 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) S1FA PF04689.13 ORX93891.1 - 0.24 11.6 0.1 0.43 10.8 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Gly-zipper_OmpA PF13436.6 ORX93891.1 - 8.8 6.2 20.9 0.19 11.5 5.3 2.4 2 0 0 2 2 2 0 Glycine-zipper domain Sigma_1s PF02454.16 ORX93892.1 - 0.017 15.1 0.8 0.19 11.7 0.3 2.2 1 1 1 2 2 2 0 Sigma 1s protein Asn_synthase PF00733.21 ORX93894.1 - 5.1e-20 72.4 0.1 1.2e-13 51.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase DZR PF12773.7 ORX93894.1 - 0.0011 19.0 1.7 0.0033 17.4 1.7 1.8 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 ORX93894.1 - 0.34 10.4 3.6 0.84 9.1 3.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 ORX93894.1 - 0.69 9.7 4.1 1.7 8.5 4.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain MCM PF00493.23 ORX93895.1 - 4.1e-103 343.3 0.5 7e-103 342.5 0.5 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORX93895.1 - 3.2e-39 133.6 0.6 7.3e-39 132.5 0.6 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 ORX93895.1 - 3.1e-25 88.5 1.4 3.1e-25 88.5 1.4 2.2 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 ORX93895.1 - 5.9e-25 87.5 1.6 1.1e-24 86.7 0.8 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 ORX93895.1 - 3.6e-23 82.1 3.1 1e-22 80.6 3.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORX93895.1 - 5.1e-08 32.5 0.0 1.5e-06 27.8 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORX93895.1 - 0.0019 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 ORX93895.1 - 0.002 18.2 0.0 0.0049 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORX93895.1 - 0.0032 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nucleoporin2 PF04096.14 ORX93896.1 - 1.4e-28 99.9 0.0 2.5e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase ERCC4 PF02732.15 ORX93909.1 - 1.9e-20 73.7 0.0 5.5e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain DUF842 PF05811.13 ORX93909.1 - 0.032 13.9 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Sulfate_transp PF00916.20 ORX93910.1 - 7.2e-56 189.6 17.2 1.2e-55 188.9 17.2 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ORX93910.1 - 6.9e-17 61.3 0.0 1.4e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORX93910.1 - 6.1e-09 35.5 0.1 1.4e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORX93910.1 - 0.11 13.0 14.2 0.53 10.7 0.6 3.1 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily FAM176 PF14851.6 ORX93910.1 - 4.4 7.0 5.4 7.2 6.3 0.1 2.4 2 0 0 2 2 2 0 FAM176 family EST1_DNA_bind PF10373.9 ORX93911.1 - 2.7e-35 122.3 4.7 8.5e-35 120.6 4.7 1.9 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 ORX93911.1 - 3.3e-21 75.9 2.5 4.4e-21 75.5 0.0 2.4 2 0 0 2 2 2 1 PIN domain EST1 PF10374.9 ORX93911.1 - 2.1e-09 38.1 5.5 2.1e-09 38.1 5.5 4.1 5 0 0 5 5 5 1 Telomerase activating protein Est1 TPR_17 PF13431.6 ORX93911.1 - 0.09 13.2 0.0 0.35 11.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PIN_9 PF18477.1 ORX93911.1 - 0.15 12.3 0.7 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 PIN like domain CHASE6_C PF17150.4 ORX93911.1 - 0.51 11.0 4.0 0.58 10.9 1.1 2.7 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain SIS PF01380.22 ORX93912.1 - 1e-23 83.6 0.0 2.5e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 ORX93912.1 - 4e-15 56.0 0.7 4.1e-06 27.1 0.1 3.1 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 ORX93912.1 - 6.2e-08 32.8 0.0 0.00084 19.4 0.0 2.4 1 1 1 2 2 2 2 SIS domain BAAT_C PF08840.11 ORX93912.1 - 0.073 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ras PF00071.22 ORX93914.1 - 1.2e-54 184.3 0.2 1.4e-54 184.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX93914.1 - 5.5e-30 104.1 0.1 8e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX93914.1 - 9.7e-17 61.0 0.1 1.2e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX93914.1 - 1.4e-06 28.3 0.0 2.8e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX93914.1 - 1.1e-05 25.0 0.1 2e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX93914.1 - 0.00041 20.3 0.6 0.53 10.2 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 ORX93914.1 - 0.0036 16.9 0.2 0.41 10.2 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 ORX93914.1 - 0.0062 15.9 0.1 0.0075 15.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 ORX93914.1 - 0.024 14.7 0.3 0.053 13.6 0.3 1.9 1 1 0 1 1 1 0 Dynamin family gp45-slide_C PF09116.10 ORX93914.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Aa_trans PF01490.18 ORX93915.1 - 9.1e-81 271.6 36.6 1.2e-80 271.3 36.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-C2H2 PF00096.26 ORX93916.1 - 1.7e-12 47.0 18.4 3.4e-05 24.1 3.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX93916.1 - 3.7e-11 42.9 11.2 2.7e-06 27.5 1.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX93916.1 - 4.8e-11 42.5 15.9 0.0003 21.4 3.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX93916.1 - 7.3e-06 26.1 5.4 0.21 11.9 0.1 3.4 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX93916.1 - 0.0004 20.7 5.9 1.7 9.1 0.0 3.6 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-trcl PF13451.6 ORX93916.1 - 0.0019 18.0 0.9 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 Probable zinc-ribbon domain Ephrin_rec_like PF07699.13 ORX93916.1 - 0.022 14.5 1.7 0.12 12.1 0.3 2.2 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-C2H2_8 PF15909.5 ORX93916.1 - 0.038 14.3 6.6 0.049 13.9 5.6 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 ORX93916.1 - 0.045 13.9 3.5 2.5 8.3 0.1 2.4 1 1 1 2 2 2 0 Zic proteins zinc finger domain DUF3449 PF11931.8 ORX93916.1 - 0.13 12.1 0.4 1.1 9.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) C1_4 PF07975.12 ORX93916.1 - 0.65 10.3 5.8 6.3 7.1 6.4 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-AN1 PF01428.16 ORX93916.1 - 5 7.4 15.4 87 3.4 0.7 3.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-H2C2_2 PF13465.6 ORX93917.1 - 9.5e-09 35.3 13.5 1.6e-07 31.4 1.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX93917.1 - 8.1e-05 23.1 12.2 0.026 15.3 6.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX93917.1 - 0.00013 22.2 21.4 0.0013 19.1 9.0 3.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 ORX93917.1 - 0.053 13.4 0.9 0.053 13.4 0.9 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 ORX93917.1 - 0.065 13.9 2.6 0.13 12.9 0.9 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-ACC PF17848.1 ORX93917.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 ORX93917.1 - 0.17 11.5 5.1 3.4 7.3 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 ORX93917.1 - 0.53 10.5 14.2 2.4 8.4 8.6 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger zf-FCS PF06467.14 ORX93917.1 - 1.8 8.6 10.2 0.77 9.8 1.2 2.8 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-UBP PF02148.19 ORX93917.1 - 2.2 8.7 10.6 16 5.9 10.6 2.1 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Aa_trans PF01490.18 ORX93918.1 - 2.8e-69 233.8 45.5 3.2e-69 233.6 45.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORX93918.1 - 2.9e-08 33.0 52.4 1e-07 31.1 52.4 1.8 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 ORX93918.1 - 0.00036 19.5 28.3 0.00036 19.5 28.3 2.5 1 1 1 2 2 2 1 Spore germination protein Tropomyosin_1 PF12718.7 ORX93919.1 - 1.9e-41 141.6 50.7 4e-27 95.1 25.1 2.0 2 0 0 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 ORX93919.1 - 1.6e-15 57.2 53.0 2.3e-07 30.4 21.3 4.1 2 2 2 4 4 4 4 Tropomyosin DHR10 PF18595.1 ORX93919.1 - 7.4e-07 29.2 57.3 0.0032 17.5 15.8 4.3 2 2 2 4 4 4 3 Designed helical repeat protein 10 domain Sugarporin_N PF11471.8 ORX93919.1 - 0.012 15.6 1.1 0.012 15.6 1.1 6.1 6 1 1 7 7 7 0 Maltoporin periplasmic N-terminal extension DUF5082 PF16888.5 ORX93919.1 - 0.073 13.3 35.6 0.05 13.9 6.9 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 ORX93919.1 - 0.088 13.0 33.5 0.45 10.7 10.8 3.8 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 ORX93919.1 - 0.1 10.1 40.4 0.024 12.2 20.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HOOK PF05622.12 ORX93919.1 - 0.16 10.1 44.2 0.066 11.4 14.3 2.2 2 0 0 2 2 2 0 HOOK protein GAS PF13851.6 ORX93919.1 - 0.18 11.1 48.3 0.69 9.2 7.8 3.6 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 ORX93919.1 - 0.3 10.8 46.0 1.5 8.6 6.8 3.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) SesA PF17107.5 ORX93919.1 - 0.34 11.1 19.3 0.4 10.9 8.4 2.7 2 2 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Uso1_p115_C PF04871.13 ORX93919.1 - 0.65 10.4 50.0 3 8.2 9.7 4.0 1 1 4 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.14 ORX93919.1 - 0.67 9.7 22.1 0.14 11.9 4.1 3.5 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.9 ORX93919.1 - 0.89 9.6 59.0 0.13 12.3 21.2 3.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 ORX93919.1 - 1 9.3 30.9 0.81 9.7 3.1 4.4 2 2 2 4 4 4 0 Laminin Domain II MscS_porin PF12795.7 ORX93919.1 - 1.2 8.6 43.1 1.7 8.1 16.0 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 ORX93919.1 - 1.4 9.0 50.9 1 9.4 2.3 5.3 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 ORX93919.1 - 1.9 7.8 46.2 0.6 9.5 14.8 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CLZ PF16526.5 ORX93919.1 - 2.4 8.6 41.1 0.17 12.3 2.1 5.9 1 1 4 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 ORX93919.1 - 2.4 8.6 45.5 10 6.5 12.3 3.1 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 ORX93919.1 - 2.6 8.1 29.9 1.4 9.0 5.6 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DegS PF05384.11 ORX93919.1 - 3.2 7.2 39.7 1.5 8.3 0.9 4.1 2 2 0 3 3 3 0 Sensor protein DegS DUF1993 PF09351.10 ORX93919.1 - 4 7.6 12.9 0.31 11.2 5.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) UPF0242 PF06785.11 ORX93919.1 - 4.4 7.4 50.4 0.044 13.9 10.4 3.2 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 ORX93919.1 - 5 7.3 39.0 6.4 6.9 10.2 4.1 2 2 0 2 2 2 0 Up-regulated During Septation ADIP PF11559.8 ORX93919.1 - 5.3 7.1 47.0 0.037 14.1 10.2 4.0 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.10 ORX93919.1 - 5.5 7.4 33.3 0.77 10.1 1.7 4.5 2 2 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) MAD PF05557.13 ORX93919.1 - 5.9 5.1 50.5 3.2 6.0 26.9 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein ATG16 PF08614.11 ORX93919.1 - 6.4 6.9 54.7 4.3 7.5 7.2 4.1 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) ERM PF00769.19 ORX93919.1 - 7 6.4 60.3 6 6.6 9.9 3.7 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Histone_H2A_C PF16211.5 ORX93920.1 - 2.3e-20 72.0 2.5 4.2e-20 71.2 2.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORX93920.1 - 1.8e-16 60.7 0.0 2.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORX93920.1 - 2.8e-05 24.3 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase PF00122.20 ORX93922.1 - 6.7e-28 97.4 0.0 7.5e-27 94.0 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORX93922.1 - 5.5e-05 23.5 1.4 0.03 14.6 0.4 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX93922.1 - 0.0019 17.8 1.6 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus MgtE PF01769.16 ORX93922.1 - 0.05 14.0 0.4 0.05 14.0 0.4 4.4 4 1 0 4 4 4 0 Divalent cation transporter S6PP PF05116.13 ORX93922.1 - 0.18 11.3 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MFS_1 PF07690.16 ORX93923.1 - 8.1e-58 196.0 30.8 8.1e-39 133.5 2.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX93923.1 - 5.2e-17 61.8 23.5 2.9e-13 49.4 23.5 3.2 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 ORX93923.1 - 2.4e-12 46.9 12.4 1.1e-11 44.7 0.7 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ORX93923.1 - 2e-11 43.0 12.5 9.5e-07 27.6 2.5 3.6 2 2 1 3 3 3 2 Transmembrane secretion effector MFS_2 PF13347.6 ORX93923.1 - 1.8e-07 30.1 28.4 5.2e-05 22.0 5.5 3.0 2 2 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 ORX93923.1 - 0.013 13.8 19.9 0.46 8.7 4.9 3.6 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_I_TF PF04090.12 ORX93923.1 - 0.22 11.0 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor DUF4131 PF13567.6 ORX93923.1 - 1.4 8.5 7.7 14 5.3 2.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) WD40 PF00400.32 ORX93939.1 - 2.7e-11 43.8 5.2 0.23 12.4 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX93939.1 - 0.0017 18.6 0.0 12 6.3 0.0 4.4 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1652 PF07865.11 ORX93939.1 - 0.058 13.2 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DIL PF01843.19 ORX93940.1 - 2.7e-28 98.3 1.7 9.8e-28 96.5 1.7 2.0 1 0 0 1 1 1 1 DIL domain Ank_5 PF13857.6 ORX93940.1 - 0.00012 22.2 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) YhdB PF14148.6 ORX93940.1 - 0.076 13.1 2.5 0.12 12.5 0.3 2.6 2 1 0 2 2 2 0 YhdB-like protein SapB_1 PF05184.15 ORX93940.1 - 0.13 12.3 0.2 0.34 11.0 0.2 1.8 1 0 0 1 1 1 0 Saposin-like type B, region 1 PqqD PF05402.12 ORX93940.1 - 0.25 11.7 2.4 13 6.2 0.2 2.8 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) AAA_18 PF13238.6 ORX93940.1 - 0.31 11.6 1.9 0.81 10.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain Sds3 PF08598.11 ORX93941.1 - 6.2e-11 42.7 6.8 6.6e-11 42.6 4.7 1.7 1 1 1 2 2 2 1 Sds3-like FHIPEP PF00771.20 ORX93941.1 - 0.13 10.7 0.3 0.16 10.4 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family Pyridoxal_deC PF00282.19 ORX93942.1 - 1.9e-23 82.8 0.0 2.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORX93942.1 - 1.9e-09 37.0 0.0 4.8e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORX93942.1 - 2.4e-09 37.0 0.1 3.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORX93942.1 - 0.037 12.6 0.0 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme KilA-N PF04383.13 ORX93943.1 - 6.8e-05 22.7 0.1 0.00064 19.6 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Glyoxalase PF00903.25 ORX93944.1 - 2.1e-22 79.6 0.0 2.4e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORX93944.1 - 1.2e-08 35.2 0.0 4.5e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORX93944.1 - 0.014 15.3 0.2 0.24 11.3 0.1 2.2 2 1 0 2 2 2 0 Glyoxalase-like domain CppA_N PF14506.6 ORX93944.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal Glyoxalase_6 PF18029.1 ORX93944.1 - 0.034 15.0 0.0 0.064 14.0 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Nab6_mRNP_bdg PF10567.9 ORX93944.1 - 0.079 12.4 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA-recognition motif Glyoxalase_3 PF13468.6 ORX93944.1 - 0.09 12.9 0.0 0.52 10.4 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Endosulfine PF04667.17 ORX93945.1 - 8.6e-28 96.3 0.2 1.3e-27 95.8 0.2 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region YABBY PF04690.13 ORX93946.1 - 2.3e-09 38.0 0.3 2.5e-09 37.9 0.3 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 ORX93946.1 - 5.5e-07 30.2 0.2 6.1e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORX93946.1 - 7.9e-06 26.2 0.2 1.1e-05 25.8 0.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX93946.1 - 0.0055 17.3 0.1 0.007 16.9 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain DOG1 PF14144.6 ORX93946.1 - 0.045 14.0 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Seed dormancy control Gly_transf_sug PF04488.15 ORX93948.1 - 1.2e-07 32.2 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORX93948.1 - 8.9e-05 22.0 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORX93948.1 - 0.063 12.6 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Lactamase_B PF00753.27 ORX93949.1 - 0.002 18.2 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily GXWXG PF14231.6 ORX93949.1 - 0.018 15.1 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 GXWXG protein zf-RING_2 PF13639.6 ORX93949.1 - 0.028 14.7 3.0 4.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Ring finger domain Lactamase_B_5 PF14597.6 ORX93949.1 - 0.056 12.9 0.0 0.096 12.2 0.0 1.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 ORX93950.1 - 1.1e-52 179.2 46.2 1.1e-52 179.2 46.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX93950.1 - 4.4e-15 55.5 12.8 4.4e-15 55.5 12.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX93950.1 - 1.6e-14 53.3 26.1 2.9e-14 52.4 26.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2527 PF10736.9 ORX93950.1 - 0.15 11.9 0.3 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) BK_channel_a PF03493.18 ORX93957.1 - 5.1e-19 68.3 0.0 9.9e-18 64.2 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORX93957.1 - 5.3e-13 48.7 6.2 1.5e-12 47.3 6.2 1.8 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 ORX93957.1 - 4.8e-08 33.3 0.3 0.037 14.3 0.1 3.3 2 1 1 3 3 3 3 TrkA-N domain Ion_trans PF00520.31 ORX93957.1 - 0.0013 18.0 8.8 0.0026 17.0 8.8 1.5 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 ORX93957.1 - 0.022 14.6 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel Ribosomal_S26e PF01283.19 ORX93957.1 - 0.066 13.7 0.2 0.17 12.4 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S26e MFS_1 PF07690.16 ORX93958.1 - 8.3e-35 120.3 46.3 1.9e-28 99.4 25.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX93958.1 - 1.7e-07 30.5 11.6 1e-06 27.9 1.5 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3311 PF11755.8 ORX93958.1 - 0.043 13.7 3.1 0.056 13.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) LacY_symp PF01306.19 ORX93958.1 - 0.2 10.4 14.7 0.15 10.8 1.6 2.6 2 1 0 2 2 2 0 LacY proton/sugar symporter MFS_3 PF05977.13 ORX93958.1 - 0.39 9.0 10.4 1.5 7.1 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Amidohydro_1 PF01979.20 ORX93959.1 - 1e-19 71.1 0.2 2.7e-19 69.7 0.2 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX93959.1 - 4.5e-09 36.3 0.2 1.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.21 ORX93959.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family CBM_21 PF03370.13 ORX93960.1 - 4.9e-29 100.8 0.6 8.2e-29 100.1 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORX93960.1 - 1.2e-10 41.8 0.7 3.7e-10 40.2 0.7 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DNA_pol_A_exo1 PF01612.20 ORX93961.1 - 1.9e-21 76.6 0.0 9.7e-20 71.0 0.0 2.4 2 1 1 3 3 3 2 3'-5' exonuclease Helicase_C PF00271.31 ORX93962.1 - 1.8e-15 57.3 0.4 1.1e-14 54.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX93962.1 - 1.4e-05 25.1 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RB_A PF01858.17 ORX93962.1 - 0.043 13.6 0.3 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain bZIP_2 PF07716.15 ORX93963.1 - 3.6e-06 27.0 15.5 7.8e-06 25.9 15.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX93963.1 - 5e-06 26.5 12.9 1e-05 25.6 12.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX93963.1 - 5.2e-05 23.7 5.9 0.00012 22.5 5.9 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor PRP1_N PF06424.12 ORX93963.1 - 6.2 7.2 9.9 1.1 9.7 4.6 2.4 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal SnoaL_2 PF12680.7 ORX93964.1 - 0.13 12.9 0.0 3.6 8.3 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like domain LRR_8 PF13855.6 ORX93965.1 - 4.3e-25 87.2 25.5 7.9e-08 31.9 3.9 5.0 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORX93965.1 - 1.7e-16 60.1 23.2 3e-07 30.7 0.5 5.3 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX93965.1 - 3.3e-07 29.9 18.0 0.39 11.4 0.1 8.6 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 ORX93965.1 - 0.00082 19.2 24.6 0.12 12.5 0.2 7.4 7 0 0 7 7 7 2 Leucine Rich repeat LRRNT_2 PF08263.12 ORX93965.1 - 0.004 17.4 7.9 0.008 16.5 7.9 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 ORX93965.1 - 0.47 9.9 2.8 2 7.9 0.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeat HARE-HTH PF05066.13 ORX93966.1 - 0.058 13.8 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain KilA-N PF04383.13 ORX93966.1 - 0.15 11.9 0.0 20 5.1 0.0 3.4 3 1 0 3 3 3 0 KilA-N domain GPP34 PF05719.11 ORX93967.1 - 0.0029 17.7 0.0 0.0031 17.6 0.0 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M24_C PF16188.5 ORX93967.1 - 0.11 12.6 0.3 11 6.2 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Zip PF02535.22 ORX93986.1 - 3.4e-35 121.9 17.0 2e-23 83.2 12.4 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter DUF2919 PF11143.8 ORX93986.1 - 0.056 13.8 0.5 0.056 13.8 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) MPC PF03650.13 ORX93987.1 - 2.2e-37 127.6 0.0 2.6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Cep57_MT_bd PF06657.13 ORX93988.1 - 1.8e-13 50.7 5.5 1.8e-13 50.7 5.5 5.1 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Trehalase PF01204.18 ORX93988.1 - 0.023 13.5 0.0 0.023 13.5 0.0 2.4 2 1 0 2 2 2 0 Trehalase MAP65_ASE1 PF03999.12 ORX93989.1 - 3.4e-30 105.3 22.7 3.4e-30 105.3 22.7 1.3 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Ku_C PF03730.14 ORX93989.1 - 0.032 14.9 1.2 0.099 13.3 0.1 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm GAT PF03127.14 ORX93989.1 - 0.3 11.4 2.6 0.59 10.5 0.4 2.6 2 1 0 2 2 2 0 GAT domain CBM9_1 PF06452.11 ORX93990.1 - 2.9e-09 37.1 0.2 5e-09 36.3 0.2 1.5 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like Epimerase PF01370.21 ORX93991.1 - 4.9e-25 88.4 0.0 8.1e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX93991.1 - 5.2e-17 62.3 0.6 1.9e-15 57.1 0.0 2.6 2 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORX93991.1 - 2.8e-13 49.6 0.0 4.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX93991.1 - 5.8e-09 35.3 0.0 8.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORX93991.1 - 2.5e-07 30.1 0.1 1e-06 28.1 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORX93991.1 - 7e-07 28.7 0.1 4.4e-06 26.1 0.1 2.2 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 ORX93991.1 - 0.021 14.7 0.6 0.88 9.4 0.6 2.3 1 1 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 ORX93992.1 - 1.5e-36 125.6 1.2 2.4e-36 124.9 1.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93992.1 - 1.7e-20 73.6 0.0 3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX93992.1 - 0.00093 18.9 0.5 0.014 15.1 0.5 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORX93992.1 - 0.011 16.3 1.1 0.09 13.4 0.4 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX93992.1 - 0.034 13.5 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORX93992.1 - 0.052 13.4 1.4 0.08 12.8 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HBS1_N PF08938.10 ORX93992.1 - 0.084 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus UDPG_MGDP_dh_N PF03721.14 ORX93992.1 - 0.11 12.1 2.5 0.17 11.4 0.9 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 ORX93992.1 - 3.3 7.2 5.3 34 3.8 3.6 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Ldh_1_N PF00056.23 ORX93993.1 - 1.4e-27 96.6 1.2 5.8e-27 94.5 1.2 1.9 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93993.1 - 1.4e-20 73.9 0.0 2.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX93993.1 - 0.013 15.1 0.3 0.043 13.5 0.3 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORX93993.1 - 0.019 14.9 0.4 0.047 13.6 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORX93993.1 - 0.049 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORX93993.1 - 0.051 13.1 0.7 0.14 11.7 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HBS1_N PF08938.10 ORX93993.1 - 0.076 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus F420_oxidored PF03807.17 ORX93993.1 - 0.11 13.1 0.9 1.6 9.4 0.3 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 ORX93994.1 - 1.5e-36 125.5 1.2 2.4e-36 124.9 1.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93994.1 - 1.8e-20 73.5 0.0 3.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX93994.1 - 0.00099 18.8 0.6 0.015 14.9 0.6 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORX93994.1 - 0.011 16.3 1.1 0.09 13.4 0.4 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX93994.1 - 0.038 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORX93994.1 - 0.051 13.5 1.4 0.08 12.8 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HBS1_N PF08938.10 ORX93994.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus UDPG_MGDP_dh_N PF03721.14 ORX93994.1 - 0.11 12.1 2.5 0.17 11.4 0.9 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 ORX93994.1 - 2.3 7.7 4.8 25 4.3 3.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Ldh_1_N PF00056.23 ORX93995.1 - 1.5e-36 125.6 1.2 2.4e-36 124.9 1.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93995.1 - 1.7e-20 73.7 0.0 3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX93995.1 - 0.00093 18.9 0.5 0.014 15.1 0.5 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORX93995.1 - 0.011 16.3 1.1 0.09 13.4 0.4 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX93995.1 - 0.038 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORX93995.1 - 0.051 13.5 1.4 0.08 12.8 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HBS1_N PF08938.10 ORX93995.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus UDPG_MGDP_dh_N PF03721.14 ORX93995.1 - 0.11 12.1 2.5 0.17 11.4 0.9 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 ORX93995.1 - 3.3 7.2 5.3 34 3.8 3.6 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Hydrolase_6 PF13344.6 ORX93996.1 - 7.2e-18 64.6 0.0 1.8e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX93996.1 - 9.1e-12 44.9 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORX93996.1 - 0.00031 21.1 0.1 0.018 15.3 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORX93996.1 - 0.0042 17.2 0.0 0.65 10.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF732 PF05305.14 ORX93996.1 - 0.0061 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF732) Ldh_1_N PF00056.23 ORX93997.1 - 3.1e-28 98.6 0.3 5.9e-28 97.7 0.3 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93997.1 - 5.4e-22 78.5 0.0 8.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORX93998.1 - 1.3e-36 125.8 1.6 2.5e-36 124.9 1.6 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93998.1 - 1.3e-22 80.5 0.0 2.4e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORX93998.1 - 0.0016 18.1 1.4 0.017 14.7 0.6 2.5 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORX93998.1 - 0.019 15.6 1.3 0.1 13.2 0.5 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORX93998.1 - 0.027 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX93998.1 - 0.041 14.2 0.3 0.068 13.4 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 ORX93998.1 - 0.071 13.0 0.2 0.071 13.0 0.2 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORX93998.1 - 0.082 12.5 1.1 0.19 11.3 1.1 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 ORX93998.1 - 0.099 12.2 0.6 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 ORX93998.1 - 4.5 6.8 5.1 29 4.1 3.3 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Ldh_1_N PF00056.23 ORX93999.1 - 4e-29 101.5 0.5 7.8e-29 100.6 0.5 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX93999.1 - 3.9e-23 82.2 0.0 6.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain CBM9_1 PF06452.11 ORX94000.1 - 1.5e-11 44.6 0.1 3e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like AAA_2 PF07724.14 ORX94001.1 - 2.9e-52 177.2 0.0 7.7e-50 169.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORX94001.1 - 4.3e-36 123.0 2.2 4.3e-36 123.0 2.2 2.8 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 ORX94001.1 - 6.8e-29 101.0 0.6 7.1e-15 55.6 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORX94001.1 - 6.8e-21 74.1 2.4 1.9e-20 72.7 0.4 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORX94001.1 - 2.2e-19 69.8 0.6 4.3e-12 46.2 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX94001.1 - 4.2e-13 50.0 11.6 6e-07 30.0 0.0 5.2 3 3 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 ORX94001.1 - 3.2e-10 40.4 0.6 0.0022 18.3 0.0 4.3 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 ORX94001.1 - 7.9e-09 35.4 0.0 4.2e-05 23.3 0.0 3.0 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORX94001.1 - 1e-07 31.6 0.0 0.00067 19.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORX94001.1 - 1.8e-07 31.1 0.0 0.027 14.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 ORX94001.1 - 3.2e-07 30.5 3.1 0.31 10.9 0.1 4.5 3 2 1 5 5 5 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORX94001.1 - 8.8e-07 29.0 0.3 0.11 12.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 ORX94001.1 - 8.9e-07 28.5 2.2 0.11 11.9 0.0 4.5 3 1 1 4 4 4 1 Bacterial TniB protein RuvB_N PF05496.12 ORX94001.1 - 1e-05 25.4 5.4 0.061 13.1 0.0 4.9 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORX94001.1 - 2.6e-05 24.8 2.0 0.14 12.7 0.0 4.0 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 ORX94001.1 - 3.1e-05 24.0 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 ORX94001.1 - 3.9e-05 24.0 0.1 0.15 12.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 ORX94001.1 - 8.3e-05 22.8 0.0 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 ORX94001.1 - 0.00013 21.8 0.1 0.091 12.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ORX94001.1 - 0.00016 21.9 0.0 0.35 11.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORX94001.1 - 0.0002 21.6 3.7 2.9 8.1 0.0 4.4 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORX94001.1 - 0.00047 20.1 0.1 0.85 9.5 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase Zeta_toxin PF06414.12 ORX94001.1 - 0.00056 19.2 0.5 0.14 11.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 ORX94001.1 - 0.00057 19.3 0.1 0.8 9.0 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORX94001.1 - 0.0008 19.4 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ORX94001.1 - 0.00087 18.9 5.3 0.081 12.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain DNA_pol3_delta2 PF13177.6 ORX94001.1 - 0.0014 18.4 0.0 0.37 10.6 0.0 3.3 4 0 0 4 4 3 1 DNA polymerase III, delta subunit AAA_8 PF12780.7 ORX94001.1 - 0.0025 17.2 0.0 0.59 9.4 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 DUF815 PF05673.13 ORX94001.1 - 0.0027 16.9 0.1 1.4 8.0 0.0 3.2 3 1 0 3 3 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 ORX94001.1 - 0.0029 17.6 0.0 0.55 10.2 0.0 3.3 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX94001.1 - 0.0044 17.4 0.3 0.18 12.1 0.1 3.1 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORX94001.1 - 0.0046 16.7 0.0 5.9 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain EzrA PF06160.12 ORX94001.1 - 0.0048 15.1 11.5 0.0081 14.4 11.5 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SRP54 PF00448.22 ORX94001.1 - 0.0062 16.2 0.0 2.9 7.5 0.0 2.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORX94001.1 - 0.0073 16.0 0.0 3.9 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX94001.1 - 0.0089 16.0 0.1 3.2 7.6 0.0 3.2 3 0 0 3 3 3 1 NTPase PhoH PF02562.16 ORX94001.1 - 0.011 15.3 0.0 0.95 8.9 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 ORX94001.1 - 0.015 15.8 0.9 1.5 9.3 0.0 3.3 3 0 0 3 3 3 0 ABC transporter DUF87 PF01935.17 ORX94001.1 - 0.024 14.7 5.1 0.36 10.9 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain DnaB_C PF03796.15 ORX94001.1 - 0.044 13.1 0.4 2 7.7 0.0 2.8 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain AAA_29 PF13555.6 ORX94001.1 - 0.061 13.1 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 ORX94001.1 - 0.064 12.2 0.0 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Ras PF00071.22 ORX94001.1 - 0.14 11.7 0.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 Ras family BLOC1_2 PF10046.9 ORX94001.1 - 0.92 9.9 9.5 0.44 10.9 5.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cob_adeno_trans PF01923.18 ORX94001.1 - 1 9.5 4.0 1.1 9.4 1.9 2.2 2 0 0 2 2 1 0 Cobalamin adenosyltransferase AAA_23 PF13476.6 ORX94001.1 - 1.4 9.4 0.0 1.4 9.4 0.0 4.0 3 1 0 3 3 2 0 AAA domain V_ATPase_I PF01496.19 ORX94001.1 - 2.3 6.0 3.3 3 5.6 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.13 ORX94001.1 - 9.7 6.1 7.7 2.7 7.9 3.1 2.2 1 1 1 2 2 2 0 Aphid transmission protein AAA_2 PF07724.14 ORX94002.1 - 3.5e-52 177.0 0.1 1.1e-49 168.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORX94002.1 - 5.8e-36 122.6 2.2 5.8e-36 122.6 2.2 3.1 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 ORX94002.1 - 1.2e-28 100.2 0.6 9.9e-15 55.1 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORX94002.1 - 2.2e-20 72.5 0.3 2.2e-20 72.5 0.3 3.1 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORX94002.1 - 4.3e-19 68.9 0.4 5.9e-12 45.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 ORX94002.1 - 1.7e-13 50.4 1.8 1.4e-05 25.1 0.8 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 ORX94002.1 - 5.5e-12 46.4 14.0 7.9e-07 29.6 0.0 5.4 4 3 1 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 ORX94002.1 - 1e-09 38.8 1.5 0.003 17.8 0.0 4.6 4 1 0 4 4 2 2 AAA domain Sigma54_activat PF00158.26 ORX94002.1 - 1.5e-08 34.5 0.0 5.9e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORX94002.1 - 1.7e-07 30.9 0.0 0.00088 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORX94002.1 - 3.1e-07 30.3 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 ORX94002.1 - 6.1e-07 29.6 2.7 0.38 10.6 0.1 4.4 3 2 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORX94002.1 - 2e-06 27.9 0.3 0.15 12.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 ORX94002.1 - 2.2e-06 27.2 2.2 0.15 11.5 0.0 4.6 3 1 1 4 4 4 1 Bacterial TniB protein RuvB_N PF05496.12 ORX94002.1 - 2.2e-05 24.2 5.7 0.08 12.7 0.0 5.1 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORX94002.1 - 3e-05 24.2 0.0 0.16 12.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ORX94002.1 - 4.2e-05 24.1 1.8 0.2 12.2 0.0 4.0 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 ORX94002.1 - 4.2e-05 23.5 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 ORX94002.1 - 5.5e-05 23.5 0.0 0.2 12.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.11 ORX94002.1 - 0.00023 21.0 0.1 0.12 12.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ORX94002.1 - 0.00026 21.2 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORX94002.1 - 0.0004 20.7 3.3 3.7 7.8 0.0 4.4 3 1 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 ORX94002.1 - 0.00062 19.7 0.3 1.1 9.1 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase Zeta_toxin PF06414.12 ORX94002.1 - 0.001 18.4 1.5 0.18 11.0 0.0 3.8 4 0 0 4 4 4 1 Zeta toxin Mg_chelatase PF01078.21 ORX94002.1 - 0.0012 18.2 0.1 1.1 8.6 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORX94002.1 - 0.0013 18.7 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 ORX94002.1 - 0.0028 17.5 0.1 0.11 12.2 0.0 3.2 2 1 0 2 2 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.6 ORX94002.1 - 0.0041 16.7 6.8 0.11 12.1 0.0 3.9 5 0 0 5 5 3 1 AAA domain ResIII PF04851.15 ORX94002.1 - 0.0054 16.8 0.0 0.73 9.8 0.0 3.3 2 1 0 3 3 2 1 Type III restriction enzyme, res subunit EzrA PF06160.12 ORX94002.1 - 0.0058 14.9 11.5 0.011 14.0 11.5 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_30 PF13604.6 ORX94002.1 - 0.007 16.1 0.0 7.6 6.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX94002.1 - 0.0074 16.6 0.3 0.28 11.5 0.1 3.1 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.22 ORX94002.1 - 0.0088 15.7 0.0 3.7 7.1 0.0 3.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORX94002.1 - 0.011 15.5 0.0 5.2 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX94002.1 - 0.016 15.1 0.1 4.1 7.3 0.0 3.2 3 0 0 3 3 2 0 NTPase PhoH PF02562.16 ORX94002.1 - 0.018 14.5 0.0 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein DUF87 PF01935.17 ORX94002.1 - 0.028 14.5 4.8 0.47 10.5 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 ORX94002.1 - 0.029 14.9 1.1 2.1 8.9 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_6 PF12774.7 ORX94002.1 - 0.062 12.3 0.1 0.57 9.1 0.0 2.4 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 ORX94002.1 - 0.1 12.4 0.0 21 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX94002.1 - 2 8.9 0.0 2 8.9 0.0 4.3 4 1 0 4 4 2 0 AAA domain BLOC1_2 PF10046.9 ORX94002.1 - 3.1 8.1 10.7 0.54 10.6 5.0 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipase_3 PF01764.25 ORX94003.1 - 4.2e-34 117.5 0.0 9e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX94003.1 - 3.1e-05 23.6 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ORX94003.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 ORX94003.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX94003.1 - 0.0038 17.9 0.0 0.0046 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORX94003.1 - 0.09 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 ORX94003.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase RSN1_7TM PF02714.15 ORX94004.1 - 3.3e-67 226.7 30.7 4.2e-67 226.3 30.7 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORX94004.1 - 1.2e-09 38.6 0.0 1.8e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Sensor PF13796.6 ORX94004.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.6 2 1 1 3 3 3 0 Putative sensor PP2C PF00481.21 ORX94005.1 - 1.2e-41 143.1 0.0 1.5e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORX94005.1 - 0.001 19.0 0.1 2 8.3 0.0 3.2 3 1 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) DAP3 PF10236.9 ORX94006.1 - 2.5e-57 194.4 0.8 3.7e-57 193.9 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 ORX94006.1 - 3.9e-09 36.8 0.0 6.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ORX94006.1 - 1.1e-08 35.7 0.0 1.7e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORX94006.1 - 0.00013 22.4 0.1 0.0021 18.5 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX94006.1 - 0.00079 19.7 0.2 0.0037 17.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORX94006.1 - 0.012 15.5 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 ORX94006.1 - 0.018 14.6 0.5 0.14 11.7 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORX94006.1 - 0.019 15.0 0.1 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 ORX94006.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Glyco_hydro_46 PF01374.18 ORX94007.1 - 1.8e-27 96.4 0.0 2e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 DUF1640 PF07798.11 ORX94008.1 - 2.3e-44 151.5 9.5 2.5e-44 151.4 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 ORX94008.1 - 0.00015 21.9 5.2 0.00057 20.1 1.9 2.6 2 1 0 2 2 2 1 Homeobox associated leucine zipper DivIC PF04977.15 ORX94008.1 - 0.0055 16.5 10.7 0.044 13.6 2.7 2.7 2 1 0 2 2 2 2 Septum formation initiator KASH_CCD PF14662.6 ORX94008.1 - 0.0084 16.0 10.5 0.27 11.0 0.9 2.3 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH XhlA PF10779.9 ORX94008.1 - 0.0098 16.1 5.9 0.062 13.5 0.2 2.3 2 0 0 2 2 2 1 Haemolysin XhlA FlaC_arch PF05377.11 ORX94008.1 - 0.028 14.8 6.5 5 7.6 0.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Lzipper-MIP1 PF14389.6 ORX94008.1 - 0.04 14.2 7.7 0.57 10.5 4.4 3.0 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 YojJ PF10372.9 ORX94008.1 - 0.041 14.0 5.3 0.083 13.0 0.7 2.4 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus HMMR_C PF15908.5 ORX94008.1 - 0.044 14.1 5.7 0.23 11.7 0.2 2.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal TolA_bind_tri PF16331.5 ORX94008.1 - 0.05 13.7 4.5 2.4 8.3 0.1 2.5 1 1 0 2 2 2 0 TolA binding protein trimerisation Mt_ATP-synt_D PF05873.12 ORX94008.1 - 0.063 13.1 3.8 0.39 10.6 0.3 2.0 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) HlyD_2 PF12700.7 ORX94008.1 - 0.1 11.3 10.6 0.43 9.3 2.6 2.0 1 1 1 2 2 2 0 HlyD family secretion protein Fungal_TACC PF12709.7 ORX94008.1 - 0.16 12.5 7.2 0.31 11.5 1.8 2.4 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_MLP1_2 PF07926.12 ORX94008.1 - 0.21 11.6 11.8 0.73 9.9 3.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein JAKMIP_CC3 PF16034.5 ORX94008.1 - 0.23 11.4 10.1 0.71 9.8 10.1 1.8 1 1 0 1 1 1 0 JAKMIP CC3 domain Uso1_p115_C PF04871.13 ORX94008.1 - 0.45 10.9 9.4 0.67 10.3 3.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 ORX94008.1 - 0.49 11.1 8.3 8.7 7.0 6.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA GreA_GreB_N PF03449.15 ORX94008.1 - 0.71 10.1 9.0 0.91 9.7 6.5 2.3 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal DUF2508 PF10704.9 ORX94008.1 - 0.9 9.8 7.0 1.5 9.1 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) YlqD PF11068.8 ORX94008.1 - 1.1 9.6 10.8 1.6e+02 2.6 10.9 2.0 1 1 0 1 1 1 0 YlqD protein BST2 PF16716.5 ORX94008.1 - 1.4 9.5 9.8 1.3 9.6 2.1 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 bZIP_2 PF07716.15 ORX94008.1 - 2.2 8.4 11.1 6.7 6.9 0.1 3.4 3 1 0 3 3 3 0 Basic region leucine zipper Spc24 PF08286.11 ORX94008.1 - 9.8 6.5 8.8 10 6.4 0.7 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 OSCP PF00213.18 ORX94009.1 - 4.9e-50 170.0 4.5 5.7e-50 169.8 4.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit EMP24_GP25L PF01105.24 ORX94009.1 - 0.076 12.9 0.2 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PX PF00787.24 ORX94010.1 - 6.7e-28 96.9 0.1 8.5e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 PX domain NAD_Gly3P_dh_N PF01210.23 ORX94011.1 - 1.3e-45 155.2 0.1 1.8e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORX94011.1 - 3.3e-39 134.4 0.0 7.2e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus CBM_20 PF00686.19 ORX94012.1 - 4.9e-09 36.0 0.0 8.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain Kelch_2 PF07646.15 ORX94012.1 - 0.11 12.5 0.6 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Kelch motif LCD1 PF09798.9 ORX94012.1 - 0.13 10.8 1.5 0.16 10.4 1.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3498 PF12004.8 ORX94012.1 - 1.2 8.3 5.3 1.6 7.8 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Ufd2P_core PF10408.9 ORX94013.1 - 3.2e-221 736.3 16.7 4.1e-221 735.9 16.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 ORX94013.1 - 4.7e-28 97.2 2.9 1.1e-27 96.0 1.2 2.4 2 0 0 2 2 2 1 U-box domain Motile_Sperm PF00635.26 ORX94014.1 - 1.7e-25 89.0 0.1 3e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 ORX94014.1 - 0.00017 21.8 1.2 0.00085 19.5 0.1 2.2 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Cep57_CLD PF14073.6 ORX94014.1 - 0.0056 16.7 5.3 0.013 15.6 5.3 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 PRKG1_interact PF15898.5 ORX94014.1 - 1.1 10.1 7.2 0.96 10.4 5.1 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4193 PF13834.6 ORX94014.1 - 1.8 9.1 4.2 2.7 8.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4193) RGS PF00615.19 ORX94015.1 - 1.7e-14 54.1 3.2 4e-14 52.9 3.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Striatin PF08232.12 ORX94015.1 - 0.7 10.5 8.3 0.15 12.7 4.7 1.6 2 0 0 2 2 2 0 Striatin family EFF-AFF PF14884.6 ORX94017.1 - 0.033 12.3 0.0 0.044 11.9 0.0 1.2 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Sigma70_r4_2 PF08281.12 ORX94017.1 - 0.061 13.0 0.4 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DUF5409 PF17421.2 ORX94017.1 - 0.098 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5409) Arrestin_C PF02752.22 ORX94018.1 - 8.7e-15 55.4 0.9 3.3e-13 50.2 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX94018.1 - 3.6e-08 33.6 0.0 9.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX94018.1 - 0.0017 18.1 0.3 0.15 11.8 0.0 2.4 1 1 0 2 2 2 2 Arrestin_N terminal like WD40 PF00400.32 ORX94019.1 - 1.6e-71 234.4 39.6 3.3e-08 34.0 1.2 12.3 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.11 ORX94019.1 - 1.3e-55 187.3 2.0 2.1e-55 186.6 2.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 ORX94019.1 - 1.9e-22 79.4 5.7 0.017 15.4 0.0 9.3 3 3 5 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX94019.1 - 2.6e-07 30.3 2.1 0.011 15.1 0.1 4.4 3 2 2 5 5 5 2 WD40-like domain BBS2_Mid PF14783.6 ORX94019.1 - 4.8e-06 26.6 0.5 14 5.8 0.0 6.6 7 2 2 9 9 9 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 ORX94019.1 - 0.00012 21.2 11.7 0.045 12.7 0.3 6.1 2 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 ORX94019.1 - 0.00047 19.0 6.9 0.28 9.9 0.0 6.4 2 2 5 7 7 7 1 Nup133 N terminal like Nup160 PF11715.8 ORX94019.1 - 0.00076 18.3 17.2 3.8 6.0 0.0 7.8 5 4 3 9 9 9 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORX94019.1 - 0.0021 17.4 0.7 1.8 7.9 0.0 3.2 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal UTP15_C PF09384.10 ORX94019.1 - 0.0031 17.2 0.9 0.0058 16.3 0.9 1.4 1 0 0 1 1 1 1 UTP15 C terminal Cytochrom_D1 PF02239.16 ORX94019.1 - 0.029 12.9 2.1 0.083 11.4 0.1 2.7 3 1 0 3 3 3 0 Cytochrome D1 heme domain Pox_TAP PF03355.14 ORX94019.1 - 0.03 13.9 0.4 0.08 12.5 0.4 1.7 1 0 0 1 1 1 0 Viral Trans-Activator Protein Utp12 PF04003.12 ORX94019.1 - 0.061 13.6 0.3 0.15 12.4 0.3 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF5434 PF17502.2 ORX94020.1 - 0.088 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5434) DUF2244 PF10003.9 ORX94020.1 - 0.093 12.4 1.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Wzz PF02706.15 ORX94020.1 - 0.14 12.5 0.5 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Chain length determinant protein S_4TM PF18159.1 ORX94020.1 - 0.18 11.1 0.1 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain MatE PF01554.18 ORX94021.1 - 1.6e-61 206.7 30.1 2.4e-34 118.3 6.0 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 ORX94021.1 - 2.7e-07 30.8 5.1 2.7e-07 30.8 5.1 3.7 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Lipase_3 PF01764.25 ORX94022.1 - 1.3e-34 119.1 0.0 2.4e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX94022.1 - 5e-06 26.2 0.1 2.4e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ORX94022.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORX94022.1 - 0.005 17.5 0.0 0.0058 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX94022.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORX94022.1 - 0.098 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 ORX94022.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 ORX94022.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORX94022.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX94022.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 ORX94038.1 - 1.8e-98 330.4 30.5 2.1e-98 330.1 30.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94038.1 - 4.6e-18 65.3 56.9 8.1e-17 61.2 29.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Thaumatin PF00314.17 ORX94040.1 - 9.2e-70 234.6 11.6 1e-69 234.4 11.6 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORX94040.1 - 0.23 10.7 0.9 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase Ribosomal_S30 PF04758.14 ORX94041.1 - 4.1e-29 100.6 9.6 4.4e-29 100.4 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DnaJ PF00226.31 ORX94042.1 - 1.9e-18 66.3 0.8 6.1e-18 64.7 0.8 2.0 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 ORX94042.1 - 1.3e-16 61.4 6.7 1.3e-16 61.4 6.7 3.0 2 1 0 2 2 2 1 Ribosome-associated complex head domain TrmO_C PF18389.1 ORX94042.1 - 0.11 12.6 0.7 0.38 10.9 0.7 1.9 1 0 0 1 1 1 0 TrmO C-terminal domain CemA PF03040.14 ORX94042.1 - 5.3 6.9 6.3 8.5 6.2 6.3 1.3 1 0 0 1 1 1 0 CemA family CBFB_NFYA PF02045.15 ORX94043.1 - 8.9e-30 103.1 9.7 1e-29 102.9 9.7 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF4739 PF15893.5 ORX94043.1 - 0.15 11.6 0.2 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) DUF5543 PF17697.1 ORX94043.1 - 0.32 11.3 1.3 0.38 11.1 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5543) MTP18 PF10558.9 ORX94044.1 - 2.6e-61 206.5 4.3 1.9e-30 106.0 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Velvet PF11754.8 ORX94045.1 - 0.0013 18.7 5.1 0.0016 18.4 5.1 1.1 1 0 0 1 1 1 1 Velvet factor DUF908 PF06012.12 ORX94045.1 - 0.0019 17.7 5.5 0.0023 17.4 5.5 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) SARS_X4 PF08779.10 ORX94045.1 - 0.027 14.6 1.6 0.054 13.7 1.5 1.6 1 1 0 1 1 1 0 SARS coronavirus X4 like Macoilin PF09726.9 ORX94045.1 - 0.04 12.5 9.5 0.04 12.5 9.5 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 ORX94045.1 - 0.063 12.5 2.9 0.098 11.9 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AF-4 PF05110.13 ORX94045.1 - 0.24 9.4 19.7 0.27 9.3 19.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Spore_coat_CotO PF14153.6 ORX94045.1 - 1.1 9.1 4.6 1.5 8.7 4.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Menin PF05053.13 ORX94045.1 - 1.2 7.4 9.4 1.4 7.2 9.4 1.0 1 0 0 1 1 1 0 Menin PPP4R2 PF09184.11 ORX94045.1 - 1.5 8.4 11.0 1.9 8.0 11.0 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 ORX94045.1 - 3.1 6.5 9.4 4 6.1 9.4 1.1 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 ORX94045.1 - 3.8 6.4 11.7 4.5 6.1 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Apt1 PF10351.9 ORX94045.1 - 5.6 5.7 14.3 7.2 5.3 14.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 ORX94045.1 - 6.3 5.0 17.3 7 4.8 17.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ank_4 PF13637.6 ORX94046.1 - 2.1e-13 50.5 0.9 2.6e-06 27.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX94046.1 - 3.9e-13 49.3 0.3 4.1e-05 23.8 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX94046.1 - 8.7e-11 42.3 0.1 2.3e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX94046.1 - 6.9e-10 38.9 0.5 0.00016 22.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORX94046.1 - 5.4e-09 35.6 0.1 0.011 16.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Clathrin PF00637.20 ORX94046.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.8 1 1 0 1 1 1 0 Region in Clathrin and VPS Beta-Casp PF10996.8 ORX94047.1 - 1.6e-23 83.1 0.0 6e-23 81.2 0.0 2.0 2 1 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 ORX94047.1 - 7e-19 67.5 0.0 2.3e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 ORX94047.1 - 1.6e-09 37.5 0.2 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain GPI-anchored PF10342.9 ORX94048.1 - 2.1e-06 28.4 0.0 2.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WES_acyltransf PF03007.16 ORX94049.1 - 1.1e-27 97.5 0.0 2.6e-27 96.3 0.0 1.7 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ORX94049.1 - 1.2e-20 73.9 0.0 2.2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 ORX94049.1 - 1.2e-10 40.7 0.6 1.1e-09 37.5 0.4 1.9 2 0 0 2 2 2 1 Condensation domain PPR_2 PF13041.6 ORX94052.1 - 1.2e-130 425.6 35.7 8.1e-16 58.0 0.3 20.7 7 4 15 23 23 23 17 PPR repeat family PPR PF01535.20 ORX94052.1 - 3.5e-99 318.4 31.2 1.4e-06 28.1 0.1 23.4 24 0 0 24 24 24 16 PPR repeat PPR_3 PF13812.6 ORX94052.1 - 2e-80 264.8 28.1 3.4e-08 33.4 0.4 14.8 5 3 11 19 19 18 16 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX94052.1 - 1e-72 239.5 13.8 6.3e-07 29.0 0.0 18.4 19 0 0 19 19 19 13 PPR repeat PPR_long PF17177.4 ORX94052.1 - 5.7e-64 215.4 20.3 1.5e-17 63.7 1.2 9.6 1 1 9 10 10 10 9 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORX94052.1 - 3.3e-18 65.7 7.4 5.1e-06 25.6 0.0 6.7 5 1 3 8 8 8 4 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 ORX94052.1 - 3.9e-10 39.7 0.0 5 8.2 0.0 10.4 12 2 2 14 14 12 2 Tetratricopeptide repeat RPM2 PF08579.11 ORX94052.1 - 1.4e-09 38.4 19.1 0.33 11.4 1.4 10.8 6 4 3 9 9 9 2 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ORX94052.1 - 2e-09 37.3 8.9 1.9 8.4 0.1 8.9 4 2 3 9 9 9 1 Mitochondrial ATPase expression Clathrin PF00637.20 ORX94052.1 - 5.6e-07 29.5 23.3 0.096 12.6 0.3 7.5 2 2 6 8 8 8 3 Region in Clathrin and VPS TPR_19 PF14559.6 ORX94052.1 - 1.9e-06 28.2 9.5 0.52 10.8 0.0 7.7 8 3 3 11 11 9 1 Tetratricopeptide repeat ECSIT PF06239.11 ORX94052.1 - 3.2e-06 26.4 6.2 2 7.5 0.2 6.8 3 3 2 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway Vps39_1 PF10366.9 ORX94052.1 - 0.00023 21.4 10.3 12 6.2 0.0 6.7 4 2 2 6 6 5 0 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 ORX94052.1 - 0.0024 17.7 0.7 37 4.7 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 ORX94052.1 - 0.0049 17.0 11.5 1.5 9.0 0.4 4.7 5 1 1 6 6 6 2 Putative Mad3/BUB1 like region 1 protein Prp18 PF02840.15 ORX94052.1 - 0.0085 16.1 1.5 1.3 9.1 0.3 3.2 2 0 0 2 2 2 1 Prp18 domain Vps23_core PF09454.10 ORX94052.1 - 0.021 14.8 0.2 42 4.2 0.0 5.0 5 1 0 5 5 5 0 Vps23 core domain Endonuclease_5 PF04493.14 ORX94052.1 - 0.037 13.7 0.0 0.28 10.8 0.0 2.4 3 0 0 3 3 3 0 Endonuclease V BTAD PF03704.17 ORX94052.1 - 0.13 12.7 0.7 41 4.6 0.1 3.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain AIRS PF00586.24 ORX94052.1 - 0.13 12.9 0.0 7.5 7.3 0.0 3.3 2 1 1 3 3 3 0 AIR synthase related protein, N-terminal domain Mic1 PF07035.12 ORX94052.1 - 0.19 11.4 9.9 24 4.6 0.1 5.5 3 1 3 6 6 6 0 Colon cancer-associated protein Mic1-like DUF5578 PF17741.1 ORX94052.1 - 0.2 11.0 7.8 9.3 5.6 0.2 4.5 4 2 1 5 5 5 0 Family of unknown function (DUF5578) TPR_1 PF00515.28 ORX94052.1 - 0.5 10.3 12.8 4.2 7.3 0.0 7.3 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF1952 PF09189.10 ORX94053.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) NDUF_B4 PF07225.12 ORX94054.1 - 1.8e-07 31.1 0.0 2e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) zf-RanBP PF00641.18 ORX94055.1 - 5.8e-42 140.7 49.6 6.7e-10 38.1 3.5 5.2 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others Rubredoxin PF00301.20 ORX94055.1 - 2.6e-09 37.0 17.0 0.13 12.4 0.0 5.8 5 0 0 5 5 5 5 Rubredoxin DZR PF12773.7 ORX94055.1 - 0.0021 18.0 38.3 0.19 11.8 10.6 4.0 1 1 2 3 3 3 2 Double zinc ribbon zf-MIZ PF02891.20 ORX94055.1 - 0.066 13.0 18.0 3.5 7.5 0.1 5.2 5 0 0 5 5 5 0 MIZ/SP-RING zinc finger TackOD1 PF18551.1 ORX94055.1 - 0.17 11.5 38.0 0.31 10.7 1.0 4.9 4 1 0 4 4 4 0 Thaumarchaeal output domain 1 Vps36-NZF-N PF16988.5 ORX94055.1 - 3.1 7.3 37.8 0.42 10.1 0.8 5.7 5 2 0 5 5 5 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_ribbon_SprT PF17283.2 ORX94055.1 - 4.5 7.3 29.0 3.6 7.6 0.1 6.4 6 1 0 6 6 6 0 SprT-like zinc ribbon domain LRR_8 PF13855.6 ORX94056.1 - 8e-10 38.3 11.2 3.3e-06 26.8 4.8 4.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORX94056.1 - 2.4e-07 30.9 16.0 0.1 13.1 0.2 5.7 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX94056.1 - 0.00026 20.6 1.6 0.028 13.9 0.1 3.1 2 1 1 3 3 3 2 Leucine-rich repeat ABC_tran PF00005.27 ORX94057.1 - 2.1e-42 144.9 0.0 5.9e-20 72.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORX94057.1 - 3.1e-22 78.4 1.1 3.1e-22 78.4 1.1 3.1 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 ORX94057.1 - 7.8e-21 75.2 4.5 5.1e-05 23.2 0.3 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX94057.1 - 1.4e-11 44.3 0.7 0.00011 21.7 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX94057.1 - 5.4e-09 35.7 0.0 0.0035 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 ORX94057.1 - 6.3e-08 32.7 3.2 0.026 14.3 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 ORX94057.1 - 9.7e-07 29.5 7.7 0.038 14.5 0.0 3.7 3 1 0 4 4 4 2 AAA domain Dynamin_N PF00350.23 ORX94057.1 - 1.2e-06 28.6 0.1 0.0067 16.5 0.0 3.6 2 1 1 3 3 3 1 Dynamin family AAA_28 PF13521.6 ORX94057.1 - 1.9e-06 28.2 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX94057.1 - 1.2e-05 25.5 0.1 0.97 9.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 ORX94057.1 - 3.4e-05 24.1 0.0 0.18 12.0 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORX94057.1 - 4.5e-05 24.0 0.0 0.27 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX94057.1 - 4.7e-05 23.4 0.4 0.11 12.4 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 ORX94057.1 - 5.8e-05 23.1 0.0 0.33 11.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.6 ORX94057.1 - 6.3e-05 23.4 0.0 0.014 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORX94057.1 - 7.6e-05 22.5 0.1 0.52 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORX94057.1 - 0.00018 22.0 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 ORX94057.1 - 0.0002 21.0 0.6 0.42 10.2 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.6 ORX94057.1 - 0.00026 21.0 0.0 1.2 9.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ORX94057.1 - 0.0025 17.6 0.0 0.84 9.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ORX94057.1 - 0.003 17.5 0.4 3 7.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 ORX94057.1 - 0.0031 17.1 0.0 0.79 9.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 ORX94057.1 - 0.0033 16.6 0.0 0.36 9.9 0.0 2.4 1 1 0 2 2 2 1 G-protein alpha subunit AAA PF00004.29 ORX94057.1 - 0.0033 17.8 0.0 3.7 8.0 0.1 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 ORX94057.1 - 0.0035 17.5 1.1 4.1 7.4 0.0 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain VirE PF05272.11 ORX94057.1 - 0.0046 16.7 0.1 4.6 6.9 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E RNA_helicase PF00910.22 ORX94057.1 - 0.009 16.4 0.4 3.8 8.0 0.0 2.8 3 0 0 3 3 2 1 RNA helicase MeaB PF03308.16 ORX94057.1 - 0.0096 14.9 0.0 2.1 7.3 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MukB PF04310.12 ORX94057.1 - 0.017 14.9 0.0 4.8 6.9 0.0 3.2 3 0 0 3 3 3 0 MukB N-terminal FtsK_SpoIIIE PF01580.18 ORX94057.1 - 0.02 14.2 0.0 0.62 9.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 ORX94057.1 - 0.027 14.2 0.2 7 6.3 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 ORX94057.1 - 0.032 14.2 0.2 5.7 7.0 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 ORX94057.1 - 0.045 13.2 0.0 3.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein SbcCD_C PF13558.6 ORX94057.1 - 0.046 14.0 0.2 3.1 8.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 ORX94057.1 - 0.056 12.6 0.1 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 ORX94057.1 - 0.059 13.1 0.2 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF948 PF06103.11 ORX94057.1 - 0.062 13.6 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NB-ARC PF00931.22 ORX94057.1 - 0.067 12.4 0.0 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 ORX94057.1 - 0.081 12.4 0.1 3.2 7.2 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Septin PF00735.18 ORX94057.1 - 0.084 12.1 0.0 6 6.0 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_13 PF13166.6 ORX94057.1 - 0.093 11.4 2.8 17 3.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.21 ORX94057.1 - 0.11 12.6 1.3 29 4.6 0.0 3.4 4 0 0 4 4 3 0 MutS domain V AAA_5 PF07728.14 ORX94057.1 - 0.11 12.5 0.4 5.1 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 ORX94057.1 - 0.12 12.6 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORX94057.1 - 0.18 11.4 0.3 8.2 6.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.8 ORX94057.1 - 0.18 9.3 2.2 0.91 6.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Ribosomal_L2_C PF03947.18 ORX94058.1 - 3.7e-49 166.1 3.1 5.8e-49 165.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORX94058.1 - 5.1e-16 58.4 0.0 1.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cupin_8 PF13621.6 ORX94059.1 - 7.9e-32 110.9 0.0 1.2e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORX94059.1 - 1.5e-09 37.7 0.7 1.4e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 ORX94059.1 - 5.7e-05 23.5 0.0 0.0002 21.8 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ORX94059.1 - 0.00099 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORX94059.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Cytokin_check_N PF10407.9 ORX94059.1 - 0.19 11.7 1.8 4 7.5 0.6 2.9 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Kinesin PF00225.23 ORX94060.1 - 1e-102 343.5 0.0 1e-102 343.5 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORX94060.1 - 3.3e-59 199.1 0.0 7.2e-59 198.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 ORX94060.1 - 0.015 14.2 35.7 0.042 12.7 10.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FPP PF05911.11 ORX94060.1 - 0.12 10.5 40.2 0.33 9.1 16.9 3.0 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil CALCOCO1 PF07888.11 ORX94060.1 - 0.23 10.3 36.1 0.4 9.5 36.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PspA_IM30 PF04012.12 ORX94060.1 - 0.78 9.3 31.6 8.9 5.8 1.8 3.8 1 1 2 3 3 3 0 PspA/IM30 family AAA_16 PF13191.6 ORX94060.1 - 0.93 9.9 0.0 0.93 9.9 0.0 3.2 2 2 0 2 2 2 0 AAA ATPase domain DUF1664 PF07889.12 ORX94060.1 - 4.8 7.2 22.2 7.3 6.7 5.0 4.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Rep_fac_C PF08542.11 ORX94061.1 - 1.7e-17 63.6 0.6 3.4e-17 62.6 0.6 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ORX94061.1 - 3e-17 63.3 0.0 8.5e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORX94061.1 - 1.6e-13 50.8 0.0 1.1e-10 41.5 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORX94061.1 - 7.3e-08 32.6 0.0 1.8e-07 31.2 0.0 1.7 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 ORX94061.1 - 6.9e-06 26.3 0.1 1.7e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 ORX94061.1 - 7.5e-06 26.4 0.1 0.00023 21.6 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORX94061.1 - 1.7e-05 24.6 0.0 9.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX94061.1 - 3.6e-05 24.1 0.0 0.0017 18.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORX94061.1 - 4.8e-05 23.3 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORX94061.1 - 0.00016 21.7 0.0 0.00055 20.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX94061.1 - 0.00046 20.0 0.0 0.0018 18.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORX94061.1 - 0.00088 19.6 0.0 0.0031 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORX94061.1 - 0.0014 19.0 0.0 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DNA_pol3_delta PF06144.13 ORX94061.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 ORX94061.1 - 0.0026 17.2 0.0 0.052 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORX94061.1 - 0.0027 16.9 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 ORX94061.1 - 0.0037 17.3 0.0 0.017 15.2 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 ORX94061.1 - 0.0077 16.2 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORX94061.1 - 0.0086 15.8 0.0 0.031 14.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORX94061.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORX94061.1 - 0.023 15.3 0.1 0.1 13.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORX94061.1 - 0.023 14.9 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORX94061.1 - 0.032 13.5 0.1 0.83 8.8 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49_C PF17856.1 ORX94061.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_23 PF13476.6 ORX94061.1 - 0.075 13.5 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ORX94061.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 ORX94061.1 - 0.12 11.8 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 ORX94061.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX94061.1 - 0.16 11.5 0.0 0.48 10.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ORX94061.1 - 0.22 11.3 1.3 3.3 7.4 0.0 2.7 2 1 0 3 3 3 0 DEAD/DEAH box helicase Ribosom_S12_S23 PF00164.25 ORX94062.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SHQ1 PF04925.15 ORX94063.1 - 3.9e-72 241.5 3.5 5.7e-72 241.0 3.5 1.2 1 0 0 1 1 1 1 SHQ1 protein MgtE_N PF03448.17 ORX94063.1 - 0.037 14.6 7.6 0.13 12.9 5.5 2.9 2 1 0 2 2 2 0 MgtE intracellular N domain Asp-B-Hydro_N PF05279.11 ORX94063.1 - 1.7 8.6 15.2 0.19 11.8 10.8 1.6 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PDE4_UCR PF18100.1 ORX94063.1 - 2.3 8.9 6.2 29 5.3 0.2 3.6 2 1 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) Malic_M PF03949.15 ORX94064.1 - 1.7e-86 289.7 0.0 2.2e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORX94064.1 - 6.6e-60 202.0 0.0 1e-59 201.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ORX94066.1 - 1.8e-86 289.6 0.0 2.5e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORX94066.1 - 3.2e-59 199.8 0.0 5.5e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NOG1_N PF17835.1 ORX94076.1 - 0.037 14.0 1.0 5 7.1 0.0 3.1 3 0 0 3 3 3 0 NOG1 N-terminal helical domain DAGAT PF03982.13 ORX94077.1 - 3.1e-100 334.9 0.0 3.9e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 ORX94077.1 - 0.14 11.8 2.8 0.19 11.5 1.4 1.9 2 0 0 2 2 2 0 Rer1 family S6OS1 PF15676.5 ORX94077.1 - 0.49 8.8 1.3 0.64 8.4 1.3 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family EI24 PF07264.11 ORX94078.1 - 2.1e-30 106.3 8.2 2.6e-30 106.0 8.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Mito_carr PF00153.27 ORX94079.1 - 2.3e-53 178.1 6.6 1.9e-23 82.2 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX94079.1 - 0.0097 15.1 2.2 0.14 11.3 0.2 2.8 2 1 1 3 3 3 1 Gammaproteobacterial serine protease AAA_33 PF13671.6 ORX94079.1 - 0.029 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.6 ORX94080.1 - 1.3e-162 527.9 35.9 3.1e-15 56.1 0.0 17.8 3 2 15 18 18 18 17 PPR repeat family PPR PF01535.20 ORX94080.1 - 7.2e-108 345.6 22.9 4.1e-07 29.8 0.0 19.4 20 0 0 20 20 20 17 PPR repeat PPR_3 PF13812.6 ORX94080.1 - 6.9e-97 317.5 19.6 1.9e-12 47.1 0.1 11.8 9 1 1 11 11 11 11 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX94080.1 - 6.8e-94 307.2 0.9 2.7e-09 36.6 0.0 18.6 19 0 0 19 19 19 14 PPR repeat PPR_long PF17177.4 ORX94080.1 - 1.9e-55 187.5 5.7 9.5e-11 41.5 0.0 6.7 2 1 5 7 7 7 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX94080.1 - 2.3e-21 76.4 16.1 0.0046 17.3 0.6 10.5 1 1 8 9 9 9 6 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ORX94080.1 - 5.8e-08 32.6 12.2 2.1 8.2 0.1 8.4 5 2 3 10 10 9 4 Mitochondrial ATPase expression MRP-S27 PF10037.9 ORX94080.1 - 8.1e-08 31.5 11.9 0.083 11.7 0.0 7.1 2 2 2 6 6 6 4 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 ORX94080.1 - 1.2e-06 28.9 0.0 24 6.1 0.0 8.9 10 3 2 12 12 7 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORX94080.1 - 2.3e-05 24.4 1.6 1 9.3 0.1 5.8 5 1 1 6 6 6 1 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 ORX94080.1 - 0.00012 21.9 3.3 26 5.2 0.0 7.8 10 0 0 10 10 8 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 ORX94080.1 - 0.00035 20.3 0.9 8.1 6.0 0.0 4.5 4 1 0 4 4 4 1 Rab-GTPase-TBC domain TPR_19 PF14559.6 ORX94080.1 - 0.00041 20.8 1.9 3.3 8.3 0.0 6.7 9 0 0 9 9 7 1 Tetratricopeptide repeat Sulfotransfer_4 PF17784.1 ORX94080.1 - 0.0013 18.6 0.1 0.36 10.6 0.0 2.9 2 0 0 2 2 2 1 Sulfotransferase domain BKACE PF05853.12 ORX94080.1 - 0.0033 16.8 3.6 1.6 7.9 0.0 4.4 3 2 1 5 5 5 1 beta-keto acid cleavage enzyme Inhibitor_I9 PF05922.16 ORX94080.1 - 0.0037 17.9 2.4 3.9 8.2 0.0 4.3 3 1 0 3 3 3 1 Peptidase inhibitor I9 Ribonuc_red_lgN PF00317.21 ORX94080.1 - 0.011 15.7 5.5 5.3 7.1 0.1 6.1 5 2 0 5 5 5 0 Ribonucleotide reductase, all-alpha domain RasGEF PF00617.19 ORX94080.1 - 0.79 9.9 8.3 11 6.2 0.3 3.4 2 1 0 2 2 2 0 RasGEF domain Clathrin PF00637.20 ORX94080.1 - 1.7 8.5 11.0 57 3.6 0.2 6.4 6 2 2 8 8 8 0 Region in Clathrin and VPS PPR_2 PF13041.6 ORX94081.1 - 1.7e-117 383.5 19.1 2.6e-16 59.5 0.0 11.5 3 1 8 11 11 11 11 PPR repeat family PPR_1 PF12854.7 ORX94081.1 - 6.3e-72 236.9 3.2 1.2e-07 31.3 0.0 13.2 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 ORX94081.1 - 1.2e-71 236.7 2.7 6.3e-13 48.6 0.0 8.5 6 2 2 8 8 8 8 Pentatricopeptide repeat domain PPR PF01535.20 ORX94081.1 - 6.2e-68 220.4 12.0 6.7e-07 29.1 0.0 13.7 14 0 0 14 14 14 10 PPR repeat PPR_long PF17177.4 ORX94081.1 - 2.1e-32 112.2 0.0 5.3e-10 39.0 0.0 5.4 1 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX94081.1 - 2.5e-09 37.6 4.5 0.19 12.1 0.1 7.3 2 1 4 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX94081.1 - 3e-09 36.3 0.5 0.0002 20.4 0.0 3.7 1 1 2 3 3 3 2 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 ORX94081.1 - 4.4e-06 26.5 1.1 0.15 11.9 0.0 5.5 3 3 2 5 5 5 1 Mitochondrial ATPase expression TPR_14 PF13428.6 ORX94081.1 - 0.0031 18.2 0.0 87 4.3 0.0 6.0 5 2 2 7 7 6 0 Tetratricopeptide repeat AEP1 PF17049.5 ORX94081.1 - 0.0034 16.5 0.1 0.91 8.5 0.0 3.2 2 1 0 3 3 3 1 ATPase expression protein 1 DUF615 PF04751.14 ORX94081.1 - 0.054 13.5 0.2 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF615) PX PF00787.24 ORX94081.1 - 0.083 12.9 1.2 0.81 9.7 0.0 2.7 3 0 0 3 3 3 0 PX domain Actin PF00022.19 ORX94082.1 - 1.9e-67 227.7 0.0 4e-38 131.1 0.0 2.3 2 1 0 2 2 2 2 Actin RNase_PH PF01138.21 ORX94083.1 - 1.7e-23 83.5 0.0 3.4e-23 82.6 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORX94083.1 - 6.7e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF4598 PF15370.6 ORX94084.1 - 7.6e-20 71.5 3.1 1.1e-19 70.9 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) 60KD_IMP PF02096.20 ORX94085.1 - 1.1e-19 70.9 1.9 4.6e-19 68.9 1.9 1.8 1 1 0 1 1 1 1 60Kd inner membrane protein RCC1 PF00415.18 ORX94086.1 - 2e-20 73.2 0.9 1.3e-07 32.2 0.0 5.7 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORX94086.1 - 5.1e-14 51.6 4.5 1e-06 28.4 0.1 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 ORX94087.1 - 2e-68 230.6 0.0 2.4e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94087.1 - 1.4e-52 178.6 0.0 1.9e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX94087.1 - 2.9e-09 36.2 0.0 6e-08 31.9 0.0 2.0 1 1 1 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORX94087.1 - 4.8e-08 32.7 0.0 3.1e-07 30.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX94087.1 - 0.00022 20.3 0.2 0.0031 16.5 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX94087.1 - 0.00074 19.5 0.0 0.0037 17.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX94087.1 - 0.0012 18.2 0.1 0.0021 17.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX94087.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX94087.1 - 0.031 13.9 0.1 0.068 12.8 0.0 1.6 1 1 1 2 2 2 0 RIO1 family Fasciclin PF02469.22 ORX94089.1 - 2.8e-38 131.0 1.3 1.6e-18 67.2 0.5 3.1 2 1 0 2 2 2 2 Fasciclin domain SR-25 PF10500.9 ORX94089.1 - 0.0052 16.4 12.9 0.0076 15.9 12.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med19 PF10278.9 ORX94089.1 - 1.2 9.0 12.6 2.4 8.1 12.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ORMDL PF04061.14 ORX94090.1 - 1.3e-51 174.0 3.9 1.5e-51 173.8 3.9 1.0 1 0 0 1 1 1 1 ORMDL family Bap31 PF05529.12 ORX94091.1 - 2.9e-39 134.0 5.5 4.3e-39 133.5 5.5 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ORX94091.1 - 6.4e-09 35.7 9.9 1.5e-08 34.5 9.9 1.6 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain AAA_23 PF13476.6 ORX94091.1 - 0.044 14.3 5.4 0.052 14.0 5.4 1.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORX94091.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PAS_3 PF08447.12 ORX94092.1 - 3.7e-05 23.9 0.1 0.001 19.3 0.0 2.3 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 ORX94092.1 - 0.00056 20.0 10.3 0.00056 20.0 10.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORX94092.1 - 0.0031 17.5 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold HMG_box PF00505.19 ORX94093.1 - 3e-08 34.0 0.1 7.5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX94093.1 - 6.3e-05 23.5 0.1 0.00021 21.8 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain DUF1390 PF07150.11 ORX94093.1 - 0.0052 16.5 0.3 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1390) DUF1353 PF07087.11 ORX94093.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) NAD_binding_4 PF07993.12 ORX94094.1 - 2.3e-72 243.3 0.0 4.7e-72 242.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ORX94094.1 - 1e-68 231.9 0.0 3e-68 230.4 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 ORX94094.1 - 6e-20 71.3 1.5 4.5e-19 68.4 1.5 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 ORX94094.1 - 7.3e-11 42.3 0.0 2.1e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ORX94094.1 - 3.7e-09 36.4 0.0 7.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX94094.1 - 7.5e-08 31.7 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 ORX94094.1 - 1.1e-07 32.7 0.0 3.9e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 ORX94095.1 - 3.3e-36 124.7 0.1 6.3e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX94095.1 - 1.7e-12 47.3 11.7 2.8e-12 46.5 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 ORX94096.1 - 8.4e-64 215.4 0.0 6.3e-63 212.6 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX94096.1 - 1.8e-11 43.5 0.0 4.5e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORX94096.1 - 5.2e-05 22.6 0.0 0.094 12.0 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ORX94096.1 - 9.8e-05 21.5 0.0 0.00043 19.4 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 ORX94096.1 - 9.9e-05 23.0 0.1 0.00049 20.8 0.0 2.1 1 1 2 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX94096.1 - 0.0011 18.7 0.0 0.0033 17.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX94096.1 - 0.015 14.8 0.0 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 ORX94096.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Questin_oxidase PF14027.6 ORX94097.1 - 5.5e-58 197.1 0.4 6.5e-58 196.9 0.4 1.0 1 0 0 1 1 1 1 Questin oxidase-like RhoGAP PF00620.27 ORX94097.1 - 0.18 11.6 0.0 0.52 10.1 0.0 1.7 2 0 0 2 2 2 0 RhoGAP domain Peptidase_M16_M PF16187.5 ORX94097.1 - 0.19 11.0 0.7 0.3 10.3 0.1 1.5 2 0 0 2 2 2 0 Middle or third domain of peptidase_M16 Questin_oxidase PF14027.6 ORX94098.1 - 2.3e-61 208.2 0.2 2.8e-61 208.0 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 ORX94099.1 - 1.2e-60 205.9 0.5 1.4e-60 205.7 0.5 1.0 1 0 0 1 1 1 1 Questin oxidase-like Glyco_hydro_53 PF07745.13 ORX94099.1 - 0.12 11.4 0.5 7.4 5.4 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 53 P4Ha_N PF08336.11 ORX94099.1 - 0.18 11.9 0.7 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cu_amine_oxid PF01179.20 ORX94113.1 - 6.8e-158 525.9 0.3 8.2e-158 525.6 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORX94113.1 - 4.2e-14 52.8 0.0 1.4e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORX94113.1 - 8.9e-07 29.1 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Hydrolase_4 PF12146.8 ORX94115.1 - 4.4e-11 42.5 0.1 3.1e-10 39.7 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX94115.1 - 4.5e-10 39.6 0.0 1.8e-08 34.4 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 ORX94115.1 - 0.0023 17.3 0.1 0.0042 16.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 ORX94115.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ORX94115.1 - 0.037 13.5 0.2 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORX94115.1 - 0.049 14.2 0.0 0.065 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 ORX94115.1 - 0.063 12.9 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Peptidase_S15 PF02129.18 ORX94115.1 - 0.16 11.6 0.0 16 5.0 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Dicty_CAR PF05462.11 ORX94117.1 - 0.00049 19.3 7.3 0.00075 18.7 7.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor SpoIIE PF07228.12 ORX94118.1 - 2.7e-13 50.3 0.0 4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORX94118.1 - 3.3e-05 23.6 0.0 0.00023 20.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ORX94118.1 - 0.00076 19.2 0.2 0.33 10.5 0.0 2.2 1 1 0 2 2 2 2 Protein phosphatase 2C Skp1 PF01466.19 ORX94119.1 - 1.6e-28 98.5 0.2 3.3e-28 97.5 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORX94119.1 - 5.7e-26 90.5 0.1 1.6e-25 89.1 0.1 1.8 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Mo25 PF08569.11 ORX94120.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Mo25-like ExoD PF06055.12 ORX94121.1 - 0.0053 16.2 0.3 0.0072 15.7 0.3 1.4 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD WD40 PF00400.32 ORX94122.1 - 5.5e-11 42.8 3.1 0.00026 21.7 0.1 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX94122.1 - 2.2e-10 40.7 0.0 0.048 14.0 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 ORX94122.1 - 4.9e-05 23.2 0.1 0.00011 22.0 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 ORX94122.1 - 6.3e-05 22.8 0.5 7.2 6.7 0.0 3.8 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 ORX94122.1 - 0.015 13.8 0.0 0.7 8.4 0.1 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 ORX94122.1 - 0.18 11.5 2.0 18 5.1 0.1 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Tim17 PF02466.19 ORX94123.1 - 4.1e-26 91.5 8.8 5.6e-26 91.1 8.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-C2H2 PF00096.26 ORX94124.1 - 1.2e-10 41.2 9.6 1.3e-06 28.5 2.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX94124.1 - 5.6e-10 39.2 13.7 4.9e-05 23.6 1.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX94124.1 - 4.8e-07 30.1 8.5 8.9e-05 23.0 1.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX94124.1 - 0.00022 21.1 2.0 0.00022 21.1 2.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 ORX94124.1 - 0.0012 18.7 6.4 0.0042 17.0 2.8 2.1 2 0 0 2 2 2 1 SprT-like zinc ribbon domain DUF3268 PF11672.8 ORX94124.1 - 0.0024 18.2 0.4 0.0025 18.1 0.4 1.1 1 0 0 1 1 1 1 zinc-finger-containing domain zf-DNA_Pol PF08996.10 ORX94124.1 - 0.009 15.8 0.2 0.0099 15.6 0.2 1.0 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-C2H2_jaz PF12171.8 ORX94124.1 - 0.011 16.1 0.2 0.023 15.0 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 ORX94124.1 - 0.011 15.8 1.3 2.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 ORX94124.1 - 0.014 15.8 2.3 0.061 13.8 0.1 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ORX94124.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORX94124.1 - 0.02 14.6 5.0 0.035 13.9 0.4 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 ORX94124.1 - 0.022 15.1 1.0 0.022 15.1 1.0 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORX94124.1 - 0.037 14.4 1.4 0.33 11.3 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORX94124.1 - 0.045 13.8 3.3 0.53 10.4 3.3 2.2 1 1 0 1 1 1 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 ORX94124.1 - 3.2 7.8 7.0 7.7 6.6 7.0 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Peptidase_S9 PF00326.21 ORX94125.1 - 0.031 13.7 0.0 0.036 13.5 0.0 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase family dUTPase PF00692.19 ORX94126.1 - 2.3e-43 147.0 0.0 3e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase CBFD_NFYB_HMF PF00808.23 ORX94127.1 - 4.5e-20 71.7 1.4 7.4e-20 71.0 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX94127.1 - 5.7e-19 68.8 0.3 9.2e-19 68.1 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 ORX94127.1 - 0.0053 17.0 0.3 0.0092 16.3 0.3 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Gin PF10764.9 ORX94129.1 - 0.063 13.2 2.8 1.6 8.7 0.2 2.9 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin 4HBT_3 PF13622.6 ORX94130.1 - 1.6e-60 205.5 0.0 1.8e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORX94130.1 - 5.8e-34 116.8 0.0 1.6e-26 92.7 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT PF03061.22 ORX94130.1 - 0.077 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily AMP-binding PF00501.28 ORX94131.1 - 7.2e-95 318.1 0.0 9.3e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX94131.1 - 2.8e-15 57.0 0.1 7.3e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lum_binding PF00677.17 ORX94131.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Lumazine binding domain DUF4745 PF15923.5 ORX94131.1 - 0.051 13.6 0.5 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) PAS PF00989.25 ORX94132.1 - 7.1e-05 22.8 0.0 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 ORX94132.1 - 0.0033 17.5 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX94132.1 - 0.091 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 PAS fold RCR PF12273.8 ORX94133.1 - 0.00082 20.0 0.2 0.0011 19.6 0.2 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CPSase_sm_chain PF00988.22 ORX94135.1 - 4.9e-48 162.2 0.0 9.9e-48 161.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORX94135.1 - 3.5e-43 147.6 0.0 4.7e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORX94135.1 - 0.0026 17.5 0.1 0.29 10.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 ORX94135.1 - 0.0033 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Pkinase PF00069.25 ORX94136.1 - 2.3e-72 243.5 0.0 3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94136.1 - 6.2e-34 117.4 0.0 8.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX94136.1 - 5.3e-10 39.1 0.0 7.7e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORX94136.1 - 0.00041 20.4 0.6 0.0012 18.9 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX94136.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX94136.1 - 0.003 16.4 0.0 0.032 13.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PHC2_SAM_assoc PF16616.5 ORX94136.1 - 0.24 12.2 4.1 0.44 11.4 4.1 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Forkhead PF00250.18 ORX94137.1 - 2.9e-30 104.3 0.4 3.2e-30 104.2 0.4 1.0 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 ORX94137.1 - 0.076 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 linker histone H1 and H5 family Glyco_tranf_2_3 PF13641.6 ORX94150.1 - 5e-32 111.6 0.2 6.6e-32 111.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX94150.1 - 3.5e-11 43.2 0.0 5.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX94150.1 - 1.7e-09 37.4 0.1 3.3e-09 36.4 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 ORX94150.1 - 0.00028 19.6 6.0 0.00071 18.3 6.1 1.4 1 1 0 1 1 1 1 Chitin synthase Fungal_TACC PF12709.7 ORX94151.1 - 4.4e-05 23.9 6.3 0.0054 17.1 2.5 2.7 2 0 0 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins Lzipper-MIP1 PF14389.6 ORX94151.1 - 0.00018 21.7 3.5 0.00083 19.6 3.5 2.2 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Lebercilin PF15619.6 ORX94151.1 - 0.0028 17.3 6.3 0.0054 16.4 6.3 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 ORX94151.1 - 0.0033 17.6 5.3 0.19 11.9 0.1 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 ORX94151.1 - 0.0067 16.5 6.3 0.018 15.1 6.3 1.7 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein FH2 PF02181.23 ORX94151.1 - 0.012 14.7 2.6 0.022 13.9 2.6 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF5595 PF18077.1 ORX94151.1 - 0.027 14.6 2.0 4.5 7.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF1664 PF07889.12 ORX94151.1 - 0.032 14.3 1.3 0.075 13.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORX94151.1 - 0.087 13.2 1.8 1 9.8 0.2 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 ORX94151.1 - 0.16 11.7 2.3 0.27 11.0 1.2 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1640 PF07798.11 ORX94151.1 - 0.21 11.6 5.7 0.39 10.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF5320 PF17253.2 ORX94151.1 - 0.37 11.9 1.6 2.5 9.2 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4200 PF13863.6 ORX94151.1 - 0.39 11.1 6.9 0.97 9.9 6.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.13 ORX94151.1 - 0.44 10.6 5.5 3.1 7.9 5.5 2.2 1 1 0 1 1 1 0 DivIVA protein Jnk-SapK_ap_N PF09744.9 ORX94151.1 - 0.61 10.3 7.9 2.1 8.5 7.9 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 ORX94151.1 - 0.75 10.3 8.6 3.7 8.1 8.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 ORX94151.1 - 0.8 9.5 7.5 1.4 8.7 1.7 2.4 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 ORX94151.1 - 1.7 8.8 8.6 1.4 9.0 0.8 3.1 3 0 0 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 ORX94151.1 - 6.2 7.1 7.8 3.4 7.9 2.8 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 ORX94151.1 - 6.3 7.0 9.9 29 4.8 9.5 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Mad3_BUB1_I PF08311.12 ORX94152.1 - 6.9e-45 152.0 0.1 1.2e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 ORX94152.1 - 2.8e-05 24.2 0.0 4.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Mad3_BUB1_II PF08171.11 ORX94152.1 - 0.0002 21.5 0.0 0.019 15.1 0.0 3.2 2 1 0 2 2 2 1 Mad3/BUB1 homology region 2 Arrestin_C PF02752.22 ORX94153.1 - 1.9e-11 44.5 0.5 1.3e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX94153.1 - 1.8e-10 41.1 0.0 6.5e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX94153.1 - 2.5e-06 27.3 0.0 6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Arrestin_N terminal like Spo0M PF07070.11 ORX94153.1 - 0.21 11.1 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 SpoOM protein DUF4203 PF13886.6 ORX94154.1 - 1.4e-43 148.9 45.8 1.7e-43 148.6 45.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF962 PF06127.11 ORX94154.1 - 0.68 10.1 6.7 0.28 11.3 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF962) DUF4203 PF13886.6 ORX94155.1 - 2.3e-46 158.0 42.9 3.1e-46 157.6 42.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SPC25 PF06703.11 ORX94155.1 - 0.14 11.9 0.2 0.14 11.9 0.2 3.2 1 1 2 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Mito_carr PF00153.27 ORX94156.1 - 1.3e-28 98.7 2.6 9.3e-15 54.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S27e PF01667.17 ORX94157.1 - 1.1e-29 101.8 4.9 1.4e-29 101.6 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORX94157.1 - 0.15 11.6 3.2 0.23 11.0 3.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 ORX94158.1 - 3.6e-14 52.5 11.7 1.5e-07 31.5 0.9 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX94158.1 - 6.3e-14 51.6 19.1 0.00014 22.1 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX94158.1 - 4.1e-11 42.7 17.8 0.0006 20.4 3.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 ORX94158.1 - 0.00027 21.2 10.3 0.25 11.8 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX94158.1 - 0.014 15.4 15.8 2 8.5 1.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 ORX94158.1 - 0.042 13.9 13.0 0.087 12.9 1.1 3.4 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_3rep PF18868.1 ORX94158.1 - 0.1 13.2 5.5 7.4 7.3 0.1 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORX94158.1 - 0.14 12.4 8.0 1.3 9.4 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 ORX94158.1 - 0.53 10.3 4.8 7.5 6.6 0.5 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_8 PF15909.5 ORX94158.1 - 0.67 10.3 6.8 1.9 8.8 5.9 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-MYST PF17772.1 ORX94158.1 - 0.73 9.5 3.8 44 3.8 0.3 3.5 2 1 1 3 3 3 0 MYST family zinc finger domain Endonuclease_7 PF02945.15 ORX94158.1 - 0.86 9.6 4.9 0.33 10.9 2.2 1.6 1 1 0 1 1 1 0 Recombination endonuclease VII zf-H2C2_5 PF13909.6 ORX94158.1 - 1.7 8.5 7.1 0.16 11.7 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORX94158.1 - 2.6 8.6 11.2 50 4.4 3.1 3.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 ORX94158.1 - 3.2 8.0 9.0 15 5.8 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger DUF4764 PF15961.5 ORX94158.1 - 9.1 4.8 7.4 0.34 9.6 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) UBN_AB PF14075.6 ORX94159.1 - 5.3e-26 91.7 2.7 5.3e-26 91.7 2.7 5.6 6 0 0 6 6 6 1 Ubinuclein conserved middle domain HUN PF08729.10 ORX94159.1 - 4.1e-08 33.1 1.7 1.1e-07 31.8 0.1 2.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Tetraspanin PF00335.20 ORX94160.1 - 2.6e-08 33.9 0.2 3.3e-08 33.5 0.2 1.1 1 0 0 1 1 1 1 Tetraspanin family EcsB PF05975.12 ORX94160.1 - 0.079 11.8 0.2 0.14 11.0 0.1 1.5 1 1 1 2 2 2 0 Bacterial ABC transporter protein EcsB FRG1 PF06229.12 ORX94161.1 - 1.1e-35 123.1 0.3 1.1e-35 123.1 0.3 1.7 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 ORX94161.1 - 1.9e-05 24.8 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Fascin domain Malic_M PF03949.15 ORX94162.1 - 1.9e-84 282.9 0.0 2.4e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORX94162.1 - 1.6e-60 204.0 0.0 2.5e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ORX94163.1 - 1.2e-85 286.9 0.0 6.4e-85 284.5 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 ORX94163.1 - 3.5e-60 202.9 0.0 5.7e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Endonuclease_NS PF01223.23 ORX94164.1 - 1.1e-66 225.0 0.0 1.3e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FlxA PF14282.6 ORX94166.1 - 0.099 12.6 5.1 0.88 9.6 0.1 2.6 2 0 0 2 2 2 0 FlxA-like protein RPN7 PF10602.9 ORX94166.1 - 0.1 12.3 1.3 0.22 11.2 1.3 1.5 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Nup54_57_C PF18570.1 ORX94166.1 - 0.14 11.7 0.8 0.36 10.4 0.8 1.7 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Leu_zip PF15294.6 ORX94166.1 - 0.16 11.5 10.7 0.23 10.9 10.7 1.2 1 0 0 1 1 1 0 Leucine zipper DUF2203 PF09969.9 ORX94166.1 - 0.32 11.7 5.0 4.2 8.1 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 ORX94166.1 - 3.2 8.2 5.5 1.1 9.7 0.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DMPK_coil PF08826.10 ORX94166.1 - 5 7.3 8.9 21 5.3 0.4 2.7 2 0 0 2 2 2 0 DMPK coiled coil domain like CBM_1 PF00734.18 ORX94168.1 - 0.17 11.8 0.6 7.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Fungal cellulose binding domain Trypan_PARP PF05887.11 ORX94169.1 - 3.2e-05 23.9 11.0 3.2e-05 23.9 11.0 1.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF1093 PF06486.11 ORX94169.1 - 0.013 16.2 0.3 2 9.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1093) LigD_N PF13298.6 ORX94169.1 - 0.096 13.0 0.0 12 6.2 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) Mito_fiss_reg PF05308.11 ORX94169.1 - 7.8 6.5 9.1 14 5.7 9.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Cu-oxidase_3 PF07732.15 ORX94175.1 - 3.3e-11 43.2 11.1 0.002 18.1 0.0 6.5 7 0 0 7 7 7 5 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX94175.1 - 5.9e-07 29.3 14.1 0.00035 20.3 4.6 5.7 5 1 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 ORX94175.1 - 0.0089 16.2 0.1 6.1 6.9 0.0 3.0 4 0 0 4 4 4 2 Multicopper oxidase Lipase_GDSL PF00657.22 ORX94176.1 - 5.5e-06 26.5 0.0 2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_3 PF01764.25 ORX94177.1 - 4.1e-34 117.5 0.0 6.5e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX94177.1 - 0.00052 19.7 0.1 0.0064 16.1 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX94177.1 - 0.0022 18.7 0.0 0.0026 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORX94177.1 - 0.0033 17.2 0.0 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX94177.1 - 0.0041 16.4 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ORX94177.1 - 0.037 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.13 ORX94177.1 - 0.067 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORX94177.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 ORX94177.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ORC3_N PF07034.11 ORX94178.1 - 9.6e-45 153.1 0.3 2.5e-44 151.7 0.3 1.7 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ORX94178.1 - 2e-33 115.4 3.9 6.4e-19 68.4 0.1 3.0 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Sybindin PF04099.12 ORX94179.1 - 8e-34 116.6 0.2 1.1e-33 116.2 0.2 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORX94179.1 - 8.8e-05 22.6 0.1 0.0001 22.4 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF5319 PF17252.2 ORX94179.1 - 0.029 14.6 0.1 0.063 13.5 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5319) DPM2 PF07297.12 ORX94180.1 - 3.3e-31 107.4 2.0 3.7e-31 107.3 2.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 ORX94180.1 - 0.00014 21.7 3.8 0.00017 21.5 3.8 1.1 1 0 0 1 1 1 1 PIG-P DUF3377 PF11857.8 ORX94180.1 - 1.7 8.6 4.2 0.51 10.3 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) RDD PF06271.12 ORX94180.1 - 3 8.1 7.6 18 5.5 7.0 1.9 1 1 0 1 1 1 0 RDD family DMRL_synthase PF00885.19 ORX94183.1 - 0.00082 19.2 0.0 9.6 6.0 0.0 3.2 3 0 0 3 3 3 3 6,7-dimethyl-8-ribityllumazine synthase CobS_N PF12556.8 ORX94183.1 - 0.0018 18.0 3.2 14 5.5 0.1 3.5 3 0 0 3 3 3 3 Cobaltochelatase CobS subunit N terminal CobS_N PF12556.8 ORX94184.1 - 0.077 12.7 0.4 8.6 6.2 0.1 2.6 2 0 0 2 2 2 0 Cobaltochelatase CobS subunit N terminal F-box-like PF12937.7 ORX94186.1 - 0.0001 22.1 0.2 0.0006 19.6 0.3 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORX94186.1 - 0.0022 18.4 8.6 2.2 8.8 0.0 5.0 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 ORX94187.1 - 1.9e-24 86.5 0.0 3.2e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 ORX94187.1 - 2.7e-07 30.8 0.5 0.0038 17.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 ORX94187.1 - 0.0062 15.9 0.3 0.15 11.3 0.6 2.5 1 1 0 1 1 1 1 Ecdysteroid kinase PEHE PF15275.6 ORX94189.1 - 0.0062 17.2 11.6 0.0062 17.2 11.6 3.7 2 2 1 3 3 3 1 PEHE domain DUF4785 PF16024.5 ORX94189.1 - 0.08 11.7 2.4 1.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4785) Mito_carr PF00153.27 ORX94190.1 - 8.5e-28 96.1 3.6 1.6e-11 44.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX94190.1 - 0.00096 18.4 0.7 0.0042 16.3 0.0 2.3 3 0 0 3 3 3 1 Gammaproteobacterial serine protease GHMP_kinases_N PF00288.26 ORX94191.1 - 5.2e-11 42.6 0.2 1.3e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX94191.1 - 0.00024 21.4 0.0 0.00069 19.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal ATP-synt PF00231.19 ORX94193.1 - 2.6e-78 263.6 6.1 2.9e-78 263.4 6.1 1.0 1 0 0 1 1 1 1 ATP synthase Ecl1 PF12855.7 ORX94194.1 - 7.3e-10 40.3 0.9 8.7e-10 40.0 0.9 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Ecl1 PF12855.7 ORX94195.1 - 8.2e-11 43.4 10.7 1e-10 43.1 10.7 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 ORX94195.1 - 0.011 15.7 0.9 0.011 15.7 0.9 1.9 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) C1_2 PF03107.16 ORX94195.1 - 0.045 14.1 4.1 0.092 13.1 4.1 1.6 1 0 0 1 1 1 0 C1 domain DUF1752 PF08550.10 ORX94196.1 - 1.3e-12 47.3 2.3 2.7e-12 46.3 2.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.8 ORX94196.1 - 0.053 12.9 0.2 0.053 12.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3295) Zn_clus PF00172.18 ORX94198.1 - 1.6e-05 24.9 15.9 2.7e-05 24.2 15.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adaptin_N PF01602.20 ORX94199.1 - 1.7e-119 399.8 0.3 2.1e-119 399.5 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORX94199.1 - 5.3e-13 49.3 1.1 8.7e-10 38.9 0.0 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORX94199.1 - 5.9e-06 26.1 0.1 0.41 11.0 0.1 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 ORX94199.1 - 1.2e-05 25.6 0.0 0.098 13.1 0.0 3.5 2 1 1 3 3 3 3 HEAT repeats AP3D1 PF06375.11 ORX94199.1 - 0.00059 20.1 6.4 0.12 12.6 3.2 2.3 1 1 1 2 2 2 2 AP-3 complex subunit delta-1 RTP1_C1 PF10363.9 ORX94199.1 - 0.15 12.3 0.0 13 6.0 0.0 2.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 TFIIE_alpha PF02002.17 ORX94201.1 - 2e-18 66.2 3.7 4.3e-18 65.1 3.7 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit Helo_like_N PF17111.5 ORX94201.1 - 0.014 14.7 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Zn-C2H2_12 PF18112.1 ORX94201.1 - 0.023 15.2 0.1 0.052 14.0 0.1 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Zn_Tnp_IS1595 PF12760.7 ORX94201.1 - 0.031 14.2 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 ORX94201.1 - 0.14 12.2 0.8 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C2H2_4 PF13894.6 ORX94201.1 - 0.25 12.3 1.1 5.1 8.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX94201.1 - 0.27 11.8 1.1 0.9 10.1 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Tim17 PF02466.19 ORX94202.1 - 6.5e-39 132.7 2.3 7.5e-39 132.5 2.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 ORX94203.1 - 4.7e-63 213.0 0.1 5.7e-63 212.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94203.1 - 5.3e-17 62.0 0.0 7.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX94203.1 - 2e-08 34.5 0.0 4.9e-06 26.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX94203.1 - 0.0077 15.0 0.1 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORX94203.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORX94203.1 - 0.017 14.7 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 ORX94203.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 ABC1 family FUSC PF04632.12 ORX94223.1 - 4.9e-16 58.4 6.2 3.4e-13 49.0 0.0 2.9 2 1 1 3 3 3 3 Fusaric acid resistance protein family ArAE_2 PF10334.9 ORX94223.1 - 5.5e-16 59.1 0.1 1.2e-12 48.2 0.0 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORX94223.1 - 6.2e-15 55.2 10.1 1.1e-12 47.7 0.2 2.5 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORX94223.1 - 1.3e-14 54.4 9.0 1.3e-14 54.4 9.0 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 ORX94223.1 - 9.2e-14 51.1 5.0 9.2e-14 51.1 5.0 3.1 3 1 0 3 3 3 1 Aluminium activated malate transporter PI-PLC-X PF00388.19 ORX94224.1 - 0.0013 18.3 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SSXT PF05030.12 ORX94224.1 - 0.13 11.9 0.2 4.8 6.9 0.0 2.7 2 1 0 2 2 2 0 SSXT protein (N-terminal region) CENP-T_C PF15511.6 ORX94225.1 - 1.4e-08 34.8 0.1 1.7e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORX94225.1 - 2.2e-05 24.5 0.1 3.1e-05 24.0 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORX94225.1 - 5.2e-05 23.6 0.2 5.7e-05 23.5 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX94225.1 - 7.2e-05 23.1 0.1 0.0001 22.6 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX94225.1 - 0.0001 22.5 0.2 0.00019 21.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX94225.1 - 0.018 15.1 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX94225.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORX94225.1 - 0.15 12.6 0.1 0.29 11.7 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 ORX94226.1 - 3.2e-52 176.4 2.7 3.5e-52 176.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX94226.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX94226.1 - 3e-05 24.1 0.4 4.8e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORX94226.1 - 0.00018 22.1 1.1 0.00021 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORX94226.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX94226.1 - 0.055 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX94226.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Pkinase PF00069.25 ORX94227.1 - 1e-74 251.3 0.0 1.1e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94227.1 - 4e-36 124.6 0.0 5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX94227.1 - 2.6e-05 23.4 0.0 0.00042 19.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX94227.1 - 0.0027 17.1 0.2 0.0052 16.2 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX94227.1 - 0.02 14.2 0.1 0.051 12.9 0.1 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 ORX94227.1 - 0.039 13.9 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family IML1 PF12257.8 ORX94228.1 - 7.2e-119 396.1 1.1 9.3e-119 395.8 0.4 1.6 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 ORX94228.1 - 8.8e-23 80.2 0.3 2e-22 79.1 0.3 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ALMS_motif PF15309.6 ORX94228.1 - 0.25 11.8 1.6 4.7 7.7 0.4 2.6 2 0 0 2 2 2 0 ALMS motif Ribosomal_S27e PF01667.17 ORX94229.1 - 1.1e-29 101.8 4.9 1.5e-29 101.5 4.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORX94229.1 - 0.16 11.5 3.2 0.24 10.9 3.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding SET PF00856.28 ORX94230.1 - 6.1e-11 43.0 0.2 2.5e-09 37.7 0.2 2.3 1 1 0 1 1 1 1 SET domain Peptidase_S9 PF00326.21 ORX94231.1 - 2.5e-57 193.8 0.0 3.6e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORX94231.1 - 1.2e-06 28.4 4.1 0.00031 20.5 2.2 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORX94231.1 - 4e-06 26.6 0.9 0.056 13.0 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 ORX94231.1 - 0.00038 20.3 6.5 0.79 9.7 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 ORX94231.1 - 0.0012 17.6 0.1 0.0027 16.5 0.1 1.6 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 ORX94231.1 - 0.034 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ORX94231.1 - 0.13 11.5 0.1 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Velvet PF11754.8 ORX94232.1 - 2.3e-51 175.1 2.5 1.9e-34 119.8 1.0 2.0 1 1 1 2 2 2 2 Velvet factor 2-Hacid_dh_C PF02826.19 ORX94233.1 - 1.2e-57 194.1 0.0 1.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORX94233.1 - 2.1e-34 118.1 0.0 2.4e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 ORX94233.1 - 0.00035 20.2 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 ORX94233.1 - 0.0007 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ORX94233.1 - 0.0008 19.6 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORX94233.1 - 0.002 18.6 0.0 0.0041 17.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORX94233.1 - 0.004 17.2 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORX94233.1 - 0.0073 16.7 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 ORX94233.1 - 0.03 15.2 0.0 0.049 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Oxidored_FMN PF00724.20 ORX94234.1 - 1.3e-78 264.7 0.0 1.5e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pilin_PilA PF14245.6 ORX94234.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Type IV pilin PilA Acetyltransf_7 PF13508.7 ORX94235.1 - 8.7e-05 22.9 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX94235.1 - 0.00019 21.4 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX94235.1 - 0.0037 17.5 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4202 PF13875.6 ORX94235.1 - 0.097 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) DIL PF01843.19 ORX94236.1 - 4.5e-27 94.4 3.2 1.3e-26 92.9 3.2 1.8 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 ORX94236.1 - 2.7e-15 56.7 0.3 1.4e-10 41.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX94236.1 - 3.5e-11 43.1 0.1 1.3e-05 25.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX94236.1 - 1.6e-08 34.9 0.0 0.00027 21.4 0.1 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORX94236.1 - 2.2e-08 34.2 0.4 0.0064 16.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORX94236.1 - 0.00047 20.4 0.2 7.2 7.5 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat bZIP_1 PF00170.21 ORX94237.1 - 7.2e-10 38.8 11.9 7.5e-10 38.8 9.3 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORX94237.1 - 3.5e-06 27.0 9.5 3.5e-06 27.0 9.5 2.7 2 1 1 3 3 2 1 Basic region leucine zipper DUF1635 PF07795.11 ORX94237.1 - 0.0022 17.9 6.1 0.0054 16.6 6.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) ADIP PF11559.8 ORX94237.1 - 0.014 15.5 13.8 0.032 14.3 13.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding VIT1 PF01988.19 ORX94237.1 - 0.015 15.2 0.4 0.031 14.1 0.4 1.5 1 0 0 1 1 1 0 VIT family Cep57_CLD_2 PF14197.6 ORX94237.1 - 0.016 15.3 7.0 0.033 14.3 7.0 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 ORX94237.1 - 0.076 13.3 0.7 0.076 13.3 0.7 2.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4618 PF15397.6 ORX94237.1 - 0.13 11.7 11.0 0.055 12.9 8.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) FHIPEP PF00771.20 ORX94237.1 - 0.16 10.4 0.7 0.27 9.6 0.7 1.4 1 0 0 1 1 1 0 FHIPEP family Fmp27_WPPW PF10359.9 ORX94237.1 - 0.18 10.7 12.5 0.13 11.1 10.7 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1465 PF07323.12 ORX94237.1 - 0.22 11.3 9.8 0.43 10.4 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) bZIP_Maf PF03131.17 ORX94237.1 - 0.39 11.3 13.1 0.51 10.9 10.6 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor HAUS6_N PF14661.6 ORX94237.1 - 0.61 9.6 9.0 7.3 6.1 8.3 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 ORX94237.1 - 1.3 8.8 7.1 0.43 10.4 3.0 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 ORX94237.1 - 1.9 7.8 6.8 3.4 6.9 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 ORX94237.1 - 3.6 7.6 10.7 7.6 6.6 10.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 ORX94237.1 - 7.1 7.3 12.4 7.3 7.3 9.7 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 ORX94238.1 - 2.9e-73 246.5 0.0 4.2e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94238.1 - 2.1e-36 125.5 0.0 3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 ORX94238.1 - 4.1e-20 72.4 0.1 1.4e-16 61.0 0.0 2.8 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 ORX94238.1 - 1.1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX94238.1 - 0.0016 17.5 1.5 0.005 15.8 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain UBA PF00627.31 ORX94238.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Kdo PF06293.14 ORX94238.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX94238.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UBA_3 PF09288.10 ORX94238.1 - 0.11 12.3 0.1 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.11 ORX94238.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Pkinase PF00069.25 ORX94240.1 - 5.5e-71 239.0 0.0 1.2e-70 238.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94240.1 - 3e-43 148.0 0.0 6.1e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX94240.1 - 0.00062 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX94240.1 - 0.00094 18.1 0.2 0.0039 16.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORX94240.1 - 0.0012 18.0 0.3 0.0021 17.2 0.3 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 ORX94240.1 - 0.0021 17.4 0.1 0.0082 15.5 0.1 2.0 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORX94240.1 - 0.066 12.8 0.4 0.17 11.5 0.4 1.7 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.8 ORX94240.1 - 0.11 12.1 0.5 0.46 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 SH3BP5 PF05276.14 ORX94240.1 - 0.23 11.2 3.4 0.66 9.7 0.1 2.4 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) GATase_4 PF13230.6 ORX94241.1 - 3.5e-19 68.7 0.1 1.3e-18 66.9 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 ORX94241.1 - 6.1e-12 45.9 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain FAD_binding_2 PF00890.24 ORX94242.1 - 1.1e-81 275.1 0.0 1.4e-81 274.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 ORX94242.1 - 2.7e-25 88.3 0.0 4.1e-24 84.5 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ORX94242.1 - 6.4e-12 45.7 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX94242.1 - 6.9e-09 35.4 0.6 9.6e-08 31.6 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX94242.1 - 2.4e-08 33.7 0.5 4.6e-08 32.8 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX94242.1 - 4e-06 26.3 0.9 0.00085 18.7 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX94242.1 - 4.4e-06 26.8 0.5 6.3e-05 23.1 0.4 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX94242.1 - 0.0003 20.0 0.9 0.0046 16.1 0.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORX94242.1 - 0.0006 18.6 4.8 0.0034 16.2 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORX94242.1 - 0.0035 16.7 0.2 0.0072 15.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORX94242.1 - 0.0042 16.4 0.4 0.092 12.0 0.2 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ORX94242.1 - 0.0056 16.0 0.1 0.0095 15.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORX94242.1 - 0.094 13.3 0.8 0.72 10.5 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORX94242.1 - 0.17 12.3 0.1 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding COX7C PF02935.16 ORX94243.1 - 2.5e-19 69.3 0.1 2.6e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Cyclin PF08613.11 ORX94245.1 - 1.1e-05 25.8 0.0 1.5e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX94245.1 - 0.0029 17.4 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain GCD14 PF08704.10 ORX94246.1 - 2.1e-16 60.3 0.0 5.3e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 ORX94246.1 - 4.1e-05 23.4 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX94246.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ORX94246.1 - 0.00084 20.0 0.0 0.0015 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 ORX94246.1 - 0.0011 18.8 0.1 0.0028 17.5 0.1 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_32 PF13679.6 ORX94246.1 - 0.003 17.6 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ORX94246.1 - 0.0069 17.4 0.0 0.012 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX94246.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.12 ORX94246.1 - 0.029 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Cyclin PF08613.11 ORX94247.1 - 2e-15 57.5 0.0 2.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX94247.1 - 3.9e-06 26.6 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain KASH PF10541.9 ORX94247.1 - 0.088 13.1 0.3 0.23 11.8 0.3 1.8 1 1 0 1 1 1 0 Nuclear envelope localisation domain Alk_phosphatase PF00245.20 ORX94248.1 - 9e-98 327.9 1.5 2.1e-57 195.0 0.1 2.1 1 1 1 2 2 2 2 Alkaline phosphatase DUF1729 PF08354.10 ORX94248.1 - 0.0022 16.9 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Metalloenzyme PF01676.18 ORX94248.1 - 0.029 13.7 0.1 0.083 12.2 0.1 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily MFS_1 PF07690.16 ORX94249.1 - 7.2e-38 130.4 31.9 1e-37 129.9 31.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M17 PF00883.21 ORX94250.1 - 1.5e-126 421.9 0.1 2e-126 421.5 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ORX94250.1 - 1.6e-24 86.1 3.9 3.5e-24 85.1 3.9 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PPR_2 PF13041.6 ORX94251.1 - 4.6e-63 209.2 13.7 2.4e-11 43.6 0.0 11.9 4 2 8 12 12 12 9 PPR repeat family PPR_3 PF13812.6 ORX94251.1 - 5.7e-53 176.9 12.6 7.9e-12 45.1 0.0 9.6 5 2 7 12 12 12 10 Pentatricopeptide repeat domain PPR PF01535.20 ORX94251.1 - 5.2e-33 111.0 16.0 6.7e-05 22.9 0.0 14.3 16 0 0 16 16 16 5 PPR repeat PPR_1 PF12854.7 ORX94251.1 - 2e-28 97.8 0.8 1.1e-05 25.1 0.0 10.9 12 0 0 12 12 12 6 PPR repeat PPR_long PF17177.4 ORX94251.1 - 3e-25 88.8 4.8 1.4e-08 34.4 0.1 4.5 1 1 4 5 5 5 4 Pentacotripeptide-repeat region of PRORP SNRNP27 PF08648.12 ORX94251.1 - 4.4e-13 49.1 0.4 1.1e-12 47.8 0.4 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RPM2 PF08579.11 ORX94251.1 - 1.9e-06 28.3 12.7 0.081 13.3 0.9 6.1 3 2 2 5 5 5 3 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORX94251.1 - 4.4e-05 23.9 2.0 7.7 7.6 0.0 7.1 7 2 2 9 9 6 1 Tetratricopeptide repeat AEP1 PF17049.5 ORX94251.1 - 0.0032 16.6 2.6 3 6.8 0.2 3.8 1 1 1 3 3 3 1 ATPase expression protein 1 RabGAP-TBC PF00566.18 ORX94251.1 - 0.0059 16.3 0.5 1.3 8.7 0.3 3.5 2 2 2 4 4 4 2 Rab-GTPase-TBC domain TPR_19 PF14559.6 ORX94251.1 - 0.0065 16.9 2.6 5.5 7.6 0.2 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX94251.1 - 0.0068 15.3 0.5 1.5 7.6 0.0 2.8 3 0 0 3 3 3 1 Mitochondrial 28S ribosomal protein S27 Prp18 PF02840.15 ORX94251.1 - 0.01 15.9 1.4 0.48 10.5 0.2 3.3 3 0 0 3 3 3 0 Prp18 domain Exog_C PF18026.1 ORX94251.1 - 0.018 15.1 0.0 21 5.2 0.0 4.7 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain TPR_7 PF13176.6 ORX94251.1 - 0.085 12.9 0.3 66 3.9 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX94251.1 - 6.4 7.2 9.2 38 4.7 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 ORX94252.1 - 8.3e-32 111.0 0.0 1e-31 110.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORX94252.1 - 5e-12 45.9 0.1 1.1e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX94252.1 - 1.1e-07 31.8 0.0 2.3e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORX94252.1 - 0.00011 21.5 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 ORX94252.1 - 0.0029 16.5 0.2 0.0084 15.0 0.2 1.7 2 0 0 2 2 2 1 Tryptophan halogenase MCRA PF06100.11 ORX94252.1 - 0.0033 16.3 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 ORX94252.1 - 0.007 15.6 0.0 0.15 11.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX94252.1 - 0.015 15.3 0.1 0.094 12.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 ORX94252.1 - 0.033 13.3 0.1 0.47 9.5 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORX94252.1 - 0.051 12.9 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AMP-binding PF00501.28 ORX94270.1 - 0 1850.2 0.0 6.4e-95 318.2 0.0 6.5 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 ORX94270.1 - 0 1520.4 37.3 9.6e-54 182.8 0.2 11.9 11 1 0 11 11 11 10 Condensation domain PP-binding PF00550.25 ORX94270.1 - 2.9e-84 277.4 2.3 1.2e-12 48.0 0.1 7.3 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX94270.1 - 3.4e-47 159.3 0.1 2.8e-08 34.6 0.0 6.8 6 0 0 6 6 6 6 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 ORX94270.1 - 6.1e-22 78.9 0.0 2.3e-21 77.0 0.0 2.1 1 0 0 1 1 1 1 Thioesterase domain Ins134_P3_kin PF05770.11 ORX94270.1 - 0.0083 15.7 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain DUF5122 PF17164.4 ORX94270.1 - 0.22 11.8 4.6 1.7e+02 2.6 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller MFS_1 PF07690.16 ORX94271.1 - 1.3e-46 159.1 47.4 7e-46 156.8 42.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 ORX94274.1 - 1.1e-68 225.4 14.3 1.6e-11 44.5 0.3 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX94274.1 - 1.2e-19 70.3 1.3 2.6e-07 30.8 0.0 5.1 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX94274.1 - 1.4e-11 43.8 3.2 0.38 9.3 0.1 6.1 3 1 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORX94274.1 - 1.3e-06 27.5 2.0 1.2 7.8 0.0 4.7 2 1 3 5 5 5 3 Nup133 N terminal like LisH PF08513.11 ORX94274.1 - 0.00014 21.7 0.1 0.00034 20.4 0.1 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 ORX94274.1 - 0.0004 20.3 0.5 0.13 12.1 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Pox_A_type_inc PF04508.12 ORX94274.1 - 0.002 17.9 0.3 0.0044 16.8 0.3 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Ge1_WD40 PF16529.5 ORX94274.1 - 0.0025 16.8 6.5 0.77 8.7 0.2 3.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Lipid_DES PF08557.10 ORX94274.1 - 0.049 13.1 0.0 16 5.1 0.0 3.0 3 0 0 3 3 3 0 Sphingolipid Delta4-desaturase (DES) PALB2_WD40 PF16756.5 ORX94274.1 - 0.065 12.1 0.8 2.3 7.0 0.0 3.0 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain NBP1 PF08537.10 ORX94274.1 - 0.17 11.3 0.6 0.23 10.8 0.6 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 ComS PF17584.2 ORX94274.1 - 0.17 11.4 0.4 2.9 7.5 0.1 2.9 3 0 0 3 3 3 0 Bacillus competence protein S CLASP_N PF12348.8 ORX94275.1 - 1.9e-28 99.6 0.2 3.2e-07 30.1 0.0 6.6 6 2 0 6 6 6 3 CLASP N terminal HEAT PF02985.22 ORX94275.1 - 3.2e-18 64.2 10.1 0.0033 17.5 0.0 10.0 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 ORX94275.1 - 2.1e-12 47.3 3.7 0.1 13.0 0.0 8.9 7 1 2 9 9 9 2 HEAT repeats Cnd1 PF12717.7 ORX94275.1 - 2e-10 41.0 9.5 0.051 13.6 0.0 8.6 7 2 0 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORX94275.1 - 3.8e-10 40.2 0.1 0.71 10.5 0.0 7.0 7 0 0 7 7 6 2 Vacuolar 14 Fab1-binding region TAN PF11640.8 ORX94275.1 - 3.1e-08 33.9 6.1 1.2 9.2 0.0 7.2 7 0 0 7 7 7 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 ORX94275.1 - 2.4e-06 27.9 5.9 2.8 8.6 0.0 7.5 7 1 1 8 8 8 3 HEAT-like repeat RTP1_C1 PF10363.9 ORX94275.1 - 2.2e-05 24.6 0.3 8.1 6.7 0.0 6.4 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 ORX94275.1 - 0.0082 16.4 0.1 0.26 11.6 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 ORX94275.1 - 0.015 13.9 7.5 3 6.3 0.1 5.4 5 1 0 6 6 6 0 Adaptin N terminal region DCB PF16213.5 ORX94275.1 - 0.23 11.1 2.2 1.5 8.4 0.0 3.2 4 0 0 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 MFS_1 PF07690.16 ORX94276.1 - 3.6e-37 128.1 74.3 1.5e-35 122.8 47.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORX94276.1 - 1e-05 25.0 19.0 1e-05 25.0 19.0 2.1 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORX94276.1 - 2.1e-05 23.6 27.5 0.0027 16.6 23.1 2.2 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 ORX94276.1 - 2.2e-05 23.5 39.0 7.3e-05 21.8 5.5 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 ORX94276.1 - 0.0046 15.6 6.8 0.0046 15.6 6.8 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein DnaJ PF00226.31 ORX94277.1 - 1e-09 38.4 2.0 2e-09 37.4 0.2 2.5 3 0 0 3 3 3 1 DnaJ domain Csm1 PF12539.8 ORX94278.1 - 3.4e-15 56.4 0.0 6.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 ORX94278.1 - 2.4e-06 27.8 4.5 2.4e-06 27.8 4.5 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF5094) End3 PF12761.7 ORX94278.1 - 0.0081 16.4 9.6 0.0081 16.4 9.6 1.6 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 FAM184 PF15665.5 ORX94278.1 - 0.0096 15.7 9.9 0.015 15.1 9.9 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B FlxA PF14282.6 ORX94278.1 - 0.019 14.9 14.2 0.051 13.6 14.2 1.8 1 0 0 1 1 1 0 FlxA-like protein Bap31_Bap29_C PF18035.1 ORX94278.1 - 0.057 13.4 12.3 0.4 10.7 6.2 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FRB_dom PF08771.11 ORX94278.1 - 0.069 13.6 2.5 0.16 12.4 2.5 1.6 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain DUF5344 PF17279.2 ORX94278.1 - 0.13 12.9 0.1 0.13 12.9 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) V_ATPase_I PF01496.19 ORX94278.1 - 0.13 10.2 4.3 0.21 9.4 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 ORX94278.1 - 0.25 11.4 15.8 1.8 8.6 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NRBF2 PF08961.10 ORX94278.1 - 0.32 10.6 10.1 0.013 15.1 3.2 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4618 PF15397.6 ORX94278.1 - 0.33 10.3 11.0 0.52 9.7 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Spc24 PF08286.11 ORX94278.1 - 0.5 10.6 12.2 0.31 11.3 7.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 ORX94278.1 - 0.5 9.7 15.9 0.011 15.1 9.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 ORX94278.1 - 0.51 10.9 11.0 1.5 9.4 11.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 FemAB PF02388.16 ORX94278.1 - 0.59 8.9 10.1 0.94 8.3 10.1 1.2 1 0 0 1 1 1 0 FemAB family Uds1 PF15456.6 ORX94278.1 - 0.85 9.8 14.8 0.018 15.2 7.0 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF4446 PF14584.6 ORX94278.1 - 1.8 8.5 5.7 0.86 9.6 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 ORX94278.1 - 4.8 6.3 6.8 7 5.8 6.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein HR1 PF02185.16 ORX94278.1 - 5.6 7.1 15.4 0.27 11.4 0.2 3.1 2 1 1 3 3 3 0 Hr1 repeat ABC_tran_CTD PF16326.5 ORX94278.1 - 6.7 7.0 13.4 12 6.3 0.2 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Malate_synthase PF01274.22 ORX94279.1 - 2.5e-224 745.4 0.0 2.8e-224 745.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF4485 PF14846.6 ORX94279.1 - 0.096 12.7 1.7 0.39 10.8 1.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) HTH_Tnp_1_2 PF13022.6 ORX94279.1 - 0.14 12.3 1.3 0.35 11.0 1.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase WD40 PF00400.32 ORX94280.1 - 1.1e-37 127.4 20.0 5.3e-09 36.6 0.5 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX94280.1 - 2.2e-18 66.3 7.0 0.00027 21.2 0.1 5.9 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX94280.1 - 3.5e-08 33.6 4.5 0.00057 19.8 0.3 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX94280.1 - 0.0048 15.9 0.5 0.12 11.3 0.2 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 ORX94280.1 - 0.21 9.6 2.1 0.86 7.5 0.1 2.5 1 1 0 2 2 2 0 IKI3 family WD40_like PF17005.5 ORX94280.1 - 0.22 10.8 0.0 5.2 6.3 0.0 2.7 1 1 1 3 3 3 0 WD40-like domain Malate_synthase PF01274.22 ORX94281.1 - 3.5e-156 520.6 0.1 3.9e-156 520.4 0.1 1.0 1 0 0 1 1 1 1 Malate synthase HTH_Tnp_1_2 PF13022.6 ORX94281.1 - 0.066 13.4 0.9 0.15 12.2 0.9 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase SurA_N_2 PF13623.6 ORX94281.1 - 0.12 12.3 0.5 0.27 11.1 0.3 1.7 2 0 0 2 2 2 0 SurA N-terminal domain DUF4485 PF14846.6 ORX94281.1 - 1.7 8.7 6.9 0.21 11.6 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) RasGAP PF00616.19 ORX94302.1 - 4.1e-60 203.1 1.5 4.9e-60 202.8 0.0 2.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORX94302.1 - 7.1e-32 110.4 2.3 4.3e-31 107.9 0.1 2.6 2 0 0 2 2 2 1 RasGAP C-terminus YabA PF06156.13 ORX94302.1 - 0.5 11.0 12.3 2.3 8.9 0.7 4.0 5 0 0 5 5 5 0 Initiation control protein YabA CAP_N PF01213.19 ORX94304.1 - 2.6 7.4 4.1 3 7.2 4.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ORX94304.1 - 6.7 6.8 6.5 10 6.2 6.5 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C2H2_4 PF13894.6 ORX94305.1 - 1.9e-07 31.3 9.7 0.0024 18.5 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX94305.1 - 8.9e-07 29.0 9.4 0.0011 19.3 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX94305.1 - 9.5e-06 25.8 14.4 1.4e-05 25.3 1.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX94305.1 - 0.00039 20.7 5.4 0.17 12.3 2.1 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX94305.1 - 0.014 15.7 5.7 0.32 11.3 2.7 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Acyltransf_C PF16076.5 ORX94305.1 - 0.029 14.4 0.2 0.32 11.1 0.1 1.9 1 1 1 2 2 2 0 Acyltransferase C-terminus DUF4729 PF15866.5 ORX94305.1 - 0.063 12.6 0.2 0.063 12.6 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) zf-LYAR PF08790.11 ORX94305.1 - 0.22 11.5 4.0 0.23 11.4 1.2 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 ORX94306.1 - 1.3e-10 41.1 13.5 7.8e-05 22.9 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX94306.1 - 6.8e-09 35.8 10.6 0.00054 20.6 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX94306.1 - 2.5e-07 30.9 1.6 0.012 16.0 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORX94306.1 - 7.8e-07 29.2 8.4 1.5e-06 28.4 3.7 3.1 4 0 0 4 4 3 2 Zinc-finger double domain zf-Di19 PF05605.12 ORX94306.1 - 0.00057 20.1 3.5 0.098 13.0 1.0 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORX94306.1 - 0.00059 20.1 8.5 0.095 13.0 2.2 2.7 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 ORX94306.1 - 0.02 15.6 1.0 0.043 14.5 0.9 1.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF1091 PF06477.13 ORX94306.1 - 0.023 15.2 0.7 0.037 14.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DUF4729 PF15866.5 ORX94306.1 - 0.046 13.0 5.5 0.13 11.6 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) Acyltransf_C PF16076.5 ORX94306.1 - 0.054 13.6 0.3 0.18 11.9 0.3 1.9 1 1 0 1 1 1 0 Acyltransferase C-terminus zf-C2H2_6 PF13912.6 ORX94306.1 - 0.21 11.6 0.6 0.21 11.6 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORX94306.1 - 0.78 10.1 6.1 2.8 8.4 0.5 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 ORX94306.1 - 1.1 9.2 5.0 10 6.1 0.5 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 ORX94306.1 - 1.2 9.8 4.2 2.1 9.0 0.5 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-BED PF02892.15 ORX94306.1 - 2.7 8.1 10.8 2.8 8.0 1.4 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 ORX94307.1 - 5.8e-10 39.1 14.8 6e-06 26.4 2.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX94307.1 - 1.3e-08 34.9 16.7 7e-06 26.2 7.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX94307.1 - 8.4e-07 29.3 12.8 0.00031 21.3 1.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX94307.1 - 1.4e-05 24.9 1.2 1.4e-05 24.9 1.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX94307.1 - 0.0094 16.2 0.6 0.0094 16.2 0.6 2.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX94307.1 - 0.019 15.3 5.3 0.03 14.7 0.3 2.5 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORX94307.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PHP PF02811.19 ORX94308.1 - 0.0002 21.7 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 PHP domain Arteri_Gl PF00951.18 ORX94308.1 - 0.13 12.1 2.0 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein CP2 PF04516.15 ORX94309.1 - 1.8e-54 184.5 0.4 3.7e-54 183.5 0.1 1.6 2 0 0 2 2 2 1 CP2 transcription factor FAS_meander PF17951.1 ORX94309.1 - 0.09 12.6 0.9 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Fatty acid synthase meander beta sheet domain UQ_con PF00179.26 ORX94311.1 - 1.2e-15 57.4 0.9 1.2e-15 57.4 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX94311.1 - 0.13 12.5 0.7 0.38 11.0 0.7 1.9 1 1 0 1 1 1 0 RWD domain Tubulin PF00091.25 ORX94312.1 - 9.1e-68 228.3 0.0 1.3e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX94312.1 - 7.5e-51 171.5 0.0 1.2e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORX94312.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Glyco_hydro_47 PF01532.20 ORX94313.1 - 2.3e-177 590.5 0.0 2.7e-177 590.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ETF_QO PF05187.13 ORX94314.1 - 5.8e-47 158.1 0.1 1e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 ORX94314.1 - 1.2e-08 35.0 0.0 3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ORX94314.1 - 1e-07 31.4 0.0 6.2e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORX94314.1 - 3.5e-07 29.7 0.8 0.00011 21.4 1.8 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORX94314.1 - 4.5e-07 30.0 0.0 3.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORX94314.1 - 2.5e-06 26.9 0.1 3.3e-05 23.3 0.2 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX94314.1 - 1.3e-05 25.6 0.8 0.031 14.8 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX94314.1 - 3.4e-05 23.9 0.1 9.5e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORX94314.1 - 0.00021 20.3 0.1 0.011 14.6 0.5 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 ORX94314.1 - 0.00037 20.0 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX94314.1 - 0.00045 19.0 0.7 0.00073 18.4 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Fer4_7 PF12838.7 ORX94314.1 - 0.00079 20.0 1.1 0.0019 18.8 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 ORX94314.1 - 0.00088 18.6 0.1 0.0014 17.9 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORX94314.1 - 0.0027 16.8 0.2 0.0042 16.2 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORX94314.1 - 0.0052 16.1 0.4 0.0084 15.4 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DnaJ_C PF01556.18 ORX94314.1 - 0.05 13.7 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain K_oxygenase PF13434.6 ORX94314.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_10 PF13237.6 ORX94314.1 - 0.17 12.1 0.7 0.35 11.0 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain PPR_2 PF13041.6 ORX94315.1 - 5.8e-65 215.3 17.4 4.6e-13 49.1 0.0 9.7 3 2 7 10 10 10 9 PPR repeat family PPR PF01535.20 ORX94315.1 - 2e-46 153.0 18.8 6.8e-06 26.0 0.0 11.5 11 1 0 11 11 11 9 PPR repeat PPR_3 PF13812.6 ORX94315.1 - 1.2e-45 153.5 1.9 9.2e-12 44.9 0.2 7.3 5 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX94315.1 - 6.5e-44 147.3 12.6 1.3e-06 28.0 0.0 10.1 11 0 0 11 11 11 7 PPR repeat PPR_long PF17177.4 ORX94315.1 - 7.3e-27 94.1 2.0 3.3e-11 43.0 0.1 5.2 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX94315.1 - 7.2e-06 26.4 0.1 15 6.7 0.0 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat ATP13 PF12921.7 ORX94315.1 - 0.0001 22.2 3.7 27 4.7 0.1 6.2 3 2 2 6 6 6 0 Mitochondrial ATPase expression BTAD PF03704.17 ORX94315.1 - 0.26 11.7 1.8 16 5.9 0.0 3.4 3 1 1 4 4 4 0 Bacterial transcriptional activator domain HD_4 PF13328.6 ORX94316.1 - 7.4e-20 71.3 3.3 1.5e-19 70.3 3.3 1.5 1 1 0 1 1 1 1 HD domain HD PF01966.22 ORX94316.1 - 8e-05 22.9 0.9 0.00019 21.6 0.9 1.6 1 1 0 1 1 1 1 HD domain FAM184 PF15665.5 ORX94316.1 - 0.0079 16.0 0.9 0.011 15.6 0.9 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B KxDL PF10241.9 ORX94316.1 - 0.041 14.2 0.4 0.097 13.0 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein HLH PF00010.26 ORX94316.1 - 0.071 13.1 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain StbA PF06406.11 ORX94316.1 - 0.088 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 StbA protein DUF92 PF01940.16 ORX94317.1 - 5.4e-76 255.1 5.7 6.3e-76 254.9 5.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Peptidase_A8 PF01252.18 ORX94317.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.1 3 0 0 3 3 3 0 Signal peptidase (SPase) II DUF1430 PF07242.11 ORX94317.1 - 2.1 8.6 5.4 1.7 9.0 0.1 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1430) Cofilin_ADF PF00241.20 ORX94318.1 - 1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 ORX94318.1 - 5.4e-08 33.3 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORX94318.1 - 0.00088 19.7 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3306 PF11748.8 ORX94318.1 - 1.6 9.6 8.3 0.71 10.8 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) ASF1_hist_chap PF04729.13 ORX94319.1 - 1.2e-72 242.9 0.3 1.4e-72 242.7 0.3 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.13 ORX94319.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Spermine_synth PF01564.17 ORX94320.1 - 8.8e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 ORX94320.1 - 0.00011 22.1 0.1 0.00025 20.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX94320.1 - 0.00051 20.7 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX94320.1 - 0.00054 20.5 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX94320.1 - 0.092 13.5 0.0 0.38 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.11 ORX94320.1 - 0.2 11.5 0.0 0.58 10.0 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase ABC_membrane PF00664.23 ORX94321.1 - 6.6e-55 186.7 26.6 8.4e-34 117.5 13.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX94321.1 - 1.1e-50 171.7 0.0 9.4e-27 94.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORX94321.1 - 1.5e-10 40.9 0.1 0.16 11.4 0.0 4.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX94321.1 - 2.9e-07 31.0 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 ORX94321.1 - 1.1e-05 24.6 0.0 0.046 12.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 ORX94321.1 - 2.1e-05 24.8 0.6 0.061 13.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORX94321.1 - 5e-05 23.2 2.7 0.5 10.1 0.1 4.0 4 1 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORX94321.1 - 6.1e-05 23.1 0.4 0.022 14.8 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ORX94321.1 - 6.7e-05 23.5 0.5 1.8 9.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 ORX94321.1 - 7.2e-05 23.0 1.6 0.031 14.4 0.0 3.6 2 1 1 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 ORX94321.1 - 0.00012 22.0 0.1 0.87 9.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORX94321.1 - 0.00021 21.0 0.1 0.2 11.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ORX94321.1 - 0.00022 21.0 0.3 1.2 8.9 0.0 3.4 4 0 0 4 4 3 2 IstB-like ATP binding protein Dynamin_N PF00350.23 ORX94321.1 - 0.00095 19.3 0.2 1.1 9.2 0.1 2.7 2 0 0 2 2 2 2 Dynamin family AAA_PrkA PF08298.11 ORX94321.1 - 0.0014 17.6 0.2 1 8.2 0.0 2.5 3 0 0 3 3 3 2 PrkA AAA domain AAA_7 PF12775.7 ORX94321.1 - 0.0035 16.9 0.1 0.79 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 ORX94321.1 - 0.0051 17.2 0.1 0.055 13.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ORX94321.1 - 0.0054 16.6 0.1 0.39 10.5 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TsaE PF02367.17 ORX94321.1 - 0.0063 16.5 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORX94321.1 - 0.0093 16.5 0.4 4.4 7.9 0.1 3.3 2 1 1 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 ORX94321.1 - 0.01 14.8 0.1 0.19 10.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 ORX94321.1 - 0.01 15.5 0.1 6.6 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 ORX94321.1 - 0.011 15.5 0.1 1.3 8.7 0.1 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.19 ORX94321.1 - 0.015 14.9 0.4 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORX94321.1 - 0.024 13.8 0.2 2.4 7.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ResIII PF04851.15 ORX94321.1 - 0.032 14.2 0.0 5.6 6.9 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MeaB PF03308.16 ORX94321.1 - 0.034 13.1 0.0 0.3 10.0 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ORX94321.1 - 0.059 13.3 0.9 6.4 6.7 0.0 3.0 3 0 0 3 3 2 0 NACHT domain Zeta_toxin PF06414.12 ORX94321.1 - 0.077 12.3 0.1 5.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 ORX94321.1 - 0.08 13.2 0.3 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 ORX94321.1 - 0.11 12.3 0.3 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 ORX94321.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 ORX94321.1 - 0.18 11.7 2.0 38 4.1 0.0 4.0 4 0 0 4 4 4 0 NTPase AAA_33 PF13671.6 ORX94321.1 - 0.28 11.3 0.7 4.9 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Glyco_hydro_46 PF01374.18 ORX94322.1 - 2.6e-45 154.6 0.0 3.3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Orthopox_B11R PF07033.11 ORX94333.1 - 0.14 11.9 0.6 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Orthopoxvirus B11R protein Pkinase PF00069.25 ORX94335.1 - 2.1e-73 246.9 0.4 3.4e-73 246.3 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94335.1 - 9.5e-43 146.3 0.5 3.4e-42 144.5 0.5 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORX94335.1 - 2.1e-16 59.4 0.0 3.9e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 ORX94335.1 - 3.8e-07 29.4 0.2 8.1e-07 28.3 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX94335.1 - 7.2e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORX94335.1 - 0.00014 21.3 0.5 0.00026 20.4 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX94335.1 - 0.00036 20.2 0.5 0.00036 20.2 0.5 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 ORX94335.1 - 0.0015 18.5 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 ORX94335.1 - 0.027 14.0 0.3 0.067 12.7 0.3 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Cyclin PF08613.11 ORX94336.1 - 0.00011 22.7 0.4 0.089 13.2 0.5 2.7 2 1 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 ORX94336.1 - 0.0035 17.1 0.0 0.016 15.0 0.0 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Fer4_24 PF18109.1 ORX94337.1 - 0.097 13.0 0.2 0.32 11.3 0.2 1.9 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain RNA_pol_Rpb5_C PF01191.19 ORX94337.1 - 0.1 12.5 1.5 0.73 9.7 0.4 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain 4HBT PF03061.22 ORX94338.1 - 1e-08 35.4 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ORX94338.1 - 7.7e-06 26.4 0.0 1e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORX94338.1 - 0.0003 20.2 0.0 0.0026 17.1 0.1 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase DDE_Tnp_1_7 PF13843.6 ORX94339.1 - 7.6e-06 25.5 0.2 0.044 13.1 0.1 2.2 1 1 1 2 2 2 2 Transposase IS4 DUF4111 PF13427.6 ORX94340.1 - 0.16 12.2 0.1 0.47 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) XG_FTase PF03254.13 ORX94340.1 - 0.17 10.4 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Pkr1 PF08636.10 ORX94343.1 - 2.5e-20 72.4 1.5 2.8e-20 72.2 1.5 1.0 1 0 0 1 1 1 1 ER protein Pkr1 MscL PF01741.18 ORX94343.1 - 0.011 16.0 0.5 0.013 15.8 0.5 1.1 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF443 PF04276.12 ORX94343.1 - 0.035 13.9 2.1 0.041 13.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) SLATT_4 PF18186.1 ORX94343.1 - 0.057 13.1 1.4 0.073 12.7 1.4 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Qua1 PF16274.5 ORX94343.1 - 0.092 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Qua1 domain Myco_arth_vir_N PF09610.10 ORX94343.1 - 1.3 9.2 4.4 1.2 9.2 1.3 2.3 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Pectate_lyase_3 PF12708.7 ORX94344.1 - 4.4e-05 23.4 0.6 0.00034 20.5 0.0 2.2 2 0 0 2 2 2 1 Pectate lyase superfamily protein DUF4955 PF16315.5 ORX94344.1 - 0.0018 18.5 1.8 0.0066 16.6 1.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4955) Ribosomal_L7Ae PF01248.26 ORX94345.1 - 3.3e-24 84.4 0.0 3.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Polysacc_deac_1 PF01522.21 ORX94347.1 - 1.7e-29 102.2 0.0 2.9e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase CASP_C PF08172.12 ORX94347.1 - 6.4 6.0 6.3 10 5.4 6.3 1.3 1 0 0 1 1 1 0 CASP C terminal Peptidase_S15 PF02129.18 ORX94348.1 - 0.04 13.5 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_hydro_31 PF01055.26 ORX94349.1 - 1.2e-155 519.0 2.0 1.6e-155 518.6 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORX94349.1 - 4.3e-32 110.7 0.0 2.3e-31 108.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORX94349.1 - 1.8e-09 37.8 0.0 6.2e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like eRF1_1 PF03463.15 ORX94350.1 - 0.2 11.7 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Fz PF01392.22 ORX94351.1 - 0.0007 20.2 2.2 0.0012 19.5 2.2 1.4 1 0 0 1 1 1 1 Fz domain Trypsin PF00089.26 ORX94352.1 - 1.1e-38 133.3 0.0 1.3e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX94352.1 - 3e-06 28.2 0.1 5.2e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Bax1-I PF01027.20 ORX94353.1 - 3.2e-50 170.9 31.5 3.7e-50 170.6 31.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_P21 PF05313.12 ORX94353.1 - 0.1 12.1 5.9 0.19 11.3 5.9 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Vma12 PF11712.8 ORX94353.1 - 5.3 7.1 9.8 3.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3234 PF11572.8 ORX94354.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) Mon1 PF03164.14 ORX94355.1 - 1.9e-145 485.0 1.1 2.3e-145 484.7 1.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF3922 PF13059.6 ORX94355.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) GFD1 PF17331.2 ORX94355.1 - 0.18 12.1 1.9 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 GFD1 mRNA transport factor Ndc80_HEC PF03801.13 ORX94356.1 - 3.8e-50 169.5 0.2 1e-49 168.0 0.2 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 ORX94356.1 - 9.9e-11 41.6 3.3 9.9e-11 41.6 3.3 5.7 5 2 2 7 7 7 1 Domain of unknown function (DUF5595) DHR10 PF18595.1 ORX94356.1 - 0.0058 16.7 16.2 0.0058 16.7 16.2 4.1 3 2 1 4 4 4 2 Designed helical repeat protein 10 domain NLRC4_HD PF17889.1 ORX94356.1 - 0.41 11.0 0.1 0.41 11.0 0.1 3.6 4 2 0 4 4 4 0 NLRC4 helical domain Golgin_A5 PF09787.9 ORX94356.1 - 0.56 9.6 47.0 0.011 15.3 16.1 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 ABC_tran_CTD PF16326.5 ORX94356.1 - 1.3 9.3 39.7 0.35 11.1 8.0 5.1 2 2 2 4 4 4 0 ABC transporter C-terminal domain DUF4407 PF14362.6 ORX94356.1 - 2 7.7 32.7 0.99 8.7 6.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) ERM PF00769.19 ORX94356.1 - 4 7.2 52.4 3.1 7.6 26.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family MRFAP1 PF15155.6 ORX94356.1 - 4.3 7.9 13.2 1.3 9.6 1.7 3.4 2 1 1 3 3 3 0 MORF4 family-associated protein1 Spc7 PF08317.11 ORX94356.1 - 5 5.9 61.4 0.46 9.3 22.5 4.1 2 2 2 4 4 4 0 Spc7 kinetochore protein DUF883 PF05957.13 ORX94356.1 - 7.6 7.2 20.1 1.8 9.2 0.3 5.0 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb2_6 PF00562.28 ORX94369.1 - 0.027 13.5 0.2 0.031 13.4 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Ldh_1_N PF00056.23 ORX94370.1 - 8.7e-49 165.2 0.2 2.4e-48 163.8 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX94370.1 - 8.8e-48 162.4 0.1 1.3e-47 161.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 ORX94370.1 - 0.00087 18.9 0.8 0.096 12.2 0.1 2.9 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 ORX94370.1 - 0.0082 15.2 0.0 0.019 14.0 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 ORX94370.1 - 0.046 13.0 0.1 0.42 9.9 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 ORX94370.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 ORX94370.1 - 0.11 13.0 0.1 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ORX94371.1 - 5.7e-49 165.8 0.2 1.4e-48 164.6 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX94371.1 - 6e-35 120.6 0.0 9.3e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 ORX94371.1 - 0.00043 19.9 0.9 0.066 12.8 0.2 2.9 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 ORX94371.1 - 0.0049 15.9 0.0 0.013 14.6 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 ORX94371.1 - 0.032 13.5 0.4 0.28 10.5 0.2 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 ORX94371.1 - 0.06 13.8 0.1 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX94371.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NCD1 PF04904.13 ORX94372.1 - 0.00017 21.5 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) SAM_1 PF00536.30 ORX94372.1 - 0.002 18.5 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD2 PF04905.13 ORX94372.1 - 0.0029 17.6 0.8 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 NAB conserved region 2 (NCD2) SAPS PF04499.15 ORX94372.1 - 0.13 11.0 5.0 0.17 10.6 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UCH PF00443.29 ORX94374.1 - 4.2e-50 170.6 0.2 6.3e-50 170.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORX94374.1 - 6.5e-11 42.4 7.1 6.5e-11 42.4 7.1 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORX94374.1 - 6.5e-09 35.8 10.6 6.9e-08 32.4 2.0 3.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PGP_phosphatase PF09419.10 ORX94375.1 - 2.1e-41 141.4 0.0 2.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 ORX94375.1 - 2e-05 24.6 0.0 4.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Muted PF14942.6 ORX94376.1 - 0.026 14.9 4.4 0.028 14.7 4.4 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Laminin_II PF06009.12 ORX94376.1 - 0.042 13.9 4.1 0.052 13.6 4.1 1.3 1 1 0 1 1 1 0 Laminin Domain II UPF0184 PF03670.13 ORX94376.1 - 0.044 14.2 4.3 0.046 14.1 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Hemagglutinin PF00509.18 ORX94376.1 - 0.092 11.1 1.1 0.088 11.2 1.1 1.0 1 0 0 1 1 1 0 Haemagglutinin DUF724 PF05266.14 ORX94376.1 - 0.26 11.1 4.6 0.28 11.0 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 ORX94376.1 - 2.6 8.3 7.8 1.4 9.2 4.1 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 XhlA PF10779.9 ORX94376.1 - 4.2 7.6 6.4 1.2 9.4 2.1 2.0 1 1 0 2 2 2 0 Haemolysin XhlA Mito_carr PF00153.27 ORX94377.1 - 1.2e-65 217.4 8.0 2.6e-22 78.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TF_Otx PF03529.13 ORX94377.1 - 0.088 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Otx1 transcription factor NIF PF03031.18 ORX94378.1 - 3.9e-52 176.2 0.2 4.8e-52 175.9 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORX94378.1 - 0.14 12.5 0.5 0.68 10.3 0.1 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Glycoprotein_G PF00802.19 ORX94379.1 - 4.1 6.7 11.3 4.1 6.7 11.3 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Aa_trans PF01490.18 ORX94380.1 - 1.8e-63 214.7 36.5 2.1e-63 214.5 36.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORX94380.1 - 1.2e-06 27.6 28.9 1.3e-06 27.5 27.0 2.0 1 1 1 2 2 2 1 Spore germination protein BacteriocIIc_cy PF12173.8 ORX94380.1 - 5.6 7.3 16.7 22 5.4 0.3 4.8 5 0 0 5 5 5 0 Bacteriocin class IIc cyclic gassericin A-like CLZ PF16526.5 ORX94381.1 - 0.21 11.9 3.0 3.8 7.9 0.0 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tetraspanin PF00335.20 ORX94382.1 - 2.2e-12 47.2 0.4 2.6e-12 46.9 0.4 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2244 PF10003.9 ORX94382.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) ABC2_membrane_3 PF12698.7 ORX94383.1 - 3.2e-22 79.1 6.8 1.7e-20 73.5 6.8 2.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 ORX94383.1 - 3.2e-22 79.5 0.0 5.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX94383.1 - 1.3e-10 41.6 0.1 2.6e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORX94383.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ORX94383.1 - 0.014 15.2 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 ORX94383.1 - 0.097 12.1 0.0 8.9 5.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX94383.1 - 0.1 12.4 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsX PF02687.21 ORX94383.1 - 0.62 10.6 11.2 1.8 9.1 9.3 2.6 2 0 0 2 2 2 0 FtsX-like permease family Yippee-Mis18 PF03226.14 ORX94384.1 - 2.2e-17 63.2 0.7 2.7e-17 62.9 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORX94384.1 - 0.04 14.2 1.1 0.054 13.7 1.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I DUF3268 PF11672.8 ORX94384.1 - 0.041 14.2 2.4 0.19 12.0 0.2 2.2 1 1 0 2 2 2 0 zinc-finger-containing domain Cyclin PF08613.11 ORX94385.1 - 9.7e-14 52.0 0.0 1.2e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX94385.1 - 8.7e-07 28.7 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain UBA_2 PF08587.11 ORX94386.1 - 0.0016 18.5 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin associated domain (UBA) PRiA4_ORF3 PF07929.11 ORX94387.1 - 6e-12 45.6 0.0 4.1e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF2249 PF10006.9 ORX94387.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) EF-hand_1 PF00036.32 ORX94388.1 - 2.5e-26 89.2 10.5 1e-07 31.0 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORX94388.1 - 3.1e-23 82.0 3.0 2.4e-13 50.3 0.9 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX94388.1 - 6e-21 72.5 6.9 2.4e-05 23.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORX94388.1 - 5.2e-19 66.8 15.7 1.2e-07 30.9 0.6 4.6 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORX94388.1 - 2.6e-13 49.6 16.1 0.00014 21.7 0.6 4.2 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX94388.1 - 1.1e-05 25.7 0.0 0.0014 19.0 0.0 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORX94388.1 - 2.6e-05 24.1 6.6 0.098 12.6 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORX94388.1 - 0.0056 17.0 0.2 0.58 10.5 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 ORX94388.1 - 0.16 12.2 2.0 0.96 9.7 1.1 2.5 2 1 1 3 3 3 0 Dockerin type I domain Nse4-Nse3_bdg PF15412.6 ORX94388.1 - 0.23 11.6 2.8 7.3 6.8 0.5 3.4 3 1 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE Exo_endo_phos PF03372.23 ORX94389.1 - 1.1e-25 90.6 0.0 1.9e-25 89.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ORX94389.1 - 0.014 15.2 0.2 0.51 10.2 0.0 2.8 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase GPI-anchored PF10342.9 ORX94390.1 - 4.6e-13 49.7 0.7 2e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mito_carr PF00153.27 ORX94391.1 - 1.2e-50 169.4 4.9 4.3e-18 65.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 ORX94392.1 - 1.4e-82 278.0 0.0 1.6e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 ORX94394.1 - 5.9e-18 64.2 12.3 1.5e-06 28.3 1.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX94394.1 - 5.1e-13 48.7 12.8 6.6e-06 26.5 1.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX94394.1 - 2e-11 43.6 8.3 0.00061 19.7 1.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX94394.1 - 2e-11 43.8 8.8 3.3e-06 27.3 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX94394.1 - 1.1e-06 28.8 4.5 0.0062 16.8 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX94394.1 - 7.2e-05 23.0 10.8 0.004 17.4 2.6 1.7 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 ORX94394.1 - 0.00075 19.7 5.9 0.00097 19.4 1.7 2.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORX94394.1 - 0.0008 19.1 2.0 0.14 11.9 0.2 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 ORX94394.1 - 0.0012 19.5 0.5 0.004 17.8 0.5 1.7 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 ORX94394.1 - 0.0012 19.4 1.6 0.37 11.4 0.2 2.8 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-LYAR PF08790.11 ORX94394.1 - 0.002 18.0 1.6 9.1 6.3 0.0 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 ORX94394.1 - 0.0034 16.9 1.2 0.99 9.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf_ZIC PF18366.1 ORX94394.1 - 0.0045 17.1 2.0 0.36 11.0 0.1 3.0 3 0 0 3 3 3 1 Zic proteins zinc finger domain C1_4 PF07975.12 ORX94394.1 - 0.0053 17.0 4.1 0.5 10.7 3.1 2.2 1 1 1 2 2 2 2 TFIIH C1-like domain zf-H2C2_5 PF13909.6 ORX94394.1 - 0.006 16.3 5.6 0.006 16.3 5.6 3.8 4 1 0 4 4 3 1 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 ORX94394.1 - 0.0068 16.5 0.8 1.7 8.9 0.1 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2HE PF16278.5 ORX94394.1 - 0.0083 16.6 0.6 0.0083 16.6 0.6 2.1 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger TFIIS_C PF01096.18 ORX94394.1 - 0.015 15.1 1.7 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 ORX94394.1 - 0.016 15.1 1.2 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.20 ORX94394.1 - 0.024 14.7 0.4 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Rubredoxin Prok-RING_1 PF14446.6 ORX94394.1 - 0.03 14.2 0.3 8.8 6.3 0.1 2.5 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 XPA_N PF01286.18 ORX94394.1 - 0.035 14.2 4.2 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 XPA protein N-terminal zf-MYST PF17772.1 ORX94394.1 - 0.046 13.3 3.7 0.65 9.6 1.0 2.8 1 1 1 2 2 2 0 MYST family zinc finger domain IBR PF01485.21 ORX94394.1 - 0.056 13.7 3.6 0.21 11.8 0.3 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 ORX94394.1 - 0.058 13.4 6.1 0.1 12.6 6.1 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain LIM PF00412.22 ORX94394.1 - 0.073 13.3 3.6 2.1 8.7 1.9 2.4 1 1 1 2 2 2 0 LIM domain TRAF6_Z2 PF18048.1 ORX94394.1 - 0.075 13.1 0.8 1.3 9.2 0.1 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Evr1_Alr PF04777.13 ORX94394.1 - 0.081 13.4 2.3 3 8.4 0.2 2.2 1 1 1 2 2 2 0 Erv1 / Alr family zf-AN1 PF01428.16 ORX94394.1 - 0.083 13.1 1.0 0.083 13.1 1.0 2.6 2 1 1 3 3 3 0 AN1-like Zinc finger zf-met PF12874.7 ORX94394.1 - 0.18 12.3 4.3 14 6.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Elf1 PF05129.13 ORX94394.1 - 0.21 11.6 3.5 1.8 8.7 3.6 2.0 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like HalOD2 PF18547.1 ORX94394.1 - 0.57 10.1 2.6 9.3 6.2 2.9 2.1 1 1 1 2 2 2 0 Halobacterial output domain 2 zf_C2H2_ZHX PF18387.1 ORX94394.1 - 0.82 9.4 5.8 1.8 8.3 0.2 2.4 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain E1-E2_ATPase PF00122.20 ORX94395.1 - 3.5e-38 130.9 0.1 3.5e-38 130.9 0.1 3.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX94395.1 - 2.3e-17 64.0 0.0 5.5e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX94395.1 - 8.8e-15 54.9 14.4 8.8e-15 54.9 14.4 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 ORX94395.1 - 2.6e-09 36.6 0.0 6.1e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORX94395.1 - 1.7e-08 34.4 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORX94395.1 - 0.0054 16.5 0.1 0.031 14.0 0.0 1.8 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX94395.1 - 0.079 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase COX7C PF02935.16 ORX94395.1 - 0.098 12.9 2.7 0.28 11.5 2.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc RNA_pol_L_2 PF13656.6 ORX94403.1 - 1.9e-31 107.6 0.1 2.3e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORX94403.1 - 1.1e-12 47.1 0.0 1.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain eIF3_N PF09440.10 ORX94404.1 - 2e-51 173.9 4.1 2e-51 173.9 4.1 2.5 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 ORX94404.1 - 2.6e-14 53.6 0.3 5.7e-14 52.5 0.3 1.6 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 ORX94404.1 - 0.0042 17.1 1.7 0.29 11.1 0.0 3.2 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family HIP1_clath_bdg PF16515.5 ORX94404.1 - 0.44 11.2 3.1 4.6 7.9 1.0 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_L6e PF01159.19 ORX94405.1 - 5.4e-42 142.8 0.9 5.4e-42 142.8 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORX94405.1 - 9.6e-09 35.4 0.5 9.6e-09 35.4 0.5 2.3 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain RsgA_GTPase PF03193.16 ORX94406.1 - 1.3e-10 41.4 0.1 1.7e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX94406.1 - 1.9e-10 40.8 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX94406.1 - 5.4e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORX94406.1 - 0.011 15.3 0.4 0.12 11.9 0.4 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.18 ORX94406.1 - 0.012 14.9 0.2 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 ORX94406.1 - 0.021 14.9 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Dynamin family AAA PF00004.29 ORX94406.1 - 0.048 14.1 0.1 0.062 13.7 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORX94406.1 - 0.093 11.9 0.1 0.23 10.6 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 ORX94406.1 - 0.097 13.0 0.1 0.2 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ORX94406.1 - 0.098 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SLC12 PF03522.15 ORX94406.1 - 0.11 11.5 0.2 0.13 11.2 0.2 1.3 1 1 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 ORX94408.1 - 3.7e-45 154.3 2.2 8.5e-38 130.2 0.8 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family CAF1 PF04857.20 ORX94409.1 - 1.8e-79 267.2 0.1 2.2e-79 266.9 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 ORX94409.1 - 3.9e-07 30.0 0.0 1.8e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 RNA binding domain DNA_pol_A_exo1 PF01612.20 ORX94409.1 - 0.031 14.0 0.4 9.4 5.9 0.0 2.7 2 1 0 2 2 2 0 3'-5' exonuclease TAT_signal PF10518.9 ORX94410.1 - 0.0042 16.9 0.7 0.008 16.0 0.7 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence RhoGAP PF00620.27 ORX94411.1 - 8.1e-39 132.9 0.1 2.9e-38 131.1 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 ORX94411.1 - 0.019 15.3 0.4 0.019 15.3 0.4 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TBK1_ULD PF18396.1 ORX94411.1 - 0.058 13.3 0.2 0.15 12.0 0.2 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain zf-C4H2 PF10146.9 ORX94411.1 - 9.7 6.4 10.3 0.44 10.8 2.4 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Peptidase_S8 PF00082.22 ORX94412.1 - 1.4e-51 175.6 0.9 2.1e-51 175.0 0.9 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORX94412.1 - 1.1e-16 61.5 0.4 2.7e-16 60.3 0.4 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORX94412.1 - 4.4e-06 26.6 2.1 1.1e-05 25.3 0.1 2.7 3 0 0 3 3 3 1 PA domain Inhibitor_I9 PF05922.16 ORX94412.1 - 0.0037 17.9 0.1 0.0094 16.6 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4232 PF14016.6 ORX94412.1 - 0.0074 16.4 0.3 0.0074 16.4 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4232) Fn3-like PF14310.6 ORX94412.1 - 0.026 14.6 0.2 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Fibronectin type III-like domain DUF2729 PF10870.8 ORX94413.1 - 0.0068 16.3 0.0 0.092 12.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2729) Exo_endo_phos PF03372.23 ORX94414.1 - 1.4e-17 64.0 0.0 5.9e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family STIMATE PF12400.8 ORX94432.1 - 4.2e-35 121.0 6.5 6.1e-35 120.5 6.5 1.3 1 0 0 1 1 1 1 STIMATE family Ost5 PF05251.12 ORX94433.1 - 1.1e-18 67.2 7.3 1.2e-18 67.1 7.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF1422 PF07226.11 ORX94433.1 - 0.0038 17.2 0.3 0.0049 16.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1422) Lung_7-TM_R PF06814.13 ORX94434.1 - 6.6e-08 32.2 8.2 1.4e-07 31.1 8.2 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 ORX94434.1 - 0.00027 20.5 1.0 0.00027 20.5 1.0 2.0 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF5090 PF17009.5 ORX94434.1 - 0.69 9.8 3.6 1.7 8.5 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Phtf-FEM1B_bdg PF12129.8 ORX94434.1 - 7.4 6.4 8.7 0.47 10.3 2.3 2.0 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Ras PF00071.22 ORX94435.1 - 2.6e-53 180.0 0.0 2.9e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX94435.1 - 9.2e-19 67.8 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX94435.1 - 1.6e-06 27.7 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX94435.1 - 0.11 12.0 0.0 1.3 8.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Tubulin PF00091.25 ORX94436.1 - 1.2e-69 234.5 0.0 2.1e-69 233.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX94436.1 - 5e-46 156.0 0.7 8.6e-46 155.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORX94436.1 - 2.6e-05 24.5 0.0 5.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORX94436.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4430 PF14478.6 ORX94436.1 - 0.062 13.9 0.0 2.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) DUF3818 PF12825.7 ORX94437.1 - 8.4e-77 258.5 7.0 8.4e-77 258.5 7.0 1.8 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORX94437.1 - 9.7e-13 48.2 5.4 4.5e-12 46.1 5.4 2.2 1 1 0 1 1 1 1 PX-associated PX PF00787.24 ORX94437.1 - 1.2e-12 47.8 0.9 4.5e-12 46.0 0.1 2.5 2 0 0 2 2 2 1 PX domain SRI PF08236.11 ORX94437.1 - 0.55 10.4 0.0 0.55 10.4 0.0 3.2 4 0 0 4 4 4 0 SRI (Set2 Rpb1 interacting) domain Aldedh PF00171.22 ORX94438.1 - 9.9e-190 630.9 0.1 1.1e-189 630.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORX94438.1 - 0.039 13.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Sulf_coat_C PF12193.8 ORX94438.1 - 0.13 12.4 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Sulfolobus virus coat protein C terminal Pmp3 PF01679.17 ORX94439.1 - 2.4e-22 78.8 7.5 2.8e-22 78.7 7.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UQ_con PF00179.26 ORX94440.1 - 2.8e-40 137.2 0.1 3.5e-40 136.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX94440.1 - 0.0044 17.3 0.1 0.006 16.9 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 ORX94440.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF4160 PF13711.6 ORX94440.1 - 0.072 13.4 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Perilipin PF03036.16 ORX94441.1 - 6.6e-12 45.2 0.1 8.8e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 Perilipin family SMK-1 PF04802.15 ORX94442.1 - 3.7e-75 252.0 4.5 6.9e-75 251.1 4.5 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Omega_Repress PF07764.11 ORX94442.1 - 0.031 14.9 0.1 0.08 13.5 0.1 1.7 1 0 0 1 1 1 0 Omega Transcriptional Repressor Glyco_transf_20 PF00982.21 ORX94443.1 - 1.9e-157 524.8 0.0 2.5e-157 524.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORX94443.1 - 2.1e-72 243.1 0.0 3.5e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Filo_VP35 PF02097.15 ORX94443.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Kelch_1 PF01344.25 ORX94444.1 - 2.3e-43 145.5 11.1 1.1e-07 31.3 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ORX94444.1 - 2e-42 142.6 9.6 2.7e-08 33.6 0.6 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 ORX94444.1 - 6e-42 141.4 10.6 7.9e-08 32.2 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 ORX94444.1 - 8.1e-40 134.4 14.2 1.3e-09 38.1 0.1 7.3 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX94444.1 - 3.3e-39 131.9 10.5 1.4e-06 28.4 0.0 6.5 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 ORX94444.1 - 3.5e-32 109.1 7.9 3.3e-08 33.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 ORX94444.1 - 0.0068 16.9 6.7 63 4.2 0.2 5.5 6 0 0 6 6 6 0 PQQ-like domain Phosphoesterase PF04185.14 ORX94445.1 - 7.2e-29 101.1 0.7 9.5e-28 97.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoesterase family Pirin PF02678.16 ORX94446.1 - 1.5e-29 102.1 1.3 1.5e-29 102.1 1.3 2.0 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 ORX94446.1 - 1.9e-15 56.8 0.1 1e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 ORX94446.1 - 2.8e-05 23.7 3.3 8e-05 22.3 2.0 2.1 2 1 0 2 2 2 1 Cupin domain Oxysterol_BP PF01237.18 ORX94447.1 - 1e-73 248.4 2.8 2.7e-71 240.4 2.8 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Dpoe2NT PF12213.8 ORX94447.1 - 0.071 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Metallophos_2 PF12850.7 ORX94447.1 - 0.11 12.7 0.1 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain HDAC4_Gln PF12203.8 ORX94447.1 - 0.15 12.2 1.6 0.25 11.5 1.6 1.2 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 Gti1_Pac2 PF09729.9 ORX94448.1 - 2.7e-47 161.2 3.5 1.5e-40 139.2 0.3 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Protamine_3 PF08188.11 ORX94448.1 - 0.23 11.7 0.2 0.23 11.7 0.2 1.7 2 0 0 2 2 2 0 Spermatozal protamine family Fe-S_biosyn PF01521.20 ORX94449.1 - 8.1e-12 45.3 0.0 2.4e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis UCH PF00443.29 ORX94450.1 - 2.9e-65 220.3 0.0 3.3e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX94450.1 - 8.2e-17 61.8 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORX94450.1 - 0.0028 17.2 1.0 0.056 12.9 0.4 2.6 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_S10 PF00450.22 ORX94452.1 - 2.7e-109 366.4 0.1 3.3e-109 366.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GDP_Man_Dehyd PF16363.5 ORX94453.1 - 5.3e-157 522.4 0.1 6e-157 522.2 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX94453.1 - 2.2e-72 243.4 0.1 2.8e-72 243.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX94453.1 - 0.00016 20.8 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORX94453.1 - 0.012 14.8 0.0 0.036 13.2 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Polyketide_cyc2 PF10604.9 ORX94475.1 - 5.8e-10 39.6 0.4 6.5e-10 39.4 0.4 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Aha1_N PF09229.11 ORX94476.1 - 1.4e-39 135.5 2.1 3e-39 134.4 2.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORX94476.1 - 9.8e-10 38.7 1.1 2.6e-09 37.4 0.2 2.2 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein FRD2 PF03197.13 ORX94476.1 - 0.08 13.2 0.1 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage FRD2 protein CRAL_TRIO PF00650.20 ORX94477.1 - 1.1e-36 126.0 0.0 1.7e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORX94477.1 - 8.7e-11 41.8 0.1 2.2e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Septin PF00735.18 ORX94478.1 - 1.7e-110 368.8 0.2 2e-110 368.5 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORX94478.1 - 2.5e-10 40.5 0.4 4.4e-10 39.6 0.4 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORX94478.1 - 4e-06 26.3 0.0 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 ORX94478.1 - 5.6e-06 26.5 0.5 0.064 13.3 0.1 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORX94478.1 - 1.7e-05 24.8 1.8 0.0002 21.3 0.8 2.4 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORX94478.1 - 2.8e-05 23.8 1.2 0.0043 16.6 0.3 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORX94478.1 - 0.0014 19.1 0.0 0.0026 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX94478.1 - 0.0018 18.6 0.0 0.0034 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain IIGP PF05049.13 ORX94478.1 - 0.0024 17.0 0.5 0.0073 15.4 0.1 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) T2SSE PF00437.20 ORX94478.1 - 0.0031 16.6 0.2 0.005 15.9 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Ras PF00071.22 ORX94478.1 - 0.0036 16.9 0.1 0.011 15.4 0.1 1.8 1 1 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.18 ORX94478.1 - 0.0047 16.3 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.27 ORX94478.1 - 0.006 17.1 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 ORX94478.1 - 0.007 15.6 0.2 0.011 14.9 0.2 1.4 1 1 0 1 1 1 1 NB-ARC domain Roc PF08477.13 ORX94478.1 - 0.0097 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORX94478.1 - 0.013 15.1 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORX94478.1 - 0.016 15.5 0.2 0.15 12.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORX94478.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 ORX94478.1 - 0.027 14.5 0.7 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Lig_chan-Glu_bd PF10613.9 ORX94478.1 - 0.038 14.2 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site DUF1542 PF07564.11 ORX94478.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) AAA_29 PF13555.6 ORX94478.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 ORX94478.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORX94478.1 - 0.1 12.3 0.1 0.25 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain CENP-H PF05837.12 ORX94479.1 - 2.9e-15 56.6 0.8 2.9e-15 56.6 0.8 2.0 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Ada3 PF10198.9 ORX94479.1 - 0.26 11.4 3.8 0.12 12.6 0.9 1.8 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 FSH1 PF03959.13 ORX94480.1 - 2.5e-49 167.8 0.0 3.1e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 ORX94480.1 - 0.00097 19.0 0.0 0.00099 19.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 ORX94480.1 - 0.039 13.8 0.0 0.086 12.6 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORX94480.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LEA_2 PF03168.13 ORX94481.1 - 1.5e-05 25.4 0.1 2.9e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Late embryogenesis abundant protein Acetyltransf_1 PF00583.25 ORX94482.1 - 6.5e-08 32.8 0.0 9.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX94482.1 - 3.4e-05 24.2 0.0 6.2e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX94482.1 - 0.00024 21.0 0.0 0.00069 19.5 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 ORX94482.1 - 0.0015 19.2 0.0 0.002 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORX94482.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HAMP PF00672.25 ORX94483.1 - 4.7e-152 494.4 33.1 2.9e-08 33.9 0.0 20.4 19 1 1 20 20 20 18 HAMP domain HATPase_c PF02518.26 ORX94483.1 - 9.2e-30 103.4 0.1 3.9e-29 101.4 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX94483.1 - 1.3e-25 89.7 0.5 8e-25 87.2 0.5 2.6 1 0 0 1 1 1 1 Response regulator receiver domain APG17 PF04108.12 ORX94483.1 - 6.9e-20 71.5 16.7 0.0019 17.4 0.3 9.7 1 1 8 11 11 11 9 Autophagy protein Apg17 HMG_box PF00505.19 ORX94483.1 - 1.1e-19 70.6 0.5 43 4.6 0.0 14.7 15 0 0 15 15 15 0 HMG (high mobility group) box HisKA PF00512.25 ORX94483.1 - 1.6e-17 63.3 0.5 2.4e-16 59.5 0.5 3.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 ORX94483.1 - 5.8e-17 62.0 0.2 10 6.4 0.0 15.9 19 0 0 19 19 18 0 Domain of unknown function (DUF4279) WXG100 PF06013.12 ORX94483.1 - 6.1e-14 52.0 43.7 0.43 10.8 0.1 18.3 17 3 2 20 20 19 3 Proteins of 100 residues with WXG HTH_6 PF01418.17 ORX94483.1 - 1.1e-11 44.5 3.1 1.4e+02 2.6 0.0 14.1 15 0 0 15 15 14 0 Helix-turn-helix domain, rpiR family DUF1843 PF08898.10 ORX94483.1 - 5.5e-10 39.6 24.0 40 4.8 0.1 15.8 17 0 0 17 17 17 0 Domain of unknown function (DUF1843) CENP-F_leu_zip PF10473.9 ORX94483.1 - 6.3e-07 29.5 55.8 9.3 6.3 0.0 18.3 20 0 0 20 20 20 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GatB_Yqey PF02637.18 ORX94483.1 - 7e-07 29.2 51.9 8.4 6.3 0.3 16.2 13 4 2 17 17 17 1 GatB domain DUF1759 PF03564.15 ORX94483.1 - 1.3e-05 25.2 25.2 65 3.4 0.0 14.3 17 0 0 17 17 17 0 Protein of unknown function (DUF1759) SpoIIID PF12116.8 ORX94483.1 - 2.4e-05 24.4 30.7 48 4.2 0.0 15.6 16 0 0 16 16 16 0 Stage III sporulation protein D GLE1 PF07817.13 ORX94483.1 - 0.0015 17.8 41.4 17 4.5 0.0 14.2 6 4 10 16 16 16 0 GLE1-like protein ApoLp-III PF07464.11 ORX94483.1 - 0.0021 18.2 101.5 0.54 10.4 1.7 17.1 5 2 13 19 19 18 8 Apolipophorin-III precursor (apoLp-III) AKNA PF12443.8 ORX94483.1 - 0.07 13.8 0.4 0.74 10.5 0.4 2.9 1 0 0 1 1 1 0 AT-hook-containing transcription factor VBS PF08913.10 ORX94483.1 - 0.29 11.6 71.4 21 5.6 0.2 16.4 16 1 1 17 17 17 0 Vinculin Binding Site Baculo_PEP_C PF04513.12 ORX94483.1 - 0.54 10.3 142.5 0.053 13.6 1.9 18.2 5 1 13 20 20 20 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_8 PF06259.12 ORX94483.1 - 1.2 8.8 111.6 3.3 7.3 0.9 17.1 13 4 4 17 17 17 0 Alpha/beta hydrolase WD40 PF00400.32 ORX94487.1 - 3.1e-49 163.9 22.8 2.6e-07 31.2 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 ORX94487.1 - 1.7e-13 50.3 0.0 3.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX94487.1 - 5.1e-10 39.5 2.5 0.051 13.9 0.1 5.5 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX94487.1 - 7.1e-09 35.3 0.1 1.4e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORX94487.1 - 7.8e-09 34.7 3.9 0.16 10.6 0.0 5.8 2 2 4 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ORX94487.1 - 2.9e-08 33.4 3.2 2.1e-05 24.0 0.8 2.1 1 1 1 2 2 2 2 WD40-like domain DUF5046 PF16465.5 ORX94487.1 - 4.5e-05 23.0 0.0 0.13 11.6 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 ORX94487.1 - 0.0039 16.8 0.8 0.86 9.1 0.1 3.4 1 1 3 4 4 4 1 PQQ-like domain PALB2_WD40 PF16756.5 ORX94487.1 - 0.0046 15.9 3.1 3.2 6.6 0.0 4.5 1 1 4 6 6 6 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 ORX94487.1 - 0.1 12.4 0.0 4.2 7.2 0.0 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORX94488.1 - 2.9e-41 138.7 20.6 1.6e-05 25.5 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORX94488.1 - 4.9e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX94488.1 - 3.7e-07 30.4 2.0 1.5 9.2 0.0 5.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX94488.1 - 4.9e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 ORX94488.1 - 1.1e-05 25.5 0.2 0.3 11.1 0.0 4.2 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 ORX94488.1 - 0.0068 15.1 5.8 11 4.5 0.0 5.3 3 1 1 6 6 6 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ORX94488.1 - 0.0096 15.5 0.6 2.8 7.4 0.0 3.1 2 1 2 4 4 4 1 PQQ-like domain WD40_like PF17005.5 ORX94488.1 - 0.014 14.7 0.1 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 ORX94488.1 - 0.036 13.0 0.8 6.8 5.5 0.1 3.2 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain F-box_4 PF15966.5 ORX94488.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box NtA PF03146.15 ORX94488.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Agrin NtA domain DUF2255 PF10012.9 ORX94488.1 - 0.081 13.1 0.2 0.43 10.8 0.1 2.3 2 0 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2255) PQQ PF01011.21 ORX94488.1 - 0.21 11.6 0.5 2.7 8.1 0.1 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat Sulfatase PF00884.23 ORX94490.1 - 3.5e-58 197.4 0.6 5.6e-58 196.8 0.6 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ORX94490.1 - 0.001 18.7 0.8 0.15 11.6 0.2 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphoesterase PF04185.14 ORX94490.1 - 0.012 14.9 0.1 0.016 14.4 0.1 1.5 1 1 0 1 1 1 0 Phosphoesterase family DUF229 PF02995.17 ORX94490.1 - 0.027 13.1 0.0 0.047 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Trm5_N PF18093.1 ORX94490.1 - 0.091 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain Ras_bdg_2 PF14847.6 ORX94490.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PDZ_1 PF12812.7 ORX94491.1 - 1.1e-32 111.9 0.0 1.3e-20 73.2 0.0 3.0 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORX94491.1 - 1e-20 75.1 0.0 1.3e-16 61.8 0.0 2.6 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ORX94491.1 - 6e-17 61.2 0.3 3.5e-06 26.8 0.1 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 ORX94491.1 - 8.8e-14 51.6 0.2 0.00011 22.5 0.1 4.4 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 ORX94491.1 - 7.1e-10 39.1 0.1 0.025 14.9 0.1 3.7 3 0 0 3 3 3 3 PDZ domain MCR_beta_N PF02783.15 ORX94491.1 - 0.021 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain PDZ_3 PF17815.1 ORX94491.1 - 0.2 11.5 0.1 1.1e+02 2.6 0.0 3.8 4 0 0 4 4 4 0 PDZ domain Peptidase_M28 PF04389.17 ORX94492.1 - 3.3e-42 144.4 0.0 4.7e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX94492.1 - 5.4e-16 58.4 0.5 1.5e-15 57.0 0.5 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX94492.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORX94492.1 - 0.0009 18.3 0.0 0.08 12.0 0.0 2.8 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 ORX94493.1 - 2.8e-42 144.7 0.0 4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX94493.1 - 5.5e-16 58.4 0.5 1.5e-15 57.0 0.5 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 ORX94493.1 - 8.2e-05 21.8 0.0 0.008 15.2 0.0 2.8 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORX94493.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Tetraspanin PF00335.20 ORX94494.1 - 5.3e-07 29.6 9.0 6.9e-07 29.2 9.0 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3169 PF11368.8 ORX94494.1 - 0.013 15.0 1.5 0.013 15.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) MitoNEET_N PF10660.9 ORX94494.1 - 0.025 14.6 0.2 0.062 13.3 0.2 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3261 PF11659.8 ORX94494.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) PRA1 PF03208.19 ORX94494.1 - 1.5 8.5 8.6 0.26 10.9 0.4 2.4 2 1 0 2 2 2 0 PRA1 family protein LapA_dom PF06305.11 ORX94494.1 - 9.2 6.2 6.6 2.4 8.0 0.1 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain HGTP_anticodon PF03129.20 ORX94495.1 - 1.7e-21 76.2 0.0 5.8e-21 74.5 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORX94495.1 - 4.5e-09 36.5 0.1 1.9e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PhzC-PhzF PF02567.16 ORX94496.1 - 2e-56 191.5 0.0 2.3e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein E2F_CC-MB PF16421.5 ORX94496.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain Pilus_CpaD PF09476.10 ORX94496.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Ribosomal_L24e PF01246.20 ORX94497.1 - 4.2e-33 113.4 0.3 4.2e-33 113.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CDPS PF16715.5 ORX94497.1 - 0.43 10.2 5.7 0.62 9.7 5.7 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase DDHD PF02862.17 ORX94497.1 - 1.5 9.0 5.0 1.8 8.6 5.0 1.0 1 0 0 1 1 1 0 DDHD domain FMN_red PF03358.15 ORX94498.1 - 6.9e-12 45.4 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX94498.1 - 0.00095 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORX94498.1 - 0.011 15.9 0.1 0.025 14.8 0.0 1.7 2 1 0 2 2 2 0 Flavodoxin FMN_red PF03358.15 ORX94499.1 - 1.3e-05 25.0 0.0 3.2e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX94499.1 - 0.02 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold FMN_red PF03358.15 ORX94500.1 - 7.1e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX94500.1 - 0.0011 18.8 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORX94500.1 - 0.011 15.9 0.1 0.025 14.8 0.0 1.7 2 1 0 2 2 2 0 Flavodoxin SecIII_SopE_N PF05364.14 ORX94500.1 - 0.13 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus FMN_red PF03358.15 ORX94501.1 - 8.2e-12 45.1 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 ORX94501.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.17 ORX94501.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold FMN_red PF03358.15 ORX94502.1 - 4.7e-12 45.9 0.0 8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX94502.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORX94502.1 - 0.0098 16.1 0.0 0.022 15.0 0.0 1.7 2 1 0 2 2 2 1 Flavodoxin FMN_red PF03358.15 ORX94503.1 - 1.3e-12 47.7 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORX94503.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORX94503.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin ANAPC15 PF15243.6 ORX94504.1 - 0.016 15.6 28.2 2 8.9 28.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 MPM1 PF17234.2 ORX94504.1 - 0.029 14.6 6.5 0.044 14.0 6.5 1.3 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Tim54 PF11711.8 ORX94504.1 - 0.26 10.0 6.0 0.28 9.9 6.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 IF4E PF01652.18 ORX94505.1 - 6.2e-56 188.6 0.1 7.7e-56 188.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 ORX94506.1 - 2.6e-12 47.0 15.6 0.0087 16.9 1.2 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat Dynein_IC2 PF11540.8 ORX94506.1 - 0.00012 21.9 0.3 0.0003 20.7 0.3 1.7 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 CAF1 PF04857.20 ORX94506.1 - 0.0038 16.5 0.3 0.0057 15.9 0.3 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease ANAPC4_WD40 PF12894.7 ORX94506.1 - 0.093 13.0 0.0 3.9 7.8 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF572 PF04502.13 ORX94506.1 - 0.15 11.7 8.3 0.036 13.7 4.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Rsa3 PF14615.6 ORX94507.1 - 2.8e-17 62.0 0.6 6.8e-17 60.8 0.6 1.7 1 0 0 1 1 1 1 Ribosome-assembly protein 3 baeRF_family10 PF18854.1 ORX94508.1 - 0.087 13.1 0.3 0.13 12.6 0.3 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 B12D PF06522.11 ORX94509.1 - 3e-17 62.2 0.1 3.9e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF4262 PF14081.6 ORX94509.1 - 0.13 12.5 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) AA_permease PF00324.21 ORX94510.1 - 5.3e-135 450.7 42.2 6.4e-135 450.4 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX94510.1 - 1.3e-44 152.7 46.5 1.8e-44 152.3 46.5 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_2 PF13347.6 ORX94511.1 - 4.4e-10 38.7 5.4 4.4e-10 38.7 5.4 2.3 3 1 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 ORX94511.1 - 0.00038 19.6 1.2 0.00038 19.6 1.2 1.6 2 0 0 2 2 2 1 PUCC protein DUF2417 PF10329.9 ORX94511.1 - 7.6 5.9 12.8 3.4 7.0 6.2 3.0 2 1 0 2 2 2 0 Region of unknown function (DUF2417) HSF_DNA-bind PF00447.17 ORX94512.1 - 3e-31 107.9 4.9 3e-31 107.9 4.9 2.1 2 1 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 ORX94512.1 - 1.8e-24 86.0 1.1 4.7e-24 84.7 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GOLGA2L5 PF15070.6 ORX94512.1 - 0.0044 15.7 3.1 0.0062 15.3 3.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 AATF-Che1 PF13339.6 ORX94512.1 - 0.89 10.2 5.5 0.85 10.3 3.4 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Response_reg PF00072.24 ORX94513.1 - 2.7e-26 91.9 0.3 6.7e-26 90.7 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORX94513.1 - 3.2e-22 78.3 1.3 6.9e-22 77.3 0.6 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 ORX94513.1 - 1.3e-21 77.2 0.2 2.6e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 ORX94513.1 - 9.4e-08 32.8 0.0 5.9e-07 30.2 0.0 2.3 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 ORX94513.1 - 1.9e-05 25.0 0.0 9.4e-05 22.7 0.0 2.2 3 0 0 3 3 3 1 GAF domain HATPase_c_5 PF14501.6 ORX94513.1 - 0.0029 17.5 0.5 0.018 14.9 0.0 2.5 3 0 0 3 3 3 1 GHKL domain HATPase_c_3 PF13589.6 ORX94513.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 ORX94513.1 - 0.068 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain ACT_7 PF13840.6 ORX94525.1 - 1.1e-26 92.4 0.0 3.7e-16 58.7 0.0 2.6 3 0 0 3 3 3 2 ACT domain Castor1_N PF18700.1 ORX94525.1 - 2.3e-11 43.3 0.4 6.2e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT PF01842.25 ORX94525.1 - 0.00013 21.7 0.0 0.22 11.3 0.0 2.8 2 1 0 2 2 2 2 ACT domain SIP1 PF04938.12 ORX94526.1 - 1.9e-47 161.8 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SCAN PF02023.17 ORX94526.1 - 0.41 10.5 3.3 13 5.7 0.2 3.0 1 1 2 3 3 3 0 SCAN domain NICE-3 PF07406.11 ORX94527.1 - 0.18 11.8 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 NICE-3 protein Stevor PF17410.2 ORX94527.1 - 0.32 10.5 1.1 0.49 9.9 1.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Microvir_J PF04726.13 ORX94527.1 - 0.35 10.9 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Microvirus J protein Cu-oxidase PF00394.22 ORX94528.1 - 7.5e-40 136.6 0.1 9.5e-38 129.8 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX94528.1 - 1e-32 112.6 0.6 1.6e-31 108.8 0.1 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX94528.1 - 4e-19 68.7 0.1 3.3e-14 52.8 0.0 3.6 3 1 0 3 3 3 3 Multicopper oxidase Kinetochor_Ybp2 PF08568.10 ORX94529.1 - 8.3e-09 34.5 0.8 1e-08 34.2 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Myb_DNA-binding PF00249.31 ORX94530.1 - 8.7e-47 157.1 11.6 5.3e-16 58.5 0.4 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX94530.1 - 3.3e-39 132.9 7.8 1.1e-17 64.0 0.1 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain zf-C2H2 PF00096.26 ORX94530.1 - 1.4e-07 31.5 18.9 0.013 15.9 2.2 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORX94530.1 - 1.8e-05 25.0 11.0 0.014 15.5 2.0 3.4 2 2 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORX94530.1 - 0.00023 21.7 24.0 0.2 12.6 1.5 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger SLIDE PF09111.10 ORX94530.1 - 0.00055 19.9 0.1 2.1 8.4 0.0 3.8 1 1 2 4 4 4 1 SLIDE Rap1_C PF11626.8 ORX94530.1 - 0.00067 19.7 4.0 0.18 11.9 0.2 3.2 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_8 PF15909.5 ORX94530.1 - 0.0026 18.0 2.1 0.2 12.0 0.3 3.0 2 1 0 2 2 2 1 C2H2-type zinc ribbon MADF_DNA_bdg PF10545.9 ORX94530.1 - 0.0043 17.3 8.1 3.3 8.1 0.3 3.8 4 0 0 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 ORX94530.1 - 0.0094 16.3 6.1 0.23 11.9 0.4 3.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORX94530.1 - 0.13 12.2 2.5 3.2 7.7 0.2 3.1 2 1 0 3 3 3 0 Myb DNA-binding like zf-C2H2_jaz PF12171.8 ORX94530.1 - 0.72 10.2 4.3 22 5.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORX94530.1 - 0.87 10.1 0.1 0.68 10.5 0.3 5.2 6 0 0 6 6 5 0 Zinc-finger double domain zf-RRN7 PF11781.8 ORX94530.1 - 4.3 7.1 7.5 43 3.9 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Yae1_N PF09811.9 ORX94531.1 - 4e-09 36.0 25.9 0.00074 19.2 6.3 3.5 1 1 2 3 3 3 3 Essential protein Yae1, N terminal CENP-T_C PF15511.6 ORX94533.1 - 1.9e-08 34.4 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORX94533.1 - 2.8e-05 24.2 0.1 4e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORX94533.1 - 6.3e-05 23.4 0.2 7.2e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX94533.1 - 9.2e-05 22.8 0.1 0.00012 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX94533.1 - 0.00013 22.1 0.1 0.00024 21.3 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX94533.1 - 0.022 14.8 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX94533.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORX94533.1 - 0.18 12.3 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Peptidase_M24 PF00557.24 ORX94534.1 - 9.3e-62 208.4 0.0 1.2e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORX94534.1 - 4.5e-19 68.4 0.0 8.7e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pirin PF02678.16 ORX94535.1 - 1.9e-31 108.3 0.1 3.7e-31 107.3 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORX94535.1 - 7.9e-29 100.1 0.0 1.8e-27 95.7 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORX94535.1 - 0.00098 18.8 2.8 0.035 13.8 1.1 2.4 2 0 0 2 2 2 2 Cupin domain TMEM52 PF14979.6 ORX94536.1 - 0.24 11.3 0.7 2.5 8.0 0.0 2.0 1 1 1 2 2 2 0 Transmembrane 52 Metallothio_PEC PF02068.16 ORX94538.1 - 1.7 9.0 116.1 0.089 13.1 15.1 4.3 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX94539.1 - 0.04 14.3 14.2 0.04 14.3 14.2 4.3 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX94540.1 - 0.011 16.1 32.5 0.011 16.1 32.5 4.3 1 1 3 4 4 4 0 Plant PEC family metallothionein Metallothio_PEC PF02068.16 ORX94541.1 - 0.013 15.8 32.4 0.013 15.8 32.4 4.3 1 1 3 4 4 4 0 Plant PEC family metallothionein Uricase PF01014.18 ORX94542.1 - 5.8e-63 211.0 3.6 1.2e-35 122.6 1.4 2.2 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORX94543.1 - 3.8e-60 201.9 4.5 7.7e-36 123.2 2.5 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORX94543.1 - 0.00072 20.1 0.9 0.01 16.3 0.6 2.3 2 0 0 2 2 2 1 Dihydroneopterin aldolase DHODB_Fe-S_bind PF10418.9 ORX94555.1 - 0.022 14.5 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Pep3_Vps18 PF05131.14 ORX94557.1 - 2.1e-52 176.9 0.0 6.7e-52 175.3 0.0 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 ORX94557.1 - 1.9e-10 40.8 3.5 1.9e-10 40.8 3.5 3.7 3 1 0 3 3 3 1 Region in Clathrin and VPS DUF2175 PF09943.9 ORX94557.1 - 3.8e-05 23.9 0.7 0.00022 21.4 0.3 2.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.9 ORX94557.1 - 0.00043 20.7 0.1 0.0018 18.7 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 ORX94557.1 - 0.00053 19.6 0.7 0.0011 18.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ORX94557.1 - 0.00055 19.9 1.2 0.0012 18.7 1.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 ORX94557.1 - 0.00088 19.0 3.0 0.002 17.8 3.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORX94557.1 - 0.00095 19.4 0.9 0.0026 18.1 0.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX94557.1 - 0.0049 16.7 2.0 0.013 15.3 2.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX94557.1 - 0.014 15.7 0.3 0.038 14.3 0.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORX94557.1 - 0.038 13.9 1.1 0.091 12.6 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX94557.1 - 0.04 13.9 1.2 0.09 12.8 1.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX94557.1 - 0.095 12.8 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 ORX94557.1 - 0.12 12.7 0.9 1.9 8.8 0.1 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain C6_DPF PF10170.9 ORX94557.1 - 0.13 12.6 0.3 0.34 11.3 0.3 1.7 1 0 0 1 1 1 0 Cysteine-rich domain LMBR1 PF04791.16 ORX94557.1 - 7.5 5.3 6.7 3.2 6.6 2.9 1.9 1 1 0 2 2 2 0 LMBR1-like membrane protein ATP-synt_F PF01990.17 ORX94558.1 - 1.6e-15 57.2 0.4 2e-14 53.7 0.4 2.0 1 1 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Peptidase_S37 PF05576.11 ORX94558.1 - 0.025 13.2 0.0 0.03 13.0 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 HLH PF00010.26 ORX94559.1 - 8.6e-18 64.0 2.1 2e-17 62.9 2.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SOGA PF11365.8 ORX94559.1 - 0.021 16.0 0.4 0.2 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein SOGA TauD PF02668.16 ORX94560.1 - 7.6e-59 199.7 0.2 1e-58 199.3 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PDZ_5 PF17817.1 ORX94562.1 - 0.017 15.4 0.2 0.021 15.1 0.2 1.2 1 0 0 1 1 1 0 PDZ domain SIR2 PF02146.17 ORX94565.1 - 5.4e-34 117.7 0.0 9.4e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family SH3_1 PF00018.28 ORX94566.1 - 3.3e-13 49.0 0.1 5.1e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX94566.1 - 2.6e-11 43.2 0.1 3.7e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX94566.1 - 3.6e-09 36.2 0.0 6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2070 PF09843.9 ORX94566.1 - 7.8 4.7 22.1 9.7 4.3 22.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-C3HC4 PF00097.25 ORX94568.1 - 3.6e-08 33.1 7.2 3.6e-08 33.1 7.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX94568.1 - 6e-08 32.9 9.5 6e-08 32.9 9.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX94568.1 - 2.2e-07 30.6 8.9 2.2e-07 30.6 8.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX94568.1 - 2.3e-07 30.5 7.6 5.1e-07 29.5 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX94568.1 - 1.8e-06 27.9 5.0 1.8e-06 27.9 5.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX94568.1 - 6e-06 26.1 5.7 6e-06 26.1 5.7 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORX94568.1 - 0.00019 21.5 10.3 0.00037 20.6 10.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORX94568.1 - 0.0023 18.2 5.0 0.0023 18.2 5.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX94568.1 - 0.016 15.3 3.8 0.032 14.3 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORX94568.1 - 0.025 14.4 9.1 0.025 14.4 9.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 ORX94568.1 - 0.07 13.1 3.5 0.11 12.4 3.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 ORX94568.1 - 0.081 12.3 1.5 0.1 11.9 0.8 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger Zn_ribbon_17 PF17120.5 ORX94568.1 - 0.17 11.6 7.2 0.3 10.7 7.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Methyltransf_2 PF00891.18 ORX94569.1 - 5.2e-37 127.2 0.0 6.4e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 ORX94569.1 - 9.7e-07 29.5 0.0 5.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX94569.1 - 0.0091 16.7 0.0 0.016 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX94569.1 - 0.038 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ORX94569.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CBM_21 PF03370.13 ORX94570.1 - 2.6e-29 101.6 2.4 2.6e-29 101.6 2.4 1.9 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORX94570.1 - 7.6e-11 42.4 2.6 1.8e-10 41.2 2.6 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) tRNA_SAD PF07973.14 ORX94571.1 - 1.2e-06 28.5 0.1 1.2e-06 28.5 0.1 2.3 3 0 0 3 3 3 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 ORX94571.1 - 8.9e-06 24.5 0.4 1.8e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 ORX94571.1 - 0.016 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 DHHA1 domain DUF4479 PF14794.6 ORX94571.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) GFO_IDH_MocA PF01408.22 ORX94572.1 - 7.5e-21 75.2 0.0 1.3e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX94572.1 - 0.00021 21.3 0.0 0.00067 19.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Kelch_4 PF13418.6 ORX94573.1 - 4.8e-21 74.5 4.2 1.1e-06 28.5 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORX94573.1 - 5.2e-20 70.6 7.5 0.0003 20.6 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 ORX94573.1 - 1.2e-18 66.6 7.1 0.00088 19.5 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 ORX94573.1 - 4.5e-14 52.3 5.4 0.0023 18.2 0.0 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORX94573.1 - 2.3e-13 49.8 12.3 0.0053 16.7 1.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 ORX94573.1 - 4.1e-13 48.7 9.1 0.00016 21.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 ORX94573.1 - 3.9e-11 43.2 0.0 8.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 ORX94573.1 - 0.01 15.9 0.0 0.095 12.8 0.0 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch Sad1_UNC PF07738.13 ORX94575.1 - 9.4e-35 119.5 0.0 1.3e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal zf-C3HC4_3 PF13920.6 ORX94576.1 - 0.00043 20.1 8.1 0.00071 19.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LicD PF04991.13 ORX94576.1 - 0.15 12.2 1.8 0.26 11.4 1.8 1.4 1 0 0 1 1 1 0 LicD family MPM1 PF17234.2 ORX94576.1 - 0.16 12.2 6.2 0.23 11.7 5.6 1.6 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 MRP-S28 PF10213.9 ORX94577.1 - 1e-37 129.4 0.1 1.4e-37 128.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein RF-1 PF00472.20 ORX94577.1 - 0.047 13.6 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 RF-1 domain Cyclin_N PF00134.23 ORX94578.1 - 9.3e-14 51.3 0.0 1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX94578.1 - 1.7e-11 44.7 0.0 2.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Caleosin PF05042.13 ORX94579.1 - 6e-75 250.8 0.2 7.7e-75 250.5 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 ORX94579.1 - 8.3e-06 25.3 1.6 0.32 11.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORX94579.1 - 0.00018 20.8 3.0 0.4 10.3 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ORX94579.1 - 0.00086 19.7 0.2 2.4 8.7 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORX94579.1 - 0.0028 17.1 0.3 0.093 12.3 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORX94579.1 - 0.13 12.2 3.1 1.4 8.8 0.1 2.8 2 1 0 2 2 2 0 EF-hand domain pair FA_hydroxylase PF04116.13 ORX94580.1 - 1.1e-26 93.7 23.0 1.1e-26 93.7 23.0 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RhoGAP PF00620.27 ORX94581.1 - 3.6e-35 121.0 0.0 6.9e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 ORX94581.1 - 2.2e-33 115.3 1.7 5.8e-33 114.0 0.7 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORX94581.1 - 0.0003 20.6 0.5 0.002 17.9 0.4 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain DUF1586 PF07625.11 ORX94582.1 - 6.7 6.9 5.9 12 6.1 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) Glyco_hydro_46 PF01374.18 ORX94583.1 - 3.3e-33 115.1 0.1 3.9e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 GCP_C_terminal PF04130.13 ORX94584.1 - 4.9e-39 134.6 6.3 8.1e-39 133.9 6.3 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORX94584.1 - 1e-29 104.2 0.1 2.1e-29 103.2 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Chitin_bind_1 PF00187.19 ORX94585.1 - 8.3e-08 32.6 19.6 1.6e-07 31.7 19.6 1.4 1 0 0 1 1 1 1 Chitin recognition protein T6SS_HCP PF05638.12 ORX94585.1 - 0.0065 16.9 0.5 0.011 16.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp SOG2 PF10428.9 ORX94585.1 - 0.013 14.7 13.7 0.015 14.5 13.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 ORX94585.1 - 4.4 5.8 14.9 5.1 5.6 14.9 1.0 1 0 0 1 1 1 0 Hamartin protein Connexin PF00029.19 ORX94586.1 - 0.012 15.4 0.2 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 Connexin SWIRM-assoc_2 PF16496.5 ORX94586.1 - 0.82 8.5 8.7 0.37 9.6 3.1 2.0 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal RNase_P_pop3 PF08228.11 ORX94587.1 - 1.8e-10 41.1 0.0 3e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 Arrestin_C PF02752.22 ORX94588.1 - 5.9e-11 43.0 0.7 8.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX94588.1 - 1.9e-05 24.7 0.0 0.00015 21.8 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PNP_UDP_1 PF01048.20 ORX94589.1 - 3.2e-26 92.0 0.0 3.9e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Asp PF00026.23 ORX94590.1 - 8e-104 347.4 4.7 9.6e-104 347.2 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX94590.1 - 3e-14 53.6 6.8 3e-10 40.6 0.5 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORX94590.1 - 0.0004 21.0 0.2 0.011 16.4 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 ORX94590.1 - 0.00072 19.4 0.0 0.0038 17.0 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal He_PIG_assoc PF10632.9 ORX94590.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DNA_pol_B_exo1 PF03104.19 ORX94591.1 - 2.6e-09 36.7 1.0 2.2e-08 33.6 0.2 2.3 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORX94592.1 - 8e-104 347.9 0.1 9.8e-104 347.6 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 ORX94592.1 - 2.7e-14 53.4 6.3 5.1e-14 52.5 6.3 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORX94592.1 - 0.089 11.6 2.0 0.08 11.8 0.3 1.7 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral zf-DBF PF07535.12 ORX94593.1 - 3.4e-13 49.5 0.6 6.4e-13 48.6 0.6 1.5 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.10 ORX94593.1 - 1.1e-06 28.9 0.3 0.015 15.5 0.0 2.7 1 1 1 2 2 2 2 Dfp1/Him1, central region BRCT_2 PF16589.5 ORX94593.1 - 0.011 16.1 0.1 0.053 13.9 0.0 2.1 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORX94593.1 - 0.074 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ABC_tran PF00005.27 ORX94607.1 - 3.2e-48 163.7 3.0 7.3e-26 91.3 0.0 4.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORX94607.1 - 1e-14 55.0 0.7 0.0068 16.2 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX94607.1 - 2.4e-13 50.0 1.0 0.0012 18.3 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX94607.1 - 6.8e-08 33.2 2.4 0.017 15.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX94607.1 - 2e-07 31.1 0.1 0.0076 16.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORX94607.1 - 2.2e-07 30.5 0.0 0.029 14.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 ORX94607.1 - 7.3e-07 29.0 0.3 1.7e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 ORX94607.1 - 2.5e-06 27.8 0.1 0.27 11.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain 4HB PF17947.1 ORX94607.1 - 9.9e-06 25.5 0.0 2.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Four helical bundle domain MMR_HSR1 PF01926.23 ORX94607.1 - 1.1e-05 25.5 0.0 0.11 12.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ORX94607.1 - 1.9e-05 25.2 0.0 0.076 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORX94607.1 - 4.1e-05 23.9 0.1 0.65 10.4 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_22 PF13401.6 ORX94607.1 - 4.5e-05 23.7 0.0 0.046 14.0 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA PF00004.29 ORX94607.1 - 5.6e-05 23.6 0.0 0.13 12.7 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 ORX94607.1 - 7.2e-05 21.9 0.4 0.088 11.8 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ORX94607.1 - 0.00017 22.0 0.0 1 9.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 ORX94607.1 - 0.00024 20.9 0.7 2.2 8.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 ORX94607.1 - 0.00025 21.2 0.0 0.55 10.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 ORX94607.1 - 0.00033 20.6 0.0 0.081 12.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 ORX94607.1 - 0.00054 20.1 0.1 0.033 14.3 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_27 PF13514.6 ORX94607.1 - 0.00091 18.9 0.1 0.81 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORX94607.1 - 0.00096 19.1 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 ORX94607.1 - 0.002 17.9 0.0 0.65 9.6 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 ORX94607.1 - 0.0025 17.6 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORX94607.1 - 0.0026 18.0 0.0 0.15 12.3 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 ORX94607.1 - 0.0076 16.2 0.0 0.97 9.3 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea CLASP_N PF12348.8 ORX94607.1 - 0.013 15.0 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 CLASP N terminal AAA_7 PF12775.7 ORX94607.1 - 0.025 14.1 0.0 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 ORX94607.1 - 0.027 14.7 0.0 7.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 ORX94607.1 - 0.035 14.2 0.0 3.9 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORX94607.1 - 0.038 13.8 0.1 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ORX94607.1 - 0.045 13.7 0.2 6.2 6.7 0.0 2.7 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 ORX94607.1 - 0.057 12.6 0.0 5.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 ORX94607.1 - 0.066 12.9 0.6 4.4 7.0 0.0 3.1 4 0 0 4 4 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 ORX94607.1 - 0.076 13.0 0.2 10 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MukB PF04310.12 ORX94607.1 - 0.1 12.4 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 ORX94607.1 - 0.13 12.2 0.3 15 5.6 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 ORX94607.1 - 0.36 10.5 2.2 18 5.0 0.1 2.7 3 0 0 3 3 2 0 Cytidylate kinase Dynamin_N PF00350.23 ORX94607.1 - 0.68 10.0 3.9 1 9.4 0.0 3.1 4 0 0 4 4 3 0 Dynamin family FHA PF00498.26 ORX94608.1 - 2.2e-18 66.3 0.0 3.7e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORX94608.1 - 2.3e-05 24.6 0.0 0.00084 19.6 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NUDIX PF00293.28 ORX94608.1 - 0.031 14.3 1.0 0.071 13.2 1.0 1.5 1 1 0 1 1 1 0 NUDIX domain DUF4614 PF15391.6 ORX94608.1 - 9.8 6.1 7.0 14 5.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) HLH PF00010.26 ORX94610.1 - 3.1e-16 59.1 1.6 3.1e-16 59.1 1.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FAA_hydrolase PF01557.18 ORX94610.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family HEAT_2 PF13646.6 ORX94611.1 - 6.4e-07 29.7 0.5 0.1 13.0 0.0 6.0 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.22 ORX94611.1 - 0.0002 21.3 0.1 0.052 13.8 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 ORX94611.1 - 0.00025 21.5 0.9 0.065 13.8 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat HBD PF18534.1 ORX94611.1 - 0.0022 18.1 0.0 3 8.0 0.0 4.9 4 0 0 4 4 4 1 Helical bundle domain Cnd1 PF12717.7 ORX94611.1 - 0.007 16.4 8.5 8.3 6.4 0.0 5.6 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 GGA_N-GAT PF18308.1 ORX94611.1 - 0.019 14.6 0.1 4.8 6.9 0.0 3.0 2 0 0 2 2 2 0 GGA N-GAT domain SRPRB PF09439.10 ORX94611.1 - 0.076 12.4 0.3 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RRM_1 PF00076.22 ORX94612.1 - 1.3e-16 60.2 0.1 4.7e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX94612.1 - 5.6e-06 26.0 0.0 6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX94612.1 - 0.12 12.5 0.1 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif Ribosomal_L5_C PF00673.21 ORX94613.1 - 3.6e-28 97.6 0.0 5.8e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORX94613.1 - 3.1e-10 40.2 0.0 5.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Pkinase PF00069.25 ORX94614.1 - 2.1e-48 165.0 0.0 3.7e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94614.1 - 1.5e-19 70.3 0.0 2.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX94614.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX94614.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Hrs_helical PF12210.8 ORX94618.1 - 0.013 16.0 0.1 0.032 14.7 0.1 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SAM_1 PF00536.30 ORX94618.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FR47 PF08445.10 ORX94619.1 - 0.0005 20.0 0.0 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 1 FR47-like protein Aa_trans PF01490.18 ORX94620.1 - 4.4e-63 213.4 19.9 4.4e-63 213.4 19.9 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Arrestin_C PF02752.22 ORX94621.1 - 2.4e-09 37.7 0.0 2.2e-07 31.4 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX94621.1 - 3e-07 30.6 0.0 5.3e-05 23.3 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 ORX94622.1 - 1e-19 70.5 10.9 2.2e-05 25.1 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX94622.1 - 2.4e-08 34.2 0.1 0.035 14.4 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX94622.1 - 0.0019 17.2 0.2 0.97 8.3 0.1 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORX94622.1 - 0.0025 17.2 0.0 2.6 7.3 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain Aminotran_3 PF00202.21 ORX94623.1 - 2.9e-117 391.8 0.1 3.8e-117 391.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORX94623.1 - 1.4e-05 24.5 0.0 0.00016 20.9 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX94623.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PEPCK_ATP PF01293.20 ORX94624.1 - 1.6e-229 762.3 0.0 1.9e-229 762.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORX94625.1 - 4.2e-229 760.9 0.0 4.8e-229 760.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORX94626.1 - 1.6e-229 762.3 0.0 1.8e-229 762.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 ORX94626.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 ORX94627.1 - 6.7e-230 763.6 0.0 7.8e-230 763.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORX94628.1 - 2.2e-230 765.1 0.0 2.6e-230 764.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ribosomal_L2_C PF03947.18 ORX94629.1 - 3.7e-49 166.1 3.1 5.8e-49 165.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORX94629.1 - 5.1e-16 58.4 0.0 1.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PEPCK_ATP PF01293.20 ORX94630.1 - 6.4e-218 724.1 0.0 8.3e-218 723.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORX94631.1 - 1.4e-229 762.5 0.0 1.6e-229 762.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF3472 PF11958.8 ORX94651.1 - 1.1e-12 48.8 1.9 1.6e-12 48.2 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX94651.1 - 7e-08 32.8 12.8 1.4e-07 31.8 12.8 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORX94651.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) DUF4937 PF16291.5 ORX94651.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 MFS_1 PF07690.16 ORX94652.1 - 5.3e-53 180.2 49.3 5.3e-53 180.2 49.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX94652.1 - 3e-16 59.3 12.1 3e-16 59.3 12.1 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORX94652.1 - 2.5e-15 56.0 29.0 3e-15 55.7 29.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ROK PF00480.20 ORX94652.1 - 0.92 8.9 6.8 0.67 9.4 0.1 2.6 2 1 1 3 3 3 0 ROK family CAP PF00188.26 ORX94653.1 - 1.3e-09 39.0 0.2 1.8e-09 38.5 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX94654.1 - 3e-10 41.0 0.2 4.1e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Proteasome PF00227.26 ORX94655.1 - 2.2e-50 170.8 0.0 2.6e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 ORX94655.1 - 1.9e-12 46.3 0.1 1.9e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Kelch_6 PF13964.6 ORX94656.1 - 3.5e-32 109.6 17.1 4.9e-07 29.8 0.2 7.0 3 2 4 7 7 7 6 Kelch motif Kelch_1 PF01344.25 ORX94656.1 - 5.8e-30 102.6 18.9 2.7e-06 26.8 0.1 7.3 7 2 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 ORX94656.1 - 2.7e-26 91.3 10.1 1e-06 28.7 0.0 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORX94656.1 - 3.4e-20 71.6 12.1 3.2e-05 23.8 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 ORX94656.1 - 1.4e-19 69.2 6.1 0.0028 17.6 0.3 7.2 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ORX94656.1 - 6.5e-13 48.6 16.4 1e-05 25.7 0.1 7.3 7 1 0 7 7 7 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 ORX94656.1 - 0.0028 16.9 0.1 0.39 9.9 0.0 2.6 2 2 0 2 2 2 1 Glyoxal oxidase N-terminus zf-C2H2 PF00096.26 ORX94657.1 - 4.8e-13 48.8 9.9 1.2e-06 28.7 2.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX94657.1 - 5.7e-10 39.2 15.4 2.4e-07 30.9 0.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX94657.1 - 1.5e-09 37.9 8.0 5.3e-05 23.7 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX94657.1 - 1.5e-06 28.1 6.6 4.8e-05 23.2 0.9 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX94657.1 - 0.00011 21.9 2.6 0.039 13.7 0.4 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORX94657.1 - 0.00042 20.5 3.2 0.00096 19.4 0.8 2.4 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX94657.1 - 0.00056 20.2 4.2 0.0036 17.6 0.8 2.9 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX94657.1 - 0.0029 17.9 0.9 0.0076 16.5 0.1 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 ORX94657.1 - 0.015 15.4 1.3 3.2 8.0 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-DNA_Pol PF08996.10 ORX94657.1 - 0.023 14.5 0.3 0.024 14.4 0.3 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 ORX94657.1 - 0.1 12.7 2.8 0.88 9.6 2.8 2.1 1 1 0 1 1 1 0 BED zinc finger Zn_ribbon_SprT PF17283.2 ORX94657.1 - 0.13 12.1 7.5 0.17 11.8 2.2 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 ORX94657.1 - 0.42 10.6 0.2 0.42 10.6 0.2 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.7 ORX94657.1 - 0.73 9.9 5.8 1.8 8.6 5.8 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 ORX94657.1 - 0.84 10.1 4.5 1.5 9.4 0.3 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Spermine_synth PF01564.17 ORX94659.1 - 2.5e-70 235.7 0.0 1.3e-69 233.4 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORX94659.1 - 1.4e-23 82.5 0.1 2.4e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ORX94659.1 - 5.9e-05 23.7 0.0 0.00012 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX94659.1 - 0.0065 17.2 0.0 0.016 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORX94659.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 ORX94659.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_2 PF00891.18 ORX94659.1 - 0.044 13.1 0.1 0.12 11.7 0.1 1.8 1 1 1 2 2 2 0 O-methyltransferase domain Glyco_tranf_2_5 PF13712.6 ORX94659.1 - 0.13 11.9 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family MutS_V PF00488.21 ORX94660.1 - 9.1e-35 120.4 0.2 1.2e-34 120.0 0.2 1.2 1 0 0 1 1 1 1 MutS domain V UQ_con PF00179.26 ORX94679.1 - 5.2e-22 78.0 0.0 6.2e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX94679.1 - 0.14 12.4 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain Rep_fac_C PF08542.11 ORX94680.1 - 4.5e-22 78.3 0.1 3.4e-21 75.5 0.0 2.4 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.29 ORX94680.1 - 5.8e-17 62.4 0.0 1.3e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORX94680.1 - 5.2e-16 58.9 0.0 3.5e-12 46.4 0.1 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 ORX94680.1 - 3.6e-07 30.3 0.0 1.5e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 ORX94680.1 - 9.5e-06 25.4 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 ORX94680.1 - 3.6e-05 23.0 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 ORX94680.1 - 5.8e-05 23.0 0.1 0.00099 19.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 ORX94680.1 - 7.4e-05 22.6 0.2 0.00015 21.6 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 ORX94680.1 - 7.9e-05 22.7 0.0 0.00026 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 ORX94680.1 - 0.0001 22.5 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 ORX94680.1 - 0.00015 21.6 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX94680.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORX94680.1 - 0.00025 21.1 0.0 0.028 14.4 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORX94680.1 - 0.00046 20.6 0.0 0.001 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ORX94680.1 - 0.00051 19.6 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 ORX94680.1 - 0.00053 20.3 0.2 0.075 13.3 0.2 2.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORX94680.1 - 0.0028 17.6 0.0 0.0063 16.5 0.0 1.6 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea DEAD PF00270.29 ORX94680.1 - 0.0034 17.2 0.1 0.02 14.6 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 ORX94680.1 - 0.0035 16.8 0.0 0.38 10.1 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 ORX94680.1 - 0.0047 17.3 0.1 0.17 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ORX94680.1 - 0.0064 16.5 0.2 0.082 12.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORX94680.1 - 0.019 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ORX94680.1 - 0.033 13.9 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MutS_III PF05192.18 ORX94680.1 - 0.05 13.8 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 MutS domain III T2SSE PF00437.20 ORX94680.1 - 0.061 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 ORX94680.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORX94680.1 - 0.087 12.2 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.23 ORX94680.1 - 0.092 11.4 0.0 0.2 10.3 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_18 PF13238.6 ORX94680.1 - 0.11 13.0 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Tom22 PF04281.13 ORX94681.1 - 3.1e-32 111.2 2.4 3.7e-32 111.0 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 HMG_box PF00505.19 ORX94682.1 - 6e-16 58.6 1.6 6e-16 58.6 1.6 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX94682.1 - 5.8e-07 30.0 2.6 1.6e-06 28.6 2.6 1.9 1 0 0 1 1 1 1 HMG-box domain F-protein PF00469.20 ORX94682.1 - 1.9 8.0 7.9 2.2 7.8 7.0 1.5 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef V_ATPase_I PF01496.19 ORX94682.1 - 2 6.3 7.8 2.3 6.0 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 ORX94682.1 - 6.9 4.7 12.5 7.1 4.6 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-T_C PF15511.6 ORX94683.1 - 1.9e-08 34.4 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORX94683.1 - 2.8e-05 24.2 0.1 4e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORX94683.1 - 6.3e-05 23.4 0.2 7.2e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX94683.1 - 9.2e-05 22.8 0.1 0.00012 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX94683.1 - 0.00013 22.1 0.1 0.00024 21.3 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX94683.1 - 0.022 14.8 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX94683.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORX94683.1 - 0.18 12.3 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A FAD_binding_1 PF00667.20 ORX94684.1 - 1.6e-57 194.7 0.0 2.5e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX94684.1 - 3.7e-34 118.0 0.1 7e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORX94684.1 - 4.3e-22 78.8 0.0 2.2e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAGLU PF05089.12 ORX94684.1 - 0.021 13.8 0.1 0.043 12.8 0.1 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain HEM4 PF02602.15 ORX94684.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD La PF05383.17 ORX94685.1 - 6.6e-20 70.9 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 La domain Peptidase_C48 PF02902.19 ORX94686.1 - 1.8e-21 77.0 0.2 3.6e-21 76.0 0.2 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3343 PF11823.8 ORX94686.1 - 0.022 14.2 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) DUF4912 PF16258.5 ORX94686.1 - 0.057 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) Hist_deacetyl PF00850.19 ORX94687.1 - 1.1e-83 281.3 0.0 1.4e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain bZIP_1 PF00170.21 ORX94688.1 - 2e-09 37.4 5.8 3.8e-09 36.5 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX94688.1 - 0.00023 21.2 8.0 0.00047 20.2 8.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper NRBF2 PF08961.10 ORX94688.1 - 0.0068 16.0 1.3 0.011 15.3 1.3 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator YojJ PF10372.9 ORX94688.1 - 0.058 13.5 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus YabA PF06156.13 ORX94688.1 - 0.11 13.1 1.4 0.23 12.1 1.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Glutaredoxin2_C PF04399.13 ORX94688.1 - 0.16 11.8 0.5 0.27 11.1 0.5 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain PRKG1_interact PF15898.5 ORX94688.1 - 6 7.8 10.5 0.83 10.6 5.5 2.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mg_trans_NIPA PF05653.14 ORX94689.1 - 1.1e-25 90.4 22.3 2.3e-22 79.5 22.3 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF4083 PF13314.6 ORX94689.1 - 0.052 13.5 0.7 0.052 13.5 0.7 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4083) DUF3328 PF11807.8 ORX94689.1 - 0.78 9.5 2.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DLH PF01738.18 ORX94690.1 - 1.8e-13 50.5 0.0 2.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Leg1 PF05612.12 ORX94690.1 - 0.2 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Leg1 LSM PF01423.22 ORX94691.1 - 9.1e-19 66.9 0.5 1.1e-18 66.6 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORX94691.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Hfq protein UQ_con PF00179.26 ORX94692.1 - 1.2e-48 164.4 0.1 1.3e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX94692.1 - 0.057 13.7 0.7 0.094 13.0 0.7 1.6 1 1 0 1 1 1 0 RWD domain Arf PF00025.21 ORX94693.1 - 8.9e-68 227.2 0.0 9.9e-68 227.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORX94693.1 - 6.4e-11 42.0 0.0 2e-07 30.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORX94693.1 - 2.1e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORX94693.1 - 4.4e-08 33.4 0.0 1e-07 32.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORX94693.1 - 8e-08 32.4 0.0 1.4e-07 31.5 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 ORX94693.1 - 2.3e-07 30.6 0.0 2.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX94693.1 - 4e-06 26.4 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX94693.1 - 0.016 14.7 0.0 0.36 10.3 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 ORX94693.1 - 0.049 13.4 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORX94693.1 - 0.12 12.0 0.0 4.8 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 ORX94693.1 - 0.16 11.5 0.0 6.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Pex14_N PF04695.13 ORX94694.1 - 4.6e-27 95.6 5.8 4.6e-27 95.6 5.8 3.6 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 ORX94694.1 - 0.0002 21.4 6.3 0.00058 19.9 6.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 ORX94694.1 - 0.00043 20.3 7.2 0.00075 19.6 7.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 ORX94694.1 - 0.00072 19.1 8.8 0.00099 18.7 8.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 V_ATPase_I PF01496.19 ORX94694.1 - 0.002 16.2 0.0 0.0022 16.0 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4795 PF16043.5 ORX94694.1 - 0.002 17.8 7.1 0.0037 16.9 7.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF1043 PF06295.12 ORX94694.1 - 0.0073 16.3 13.1 0.03 14.3 13.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1043) DUF745 PF05335.13 ORX94694.1 - 0.0096 15.7 4.5 0.02 14.6 4.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF745) HemX PF04375.14 ORX94694.1 - 0.016 14.5 7.7 0.02 14.2 6.4 1.7 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc7 PF08317.11 ORX94694.1 - 0.018 14.0 11.1 0.026 13.4 11.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMEM247 PF15444.6 ORX94694.1 - 0.022 14.8 0.8 0.034 14.2 0.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 FapA PF03961.13 ORX94694.1 - 0.023 13.3 4.6 0.032 12.8 4.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT57 PF10498.9 ORX94694.1 - 0.024 13.6 11.0 0.036 13.0 11.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.6 ORX94694.1 - 0.024 14.0 11.4 0.041 13.2 11.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 ORX94694.1 - 0.026 14.3 15.6 0.069 13.0 15.6 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 zf-C4H2 PF10146.9 ORX94694.1 - 0.028 14.8 2.3 0.044 14.1 2.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.6 ORX94694.1 - 0.035 13.5 2.8 0.05 12.9 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 ORX94694.1 - 0.035 13.0 1.3 0.054 12.4 1.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 ORX94694.1 - 0.043 13.1 10.0 0.062 12.5 10.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF445 PF04286.12 ORX94694.1 - 0.069 12.9 2.5 0.11 12.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HlyE PF06109.13 ORX94694.1 - 0.083 12.2 0.8 0.32 10.3 0.7 1.8 1 1 1 2 2 2 0 Haemolysin E (HlyE) Laminin_II PF06009.12 ORX94694.1 - 0.11 12.5 7.4 0.041 13.9 4.4 1.8 2 0 0 2 2 1 0 Laminin Domain II Baculo_p24 PF05073.12 ORX94694.1 - 0.15 11.8 3.7 0.23 11.2 3.7 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein TolA_bind_tri PF16331.5 ORX94694.1 - 0.17 12.0 12.6 0.066 13.3 2.6 3.1 1 1 2 3 3 3 0 TolA binding protein trimerisation FlaC_arch PF05377.11 ORX94694.1 - 0.23 11.9 9.7 2.8 8.4 1.6 3.2 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) DUF4164 PF13747.6 ORX94694.1 - 0.26 11.6 7.8 0.74 10.1 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CCDC-167 PF15188.6 ORX94694.1 - 0.27 11.6 12.9 19 5.7 8.5 3.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 ISG65-75 PF11727.8 ORX94694.1 - 0.28 10.4 5.4 0.42 9.8 5.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein EzrA PF06160.12 ORX94694.1 - 0.28 9.3 10.4 0.42 8.7 10.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF641 PF04859.12 ORX94694.1 - 0.29 11.5 8.6 1.1 9.6 8.6 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) CdvA PF18822.1 ORX94694.1 - 0.31 10.9 13.5 1.5 8.7 3.1 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain YojJ PF10372.9 ORX94694.1 - 0.31 11.2 7.1 1.1 9.4 0.4 2.6 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus CCDC84 PF14968.6 ORX94694.1 - 0.46 10.1 4.3 0.6 9.7 4.3 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 DUF948 PF06103.11 ORX94694.1 - 0.48 10.7 11.2 0.19 12.0 3.8 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 ORX94694.1 - 0.51 10.8 10.9 0.79 10.1 10.9 1.2 1 0 0 1 1 1 0 Fez1 UPF0242 PF06785.11 ORX94694.1 - 0.56 10.3 11.3 1.4 9.0 11.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ORX94694.1 - 0.61 10.6 18.1 1.6 9.3 9.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 ORX94694.1 - 0.66 9.8 8.1 1.1 9.1 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.9 ORX94694.1 - 0.68 8.7 9.1 1 8.2 9.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 ORX94694.1 - 0.77 10.3 13.2 1 9.8 1.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Halogen_Hydrol PF10112.9 ORX94694.1 - 0.98 9.4 7.1 1.1 9.2 0.8 3.2 2 1 2 4 4 4 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Jnk-SapK_ap_N PF09744.9 ORX94694.1 - 1 9.6 13.6 1.6 8.9 13.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 COG5 PF10392.9 ORX94694.1 - 1.1 9.4 9.6 2.3 8.4 8.9 1.8 1 1 1 2 2 1 0 Golgi transport complex subunit 5 DUF4349 PF14257.6 ORX94694.1 - 1.1 8.6 8.5 2.2 7.7 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SKA2 PF16740.5 ORX94694.1 - 1.2 9.0 11.0 1.3 8.8 0.6 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Sec20 PF03908.13 ORX94694.1 - 1.2 9.1 8.3 1.4 8.9 6.3 2.0 1 1 1 2 2 2 0 Sec20 CorA PF01544.18 ORX94694.1 - 1.3 8.3 7.8 1.7 7.9 7.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 ORX94694.1 - 1.7 9.3 19.0 2.1 9.0 13.9 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 ORX94694.1 - 1.7 6.5 6.3 2.3 6.1 6.3 1.1 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 ORX94694.1 - 1.8 8.9 15.9 0.89 9.9 3.7 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Nup88 PF10168.9 ORX94694.1 - 1.9 6.2 9.4 2.5 5.8 9.4 1.1 1 0 0 1 1 1 0 Nuclear pore component Seryl_tRNA_N PF02403.22 ORX94694.1 - 2 8.7 12.2 2.7 8.3 2.1 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ALMT PF11744.8 ORX94694.1 - 2 7.2 6.1 3.8 6.2 6.1 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter 5_nucleotid PF05761.14 ORX94694.1 - 2 7.2 6.9 3.1 6.6 6.9 1.2 1 0 0 1 1 1 0 5' nucleotidase family BST2 PF16716.5 ORX94694.1 - 2.8 8.6 18.9 2 9.0 7.1 3.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 RRP36 PF06102.12 ORX94694.1 - 3.1 7.7 13.3 1.5 8.8 10.5 1.7 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 PCRF PF03462.18 ORX94694.1 - 3.2 7.6 9.7 5.8 6.7 9.7 1.3 1 0 0 1 1 1 0 PCRF domain Tup_N PF08581.10 ORX94694.1 - 3.8 7.9 10.8 2 8.8 2.4 2.4 1 1 1 2 2 2 0 Tup N-terminal Fib_alpha PF08702.10 ORX94694.1 - 3.9 7.7 9.6 7.2 6.8 9.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2968 PF11180.8 ORX94694.1 - 4.6 6.8 13.7 5.2 6.7 12.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) FAM76 PF16046.5 ORX94694.1 - 4.7 6.5 7.4 6.3 6.1 7.4 1.1 1 0 0 1 1 1 0 FAM76 protein BshC PF10079.9 ORX94694.1 - 5.2 5.7 9.4 1.7 7.3 3.8 1.9 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC WXG100 PF06013.12 ORX94694.1 - 5.2 7.4 8.2 8.4 6.7 0.4 3.3 3 1 1 4 4 3 0 Proteins of 100 residues with WXG DUF883 PF05957.13 ORX94694.1 - 5.2 7.7 7.6 12 6.5 1.0 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YabA PF06156.13 ORX94694.1 - 7 7.3 11.6 2.3 8.9 6.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF334 PF03904.13 ORX94694.1 - 8.6 5.8 8.7 13 5.3 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) ATG16 PF08614.11 ORX94694.1 - 9.2 6.4 17.9 9 6.5 16.8 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0220 PF05255.11 ORX94695.1 - 2.1e-48 164.0 2.1 2.5e-48 163.7 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ATP1G1_PLM_MAT8 PF02038.16 ORX94695.1 - 4.5 6.8 5.9 16 5.0 0.5 2.8 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Yae1_N PF09811.9 ORX94696.1 - 3.6e-07 29.8 26.1 0.0043 16.7 14.4 3.7 1 1 1 2 2 2 2 Essential protein Yae1, N terminal HAP1_N PF04849.13 ORX94697.1 - 0.012 14.9 2.3 0.019 14.2 2.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF2312 PF10073.9 ORX94697.1 - 0.088 12.5 1.3 0.24 11.1 1.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) CRIM PF16978.5 ORX94698.1 - 1.9e-44 151.2 0.0 3.7e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 ORX94698.1 - 4.2e-18 65.6 0.7 1.1e-17 64.3 0.6 1.7 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RA PF00788.23 ORX94698.1 - 0.029 15.0 0.1 2.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Spermine_synth PF01564.17 ORX94699.1 - 1.8e-70 236.2 0.1 3.3e-70 235.3 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORX94699.1 - 2e-23 82.0 0.1 3.4e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ORX94699.1 - 1.6e-06 28.8 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX94699.1 - 2.9e-05 23.9 0.0 0.00015 21.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX94699.1 - 0.0025 18.5 0.0 0.0065 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 ORX94699.1 - 0.0048 16.2 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_11 PF08241.12 ORX94699.1 - 0.0056 17.3 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX94699.1 - 0.029 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 ORX94699.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 ORX94699.1 - 0.044 12.9 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_2 PF00891.18 ORX94699.1 - 0.12 11.7 0.3 0.21 10.8 0.2 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Gar1 PF04410.14 ORX94700.1 - 2.8e-30 105.1 0.0 4e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 ORX94701.1 - 9.6e-91 301.1 0.0 1.4e-44 151.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX94701.1 - 2.3e-27 94.5 1.2 6.8e-14 51.4 0.7 3.0 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORX94701.1 - 4.1e-15 55.9 0.0 3.2e-08 33.5 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX94701.1 - 1.2e-11 45.0 0.0 4.7e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORX94701.1 - 1.8e-11 44.2 0.1 7.3e-05 22.8 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX94701.1 - 4e-10 40.3 1.0 0.00037 20.9 0.1 4.1 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.13 ORX94701.1 - 6.5e-09 35.5 0.1 0.0031 16.8 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 ORX94701.1 - 4.3e-08 33.5 0.5 0.0039 17.5 0.1 4.2 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 ORX94701.1 - 2.3e-07 30.9 0.0 0.0004 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX94701.1 - 5e-07 30.0 0.0 0.0051 17.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.18 ORX94701.1 - 6.5e-07 29.4 0.0 2.7e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 ORX94701.1 - 3.7e-06 26.8 0.0 0.033 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORX94701.1 - 1.4e-05 24.6 0.4 0.078 12.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORX94701.1 - 2.7e-05 24.5 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 ORX94701.1 - 0.00014 21.8 0.0 0.014 15.3 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 ORX94701.1 - 0.00016 22.0 0.0 0.096 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORX94701.1 - 0.00019 21.0 0.0 0.16 11.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 ORX94701.1 - 0.00029 20.5 2.1 2.8 7.5 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ORX94701.1 - 0.00029 21.4 0.0 0.067 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ORX94701.1 - 0.00041 19.8 0.2 0.72 9.1 0.0 2.9 3 1 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 ORX94701.1 - 0.00058 19.6 0.0 0.19 11.4 0.0 3.7 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 ORX94701.1 - 0.00068 19.5 0.0 0.98 9.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 ORX94701.1 - 0.0011 19.0 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 ORX94701.1 - 0.0018 17.5 0.0 0.51 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 ORX94701.1 - 0.002 17.5 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 ORX94701.1 - 0.0025 18.4 0.0 0.13 12.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 ORX94701.1 - 0.0028 17.4 0.0 0.35 10.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 ORX94701.1 - 0.0035 17.3 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 ORX94701.1 - 0.0056 16.2 0.3 0.34 10.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.12 ORX94701.1 - 0.018 15.0 0.5 8.7 6.2 0.0 3.9 3 1 1 4 4 4 0 NACHT domain AAA_11 PF13086.6 ORX94701.1 - 0.018 14.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORX94701.1 - 0.019 14.1 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CDC48_2 PF02933.17 ORX94701.1 - 0.039 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Cytidylate_kin2 PF13189.6 ORX94701.1 - 0.048 13.8 0.0 4.4 7.4 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase-like family IPT PF01745.16 ORX94701.1 - 0.056 12.8 0.1 3 7.2 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 ORX94701.1 - 0.11 12.9 0.0 28 5.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 ORX94701.1 - 0.13 12.0 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORX94701.1 - 0.15 11.3 0.0 0.42 9.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 ORX94701.1 - 0.2 11.6 3.2 9.9 6.0 0.0 3.9 4 1 1 5 5 4 0 NTPase AAA_19 PF13245.6 ORX94701.1 - 0.3 11.4 0.8 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain Tau95 PF09734.9 ORX94702.1 - 3.8e-43 147.7 4.3 2.4e-42 145.1 1.7 2.4 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 ORX94702.1 - 3.2e-32 111.4 0.0 6.8e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain Complex1_49kDa PF00346.19 ORX94703.1 - 2.6e-122 407.1 0.0 3.2e-122 406.8 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 ORX94703.1 - 0.0026 16.8 0.0 0.005 15.8 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase TPR_1 PF00515.28 ORX94704.1 - 2.4e-21 74.6 3.7 4.4e-05 23.1 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORX94704.1 - 7.3e-18 63.2 5.5 0.00029 20.7 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX94704.1 - 3.8e-14 52.1 12.7 0.0021 17.7 0.7 5.3 3 2 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 ORX94704.1 - 2.5e-13 49.4 6.1 0.00013 22.1 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORX94704.1 - 2.5e-12 46.0 1.3 0.0049 17.0 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX94704.1 - 3.5e-12 46.1 9.1 0.019 15.7 0.7 6.3 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORX94704.1 - 2e-11 44.2 6.0 3.5e-05 24.2 0.2 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 ORX94704.1 - 8.2e-10 38.9 1.5 0.0019 18.5 0.0 4.0 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX94704.1 - 2.3e-08 34.5 5.8 0.0004 21.0 0.1 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORX94704.1 - 2.8e-08 33.2 0.4 0.017 15.1 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX94704.1 - 4.5e-08 33.3 3.3 0.034 14.4 1.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX94704.1 - 6.1e-06 26.4 2.5 5.3e-05 23.4 1.1 2.5 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORX94704.1 - 2e-05 24.6 4.1 0.058 13.5 0.2 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX94704.1 - 0.00048 20.6 1.4 4.4 8.2 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF1641 PF07849.11 ORX94704.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) TPR_4 PF07721.14 ORX94704.1 - 0.0086 16.6 0.1 0.041 14.5 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORX94704.1 - 0.037 13.9 11.6 0.36 10.8 1.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 ORX94704.1 - 0.071 12.1 0.5 8.4 5.3 0.0 2.1 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DHHC PF01529.20 ORX94705.1 - 4.3e-39 133.7 10.4 4.3e-39 133.7 10.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Myosin_head PF00063.21 ORX94706.1 - 3e-242 805.7 3.5 3.6e-242 805.4 3.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 ORX94706.1 - 2.5e-44 151.2 0.1 9.1e-44 149.4 0.0 1.9 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 ORX94706.1 - 1.8e-14 53.0 1.1 4.5e-14 51.8 1.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX94706.1 - 8.6e-13 47.9 0.0 8.5e-11 41.6 0.1 2.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORX94706.1 - 2.1e-09 36.9 0.5 8.2e-09 35.0 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 ORX94706.1 - 3.4e-05 24.0 0.1 9.9e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.12 ORX94706.1 - 0.014 14.9 0.1 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.27 ORX94706.1 - 0.018 14.8 5.5 0.43 10.5 0.8 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 ORX94706.1 - 0.024 15.0 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX94706.1 - 0.038 14.3 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORX94706.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 ORX94706.1 - 0.18 12.3 0.0 0.56 10.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 ORX94706.1 - 0.19 11.6 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Daxx PF03344.15 ORX94706.1 - 0.29 11.2 2.4 1.6 8.9 0.1 3.0 3 0 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain Peptidase_S9_N PF02897.15 ORX94707.1 - 6.8e-120 400.6 1.3 9.1e-120 400.2 1.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORX94707.1 - 6e-66 221.9 0.0 1.3e-65 220.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_C25_C PF03785.14 ORX94707.1 - 0.021 14.7 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Peptidase_S9_N PF02897.15 ORX94708.1 - 3.6e-124 414.7 0.9 4.6e-124 414.4 0.9 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORX94708.1 - 2.3e-55 187.4 0.7 8.6e-53 178.9 0.7 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_C25_C PF03785.14 ORX94708.1 - 0.055 13.3 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Ribonuc_red_lgC PF02867.15 ORX94709.1 - 1.5e-191 637.5 0.0 1.9e-191 637.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ORX94709.1 - 5.3e-25 87.2 0.1 1.8e-24 85.5 0.1 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ORX94709.1 - 2.9e-17 63.0 0.2 8.2e-17 61.6 0.2 1.8 1 0 0 1 1 1 1 ATP cone domain Zip PF02535.22 ORX94710.1 - 1.6e-55 188.6 12.0 3.9e-53 180.8 12.0 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter SART-1 PF03343.13 ORX94711.1 - 5.9e-147 490.9 53.9 6.9e-147 490.7 53.9 1.0 1 0 0 1 1 1 1 SART-1 family Cas_Cmr5 PF09701.10 ORX94711.1 - 0.016 15.5 0.0 0.016 15.5 0.0 3.1 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_Cmr5) L31 PF09784.9 ORX94712.1 - 1.5e-31 108.8 0.3 1.7e-31 108.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 AAA_PrkA PF08298.11 ORX94712.1 - 0.053 12.4 0.0 0.063 12.2 0.0 1.0 1 0 0 1 1 1 0 PrkA AAA domain Excalibur PF05901.11 ORX94712.1 - 0.21 12.3 0.4 1.2 9.9 0.0 2.4 2 1 1 3 3 3 0 Excalibur calcium-binding domain Ribosomal_60s PF00428.19 ORX94713.1 - 9.7e-28 96.6 13.2 1.1e-27 96.4 13.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein AMP-binding PF00501.28 ORX94727.1 - 0 1221.4 0.0 1.4e-90 304.0 0.0 7.3 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 ORX94727.1 - 2e-258 857.5 0.2 2.8e-59 201.0 0.0 10.2 7 2 3 10 10 10 10 Condensation domain PP-binding PF00550.25 ORX94727.1 - 4.4e-58 193.5 0.5 7.7e-14 51.8 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX94727.1 - 1.4e-17 64.4 1.9 0.012 16.6 0.0 5.0 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain DUF1378 PF07125.11 ORX94727.1 - 2.7e-05 24.2 0.1 8.8 6.6 0.0 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF1378) SUFU PF05076.13 ORX94727.1 - 4.5e-05 23.5 4.6 1.4 8.8 0.1 3.5 3 0 0 3 3 3 3 Suppressor of fused protein (SUFU) Glycoprot_B_PH2 PF17417.2 ORX94727.1 - 0.00032 21.0 0.2 20 5.6 0.0 3.9 3 0 0 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain DUF2109 PF09882.9 ORX94727.1 - 0.02 14.9 1.9 52 3.9 0.1 3.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) HTH_5 PF01022.20 ORX94727.1 - 0.28 11.1 2.7 92 3.0 0.1 3.7 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family DUF5122 PF17164.4 ORX94727.1 - 0.95 9.8 2.6 3e+02 1.8 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller PPR_3 PF13812.6 ORX94728.1 - 3.7e-47 158.2 1.4 1.9e-13 50.3 0.0 6.9 4 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_2 PF13041.6 ORX94728.1 - 8e-44 147.6 0.7 8.1e-09 35.5 0.0 8.3 5 2 3 8 8 8 6 PPR repeat family PPR_long PF17177.4 ORX94728.1 - 5.1e-27 94.6 5.4 1.6e-07 30.9 0.0 4.5 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORX94728.1 - 5.8e-24 82.6 2.7 0.023 14.9 0.0 9.8 9 0 0 9 9 9 5 PPR repeat PPR_1 PF12854.7 ORX94728.1 - 6.9e-14 51.3 3.1 2.1 8.1 0.0 8.7 9 0 0 9 9 9 5 PPR repeat ECSIT PF06239.11 ORX94728.1 - 0.0016 17.6 0.1 2.6 7.1 0.0 3.8 2 2 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.7 ORX94728.1 - 0.0042 16.9 0.5 5.4 6.9 0.0 3.9 4 1 0 4 4 4 1 Mitochondrial ATPase expression ERAP1_C PF11838.8 ORX94728.1 - 0.013 15.0 0.1 0.074 12.6 0.1 2.2 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Tudor-knot PF11717.8 ORX94728.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain BKACE PF05853.12 ORX94728.1 - 0.14 11.5 0.0 0.64 9.3 0.0 2.2 2 1 1 3 3 3 0 beta-keto acid cleavage enzyme DSPc PF00782.20 ORX94728.1 - 0.27 11.1 1.3 20 5.0 0.0 3.9 6 0 0 6 6 6 0 Dual specificity phosphatase, catalytic domain DUF676 PF05057.14 ORX94729.1 - 1.4e-07 31.3 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORX94729.1 - 0.00047 20.0 0.0 0.0023 17.7 0.0 2.3 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORX94729.1 - 0.00064 20.4 0.0 0.0012 19.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORX94729.1 - 0.0055 16.1 0.0 2.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 ORX94729.1 - 0.0085 16.2 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 ORX94729.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 ORX94729.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX94729.1 - 0.034 13.4 0.0 0.083 12.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 ORX94729.1 - 0.042 13.3 0.0 0.46 9.9 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.25 ORX94730.1 - 1.9e-74 250.4 0.0 2.5e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94730.1 - 2.1e-36 125.5 0.0 2.8e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORX94730.1 - 6e-11 42.9 3.5 1.4e-10 41.7 3.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORX94730.1 - 5.5e-06 25.6 0.0 8.2e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX94730.1 - 8.5e-06 25.3 0.0 1.8e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 ORX94730.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain APH PF01636.23 ORX94730.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX94730.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX94730.1 - 0.041 13.5 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Proteasom_Rpn13 PF04683.13 ORX94730.1 - 0.1 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Choline_kinase PF01633.20 ORX94730.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_transf_49 PF13896.6 ORX94731.1 - 2.9e-61 207.7 1.3 5e-50 170.7 1.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan NMT1 PF09084.11 ORX94732.1 - 1e-72 244.6 0.0 1.2e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ORX94732.1 - 8.6e-05 22.3 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 NMT1-like family PBP_like PF12727.7 ORX94732.1 - 0.087 11.9 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 PBP superfamily domain Phosphonate-bd PF12974.7 ORX94732.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein SUR7 PF06687.12 ORX94733.1 - 0.00034 20.3 1.6 0.00039 20.1 1.1 1.4 1 1 0 1 1 1 1 SUR7/PalI family Tetraspanin PF00335.20 ORX94733.1 - 0.00035 20.4 4.3 0.00035 20.4 4.3 1.3 1 1 0 1 1 1 1 Tetraspanin family Jagunal PF07086.12 ORX94733.1 - 0.025 14.7 1.2 0.036 14.1 0.6 1.4 1 1 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis DUF2981 PF11200.8 ORX94733.1 - 0.11 12.3 0.3 0.13 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) FKBP_C PF00254.28 ORX94734.1 - 6.1e-23 81.0 0.0 8.7e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MFS_1 PF07690.16 ORX94736.1 - 1.2e-25 90.3 38.7 1.2e-25 90.3 38.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_21 PF13506.6 ORX94736.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2070 PF09843.9 ORX94736.1 - 0.23 9.7 24.7 0.35 9.1 13.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF2417 PF10329.9 ORX94736.1 - 0.75 9.2 15.8 2.9 7.2 2.5 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF1394 PF07159.12 ORX94737.1 - 5.1e-109 364.2 3.1 5.8e-109 364.0 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) TetR_C_5 PF08360.11 ORX94737.1 - 0.035 14.3 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 QacR-like protein, C-terminal region CARD PF00619.21 ORX94737.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Caspase recruitment domain UPF0176_N PF17773.1 ORX94738.1 - 1e-23 83.5 0.0 2.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 ORX94738.1 - 1e-16 61.1 6.9 1.9e-16 60.1 6.9 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 ORX94738.1 - 1.2e-05 25.8 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain TRAPPC10 PF12584.8 ORX94739.1 - 4.7e-15 55.6 0.0 9.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 ORX94739.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking LRR_6 PF13516.6 ORX94740.1 - 1.5e-16 59.0 11.9 0.11 12.7 0.0 10.8 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 ORX94740.1 - 2.9e-15 56.1 5.6 0.023 15.1 0.0 7.3 4 3 2 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORX94740.1 - 9.3e-12 44.7 4.1 9.3e-12 44.7 4.1 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORX94740.1 - 7.5e-05 22.5 11.4 9.1e-05 22.2 4.6 3.1 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORX94740.1 - 0.6 10.9 17.4 14 6.7 0.0 7.7 8 0 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 ORX94740.1 - 3.8 7.8 7.1 37 4.7 0.1 3.9 2 2 1 4 4 4 0 Ste50p, sterile alpha motif RRM_1 PF00076.22 ORX94741.1 - 1.9e-31 107.7 0.1 5.3e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX94741.1 - 0.00014 21.8 0.2 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Presenilin PF01080.17 ORX94741.1 - 0.13 11.0 21.4 0.26 10.0 21.4 1.5 1 0 0 1 1 1 0 Presenilin Mitofilin PF09731.9 ORX94741.1 - 0.38 9.5 26.8 0.49 9.2 26.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nop14 PF04147.12 ORX94741.1 - 0.52 8.5 39.3 0.96 7.6 39.3 1.3 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 ORX94741.1 - 0.88 8.2 10.9 1.2 7.8 10.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Astro_capsid_p PF12226.8 ORX94741.1 - 3 6.9 21.7 4.8 6.2 21.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2151 PF10221.9 ORX94741.1 - 3.9 5.9 23.2 6 5.3 23.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Raftlin PF15250.6 ORX94741.1 - 6.7 5.3 19.9 12 4.4 19.9 1.4 1 0 0 1 1 1 0 Raftlin PI3K_1B_p101 PF10486.9 ORX94741.1 - 7 4.3 15.0 8.3 4.0 15.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM60A PF15396.6 ORX94741.1 - 7.1 6.6 27.7 2.4 8.1 24.7 1.7 2 0 0 2 2 2 0 Protein Family FAM60A Smg8_Smg9 PF10220.9 ORX94741.1 - 7.2 4.8 19.3 11 4.2 19.3 1.2 1 0 0 1 1 1 0 Smg8_Smg9 SLC12 PF03522.15 ORX94741.1 - 7.5 5.5 21.5 18 4.2 21.5 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Nfu_N PF08712.11 ORX94742.1 - 3.1e-29 100.8 0.0 8.4e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORX94742.1 - 1.3e-28 98.9 0.1 2.2e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain His_Phos_1 PF00300.22 ORX94743.1 - 9e-18 64.7 0.0 3.2e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ORX94743.1 - 0.0049 16.3 0.1 0.021 14.2 0.1 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) adh_short_C2 PF13561.6 ORX94744.1 - 1.6e-61 207.9 0.0 2.1e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX94744.1 - 2.8e-51 173.8 0.4 3.7e-51 173.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX94744.1 - 1.4e-13 51.2 0.1 2e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORX94744.1 - 1.5e-06 27.9 0.8 1.3e-05 24.8 0.2 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX94744.1 - 3.4e-05 23.4 0.2 0.00075 19.0 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORX94744.1 - 0.0011 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORX94744.1 - 0.0027 16.9 0.1 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ELFV_dehydrog PF00208.21 ORX94744.1 - 0.0094 15.7 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DFP PF04127.15 ORX94744.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Sugar_tr PF00083.24 ORX94761.1 - 2e-101 340.1 27.8 2.4e-101 339.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94761.1 - 1.8e-28 99.5 27.4 1.8e-28 99.5 27.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 ORX94761.1 - 0.0013 17.6 3.0 0.0066 15.2 3.2 1.8 1 1 1 2 2 2 1 Reduced folate carrier FAD_binding_4 PF01565.23 ORX94762.1 - 1e-21 77.1 0.4 2.4e-21 75.9 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX94762.1 - 8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.24 ORX94763.1 - 3e-101 339.5 28.1 3.5e-101 339.3 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94763.1 - 2.2e-28 99.2 27.3 2.2e-28 99.2 27.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 ORX94763.1 - 0.0013 17.6 3.0 0.0066 15.2 3.2 1.8 1 1 1 2 2 2 1 Reduced folate carrier WRKY PF03106.15 ORX94764.1 - 5.8e-08 32.9 3.1 1.3e-07 31.7 3.1 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Sugar_tr PF00083.24 ORX94765.1 - 2e-101 340.1 27.8 2.4e-101 339.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94765.1 - 1.8e-28 99.5 27.4 1.8e-28 99.5 27.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 ORX94765.1 - 0.0013 17.6 3.0 0.0066 15.2 3.2 1.8 1 1 1 2 2 2 1 Reduced folate carrier GPI-anchored PF10342.9 ORX94766.1 - 0.062 14.1 0.0 0.087 13.6 0.0 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_61 PF03443.14 ORX94767.1 - 0.001 19.0 0.9 0.0014 18.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX94767.1 - 0.046 14.4 5.6 0.082 13.6 5.6 1.5 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading RRM_1 PF00076.22 ORX94768.1 - 7.4e-36 121.8 0.6 7e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX94768.1 - 7.9e-06 25.9 0.1 0.0006 19.9 0.0 3.1 2 2 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 ORX94768.1 - 0.0011 18.7 0.1 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain OB_RNB PF08206.11 ORX94768.1 - 0.088 12.5 0.7 0.96 9.2 0.2 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain RGS PF00615.19 ORX94769.1 - 7.3e-14 52.1 2.7 1.2e-13 51.3 2.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX94770.1 - 2.7e-09 37.3 2.7 4.5e-09 36.6 2.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX94771.1 - 6.3e-14 52.2 2.7 1.1e-13 51.5 2.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX94772.1 - 4.2e-14 52.8 2.3 6.9e-14 52.1 2.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX94773.1 - 6.6e-14 52.2 2.7 1.1e-13 51.5 2.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORX94774.1 - 6.6e-14 52.2 2.7 1.1e-13 51.5 2.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1963 PF09234.10 ORX94775.1 - 2.4e-12 47.8 0.0 3.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) YkyA PF10368.9 ORX94776.1 - 0.19 11.4 7.8 0.33 10.6 7.8 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Sec20 PF03908.13 ORX94776.1 - 0.21 11.6 1.5 1.3 9.0 0.2 2.4 1 1 1 2 2 2 0 Sec20 Vac_ImportDeg PF09783.9 ORX94777.1 - 7.7e-45 152.6 0.1 1e-44 152.2 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF572 PF04502.13 ORX94777.1 - 0.19 11.3 4.5 0.24 11.0 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pes-10 PF07149.11 ORX94777.1 - 0.53 9.3 11.2 0.72 8.8 11.2 1.1 1 0 0 1 1 1 0 Pes-10 UPF0139 PF03669.13 ORX94778.1 - 3.6e-21 74.8 0.0 4.3e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) MG2 PF01835.19 ORX94779.1 - 0.0007 20.0 0.0 0.0016 18.9 0.0 1.6 1 1 0 1 1 1 1 MG2 domain NAR2 PF16974.5 ORX94779.1 - 0.076 12.4 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory DUF4625 PF15418.6 ORX94779.1 - 0.095 12.9 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) Ndufs5 PF10200.9 ORX94780.1 - 0.0024 18.1 0.7 0.0035 17.6 0.7 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 ORX94780.1 - 0.0096 16.1 0.9 0.015 15.5 0.9 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Exotox-A_target PF09102.10 ORX94780.1 - 0.099 12.6 0.6 0.11 12.5 0.3 1.3 1 1 0 1 1 1 0 Exotoxin A, targeting DUF3128 PF11326.8 ORX94780.1 - 0.25 11.8 4.6 1.1 9.6 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 ORX94780.1 - 0.86 9.9 5.0 1.7 8.9 0.1 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Ribosomal_L32e PF01655.18 ORX94781.1 - 1.3e-53 180.0 3.0 1.9e-53 179.5 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 AAA PF00004.29 ORX94782.1 - 4.2e-44 150.2 0.0 1.1e-43 148.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX94782.1 - 1.2e-11 44.2 0.0 3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORX94782.1 - 7.6e-08 32.7 0.1 3.5e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 ORX94782.1 - 7.9e-08 32.1 0.6 1.9e-07 30.9 0.6 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORX94782.1 - 3.3e-07 30.4 0.0 1.4e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX94782.1 - 3e-06 27.7 0.0 7.5e-05 23.2 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORX94782.1 - 3.2e-05 24.2 0.7 0.0063 16.8 0.2 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ORX94782.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORX94782.1 - 0.00088 18.6 0.0 0.0021 17.3 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORX94782.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORX94782.1 - 0.0017 18.9 0.1 0.021 15.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 ORX94782.1 - 0.0024 17.8 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ORX94782.1 - 0.0024 17.7 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORX94782.1 - 0.0065 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 ORX94782.1 - 0.0082 15.6 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 ORX94782.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORX94782.1 - 0.012 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2072 PF09845.9 ORX94782.1 - 0.014 15.7 0.2 0.032 14.5 0.2 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein ATPase PF06745.13 ORX94782.1 - 0.015 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 ORX94782.1 - 0.021 14.6 0.0 0.092 12.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORX94782.1 - 0.024 14.4 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX94782.1 - 0.026 14.9 0.1 0.4 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 ORX94782.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORX94782.1 - 0.029 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 ORX94782.1 - 0.034 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORX94782.1 - 0.037 14.4 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HR1 PF02185.16 ORX94782.1 - 0.051 13.7 1.9 0.17 12.0 1.9 1.9 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 ORX94782.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORX94782.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ORX94782.1 - 0.071 13.5 0.1 0.35 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORX94782.1 - 0.081 12.7 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORX94782.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.27 ORX94783.1 - 3.5e-46 157.2 0.0 5.6e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORX94783.1 - 3.5e-15 56.3 0.0 1.2e-13 51.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORX94783.1 - 1.2e-10 41.7 0.8 2.7e-09 37.3 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORX94783.1 - 2.2e-05 24.5 0.0 0.011 15.9 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORX94783.1 - 0.00017 21.5 0.3 0.0006 19.7 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 UPF0179 PF03684.13 ORX94784.1 - 0.038 13.9 0.0 0.098 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0179) OPT PF03169.15 ORX94785.1 - 2.5e-122 409.6 38.8 6.9e-121 404.8 38.8 2.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein RGS PF00615.19 ORX94792.1 - 5.6e-13 49.2 2.0 1.2e-12 48.2 2.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain SdpI PF13630.6 ORX94792.1 - 0.064 13.4 1.9 1.6 8.9 0.0 2.7 2 1 0 2 2 2 0 SdpI/YhfL protein family STE PF02200.16 ORX94793.1 - 0.021 15.3 0.6 0.053 14.0 0.6 1.7 1 1 0 1 1 1 0 STE like transcription factor DUF3326 PF11805.8 ORX94794.1 - 0.082 11.8 0.0 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3326) Bac_globin PF01152.21 ORX94797.1 - 5.3e-11 42.7 0.1 6.2e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX94797.1 - 0.0029 17.5 0.1 0.005 16.7 0.1 1.4 1 1 0 1 1 1 1 Protoglobin Ribosomal_L27e PF01777.18 ORX94797.1 - 0.021 15.2 0.5 0.031 14.6 0.5 1.4 1 1 0 1 1 1 0 Ribosomal L27e protein family CBM_2 PF00553.19 ORX94798.1 - 0.073 13.4 0.3 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 Cellulose binding domain DUF3201 PF11447.8 ORX94798.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) DUF4233 PF14017.6 ORX94799.1 - 0.025 14.9 1.0 0.025 14.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) PEMT PF04191.13 ORX94800.1 - 6.1e-34 116.6 3.1 6.1e-34 116.6 3.1 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase PRiA4_ORF3 PF07929.11 ORX94801.1 - 1.2e-09 38.1 0.2 6.6e-09 35.7 0.2 2.0 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Ald_Xan_dh_C2 PF02738.18 ORX94802.1 - 2e-195 650.4 0.0 2.8e-195 649.9 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORX94802.1 - 3.1e-50 170.2 0.0 6.7e-50 169.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 ORX94802.1 - 5.4e-35 120.1 0.2 1.2e-34 119.0 0.2 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 ORX94802.1 - 1.1e-30 105.9 0.0 6.4e-29 100.2 0.0 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 ORX94802.1 - 8.6e-30 102.6 0.0 1.9e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 ORX94802.1 - 1.2e-08 34.7 0.1 1.2e-08 34.7 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 ORX94802.1 - 0.093 12.8 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 DUF218 domain C2 PF00168.30 ORX94803.1 - 1.2e-27 96.2 0.0 1.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 C2 domain CHAP PF05257.16 ORX94804.1 - 4.4e-09 36.8 7.4 4.4e-09 36.8 7.4 1.6 1 1 0 1 1 1 1 CHAP domain Spt20 PF12090.8 ORX94805.1 - 9.3e-20 71.2 0.2 7.1e-12 45.4 0.0 4.3 2 2 1 3 3 3 2 Spt20 family RRM_1 PF00076.22 ORX94806.1 - 2.5e-17 62.4 0.0 3.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX94806.1 - 0.012 15.7 0.0 0.03 14.5 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 ORX94806.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HPPK PF01288.20 ORX94806.1 - 0.06 13.9 0.4 0.092 13.3 0.4 1.2 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Hep_59 PF07052.11 ORX94807.1 - 7.5e-31 107.0 2.0 7.5e-31 107.0 2.0 2.6 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 CN_hydrolase PF00795.22 ORX94808.1 - 4.6e-55 186.8 0.0 5.3e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L21p PF00829.21 ORX94809.1 - 2.1e-26 92.1 1.9 2.9e-26 91.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein F-box_4 PF15966.5 ORX94810.1 - 6.1e-05 22.9 0.5 0.00017 21.5 0.5 1.8 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORX94810.1 - 0.0068 16.3 2.2 0.017 15.0 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX94810.1 - 0.094 12.6 1.1 0.18 11.7 1.1 1.5 1 0 0 1 1 1 0 F-box-like Protocadherin PF08374.11 ORX94810.1 - 0.21 11.5 0.8 0.33 10.9 0.3 1.5 2 0 0 2 2 2 0 Protocadherin JmjC PF02373.22 ORX94811.1 - 1.2e-13 51.5 0.3 1.7e-12 47.8 0.1 2.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 ORX94811.1 - 7.5e-09 35.7 19.5 7.5e-09 35.7 19.5 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Myticin-prepro PF10690.9 ORX94828.1 - 0.046 14.0 0.3 0.046 14.0 0.3 2.0 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Zn_ribbon_2 PF12674.7 ORX94828.1 - 0.048 14.3 0.9 0.51 11.0 0.2 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain Pkinase PF00069.25 ORX94829.1 - 2.3e-21 76.3 0.0 5.9e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94829.1 - 7.5e-14 51.6 0.0 1.8e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_98M PF08306.11 ORX94830.1 - 0.043 13.1 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Sporozoite_P67 PF05642.11 ORX94830.1 - 0.12 10.5 9.0 0.13 10.3 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lipase_3 PF01764.25 ORX94831.1 - 2.6e-34 118.1 0.0 3.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX94831.1 - 0.0002 21.0 0.2 0.0034 17.0 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX94831.1 - 0.0012 19.5 0.0 0.0016 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ox_reductase_C PF08635.10 ORX94831.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain DUF2048 PF09752.9 ORX94831.1 - 0.041 13.0 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Hydrolase_4 PF12146.8 ORX94831.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORX94831.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family CHAP PF05257.16 ORX94832.1 - 8.1e-10 39.2 2.6 1.4e-09 38.4 2.6 1.4 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX94833.1 - 8.7e-10 39.1 2.4 1.5e-09 38.3 2.4 1.4 1 0 0 1 1 1 1 CHAP domain Amidohydro_1 PF01979.20 ORX94834.1 - 3.8e-08 33.0 0.0 4.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family CBM_5_12 PF02839.14 ORX94835.1 - 1.9e-05 25.0 11.9 1.9e-05 25.0 11.9 1.9 2 1 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX94835.1 - 0.0076 16.2 4.8 0.01 15.7 4.8 1.4 1 1 0 1 1 1 1 Cellulose-binding domain Glyco_hydro_18 PF00704.28 ORX94836.1 - 2.9e-53 181.6 0.0 3.4e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_61 PF03443.14 ORX94837.1 - 0.0013 18.7 0.1 0.08 12.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX94837.1 - 0.0015 19.2 0.6 0.0082 16.8 0.6 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Acetyltransf_1 PF00583.25 ORX94838.1 - 9.9e-07 29.0 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX94838.1 - 7.7e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX94838.1 - 0.00057 19.8 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX94838.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SKN1 PF03935.15 ORX94839.1 - 0.022 13.2 0.0 0.022 13.2 0.0 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) RGS PF00615.19 ORX94841.1 - 1.3e-14 54.4 0.1 2e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Glyco_hydro_57 PF03065.15 ORX94841.1 - 0.04 13.1 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 YobH PF13996.6 ORX94841.1 - 0.054 13.6 0.6 0.25 11.4 0.6 2.1 1 0 0 1 1 1 0 YobH-like protein SLC3A2_N PF16028.5 ORX94841.1 - 0.15 11.7 0.8 0.76 9.4 0.8 2.2 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus SH PF01445.17 ORX94841.1 - 0.49 10.4 4.9 6 6.9 0.2 3.0 2 0 0 2 2 2 0 Viral small hydrophobic protein GPI-anchored PF10342.9 ORX94842.1 - 2.5e-16 60.2 0.2 2.5e-16 60.2 0.2 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.17 ORX94842.1 - 0.0076 16.3 13.7 0.011 15.7 13.7 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SOG2 PF10428.9 ORX94842.1 - 0.057 12.6 14.9 0.061 12.5 14.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 ORX94842.1 - 0.9 9.4 7.1 0.93 9.3 7.1 1.1 1 0 0 1 1 1 0 SPX domain KAR9 PF08580.10 ORX94842.1 - 0.97 7.9 8.9 1 7.8 8.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Hamartin PF04388.12 ORX94842.1 - 1.4 7.5 13.0 1.7 7.2 13.0 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 ORX94842.1 - 8.8 5.0 9.9 11 4.7 9.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Opi1 PF08618.10 ORX94844.1 - 7e-78 262.7 6.4 3.8e-45 154.9 1.3 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 Perilipin PF03036.16 ORX94844.1 - 2.7e-14 53.0 0.2 9.4e-14 51.2 0.1 1.8 1 1 1 2 2 2 1 Perilipin family REF PF05755.12 ORX94844.1 - 8.8e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) CBM_19 PF03427.13 ORX94846.1 - 3.5e-12 46.1 35.9 0.00075 19.4 2.9 5.2 4 1 1 5 5 5 5 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX94846.1 - 1.6e-06 28.2 39.9 0.12 12.5 4.5 5.3 3 1 1 4 4 4 4 Chitin binding Peritrophin-A domain DUF1376 PF07120.11 ORX94846.1 - 0.0072 16.6 0.3 11 6.4 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1376) SCNM1_acidic PF15805.5 ORX94846.1 - 0.11 12.3 4.2 31 4.4 0.0 3.8 4 0 0 4 4 4 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DUF2793 PF10983.8 ORX94846.1 - 0.18 11.7 0.1 5 7.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2793) Kazal_3 PF18434.1 ORX94846.1 - 0.51 10.1 19.0 3 7.7 0.1 4.9 4 0 0 4 4 4 0 Kazal-type serine protease inhibitor domain CBM_19 PF03427.13 ORX94847.1 - 3.5e-12 46.1 35.9 0.00075 19.4 2.9 5.2 4 1 1 5 5 5 5 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX94847.1 - 1.6e-06 28.2 39.9 0.12 12.5 4.5 5.3 3 1 1 4 4 4 4 Chitin binding Peritrophin-A domain DUF1376 PF07120.11 ORX94847.1 - 0.0072 16.6 0.3 11 6.4 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1376) SCNM1_acidic PF15805.5 ORX94847.1 - 0.11 12.3 4.2 31 4.4 0.0 3.8 4 0 0 4 4 4 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DUF2793 PF10983.8 ORX94847.1 - 0.18 11.7 0.1 5 7.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2793) Kazal_3 PF18434.1 ORX94847.1 - 0.51 10.1 19.0 3 7.7 0.1 4.9 4 0 0 4 4 4 0 Kazal-type serine protease inhibitor domain Lactamase_B PF00753.27 ORX94855.1 - 1.2e-17 64.6 0.0 2.4e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX94855.1 - 4.1e-05 23.2 0.0 6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Con-6 PF10346.9 ORX94856.1 - 4.9e-16 58.5 8.2 1.4e-07 31.4 0.7 2.5 2 0 0 2 2 2 2 Conidiation protein 6 DUF3933 PF13069.6 ORX94856.1 - 0.041 13.7 0.3 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Xan_ur_permease PF00860.20 ORX94857.1 - 1.2e-62 211.9 30.8 3.4e-61 207.1 30.8 2.1 1 1 0 1 1 1 1 Permease family FAD_binding_4 PF01565.23 ORX94858.1 - 1.9e-26 92.5 2.6 4.1e-26 91.4 2.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX94858.1 - 1.5e-16 60.2 0.1 2.8e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like CAP PF00188.26 ORX94859.1 - 7.2e-18 65.6 0.0 9.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Kinesin PF00225.23 ORX94860.1 - 1.1e-102 343.5 0.1 1.1e-102 343.5 0.1 2.4 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORX94860.1 - 8.5e-57 191.3 0.0 2.5e-56 189.7 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Rho_Binding PF08912.11 ORX94860.1 - 0.022 15.5 8.9 0.022 15.5 8.9 5.2 2 1 3 5 5 5 0 Rho Binding Spc29 PF17082.5 ORX94860.1 - 0.1 12.5 19.8 0.16 11.8 6.8 2.9 1 1 1 2 2 2 0 Spindle Pole Component 29 CALCOCO1 PF07888.11 ORX94860.1 - 0.14 11.0 36.9 0.24 10.2 36.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 ORX94860.1 - 0.84 7.7 42.2 0.028 12.6 15.5 2.7 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil ERM PF00769.19 ORX94860.1 - 1.2 8.9 40.0 3 7.6 40.0 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PspA_IM30 PF04012.12 ORX94860.1 - 1.2 8.6 31.4 23 4.5 1.1 3.8 1 1 2 3 3 3 0 PspA/IM30 family UPF0242 PF06785.11 ORX94860.1 - 2.5 8.1 41.8 1.3 9.1 16.5 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 ORX94860.1 - 3.3 6.5 36.3 6.2 5.6 13.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Sipho_Gp157 PF05565.11 ORX94860.1 - 4 7.4 27.8 0.028 14.4 15.8 2.4 1 1 1 2 2 2 0 Siphovirus Gp157 XhlA PF10779.9 ORX94860.1 - 5.9 7.2 22.3 1.1 9.5 1.1 4.0 3 1 1 4 4 4 0 Haemolysin XhlA Ribosom_S12_S23 PF00164.25 ORX94861.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S21e PF01249.18 ORX94862.1 - 4.2e-40 135.7 0.0 4.7e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4325 PF14213.6 ORX94862.1 - 0.065 12.9 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) eIF3_subunit PF08597.10 ORX94863.1 - 7.4e-58 196.3 26.9 8.3e-58 196.2 26.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Baculo_PEP_C PF04513.12 ORX94863.1 - 0.005 16.9 0.1 0.0073 16.3 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4604 PF15377.6 ORX94863.1 - 4.1 7.8 27.9 16 5.9 27.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) SBDS PF01172.18 ORX94864.1 - 1.5e-20 73.0 0.2 2e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF842 PF05811.13 ORX94865.1 - 0.0034 17.1 0.4 0.025 14.3 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF842) TMEM65 PF10507.9 ORX94865.1 - 0.12 12.4 0.0 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 65 PAN_3 PF08277.12 ORX94865.1 - 5.6 6.8 10.3 1.5 8.7 0.9 3.1 3 0 0 3 3 3 0 PAN-like domain Cyclin_N PF00134.23 ORX94866.1 - 1.1e-16 60.7 3.6 1.2e-15 57.3 0.5 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX94866.1 - 5.6e-05 23.2 0.7 0.022 14.9 0.2 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 ORX94866.1 - 0.00014 22.2 0.8 0.00048 20.5 0.2 2.3 2 1 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 ORX94866.1 - 0.00021 21.2 0.1 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Ribosomal_60s PF00428.19 ORX94867.1 - 5.6e-27 94.2 12.5 6.6e-27 93.9 12.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cyt-b5 PF00173.28 ORX94868.1 - 7.4e-10 38.8 0.1 1e-09 38.4 0.1 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HAD_2 PF13419.6 ORX94869.1 - 1.7e-26 93.4 0.0 2.2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX94869.1 - 4.8e-17 63.0 0.1 2.1e-13 51.1 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX94869.1 - 1.4e-07 31.5 0.0 4.4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORX94869.1 - 0.0014 19.0 0.1 0.0034 17.8 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Con-6 PF10346.9 ORX94870.1 - 8.2e-16 57.7 8.0 1.2e-07 31.6 0.9 2.4 2 0 0 2 2 2 2 Conidiation protein 6 Con-6 PF10346.9 ORX94871.1 - 1.6e-16 60.0 7.9 8e-08 32.2 1.3 2.4 2 0 0 2 2 2 2 Conidiation protein 6 DUF3933 PF13069.6 ORX94871.1 - 0.015 15.1 0.3 5 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) DotD PF16816.5 ORX94871.1 - 0.073 13.0 1.6 8.2 6.4 0.0 2.1 2 0 0 2 2 2 0 DotD protein Con-6 PF10346.9 ORX94872.1 - 1.3e-16 60.3 9.4 7e-08 32.4 1.3 2.4 2 0 0 2 2 2 2 Conidiation protein 6 DUF3933 PF13069.6 ORX94872.1 - 0.014 15.2 0.6 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Con-6 PF10346.9 ORX94873.1 - 5.3e-08 32.8 0.9 1e-07 31.8 0.9 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Glyco_hydro_32N PF00251.20 ORX94874.1 - 1.3e-63 215.4 3.7 2.5e-63 214.5 3.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORX94874.1 - 4e-31 108.1 0.1 6.2e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 ORX94874.1 - 0.0006 19.9 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR_2 PF13088.6 ORX94874.1 - 0.0062 15.9 0.1 0.025 13.9 0.1 2.0 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 ORX94874.1 - 0.032 14.2 0.9 0.19 11.8 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat HAD_2 PF13419.6 ORX94875.1 - 1.7e-26 93.4 0.0 2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX94875.1 - 6.1e-17 62.6 0.1 2.1e-13 51.0 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX94875.1 - 3.9e-07 30.0 0.0 1.2e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORX94875.1 - 0.0013 19.2 0.1 0.0034 17.8 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Con-6 PF10346.9 ORX94876.1 - 2.3e-16 59.5 8.1 1.2e-07 31.7 0.8 2.4 2 0 0 2 2 2 2 Conidiation protein 6 DUF3519 PF12033.8 ORX94876.1 - 0.08 13.4 3.2 4 7.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) DotD PF16816.5 ORX94876.1 - 0.096 12.6 2.7 3.3 7.7 0.1 2.1 2 0 0 2 2 2 0 DotD protein DUF3933 PF13069.6 ORX94876.1 - 0.16 11.9 0.3 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Con-6 PF10346.9 ORX94877.1 - 5.6e-17 61.5 7.8 4.2e-08 33.1 0.7 2.3 2 0 0 2 2 2 2 Conidiation protein 6 Phage_lysozyme PF00959.19 ORX94878.1 - 7.8e-15 55.3 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.11 ORX94878.1 - 3.9e-08 33.4 1.3 7.2e-08 32.6 1.3 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Trypsin PF00089.26 ORX94890.1 - 5.3e-29 101.6 0.0 7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX94890.1 - 0.0021 19.0 0.0 0.0028 18.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain HSP70 PF00012.20 ORX94891.1 - 2.7e-263 874.6 6.4 3.1e-263 874.4 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX94891.1 - 3.3e-16 59.0 0.1 5.6e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX94891.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX94891.1 - 0.0086 15.4 0.1 0.02 14.2 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX94891.1 - 0.017 14.6 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX94891.1 - 0.025 14.8 4.7 0.26 11.5 0.6 2.5 2 1 0 2 2 2 0 MutS domain III DDR PF08841.10 ORX94891.1 - 0.086 11.8 0.3 0.72 8.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF3849 PF12960.7 ORX94891.1 - 0.11 12.5 0.4 0.23 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) StbA PF06406.11 ORX94891.1 - 0.15 11.3 0.7 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 StbA protein Golgin_A5 PF09787.9 ORX94891.1 - 4.5 6.6 9.0 1.9 7.9 5.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Nefa_Nip30_N PF10187.9 ORX94891.1 - 4.9 7.6 9.2 12 6.3 9.2 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Atg14 PF10186.9 ORX94891.1 - 10 5.1 10.0 1.5 7.8 5.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HSP70 PF00012.20 ORX94892.1 - 1.8e-262 871.9 5.6 2.1e-262 871.7 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX94892.1 - 6.7e-16 58.0 0.0 1.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX94892.1 - 0.0048 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX94892.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX94892.1 - 0.017 14.6 0.0 4.6 6.6 0.1 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX94892.1 - 0.037 14.3 5.6 0.38 10.9 1.1 2.5 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX94892.1 - 0.11 12.5 0.4 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) StbA PF06406.11 ORX94892.1 - 0.13 11.4 0.5 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 StbA protein Golgin_A5 PF09787.9 ORX94892.1 - 4.6 6.6 9.0 1.9 7.9 5.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Nefa_Nip30_N PF10187.9 ORX94892.1 - 5 7.5 9.2 12 6.3 9.2 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 HSP70 PF00012.20 ORX94893.1 - 1.5e-286 951.4 10.0 4.4e-201 669.2 0.9 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ORX94893.1 - 4.1e-16 58.7 0.1 6.6e-15 54.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX94893.1 - 0.00058 19.7 0.0 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX94893.1 - 0.0095 15.2 0.1 0.023 13.9 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX94893.1 - 0.02 14.4 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1843 PF08898.10 ORX94893.1 - 0.035 14.6 4.8 5.1 7.7 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) MutS_III PF05192.18 ORX94893.1 - 0.045 14.0 4.9 0.35 11.1 0.9 2.5 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX94893.1 - 0.12 12.4 0.4 0.26 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) StbA PF06406.11 ORX94893.1 - 0.15 11.2 0.6 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 StbA protein Golgin_A5 PF09787.9 ORX94893.1 - 5.5 6.4 9.0 2.1 7.7 5.3 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 Nefa_Nip30_N PF10187.9 ORX94893.1 - 5.6 7.4 9.2 14 6.1 9.2 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 GPI-anchored PF10342.9 ORX94894.1 - 0.00013 22.6 0.2 0.00023 21.8 0.0 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HSP70 PF00012.20 ORX94895.1 - 2.7e-263 874.6 6.5 3e-263 874.5 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX94895.1 - 3.1e-16 59.1 0.1 5.5e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX94895.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX94895.1 - 0.0085 15.4 0.1 0.02 14.2 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX94895.1 - 0.017 14.7 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX94895.1 - 0.041 14.1 5.2 0.3 11.3 0.9 2.5 2 1 0 2 2 2 0 MutS domain III DDR PF08841.10 ORX94895.1 - 0.085 11.8 0.3 0.71 8.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF3849 PF12960.7 ORX94895.1 - 0.11 12.5 0.4 0.23 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) StbA PF06406.11 ORX94895.1 - 0.14 11.3 0.7 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 StbA protein Golgin_A5 PF09787.9 ORX94895.1 - 4.4 6.7 9.0 1.8 7.9 5.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 Nefa_Nip30_N PF10187.9 ORX94895.1 - 4.8 7.6 9.2 12 6.3 9.2 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Atg14 PF10186.9 ORX94895.1 - 9.8 5.2 10.0 1.5 7.8 5.3 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2 PF00096.26 ORX94896.1 - 3.2e-08 33.6 9.5 0.0005 20.4 2.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX94896.1 - 0.00073 20.2 7.0 0.56 11.2 1.4 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORX94896.1 - 0.0021 18.6 0.6 1.3 9.7 0.1 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORX94896.1 - 0.0024 18.2 0.8 0.0024 18.2 0.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORX94896.1 - 0.046 14.0 5.6 0.91 9.9 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc ribbon Ribosomal_L35p PF01632.19 ORX94896.1 - 0.15 12.6 2.4 0.38 11.3 2.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L35 NIF PF03031.18 ORX94897.1 - 1.5e-24 86.5 0.5 2.1e-24 86.1 0.5 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mt_ATP-synt_B PF05405.14 ORX94898.1 - 8.6e-49 165.3 7.2 1.2e-48 164.9 7.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SapB_1 PF05184.15 ORX94898.1 - 0.098 12.7 0.8 0.75 9.9 0.0 2.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 Fib_alpha PF08702.10 ORX94898.1 - 0.39 10.9 6.2 0.92 9.7 6.2 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family C2 PF00168.30 ORX94899.1 - 2e-25 89.1 0.0 2.3e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF4497 PF14924.6 ORX94899.1 - 0.01 16.3 0.0 1.1 9.7 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4497) Glyco_hydro_46 PF01374.18 ORX94900.1 - 2.8e-26 92.5 0.0 3.1e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Allantoicase PF03561.15 ORX94901.1 - 3.5e-92 305.9 0.0 4.8e-48 162.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat MMR_HSR1 PF01926.23 ORX94902.1 - 8.2e-21 74.2 0.0 1.6e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX94902.1 - 1.6e-12 47.2 0.0 2.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORX94902.1 - 3.9e-09 36.8 0.3 1.8e-06 28.1 0.1 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORX94902.1 - 7.5e-08 32.5 0.2 0.011 15.7 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase KH_2 PF07650.17 ORX94902.1 - 3.8e-07 29.9 0.2 1.2e-06 28.3 0.2 1.9 1 0 0 1 1 1 1 KH domain GTP_EFTU PF00009.27 ORX94902.1 - 3.5e-06 26.7 0.1 0.0014 18.2 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORX94902.1 - 5.4e-06 25.9 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Arf PF00025.21 ORX94902.1 - 0.00028 20.4 0.0 0.0015 18.0 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 ORX94902.1 - 0.0083 15.9 0.2 0.63 9.8 0.0 2.2 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 ORX94902.1 - 0.042 13.2 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 ORX94902.1 - 0.049 13.2 0.2 1.8 8.1 0.0 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 ORX94902.1 - 0.06 12.5 0.0 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Ras PF00071.22 ORX94902.1 - 0.078 12.6 0.0 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Ras family ABC_tran PF00005.27 ORX94902.1 - 0.15 12.6 0.1 0.34 11.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Cyclin PF08613.11 ORX94903.1 - 2e-35 122.5 0.4 3.8e-35 121.7 0.3 1.3 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX94903.1 - 9.8e-08 31.8 0.8 1.9e-07 30.9 0.6 1.6 1 1 1 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.26 ORX94904.1 - 5.6e-17 61.7 0.0 5.9e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX94904.1 - 0.0037 17.5 0.0 0.0042 17.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain GSH_synth_ATP PF03917.17 ORX94905.1 - 1.5e-140 468.3 0.0 1.7e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ORX94905.1 - 7.3e-38 129.2 0.0 1.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Vps5 PF09325.10 ORX94906.1 - 3.2e-22 79.2 8.5 5.7e-22 78.4 8.5 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORX94906.1 - 1.1e-15 57.6 1.3 2.3e-15 56.6 0.3 2.0 3 0 0 3 3 3 1 PX domain DUF962 PF06127.11 ORX94907.1 - 1.7e-18 66.5 1.6 3.8e-18 65.4 1.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Ribosomal_S24e PF01282.19 ORX94908.1 - 1.6e-38 130.5 1.3 1.8e-38 130.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e ING PF12998.7 ORX94910.1 - 3e-05 24.5 0.3 7.6e-05 23.2 0.3 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORX94910.1 - 0.0037 17.1 2.9 0.0071 16.2 2.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORX94910.1 - 0.0044 17.3 0.5 0.009 16.2 0.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain NusB PF01029.18 ORX94910.1 - 0.018 15.3 1.0 0.037 14.3 1.0 1.6 1 0 0 1 1 1 0 NusB family zf-HC5HC2H_2 PF13832.6 ORX94910.1 - 0.026 14.7 0.4 0.049 13.8 0.4 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain SRP-alpha_N PF04086.13 ORX94910.1 - 0.029 14.3 9.6 0.035 14.0 9.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 ORX94910.1 - 3.2 6.4 8.1 3.4 6.3 8.1 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 ORX94910.1 - 4.5 6.4 4.8 5 6.3 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 ORX94910.1 - 8 4.6 12.2 9.4 4.4 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S3_C PF00189.20 ORX94911.1 - 1e-23 83.7 1.1 3.9e-23 81.8 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORX94911.1 - 1.2e-12 47.4 0.1 2.2e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORX94911.1 - 0.047 14.2 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 ORX94911.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus HEAT PF02985.22 ORX94912.1 - 9.3e-48 156.1 22.0 0.00011 22.2 0.1 14.7 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 ORX94912.1 - 9.3e-43 144.5 3.6 3.9e-11 43.2 0.0 7.9 2 2 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 ORX94912.1 - 1.2e-16 61.0 1.1 0.00021 21.8 0.0 7.1 4 3 3 7 7 7 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORX94912.1 - 7.8e-15 55.3 6.1 8.7e-05 22.6 0.1 5.8 3 3 3 6 6 6 5 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORX94912.1 - 1.6e-11 44.5 15.3 0.0017 18.8 0.1 9.6 8 4 2 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.20 ORX94912.1 - 2.5e-10 39.6 11.2 2.3e-05 23.2 1.5 3.3 1 1 1 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 ORX94912.1 - 1.3e-06 28.6 9.9 0.069 13.3 0.1 5.5 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 ORX94912.1 - 1.5e-06 27.9 2.0 0.016 14.8 0.1 4.7 1 1 2 4 4 4 2 CLASP N terminal IFRD PF05004.13 ORX94912.1 - 0.00038 19.7 4.6 0.0058 15.8 0.1 4.1 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 ORX94912.1 - 0.00079 19.9 0.6 29 5.7 0.0 6.2 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat DNA_alkylation PF08713.11 ORX94912.1 - 0.0073 16.0 0.5 0.49 10.1 0.2 3.2 2 1 0 2 2 2 1 DNA alkylation repair enzyme M11L PF11099.8 ORX94912.1 - 0.036 14.4 5.4 8.3 6.7 0.0 4.5 4 2 2 6 6 6 0 Apoptosis regulator M11L like V-ATPase_H_N PF03224.14 ORX94912.1 - 0.058 12.7 5.3 1.3 8.2 0.2 4.1 2 1 2 4 4 4 0 V-ATPase subunit H NopRA1 PF16201.5 ORX94912.1 - 0.094 12.3 0.4 2.1 7.9 0.0 3.2 4 1 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Ecm29 PF13001.7 ORX94912.1 - 0.72 8.5 16.4 4.4 5.9 0.3 5.1 5 1 0 6 6 6 0 Proteasome stabiliser Mem_trans PF03547.18 ORX94913.1 - 1.6e-30 105.8 0.1 2.7e-30 105.1 0.1 1.3 1 1 0 1 1 1 1 Membrane transport protein Hexokinase_2 PF03727.16 ORX94914.1 - 8.3e-82 274.2 0.0 1.2e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX94914.1 - 8.5e-74 247.8 0.0 1.3e-73 247.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase TPP_enzyme_N PF02776.18 ORX94914.1 - 0.097 12.3 0.3 0.28 10.8 0.1 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ROK PF00480.20 ORX94914.1 - 0.11 12.0 0.3 0.79 9.1 0.0 2.2 2 1 0 2 2 2 0 ROK family Sugar_tr PF00083.24 ORX94915.1 - 3.8e-114 382.0 25.6 4.5e-114 381.8 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94915.1 - 1.3e-31 109.8 33.9 9.3e-31 107.0 32.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94915.1 - 3.3e-10 39.0 17.3 5e-09 35.1 4.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94916.1 - 6.4e-114 381.3 25.4 7.4e-114 381.1 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94916.1 - 1e-31 110.2 34.0 1.3e-30 106.5 33.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX94916.1 - 9.1e-11 40.9 14.6 5e-09 35.1 4.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94917.1 - 8.4e-109 364.4 25.3 1e-108 364.1 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94917.1 - 5.9e-27 94.5 32.2 5.9e-27 94.5 32.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94917.1 - 3.8e-07 28.9 2.8 3.8e-07 28.9 2.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94918.1 - 9.5e-115 384.0 23.8 1.1e-114 383.8 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94918.1 - 9.8e-32 110.2 34.2 1.3e-30 106.5 33.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX94918.1 - 9.2e-11 40.9 14.6 5e-09 35.1 4.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Hexokinase_2 PF03727.16 ORX94919.1 - 4.6e-82 275.0 0.0 6.6e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX94919.1 - 3.6e-73 245.7 0.0 6.5e-73 244.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase ROK PF00480.20 ORX94919.1 - 0.051 13.0 0.6 11 5.4 0.0 2.6 3 0 0 3 3 3 0 ROK family WGG PF10273.9 ORX94919.1 - 0.098 13.3 0.0 0.77 10.5 0.0 2.4 2 1 0 2 2 2 0 Pre-rRNA-processing protein TSR2 TPP_enzyme_N PF02776.18 ORX94919.1 - 0.75 9.4 2.9 0.36 10.4 0.2 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Sugar_tr PF00083.24 ORX94920.1 - 2e-112 376.4 23.7 2.5e-112 376.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94920.1 - 4.7e-29 101.4 36.0 5.9e-29 101.1 33.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94920.1 - 1.4e-07 30.4 14.4 1.9e-05 23.3 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94921.1 - 1.4e-112 376.8 23.9 1.8e-112 376.5 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94921.1 - 2e-29 102.6 36.3 2.6e-29 102.3 34.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94921.1 - 1.1e-07 30.6 14.4 1.9e-05 23.3 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94922.1 - 2e-112 376.4 23.7 2.5e-112 376.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94922.1 - 4.7e-29 101.4 36.0 5.9e-29 101.1 33.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94922.1 - 1.3e-07 30.4 14.4 1.9e-05 23.3 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94923.1 - 7.1e-116 387.7 30.6 7.1e-113 377.8 22.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORX94923.1 - 5.2e-29 101.3 42.9 1.2e-28 100.1 33.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX94923.1 - 8.3e-07 27.8 14.8 8.1e-05 21.2 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94924.1 - 1.1e-112 377.2 23.7 1.3e-112 377.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94924.1 - 3.5e-29 101.8 36.1 5.9e-29 101.1 33.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94924.1 - 1.9e-07 29.9 14.7 1.9e-05 23.3 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94925.1 - 1.1e-112 377.2 23.7 1.3e-112 377.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94925.1 - 3.5e-29 101.8 36.1 5.9e-29 101.1 33.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94925.1 - 1.9e-07 29.9 14.7 1.9e-05 23.3 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX94926.1 - 1.2e-113 380.4 20.6 1.4e-113 380.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX94926.1 - 2.6e-28 99.0 31.8 2.8e-28 98.9 28.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX94926.1 - 1.8e-07 30.0 2.8 1.8e-07 30.0 2.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3784 PF12650.7 ORX94926.1 - 0.023 14.9 1.6 0.023 14.9 1.6 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3784) Phage_holin_3_2 PF04550.12 ORX94926.1 - 7.2 7.2 11.0 0.59 10.7 4.0 2.8 2 0 0 2 2 2 0 Phage holin family 2 AMP-binding PF00501.28 ORX94939.1 - 4.6e-193 641.6 0.0 1.1e-97 327.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ORX94939.1 - 7.6e-110 367.7 0.0 4.5e-59 200.3 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 ORX94939.1 - 1.5e-30 105.3 0.6 4.8e-15 55.7 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 ORX94939.1 - 7.1e-27 95.0 0.0 2.2e-26 93.4 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 ORX94939.1 - 1e-25 90.5 0.7 3.9e-12 47.0 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 ORX94939.1 - 0.0013 19.3 0.6 0.016 15.8 0.1 3.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX94939.1 - 0.041 13.5 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LPMO_10 PF03067.15 ORX94940.1 - 0.00059 20.5 0.6 0.0038 17.9 0.6 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX94940.1 - 0.0025 17.8 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 GPI-anchored PF10342.9 ORX94940.1 - 0.023 15.5 0.0 0.038 14.7 0.0 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_61 PF03443.14 ORX94941.1 - 0.012 15.5 0.1 0.45 10.4 0.1 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORX94941.1 - 0.016 15.8 0.7 0.19 12.3 0.7 2.0 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Mob_synth_C PF06463.13 ORX94942.1 - 2.7e-40 137.3 0.0 7.3e-40 135.9 0.0 1.7 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ORX94942.1 - 3e-35 122.0 1.1 9.5e-35 120.4 0.3 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 ORX94942.1 - 3.4e-08 33.9 0.0 8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORX94942.1 - 2.9e-05 24.2 0.0 0.00011 22.3 0.0 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain UvrA_inter PF17760.1 ORX94942.1 - 0.0083 16.2 0.3 0.38 10.8 0.1 2.3 2 0 0 2 2 2 1 UvrA interaction domain Transferase PF02458.15 ORX94943.1 - 1.5e-65 221.6 0.0 1.7e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family Pkinase PF00069.25 ORX94944.1 - 1e-63 215.2 0.0 3.9e-63 213.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX94944.1 - 3.8e-27 95.2 0.1 3.3e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX94944.1 - 5.8e-06 25.5 0.0 8.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX94944.1 - 0.0011 18.9 0.2 0.11 12.4 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX94944.1 - 0.0025 17.2 0.0 0.0076 15.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX94944.1 - 0.011 15.1 0.7 0.043 13.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 ORX94944.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 ORX94944.1 - 0.044 14.5 0.3 0.099 13.4 0.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 ORX94944.1 - 0.076 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S41 PF03572.18 ORX94945.1 - 3.7e-09 36.4 0.0 7.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 SNAP PF14938.6 ORX94946.1 - 1.1e-33 116.9 3.2 1.5e-33 116.5 3.2 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP ANAPC5 PF12862.7 ORX94946.1 - 0.00062 19.8 0.7 0.0031 17.6 0.2 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 ORX94946.1 - 0.00081 19.6 1.4 0.6 10.4 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX94946.1 - 0.0028 17.6 9.7 0.041 14.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.9 ORX94946.1 - 0.012 15.4 2.1 0.031 14.0 2.1 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DnaJ PF00226.31 ORX94946.1 - 0.019 15.1 0.1 0.34 11.1 0.0 2.7 2 0 0 2 2 2 0 DnaJ domain TPR_14 PF13428.6 ORX94946.1 - 0.03 15.1 0.0 1.3 10.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NSF PF02071.20 ORX94946.1 - 0.16 12.8 7.5 7.8 7.8 0.0 4.3 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat SRP_TPR_like PF17004.5 ORX94946.1 - 0.27 11.3 3.7 0.15 12.1 0.7 2.2 2 1 0 2 2 2 0 Putative TPR-like repeat TPR_8 PF13181.6 ORX94946.1 - 0.4 11.0 0.0 0.4 11.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 ORX94946.1 - 0.48 10.5 8.3 15 5.7 3.3 4.0 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 ORX94947.1 - 3.1e-151 503.9 0.1 2.8e-149 497.4 0.0 2.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 ORX94947.1 - 5.2e-05 23.7 2.2 0.74 10.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX94947.1 - 0.0052 16.9 8.6 2.6 8.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX94947.1 - 0.011 15.9 0.7 0.011 15.9 0.7 2.8 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORX94947.1 - 0.1 13.5 4.3 98 4.2 0.1 4.8 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX94947.1 - 0.36 11.0 10.6 4.5 7.6 0.3 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat PolyA_pol PF01743.20 ORX94947.1 - 1.3 9.5 3.1 2.9 8.4 2.3 2.1 2 0 0 2 2 2 0 Poly A polymerase head domain TPR_6 PF13174.6 ORX94947.1 - 4.8 8.0 7.2 1.3e+02 3.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3421 PF11901.8 ORX94948.1 - 5.2e-34 116.7 5.9 9.5e-17 61.0 0.1 2.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3421 PF11901.8 ORX94949.1 - 1.3e-35 121.9 3.6 7e-19 67.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Spt20 PF12090.8 ORX94949.1 - 0.79 9.3 5.1 0.94 9.0 5.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF3421 PF11901.8 ORX94950.1 - 8.5e-35 119.2 4.1 3.5e-18 65.7 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) bZIP_1 PF00170.21 ORX94952.1 - 1.1e-10 41.4 11.4 2.2e-10 40.5 11.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX94952.1 - 1.1e-06 28.6 9.1 1.1e-06 28.6 9.1 2.3 1 1 1 2 2 2 1 Basic region leucine zipper YabA PF06156.13 ORX94952.1 - 4.2e-06 27.3 0.6 7.7e-06 26.5 0.6 1.5 1 0 0 1 1 1 1 Initiation control protein YabA SOGA PF11365.8 ORX94952.1 - 6.2e-05 24.1 0.7 0.00054 21.0 0.2 2.1 2 0 0 2 2 2 1 Protein SOGA bZIP_Maf PF03131.17 ORX94952.1 - 0.00023 21.6 8.5 0.00045 20.7 8.5 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor HMMR_N PF15905.5 ORX94952.1 - 0.0008 19.0 1.6 0.00095 18.7 1.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 ORX94952.1 - 0.0013 18.6 1.2 0.0015 18.4 1.2 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fez1 PF06818.15 ORX94952.1 - 0.0034 17.9 2.1 0.0042 17.6 2.1 1.2 1 0 0 1 1 1 1 Fez1 SHE3 PF17078.5 ORX94952.1 - 0.0038 17.0 0.8 0.0055 16.5 0.8 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF2400 PF09674.10 ORX94952.1 - 0.0042 17.1 0.4 0.0057 16.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) TMF_TATA_bd PF12325.8 ORX94952.1 - 0.0047 17.1 3.0 0.0086 16.3 3.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 ORX94952.1 - 0.0056 16.0 3.2 0.008 15.5 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Phlebovirus_NSM PF07246.11 ORX94952.1 - 0.0061 16.0 1.8 0.0075 15.7 1.8 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Filament PF00038.21 ORX94952.1 - 0.0062 16.2 2.8 0.0078 15.8 2.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF812 PF05667.11 ORX94952.1 - 0.0094 14.9 4.0 0.011 14.6 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) RasGAP_C PF03836.15 ORX94952.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 0 RasGAP C-terminus KASH_CCD PF14662.6 ORX94952.1 - 0.012 15.5 3.4 0.012 15.5 3.4 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH EzrA PF06160.12 ORX94952.1 - 0.013 13.7 4.5 0.017 13.3 4.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 ORX94952.1 - 0.013 15.3 0.8 0.021 14.7 0.8 1.2 1 0 0 1 1 1 0 Sec34-like family DUF1515 PF07439.11 ORX94952.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF641 PF04859.12 ORX94952.1 - 0.016 15.5 2.0 0.024 15.0 2.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1640 PF07798.11 ORX94952.1 - 0.018 15.1 2.6 0.028 14.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3584 PF12128.8 ORX94952.1 - 0.019 12.5 2.5 0.023 12.2 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2205 PF10224.9 ORX94952.1 - 0.019 14.9 5.7 0.43 10.6 5.7 2.2 1 1 0 1 1 1 0 Short coiled-coil protein ZapB PF06005.12 ORX94952.1 - 0.021 15.2 4.0 0.021 15.2 4.0 1.6 2 0 0 2 2 1 0 Cell division protein ZapB FlxA PF14282.6 ORX94952.1 - 0.025 14.6 2.1 0.025 14.6 2.1 1.8 1 1 0 1 1 1 0 FlxA-like protein Macoilin PF09726.9 ORX94952.1 - 0.033 12.8 2.1 0.032 12.8 2.1 1.2 1 0 0 1 1 1 0 Macoilin family Chibby PF14645.6 ORX94952.1 - 0.036 14.5 3.0 0.057 13.8 3.0 1.3 1 0 0 1 1 1 0 Chibby family UPF0242 PF06785.11 ORX94952.1 - 0.036 14.2 5.0 0.051 13.7 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 ORX94952.1 - 0.036 12.0 1.5 0.038 11.9 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.6 ORX94952.1 - 0.037 14.1 2.6 0.45 10.6 0.1 2.7 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 EMP24_GP25L PF01105.24 ORX94952.1 - 0.038 13.9 2.0 0.053 13.5 2.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Herpes_UL6 PF01763.16 ORX94952.1 - 0.043 12.4 0.4 0.049 12.1 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CC2-LZ PF16516.5 ORX94952.1 - 0.044 14.2 3.7 0.063 13.6 3.7 1.2 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF16 PF01519.16 ORX94952.1 - 0.05 14.1 1.7 0.078 13.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Cluap1 PF10234.9 ORX94952.1 - 0.052 12.9 4.0 0.069 12.5 4.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 MPS2 PF17060.5 ORX94952.1 - 0.063 12.5 2.7 0.084 12.1 2.7 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 APG6_N PF17675.1 ORX94952.1 - 0.063 13.8 6.6 0.1 13.1 6.6 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 ORX94952.1 - 0.07 13.4 1.2 0.07 13.4 1.2 2.1 2 1 0 2 2 1 0 Homeobox associated leucine zipper DUF4407 PF14362.6 ORX94952.1 - 0.071 12.5 1.0 0.084 12.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 ORX94952.1 - 0.073 13.5 0.8 0.26 11.7 0.8 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 ORX94952.1 - 0.076 13.4 4.9 0.077 13.4 3.5 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 ORX94952.1 - 0.083 13.4 0.4 0.18 12.3 0.1 1.7 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.9 ORX94952.1 - 0.11 12.8 6.6 0.024 14.9 2.9 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein ADIP PF11559.8 ORX94952.1 - 0.12 12.4 8.5 0.26 11.4 8.5 1.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BESS PF02944.20 ORX94952.1 - 0.15 11.9 0.2 0.33 10.8 0.2 1.6 1 0 0 1 1 1 0 BESS motif SKA1 PF07160.12 ORX94952.1 - 0.18 11.6 6.9 0.077 12.8 4.3 1.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1319 PF07028.11 ORX94952.1 - 0.2 11.9 2.5 0.43 10.8 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) FapA PF03961.13 ORX94952.1 - 0.21 10.2 1.8 0.25 9.9 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 ORX94952.1 - 0.22 11.7 11.0 0.04 14.1 6.8 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 ORX94952.1 - 0.25 11.5 5.4 0.2 11.7 3.7 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3573 PF12097.8 ORX94952.1 - 0.25 10.1 0.2 0.3 9.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ABC_tran_CTD PF16326.5 ORX94952.1 - 0.33 11.2 3.7 0.63 10.3 3.7 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain THOC7 PF05615.13 ORX94952.1 - 0.34 11.2 8.0 0.6 10.4 8.0 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 Swi5 PF07061.11 ORX94952.1 - 0.52 10.4 3.5 0.43 10.7 1.6 1.9 2 1 0 2 2 1 0 Swi5 TSC22 PF01166.18 ORX94952.1 - 0.79 10.1 5.1 1.2 9.6 0.2 2.7 3 1 1 4 4 2 0 TSC-22/dip/bun family Cep57_MT_bd PF06657.13 ORX94952.1 - 0.89 10.1 5.4 0.5 10.8 0.8 2.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 ORX94952.1 - 2.4 8.0 6.3 6.7 6.5 6.0 1.9 1 1 0 1 1 1 0 Septum formation initiator ORC2 PF04084.14 ORX94954.1 - 5.8e-115 383.7 0.6 7.3e-115 383.4 0.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PseudoU_synth_1 PF01416.20 ORX94955.1 - 1.3e-09 38.5 0.0 2.4e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase HydF_dimer PF18128.1 ORX94955.1 - 0.05 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain PBP1_TM PF14812.6 ORX94955.1 - 0.055 13.8 8.3 0.13 12.7 8.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trehalase PF01204.18 ORX94956.1 - 1.3e-129 433.3 5.1 3.7e-117 392.2 0.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 ORX94956.1 - 0.00011 21.3 0.6 0.0002 20.4 0.5 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase 3-alpha PF03475.14 ORX94956.1 - 0.21 11.5 0.7 5.4 7.0 0.1 2.7 2 0 0 2 2 2 0 3-alpha domain PUL PF08324.11 ORX94957.1 - 3.5e-52 177.4 6.8 4.8e-52 176.9 6.8 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 ORX94957.1 - 9.7e-44 146.5 12.9 9.1e-08 32.7 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.11 ORX94957.1 - 3.6e-41 140.0 0.7 9.8e-41 138.6 0.7 1.8 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.6 ORX94957.1 - 0.049 13.7 0.0 6.3 6.9 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region V-ATPase_H_C PF11698.8 ORX94957.1 - 0.058 13.5 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 V-ATPase subunit H FGGY_C PF02782.16 ORX94958.1 - 1.2e-50 172.0 0.1 2e-50 171.3 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORX94958.1 - 2.4e-28 99.3 0.3 1e-27 97.3 0.0 2.3 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ORX94958.1 - 8.9e-09 35.2 1.1 2.8e-05 23.7 0.1 2.7 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DAAD PF18752.1 ORX94959.1 - 0.01 15.7 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase zf-CCCH PF00642.24 ORX94959.1 - 4.8 7.2 7.7 1.2 9.1 4.0 2.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPMT PF05724.11 ORX94961.1 - 1.2e-39 136.2 0.0 1.5e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 ORX94961.1 - 2.4e-05 25.0 0.0 4.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX94961.1 - 0.00037 21.1 0.0 0.00071 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX94961.1 - 0.00046 20.9 0.0 0.0007 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX94961.1 - 0.0077 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX94961.1 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ArAE_2 PF10334.9 ORX94964.1 - 4.2e-16 59.5 0.0 5.7e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORX94964.1 - 1.3e-10 41.5 13.8 1.3e-10 41.5 13.8 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 ORX94964.1 - 4.4e-10 39.2 26.6 2e-09 37.0 1.8 3.5 3 1 1 4 4 4 3 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ORX94964.1 - 2.1e-08 33.5 2.9 2.1e-08 33.5 2.9 2.4 2 0 0 2 2 2 1 Aluminium activated malate transporter CCDC14 PF15254.6 ORX94966.1 - 7.4 5.1 5.8 8 5.0 5.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Methyltransf_3 PF01596.17 ORX94967.1 - 6e-18 64.8 0.0 7.6e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX94967.1 - 3.1e-08 34.6 0.0 4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ORX94967.1 - 0.0015 18.2 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 ORX94967.1 - 0.03 14.1 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.22 ORX94968.1 - 6.1e-14 52.9 0.0 9.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX94968.1 - 3.4e-06 27.0 0.1 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain C2 PF00168.30 ORX94970.1 - 1.3e-14 54.3 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 C2 domain RGS PF00615.19 ORX94971.1 - 0.0027 18.0 0.3 0.017 15.4 0.3 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain Tox-MPTase4 PF15640.6 ORX94971.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 4 DUF2892 PF11127.8 ORX94971.1 - 0.67 10.0 3.1 2.3 8.3 3.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) Tim17 PF02466.19 ORX94972.1 - 1.4e-11 44.7 5.5 1.4e-11 44.7 5.5 1.7 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Dev_Cell_Death PF10539.9 ORX94972.1 - 0.098 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain Oxysterol_BP PF01237.18 ORX94973.1 - 7.4e-133 443.0 1.1 2.2e-132 441.4 1.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 ORX94973.1 - 4.1e-14 52.6 0.1 4e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORX94973.1 - 0.0016 18.9 0.2 0.0078 16.7 0.1 2.3 2 1 0 2 2 2 1 PH domain Ribosomal_S9 PF00380.19 ORX94974.1 - 6e-34 117.2 0.2 6.8e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Homeodomain PF00046.29 ORX94975.1 - 1.2e-20 73.0 2.9 1.9e-20 72.5 2.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX94975.1 - 0.00067 19.5 0.7 0.0014 18.4 0.2 1.8 2 0 0 2 2 2 1 Homeobox KN domain MarR PF01047.22 ORX94975.1 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 ORX94975.1 - 0.086 12.4 0.0 0.49 10.0 0.0 1.9 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyclin PF08613.11 ORX94976.1 - 1.4e-14 54.7 0.0 1.8e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX94976.1 - 1.1e-11 44.6 0.0 1.2e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ferritin PF00210.24 ORX94977.1 - 1.8e-40 138.1 0.2 2.1e-40 137.9 0.2 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ORX94977.1 - 6.9e-06 26.5 0.0 9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin PPV_E2_N PF00508.17 ORX94977.1 - 0.02 14.3 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal U5_2-snRNA_bdg PF10597.9 ORX94977.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 YtxH PF12732.7 ORX94978.1 - 0.00065 20.2 2.0 2.4 8.8 0.0 3.5 1 1 1 2 2 2 2 YtxH-like protein LEA_4 PF02987.16 ORX94978.1 - 0.02 14.9 2.7 0.39 10.8 1.1 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein Sad1_UNC PF07738.13 ORX94979.1 - 1.8e-37 128.3 0.0 2.5e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EI24 PF07264.11 ORX94980.1 - 2.2e-15 57.3 17.6 2.7e-15 57.0 17.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2871 PF11070.8 ORX94980.1 - 0.037 14.3 1.1 0.098 12.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) MFS_MOT1 PF16983.5 ORX94981.1 - 2.8e-58 195.1 30.0 1.9e-31 108.7 7.7 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 ORX94981.1 - 3.1e-06 26.2 20.0 2.3e-05 23.3 20.0 2.3 1 1 0 1 1 1 1 Sulfate permease family TPPK_C PF12555.8 ORX94981.1 - 0.55 10.3 3.1 0.54 10.3 0.2 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF2569 PF10754.9 ORX94981.1 - 0.65 10.4 7.8 0.14 12.6 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) GDP_Man_Dehyd PF16363.5 ORX94982.1 - 1.6e-54 185.6 0.0 2.3e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX94982.1 - 2.9e-53 180.8 0.0 3.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX94982.1 - 6.2e-16 58.2 0.0 1.3e-15 57.2 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORX94982.1 - 8.5e-13 48.1 0.0 1.5e-12 47.3 0.0 1.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ORX94982.1 - 1.9e-11 43.8 0.0 3.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX94982.1 - 1.4e-09 38.1 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 ORX94982.1 - 1.3e-07 31.1 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORX94982.1 - 7.1e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 ORX94982.1 - 0.00029 20.5 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 ORX94982.1 - 0.0031 16.7 0.0 0.52 9.4 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 ORX94982.1 - 0.0032 17.0 0.0 0.0091 15.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ORX94982.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 ORX94982.1 - 0.0081 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 ORX94982.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ORX94982.1 - 0.055 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 ORX94983.1 - 7.5e-11 42.3 0.0 1.8e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain WTF PF03303.13 ORX94983.1 - 0.0092 15.7 1.7 0.017 14.9 1.7 1.4 1 0 0 1 1 1 1 WTF protein bZIP_1 PF00170.21 ORX94984.1 - 4.8e-11 42.6 6.7 6.5e-11 42.2 6.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX94984.1 - 1.3e-08 34.8 7.3 2.5e-08 33.8 6.4 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX94984.1 - 5e-06 26.9 4.6 6.1e-06 26.7 4.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor NRBF2 PF08961.10 ORX94984.1 - 0.0065 16.1 2.2 0.0096 15.5 1.2 1.7 1 1 1 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 ORX94984.1 - 0.011 16.0 0.6 0.019 15.1 0.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Tom37 PF10568.9 ORX94984.1 - 0.045 14.0 0.1 0.047 14.0 0.1 1.1 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein NIBRIN_BRCT_II PF16508.5 ORX94984.1 - 0.082 13.2 0.3 0.095 13.0 0.3 1.1 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein NYD-SP28_assoc PF14775.6 ORX94984.1 - 0.15 12.1 7.1 0.23 11.6 6.1 2.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain ZapB PF06005.12 ORX94984.1 - 1.1 9.7 11.9 0.44 11.0 2.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 ORX94984.1 - 2 8.3 6.5 1.1 9.1 4.2 1.9 1 1 1 2 2 2 0 Septum formation initiator S1-P1_nuclease PF02265.16 ORX94986.1 - 2.4e-66 224.1 0.1 2.7e-66 224.0 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Gpr1_Fun34_YaaH PF01184.19 ORX94987.1 - 5.1e-75 251.6 21.3 5.6e-75 251.5 21.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TMEM190 PF15431.6 ORX94988.1 - 0.012 15.7 0.2 0.012 15.7 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 190 VEGFR-2_TMD PF17988.1 ORX94988.1 - 0.014 14.8 1.5 0.023 14.1 1.5 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain TMEM51 PF15345.6 ORX94988.1 - 0.061 13.2 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 BatA PF07584.11 ORX94988.1 - 0.073 13.4 0.2 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal MAS20 PF02064.15 ORX94988.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor Polysacc_deac_1 PF01522.21 ORX94989.1 - 7.6e-28 96.9 0.0 1.2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX94989.1 - 0.014 14.6 0.0 0.086 12.0 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 PAP_PilO PF06864.12 ORX94989.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.3 1 1 0 1 1 1 0 Pilin accessory protein (PilO) Choline_transpo PF04515.12 ORX94990.1 - 6.5e-07 28.9 26.6 7.7e-06 25.3 6.3 3.4 2 1 1 3 3 3 3 Plasma-membrane choline transporter Arrestin_C PF02752.22 ORX94991.1 - 2.2e-13 50.8 0.0 3.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Thioredoxin PF00085.20 ORX94992.1 - 2.5e-30 104.5 0.1 2.9e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORX94992.1 - 1.7e-06 28.4 0.1 3.4e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORX94992.1 - 1.2e-05 25.6 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORX94992.1 - 1.8e-05 24.7 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX94992.1 - 3.7e-05 23.5 0.2 5.3e-05 23.0 0.2 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 ORX94992.1 - 0.00048 19.9 0.0 0.00057 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 ORX94992.1 - 0.0016 18.6 0.0 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ORX94992.1 - 0.0047 16.3 0.1 0.0051 16.2 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Nucleocap_ssRNA PF11128.8 ORX94992.1 - 0.01 15.6 0.1 0.022 14.5 0.0 1.6 1 1 0 1 1 1 0 Plant viral coat protein nucleocapsid Nramp PF01566.18 ORX94993.1 - 4.4e-117 391.1 19.1 6.9e-117 390.4 19.1 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein MINDY_DUB PF04424.13 ORX95011.1 - 5.3e-31 107.1 0.0 1.8e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 MINDY deubiquitinase PX PF00787.24 ORX95012.1 - 2.7e-19 69.2 0.0 5.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 PX domain EF-hand_4 PF12763.7 ORX95012.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Cyclin_N PF00134.23 ORX95013.1 - 6e-07 29.3 0.0 7.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX95013.1 - 1.7e-06 28.5 0.0 2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Tom37 PF10568.9 ORX95013.1 - 0.055 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PET117 PF15786.5 ORX95014.1 - 3.1e-21 75.4 4.1 3.6e-21 75.2 4.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Aa_trans PF01490.18 ORX95015.1 - 2.2e-64 217.7 35.7 2.5e-64 217.5 35.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PLDc_2 PF13091.6 ORX95016.1 - 2.4e-16 59.8 0.3 2.4e-10 40.4 0.6 3.2 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORX95016.1 - 5.5e-16 58.0 1.8 2.8e-08 33.6 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 ORX95016.1 - 2.9e-11 43.4 0.7 7.8e-11 42.0 0.7 1.7 1 0 0 1 1 1 1 PX domain PH PF00169.29 ORX95016.1 - 1.1e-06 29.0 0.3 2.8e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 PH domain DUF202 PF02656.15 ORX95017.1 - 2.5e-13 50.2 1.9 2.5e-13 50.2 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Na_H_Exchanger PF00999.21 ORX95017.1 - 0.013 14.4 3.1 0.015 14.1 3.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family DUF3040 PF11239.8 ORX95017.1 - 0.072 13.4 0.2 0.62 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 ORX95017.1 - 0.76 8.5 5.6 1.3 7.6 5.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) VTC PF09359.10 ORX95018.1 - 3.1e-102 341.7 0.6 3.1e-102 341.7 0.6 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 ORX95018.1 - 6.4e-15 56.0 28.0 1.1e-06 28.9 0.5 4.3 2 1 2 4 4 4 4 SPX domain DUF202 PF02656.15 ORX95018.1 - 8.1e-15 55.0 1.7 1.5e-14 54.1 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) LXG PF04740.12 ORX95018.1 - 0.019 14.7 3.0 0.1 12.3 0.1 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily TMF_DNA_bd PF12329.8 ORX95018.1 - 0.032 14.2 6.1 0.62 10.1 0.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 ORX95018.1 - 0.42 10.7 3.5 0.6 10.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 ORX95018.1 - 0.68 9.3 12.1 0.92 8.8 4.6 2.2 2 0 0 2 2 2 0 Tropomyosin XhlA PF10779.9 ORX95018.1 - 2.2 8.5 5.2 5.8 7.2 0.6 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 ORX95018.1 - 6.3 7.3 7.9 9.7 6.7 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_18 PF13238.6 ORX95019.1 - 1.6e-25 90.1 0.1 2.5e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORX95019.1 - 1.5e-06 28.6 0.1 5.4e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX95019.1 - 0.00014 22.1 0.0 0.16 12.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain ADK PF00406.22 ORX95019.1 - 0.00032 20.8 0.5 0.055 13.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 ORX95019.1 - 0.00075 19.8 0.2 0.0022 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORX95019.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 ORX95019.1 - 0.0074 16.6 0.5 0.033 14.5 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORX95019.1 - 0.0091 16.4 0.1 0.039 14.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX95019.1 - 0.014 15.8 0.1 0.015 15.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX95019.1 - 0.016 15.5 0.1 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX95019.1 - 0.026 13.9 0.1 0.064 12.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 ORX95019.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 NTPase ATPase PF06745.13 ORX95019.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 KaiC TniB PF05621.11 ORX95019.1 - 0.036 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 ORX95019.1 - 0.038 13.3 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 ORX95019.1 - 0.09 12.8 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ORX95019.1 - 0.14 11.9 0.2 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORX95019.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ORX95019.1 - 0.18 11.5 2.9 0.16 11.6 0.5 2.1 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORX95019.1 - 0.21 11.3 0.3 0.35 10.5 0.3 1.3 1 0 0 1 1 1 0 AAA domain CLTH PF10607.9 ORX95020.1 - 4.2e-31 107.8 0.0 6.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 ORX95020.1 - 4.1e-24 85.0 0.3 6.1e-24 84.4 0.3 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 ORX95020.1 - 2.9e-07 30.2 0.0 7.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 LisH Mid1 PF12929.7 ORX95021.1 - 4e-47 161.4 11.1 1.3e-41 143.2 13.7 2.7 2 1 0 2 2 2 2 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 ORX95021.1 - 0.029 15.0 6.4 0.09 13.4 1.5 2.5 2 0 0 2 2 2 0 Fz domain ubiquitin PF00240.23 ORX95022.1 - 2e-07 30.7 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX95022.1 - 0.00066 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORX95022.1 - 0.045 14.3 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PhoLip_ATPase_C PF16212.5 ORX95023.1 - 7.2e-60 202.8 22.3 7.2e-60 202.8 22.3 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORX95023.1 - 8.1e-18 63.9 4.8 8.1e-18 63.9 4.8 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORX95023.1 - 9.4e-12 44.9 0.1 2.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORX95023.1 - 1.6e-10 40.8 0.1 5.1e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORX95023.1 - 2.4e-07 31.3 0.1 0.0066 16.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX95023.1 - 0.0013 18.5 0.1 0.015 15.0 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ALIX_LYPXL_bnd PF13949.6 ORX95024.1 - 8.4e-05 22.0 2.3 9.4e-05 21.8 2.3 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CopG_antitoxin PF12441.8 ORX95024.1 - 0.054 14.0 0.7 0.098 13.2 0.7 1.5 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system Sec20 PF03908.13 ORX95024.1 - 0.084 12.8 0.7 0.19 11.7 0.5 1.6 1 1 0 1 1 1 0 Sec20 ZapB PF06005.12 ORX95024.1 - 0.13 12.7 9.9 0.23 11.9 9.9 1.4 1 0 0 1 1 1 0 Cell division protein ZapB zf_CCCH_4 PF18345.1 ORX95025.1 - 1.3e-21 75.9 53.3 7.7e-07 29.0 2.6 5.8 6 0 0 6 6 6 5 Zinc finger domain zf-CCCH PF00642.24 ORX95025.1 - 2e-20 72.2 37.0 2.2e-06 27.4 0.5 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORX95025.1 - 6.4e-17 62.2 26.2 5.8e-05 23.7 1.0 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 ORX95025.1 - 1.2e-12 47.3 38.6 3.5e-06 26.7 0.3 5.4 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 ORX95025.1 - 2e-07 31.2 24.9 4.3e-06 26.9 5.3 3.8 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCHC PF00098.23 ORX95025.1 - 2.3e-06 27.4 4.7 2.5e-06 27.3 1.9 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 ORX95025.1 - 0.00016 22.0 44.3 0.46 11.0 1.0 5.8 6 0 0 6 6 6 5 RNA-binding, Nab2-type zinc finger zf-CCHC_2 PF13696.6 ORX95025.1 - 0.1 12.5 6.9 0.093 12.6 2.8 2.8 2 0 0 2 2 2 0 Zinc knuckle Ntox16 PF15523.6 ORX95025.1 - 2.8 8.2 14.5 1.8 8.9 0.1 3.5 1 1 1 3 3 3 0 Novel toxin 16 Glyco_transf_20 PF00982.21 ORX95026.1 - 2.8e-197 656.1 0.0 3.4e-197 655.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORX95026.1 - 5.6e-56 189.3 0.0 1.2e-55 188.2 0.0 1.5 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORX95026.1 - 0.00042 20.1 0.0 0.13 12.0 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 ORX95026.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Bclx_interact PF08945.10 ORX95026.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Peptidase_S8 PF00082.22 ORX95027.1 - 4.5e-54 183.7 0.0 6.2e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORX95027.1 - 7.4e-12 46.0 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Fn3-like domain Inhibitor_I9 PF05922.16 ORX95027.1 - 0.0013 19.4 0.0 0.0071 17.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 RPT PF13446.6 ORX95027.1 - 0.2 11.6 0.1 0.54 10.2 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein PsbK PF02533.15 ORX95032.1 - 0.069 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component Peptidase_M13_N PF05649.13 ORX95033.1 - 2.7e-86 290.7 0.0 3.8e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX95033.1 - 1.1e-66 224.3 0.0 1.8e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 ORX95034.1 - 2.7e-64 218.2 0.0 3.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 AMP-binding PF00501.28 ORX95053.1 - 7.1e-71 239.0 0.1 4.1e-44 150.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ORX95053.1 - 3.2e-38 131.6 0.0 4.4e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 ORX95053.1 - 1.4e-11 45.2 0.0 2.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX95053.1 - 6.7e-11 42.4 0.0 1.8e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site zinc_ribbon_10 PF10058.9 ORX95054.1 - 0.015 15.0 4.8 0.028 14.1 4.8 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein ABC_membrane PF00664.23 ORX95055.1 - 7.3e-61 206.2 25.3 1.2e-34 120.2 4.6 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX95055.1 - 1.2e-44 152.2 0.0 4.5e-25 88.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX95055.1 - 7.6e-10 38.6 0.4 0.00015 21.3 0.0 4.5 4 2 2 6 6 6 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX95055.1 - 3.6e-05 24.4 0.2 0.17 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORX95055.1 - 0.00025 20.7 0.2 0.27 11.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX95055.1 - 0.00043 20.6 1.2 0.042 14.1 0.1 3.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORX95055.1 - 0.0014 18.6 0.3 0.1 12.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ORX95055.1 - 0.0031 17.1 0.3 0.93 9.0 0.1 2.7 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 ORX95055.1 - 0.0054 15.8 0.3 1.8 7.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 ORX95055.1 - 0.0099 16.3 0.7 2.5 8.5 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ORX95055.1 - 0.015 14.5 0.3 5.8 6.2 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 ORX95055.1 - 0.018 15.1 0.5 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 ORX95055.1 - 0.022 13.5 0.1 4.2 6.1 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.22 ORX95055.1 - 0.072 12.3 0.2 1 8.5 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 ORX95055.1 - 0.092 12.8 0.9 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 ORX95055.1 - 0.1 12.1 0.4 12 5.3 0.1 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_27 PF13514.6 ORX95055.1 - 0.13 11.8 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ORX95055.1 - 0.16 12.2 0.1 14 6.0 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ORX95055.1 - 0.3 11.7 0.6 30 5.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 ORX95055.1 - 0.41 10.3 2.1 26 4.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ORX95055.1 - 0.44 10.3 3.6 13 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 ORX95055.1 - 0.51 10.1 1.9 8 6.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein p450 PF00067.22 ORX95056.1 - 4.2e-53 180.7 4.8 3e-52 177.9 2.5 2.7 1 1 1 2 2 2 1 Cytochrome P450 Band_7 PF01145.25 ORX95057.1 - 5.8e-29 101.4 0.8 8.3e-29 100.8 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX95057.1 - 0.015 15.1 0.1 0.03 14.1 0.1 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family Sec7 PF01369.20 ORX95058.1 - 4.5e-36 124.2 0.0 5e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain Adeno_E3 PF06040.11 ORX95059.1 - 0.3 11.2 2.4 0.99 9.6 0.2 2.2 2 0 0 2 2 2 0 Adenovirus E3 protein CRT10 PF08728.10 ORX95059.1 - 1.1 7.3 7.7 1.3 7.1 7.7 1.0 1 0 0 1 1 1 0 CRT10 Phosphodiest PF01663.22 ORX95060.1 - 5.2e-12 46.0 0.0 7.5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORX95060.1 - 0.00036 20.0 0.1 0.0088 15.5 0.1 2.2 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 ORX95060.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily LapA_dom PF06305.11 ORX95060.1 - 0.045 13.6 0.2 0.045 13.6 0.2 4.3 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain PgaD PF13994.6 ORX95060.1 - 5.4 7.1 8.5 3.6 7.6 4.3 2.6 2 0 0 2 2 2 0 PgaD-like protein CLASP_N PF12348.8 ORX95061.1 - 5.5e-77 258.4 3.2 5.7e-61 206.0 0.0 4.8 4 1 0 4 4 4 4 CLASP N terminal HEAT PF02985.22 ORX95061.1 - 1.4e-15 56.0 0.1 0.099 13.0 0.0 7.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 ORX95061.1 - 4e-06 27.2 1.6 0.24 11.9 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat Tti2 PF10521.9 ORX95061.1 - 0.00073 19.2 0.5 0.049 13.2 0.1 3.1 2 1 1 3 3 3 1 Tti2 family Condensin2nSMC PF12422.8 ORX95061.1 - 0.0012 19.1 0.5 0.53 10.4 0.1 3.8 4 0 0 4 4 4 1 Condensin II non structural maintenance of chromosomes subunit NUC194 PF08163.12 ORX95061.1 - 0.003 16.5 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 NUC194 domain DRIM PF07539.12 ORX95061.1 - 0.0032 15.8 2.7 0.16 10.3 0.0 3.3 3 1 0 3 3 3 1 Down-regulated in metastasis Cnd1 PF12717.7 ORX95061.1 - 0.0041 17.2 2.2 20 5.2 0.1 5.2 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Importin_rep_4 PF18808.1 ORX95061.1 - 0.0063 16.8 2.9 0.13 12.5 0.1 3.7 4 0 0 4 4 3 1 Importin repeat DUF3361 PF11841.8 ORX95061.1 - 0.076 12.9 0.6 0.89 9.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) TAN PF11640.8 ORX95061.1 - 0.14 12.3 0.4 33 4.6 0.0 4.3 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair NUC173 PF08161.12 ORX95061.1 - 0.22 11.1 1.9 1.2 8.7 0.1 2.9 3 0 0 3 3 3 0 NUC173 domain Trypan_PARP PF05887.11 ORX95061.1 - 0.42 10.6 3.9 0.9 9.5 3.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HSP70 PF00012.20 ORX95062.1 - 2.9e-175 583.9 1.5 2.9e-175 583.9 1.5 1.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORX95062.1 - 4.8e-13 48.6 0.0 1.3e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 ORX95062.1 - 0.028 13.0 1.0 6.2 5.3 0.0 3.0 2 1 1 3 3 3 0 Actin pP_pnuc_2 PF18166.1 ORX95062.1 - 0.048 13.7 0.1 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease Raco_middle PF17651.1 ORX95062.1 - 0.11 12.1 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 RACo middle region Spectrin PF00435.21 ORX95062.1 - 0.28 11.7 4.7 4.7 7.7 1.1 2.9 2 0 0 2 2 2 0 Spectrin repeat AbrB_C PF18277.1 ORX95063.1 - 0.068 12.8 0.1 0.96 9.1 0.0 2.1 2 0 0 2 2 2 0 AbrB C-terminal domain DUF1853 PF08907.11 ORX95065.1 - 1.3e-30 107.1 0.0 8.6e-20 71.6 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1853) AMP-binding PF00501.28 ORX95070.1 - 0 1856.5 0.0 2.2e-95 319.7 0.0 6.4 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 ORX95070.1 - 0 1498.1 29.8 1.3e-56 192.2 0.0 10.6 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.25 ORX95070.1 - 7.1e-86 282.6 0.2 9.5e-13 48.3 0.0 7.6 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX95070.1 - 3.1e-42 143.4 0.5 3.9e-06 27.7 0.0 6.8 6 0 0 6 6 6 6 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 ORX95070.1 - 6.8e-27 95.1 0.1 2e-26 93.5 0.1 1.9 1 0 0 1 1 1 1 Thioesterase domain Transferase PF02458.15 ORX95070.1 - 3.5e-06 25.9 0.1 5.9 5.4 0.0 6.7 7 0 0 7 7 7 1 Transferase family DUF5122 PF17164.4 ORX95070.1 - 0.029 14.7 3.4 1.6e+02 2.6 0.0 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Ald_Xan_dh_C PF01315.22 ORX95070.1 - 0.037 14.4 0.1 0.24 11.8 0.1 2.4 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Abhydrolase_6 PF12697.7 ORX95070.1 - 0.064 13.9 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AMP-binding PF00501.28 ORX95071.1 - 0 2099.2 0.0 6.4e-95 318.2 0.0 7.5 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.20 ORX95071.1 - 0 1240.1 32.1 2.4e-58 197.9 0.0 15.1 11 4 3 14 14 14 14 Condensation domain PP-binding PF00550.25 ORX95071.1 - 6.8e-84 276.2 0.5 1.1e-12 48.1 0.0 8.2 8 0 0 8 8 8 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX95071.1 - 6.4e-50 168.0 6.2 3.4e-07 31.2 0.0 7.5 7 0 0 7 7 7 6 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 ORX95071.1 - 4.3e-24 85.9 0.0 1.3e-23 84.3 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Ald_Xan_dh_C PF01315.22 ORX95071.1 - 2.9e-06 27.6 0.5 0.17 12.2 0.1 2.9 2 0 0 2 2 2 2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Transferase PF02458.15 ORX95071.1 - 0.0018 17.0 0.4 17 3.9 0.0 6.0 7 0 0 7 7 7 0 Transferase family Abhydrolase_1 PF00561.20 ORX95071.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2688 PF10892.8 ORX95071.1 - 0.023 14.1 1.1 1.4e+02 2.0 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2688) DUF5122 PF17164.4 ORX95071.1 - 0.033 14.5 3.4 1.9e+02 2.4 0.0 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Peptidase_C28 PF05408.11 ORX95071.1 - 0.043 13.5 0.1 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase DUF998 PF06197.13 ORX95071.1 - 0.18 11.4 2.5 14 5.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF2205 PF10224.9 ORX95071.1 - 0.94 9.5 2.8 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 Short coiled-coil protein Palm_thioest PF02089.15 ORX95077.1 - 3e-08 33.8 0.0 6.8e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ORX95077.1 - 2.1e-07 30.7 0.0 3.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORX95077.1 - 4.6e-05 23.2 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORX95077.1 - 0.00011 21.9 0.1 0.0011 18.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 ORX95077.1 - 0.003 16.8 0.0 0.0073 15.5 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 ORX95077.1 - 0.023 14.0 0.0 0.082 12.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 ORX95077.1 - 0.12 11.9 0.2 1.7 8.1 0.0 2.5 2 1 0 2 2 2 0 Lipase (class 2) Lysine_decarbox PF03641.14 ORX95078.1 - 1.4e-37 128.7 1.1 1.6e-37 128.6 0.1 1.5 2 0 0 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ORX95078.1 - 1.7e-15 56.9 0.3 2.4e-15 56.5 0.3 1.4 1 1 0 1 1 1 1 SLOG cluster4 family zf-C2H2 PF00096.26 ORX95079.1 - 5.9e-12 45.3 10.2 6.3e-06 26.4 2.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95079.1 - 1.2e-09 38.1 9.4 0.00011 22.7 2.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX95079.1 - 4.4e-08 33.2 16.6 1.2e-07 31.8 1.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX95079.1 - 5.6e-08 32.9 1.5 5.3e-05 23.5 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX95079.1 - 1.3e-06 28.5 2.3 0.00028 21.1 0.8 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX95079.1 - 1.2e-05 25.2 6.4 8.9e-05 22.4 1.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 ORX95079.1 - 0.0035 17.3 4.8 0.1 12.7 0.5 2.2 1 1 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 ORX95079.1 - 0.0038 17.5 2.0 0.017 15.5 0.4 1.9 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX95079.1 - 0.0067 16.2 8.4 0.45 10.3 0.9 2.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 ORX95079.1 - 0.009 16.3 3.2 1.2 9.5 0.4 2.2 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 ORX95079.1 - 0.034 14.0 0.6 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 ORX95079.1 - 0.065 13.1 4.5 0.074 13.0 0.8 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-FPG_IleRS PF06827.14 ORX95079.1 - 0.083 12.8 2.3 2.1 8.3 0.4 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C2H2_11 PF16622.5 ORX95079.1 - 0.1 12.4 7.5 1.7 8.5 0.4 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type GAGA PF09237.11 ORX95079.1 - 0.42 10.4 3.6 0.49 10.2 2.3 1.8 1 1 1 2 2 2 0 GAGA factor Pkinase PF00069.25 ORX95080.1 - 8.8e-56 189.2 0.0 1.1e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95080.1 - 4.6e-26 91.6 0.0 6.1e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX95080.1 - 2.2e-05 23.9 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX95080.1 - 0.00077 18.9 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX95080.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX95080.1 - 0.006 15.4 0.0 0.0086 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX95080.1 - 0.011 14.7 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 ORX95080.1 - 0.09 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 ORX95080.1 - 0.099 12.2 0.6 0.18 11.4 0.1 1.5 2 0 0 2 2 2 0 RIO1 family Trypsin PF00089.26 ORX95081.1 - 1.1e-26 94.0 0.0 1.2e-26 93.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX95081.1 - 7.5e-06 26.9 0.0 9.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Noelin-1 PF12308.8 ORX95081.1 - 0.026 14.5 0.2 0.1 12.6 0.1 2.0 1 1 1 2 2 2 0 Neurogenesis glycoprotein RuvA_C PF07499.13 ORX95081.1 - 0.076 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 RuvA, C-terminal domain Sec2p PF06428.11 ORX95082.1 - 4.1e-18 65.1 12.6 4.1e-18 65.1 12.6 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 ORX95082.1 - 0.0015 17.2 16.5 0.002 16.8 16.5 1.2 1 0 0 1 1 1 1 Macoilin family DUF4718 PF15842.5 ORX95082.1 - 0.0031 17.3 0.5 0.0088 15.9 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4718) TRPM_tetra PF16519.5 ORX95082.1 - 7.5 6.7 17.7 0.92 9.7 3.6 4.5 6 0 0 6 6 6 0 Tetramerisation domain of TRPM Pkinase PF00069.25 ORX95084.1 - 1.2e-55 188.8 0.0 2e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95084.1 - 9.7e-41 139.8 0.0 1.5e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORX95084.1 - 0.00055 20.1 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 ORX95084.1 - 0.011 14.5 0.0 0.049 12.4 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase DUF3560 PF12083.8 ORX95084.1 - 0.066 13.3 2.2 0.13 12.4 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Imm30 PF15565.6 ORX95084.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 30 zf-C2H2 PF00096.26 ORX95085.1 - 3.6e-12 46.0 9.9 9.6e-07 28.9 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX95085.1 - 1e-07 32.0 5.9 6.8e-07 29.4 1.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX95085.1 - 7.6e-06 26.3 8.5 0.0012 19.5 1.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95085.1 - 0.0097 16.2 1.9 0.12 12.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX95085.1 - 0.071 13.1 0.6 0.071 13.1 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Ogr_Delta PF04606.12 ORX95085.1 - 0.14 12.1 1.6 1.7 8.7 1.5 2.3 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 ORX95085.1 - 1.6 8.6 7.3 5.6 6.8 1.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORX95085.1 - 2 8.4 4.9 11 6.0 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 ORX95087.1 - 2.8e-12 46.5 11.1 5e-07 29.8 2.0 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX95087.1 - 9.6e-12 44.7 12.3 1.7e-05 25.0 4.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95087.1 - 7e-07 29.6 16.5 0.00041 20.9 3.5 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95087.1 - 0.00027 21.1 3.4 0.07 13.4 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX95087.1 - 0.0051 17.1 1.2 0.01 16.1 1.2 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 ORX95087.1 - 0.042 13.5 1.0 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 ORX95087.1 - 0.055 13.2 11.4 4.1 7.2 6.2 3.5 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORX95087.1 - 0.25 11.4 8.3 0.77 9.8 1.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.12 ORX95087.1 - 0.38 11.5 4.2 0.26 12.1 1.9 1.9 1 1 1 2 2 2 0 CHORD Glyco_transf_8 PF01501.20 ORX95088.1 - 3e-21 76.2 0.6 3.7e-21 75.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORX95088.1 - 2.3e-05 23.9 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORX95088.1 - 0.00046 20.2 5.6 0.0016 18.4 5.6 1.7 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Homeodomain PF00046.29 ORX95089.1 - 1.4e-20 72.8 0.6 1.6e-20 72.7 0.6 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX95089.1 - 0.00023 21.0 0.1 0.0003 20.6 0.1 1.2 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX95089.1 - 0.063 13.1 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT UPF0154 PF03672.13 ORX95089.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) adh_short PF00106.25 ORX95111.1 - 3.5e-20 72.3 0.0 6.3e-19 68.2 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX95111.1 - 1.9e-10 40.7 0.0 2e-06 27.5 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX95111.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Uds1 PF15456.6 ORX95112.1 - 7.6e-18 64.9 7.1 7.6e-18 64.9 7.1 3.3 3 0 0 3 3 3 1 Up-regulated During Septation HR1 PF02185.16 ORX95112.1 - 2.9e-08 33.7 5.7 2.9e-08 33.7 5.7 2.4 2 0 0 2 2 2 1 Hr1 repeat GIT_CC PF16559.5 ORX95112.1 - 0.0008 19.2 16.4 0.11 12.4 0.6 4.4 4 0 0 4 4 4 2 GIT coiled-coil Rho guanine nucleotide exchange factor YopE_N PF09020.10 ORX95112.1 - 0.013 15.7 3.5 0.03 14.6 0.8 2.6 2 1 1 3 3 3 0 YopE, N terminal SOGA PF11365.8 ORX95112.1 - 0.095 13.8 9.1 0.91 10.7 1.6 3.0 2 0 0 2 2 2 0 Protein SOGA Rootletin PF15035.6 ORX95112.1 - 0.24 11.4 14.7 0.16 12.0 4.5 2.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 ORX95112.1 - 0.24 11.9 0.2 0.24 11.9 0.2 4.1 3 1 0 3 3 2 0 Cell division protein ZapB UPF0242 PF06785.11 ORX95112.1 - 0.29 11.2 17.0 0.071 13.2 4.2 3.1 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 ORX95112.1 - 0.37 9.6 10.5 1.9 7.3 2.7 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 ORX95112.1 - 0.51 9.9 16.5 0.19 11.3 2.7 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 ORX95112.1 - 0.76 10.1 3.3 4.8 7.5 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 ORX95112.1 - 1 9.4 13.0 2.2 8.2 2.4 3.1 3 0 0 3 3 3 0 Prefoldin subunit LPP PF04728.13 ORX95112.1 - 1.1 9.7 6.7 68 4.0 0.0 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF4795 PF16043.5 ORX95112.1 - 1.3 8.6 9.5 0.77 9.3 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) WDCP PF15390.6 ORX95112.1 - 2.3 6.5 11.4 0.069 11.5 3.9 2.0 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Occludin_ELL PF07303.13 ORX95112.1 - 2.7 8.8 7.7 1.4 9.7 0.8 3.4 2 1 0 2 2 2 0 Occludin homology domain CLZ PF16526.5 ORX95112.1 - 3.8 7.9 9.6 0.84 10.0 1.4 3.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 ORX95112.1 - 4.4 7.5 9.3 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 ORX95112.1 - 5.4 6.9 14.8 9.3 6.1 0.1 4.3 4 0 0 4 4 4 0 Septum formation initiator FAM76 PF16046.5 ORX95112.1 - 6 6.1 9.9 4.8 6.5 0.8 2.6 2 0 0 2 2 2 0 FAM76 protein Seryl_tRNA_N PF02403.22 ORX95112.1 - 6 7.1 12.4 7.4 6.9 0.4 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 ORX95112.1 - 6.5 5.2 5.5 12 4.3 0.7 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A NRBF2 PF08961.10 ORX95112.1 - 9.7 5.7 16.7 3.8 7.1 3.8 3.0 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Tom7 PF08038.12 ORX95113.1 - 8.7e-17 60.5 0.3 9.6e-17 60.4 0.3 1.0 1 0 0 1 1 1 1 TOM7 family Arf PF00025.21 ORX95115.1 - 3.7e-80 267.5 0.1 4.2e-80 267.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX95115.1 - 2.7e-14 53.4 0.0 3.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORX95115.1 - 5.4e-14 52.0 0.0 6.6e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORX95115.1 - 3.5e-13 49.5 1.2 2.4e-09 36.8 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORX95115.1 - 6.2e-13 48.7 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX95115.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX95115.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX95115.1 - 0.0066 15.8 0.5 0.021 14.1 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Uds1 PF15456.6 ORX95116.1 - 1.1e-09 38.6 1.3 1.1e-09 38.6 1.3 4.1 4 1 0 4 4 4 1 Up-regulated During Septation HR1 PF02185.16 ORX95116.1 - 0.00013 22.0 0.8 0.00013 22.0 0.8 4.3 4 1 0 4 4 4 1 Hr1 repeat ERM PF00769.19 ORX95116.1 - 0.0021 17.9 14.8 0.0021 17.9 14.8 2.5 2 2 0 2 2 2 1 Ezrin/radixin/moesin family Cortex-I_coil PF09304.10 ORX95116.1 - 0.0045 17.2 5.6 0.0045 17.2 5.6 2.6 4 0 0 4 4 2 1 Cortexillin I, coiled coil DUF4094 PF13334.6 ORX95116.1 - 0.0055 17.1 1.8 2.4 8.6 0.0 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4094) ZapB PF06005.12 ORX95116.1 - 0.023 15.1 17.8 1.9 9.0 0.6 5.0 4 2 0 4 4 4 0 Cell division protein ZapB Ago_N_1 PF18351.1 ORX95116.1 - 0.041 14.3 0.4 5.6 7.5 0.1 3.4 2 1 1 3 3 3 0 Fungal Argonaute N-terminal domain D5_N PF08706.11 ORX95116.1 - 0.075 13.3 1.1 0.29 11.4 0.4 2.3 2 1 0 2 2 2 0 D5 N terminal like NICE-3 PF07406.11 ORX95116.1 - 0.081 12.9 0.2 0.26 11.3 0.2 1.9 1 0 0 1 1 1 0 NICE-3 protein LPP PF04728.13 ORX95116.1 - 0.099 13.0 9.2 2.9 8.4 0.1 4.7 4 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 ORX95116.1 - 0.27 10.5 10.9 1.2 8.4 10.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 ORX95116.1 - 0.3 9.7 0.8 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) YgaB PF14182.6 ORX95116.1 - 0.47 10.9 0.1 0.47 10.9 0.1 3.7 5 0 0 5 5 3 0 YgaB-like protein BMFP PF04380.13 ORX95116.1 - 0.63 10.6 8.2 0.89 10.1 0.7 3.7 4 0 0 4 4 3 0 Membrane fusogenic activity Atg14 PF10186.9 ORX95116.1 - 0.67 9.0 16.2 1 8.4 0.9 3.1 3 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR19-TM PF15176.6 ORX95116.1 - 0.96 9.5 3.5 25 4.9 0.1 3.2 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF5320 PF17253.2 ORX95116.1 - 1.7 9.8 3.4 30 5.8 0.1 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5320) PhaP_Bmeg PF09602.10 ORX95116.1 - 1.8 8.4 13.1 1.1 9.1 1.2 3.1 3 1 1 4 4 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FapA PF03961.13 ORX95116.1 - 3.3 6.2 10.3 3.5 6.1 6.7 2.4 2 1 1 3 3 3 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 ORX95116.1 - 3.6 8.0 13.0 2.5 8.6 0.4 4.8 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF1465 PF07323.12 ORX95116.1 - 4.3 7.2 9.4 1.8 8.4 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1465) YabA PF06156.13 ORX95116.1 - 4.9 7.8 18.9 5.4 7.7 1.0 4.6 3 1 2 5 5 5 0 Initiation control protein YabA FlxA PF14282.6 ORX95116.1 - 6.1 6.9 12.6 1.4 9.0 0.7 3.8 3 1 1 4 4 3 0 FlxA-like protein CENP-F_leu_zip PF10473.9 ORX95116.1 - 6.1 6.9 29.0 0.25 11.3 8.1 4.6 5 0 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 ORX95116.1 - 6.7 6.7 11.7 18 5.4 0.1 3.3 2 2 1 3 3 3 0 Laminin Domain II PRKG1_interact PF15898.5 ORX95116.1 - 7.9 7.4 23.5 2.3e+02 2.7 0.2 4.5 4 1 0 4 4 3 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 ORX95116.1 - 8.1 6.8 17.4 1.3 9.3 0.6 4.4 4 0 0 4 4 4 0 TSC-22/dip/bun family UCH PF00443.29 ORX95117.1 - 3.1e-15 56.4 0.0 6.6e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX95117.1 - 8.9e-05 22.2 0.0 0.05 13.2 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PHM7_ext PF12621.8 ORX95117.1 - 0.11 12.6 0.0 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter DIOX_N PF14226.6 ORX95118.1 - 1.5e-21 77.3 0.0 2.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORX95118.1 - 6.8e-17 61.8 0.1 1.2e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CAP PF00188.26 ORX95119.1 - 3.5e-18 66.7 0.2 4.3e-18 66.3 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cyclin PF08613.11 ORX95121.1 - 1.5e-19 70.9 0.9 2e-19 70.5 0.9 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX95121.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_15 PF00723.21 ORX95124.1 - 7.4e-144 479.9 0.0 9e-144 479.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 ORX95124.1 - 2.5e-23 82.4 0.0 6.1e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Interleukin-like EMT inducer YkuD PF03734.14 ORX95124.1 - 0.16 12.4 0.1 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 L,D-transpeptidase catalytic domain E1-E2_ATPase PF00122.20 ORX95125.1 - 1.4e-47 161.6 1.8 1.4e-47 161.6 1.8 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX95125.1 - 4.7e-31 107.9 3.0 4.7e-31 107.9 3.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX95125.1 - 3.3e-20 71.9 0.0 6.9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX95125.1 - 4.1e-18 66.5 0.0 9.2e-15 55.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX95125.1 - 1.5e-14 53.4 0.0 4.1e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX95125.1 - 0.00024 20.9 0.9 0.0035 17.1 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ERGIC_N PF13850.6 ORX95125.1 - 0.18 12.2 0.4 0.63 10.4 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ATP11 PF06644.11 ORX95126.1 - 2.5e-77 260.4 2.0 2.9e-77 260.1 2.0 1.0 1 0 0 1 1 1 1 ATP11 protein FAD_binding_3 PF01494.19 ORX95127.1 - 6.3e-72 242.7 0.0 7.6e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ORX95127.1 - 4.8e-07 29.1 0.0 1.8e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase fn3 PF00041.21 ORX95128.1 - 6.5e-05 23.2 0.5 0.00021 21.6 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III domain ATG16 PF08614.11 ORX95128.1 - 0.0013 19.0 17.1 0.0013 19.0 17.1 2.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) KaiA PF07688.12 ORX95128.1 - 0.29 11.3 2.1 0.63 10.2 2.1 1.5 1 0 0 1 1 1 0 KaiA C-terminal domain Homeodomain PF00046.29 ORX95151.1 - 1.5e-17 63.2 2.4 1.6e-17 63.1 2.4 1.0 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 ORX95151.1 - 0.0023 17.8 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 ORX95151.1 - 0.0088 15.9 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 ORX95151.1 - 0.015 15.1 0.0 0.058 13.2 0.0 1.8 1 1 1 2 2 2 0 Homeodomain-like domain RQC PF09382.10 ORX95152.1 - 2.3e-23 82.2 0.5 7.5e-23 80.5 0.5 2.0 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 ORX95152.1 - 2.7e-22 79.4 0.0 7.8e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX95152.1 - 8.8e-21 74.3 0.2 9.4e-19 67.8 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORX95152.1 - 1.2e-17 64.3 6.7 5.8e-17 62.2 6.7 2.3 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 ORX95152.1 - 1.7e-13 50.3 0.0 3.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 ORX95152.1 - 6e-06 26.4 0.1 3.4e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HHH PF00633.23 ORX95152.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif PPR_2 PF13041.6 ORX95153.1 - 1.9e-198 642.7 55.0 1.6e-17 63.4 0.5 23.2 4 2 18 23 23 23 23 PPR repeat family PPR PF01535.20 ORX95153.1 - 6.9e-147 467.9 32.4 6.5e-08 32.3 0.2 27.0 27 0 0 27 27 27 22 PPR repeat PPR_1 PF12854.7 ORX95153.1 - 4.9e-145 470.8 8.1 6.2e-09 35.4 0.0 26.3 26 0 0 26 26 26 22 PPR repeat PPR_3 PF13812.6 ORX95153.1 - 7.7e-131 426.3 34.9 9.8e-14 51.2 0.1 15.9 9 6 6 17 17 17 15 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX95153.1 - 3.5e-68 229.2 16.7 1.2e-12 47.7 0.1 9.7 1 1 7 8 8 8 8 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX95153.1 - 4.9e-16 59.2 31.8 0.037 14.4 0.2 14.0 6 4 8 14 14 14 3 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORX95153.1 - 1.1e-14 53.8 0.0 0.22 12.4 0.0 14.4 12 4 6 18 18 15 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX95153.1 - 1.5e-11 44.6 7.4 0.0096 16.4 0.1 10.1 10 3 3 14 14 12 1 Tetratricopeptide repeat ATP13 PF12921.7 ORX95153.1 - 2.1e-10 40.5 17.4 0.13 12.1 0.4 10.8 5 4 7 12 12 12 2 Mitochondrial ATPase expression Vps39_1 PF10366.9 ORX95153.1 - 8e-07 29.3 6.9 6.2 7.1 0.1 8.6 7 2 1 8 8 8 1 Vacuolar sorting protein 39 domain 1 MRP-S27 PF10037.9 ORX95153.1 - 9.3e-07 28.0 11.1 0.1 11.4 0.0 8.0 5 3 4 9 9 9 3 Mitochondrial 28S ribosomal protein S27 AEP1 PF17049.5 ORX95153.1 - 4.7e-05 22.7 15.3 2.2 7.3 0.1 8.1 3 3 5 9 9 9 1 ATPase expression protein 1 ECSIT PF06239.11 ORX95153.1 - 0.00044 19.4 5.0 0.51 9.4 0.0 6.8 5 3 4 9 9 9 1 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.20 ORX95153.1 - 0.0041 17.0 13.1 0.19 11.6 0.0 6.3 7 1 0 8 8 7 1 Region in Clathrin and VPS B12-binding_2 PF02607.17 ORX95153.1 - 0.04 14.4 0.1 81 3.8 0.0 4.4 4 0 0 4 4 3 0 B12 binding domain DUF3368 PF11848.8 ORX95153.1 - 0.062 13.1 0.2 6.2 6.7 0.0 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF3368) Wzy_C_2 PF11846.8 ORX95153.1 - 0.063 13.2 2.7 12 5.7 0.0 5.3 6 2 0 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal Prp18 PF02840.15 ORX95153.1 - 2.2 8.3 10.5 1.2e+02 2.7 0.1 6.3 5 2 3 8 8 8 0 Prp18 domain UPF0014 PF03649.13 ORX95154.1 - 3.4e-66 223.0 14.4 4.1e-66 222.8 14.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Cyclin PF08613.11 ORX95155.1 - 1.4e-12 48.3 0.1 1.7e-12 48.0 0.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX95155.1 - 1.8e-09 37.4 0.2 2.1e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain NgoMIV_restric PF09015.10 ORX95155.1 - 0.024 13.8 0.0 0.027 13.6 0.0 1.0 1 0 0 1 1 1 0 NgoMIV restriction enzyme 6PF2K PF01591.18 ORX95155.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Fasciclin PF02469.22 ORX95156.1 - 2.8e-33 114.9 0.3 1.8e-17 63.8 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain DUF4037 PF13228.6 ORX95156.1 - 0.09 13.6 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) SRPRB PF09439.10 ORX95157.1 - 1.5e-41 141.9 0.0 2.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 ORX95157.1 - 7.4e-17 61.3 0.0 1.5e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX95157.1 - 5e-05 22.8 0.0 8.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX95157.1 - 0.00069 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORX95157.1 - 0.00071 19.6 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORX95157.1 - 0.001 18.3 0.1 0.63 9.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 ORX95157.1 - 0.0021 17.6 0.3 0.014 14.9 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DEAD PF00270.29 ORX95158.1 - 2e-46 158.0 0.0 3.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX95158.1 - 9.1e-26 90.4 0.0 5.3e-25 87.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORX95158.1 - 2.4e-19 69.3 0.5 4.4e-19 68.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORX95158.1 - 3.8e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORX95158.1 - 0.076 13.3 0.3 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RhoGAP PF00620.27 ORX95159.1 - 1.4e-43 148.3 1.9 2.3e-43 147.6 0.0 2.3 3 1 1 4 4 4 1 RhoGAP domain FCH PF00611.23 ORX95159.1 - 1.5e-07 31.5 0.2 1.5e-07 31.5 0.2 2.3 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2852 PF11014.8 ORX95159.1 - 0.038 14.1 9.2 2.1 8.5 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2852) HAUS4 PF14735.6 ORX95159.1 - 0.04 13.6 7.2 0.043 13.5 5.5 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF1216 PF06746.11 ORX95159.1 - 0.89 9.6 10.2 5.7 6.9 2.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) Sec7 PF01369.20 ORX95160.1 - 1e-69 233.9 3.1 1.1e-69 233.8 0.9 2.4 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 ORX95160.1 - 5.8e-41 140.0 4.5 5.8e-41 140.0 4.5 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORX95160.1 - 5.4e-37 125.5 15.8 1.5e-35 120.9 1.0 6.3 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 ORX95160.1 - 5.8e-24 84.7 6.4 1.2e-21 77.2 0.0 5.5 4 2 1 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 ORX95160.1 - 0.064 13.3 0.5 14 5.8 0.0 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) MT-A70 PF05063.14 ORX95161.1 - 1.3e-15 57.7 0.1 2.2e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 MT-A70 RAC_head PF16717.5 ORX95161.1 - 0.041 14.9 0.9 0.1 13.6 0.7 1.8 1 1 0 1 1 1 0 Ribosome-associated complex head domain Lge1 PF11488.8 ORX95161.1 - 0.046 13.9 0.2 0.046 13.9 0.2 1.9 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Acetyltransf_10 PF13673.7 ORX95162.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX95162.1 - 0.0011 19.3 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX95162.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DFRP_C PF16543.5 ORX95163.1 - 4.6e-27 94.3 0.4 4.6e-27 94.3 0.4 3.8 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 ORX95163.1 - 1.7e-05 24.6 1.6 1.7e-05 24.6 1.6 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX95163.1 - 0.00057 19.6 9.5 0.03 14.1 1.4 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 ORX95163.1 - 0.0019 18.8 18.8 0.011 16.5 7.7 3.7 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 ORX95163.1 - 0.0076 16.3 7.6 0.0076 16.3 7.6 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 ORX95163.1 - 0.099 12.9 5.6 1.6 9.0 0.7 3.0 1 1 0 2 2 2 0 Zinc-finger containing family UPF0240 PF06784.11 ORX95163.1 - 0.12 12.5 11.0 1 9.4 5.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) zf-CCCH_2 PF14608.6 ORX95163.1 - 0.69 10.5 14.1 0.093 13.2 2.9 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Kinesin PF00225.23 ORX95164.1 - 1.8e-100 336.1 0.2 5.2e-100 334.6 0.2 1.8 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX95164.1 - 1.7e-12 47.5 0.0 5.1e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF3196 PF11428.8 ORX95164.1 - 0.00073 19.2 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3196) DUF4349 PF14257.6 ORX95164.1 - 0.0037 16.8 1.7 0.0075 15.7 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Med22 PF06179.12 ORX95164.1 - 0.012 15.8 0.4 0.051 13.8 0.4 2.0 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex CALCOCO1 PF07888.11 ORX95164.1 - 0.16 10.8 7.2 0.28 10.0 7.2 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Arrestin_C PF02752.22 ORX95165.1 - 1.1e-11 45.3 0.6 3.6e-08 33.9 0.2 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX95165.1 - 3.4e-06 27.2 0.4 0.00016 21.7 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_U57 PF05582.12 ORX95165.1 - 0.0051 16.1 0.0 0.0069 15.7 0.0 1.1 1 0 0 1 1 1 1 YabG peptidase U57 ELFV_dehydrog PF00208.21 ORX95165.1 - 0.058 13.1 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase VHL PF01847.16 ORX95165.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain Mem_trans PF03547.18 ORX95166.1 - 4.9e-24 84.5 7.3 6.2e-24 84.1 7.3 1.1 1 0 0 1 1 1 1 Membrane transport protein RabGAP-TBC PF00566.18 ORX95167.1 - 1.7e-12 47.5 0.7 2e-12 47.2 0.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MCM3AP_GANP PF16769.5 ORX95167.1 - 0.035 12.4 0.0 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP ANAPC4_WD40 PF12894.7 ORX95168.1 - 0.005 17.1 0.5 0.23 11.8 0.1 2.8 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Brucella_OMP2 PF05244.11 ORX95168.1 - 0.0098 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Brucella outer membrane protein 2 ICAP-1_inte_bdg PF10480.9 ORX95168.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-1 integrin binding protein WD40 PF00400.32 ORX95168.1 - 0.048 14.5 0.5 3.7 8.6 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat CDP-OH_P_transf PF01066.21 ORX95169.1 - 8.5e-12 45.7 0.3 8.5e-12 45.7 0.3 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase XFP_N PF09364.10 ORX95170.1 - 3.3e-153 509.8 0.1 4.2e-153 509.5 0.1 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 ORX95170.1 - 4.4e-79 264.3 0.0 2.7e-78 261.7 0.0 2.0 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 ORX95170.1 - 8.4e-79 263.7 0.0 1.3e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 ORX95170.1 - 0.0069 16.2 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Sugar_tr PF00083.24 ORX95171.1 - 2.1e-58 198.3 23.8 2.6e-58 198.0 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX95171.1 - 3.9e-27 95.1 26.1 1e-26 93.7 24.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX95171.1 - 8.9e-07 28.5 2.1 1.9e-06 27.4 2.1 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX95171.1 - 0.00011 20.9 8.0 0.00011 20.9 8.0 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORX95171.1 - 0.004 16.7 0.9 0.049 13.2 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORX95171.1 - 0.17 10.1 9.3 0.054 11.8 3.5 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_FMN PF00724.20 ORX95172.1 - 1.1e-95 320.8 0.0 1.3e-95 320.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PHD PF00628.29 ORX95181.1 - 5.8e-11 42.1 5.3 5.8e-11 42.1 5.3 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 ORX95181.1 - 1.6e-05 24.3 2.5 7.3e-05 22.2 0.5 2.3 2 0 0 2 2 2 1 PHD-finger Rubredoxin PF00301.20 ORX95181.1 - 0.043 13.9 2.7 0.95 9.5 0.1 3.0 2 0 0 2 2 2 0 Rubredoxin PHD_4 PF16866.5 ORX95181.1 - 7.8 6.7 9.2 23 5.2 9.2 1.8 1 1 0 1 1 1 0 PHD-finger Cullin_binding PF03556.15 ORX95182.1 - 2.4e-38 131.3 0.6 2.9e-38 131.0 0.6 1.1 1 0 0 1 1 1 1 Cullin binding AKAP28 PF14469.6 ORX95182.1 - 0.06 13.1 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 28 kDa A-kinase anchor DUF2829 PF11195.8 ORX95182.1 - 0.12 12.7 0.0 8.3 6.7 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2829) DUF3384 PF11864.8 ORX95182.1 - 0.12 11.2 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) UBA_4 PF14555.6 ORX95183.1 - 6.1e-12 45.2 0.1 7.7e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.31 ORX95183.1 - 0.023 14.6 0.4 0.048 13.6 0.1 1.6 2 0 0 2 2 2 0 UBA/TS-N domain DUF2937 PF11157.8 ORX95183.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Ribosomal_S7 PF00177.21 ORX95184.1 - 1.3e-37 128.7 0.7 1.6e-37 128.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Chitin_synth_2 PF03142.15 ORX95185.1 - 1.9e-233 775.9 0.9 3.3e-233 775.1 0.9 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX95185.1 - 2.5e-14 53.7 6.4 9.3e-14 51.8 6.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX95185.1 - 5.3e-12 46.1 0.0 2e-11 44.2 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX95185.1 - 9.7e-05 21.9 0.1 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX95185.1 - 0.00093 19.0 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 SBF2 PF12335.8 ORX95186.1 - 0.0093 15.6 2.4 0.011 15.4 2.4 1.0 1 0 0 1 1 1 1 Myotubularin protein Pex2_Pex12 PF04757.14 ORX95187.1 - 1.4e-40 139.3 8.0 1.7e-40 139.0 8.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 ORX95187.1 - 1.1e-09 38.0 12.5 1.6e-09 37.5 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX95187.1 - 7.3e-08 32.6 18.3 1.4e-07 31.7 18.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX95187.1 - 2.1e-06 27.5 16.7 3.5e-06 26.8 16.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX95187.1 - 5.1e-06 26.2 17.0 8.9e-06 25.5 17.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX95187.1 - 2.8e-05 23.9 14.0 4.7e-05 23.2 14.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORX95187.1 - 0.00014 22.1 12.4 0.00028 21.1 12.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORX95187.1 - 0.00076 19.4 14.1 0.0013 18.6 14.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX95187.1 - 0.0057 16.7 11.0 0.0057 16.7 11.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Cas_Csn2 PF09711.10 ORX95187.1 - 0.0082 15.8 0.1 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Csn2) zf-C4H2 PF10146.9 ORX95187.1 - 0.095 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein U-box PF04564.15 ORX95187.1 - 0.13 12.4 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-C3HC4_4 PF15227.6 ORX95187.1 - 0.21 11.8 14.7 0.53 10.5 14.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORX95187.1 - 0.43 10.7 6.6 1.1 9.3 6.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 ORX95187.1 - 2.3 8.4 10.4 5.5 7.2 10.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ribosomal_L34 PF00468.17 ORX95188.1 - 4.5e-21 74.5 6.4 7.9e-21 73.8 6.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 NHL PF01436.21 ORX95189.1 - 2.7e-05 23.9 0.0 0.58 10.3 0.0 3.5 3 0 0 3 3 3 2 NHL repeat GSDH PF07995.11 ORX95189.1 - 0.0035 16.7 0.2 0.011 15.1 0.1 1.8 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Chitin_synth_1 PF01644.17 ORX95190.1 - 1.2e-73 246.5 0.1 1.8e-73 245.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORX95190.1 - 9.9e-27 92.7 0.1 1.8e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORX95190.1 - 1.1e-26 93.5 1.9 1.1e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX95190.1 - 3.2e-09 37.0 0.3 3.2e-09 37.0 0.3 3.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX95190.1 - 0.00092 19.2 0.0 0.0056 16.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 TniB PF05621.11 ORX95190.1 - 0.22 10.9 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Cyclin PF08613.11 ORX95191.1 - 9.1e-08 32.6 0.0 1.1e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX95191.1 - 3.8e-07 29.9 0.0 5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Trimer_CC PF08954.11 ORX95191.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif VID27 PF08553.10 ORX95192.1 - 6.2e-170 565.0 0.7 6.2e-170 565.0 0.7 1.8 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 ORX95192.1 - 5.7e-53 179.3 1.5 5.7e-53 179.3 1.5 3.5 2 1 1 3 3 3 2 VID27 N-terminal region VID27_PH PF17747.1 ORX95192.1 - 2.7e-31 108.1 4.4 8.4e-31 106.5 0.4 2.8 2 1 0 2 2 2 1 VID27 PH-like domain YL1 PF05764.13 ORX95192.1 - 0.011 15.9 9.6 0.022 14.9 9.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Rpp20 PF12328.8 ORX95192.1 - 0.059 13.3 2.8 0.12 12.3 2.8 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P CDC45 PF02724.14 ORX95192.1 - 1.8 6.7 8.3 2.8 6.1 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ORX95192.1 - 5.8 6.1 11.0 13 5.0 11.0 1.5 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ORX95192.1 - 9.3 4.2 14.7 14 3.6 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi LPMO_10 PF03067.15 ORX95193.1 - 2.1e-05 25.3 0.2 5.3e-05 24.0 0.0 1.6 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX95193.1 - 0.021 14.7 0.3 0.82 9.6 0.3 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 HSP70 PF00012.20 ORX95194.1 - 2.5e-50 171.3 1.7 2.9e-50 171.1 1.7 1.0 1 0 0 1 1 1 1 Hsp70 protein Transferase PF02458.15 ORX95196.1 - 4.5e-22 78.3 0.0 8.7e-22 77.4 0.0 1.4 2 0 0 2 2 2 1 Transferase family FAD_binding_4 PF01565.23 ORX95197.1 - 1.8e-29 102.2 1.8 3.5e-29 101.3 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX95197.1 - 2.6e-16 59.4 5.4 2.6e-16 59.4 5.4 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 ORX95197.1 - 0.013 15.0 0.3 0.02 14.3 0.3 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RPN6_N PF18055.1 ORX95197.1 - 0.18 12.1 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain CreA PF05981.12 ORX95198.1 - 0.11 12.5 0.2 1.5 8.8 0.0 2.1 1 1 1 2 2 2 0 CreA protein DUF4681 PF15732.5 ORX95198.1 - 0.14 12.4 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4681) Acetyltransf_5 PF13444.6 ORX95199.1 - 8.7e-08 32.8 0.0 1.3e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX95199.1 - 6.2e-05 22.9 0.0 0.00084 19.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX95199.1 - 6.5e-05 23.1 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORX95199.1 - 0.0001 22.4 0.0 0.0097 16.0 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Xan_ur_permease PF00860.20 ORX95220.1 - 1.1e-63 215.3 33.0 3e-62 210.6 33.0 2.1 1 1 0 1 1 1 1 Permease family ABC_tran PF00005.27 ORX95221.1 - 5.4e-25 88.5 0.0 1.2e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX95221.1 - 1e-19 70.9 22.2 1.4e-19 70.4 22.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX95221.1 - 6.4e-07 29.5 0.1 0.0006 19.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORX95221.1 - 0.065 13.6 0.0 0.3 11.4 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORX95221.1 - 0.12 12.9 0.6 0.91 9.9 0.6 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Holin_BhlA PF10960.8 ORX95221.1 - 2.4 8.2 4.5 11 6.0 0.0 3.1 3 0 0 3 3 3 0 BhlA holin family Cys_Met_Meta_PP PF01053.20 ORX95222.1 - 7.3e-156 518.5 0.3 8.2e-156 518.3 0.3 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORX95222.1 - 6.2e-08 32.0 0.4 1.2e-07 31.0 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORX95222.1 - 4.6e-06 26.0 0.0 6.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORX95222.1 - 0.00091 18.6 1.3 0.0013 18.1 0.3 1.8 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 ORX95222.1 - 0.034 13.0 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Allinase Mannosyl_trans2 PF04188.13 ORX95224.1 - 5.3e-86 289.7 30.7 6.7e-86 289.3 30.7 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) INCENP_ARK-bind PF03941.15 ORX95225.1 - 6.7e-21 74.0 1.7 1e-20 73.4 1.7 1.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ThrE PF06738.12 ORX95226.1 - 1.2e-61 208.2 12.8 4e-54 183.5 1.3 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORX95226.1 - 2e-10 40.9 18.4 4.8e-09 36.4 5.9 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Cornichon PF03311.14 ORX95226.1 - 0.36 11.2 3.3 0.22 11.8 0.9 1.9 2 0 0 2 2 2 0 Cornichon protein GFO_IDH_MocA PF01408.22 ORX95227.1 - 5.5e-19 69.2 0.0 8.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX95227.1 - 1.9e-11 44.0 0.0 4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 ORX95227.1 - 0.025 15.2 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ribonuc_red_sm PF00268.21 ORX95228.1 - 1.2e-121 405.5 0.2 1.5e-121 405.2 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain WD40 PF00400.32 ORX95229.1 - 1.2e-10 41.8 3.8 1.7e-06 28.6 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX95229.1 - 5e-06 26.7 0.9 0.12 12.7 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX95229.1 - 0.055 12.1 0.0 0.088 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ORX95229.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain tRNA-synt_2 PF00152.20 ORX95230.1 - 1.8e-93 313.1 0.0 2.1e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORX95230.1 - 1.8e-10 40.7 0.3 3.3e-10 39.8 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LSM PF01423.22 ORX95231.1 - 4.9e-19 67.8 1.7 6.5e-19 67.4 1.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORX95231.1 - 0.0093 16.1 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 ORX95231.1 - 0.011 15.7 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 ORX95231.1 - 0.041 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) PLU-1 PF08429.11 ORX95233.1 - 4.5e-55 187.2 5.7 2.2e-50 171.8 3.8 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 ORX95233.1 - 6.4e-31 107.1 0.1 1.7e-30 105.8 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 ORX95233.1 - 2.2e-20 72.3 22.1 2e-13 50.0 5.5 3.1 3 0 0 3 3 3 2 PHD-finger ARID PF01388.21 ORX95233.1 - 5.4e-18 65.4 0.1 7.1e-17 61.9 0.0 2.7 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 ORX95233.1 - 1.4e-14 53.7 2.7 3.7e-14 52.4 2.7 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 ORX95233.1 - 1.1e-05 25.8 9.7 0.001 19.4 9.7 3.3 1 1 0 1 1 1 1 C5HC2 zinc finger Hydrolase_3 PF08282.12 ORX95233.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-PHD-like PF15446.6 ORX95233.1 - 1.9 8.1 17.1 0.046 13.3 0.9 3.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain HLH PF00010.26 ORX95235.1 - 8.1e-14 51.3 0.9 8.1e-14 51.3 0.9 2.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 ORX95235.1 - 0.00033 20.7 4.3 0.00033 20.7 4.3 1.8 1 1 0 1 1 1 1 TolA binding protein trimerisation HALZ PF02183.18 ORX95235.1 - 0.0043 17.2 1.4 0.0043 17.2 1.4 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 ORX95235.1 - 0.0043 17.1 3.1 0.0043 17.1 3.1 2.4 2 1 0 2 2 2 1 bZIP transcription factor Cep57_MT_bd PF06657.13 ORX95235.1 - 0.029 14.8 5.7 0.053 14.0 1.1 2.3 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3450 PF11932.8 ORX95235.1 - 0.032 13.5 6.8 0.024 14.0 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) LPP PF04728.13 ORX95235.1 - 0.043 14.2 0.9 0.043 14.2 0.9 1.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper APC_N_CC PF16689.5 ORX95235.1 - 0.062 13.4 1.9 0.062 13.4 1.9 2.3 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain FlaC_arch PF05377.11 ORX95235.1 - 0.077 13.4 3.1 0.084 13.3 1.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_A30L_A26L PF06086.12 ORX95235.1 - 0.078 12.7 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein TSC22 PF01166.18 ORX95235.1 - 0.1 13.0 4.7 0.12 12.7 1.2 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family MctB PF11382.8 ORX95235.1 - 0.17 11.5 1.6 0.25 11.0 1.6 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Spc7 PF08317.11 ORX95235.1 - 0.2 10.5 9.5 0.22 10.4 9.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 ORX95235.1 - 0.57 10.4 9.2 1.9 8.7 4.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 ORX95235.1 - 1.1 9.1 7.5 0.61 9.9 5.0 1.9 1 1 1 2 2 2 0 Septum formation initiator betaPIX_CC PF16523.5 ORX95235.1 - 1.7 8.5 7.6 0.12 12.2 2.0 1.8 2 0 0 2 2 2 0 betaPIX coiled coil DUF3886 PF13025.6 ORX95235.1 - 4.9 7.4 14.6 1.2 9.3 6.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) ZapB PF06005.12 ORX95235.1 - 5.4 7.5 14.0 0.28 11.7 6.2 2.4 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 ORX95235.1 - 5.5 7.7 8.1 3.5 8.3 4.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA GPI-anchored PF10342.9 ORX95236.1 - 2.2e-06 28.4 0.1 3.2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4609 PF15382.6 ORX95236.1 - 0.22 11.4 0.7 0.4 10.6 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4609) Arrestin_N PF00339.29 ORX95237.1 - 0.0016 18.5 0.1 0.0047 17.0 0.1 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Methyltransf_11 PF08241.12 ORX95238.1 - 1.4e-22 80.2 0.0 2.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX95238.1 - 3.5e-21 75.7 0.0 5.6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX95238.1 - 6e-17 62.1 0.0 1.1e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95238.1 - 6.4e-16 58.5 0.1 1.5e-15 57.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95238.1 - 1.9e-15 57.4 0.0 9.8e-15 55.1 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 ORX95238.1 - 3.8e-07 29.9 0.0 5.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 ORX95238.1 - 4.5e-07 29.4 0.0 6.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORX95238.1 - 5.8e-06 25.4 0.0 9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 ORX95238.1 - 0.00075 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORX95238.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX95238.1 - 0.0035 16.8 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 ORX95238.1 - 0.0049 16.4 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 ORX95238.1 - 0.0071 15.5 0.0 0.018 14.2 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase TehB PF03848.14 ORX95238.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 ORX95238.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 ORX95238.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RNA_pol_Rpb4 PF03874.16 ORX95239.1 - 6.5e-22 78.2 3.4 8.3e-22 77.8 3.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 SUa-2TM PF18179.1 ORX95239.1 - 0.086 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Gpi16 PF04113.14 ORX95241.1 - 3.6e-175 583.6 0.1 7e-174 579.4 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Homeodomain PF00046.29 ORX95241.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain Prothymosin PF03247.14 ORX95242.1 - 0.051 14.0 17.9 0.067 13.7 17.9 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.12 ORX95242.1 - 1.4 8.2 12.2 1.5 8.0 12.2 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 ORX95242.1 - 1.8 8.6 6.7 2.2 8.3 6.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal 4F5 PF04419.14 ORX95247.1 - 2e-06 28.5 8.7 3.2e-06 27.9 8.7 1.4 1 0 0 1 1 1 1 4F5 protein family Sel_put PF04328.13 ORX95247.1 - 0.0032 17.5 0.1 0.0067 16.4 0.1 1.4 1 0 0 1 1 1 1 Selenoprotein, putative zf-C2H2_4 PF13894.6 ORX95247.1 - 0.029 15.2 0.5 0.046 14.6 0.5 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met2 PF12907.7 ORX95247.1 - 0.033 14.3 4.7 0.11 12.6 4.7 1.8 1 1 0 1 1 1 0 Zinc-binding zf-C2H2_2 PF12756.7 ORX95247.1 - 0.072 13.4 0.1 0.072 13.4 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FixO PF02433.15 ORX95249.1 - 0.031 13.7 1.4 0.04 13.4 1.4 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO BatD PF13584.6 ORX95249.1 - 0.032 13.1 0.2 0.045 12.6 0.2 1.1 1 0 0 1 1 1 0 Oxygen tolerance Kelch_5 PF13854.6 ORX95251.1 - 0.0035 17.3 1.4 2.4 8.3 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 ORX95251.1 - 0.0085 16.4 0.7 28 5.2 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX95251.1 - 0.015 15.6 0.1 8.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 ORX95251.1 - 0.028 14.4 0.0 9.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 ORX95251.1 - 0.039 14.0 0.0 5.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF872 PF05915.12 ORX95261.1 - 7.7e-06 26.1 2.6 1.1e-05 25.6 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Phage_holin_3_6 PF07332.11 ORX95261.1 - 0.0017 18.4 1.8 0.0021 18.1 1.8 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF308 PF03729.13 ORX95261.1 - 0.075 13.4 9.8 0.11 12.8 9.6 1.4 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF2207 PF09972.9 ORX95261.1 - 0.92 8.2 3.3 1.1 7.9 3.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YtpI PF14007.6 ORX95261.1 - 2.1 8.5 7.1 0.68 10.1 0.5 2.4 2 1 0 2 2 2 0 YtpI-like protein ATP1G1_PLM_MAT8 PF02038.16 ORX95261.1 - 2.5 7.6 4.5 6.1 6.4 0.1 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF3149 PF11346.8 ORX95261.1 - 4.9 6.8 12.1 0.1 12.3 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) bZIP_1 PF00170.21 ORX95262.1 - 2.2e-13 50.1 9.9 2.2e-13 50.1 9.9 2.0 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORX95262.1 - 6.2e-07 29.4 13.2 7e-07 29.2 11.1 2.1 1 1 1 2 2 2 2 Basic region leucine zipper CDC45 PF02724.14 ORX95262.1 - 0.16 10.3 7.0 0.17 10.1 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 ORX95262.1 - 0.18 10.3 9.2 0.23 10.0 9.2 1.0 1 0 0 1 1 1 0 Macoilin family SprA-related PF12118.8 ORX95262.1 - 0.36 9.9 6.4 0.46 9.6 6.4 1.1 1 0 0 1 1 1 0 SprA-related family FAM76 PF16046.5 ORX95262.1 - 0.36 10.1 11.9 0.45 9.8 11.9 1.1 1 0 0 1 1 1 0 FAM76 protein ACR_tran PF00873.19 ORX95262.1 - 0.54 7.8 1.3 0.58 7.7 1.3 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Mem_trans PF03547.18 ORX95262.1 - 8.1 4.7 5.8 10 4.4 5.8 1.1 1 0 0 1 1 1 0 Membrane transport protein SH3_9 PF14604.6 ORX95263.1 - 3.7e-09 36.3 0.1 8.1e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX95263.1 - 7.3e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX95263.1 - 0.00049 19.7 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ANAPC4_WD40 PF12894.7 ORX95264.1 - 2.4e-12 47.0 0.1 0.034 14.5 0.0 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORX95264.1 - 1.8e-11 44.3 5.7 0.012 16.5 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 ORX95264.1 - 7.9e-05 22.6 0.1 0.034 14.0 0.1 3.5 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 ORX95264.1 - 0.00014 22.2 0.0 5.5 7.6 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain Mcl1_mid PF12341.8 ORX95264.1 - 0.00015 21.2 0.3 0.65 9.3 0.0 2.7 1 1 1 3 3 3 2 Minichromosome loss protein, Mcl1, middle region Helo_like_N PF17111.5 ORX95264.1 - 0.023 14.1 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins OSCP PF00213.18 ORX95264.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF641 PF04859.12 ORX95264.1 - 0.16 12.3 0.1 0.41 11.0 0.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HAUS5 PF14817.6 ORX95264.1 - 0.23 10.2 1.0 0.33 9.7 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 WW PF00397.26 ORX95265.1 - 4.1e-09 36.4 6.5 1.2e-08 34.9 5.5 2.4 2 0 0 2 2 2 1 WW domain Cyclin PF08613.11 ORX95266.1 - 5e-12 46.5 0.0 7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX95266.1 - 0.0034 17.1 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain 4HBT PF03061.22 ORX95267.1 - 1.5e-11 44.4 0.0 2.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Atg14 PF10186.9 ORX95268.1 - 2.1e-14 53.3 5.1 2.9e-14 52.9 5.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 PAS PF00989.25 ORX95269.1 - 4.7e-09 36.3 0.0 6.1e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX95269.1 - 5.7e-08 32.9 0.0 0.004 17.4 0.0 2.6 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 ORX95269.1 - 1.7e-05 25.0 0.0 0.00026 21.2 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX95269.1 - 0.0067 16.7 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ORX95269.1 - 0.094 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain CorA PF01544.18 ORX95270.1 - 4.2e-48 164.2 0.7 5.1e-48 163.9 0.7 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FA_desaturase PF00487.24 ORX95271.1 - 2.6e-21 76.6 15.4 4.1e-21 76.0 15.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 ORX95271.1 - 2e-10 39.9 0.6 2e-10 39.9 0.6 2.3 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Arf PF00025.21 ORX95273.1 - 4.7e-76 254.1 0.0 5.1e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX95273.1 - 1.6e-14 54.1 0.0 2.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORX95273.1 - 4.3e-12 45.9 0.0 5.5e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORX95273.1 - 1.2e-10 41.1 0.1 4.3e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORX95273.1 - 2.2e-10 40.2 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX95273.1 - 4.5e-09 36.0 0.0 5.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX95273.1 - 3.4e-05 23.9 0.0 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORX95273.1 - 0.0014 18.2 0.0 0.013 15.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 ORX95273.1 - 0.026 15.1 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORX95273.1 - 0.074 12.6 0.0 9 5.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORX95273.1 - 0.11 13.0 0.1 0.14 12.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Hydrolase PF00702.26 ORX95274.1 - 1.1e-16 61.8 1.3 1.1e-15 58.5 1.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX95274.1 - 1.4e-16 61.5 0.0 3e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX95274.1 - 7.9e-10 38.9 1.2 7.3e-09 35.7 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SPX PF03105.19 ORX95274.1 - 3.9e-09 36.9 3.7 3.2e-06 27.3 0.2 3.1 2 1 1 3 3 3 2 SPX domain ACT_6 PF13740.6 ORX95274.1 - 2.8e-06 27.2 0.0 6.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 ACT domain Put_Phosphatase PF06888.12 ORX95274.1 - 9.5e-05 21.9 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.6 ORX95274.1 - 0.0072 16.4 0.5 0.49 10.5 0.5 3.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase IES5 PF17335.2 ORX95274.1 - 0.047 13.9 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ino80 complex subunit 5 DUF705 PF05152.12 ORX95274.1 - 0.048 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Peptidase_M28 PF04389.17 ORX95275.1 - 8.6e-22 77.8 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORX95275.1 - 5.7e-10 39.2 0.1 2.7e-09 37.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 ORX95275.1 - 4.6e-06 26.6 0.1 9.9e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 PA domain Anoctamin PF04547.12 ORX95276.1 - 1.1e-103 347.5 16.1 1.3e-103 347.2 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pkinase PF00069.25 ORX95277.1 - 2e-43 148.6 0.2 2.1e-21 76.5 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95277.1 - 6e-15 55.2 0.1 1.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PBP1_TM PF14812.6 ORX95277.1 - 0.11 12.9 6.8 0.26 11.7 6.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RIO1 PF01163.22 ORX95277.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Cwf_Cwc_15 PF04889.12 ORX95277.1 - 0.75 9.5 6.1 1.2 8.8 6.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 ORX95277.1 - 0.85 10.0 14.7 2.1 8.8 14.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 ORX95277.1 - 2.8 5.9 5.3 4.2 5.4 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 ORX95277.1 - 5.5 6.2 6.3 8.5 5.6 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_4 PF13637.6 ORX95278.1 - 6.5e-09 36.2 0.1 2e-06 28.2 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORX95278.1 - 2.9e-07 30.3 0.3 2e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 ORX95278.1 - 4.4e-06 27.2 0.0 5.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORX95278.1 - 8.4e-05 22.8 0.7 0.00026 21.3 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 ORX95278.1 - 0.0046 17.2 0.2 0.074 13.4 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Arrestin_N PF00339.29 ORX95279.1 - 1.1e-11 44.9 0.9 5.8e-10 39.4 0.2 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX95279.1 - 1.2e-09 38.7 0.1 0.00044 20.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX95279.1 - 0.029 14.1 0.0 0.29 10.8 0.0 2.1 1 1 1 2 2 2 0 Arrestin_N terminal like DEAD PF00270.29 ORX95280.1 - 3.7e-21 75.7 0.0 9.7e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX95280.1 - 9.2e-13 48.5 0.2 7.3e-12 45.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX95280.1 - 2.5e-06 27.6 0.8 5.2e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 ORX95280.1 - 0.00037 20.9 0.2 0.0025 18.1 0.2 2.3 2 0 0 2 2 2 1 DNA replication factor CDT1 like GST_N_3 PF13417.6 ORX95286.1 - 2.4e-05 24.6 0.0 5.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX95286.1 - 4.5e-05 23.7 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX95286.1 - 0.00013 21.9 0.2 0.00027 20.9 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX95286.1 - 0.0012 19.0 0.1 0.0038 17.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX95286.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lipase_3 PF01764.25 ORX95287.1 - 1.1e-28 99.9 0.0 1.7e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX95287.1 - 0.0011 19.6 0.2 0.018 15.7 0.0 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORX95287.1 - 0.036 13.6 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Cutinase PF01083.22 ORX95287.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Cutinase 4HBT PF03061.22 ORX95288.1 - 1.5e-08 34.9 0.0 2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 ORX95288.1 - 0.0065 16.6 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) GPCR_chapero_1 PF11904.8 ORX95291.1 - 8.9e-13 48.3 0.0 2.8e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 ORX95291.1 - 0.0014 19.1 0.1 0.0055 17.3 0.1 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX95291.1 - 0.0064 16.9 0.1 0.041 14.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 ORX95291.1 - 0.011 16.1 0.4 0.027 14.9 0.4 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 ORX95291.1 - 0.077 13.6 0.1 0.65 10.7 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ArfGap PF01412.18 ORX95294.1 - 5.5e-39 132.9 0.1 9e-39 132.2 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Cytochrome_CBB3 PF13442.6 ORX95294.1 - 0.17 12.3 0.2 0.4 11.0 0.2 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Syntaxin-18_N PF10496.9 ORX95295.1 - 0.016 15.5 0.8 0.046 14.0 0.8 1.8 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Myb_CC_LHEQLE PF14379.6 ORX95295.1 - 0.099 12.4 2.3 0.29 10.9 0.1 2.4 1 1 1 2 2 2 0 MYB-CC type transfactor, LHEQLE motif DIM1 PF02966.16 ORX95298.1 - 5.3e-68 226.9 0.1 5.9e-68 226.7 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORX95298.1 - 3.3e-05 23.8 0.0 4.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORX95298.1 - 0.072 13.4 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Lactamase_B PF00753.27 ORX95299.1 - 1.6e-21 77.3 0.5 4.9e-21 75.6 0.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX95299.1 - 1.8e-06 27.6 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 ORX95299.1 - 2.7e-05 24.1 0.0 5.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 ORX95299.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Band_7 PF01145.25 ORX95300.1 - 4.8e-27 95.1 0.9 6.8e-27 94.6 0.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX95300.1 - 0.0086 15.8 0.1 0.017 14.9 0.1 1.5 1 1 0 1 1 1 1 SPFH domain-Band 7 family eRF1_3 PF03465.15 ORX95300.1 - 0.049 14.1 0.1 0.22 12.0 0.1 2.2 1 1 0 1 1 1 0 eRF1 domain 3 LRS4 PF10422.9 ORX95300.1 - 0.05 13.2 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Peripla_BP_2 PF01497.18 ORX95301.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein MIP PF00230.20 ORX95302.1 - 5.8e-17 62.2 11.7 7.3e-17 61.8 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein YjbH PF06082.11 ORX95322.1 - 4.7 5.9 13.3 6.4 5.5 12.5 1.4 1 1 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH HIG_1_N PF04588.13 ORX95323.1 - 4.3e-16 58.9 3.0 6.9e-16 58.2 3.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Chor_lyase PF04345.13 ORX95323.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Chorismate lyase ETRAMP PF09716.10 ORX95323.1 - 0.082 13.0 0.2 1.5 9.0 0.0 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Aminotran_5 PF00266.19 ORX95324.1 - 1e-63 215.6 0.0 6.8e-62 209.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORX95324.1 - 5e-08 31.9 0.2 1.1e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORX95324.1 - 5.9e-06 25.8 0.1 9.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ORX95324.1 - 8.2e-06 25.2 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II UNC-50 PF05216.13 ORX95326.1 - 1.2e-82 276.7 20.1 1.4e-82 276.6 20.1 1.0 1 0 0 1 1 1 1 UNC-50 family Mntp PF02659.15 ORX95326.1 - 0.006 16.3 0.1 0.085 12.6 0.0 2.2 2 0 0 2 2 2 1 Putative manganese efflux pump Myb_DNA-binding PF00249.31 ORX95327.1 - 2e-46 155.9 11.9 6e-16 58.4 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX95327.1 - 2.2e-39 133.5 8.2 1.3e-18 66.9 0.2 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain zf-C2H2 PF00096.26 ORX95327.1 - 6.7e-06 26.3 26.7 0.006 17.0 2.1 5.2 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORX95327.1 - 0.00029 21.1 13.3 0.12 12.5 1.1 3.5 2 2 2 4 4 4 2 Aberrant zinc-finger Rap1_C PF11626.8 ORX95327.1 - 0.0005 20.1 3.9 0.16 12.1 0.4 3.2 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 ORX95327.1 - 0.0012 18.8 0.0 4 7.5 0.0 3.5 1 1 2 3 3 3 1 SLIDE zf-C2H2_8 PF15909.5 ORX95327.1 - 0.0013 19.0 1.5 0.076 13.3 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc ribbon MADF_DNA_bdg PF10545.9 ORX95327.1 - 0.01 16.1 7.2 6.4 7.2 0.4 3.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 ORX95327.1 - 0.024 15.0 6.3 0.37 11.2 0.4 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain UBM PF14377.6 ORX95327.1 - 0.029 13.8 0.8 0.13 11.8 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin binding region Myb_DNA-bind_7 PF15963.5 ORX95327.1 - 0.029 14.2 1.9 2.9 7.9 0.1 3.8 3 1 1 4 4 4 0 Myb DNA-binding like zf_Hakai PF18408.1 ORX95327.1 - 0.031 14.0 0.0 0.031 14.0 0.0 3.6 4 0 0 4 4 3 0 C2H2 Hakai zinc finger domain zf-H2C2_2 PF13465.6 ORX95327.1 - 0.66 10.5 22.5 0.47 11.0 0.5 5.8 6 0 0 6 6 6 0 Zinc-finger double domain zf-RRN7 PF11781.8 ORX95327.1 - 0.67 9.7 8.4 13 5.6 0.6 4.2 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_jaz PF12171.8 ORX95327.1 - 1.1 9.6 6.8 21 5.5 0.0 3.8 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORX95327.1 - 1.7 9.7 35.1 0.23 12.4 1.3 6.0 7 0 0 7 7 5 0 C2H2-type zinc finger Yae1_N PF09811.9 ORX95328.1 - 9.3e-11 41.3 29.2 3.1e-05 23.6 6.4 4.4 1 1 3 4 4 4 4 Essential protein Yae1, N terminal F5_F8_type_C PF00754.25 ORX95329.1 - 6.6e-08 32.7 0.0 9.9e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 ORX95329.1 - 2.4e-06 27.6 0.0 1.1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal ANAPC10 PF03256.16 ORX95329.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Asp PF00026.23 ORX95330.1 - 1.6e-102 343.2 1.0 1.9e-102 342.9 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX95330.1 - 1.2e-15 58.2 3.0 3e-10 40.6 0.2 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX95330.1 - 1.5e-06 28.1 0.0 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ORX95330.1 - 0.0028 18.2 0.3 0.99 10.0 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORX95330.1 - 0.0081 16.8 1.8 0.18 12.4 0.3 2.9 2 1 0 2 2 2 1 Aspartyl protease ABC_tran PF00005.27 ORX95331.1 - 4.4e-27 95.3 0.0 7.6e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORX95331.1 - 2.8e-17 62.8 11.8 2.8e-17 62.8 11.8 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ORX95331.1 - 0.00011 21.4 12.7 0.00011 21.4 12.7 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX95331.1 - 0.0004 20.3 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORX95331.1 - 0.0012 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX95331.1 - 0.008 16.5 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORX95331.1 - 0.011 15.4 0.7 0.026 14.2 0.7 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 ORX95331.1 - 0.014 15.5 0.0 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 ORX95331.1 - 0.015 15.4 0.4 0.029 14.5 0.4 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase JAMP PF05571.12 ORX95331.1 - 0.024 14.3 1.8 0.044 13.4 1.8 1.4 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein AAA_21 PF13304.6 ORX95331.1 - 0.032 14.1 1.1 5 6.8 0.0 2.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dicer_N PF17895.1 ORX95331.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain AAA_24 PF13479.6 ORX95331.1 - 0.081 12.6 0.7 0.15 11.7 0.4 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORX95331.1 - 0.1 12.2 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain Adeno_E3_CR2 PF02439.15 ORX95331.1 - 0.18 11.6 3.2 0.42 10.4 3.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA_30 PF13604.6 ORX95331.1 - 0.27 10.9 0.0 0.44 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain CorA PF01544.18 ORX95331.1 - 0.36 10.1 0.0 0.36 10.1 0.0 2.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Toxin_12 PF07740.12 ORX95331.1 - 2 9.2 4.5 0.8 10.4 1.3 2.0 2 0 0 2 2 1 0 Ion channel inhibitory toxin FixQ PF05545.11 ORX95331.1 - 2.8 8.0 8.0 1.9 8.5 1.1 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Lustrin_cystein PF14625.6 ORX95331.1 - 7.8 7.0 25.7 6.7 7.2 10.6 3.1 2 1 1 3 3 3 0 Lustrin, cysteine-rich repeated domain Med20 PF08612.11 ORX95332.1 - 3.9e-31 108.2 0.0 4.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Cyto_heme_lyase PF01265.17 ORX95333.1 - 5.4e-73 246.1 7.8 4.8e-72 243.0 7.8 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase ATG101 PF07855.12 ORX95334.1 - 5e-53 179.2 0.9 6.3e-53 178.9 0.9 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 CENP-T_C PF15511.6 ORX95335.1 - 1.9e-08 34.4 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORX95335.1 - 2.8e-05 24.2 0.1 4e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORX95335.1 - 6.3e-05 23.4 0.2 7.2e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX95335.1 - 9.2e-05 22.8 0.1 0.00012 22.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX95335.1 - 0.00013 22.1 0.1 0.00024 21.3 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX95335.1 - 0.022 14.8 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX95335.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORX95335.1 - 0.18 12.3 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Peptidase_M24 PF00557.24 ORX95336.1 - 3.4e-61 206.6 0.1 4.4e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORX95336.1 - 8.7e-20 70.7 0.0 1.7e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DPPIV_N PF00930.21 ORX95337.1 - 1.9e-105 352.5 3.8 2.5e-105 352.1 3.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORX95337.1 - 2.4e-41 141.5 0.4 5.1e-41 140.5 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORX95337.1 - 0.0033 17.1 1.1 0.032 13.8 0.4 2.5 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ORX95337.1 - 0.039 13.6 0.2 0.095 12.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX95337.1 - 0.054 14.1 0.0 1.8 9.1 0.0 2.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family DPPIV_N PF00930.21 ORX95338.1 - 3.2e-106 355.1 4.3 4.2e-106 354.7 4.3 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORX95338.1 - 4.2e-47 160.4 0.2 8e-47 159.4 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORX95338.1 - 0.0074 15.9 6.3 0.034 13.7 0.3 2.9 2 2 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ORX95338.1 - 0.054 13.1 0.2 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 ORX95339.1 - 1.6e-08 34.3 0.0 5.6e-07 29.3 0.0 2.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ORX95339.1 - 1e-05 25.5 0.5 0.038 13.8 0.0 3.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ORX95339.1 - 0.00011 21.9 0.3 0.0018 18.0 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX95339.1 - 0.03 13.6 0.1 0.16 11.2 0.1 2.0 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 ORX95339.1 - 0.081 12.6 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 ORX95339.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 ORX95339.1 - 0.088 12.5 0.0 0.23 11.1 0.0 1.6 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Methyltransf_23 PF13489.6 ORX95340.1 - 1.8e-17 63.7 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX95340.1 - 2.3e-17 63.5 0.0 3.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX95340.1 - 1.5e-16 60.8 0.0 2.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95340.1 - 1e-13 51.9 0.0 1.6e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95340.1 - 1.5e-09 37.8 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX95340.1 - 6.4e-08 32.2 0.0 8.6e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ORX95340.1 - 2.7e-05 23.6 0.0 3.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 ORX95340.1 - 9.7e-05 22.1 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 ORX95340.1 - 0.00023 20.7 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 ORX95340.1 - 0.00038 20.6 0.0 0.0011 19.1 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 ORX95340.1 - 0.00054 19.4 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 ORX95340.1 - 0.0051 16.5 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) N2227 PF07942.12 ORX95340.1 - 0.026 13.7 0.2 0.16 11.2 0.2 1.9 1 1 1 2 2 2 0 N2227-like protein MTS PF05175.14 ORX95340.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 ORX95340.1 - 0.046 13.2 0.0 9.1 5.7 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.18 ORX95340.1 - 0.068 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Tyrosinase PF00264.20 ORX95341.1 - 3.4e-34 119.1 15.6 4.5e-34 118.7 11.5 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase DSPc PF00782.20 ORX95342.1 - 1e-32 112.7 0.1 2.1e-32 111.7 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX95342.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 ORX95343.1 - 1.2e-153 511.2 3.1 1.5e-153 510.9 3.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 ORX95343.1 - 0.0006 19.6 0.2 0.0015 18.4 0.2 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX95343.1 - 0.013 15.0 0.2 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORX95343.1 - 0.015 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family HTH_29 PF13551.6 ORX95343.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix FAD_binding_4 PF01565.23 ORX95345.1 - 2e-30 105.4 1.5 3.2e-30 104.7 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX95345.1 - 6.4e-05 23.0 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Hva1_TUDOR PF11160.8 ORX95346.1 - 7.3e-12 45.3 0.1 9.3e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Hva1_TUDOR PF11160.8 ORX95347.1 - 1.2e-14 54.2 0.4 1.4e-14 54.0 0.4 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Polysacc_deac_1 PF01522.21 ORX95348.1 - 1.8e-33 115.1 0.0 2.9e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3783 PF12646.7 ORX95349.1 - 0.14 12.1 0.2 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) SH3_1 PF00018.28 ORX95362.1 - 9.1e-19 66.8 4.5 2.5e-13 49.4 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORX95362.1 - 1e-15 57.3 6.0 2.9e-07 30.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORX95362.1 - 1.5e-10 40.6 0.2 2.5e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 ORX95362.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HisKA PF00512.25 ORX95362.1 - 2.7 8.1 11.0 0.25 11.4 0.2 3.5 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain Chitin_synth_2 PF03142.15 ORX95363.1 - 2e-253 841.8 0.2 2.8e-253 841.3 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX95363.1 - 1.2e-13 51.6 0.0 7.3e-13 48.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX95363.1 - 2.8e-10 40.4 8.0 2.8e-10 40.4 8.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX95363.1 - 0.00054 19.5 0.0 0.46 9.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX95363.1 - 0.048 13.5 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 ORX95363.1 - 0.085 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain PAS_3 PF08447.12 ORX95364.1 - 2.5e-05 24.5 0.0 4.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORX95364.1 - 0.00039 20.4 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 PAS fold Fungal_trans PF04082.18 ORX95365.1 - 4.4e-38 130.8 0.4 4.4e-38 130.8 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX95365.1 - 8.6e-10 38.6 9.2 1.5e-09 37.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPMO_10 PF03067.15 ORX95368.1 - 1.1e-06 29.4 0.0 4.6e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading NIF PF03031.18 ORX95369.1 - 5.6e-53 178.9 0.1 8.7e-53 178.3 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PurK_C PF17769.1 ORX95369.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain SPRY PF00622.28 ORX95370.1 - 1.9e-15 57.0 0.1 2.1e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 SPRY domain DUF1883 PF08980.10 ORX95370.1 - 0.098 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) Sel1 PF08238.12 ORX95382.1 - 4.7e-28 97.0 3.3 4.1e-05 24.1 0.3 5.4 5 0 0 5 5 5 5 Sel1 repeat CS PF04969.16 ORX95382.1 - 1.8e-08 35.3 0.0 4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 CS domain MIT PF04212.18 ORX95382.1 - 8.1e-05 22.6 2.0 0.04 14.0 0.0 3.7 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 ORX95382.1 - 0.011 16.3 0.6 4.4 8.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95382.1 - 0.023 14.5 2.6 6.5 6.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX95382.1 - 0.073 13.2 1.6 28 5.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 ORX95382.1 - 0.078 12.8 1.6 0.11 12.4 1.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.12 ORX95382.1 - 0.35 9.8 8.6 0.56 9.1 8.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TPR_8 PF13181.6 ORX95382.1 - 0.45 10.9 7.7 1.1 9.6 0.2 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat PBP1_TM PF14812.6 ORX95382.1 - 0.7 10.3 7.7 1.4 9.4 7.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CCDC106 PF15794.5 ORX95382.1 - 2.6 7.7 10.6 4.3 7.0 10.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF5427 PF10310.9 ORX95382.1 - 3.8 6.4 6.9 5.2 5.9 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF3381 PF11861.8 ORX95382.1 - 4 7.2 8.9 6.3 6.6 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 ORX95382.1 - 8.1 4.6 7.5 12 4.0 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 ORX95383.1 - 2.4e-56 191.1 0.1 1.3e-40 139.5 0.1 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95383.1 - 4.7e-32 111.3 0.0 5.2e-25 88.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORX95383.1 - 2.3e-05 23.9 0.0 0.17 11.1 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 ORX95383.1 - 0.0064 15.3 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX95383.1 - 0.077 12.9 0.0 0.42 10.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.22 ORX95384.1 - 4.2e-08 33.7 1.6 8.3e-08 32.8 1.6 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX95384.1 - 2.2e-05 24.6 0.2 7.6e-05 22.8 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX95384.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like Arrestin_C PF02752.22 ORX95385.1 - 1.7e-09 38.3 0.3 6.8e-09 36.3 0.1 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX95385.1 - 0.00011 22.3 0.0 0.0013 18.8 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PLAC PF08686.11 ORX95385.1 - 0.13 13.1 0.7 1.1 10.1 0.2 2.4 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain Tetraspanin PF00335.20 ORX95386.1 - 7.4e-12 45.5 3.7 1.1e-11 44.9 3.7 1.3 1 0 0 1 1 1 1 Tetraspanin family COX2_TM PF02790.15 ORX95386.1 - 0.22 11.7 3.3 8.9 6.5 0.4 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Arteri_Gl PF00951.18 ORX95386.1 - 0.93 9.3 5.5 4 7.2 0.8 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Glyco_hydro_9 PF00759.19 ORX95387.1 - 3e-98 330.0 18.1 3.6e-98 329.7 18.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Prenyltrans PF00432.21 ORX95387.1 - 0.13 12.0 0.6 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Chitin_bind_1 PF00187.19 ORX95388.1 - 6.1e-15 55.4 46.4 3.5e-07 30.6 18.4 2.8 2 2 0 2 2 2 2 Chitin recognition protein Polysacc_deac_1 PF01522.21 ORX95389.1 - 3.2e-28 98.1 0.0 4.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX95389.1 - 1.6e-07 31.6 20.9 3.1e-07 30.8 20.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 ORX95389.1 - 0.039 13.6 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) RAP PF08373.10 ORX95389.1 - 0.15 12.2 1.2 0.89 9.7 0.2 2.6 3 0 0 3 3 3 0 RAP domain GPI-anchored PF10342.9 ORX95390.1 - 2e-16 60.5 5.2 1.3e-09 38.6 0.7 2.1 2 0 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_4 PF13754.6 ORX95390.1 - 0.15 11.8 0.3 16 5.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function Peptidase_M49 PF03571.15 ORX95391.1 - 2.5e-249 828.3 0.1 4.1e-249 827.6 0.1 1.3 2 0 0 2 2 2 1 Peptidase family M49 ADH_zinc_N_2 PF13602.6 ORX95392.1 - 2.3e-15 57.8 0.0 3.9e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORX95392.1 - 2.6e-13 50.1 0.0 4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX95392.1 - 5.4e-09 35.9 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORX95392.1 - 0.16 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ubiquitin_4 PF18036.1 ORX95393.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain CDC37_C PF08564.10 ORX95393.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain DUF1854 PF08909.11 ORX95394.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) Kelch_6 PF13964.6 ORX95396.1 - 0.00089 19.5 0.2 7.4 7.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 ORX95396.1 - 0.0014 18.6 0.9 1.2 9.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 ORX95396.1 - 0.0017 18.4 0.3 3.3 7.8 0.0 3.2 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 ORX95396.1 - 0.002 18.3 0.6 8.2 6.9 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 ORX95396.1 - 0.0047 16.8 0.0 4.5 7.4 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Helicase_C PF00271.31 ORX95397.1 - 5.2e-07 30.0 0.1 6.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cytochrom_B562 PF07361.11 ORX95413.1 - 0.044 14.4 1.2 0.081 13.6 1.2 1.4 1 0 0 1 1 1 0 Cytochrome b562 dNK PF01712.19 ORX95413.1 - 0.1 12.4 1.8 0.14 12.0 1.5 1.4 1 1 0 1 1 1 0 Deoxynucleoside kinase AMP-binding PF00501.28 ORX95414.1 - 4.5e-08 32.1 0.7 0.00034 19.3 0.1 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding PF00501.28 ORX95415.1 - 2.7e-06 26.2 0.1 2.8e-06 26.2 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORX95416.1 - 2.4e-14 53.4 0.0 3.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 ORX95416.1 - 1.3e-06 27.4 0.0 1.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 ORX95417.1 - 1.5e-16 60.0 0.0 1.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 ORX95418.1 - 1.1e-26 94.0 0.0 1.7e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORX95418.1 - 9.4e-15 54.6 9.0 9.4e-15 54.6 9.0 2.3 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORX95418.1 - 0.00053 19.9 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 ORX95418.1 - 0.00069 18.8 8.7 0.00069 18.8 8.7 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX95418.1 - 0.0043 16.9 3.4 1.2 8.9 0.0 2.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 ORX95418.1 - 0.0047 16.3 4.3 0.0047 16.3 4.3 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 ORX95418.1 - 0.036 14.1 0.2 0.085 12.9 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORX95418.1 - 0.051 13.3 0.4 0.1 12.3 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORX95418.1 - 0.056 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX95418.1 - 0.058 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX95418.1 - 0.085 13.1 0.1 0.97 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF3792 PF12670.7 ORX95418.1 - 0.18 12.0 11.6 0.082 13.1 5.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) AAA_25 PF13481.6 ORX95418.1 - 0.21 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tetraspanin PF00335.20 ORX95418.1 - 0.32 10.7 3.6 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Tetraspanin family DUF4131 PF13567.6 ORX95418.1 - 1.1 8.9 5.2 1.6 8.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Toxin_7 PF05980.12 ORX95418.1 - 5.4 7.3 9.1 13 6.1 0.8 2.8 1 1 1 2 2 2 0 Toxin 7 COX6A PF02046.15 ORX95419.1 - 1.6e-30 105.8 0.1 1.8e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa SRF-TF PF00319.18 ORX95420.1 - 1.2e-20 72.7 0.1 1.9e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Rad52_Rad22 PF04098.15 ORX95421.1 - 4.7e-52 176.0 0.1 7e-52 175.4 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PQ-loop PF04193.14 ORX95422.1 - 8.2e-20 70.3 2.3 1.5e-14 53.5 0.4 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 ORX95422.1 - 0.00011 23.0 4.5 0.00017 22.4 4.2 1.5 1 1 0 1 1 1 1 ER lumen protein retaining receptor RRM_1 PF00076.22 ORX95423.1 - 7.2e-34 115.4 2.0 1.1e-14 54.0 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX95423.1 - 1.9e-07 30.8 0.0 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORX95423.1 - 9.7e-07 28.8 0.0 0.0029 17.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif Spo7_2_N PF15407.6 ORX95423.1 - 0.0078 15.8 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 2 Sporulation protein family 7 Nup35_RRM_2 PF14605.6 ORX95423.1 - 0.021 14.8 0.1 0.66 10.0 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_9 PF18444.1 ORX95423.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif SH3_6 PF12913.7 ORX95423.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) DUF1866 PF08952.11 ORX95423.1 - 0.14 12.0 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Methyltransf_23 PF13489.6 ORX95424.1 - 5.8e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX95424.1 - 0.00063 20.4 0.1 0.0066 17.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 ORX95424.1 - 0.0022 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_11 PF08241.12 ORX95424.1 - 0.003 18.1 0.1 0.012 16.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95424.1 - 0.0035 17.1 0.0 0.012 15.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95424.1 - 0.017 15.9 0.0 0.058 14.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF4379 PF14311.6 ORX95424.1 - 0.043 14.2 1.2 0.1 13.0 1.2 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain DASH_Dad4 PF08650.10 ORX95425.1 - 2.2e-23 82.0 5.6 2.4e-23 81.9 5.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 ORX95425.1 - 8.1e-05 22.7 5.4 0.00011 22.3 5.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 Mce4_CUP1 PF11887.8 ORX95425.1 - 0.0071 15.8 0.1 0.0082 15.6 0.1 1.0 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Matrilin_ccoil PF10393.9 ORX95425.1 - 0.033 14.0 0.4 0.059 13.2 0.4 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DASH_Duo1 PF08651.10 ORX95425.1 - 0.037 13.8 1.8 0.048 13.4 1.8 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF948 PF06103.11 ORX95425.1 - 0.042 14.1 0.2 0.047 14.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0193 PF05250.11 ORX95425.1 - 0.11 12.3 1.4 0.12 12.1 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Myb_DNA-bind_7 PF15963.5 ORX95426.1 - 5.7e-23 80.6 0.1 5.7e-23 80.6 0.1 1.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORX95426.1 - 1e-10 41.6 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX95426.1 - 9.6e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lipoprotein_15 PF03640.15 ORX95426.1 - 0.05 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Secreted repeat of unknown function PAN_1 PF00024.26 ORX95427.1 - 0.00061 19.7 2.0 0.13 12.2 0.3 2.2 2 0 0 2 2 2 2 PAN domain Pyrid_oxidase_2 PF13883.6 ORX95428.1 - 4.2e-33 114.7 0.0 4.7e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ORX95428.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase eIF-1a PF01176.19 ORX95429.1 - 3e-17 62.2 0.2 4.3e-17 61.7 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RNB PF00773.19 ORX95430.1 - 4.4e-27 95.3 0.0 7.6e-27 94.5 0.0 1.4 1 1 0 1 1 1 1 RNB domain RNase_II_C_S1 PF18614.1 ORX95430.1 - 0.038 13.9 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain FAD_binding_1 PF00667.20 ORX95431.1 - 8.6e-64 215.1 0.0 1.5e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 ORX95431.1 - 2.4e-34 119.1 0.6 4.2e-34 118.3 0.6 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_7 PF13241.6 ORX95431.1 - 1.8e-15 57.2 0.1 8.4e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_1 PF00175.21 ORX95431.1 - 5.8e-11 43.0 0.0 2.1e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 ORX95431.1 - 3.2e-09 37.1 0.0 7.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 ORX95431.1 - 1.8e-08 34.6 0.0 5.2e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF4203 PF13886.6 ORX95432.1 - 2.5e-24 86.1 24.1 3.1e-24 85.8 24.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) zf-BED PF02892.15 ORX95433.1 - 3.2e-05 23.9 0.0 0.0001 22.3 0.0 1.8 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_4 PF13894.6 ORX95433.1 - 0.059 14.2 0.3 0.18 12.7 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORX95433.1 - 0.068 13.1 1.0 0.17 11.8 1.0 1.7 1 1 0 1 1 1 0 zinc-finger of a C2HC-type Sod_Fe_C PF02777.18 ORX95434.1 - 1.2e-28 99.3 0.8 4.1e-27 94.3 0.8 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORX95434.1 - 1.9e-08 34.6 0.1 3.3e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain LSM PF01423.22 ORX95435.1 - 5.2e-18 64.5 0.2 6.7e-18 64.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain Ras PF00071.22 ORX95436.1 - 2.3e-51 173.6 0.0 2.7e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95436.1 - 6.5e-21 74.8 0.0 9.6e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95436.1 - 1.5e-08 34.3 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX95436.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX95436.1 - 0.089 12.1 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_L5_C PF00673.21 ORX95437.1 - 1.2e-22 79.9 0.0 1.7e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORX95437.1 - 3e-22 78.7 0.0 1.9e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Zona_pellucida PF00100.23 ORX95437.1 - 0.013 15.4 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain HTH_ABP1_N PF18107.1 ORX95437.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Na_Ca_ex PF01699.24 ORX95438.1 - 2.5e-47 160.6 41.1 1.4e-25 90.1 17.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TFIIB PF00382.19 ORX95439.1 - 1.6e-39 133.8 2.1 2.1e-19 69.3 0.2 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 ORX95439.1 - 1.1e-28 99.6 9.6 1.1e-28 99.6 9.6 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 ORX95439.1 - 8.6e-11 41.2 3.0 2.6e-10 39.6 3.0 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ORX95439.1 - 3.2e-05 23.7 0.3 0.02 14.6 0.2 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 ORX95439.1 - 0.0084 16.1 0.2 0.0084 16.1 0.2 2.2 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DZR PF12773.7 ORX95439.1 - 0.068 13.2 0.6 0.16 12.0 0.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 ORX95439.1 - 0.11 11.9 1.9 0.64 9.5 1.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 ORX95439.1 - 0.15 11.8 2.0 0.29 10.9 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 YhfH PF14149.6 ORX95439.1 - 0.25 11.4 4.5 4.1 7.5 0.2 2.6 1 1 1 2 2 2 0 YhfH-like protein zinc_ribbon_2 PF13240.6 ORX95439.1 - 0.36 10.6 2.5 2.3 8.1 0.3 2.4 1 1 1 2 2 2 0 zinc-ribbon domain MMACHC PF16690.5 ORX95440.1 - 2.8e-10 40.2 0.6 9.1e-09 35.3 0.6 2.3 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Methyltransf_31 PF13847.6 ORX95441.1 - 1.8e-15 57.0 0.0 2.4e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX95441.1 - 1.1e-14 54.5 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX95441.1 - 2.1e-14 53.9 0.0 3.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX95441.1 - 3.9e-12 46.7 0.0 6.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95441.1 - 4.5e-12 46.6 0.0 6.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX95441.1 - 4.4e-06 26.2 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORX95441.1 - 1e-05 25.0 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ORX95441.1 - 0.00012 21.1 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ORX95441.1 - 0.0033 17.0 0.0 0.0065 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORX95441.1 - 0.0048 16.3 0.0 0.0066 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 ORX95441.1 - 0.0084 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 ORX95441.1 - 0.048 13.1 0.3 0.14 11.6 0.1 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain RrnaAD PF00398.20 ORX95441.1 - 0.054 12.6 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 ORX95441.1 - 0.069 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 ORX95441.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 ORX95441.1 - 0.094 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) BBL5 PF07289.11 ORX95441.1 - 0.095 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein MethyltransfD12 PF02086.15 ORX95441.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase HEAT_2 PF13646.6 ORX95442.1 - 1.3e-33 115.2 0.0 3.5e-13 49.8 0.0 3.8 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 ORX95442.1 - 1.8e-27 93.2 0.0 0.00017 21.9 0.0 6.4 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 ORX95442.1 - 1.9e-11 43.1 0.1 0.0065 16.6 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 ORX95442.1 - 3.2e-06 27.5 0.1 0.25 11.9 0.1 4.0 3 2 2 5 5 5 2 HEAT-like repeat Arm PF00514.23 ORX95442.1 - 9.3e-06 25.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat DUF2456 PF10445.9 ORX95443.1 - 2.9e-14 52.9 5.7 8.8e-14 51.4 5.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2456) DUF4282 PF14110.6 ORX95443.1 - 0.44 11.3 0.1 0.44 11.3 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) 6PF2K PF01591.18 ORX95444.1 - 4.4e-81 271.4 0.0 5.7e-81 271.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORX95444.1 - 1.2e-25 90.3 0.0 4.1e-25 88.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORX95444.1 - 0.00013 22.2 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain His_Phos_2 PF00328.22 ORX95444.1 - 0.0036 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA_17 PF13207.6 ORX95444.1 - 0.17 12.3 0.0 0.68 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Glyco_transf_25 PF01755.17 ORX95445.1 - 0.084 12.7 1.7 5.2 6.9 1.7 2.2 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) GST_N_3 PF13417.6 ORX95449.1 - 6.5e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX95449.1 - 2.2e-09 37.5 0.1 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX95449.1 - 2.6e-09 37.2 0.1 8.4e-09 35.5 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX95449.1 - 3.8e-07 30.3 0.0 1.1e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORX95449.1 - 2.2e-06 27.8 2.3 2.1e-05 24.6 0.1 2.4 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX95449.1 - 5.5e-05 23.1 0.0 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX95449.1 - 0.0019 18.8 0.0 0.0055 17.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 ORX95450.1 - 1.7e-26 93.0 40.7 9.2e-21 74.1 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORX95450.1 - 4.1e-06 25.5 15.5 5e-06 25.2 14.2 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ORX95450.1 - 0.07 11.4 10.0 0.016 13.6 1.3 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1746 PF08508.10 ORX95450.1 - 1.6 9.1 5.9 0.86 10.0 0.4 2.7 3 0 0 3 3 3 0 Fungal domain of unknown function (DUF1746) Pyr_redox_2 PF07992.14 ORX95451.1 - 2.2e-23 82.9 0.0 3.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX95451.1 - 6.7e-10 39.4 0.0 1.8e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORX95451.1 - 0.0019 17.4 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORX95451.1 - 0.005 16.5 0.1 1.9 8.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORX95451.1 - 0.014 14.3 0.0 0.61 8.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ORX95451.1 - 0.11 11.5 0.1 1.8 7.5 0.0 2.1 1 1 1 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORX95451.1 - 0.13 11.5 0.1 0.22 10.7 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX95451.1 - 0.29 11.1 1.0 4.4 7.3 0.0 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding Acetyltransf_1 PF00583.25 ORX95452.1 - 0.057 13.6 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Mg_trans_NIPA PF05653.14 ORX95453.1 - 3.2e-12 46.2 14.4 5.1e-12 45.5 14.4 1.3 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORX95453.1 - 3.8e-07 30.3 20.8 0.00066 19.9 0.7 2.7 2 1 1 3 3 3 2 EamA-like transporter family Polysacc_synt_C PF14667.6 ORX95453.1 - 0.017 15.2 13.5 0.017 15.2 13.5 2.9 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF3180 PF11377.8 ORX95453.1 - 0.025 14.7 8.9 0.58 10.3 0.2 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3180) UPF0370 PF13980.6 ORX95453.1 - 0.037 14.1 0.1 0.037 14.1 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) DUF4381 PF14316.6 ORX95453.1 - 0.1 12.8 0.8 0.28 11.4 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Spore_YhaL PF14147.6 ORX95453.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.1 3 0 0 3 3 3 0 Sporulation protein YhaL Neurensin PF14927.6 ORX95453.1 - 0.56 9.9 4.1 12 5.7 1.2 2.9 2 1 0 2 2 2 0 Neurensin NiFe_hyd_3_EhaA PF17367.2 ORX95453.1 - 5.3 7.2 8.2 0.25 11.5 0.5 2.8 4 0 0 4 4 4 0 NiFe-hydrogenase-type-3 Eha complex subunit A Aa_trans PF01490.18 ORX95454.1 - 2.9e-77 260.1 32.2 3.5e-77 259.8 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPT_ssu-like PF11779.8 ORX95454.1 - 2.3 7.9 8.4 2.7 7.7 0.1 4.2 3 1 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like RET_CLD3 PF17812.1 ORX95455.1 - 0.14 12.4 2.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 RET Cadherin like domain 3 Exonuc_VII_L PF02601.15 ORX95455.1 - 2.1 7.9 15.1 1.8 8.0 14.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fasciclin PF02469.22 ORX95456.1 - 4.9e-22 78.5 0.0 2.1e-21 76.4 0.0 1.8 1 1 0 1 1 1 1 Fasciclin domain DJ-1_PfpI PF01965.24 ORX95457.1 - 8.4e-23 81.0 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 ORX95457.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Oxidored_q6 PF01058.22 ORX95457.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit GATase_5 PF13507.6 ORX95457.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain RAI16-like PF10257.9 ORX95459.1 - 5.4e-63 213.0 0.6 7.4e-63 212.6 0.6 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Fasciclin PF02469.22 ORX95460.1 - 4.9e-22 78.5 0.0 2.1e-21 76.4 0.0 1.8 1 1 0 1 1 1 1 Fasciclin domain GSHPx PF00255.19 ORX95461.1 - 9.8e-45 150.6 0.2 1.3e-44 150.2 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORX95461.1 - 0.00011 22.1 0.1 0.0004 20.3 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.6 ORX95461.1 - 0.0046 17.4 0.0 0.018 15.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.10 ORX95461.1 - 0.0049 16.6 0.1 0.032 13.9 0.1 1.9 1 1 0 1 1 1 1 Redoxin HLH PF00010.26 ORX95462.1 - 1.5e-19 69.7 1.8 1.9e-18 66.2 2.8 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DSPc PF00782.20 ORX95463.1 - 8.5e-34 116.2 0.0 1.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX95463.1 - 0.00044 19.9 0.0 0.00058 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORX95463.1 - 0.004 17.3 0.0 0.0054 16.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF4219 PF13961.6 ORX95464.1 - 3.6e-07 29.7 2.3 1.2e-06 28.0 2.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 ORX95464.1 - 0.0008 19.1 0.3 0.0011 18.7 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ras PF00071.22 ORX95465.1 - 1.2e-55 187.5 0.0 1.4e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95465.1 - 4.3e-20 72.1 0.0 1.1e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95465.1 - 1.9e-08 33.9 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX95465.1 - 6.2e-08 32.7 0.0 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORX95465.1 - 0.00016 21.3 0.0 0.0005 19.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ORX95465.1 - 0.0049 16.8 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORX95465.1 - 0.0093 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase pPIWI_RE_Y PF18156.1 ORX95465.1 - 0.016 15.6 0.1 0.063 13.7 0.0 1.8 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y DUF3721 PF12518.8 ORX95465.1 - 0.021 14.6 0.2 0.044 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function baeRF_family3 PF18845.1 ORX95465.1 - 0.041 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 MeaB PF03308.16 ORX95465.1 - 0.046 12.7 0.2 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4047 PF13256.6 ORX95465.1 - 0.1 12.8 1.3 0.15 12.3 0.2 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) FeoB_N PF02421.18 ORX95465.1 - 0.11 12.0 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Ribosomal_L13e PF01294.18 ORX95466.1 - 2.9e-81 271.6 8.0 4e-81 271.2 8.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L32e PF01655.18 ORX95467.1 - 1.7e-26 92.7 2.0 3.8e-26 91.6 2.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L32 DUF1856 PF08983.10 ORX95469.1 - 0.2 11.9 0.1 0.51 10.6 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1856) GST_C_3 PF14497.6 ORX95480.1 - 9.1e-14 51.5 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX95480.1 - 2.2e-07 31.0 0.0 3.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX95480.1 - 0.0001 22.6 0.0 0.0003 21.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX95480.1 - 0.0026 17.7 0.0 0.026 14.6 0.0 2.5 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORX95480.1 - 0.019 15.5 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX95480.1 - 0.028 14.8 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX95480.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-C2H2 PF00096.26 ORX95481.1 - 9.1e-08 32.2 24.1 0.00029 21.1 1.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX95481.1 - 0.00031 21.0 1.6 0.00031 21.0 1.6 3.8 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX95481.1 - 0.0014 19.3 23.9 0.011 16.5 1.1 3.7 5 0 0 5 5 5 2 C2H2-type zinc finger Vps39_2 PF10367.9 ORX95481.1 - 0.0081 16.6 0.2 0.016 15.7 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C2H2_6 PF13912.6 ORX95481.1 - 0.018 15.0 4.0 0.018 15.0 4.0 4.4 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95481.1 - 0.026 14.8 5.7 0.18 12.2 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX95481.1 - 0.052 13.9 1.3 0.052 13.9 1.3 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HSBP1 PF06825.12 ORX95483.1 - 1.4e-08 34.5 2.8 2.2e-08 33.8 2.6 1.5 1 1 0 1 1 1 1 Heat shock factor binding protein 1 DUF5344 PF17279.2 ORX95483.1 - 0.0027 18.3 1.7 1.1 9.9 0.2 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5344) FliD_C PF07195.12 ORX95483.1 - 0.012 15.0 0.7 0.015 14.7 0.7 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF1515 PF07439.11 ORX95483.1 - 0.021 14.9 0.6 0.024 14.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Streptin-Immun PF11083.8 ORX95483.1 - 0.022 15.1 0.6 0.028 14.8 0.6 1.1 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein HsbA PF12296.8 ORX95483.1 - 0.024 15.0 0.2 5.1 7.5 0.1 2.1 1 1 1 2 2 2 0 Hydrophobic surface binding protein A NPV_P10 PF05531.12 ORX95483.1 - 0.028 14.9 0.9 0.093 13.2 0.9 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 ORX95483.1 - 0.03 14.6 1.4 0.13 12.5 1.0 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain Flagellin_C PF00700.21 ORX95483.1 - 0.039 14.3 0.1 0.047 14.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF1664 PF07889.12 ORX95483.1 - 0.043 13.9 0.6 0.05 13.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 ORX95483.1 - 0.053 13.9 0.8 0.069 13.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ACCA PF03255.14 ORX95483.1 - 0.055 13.3 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LPP PF04728.13 ORX95483.1 - 0.077 13.4 1.6 0.44 11.0 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper YvrJ PF12841.7 ORX95483.1 - 0.11 12.1 0.4 13 5.4 0.1 2.2 2 0 0 2 2 2 0 YvrJ protein family Matrilin_ccoil PF10393.9 ORX95483.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.6 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin XhlA PF10779.9 ORX95483.1 - 0.19 11.9 2.1 0.3 11.3 2.1 1.3 1 1 0 1 1 1 0 Haemolysin XhlA Ribosomal_S17 PF00366.20 ORX95484.1 - 1.3e-26 92.5 2.6 1.5e-26 92.3 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 P19Arf_N PF07392.12 ORX95484.1 - 0.32 11.5 0.1 0.32 11.5 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus zf-C2H2 PF00096.26 ORX95485.1 - 2.5e-11 43.4 17.4 1.4e-05 25.3 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95485.1 - 6.2e-08 32.8 15.2 0.0005 20.7 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX95485.1 - 2.4e-07 30.8 13.8 2.4e-05 24.6 1.2 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX95485.1 - 3.1e-06 27.0 12.5 2.2e-05 24.3 4.3 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX95485.1 - 0.0008 19.7 0.9 0.0008 19.7 0.9 2.3 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX95485.1 - 0.0096 16.2 6.1 0.012 15.9 0.6 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORX95485.1 - 1.6 9.2 6.4 1.8 9.1 2.1 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 ORX95485.1 - 1.9 8.4 9.2 0.62 10.0 2.6 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2 PF00096.26 ORX95486.1 - 2.2e-12 46.7 12.7 1.8e-06 28.1 3.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95486.1 - 3e-09 36.9 10.5 0.00011 22.7 2.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX95486.1 - 1.3e-08 34.9 11.6 3.3e-05 24.1 0.6 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX95486.1 - 3.4e-08 33.3 4.5 0.00036 20.4 0.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95486.1 - 0.00016 21.8 0.3 0.00016 21.8 0.3 2.7 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX95486.1 - 0.00019 21.7 0.2 0.00019 21.7 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORX95486.1 - 0.011 15.7 6.7 0.71 9.8 1.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 ORX95486.1 - 0.057 14.1 0.2 0.19 12.4 0.1 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 ORX95486.1 - 0.068 13.5 2.4 0.18 12.2 0.3 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 ORX95486.1 - 0.25 11.3 4.9 0.44 10.5 0.5 2.3 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Arrestin_N PF00339.29 ORX95488.1 - 3.8e-07 30.3 0.2 3.7e-06 27.1 0.1 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX95488.1 - 0.00015 21.5 0.0 0.00046 19.9 0.0 1.7 1 1 0 1 1 1 1 Arrestin_N terminal like TPR_2 PF07719.17 ORX95490.1 - 1.4e-35 118.5 3.2 7e-05 22.6 0.0 7.4 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95490.1 - 2.6e-34 115.6 2.9 2.6e-06 27.0 0.0 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORX95490.1 - 4e-25 85.9 1.4 0.00028 20.9 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORX95490.1 - 9e-23 80.6 1.1 8.7e-06 26.2 0.2 5.8 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORX95490.1 - 1.8e-22 79.7 0.0 0.00065 20.3 0.0 5.5 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORX95490.1 - 2.2e-19 68.5 1.5 0.025 15.4 0.0 6.6 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORX95490.1 - 3.2e-19 68.3 2.3 4e-05 23.2 0.0 6.7 3 2 5 8 8 8 4 TPR repeat TPR_12 PF13424.6 ORX95490.1 - 8.3e-19 67.7 0.6 1.4e-05 25.3 0.0 5.8 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 ORX95490.1 - 3e-13 49.7 0.0 0.051 13.7 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX95490.1 - 2.4e-12 46.9 3.1 0.0011 19.1 0.0 4.3 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORX95490.1 - 3.1e-12 45.6 0.7 0.22 11.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORX95490.1 - 4.4e-12 45.5 1.3 0.056 13.8 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORX95490.1 - 4.8e-12 45.7 4.3 0.5 11.1 0.1 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORX95490.1 - 5.8e-08 32.3 0.5 0.096 11.9 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX95490.1 - 5.6e-06 26.0 0.3 0.011 15.1 0.0 3.4 2 1 1 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 ORX95490.1 - 0.00044 20.0 0.0 0.012 15.3 0.0 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 ORX95490.1 - 0.00084 19.8 1.3 1.8 9.0 0.0 3.6 2 1 1 3 3 3 2 Bacterial transcriptional activator domain MIT PF04212.18 ORX95490.1 - 0.0072 16.4 2.5 8.3 6.6 0.0 5.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 ORX95490.1 - 0.0082 15.6 0.9 1.5 8.2 0.0 3.3 2 2 1 3 3 3 1 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 ORX95490.1 - 0.0085 15.5 0.1 0.55 9.6 0.1 2.7 1 1 1 3 3 3 1 Coatomer epsilon subunit TPR_10 PF13374.6 ORX95490.1 - 0.0086 15.9 0.8 1e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 ORX95490.1 - 0.025 13.6 0.1 0.62 9.0 0.0 2.1 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Foie-gras_1 PF11817.8 ORX95490.1 - 0.071 12.7 0.7 46 3.5 0.1 3.2 3 0 0 3 3 3 0 Foie gras liver health family 1 NARP1 PF12569.8 ORX95490.1 - 0.096 11.6 1.4 0.84 8.5 0.1 2.7 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 SPRY PF00622.28 ORX95491.1 - 3.6e-19 69.0 0.1 6.1e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 ORX95491.1 - 3.5e-10 39.6 7.2 5.8e-10 38.9 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX95491.1 - 0.0022 17.8 7.7 0.0044 16.9 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HEAT_EZ PF13513.6 ORX95491.1 - 0.034 14.6 0.1 0.09 13.3 0.0 1.7 2 0 0 2 2 2 0 HEAT-like repeat zf-RING_2 PF13639.6 ORX95491.1 - 0.36 11.2 9.7 0.72 10.2 9.7 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 ORX95491.1 - 1.3 9.0 8.7 2.8 8.0 8.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2321 PF10083.9 ORX95491.1 - 3.2 7.4 6.2 0.68 9.6 1.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ABC_membrane PF00664.23 ORX95493.1 - 5.4e-100 334.6 24.0 7.1e-51 173.5 9.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX95493.1 - 9.9e-71 236.6 0.0 1.5e-35 122.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX95493.1 - 7.4e-16 58.2 4.6 1.2e-05 24.8 0.5 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX95493.1 - 9.1e-09 34.9 0.2 0.0012 18.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORX95493.1 - 2e-08 34.6 0.1 0.0014 18.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORX95493.1 - 3.1e-08 34.2 4.5 0.0018 18.7 0.3 3.8 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORX95493.1 - 7.9e-08 32.4 0.0 0.0041 17.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 ORX95493.1 - 5.6e-07 29.0 0.1 0.033 13.5 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin ABC_ATPase PF09818.9 ORX95493.1 - 2.6e-06 26.5 2.0 0.0066 15.3 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 ORX95493.1 - 5.3e-06 26.3 1.0 0.22 11.2 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 ORX95493.1 - 1.1e-05 25.9 0.4 0.23 11.9 0.0 4.2 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORX95493.1 - 9.3e-05 23.0 0.0 0.92 10.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORX95493.1 - 0.0001 22.3 0.4 1.2 9.2 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 ORX95493.1 - 0.00012 22.0 0.1 0.75 9.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 ORX95493.1 - 0.00012 21.3 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit Rad17 PF03215.15 ORX95493.1 - 0.00014 21.8 0.0 0.0061 16.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 ORX95493.1 - 0.00023 21.3 0.0 0.54 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORX95493.1 - 0.00039 21.0 0.0 0.39 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ORX95493.1 - 0.00061 19.6 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 ORX95493.1 - 0.001 18.7 0.0 0.44 10.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 ORX95493.1 - 0.0019 17.8 0.1 4.7 6.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 ORX95493.1 - 0.0041 17.2 0.3 1.8 8.6 0.0 3.7 4 0 0 4 4 3 1 Helicase HerA, central domain DUF815 PF05673.13 ORX95493.1 - 0.0076 15.4 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORX95493.1 - 0.0083 15.3 0.1 2.5 7.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 ORX95493.1 - 0.0084 16.0 0.0 3.9 7.3 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase PRK PF00485.18 ORX95493.1 - 0.01 15.6 0.0 5 6.8 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 ORX95493.1 - 0.011 15.8 0.0 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 ORX95493.1 - 0.012 15.3 0.0 2.3 7.8 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 ORX95493.1 - 0.015 15.7 0.0 6.6 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.6 ORX95493.1 - 0.019 15.2 11.6 0.63 10.3 0.2 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ORX95493.1 - 0.024 14.4 0.0 8 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORX95493.1 - 0.029 14.6 0.3 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORX95493.1 - 0.038 13.9 0.1 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 ORX95493.1 - 0.043 13.2 0.1 11 5.4 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein Sigma54_activat PF00158.26 ORX95493.1 - 0.054 13.2 0.1 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 ORX95493.1 - 0.059 12.6 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain IstB_IS21 PF01695.17 ORX95493.1 - 0.092 12.5 5.6 15 5.3 0.0 4.6 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_17 PF13207.6 ORX95493.1 - 0.11 13.0 0.3 30 5.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain RepB-RCR_reg PF10723.9 ORX95493.1 - 0.11 12.5 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Replication regulatory protein RepB tRNA_lig_kinase PF08303.11 ORX95493.1 - 0.13 12.4 0.0 7 6.7 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_PrkA PF08298.11 ORX95493.1 - 0.17 10.8 0.0 13 4.6 0.0 2.4 2 0 0 2 2 2 0 PrkA AAA domain SRF-TF PF00319.18 ORX95516.1 - 4.9e-22 77.2 0.1 6.3e-22 76.8 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) pEK499_p136 PF18736.1 ORX95516.1 - 0.083 12.5 0.1 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 HEPN pEK499 p136 F-box PF00646.33 ORX95517.1 - 5.7e-05 22.9 0.9 0.00016 21.5 0.9 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX95517.1 - 0.0015 18.4 1.0 0.0015 18.4 1.0 2.2 2 0 0 2 2 2 1 F-box-like TniQ PF06527.11 ORX95517.1 - 0.0034 18.1 0.7 0.01 16.5 0.7 1.8 1 0 0 1 1 1 1 TniQ XPA_C PF05181.12 ORX95517.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 XPA protein C-terminus F-box_4 PF15966.5 ORX95517.1 - 0.047 13.6 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 F-box CsbD PF05532.12 ORX95518.1 - 2.2e-16 59.5 14.6 4.5e-09 36.1 3.9 2.2 1 1 1 2 2 2 2 CsbD-like Apolipoprotein PF01442.18 ORX95518.1 - 0.025 14.5 1.8 0.05 13.5 1.8 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4148 PF13663.6 ORX95518.1 - 0.088 13.0 1.6 0.13 12.5 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Trs65 PF12735.7 ORX95520.1 - 7.1e-30 104.5 0.5 1.1e-29 103.8 0.5 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 PXA PF02194.15 ORX95521.1 - 4.8e-48 163.5 1.4 4.8e-48 163.5 1.4 1.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 ORX95521.1 - 4.4e-12 46.6 0.0 1.7e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal Rad52_Rad22 PF04098.15 ORX95522.1 - 5.1e-51 172.6 0.0 5.9e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PQ-loop PF04193.14 ORX95523.1 - 6.6e-18 64.2 8.7 3.1e-12 46.1 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 ORX95523.1 - 1e-05 26.4 7.3 1.6e-05 25.7 7.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Adeno_GP19K PF04881.13 ORX95523.1 - 0.044 13.8 0.1 0.044 13.8 0.1 1.6 2 0 0 2 2 2 0 Adenovirus GP19K RRM_1 PF00076.22 ORX95524.1 - 1.2e-34 117.9 1.1 9.7e-14 51.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX95524.1 - 3.9e-06 26.9 0.0 0.0051 16.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 ORX95524.1 - 0.00011 22.0 0.0 0.002 18.0 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORX95524.1 - 0.013 15.4 0.0 0.61 10.1 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Spo7_2_N PF15407.6 ORX95524.1 - 0.085 12.5 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 Rad4 PF03835.15 ORX95525.1 - 8.1e-29 100.2 1.5 8.1e-29 100.2 1.5 2.6 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 ORX95525.1 - 3e-28 98.0 0.3 6e-28 97.1 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 ORX95525.1 - 7.9e-21 73.6 0.0 2.4e-19 68.9 0.0 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 ORX95525.1 - 2.1e-17 63.8 0.6 2.1e-17 63.8 0.6 3.6 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 ORX95525.1 - 1.4e-05 25.5 0.0 4.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily Ras PF00071.22 ORX95526.1 - 2.2e-50 170.4 0.0 2.7e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95526.1 - 1.5e-20 73.6 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95526.1 - 3.1e-07 30.0 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX95526.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORX95526.1 - 0.095 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Cyclin PF08613.11 ORX95528.1 - 1.9e-11 44.6 0.2 2.3e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX95528.1 - 3.2e-06 26.9 0.3 3.9e-06 26.6 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Folate_carrier PF01770.18 ORX95530.1 - 0.0033 16.2 4.1 0.0045 15.8 4.1 1.3 1 0 0 1 1 1 1 Reduced folate carrier CMS1 PF14617.6 ORX95530.1 - 0.0042 16.5 1.8 0.0076 15.6 1.8 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Peptidase_S64 PF08192.11 ORX95530.1 - 0.0044 15.6 0.6 0.005 15.4 0.6 1.3 1 0 0 1 1 1 1 Peptidase family S64 ATG22 PF11700.8 ORX95530.1 - 0.012 14.3 0.0 0.031 12.9 0.0 1.6 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF4614 PF15391.6 ORX95530.1 - 0.014 15.4 11.6 0.014 15.4 10.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) Apis_Csd PF11671.8 ORX95530.1 - 0.17 11.9 3.5 0.41 10.7 3.5 1.8 1 0 0 1 1 1 0 Complementary sex determiner protein OATP PF03137.20 ORX95530.1 - 0.21 9.8 0.7 0.34 9.1 0.7 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ALMT PF11744.8 ORX95530.1 - 0.22 10.3 7.8 0.38 9.5 7.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 ORX95530.1 - 0.22 10.4 1.0 0.33 9.8 1.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 ORX95530.1 - 0.25 10.1 7.6 0.42 9.3 7.6 1.4 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 ORX95530.1 - 0.33 9.4 8.3 0.5 8.7 8.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF702 PF05142.12 ORX95530.1 - 0.36 11.3 5.2 0.98 9.9 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF702) AAA_11 PF13086.6 ORX95530.1 - 0.38 10.5 9.2 0.42 10.4 7.7 1.7 2 0 0 2 2 2 0 AAA domain DUF913 PF06025.12 ORX95530.1 - 0.61 9.0 6.2 1.2 8.1 6.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 ORX95530.1 - 1.1 9.4 9.5 0.11 12.7 4.7 1.8 2 0 0 2 2 2 0 DDHD domain FAM176 PF14851.6 ORX95530.1 - 1.7 8.3 10.9 0.29 10.8 6.8 1.9 2 0 0 2 2 1 0 FAM176 family Nucleo_P87 PF07267.11 ORX95530.1 - 1.9 7.2 13.5 3.5 6.4 13.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPL5 PF18168.1 ORX95530.1 - 2 7.6 7.5 0.47 9.7 4.2 1.6 2 0 0 2 2 2 0 Prim-pol family 5 EIIBC-GUT_N PF03612.14 ORX95530.1 - 2 8.1 5.5 5.4 6.7 5.5 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_polI_A34 PF08208.11 ORX95530.1 - 2.2 8.3 18.9 5.4 7.0 18.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4820 PF16091.5 ORX95530.1 - 2.8 7.3 9.8 6.2 6.1 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Afi1 PF07792.12 ORX95530.1 - 3 8.3 9.0 9.2 6.8 9.0 1.8 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking LicD PF04991.13 ORX95530.1 - 6.2 6.9 8.0 2.8 8.0 5.6 1.7 2 0 0 2 2 1 0 LicD family DUF2514 PF10721.9 ORX95530.1 - 8.8 6.3 14.3 2.1 8.4 7.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Amidohydro_1 PF01979.20 ORX95532.1 - 1.5e-72 244.8 0.0 1.8e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX95532.1 - 1.2e-10 41.5 0.0 5.5e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Sulfate_transp PF00916.20 ORX95553.1 - 1.3e-99 333.5 24.8 1.6e-99 333.2 24.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX95553.1 - 9.3e-13 47.9 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORX95553.1 - 0.0021 18.4 0.0 0.0064 16.8 0.0 1.8 1 0 0 1 1 1 1 STAS domain DUF2104 PF09877.9 ORX95553.1 - 0.0043 17.3 0.3 0.021 15.1 0.3 2.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2104) Trehalose_recp PF06151.13 ORX95553.1 - 0.059 12.0 0.1 0.096 11.3 0.1 1.3 1 0 0 1 1 1 0 Trehalose receptor NAP PF00956.18 ORX95553.1 - 0.073 12.2 0.0 0.2 10.8 0.1 1.6 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Ribosomal_L34e PF01199.18 ORX95554.1 - 1.6e-46 156.5 4.0 2.2e-46 156.1 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.6 ORX95554.1 - 0.14 12.7 3.8 0.56 10.8 3.8 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Rep_fac-A_3 PF08661.11 ORX95555.1 - 6.4e-30 103.6 0.1 7.1e-30 103.5 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 PilP PF04351.13 ORX95555.1 - 0.059 13.3 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilP TFIIA PF03153.13 ORX95556.1 - 2.2e-54 186.1 13.8 4.7e-38 132.3 7.4 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Aminotran_5 PF00266.19 ORX95557.1 - 7.9e-18 64.5 0.0 1e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORX95557.1 - 0.0053 15.3 0.0 0.0069 15.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Med9 PF07544.13 ORX95558.1 - 0.00029 20.9 2.8 0.00032 20.7 2.8 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 ORX95558.1 - 0.046 14.0 1.4 0.052 13.8 1.4 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Proteasome PF00227.26 ORX95559.1 - 3.6e-45 153.8 0.6 4.1e-45 153.6 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit BTB PF00651.31 ORX95560.1 - 2.1e-05 24.7 0.2 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Band_7 PF01145.25 ORX95562.1 - 9.4e-22 77.9 4.1 1.3e-21 77.4 4.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Epimerase PF01370.21 ORX95563.1 - 1.1e-20 74.2 0.1 1.4e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX95563.1 - 1.8e-10 40.4 0.0 2.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORX95563.1 - 2.3e-10 39.9 0.1 1.1e-09 37.8 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORX95563.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ORX95563.1 - 0.015 14.8 0.0 0.5 9.8 0.0 2.5 3 0 0 3 3 3 0 short chain dehydrogenase Fungal_trans PF04082.18 ORX95564.1 - 9.1e-35 120.0 0.7 1.4e-34 119.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX95565.1 - 1.3e-11 44.4 13.0 1.7e-11 44.1 13.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cse1 PF08506.10 ORX95566.1 - 1.2e-11 44.1 0.1 1.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Cse1 HEAT_EZ PF13513.6 ORX95566.1 - 9.3e-07 29.2 2.8 0.058 13.9 0.0 5.6 6 0 0 6 6 6 2 HEAT-like repeat API5 PF05918.11 ORX95566.1 - 0.0039 16.1 0.0 0.77 8.5 0.0 2.2 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) Sec7_N PF12783.7 ORX95566.1 - 0.011 15.7 0.4 0.11 12.4 0.0 3.0 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Mito_carr PF00153.27 ORX95567.1 - 1.5e-64 214.0 2.9 9.5e-23 80.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 ORX95567.1 - 0.66 10.1 2.6 0.63 10.2 0.2 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif PH PF00169.29 ORX95568.1 - 1.4e-08 35.1 1.1 1.8e-08 34.8 1.1 1.1 1 0 0 1 1 1 1 PH domain PBD PF00786.28 ORX95568.1 - 4.5e-06 26.9 2.0 5.2e-06 26.7 1.1 1.6 2 0 0 2 2 2 1 P21-Rho-binding domain Nucleopor_Nup85 PF07575.13 ORX95569.1 - 2.9e-126 422.3 3.3 3.6e-126 422.0 3.3 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin Nup84_Nup100 PF04121.13 ORX95569.1 - 0.00035 18.8 0.2 0.00076 17.7 0.1 1.6 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 Pox_VLTF3 PF04947.14 ORX95569.1 - 0.15 11.8 1.3 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like TPR_16 PF13432.6 ORX95569.1 - 0.24 12.1 3.3 5.5 7.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX95569.1 - 9.1 6.7 9.0 18 5.7 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RibD_C PF01872.17 ORX95570.1 - 7.9e-38 130.3 0.0 9.7e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Chitin_synth_2 PF03142.15 ORX95572.1 - 3.1e-284 943.5 0.5 4e-284 943.1 0.5 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX95572.1 - 4e-13 49.8 0.0 3.8e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX95572.1 - 4.9e-12 46.2 5.7 4.9e-12 46.2 5.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX95572.1 - 5.5e-05 22.7 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX95572.1 - 0.0032 17.3 0.0 0.095 12.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1828 PF08861.10 ORX95572.1 - 0.12 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF4229 PF14012.6 ORX95572.1 - 2.8 8.1 11.1 15 5.8 6.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Xan_ur_permease PF00860.20 ORX95573.1 - 2e-63 214.4 35.7 4e-62 210.1 35.7 2.1 1 1 0 1 1 1 1 Permease family OPT PF03169.15 ORX95574.1 - 1e-143 480.2 43.4 1.2e-143 480.0 43.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CIA30 PF08547.12 ORX95575.1 - 1.2e-45 155.4 0.0 1.3e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 ORX95575.1 - 0.0079 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain PAS_3 PF08447.12 ORX95576.1 - 1.1e-32 112.2 2.6 1.9e-15 56.9 0.8 2.9 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 ORX95576.1 - 1.6e-29 102.7 0.1 5.3e-29 101.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORX95576.1 - 4.4e-22 78.4 0.6 3.3e-21 75.6 0.1 2.8 3 0 0 3 3 2 1 Response regulator receiver domain AAA_16 PF13191.6 ORX95576.1 - 1.3e-19 71.2 0.0 5.5e-19 69.2 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain HisKA PF00512.25 ORX95576.1 - 9.8e-17 60.8 0.0 6.6e-16 58.1 0.0 2.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ORX95576.1 - 5e-15 55.6 0.0 3.5e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORX95576.1 - 5.6e-13 49.1 0.0 2.1e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORX95576.1 - 7e-11 42.1 0.0 7.5e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 PAS fold NACHT PF05729.12 ORX95576.1 - 2.3e-07 30.9 0.0 7.3e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 ORX95576.1 - 0.0029 16.8 0.9 0.018 14.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain GAF_3 PF13492.6 ORX95576.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.6 ORX95576.1 - 0.0057 16.9 0.5 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain GAF_2 PF13185.6 ORX95576.1 - 0.0061 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain ATPase_2 PF01637.18 ORX95576.1 - 0.031 14.2 0.3 0.1 12.5 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea HATPase_c_3 PF13589.6 ORX95576.1 - 0.032 14.0 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RsgA_GTPase PF03193.16 ORX95576.1 - 0.038 13.9 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 ORX95576.1 - 0.046 13.4 1.3 13 5.4 0.1 3.2 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 ORX95576.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PAS_8 PF13188.7 ORX95576.1 - 0.079 13.0 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 PAS domain ABC_tran PF00005.27 ORX95576.1 - 0.085 13.4 0.1 0.62 10.6 0.0 2.6 3 0 0 3 3 1 0 ABC transporter NTPase_1 PF03266.15 ORX95576.1 - 0.1 12.5 0.8 0.38 10.7 0.1 2.4 3 0 0 3 3 2 0 NTPase IstB_IS21 PF01695.17 ORX95576.1 - 0.1 12.3 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein APG6 PF04111.12 ORX95576.1 - 0.13 12.2 0.5 2.1 8.2 0.1 2.9 3 0 0 3 3 3 0 Apg6 BARA domain GAF PF01590.26 ORX95576.1 - 0.13 12.9 0.0 0.86 10.2 0.0 2.4 2 0 0 2 2 2 0 GAF domain RPW8 PF05659.11 ORX95576.1 - 0.18 11.5 1.4 2.8 7.6 0.1 2.8 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Pox_D5 PF03288.16 ORX95576.1 - 1 9.9 5.9 3.1 8.4 0.1 3.4 3 0 0 3 3 3 0 Poxvirus D5 protein-like DUF21 PF01595.20 ORX95577.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Chs7 PF12271.8 ORX95578.1 - 2.2e-101 339.0 18.5 2.8e-101 338.7 18.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Chs7 PF12271.8 ORX95579.1 - 2.2e-107 358.7 17.8 2.5e-107 358.5 17.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Isochorismatase PF00857.20 ORX95580.1 - 3.5e-28 98.9 0.1 6.2e-28 98.2 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF5079 PF16882.5 ORX95581.1 - 0.018 14.9 1.1 0.018 14.9 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) ACOX PF01756.19 ORX95582.1 - 7.5e-14 51.7 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORX95582.1 - 8.4e-14 51.5 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORX95582.1 - 5.6e-07 29.9 0.0 9.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ORX95582.1 - 0.055 14.0 0.0 0.095 13.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF1349 PF07081.11 ORX95583.1 - 0.071 12.8 0.2 0.18 11.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1349) Abhydrolase_1 PF00561.20 ORX95584.1 - 2.2e-31 109.4 0.5 4.3e-31 108.5 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX95584.1 - 7.5e-20 72.5 0.5 1e-19 72.0 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX95584.1 - 9e-13 48.0 0.0 7.2e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ORX95584.1 - 0.00013 21.6 0.0 0.0049 16.5 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.14 ORX95584.1 - 0.0074 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 ORX95584.1 - 0.017 14.2 0.0 0.037 13.0 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_2 PF02230.16 ORX95584.1 - 0.027 14.3 0.0 8 6.2 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 ORX95584.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 ORX95584.1 - 0.15 11.8 0.0 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family DASH_Dam1 PF08653.10 ORX95585.1 - 0.49 10.2 2.0 1 9.2 0.7 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Spc7 PF08317.11 ORX95585.1 - 2.4 7.0 29.1 1.3 7.8 2.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.12 ORX95585.1 - 3.8 7.9 20.7 3 8.2 4.1 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.6 ORX95585.1 - 6.7 6.3 41.9 1.1 8.9 22.4 3.4 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease RRM_2 PF04059.12 ORX95586.1 - 4e-27 94.3 2.3 4.9e-27 94.0 1.0 1.9 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 ORX95586.1 - 2.7e-05 23.9 0.0 0.77 9.6 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 ORX95587.1 - 5.4e-67 225.9 0.0 6.6e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95587.1 - 6e-51 173.2 0.0 8e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX95587.1 - 1.5e-05 24.5 0.0 0.032 13.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORX95587.1 - 0.0034 16.2 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Aa_trans PF01490.18 ORX95588.1 - 6.7e-66 222.7 23.3 6.7e-66 222.7 23.3 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX95588.1 - 6.9e-05 22.0 13.5 0.00016 20.8 13.5 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 ORX95589.1 - 3e-59 200.8 25.4 4.8e-59 200.1 25.4 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORX95589.1 - 0.00028 20.1 13.9 0.00028 20.1 13.9 1.8 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family SLC3A2_N PF16028.5 ORX95589.1 - 0.09 12.3 0.0 0.33 10.5 0.0 1.9 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus SRF-TF PF00319.18 ORX95590.1 - 6.4e-17 60.8 0.2 1e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3164 PF11363.8 ORX95591.1 - 0.015 15.0 0.5 0.15 11.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3164) Ribosomal_S27e PF01667.17 ORX95592.1 - 1.6e-29 101.4 4.9 2.1e-29 101.0 4.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ORX95592.1 - 0.19 11.3 3.2 0.32 10.5 3.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding ALO PF04030.14 ORX95594.1 - 3.5e-24 86.0 0.0 1.7e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ORX95594.1 - 2e-22 79.4 0.4 4.2e-22 78.4 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Alpha_GJ PF03229.13 ORX95610.1 - 0.12 12.9 3.5 0.19 12.3 3.5 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Chorismate_bind PF00425.18 ORX95610.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 chorismate binding enzyme Mito_carr PF00153.27 ORX95611.1 - 4.1e-22 77.9 0.0 2e-10 40.5 0.0 4.2 3 2 0 3 3 3 3 Mitochondrial carrier protein Lipase_3 PF01764.25 ORX95612.1 - 1.2e-08 35.0 0.0 2.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORX95612.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORX95612.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 ORX95612.1 - 0.38 10.3 0.9 1.6 8.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) PPR_2 PF13041.6 ORX95614.1 - 2.9e-87 286.7 27.4 3.9e-11 43.0 0.0 13.2 4 3 10 14 14 14 12 PPR repeat family PPR_3 PF13812.6 ORX95614.1 - 6.7e-68 224.7 12.0 9.9e-12 44.8 0.0 9.5 6 3 7 13 13 12 10 Pentatricopeptide repeat domain PPR PF01535.20 ORX95614.1 - 9.8e-54 175.9 26.3 6.9e-06 26.0 0.0 14.3 15 0 0 15 15 14 10 PPR repeat PPR_1 PF12854.7 ORX95614.1 - 4.2e-49 163.9 7.2 3.5e-07 29.8 0.0 12.8 13 0 0 13 13 13 10 PPR repeat PPR_long PF17177.4 ORX95614.1 - 4.3e-39 134.1 0.5 2.4e-10 40.2 0.0 5.6 1 1 4 6 6 6 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX95614.1 - 2.7e-08 34.2 3.0 4.4 7.7 0.0 7.8 5 1 2 8 8 8 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORX95614.1 - 1.2e-07 31.9 1.0 0.058 14.2 0.3 6.9 5 2 4 9 9 8 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX95614.1 - 9.1e-06 24.8 3.7 0.013 14.3 0.0 4.5 3 1 2 5 5 5 2 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 ORX95614.1 - 5.5e-05 23.6 0.0 9.3 6.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX95614.1 - 0.00016 21.5 1.8 33 4.8 0.2 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Phage_ABA_S PF18066.1 ORX95614.1 - 0.0064 17.1 0.4 16 6.3 0.0 4.3 4 1 1 5 5 5 0 Phage ABA sandwich domain HTH_21 PF13276.6 ORX95614.1 - 0.035 14.2 0.0 21 5.4 0.0 3.1 2 0 0 2 2 2 0 HTH-like domain Hepatitis_core PF00906.20 ORX95614.1 - 0.051 13.1 0.0 8.4 5.9 0.0 2.2 1 1 1 2 2 2 0 Hepatitis core antigen Clathrin PF00637.20 ORX95614.1 - 0.071 13.0 0.2 91 2.9 0.1 4.5 5 0 0 5 5 5 0 Region in Clathrin and VPS TPR_2 PF07719.17 ORX95614.1 - 9.9 6.6 8.7 45 4.5 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX95614.1 - 10 6.7 6.0 56 4.3 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Acyltransferase PF01553.21 ORX95616.1 - 7.9e-08 32.0 0.0 2e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase DUF2470 PF10615.9 ORX95617.1 - 1.9e-13 50.9 0.0 2.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 ORX95617.1 - 2.7e-13 50.0 3.4 4.3e-13 49.4 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) AMH_N PF04709.12 ORX95617.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region EI24 PF07264.11 ORX95618.1 - 1.5e-13 51.3 4.6 2e-13 51.0 4.6 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) p47_phox_C PF08944.11 ORX95618.1 - 0.45 10.0 3.1 0.73 9.3 3.1 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Peptidase_S8 PF00082.22 ORX95620.1 - 2.5e-34 118.9 7.0 5.4e-34 117.8 7.0 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX95620.1 - 0.14 12.8 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 zf-rbx1 PF12678.7 ORX95621.1 - 2.7e-25 88.4 13.1 3.8e-25 87.9 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX95621.1 - 1.9e-17 63.1 9.9 2.5e-17 62.7 9.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ORX95621.1 - 2e-06 28.0 14.5 7.6e-05 23.0 14.5 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX95621.1 - 8.9e-05 22.2 3.5 8.9e-05 22.2 3.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX95621.1 - 0.0013 18.6 11.9 0.024 14.5 11.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX95621.1 - 0.12 12.3 10.9 0.39 10.6 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX95621.1 - 0.34 10.7 16.0 29 4.5 16.0 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 ORX95621.1 - 0.39 10.8 7.7 1.5 8.9 7.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 ORX95621.1 - 0.47 10.7 9.4 2.7 8.2 9.6 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORX95621.1 - 0.57 9.8 14.9 88 2.8 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type ATP-synt_ab PF00006.25 ORX95622.1 - 7.9e-62 208.7 0.0 1.1e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX95622.1 - 7.7e-22 77.6 1.7 1.8e-21 76.4 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ORX95622.1 - 0.015 14.7 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ORX95622.1 - 0.019 14.2 0.6 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 ORX95622.1 - 0.043 14.2 0.6 0.45 10.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORX95622.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORX95622.1 - 0.065 13.1 0.2 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 ORX95622.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 ORX95622.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Actin PF00022.19 ORX95623.1 - 1e-60 205.5 0.0 6.8e-58 196.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORX95623.1 - 5.6e-13 48.4 0.0 1.5e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 ORX95623.1 - 3.2e-05 24.3 0.0 5.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Cell division protein FtsA Ribosomal_L18 PF17135.4 ORX95624.1 - 2.5e-97 323.7 3.4 2.8e-97 323.6 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORX95624.1 - 0.0079 16.9 0.1 0.029 15.0 0.1 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SHNi-TPR PF10516.9 ORX95625.1 - 2.3e-13 49.4 0.0 6.2e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 ORX95625.1 - 1.7e-10 40.2 0.0 0.012 15.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX95625.1 - 6.7e-09 35.9 3.5 1.3e-06 28.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95625.1 - 2.1e-08 33.6 0.1 0.012 15.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX95625.1 - 0.00022 21.8 0.3 0.15 12.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORX95625.1 - 0.00047 19.8 3.2 3.1 7.5 0.0 4.4 4 1 1 5 5 5 2 TPR repeat FlxA PF14282.6 ORX95625.1 - 0.0034 17.3 9.2 0.01 15.8 9.2 1.8 1 0 0 1 1 1 1 FlxA-like protein TPR_6 PF13174.6 ORX95625.1 - 0.0094 16.5 0.0 0.59 10.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX95625.1 - 0.01 15.8 2.3 0.32 11.1 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 ORX95625.1 - 0.011 15.8 2.6 3 7.9 0.1 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 ORX95625.1 - 0.026 14.7 4.4 1.2 9.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF5082 PF16888.5 ORX95625.1 - 0.038 14.3 5.3 0.038 14.3 5.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) PhageMin_Tail PF10145.9 ORX95625.1 - 0.05 13.5 0.6 1.9 8.3 0.0 2.2 2 1 0 2 2 2 0 Phage-related minor tail protein SesA PF17107.5 ORX95625.1 - 0.067 13.4 1.7 0.15 12.2 1.7 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_14 PF13428.6 ORX95625.1 - 0.079 13.8 0.2 34 5.6 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1664 PF07889.12 ORX95625.1 - 0.14 12.2 4.6 0.25 11.4 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 ORX95625.1 - 0.17 11.6 8.3 1.4 8.6 8.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) MtrB PF05440.12 ORX95625.1 - 0.24 11.8 0.5 1.6 9.2 0.1 2.3 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Cauli_AT PF03233.13 ORX95625.1 - 0.25 11.3 5.7 0.67 9.9 5.2 2.0 1 1 1 2 2 2 0 Aphid transmission protein Corona_S2 PF01601.16 ORX95625.1 - 0.25 9.8 1.6 0.32 9.4 1.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DHR10 PF18595.1 ORX95625.1 - 4.1 7.5 12.3 2.3 8.3 9.6 2.0 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain Allexi_40kDa PF05549.11 ORX95625.1 - 4.1 6.8 7.3 3.5 7.1 4.9 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein ParB PF08775.10 ORX95625.1 - 4.4 7.8 8.6 1.1 9.7 3.6 2.2 1 1 1 2 2 2 0 ParB family TMPIT PF07851.13 ORX95625.1 - 5.9 6.0 6.2 8.9 5.5 6.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sod_Fe_C PF02777.18 ORX95626.1 - 3.5e-39 133.1 0.5 6.7e-39 132.2 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORX95626.1 - 4.5e-33 113.6 3.0 1.1e-32 112.4 3.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCV_T PF01571.21 ORX95627.1 - 2.1e-13 50.2 0.0 3.1e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Citrate_bind PF16114.5 ORX95628.1 - 1.1e-90 301.8 0.2 2.2e-90 300.9 0.2 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 ORX95628.1 - 2.2e-19 69.8 0.0 8.5e-17 61.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 ORX95628.1 - 2.4e-16 59.9 0.0 5.9e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 ORX95628.1 - 6.9e-14 52.3 0.0 2.1e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 ORX95628.1 - 2.2e-09 37.2 0.0 5.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ORX95628.1 - 2.1e-06 27.6 0.0 1.1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Pyr_redox_2 PF07992.14 ORX95629.1 - 3.8e-52 177.4 0.0 4.3e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX95629.1 - 2e-17 63.4 0.0 1.1e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX95629.1 - 7.8e-17 61.6 0.2 1.1e-14 54.7 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX95629.1 - 6.2e-05 22.3 0.2 0.00035 19.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ORX95629.1 - 0.0012 19.1 0.2 0.03 14.5 0.0 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX95629.1 - 0.0016 17.6 1.3 0.082 12.0 0.2 3.4 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORX95629.1 - 0.0025 17.3 0.1 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORX95629.1 - 0.007 15.5 1.0 0.32 10.0 0.2 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 ORX95629.1 - 0.03 13.6 0.5 0.13 11.5 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 ORX95629.1 - 0.031 14.7 0.4 0.53 10.8 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 ORX95629.1 - 0.052 12.2 0.7 0.31 9.7 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 ORX95629.1 - 0.077 12.6 0.2 9.5 5.7 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORX95629.1 - 0.11 11.3 0.1 0.32 9.8 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 ORX95629.1 - 0.17 11.0 0.4 7 5.7 0.0 2.7 2 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-CHY PF05495.12 ORX95630.1 - 1.7e-08 34.8 5.0 1.7e-08 34.8 5.0 3.4 3 0 0 3 3 3 1 CHY zinc finger zf-CCCH_4 PF18044.1 ORX95630.1 - 3.2e-05 23.6 1.8 3.2e-05 23.6 1.8 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 ORX95630.1 - 0.0019 18.0 1.3 0.0019 18.0 1.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AIG2_2 PF13772.6 ORX95631.1 - 0.0013 19.0 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 ORX95631.1 - 0.027 15.1 0.0 0.059 14.0 0.0 1.6 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like Glyco_hydro_10 PF00331.20 ORX95631.1 - 0.094 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Ribosomal_L34e PF01199.18 ORX95632.1 - 1.6e-46 156.5 4.0 2.2e-46 156.1 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.6 ORX95632.1 - 0.14 12.7 3.8 0.56 10.8 3.8 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Ribosomal_L10 PF00466.20 ORX95633.1 - 1.9e-22 79.3 0.8 4.6e-22 78.0 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORX95633.1 - 4e-22 78.0 0.1 6.9e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 ORX95633.1 - 1.1e-18 67.6 4.1 1.3e-18 67.3 2.3 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein VEG PF06257.11 ORX95633.1 - 0.066 13.3 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Biofilm formation stimulator VEG VirE_N PF08800.10 ORX95633.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 VirE N-terminal domain Cg6151-P PF10233.9 ORX95634.1 - 4.2e-20 72.1 18.0 5.1e-20 71.9 18.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF3693 PF12472.8 ORX95634.1 - 0.1 12.2 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Phage related protein EI24 PF07264.11 ORX95634.1 - 0.88 9.8 13.2 1.1 9.5 13.2 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2070 PF09843.9 ORX95634.1 - 1.7 6.8 15.2 2 6.6 15.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) S_4TM PF18159.1 ORX95634.1 - 5.5 6.2 12.7 0.042 13.2 1.0 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Rod_C PF10493.9 ORX95635.1 - 1.1e-72 245.2 10.8 2.4e-72 244.1 10.8 1.5 1 0 0 1 1 1 1 Rough deal protein C-terminal region MRP-S22 PF10245.9 ORX95635.1 - 2.4e-05 24.2 0.2 5.5e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 RNA_pol_Rpc34 PF05158.12 ORX95636.1 - 1.9e-92 310.2 0.3 2.8e-92 309.7 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 ORX95636.1 - 0.0018 18.4 0.7 0.084 13.0 0.2 2.7 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC Penicillinase_R PF03965.16 ORX95636.1 - 0.026 14.9 0.8 0.79 10.1 0.0 2.6 1 1 1 2 2 2 0 Penicillinase repressor HxlR PF01638.17 ORX95636.1 - 0.029 14.2 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix MarR PF01047.22 ORX95636.1 - 0.053 13.5 0.4 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 MarR family RPA_C PF08784.11 ORX95636.1 - 0.06 14.0 0.5 6.6 7.4 0.1 2.7 3 0 0 3 3 3 0 Replication protein A C terminal bZIP_2 PF07716.15 ORX95637.1 - 4.9e-09 36.1 7.5 4.9e-09 36.1 7.5 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX95637.1 - 1.7e-06 28.1 12.1 1.7e-06 28.1 12.1 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX95637.1 - 0.0084 16.6 8.8 0.015 15.8 8.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1465 PF07323.12 ORX95637.1 - 0.12 12.2 7.9 0.19 11.5 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Shugoshin_N PF07558.11 ORX95637.1 - 0.17 11.8 9.6 0.74 9.7 3.6 2.9 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region CpxA_peri PF16527.5 ORX95637.1 - 0.59 10.5 2.4 0.95 9.8 2.4 1.3 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain Ank_5 PF13857.6 ORX95638.1 - 4.7e-07 30.0 0.1 0.0035 17.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORX95638.1 - 9.5e-07 29.3 0.8 0.016 15.8 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX95638.1 - 1.2e-06 29.0 1.1 0.0041 17.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Spc7 PF08317.11 ORX95638.1 - 4.5e-05 22.5 5.1 4.5e-05 22.5 5.1 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Ank_3 PF13606.6 ORX95638.1 - 0.00085 19.6 0.8 0.078 13.6 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 ORX95638.1 - 0.0014 18.5 0.1 0.018 14.9 0.1 2.6 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.30 ORX95638.1 - 0.024 15.1 0.7 2.2 8.8 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat HAUS-augmin3 PF14932.6 ORX95638.1 - 0.076 12.6 6.5 0.36 10.4 6.4 2.2 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3958 PF13125.6 ORX95638.1 - 0.14 12.4 7.0 0.23 11.7 5.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) Prominin PF05478.11 ORX95638.1 - 0.46 8.4 5.8 0.72 7.7 5.8 1.2 1 0 0 1 1 1 0 Prominin FUSC PF04632.12 ORX95638.1 - 5.5 5.4 4.9 8 4.9 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 ORX95638.1 - 7.5 6.6 8.1 2.8 8.0 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ras PF00071.22 ORX95639.1 - 2.1e-57 193.2 0.0 2.5e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95639.1 - 1.3e-33 115.8 0.0 1.8e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95639.1 - 9.9e-16 57.7 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX95639.1 - 1.1e-06 28.3 0.0 6.6e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORX95639.1 - 3.1e-05 23.5 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORX95639.1 - 9.3e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX95639.1 - 0.0004 19.8 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORX95639.1 - 0.011 15.7 0.1 6.6 6.6 0.0 2.5 1 1 2 3 3 3 0 RsgA GTPase ATPase PF06745.13 ORX95639.1 - 0.027 13.8 0.1 0.05 12.9 0.0 1.5 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 ORX95639.1 - 0.081 13.2 0.1 0.39 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 ORX95639.1 - 0.093 11.9 0.0 3.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 ORX95639.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 ORX95639.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 ORX95639.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 ORX95639.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin LIM PF00412.22 ORX95640.1 - 1.4e-20 73.3 34.3 2.8e-09 37.1 3.9 4.1 5 0 0 5 5 5 3 LIM domain DUF2724 PF10893.8 ORX95640.1 - 0.084 12.7 0.1 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) EF-hand_1 PF00036.32 ORX95641.1 - 2.9e-22 76.5 4.2 3.6e-06 26.1 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 ORX95641.1 - 3.8e-21 75.3 1.3 5.7e-14 52.3 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX95641.1 - 6.1e-18 63.2 1.8 0.00017 21.2 0.0 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 ORX95641.1 - 1.3e-16 59.2 0.4 0.00011 21.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 ORX95641.1 - 2.6e-13 49.6 4.8 0.00058 19.7 0.2 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 ORX95641.1 - 8.9e-07 28.8 2.7 0.13 12.2 0.0 3.4 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORX95641.1 - 0.00037 20.8 0.1 0.13 12.6 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORX95641.1 - 0.0083 16.4 0.5 6.4 7.2 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain S10_plectin PF03501.15 ORX95641.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain Pan3_PK PF18101.1 ORX95641.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain KH_1 PF00013.29 ORX95642.1 - 3.9e-41 138.7 12.8 4.5e-17 61.6 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX95642.1 - 2.6e-09 36.8 11.5 0.016 15.0 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX95642.1 - 7.6e-08 32.1 3.9 0.12 12.2 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORX95642.1 - 0.00025 21.1 5.9 0.071 13.2 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain DUF2040 PF09745.9 ORX95643.1 - 2.1e-39 134.3 18.9 2.1e-39 134.3 18.9 3.4 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Acetyltransf_3 PF13302.7 ORX95644.1 - 7.8e-16 59.0 0.0 1.5e-15 58.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX95644.1 - 3.8e-05 23.9 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-C2H2 PF00096.26 ORX95646.1 - 2.2e-11 43.6 19.3 1.8e-06 28.1 1.8 3.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95646.1 - 2.2e-06 28.0 14.3 0.00028 21.5 1.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95646.1 - 9.5e-06 25.8 4.2 0.00013 22.2 0.8 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORX95646.1 - 1.4e-05 25.3 1.8 1.4e-05 25.3 1.8 3.9 5 0 0 5 5 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX95646.1 - 0.00068 19.6 0.5 0.00068 19.6 0.5 2.7 3 0 0 3 3 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORX95646.1 - 0.00084 19.9 10.1 0.0056 17.3 0.3 3.1 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-met PF12874.7 ORX95646.1 - 0.0011 19.2 0.2 0.085 13.3 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORX95646.1 - 0.0024 18.1 2.8 0.0039 17.5 2.8 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf_ZIC PF18366.1 ORX95646.1 - 0.0047 17.0 0.2 0.0047 17.0 0.2 3.4 2 2 1 3 3 3 1 Zic proteins zinc finger domain Zap1_zf2 PF18217.1 ORX95646.1 - 0.076 13.0 5.0 0.18 11.8 0.0 2.8 3 0 0 3 3 3 0 Zap1 zinc finger 2 zf-LYAR PF08790.11 ORX95646.1 - 0.27 11.2 0.4 0.27 11.2 0.4 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 ORX95646.1 - 0.84 9.3 6.7 13 5.6 0.0 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Peptidase_M41 PF01434.18 ORX95647.1 - 1.2e-66 224.2 0.1 2e-66 223.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORX95647.1 - 8.1e-43 146.0 0.0 1.7e-42 145.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX95647.1 - 3.1e-15 55.7 0.4 6.5e-15 54.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ORX95647.1 - 2.1e-10 40.9 0.1 5.2e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 ORX95647.1 - 0.002 18.5 0.1 0.028 14.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX95647.1 - 0.0054 17.0 0.1 0.45 10.8 0.1 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 ORX95647.1 - 0.0067 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 ORX95647.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX95647.1 - 0.034 14.3 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORX95647.1 - 0.037 14.0 0.5 0.13 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ORX95647.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SPATIAL PF15256.6 ORX95647.1 - 0.087 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 SPATIAL AAA_17 PF13207.6 ORX95647.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORX95647.1 - 0.17 11.2 0.1 0.43 9.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI COX6B PF02297.17 ORX95648.1 - 1.8e-20 72.9 5.3 2.2e-20 72.6 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 ORX95648.1 - 0.0056 16.7 1.6 0.0092 16.0 1.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 ORX95648.1 - 0.018 15.0 0.4 0.029 14.3 0.4 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain YozE_SAM_like PF06855.12 ORX95648.1 - 0.077 13.2 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 YozE SAM-like fold cNMP_binding PF00027.29 ORX95649.1 - 6.3e-42 141.6 0.2 2.8e-20 72.2 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ORX95649.1 - 1.2e-07 31.3 0.0 2.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit G_glu_transpept PF01019.21 ORX95649.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase SpoIIIAH PF12685.7 ORX95649.1 - 0.02 14.7 0.9 0.02 14.7 0.9 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein GPI-anchored PF10342.9 ORX95650.1 - 1.8e-23 83.1 2.1 4.6e-12 46.5 0.1 2.3 2 0 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pur_ac_phosph_N PF16656.5 ORX95650.1 - 0.015 15.8 0.1 10 6.8 0.1 2.7 2 2 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Gti1_Pac2 PF09729.9 ORX95651.1 - 0.0065 16.6 0.4 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family PAS PF00989.25 ORX95652.1 - 1.9e-05 24.6 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX95652.1 - 3.8e-05 23.9 0.0 0.0045 17.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORX95652.1 - 6.7e-05 23.1 0.0 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX95652.1 - 0.00012 22.3 0.0 0.38 11.0 0.0 2.6 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 ORX95652.1 - 0.16 12.0 0.0 3.2 7.9 0.0 2.5 3 0 0 3 3 3 0 PAS domain GST_C_3 PF14497.6 ORX95653.1 - 4e-21 75.0 0.2 7.6e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX95653.1 - 6.8e-09 35.8 0.1 1.3e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX95653.1 - 2.6e-08 34.1 0.0 6.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX95653.1 - 0.0015 18.5 0.0 0.0037 17.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX95653.1 - 0.08 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORX95653.1 - 0.14 11.9 0.4 0.33 10.8 0.4 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 ORX95654.1 - 2e-44 152.0 0.0 5.8e-27 94.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95654.1 - 6.2e-24 84.7 0.0 3.9e-13 49.3 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase DivIC PF04977.15 ORX95654.1 - 0.0051 16.5 1.0 0.032 14.0 0.5 2.5 3 0 0 3 3 3 1 Septum formation initiator bZIP_2 PF07716.15 ORX95654.1 - 0.0051 16.9 1.5 0.012 15.7 1.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper CLZ PF16526.5 ORX95654.1 - 0.1 13.0 0.3 0.67 10.4 0.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vps54 PF07928.12 ORX95654.1 - 0.14 12.6 1.1 1.9 8.9 0.2 2.6 2 1 0 2 2 2 0 Vps54-like protein zf-H2C2_2 PF13465.6 ORX95655.1 - 3.6e-18 65.1 21.1 7.6e-06 26.1 2.0 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORX95655.1 - 1.1e-15 57.1 26.2 1.1e-06 28.8 0.3 4.2 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95655.1 - 9.6e-08 32.2 26.7 0.0069 17.1 0.3 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX95655.1 - 1.1e-05 25.7 6.6 0.0075 16.5 0.2 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon CHORD PF04968.12 ORX95655.1 - 0.00094 19.9 4.2 0.00094 19.9 4.2 2.7 2 1 0 2 2 2 1 CHORD FOXP-CC PF16159.5 ORX95655.1 - 0.0054 17.3 9.1 0.26 11.9 0.2 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX95655.1 - 0.025 15.2 10.7 0.41 11.4 3.0 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger BolA PF01722.18 ORX95655.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.7 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_4 PF13894.6 ORX95671.1 - 1.2e-06 28.8 17.4 3.8e-05 24.2 0.9 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX95671.1 - 2.8e-06 27.5 18.0 7.6e-06 26.1 1.7 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORX95671.1 - 3.2e-05 23.8 4.1 8e-05 22.5 0.5 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX95671.1 - 8.9e-05 22.7 2.3 8.9e-05 22.7 2.3 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX95671.1 - 0.00047 20.4 2.3 0.00061 20.0 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX95671.1 - 0.0013 19.3 8.6 0.012 16.2 0.3 2.8 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX95671.1 - 0.015 16.0 6.1 0.076 13.7 4.2 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf_ZIC PF18366.1 ORX95671.1 - 0.02 15.0 0.1 0.02 15.0 0.1 3.6 4 1 0 4 4 4 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 ORX95671.1 - 0.11 12.8 10.1 3 8.2 4.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 ORX95671.1 - 0.15 12.3 7.5 0.075 13.3 5.2 1.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-BED PF02892.15 ORX95671.1 - 0.7 10.0 0.1 0.7 10.0 0.1 3.4 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 ORX95671.1 - 1 9.7 10.3 76 3.7 9.9 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) HNH_5 PF14279.6 ORX95671.1 - 4.8 7.1 8.8 7.4 6.5 0.3 3.1 2 1 1 3 3 3 0 HNH endonuclease DDHD PF02862.17 ORX95672.1 - 4.6e-31 108.7 0.1 7e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 ORX95672.1 - 0.0021 17.6 0.0 0.007 15.9 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Glyco_trans_1_2 PF13524.6 ORX95672.1 - 0.086 13.2 0.0 6.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 CRAL_TRIO PF00650.20 ORX95673.1 - 1.2e-19 70.5 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORX95673.1 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3884 PF13024.6 ORX95673.1 - 0.16 11.5 1.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3884) Ras PF00071.22 ORX95674.1 - 1.6e-52 177.4 0.0 1.9e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95674.1 - 8.2e-21 74.4 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95674.1 - 4.9e-10 39.1 0.0 5.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX95674.1 - 1.1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORX95674.1 - 0.0039 16.6 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORX95674.1 - 0.0041 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 ORX95674.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 ORX95674.1 - 0.018 15.5 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORX95674.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ETF_QO PF05187.13 ORX95674.1 - 0.074 13.2 0.3 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S TniB PF05621.11 ORX95674.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 ORX95674.1 - 0.15 12.0 0.0 16 5.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Cation_efflux PF01545.21 ORX95675.1 - 6.5e-55 186.0 9.4 9.2e-55 185.5 9.4 1.2 1 0 0 1 1 1 1 Cation efflux family VanZ PF04892.12 ORX95675.1 - 0.18 12.4 3.5 0.32 11.7 1.6 2.3 2 1 0 2 2 2 0 VanZ like family RGS PF00615.19 ORX95676.1 - 7.7e-16 58.4 0.8 1.8e-15 57.2 0.8 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain FYVE PF01363.21 ORX95677.1 - 3.7e-14 52.6 3.1 3.7e-14 52.6 3.1 3.0 2 1 1 3 3 3 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 ORX95677.1 - 5.2e-13 48.6 14.3 5.2e-13 48.6 14.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.9 ORX95677.1 - 1.2e-06 28.6 0.2 0.014 15.3 0.1 2.5 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding zf-RING_2 PF13639.6 ORX95677.1 - 0.0018 18.5 15.0 0.0018 18.5 15.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX95677.1 - 0.0049 16.7 16.1 0.0049 16.7 16.1 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX95677.1 - 0.01 15.7 13.2 0.01 15.7 13.2 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORX95677.1 - 0.011 15.6 33.3 0.033 14.1 15.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain FYVE_2 PF02318.16 ORX95677.1 - 2.6 8.3 21.7 0.054 13.7 4.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Pyr_redox_2 PF07992.14 ORX95679.1 - 6.4e-55 186.5 0.0 7.4e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX95679.1 - 1.6e-19 70.3 0.0 6.1e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX95679.1 - 9.8e-18 64.5 0.3 3.1e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORX95679.1 - 2.5e-06 26.9 0.3 0.0013 17.9 0.4 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORX95679.1 - 3.5e-06 26.6 0.1 7.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORX95679.1 - 2.2e-05 23.9 0.2 6.2e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORX95679.1 - 0.00057 18.7 0.3 0.016 14.0 0.6 2.6 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.24 ORX95679.1 - 0.00086 18.5 2.1 0.014 14.5 0.7 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 ORX95679.1 - 0.0018 18.5 0.3 0.0059 16.8 0.1 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain EF-hand_11 PF08976.11 ORX95679.1 - 0.0077 17.1 0.0 0.018 15.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain DAO PF01266.24 ORX95679.1 - 0.036 13.7 0.4 0.68 9.4 1.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX95679.1 - 0.087 12.1 0.5 0.24 10.6 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORX95679.1 - 0.089 13.2 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 ORX95679.1 - 0.17 10.7 0.1 0.41 9.5 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 ORX95679.1 - 0.18 11.0 0.4 0.29 10.3 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 ORX95679.1 - 0.18 10.9 0.0 0.84 8.7 0.0 2.1 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Rhodanese PF00581.20 ORX95680.1 - 1e-13 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF2671 PF10877.8 ORX95680.1 - 0.097 12.5 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) Ran-binding PF05508.11 ORX95681.1 - 0.19 10.7 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Sigma70_ner PF04546.13 ORX95681.1 - 2 8.3 5.3 2 8.3 0.1 2.2 2 1 0 2 2 2 0 Sigma-70, non-essential region PPR_2 PF13041.6 ORX95682.1 - 9.5e-64 211.4 18.0 6.2e-16 58.3 0.0 11.8 3 1 10 13 13 13 11 PPR repeat family PPR PF01535.20 ORX95682.1 - 3.1e-56 183.8 15.4 3.7e-08 33.1 0.2 11.6 12 0 0 12 12 12 10 PPR repeat PPR_3 PF13812.6 ORX95682.1 - 4.7e-46 154.7 15.9 1.1e-12 47.9 0.0 6.8 3 1 6 9 9 8 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX95682.1 - 1e-38 130.7 6.6 4.6e-09 35.8 0.0 10.5 11 1 0 11 11 11 7 PPR repeat PPR_long PF17177.4 ORX95682.1 - 3.6e-28 98.4 2.4 3.6e-11 42.8 0.1 4.4 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX95682.1 - 8.3e-07 29.4 4.7 0.11 12.9 0.3 5.9 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORX95682.1 - 7.4e-06 26.4 0.0 1.9 9.5 0.0 5.7 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORX95682.1 - 6e-05 23.5 0.0 0.061 13.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 ORX95682.1 - 0.0002 21.2 2.7 3.9 7.3 0.0 4.8 3 2 2 5 5 5 2 Region in Clathrin and VPS MRP-S27 PF10037.9 ORX95682.1 - 0.0018 17.2 0.4 1.1 8.0 0.0 2.8 2 1 1 3 3 3 2 Mitochondrial 28S ribosomal protein S27 TPR_7 PF13176.6 ORX95682.1 - 0.01 15.8 0.0 11 6.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat BKACE PF05853.12 ORX95682.1 - 0.012 15.0 0.1 1.7 7.9 0.0 2.7 1 1 0 2 2 2 0 beta-keto acid cleavage enzyme MNE1 PF13762.6 ORX95682.1 - 0.014 15.4 0.4 0.75 9.8 0.0 3.1 3 1 0 3 3 3 0 Mitochondrial splicing apparatus component B12-binding_2 PF02607.17 ORX95682.1 - 0.02 15.3 0.0 9.1 6.8 0.0 3.9 4 0 0 4 4 4 0 B12 binding domain DUF1955 PF09205.10 ORX95682.1 - 0.056 13.2 0.0 1 9.1 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1955) ECSIT PF06239.11 ORX95682.1 - 0.071 12.2 5.4 18 4.3 0.0 4.8 2 2 3 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway DSBA PF01323.20 ORX95682.1 - 0.13 12.1 0.0 7 6.4 0.0 2.9 2 1 1 3 3 3 0 DSBA-like thioredoxin domain TPR_1 PF00515.28 ORX95682.1 - 0.13 12.1 1.9 4.3 7.3 0.0 4.1 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX95682.1 - 0.15 12.2 0.3 74 3.8 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Ion_trans_2 PF07885.16 ORX95683.1 - 2.7e-27 94.5 28.9 1.7e-16 59.9 10.8 3.7 4 1 0 4 4 4 2 Ion channel FAM184 PF15665.5 ORX95683.1 - 0.83 9.4 3.6 0.43 10.3 0.2 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B IRK PF01007.20 ORX95683.1 - 2.4 8.0 15.5 0.56 10.0 0.7 3.1 2 1 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain Terpene_synth_C PF03936.16 ORX95684.1 - 1.8e-07 30.8 7.8 2.4e-06 27.1 7.8 2.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 ORX95684.1 - 0.00016 20.7 1.2 0.0002 20.4 0.1 1.7 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) LANC_like PF05147.13 ORX95684.1 - 0.013 14.1 0.1 0.023 13.3 0.1 1.3 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DUF507 PF04368.13 ORX95684.1 - 0.077 12.9 1.6 0.46 10.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF507) Mrpl_C PF18502.1 ORX95684.1 - 0.96 9.8 7.0 1.1 9.6 0.1 3.3 3 1 1 4 4 4 0 54S ribosomal protein L8 C-terminal domain E1_dh PF00676.20 ORX95685.1 - 5.1e-120 400.0 0.0 5.9e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORX95685.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 ORX95685.1 - 0.028 15.4 1.8 3.4 8.7 0.1 3.0 2 1 0 2 2 2 0 KRTAP type 7 family INSIG PF07281.12 ORX95686.1 - 1.3e-27 96.9 11.0 4.1e-26 91.9 11.0 2.4 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) TssN PF17555.2 ORX95686.1 - 0.0062 16.0 1.2 0.0062 16.0 1.2 1.7 2 0 0 2 2 2 1 Type VI secretion system, TssN YtpI PF14007.6 ORX95686.1 - 0.15 12.2 5.7 8.9 6.5 0.0 2.7 2 1 0 2 2 2 0 YtpI-like protein DUF2198 PF09964.9 ORX95686.1 - 1.1 9.4 6.9 0.17 12.0 2.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF2070 PF09843.9 ORX95686.1 - 8.5 4.5 10.2 10 4.3 10.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungal_trans PF04082.18 ORX95687.1 - 6.3e-35 120.5 1.2 1.2e-34 119.6 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1834 PF08873.11 ORX95687.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) Myticin-prepro PF10690.9 ORX95714.1 - 0.0022 18.2 0.3 0.0033 17.6 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel DUF4597 PF15366.6 ORX95715.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Toxin_TOLIP PF00087.21 ORX95718.1 - 0.58 10.5 7.5 1.9 8.8 0.7 2.5 2 0 0 2 2 2 0 Snake toxin and toxin-like protein Chlam_OMP3 PF03503.13 ORX95718.1 - 0.76 10.1 5.7 0.11 12.8 1.4 1.8 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 SidC_N PF18219.1 ORX95723.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 SidC N-terminal domain DUF562 PF04763.12 ORX95724.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF562) Mrx7 PF10906.8 ORX95733.1 - 0.015 15.5 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 MIOREX complex component 7 Glyoxalase_5 PF14696.6 ORX95733.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Syntaxin_2 PF14523.6 ORX95734.1 - 9.7e-19 67.6 10.3 2.8e-18 66.2 3.9 2.2 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 ORX95734.1 - 2.6e-06 27.3 0.9 5.1e-06 26.4 0.3 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 ORX95734.1 - 3.9e-06 26.7 10.8 1e-05 25.3 10.8 1.7 1 1 0 1 1 1 1 Syntaxin SlyX PF04102.12 ORX95734.1 - 0.15 12.7 3.6 0.27 11.9 0.3 2.7 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.12 ORX95734.1 - 2.6 8.1 8.6 3.9 7.5 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.32 ORX95735.1 - 1.1e-11 45.1 9.8 0.021 15.7 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX95735.1 - 2.5e-05 24.5 0.2 0.93 9.8 0.0 4.2 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX95735.1 - 0.00026 20.4 1.2 0.035 13.4 0.1 2.9 2 1 1 3 3 3 2 WD40-like domain Nucleoporin_N PF08801.11 ORX95735.1 - 0.00049 19.0 0.1 0.018 13.8 0.1 2.2 1 1 1 2 2 2 1 Nup133 N terminal like eIF2A PF08662.11 ORX95735.1 - 0.0055 16.6 0.7 0.14 12.0 0.2 3.0 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A SCAB-PH PF17684.1 ORX95735.1 - 0.034 14.4 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 PH domain of plant-specific actin-binding protein EF-hand_7 PF13499.6 ORX95736.1 - 2.7e-11 43.7 1.5 3.1e-11 43.6 0.4 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 ORX95736.1 - 1.4e-10 39.9 2.5 4.6e-06 25.8 0.6 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 ORX95736.1 - 2.8e-10 39.2 1.9 0.00057 19.3 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORX95736.1 - 1.7e-09 36.9 2.1 4.2e-06 26.2 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORX95736.1 - 2.6e-06 27.2 2.7 0.0057 16.5 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX95736.1 - 0.036 14.4 0.0 0.64 10.4 0.0 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Uteroglobin PF01099.17 ORX95737.1 - 0.35 11.2 3.5 0.27 11.6 1.2 1.9 1 1 1 2 2 2 0 Uteroglobin family DUF3245 PF11595.8 ORX95737.1 - 1 9.8 12.5 0.058 13.9 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) NuA4 PF09340.10 ORX95737.1 - 7.1 6.6 10.3 18 5.3 7.3 2.7 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DNA_primase_S PF01896.19 ORX95738.1 - 2.3e-59 200.4 0.1 3.9e-59 199.7 0.1 1.4 1 0 0 1 1 1 1 DNA primase small subunit Stealth_CR4 PF17103.5 ORX95738.1 - 0.11 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 DUF1168 PF06658.12 ORX95739.1 - 3.2e-40 137.1 15.6 4.7e-40 136.5 15.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Borrelia_P83 PF05262.11 ORX95739.1 - 4.3 5.7 17.9 4.4 5.7 17.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.10 ORX95739.1 - 5 7.2 11.4 9 6.3 11.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CHAP PF05257.16 ORX95740.1 - 2.2e-10 40.9 1.6 2.2e-10 40.9 1.6 2.2 2 0 0 2 2 2 1 CHAP domain TMEM43 PF07787.12 ORX95740.1 - 0.13 11.7 5.2 0.23 10.8 5.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 Polysacc_lyase PF14099.6 ORX95741.1 - 5.9e-05 23.0 0.1 7.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.11 ORX95741.1 - 0.0069 16.5 0.0 0.0093 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Myb_DNA-binding PF00249.31 ORX95742.1 - 1.2e-30 105.5 6.1 1.5e-11 44.3 0.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX95742.1 - 5.9e-20 71.3 3.5 1.5e-08 34.7 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 ORX95742.1 - 1.3e-06 28.4 0.0 0.0081 16.2 0.0 2.8 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 ORX95742.1 - 0.00088 19.3 4.8 9.2 6.4 0.0 3.1 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 ORX95742.1 - 0.00092 19.1 0.6 0.0084 16.0 0.0 2.4 2 1 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 ORX95742.1 - 0.016 15.5 1.1 0.016 15.5 1.1 2.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 ORX95742.1 - 0.095 13.1 4.0 0.14 12.6 1.9 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain CHAP PF05257.16 ORX95743.1 - 1.6e-11 44.6 0.9 1.6e-11 44.6 0.9 2.3 2 1 0 2 2 2 1 CHAP domain Presenilin PF01080.17 ORX95743.1 - 2.5 6.8 4.0 2.9 6.6 4.0 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 ORX95743.1 - 3.2 6.2 6.6 3.6 6.0 6.6 1.1 1 0 0 1 1 1 0 Macoilin family Spt20 PF12090.8 ORX95743.1 - 4 7.0 14.9 5.6 6.5 14.9 1.1 1 0 0 1 1 1 0 Spt20 family FHA PF00498.26 ORX95744.1 - 7.2e-16 58.3 0.0 1.5e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORX95744.1 - 3.5e-11 42.6 7.5 3.5e-11 42.6 7.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 ORX95744.1 - 2.3e-09 37.5 7.6 4.1e-09 36.6 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX95744.1 - 7e-06 25.8 7.6 1.5e-05 24.8 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX95744.1 - 6.1e-05 23.2 7.6 0.00013 22.2 7.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORX95744.1 - 0.00043 20.1 9.3 0.0011 18.8 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORX95744.1 - 0.0046 17.0 4.4 0.0084 16.1 4.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Yop-YscD_cpl PF16697.5 ORX95744.1 - 0.0063 16.8 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 ORX95744.1 - 0.035 14.0 4.7 0.079 12.9 4.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 ORX95744.1 - 0.063 13.3 11.0 0.12 12.3 11.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORX95744.1 - 0.46 10.2 8.9 1 9.1 5.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 ORX95744.1 - 0.87 9.7 10.0 2 8.5 10.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger IlvN PF07991.12 ORX95745.1 - 1.5e-43 148.2 0.0 2.5e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORX95745.1 - 1.1e-42 145.7 0.1 2.4e-42 144.6 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 ORX95745.1 - 0.0014 18.9 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ORX95745.1 - 0.055 13.5 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Iso_dh PF00180.20 ORX95746.1 - 6.4e-125 416.9 0.0 7.4e-125 416.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TbpB_C PF17483.2 ORX95747.1 - 0.094 13.1 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B FTHFS PF01268.19 ORX95748.1 - 1e-264 878.9 0.0 1.6e-264 878.3 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 ORX95748.1 - 9.5e-67 223.3 0.4 9.5e-67 223.3 0.4 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ORX95748.1 - 2.9e-40 137.2 0.6 1.1e-39 135.3 0.6 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 ORX95748.1 - 0.021 13.7 0.1 0.042 12.8 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family KH_1 PF00013.29 ORX95749.1 - 0.00019 21.2 0.1 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 KH domain Sec20 PF03908.13 ORX95749.1 - 0.017 15.0 4.7 0.24 11.3 1.6 3.3 3 0 0 3 3 3 0 Sec20 Mif2_N PF15624.6 ORX95749.1 - 0.23 12.2 5.7 1.2 9.9 0.3 2.3 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RGS PF00615.19 ORX95750.1 - 9.7e-15 54.9 0.3 9.3e-11 42.0 0.2 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PAP1 PF08601.10 ORX95750.1 - 0.022 14.5 0.8 0.027 14.2 0.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 7TM_GPCR_Srz PF10325.9 ORX95750.1 - 0.049 13.0 5.3 0.072 12.4 5.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz UQ_con PF00179.26 ORX95751.1 - 1.9e-49 166.9 0.0 2.1e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORX95751.1 - 0.0018 18.6 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 ORX95751.1 - 0.0058 16.5 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 ORX95751.1 - 0.0072 16.0 0.0 0.0085 15.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B IF-2B PF01008.17 ORX95753.1 - 2.1e-76 256.8 0.1 2.6e-76 256.5 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PS_pyruv_trans PF04230.13 ORX95753.1 - 0.047 13.6 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase HLH PF00010.26 ORX95754.1 - 3.7e-19 68.4 2.0 6.1e-19 67.7 2.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LCE6A PF15858.5 ORX95754.1 - 0.16 12.8 0.1 0.16 12.8 0.1 2.5 1 1 1 2 2 2 0 Late cornified envelope protein 6A family Complex1_LYR PF05347.15 ORX95755.1 - 4.9e-08 32.9 0.4 5.7e-08 32.7 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORX95755.1 - 0.00036 21.2 0.1 0.00049 20.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORX95755.1 - 0.0046 17.5 0.2 0.0058 17.2 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF1896 PF08989.10 ORX95755.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) SQS_PSY PF00494.19 ORX95756.1 - 1e-41 143.2 0.0 1.3e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Arrestin_C PF02752.22 ORX95757.1 - 8.7e-13 48.9 2.0 5.4e-12 46.3 0.8 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX95757.1 - 1.4e-12 47.9 0.1 6.9e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX95757.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Ppnp PF06865.11 ORX95757.1 - 0.14 12.6 0.0 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyrimidine/purine nucleoside phosphorylase Cohesin_HEAT PF12765.7 ORX95758.1 - 0.059 13.7 0.0 0.79 10.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion LCIB_C_CA PF18599.1 ORX95758.1 - 0.45 9.8 7.3 7.7 5.7 0.1 5.1 3 0 0 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases ECH_1 PF00378.20 ORX95759.1 - 1.4e-20 73.7 0.0 1.7e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX95759.1 - 8.2e-12 45.3 0.0 1.1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AGOG PF09171.10 ORX95759.1 - 0.086 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Pkinase PF00069.25 ORX95760.1 - 2.9e-69 233.4 0.0 3.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95760.1 - 7.8e-36 123.7 0.0 9.9e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX95760.1 - 0.0055 15.7 0.2 0.0078 15.2 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain P16-Arc PF04699.14 ORX95761.1 - 0.027 15.0 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2405 PF10293.9 ORX95762.1 - 0.069 13.1 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) EBP PF05241.12 ORX95763.1 - 1.9e-48 164.3 2.5 2.2e-48 164.1 2.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein LIM_bind PF01803.16 ORX95764.1 - 5.1e-45 153.9 1.0 5.1e-45 153.9 1.0 4.0 2 2 0 2 2 2 1 LIM-domain binding protein GATA PF00320.27 ORX95765.1 - 5.9e-15 54.6 5.9 5.9e-15 54.6 5.9 2.5 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.12 ORX95765.1 - 1.4e-12 47.7 0.1 2.3e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 ORX95765.1 - 1.1e-07 31.9 1.0 5.4e-07 29.7 0.1 2.4 3 0 0 3 3 3 1 PAS domain PAS_9 PF13426.7 ORX95765.1 - 2.5e-07 30.9 0.1 9.5e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ORX95765.1 - 5.2e-07 29.7 0.1 1.7e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.10 ORX95765.1 - 0.034 14.3 0.5 0.084 13.0 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Peptidase_Prp PF04327.12 ORX95765.1 - 0.1 12.9 0.1 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Cysteine protease Prp DZR PF12773.7 ORX95765.1 - 0.13 12.3 1.5 0.7 10.0 1.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon Toxin_YhaV PF11663.8 ORX95765.1 - 0.2 11.7 2.1 0.33 11.0 1.0 1.9 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system SIR2 PF02146.17 ORX95766.1 - 4.1e-57 192.9 0.0 6.1e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Ribosomal_S7e PF01251.18 ORX95767.1 - 3.8e-85 284.3 2.7 4.3e-85 284.1 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rhodanese PF00581.20 ORX95769.1 - 7.5e-14 52.2 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain PPR_2 PF13041.6 ORX95770.1 - 1.6e-67 223.5 29.3 5.2e-16 58.6 0.4 11.3 6 3 6 12 12 12 10 PPR repeat family PPR_3 PF13812.6 ORX95770.1 - 2.3e-52 174.9 7.7 3.8e-12 46.1 0.0 9.2 7 2 2 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX95770.1 - 1.4e-49 168.4 2.9 5.3e-15 55.3 0.0 5.1 1 1 5 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORX95770.1 - 4.3e-46 152.0 24.8 2e-07 30.8 0.4 14.5 16 0 0 16 16 16 7 PPR repeat PPR_1 PF12854.7 ORX95770.1 - 9e-41 137.3 9.2 4.7e-09 35.8 0.0 10.5 11 0 0 11 11 11 7 PPR repeat RPM2 PF08579.11 ORX95770.1 - 1.9e-06 28.3 8.8 1.1 9.7 0.1 6.9 1 1 6 8 8 8 3 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ORX95770.1 - 3.4e-06 26.9 0.1 4.1 7.3 0.0 5.6 2 2 3 6 6 6 2 Mitochondrial ATPase expression TPR_14 PF13428.6 ORX95770.1 - 7.5e-06 26.3 0.0 8.4 7.5 0.0 7.1 7 1 1 8 8 7 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX95770.1 - 0.00024 20.1 2.6 1.3 7.8 0.0 4.1 1 1 1 4 4 4 2 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.11 ORX95770.1 - 0.0004 19.6 0.5 5 6.2 0.0 3.7 3 1 0 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 ORX95770.1 - 0.0013 18.6 0.2 0.29 11.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 ORX95770.1 - 0.0014 18.4 3.2 1 9.1 0.0 5.0 4 1 1 6 6 6 1 26S proteasome subunit RPN7 Xpo1 PF08389.12 ORX95771.1 - 2.9e-05 24.2 0.0 2.9e-05 24.2 0.0 4.4 6 0 0 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 ORX95771.1 - 0.00038 20.3 0.1 0.0029 17.5 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1981 PF09324.10 ORX95771.1 - 0.1 12.5 5.0 0.22 11.4 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) DASH_Dad3 PF08656.10 ORX95771.1 - 0.19 11.9 0.7 15 5.7 0.0 3.4 3 0 0 3 3 3 0 DASH complex subunit Dad3 RNase_HII PF01351.18 ORX95772.1 - 1.4e-55 188.2 0.0 1.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII BATS PF06968.13 ORX95773.1 - 1.7e-18 66.5 0.0 8.3e-18 64.3 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ORX95773.1 - 2.9e-16 60.3 0.2 4.9e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TGF_beta PF00019.20 ORX95773.1 - 0.12 13.3 1.5 0.7 10.9 0.0 2.5 2 1 0 2 2 2 0 Transforming growth factor beta like domain FeoB_associated PF12669.7 ORX95773.1 - 8.1 6.9 7.9 4.4 7.8 1.0 2.4 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Amidohydro_1 PF01979.20 ORX95774.1 - 2.6e-16 59.9 0.6 9.3e-11 41.6 0.0 3.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ORX95774.1 - 3.1e-16 59.9 0.3 6.2e-07 29.2 0.3 3.0 2 1 0 3 3 3 2 Amidohydrolase family TatD_DNase PF01026.21 ORX95774.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase Urease_alpha PF00449.20 ORX95774.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain DnaJ_CXXCXGXG PF00684.19 ORX95775.1 - 0.057 13.8 7.5 0.11 12.9 1.3 2.3 1 1 1 2 2 2 0 DnaJ central domain CorA PF01544.18 ORX95776.1 - 5e-10 39.2 4.1 7.7e-10 38.6 4.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Aminotran_3 PF00202.21 ORX95777.1 - 2e-46 158.5 0.0 3.9e-45 154.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 ORX95777.1 - 1.6e-18 67.3 0.0 3.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain 4HBT PF03061.22 ORX95777.1 - 0.1 13.0 0.0 1.6 9.1 0.0 2.6 3 0 0 3 3 3 0 Thioesterase superfamily LSM PF01423.22 ORX95779.1 - 7.7e-23 80.0 0.1 8.4e-23 79.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain Lactamase_B PF00753.27 ORX95780.1 - 4.5e-13 49.7 0.3 1.1e-12 48.3 0.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_2 PF07719.17 ORX95780.1 - 1.2e-06 28.2 3.6 0.013 15.6 0.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORX95780.1 - 2.9e-05 23.7 0.3 0.044 13.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX95780.1 - 3.2e-05 23.5 0.6 0.042 13.5 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.6 ORX95780.1 - 0.0002 21.1 0.8 0.82 9.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 ORX95780.1 - 0.00079 19.5 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 ORX95780.1 - 0.0091 16.3 2.2 1.8 8.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 ORX95780.1 - 0.021 14.3 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TPR_14 PF13428.6 ORX95780.1 - 0.022 15.5 0.7 14 6.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 ORX95780.1 - 0.07 13.2 0.1 0.81 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 ORX95780.1 - 0.073 13.3 1.0 3.8 8.0 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Arrestin_C PF02752.22 ORX95781.1 - 4.6e-11 43.3 0.0 2.6e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX95781.1 - 6.2e-11 42.6 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Cyclin_N PF00134.23 ORX95782.1 - 4.1e-10 39.5 0.1 5.2e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX95782.1 - 3.7e-06 27.4 0.0 4.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin Rhodanese PF00581.20 ORX95784.1 - 6.6e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain JmjC PF02373.22 ORX95785.1 - 2.6e-27 95.5 0.1 7.1e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 ORX95785.1 - 2.5e-26 92.7 1.4 4.1e-26 92.0 1.4 1.4 1 0 0 1 1 1 1 PLU-1-like protein ARID PF01388.21 ORX95785.1 - 1.2e-19 70.7 0.0 3.4e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 ORX95785.1 - 3.5e-16 58.9 2.5 8.2e-16 57.7 2.5 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 ORX95785.1 - 1.1e-11 44.4 0.9 1.1e-11 44.4 0.9 2.2 2 0 0 2 2 2 1 PHD-finger zf-C5HC2 PF02928.16 ORX95785.1 - 1.6e-11 44.4 8.1 1.6e-11 44.4 8.1 2.2 2 0 0 2 2 2 1 C5HC2 zinc finger ADK_lid PF05191.14 ORX95785.1 - 0.058 13.4 1.3 0.16 12.0 1.3 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid Nudc_N PF14050.6 ORX95785.1 - 0.066 13.2 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. YlqD PF11068.8 ORX95807.1 - 0.00033 21.0 3.5 0.00033 21.0 3.5 2.3 1 1 1 2 2 2 1 YlqD protein TMF_TATA_bd PF12325.8 ORX95807.1 - 0.0076 16.5 4.3 0.0076 16.5 4.3 3.0 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 ORX95807.1 - 0.0078 16.5 14.5 0.015 15.5 7.6 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) SOGA PF11365.8 ORX95807.1 - 0.014 16.5 14.4 0.05 14.7 3.3 3.0 2 1 1 3 3 3 0 Protein SOGA Fib_alpha PF08702.10 ORX95807.1 - 0.014 15.6 4.3 0.014 15.6 4.3 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DMPK_coil PF08826.10 ORX95807.1 - 0.021 14.9 1.8 0.021 14.9 1.8 3.7 3 1 0 4 4 4 0 DMPK coiled coil domain like TMF_DNA_bd PF12329.8 ORX95807.1 - 0.051 13.6 0.9 0.051 13.6 0.9 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding TEP1_N PF05386.11 ORX95807.1 - 0.058 13.0 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 TEP1 N-terminal domain GAS PF13851.6 ORX95807.1 - 0.11 11.8 20.5 0.32 10.3 13.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4600 PF15372.6 ORX95807.1 - 0.18 12.3 11.3 0.82 10.1 7.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) PRKG1_interact PF15898.5 ORX95807.1 - 0.2 12.5 17.1 1.3 10.0 6.3 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 ORX95807.1 - 0.31 11.7 11.4 5.4 7.7 0.1 4.1 4 0 0 4 4 4 0 SlyX CK2S PF15011.6 ORX95807.1 - 0.42 10.5 14.2 0.44 10.4 3.1 2.8 1 1 1 2 2 2 0 Casein Kinase 2 substrate Fez1 PF06818.15 ORX95807.1 - 0.55 10.7 14.1 0.44 11.0 12.5 1.5 1 1 0 1 1 1 0 Fez1 Cep57_CLD_2 PF14197.6 ORX95807.1 - 0.92 9.6 17.7 1.3 9.2 1.6 4.4 4 2 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF4795 PF16043.5 ORX95807.1 - 1.1 8.8 13.0 2.2 7.8 13.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KELK PF15796.5 ORX95807.1 - 1.7 9.2 14.5 1.8 9.1 3.7 3.2 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RecG_N PF17190.4 ORX95807.1 - 3.4 8.5 8.6 3.1 8.6 0.7 3.1 2 1 1 3 3 3 0 RecG N-terminal helical domain DUF3450 PF11932.8 ORX95807.1 - 5.3 6.3 17.5 6.2 6.0 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 ORX95807.1 - 5.5 7.5 24.8 1.4 9.5 1.9 3.5 1 1 1 3 3 3 0 Apg6 coiled-coil region CCDC-167 PF15188.6 ORX95807.1 - 6.2 7.2 15.2 3.3 8.1 4.3 3.4 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Tup_N PF08581.10 ORX95807.1 - 7.5 6.9 13.9 5.4 7.4 4.0 3.4 2 1 2 4 4 4 0 Tup N-terminal UPF0242 PF06785.11 ORX95807.1 - 9.1 6.3 19.6 38 4.3 12.6 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 ORX95807.1 - 9.5 6.2 14.7 8.9 6.3 6.9 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion O-FucT PF10250.9 ORX95808.1 - 1.8e-06 27.9 1.1 0.00093 19.0 1.8 2.7 1 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase HMG_box PF00505.19 ORX95809.1 - 8.7e-26 90.1 11.1 5.2e-13 49.2 2.8 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX95809.1 - 5e-16 59.1 8.5 1.1e-07 32.4 1.9 2.9 3 0 0 3 3 3 2 HMG-box domain Protamine_like PF06382.11 ORX95809.1 - 6.1e-05 23.2 2.4 0.036 14.2 0.2 2.1 1 1 1 2 2 2 2 Protamine and protamine like DUF3106 PF11304.8 ORX95809.1 - 0.073 13.5 3.4 8.3 6.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) Imm58 PF15581.6 ORX95809.1 - 0.12 12.5 0.1 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 58 HMG_box_5 PF14887.6 ORX95809.1 - 0.2 11.6 3.2 0.97 9.5 0.5 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DHC PF09626.10 ORX95809.1 - 0.76 10.7 3.5 16 6.4 0.1 2.8 2 1 1 3 3 3 0 Dihaem cytochrome c PAS PF00989.25 ORX95810.1 - 6e-08 32.7 0.0 4.8e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORX95810.1 - 3.8e-07 30.3 0.0 0.0069 16.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORX95810.1 - 2.2e-05 24.6 0.0 6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORX95810.1 - 0.042 14.1 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 PAS fold PAS_2 PF08446.11 ORX95810.1 - 0.15 12.7 0.0 0.42 11.3 0.0 1.7 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.7 ORX95810.1 - 0.18 11.8 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain Epiglycanin_C PF14654.6 ORX95812.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region UEV PF05743.13 ORX95813.1 - 1.8e-34 118.2 0.3 2.9e-34 117.5 0.3 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 ORX95813.1 - 6.5e-24 83.7 0.1 1.5e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 Vps23 core domain Vps54_N PF10475.9 ORX95813.1 - 0.00041 19.7 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Corona_S2 PF01601.16 ORX95813.1 - 0.0011 17.6 0.7 0.0015 17.1 0.7 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein THOC7 PF05615.13 ORX95813.1 - 0.0036 17.6 0.2 0.0067 16.7 0.2 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 Exonuc_VII_L PF02601.15 ORX95813.1 - 0.019 14.6 0.2 0.025 14.1 0.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2482 PF10655.9 ORX95813.1 - 0.02 15.4 0.7 0.045 14.2 0.7 1.6 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) UQ_con PF00179.26 ORX95813.1 - 0.032 13.9 0.3 0.059 13.0 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme YlqD PF11068.8 ORX95813.1 - 0.033 14.5 3.7 0.064 13.6 3.7 1.4 1 0 0 1 1 1 0 YlqD protein Spc42p PF11544.8 ORX95813.1 - 0.057 13.4 1.6 0.16 12.0 1.6 1.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p TPR_MLP1_2 PF07926.12 ORX95813.1 - 0.16 12.1 6.0 0.27 11.3 6.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 ORX95813.1 - 0.3 11.1 1.2 0.81 9.7 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YscO PF07321.12 ORX95813.1 - 0.53 10.2 4.3 3.3 7.6 1.1 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO bZIP_1 PF00170.21 ORX95813.1 - 0.77 9.9 5.8 0.69 10.1 1.7 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF5595 PF18077.1 ORX95813.1 - 3.9 7.6 5.9 16 5.7 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) Homeodomain PF00046.29 ORX95814.1 - 1.3e-17 63.3 4.6 1.5e-17 63.2 4.6 1.0 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 ORX95814.1 - 0.0026 17.6 0.0 0.0036 17.1 0.0 1.3 1 1 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 ORX95814.1 - 0.0067 16.2 0.0 0.059 13.2 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.11 ORX95814.1 - 0.0091 15.9 0.5 0.016 15.1 0.1 1.6 2 0 0 2 2 2 1 Homeobox KN domain HTH_28 PF13518.6 ORX95814.1 - 0.021 14.9 0.1 3.8 7.7 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain DAGAT PF03982.13 ORX95815.1 - 3.4e-75 252.7 0.0 4.3e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UPF0014 PF03649.13 ORX95816.1 - 2.9e-74 249.5 18.2 3.6e-74 249.2 18.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) OATP PF03137.20 ORX95816.1 - 2 6.6 11.5 0.035 12.4 0.8 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_5_2 PF16079.5 ORX95816.1 - 4.1 7.8 10.5 1.4 9.3 2.5 3.4 2 2 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V TssN PF17555.2 ORX95816.1 - 4.9 6.5 5.8 8.5 5.7 5.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN Cyclin PF08613.11 ORX95817.1 - 2.4e-13 50.8 0.1 2.8e-13 50.5 0.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX95817.1 - 1.2e-09 38.0 0.1 1.4e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain 6PF2K PF01591.18 ORX95817.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RhoGAP PF00620.27 ORX95818.1 - 6e-44 149.5 0.0 6e-44 149.5 0.0 2.4 4 0 0 4 4 4 1 RhoGAP domain FCH PF00611.23 ORX95818.1 - 4.1e-06 27.0 0.1 4.1e-06 27.0 0.1 2.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain CHD5 PF04420.14 ORX95818.1 - 0.45 10.4 2.7 1.5 8.7 2.7 2.0 1 0 0 1 1 1 0 CHD5-like protein DUF2852 PF11014.8 ORX95818.1 - 1.3 9.2 8.2 5.8 7.1 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2852) Sec7 PF01369.20 ORX95819.1 - 7.8e-68 227.8 1.5 1.6e-67 226.8 0.2 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 ORX95819.1 - 4.4e-41 140.4 6.2 4.4e-41 140.4 6.2 4.1 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORX95819.1 - 5.3e-38 128.8 15.3 2.8e-35 120.0 0.7 6.7 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 ORX95819.1 - 1.6e-11 44.2 17.5 2e-11 43.9 1.1 6.1 5 2 1 6 6 6 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 ORX95819.1 - 0.0092 16.1 0.9 12 6.0 0.1 3.9 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1539) PRKCSH PF07915.13 ORX95820.1 - 3.5e-13 50.4 2.4 7.6e-13 49.3 2.4 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 ORX95820.1 - 0.00019 21.2 2.5 0.00069 19.3 2.5 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein CoA_transf_3 PF02515.17 ORX95821.1 - 5.8e-70 236.2 0.0 2e-69 234.5 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III Kinesin PF00225.23 ORX95822.1 - 7.7e-118 393.2 0.2 8.8e-118 393.0 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX95822.1 - 2.4e-27 95.7 0.1 4.6e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding Acyl_transf_1 PF00698.21 ORX95822.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase domain Arrestin_C PF02752.22 ORX95823.1 - 5.6e-06 26.8 1.0 8e-06 26.3 1.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Herpes_UL56 PF04534.12 ORX95823.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Mem_trans PF03547.18 ORX95824.1 - 5.2e-21 74.5 9.0 8e-21 73.9 9.0 1.2 1 0 0 1 1 1 1 Membrane transport protein Ribosomal_L50 PF10501.9 ORX95824.1 - 0.098 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Glyco_hydro_16 PF00722.21 ORX95825.1 - 6e-33 113.8 3.6 6e-33 113.8 3.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Chondroitinas_B PF14592.6 ORX95839.1 - 9.5e-34 117.0 1.3 1.2e-33 116.7 1.3 1.2 1 0 0 1 1 1 1 Chondroitinase B Beta_helix PF13229.6 ORX95839.1 - 4.5e-11 42.8 29.0 1.2e-06 28.5 8.4 3.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 ORX95839.1 - 6e-07 29.0 9.3 2.5e-06 26.9 9.2 2.0 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 ORX95839.1 - 0.23 10.8 6.7 0.45 9.8 6.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1565) Glyco_hydro_47 PF01532.20 ORX95840.1 - 5.8e-122 407.9 0.7 6.8e-122 407.6 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4951 PF16309.5 ORX95840.1 - 0.15 12.2 0.2 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) bZIP_2 PF07716.15 ORX95841.1 - 2.5e-12 46.7 11.2 4.4e-12 45.9 11.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX95841.1 - 0.00057 19.9 9.7 0.0012 18.9 9.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 ORX95841.1 - 0.012 15.8 2.2 0.021 15.0 2.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF1319 PF07028.11 ORX95841.1 - 0.034 14.3 0.8 0.056 13.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Syntaxin-6_N PF09177.11 ORX95841.1 - 0.38 11.3 5.9 0.92 10.1 4.4 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FAP PF07174.11 ORX95842.1 - 0.0074 15.8 6.5 0.008 15.7 6.5 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) CBM_19 PF03427.13 ORX95842.1 - 0.014 15.4 10.5 0.014 15.4 10.5 2.6 1 1 1 2 2 2 0 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORX95842.1 - 0.11 12.7 8.7 0.55 10.4 8.7 2.0 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain CD24 PF14984.6 ORX95842.1 - 0.17 12.1 0.2 0.17 12.1 0.2 3.0 2 1 0 2 2 2 0 CD24 protein CBM_14 PF01607.24 ORX95843.1 - 0.06 13.5 5.3 0.19 11.9 5.5 1.8 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain Med13_C PF06333.12 ORX95843.1 - 0.39 9.9 9.5 0.45 9.7 9.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Raftlin PF15250.6 ORX95843.1 - 0.83 8.3 2.7 1 8.1 2.7 1.1 1 0 0 1 1 1 0 Raftlin NADHdh_A3 PF14987.6 ORX95843.1 - 6.4 7.2 6.2 0.34 11.2 0.4 1.9 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 SPX PF03105.19 ORX95843.1 - 6.9 6.5 11.5 7.5 6.4 11.5 1.0 1 0 0 1 1 1 0 SPX domain CBM_14 PF01607.24 ORX95844.1 - 0.014 15.6 4.1 0.032 14.4 4.2 1.6 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain RR_TM4-6 PF06459.12 ORX95847.1 - 1.8 8.3 4.4 2.4 7.9 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CBM_14 PF01607.24 ORX95848.1 - 0.085 13.0 4.0 0.17 12.0 4.0 1.6 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain RTBV_P12 PF06361.11 ORX95848.1 - 0.26 11.7 5.9 0.19 12.2 0.4 2.3 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein SRF-TF PF00319.18 ORX95849.1 - 2.2e-21 75.1 0.1 3.5e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Vac7 PF12751.7 ORX95849.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Ribosomal_L6 PF00347.23 ORX95850.1 - 1.6e-26 92.7 0.4 4.1e-15 56.2 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 Rotamase PF00639.21 ORX95851.1 - 1.5e-23 83.5 0.0 2.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ORX95851.1 - 6.6e-17 62.1 0.0 8.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 ORX95851.1 - 2e-09 37.3 3.8 2.5e-09 37.1 1.5 2.1 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 ORX95851.1 - 0.00043 21.1 0.0 0.00069 20.5 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Cyto_heme_lyase PF01265.17 ORX95852.1 - 2.8e-57 194.5 8.8 3e-56 191.2 8.8 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-C2H2 PF00096.26 ORX95853.1 - 5.6e-14 51.7 9.2 2.9e-07 30.6 1.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX95853.1 - 1.2e-09 38.2 7.5 2.2e-05 24.9 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX95853.1 - 1.2e-08 34.9 13.1 1.7e-07 31.3 1.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX95853.1 - 2.1e-08 34.3 0.8 0.00016 21.9 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX95853.1 - 2.1e-07 31.0 0.7 0.0011 19.2 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX95853.1 - 4.8e-06 26.4 3.4 0.00028 20.8 0.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX95853.1 - 0.0017 18.1 1.1 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-BED PF02892.15 ORX95853.1 - 0.012 15.6 3.1 0.17 11.9 3.1 2.1 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_2 PF12756.7 ORX95853.1 - 0.067 13.5 0.9 0.17 12.2 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 ORX95853.1 - 0.089 12.7 0.3 0.089 12.7 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 ORX95853.1 - 0.47 10.2 6.2 7 6.5 0.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Mito_carr PF00153.27 ORX95854.1 - 3.4e-42 142.3 4.0 6.5e-13 48.4 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX95854.1 - 0.0069 15.6 1.2 1.8 7.6 0.0 2.5 2 0 0 2 2 2 2 Gammaproteobacterial serine protease YtxH PF12732.7 ORX95854.1 - 0.033 14.7 0.2 0.22 12.1 0.2 2.3 1 1 0 1 1 1 0 YtxH-like protein zf-CCCH PF00642.24 ORX95855.1 - 1.1e-15 57.1 19.5 9.5e-09 35.0 5.3 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORX95855.1 - 1.4e-06 27.9 16.2 0.00015 21.5 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORX95855.1 - 4e-06 26.7 17.3 0.00016 21.6 2.8 2.6 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 ORX95855.1 - 0.0019 18.6 9.8 0.021 15.3 0.5 2.7 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORX95855.1 - 0.019 15.6 12.8 0.46 11.2 3.7 2.0 1 1 1 2 2 2 0 Torus domain Defensin_int PF17858.1 ORX95855.1 - 0.063 13.3 3.6 0.081 12.9 1.9 1.8 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-HC5HC2H_2 PF13832.6 ORX95856.1 - 2.3e-16 59.9 11.3 2.9e-16 59.6 2.7 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 ORX95856.1 - 1.2e-11 43.9 2.4 1.2e-11 43.9 2.4 3.4 4 1 0 4 4 4 1 PHD-finger PHD PF00628.29 ORX95856.1 - 1.4e-11 44.1 5.5 1.4e-11 44.1 5.5 3.9 3 1 1 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.6 ORX95856.1 - 8.5e-08 32.4 5.3 8.5e-08 32.4 5.3 3.6 2 2 0 2 2 2 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 ORX95856.1 - 0.001 18.9 3.6 0.001 18.9 3.6 3.6 3 1 0 3 3 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 ORX95856.1 - 0.0048 16.5 2.1 0.0048 16.5 2.1 2.5 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 ORX95856.1 - 0.005 17.0 1.0 0.005 17.0 1.0 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger C1_1 PF00130.22 ORX95856.1 - 0.024 14.5 1.6 0.024 14.5 1.6 4.4 2 2 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 ORX95856.1 - 0.03 14.3 13.6 0.056 13.4 3.1 2.5 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 ORX95856.1 - 0.032 14.6 1.7 0.032 14.6 1.7 4.1 4 0 0 4 4 4 0 C1 domain zf-PARP PF00645.18 ORX95856.1 - 2.9 8.8 9.0 1.2 10.1 2.2 2.6 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Whi5 PF08528.11 ORX95857.1 - 2.3e-08 33.4 0.0 4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Ras PF00071.22 ORX95858.1 - 5.2e-55 185.5 0.2 6.1e-55 185.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95858.1 - 1.3e-20 73.8 0.1 2.1e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95858.1 - 1.2e-07 31.3 0.1 1.5e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX95858.1 - 0.00025 20.6 0.9 0.0017 18.0 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX95858.1 - 0.00059 19.8 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX95858.1 - 0.034 14.2 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX95858.1 - 0.04 13.5 0.2 0.62 9.6 0.2 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B CbiA PF01656.23 ORX95858.1 - 0.048 13.7 0.2 0.15 12.1 0.2 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 ORX95858.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX95858.1 - 0.17 12.3 0.1 0.28 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_S5 PF00333.20 ORX95859.1 - 4.8e-29 100.1 0.5 4.8e-29 100.1 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX95859.1 - 1.2e-25 88.7 0.1 2.1e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORX95859.1 - 0.49 11.0 8.5 1 10.0 8.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ATP-synt_C PF00137.21 ORX95860.1 - 1.8e-29 101.9 24.6 2.1e-22 79.2 13.6 2.3 2 0 0 2 2 2 2 ATP synthase subunit C DUF4389 PF14333.6 ORX95860.1 - 3 7.8 6.1 9.8 6.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) ATP-synt_C PF00137.21 ORX95861.1 - 3.4e-33 113.8 34.6 4e-22 78.3 13.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF229 PF02995.17 ORX95862.1 - 4.9e-33 114.5 0.0 1.5e-31 109.6 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 ORX95862.1 - 0.0031 16.9 0.0 0.0078 15.6 0.0 1.6 1 1 1 2 2 2 1 Sulfatase TB2_DP1_HVA22 PF03134.19 ORX95863.1 - 1.9e-28 98.2 6.0 3e-28 97.5 6.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Med21 PF11221.8 ORX95864.1 - 6.8e-30 104.2 2.5 1e-29 103.6 2.5 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex BLM10_mid PF16507.5 ORX95864.1 - 0.015 14.0 0.2 0.016 13.9 0.2 1.0 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region Med9 PF07544.13 ORX95864.1 - 0.017 15.2 0.8 0.1 12.7 0.2 2.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PhoU PF01895.19 ORX95864.1 - 0.1 13.0 0.1 0.8 10.2 0.1 2.2 2 1 0 2 2 2 0 PhoU domain Methyltransf_23 PF13489.6 ORX95888.1 - 8.5e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 ORX95889.1 - 7.3e-37 127.1 53.5 1.5e-33 116.2 29.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX95889.1 - 4.1e-12 45.7 4.7 4.1e-12 45.7 4.7 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORX95889.1 - 3.7e-05 22.4 0.6 6e-05 21.7 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ORX95889.1 - 0.00015 21.2 0.8 0.00015 21.2 0.8 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORX95889.1 - 0.0028 16.6 0.1 0.0028 16.6 0.1 2.8 1 1 0 2 2 2 1 MFS_1 like family DUF2530 PF10745.9 ORX95889.1 - 0.11 12.7 1.6 0.61 10.4 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) GCFC PF07842.12 ORX95891.1 - 2.3e-83 280.0 13.8 3.3e-83 279.5 13.8 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 ORX95891.1 - 2e-13 50.0 0.2 4.6e-13 48.8 0.2 1.6 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 ORX95891.1 - 1.1e-11 45.1 10.5 1.1e-11 45.1 10.5 2.7 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 ORX95891.1 - 4e-07 30.0 3.4 4.5e-06 26.7 0.2 3.3 3 1 1 4 4 4 1 G-patch domain AAA_13 PF13166.6 ORX95891.1 - 6.3 5.3 7.8 0.89 8.1 3.5 1.7 2 1 0 2 2 2 0 AAA domain Tubulin PF00091.25 ORX95894.1 - 1.3e-69 234.4 0.0 1.9e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORX95894.1 - 3.3e-51 172.7 0.0 5.4e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORX95894.1 - 0.00023 20.9 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Uds1 PF15456.6 ORX95895.1 - 3.3e-09 37.0 4.6 3.3e-09 37.0 4.6 2.8 2 1 0 2 2 2 1 Up-regulated During Septation MnmE_helical PF12631.7 ORX95895.1 - 0.036 14.2 7.6 0.12 12.5 7.1 1.9 2 0 0 2 2 2 0 MnmE helical domain RD3 PF14473.6 ORX95895.1 - 0.045 13.6 3.9 0.14 12.0 3.9 1.7 1 0 0 1 1 1 0 RD3 protein TetR_C_24 PF17932.1 ORX95895.1 - 0.87 9.9 3.0 20 5.5 0.1 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HR1 PF02185.16 ORX95895.1 - 6.5 6.9 11.1 0.16 12.1 1.9 3.0 2 0 0 2 2 2 0 Hr1 repeat Chs7 PF12271.8 ORX95896.1 - 1.3e-94 316.8 13.1 1.5e-94 316.6 13.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Peptidase_M14 PF00246.24 ORX95897.1 - 3e-70 237.3 0.0 3.6e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORX95897.1 - 0.0011 19.4 0.1 0.0024 18.2 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Arf PF00025.21 ORX95898.1 - 9.1e-80 266.2 0.1 1e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX95898.1 - 2.6e-14 53.4 0.0 3.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORX95898.1 - 4e-14 52.4 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORX95898.1 - 2.7e-13 49.8 0.9 2.4e-09 36.8 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORX95898.1 - 5.9e-13 48.7 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORX95898.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX95898.1 - 2.3e-06 27.6 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORX95898.1 - 0.0068 15.7 0.3 0.022 14.1 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Sec20 PF03908.13 ORX95899.1 - 3e-24 84.7 2.0 3e-24 84.7 2.0 3.0 2 1 0 2 2 2 1 Sec20 DUF4407 PF14362.6 ORX95899.1 - 0.01 15.2 6.1 0.019 14.3 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAS_7 PF12860.7 ORX95899.1 - 0.023 14.8 0.7 0.075 13.2 0.5 1.9 1 1 0 1 1 1 0 PAS fold Baculo_11_kDa PF06143.11 ORX95899.1 - 0.13 11.8 0.4 0.99 9.0 0.1 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family Ost4 PF10215.9 ORX95899.1 - 0.78 9.6 2.6 1.7 8.5 2.6 1.6 1 0 0 1 1 1 0 Oligosaccaryltransferase Exonuc_VII_L PF02601.15 ORX95899.1 - 1.2 8.6 12.1 2.2 7.7 12.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Z1 PF10593.9 ORX95899.1 - 1.8 8.0 8.9 1.3 8.4 6.7 1.9 1 1 1 2 2 2 0 Z1 domain Homeodomain PF00046.29 ORX95900.1 - 1.4e-18 66.5 1.8 1.7e-18 66.2 1.8 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX95900.1 - 0.0043 16.9 0.2 0.0077 16.1 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Phe_tRNA-synt_N PF02912.18 ORX95900.1 - 0.015 15.2 1.1 0.018 15.0 1.1 1.3 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Homez PF11569.8 ORX95900.1 - 0.13 11.8 0.1 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez IPK PF03770.16 ORX95901.1 - 2.6e-47 161.2 0.0 3.7e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase FPN1 PF06963.12 ORX95902.1 - 1.1e-104 350.4 17.7 1.3e-104 350.2 17.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) RNB PF00773.19 ORX95903.1 - 5.6e-105 351.3 0.0 1.3e-104 350.1 0.0 1.6 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 ORX95903.1 - 2.3e-23 82.0 0.0 5.4e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORX95903.1 - 1.1e-19 70.5 0.0 2.8e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_S1 PF17215.3 ORX95903.1 - 2.4e-05 24.2 2.3 0.00021 21.2 0.0 3.5 5 0 0 5 5 5 1 S1 domain Rrp44_CSD1 PF17216.3 ORX95903.1 - 3e-05 23.8 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 ORX95903.1 - 0.0037 17.4 0.0 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 Cold shock domain Myf5 PF12232.8 ORX95903.1 - 0.035 14.9 10.4 0.11 13.3 10.4 1.8 1 0 0 1 1 1 0 Myogenic determination factor 5 Sds3 PF08598.11 ORX95904.1 - 1.4e-19 71.0 20.5 1.6e-19 70.8 20.5 1.1 1 0 0 1 1 1 1 Sds3-like HEPN_RiboL-PSP PF18735.1 ORX95904.1 - 0.065 13.1 5.9 0.11 12.4 5.9 1.4 1 1 0 1 1 1 0 RiboL-PSP-HEPN Cytadhesin_P30 PF07271.11 ORX95904.1 - 0.57 9.7 3.0 1.1 8.8 3.0 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 TMPIT PF07851.13 ORX95904.1 - 5.8 6.1 8.7 8.3 5.6 8.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein Ras PF00071.22 ORX95905.1 - 3.4e-52 176.3 1.0 4e-52 176.1 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX95905.1 - 1.6e-35 121.9 0.4 5e-35 120.3 0.2 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX95905.1 - 1.8e-16 60.1 0.3 2.3e-16 59.7 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX95905.1 - 1.8e-05 24.2 0.3 2.2e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX95905.1 - 4.2e-05 23.6 0.1 9.7e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORX95905.1 - 0.00012 21.6 0.1 0.00015 21.3 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORX95905.1 - 0.00016 21.6 0.8 0.082 12.8 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORX95905.1 - 0.00018 21.1 0.4 0.0005 19.7 0.1 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORX95905.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 ORX95905.1 - 0.03 14.1 0.1 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YwhD PF08741.10 ORX95905.1 - 0.079 12.6 0.2 0.2 11.3 0.1 1.6 1 1 1 2 2 2 0 YwhD family AAA_33 PF13671.6 ORX95905.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain TRP PF06011.12 ORX95906.1 - 3.4e-24 85.4 32.5 3.4e-22 78.8 27.0 2.2 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 ORX95906.1 - 1.4e-05 25.5 0.1 2.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 ML domain TMEMspv1-c74-12 PF11044.8 ORX95906.1 - 0.054 13.5 1.4 0.22 11.6 1.4 2.0 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Rav1p_C PF12234.8 ORX95907.1 - 3.1e-115 386.0 0.1 3.8e-115 385.7 0.1 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Cas9_a PF18470.1 ORX95907.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain DUF2013 PF09431.10 ORX95908.1 - 1e-45 155.3 3.9 1e-45 155.3 3.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) DUF2428 PF10350.9 ORX95908.1 - 0.046 13.0 1.3 0.084 12.1 0.8 1.7 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) DUF3385 PF11865.8 ORX95908.1 - 0.35 10.8 3.3 13 5.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) Adap_comp_sub PF00928.21 ORX95909.1 - 1e-48 166.0 0.1 1.3e-48 165.7 0.1 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MHC_II_alpha PF00993.20 ORX95909.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Pkinase PF00069.25 ORX95910.1 - 1.2e-73 247.7 0.0 1.8e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95910.1 - 5.7e-34 117.6 0.0 9.9e-34 116.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX95910.1 - 0.00012 21.5 0.4 1.3 8.2 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 ORX95910.1 - 0.034 14.1 0.0 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX95910.1 - 0.045 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Solute_trans_a PF03619.16 ORX95911.1 - 2.8e-98 328.7 12.2 3.4e-98 328.4 12.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1462 PF07315.11 ORX95911.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) ICMT PF04140.14 ORX95912.1 - 3.3e-26 91.5 1.7 7.1e-26 90.5 1.7 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORX95912.1 - 1.4e-13 51.2 1.4 1.4e-13 51.2 1.4 2.7 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 ORX95912.1 - 2.2e-05 24.1 0.7 2.8e-05 23.8 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Methyltransf_23 PF13489.6 ORX95913.1 - 2.5e-10 40.4 0.0 3.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX95913.1 - 0.0001 22.1 0.0 0.00075 19.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX95913.1 - 0.00012 22.8 0.0 0.00039 21.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ORX95913.1 - 0.00061 19.5 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) CheR PF01739.18 ORX95913.1 - 0.022 14.3 0.0 0.92 9.0 0.0 2.1 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 ORX95913.1 - 0.048 14.4 0.0 0.22 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain CBAH PF02275.18 ORX95914.1 - 0.02 14.6 0.2 0.027 14.1 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Homeodomain PF00046.29 ORX95944.1 - 7.1e-20 70.6 4.5 7.6e-20 70.5 4.5 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX95944.1 - 0.0017 18.2 0.3 0.0023 17.8 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 ORX95946.1 - 1.2e-12 47.5 11.8 7e-06 26.2 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX95946.1 - 5.8e-12 45.5 11.0 1.4e-07 31.6 1.6 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX95946.1 - 1.9e-09 37.6 9.7 0.00052 20.6 2.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95946.1 - 0.00012 22.2 2.0 0.041 14.2 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX95946.1 - 0.024 15.1 4.1 0.048 14.1 1.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX95946.1 - 0.039 14.0 13.2 0.049 13.7 1.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3404 PF11884.8 ORX95946.1 - 0.088 12.0 0.9 0.28 10.4 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3404) zf-C2H2 PF00096.26 ORX95947.1 - 6.3e-14 51.6 9.0 1.5e-06 28.3 2.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX95947.1 - 5.8e-12 45.5 11.3 6.3e-10 39.0 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX95947.1 - 2.1e-10 40.5 7.1 0.00012 22.6 1.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95947.1 - 0.0001 22.5 1.4 0.0066 16.7 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX95947.1 - 0.00044 20.2 9.1 0.0087 16.0 0.7 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX95947.1 - 0.00068 19.9 0.9 0.0064 16.9 0.3 2.3 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORX95947.1 - 0.008 15.9 6.4 0.2 11.5 0.4 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 ORX95947.1 - 0.019 14.6 1.4 0.72 9.5 0.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HC_2 PF13913.6 ORX95947.1 - 0.024 14.5 9.3 0.57 10.2 3.4 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 ORX95947.1 - 0.058 13.7 3.1 4.4 7.7 0.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 ORX95947.1 - 0.077 12.8 0.1 8.2 6.4 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 ORX95947.1 - 0.16 12.3 1.6 1.2 9.5 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 ORX95947.1 - 0.51 10.2 5.3 0.33 10.8 0.7 2.1 1 1 1 2 2 2 0 GAGA factor Pkinase PF00069.25 ORX95948.1 - 3.1e-56 190.7 0.1 4.8e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95948.1 - 1.6e-40 139.0 0.1 2.5e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORX95948.1 - 0.00032 20.8 0.2 0.00077 19.6 0.2 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 ORX95948.1 - 0.016 14.0 0.1 0.038 12.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Carb_kinase PF01256.17 ORX95949.1 - 6.1e-59 199.4 0.0 8.1e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 ORX95949.1 - 1.8e-06 27.5 0.2 6.7e-06 25.7 0.1 1.8 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase HK PF02110.15 ORX95949.1 - 0.00021 20.7 0.6 0.00046 19.7 0.6 1.5 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Ribosomal_S21e PF01249.18 ORX95950.1 - 3.2e-40 136.1 0.0 3.6e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4325 PF14213.6 ORX95950.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Sec2p PF06428.11 ORX95951.1 - 2.4e-19 69.1 13.2 2.4e-19 69.1 13.2 2.8 2 2 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4718 PF15842.5 ORX95951.1 - 0.013 15.3 0.3 0.028 14.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) KAP_NTPase PF07693.14 ORX95951.1 - 0.22 10.7 8.3 0.32 10.2 8.3 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MTCP1 PF08991.10 ORX95952.1 - 2.2e-06 27.8 3.9 3e-06 27.4 3.9 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 ORX95952.1 - 6.2e-06 26.2 8.2 9.7e-06 25.6 8.2 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 ORX95952.1 - 0.0006 20.1 5.0 0.00083 19.6 5.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 TAP_C PF03943.13 ORX95952.1 - 0.0034 17.0 0.4 0.0061 16.2 0.4 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NDUF_B7 PF05676.13 ORX95952.1 - 0.0041 16.8 5.4 0.0052 16.5 5.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 ORX95952.1 - 0.11 12.8 8.2 0.34 11.2 8.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) ARL2_Bind_BART PF11527.8 ORX95952.1 - 0.13 12.4 2.6 0.42 10.7 0.9 1.9 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART Pkinase PF00069.25 ORX95953.1 - 4.7e-54 183.5 0.0 7.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX95953.1 - 9.7e-28 97.1 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORX95953.1 - 8.8e-06 25.2 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX95953.1 - 0.00094 19.2 0.1 0.0041 17.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX95953.1 - 0.0012 18.5 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 ORX95953.1 - 0.0046 15.8 1.1 0.0094 14.8 1.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORX95953.1 - 0.0074 15.9 0.7 0.23 11.1 0.7 2.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORX95953.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 ORX95953.1 - 0.095 11.6 0.1 0.095 11.6 0.1 2.1 1 1 1 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 ORX95953.1 - 0.095 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Hpt PF01627.23 ORX95954.1 - 3e-12 46.6 0.1 4.5e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Hpt domain Toxin_trans PF07952.12 ORX95954.1 - 0.027 13.6 0.1 0.034 13.2 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain zf-C2H2 PF00096.26 ORX95955.1 - 3.7e-11 42.8 13.3 7e-06 26.2 3.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX95955.1 - 4.7e-09 36.3 11.6 6.6e-06 26.3 2.5 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.7 ORX95955.1 - 6e-09 36.0 1.1 2.9e-05 24.3 0.4 2.5 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORX95955.1 - 9.1e-09 35.4 11.0 4.9e-05 23.8 2.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX95955.1 - 1.8e-08 34.1 5.5 1.6e-06 27.9 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX95955.1 - 1.5e-06 28.3 5.4 0.00038 20.7 0.3 2.6 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ORX95955.1 - 0.0054 16.7 6.0 0.11 12.6 1.1 2.2 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 ORX95955.1 - 0.013 15.8 2.5 0.13 12.6 0.9 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX95955.1 - 0.015 15.1 8.1 0.3 10.9 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 ORX95955.1 - 0.24 11.2 10.3 1.3 8.9 2.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Palm_thioest PF02089.15 ORX95956.1 - 1.8e-06 28.0 0.0 3.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ORX95956.1 - 1.9e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORX95956.1 - 1.7e-05 24.7 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORX95956.1 - 0.00024 20.9 0.1 0.0084 15.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 ORX95956.1 - 0.0022 17.2 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 ORX95956.1 - 0.031 13.6 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 ORX95956.1 - 0.1 13.2 0.2 0.19 12.3 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 ORX95957.1 - 9.4e-136 453.3 26.7 1.1e-135 453.1 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX95957.1 - 3.6e-34 118.2 53.8 2.1e-26 92.7 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5134 PF17197.4 ORX95957.1 - 0.21 11.5 3.7 0.73 9.7 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) DUF2834 PF11196.8 ORX95957.1 - 4.7 7.6 9.4 2.2 8.7 1.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) Hexokinase_1 PF00349.21 ORX95985.1 - 2.3e-39 135.4 0.0 3.1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 ORX95985.1 - 2.5e-28 99.2 0.0 3.6e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Ceramidase PF05875.12 ORX95985.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ceramidase Nairo_nucleo PF02477.15 ORX95985.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein Syntaxin PF00804.25 ORX95986.1 - 3.4e-33 115.0 13.4 3.4e-33 115.0 13.4 1.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 ORX95986.1 - 1.2e-13 50.8 1.2 3e-13 49.5 1.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 ORX95986.1 - 7e-05 23.1 5.3 7e-05 23.1 5.3 2.7 2 1 0 2 2 2 1 Syntaxin-like protein DUF4094 PF13334.6 ORX95986.1 - 0.016 15.6 2.3 0.039 14.4 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DUF1673 PF07895.11 ORX95986.1 - 0.038 13.7 0.7 0.06 13.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3671 PF12420.8 ORX95986.1 - 0.047 13.8 0.5 0.12 12.5 0.1 1.9 2 0 0 2 2 1 0 Protein of unknown function MinE PF03776.14 ORX95986.1 - 0.11 12.6 1.8 0.31 11.1 0.2 2.4 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE TPR_19 PF14559.6 ORX95986.1 - 0.12 12.9 0.2 0.58 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat IL11 PF07400.11 ORX95986.1 - 0.12 12.0 1.5 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Interleukin 11 DASH_Dam1 PF08653.10 ORX95986.1 - 0.16 11.8 7.0 0.29 11.0 0.3 3.3 2 2 2 4 4 4 0 DASH complex subunit Dam1 Allexi_40kDa PF05549.11 ORX95986.1 - 0.23 10.9 6.3 2.6 7.5 0.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Spectrin PF00435.21 ORX95986.1 - 0.33 11.5 10.0 1.1 9.8 0.5 3.0 3 1 0 3 3 3 0 Spectrin repeat DUF2116 PF09889.9 ORX95986.1 - 0.61 10.1 2.8 1.7 8.7 2.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SKA1 PF07160.12 ORX95986.1 - 0.72 9.6 13.3 0.17 11.7 4.4 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 LETM1 PF07766.13 ORX95986.1 - 1.1 8.6 8.1 0.15 11.4 1.6 2.4 1 1 2 3 3 3 0 LETM1-like protein MCPsignal PF00015.21 ORX95986.1 - 1.1 9.0 8.5 0.38 10.5 1.6 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.14 ORX95986.1 - 1.4 8.5 16.1 0.042 13.6 5.1 2.4 2 1 0 2 2 2 0 Laminin Domain I DUF3106 PF11304.8 ORX95986.1 - 1.8 9.1 9.4 3.5 8.1 1.7 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3106) LMBR1 PF04791.16 ORX95986.1 - 2.4 6.9 12.9 9.5 5.0 12.8 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein DASH_Dad1 PF08649.10 ORX95986.1 - 3.4 7.9 7.3 0.67 10.2 0.5 3.2 3 1 0 3 3 3 0 DASH complex subunit Dad1 Baculo_PEP_C PF04513.12 ORX95986.1 - 3.5 7.7 12.7 2 8.4 3.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 ORX95986.1 - 4.4 8.1 13.2 8 7.2 3.0 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cauli_AT PF03233.13 ORX95986.1 - 4.8 7.1 8.4 1.5 8.7 2.3 2.6 2 1 0 2 2 2 0 Aphid transmission protein Plk4_PB2 PF18409.1 ORX95986.1 - 5.2 7.8 6.4 11 6.8 0.1 3.2 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Hydrolase_4 PF12146.8 ORX95987.1 - 2e-15 56.7 0.1 6.3e-14 51.8 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX95987.1 - 3.3e-11 43.3 0.1 3e-10 40.2 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX95987.1 - 1e-07 32.8 0.0 1.4e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX95987.1 - 7.6e-07 28.8 0.1 7.1e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 ORX95987.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1749 PF08538.10 ORX95987.1 - 0.00034 19.8 0.1 0.014 14.5 0.1 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1749) FSH1 PF03959.13 ORX95987.1 - 0.00082 19.1 0.0 0.0059 16.3 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 ORX95987.1 - 0.00085 19.0 0.1 1.1 8.8 0.0 2.4 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 ORX95987.1 - 0.0042 16.7 0.0 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF915 PF06028.11 ORX95987.1 - 0.015 14.7 0.3 0.09 12.1 0.3 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 ORX95987.1 - 0.03 13.8 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.16 ORX95987.1 - 0.036 13.8 0.1 8.2 6.2 0.0 3.0 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase Lung_7-TM_R PF06814.13 ORX95988.1 - 2.3e-64 217.5 20.7 2.9e-64 217.2 20.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Frag1 PF10277.9 ORX95988.1 - 3.8 7.0 19.3 0.97 8.9 14.9 2.2 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family ATP1G1_PLM_MAT8 PF02038.16 ORX95988.1 - 7.7 6.0 5.9 0.84 9.1 0.6 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family GST_N_2 PF13409.6 ORX95989.1 - 6.6e-10 39.1 0.1 1.5e-09 38.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORX95989.1 - 7.9e-10 39.0 0.0 1.7e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX95989.1 - 1.9e-05 24.6 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX95989.1 - 0.00034 20.9 0.0 0.00072 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ploopntkinase3 PF18751.1 ORX95989.1 - 0.052 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PPTA PF01239.22 ORX95989.1 - 0.12 12.1 4.0 0.25 11.1 0.8 2.7 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat S-AdoMet_synt_C PF02773.16 ORX95990.1 - 2.2e-70 235.0 0.1 4.4e-70 234.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORX95990.1 - 5.3e-49 165.4 0.0 9.3e-49 164.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORX95990.1 - 4.3e-39 133.2 0.1 2.2e-37 127.7 0.1 2.5 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORX95990.1 - 0.049 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) NDUF_B4 PF07225.12 ORX95991.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SIP PF04954.13 ORX95992.1 - 0.055 14.0 0.0 0.075 13.5 0.0 1.2 1 0 0 1 1 1 0 Siderophore-interacting protein ABC2_membrane PF01061.24 ORX95993.1 - 8.5e-84 280.2 54.6 6.5e-48 162.9 16.2 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORX95993.1 - 1.6e-36 125.8 0.0 6.6e-19 68.8 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORX95993.1 - 2.3e-31 107.6 8.7 2.8e-23 81.6 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX95993.1 - 2.5e-12 47.2 0.0 5.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORX95993.1 - 8.7e-12 44.8 34.0 1.1e-07 31.3 14.4 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX95993.1 - 2.1e-05 24.5 0.0 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORX95993.1 - 4.5e-05 23.9 0.0 0.051 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ORX95993.1 - 0.00013 21.6 0.1 0.012 15.2 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 ORX95993.1 - 0.00013 21.6 0.4 0.0062 16.2 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORX95993.1 - 0.00016 21.6 0.5 0.34 10.7 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORX95993.1 - 0.0039 17.5 0.0 1.5 9.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain DnaB_C PF03796.15 ORX95993.1 - 0.0042 16.5 0.1 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_18 PF13238.6 ORX95993.1 - 0.0059 17.2 0.0 0.33 11.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORX95993.1 - 0.0085 15.8 0.2 4.7 6.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 ORX95993.1 - 0.011 15.3 0.3 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORX95993.1 - 0.026 14.4 0.1 7.9 6.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 ORX95993.1 - 0.072 13.3 0.2 3.6 7.9 0.0 3.1 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 ORX95993.1 - 0.096 12.8 0.2 8.7 6.5 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORX95993.1 - 0.13 12.4 0.5 4.8 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX95993.1 - 0.18 12.1 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORX95993.1 - 0.2 11.4 0.2 4.6 7.0 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 ORX95993.1 - 0.29 11.4 0.8 2.2 8.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORX95993.1 - 0.42 11.0 1.1 26 5.2 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ORX95993.1 - 0.52 10.8 2.4 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 ORX95994.1 - 1.7e-89 298.8 55.5 2.3e-48 164.4 21.2 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORX95994.1 - 1.1e-36 126.4 0.1 6.6e-19 68.8 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 ORX95994.1 - 3.9e-24 84.4 1.3 2.9e-20 71.9 0.0 3.9 3 1 1 4 4 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORX95994.1 - 1.5e-16 60.4 30.6 5e-10 39.0 11.3 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 ORX95994.1 - 3.3e-12 46.8 0.1 7.8e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 ORX95994.1 - 2.8e-05 24.1 0.1 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORX95994.1 - 2.8e-05 24.6 0.0 0.051 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX95994.1 - 0.00012 21.7 0.5 0.0062 16.2 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORX95994.1 - 0.00013 21.9 0.1 0.34 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORX95994.1 - 0.00068 19.3 0.2 0.012 15.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX95994.1 - 0.0012 19.1 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORX95994.1 - 0.0047 17.5 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX95994.1 - 0.0048 16.6 0.1 3.9 7.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 ORX95994.1 - 0.013 15.1 0.2 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 ORX95994.1 - 0.028 13.8 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NACHT PF05729.12 ORX95994.1 - 0.03 14.2 0.3 8.6 6.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 ORX95994.1 - 0.061 13.7 0.0 4.9 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ORX95994.1 - 0.078 13.2 0.1 3.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORX95994.1 - 0.18 12.0 0.3 4.8 7.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORX95994.1 - 0.2 11.7 0.2 8.7 6.5 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORX95994.1 - 0.24 11.1 0.5 4.6 7.0 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane PF01061.24 ORX95995.1 - 9.7e-84 280.0 46.1 4.8e-48 163.4 18.8 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ORX95995.1 - 7.1e-37 127.0 0.0 6.6e-19 68.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORX95995.1 - 1.9e-30 104.6 10.9 5.6e-23 80.7 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORX95995.1 - 9.9e-13 48.5 0.0 2.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORX95995.1 - 1.3e-11 44.3 37.6 1e-07 31.4 17.9 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORX95995.1 - 1.2e-05 25.3 0.1 0.00017 21.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORX95995.1 - 0.00012 22.5 0.0 0.051 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ORX95995.1 - 0.00015 21.7 0.1 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORX95995.1 - 0.00016 21.4 0.6 0.0062 16.2 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORX95995.1 - 0.00026 20.6 0.1 0.012 15.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 ORX95995.1 - 0.0049 16.2 0.1 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_18 PF13238.6 ORX95995.1 - 0.0079 16.7 0.0 0.33 11.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 ORX95995.1 - 0.0079 16.5 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORX95995.1 - 0.011 15.3 0.2 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORX95995.1 - 0.017 14.9 0.2 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORX95995.1 - 0.019 14.9 0.1 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 ORX95995.1 - 0.073 13.3 0.2 3.6 7.9 0.0 3.1 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORX95995.1 - 0.14 12.3 0.3 4.8 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX95995.1 - 0.21 11.9 0.0 17 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORX95995.1 - 0.21 11.3 0.2 4.6 7.0 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 ORX95995.1 - 0.3 11.5 0.8 25 5.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps26 PF03643.15 ORX95996.1 - 9.3e-128 425.0 5.5 1.1e-127 424.8 5.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 ORX95996.1 - 0.0011 19.4 0.6 0.011 16.2 0.1 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX95996.1 - 0.0019 18.3 1.2 0.15 12.2 0.1 3.0 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_C PF00137.21 ORX95997.1 - 2.3e-26 91.9 32.6 3.8e-15 56.0 10.3 2.9 3 0 0 3 3 3 2 ATP synthase subunit C Amelogenin PF02948.15 ORX95998.1 - 0.19 12.3 0.0 0.32 11.6 0.0 1.2 1 0 0 1 1 1 0 Amelogenin Protoglobin PF11563.8 ORX95999.1 - 3.2e-10 40.1 0.0 3.5e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Protoglobin DUF3723 PF12520.8 ORX95999.1 - 0.013 14.2 0.0 0.015 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) CAP PF00188.26 ORX96000.1 - 9.3e-20 71.7 0.3 1.2e-19 71.4 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family F-box PF00646.33 ORX96001.1 - 0.0054 16.6 2.9 0.011 15.6 1.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORX96001.1 - 0.051 13.5 1.4 0.051 13.5 1.4 2.3 3 0 0 3 3 3 0 F-box-like zf-B_box PF00643.24 ORX96001.1 - 2.7 8.2 13.2 1.9 8.7 0.3 3.4 2 1 1 3 3 3 0 B-box zinc finger HSP70 PF00012.20 ORX96002.1 - 2.4e-258 858.3 9.8 2.7e-258 858.1 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX96002.1 - 2.1e-18 66.3 0.7 2.3e-17 62.8 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Enolase_N PF03952.16 ORX96002.1 - 0.001 19.2 0.6 1.9 8.6 0.1 2.6 2 0 0 2 2 2 2 Enolase, N-terminal domain Hydantoinase_A PF01968.18 ORX96002.1 - 0.0017 17.7 2.1 0.0047 16.2 0.2 2.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.6 ORX96002.1 - 0.028 14.8 4.4 1 9.8 0.3 3.2 3 2 0 3 3 3 0 Cell division protein FtsA Radial_spoke_3 PF06098.11 ORX96002.1 - 0.34 10.2 8.2 0.17 11.1 4.5 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 DUF1779 PF08680.10 ORX96002.1 - 6.8 6.8 10.6 0.082 13.1 1.2 2.4 3 1 0 3 3 3 0 TATA-box binding Ribosomal_L10 PF00466.20 ORX96003.1 - 1.3e-25 89.4 2.6 4.7e-25 87.6 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORX96003.1 - 7.1e-22 77.2 0.1 1.3e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 ORX96003.1 - 1.3e-19 70.6 8.5 1.3e-19 70.5 6.0 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein VEG PF06257.11 ORX96003.1 - 0.035 14.2 0.9 0.23 11.5 0.0 2.5 3 0 0 3 3 3 0 Biofilm formation stimulator VEG NIF PF03031.18 ORX96004.1 - 7.1e-55 185.0 0.2 9.6e-55 184.6 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORX96004.1 - 0.037 14.4 0.1 0.34 11.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ACBP PF00887.19 ORX96005.1 - 2.7e-22 78.8 0.0 5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein PPR PF01535.20 ORX96006.1 - 4.8e-09 35.9 0.3 0.00069 19.7 0.0 4.9 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.6 ORX96006.1 - 1.7e-05 24.9 0.2 0.34 11.1 0.0 4.7 5 0 0 5 5 5 1 PPR repeat family PPR_long PF17177.4 ORX96006.1 - 6.6e-05 22.4 0.3 0.086 12.2 0.0 3.4 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 ORX96006.1 - 0.00013 22.0 0.0 1.3 9.2 0.0 4.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain ATP13 PF12921.7 ORX96006.1 - 0.00038 20.3 0.0 0.034 14.0 0.0 2.8 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_1 PF12854.7 ORX96006.1 - 0.008 15.9 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 1 PPR repeat BTAD PF03704.17 ORX96006.1 - 0.077 13.4 0.8 5.3 7.5 0.1 3.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_16 PF13432.6 ORX96006.1 - 0.52 11.0 2.8 15 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L18 PF17135.4 ORX96007.1 - 3e-97 323.5 2.9 3.3e-97 323.3 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORX96007.1 - 0.0079 16.9 0.1 0.029 15.0 0.1 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-H2C2_2 PF13465.6 ORX96008.1 - 1.6e-10 40.9 9.6 1.4e-06 28.4 1.5 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX96008.1 - 2e-08 34.3 15.5 0.00023 21.4 3.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96008.1 - 6.4e-07 29.7 13.3 0.0045 17.7 2.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX96008.1 - 3.5e-06 26.9 10.1 0.00047 20.1 2.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX96008.1 - 4.9e-06 26.7 5.6 0.00093 19.5 1.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX96008.1 - 7.5e-05 22.9 3.8 0.03 14.6 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORX96008.1 - 0.024 14.5 0.9 0.024 14.5 0.9 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 ORX96008.1 - 0.18 12.2 4.8 0.45 10.9 0.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 ORX96008.1 - 3.3 7.9 8.7 0.65 10.2 1.7 2.1 1 1 1 2 2 2 0 FYVE zinc finger Cnd1 PF12717.7 ORX96009.1 - 8.7e-07 29.1 14.7 0.002 18.2 0.3 4.8 4 3 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 ORX96009.1 - 1.3e-06 28.3 1.5 0.0045 16.8 0.0 4.5 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 ORX96009.1 - 1.9e-06 28.3 3.1 0.0083 16.6 0.1 4.6 4 1 1 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 ORX96009.1 - 2.8e-06 27.5 15.8 0.08 13.1 0.2 6.1 5 2 2 7 7 7 3 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 ORX96009.1 - 8.1e-06 26.2 1.5 1.1 9.7 0.2 5.6 4 3 4 8 8 7 3 HEAT repeats CLASP_N PF12348.8 ORX96009.1 - 1.2e-05 25.0 10.3 0.00014 21.5 0.2 3.8 2 2 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 ORX96009.1 - 1.7e-05 24.6 5.0 7.3 7.1 0.0 7.7 9 0 0 9 9 8 1 HEAT repeat MMS19_N PF14500.6 ORX96009.1 - 0.0013 18.4 10.1 0.48 10.0 0.3 5.0 2 2 1 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 ORX96009.1 - 0.01 16.4 9.1 0.73 10.5 1.2 4.8 4 2 0 4 4 3 0 Rix1 complex component involved in 60S ribosome maturation TFCD_C PF12612.8 ORX96009.1 - 0.024 14.5 9.8 1.6 8.5 0.0 4.0 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal TetR_C_27 PF17935.1 ORX96009.1 - 0.025 14.6 0.2 0.21 11.7 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain VHS PF00790.19 ORX96009.1 - 0.1 12.5 1.3 1 9.2 0.0 3.3 2 1 1 3 3 3 0 VHS domain FGE-sulfatase PF03781.16 ORX96010.1 - 1.2e-29 103.8 4.5 1.6e-29 103.3 4.5 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_31 PF13847.6 ORX96010.1 - 4.4e-10 39.6 0.0 1.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORX96010.1 - 1.5e-09 37.9 0.0 4.4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX96010.1 - 1.8e-07 31.8 0.0 2e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX96010.1 - 2.8e-07 31.1 0.0 0.00098 19.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORX96010.1 - 3.2e-06 27.8 0.0 0.053 14.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain DREV PF05219.12 ORX96010.1 - 3.9e-06 26.1 0.0 0.057 12.5 0.0 2.2 2 0 0 2 2 2 2 DREV methyltransferase DinB_2 PF12867.7 ORX96010.1 - 2.7e-05 24.7 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 DinB superfamily Thr_synth_N PF14821.6 ORX96011.1 - 8.6e-30 102.8 0.0 2e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ORX96011.1 - 5.3e-14 52.3 0.0 2.5e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAD_binding_3 PF01494.19 ORX96012.1 - 1.1e-19 70.9 0.2 1.5e-18 67.2 0.2 2.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORX96012.1 - 0.0014 17.8 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase R3H PF01424.22 ORX96013.1 - 5.3e-05 23.1 3.5 0.0001 22.2 0.3 2.8 2 1 0 2 2 2 1 R3H domain R3H-assoc PF13902.6 ORX96013.1 - 0.00018 21.9 4.0 0.00041 20.8 4.0 1.8 1 1 0 1 1 1 1 R3H-associated N-terminal domain T_hemolysin PF12261.8 ORX96013.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin DUF4734 PF15881.5 ORX96013.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4734) RPN7 PF10602.9 ORX96014.1 - 8.3e-55 185.2 3.3 1.2e-54 184.6 3.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORX96014.1 - 1.9e-15 57.2 0.3 6.8e-15 55.5 0.0 2.1 3 0 0 3 3 3 1 PCI domain TPR_15 PF13429.6 ORX96014.1 - 0.02 14.1 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX96014.1 - 0.024 14.7 0.6 0.099 12.8 0.6 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 ORX96014.1 - 0.031 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family HTH_DeoR PF08220.12 ORX96014.1 - 0.047 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TPR_8 PF13181.6 ORX96014.1 - 0.099 12.9 0.6 0.43 10.9 0.6 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_11 PF08279.12 ORX96014.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain BLOC1_2 PF10046.9 ORX96014.1 - 0.44 10.9 4.6 2 8.7 0.3 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_6 PF13174.6 ORX96014.1 - 0.74 10.6 2.9 0.71 10.6 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN6_N PF18055.1 ORX96015.1 - 4.6e-42 143.1 1.1 4.6e-42 143.1 1.1 2.6 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 ORX96015.1 - 1.3e-20 73.8 2.7 1.2e-19 70.8 0.1 3.3 4 0 0 4 4 4 1 PCI domain RPN6_C_helix PF18503.1 ORX96015.1 - 6.6e-13 48.1 1.4 6.6e-13 48.1 1.4 2.4 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 ORX96015.1 - 0.003 17.8 10.1 2.1 8.7 0.6 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORX96015.1 - 0.05 14.3 1.3 27 5.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX96015.1 - 0.1 12.0 4.5 0.058 12.8 1.4 2.1 2 1 1 3 3 3 0 MalT-like TPR region TPR_19 PF14559.6 ORX96015.1 - 1.7 9.2 8.9 5 7.7 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX96015.1 - 1.8 8.7 6.7 74 3.7 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX96017.1 - 1.4e-10 41.3 2.5 9.3e-08 32.3 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX96017.1 - 6.4e-06 25.9 0.4 0.042 14.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX96017.1 - 0.00018 21.2 0.1 0.93 9.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX96017.1 - 0.0014 18.7 0.9 1.9 8.9 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX96017.1 - 0.0066 15.9 0.4 0.011 15.2 0.4 1.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 ORX96017.1 - 0.0091 16.6 0.8 7.5 7.3 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat YfmQ PF10787.9 ORX96017.1 - 0.01 15.6 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group SHNi-TPR PF10516.9 ORX96017.1 - 0.016 14.6 0.2 0.12 11.8 0.0 2.6 3 0 0 3 3 3 0 SHNi-TPR TPR_19 PF14559.6 ORX96017.1 - 0.022 15.3 0.8 11 6.6 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 ORX96017.1 - 0.025 14.6 0.7 13 5.9 0.0 3.0 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 ORX96017.1 - 0.032 13.9 0.2 5.5 6.8 0.0 3.5 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 ORX96017.1 - 0.061 14.2 0.1 9.2 7.4 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 ORX96017.1 - 0.091 12.5 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Asp PF00026.23 ORX96018.1 - 1.1e-52 179.4 0.0 1.2e-52 179.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX96018.1 - 5e-10 39.9 2.3 1.5e-06 28.6 0.3 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORX96018.1 - 7.2e-05 23.4 0.0 0.0053 17.4 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 ORX96018.1 - 0.00092 19.7 0.0 0.019 15.5 0.0 2.6 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease Chs7 PF12271.8 ORX96039.1 - 1e-101 340.1 18.8 1.2e-101 339.9 18.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Col_cuticle_N PF01484.17 ORX96039.1 - 0.028 14.5 4.1 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF2070 PF09843.9 ORX96039.1 - 3.9 5.7 30.6 34 2.5 30.9 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) YrhC PF14143.6 ORX96039.1 - 4.2 7.5 7.4 0.81 9.8 3.0 2.1 2 0 0 2 2 2 0 YrhC-like protein SH3_1 PF00018.28 ORX96040.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX96040.1 - 4.6e-05 23.2 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Insulin_TMD PF17870.1 ORX96040.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Lipase_GDSL PF00657.22 ORX96042.1 - 5.3e-06 26.5 0.0 6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase bPH_3 PF14470.6 ORX96043.1 - 0.1 13.0 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial PH domain Cullin PF00888.22 ORX96044.1 - 8.1e-201 668.8 22.3 1.1e-200 668.5 22.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORX96044.1 - 2.2e-22 78.9 1.3 6e-22 77.5 1.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain NAD_kinase PF01513.21 ORX96045.1 - 6.8e-66 222.4 0.0 9.1e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RILP PF11461.8 ORX96046.1 - 0.048 13.9 0.8 3.8 7.8 0.1 2.6 1 1 1 2 2 2 0 Rab interacting lysosomal protein SLATT_5 PF18160.1 ORX96046.1 - 0.054 12.8 0.4 0.2 11.0 0.4 2.0 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 TMF_TATA_bd PF12325.8 ORX96046.1 - 0.3 11.3 3.0 0.62 10.3 3.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1348 PF07080.11 ORX96047.1 - 8.9e-65 216.5 8.4 1e-64 216.3 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ORX96047.1 - 1.7e-09 38.3 2.1 2e-09 38.0 2.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ORX96047.1 - 0.00017 21.9 0.2 0.00023 21.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4224 PF13986.6 ORX96047.1 - 0.014 15.3 0.2 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) SnoaL PF07366.12 ORX96047.1 - 0.045 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Tetraspanin PF00335.20 ORX96048.1 - 3.7e-14 53.0 11.8 4.5e-14 52.7 11.8 1.0 1 0 0 1 1 1 1 Tetraspanin family GCP_C_terminal PF04130.13 ORX96049.1 - 3.8e-61 207.2 8.4 5.1e-61 206.8 8.4 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORX96049.1 - 3.2e-22 79.6 0.7 1.7e-13 50.9 0.0 3.2 2 1 1 3 3 3 2 Gamma tubulin complex component N-terminal Ig_5 PF16681.5 ORX96049.1 - 0.1 13.0 0.2 0.22 11.9 0.2 1.5 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain MYEOV2 PF15004.6 ORX96049.1 - 0.12 12.8 0.3 27 5.3 0.0 2.5 2 0 0 2 2 2 0 Myeloma-overexpressed-like V-SNARE_C PF12352.8 ORX96050.1 - 0.0002 21.6 12.4 0.0026 18.0 1.6 2.5 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus BMP2K_C PF15282.6 ORX96050.1 - 0.036 13.9 5.0 0.056 13.3 5.0 1.4 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus DUF4901 PF16244.5 ORX96050.1 - 0.066 12.6 0.4 0.066 12.6 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4901) XhlA PF10779.9 ORX96050.1 - 0.63 10.3 8.5 0.19 11.9 1.4 3.0 2 2 1 3 3 3 0 Haemolysin XhlA DUF1359 PF07097.11 ORX96050.1 - 0.96 9.7 6.0 0.21 11.8 1.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) Pro_isomerase PF00160.21 ORX96051.1 - 2.8e-39 134.9 0.0 3.4e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 ORX96052.1 - 3e-37 127.2 0.2 3e-37 127.2 0.2 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 ORX96052.1 - 2.4e-10 40.9 1.1 3.4e-10 40.4 0.1 1.9 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 ORX96052.1 - 4.6e-07 29.8 7.6 7.2e-07 29.1 7.6 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PAP2 PF01569.21 ORX96053.1 - 9.3e-15 54.6 5.7 9.3e-15 54.6 5.7 2.8 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 ORX96053.1 - 0.0059 16.3 12.0 0.91 9.2 9.1 3.4 2 1 0 2 2 2 2 PAP2 superfamily DUF1440 PF07274.12 ORX96053.1 - 0.014 15.7 1.3 0.014 15.7 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) YqhR PF11085.8 ORX96053.1 - 0.5 10.3 8.8 0.47 10.4 5.1 2.3 2 0 0 2 2 2 0 Conserved membrane protein YqhR PTPS PF01242.19 ORX96054.1 - 1.2e-34 118.9 0.5 1.4e-34 118.7 0.5 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF3969 PF13108.6 ORX96054.1 - 0.034 14.2 0.6 0.046 13.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Sulfate_transp PF00916.20 ORX96055.1 - 8.9e-90 301.2 20.9 8.9e-90 301.2 20.9 1.6 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 ORX96055.1 - 1.4e-19 69.9 0.0 2.6e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORX96055.1 - 0.00044 20.5 0.0 0.0015 18.9 0.0 2.0 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 ORX96055.1 - 0.006 17.0 5.9 0.006 17.0 5.9 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily DEAD_2 PF06733.15 ORX96056.1 - 1.4e-55 187.7 0.2 2.5e-55 186.8 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 ORX96056.1 - 6.5e-50 169.5 2.7 2.3e-44 151.4 0.7 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 ORX96056.1 - 1.2e-46 159.1 0.0 3.3e-46 157.6 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 ORX96056.1 - 2.5e-06 27.6 0.0 0.00028 20.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORX96056.1 - 0.0011 17.7 0.0 0.0043 15.8 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 ORX96056.1 - 0.004 16.9 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF5550 PF17704.1 ORX96056.1 - 0.01 16.0 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5550) Exog_C PF18026.1 ORX96056.1 - 0.066 13.3 0.3 7.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain YtxC PF08812.11 ORX96056.1 - 0.089 12.4 0.5 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 YtxC-like family AAA_22 PF13401.6 ORX96056.1 - 0.091 13.0 0.1 10 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.23 ORX96057.1 - 2.4e-29 101.8 1.8 4.5e-29 101.0 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORX96057.1 - 3.8e-17 62.1 5.0 3.8e-17 62.1 5.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 ORX96057.1 - 0.013 14.9 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ABC_membrane PF00664.23 ORX96059.1 - 1.4e-132 441.5 34.3 1.3e-66 225.1 15.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX96059.1 - 5.9e-66 221.2 0.1 1.6e-35 122.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX96059.1 - 1e-13 51.3 10.0 1.3e-05 24.7 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORX96059.1 - 8.9e-08 32.7 1.6 0.0045 17.4 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORX96059.1 - 1.7e-07 30.9 0.4 0.017 14.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORX96059.1 - 2.5e-07 29.9 1.2 0.00055 18.8 0.1 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class G-alpha PF00503.20 ORX96059.1 - 1.5e-06 27.6 0.1 0.03 13.5 0.0 2.5 3 0 0 3 3 2 2 G-protein alpha subunit DUF87 PF01935.17 ORX96059.1 - 2.2e-06 27.9 0.1 0.011 15.8 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 ORX96059.1 - 2.9e-06 27.3 0.0 0.0068 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORX96059.1 - 5.1e-06 25.9 0.0 0.019 14.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 ORX96059.1 - 7.2e-06 25.4 0.0 0.041 13.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 ORX96059.1 - 1.1e-05 25.4 0.4 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORX96059.1 - 1.4e-05 25.4 1.1 0.12 12.7 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORX96059.1 - 4.1e-05 23.2 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORX96059.1 - 0.00011 21.7 0.0 0.55 9.5 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family SbcCD_C PF13558.6 ORX96059.1 - 0.00012 22.2 2.8 0.71 10.1 0.3 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ORX96059.1 - 0.00016 21.4 0.0 2.2 7.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 ORX96059.1 - 0.00033 21.1 0.1 6 7.3 0.0 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX96059.1 - 0.0004 20.4 0.0 1.5 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORX96059.1 - 0.00079 19.2 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX96059.1 - 0.0031 17.7 0.1 4.1 7.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ORX96059.1 - 0.0041 17.3 0.0 4.2 7.6 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 ORX96059.1 - 0.0056 16.4 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 ORX96059.1 - 0.0082 16.0 0.3 4.6 7.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 ORX96059.1 - 0.0099 15.8 0.1 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 ORX96059.1 - 0.011 16.2 0.0 10 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ORX96059.1 - 0.014 15.2 0.3 19 5.0 0.0 3.5 3 1 0 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 ORX96059.1 - 0.017 14.9 0.1 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 ORX96059.1 - 0.02 14.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 ORX96059.1 - 0.03 14.6 0.1 11 6.2 0.1 3.0 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 ORX96059.1 - 0.04 14.0 0.3 12 6.0 0.1 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 ORX96059.1 - 0.041 13.8 0.0 9.9 6.0 0.0 2.9 3 0 0 3 3 3 0 NTPase FumaraseC_C PF10415.9 ORX96059.1 - 0.054 13.9 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Fumarase C C-terminus NDUF_B12 PF08122.12 ORX96059.1 - 0.064 13.3 3.1 0.54 10.3 0.1 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family NACHT PF05729.12 ORX96059.1 - 0.1 12.5 0.5 12 5.8 0.0 2.9 3 0 0 3 3 2 0 NACHT domain NB-ARC PF00931.22 ORX96059.1 - 0.11 11.7 0.8 6.8 5.8 0.3 2.7 2 1 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 ORX96059.1 - 0.18 12.3 0.2 25 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain CobD_Cbib PF03186.13 ORX96059.1 - 7.5 5.7 7.7 4.9 6.3 2.8 2.8 2 1 0 2 2 2 0 CobD/Cbib protein DUF4190 PF13828.6 ORX96086.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) DUF5373 PF17343.2 ORX96086.1 - 1.5 8.6 8.9 4.2 7.2 8.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Astacin PF01400.24 ORX96087.1 - 0.064 12.9 0.4 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) GPI-anchored PF10342.9 ORX96088.1 - 0.012 16.4 0.1 0.068 13.9 0.1 2.1 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mpv17_PMP22 PF04117.12 ORX96089.1 - 1e-09 38.5 2.0 1e-09 38.5 2.0 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family EI24 PF07264.11 ORX96089.1 - 0.12 12.6 3.6 0.19 12.0 3.6 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Abhydrolase_1 PF00561.20 ORX96090.1 - 2.6e-16 60.0 0.0 6.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX96090.1 - 1.4e-11 44.1 0.0 4.2e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX96090.1 - 1.1e-08 36.0 0.0 1.4e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX96090.1 - 0.00036 20.1 0.2 0.15 11.5 0.0 2.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 ORX96090.1 - 0.0012 18.6 0.0 0.0021 17.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 ORX96090.1 - 0.015 14.9 0.0 0.058 13.0 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ORX96090.1 - 0.02 14.7 0.0 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase HAD PF12710.7 ORX96090.1 - 0.12 12.7 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Esterase PF00756.20 ORX96090.1 - 0.14 11.7 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 ORX96090.1 - 0.17 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein SOBP PF15279.6 ORX96091.1 - 5.2 7.6 14.6 6.7 7.2 14.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein MFS_1 PF07690.16 ORX96092.1 - 4e-66 223.3 61.0 4.9e-52 177.0 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX96092.1 - 8.1e-12 44.7 20.9 8.8e-11 41.3 20.8 2.7 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 ORX96092.1 - 1.4e-09 37.0 21.8 2.5e-05 22.9 9.1 2.3 1 1 1 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 ORX96092.1 - 0.057 11.7 22.1 0.012 13.9 1.8 3.5 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 ORX96092.1 - 0.14 12.0 7.2 0.48 10.3 1.3 3.2 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 WRKY PF03106.15 ORX96093.1 - 1.7e-07 31.4 0.6 2.8e-07 30.7 0.6 1.3 1 0 0 1 1 1 1 WRKY DNA -binding domain Methyltransf_31 PF13847.6 ORX96093.1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Surp PF01805.20 ORX96094.1 - 8.3e-30 102.6 0.7 4.3e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 ORX96094.1 - 7.5e-17 61.9 4.1 7.5e-17 61.9 4.1 1.7 2 0 0 2 2 2 1 Alternative splicing regulator Cmc1 PF08583.10 ORX96096.1 - 5.1e-05 23.2 1.5 7.9e-05 22.6 1.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 ORX96096.1 - 0.12 12.4 4.4 1.3 9.1 0.9 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 ORX96096.1 - 0.15 12.4 6.4 0.1 13.0 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Pet191_N PF10203.9 ORX96096.1 - 0.22 11.9 2.1 0.59 10.5 2.1 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Tyrosinase PF00264.20 ORX96097.1 - 7.8e-34 117.9 13.6 2e-32 113.3 11.1 2.6 2 1 0 2 2 2 1 Common central domain of tyrosinase PPO1_DWL PF12142.8 ORX96097.1 - 0.098 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Polyphenol oxidase middle domain MFS_1 PF07690.16 ORX96098.1 - 4.4e-37 127.8 30.0 5.9e-37 127.4 30.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 ORX96099.1 - 1.2e-13 50.6 9.0 9.8e-07 28.9 1.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX96099.1 - 1e-10 41.5 11.3 1.1e-06 28.7 0.5 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX96099.1 - 9.3e-10 38.5 8.1 6.4e-05 23.5 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96099.1 - 2.8e-07 30.7 6.8 9.1e-06 25.8 0.8 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX96099.1 - 5.1e-06 26.3 7.6 0.0024 17.8 0.6 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORX96099.1 - 6.3e-06 26.4 0.9 6.3e-06 26.4 0.9 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORX96099.1 - 0.00017 22.0 4.9 0.016 15.7 0.2 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 ORX96099.1 - 0.0006 19.7 1.2 0.0072 16.2 0.6 2.1 1 1 1 2 2 2 1 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 ORX96099.1 - 0.016 15.0 9.2 0.044 13.6 0.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 ORX96099.1 - 0.025 14.9 3.7 0.81 10.1 0.7 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORX96099.1 - 0.036 14.1 6.8 0.73 9.9 1.0 2.2 1 1 1 2 2 2 0 BED zinc finger Spt46 PF17734.1 ORX96099.1 - 0.036 13.9 2.0 0.043 13.6 1.6 1.4 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 zf-C2H2_aberr PF17017.5 ORX96099.1 - 0.047 13.8 1.5 0.07 13.3 0.7 1.5 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 ORX96099.1 - 0.057 13.3 0.8 0.44 10.4 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 ORX96099.1 - 0.15 11.8 4.4 2.8 7.8 1.2 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_C2HC_14 PF18574.1 ORX96099.1 - 0.29 10.9 5.7 0.27 11.1 0.6 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain zf-C2H2_12 PF18658.1 ORX96099.1 - 0.72 9.5 3.7 4.1 7.0 0.6 2.1 1 1 1 2 2 2 0 Zinc-finger C2H2-type Radical_SAM PF04055.21 ORX96100.1 - 2.2e-17 63.9 0.0 6.2e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.16 ORX96100.1 - 0.00047 20.2 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 HemN C-terminal domain Fer4_12 PF13353.6 ORX96100.1 - 0.0039 17.5 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORX96100.1 - 0.034 14.3 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain FHA PF00498.26 ORX96101.1 - 6.7e-16 58.4 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORX96101.1 - 0.0021 18.3 0.0 0.0057 17.0 0.0 1.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Taxilin PF09728.9 ORX96102.1 - 0.0011 18.2 12.1 0.0011 18.2 12.1 2.3 1 1 1 2 2 2 1 Myosin-like coiled-coil protein YabA PF06156.13 ORX96102.1 - 0.0027 18.3 21.4 0.008 16.8 7.2 3.7 1 1 2 3 3 3 2 Initiation control protein YabA SCAB-ABD PF16711.5 ORX96102.1 - 0.11 12.5 3.6 0.099 12.6 1.0 2.3 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein TSC22 PF01166.18 ORX96102.1 - 0.19 12.0 15.5 0.37 11.1 1.5 4.1 1 1 4 5 5 5 0 TSC-22/dip/bun family Matrilin_ccoil PF10393.9 ORX96102.1 - 0.27 11.1 9.5 16 5.4 0.0 4.0 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ORF6C PF10552.9 ORX96102.1 - 0.34 11.0 11.4 0.14 12.2 4.7 2.3 1 1 1 2 2 2 0 ORF6C domain DUF4636 PF15468.6 ORX96102.1 - 0.35 10.5 10.4 0.36 10.5 6.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4636) Rootletin PF15035.6 ORX96102.1 - 0.45 10.5 23.3 0.92 9.5 23.3 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion JAKMIP_CC3 PF16034.5 ORX96102.1 - 0.77 9.7 25.6 1.6 8.6 22.2 2.5 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF4763 PF15960.5 ORX96102.1 - 1 8.6 23.0 0.58 9.4 9.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) UPF0184 PF03670.13 ORX96102.1 - 1.5 9.3 9.2 0.12 12.7 2.1 2.8 2 1 2 4 4 3 0 Uncharacterised protein family (UPF0184) Uso1_p115_C PF04871.13 ORX96102.1 - 2.7 8.4 23.7 0.3 11.5 6.7 3.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rota_VP2 PF05087.12 ORX96102.1 - 2.9 5.9 11.6 3.7 5.6 11.6 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein GLE1 PF07817.13 ORX96102.1 - 4.4 6.4 9.5 0.27 10.4 3.7 1.8 2 0 0 2 2 2 0 GLE1-like protein PRKG1_interact PF15898.5 ORX96102.1 - 5.4 8.0 29.4 3.9 8.4 9.6 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Exo_endo_phos PF03372.23 ORX96103.1 - 1.7e-15 57.2 0.8 3.3e-15 56.2 0.8 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Drc1-Sld2 PF11719.8 ORX96103.1 - 0.051 13.1 4.7 0.071 12.6 4.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DIOX_N PF14226.6 ORX96104.1 - 3e-35 121.5 0.0 4.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORX96104.1 - 4.4e-21 75.3 0.0 1.5e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Phage_endo_I PF05367.11 ORX96104.1 - 0.015 14.9 0.0 0.081 12.5 0.0 2.0 2 0 0 2 2 2 0 Phage endonuclease I PORR PF11955.8 ORX96104.1 - 0.033 13.2 0.6 0.13 11.1 0.0 2.0 2 1 0 2 2 2 0 Plant organelle RNA recognition domain PWI PF01480.17 ORX96105.1 - 4e-13 49.5 0.1 9.4e-13 48.3 0.0 1.7 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 ORX96105.1 - 8.7e-10 38.3 0.0 2.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UreE_C PF05194.12 ORX96105.1 - 0.029 14.9 1.2 0.1 13.1 1.2 1.9 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Pyr_redox_2 PF07992.14 ORX96106.1 - 3.3e-55 187.4 0.0 3.8e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORX96106.1 - 1.6e-18 67.0 0.3 3.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX96106.1 - 3.2e-18 66.0 0.5 8.2e-16 58.3 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX96106.1 - 4.9e-06 26.1 0.2 0.00027 20.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORX96106.1 - 0.00016 21.0 0.1 0.00054 19.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ORX96106.1 - 0.00042 20.5 0.2 0.018 15.2 0.1 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX96106.1 - 0.0008 18.6 1.5 0.0065 15.6 0.4 2.8 4 0 0 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 ORX96106.1 - 0.001 18.3 0.1 0.43 9.7 0.0 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 ORX96106.1 - 0.0038 16.4 2.4 0.04 13.0 1.2 2.6 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 ORX96106.1 - 0.0048 15.6 1.2 0.031 13.0 0.8 2.3 2 1 1 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 ORX96106.1 - 0.0049 17.3 0.1 0.19 12.2 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 ORX96106.1 - 0.0074 15.9 0.4 1.2 8.7 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX96106.1 - 0.044 13.1 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORX96106.1 - 0.065 12.5 0.4 0.25 10.5 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 ORX96106.1 - 0.21 10.4 1.7 0.73 8.6 0.7 2.2 2 1 1 3 3 3 0 Tryptophan halogenase Cation_efflux PF01545.21 ORX96108.1 - 3.5e-23 82.4 10.5 4.2e-23 82.1 10.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORX96108.1 - 7.9e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PhoLip_ATPase_C PF16212.5 ORX96108.1 - 0.0029 17.4 3.9 0.0047 16.7 3.9 1.3 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal SecIII_SopE_N PF05364.14 ORX96109.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus E1-E2_ATPase PF00122.20 ORX96109.1 - 1.8 8.1 4.7 4.4 6.8 4.7 1.6 1 0 0 1 1 1 0 E1-E2 ATPase RGS PF00615.19 ORX96110.1 - 4e-16 59.4 5.7 2.8e-15 56.6 0.1 3.2 3 0 0 3 3 3 2 Regulator of G protein signaling domain CdiI_2 PF18593.1 ORX96110.1 - 0.02 15.5 0.6 0.13 12.9 0.1 2.7 3 0 0 3 3 3 0 CdiI immunity protein Ald_Xan_dh_C2 PF02738.18 ORX96111.1 - 1.4e-202 674.0 0.0 2e-202 673.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORX96111.1 - 3.7e-51 173.2 0.0 7.5e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 ORX96111.1 - 3.1e-33 114.4 0.4 9.9e-33 112.8 0.1 2.1 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ORX96111.1 - 5.8e-32 109.5 0.0 1.2e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 ORX96111.1 - 5.8e-27 93.9 0.0 4.9e-25 87.7 0.0 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 ORX96111.1 - 1.5e-10 40.9 0.1 1.5e-10 40.9 0.1 2.6 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DOCK_N PF16172.5 ORX96112.1 - 1.4e-86 290.8 0.0 2.8e-86 289.8 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 ORX96112.1 - 1.5e-82 278.0 10.1 5.2e-82 276.2 10.1 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 ORX96112.1 - 2.4e-51 174.3 0.7 6.4e-51 172.9 0.7 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Imm43 PF15570.6 ORX96112.1 - 0.028 14.4 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 43 Uteroglobin PF01099.17 ORX96112.1 - 0.06 13.7 0.2 21 5.6 0.0 3.4 3 0 0 3 3 3 0 Uteroglobin family PI3K_C2 PF00792.24 ORX96112.1 - 0.092 12.7 0.1 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 SH3_2 PF07653.17 ORX96112.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain G-alpha PF00503.20 ORX96113.1 - 3.2e-111 371.9 0.7 3.8e-111 371.7 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX96113.1 - 4.4e-15 55.6 0.3 1.3e-09 37.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX96113.1 - 9e-06 25.2 0.1 0.055 12.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORX96113.1 - 0.0011 19.1 0.2 0.46 10.7 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORX96113.1 - 0.04 14.0 0.1 8.8 6.4 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX96113.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMP_C2CD2L PF18696.1 ORX96113.1 - 0.12 12.2 0.2 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain tRNA-synt_2d PF01409.20 ORX96114.1 - 1.5e-49 168.7 0.1 2.3e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 ORX96114.1 - 4.7e-18 65.4 0.1 1.8e-17 63.5 0.1 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 ORX96114.1 - 0.0069 15.5 0.0 1.2 8.2 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Glycos_transf_2 PF00535.26 ORX96115.1 - 4.1e-31 108.1 0.0 5.4e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORX96115.1 - 9.6e-09 35.5 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORX96115.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ORX96115.1 - 0.037 14.5 0.0 0.09 13.3 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Sulfatase PF00884.23 ORX96115.1 - 0.25 10.7 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Sulfatase Cyanate_lyase PF02560.14 ORX96116.1 - 3.7e-34 116.4 0.0 5.7e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 ORX96116.1 - 0.0028 18.0 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ORX96116.1 - 0.0096 16.0 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HP0268 PF18618.1 ORX96116.1 - 0.05 14.0 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 HP0268 Homeodomain PF00046.29 ORX96116.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain EF-hand_7 PF13499.6 ORX96117.1 - 4.5e-06 27.0 0.8 0.0001 22.7 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 ORX96117.1 - 5.6e-05 22.4 3.1 9.8e-05 21.7 0.3 2.9 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 ORX96117.1 - 0.00023 20.5 0.2 0.0077 15.7 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 ORX96117.1 - 0.00092 19.0 0.7 0.017 15.0 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 ORX96117.1 - 0.022 14.6 0.1 0.084 12.7 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair DUF948 PF06103.11 ORX96117.1 - 0.12 12.7 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NuiA PF07924.11 ORX96117.1 - 0.2 12.1 3.1 0.37 11.2 0.6 2.4 2 1 1 3 3 3 0 Nuclease A inhibitor-like protein EF-hand_4 PF12763.7 ORX96117.1 - 0.25 11.3 1.2 10 6.1 0.1 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand CBS PF00571.28 ORX96127.1 - 1.4e-18 67.0 1.1 4.5e-07 30.2 0.0 4.8 4 1 0 4 4 4 4 CBS domain DUF4838 PF16126.5 ORX96127.1 - 0.00067 19.1 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) AdoMet_MTase PF07757.13 ORX96128.1 - 2.6e-37 127.6 0.1 3.9e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 ORX96128.1 - 0.00086 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 ORX96128.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORX96128.1 - 0.0016 18.4 0.3 0.017 15.1 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX96128.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX96128.1 - 0.048 14.4 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORX96128.1 - 0.052 14.3 0.0 0.09 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORX96128.1 - 0.064 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pex2_Pex12 PF04757.14 ORX96129.1 - 7.5e-35 120.6 4.8 9.7e-35 120.2 4.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 ORX96129.1 - 1.9e-05 24.4 5.1 4.3e-05 23.3 5.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORX96129.1 - 0.00032 20.8 5.3 0.00078 19.6 5.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORX96129.1 - 0.003 17.4 7.9 0.016 15.0 7.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX96129.1 - 0.0064 16.8 7.6 0.012 15.9 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORX96129.1 - 0.0068 16.3 7.6 0.013 15.5 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_ME53 PF06061.11 ORX96129.1 - 0.011 15.0 2.1 0.019 14.2 2.1 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 zf-RING_UBOX PF13445.6 ORX96129.1 - 0.011 15.7 5.7 0.024 14.7 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 ORX96129.1 - 0.013 15.3 6.4 0.023 14.6 6.4 1.4 1 0 0 1 1 1 0 PHD-finger DUF2180 PF09947.9 ORX96129.1 - 0.034 14.1 1.8 0.056 13.4 0.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-rbx1 PF12678.7 ORX96129.1 - 0.13 12.6 4.4 0.25 11.7 4.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX96129.1 - 0.2 11.7 1.4 0.39 10.8 1.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 ORX96129.1 - 0.53 10.4 4.6 1.1 9.3 4.7 1.6 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 ORX96129.1 - 2 8.3 7.0 0.27 11.1 1.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Tyr_Deacylase PF02580.16 ORX96130.1 - 2.2e-53 180.6 0.0 2.7e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase AA_kinase PF00696.28 ORX96131.1 - 5.1e-38 131.0 0.1 7.8e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 ORX96131.1 - 1.7e-10 40.5 0.7 2.7e-05 23.9 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 ORX96131.1 - 5.2e-10 39.0 3.3 2.9e-07 30.2 0.4 2.5 2 0 0 2 2 2 2 ACT domain MFS_5 PF05631.14 ORX96132.1 - 4.8e-82 275.7 9.4 7e-82 275.2 9.4 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ORX96132.1 - 1.1e-18 67.3 34.6 1.1e-18 67.3 34.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Mpv17_PMP22 PF04117.12 ORX96132.1 - 0.15 12.3 2.3 0.49 10.7 1.0 2.6 2 1 0 2 2 2 0 Mpv17 / PMP22 family MmgE_PrpD PF03972.14 ORX96133.1 - 0.24 9.9 1.3 0.41 9.1 0.2 1.7 2 0 0 2 2 2 0 MmgE/PrpD family FYRC PF05965.14 ORX96134.1 - 0.0004 20.5 0.1 0.0016 18.6 0.1 1.9 1 1 0 1 1 1 1 F/Y rich C-terminus WD40 PF00400.32 ORX96135.1 - 2.9e-05 24.7 5.8 0.0013 19.5 0.1 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX96135.1 - 0.0057 16.9 0.0 1 9.7 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 ORX96135.1 - 0.027 14.2 0.2 0.72 9.5 0.0 2.4 3 0 0 3 3 3 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 ORX96135.1 - 0.059 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 ORX96135.1 - 0.11 11.6 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region VID27 PF08553.10 ORX96135.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Pkinase PF00069.25 ORX96136.1 - 2.9e-72 243.2 0.0 3.6e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96136.1 - 1.6e-36 125.9 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX96136.1 - 3.9e-05 23.1 0.0 0.00056 19.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORX96136.1 - 0.013 14.5 0.0 0.027 13.4 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Laminin_G_1 PF00054.23 ORX96136.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain ANAPC_CDC26 PF10471.9 ORX96136.1 - 0.19 12.6 2.4 0.58 11.0 2.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Pkinase_fungal PF17667.1 ORX96136.1 - 0.24 10.1 0.1 0.24 10.1 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF4588 PF15251.6 ORX96137.1 - 4.8e-08 33.1 1.3 8.2e-08 32.3 1.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.13 ORX96137.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Hairy Orange SH3BGR PF04908.15 ORX96139.1 - 4.9e-11 42.7 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 ORX96139.1 - 2.8e-05 24.2 0.2 0.00027 21.1 0.0 2.7 3 0 0 3 3 3 1 Glutaredoxin Dopey_N PF04118.14 ORX96139.1 - 0.016 14.4 5.3 2.1 7.4 0.2 3.7 3 1 1 4 4 4 0 Dopey, N-terminal DUF1981 PF09324.10 ORX96139.1 - 0.87 9.5 3.4 5.5 6.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Trehalase PF01204.18 ORX96141.1 - 1.4e-132 443.2 10.7 1.7e-131 439.6 10.7 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 ORX96141.1 - 4.1e-06 26.0 3.1 4.4e-05 22.6 3.1 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Ribonuc_2-5A PF06479.12 ORX96141.1 - 0.31 11.2 1.7 0.55 10.4 0.3 2.1 2 0 0 2 2 2 0 Ribonuclease 2-5A PPR_2 PF13041.6 ORX96142.1 - 4.5e-18 65.2 1.1 1e-07 32.0 0.4 5.0 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.20 ORX96142.1 - 8.2e-16 57.1 2.4 0.0075 16.4 0.1 6.3 6 0 0 6 6 6 5 PPR repeat PPR_3 PF13812.6 ORX96142.1 - 1e-10 41.5 1.2 5.3e-05 23.2 0.1 4.2 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX96142.1 - 3.4e-06 26.6 0.0 0.0012 18.2 0.0 2.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORX96142.1 - 3.8e-06 26.5 1.5 0.17 11.6 0.1 3.9 5 0 0 5 5 5 2 PPR repeat AA_kinase PF00696.28 ORX96143.1 - 3.4e-39 134.9 0.0 7.3e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 ORX96143.1 - 1.2e-11 44.2 2.5 5.6e-08 32.5 0.3 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 ORX96143.1 - 1.6e-09 37.3 0.3 7.8e-06 25.6 0.1 2.6 2 0 0 2 2 2 2 ACT domain bZIP_1 PF00170.21 ORX96144.1 - 1.3e-11 44.4 8.9 2.1e-11 43.7 8.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX96144.1 - 6e-08 32.7 5.3 6e-08 32.7 5.3 1.8 1 1 1 2 2 2 1 Basic region leucine zipper HMMR_N PF15905.5 ORX96144.1 - 6.8e-05 22.5 1.6 9.1e-05 22.1 1.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 ORX96144.1 - 0.00019 22.0 0.7 0.00038 21.0 0.3 1.7 1 1 1 2 2 1 1 Initiation control protein YabA bZIP_Maf PF03131.17 ORX96144.1 - 0.00021 21.7 5.4 0.00034 21.1 5.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor SOGA PF11365.8 ORX96144.1 - 0.0022 19.1 2.1 0.0092 17.1 0.0 2.7 3 0 0 3 3 3 1 Protein SOGA Prefoldin_2 PF01920.20 ORX96144.1 - 0.0023 17.9 1.7 0.0049 16.8 1.7 1.6 1 0 0 1 1 1 1 Prefoldin subunit ERM PF00769.19 ORX96144.1 - 0.0049 16.7 1.0 0.0067 16.3 1.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF812 PF05667.11 ORX96144.1 - 0.0065 15.4 0.9 0.0071 15.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 ORX96144.1 - 0.0082 16.4 1.7 0.0082 16.4 1.7 1.8 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ORX96144.1 - 0.012 16.1 1.0 0.018 15.5 1.0 1.3 1 0 0 1 1 1 0 Fez1 DUF641 PF04859.12 ORX96144.1 - 0.022 15.1 4.0 0.082 13.2 3.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.6 ORX96144.1 - 0.027 14.2 2.4 0.043 13.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2205 PF10224.9 ORX96144.1 - 0.034 14.1 4.8 0.049 13.6 1.0 2.3 1 1 1 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 ORX96144.1 - 0.039 12.8 2.7 0.065 12.1 2.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.15 ORX96144.1 - 0.041 14.0 0.9 0.096 12.8 0.9 1.5 1 0 0 1 1 1 0 RasGAP C-terminus DUF1319 PF07028.11 ORX96144.1 - 0.048 13.9 4.8 0.72 10.1 2.2 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF1319) APG6_N PF17675.1 ORX96144.1 - 0.06 13.9 6.4 0.19 12.2 6.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Phlebovirus_NSM PF07246.11 ORX96144.1 - 0.064 12.6 0.6 0.088 12.2 0.6 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CC2-LZ PF16516.5 ORX96144.1 - 0.077 13.4 2.6 0.13 12.7 2.6 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ZapB PF06005.12 ORX96144.1 - 0.094 13.2 0.3 0.094 13.2 0.3 1.8 2 0 0 2 2 1 0 Cell division protein ZapB FlaC_arch PF05377.11 ORX96144.1 - 0.11 12.9 2.7 0.15 12.5 0.9 2.2 2 1 0 2 2 1 0 Flagella accessory protein C (FlaC) RTBV_P46 PF06216.11 ORX96144.1 - 0.11 11.3 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein ADIP PF11559.8 ORX96144.1 - 0.13 12.4 6.3 1 9.4 6.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 ORX96144.1 - 0.14 12.2 4.4 0.34 10.9 4.4 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_TACC PF12709.7 ORX96144.1 - 0.14 12.6 1.6 0.32 11.4 1.5 1.7 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins UPF0242 PF06785.11 ORX96144.1 - 0.14 12.2 7.4 0.34 11.0 7.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 ORX96144.1 - 0.29 9.6 6.5 0.37 9.3 6.5 1.1 1 0 0 1 1 1 0 Macoilin family Chibby PF14645.6 ORX96144.1 - 0.31 11.4 3.7 0.34 11.3 2.3 1.7 2 0 0 2 2 1 0 Chibby family TSC22 PF01166.18 ORX96144.1 - 0.45 10.9 2.5 1.1 9.6 0.5 2.4 2 1 0 2 2 1 0 TSC-22/dip/bun family HIP1_clath_bdg PF16515.5 ORX96144.1 - 0.47 11.1 6.3 1.2 9.8 5.6 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 ORX96144.1 - 0.67 9.8 4.3 0.31 10.8 0.8 2.0 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 ORX96144.1 - 1.1 9.4 3.7 0.83 9.8 0.9 2.3 2 1 0 2 2 2 0 Swi5 TMF_DNA_bd PF12329.8 ORX96144.1 - 1.4 9.0 7.6 1.1 9.3 2.4 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 ORX96144.1 - 1.8 8.8 10.6 4.3 7.5 10.6 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 ORX96144.1 - 1.8 9.0 5.7 1.2 9.6 1.4 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region polyprenyl_synt PF00348.17 ORX96145.1 - 2.7e-63 213.4 0.0 3.4e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3421 PF11901.8 ORX96146.1 - 1.2e-38 131.6 3.2 1.1e-20 73.7 1.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DUF2685 PF10886.8 ORX96146.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) ChAPs PF09295.10 ORX96147.1 - 1.2e-148 495.4 0.0 9e-147 489.2 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 ORX96147.1 - 7.5e-05 23.2 0.1 0.75 10.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORX96147.1 - 0.00014 21.7 2.9 0.064 13.4 0.8 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX96147.1 - 0.00044 20.8 0.1 11 7.1 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX96147.1 - 0.0012 18.9 1.0 0.7 10.3 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat RILP PF11461.8 ORX96147.1 - 0.05 13.8 0.1 1.6 9.1 0.0 3.1 2 0 0 2 2 2 0 Rab interacting lysosomal protein TPR_7 PF13176.6 ORX96147.1 - 0.055 13.5 0.6 76 3.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX96147.1 - 0.057 13.7 1.5 0.34 11.2 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MFS_1 PF07690.16 ORX96148.1 - 7.9e-26 90.8 65.2 6.4e-25 87.8 51.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORX96148.1 - 1.9 7.0 33.9 0.02 13.5 19.4 2.2 1 1 0 2 2 2 0 MFS/sugar transport protein Peptidase_S41 PF03572.18 ORX96149.1 - 8.5e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 zf-C2H2_2 PF12756.7 ORX96150.1 - 1.2e-09 38.4 5.0 1.6e-05 25.1 1.0 2.2 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORX96150.1 - 0.00027 21.1 4.1 0.007 16.6 0.0 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX96150.1 - 0.00045 20.5 1.6 0.02 15.3 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX96150.1 - 0.0035 17.3 2.7 0.01 15.8 0.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger DUF3449 PF11931.8 ORX96150.1 - 0.036 13.9 1.5 0.057 13.2 0.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 ORX96150.1 - 0.045 14.6 4.6 4.3 8.5 1.1 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-PHD-like PF15446.6 ORX96150.1 - 0.51 9.9 6.1 0.73 9.4 3.7 1.9 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-C2H2 PF00096.26 ORX96150.1 - 2.7 8.6 8.1 4.3 8.0 1.6 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type Hira PF07569.11 ORX96151.1 - 2.2e-25 89.7 0.3 2.9e-25 89.3 0.3 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 ORX96152.1 - 1.6e-32 111.0 29.6 1.8e-07 31.7 1.2 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.11 ORX96152.1 - 1.8e-15 57.3 0.6 1.8e-15 57.3 0.6 3.0 4 0 0 4 4 4 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 ORX96152.1 - 1.8e-14 53.8 3.8 0.032 14.5 0.2 6.4 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 ORX96152.1 - 2e-07 30.7 0.2 6.8e-07 29.0 0.2 2.0 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.11 ORX96152.1 - 0.00029 20.8 3.2 0.0047 16.8 0.4 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORX96152.1 - 0.0021 16.2 4.0 0.011 13.8 0.5 2.6 3 0 0 3 3 3 2 IKI3 family Ge1_WD40 PF16529.5 ORX96152.1 - 0.0032 16.5 6.8 0.78 8.6 0.0 4.9 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2838 PF10998.8 ORX96182.1 - 1.2e-40 138.2 11.5 1.2e-40 138.2 11.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DUF454 PF04304.13 ORX96182.1 - 0.006 16.6 0.4 0.006 16.6 0.4 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF454) Orf78 PF06024.12 ORX96182.1 - 9.4 6.6 9.8 5.1 7.5 0.0 3.5 4 0 0 4 4 4 0 Orf78 (ac78) GMC_oxred_N PF00732.19 ORX96183.1 - 4.1e-52 177.4 0.8 6.2e-52 176.8 0.8 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX96183.1 - 2e-24 86.7 0.8 3.4e-24 86.0 0.0 1.8 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORX96183.1 - 1.4e-09 37.5 6.3 0.00039 19.6 2.5 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORX96183.1 - 7.2e-08 32.0 2.3 0.0041 16.4 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX96183.1 - 1.7e-05 24.6 4.4 0.005 16.5 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase GDI PF00996.18 ORX96183.1 - 0.0001 21.0 0.4 0.00016 20.3 0.1 1.5 2 0 0 2 2 2 1 GDP dissociation inhibitor HI0933_like PF03486.14 ORX96183.1 - 0.0036 16.1 3.6 0.049 12.3 0.8 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ORX96183.1 - 0.0047 17.1 3.5 0.0066 16.7 1.3 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORX96183.1 - 0.019 14.2 0.5 0.051 12.8 0.5 1.6 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 ORX96183.1 - 0.044 12.8 0.6 0.097 11.7 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORX96183.1 - 0.073 12.3 1.6 0.13 11.5 1.6 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ORX96183.1 - 0.13 11.9 1.0 0.26 10.9 1.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ORX96183.1 - 0.28 10.4 1.0 2.3 7.4 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX96183.1 - 4.7 6.4 6.0 4.1 6.6 3.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 ORX96184.1 - 2.2e-52 178.3 0.8 3.3e-52 177.7 0.8 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORX96184.1 - 1.1e-24 87.6 1.0 1.5e-24 87.1 0.0 1.7 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORX96184.1 - 4.2e-11 42.6 6.2 0.00027 20.1 2.5 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ORX96184.1 - 9e-09 35.0 2.8 0.003 16.9 0.3 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX96184.1 - 1.4e-05 24.9 4.9 0.0032 17.1 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase GDI PF00996.18 ORX96184.1 - 6.3e-05 21.7 0.4 0.00011 20.9 0.1 1.5 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 ORX96184.1 - 0.0017 18.6 1.9 0.0046 17.2 1.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORX96184.1 - 0.009 14.8 6.3 0.034 12.8 0.8 2.4 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 ORX96184.1 - 0.03 13.4 0.6 0.067 12.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ORX96184.1 - 0.035 13.3 2.2 0.036 13.3 0.5 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 ORX96184.1 - 0.038 13.2 1.2 0.062 12.5 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ORX96184.1 - 0.077 12.6 1.0 0.18 11.5 1.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ORX96184.1 - 0.15 11.3 1.1 1.6 7.9 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX96184.1 - 2.3 7.4 5.7 2.9 7.2 3.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HSD3 PF15244.6 ORX96185.1 - 0.23 10.9 4.3 0.29 10.6 4.3 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Defensin_like PF10868.8 ORX96187.1 - 2.6 8.9 15.6 1.2 9.9 5.0 2.3 2 0 0 2 2 2 0 Cysteine-rich antifungal protein 2, defensin-like CNH PF00780.22 ORX96189.1 - 1.8e-50 172.1 0.1 3.1e-50 171.3 0.1 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORX96189.1 - 7.8e-37 127.3 2.9 2.9e-36 125.4 2.9 2.0 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORX96189.1 - 2e-16 60.3 0.0 1.8e-09 37.8 0.0 2.8 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 ORX96189.1 - 2.7e-05 24.6 0.3 0.00053 20.5 0.0 3.1 3 1 1 4 4 4 1 PH domain PH_13 PF16652.5 ORX96189.1 - 0.0001 22.1 0.0 0.00041 20.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Cullin PF00888.22 ORX96190.1 - 7.9e-209 695.3 6.4 9.9e-209 695.0 6.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORX96190.1 - 1.4e-28 98.7 1.9 1.4e-28 98.7 1.9 3.7 4 0 0 4 4 4 1 Cullin protein neddylation domain Yos9_DD PF17880.1 ORX96190.1 - 0.0089 16.1 0.6 0.039 14.1 0.3 2.3 2 1 0 2 2 2 1 Yos9 dimerzation domain Tautomerase_3 PF14832.6 ORX96190.1 - 0.14 12.4 0.3 12 6.2 0.2 2.9 2 0 0 2 2 2 0 Putative oxalocrotonate tautomerase enzyme Ribosomal_S6e PF01092.19 ORX96191.1 - 1.9e-60 202.3 0.0 3.6e-60 201.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e UCR_14kD PF02271.16 ORX96192.1 - 2.1e-42 143.2 0.4 2.4e-42 143.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.11 ORX96192.1 - 0.035 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DUF2781 PF10914.8 ORX96193.1 - 2.5e-33 115.6 16.5 3.1e-33 115.3 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) O-antigen_lig PF13425.6 ORX96193.1 - 0.058 12.2 5.8 0.096 11.5 5.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sld5 PF05916.11 ORX96194.1 - 3.5e-22 78.9 2.0 4.9e-22 78.4 2.0 1.2 1 0 0 1 1 1 1 GINS complex protein IstB_IS21 PF01695.17 ORX96194.1 - 0.00077 19.2 0.0 0.0015 18.3 0.0 1.5 1 1 1 2 2 2 1 IstB-like ATP binding protein TolA_bind_tri PF16331.5 ORX96195.1 - 0.0041 17.2 1.0 0.0041 17.2 1.0 5.3 4 1 0 4 4 4 1 TolA binding protein trimerisation PRKG1_interact PF15898.5 ORX96195.1 - 0.012 16.5 14.2 0.012 16.5 14.2 5.0 4 1 0 4 4 4 0 cGMP-dependent protein kinase interacting domain MtrB PF05440.12 ORX96195.1 - 0.095 13.1 0.8 0.36 11.3 0.1 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B ORF6C PF10552.9 ORX96195.1 - 0.15 12.1 16.2 0.34 11.0 2.9 3.5 3 0 0 3 3 3 0 ORF6C domain HOOK PF05622.12 ORX96195.1 - 0.4 8.8 47.3 0.026 12.7 7.3 3.5 1 1 2 3 3 3 0 HOOK protein Fez1 PF06818.15 ORX96195.1 - 0.6 10.5 43.6 0.14 12.6 17.5 3.7 2 1 1 3 3 3 0 Fez1 DUF4407 PF14362.6 ORX96195.1 - 0.95 8.7 28.5 3.8 6.8 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Peptidase_M16 PF00675.20 ORX96195.1 - 1.4 8.8 8.3 0.15 12.0 0.5 3.1 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) LPP PF04728.13 ORX96195.1 - 4.1 7.9 9.8 45 4.5 0.1 4.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 ORX96195.1 - 7.6 7.0 17.4 0.45 10.9 0.6 4.5 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) RabGAP-TBC PF00566.18 ORX96196.1 - 1.3e-47 162.2 0.0 2.7e-47 161.2 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 ORX96196.1 - 1.2e-06 28.0 4.9 0.0019 18.0 0.4 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORX96196.1 - 1.2e-06 28.9 2.4 0.00082 19.8 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain pair GRAM PF02893.20 ORX96196.1 - 2.7e-06 27.3 3.0 3.1e-06 27.0 0.1 2.3 2 0 0 2 2 2 1 GRAM domain EF-hand_1 PF00036.32 ORX96196.1 - 0.0053 16.2 2.8 0.038 13.5 0.2 3.1 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 ORX96196.1 - 0.084 12.4 0.5 0.83 9.3 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 ORX96196.1 - 0.14 12.1 0.4 3.6 7.5 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain pair Swi3 PF07962.12 ORX96197.1 - 1.4e-28 98.7 0.9 2.4e-28 97.9 0.9 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 bMG5 PF17972.1 ORX96197.1 - 0.031 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain RF-1 PF00472.20 ORX96197.1 - 0.057 13.4 0.8 0.057 13.4 0.8 1.8 2 0 0 2 2 2 0 RF-1 domain Glycophorin_A PF01102.18 ORX96198.1 - 0.0016 18.7 0.7 0.0029 17.8 0.7 1.5 1 0 0 1 1 1 1 Glycophorin A Adeno_E3_CR2 PF02439.15 ORX96198.1 - 0.064 13.0 2.0 0.12 12.1 2.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Aconitase PF00330.20 ORX96200.1 - 1.5e-155 518.7 0.0 1.9e-155 518.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORX96200.1 - 1.2e-41 142.1 0.0 2.5e-41 141.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ORX96200.1 - 0.029 13.1 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Allantoicase PF03561.15 ORX96201.1 - 2.5e-86 286.9 0.0 1.4e-44 151.6 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat PI31_Prot_C PF08577.11 ORX96202.1 - 0.075 14.2 2.0 0.17 13.1 1.9 1.9 1 1 0 1 1 1 0 PI31 proteasome regulator DUF445 PF04286.12 ORX96203.1 - 0.0087 15.9 2.9 0.021 14.7 2.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF848 PF05852.11 ORX96203.1 - 0.15 12.2 0.3 0.33 11.1 0.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) BEN PF10523.9 ORX96203.1 - 0.17 12.2 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 BEN domain HSBP1 PF06825.12 ORX96203.1 - 0.18 11.7 0.2 0.55 10.1 0.2 1.9 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RA PF00788.23 ORX96207.1 - 2.6e-05 24.7 0.4 0.00098 19.7 0.1 2.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 ORX96207.1 - 4.1e-05 23.1 0.0 0.0001 21.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX96207.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SH3_16 PF18348.1 ORX96207.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain TUG-UBL1 PF11470.8 ORX96207.1 - 0.042 14.1 0.1 9.7 6.5 0.0 2.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain Cyclin PF08613.11 ORX96208.1 - 5.2e-09 36.7 0.1 6.1e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX96208.1 - 4.1e-05 23.3 0.1 5.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain MOSC PF03473.17 ORX96209.1 - 1.7e-31 109.0 0.0 3.1e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ORX96209.1 - 2.7e-24 85.4 0.0 4e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain PIG-X PF08320.12 ORX96209.1 - 0.045 13.7 0.6 3.5 7.5 0.1 2.4 2 1 0 2 2 2 0 PIG-X / PBN1 PCC_BT PF18140.1 ORX96209.1 - 0.054 13.8 0.1 0.087 13.2 0.1 1.4 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain RasGEF PF00617.19 ORX96210.1 - 2.7e-38 131.9 0.0 6.9e-38 130.6 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain PRIMA1 PF16101.5 ORX96210.1 - 6.5 6.8 12.4 1.9 8.5 1.2 3.7 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Chitin_synth_2 PF03142.15 ORX96212.1 - 7.8e-279 925.6 0.3 1.1e-278 925.1 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX96212.1 - 3e-12 46.9 0.1 1.5e-11 44.7 0.0 2.1 2 1 1 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX96212.1 - 8.3e-12 45.4 2.9 8.3e-12 45.4 2.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX96212.1 - 5.7e-06 25.9 0.1 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX96212.1 - 0.0033 17.3 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Metallophos PF00149.28 ORX96213.1 - 2e-37 129.7 0.7 3.5e-37 128.9 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX96213.1 - 0.0075 16.7 0.2 0.016 15.6 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORX96213.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DIOX_N PF14226.6 ORX96214.1 - 8e-21 75.0 0.0 4e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORX96214.1 - 2e-18 66.7 0.0 3.8e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1295 PF06966.12 ORX96215.1 - 3.6e-52 177.2 0.8 5.5e-52 176.6 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORX96215.1 - 1.9e-05 25.0 0.0 6.6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 ORX96215.1 - 3.7e-05 23.7 4.5 5.7e-05 23.1 0.5 2.9 2 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORX96215.1 - 0.00012 22.4 2.4 0.00042 20.7 0.0 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 ORX96215.1 - 0.042 12.6 0.8 0.056 12.2 0.2 1.6 1 1 1 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Lyase_1 PF00206.20 ORX96216.1 - 1.8e-119 398.8 0.0 2.3e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ORX96216.1 - 2.2e-27 95.2 0.1 5.2e-27 94.0 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF5344 PF17279.2 ORX96217.1 - 0.00057 20.4 3.2 0.0062 17.1 0.2 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5344) BAG PF02179.16 ORX96217.1 - 0.0039 17.6 7.2 0.0051 17.2 4.6 2.3 1 1 1 2 2 2 1 BAG domain 5_3_exonuc_N PF02739.16 ORX96217.1 - 0.04 13.8 1.1 0.098 12.6 0.2 1.8 1 1 1 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF3347 PF11827.8 ORX96217.1 - 0.11 12.7 2.2 0.13 12.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF3800 PF12686.7 ORX96217.1 - 0.12 13.0 0.3 1.1 9.9 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Syntaxin_2 PF14523.6 ORX96217.1 - 0.12 12.7 5.7 0.24 11.8 0.7 2.3 2 1 0 2 2 2 0 Syntaxin-like protein PhoU PF01895.19 ORX96217.1 - 2.8 8.5 7.1 2.8 8.4 1.0 2.9 1 1 3 4 4 4 0 PhoU domain SNARE_assoc PF09335.11 ORX96218.1 - 4.3e-22 78.8 5.0 4.3e-22 78.8 5.0 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Ribosomal_L27A PF00828.19 ORX96219.1 - 4.6e-38 130.8 4.9 6e-38 130.4 4.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NNMT_PNMT_TEMT PF01234.17 ORX96219.1 - 0.04 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PCSK9_C1 PF18459.1 ORX96219.1 - 0.15 12.2 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain TPR_1 PF00515.28 ORX96220.1 - 4.5e-23 80.0 3.9 0.00016 21.4 0.5 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORX96220.1 - 4.5e-18 63.8 4.7 4.5e-05 23.3 0.5 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX96220.1 - 2.6e-16 59.0 8.3 0.00031 20.4 1.3 5.5 2 2 3 5 5 5 4 TPR repeat TPR_8 PF13181.6 ORX96220.1 - 2.9e-14 52.0 1.1 0.0024 17.9 0.1 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORX96220.1 - 6.7e-12 44.9 11.0 0.0095 16.2 0.6 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX96220.1 - 1.2e-10 41.8 3.8 3.2e-06 27.5 1.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX96220.1 - 6.6e-10 39.1 2.8 0.008 16.4 3.5 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORX96220.1 - 1.7e-09 37.7 12.1 0.051 14.4 0.0 6.0 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORX96220.1 - 2.1e-09 37.8 3.2 0.0013 19.4 0.5 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 ORX96220.1 - 7.6e-09 35.8 8.6 0.0043 17.4 0.2 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX96220.1 - 1.4e-08 34.1 2.3 0.0037 17.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX96220.1 - 9.7e-07 28.8 3.7 0.027 14.6 0.6 3.9 2 2 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX96220.1 - 1.1e-05 25.6 4.2 4.3e-05 23.7 3.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORX96220.1 - 0.0013 19.3 2.7 2.5 8.9 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 ORX96220.1 - 0.02 13.9 1.7 0.091 11.7 0.6 2.0 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 ORX96220.1 - 0.023 15.3 0.1 0.071 13.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4248 PF14053.6 ORX96220.1 - 0.041 13.9 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4248) DUF1641 PF07849.11 ORX96220.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_10 PF13374.6 ORX96220.1 - 0.28 11.1 9.3 0.45 10.5 1.7 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.21 ORX96221.1 - 1.2e-33 115.6 0.0 1.9e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX96221.1 - 2.4e-09 37.5 16.2 3.9e-09 36.8 16.2 1.3 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 ORX96221.1 - 3.1e-06 26.6 0.0 4.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX96221.1 - 0.00028 20.6 0.9 0.0013 18.4 0.7 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF3123 PF11321.8 ORX96221.1 - 0.016 15.9 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) HAP1_N PF04849.13 ORX96241.1 - 1.4e-06 27.8 20.5 2.7e-05 23.5 20.2 2.7 1 1 0 1 1 1 1 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 ORX96241.1 - 1.2e-05 25.5 2.4 1.2e-05 25.5 2.4 3.3 2 1 1 3 3 3 1 Tropomyosin like Prefoldin_3 PF13758.6 ORX96241.1 - 0.0012 18.9 6.9 0.0051 16.8 1.7 2.8 1 1 1 2 2 2 1 Prefoldin subunit Tropomyosin PF00261.20 ORX96241.1 - 0.0037 16.7 1.5 0.0037 16.7 1.5 3.3 2 1 2 4 4 4 2 Tropomyosin Caudo_TAP PF02413.17 ORX96241.1 - 0.009 16.2 2.8 0.011 15.9 1.3 1.9 1 1 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Snapin_Pallidin PF14712.6 ORX96241.1 - 0.043 14.2 0.3 0.043 14.2 0.3 3.7 3 2 0 3 3 2 0 Snapin/Pallidin IFT57 PF10498.9 ORX96241.1 - 0.047 12.6 17.7 0.66 8.9 5.4 2.9 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 GIT_CC PF16559.5 ORX96241.1 - 0.059 13.2 0.2 0.059 13.2 0.2 2.7 3 1 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 ORX96241.1 - 0.12 11.7 2.1 0.21 10.9 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 ORX96241.1 - 0.14 12.2 15.4 0.38 10.8 4.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 ORX96241.1 - 0.19 11.5 4.8 21 4.8 4.8 2.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain COG2 PF06148.11 ORX96241.1 - 0.41 10.7 7.1 0.35 11.0 0.7 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 ORX96241.1 - 0.43 10.6 19.1 0.035 14.1 12.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 ORX96241.1 - 0.52 10.0 9.5 1 9.0 0.8 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF745) Prominin PF05478.11 ORX96241.1 - 0.69 7.8 12.8 1.1 7.1 12.8 1.4 1 1 0 1 1 1 0 Prominin ERM PF00769.19 ORX96241.1 - 0.78 9.5 17.0 0.059 13.2 11.5 1.9 2 1 0 2 2 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 ORX96241.1 - 1 9.8 15.8 1.1 9.7 12.7 2.4 1 1 1 2 2 2 0 Fez1 DHR10 PF18595.1 ORX96241.1 - 1 9.5 16.7 0.52 10.4 1.1 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 ORX96241.1 - 1.2 9.8 10.1 0.79 10.3 1.4 3.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DUF948 PF06103.11 ORX96241.1 - 1.3 9.3 7.0 1.5 9.1 0.1 3.0 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 ORX96241.1 - 1.5 8.8 12.9 0.51 10.4 3.7 3.2 1 1 1 3 3 3 0 Laminin Domain II LMBR1 PF04791.16 ORX96241.1 - 1.8 7.4 7.9 2.3 7.0 7.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 ORX96241.1 - 2.1 7.5 8.9 1.6 7.9 6.8 2.0 1 1 0 1 1 1 0 TMPIT-like protein Fzo_mitofusin PF04799.13 ORX96241.1 - 2.4 7.7 8.4 2.1 7.9 0.5 2.7 1 1 0 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 ORX96241.1 - 3.9 7.7 17.9 27 4.9 7.9 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family LPP PF04728.13 ORX96241.1 - 4.7 7.7 6.4 3.6 8.0 0.1 3.6 3 1 1 4 4 4 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 ORX96241.1 - 8.8 6.4 23.3 1.2 9.2 11.0 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Complex1_30kDa PF00329.19 ORX96242.1 - 1.8e-46 157.7 0.0 2.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Ribosomal_L31 PF01197.18 ORX96243.1 - 2.3e-09 37.4 0.0 6.4e-09 35.9 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L31 Sec10 PF07393.11 ORX96244.1 - 5.5e-114 382.1 0.0 4e-83 280.1 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 F-box PF00646.33 ORX96244.1 - 2.1e-05 24.2 0.5 4.7e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORX96244.1 - 3.5e-05 23.6 0.5 7.7e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like Transthyretin PF00576.21 ORX96245.1 - 2.2e-39 134.5 0.1 2.5e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MRP-S25 PF13741.6 ORX96246.1 - 2.8e-50 171.0 4.4 3.2e-50 170.8 4.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ORX96246.1 - 0.00019 21.7 1.8 0.012 15.8 1.5 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Scm3 PF10384.9 ORX96247.1 - 1.3e-14 53.6 0.1 4.9e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 DUF5435 PF17503.2 ORX96247.1 - 0.012 15.4 1.6 0.016 15.0 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5435) Cgr1 PF03879.14 ORX96248.1 - 3.7e-23 81.9 26.0 4.5e-23 81.7 26.0 1.1 1 0 0 1 1 1 1 Cgr1 family DUF2514 PF10721.9 ORX96248.1 - 0.051 13.6 13.1 0.064 13.3 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RbsD_FucU PF05025.13 ORX96248.1 - 0.19 12.1 2.5 0.26 11.7 2.5 1.2 1 0 0 1 1 1 0 RbsD / FucU transport protein family FOXP-CC PF16159.5 ORX96248.1 - 0.69 10.6 7.6 0.86 10.3 0.9 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Exonuc_VII_L PF02601.15 ORX96248.1 - 1.1 8.8 8.7 1.1 8.8 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 ORX96248.1 - 1.6 9.1 17.4 1.9 8.8 17.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.14 ORX96248.1 - 4.5 6.4 22.6 5.3 6.2 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Robl_LC7 PF03259.17 ORX96249.1 - 8.4e-22 76.8 0.0 9e-22 76.7 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 ORX96249.1 - 1e-05 25.3 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 ORX96249.1 - 0.0077 16.6 0.1 0.0097 16.2 0.1 1.2 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Nas2_N PF18265.1 ORX96249.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nas2 N_terminal domain SMC_N PF02463.19 ORX96250.1 - 8e-25 87.6 0.0 2.3e-24 86.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX96250.1 - 5.7e-18 66.2 6.0 5.7e-18 66.2 6.0 4.8 2 2 2 4 4 3 1 AAA domain AAA_15 PF13175.6 ORX96250.1 - 9.8e-05 22.2 14.9 9.8e-05 22.2 14.9 4.0 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 ORX96250.1 - 0.00034 20.3 0.0 0.00085 19.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORX96250.1 - 0.00067 19.6 8.1 0.0034 17.2 0.2 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 ORX96250.1 - 0.099 12.2 0.0 0.099 12.2 0.0 4.0 4 1 2 6 6 6 0 AAA domain ABC_tran PF00005.27 ORX96250.1 - 0.11 13.0 0.1 0.11 13.0 0.1 5.2 3 2 0 4 4 2 0 ABC transporter AAA_25 PF13481.6 ORX96250.1 - 0.12 12.0 0.9 0.56 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORX96250.1 - 0.18 12.2 2.1 0.66 10.4 0.1 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1664 PF07889.12 ORX96250.1 - 0.4 10.7 0.0 0.4 10.7 0.0 6.0 6 1 2 8 8 8 0 Protein of unknown function (DUF1664) NAD_binding_5 PF07994.12 ORX96250.1 - 2.4 7.4 6.8 3.2 7.0 3.5 2.7 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase HSBP1 PF06825.12 ORX96250.1 - 2.9 7.8 8.3 1.4 8.8 1.3 3.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Cnd2 PF05786.14 ORX96251.1 - 1.5e-175 586.1 30.3 9.4e-174 580.1 30.3 2.1 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 ORX96251.1 - 0.0066 16.6 0.0 0.032 14.4 0.0 2.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4484 PF14831.6 ORX96251.1 - 1.4 8.9 6.0 1.1 9.2 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Coq4 PF05019.13 ORX96252.1 - 2.6e-96 321.2 0.0 3e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SUI1 PF01253.22 ORX96253.1 - 2.4e-22 79.2 0.1 2.4e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 CSRNP_N PF16019.5 ORX96253.1 - 0.045 13.7 2.2 0.06 13.2 2.2 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus MRP-L46 PF11788.8 ORX96254.1 - 8.4e-15 55.6 0.6 6.9e-14 52.6 0.1 2.5 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 ORX96254.1 - 1.7e-08 34.6 0.3 4.6e-08 33.2 0.2 1.7 1 1 1 2 2 2 1 NUDIX domain WD40 PF00400.32 ORX96255.1 - 3.7e-61 201.6 13.1 8.1e-09 36.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORX96255.1 - 8e-30 103.0 8.2 1.2e-29 102.4 8.2 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORX96255.1 - 5.1e-23 81.2 0.0 0.00027 21.2 0.0 6.5 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX96255.1 - 3.6e-11 43.0 0.0 0.0041 16.5 0.0 4.8 3 2 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 ORX96255.1 - 7.6e-10 38.3 0.6 0.29 10.0 0.0 5.2 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX96255.1 - 5.8e-07 28.5 0.2 0.12 11.0 0.0 4.5 3 1 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 ORX96255.1 - 2.1e-06 27.8 0.0 0.18 11.7 0.0 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORX96255.1 - 5.9e-06 26.1 0.6 13 5.8 0.0 5.0 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 ORX96255.1 - 0.00015 21.2 0.1 3.6 6.8 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 ORX96255.1 - 0.00016 20.3 0.2 0.024 13.2 0.1 2.5 1 1 0 2 2 2 1 Cytochrome D1 heme domain Spc7 PF08317.11 ORX96255.1 - 0.01 14.7 3.4 0.015 14.2 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CEP63 PF17045.5 ORX96255.1 - 0.057 13.3 5.2 0.093 12.6 5.2 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Golgin_A5 PF09787.9 ORX96255.1 - 0.058 12.8 4.4 0.09 12.2 4.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Proteasome_A_N PF10584.9 ORX96255.1 - 0.11 12.3 3.3 34 4.3 0.1 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature MMS1_N PF10433.9 ORX96255.1 - 0.12 11.0 0.0 3.6 6.1 0.0 2.4 2 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF3450 PF11932.8 ORX96255.1 - 0.32 10.3 5.9 0.54 9.5 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPX2 PF06886.11 ORX96255.1 - 0.72 10.1 6.0 1.3 9.3 6.0 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) APG6_N PF17675.1 ORX96255.1 - 1.5 9.3 6.4 2.6 8.6 6.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Mitofilin PF09731.9 ORX96255.1 - 2.1 7.1 7.0 3.1 6.5 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PMSR PF01625.21 ORX96256.1 - 7.7e-63 211.2 7.3 8.9e-63 211.0 7.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase T5orf172 PF10544.9 ORX96257.1 - 9.7e-18 64.6 0.0 1.3e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ORX96257.1 - 6.3e-17 62.0 0.0 9.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 FapA PF03961.13 ORX96258.1 - 0.0048 15.6 0.3 0.0048 15.6 0.3 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A GAS PF13851.6 ORX96258.1 - 0.0077 15.6 4.1 0.0097 15.3 4.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 ORX96258.1 - 0.017 15.2 2.7 0.017 15.2 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlgN PF05130.12 ORX96258.1 - 0.024 15.2 1.1 0.037 14.5 1.1 1.2 1 0 0 1 1 1 0 FlgN protein LdpA_C PF12617.8 ORX96258.1 - 0.025 14.2 0.2 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal DUF4559 PF15112.6 ORX96258.1 - 0.028 14.1 1.0 0.037 13.7 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Uds1 PF15456.6 ORX96258.1 - 0.036 14.2 3.7 0.29 11.3 0.5 2.1 1 1 1 2 2 2 0 Up-regulated During Septation BLOC1_2 PF10046.9 ORX96258.1 - 0.046 14.0 3.5 0.11 12.8 0.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.14 ORX96258.1 - 0.089 12.7 3.0 0.13 12.1 3.0 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PCRF PF03462.18 ORX96258.1 - 0.089 12.6 2.6 0.12 12.3 2.6 1.1 1 0 0 1 1 1 0 PCRF domain Tup_N PF08581.10 ORX96258.1 - 0.14 12.5 4.0 0.26 11.6 3.9 1.6 1 1 0 1 1 1 0 Tup N-terminal Tho2 PF11262.8 ORX96258.1 - 0.31 10.2 4.4 0.42 9.8 4.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Phage_HK97_TLTM PF06120.11 ORX96258.1 - 0.75 8.9 9.1 1.9 7.6 9.1 1.7 1 1 0 1 1 1 0 Tail length tape measure protein DUF2678 PF10856.8 ORX96260.1 - 6.7e-16 58.3 1.7 7.2e-16 58.2 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Pyrophosphatase PF00719.19 ORX96261.1 - 1.3e-58 197.3 0.1 1.8e-58 196.9 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ecl1 PF12855.7 ORX96262.1 - 1.8e-09 39.0 0.9 2.4e-09 38.6 0.9 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 ORX96262.1 - 0.0024 18.5 3.4 0.0043 17.7 3.4 1.4 1 0 0 1 1 1 1 PLATZ transcription factor DUF2116 PF09889.9 ORX96262.1 - 2.2 8.3 5.5 3 7.9 3.7 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Fasciclin PF02469.22 ORX96263.1 - 9.9e-43 145.4 1.1 3.9e-23 82.1 0.2 2.1 2 0 0 2 2 2 2 Fasciclin domain zf-H2C2_2 PF13465.6 ORX96264.1 - 4.2e-17 61.7 16.6 3.4e-09 36.7 0.8 3.6 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX96264.1 - 4.8e-15 55.1 20.0 3.6e-05 24.0 2.6 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96264.1 - 7.3e-12 45.1 16.8 0.00054 20.6 1.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX96264.1 - 6.5e-09 35.6 18.0 8.6e-05 22.4 0.1 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96264.1 - 1.3e-06 28.6 4.2 0.033 14.5 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX96264.1 - 2.7e-05 24.4 4.3 3.2e-05 24.1 1.9 2.0 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 ORX96264.1 - 0.00014 22.2 12.4 0.44 11.0 1.6 3.2 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORX96264.1 - 0.0012 18.5 6.7 0.15 11.8 0.1 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_ZIC PF18366.1 ORX96264.1 - 0.0022 18.1 3.9 1.4 9.1 0.1 3.2 2 1 1 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 ORX96264.1 - 0.0091 16.7 4.6 0.049 14.3 4.4 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 ORX96264.1 - 0.0097 16.0 10.6 0.095 12.8 0.2 3.3 2 1 1 3 3 3 1 Zinc ribbon domain zf-LYAR PF08790.11 ORX96264.1 - 0.039 13.9 8.5 9.7 6.2 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger BolA PF01722.18 ORX96264.1 - 0.042 14.1 0.5 2.8 8.3 0.3 2.2 1 1 1 2 2 2 0 BolA-like protein zf-AN1 PF01428.16 ORX96264.1 - 0.081 13.1 14.0 1.2 9.4 3.4 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger RNHCP PF12647.7 ORX96264.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.8 2 1 1 3 3 3 0 RNHCP domain zf_UBZ PF18439.1 ORX96264.1 - 0.5 10.0 6.0 5.3 6.7 0.5 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 ORX96264.1 - 0.5 10.3 5.0 7.9 6.4 0.1 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) IBR PF01485.21 ORX96264.1 - 0.76 10.0 7.4 1.1 9.6 4.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 ORX96264.1 - 0.86 9.9 8.7 0.94 9.8 3.5 2.6 1 1 1 3 3 3 0 TFIIH C1-like domain DUF2757 PF10955.8 ORX96264.1 - 1 9.7 5.1 4.2 7.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) PyrI_C PF02748.15 ORX96264.1 - 1 9.3 3.8 9.9 6.2 1.2 3.0 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 ORX96264.1 - 1.6 9.2 7.3 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HypA PF01155.19 ORX96264.1 - 2.6 8.1 5.1 1.7 8.7 2.6 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 ORX96264.1 - 3.1 8.2 9.2 1.2 9.5 0.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 ORX96264.1 - 7.7 6.6 7.3 66 3.6 2.9 3.0 1 1 1 2 2 2 0 CpXC protein zf-H2C2_2 PF13465.6 ORX96265.1 - 4.2e-17 61.7 16.6 3.4e-09 36.7 0.8 3.6 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX96265.1 - 4.8e-15 55.1 20.0 3.6e-05 24.0 2.6 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96265.1 - 7.3e-12 45.1 16.8 0.00054 20.6 1.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX96265.1 - 6.5e-09 35.6 18.0 8.6e-05 22.4 0.1 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96265.1 - 1.3e-06 28.6 4.2 0.033 14.5 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX96265.1 - 2.7e-05 24.4 4.3 3.2e-05 24.1 1.9 2.0 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 ORX96265.1 - 0.00014 22.2 12.4 0.44 11.0 1.6 3.2 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORX96265.1 - 0.0012 18.5 6.7 0.15 11.8 0.1 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_ZIC PF18366.1 ORX96265.1 - 0.0022 18.1 3.9 1.4 9.1 0.1 3.2 2 1 1 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 ORX96265.1 - 0.0091 16.7 4.6 0.049 14.3 4.4 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 ORX96265.1 - 0.0097 16.0 10.6 0.095 12.8 0.2 3.3 2 1 1 3 3 3 1 Zinc ribbon domain zf-LYAR PF08790.11 ORX96265.1 - 0.039 13.9 8.5 9.7 6.2 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger BolA PF01722.18 ORX96265.1 - 0.042 14.1 0.5 2.8 8.3 0.3 2.2 1 1 1 2 2 2 0 BolA-like protein zf-AN1 PF01428.16 ORX96265.1 - 0.081 13.1 14.0 1.2 9.4 3.4 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger RNHCP PF12647.7 ORX96265.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.8 2 1 1 3 3 3 0 RNHCP domain zf_UBZ PF18439.1 ORX96265.1 - 0.5 10.0 6.0 5.3 6.7 0.5 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 ORX96265.1 - 0.5 10.3 5.0 7.9 6.4 0.1 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) IBR PF01485.21 ORX96265.1 - 0.76 10.0 7.4 1.1 9.6 4.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 ORX96265.1 - 0.86 9.9 8.7 0.94 9.8 3.5 2.6 1 1 1 3 3 3 0 TFIIH C1-like domain DUF2757 PF10955.8 ORX96265.1 - 1 9.7 5.1 4.2 7.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) PyrI_C PF02748.15 ORX96265.1 - 1 9.3 3.8 9.9 6.2 1.2 3.0 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 ORX96265.1 - 1.6 9.2 7.3 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HypA PF01155.19 ORX96265.1 - 2.6 8.1 5.1 1.7 8.7 2.6 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 ORX96265.1 - 3.1 8.2 9.2 1.2 9.5 0.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 ORX96265.1 - 7.7 6.6 7.3 66 3.6 2.9 3.0 1 1 1 2 2 2 0 CpXC protein YhhN PF07947.14 ORX96267.1 - 1.4e-38 132.4 8.9 2e-38 131.9 8.9 1.2 1 0 0 1 1 1 1 YhhN family DPM3 PF08285.11 ORX96267.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.8 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MAAL_C PF07476.11 ORX96268.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Ribosomal_S5 PF00333.20 ORX96269.1 - 1.3e-29 102.0 0.4 1.3e-29 102.0 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX96269.1 - 3.2e-26 90.6 0.1 5.2e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORX96269.1 - 0.77 10.3 10.5 1.5 9.4 10.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Polysacc_deac_1 PF01522.21 ORX96270.1 - 7.7e-34 116.3 0.0 8.4e-33 112.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORX96270.1 - 0.00031 20.5 0.2 0.024 14.3 0.1 2.3 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX96270.1 - 0.00052 19.3 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 zf-RAG1 PF10426.9 ORX96270.1 - 0.15 12.2 2.7 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain bZIP_2 PF07716.15 ORX96271.1 - 1.5e-10 41.0 11.7 2.3e-10 40.4 11.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX96271.1 - 0.0032 17.5 8.7 0.0057 16.7 8.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 ORX96271.1 - 0.057 13.6 5.2 0.083 13.1 5.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TspO_MBR PF03073.15 ORX96272.1 - 1.1e-45 154.9 20.6 1.3e-45 154.7 20.6 1.0 1 0 0 1 1 1 1 TspO/MBR family SAM_1 PF00536.30 ORX96273.1 - 1.6e-14 54.1 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORX96273.1 - 2.5e-10 40.3 0.0 2.8e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 ORX96273.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.4 1 1 0 1 1 1 0 IGR protein motif NCD1 PF04904.13 ORX96273.1 - 0.12 12.3 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 NAB conserved region 1 (NCD1) HMG_box PF00505.19 ORX96274.1 - 2.2e-13 50.4 0.8 2.2e-13 50.4 0.8 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX96274.1 - 5.4e-10 39.7 2.2 6.1e-10 39.6 1.3 1.6 1 1 0 1 1 1 1 HMG-box domain MlaC PF05494.12 ORX96274.1 - 0.0063 16.3 0.1 0.0082 15.9 0.1 1.2 1 0 0 1 1 1 1 MlaC protein Phe_tRNA-synt_N PF02912.18 ORX96274.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain RIB43A PF05914.12 ORX96274.1 - 0.014 14.2 1.3 0.016 14.0 1.3 1.1 1 0 0 1 1 1 0 RIB43A WYL_3 PF18488.1 ORX96274.1 - 0.031 14.7 1.1 0.055 13.8 1.1 1.4 1 0 0 1 1 1 0 WYL domain VIR_N PF15912.5 ORX96274.1 - 0.38 10.3 5.1 0.46 10.0 5.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Peptidase_M76 PF09768.9 ORX96275.1 - 1.6e-32 112.6 6.7 2.5e-32 112.0 6.7 1.3 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 ORX96275.1 - 0.0083 16.0 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 SprT-like family Aspzincin_M35 PF14521.6 ORX96275.1 - 0.052 14.1 0.1 0.097 13.2 0.1 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Toxin_17 PF08086.11 ORX96275.1 - 0.19 12.0 2.8 0.72 10.2 1.2 2.5 2 0 0 2 2 2 0 Ergtoxin family RhoGAP PF00620.27 ORX96276.1 - 4.9e-18 65.4 0.0 2.3e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORX96276.1 - 8.3e-15 54.8 0.2 3.9e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 ORX96276.1 - 2.7e-07 30.5 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1967 PF09269.11 ORX96276.1 - 0.029 14.3 0.1 0.53 10.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) PTRF_SDPR PF15237.6 ORX96276.1 - 0.11 12.1 3.7 0.88 9.1 0.2 2.9 3 0 0 3 3 3 0 PTRF/SDPR family BAR_3 PF16746.5 ORX96276.1 - 0.37 10.5 7.1 0.16 11.7 1.1 2.3 2 0 0 2 2 2 0 BAR domain of APPL family FIST_C PF10442.9 ORX96277.1 - 0.015 15.3 0.3 0.041 13.8 0.1 1.8 2 0 0 2 2 2 0 FIST C domain Fmp27_WPPW PF10359.9 ORX96277.1 - 0.05 12.4 2.5 0.098 11.5 2.5 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF724 PF05266.14 ORX96277.1 - 0.16 11.8 3.9 0.25 11.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LsmAD PF06741.13 ORX96277.1 - 0.21 12.2 3.2 13 6.5 0.7 2.7 2 0 0 2 2 2 0 LsmAD domain DUF2183 PF09949.9 ORX96278.1 - 0.0042 17.4 0.0 0.0075 16.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Chitin_synth_1 PF01644.17 ORX96279.1 - 8.7e-73 243.7 0.2 1.4e-72 243.0 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORX96279.1 - 4e-30 104.9 2.4 4e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORX96279.1 - 3.9e-28 97.2 1.2 8.8e-28 96.1 0.1 2.2 3 0 0 3 3 3 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORX96279.1 - 4.3e-08 33.3 0.3 4.3e-08 33.3 0.3 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX96279.1 - 0.0038 17.2 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CitMHS PF03600.16 ORX96279.1 - 0.073 12.3 1.9 0.17 11.0 1.9 1.6 1 1 0 1 1 1 0 Citrate transporter CHAP PF05257.16 ORX96280.1 - 6.9e-11 42.6 2.5 1.1e-10 42.0 2.5 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX96281.1 - 6.8e-11 42.6 2.5 1.1e-10 42.0 2.5 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX96282.1 - 6.8e-11 42.6 2.5 1.1e-10 42.0 2.5 1.3 1 0 0 1 1 1 1 CHAP domain Kp4 PF09044.10 ORX96283.1 - 7.4e-28 97.1 4.9 8.9e-28 96.9 4.9 1.0 1 0 0 1 1 1 1 Kp4 Ras PF00071.22 ORX96310.1 - 1.4e-33 115.8 0.0 1.7e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX96310.1 - 1.8e-25 89.5 0.0 2.6e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX96310.1 - 7.7e-08 32.0 0.0 9.7e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX96310.1 - 1.9e-06 27.4 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX96310.1 - 0.0027 17.2 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 ORX96310.1 - 0.0076 15.4 0.5 0.074 12.2 0.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit DLIC PF05783.11 ORX96310.1 - 0.0093 14.8 0.1 1.7 7.4 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 ORX96310.1 - 0.022 14.1 0.0 4.7 6.6 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein MMR_HSR1 PF01926.23 ORX96310.1 - 0.028 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORX96310.1 - 0.071 12.8 0.1 0.23 11.2 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF445 PF04286.12 ORX96311.1 - 0.034 14.0 0.5 0.086 12.6 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) QIL1 PF15884.5 ORX96311.1 - 0.069 13.8 0.0 10 6.8 0.0 3.2 3 0 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 FAST_2 PF08368.12 ORX96311.1 - 0.088 13.6 0.0 0.65 10.8 0.0 2.3 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Baculo_PEP_C PF04513.12 ORX96311.1 - 0.2 11.7 5.7 0.64 10.1 0.2 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSF_DNA-bind PF00447.17 ORX96313.1 - 1e-33 115.8 1.7 1e-33 115.8 1.7 2.2 2 1 1 3 3 3 1 HSF-type DNA-binding HAUS6_N PF14661.6 ORX96313.1 - 0.0073 15.9 0.3 0.01 15.4 0.3 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus HD_assoc PF13286.6 ORX96313.1 - 0.028 14.9 0.4 0.062 13.8 0.4 1.5 1 0 0 1 1 1 0 Phosphohydrolase-associated domain CortBP2 PF09727.9 ORX96313.1 - 0.04 13.8 6.2 0.064 13.2 6.2 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 DUF3450 PF11932.8 ORX96313.1 - 0.072 12.4 6.9 0.1 11.9 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cob_adeno_trans PF01923.18 ORX96313.1 - 0.075 13.2 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Vps53_N PF04100.12 ORX96313.1 - 0.22 10.5 3.5 0.4 9.6 3.5 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal SseC PF04888.12 ORX96313.1 - 0.3 10.6 8.0 0.43 10.1 8.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Robl_LC7 PF03259.17 ORX96314.1 - 9.7e-15 54.1 0.2 1.5e-14 53.5 0.2 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Class_IIIsignal PF04021.12 ORX96314.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Class III signal peptide Allantoicase PF03561.15 ORX96315.1 - 1.2e-90 300.9 0.0 8.7e-47 158.7 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Aminotran_1_2 PF00155.21 ORX96316.1 - 2.2e-76 257.4 0.0 3.3e-76 256.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX96316.1 - 0.00013 20.6 0.0 0.00023 19.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORX96316.1 - 0.00016 20.7 0.0 0.00046 19.3 0.0 1.8 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORX96316.1 - 0.1 11.9 0.2 0.54 9.5 0.2 2.1 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_S30 PF04758.14 ORX96317.1 - 4.1e-29 100.6 9.6 4.4e-29 100.4 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 eIF-1a PF01176.19 ORX96318.1 - 7.9e-24 83.3 0.1 1.1e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PPR_2 PF13041.6 ORX96319.1 - 1.1e-152 496.1 45.9 1.2e-16 60.6 0.0 14.0 1 1 13 14 14 14 14 PPR repeat family PPR_1 PF12854.7 ORX96319.1 - 6.8e-103 336.0 6.7 2.5e-10 39.8 0.0 14.8 14 1 0 14 14 14 13 PPR repeat PPR PF01535.20 ORX96319.1 - 2.4e-101 325.2 18.8 1.2e-07 31.5 0.1 14.4 14 0 0 14 14 14 14 PPR repeat PPR_3 PF13812.6 ORX96319.1 - 2.4e-90 296.6 44.7 5e-12 45.7 0.1 9.4 3 3 9 12 12 12 12 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX96319.1 - 2.5e-44 151.2 13.8 3.7e-12 46.1 0.2 5.1 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX96319.1 - 3.5e-14 52.3 1.2 5.5 8.1 0.0 11.0 4 4 8 12 12 12 1 Tetratricopeptide repeat RPM2 PF08579.11 ORX96319.1 - 1.7e-12 47.8 29.4 0.0011 19.4 0.1 10.0 3 2 8 11 11 11 3 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORX96319.1 - 6.5e-10 38.4 13.6 0.003 16.5 0.8 6.4 2 2 5 7 7 7 3 Mitochondrial 28S ribosomal protein S27 TPR_1 PF00515.28 ORX96319.1 - 6.2e-08 32.1 4.7 0.096 12.5 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX96319.1 - 2e-07 30.5 1.2 3.1 8.0 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX96319.1 - 3.7e-07 30.5 4.5 1.1 9.8 0.0 7.5 5 4 2 7 7 7 1 Tetratricopeptide repeat ATP13 PF12921.7 ORX96319.1 - 0.00015 21.5 9.6 0.44 10.4 0.2 6.1 3 2 4 7 7 7 1 Mitochondrial ATPase expression DUF4817 PF16087.5 ORX96319.1 - 0.00049 19.8 0.0 0.68 9.8 0.0 4.4 5 0 0 5 5 5 1 Helix-turn-helix domain (DUF4817) GBP_C PF02841.14 ORX96319.1 - 0.0042 16.5 2.7 0.34 10.3 0.2 3.6 3 1 1 4 4 4 1 Guanylate-binding protein, C-terminal domain Ribonuc_red_lgN PF00317.21 ORX96319.1 - 0.011 15.7 14.3 15 5.7 0.8 6.5 2 2 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain RhoGAP-FF1 PF16512.5 ORX96319.1 - 0.022 15.4 7.0 46 4.8 0.0 6.4 5 2 1 7 7 6 0 p190-A and -B Rho GAPs FF domain MA3 PF02847.17 ORX96319.1 - 0.085 12.9 6.2 1.8 8.6 0.5 4.9 3 2 2 5 5 5 0 MA3 domain AAA_17 PF13207.6 ORX96319.1 - 0.15 12.5 0.2 84 3.6 0.0 4.2 2 2 3 5 5 5 0 AAA domain BTAD PF03704.17 ORX96319.1 - 0.28 11.6 5.4 8.7 6.8 0.2 4.8 6 1 0 6 6 4 0 Bacterial transcriptional activator domain Prp18 PF02840.15 ORX96319.1 - 0.54 10.3 10.4 6.5 6.8 0.2 5.1 2 2 1 4 4 4 0 Prp18 domain TPR_12 PF13424.6 ORX96319.1 - 1.2 9.5 6.1 32 4.9 0.1 5.3 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX96319.1 - 3.9 7.8 16.0 40 4.7 0.0 7.4 11 0 0 11 11 8 0 Tetratricopeptide repeat FlbT PF07378.11 ORX96319.1 - 6.8 6.8 12.1 9 6.4 0.2 4.6 3 1 1 5 5 5 0 Flagellar protein FlbT Lipase_3 PF01764.25 ORX96320.1 - 4.6e-33 114.1 0.0 6.7e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX96320.1 - 0.001 18.7 0.1 0.0071 15.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX96320.1 - 0.0052 17.4 0.0 0.0073 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX96320.1 - 0.021 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORX96320.1 - 0.05 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX96320.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ada_Zn_binding PF02805.16 ORX96321.1 - 9.3e-30 102.5 7.0 9.3e-30 102.5 7.0 1.5 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_18 PF12833.7 ORX96321.1 - 1.3e-10 41.4 0.4 4.3e-05 23.7 0.1 1.6 1 1 1 2 2 2 2 Helix-turn-helix domain HTH_AraC PF00165.23 ORX96321.1 - 7.1e-09 35.6 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 ORX96321.1 - 0.035 14.5 0.3 0.21 11.9 0.2 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain DNA_pol_B PF00136.21 ORX96323.1 - 3.6e-13 49.0 0.1 3.7e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DUF763 PF05559.11 ORX96324.1 - 0.034 13.3 0.2 0.04 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) PhyH PF05721.13 ORX96325.1 - 1.7e-26 93.8 0.0 2.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORX96325.1 - 0.041 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PAP2 PF01569.21 ORX96326.1 - 3.3e-27 94.9 0.9 3.3e-27 94.9 0.9 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX96326.1 - 0.0084 15.8 10.3 0.13 11.9 6.7 2.9 1 1 1 2 2 2 1 PAP2 superfamily Photo_RC PF00124.19 ORX96326.1 - 0.016 14.4 1.4 0.029 13.6 1.4 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre protein DUF3094 PF11293.8 ORX96326.1 - 0.37 10.5 1.7 0.74 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DotU PF09850.9 ORX96326.1 - 0.42 10.3 1.6 12 5.5 0.0 2.8 3 0 0 3 3 3 0 Type VI secretion system protein DotU Peptidase_U4 PF03419.13 ORX96326.1 - 1.5 8.0 10.9 0.67 9.2 0.2 3.0 1 1 2 3 3 3 0 Sporulation factor SpoIIGA PAP2_C PF14360.6 ORX96326.1 - 1.6 9.3 10.9 0.18 12.4 1.2 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Polysacc_synt_C PF14667.6 ORX96326.1 - 3.4 7.7 10.0 1.4 9.0 3.2 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain PAP2 PF01569.21 ORX96327.1 - 1.4e-27 96.1 0.9 1.4e-27 96.1 0.9 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX96327.1 - 0.011 15.5 6.1 0.045 13.4 6.1 2.0 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.6 ORX96327.1 - 0.099 13.2 7.4 0.097 13.2 1.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Peptidase_U4 PF03419.13 ORX96327.1 - 0.94 8.7 9.6 0.45 9.8 0.2 2.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Polysacc_synt_C PF14667.6 ORX96327.1 - 1.1 9.3 7.9 0.79 9.8 3.2 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PhyH PF05721.13 ORX96328.1 - 1.7e-26 93.8 0.0 2.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORX96328.1 - 0.04 14.3 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase HD PF01966.22 ORX96329.1 - 4e-07 30.3 0.0 6.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 ORX96329.1 - 0.00068 19.4 1.3 0.0013 18.5 1.3 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 ORX96329.1 - 0.0038 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 HDOD domain MIOX PF05153.15 ORX96329.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Myo-inositol oxygenase Peptidase_M16_M PF16187.5 ORX96330.1 - 1.3e-102 342.9 0.7 1.3e-102 342.9 0.7 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORX96330.1 - 6.5e-45 152.8 1.0 4.7e-43 146.7 0.1 3.4 3 1 1 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORX96330.1 - 6.3e-37 127.4 0.1 5.4e-23 81.9 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF4363 PF14276.6 ORX96330.1 - 1.4 9.1 4.8 0.53 10.4 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Pro_CA PF00484.19 ORX96331.1 - 8.5e-52 175.6 0.3 1.1e-51 175.3 0.3 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 ORX96332.1 - 1e-51 175.3 2.1 1.4e-51 174.9 2.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PHD_2 PF13831.6 ORX96332.1 - 0.56 9.8 0.0 0.56 9.8 0.0 3.5 4 1 0 4 4 4 0 PHD-finger Sua5_yciO_yrdC PF01300.18 ORX96333.1 - 6.7e-55 185.4 0.0 9.8e-55 184.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ORX96333.1 - 6.5e-30 104.4 0.1 9e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding UPF0047 PF01894.17 ORX96334.1 - 9.3e-37 125.7 0.0 1.1e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GCV_T_C PF08669.11 ORX96334.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Med17 PF10156.9 ORX96335.1 - 6.4e-69 232.9 5.5 8.1e-69 232.5 5.5 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Abhydro_lipase PF04083.16 ORX96336.1 - 2.1e-20 72.1 0.0 3.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORX96336.1 - 9e-19 68.1 0.1 1.3e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX96336.1 - 4.8e-06 26.0 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX96336.1 - 0.0055 17.3 0.0 0.0073 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 ORX96336.1 - 0.048 12.3 0.6 0.16 10.6 0.6 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ORX96336.1 - 0.13 12.0 0.6 1.5 8.6 0.1 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase ABC_membrane PF00664.23 ORX96337.1 - 1.1e-61 209.0 24.2 5e-34 118.2 7.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX96337.1 - 4.4e-53 179.5 0.0 9.2e-31 107.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX96337.1 - 1.2e-07 31.4 5.9 0.00013 21.5 0.2 4.2 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX96337.1 - 2.1e-05 24.2 0.5 0.17 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORX96337.1 - 2.4e-05 24.3 0.0 0.018 15.0 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 ORX96337.1 - 7.6e-05 23.3 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORX96337.1 - 0.00043 19.9 0.1 0.97 9.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ORX96337.1 - 0.0019 18.5 1.0 0.2 11.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORX96337.1 - 0.003 17.6 0.7 0.39 10.8 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX96337.1 - 0.011 16.1 0.3 3 8.2 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 ORX96337.1 - 0.02 15.0 0.8 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain T2SSE PF00437.20 ORX96337.1 - 0.039 13.0 0.0 3.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 ORX96337.1 - 0.041 13.2 0.5 9.4 5.5 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 ORX96337.1 - 0.14 11.5 0.3 8.8 5.6 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 ORX96337.1 - 0.15 11.6 0.1 11 5.4 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_27 PF13514.6 ORX96337.1 - 0.15 11.6 0.0 2.1 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 ORX96337.1 - 0.21 11.3 1.6 4.1 7.1 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_21 PF13304.6 ORX96337.1 - 0.31 10.8 5.5 5.6 6.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system GPI-anchored PF10342.9 ORX96338.1 - 8.8e-10 39.2 0.0 1e-09 39.0 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_31 PF13847.6 ORX96339.1 - 7.5e-25 87.5 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX96339.1 - 7.6e-13 49.0 0.0 1.3e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX96339.1 - 1.5e-10 41.6 0.0 2.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX96339.1 - 1.3e-07 31.6 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX96339.1 - 2.4e-06 27.0 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORX96339.1 - 7.3e-06 26.7 0.0 1.2e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX96339.1 - 2.2e-05 24.3 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ORX96339.1 - 0.032 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MFS_1 PF07690.16 ORX96340.1 - 6.8e-18 64.7 26.2 9.1e-18 64.3 26.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX96340.1 - 7.2e-14 51.8 9.2 7.2e-14 51.8 9.2 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX96340.1 - 5.1e-05 22.3 0.0 0.035 13.0 6.2 2.1 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORX96340.1 - 0.024 13.6 10.4 0.093 11.7 10.0 2.1 2 1 0 2 2 2 0 PUCC protein DctQ PF04290.12 ORX96340.1 - 0.82 9.6 0.0 0.82 9.6 0.0 4.7 3 2 1 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component CPP1-like PF11833.8 ORX96340.1 - 7.9 6.1 6.4 1.6 8.4 2.3 2.0 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Oxidored_FMN PF00724.20 ORX96341.1 - 8.3e-15 54.9 0.1 8.7e-15 54.8 0.1 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CBAH PF02275.18 ORX96367.1 - 0.091 12.4 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Amidohydro_1 PF01979.20 ORX96368.1 - 8.9e-21 74.6 0.0 1.7e-20 73.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX96368.1 - 9.5e-07 28.6 0.1 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Cyclin_N PF00134.23 ORX96369.1 - 1.9e-12 47.0 1.2 3.5e-12 46.2 0.2 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain CBM_14 PF01607.24 ORX96370.1 - 0.034 14.3 4.7 0.064 13.4 4.7 1.5 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Dicty_CAR PF05462.11 ORX96371.1 - 7.1e-23 81.2 19.1 9.4e-23 80.8 19.1 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor CbiQ PF02361.16 ORX96371.1 - 1.5 8.3 12.5 1.2 8.7 8.6 2.2 2 0 0 2 2 2 0 Cobalt transport protein zf-C2H2_aberr PF17017.5 ORX96372.1 - 2.5e-07 31.0 4.4 0.0079 16.4 0.0 3.1 2 2 1 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORX96372.1 - 1.3e-05 25.4 13.8 0.0035 17.7 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORX96372.1 - 0.0012 19.4 6.0 0.3 11.7 0.0 3.3 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORX96372.1 - 0.0016 19.1 17.0 0.05 14.5 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX96372.1 - 0.063 13.6 0.7 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon OrsD PF12013.8 ORX96372.1 - 0.52 10.8 3.3 17 5.9 0.2 3.1 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Metallophos PF00149.28 ORX96373.1 - 5.1e-40 138.2 0.1 8.1e-40 137.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX96373.1 - 9.2e-05 22.8 1.0 0.0002 21.7 1.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 ORX96373.1 - 0.054 13.7 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 ORX96373.1 - 0.068 12.8 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DHBP_synthase PF00926.19 ORX96374.1 - 2.7e-90 301.1 0.1 3.1e-90 300.9 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.7 ORX96375.1 - 4.5e-10 39.3 1.8 1.1e-09 38.0 1.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORX96375.1 - 0.00091 19.0 0.9 0.0036 17.1 0.2 2.4 2 0 0 2 2 2 1 F-box domain V-SNARE_C PF12352.8 ORX96376.1 - 1.1e-18 67.3 1.8 1.1e-18 67.3 1.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORX96376.1 - 6.2e-07 29.2 1.9 4.7e-06 26.4 0.0 2.4 1 1 0 2 2 2 1 Sec20 NDUF_C2 PF06374.11 ORX96376.1 - 0.032 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) WD40 PF00400.32 ORX96377.1 - 2.6e-43 145.2 22.4 2.8e-06 27.9 0.7 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX96377.1 - 6.2e-22 77.7 0.5 4.7e-09 36.4 0.0 6.1 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX96377.1 - 2.1e-09 37.5 2.0 0.036 14.0 0.0 4.3 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX96377.1 - 1e-07 31.6 0.1 4.7e-06 26.1 0.1 3.0 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 ORX96377.1 - 2.2e-05 24.0 0.1 0.28 10.5 0.0 4.2 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 ORX96377.1 - 7.8e-05 22.1 0.0 3.3 6.9 0.0 4.5 4 1 1 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 ORX96377.1 - 0.00012 20.9 0.2 0.0064 15.2 0.1 2.4 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DPPIV_N PF00930.21 ORX96377.1 - 0.00049 19.0 3.1 0.31 9.7 0.0 4.4 3 3 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ge1_WD40 PF16529.5 ORX96377.1 - 0.00056 19.0 1.0 2.4 7.0 0.0 4.6 3 2 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 ORX96377.1 - 0.0019 18.2 1.7 4.1 7.3 0.0 4.7 3 2 1 4 4 4 1 Transcription factor IIIC subunit delta N-term SGL PF08450.12 ORX96377.1 - 0.004 16.8 1.7 0.095 12.3 0.2 3.6 3 2 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 ORX96377.1 - 0.009 15.9 10.7 15 5.7 0.0 6.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 ORX96377.1 - 0.017 15.2 1.3 26 4.9 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ORX96377.1 - 0.017 14.2 0.3 0.59 9.1 0.1 2.4 2 0 0 2 2 2 0 Coatomer WD associated region DUF3642 PF12182.8 ORX96377.1 - 0.023 15.0 0.2 0.31 11.4 0.1 2.8 3 0 0 3 3 3 0 Bacterial lipoprotein DUF5122 PF17164.4 ORX96377.1 - 0.36 11.1 2.9 42 4.5 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller COX5B PF01215.19 ORX96378.1 - 1.3e-46 157.5 0.0 1.6e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Erg28 PF03694.13 ORX96379.1 - 1.6e-37 128.3 5.0 1.8e-37 128.1 5.0 1.0 1 0 0 1 1 1 1 Erg28 like protein FA_desaturase PF00487.24 ORX96379.1 - 0.11 12.4 6.0 0.12 12.1 6.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase zf-C2H2 PF00096.26 ORX96380.1 - 1.1e-07 31.9 5.9 0.0038 17.6 1.7 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96380.1 - 2e-05 25.0 3.8 0.17 12.8 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORX96380.1 - 0.015 15.9 1.3 0.4 11.3 0.1 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-CGNR PF11706.8 ORX96380.1 - 0.018 14.9 3.5 3.5 7.5 1.2 2.3 2 0 0 2 2 2 0 CGNR zinc finger zf-C2H2_11 PF16622.5 ORX96380.1 - 0.021 14.6 4.5 3.2 7.6 2.4 2.6 2 1 0 2 2 2 0 zinc-finger C2H2-type Lactamase_B PF00753.27 ORX96381.1 - 5.3e-19 69.0 0.0 9.3e-19 68.2 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX96381.1 - 0.00024 20.7 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CBAH PF02275.18 ORX96382.1 - 0.0095 15.6 0.2 0.013 15.2 0.2 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Kelch_5 PF13854.6 ORX96383.1 - 0.0056 16.6 0.3 2.1 8.5 0.0 2.4 2 0 0 2 2 2 2 Kelch motif RGS PF00615.19 ORX96394.1 - 6.3e-16 58.7 1.7 6.3e-16 58.7 1.7 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX96394.1 - 0.00046 20.0 13.9 0.0037 17.0 13.8 2.2 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR RGS-like PF09128.11 ORX96394.1 - 0.0015 18.3 0.1 0.0023 17.7 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain Ion_trans_2 PF07885.16 ORX96394.1 - 1.4 9.0 6.5 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Ion channel UPF0014 PF03649.13 ORX96395.1 - 2.3e-63 213.8 16.3 2.9e-63 213.5 16.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) TssN PF17555.2 ORX96395.1 - 4.2 6.7 10.9 0.33 10.3 4.1 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN LRR_4 PF12799.7 ORX96396.1 - 0.00028 21.2 7.7 0.045 14.2 0.2 5.7 5 3 2 7 7 7 2 Leucine Rich repeats (2 copies) RasGAP PF00616.19 ORX96397.1 - 2.5e-55 187.4 0.4 2.5e-55 187.4 0.4 3.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORX96397.1 - 2e-45 154.3 3.8 2e-45 154.3 3.8 4.5 5 1 0 5 5 5 1 RasGAP C-terminus IQ PF00612.27 ORX96397.1 - 8.3e-29 96.7 30.0 0.0075 16.0 0.0 10.6 10 0 0 10 10 10 9 IQ calmodulin-binding motif CH PF00307.31 ORX96397.1 - 3.5e-15 56.1 0.0 2.6e-14 53.3 0.0 2.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Noelin-1 PF12308.8 ORX96397.1 - 1.3 9.0 6.3 0.62 10.1 1.2 3.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein Pkinase PF00069.25 ORX96398.1 - 1.2e-57 195.3 0.0 1.4e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96398.1 - 5.1e-28 98.1 0.0 6.2e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX96398.1 - 2.7e-07 30.2 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX96398.1 - 5.1e-05 22.2 0.0 7.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX96398.1 - 0.0023 16.9 0.4 0.0029 16.6 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX96398.1 - 0.0061 16.5 0.2 0.0086 16.0 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX96398.1 - 0.018 14.4 0.5 0.026 13.9 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORX96399.1 - 1.5e-61 208.1 0.0 1.9e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96399.1 - 1e-29 103.6 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX96399.1 - 2.8e-10 40.0 0.0 4.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX96399.1 - 2.4e-05 23.3 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORX96399.1 - 0.013 14.5 0.3 0.018 14.0 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORX96399.1 - 0.015 15.2 0.3 0.027 14.4 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX96399.1 - 0.029 13.7 0.3 0.06 12.7 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX96399.1 - 0.096 12.3 0.4 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF5398 PF17376.2 ORX96399.1 - 0.15 12.7 3.0 0.19 12.3 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5398) dCMP_cyt_deam_1 PF00383.23 ORX96400.1 - 6.8e-13 48.4 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX96400.1 - 2.1e-10 40.5 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 ORX96400.1 - 0.0081 16.1 0.1 0.0087 16.0 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 ORX96400.1 - 0.014 15.5 0.2 0.024 14.8 0.2 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Inv-AAD PF18785.1 ORX96400.1 - 0.048 13.5 0.5 0.11 12.4 0.5 1.8 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase NAD1 PF18778.1 ORX96400.1 - 0.1 12.7 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 ORX96400.1 - 0.12 12.5 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 APOBEC2 Amidohydro_1 PF01979.20 ORX96401.1 - 2e-81 274.0 0.0 2.5e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX96401.1 - 1e-11 45.0 0.3 8.4e-09 35.4 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family PXA PF02194.15 ORX96402.1 - 3.9e-30 105.2 1.9 1.2e-29 103.5 1.2 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 ORX96402.1 - 4.8e-28 98.0 0.2 1.3e-27 96.6 0.2 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal RGS PF00615.19 ORX96402.1 - 4.9e-16 59.1 1.2 4.2e-15 56.1 0.7 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain PX PF00787.24 ORX96402.1 - 1.1e-11 44.7 0.2 2.9e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 PX domain C2 PF00168.30 ORX96402.1 - 6.8e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain Xpo1 PF08389.12 ORX96402.1 - 0.016 15.3 0.1 0.084 12.9 0.1 2.3 1 0 0 1 1 1 0 Exportin 1-like protein ABC_tran PF00005.27 ORX96403.1 - 2.2e-49 167.5 0.0 2.1e-28 99.6 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORX96403.1 - 3e-15 56.8 0.6 0.012 15.4 0.0 5.3 4 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX96403.1 - 3.2e-10 39.8 0.7 0.03 13.8 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain 4HB PF17947.1 ORX96403.1 - 6.9e-09 35.6 0.3 2.3e-08 34.0 0.3 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_23 PF13476.6 ORX96403.1 - 5.1e-08 33.7 0.0 0.012 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORX96403.1 - 4.4e-07 29.5 0.2 0.019 14.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 ORX96403.1 - 2.5e-06 27.3 0.1 5.6e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 ORX96403.1 - 1e-05 25.9 0.2 0.45 10.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 ORX96403.1 - 3.5e-05 23.8 0.4 0.073 13.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 ORX96403.1 - 7.8e-05 22.9 4.2 0.0023 18.0 0.0 3.3 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_16 PF13191.6 ORX96403.1 - 0.00011 22.6 0.6 0.11 12.8 0.0 3.6 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.12 ORX96403.1 - 0.00021 21.2 0.2 0.042 13.8 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_18 PF13238.6 ORX96403.1 - 0.00024 21.7 0.0 0.18 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX96403.1 - 0.00025 21.3 0.0 1.2 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ORX96403.1 - 0.00045 20.3 3.8 0.19 11.8 0.0 3.5 4 1 0 4 4 2 2 50S ribosome-binding GTPase AAA_27 PF13514.6 ORX96403.1 - 0.00048 19.8 0.0 0.91 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain HEAT_EZ PF13513.6 ORX96403.1 - 0.00085 19.8 4.1 2.3 8.8 0.1 5.3 3 2 2 5 5 4 1 HEAT-like repeat RNA_helicase PF00910.22 ORX96403.1 - 0.0012 19.2 0.0 3.2 8.2 0.0 2.9 2 0 0 2 2 2 1 RNA helicase HEAT_2 PF13646.6 ORX96403.1 - 0.0022 18.3 1.8 0.024 15.0 0.1 3.3 3 1 0 3 3 3 1 HEAT repeats AAA_33 PF13671.6 ORX96403.1 - 0.0028 17.8 0.1 2.4 8.3 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORX96403.1 - 0.0055 17.1 0.1 7.3 7.0 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Vac14_Fab1_bd PF12755.7 ORX96403.1 - 0.011 16.3 0.0 3.2 8.4 0.0 3.1 3 0 0 3 3 2 0 Vacuolar 14 Fab1-binding region Rad17 PF03215.15 ORX96403.1 - 0.011 15.7 0.3 0.77 9.7 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain MeaB PF03308.16 ORX96403.1 - 0.013 14.5 0.6 2.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORX96403.1 - 0.013 15.2 1.5 2.4 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 ORX96403.1 - 0.014 15.1 2.3 3 7.5 0.4 2.9 3 0 0 3 3 2 0 AAA ATPase domain AAA_7 PF12775.7 ORX96403.1 - 0.015 14.8 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORX96403.1 - 0.016 15.0 0.2 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORX96403.1 - 0.034 13.3 0.1 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 ORX96403.1 - 0.034 13.7 0.0 17 4.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 ORX96403.1 - 0.035 14.1 0.0 15 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 ORX96403.1 - 0.036 14.3 0.0 3.6 7.9 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 ORX96403.1 - 0.036 12.7 0.1 4 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.8 ORX96403.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 CLASP N terminal MukB PF04310.12 ORX96403.1 - 0.069 13.0 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Zeta_toxin PF06414.12 ORX96403.1 - 0.089 12.1 1.5 5.4 6.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin DUF3584 PF12128.8 ORX96403.1 - 0.1 10.1 1.4 1.4 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Roc PF08477.13 ORX96403.1 - 0.12 12.5 0.1 25 5.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORX96403.1 - 0.18 10.9 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 ORX96403.1 - 0.29 10.3 0.8 27 3.8 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Mpv17_PMP22 PF04117.12 ORX96404.1 - 1.4e-18 66.8 0.4 2.4e-18 66.1 0.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DPBB_1 PF03330.18 ORX96405.1 - 4.1e-22 78.2 0.0 1.8e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 Lytic transglycolase DUF2367 PF10164.9 ORX96405.1 - 0.0013 19.2 1.9 2.7 8.5 0.1 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2367) CCD PF07860.11 ORX96405.1 - 0.0077 16.3 8.1 0.22 11.6 0.7 2.6 2 1 0 2 2 2 2 WisP family C-Terminal Region Cerato-platanin PF07249.12 ORX96405.1 - 0.02 15.0 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Cerato-platanin CBM_14 PF01607.24 ORX96405.1 - 0.12 12.6 1.6 2.2 8.5 0.4 3.3 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain PADR1 PF08063.12 ORX96405.1 - 0.84 9.5 6.9 9 6.2 0.0 3.4 4 0 0 4 4 4 0 PADR1 (NUC008) domain SpoIIIAH PF12685.7 ORX96405.1 - 3.3 7.5 13.8 2.5 7.9 1.3 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein DPBB_1 PF03330.18 ORX96406.1 - 1.3e-09 38.2 1.4 2.7e-09 37.2 0.2 2.2 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 ORX96406.1 - 0.0053 16.6 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Barwin family CBM_14 PF01607.24 ORX96406.1 - 0.091 12.9 2.0 7.8 6.8 1.2 2.7 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain MG2 PF01835.19 ORX96407.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 MG2 domain GrpE PF01025.19 ORX96408.1 - 2.8e-36 124.7 0.8 3.4e-36 124.4 0.8 1.1 1 0 0 1 1 1 1 GrpE TerB_C PF15615.6 ORX96408.1 - 0.033 14.5 3.0 0.067 13.5 3.0 1.5 1 0 0 1 1 1 0 TerB-C domain TIP49_C PF17856.1 ORX96408.1 - 0.25 11.5 1.3 0.4 10.8 0.1 1.9 2 0 0 2 2 2 0 TIP49 AAA-lid domain RNA_pol_Rpb5_N PF03871.14 ORX96409.1 - 8.7e-34 116.0 0.2 1.7e-33 115.1 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 ORX96409.1 - 3.8e-33 113.2 0.1 8e-33 112.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 ORX96409.1 - 0.0028 17.7 0.0 0.022 14.8 0.0 2.1 1 1 1 2 2 2 1 Restriction endonuclease DUF4144 PF13642.6 ORX96409.1 - 0.037 14.6 0.1 4 8.1 0.0 2.2 2 0 0 2 2 2 0 protein structure with unknown function GATA PF00320.27 ORX96410.1 - 1e-29 101.8 16.1 2.2e-15 56.0 5.7 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORX96410.1 - 4e-12 45.7 2.4 1e-11 44.5 2.4 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 ORX96410.1 - 8.3e-08 31.6 4.0 0.0031 17.0 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX96410.1 - 9.3e-05 22.5 0.9 0.2 11.8 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORX96410.1 - 0.0043 17.2 5.3 0.38 11.0 0.8 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 ORX96410.1 - 0.036 14.1 7.1 1.4 9.0 8.0 2.8 1 1 2 3 3 3 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORX96410.1 - 0.09 12.7 5.1 1.6 8.7 0.5 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Limkain-b1 PF11608.8 ORX96410.1 - 0.1 12.7 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 Elf1 PF05129.13 ORX96410.1 - 0.19 11.8 3.8 2.5 8.2 0.1 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like FYVE PF01363.21 ORX96410.1 - 0.36 11.0 4.8 4.6 7.5 0.2 3.0 3 0 0 3 3 3 0 FYVE zinc finger eIF-5_eIF-2B PF01873.17 ORX96410.1 - 1.1 9.1 9.3 3.5 7.5 0.7 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 HypA PF01155.19 ORX96410.1 - 1.2 9.1 3.2 5.8 7.0 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 ORX96410.1 - 4.9 8.0 6.2 9.3 7.1 1.5 2.8 1 1 1 2 2 2 0 zinc-ribbon family FAM163 PF15069.6 ORX96410.1 - 6.1 7.3 9.9 0.83 10.1 0.7 3.5 2 2 1 3 3 3 0 FAM163 family DUF2462 PF09495.10 ORX96411.1 - 2.7e-17 63.3 10.4 2.7e-17 63.3 10.4 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) C1ORF64 PF15547.6 ORX96411.1 - 0.033 14.6 0.2 0.038 14.5 0.2 1.1 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein Pkinase PF00069.25 ORX96412.1 - 1.9e-64 217.6 0.0 2.3e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96412.1 - 1.5e-38 132.6 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX96412.1 - 3.6e-05 23.8 0.0 0.0073 16.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX96412.1 - 4e-05 23.1 0.0 0.00012 21.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX96412.1 - 9.8e-05 21.3 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORX96412.1 - 0.0029 16.7 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 ORX96412.1 - 0.004 16.5 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORX96412.1 - 0.077 11.9 0.1 0.66 8.8 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 ORX96412.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 ORX96412.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2 PF00096.26 ORX96413.1 - 4e-13 49.0 11.6 3.1e-06 27.3 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96413.1 - 2.3e-09 37.3 8.7 5.7e-05 23.6 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX96413.1 - 5.9e-06 26.5 1.7 5.9e-06 26.5 1.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX96413.1 - 0.00014 22.2 2.6 0.35 11.3 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX96413.1 - 0.00043 20.2 9.3 0.0005 20.0 0.3 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX96413.1 - 0.00071 19.3 9.8 0.075 12.8 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 ORX96413.1 - 0.0031 17.7 1.6 0.2 11.8 0.1 2.0 1 1 1 2 2 2 1 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORX96413.1 - 0.0049 17.1 3.4 0.21 11.9 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORX96413.1 - 0.0058 16.9 4.3 0.41 11.0 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 ORX96413.1 - 0.015 15.9 0.6 3.5 8.3 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX96413.1 - 0.023 15.0 0.4 0.075 13.3 0.4 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon CHORD PF04968.12 ORX96413.1 - 0.024 15.3 2.1 2.2 9.0 0.3 2.1 1 1 1 2 2 2 0 CHORD ADD_ATRX PF17981.1 ORX96413.1 - 0.062 13.2 2.5 0.64 9.9 0.1 2.0 1 1 1 2 2 2 0 Cysteine Rich ADD domain zf-C2HE PF16278.5 ORX96413.1 - 1.2 9.7 5.1 6.1 7.4 1.1 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger GPI-anchored PF10342.9 ORX96414.1 - 1.3e-10 41.8 0.1 2.3e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FLILHELTA PF10306.9 ORX96415.1 - 2.5e-12 47.0 0.0 4.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 ORX96415.1 - 0.018 15.5 0.1 0.037 14.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DUF3153 PF11353.8 ORX96415.1 - 0.091 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DAO PF01266.24 ORX96416.1 - 1.3e-58 199.3 0.1 1.5e-58 199.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX96416.1 - 0.00011 21.6 0.0 0.0092 15.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX96416.1 - 0.00028 20.9 0.1 1.9 8.5 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORX96416.1 - 0.00041 19.3 0.1 0.24 10.2 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 ORX96416.1 - 0.00076 19.7 1.8 0.067 13.4 0.9 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORX96416.1 - 0.0025 17.1 0.5 0.0037 16.5 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 ORX96416.1 - 0.027 13.5 0.1 4 6.4 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 ORX96416.1 - 0.047 14.2 0.2 0.098 13.2 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase VPS13 PF16908.5 ORX96417.1 - 1.1e-77 261.0 7.6 4.3e-76 255.8 2.2 3.4 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 ORX96417.1 - 3e-77 259.2 17.2 2.1e-74 249.9 1.8 4.8 4 1 0 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 ORX96417.1 - 1.5e-76 257.3 0.1 1.4e-72 244.3 0.0 2.9 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 ORX96417.1 - 6.7e-69 231.2 12.0 2.8e-64 216.2 1.5 3.5 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 ORX96417.1 - 1e-38 132.0 0.2 3.1e-38 130.5 0.2 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORX96417.1 - 3.8e-10 40.0 0.0 2.4e-08 34.2 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain L1R_F9L PF02442.17 ORX96417.1 - 0.22 11.4 0.8 19 5.1 0.1 2.6 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Cyclin PF08613.11 ORX96418.1 - 6e-09 36.5 0.3 1.2e-08 35.5 0.0 1.7 2 0 0 2 2 2 1 Cyclin ELL PF10390.9 ORX96418.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL S10_plectin PF03501.15 ORX96419.1 - 1.4e-47 159.7 0.1 1.6e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORX96419.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 ORX96419.1 - 0.085 12.9 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation Kinase-like PF14531.6 ORX96419.1 - 0.091 12.1 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF4364 PF14277.6 ORX96419.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2250 PF10007.9 ORX96419.1 - 0.2 11.8 1.0 4.3 7.5 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) PfkB PF00294.24 ORX96420.1 - 1e-40 140.0 0.0 1.5e-40 139.4 0.0 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GPI-anchored PF10342.9 ORX96421.1 - 1.7e-10 41.5 0.1 3e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dicty_CAR PF05462.11 ORX96422.1 - 3.4e-05 23.1 15.6 4.5e-05 22.7 15.6 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF1622 PF07784.11 ORX96422.1 - 0.015 15.2 0.6 0.07 13.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) Phage_holin_2_1 PF04971.12 ORX96422.1 - 0.038 14.0 2.1 3.7 7.6 0.1 3.0 2 1 0 2 2 2 0 Bacteriophage P21 holin S GPR_Gpa2_C PF11970.8 ORX96422.1 - 6.7 6.9 6.3 2.1 8.5 0.4 2.9 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Seipin PF06775.14 ORX96423.1 - 1.6e-51 175.3 3.7 2.3e-51 174.7 3.7 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) SWIRM PF04433.17 ORX96424.1 - 2.2e-10 40.7 0.6 7.2e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 ORX96424.1 - 6.3e-10 38.7 6.6 1.1e-09 38.0 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 ORX96424.1 - 7.1e-09 35.7 0.1 8.7e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX96424.1 - 0.0056 16.9 0.3 0.44 10.8 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain C1_2 PF03107.16 ORX96424.1 - 0.51 10.7 6.2 1 9.8 6.2 1.4 1 0 0 1 1 1 0 C1 domain Thioredoxin PF00085.20 ORX96443.1 - 7.2e-14 51.6 0.0 8.2e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORX96443.1 - 1.2e-05 25.5 0.1 1.3e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORX96443.1 - 0.028 14.9 0.0 0.029 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORX96443.1 - 0.04 14.1 0.1 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 ORX96443.1 - 0.049 13.5 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ORX96443.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Ribosomal_L27e PF01777.18 ORX96444.1 - 3.3e-36 123.5 7.7 3.3e-36 123.5 7.7 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 ORX96444.1 - 0.00013 21.8 1.4 0.00032 20.6 1.4 1.7 1 0 0 1 1 1 1 KOW motif NHR2 PF08788.11 ORX96446.1 - 0.1 12.3 0.5 0.16 11.7 0.5 1.3 1 0 0 1 1 1 0 NHR2 domain like Pkinase PF00069.25 ORX96447.1 - 2.1e-74 250.2 0.0 2.6e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96447.1 - 1.7e-31 109.5 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX96447.1 - 6.3e-09 35.6 0.0 1.3e-08 34.6 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORX96447.1 - 1.8e-05 23.8 0.4 4.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX96447.1 - 4.2e-05 23.6 0.4 0.0024 17.9 0.2 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX96447.1 - 6.9e-05 22.3 0.2 0.00011 21.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family STN1_2 PF09170.10 ORX96447.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 bZIP_2 PF07716.15 ORX96448.1 - 2.6e-07 30.6 14.9 5.5e-07 29.6 14.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX96448.1 - 6.2e-06 26.2 14.1 1.2e-05 25.3 14.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX96448.1 - 0.00021 21.7 10.9 0.00021 21.7 10.9 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor RNR_Alpha PF17975.1 ORX96449.1 - 1.8e-41 140.7 0.3 3.7e-41 139.7 0.3 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 ORX96449.1 - 1.2e-08 33.9 0.0 0.015 13.8 0.0 3.2 2 1 0 3 3 3 3 Ribonucleotide reductase, barrel domain zf-BED PF02892.15 ORX96449.1 - 0.0052 16.8 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 BED zinc finger zf-AN1 PF01428.16 ORX96450.1 - 1.2e-10 41.3 11.4 1.2e-10 41.3 11.4 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger IBR PF01485.21 ORX96450.1 - 0.24 11.7 12.6 1.1 9.6 12.6 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 ORX96450.1 - 0.37 10.9 10.9 5.3 7.1 10.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon Rhodanese_C PF12368.8 ORX96450.1 - 0.59 10.5 9.3 3 8.3 9.3 2.0 1 1 0 1 1 1 0 Rhodanase C-terminal UPF0547 PF10571.9 ORX96450.1 - 0.96 9.6 9.5 1.2 9.3 0.5 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.6 ORX96450.1 - 2.1 8.2 13.3 0.39 10.5 7.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain YacG PF03884.14 ORX96450.1 - 2.1 8.1 10.8 2.8 7.7 0.7 2.9 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-Tim10_DDP PF02953.15 ORX96451.1 - 0.42 10.3 6.6 2.6 7.8 2.6 2.7 2 1 1 3 3 3 0 Tim10/DDP family zinc finger Ribonuc_2-5A PF06479.12 ORX96452.1 - 3.9e-46 156.4 0.2 9.1e-46 155.2 0.1 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 ORX96452.1 - 1.1e-41 143.0 0.0 1.5e-30 106.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96452.1 - 8.8e-21 74.3 0.0 4.4e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX96452.1 - 1.4e-06 27.4 0.0 8.3e-06 24.8 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORX96452.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX96452.1 - 0.15 11.7 0.1 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Prenylcys_lyase PF07156.14 ORX96453.1 - 1.7e-49 168.9 0.0 2.2e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 ORX96453.1 - 7.7e-15 55.1 0.0 1.6e-14 54.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORX96453.1 - 3e-11 43.4 0.0 6.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX96453.1 - 1.3e-06 28.2 0.3 3.9e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORX96453.1 - 7.2e-05 22.1 0.0 0.027 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX96453.1 - 0.0001 22.3 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pkinase PF00069.25 ORX96454.1 - 5.4e-73 245.6 0.0 6.4e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96454.1 - 1.4e-35 122.9 0.0 1.7e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX96454.1 - 4.2e-08 32.8 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 ORX96454.1 - 0.00026 20.7 0.2 0.06 13.0 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX96454.1 - 0.13 11.1 0.2 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Chitin_synth_2 PF03142.15 ORX96455.1 - 1.3e-281 934.8 1.2 1.8e-281 934.3 1.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX96455.1 - 2.3e-15 57.1 0.0 5.3e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX96455.1 - 6e-14 52.4 3.7 2.2e-13 50.6 3.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX96455.1 - 3.9e-05 23.2 0.1 0.015 14.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX96455.1 - 0.0034 17.2 0.0 0.092 12.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF4229 PF14012.6 ORX96455.1 - 4.6 7.4 14.6 13 6.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) ADH_zinc_N PF00107.26 ORX96456.1 - 4e-14 52.7 0.0 6.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX96456.1 - 1.5e-13 52.0 0.0 2.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX96456.1 - 6.9e-09 35.6 0.0 3.6e-08 33.3 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ESM4 PF15952.5 ORX96472.1 - 6.6 7.1 5.6 5.3 7.5 2.1 2.1 1 1 1 2 2 2 0 Enhancer of split M4 family DUF3336 PF11815.8 ORX96473.1 - 1.9e-40 137.8 3.6 2.8e-40 137.2 3.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORX96473.1 - 3.7e-17 63.2 0.0 8.2e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Glyco_hydro_57 PF03065.15 ORX96473.1 - 0.018 14.2 0.4 0.026 13.7 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CNH PF00780.22 ORX96474.1 - 2.2e-55 188.2 0.0 3.5e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORX96474.1 - 5.5e-38 131.0 0.4 1.5e-37 129.6 0.4 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORX96474.1 - 1e-14 54.8 0.5 4.5e-08 33.3 0.0 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain DEP PF00610.21 ORX96474.1 - 3e-11 43.2 0.0 6.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 ORX96474.1 - 5e-06 26.4 0.0 2.6e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORX96474.1 - 4.4e-05 23.9 0.0 0.00017 22.1 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 ORX96474.1 - 0.14 12.0 0.4 0.94 9.3 0.4 2.3 1 1 0 1 1 1 0 PH domain Mito_carr PF00153.27 ORX96475.1 - 4.5e-67 222.0 3.0 4.8e-22 77.7 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX96475.1 - 0.089 11.9 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Gammaproteobacterial serine protease ABC1 PF03109.16 ORX96476.1 - 9.8e-31 106.4 0.0 1.7e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ORX96476.1 - 0.0031 17.5 0.1 0.054 13.4 0.1 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L35Ae PF01247.18 ORX96477.1 - 1.6e-45 153.2 0.8 1.8e-45 153.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORX96477.1 - 0.0039 17.4 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain MBOAT_2 PF13813.6 ORX96478.1 - 3.8e-11 43.1 1.8 9.9e-11 41.8 1.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short_C2 PF13561.6 ORX96479.1 - 2.6e-53 181.0 0.1 7.3e-53 179.5 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORX96479.1 - 4e-53 179.8 0.1 5.3e-53 179.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX96479.1 - 1.2e-08 35.1 0.3 2.1e-08 34.3 0.2 1.4 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 ORX96479.1 - 0.0085 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ORX96479.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Herpes_glycoH_C PF17488.2 ORX96479.1 - 0.051 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain GDP_Man_Dehyd PF16363.5 ORX96479.1 - 0.053 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Response_reg PF00072.24 ORX96481.1 - 4.4e-20 71.9 0.0 8.3e-20 71.0 0.0 1.4 1 1 0 1 1 1 1 Response regulator receiver domain FAD_binding_3 PF01494.19 ORX96482.1 - 2.7e-16 59.7 0.1 1.4e-06 27.8 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 ORX96482.1 - 5.3e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORX96482.1 - 0.0031 17.1 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 ORX96482.1 - 0.015 15.0 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ORX96482.1 - 0.031 13.5 0.0 0.081 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX96482.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORX96482.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain SinI PF08671.10 ORX96482.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Anti-repressor SinI Scs3p PF10261.9 ORX96483.1 - 3.3e-46 157.8 24.1 1.7e-35 122.7 10.5 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM CDP-OH_P_transf PF01066.21 ORX96484.1 - 1.4e-15 57.8 0.1 1.4e-15 57.8 0.1 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Hydrolase_4 PF12146.8 ORX96485.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CENP-C_C PF11699.8 ORX96486.1 - 1.9e-28 98.5 0.6 3.7e-28 97.6 0.6 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 ORX96486.1 - 1.8e-10 41.7 13.3 1.8e-10 41.7 13.3 3.5 1 1 1 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 ORX96486.1 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 ORX96486.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Peptidase_S28 PF05577.12 ORX96487.1 - 5.9e-79 265.9 0.0 7.3e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 ORX96487.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX96487.1 - 0.0087 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Dak1 PF02733.17 ORX96488.1 - 1.4e-109 365.8 5.0 1.8e-109 365.4 5.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ORX96488.1 - 2.5e-44 151.3 0.0 6.1e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 DAK2 domain adh_short PF00106.25 ORX96489.1 - 2.1e-46 157.9 0.0 2.5e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX96489.1 - 5.8e-34 117.7 0.0 7e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX96489.1 - 2.3e-08 34.2 0.0 3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORX96489.1 - 0.008 16.1 0.3 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RE_Eco47II PF09553.10 ORX96489.1 - 0.025 14.1 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 Eco47II restriction endonuclease Epimerase PF01370.21 ORX96489.1 - 0.03 13.8 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 ORX96489.1 - 0.033 13.8 0.1 0.095 12.3 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster4 family ATP_bind_2 PF03668.15 ORX96489.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Peptidase_S21 PF00716.17 ORX96489.1 - 0.043 13.5 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Baculo_ME53 PF06061.11 ORX96489.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 Methyltransf_11 PF08241.12 ORX96489.1 - 0.087 13.5 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 ORX96490.1 - 9e-95 317.7 0.0 1.4e-94 317.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 ORX96490.1 - 4.2e-08 32.6 5.2 0.038 13.7 0.0 6.0 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 ORX96490.1 - 9.9e-06 25.8 0.0 2.9e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 ORX96490.1 - 1.3e-05 24.9 8.4 0.0051 16.5 0.1 5.3 4 1 1 5 5 5 1 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.6 ORX96490.1 - 1.7e-05 25.7 0.1 3.9e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_16 PF00722.21 ORX96493.1 - 7.2e-32 110.3 5.4 1.2e-31 109.6 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CitMHS PF03600.16 ORX96517.1 - 1.7e-23 83.3 46.7 1.1e-19 70.8 25.3 2.1 1 1 1 2 2 2 2 Citrate transporter FAM75 PF14650.6 ORX96517.1 - 1.7 8.1 3.4 2.4 7.6 3.4 1.1 1 0 0 1 1 1 0 FAM75 family G-alpha PF00503.20 ORX96519.1 - 5.5e-121 404.0 5.0 7.4e-121 403.6 5.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Bestrophin PF01062.21 ORX96519.1 - 7.5e-51 173.3 0.1 1.5e-50 172.3 0.1 1.4 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Arf PF00025.21 ORX96519.1 - 4e-15 55.7 0.4 2.5e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORX96519.1 - 0.00048 19.9 0.1 0.0017 18.2 0.1 1.9 1 0 0 1 1 1 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORX96519.1 - 0.0018 17.6 0.2 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORX96519.1 - 0.011 15.7 0.2 1 9.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX96519.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORX96519.1 - 0.09 13.0 0.1 6.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORX96519.1 - 0.12 11.9 0.1 1.1 8.7 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arrestin_C PF02752.22 ORX96520.1 - 5.9e-08 33.3 0.1 8.7e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX96520.1 - 6.1e-07 29.6 0.0 1.8e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX96520.1 - 0.0063 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Velvet PF11754.8 ORX96521.1 - 1.1e-73 248.2 0.1 2.2e-44 152.3 0.0 2.2 1 1 1 2 2 2 2 Velvet factor CsbD PF05532.12 ORX96522.1 - 0.11 12.4 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 CsbD-like DUF4677 PF15726.5 ORX96523.1 - 0.11 12.6 1.5 0.21 11.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4677) HMG_box PF00505.19 ORX96524.1 - 8e-23 80.6 1.8 1.1e-22 80.2 1.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX96524.1 - 4.3e-11 43.3 0.7 6e-11 42.8 0.7 1.2 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 ORX96524.1 - 0.014 15.6 0.3 0.017 15.3 0.3 1.2 1 0 0 1 1 1 0 Protamine and protamine like HTH_24 PF13412.6 ORX96524.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MATalpha_HMGbox PF04769.12 ORX96524.1 - 0.043 13.1 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Ntox43 PF15537.6 ORX96524.1 - 0.081 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 43 Histone PF00125.24 ORX96525.1 - 1.5e-44 151.5 2.3 1.9e-44 151.2 2.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX96525.1 - 1.1e-05 25.7 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORX96525.1 - 4.8e-05 23.4 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 ORX96525.1 - 0.041 14.0 0.4 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit UCH PF00443.29 ORX96526.1 - 4.8e-79 265.5 0.1 6.5e-79 265.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX96526.1 - 1.2e-15 58.0 0.2 3e-08 33.6 0.1 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORX96526.1 - 2.5e-15 56.9 1.6 5.6e-15 55.7 0.4 2.3 2 0 0 2 2 2 1 DUSP domain USP7_C2 PF14533.6 ORX96526.1 - 4.4e-05 23.3 0.1 0.0047 16.7 0.0 3.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal zf-ribbon_3 PF13248.6 ORX96526.1 - 0.51 9.8 2.2 23 4.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Oxysterol_BP PF01237.18 ORX96527.1 - 2.5e-103 345.8 1.2 4.4e-103 345.0 1.2 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 ORX96527.1 - 1.5e-16 60.3 2.2 2.2e-07 31.0 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORX96527.1 - 2.5e-13 50.4 0.0 1.2e-06 29.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX96527.1 - 2.4e-12 45.9 0.3 0.00066 19.9 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 ORX96527.1 - 3.4e-11 43.6 1.0 8.5e-10 39.1 0.0 2.7 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 ORX96527.1 - 1.6e-10 41.3 0.1 1.7e-05 25.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORX96527.1 - 2.5e-10 40.3 0.1 0.0011 19.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 ORX96527.1 - 7.1e-08 32.6 0.2 2e-07 31.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 ORX96527.1 - 0.002 18.5 1.1 0.002 18.5 1.1 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain Cullin PF00888.22 ORX96529.1 - 8.6e-159 530.0 16.6 1.3e-158 529.4 16.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORX96529.1 - 3.2e-27 94.4 2.6 3.2e-27 94.4 2.6 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain bZIP_1 PF00170.21 ORX96530.1 - 1.9e-12 47.1 7.7 2.8e-12 46.6 7.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORX96530.1 - 9.3e-07 28.8 7.7 2.2e-06 27.7 7.7 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORX96530.1 - 0.00014 22.3 5.4 0.00019 21.9 5.4 1.3 1 1 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 ORX96530.1 - 0.0073 16.5 0.9 0.0073 16.5 0.9 1.9 2 1 0 2 2 2 1 Homeobox associated leucine zipper GIT_CC PF16559.5 ORX96530.1 - 0.11 12.4 2.8 0.18 11.7 2.8 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1308 PF07000.11 ORX96531.1 - 1.2e-24 87.2 0.0 1.2e-16 61.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) DUF5614 PF18474.1 ORX96531.1 - 1.5e-12 47.3 0.0 6.5e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5614) SAWADEE PF16719.5 ORX96532.1 - 0.14 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 SAWADEE domain GPI-anchored PF10342.9 ORX96533.1 - 2.8e-15 56.8 0.9 4.9e-15 56.1 0.9 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cytomega_UL20A PF05984.12 ORX96533.1 - 0.06 13.6 0.2 0.06 13.6 0.2 2.1 2 1 0 2 2 2 0 Cytomegalovirus UL20A protein GPI-anchored PF10342.9 ORX96534.1 - 8.3e-13 48.9 0.0 8.3e-13 48.9 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 ORX96534.1 - 0.023 13.9 12.9 0.025 13.8 12.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 ORX96534.1 - 0.47 10.3 5.8 0.48 10.3 5.8 1.1 1 0 0 1 1 1 0 SPX domain GPI-anchored PF10342.9 ORX96535.1 - 1.3e-14 54.7 0.1 2.2e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M20 PF01546.28 ORX96536.1 - 2.3e-36 125.4 0.0 3.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORX96536.1 - 1.3e-12 47.6 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORX96536.1 - 1.8e-06 27.8 0.0 0.00011 22.0 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ORX96536.1 - 0.091 11.8 0.0 14 4.5 0.0 3.3 4 0 0 4 4 4 0 M42 glutamyl aminopeptidase Zn_clus PF00172.18 ORX96537.1 - 2.6e-07 30.7 17.3 4.5e-07 29.9 17.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORX96537.1 - 9.3e-06 24.9 0.7 1.7e-05 24.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vir_act_alpha_C PF10400.9 ORX96561.1 - 0.009 16.7 1.2 1.8 9.3 0.1 2.1 2 0 0 2 2 2 2 Virulence activator alpha C-term Prefoldin_2 PF01920.20 ORX96561.1 - 0.09 12.7 2.3 0.67 9.9 0.5 2.0 2 0 0 2 2 2 0 Prefoldin subunit Trp_syntA PF00290.20 ORX96562.1 - 5.2e-94 313.9 0.0 8.3e-94 313.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 ORX96562.1 - 7.7e-48 163.4 2.1 1.4e-47 162.6 0.7 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 ORX96562.1 - 0.076 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein WD40 PF00400.32 ORX96563.1 - 1.5e-67 221.8 28.2 8.6e-10 39.1 0.5 9.3 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX96563.1 - 4.6e-26 90.9 0.8 1.2e-06 28.8 0.0 5.6 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX96563.1 - 4.5e-12 46.2 0.1 0.0019 18.1 0.0 4.1 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX96563.1 - 7.8e-12 44.8 0.1 0.0033 16.4 0.0 5.1 3 3 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX96563.1 - 2.2e-06 26.6 1.9 3.8 6.0 0.0 5.4 3 3 2 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORX96563.1 - 3.4e-06 26.6 1.6 0.18 11.1 0.0 4.7 3 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal NLE PF08154.12 ORX96563.1 - 2.4e-05 24.8 0.0 0.00022 21.7 0.0 2.3 1 1 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 ORX96563.1 - 2.7e-05 23.7 0.0 1.4 8.1 0.0 3.7 4 0 0 4 4 4 2 WD40-like domain PD40 PF07676.12 ORX96563.1 - 0.00032 20.5 5.7 0.88 9.6 0.1 4.6 5 0 0 5 5 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 ORX96563.1 - 0.00077 18.1 0.0 0.053 12.0 0.0 3.1 3 1 0 3 3 3 1 Cytochrome D1 heme domain Frtz PF11768.8 ORX96563.1 - 0.0027 16.1 0.0 0.59 8.4 0.0 2.5 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 ORX96563.1 - 0.0035 17.0 0.7 4.5 7.1 0.0 4.4 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature IKI3 PF04762.12 ORX96563.1 - 0.073 11.1 0.1 0.18 9.7 0.1 1.6 2 0 0 2 2 2 0 IKI3 family PP2C PF00481.21 ORX96564.1 - 3.1e-64 217.1 0.0 5e-64 216.4 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_S13_N PF08069.12 ORX96565.1 - 8.1e-32 109.1 0.1 1.5e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORX96565.1 - 4e-14 52.6 0.4 5.9e-14 52.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 ORX96565.1 - 0.07 13.1 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HTH_32 PF13565.6 ORX96565.1 - 0.075 13.7 0.2 0.17 12.5 0.0 1.7 2 1 0 2 2 2 0 Homeodomain-like domain CHCH PF06747.13 ORX96567.1 - 8.2e-09 35.4 3.1 1.6e-08 34.5 3.1 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 ORX96567.1 - 0.00056 20.3 4.9 0.00093 19.6 4.9 1.5 1 0 0 1 1 1 1 GCK domain Voldacs PF03517.13 ORX96567.1 - 2.7 8.1 15.4 7.8 6.6 15.4 1.8 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling PBP1_TM PF14812.6 ORX96567.1 - 3 8.3 8.9 0.85 10.0 6.2 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PIP5K PF01504.18 ORX96568.1 - 1.1e-97 326.6 0.1 1.5e-97 326.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ATP-synt_G PF04718.15 ORX96569.1 - 2e-19 70.2 1.9 2.7e-19 69.8 0.7 1.8 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit I_LWEQ PF01608.17 ORX96569.1 - 0.0098 16.1 2.1 0.012 15.9 2.1 1.2 1 0 0 1 1 1 1 I/LWEQ domain RuvA_C PF07499.13 ORX96569.1 - 0.14 12.7 0.1 0.14 12.7 0.1 2.6 3 0 0 3 3 3 0 RuvA, C-terminal domain eIF3g PF12353.8 ORX96570.1 - 9e-42 142.4 0.6 1.5e-41 141.7 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 ORX96570.1 - 4.1e-17 61.8 0.0 8.6e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX96570.1 - 0.012 15.4 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 Occluded RNA-recognition motif MoaE PF02391.17 ORX96571.1 - 1.4e-25 89.8 0.2 1.6e-25 89.6 0.2 1.0 1 0 0 1 1 1 1 MoaE protein Herpes_gE PF02480.16 ORX96572.1 - 0.01 14.6 0.3 0.013 14.3 0.3 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 ORX96572.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Phage_holin_2_4 PF16082.5 ORX96572.1 - 0.029 14.1 0.2 0.066 13.0 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Amnionless PF14828.6 ORX96572.1 - 0.034 13.0 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless Protocadherin PF08374.11 ORX96572.1 - 0.048 13.6 0.0 0.09 12.7 0.0 1.3 1 1 0 1 1 1 0 Protocadherin Syndecan PF01034.20 ORX96572.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 ORX96572.1 - 0.087 13.2 0.6 0.087 13.2 0.6 1.7 2 0 0 2 2 1 0 FeoB-associated Cys-rich membrane protein DUF3318 PF11780.8 ORX96572.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) PgaD PF13994.6 ORX96572.1 - 0.13 12.3 0.2 0.21 11.7 0.1 1.4 1 1 0 1 1 1 0 PgaD-like protein ETRAMP PF09716.10 ORX96572.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAPT PF11770.8 ORX96572.1 - 0.45 10.4 1.7 16 5.3 0.1 2.2 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) WD40 PF00400.32 ORX96573.1 - 1.1e-48 162.2 38.0 1.9e-09 37.9 0.4 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.8 ORX96573.1 - 2.6e-13 49.5 10.0 0.039 12.6 0.1 5.7 2 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.7 ORX96573.1 - 5.6e-12 45.4 0.1 1.6e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORX96573.1 - 1.4e-08 34.9 4.7 0.27 11.6 0.1 6.1 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX96573.1 - 2.1e-07 30.7 0.1 7.2e-07 28.9 0.2 1.9 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 ORX96573.1 - 8.6e-05 22.0 0.7 0.00024 20.5 0.2 1.8 2 0 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 ORX96573.1 - 0.00017 21.6 0.5 4.1 7.5 0.0 4.5 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 ORX96573.1 - 0.0026 17.6 0.1 0.2 11.6 0.0 3.1 2 1 0 2 2 2 1 F-box AsnC_trans_reg PF01037.21 ORX96573.1 - 0.026 14.5 0.1 39 4.3 0.0 3.7 4 0 0 4 4 4 0 Lrp/AsnC ligand binding domain eIF2A PF08662.11 ORX96573.1 - 0.13 12.1 0.3 0.85 9.5 0.1 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-C2H2 PF00096.26 ORX96574.1 - 1.8e-11 43.8 15.5 6.9e-06 26.2 0.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX96574.1 - 7.2e-11 42.0 8.2 9.5e-11 41.6 0.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX96574.1 - 5.6e-10 39.2 11.7 5.5e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96574.1 - 1.3e-06 28.6 3.1 0.0065 16.7 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX96574.1 - 8.4e-05 22.8 3.1 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX96574.1 - 0.00016 21.5 3.4 0.00088 19.2 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX96574.1 - 0.00026 20.7 8.0 0.0051 16.5 0.0 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type PyrI_C PF02748.15 ORX96574.1 - 0.0019 18.1 0.3 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2256 PF10013.9 ORX96574.1 - 0.0022 18.1 2.2 0.033 14.3 0.3 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 ORX96574.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.2 2 1 0 2 2 1 1 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 ORX96574.1 - 0.008 16.1 0.3 3.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-C2H2_2 PF12756.7 ORX96574.1 - 0.013 15.8 4.0 2.1 8.7 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORX96574.1 - 0.014 15.4 4.9 0.14 12.2 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 ORX96574.1 - 0.027 14.6 3.7 0.3 11.2 0.5 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-MYST PF17772.1 ORX96574.1 - 0.031 13.9 3.7 1.9 8.2 1.3 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf_ZIC PF18366.1 ORX96574.1 - 0.057 13.5 3.1 1.5 9.0 1.2 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain C5HCH PF17982.1 ORX96574.1 - 0.12 12.5 6.1 0.89 9.8 2.6 2.1 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2HE PF16278.5 ORX96574.1 - 0.66 10.5 6.1 1.5 9.3 0.2 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Acyltransferase PF01553.21 ORX96575.1 - 2.5e-08 33.6 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L2 PF00181.23 ORX96575.1 - 0.15 12.1 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain Molybdopterin PF00384.22 ORX96576.1 - 1.1e-70 238.9 0.0 7.5e-70 236.0 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ORX96576.1 - 2.6e-19 69.1 0.0 5.7e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ORX96576.1 - 5.1e-17 61.1 0.1 5.1e-17 61.1 0.1 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 ORX96576.1 - 6.7e-16 58.7 0.3 1.6e-15 57.5 0.3 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 ORX96576.1 - 6.2e-09 35.7 2.0 9.8e-09 35.0 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ORX96576.1 - 0.00031 20.5 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 ORX96576.1 - 0.09 12.6 1.1 4.7 7.2 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain CIA30 PF08547.12 ORX96577.1 - 1.1e-31 110.1 0.0 1.3e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Metallophos PF00149.28 ORX96578.1 - 7e-37 127.9 0.1 9.6e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX96578.1 - 6.6e-17 61.7 0.0 2.2e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PMT PF02366.18 ORX96579.1 - 1.9e-81 273.3 18.3 1.9e-81 273.3 18.3 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX96579.1 - 3.7e-66 222.5 12.4 3.7e-66 222.5 12.4 2.5 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX96579.1 - 3.3e-30 105.3 2.2 5.4e-30 104.6 2.2 1.2 1 0 0 1 1 1 1 MIR domain Mucin_bdg PF03272.13 ORX96579.1 - 0.29 11.2 0.8 0.92 9.6 0.9 1.7 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module VHS PF00790.19 ORX96580.1 - 3.3e-35 121.0 1.2 6.9e-35 119.9 1.2 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 ORX96580.1 - 7.1e-16 57.5 0.1 1.6e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX96580.1 - 3.5e-12 46.0 0.1 9.8e-12 44.6 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX96580.1 - 1e-11 44.3 0.2 2.5e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 ORX96580.1 - 1.9e-05 24.9 0.1 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 ORX96580.1 - 0.0005 19.8 3.1 0.0017 18.1 3.1 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF3900 PF13039.6 ORX96580.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3900) ATP_synt_H PF05493.13 ORX96581.1 - 2.9e-25 88.5 2.2 3.4e-25 88.3 2.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 ORX96581.1 - 0.013 15.2 0.9 0.014 15.0 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MtrC PF04211.13 ORX96581.1 - 0.051 12.6 0.8 0.059 12.4 0.8 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Flavi_NS4A PF01350.17 ORX96581.1 - 0.083 12.8 0.4 0.1 12.6 0.4 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Popeye PF04831.13 ORX96581.1 - 0.12 12.6 1.6 0.14 12.3 1.6 1.1 1 0 0 1 1 1 0 Popeye protein conserved region OppC_N PF12911.7 ORX96581.1 - 0.35 10.9 8.2 2.7 8.1 0.8 2.1 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF997 PF06196.12 ORX96581.1 - 2.6 8.1 7.5 2.3 8.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF997) FeoB_associated PF12669.7 ORX96581.1 - 4.9 7.6 8.6 7.4 7.1 0.5 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Tyrosinase PF00264.20 ORX96582.1 - 5.8e-10 39.8 0.1 6.4e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Ploopntkinase1 PF18748.1 ORX96582.1 - 0.053 13.0 0.0 1.9 8.0 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 CTP_transf_like PF01467.26 ORX96583.1 - 1.1e-44 152.0 0.3 4.8e-26 91.7 0.0 2.6 3 0 0 3 3 3 2 Cytidylyltransferase-like FAD_syn PF06574.12 ORX96583.1 - 6.1e-05 23.0 0.1 0.23 11.4 0.0 2.8 3 0 0 3 3 3 2 FAD synthetase DUF4121 PF13497.6 ORX96583.1 - 0.094 11.9 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) GFD1 PF17331.2 ORX96583.1 - 6.4 7.1 6.5 1.3 9.3 2.4 1.9 2 0 0 2 2 2 0 GFD1 mRNA transport factor Ank_2 PF12796.7 ORX96607.1 - 2.1e-26 92.3 0.9 1.3e-12 48.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORX96607.1 - 7.3e-21 74.3 3.6 1.9e-08 34.7 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORX96607.1 - 6.9e-20 70.9 0.2 2.1e-09 37.4 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORX96607.1 - 2e-14 53.3 0.1 0.0011 19.3 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 ORX96607.1 - 1.7e-11 43.2 0.2 0.0098 16.3 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Kelch_1 PF01344.25 ORX96608.1 - 1.6e-24 85.2 3.9 1.3e-05 24.7 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 ORX96608.1 - 1e-23 83.1 11.0 7.3e-07 29.1 0.0 5.6 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORX96608.1 - 2.8e-23 81.4 11.6 3.2e-05 24.1 0.2 6.1 4 2 2 6 6 6 4 Kelch motif Kelch_5 PF13854.6 ORX96608.1 - 1.1e-22 79.5 4.6 8.6e-06 25.6 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 ORX96608.1 - 1.6e-19 69.0 9.4 1e-07 31.6 0.1 6.3 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORX96608.1 - 2.8e-19 68.9 6.2 5e-06 26.7 0.0 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 ORX96608.1 - 1.7e-16 60.4 0.1 3.6e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Dynein_light PF01221.18 ORX96609.1 - 2.9e-41 139.7 1.8 3.2e-41 139.5 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4901 PF16244.5 ORX96609.1 - 0.056 12.8 0.7 0.065 12.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) Ectatomin PF06457.11 ORX96609.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Ectatomin Cnd2 PF05786.14 ORX96610.1 - 2.9e-134 449.5 5.1 2.5e-75 254.6 0.1 3.3 1 1 2 3 3 3 3 Condensin complex subunit 2 CNDH2_C PF16858.5 ORX96610.1 - 0.069 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rft-1 PF04506.13 ORX96611.1 - 4.7e-139 464.4 12.3 5.4e-139 464.2 12.3 1.0 1 0 0 1 1 1 1 Rft protein GCD14 PF08704.10 ORX96613.1 - 2.6e-98 328.6 0.0 3.4e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 ORX96613.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORX96613.1 - 0.00035 20.4 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ORX96613.1 - 0.076 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 ORX96613.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DUF2335 PF10097.9 ORX96614.1 - 0.22 11.5 5.2 2.1 8.3 2.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) NAD_binding_10 PF13460.6 ORX96615.1 - 6e-29 101.2 0.0 7e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX96615.1 - 3e-07 30.2 1.1 6.4e-07 29.2 0.2 2.0 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.21 ORX96615.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORX96615.1 - 0.0035 16.8 0.5 0.0052 16.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 ORX96615.1 - 0.0091 15.0 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.15 ORX96615.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus GDP_Man_Dehyd PF16363.5 ORX96615.1 - 0.027 13.8 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PMSR PF01625.21 ORX96616.1 - 2.5e-63 212.8 4.3 2.9e-63 212.6 4.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase NopRA1 PF16201.5 ORX96616.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 p450 PF00067.22 ORX96617.1 - 7.6e-79 265.6 0.0 9.9e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GDA1_CD39 PF01150.17 ORX96619.1 - 2.9e-118 395.2 0.0 4e-118 394.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 ORX96619.1 - 0.0045 16.5 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Sarcoglycan_1 PF04790.13 ORX96619.1 - 0.14 11.5 0.8 0.24 10.7 0.8 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Ecl1 PF12855.7 ORX96620.1 - 2.4e-09 38.6 0.5 3.1e-09 38.3 0.5 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 ORX96620.1 - 0.14 12.2 0.7 0.25 11.3 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Fasciclin PF02469.22 ORX96621.1 - 1.4e-45 154.7 10.2 1.1e-26 93.5 2.5 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 ORX96621.1 - 0.93 9.7 4.3 13 6.0 1.4 3.0 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 Cyclin_N PF00134.23 ORX96622.1 - 4e-09 36.3 0.0 5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX96622.1 - 1e-06 29.2 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin zf-H2C2_2 PF13465.6 ORX96623.1 - 2.8e-15 56.0 18.8 4.6e-08 33.1 1.7 3.4 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX96623.1 - 2.2e-14 53.0 16.6 1.6e-05 25.0 3.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96623.1 - 1.9e-11 43.8 13.8 0.0021 18.8 2.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX96623.1 - 1e-07 31.8 16.1 0.00044 20.2 0.3 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96623.1 - 4.3e-06 26.9 6.4 0.17 12.2 0.0 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORX96623.1 - 0.00041 20.0 1.6 0.00041 20.0 1.6 3.2 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf_ZIC PF18366.1 ORX96623.1 - 0.00074 19.6 2.2 5.8 7.1 0.0 3.2 2 1 1 3 3 3 2 Zic proteins zinc finger domain zf-C2HE PF16278.5 ORX96623.1 - 0.0067 16.9 12.3 0.077 13.5 4.2 2.9 1 1 2 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORX96623.1 - 0.0081 15.9 5.2 0.17 11.7 0.1 2.6 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 ORX96623.1 - 0.0088 16.3 5.7 0.0097 16.2 2.3 1.9 1 1 1 2 2 2 1 C2H2-type zinc ribbon IBR PF01485.21 ORX96623.1 - 0.013 15.8 0.7 0.013 15.8 0.7 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_3rep PF18868.1 ORX96623.1 - 0.017 15.8 5.5 0.33 11.6 5.1 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 ORX96623.1 - 0.021 15.0 9.0 0.43 10.7 0.7 3.1 3 0 0 3 3 3 0 Zinc ribbon domain BolA PF01722.18 ORX96623.1 - 0.043 14.1 0.6 2.7 8.3 0.2 2.1 1 1 1 2 2 2 0 BolA-like protein zf-AN1 PF01428.16 ORX96623.1 - 0.39 10.9 13.8 2.5 8.3 3.9 3.1 2 1 1 3 3 3 0 AN1-like Zinc finger PyrI_C PF02748.15 ORX96623.1 - 0.46 10.4 7.3 14 5.7 0.2 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 ORX96623.1 - 0.81 10.2 7.2 1.4 9.4 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 ORX96623.1 - 1.5 8.9 9.9 5.5 7.0 3.1 2.8 1 1 2 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.12 ORX96623.1 - 2.5 8.4 10.4 1.5 9.1 1.4 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain Ribosomal_S5 PF00333.20 ORX96624.1 - 2.2e-16 59.6 0.0 3.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX96624.1 - 7.8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF155 PF02582.14 ORX96625.1 - 2.5e-52 177.5 0.9 4.2e-52 176.8 0.2 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 bZIP_2 PF07716.15 ORX96626.1 - 5.4e-11 42.4 13.5 8.2e-11 41.8 13.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX96626.1 - 0.001 19.1 9.5 0.0017 18.4 9.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor Ax_dynein_light PF10211.9 ORX96626.1 - 0.014 15.4 1.1 0.019 14.9 1.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain XhlA PF10779.9 ORX96626.1 - 0.068 13.4 3.8 0.1 12.8 3.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA CREPT PF16566.5 ORX96626.1 - 0.11 12.6 3.1 0.19 11.9 3.1 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Herpes_UL25 PF01499.16 ORX96626.1 - 0.12 10.9 1.5 0.16 10.4 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family HI0933_like PF03486.14 ORX96626.1 - 0.23 10.1 0.6 0.32 9.7 0.6 1.1 1 0 0 1 1 1 0 HI0933-like protein HMG_box PF00505.19 ORX96627.1 - 1.3e-14 54.3 1.0 1.3e-14 54.3 1.0 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 ORX96627.1 - 2.8e-13 50.1 0.1 5.1e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORX96627.1 - 5.8e-10 39.1 0.1 1.2e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 ORX96627.1 - 7.4e-10 39.3 2.7 1.3e-09 38.5 1.6 2.0 1 1 0 1 1 1 1 HMG-box domain Phe_tRNA-synt_N PF02912.18 ORX96627.1 - 0.004 17.0 0.1 0.0078 16.1 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain Complex1_LYR_2 PF13233.6 ORX96627.1 - 0.0053 17.5 0.5 0.013 16.2 0.5 1.6 1 0 0 1 1 1 1 Complex1_LYR-like WYL_3 PF18488.1 ORX96627.1 - 0.013 15.8 1.4 0.027 14.8 1.4 1.4 1 0 0 1 1 1 0 WYL domain MlaC PF05494.12 ORX96627.1 - 0.033 13.9 0.2 0.053 13.3 0.2 1.3 1 0 0 1 1 1 0 MlaC protein RIB43A PF05914.12 ORX96627.1 - 0.075 11.8 1.2 0.094 11.4 1.2 1.1 1 0 0 1 1 1 0 RIB43A IGR PF09597.10 ORX96627.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 IGR protein motif NCD1 PF04904.13 ORX96627.1 - 0.11 12.5 0.1 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) GATA PF00320.27 ORX96629.1 - 4.2e-14 51.8 6.0 8.4e-14 50.9 6.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 ORX96629.1 - 2.7e-11 43.4 0.0 5.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ORX96629.1 - 1.4e-08 34.9 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORX96629.1 - 1.9e-08 34.5 0.0 5.5e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 ORX96629.1 - 1.6e-05 25.0 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORX96629.1 - 7.9e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold ZapB PF06005.12 ORX96629.1 - 0.025 15.0 0.1 0.07 13.6 0.1 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DZR PF12773.7 ORX96629.1 - 0.075 13.1 0.6 0.38 10.8 0.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 ORX96629.1 - 0.076 12.5 0.6 0.94 9.0 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORX96629.1 - 0.09 12.9 0.7 0.21 11.7 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AcylCoA_DH_N PF12418.8 ORX96629.1 - 0.11 12.5 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal zf-NADH-PPase PF09297.11 ORX96629.1 - 2.1 8.0 5.7 2 8.1 0.1 2.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-MYND PF01753.18 ORX96629.1 - 2.9 8.1 6.9 1.2 9.3 0.2 2.5 2 1 0 2 2 2 0 MYND finger ADP_PFK_GK PF04587.15 ORX96630.1 - 0.057 12.0 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Chitin_synth_1 PF01644.17 ORX96631.1 - 4.4e-75 251.1 0.5 6.9e-75 250.5 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORX96631.1 - 1.4e-29 101.9 0.1 2.8e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORX96631.1 - 2.3e-27 95.8 1.7 1.9e-21 76.3 0.0 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORX96631.1 - 3.5e-09 36.9 0.4 3.5e-09 36.9 0.4 3.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORX96631.1 - 0.003 17.5 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORX96631.1 - 0.093 12.2 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 SNARE_assoc PF09335.11 ORX96632.1 - 2.5e-11 44.1 1.0 1.5e-08 35.1 0.2 3.1 3 0 0 3 3 3 2 SNARE associated Golgi protein PelG PF16933.5 ORX96632.1 - 0.0063 15.4 0.7 0.0063 15.4 0.7 2.0 2 0 0 2 2 2 1 Putative exopolysaccharide Exporter (EPS-E) PS_Dcarbxylase PF02666.15 ORX96632.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 Phosphatidylserine decarboxylase SelR PF01641.18 ORX96633.1 - 8.9e-54 180.7 0.1 1e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 ORX96633.1 - 0.0081 15.9 1.1 0.8 9.5 0.0 2.2 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 ORX96633.1 - 0.031 14.5 1.4 0.097 12.9 1.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.15 ORX96633.1 - 1.1 9.2 4.2 4.8 7.2 4.2 1.9 1 1 0 1 1 1 0 Recombination endonuclease VII Iron_permease PF04120.12 ORX96654.1 - 2.4e-19 69.3 10.2 1.7e-07 31.0 0.2 3.2 3 0 0 3 3 3 3 Low affinity iron permease CUB PF00431.20 ORX96654.1 - 0.15 12.4 0.0 11 6.4 0.0 2.3 2 0 0 2 2 2 0 CUB domain BORG_CEP PF14957.6 ORX96656.1 - 5.3 8.2 10.1 4.1 8.6 0.2 3.1 3 0 0 3 3 3 0 Cdc42 effector Ldh_1_N PF00056.23 ORX96658.1 - 3.1e-48 163.5 0.1 4.8e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX96658.1 - 8.5e-46 155.9 0.1 1.8e-45 154.8 0.1 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 ORX96658.1 - 4.4e-05 22.6 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 ORX96658.1 - 0.0027 17.3 0.8 0.17 11.4 0.2 2.6 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase Pkinase PF00069.25 ORX96659.1 - 5.2e-69 232.6 0.0 6.9e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96659.1 - 1.3e-31 109.8 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX96659.1 - 9.6e-06 24.8 0.1 1.3e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX96659.1 - 0.00063 19.2 0.1 0.0024 17.2 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX96659.1 - 0.00098 19.1 0.0 0.0025 17.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX96659.1 - 0.0028 17.0 0.0 0.048 13.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 ORX96659.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX96659.1 - 0.042 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MyTH4 PF00784.17 ORX96660.1 - 5e-28 97.7 0.3 1.2e-27 96.6 0.3 1.7 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 ORX96660.1 - 4.6e-27 94.7 0.2 1.3e-26 93.3 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain WW PF00397.26 ORX96660.1 - 1e-06 28.7 6.2 0.0089 16.1 0.0 2.6 2 0 0 2 2 2 2 WW domain PWWP PF00855.17 ORX96661.1 - 2e-07 31.3 1.1 3e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 PWWP domain RBB1NT PF08169.11 ORX96661.1 - 0.088 13.0 0.0 0.48 10.6 0.0 2.4 1 1 0 1 1 1 0 RBB1NT (NUC162) domain Alginate_lyase PF05426.12 ORX96662.1 - 3.9e-74 249.6 0.0 4.5e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Forkhead PF00250.18 ORX96663.1 - 0.00078 19.7 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain DUF2718 PF10918.8 ORX96663.1 - 0.08 13.4 1.0 1.4 9.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) Wtap PF17098.5 ORX96665.1 - 5.9e-41 140.0 10.0 7.7e-41 139.6 10.0 1.1 1 0 0 1 1 1 1 WTAP/Mum2p family KLRAQ PF10205.9 ORX96665.1 - 0.0025 18.0 5.3 0.96 9.7 0.4 2.7 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein TMF_DNA_bd PF12329.8 ORX96665.1 - 0.0032 17.4 20.2 1.5 8.9 1.5 3.4 2 1 1 3 3 3 3 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 ORX96665.1 - 0.0037 17.8 7.1 0.007 17.0 0.4 3.3 3 1 0 3 3 3 1 SlyX DUF5082 PF16888.5 ORX96665.1 - 0.0053 17.0 6.0 0.18 12.1 4.8 3.3 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) ATG16 PF08614.11 ORX96665.1 - 0.0077 16.5 4.3 0.0077 16.5 4.3 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 ORX96665.1 - 0.012 16.1 2.2 0.16 12.4 0.1 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc29 PF17082.5 ORX96665.1 - 0.016 15.1 2.7 0.45 10.3 0.6 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 GHL13 PF14883.6 ORX96665.1 - 0.069 12.2 0.1 0.084 11.9 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Phasin PF05597.11 ORX96665.1 - 0.11 12.5 4.7 0.84 9.7 0.9 2.3 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 ORX96665.1 - 0.18 11.8 4.8 0.26 11.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 ORX96665.1 - 0.7 9.4 8.0 0.47 10.0 0.5 2.4 2 1 0 2 2 2 0 PspA/IM30 family TSC22 PF01166.18 ORX96665.1 - 0.82 10.0 9.8 0.83 10.0 0.2 3.6 4 1 1 5 5 4 0 TSC-22/dip/bun family UPF0242 PF06785.11 ORX96665.1 - 1 9.4 11.5 5.4 7.1 11.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 ORX96665.1 - 1 9.6 14.6 3.9 7.7 2.2 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 ORX96665.1 - 1.1 9.4 5.8 4.7 7.4 4.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 ORX96665.1 - 2 8.5 9.0 0.41 10.7 3.6 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 ORX96665.1 - 2 8.7 8.8 11 6.4 1.4 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 ORX96665.1 - 2.4 7.0 12.4 4.7 6.0 8.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GIT_CC PF16559.5 ORX96665.1 - 2.8 7.9 9.4 12 5.9 0.1 3.4 3 2 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Seryl_tRNA_N PF02403.22 ORX96665.1 - 3.8 7.8 13.3 0.63 10.3 1.0 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 ORX96665.1 - 3.9 7.6 13.0 0.17 12.1 0.9 2.7 1 1 0 2 2 2 0 Tropomyosin like DUF16 PF01519.16 ORX96665.1 - 6.1 7.4 10.4 1.3e+02 3.1 0.1 3.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Steroid_dh PF02544.16 ORX96666.1 - 7.5e-46 155.8 1.9 1.5e-45 154.9 1.9 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORX96666.1 - 6.3e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORX96666.1 - 0.0043 17.4 0.2 0.0043 17.4 0.2 2.8 2 2 2 4 4 4 1 Phospholipid methyltransferase KH_1 PF00013.29 ORX96668.1 - 1.9e-24 85.3 3.0 1.3e-07 31.3 0.0 6.0 6 0 0 6 6 6 5 KH domain zf-C2H2_6 PF13912.6 ORX96668.1 - 0.1 12.6 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Ras PF00071.22 ORX96669.1 - 4.7e-65 218.1 0.3 5.7e-65 217.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX96669.1 - 1.9e-35 121.7 0.1 2.8e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX96669.1 - 1.7e-16 60.2 0.1 2e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX96669.1 - 5.9e-06 25.8 0.1 7.1e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX96669.1 - 6.7e-06 25.8 1.2 1.2e-05 24.9 0.4 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX96669.1 - 4e-05 23.7 0.1 9.1e-05 22.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX96669.1 - 0.00019 21.4 0.2 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORX96669.1 - 0.00049 19.6 0.1 0.00061 19.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 ORX96669.1 - 0.0056 16.5 0.1 0.013 15.2 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ORX96669.1 - 0.012 15.4 0.0 0.21 11.3 0.0 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 ORX96669.1 - 0.027 14.0 0.1 0.22 11.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Synapsin_C PF02750.14 ORX96669.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Synapsin, ATP binding domain AAA_29 PF13555.6 ORX96669.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 ORX96669.1 - 0.094 11.8 0.2 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 ORX96669.1 - 0.12 12.8 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CTP_transf_like PF01467.26 ORX96670.1 - 2e-31 109.1 0.0 3.2e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 ORX96670.1 - 0.017 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5639) DUF5499 PF17603.2 ORX96670.1 - 0.11 13.1 1.0 0.29 11.8 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5499) Ras PF00071.22 ORX96671.1 - 1.6e-58 196.9 0.2 1.9e-58 196.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX96671.1 - 3.1e-32 111.3 0.0 4.7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX96671.1 - 3e-14 52.9 0.1 3.4e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX96671.1 - 3.1e-07 30.5 0.0 5.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX96671.1 - 6.2e-06 25.7 0.1 7.9e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX96671.1 - 2.4e-05 24.0 0.1 0.0011 18.5 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX96671.1 - 8.5e-05 22.5 0.2 0.0028 17.6 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase Septin PF00735.18 ORX96671.1 - 0.00077 18.8 0.3 0.0077 15.5 0.1 2.1 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 ORX96671.1 - 0.0008 19.3 0.4 0.022 14.5 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ORX96671.1 - 0.0015 18.3 0.1 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORX96671.1 - 0.0038 16.8 0.1 0.0093 15.6 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 ORX96671.1 - 0.0099 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORX96671.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX96671.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 ORX96671.1 - 0.015 15.6 0.0 0.046 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 ORX96671.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX96671.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 ORX96671.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ORX96671.1 - 0.072 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Latexin PF06907.12 ORX96671.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Latexin ATPase_2 PF01637.18 ORX96671.1 - 0.078 12.9 0.4 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 ORX96671.1 - 0.087 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 ORX96671.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 ORX96671.1 - 0.12 11.4 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain Pro_dh PF01619.18 ORX96672.1 - 4.2e-70 236.6 0.0 5.2e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 ORX96672.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel UDPGT PF00201.18 ORX96673.1 - 5.4e-27 94.8 0.1 5.9e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORX96673.1 - 2.2e-07 31.0 0.0 3.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ABC_membrane PF00664.23 ORX96692.1 - 7.7e-106 353.7 22.5 1.1e-59 202.4 4.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX96692.1 - 1.7e-69 232.6 0.1 7.5e-35 120.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX96692.1 - 2.1e-15 56.8 5.3 8.5e-06 25.4 0.4 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX96692.1 - 5.8e-08 32.8 0.0 0.0084 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORX96692.1 - 7.8e-08 32.0 0.1 0.0022 17.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORX96692.1 - 1.1e-07 31.1 0.4 0.0015 17.4 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORX96692.1 - 2.7e-07 30.9 0.3 0.011 16.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORX96692.1 - 2.9e-06 27.8 4.3 0.063 13.7 0.4 3.9 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORX96692.1 - 3e-06 26.6 0.0 0.048 12.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 ORX96692.1 - 4.1e-05 23.4 0.4 0.29 10.8 0.1 3.5 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 ORX96692.1 - 5.2e-05 22.6 0.0 0.085 12.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.6 ORX96692.1 - 0.00015 21.6 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 ORX96692.1 - 0.0002 21.3 0.7 0.29 10.9 0.0 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ORX96692.1 - 0.0002 21.8 0.3 4.4 7.7 0.0 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX96692.1 - 0.00021 21.3 0.1 0.84 9.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORX96692.1 - 0.00026 21.6 0.0 0.58 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORX96692.1 - 0.00056 20.5 0.0 0.075 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 ORX96692.1 - 0.00081 18.6 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 ORX96692.1 - 0.0012 19.0 0.5 1.5 9.0 0.5 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORX96692.1 - 0.0017 18.4 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PRK PF00485.18 ORX96692.1 - 0.0023 17.7 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 ORX96692.1 - 0.0029 17.8 2.6 4 7.8 0.3 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 ORX96692.1 - 0.005 15.9 0.2 0.7 8.8 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 ORX96692.1 - 0.0075 15.5 0.0 4.1 6.5 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_7 PF12775.7 ORX96692.1 - 0.011 15.2 0.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 ORX96692.1 - 0.012 15.7 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 ORX96692.1 - 0.012 15.3 0.0 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORX96692.1 - 0.016 15.1 0.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 ORX96692.1 - 0.02 14.8 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain KAP_NTPase PF07693.14 ORX96692.1 - 0.026 13.8 0.0 4.2 6.5 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain AAA_25 PF13481.6 ORX96692.1 - 0.036 13.6 0.0 8.6 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ORX96692.1 - 0.05 13.4 0.3 1.9 8.2 0.2 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 ORX96692.1 - 0.057 13.7 2.8 1.5 9.0 0.1 3.2 2 1 1 3 3 3 0 AAA domain MoeA_C PF03454.15 ORX96692.1 - 0.058 13.6 0.0 14 5.9 0.0 3.0 3 0 0 3 3 2 0 MoeA C-terminal region (domain IV) SRP54 PF00448.22 ORX96692.1 - 0.06 13.0 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 ORX96692.1 - 0.064 13.7 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 ORX96692.1 - 0.066 13.1 0.0 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 ORX96692.1 - 0.07 13.0 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 ORX96692.1 - 0.071 12.9 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 ORX96692.1 - 0.073 13.4 0.1 21 5.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 ORX96692.1 - 0.082 12.6 0.3 6.1 6.4 0.3 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 ORX96692.1 - 0.19 12.1 0.3 22 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 ORX96692.1 - 0.25 11.4 1.7 8.4 6.4 0.0 2.7 3 0 0 3 3 2 0 Dynamin family TRAM_LAG1_CLN8 PF03798.16 ORX96693.1 - 1.2e-22 80.6 17.2 1.2e-22 80.6 17.2 1.6 2 0 0 2 2 2 1 TLC domain DUF3980 PF13140.6 ORX96693.1 - 9.3 6.8 7.0 1.8 9.1 0.4 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3980) Glyco_transf_34 PF05637.12 ORX96694.1 - 8.3e-20 71.5 0.1 2e-18 67.0 0.1 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORX96694.1 - 6.6e-07 29.1 0.0 2.8e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 ORX96694.1 - 0.023 14.7 0.2 0.047 13.6 0.1 1.6 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase PetL PF05115.14 ORX96694.1 - 0.56 10.2 4.5 1.1 9.3 4.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) DUF4187 PF13821.6 ORX96695.1 - 5.7e-20 70.8 0.5 1.9e-19 69.1 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 ORX96695.1 - 1.8e-13 50.2 2.0 2.3e-13 49.8 0.2 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ORX96695.1 - 3.9e-05 23.7 0.1 0.00014 21.9 0.1 2.1 1 0 0 1 1 1 1 G-patch domain YonK PF09642.10 ORX96695.1 - 0.12 12.5 0.6 0.34 11.1 0.6 1.7 1 0 0 1 1 1 0 YonK protein STE PF02200.16 ORX96696.1 - 9.4e-56 187.0 0.1 1.1e-55 186.7 0.1 1.1 1 0 0 1 1 1 1 STE like transcription factor WD40 PF00400.32 ORX96697.1 - 4.7e-37 125.3 16.2 0.0017 19.2 0.0 11.6 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX96697.1 - 4.8e-18 65.2 0.0 0.00065 20.0 0.0 6.8 7 0 0 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORX96697.1 - 0.00052 19.9 0.2 0.92 9.5 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 ORX96697.1 - 0.012 15.6 0.1 5.1 7.2 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40_like PF17005.5 ORX96697.1 - 0.017 14.4 4.0 11 5.3 0.0 4.1 3 1 1 4 4 4 0 WD40-like domain Hira PF07569.11 ORX96697.1 - 0.023 14.4 0.2 2 8.0 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split Nbas_N PF15492.6 ORX96697.1 - 0.036 13.4 0.0 20 4.4 0.0 3.8 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 ORX96697.1 - 0.072 12.4 0.2 5.4 6.2 0.1 3.2 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Siah-Interact_N PF09032.11 ORX96697.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Siah interacting protein, N terminal Promethin PF16015.5 ORX96698.1 - 1.8e-10 40.7 0.3 2.6e-10 40.2 0.3 1.2 1 0 0 1 1 1 1 Promethin PspC PF04024.12 ORX96698.1 - 0.072 12.9 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 PspC domain Prominin PF05478.11 ORX96698.1 - 0.14 10.1 0.1 0.21 9.5 0.1 1.2 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.16 ORX96699.1 - 5e-11 42.1 45.9 1.3e-09 37.5 30.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORX96699.1 - 3.4e-09 36.6 10.5 3.4e-09 36.6 10.5 3.1 3 2 1 4 4 4 1 Ion channel regulatory protein UNC-93 SH PF01445.17 ORX96699.1 - 1.2 9.2 5.1 3.1 7.8 0.3 2.9 2 0 0 2 2 2 0 Viral small hydrophobic protein ThiF PF00899.21 ORX96700.1 - 1.1e-58 198.5 0.2 1.6e-58 197.9 0.2 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 ORX96700.1 - 2e-14 54.0 0.0 6.5e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 ORX96700.1 - 0.0018 18.4 0.3 0.051 13.6 0.1 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORX96700.1 - 0.005 17.3 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DapB_N PF01113.20 ORX96700.1 - 0.012 15.7 0.1 0.032 14.4 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.21 ORX96700.1 - 0.13 12.0 0.1 0.29 10.8 0.0 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ZapB PF06005.12 ORX96700.1 - 0.23 11.9 5.9 0.52 10.8 5.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Sacchrp_dh_NADP PF03435.18 ORX96700.1 - 2.2 8.6 6.0 25 5.1 6.0 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Bap31_Bap29_C PF18035.1 ORX96700.1 - 4.6 7.3 5.5 1.9 8.5 2.9 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RNA_pol_Rpb1_2 PF00623.20 ORX96701.1 - 3.1e-13 50.3 0.1 1.2e-10 41.9 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 2 zf-MYND PF01753.18 ORX96701.1 - 0.12 12.5 5.5 0.28 11.3 5.5 1.6 1 0 0 1 1 1 0 MYND finger zf-ribbon_3 PF13248.6 ORX96701.1 - 0.12 11.8 3.7 0.34 10.4 3.7 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 ORX96701.1 - 0.14 12.0 1.6 0.31 10.8 1.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain 2OG-FeII_Oxy_2 PF13532.6 ORX96703.1 - 1.8e-14 54.4 0.0 4.3e-14 53.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 ORX96703.1 - 0.058 13.9 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CBS PF00571.28 ORX96704.1 - 1.6e-34 118.1 1.4 3.8e-08 33.6 0.0 4.3 4 0 0 4 4 4 4 CBS domain SRF-TF PF00319.18 ORX96706.1 - 1.1e-17 63.2 0.3 1.5e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PRA-CH PF01502.18 ORX96706.1 - 0.011 15.6 0.4 0.014 15.2 0.4 1.3 1 1 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase Pkinase PF00069.25 ORX96707.1 - 1.1e-52 179.1 0.0 3.6e-52 177.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96707.1 - 1.6e-23 83.3 0.0 2.2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX96707.1 - 0.00074 19.5 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX96707.1 - 0.0024 17.2 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX96707.1 - 0.0098 14.9 0.1 0.026 13.5 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX96707.1 - 0.031 13.6 0.2 0.045 13.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX96707.1 - 0.04 13.5 0.3 2.1 7.9 0.0 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORX96709.1 - 1.6e-39 135.9 0.0 1.8e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96709.1 - 3.8e-18 65.7 0.0 4.5e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX96709.1 - 6.4e-07 29.0 0.0 1.4e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORX96709.1 - 0.00044 20.3 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORX96709.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 ORX96709.1 - 0.022 13.7 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORX96709.1 - 0.059 12.7 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family peroxidase PF00141.23 ORX96718.1 - 2.1e-40 138.8 0.0 3e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Phos_pyr_kin PF08543.12 ORX96720.1 - 4.1e-85 285.1 3.0 4.1e-85 285.1 3.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 ORX96720.1 - 9.3e-38 130.1 0.2 1.8e-37 129.2 0.2 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 ORX96720.1 - 6.7e-06 25.6 0.2 3.7e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 ORX96720.1 - 0.017 14.6 1.1 0.12 11.9 0.5 2.2 2 0 0 2 2 2 0 Carbohydrate kinase DUF1846 PF08903.11 ORX96720.1 - 0.14 10.7 1.0 5.2 5.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) UDG PF03167.19 ORX96720.1 - 0.23 11.5 1.1 1.5 8.8 0.0 2.6 2 2 1 3 3 3 0 Uracil DNA glycosylase superfamily CH PF00307.31 ORX96721.1 - 1.1e-83 276.6 2.3 2.6e-20 72.6 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORX96721.1 - 1.9e-11 43.6 0.2 0.001 18.9 0.0 3.8 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_1 PF00036.32 ORX96721.1 - 6.8e-09 34.7 6.3 0.00072 18.9 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 ORX96721.1 - 4.9e-07 29.5 1.4 2.3e-06 27.4 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 ORX96721.1 - 4.9e-07 30.1 3.7 5.3e-07 30.0 2.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORX96721.1 - 8e-06 25.4 4.9 0.00062 19.5 0.6 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 ORX96721.1 - 5.8e-05 22.4 1.8 0.00012 21.4 0.2 2.4 2 0 0 2 2 2 1 EF hand CH_2 PF06294.11 ORX96721.1 - 0.0027 17.8 0.2 1.1 9.4 0.0 3.2 3 0 0 3 3 3 1 CH-like domain in sperm protein TerB PF05099.13 ORX96721.1 - 0.021 14.8 0.7 0.14 12.1 0.1 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 ORX96721.1 - 0.04 14.2 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 ORX96721.1 - 0.13 12.0 1.3 0.2 11.4 0.4 1.7 2 0 0 2 2 2 0 SurA N-terminal domain Pro_dh PF01619.18 ORX96722.1 - 7.9e-69 232.4 0.0 1.1e-68 231.9 0.0 1.4 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 ORX96722.1 - 8.3e-06 26.2 0.1 1.9e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORX96722.1 - 0.00029 20.2 0.2 0.013 15.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORX96722.1 - 0.02 14.7 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair PEP-utilisers_N PF05524.13 ORX96722.1 - 0.022 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal EF-hand_6 PF13405.6 ORX96722.1 - 0.029 14.3 0.2 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 ORX96722.1 - 0.078 12.5 1.8 0.15 11.6 0.3 2.1 2 0 0 2 2 2 0 EF hand Ras PF00071.22 ORX96724.1 - 9.5e-59 197.6 0.2 1.1e-58 197.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX96724.1 - 3e-32 111.3 0.0 4.7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX96724.1 - 2.7e-14 53.0 0.1 3.1e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX96724.1 - 2.9e-07 30.6 0.0 5.6e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX96724.1 - 5.3e-06 25.9 0.1 6.8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX96724.1 - 2.5e-05 23.9 0.1 0.0012 18.5 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX96724.1 - 8.2e-05 22.6 0.2 0.0028 17.6 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 ORX96724.1 - 0.00065 19.5 0.4 0.019 14.8 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 ORX96724.1 - 0.00098 18.5 0.3 0.0099 15.2 0.1 2.2 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 ORX96724.1 - 0.0013 18.5 0.1 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORX96724.1 - 0.004 16.8 0.1 0.0093 15.6 0.0 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 ORX96724.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORX96724.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORX96724.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 ORX96724.1 - 0.014 15.7 0.0 0.045 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 ORX96724.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORX96724.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 ORX96724.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ORX96724.1 - 0.07 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 ORX96724.1 - 0.075 12.9 0.4 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 ORX96724.1 - 0.084 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 ORX96724.1 - 0.092 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 ORX96724.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 ORX96724.1 - 0.14 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain G-alpha PF00503.20 ORX96724.1 - 0.24 10.5 1.5 0.6 9.2 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit LZ3wCH PF18517.1 ORX96725.1 - 0.029 14.5 0.0 0.029 14.5 0.0 1.9 2 0 0 2 2 2 0 Leucine zipper with capping helix domain KH_1 PF00013.29 ORX96726.1 - 4.8e-24 84.0 1.3 6.2e-08 32.4 0.0 5.6 5 0 0 5 5 5 5 KH domain Steroid_dh PF02544.16 ORX96727.1 - 5.8e-48 162.7 0.8 9e-48 162.1 0.8 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORX96727.1 - 5.4e-05 23.5 0.1 5.4e-05 23.5 0.1 3.2 3 1 2 5 5 5 1 Phospholipid methyltransferase DUF1295 PF06966.12 ORX96727.1 - 0.00026 20.6 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1353 PF07087.11 ORX96727.1 - 0.044 13.5 0.0 5.4 6.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1353) RhoGAP PF00620.27 ORX96728.1 - 9.2e-44 148.9 0.0 1.9e-43 147.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORX96728.1 - 1.5e-18 66.8 26.4 6.6e-11 42.3 4.6 3.1 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 ORX96728.1 - 3.8e-08 33.1 9.7 3.8e-08 33.1 9.7 4.4 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_Tnp_ISL3 PF01610.17 ORX96728.1 - 0.011 15.4 4.7 0.14 11.8 5.7 2.1 2 0 0 2 2 2 0 Transposase CorA PF01544.18 ORX96728.1 - 3.4 6.9 7.0 6 6.1 7.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4709 PF15821.5 ORX96728.1 - 8.8 6.7 10.7 96 3.3 10.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) Wtap PF17098.5 ORX96729.1 - 2.8e-28 98.8 7.4 3.7e-27 95.2 7.4 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family Osmo_CC PF08946.10 ORX96729.1 - 0.15 12.3 1.7 8.7 6.7 0.0 3.3 3 1 0 3 3 3 0 Osmosensory transporter coiled coil DUF5082 PF16888.5 ORX96729.1 - 0.32 11.3 4.1 7.4 6.9 0.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF641 PF04859.12 ORX96729.1 - 1.3 9.3 6.3 2.5 8.5 0.4 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 ORX96729.1 - 2.4 8.5 8.2 4 7.9 0.1 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Med9 PF07544.13 ORX96729.1 - 2.5 8.3 8.7 19 5.4 4.5 3.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Ribonuclease_P PF00825.18 ORX96730.1 - 2.8e-06 27.4 1.1 3e-06 27.3 1.1 1.0 1 0 0 1 1 1 1 Ribonuclease P DUF5082 PF16888.5 ORX96731.1 - 0.11 12.8 3.3 0.2 11.9 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Forkhead PF00250.18 ORX96732.1 - 3e-07 30.6 0.0 5.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain PIN_10 PF18478.1 ORX96732.1 - 0.22 11.7 0.9 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 PIN like domain Sec61_beta PF03911.16 ORX96733.1 - 1.7e-15 56.8 0.4 2e-15 56.5 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family Alginate_lyase PF05426.12 ORX96734.1 - 3.4e-76 256.4 0.0 3.8e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Ras PF00071.22 ORX96735.1 - 1.8e-60 203.3 0.2 2.2e-60 202.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX96735.1 - 5.2e-37 126.7 0.1 7.4e-37 126.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX96735.1 - 1.8e-15 56.8 0.3 2.2e-15 56.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORX96735.1 - 2.1e-06 27.3 0.1 4.9e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORX96735.1 - 2.2e-06 27.3 0.1 1.4e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX96735.1 - 3.6e-05 23.8 0.1 6.7e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORX96735.1 - 0.00011 21.7 0.2 0.00013 21.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 ORX96735.1 - 0.00025 20.6 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX96735.1 - 0.00043 20.2 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 ORX96735.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIR_2 PF13676.6 ORX96735.1 - 0.15 12.7 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 TIR domain PWWP PF00855.17 ORX96736.1 - 2.1e-06 28.1 0.1 5.8e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 PWWP domain TerY_C PF15616.6 ORX96736.1 - 0.061 13.4 2.4 0.1 12.7 2.4 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain RBB1NT PF08169.11 ORX96736.1 - 0.083 13.0 0.0 0.31 11.2 0.0 2.1 1 1 0 1 1 1 0 RBB1NT (NUC162) domain Coilin_N PF15862.5 ORX96737.1 - 6e-12 45.5 0.1 6e-12 45.5 0.1 3.0 3 1 0 3 3 3 1 Coilin N-terminus ORMDL PF04061.14 ORX96738.1 - 2e-52 176.6 3.3 2.3e-52 176.4 3.3 1.1 1 0 0 1 1 1 1 ORMDL family CN_hydrolase PF00795.22 ORX96739.1 - 5.5e-43 147.2 0.0 7.7e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 ORX96739.1 - 5.3e-22 78.1 0.0 1.6e-21 76.5 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 ORX96739.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase MyTH4 PF00784.17 ORX96740.1 - 8.1e-26 90.6 0.1 1.6e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 ORX96740.1 - 5.2e-12 45.8 0.3 1.1e-09 38.3 0.1 2.9 2 1 1 3 3 3 2 RhoGAP domain WW PF00397.26 ORX96740.1 - 3.9e-07 30.0 6.1 0.005 16.9 0.1 2.5 2 0 0 2 2 2 2 WW domain SAM_1 PF00536.30 ORX96740.1 - 0.0051 17.2 0.1 2.1 8.9 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase PF00069.25 ORX96741.1 - 2.9e-69 233.4 0.0 4e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96741.1 - 3.6e-31 108.4 0.0 5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX96741.1 - 9.1e-06 24.8 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX96741.1 - 0.00057 19.3 0.1 0.0021 17.4 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX96741.1 - 0.00097 19.1 0.0 0.0025 17.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX96741.1 - 0.0074 15.6 0.0 0.035 13.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 ORX96741.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX96741.1 - 0.036 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ldh_1_N PF00056.23 ORX96742.1 - 6.6e-48 162.4 0.2 1e-47 161.8 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX96742.1 - 7.8e-40 136.5 0.0 1.5e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 ORX96742.1 - 2.9e-05 23.2 0.0 4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 ORX96742.1 - 0.0079 15.8 0.4 3.7 7.1 0.1 3.1 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.6 ORX96742.1 - 0.018 15.0 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding MMU163 PF17119.5 ORX96743.1 - 0.025 13.7 4.8 0.032 13.4 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Presenilin PF01080.17 ORX96743.1 - 0.059 12.1 10.5 0.068 11.9 10.5 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 ORX96743.1 - 0.21 10.8 8.1 0.26 10.5 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mucin PF01456.17 ORX96743.1 - 0.56 10.2 8.7 0.68 9.9 8.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Nop14 PF04147.12 ORX96743.1 - 0.62 8.2 19.8 0.69 8.1 19.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF5427 PF10310.9 ORX96743.1 - 2.1 7.2 17.1 2.3 7.1 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 ORX96743.1 - 3.3 6.6 11.3 3.8 6.4 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 ORX96743.1 - 4.4 4.3 12.1 4.9 4.1 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 ORX96743.1 - 4.4 7.3 7.6 6.5 6.7 7.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 ORX96743.1 - 5.7 6.7 13.9 6.8 6.4 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pneumo_att_G PF05539.11 ORX96743.1 - 8.8 5.8 21.2 11 5.5 21.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hid1 PF12722.7 ORX96743.1 - 9.6 4.2 16.4 11 4.0 16.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Folate_carrier PF01770.18 ORX96744.1 - 0.34 9.6 3.1 1.8 7.2 0.3 2.3 2 1 0 2 2 2 0 Reduced folate carrier ABC_tran PF00005.27 ORX96745.1 - 1.9e-41 141.8 2.0 7.7e-26 91.2 0.0 4.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORX96745.1 - 1.8e-09 37.9 0.0 0.017 15.0 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX96745.1 - 3.6e-08 33.1 0.1 0.00055 19.4 0.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORX96745.1 - 1.7e-07 31.9 3.0 0.02 15.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORX96745.1 - 2.3e-07 30.9 0.2 0.011 15.7 0.1 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORX96745.1 - 3.1e-07 30.0 0.0 0.03 14.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 ORX96745.1 - 4.7e-07 29.6 0.3 1.1e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 4HB PF17947.1 ORX96745.1 - 8.4e-07 29.0 0.0 2.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Four helical bundle domain MMR_HSR1 PF01926.23 ORX96745.1 - 1.4e-05 25.2 0.0 0.12 12.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ORX96745.1 - 2.1e-05 25.1 0.0 0.086 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORX96745.1 - 2.7e-05 24.5 0.0 0.35 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 ORX96745.1 - 3.8e-05 22.8 0.5 0.048 12.6 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 ORX96745.1 - 5.4e-05 23.5 0.1 0.68 10.3 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_16 PF13191.6 ORX96745.1 - 0.00012 22.5 0.1 1.1 9.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 ORX96745.1 - 0.00013 22.4 0.0 0.22 12.0 0.0 3.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORX96745.1 - 0.00018 21.5 0.0 0.057 13.3 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 ORX96745.1 - 0.00024 20.9 0.5 2.3 7.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ORX96745.1 - 0.00027 21.2 0.0 0.2 11.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 ORX96745.1 - 0.00033 20.8 0.0 0.59 10.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 ORX96745.1 - 0.00055 20.1 0.1 0.036 14.1 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_27 PF13514.6 ORX96745.1 - 0.0011 18.6 0.1 0.86 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORX96745.1 - 0.0012 18.8 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 ORX96745.1 - 0.0025 17.6 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain CLASP_N PF12348.8 ORX96745.1 - 0.0026 17.4 0.0 0.0067 16.0 0.0 1.7 1 0 0 1 1 1 1 CLASP N terminal AAA_24 PF13479.6 ORX96745.1 - 0.0026 17.5 0.0 2.1 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORX96745.1 - 0.02 14.8 0.0 2.2 8.1 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORX96745.1 - 0.026 14.0 0.0 8.6 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 ORX96745.1 - 0.028 14.6 0.0 0.16 12.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Vac14_Fab1_bd PF12755.7 ORX96745.1 - 0.028 15.0 0.0 9.9 6.8 0.0 2.8 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Roc PF08477.13 ORX96745.1 - 0.032 14.4 0.0 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORX96745.1 - 0.034 13.9 0.1 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 ORX96745.1 - 0.042 13.9 0.0 4.5 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 ORX96745.1 - 0.054 13.8 0.0 5.1 7.6 0.0 3.7 3 0 0 3 3 2 0 HEAT repeat NTPase_1 PF03266.15 ORX96745.1 - 0.061 13.2 0.1 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 ORX96745.1 - 0.068 12.9 0.2 4.6 6.9 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein DUF815 PF05673.13 ORX96745.1 - 0.073 12.2 0.0 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MukB PF04310.12 ORX96745.1 - 0.084 12.7 0.0 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 MukB N-terminal Cytidylate_kin PF02224.18 ORX96745.1 - 0.088 12.5 0.1 17 5.0 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Dynamin_N PF00350.23 ORX96745.1 - 0.21 11.6 1.5 1.1 9.3 0.0 2.7 3 0 0 3 3 2 0 Dynamin family HEAT_EZ PF13513.6 ORX96745.1 - 7.8 7.1 8.2 12 6.5 0.0 4.6 6 0 0 6 6 4 0 HEAT-like repeat peroxidase PF00141.23 ORX96746.1 - 7.6e-40 137.0 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Cyclin_N PF00134.23 ORX96770.1 - 2.1e-14 53.4 0.1 2.5e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX96770.1 - 3.8e-12 46.9 0.6 4.6e-12 46.6 0.6 1.0 1 0 0 1 1 1 1 Cyclin DUF2244 PF10003.9 ORX96771.1 - 0.068 12.8 1.0 0.11 12.1 1.0 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) UPF0014 PF03649.13 ORX96771.1 - 0.19 11.0 2.8 0.28 10.5 2.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) TMEM171 PF15471.6 ORX96771.1 - 0.25 10.3 0.6 0.37 9.7 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-H2C2_2 PF13465.6 ORX96772.1 - 1.5e-24 85.2 23.4 8.5e-10 38.6 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX96772.1 - 1.6e-21 75.5 30.4 2.7e-06 27.5 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX96772.1 - 1e-13 50.8 26.5 0.0016 19.1 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96772.1 - 1.1e-05 25.6 10.9 0.27 11.6 0.8 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX96772.1 - 1.7e-05 25.0 10.7 0.00084 19.6 1.7 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORX96772.1 - 0.00062 20.1 11.7 6.3 7.3 0.5 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORX96772.1 - 0.0078 16.8 6.6 0.73 10.5 0.7 3.3 3 0 0 3 3 3 1 FOXP coiled-coil domain DUF448 PF04296.13 ORX96772.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF448) Ribosomal_L5_C PF00673.21 ORX96772.1 - 0.057 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 ribosomal L5P family C-terminus zf-TRAF PF02176.18 ORX96772.1 - 0.17 12.6 11.7 0.13 13.0 3.5 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 ORX96772.1 - 0.46 10.3 22.7 0.066 13.0 4.5 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 ORX96772.1 - 0.57 10.3 8.0 6.8 6.8 0.0 3.3 4 0 0 4 4 4 0 Aberrant zinc-finger zf-DNA_Pol PF08996.10 ORX96772.1 - 1 9.1 7.1 0.72 9.6 2.9 2.1 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 ORX96772.1 - 1.4 9.0 17.2 0.52 10.4 0.7 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-tcix PF14952.6 ORX96772.1 - 2.4 7.9 6.3 8.6 6.1 0.2 3.6 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding Zn-ribbon_8 PF09723.10 ORX96772.1 - 2.8 8.1 9.1 0.99 9.6 1.2 3.2 3 2 1 4 4 4 0 Zinc ribbon domain Ogr_Delta PF04606.12 ORX96772.1 - 7.6 6.6 11.3 8.7 6.4 2.1 2.9 2 2 1 3 3 3 0 Ogr/Delta-like zinc finger RGS PF00615.19 ORX96773.1 - 2.8e-17 63.1 0.1 4.4e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX96773.1 - 1.5e-06 28.1 24.5 5.7e-06 26.2 24.5 1.9 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RGS-like PF09128.11 ORX96773.1 - 0.02 14.6 0.1 0.079 12.7 0.1 2.0 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DUF5058 PF16481.5 ORX96773.1 - 1.9 8.1 13.5 2.3 7.9 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5058) CLIP1_ZNF PF16641.5 ORX96774.1 - 7e-12 44.9 15.4 3.4e-08 33.2 8.0 2.3 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 ORX96774.1 - 0.0066 15.4 14.4 0.0082 15.1 14.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein GPS2_interact PF15784.5 ORX96774.1 - 0.0079 16.6 2.6 0.0079 16.6 2.6 2.8 1 1 1 2 2 2 1 G-protein pathway suppressor 2-interacting domain MbeD_MobD PF04899.12 ORX96774.1 - 0.011 15.9 0.9 0.063 13.4 0.9 2.2 1 1 0 1 1 1 0 MbeD/MobD like ANT PF03374.14 ORX96774.1 - 0.017 15.4 0.5 6.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain SidE PF12252.8 ORX96774.1 - 0.038 11.5 6.2 0.043 11.4 6.2 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein YlqD PF11068.8 ORX96774.1 - 0.056 13.8 15.1 0.06 13.7 14.4 1.4 1 1 0 1 1 1 0 YlqD protein eIF3g PF12353.8 ORX96774.1 - 0.1 13.0 0.2 0.1 13.0 0.2 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G TolA_bind_tri PF16331.5 ORX96774.1 - 0.11 12.6 11.8 0.48 10.5 4.5 2.5 3 0 0 3 3 2 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 ORX96774.1 - 0.12 12.4 14.1 0.19 11.8 3.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2252 PF10009.9 ORX96774.1 - 0.25 10.4 3.1 0.32 10.0 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Exonuc_VII_L PF02601.15 ORX96774.1 - 0.4 10.2 6.1 0.48 10.0 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ESM4 PF15952.5 ORX96774.1 - 0.43 11.0 6.2 0.57 10.6 6.2 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family CLZ PF16526.5 ORX96774.1 - 0.6 10.5 14.7 1.2 9.5 4.1 2.7 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dam1 PF08653.10 ORX96774.1 - 0.63 9.9 4.4 11 5.9 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 B277 PF17623.2 ORX96774.1 - 0.74 8.8 4.2 1 8.4 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DHR10 PF18595.1 ORX96774.1 - 1.1 9.3 23.3 2.4 8.2 16.0 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain HIP1_clath_bdg PF16515.5 ORX96774.1 - 1.1 9.9 15.3 0.68 10.6 12.3 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 ORX96774.1 - 1.6 8.8 17.4 1.3 9.1 5.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc29 PF17082.5 ORX96774.1 - 1.8 8.3 13.5 6.2 6.6 13.4 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 FAM76 PF16046.5 ORX96774.1 - 3.1 7.1 16.3 19 4.5 15.6 2.1 1 1 1 2 2 2 0 FAM76 protein DUF724 PF05266.14 ORX96774.1 - 3.4 7.5 16.8 1.5 8.6 14.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 ORX96774.1 - 3.6 6.8 13.0 4.6 6.5 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlgN PF05130.12 ORX96774.1 - 4.5 7.8 16.2 4.2 7.9 1.6 2.4 1 1 1 2 2 2 0 FlgN protein Fzo_mitofusin PF04799.13 ORX96774.1 - 8.8 5.8 11.2 31 4.1 8.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region Acetyltransf_9 PF13527.7 ORX96775.1 - 1.1e-07 32.0 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX96775.1 - 0.0002 21.8 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX96775.1 - 0.00074 19.7 0.0 0.0052 17.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ORX96775.1 - 0.044 13.9 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ORX96775.1 - 0.056 13.4 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_S6e PF01092.19 ORX96776.1 - 1.7e-60 202.5 0.0 3.6e-60 201.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e UCR_14kD PF02271.16 ORX96777.1 - 1e-41 140.9 0.4 1.2e-41 140.7 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit CNH PF00780.22 ORX96778.1 - 2.1e-76 257.2 0.0 7.7e-76 255.3 0.0 1.8 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 ORX96778.1 - 1e-36 126.9 0.0 1.8e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORX96778.1 - 8.9e-30 103.5 0.0 1.9e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORX96778.1 - 2e-15 56.6 0.2 4.5e-15 55.5 0.2 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 ORX96778.1 - 0.0016 19.0 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 ORX96778.1 - 0.04 13.8 0.4 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 PH domain Lebercilin PF15619.6 ORX96780.1 - 0.0038 16.9 25.8 0.0038 16.9 25.8 3.9 2 2 1 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease PRKG1_interact PF15898.5 ORX96780.1 - 0.0041 18.0 10.7 0.0041 18.0 10.7 5.3 4 1 1 5 5 5 1 cGMP-dependent protein kinase interacting domain EF-hand_7 PF13499.6 ORX96780.1 - 0.031 14.7 0.4 0.13 12.7 0.4 2.2 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 ORX96780.1 - 0.045 13.7 0.6 0.29 11.2 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain Dzip-like_N PF13815.6 ORX96780.1 - 0.081 12.9 0.3 0.081 12.9 0.3 3.7 5 0 0 5 5 5 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FlaC_arch PF05377.11 ORX96780.1 - 1.5 9.3 16.8 0.9 10.0 0.6 5.1 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) YabA PF06156.13 ORX96780.1 - 1.7 9.3 33.4 0.38 11.4 1.3 5.6 4 2 2 6 6 6 0 Initiation control protein YabA DUF812 PF05667.11 ORX96780.1 - 4.7 6.0 34.8 0.39 9.6 0.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF812) Filament PF00038.21 ORX96780.1 - 5 6.6 38.6 0.3 10.6 4.8 4.1 2 1 0 3 3 3 0 Intermediate filament protein F-box-like PF12937.7 ORX96781.1 - 4.1e-08 33.0 0.3 4.1e-08 33.0 0.3 3.5 5 0 0 5 5 5 1 F-box-like LRR_8 PF13855.6 ORX96781.1 - 0.0011 18.7 7.0 0.95 9.3 0.1 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORX96781.1 - 0.074 13.5 14.8 0.4 11.2 0.1 6.7 8 1 2 10 10 10 0 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.26 ORX96782.1 - 4.9e-24 83.4 25.7 5.7e-08 32.8 0.1 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX96782.1 - 4e-23 80.8 23.6 2.3e-08 34.1 0.2 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX96782.1 - 3.2e-15 55.5 21.1 6.5e-05 23.4 0.1 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96782.1 - 5.2e-10 39.3 13.0 0.00013 22.1 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX96782.1 - 2.3e-06 27.8 12.2 0.014 15.7 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX96782.1 - 0.00046 20.1 14.9 0.095 12.7 0.1 4.6 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORX96782.1 - 0.0011 18.8 10.7 0.11 12.4 1.6 3.5 3 1 0 3 3 3 2 zinc-finger of a C2HC-type HTH_18 PF12833.7 ORX96782.1 - 0.0021 18.3 1.2 4 7.8 0.3 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain FOXP-CC PF16159.5 ORX96782.1 - 0.0043 17.7 4.2 0.016 15.8 0.8 2.8 2 2 0 2 2 2 1 FOXP coiled-coil domain zf-TRAF PF02176.18 ORX96782.1 - 0.028 15.1 2.6 0.028 15.1 2.6 2.1 1 1 2 3 3 3 0 TRAF-type zinc finger GAGA PF09237.11 ORX96782.1 - 0.032 14.0 0.5 0.032 14.0 0.5 1.9 1 1 0 2 2 2 0 GAGA factor Zn-C2H2_12 PF18112.1 ORX96782.1 - 0.037 14.5 1.0 23 5.6 0.1 3.5 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF2180 PF09947.9 ORX96782.1 - 0.061 13.3 1.5 0.1 12.6 1.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Zn-ribbon_8 PF09723.10 ORX96782.1 - 1.6 8.9 6.1 1 9.5 1.1 2.8 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 ORX96782.1 - 5.4 6.9 16.7 0.14 11.9 1.2 3.6 4 0 0 4 4 4 0 zinc-finger C2H2-type DUF4448 PF14610.6 ORX96783.1 - 3.5e-06 26.9 0.4 1.7e-05 24.7 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 ORX96783.1 - 0.041 14.8 0.0 0.074 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 ORX96783.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Cortical protein marker for cell polarity VSP PF03302.13 ORX96783.1 - 0.18 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Trypsin PF00089.26 ORX96784.1 - 1.8e-39 135.9 0.0 2.1e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORX96784.1 - 1.9e-06 28.8 0.0 2.8e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 ORX96784.1 - 0.011 16.1 0.2 0.024 15.0 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1986) Cyclin_N PF00134.23 ORX96785.1 - 3.2e-10 39.9 0.0 3.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORX96785.1 - 4e-10 40.3 0.0 4.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin AMP-binding PF00501.28 ORX96787.1 - 2.7e-99 332.6 0.0 3.3e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX96787.1 - 1.1e-15 58.4 0.3 5.1e-15 56.2 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GARS_A PF01071.19 ORX96787.1 - 0.05 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AAA PF00004.29 ORX96788.1 - 4.8e-14 52.9 0.0 1.3e-13 51.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORX96788.1 - 9.5e-05 22.4 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX96788.1 - 0.00037 20.9 0.0 0.0016 18.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX96788.1 - 0.00058 20.1 0.0 0.0027 18.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORX96788.1 - 0.018 14.4 0.2 0.058 12.8 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORX96788.1 - 0.025 14.5 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 ORX96788.1 - 0.046 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX96788.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORX96788.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_2 PF07724.14 ORX96788.1 - 0.098 12.8 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORX96788.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ORX96788.1 - 0.15 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 ORX96788.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CBAH PF02275.18 ORX96789.1 - 0.01 15.5 0.2 0.014 15.1 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family FlaG PF03646.15 ORX96790.1 - 0.37 11.0 5.7 0.082 13.1 1.8 2.0 2 0 0 2 2 2 0 FlaG protein Sigma70_ner PF04546.13 ORX96790.1 - 0.41 10.5 8.4 0.68 9.8 8.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SNF2_N PF00176.23 ORX96791.1 - 1.5e-23 83.1 0.2 2.5e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORX96791.1 - 0.0067 16.4 0.2 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Kelch_5 PF13854.6 ORX96791.1 - 0.019 15.0 2.0 3.4 7.8 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 ORX96791.1 - 5.8 7.3 4.9 34 4.9 0.1 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain Helicase_C PF00271.31 ORX96792.1 - 3.1e-06 27.5 0.0 3.6e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.24 ORX96814.1 - 1.3e-94 317.7 18.2 1.5e-94 317.4 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX96814.1 - 5.6e-24 84.7 62.6 6.9e-22 77.8 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EcpB_C PF18649.1 ORX96815.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 EcpB C-terminal domain Mid2 PF04478.12 ORX96818.1 - 0.15 11.9 0.8 0.23 11.3 0.8 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4366 PF14283.6 ORX96818.1 - 1.8 8.6 7.9 40 4.2 7.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Podoplanin PF05808.11 ORX96818.1 - 7.9 6.6 10.4 9.6 6.3 8.8 1.8 1 1 1 2 2 2 0 Podoplanin RasGEF PF00617.19 ORX96819.1 - 7.3e-19 68.6 0.3 1.9e-09 38.0 0.0 2.5 1 1 1 2 2 2 2 RasGEF domain PfkB PF00294.24 ORX96820.1 - 1.8e-17 63.6 0.3 5.4e-17 62.1 0.3 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DctP PF03480.13 ORX96820.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Tape_meas_lam_C PF09718.10 ORX96821.1 - 0.06 13.5 1.0 0.13 12.4 1.0 1.7 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Big_2 PF02368.18 ORX96821.1 - 0.17 11.8 4.4 0.23 11.4 4.4 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) NDK PF00334.19 ORX96823.1 - 1.3e-38 132.1 0.0 1.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SH3_1 PF00018.28 ORX96824.1 - 2.1e-08 33.7 0.2 2.1e-08 33.7 0.2 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORX96824.1 - 6e-07 29.2 0.0 2.2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORX96824.1 - 3.4e-05 23.4 0.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain CitMHS_2 PF16980.5 ORX96824.1 - 0.0064 15.2 2.1 0.0084 14.8 2.1 1.1 1 0 0 1 1 1 1 Putative citrate transport SAP PF02037.27 ORX96824.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain SLAC1 PF03595.17 ORX96824.1 - 0.021 14.1 11.5 0.035 13.4 11.5 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF4407 PF14362.6 ORX96824.1 - 0.075 12.4 5.8 0.16 11.3 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4173 PF13777.6 ORX96824.1 - 0.14 11.6 4.9 0.21 11.0 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Fer2 PF00111.27 ORX96825.1 - 1.1e-12 47.7 0.2 1.5e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 ORX96825.1 - 0.064 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Magnetochrome domain Erf4 PF10256.9 ORX96826.1 - 5.6e-30 103.8 0.1 6.5e-30 103.6 0.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family FliG_N PF14842.6 ORX96827.1 - 0.16 12.5 0.1 0.7 10.5 0.0 2.1 2 0 0 2 2 2 0 FliG N-terminal domain C2 PF00168.30 ORX96828.1 - 4.2e-17 62.3 0.0 9.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 ORX96828.1 - 4.2e-13 49.7 5.8 3.8e-06 27.1 0.1 3.1 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 ORX96828.1 - 6.2e-06 25.1 0.6 8.9e-06 24.5 0.6 1.2 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) FA_FANCE PF11510.8 ORX96829.1 - 4.8e-16 58.9 5.6 2.6e-15 56.5 5.6 1.9 1 1 0 1 1 1 1 Fanconi Anaemia group E protein FANCE U3snoRNP10 PF12397.8 ORX96829.1 - 0.055 13.8 1.8 0.59 10.5 0.2 2.8 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 5-FTHF_cyc-lig PF01812.20 ORX96830.1 - 3.5e-45 154.2 0.0 4.7e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family FH2 PF02181.23 ORX96831.1 - 2.2e-83 280.5 20.3 2.2e-83 280.5 20.3 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORX96831.1 - 1.1e-43 149.0 1.4 1.1e-43 149.0 1.4 2.7 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORX96831.1 - 7.3e-16 58.4 0.1 7.3e-16 58.4 0.1 2.8 3 1 0 3 3 3 1 Diaphanous FH3 Domain Drf_DAD PF06345.11 ORX96831.1 - 0.017 15.1 0.2 0.053 13.6 0.2 1.9 1 0 0 1 1 1 0 DRF Autoregulatory Domain YcaO_C PF18381.1 ORX96831.1 - 0.018 14.9 1.0 4.6 7.1 0.0 3.3 3 0 0 3 3 3 0 YcaO cyclodehydratase C-terminal domain Methyltransf_3 PF01596.17 ORX96832.1 - 5.3e-21 74.8 0.1 6.2e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORX96832.1 - 4.1e-13 50.3 0.0 6.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX96832.1 - 0.00018 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ORX96832.1 - 0.0051 16.5 0.0 0.058 13.1 0.0 1.9 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Cons_hypoth95 PF03602.15 ORX96832.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 ORX96832.1 - 0.11 13.3 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.28 ORX96833.1 - 4.6e-12 46.9 0.3 6e-12 46.5 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Defensin_propep PF00879.18 ORX96833.1 - 0.13 12.5 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 Defensin propeptide TusA PF01206.17 ORX96859.1 - 2.7e-18 65.6 0.1 3.6e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Sulfurtransferase TusA DJ-1_PfpI PF01965.24 ORX96860.1 - 4.6e-06 26.5 0.0 7.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_6 PF12697.7 ORX96861.1 - 2e-06 28.6 0.0 2.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX96861.1 - 0.014 14.6 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4385 PF14328.6 ORX96862.1 - 6.5e-66 220.9 0.5 7.4e-66 220.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) VirE PF05272.11 ORX96862.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E ABC2_membrane PF01061.24 ORX96864.1 - 1.6e-46 158.4 19.3 3e-46 157.5 19.3 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORX96864.1 - 2.4e-18 67.0 0.0 5.5e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 ORX96864.1 - 5.2e-07 29.1 22.1 5.2e-07 29.1 22.1 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORX96864.1 - 0.03 14.1 0.0 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 ORX96864.1 - 0.048 12.9 15.7 0.059 12.6 13.0 2.3 3 0 0 3 3 3 0 ABC-2 family transporter protein SMC_N PF02463.19 ORX96864.1 - 0.3 10.5 0.5 0.6 9.5 0.1 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain GTP_EFTU_D3 PF03143.17 ORX96865.1 - 0.016 15.5 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Pkinase PF00069.25 ORX96866.1 - 1.6e-25 90.0 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96866.1 - 4.3e-12 45.9 0.0 5.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX96866.1 - 9.6e-08 31.2 0.1 1.4e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX96866.1 - 0.0026 17.7 0.0 0.69 9.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cupin_8 PF13621.6 ORX96867.1 - 3e-76 256.5 1.5 3.8e-76 256.2 1.5 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORX96867.1 - 0.00098 19.5 1.1 0.6 10.6 0.6 3.3 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 ORX96867.1 - 0.034 13.6 0.5 0.11 12.0 0.2 1.9 2 1 1 3 3 3 0 Cupin superfamily protein Cupin_2 PF07883.11 ORX96867.1 - 0.11 12.3 0.1 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Cupin domain Mem_trans PF03547.18 ORX96868.1 - 1.4e-48 165.2 10.6 2.5e-48 164.4 10.6 1.4 1 1 0 1 1 1 1 Membrane transport protein RasGAP PF00616.19 ORX96869.1 - 1.5e-17 64.0 0.0 3.8e-11 43.1 0.0 2.9 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Ion_trans_N PF08412.10 ORX96869.1 - 0.11 12.1 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal Ribosomal_S5 PF00333.20 ORX96870.1 - 6e-29 99.8 0.5 1.5e-28 98.5 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORX96870.1 - 4.6e-25 86.9 0.0 7.8e-25 86.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORX96870.1 - 1.3 9.6 9.3 2.5 8.7 9.3 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Nefa_Nip30_N PF10187.9 ORX96871.1 - 5.7e-23 81.3 14.1 6.5e-23 81.1 14.1 1.0 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 TAF8_C PF10406.9 ORX96871.1 - 9.6 6.9 7.1 0.76 10.4 0.3 2.3 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term Ssu72 PF04722.13 ORX96872.1 - 3.3e-86 287.7 0.0 3.7e-86 287.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein CLU PF13236.6 ORX96873.1 - 4.8e-84 281.6 0.0 1.1e-83 280.5 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 ORX96873.1 - 1.1e-48 165.5 0.1 2.9e-48 164.2 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 ORX96873.1 - 2.5e-27 95.0 13.6 5.8e-11 42.5 0.0 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 ORX96873.1 - 1.3e-23 82.1 0.4 1.1e-05 25.2 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat CLU_N PF15044.6 ORX96873.1 - 1.6e-20 73.2 1.3 3.5e-20 72.2 0.2 2.2 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 ORX96873.1 - 6.1e-07 29.2 3.9 0.014 15.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 ORX96873.1 - 3.6e-05 23.8 0.0 9.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 ORX96873.1 - 0.00064 19.7 7.3 10 6.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX96873.1 - 0.0015 18.2 2.9 22 5.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX96873.1 - 0.0021 17.5 0.3 0.0046 16.4 0.3 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 ORX96873.1 - 0.0022 17.9 2.1 31 4.9 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORX96873.1 - 0.079 13.6 1.2 30 5.6 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat ubiquitin PF00240.23 ORX96873.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family RBD PF02196.15 ORX96873.1 - 0.12 12.4 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Raf-like Ras-binding domain TPR_17 PF13431.6 ORX96873.1 - 0.16 12.4 0.6 1.1e+02 3.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2235 PF09994.9 ORX96874.1 - 1.7e-80 270.5 0.0 2.1e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Thi4 PF01946.17 ORX96876.1 - 6.2e-106 352.9 2.0 7.2e-106 352.7 2.0 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORX96876.1 - 2.2e-14 53.8 4.1 3.1e-09 36.9 1.2 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX96876.1 - 4.2e-09 36.5 0.1 1.1e-08 35.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORX96876.1 - 5.8e-09 35.5 3.3 6e-06 25.6 1.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORX96876.1 - 1.2e-06 28.0 0.4 2.5e-06 26.9 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX96876.1 - 8.5e-06 24.7 1.5 7.5e-05 21.6 0.8 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 ORX96876.1 - 1e-05 24.9 0.1 1.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORX96876.1 - 3.4e-05 23.1 1.1 7.3e-05 22.0 0.6 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 ORX96876.1 - 9.2e-05 22.0 0.3 9.2e-05 22.0 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX96876.1 - 0.00012 21.4 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX96876.1 - 0.00015 21.8 0.2 0.00065 19.7 0.2 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORX96876.1 - 0.0044 17.5 0.6 0.0044 17.5 0.6 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORX96876.1 - 0.0056 16.0 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 ORX96876.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ORX96876.1 - 0.099 11.7 3.0 0.12 11.5 1.5 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ORX96876.1 - 0.1 11.5 0.8 0.34 9.7 0.3 1.8 1 1 0 2 2 2 0 Tryptophan halogenase WD40 PF00400.32 ORX96877.1 - 0.00083 20.1 2.6 0.92 10.5 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 ORX96877.1 - 0.015 14.6 0.1 0.3 10.4 0.0 2.7 1 1 2 3 3 3 0 WD40-like domain RAB3GAP2_N PF14655.6 ORX96877.1 - 0.048 12.9 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 ORX96877.1 - 0.17 11.9 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat Pkinase PF00069.25 ORX96878.1 - 3.5e-76 256.0 0.0 4e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX96878.1 - 1.6e-33 116.1 0.0 2e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX96878.1 - 7.2e-05 21.9 0.0 0.00086 18.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORX96878.1 - 0.00022 21.3 0.0 0.0023 17.9 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORX96878.1 - 0.00037 19.9 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 ORX96878.1 - 0.0069 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 ORX96878.1 - 0.022 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family zf-C2H2 PF00096.26 ORX96879.1 - 8.2e-21 73.2 29.1 3.1e-06 27.3 2.9 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX96879.1 - 3.2e-17 62.1 24.9 9.6e-08 32.1 1.2 4.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX96879.1 - 4.1e-12 45.8 24.8 0.0074 17.0 2.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX96879.1 - 2.6e-05 24.4 9.7 0.41 11.0 0.9 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX96879.1 - 0.0002 21.6 13.1 0.054 13.9 1.2 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 ORX96879.1 - 0.013 15.7 10.9 0.36 11.2 2.2 3.2 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ORX96879.1 - 3.2 8.5 6.3 2.9 8.6 0.2 3.2 2 1 2 4 4 4 0 FOXP coiled-coil domain GAGA PF09237.11 ORX96879.1 - 4.7 7.1 9.0 0.55 10.1 2.9 2.3 1 1 2 3 3 3 0 GAGA factor UBZ_FAAP20 PF15750.5 ORX96879.1 - 7.1 6.7 7.1 0.86 9.6 1.7 2.2 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger MS_channel PF00924.18 ORX96880.1 - 1.8e-19 70.1 0.2 2.4e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 ORX96880.1 - 2.9e-06 26.4 0.7 8.5e-06 25.0 0.7 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORX96880.1 - 5.3e-05 22.8 0.3 0.00016 21.4 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ORX96880.1 - 0.00039 19.8 0.6 0.0011 18.4 0.6 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORX96880.1 - 0.011 16.2 0.1 0.038 14.5 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair Gcn1_N PF12074.8 ORX96881.1 - 2.1e-66 224.7 8.6 6.1e-66 223.1 0.1 6.0 9 1 1 10 10 10 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 ORX96881.1 - 5.4e-59 191.1 19.1 0.00013 21.9 0.0 23.0 24 0 0 24 24 22 10 HEAT repeat HEAT_2 PF13646.6 ORX96881.1 - 8.8e-43 144.6 14.6 2.7e-05 24.5 0.0 16.2 13 3 2 16 16 16 8 HEAT repeats HEAT_EZ PF13513.6 ORX96881.1 - 1.1e-42 144.0 21.2 0.00014 22.3 0.0 21.8 22 4 4 26 26 22 8 HEAT-like repeat Cnd1 PF12717.7 ORX96881.1 - 5.2e-30 104.6 5.4 0.00013 22.0 0.0 10.9 8 2 2 10 10 10 7 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORX96881.1 - 5.7e-25 88.2 0.2 6.3e-06 25.9 0.0 8.3 8 1 1 9 9 9 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 ORX96881.1 - 7.9e-20 71.3 0.1 0.0092 16.6 0.0 10.6 11 2 2 13 13 10 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORX96881.1 - 2.8e-13 49.3 12.6 0.011 14.3 2.8 8.6 9 2 0 9 9 9 4 Adaptin N terminal region UME PF08064.13 ORX96881.1 - 1.8e-12 47.0 13.5 0.87 9.5 0.0 11.4 8 3 4 12 12 12 3 UME (NUC010) domain DUF3385 PF11865.8 ORX96881.1 - 2.2e-11 43.9 0.7 0.47 10.4 0.0 8.8 9 1 1 10 10 8 1 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.7 ORX96881.1 - 2e-08 34.4 4.2 0.41 11.0 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion ParcG PF10274.9 ORX96881.1 - 5.1e-08 33.3 3.7 2 8.5 0.0 7.6 7 2 2 9 9 9 3 Parkin co-regulated protein Ecm29 PF13001.7 ORX96881.1 - 1.1e-06 27.6 5.0 0.0022 16.7 0.2 5.3 4 0 0 4 4 4 1 Proteasome stabiliser RIX1 PF08167.12 ORX96881.1 - 5.2e-05 23.1 0.2 5.2e-05 23.1 0.2 6.8 7 1 0 7 7 7 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 ORX96881.1 - 0.01 16.0 6.9 90 3.3 0.0 7.9 8 1 0 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 ORX96881.1 - 0.011 14.9 25.7 3.1 6.8 0.0 10.0 8 3 5 13 13 13 0 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 ORX96881.1 - 0.011 14.9 5.3 7.4 5.6 0.1 6.1 5 2 2 8 8 8 0 Dopey, N-terminal DUF4042 PF13251.6 ORX96881.1 - 0.054 13.2 0.8 28 4.4 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) IKBKB_SDD PF18397.1 ORX96881.1 - 0.069 12.4 0.3 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain TAN PF11640.8 ORX96881.1 - 0.1 12.7 0.1 1.1 9.3 0.1 2.9 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF5578 PF17741.1 ORX96881.1 - 0.15 11.5 10.6 7.5 5.9 0.0 6.4 8 0 0 8 8 8 0 Family of unknown function (DUF5578) Mito_carr PF00153.27 ORX96882.1 - 2e-71 236.0 5.5 1.2e-24 86.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Endosulfine PF04667.17 ORX96883.1 - 6.4e-29 99.9 0.6 9.7e-29 99.3 0.6 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region SSrecog PF03531.14 ORX96884.1 - 3.3e-31 107.0 0.2 3.8e-30 103.6 0.3 2.6 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 ORX96884.1 - 3.5e-30 104.3 0.0 5.8e-26 90.7 0.0 2.7 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 ORX96884.1 - 1.1e-29 102.6 0.0 3.3e-28 97.9 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Synaptobrevin PF00957.21 ORX96885.1 - 1.2 8.9 4.9 0.51 10.2 2.1 1.7 2 0 0 2 2 2 0 Synaptobrevin TPR_2 PF07719.17 ORX96886.1 - 4.6e-36 120.0 3.8 3.1e-06 26.9 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORX96886.1 - 2.5e-34 115.7 5.9 6.5e-08 32.1 0.0 8.8 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX96886.1 - 5.3e-32 109.9 18.8 3.1e-27 94.6 0.3 5.8 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORX96886.1 - 6.9e-25 85.1 10.2 8.5e-06 25.6 0.2 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX96886.1 - 3.3e-22 78.6 15.9 7.9e-12 45.3 0.2 8.4 4 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORX96886.1 - 8.7e-17 61.4 1.9 0.28 11.7 0.0 7.2 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORX96886.1 - 2.9e-16 58.9 8.1 0.00016 21.3 0.0 6.7 5 1 1 6 6 6 4 TPR repeat TPR_14 PF13428.6 ORX96886.1 - 7.8e-16 57.4 0.7 0.21 12.5 0.0 7.0 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORX96886.1 - 4.2e-15 56.1 3.1 6.3e-05 23.6 0.0 6.0 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORX96886.1 - 4.4e-15 54.5 8.8 0.0011 18.9 0.0 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORX96886.1 - 1.5e-13 50.1 6.7 0.0034 17.2 0.0 6.4 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORX96886.1 - 1.1e-10 41.1 0.5 9.7 6.8 0.0 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX96886.1 - 1.7e-07 31.4 9.8 1.6 9.5 0.1 7.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORX96886.1 - 1.3e-06 28.0 0.6 0.016 14.6 0.0 4.1 3 2 1 4 4 4 2 MalT-like TPR region TPR_15 PF13429.6 ORX96886.1 - 2.2e-06 27.1 0.5 0.16 11.1 0.0 3.9 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX96886.1 - 4.9e-05 23.4 0.1 3.8 7.7 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat PPR PF01535.20 ORX96886.1 - 0.0036 17.5 3.4 3.4 8.1 0.0 4.7 6 0 0 6 6 4 1 PPR repeat TPR_21 PF09976.9 ORX96886.1 - 0.0036 17.0 4.3 0.15 11.7 0.0 4.5 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 ORX96886.1 - 0.0038 17.2 4.7 32 4.7 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 ORX96886.1 - 0.0083 16.2 4.2 21 5.3 0.1 5.4 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 ORX96886.1 - 0.038 13.4 0.1 6.1 6.4 0.0 3.4 2 0 0 2 2 2 0 SHNi-TPR SNAP PF14938.6 ORX96886.1 - 0.049 13.1 9.6 3.5 7.0 0.1 4.5 5 0 0 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 ORX96886.1 - 0.067 13.9 0.0 12 6.9 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORX96886.1 - 0.23 11.5 13.2 3.1 7.9 0.0 5.2 7 0 0 7 7 4 0 Fis1 C-terminal tetratricopeptide repeat His_Phos_2 PF00328.22 ORX96887.1 - 4.8e-29 101.9 0.0 1.9e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tfb2 PF03849.14 ORX96915.1 - 4.9e-146 486.3 3.5 5.8e-146 486.0 3.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ORX96915.1 - 4e-26 91.2 0.6 1.1e-25 89.9 0.6 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ORX96915.1 - 0.00054 20.1 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 ORX96916.1 - 2e-21 76.3 0.8 2.9e-21 75.8 0.2 1.6 2 0 0 2 2 2 1 SPRY domain UDPG_MGDP_dh_N PF03721.14 ORX96917.1 - 8.9e-62 208.0 0.0 1.6e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 ORX96917.1 - 6.7e-38 129.3 0.3 5.1e-36 123.3 0.3 3.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 ORX96917.1 - 6e-30 103.3 0.3 1.3e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 ORX96917.1 - 0.0044 17.6 0.2 2.4 8.8 0.0 3.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ORX96917.1 - 0.019 14.9 0.0 0.39 10.6 0.0 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORX96917.1 - 0.027 14.6 0.0 0.32 11.2 0.0 2.5 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ORX96917.1 - 0.036 14.3 0.1 0.14 12.4 0.0 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 ORX96917.1 - 0.071 13.1 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-CCCH PF00642.24 ORX96918.1 - 3.1e-19 68.4 19.1 7.8e-10 38.4 3.6 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) W2 PF02020.18 ORX96918.1 - 9.8e-18 64.1 0.5 2e-17 63.1 0.5 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon zf_CCCH_4 PF18345.1 ORX96918.1 - 2e-08 34.0 12.6 0.00027 20.9 1.4 2.5 2 0 0 2 2 2 2 Zinc finger domain NUDIX PF00293.28 ORX96918.1 - 1e-07 32.0 0.0 3.4e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain zf-CCCH_4 PF18044.1 ORX96918.1 - 1.7e-05 24.5 16.6 0.0065 16.3 2.4 2.7 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORX96918.1 - 0.00028 21.3 13.2 0.059 13.9 2.1 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORX96918.1 - 0.009 16.7 5.4 0.18 12.5 0.3 2.5 1 1 1 2 2 2 2 Torus domain HHH_7 PF14635.6 ORX96918.1 - 0.035 14.5 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kinesin PF00225.23 ORX96919.1 - 1.5e-94 316.6 0.2 2.5e-94 315.9 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX96919.1 - 3.9e-17 62.6 0.0 3.2e-16 59.6 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding SAM_1 PF00536.30 ORX96919.1 - 4.2e-07 30.3 0.0 8.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORX96919.1 - 3.3e-06 27.1 0.0 7.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) COX7a PF02238.15 ORX96920.1 - 1.7e-16 60.3 0.2 2e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII MCLC PF05934.11 ORX96920.1 - 0.082 11.6 0.0 0.082 11.6 0.0 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Tcp11 PF05794.13 ORX96921.1 - 0.1 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 T-complex protein 11 Atx10homo_assoc PF09759.9 ORX96922.1 - 1.8e-38 130.6 0.1 4.2e-38 129.4 0.1 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 ORX96922.1 - 0.0087 16.1 0.9 0.85 9.6 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORX96922.1 - 0.036 12.6 0.1 0.11 11.0 0.0 1.8 2 0 0 2 2 2 0 Adaptin N terminal region Ribosomal_L29e PF01779.17 ORX96923.1 - 1.5e-24 86.0 11.5 2e-24 85.6 11.5 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Metallophos PF00149.28 ORX96924.1 - 9.4e-39 134.0 0.1 1.2e-38 133.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX96924.1 - 3.8e-23 81.7 0.2 9e-23 80.5 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L23eN PF03939.13 ORX96925.1 - 5.2e-24 84.2 7.6 8.8e-24 83.5 7.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORX96925.1 - 1.2e-14 54.4 2.0 1.3e-13 51.1 0.4 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Vps5 PF09325.10 ORX96926.1 - 9.5e-67 225.0 9.3 1.3e-66 224.6 9.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORX96926.1 - 4e-26 91.2 0.2 1.6e-23 82.8 0.0 2.6 2 0 0 2 2 2 2 PX domain BAR_3_WASP_bdg PF10456.9 ORX96926.1 - 0.035 13.6 0.8 1.4 8.3 0.8 2.2 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DivIC PF04977.15 ORX96926.1 - 0.043 13.6 2.0 0.47 10.3 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.20 ORX96926.1 - 3.6 7.6 0.0 3.6 7.6 0.0 3.6 3 1 1 4 4 4 0 Prefoldin subunit DUF5427 PF10310.9 ORX96927.1 - 0.0093 15.0 7.6 0.011 14.8 7.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Spore_coat_CotO PF14153.6 ORX96927.1 - 0.0094 15.9 7.1 0.016 15.2 7.1 1.3 1 0 0 1 1 1 1 Spore coat protein CotO DUF5507 PF17612.2 ORX96927.1 - 0.039 13.7 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5507) Podoplanin PF05808.11 ORX96927.1 - 0.05 13.7 3.0 0.072 13.2 3.0 1.2 1 0 0 1 1 1 0 Podoplanin RP-C_C PF11800.8 ORX96927.1 - 0.17 12.0 3.6 0.2 11.7 3.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Zip PF02535.22 ORX96927.1 - 0.61 9.2 1.4 0.62 9.2 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ORX96927.1 - 0.89 8.2 2.1 0.91 8.2 2.1 1.1 1 0 0 1 1 1 0 Presenilin Exo_endo_phos PF03372.23 ORX96928.1 - 4.9e-25 88.4 0.2 4.7e-24 85.2 0.2 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 ORX96928.1 - 3.5e-13 49.1 30.0 5.6e-07 29.2 7.3 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORX96928.1 - 2.9e-11 43.4 10.4 2.2e-08 34.2 1.9 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX96928.1 - 0.018 15.5 8.2 0.76 10.6 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 ORX96928.1 - 0.098 12.8 6.8 0.35 11.0 0.6 3.1 3 0 0 3 3 3 0 Leucine Rich repeat CoaE PF01121.20 ORX96929.1 - 1.4e-60 204.0 0.0 1.7e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 ORX96929.1 - 8.8e-08 32.8 0.0 1.6e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORX96929.1 - 1.6e-05 25.2 0.0 3.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORX96929.1 - 0.04 14.1 0.0 0.22 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 ORX96929.1 - 0.043 13.9 0.1 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase CLP1_P PF16575.5 ORX96929.1 - 0.082 12.7 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_17 PF13207.6 ORX96929.1 - 0.096 13.1 0.2 4.5 7.7 0.1 2.7 1 1 1 2 2 2 0 AAA domain PPR_2 PF13041.6 ORX96930.1 - 5.5e-70 231.4 15.3 7.3e-16 58.1 0.0 9.7 3 2 7 10 10 10 8 PPR repeat family PPR PF01535.20 ORX96930.1 - 2.6e-49 162.1 8.5 1e-07 31.7 0.1 10.7 11 0 0 11 11 10 9 PPR repeat PPR_3 PF13812.6 ORX96930.1 - 5e-47 157.8 10.4 1.2e-13 50.9 0.1 7.8 3 2 6 9 9 9 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX96930.1 - 5.3e-45 150.8 0.1 4.6e-08 32.6 0.0 8.5 8 0 0 8 8 8 7 PPR repeat PPR_long PF17177.4 ORX96930.1 - 1.2e-28 100.0 0.4 3.9e-10 39.5 0.0 4.3 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX96930.1 - 7.5e-05 23.2 0.0 36 5.5 0.0 7.4 6 2 3 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORX96930.1 - 0.00056 19.2 0.2 0.01 15.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX96930.1 - 0.0059 16.7 1.4 28 5.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat B12-binding_2 PF02607.17 ORX96930.1 - 0.017 15.6 0.1 3 8.4 0.0 3.7 4 2 1 5 5 4 0 B12 binding domain Phage_ABA_S PF18066.1 ORX96930.1 - 0.021 15.5 0.9 14 6.5 0.1 4.1 3 2 2 5 5 5 0 Phage ABA sandwich domain AEP1 PF17049.5 ORX96930.1 - 0.039 13.0 0.4 2.6 7.0 0.2 3.4 2 1 2 4 4 4 0 ATPase expression protein 1 ECSIT PF06239.11 ORX96930.1 - 0.12 11.5 2.0 12 4.9 0.1 3.6 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway CTP_transf_like PF01467.26 ORX96931.1 - 1.1e-31 110.0 0.0 1.8e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 ORX96931.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5639) DUF5499 PF17603.2 ORX96931.1 - 0.089 13.4 0.3 0.31 11.7 0.3 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5499) Peptidase_S8 PF00082.22 ORX96932.1 - 5.9e-27 94.7 18.8 3.7e-26 92.1 18.8 2.1 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX96932.1 - 7e-07 29.8 0.2 1.3e-06 29.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX96932.1 - 0.065 13.3 0.5 0.11 12.5 0.5 1.3 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX96933.1 - 5.3e-25 88.3 13.7 1.2e-24 87.2 13.6 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX96933.1 - 8.4e-07 29.6 1.0 1.3e-06 29.0 0.2 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX96933.1 - 0.062 13.4 0.7 0.12 12.5 0.7 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX96934.1 - 3.7e-37 128.2 18.9 7.7e-37 127.2 18.9 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX96934.1 - 0.0071 17.0 0.1 0.013 16.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Fibrillarin_2 PF10113.9 ORX96934.1 - 0.12 11.0 0.4 0.17 10.5 0.4 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Peptidase_S8 PF00082.22 ORX96935.1 - 8.7e-37 127.0 18.7 1.8e-36 125.9 18.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX96935.1 - 2.3e-05 25.0 0.1 5e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 ORX96936.1 - 2.7e-36 125.4 18.7 5.5e-36 124.3 18.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX96936.1 - 0.0042 17.7 0.3 0.11 13.2 0.0 2.3 1 1 1 2 2 2 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 ORX96937.1 - 1.4e-14 54.1 10.3 4.2e-09 36.1 4.0 2.5 1 1 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 ORX96937.1 - 0.12 13.0 0.1 0.41 11.3 0.1 1.9 1 1 0 1 1 1 0 Peptidase inhibitor I9 TGF_beta_GS PF08515.12 ORX96937.1 - 1.8 8.1 7.0 13 5.4 0.8 2.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Serglycin PF04360.12 ORX96937.1 - 2.4 8.1 6.4 12 5.9 0.4 2.3 1 1 1 2 2 2 0 Serglycin Hydrolase_4 PF12146.8 ORX96938.1 - 3.8e-51 173.7 0.0 4.4e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX96938.1 - 1.2e-17 64.4 0.8 3.9e-13 49.6 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX96938.1 - 7.3e-14 52.9 0.0 1.1e-13 52.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORX96938.1 - 1.8e-06 27.6 1.7 5.7e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORX96938.1 - 2.8e-05 24.0 0.3 1.2 8.9 0.1 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 ORX96938.1 - 0.0011 17.7 0.3 0.0015 17.3 0.3 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein RMMBL PF07521.12 ORX96938.1 - 0.011 15.7 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain DLH PF01738.18 ORX96938.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family CBM_19 PF03427.13 ORX96939.1 - 0.049 13.6 2.8 0.086 12.8 2.8 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DP PF08781.10 ORX96939.1 - 0.057 13.3 0.1 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 Transcription factor DP Baculo_VP91_N PF08475.10 ORX96939.1 - 0.58 9.8 4.5 1.3 8.6 4.5 1.7 1 1 0 1 1 1 0 Viral capsid protein 91 N-terminal UPF0257 PF06788.13 ORX96940.1 - 3.5e-06 27.0 0.0 53 3.5 0.0 5.8 6 0 0 6 6 6 0 Uncharacterised protein family (UPF0257) FHA_2 PF17913.1 ORX96940.1 - 0.00061 20.0 0.1 2.3e+02 2.1 0.0 5.6 6 0 0 6 6 6 0 FHA domain DUF1513 PF07433.11 ORX96940.1 - 0.0057 15.8 7.9 15 4.5 0.1 5.7 6 0 0 6 6 6 1 Protein of unknown function (DUF1513) DHH PF01368.20 ORX96940.1 - 2.8 8.2 5.6 13 6.1 0.0 4.2 6 0 0 6 6 6 0 DHH family Cytidylate_kin2 PF13189.6 ORX96940.1 - 8.3 6.5 17.1 58 3.7 0.0 5.7 6 0 0 6 6 6 0 Cytidylate kinase-like family CBM_19 PF03427.13 ORX96941.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) PTR2 PF00854.21 ORX96943.1 - 1.4e-80 271.1 9.6 2.1e-80 270.5 9.6 1.2 1 0 0 1 1 1 1 POT family PTR2 PF00854.21 ORX96944.1 - 4.2e-82 276.1 8.2 6.1e-82 275.6 8.2 1.2 1 0 0 1 1 1 1 POT family Baculo_gp41 PF04700.12 ORX96944.1 - 0.2 11.4 0.2 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region SUR7 PF06687.12 ORX96944.1 - 0.73 9.4 8.5 1.6 8.3 3.5 2.4 2 0 0 2 2 2 0 SUR7/PalI family PTR2 PF00854.21 ORX96945.1 - 4.3e-82 276.1 9.5 6.7e-82 275.4 9.5 1.2 1 0 0 1 1 1 1 POT family DUF3980 PF13140.6 ORX96945.1 - 0.68 10.4 4.7 0.21 12.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) PTR2 PF00854.21 ORX96946.1 - 2.7e-74 250.4 18.4 5e-39 134.3 1.6 2.2 1 1 1 2 2 2 2 POT family DUF3980 PF13140.6 ORX96946.1 - 0.56 10.7 4.0 0.2 12.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Pyr_redox_2 PF07992.14 ORX96947.1 - 2e-39 135.6 0.1 3.6e-39 134.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 ORX96947.1 - 7.5e-24 83.7 0.0 4e-23 81.3 0.0 2.3 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 ORX96947.1 - 1.1e-20 73.8 7.2 1.8e-16 60.2 3.9 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 ORX96947.1 - 3.2e-18 65.7 0.0 6.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 ORX96947.1 - 7.6e-12 45.6 3.3 3.2e-10 40.4 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 ORX96947.1 - 2.7e-11 43.2 0.0 5.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 ORX96947.1 - 1.8e-08 34.2 0.1 4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 ORX96947.1 - 9.1e-08 31.9 0.0 4.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain FAD_binding_2 PF00890.24 ORX96947.1 - 0.002 17.3 1.0 0.072 12.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORX96947.1 - 0.0044 16.4 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORX96947.1 - 0.026 13.6 0.3 1.3 8.0 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORX96947.1 - 0.027 14.7 0.1 0.068 13.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX96947.1 - 0.06 12.6 0.0 2.7 7.2 0.1 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORX96948.1 - 9e-40 136.7 0.1 1.6e-39 135.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 ORX96948.1 - 7.7e-24 83.6 0.0 4e-23 81.3 0.0 2.3 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 ORX96948.1 - 1e-20 73.8 7.2 1.7e-16 60.2 3.9 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 ORX96948.1 - 3.3e-18 65.7 0.0 6.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ORX96948.1 - 2.6e-11 43.2 0.0 5.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.27 ORX96948.1 - 6.9e-11 42.5 5.9 4.9e-10 39.8 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 ORX96948.1 - 1.8e-08 34.2 0.1 4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 ORX96948.1 - 7.6e-08 32.2 0.0 3.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain FAD_binding_2 PF00890.24 ORX96948.1 - 0.0021 17.2 1.1 0.072 12.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORX96948.1 - 0.0068 15.7 0.1 0.02 14.2 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ORX96948.1 - 0.032 14.5 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX96948.1 - 0.13 11.4 1.3 0.63 9.1 0.4 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkH PF02386.16 ORX96978.1 - 2.4e-96 323.2 16.5 2.9e-92 309.7 9.8 2.0 2 0 0 2 2 2 2 Cation transport protein G-alpha PF00503.20 ORX96979.1 - 9.3e-119 396.7 0.3 1.1e-118 396.5 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX96979.1 - 7.3e-14 51.6 0.7 4.3e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORX96979.1 - 0.00076 19.3 0.5 0.0032 17.2 0.2 2.1 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORX96979.1 - 0.0066 15.8 5.3 0.07 12.5 0.1 2.9 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORX96979.1 - 0.017 14.7 0.0 4.1 6.9 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.6 ORX96979.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORX96979.1 - 0.031 14.0 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORX96979.1 - 0.045 14.0 0.3 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 ORX96979.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 ORX96979.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ORX96979.1 - 0.13 12.3 0.1 8.4 6.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4062 PF13271.6 ORX96980.1 - 0.14 12.5 0.1 0.43 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Fasciclin PF02469.22 ORX96982.1 - 2.7e-51 173.1 0.0 6.9e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Sel1 PF08238.12 ORX96983.1 - 3.6e-23 81.5 13.5 7.6e-08 32.8 2.2 4.4 4 1 0 4 4 4 4 Sel1 repeat DEAD PF00270.29 ORX96984.1 - 5.1e-20 72.0 0.1 9.3e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX96984.1 - 1e-18 67.7 0.0 4.9e-14 52.6 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORX96984.1 - 5.5e-11 43.0 2.5 5.5e-11 43.0 2.5 2.2 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 ORX96984.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RhoGAP PF00620.27 ORX96985.1 - 1e-36 126.0 0.0 1.3e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain FAM184 PF15665.5 ORX96986.1 - 0.00031 20.6 36.1 0.00031 20.6 36.1 7.0 4 1 2 7 7 7 5 Family with sequence similarity 184, A and B RVT_connect PF06815.13 ORX96986.1 - 0.033 14.5 1.1 0.24 11.7 0.1 3.0 2 1 1 3 3 3 0 Reverse transcriptase connection domain PB1 PF00564.24 ORX96988.1 - 1.1e-08 34.9 0.5 0.00024 21.0 0.1 2.5 2 0 0 2 2 2 2 PB1 domain PX PF00787.24 ORX96988.1 - 0.0016 18.4 0.0 0.0051 16.8 0.0 1.9 1 0 0 1 1 1 1 PX domain LapA_dom PF06305.11 ORX96989.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM190 PF15431.6 ORX96989.1 - 0.035 14.3 0.5 0.035 14.3 0.5 1.6 2 0 0 2 2 2 0 Transmembrane protein 190 DUF4381 PF14316.6 ORX96989.1 - 0.043 14.1 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1673 PF07895.11 ORX96989.1 - 0.08 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2207 PF09972.9 ORX96989.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF948 PF06103.11 ORX96989.1 - 0.18 12.1 0.2 11 6.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Exo_endo_phos PF03372.23 ORX96990.1 - 1.3e-10 41.3 0.0 5.3e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MBOAT_2 PF13813.6 ORX96991.1 - 5.1e-10 39.5 2.4 1.1e-09 38.4 2.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LrgB PF04172.16 ORX96993.1 - 7.4e-39 133.5 8.1 8.8e-39 133.2 8.1 1.0 1 0 0 1 1 1 1 LrgB-like family CBM9_1 PF06452.11 ORX96994.1 - 5e-08 33.1 0.7 4e-07 30.1 0.7 2.0 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like CaMBD PF02888.16 ORX96995.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Calmodulin binding domain Pet127 PF08634.10 ORX96995.1 - 0.021 14.3 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 SNF2_N PF00176.23 ORX96996.1 - 7.8e-09 34.7 0.1 1.5e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain IL4_i_Ig PF18258.1 ORX96996.1 - 0.018 15.2 0.1 8.1 6.7 0.0 3.2 3 0 0 3 3 3 0 Interleukin-4 inducing immunoglobulin-binding domain Kelch_5 PF13854.6 ORX96996.1 - 0.038 14.0 0.6 5.5 7.1 0.1 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 ORX96996.1 - 0.073 13.4 2.9 30 5.0 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain DnaB_C PF03796.15 ORX96996.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Kelch_6 PF13964.6 ORX96996.1 - 0.25 11.7 0.7 32 5.0 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Glyco_hydro_18 PF00704.28 ORX97030.1 - 4.9e-24 85.6 1.0 3.3e-23 82.9 1.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX97030.1 - 0.0025 18.3 28.3 0.0064 17.0 6.0 3.4 3 0 0 3 3 3 2 Carbohydrate binding domain Rieske PF00355.26 ORX97032.1 - 6.8e-13 48.4 0.2 8.9e-13 48.0 0.2 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ORX97032.1 - 4.6e-09 36.2 0.0 5.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GPI-anchored PF10342.9 ORX97033.1 - 1e-11 45.4 1.1 1e-11 45.4 1.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mfa2 PF08842.10 ORX97033.1 - 0.028 14.0 0.4 0.036 13.7 0.4 1.1 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 Myb_DNA-binding PF00249.31 ORX97034.1 - 2.2e-24 85.4 0.6 3.9e-11 43.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX97034.1 - 3e-18 65.8 4.6 3.8e-10 39.9 0.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORX97034.1 - 0.034 14.5 4.5 4.3 7.8 0.1 3.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain FeoB_C PF07664.12 ORX97034.1 - 0.11 12.3 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus Myb_DNA-bind_7 PF15963.5 ORX97034.1 - 0.14 12.1 0.0 1.7 8.6 0.0 2.2 2 1 0 2 2 2 0 Myb DNA-binding like GPI-anchored PF10342.9 ORX97035.1 - 3.5e-12 46.9 2.2 3.5e-12 46.9 2.2 3.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SBDS PF01172.18 ORX97036.1 - 1.9e-17 63.1 0.2 2.2e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RasGAP PF00616.19 ORX97037.1 - 1.1e-60 204.9 0.0 3.4e-60 203.3 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORX97037.1 - 3.2e-35 121.3 3.7 1.3e-34 119.2 0.5 2.6 2 0 0 2 2 2 1 RasGAP C-terminus DUF4047 PF13256.6 ORX97037.1 - 0.019 15.2 0.2 0.04 14.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) YabA PF06156.13 ORX97037.1 - 0.025 15.2 5.3 3.7 8.2 0.6 2.9 2 0 0 2 2 2 0 Initiation control protein YabA EIAV_Rev PF11129.8 ORX97037.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus DUF4393 PF14337.6 ORX97037.1 - 0.21 11.3 4.4 5 6.9 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4393) ADIP PF11559.8 ORX97037.1 - 0.29 11.2 9.6 2.5 8.2 0.5 3.3 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding CASP_C PF08172.12 ORX97037.1 - 0.33 10.3 3.5 0.15 11.4 0.5 1.8 2 0 0 2 2 2 0 CASP C terminal bZIP_2 PF07716.15 ORX97038.1 - 0.0064 16.6 19.9 0.0064 16.6 19.9 2.5 1 1 1 2 2 2 1 Basic region leucine zipper FAM72 PF14976.6 ORX97039.1 - 8.9e-27 94.0 2.9 1.1e-26 93.8 2.9 1.1 1 0 0 1 1 1 1 FAM72 protein Sprouty PF05210.13 ORX97039.1 - 0.039 14.3 6.9 0.085 13.3 6.9 1.6 1 1 0 1 1 1 0 Sprouty protein (Spry) Yippee-Mis18 PF03226.14 ORX97039.1 - 2.3 8.4 9.7 14 5.9 9.7 2.2 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PAP2 PF01569.21 ORX97041.1 - 4.6e-32 110.6 0.4 4.6e-32 110.6 0.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF5510 PF17629.2 ORX97041.1 - 0.027 14.4 0.1 0.078 12.9 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Frag1 PF10277.9 ORX97041.1 - 0.032 13.8 0.1 0.08 12.5 0.0 1.7 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family RseC_MucC PF04246.12 ORX97041.1 - 0.037 14.0 0.7 0.12 12.3 0.7 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Strabismus PF06638.11 ORX97041.1 - 0.052 12.2 0.4 0.073 11.7 0.4 1.1 1 0 0 1 1 1 0 Strabismus protein DUF2339 PF10101.9 ORX97041.1 - 0.066 11.8 1.2 0.14 10.7 0.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) PAP2_3 PF14378.6 ORX97041.1 - 0.07 12.8 7.7 0.56 9.9 6.6 2.4 1 1 0 1 1 1 0 PAP2 superfamily FtsX PF02687.21 ORX97041.1 - 0.56 10.7 4.4 0.51 10.8 1.0 2.5 3 0 0 3 3 3 0 FtsX-like permease family Methyltransf_23 PF13489.6 ORX97042.1 - 3.8e-13 49.6 0.0 6.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX97042.1 - 1e-07 32.5 0.0 4.4e-07 30.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX97042.1 - 1.5e-07 32.0 0.0 7.4e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX97042.1 - 1.3e-06 29.1 0.0 5.1e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX97042.1 - 2e-05 24.4 0.0 6.5e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 ORX97042.1 - 0.0042 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 ORX97042.1 - 0.049 13.0 0.0 0.95 8.8 0.0 2.3 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_7 PF03492.15 ORX97042.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_32 PF13679.6 ORX97042.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 ORX97042.1 - 0.14 11.5 0.8 0.38 10.1 0.7 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Amidohydro_1 PF01979.20 ORX97043.1 - 1.3e-12 47.7 0.0 2.6e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX97043.1 - 0.014 14.8 0.3 0.074 12.5 0.1 2.1 2 1 0 2 2 2 0 Amidohydrolase family DDE_5 PF13546.6 ORX97076.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Transferase PF02458.15 ORX97077.1 - 8.5e-41 140.0 0.0 1.2e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Transferase family DUF4553 PF15090.6 ORX97078.1 - 0.0099 14.9 2.9 0.012 14.6 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4553) Aldedh PF00171.22 ORX97079.1 - 4.2e-161 536.5 0.3 4.7e-161 536.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YCII PF03795.14 ORX97079.1 - 0.053 13.9 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 0 YCII-related domain Metallophos PF00149.28 ORX97080.1 - 7.2e-13 49.5 0.0 9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX97080.1 - 4.2e-08 33.6 0.0 5.8e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORX97080.1 - 0.00073 18.9 0.0 0.00097 18.5 0.0 1.1 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Lipase_3 PF01764.25 ORX97082.1 - 9e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX97082.1 - 0.055 13.0 0.1 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) HATPase_c_3 PF13589.6 ORX97083.1 - 3.6e-10 39.8 0.0 4.5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORX97083.1 - 5.3e-08 33.3 0.1 6.1e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pox_RNA_Pol_19 PF05320.12 ORX97083.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit MMR_HSR1 PF01926.23 ORX97084.1 - 1.8e-16 60.2 0.2 1.1e-12 48.0 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX97084.1 - 2.6e-08 33.5 0.1 5.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORX97084.1 - 1.7e-06 28.0 0.5 0.014 15.3 0.1 2.9 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORX97084.1 - 9.1e-05 22.1 0.0 9.1e-05 22.1 0.0 3.5 4 1 1 5 5 5 1 Elongation factor Tu GTP binding domain GN3L_Grn1 PF08701.11 ORX97084.1 - 0.01 15.9 8.3 0.01 15.9 8.3 2.6 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Dynamin_N PF00350.23 ORX97084.1 - 0.035 14.2 0.7 0.035 14.2 0.7 4.3 3 2 1 4 4 4 0 Dynamin family Bac_RepA_C PF18008.1 ORX97084.1 - 0.26 11.7 8.8 7.1 7.1 0.8 4.3 4 1 1 5 5 5 0 Replication initiator protein A C-terminal domain PCB_OB PF17092.5 ORX97084.1 - 0.4 11.5 3.1 0.16 12.7 0.3 1.8 2 0 0 2 2 1 0 Penicillin-binding protein OB-like domain PMC2NT PF08066.12 ORX97084.1 - 0.65 10.7 6.2 0.39 11.4 1.6 2.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF4337 PF14235.6 ORX97084.1 - 2.6 8.2 7.5 3 7.9 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2570 PF10828.8 ORX97084.1 - 7.5 6.4 13.6 0.68 9.8 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TGT PF01702.18 ORX97085.1 - 6e-146 486.1 0.0 7.3e-146 485.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase FtsH_ext PF06480.15 ORX97088.1 - 0.42 11.0 5.8 2.5 8.5 5.8 2.2 1 1 0 1 1 1 0 FtsH Extracellular GFO_IDH_MocA PF01408.22 ORX97089.1 - 5.5e-14 53.0 0.0 8.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX97089.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 ORX97090.1 - 1.2e-105 354.0 20.9 1.4e-105 353.8 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97090.1 - 3.9e-33 114.8 25.6 3.9e-33 114.8 25.6 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX97090.1 - 1.5 7.6 17.6 1.6 7.5 2.8 3.1 2 1 1 3 3 3 0 MFS_1 like family Sugar_tr PF00083.24 ORX97091.1 - 1.1e-102 344.3 25.7 1.4e-102 343.9 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97091.1 - 1.1e-31 110.1 37.8 7.5e-31 107.3 32.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORX97091.1 - 3.5 6.4 22.0 1.2 7.9 7.1 3.0 1 1 0 2 2 2 0 MFS_1 like family Y_phosphatase3 PF13350.6 ORX97092.1 - 9.3e-55 186.1 0.0 1.3e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF915 PF06028.11 ORX97092.1 - 3e-05 23.5 0.0 5.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Y_phosphatase2 PF03162.13 ORX97092.1 - 0.00031 20.4 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF3530 PF12048.8 ORX97092.1 - 0.00044 19.8 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Y_phosphatase PF00102.27 ORX97092.1 - 0.00049 19.7 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 ORX97092.1 - 0.00064 19.1 0.1 1 8.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX97092.1 - 0.0074 16.0 0.2 2.8 7.5 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold DSPc PF00782.20 ORX97092.1 - 0.0085 15.9 0.0 0.053 13.3 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_2 PF02230.16 ORX97092.1 - 0.056 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORX97092.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Myotub-related PF06602.14 ORX97092.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Oxidored_FMN PF00724.20 ORX97114.1 - 4.1e-101 338.7 0.0 4.6e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M13_N PF05649.13 ORX97115.1 - 9.5e-82 275.7 0.0 1.4e-81 275.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX97115.1 - 1.1e-61 208.1 0.0 1.6e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Thaumatin PF00314.17 ORX97116.1 - 1.6e-69 233.8 11.2 1.8e-69 233.6 11.2 1.0 1 0 0 1 1 1 1 Thaumatin family TLD PF07534.16 ORX97117.1 - 2e-36 125.3 0.2 2.2e-36 125.1 0.2 1.0 1 0 0 1 1 1 1 TLD zf-C2H2 PF00096.26 ORX97119.1 - 5.7e-08 32.8 22.3 0.0004 20.7 8.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97119.1 - 0.00016 22.2 24.4 0.0079 17.0 0.9 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX97119.1 - 0.0011 19.3 17.9 0.0062 16.9 1.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORX97119.1 - 0.019 15.0 4.0 0.019 15.0 4.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 ORX97119.1 - 0.037 14.4 5.7 0.055 13.9 1.3 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TipE PF16972.5 ORX97119.1 - 0.098 11.8 0.2 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE zf-C2H2_jaz PF12171.8 ORX97119.1 - 0.11 12.9 7.5 0.18 12.1 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NUDIX PF00293.28 ORX97120.1 - 1.7e-12 47.5 0.1 3.1e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain RNaseH_pPIWI_RE PF13032.6 ORX97120.1 - 0.092 12.6 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 RNaseH domain of pPIWI_RE zf-C2H2 PF00096.26 ORX97121.1 - 7.4e-09 35.6 15.7 0.00017 21.8 6.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97121.1 - 5.2e-06 26.7 14.1 7.3e-05 23.0 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX97121.1 - 1.7e-05 25.2 12.8 0.03 15.1 4.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORX97121.1 - 0.0056 16.6 7.0 0.54 10.3 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX97121.1 - 0.037 14.3 2.1 4.1 7.8 0.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF515 PF04415.12 ORX97121.1 - 0.87 7.9 4.8 1.2 7.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-C2H2 PF00096.26 ORX97122.1 - 1e-11 44.6 16.2 1.1e-05 25.6 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORX97122.1 - 3.3e-08 33.3 7.3 0.00017 21.5 2.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORX97122.1 - 3.9e-08 33.5 13.8 0.0011 19.6 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX97122.1 - 2.7e-06 27.6 13.5 2.3e-05 24.6 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX97122.1 - 0.0016 18.7 2.8 0.012 15.9 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX97122.1 - 0.0016 18.8 7.1 0.0043 17.4 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORX97122.1 - 0.48 10.4 13.2 1.3 9.0 0.1 2.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 ORX97122.1 - 1 9.3 7.2 1.3 9.0 1.7 2.8 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 ORX97122.1 - 4.3 7.2 14.3 0.62 9.9 1.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain ExoD PF06055.12 ORX97124.1 - 0.043 13.2 0.2 0.083 12.3 0.2 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD VERL PF11386.8 ORX97124.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin Phosphorylase PF00343.20 ORX97125.1 - 0 1071.7 0.1 0 1071.1 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate phosphorylase HA70_C PF17993.1 ORX97125.1 - 0.0031 17.6 0.3 0.063 13.3 0.2 2.5 2 0 0 2 2 2 1 Haemagglutinin 70 C-terminal domain Methyltransf_31 PF13847.6 ORX97126.1 - 3.8e-15 56.0 0.1 7.9e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX97126.1 - 3.8e-13 49.9 0.0 3.1e-12 47.0 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 ORX97126.1 - 9.6e-11 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORX97126.1 - 1.6e-09 38.3 0.2 5.7e-08 33.3 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain UPF0020 PF01170.18 ORX97126.1 - 3.7e-08 33.3 0.0 1e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 ORX97126.1 - 7.2e-08 33.1 0.3 3.6e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORX97126.1 - 9.4e-08 31.8 0.1 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 ORX97126.1 - 2e-06 27.6 0.0 6.6e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 ORX97126.1 - 2.2e-06 27.3 0.0 4.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 ORX97126.1 - 2.3e-06 27.5 0.0 5.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 ORX97126.1 - 8.8e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase PCMT PF01135.19 ORX97126.1 - 6.9e-05 22.7 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PseudoU_synth_2 PF00849.22 ORX97126.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase N6-adenineMlase PF10237.9 ORX97126.1 - 0.0014 18.5 0.6 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase Methyltransf_18 PF12847.7 ORX97126.1 - 0.003 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORX97126.1 - 0.0034 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 ORX97126.1 - 0.0079 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain rRNA_methylase PF06962.12 ORX97126.1 - 0.016 15.2 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Putative rRNA methylase Methyltransf_20 PF12147.8 ORX97126.1 - 0.02 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase N6_Mtase PF02384.16 ORX97126.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase CMAS PF02353.20 ORX97126.1 - 0.035 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 ORX97126.1 - 0.056 12.6 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase DOT1 PF08123.13 ORX97126.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.19 ORX97126.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase RNase_P_p30 PF01876.16 ORX97126.1 - 0.14 11.6 0.0 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 RNase P subunit p30 Myosin_head PF00063.21 ORX97127.1 - 5.6e-266 884.1 0.0 5.6e-266 884.1 0.0 2.4 3 0 0 3 3 3 1 Myosin head (motor domain) DIL PF01843.19 ORX97127.1 - 2.4e-22 79.2 0.8 2.4e-22 79.2 0.8 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 ORX97127.1 - 2.1e-16 58.1 32.5 2.1e-05 23.9 0.7 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.6 ORX97127.1 - 0.031 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 ORX97127.1 - 0.056 13.3 19.4 0.03 14.2 4.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AAA_16 PF13191.6 ORX97127.1 - 0.062 13.7 2.4 0.32 11.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain ATG16 PF08614.11 ORX97127.1 - 0.12 12.6 22.4 0.7 10.1 22.4 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 ORX97127.1 - 0.14 12.0 23.8 0.049 13.5 15.5 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Sec34 PF04136.15 ORX97127.1 - 0.24 11.3 10.5 0.27 11.1 3.0 2.9 1 1 1 2 2 2 0 Sec34-like family HALZ PF02183.18 ORX97127.1 - 1.3 9.4 8.4 0.52 10.6 0.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper ECH_1 PF00378.20 ORX97128.1 - 1.8e-16 60.2 0.0 4.4e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX97128.1 - 0.028 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase NAT PF04768.13 ORX97129.1 - 1.3e-49 168.1 2.3 1.3e-49 168.1 0.9 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 ORX97129.1 - 1.5e-27 96.7 0.1 5e-27 95.0 0.0 1.9 1 1 1 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 ORX97129.1 - 3.2e-27 95.4 0.0 7.5e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 ORX97129.1 - 5.7e-12 46.1 0.0 1.4e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 ORX97129.1 - 0.08 13.1 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.32 ORX97130.1 - 2.9e-17 62.7 12.7 0.0015 19.3 0.7 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX97130.1 - 0.0038 17.5 0.1 3.5 8.0 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TipE PF16972.5 ORX97130.1 - 1 8.5 6.5 1.5 7.9 6.5 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE CDC45 PF02724.14 ORX97130.1 - 1 7.6 9.8 1.2 7.3 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CD99L2 PF12301.8 ORX97130.1 - 7.7 6.8 9.7 13 6.1 9.7 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 SDA1 PF05285.12 ORX97130.1 - 9.8 5.5 21.6 14 5.0 21.6 1.1 1 0 0 1 1 1 0 SDA1 Thaumatin PF00314.17 ORX97131.1 - 6.6e-46 156.7 6.9 7.2e-46 156.5 6.9 1.0 1 0 0 1 1 1 1 Thaumatin family Tryp_inh PF17983.1 ORX97131.1 - 1.3 9.1 11.2 0.4 10.8 7.5 2.1 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 GRP PF07172.11 ORX97145.1 - 2.1 9.1 12.8 2.2 9.0 12.8 1.1 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_M66 PF10462.9 ORX97148.1 - 0.1 11.5 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Peptidase M66 Pkinase PF00069.25 ORX97149.1 - 1.1e-60 205.3 0.0 1.2e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97149.1 - 3.5e-36 124.8 0.0 4.3e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX97149.1 - 0.043 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORX97149.1 - 0.13 12.2 0.0 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family TRP_2 PF08344.11 ORX97150.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 Transient receptor ion channel II CBP_BcsO PF17037.5 ORX97150.1 - 0.049 13.8 4.3 0.11 12.6 4.3 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO OB_RNB PF08206.11 ORX97150.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Lig_chan PF00060.26 ORX97152.1 - 0.064 13.1 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel FXR_C1 PF16096.5 ORX97153.1 - 1.8 8.8 10.0 3.2 8.0 5.1 2.2 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Myticin-prepro PF10690.9 ORX97156.1 - 0.0042 17.3 0.4 0.0065 16.7 0.4 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel DJ-1_PfpI PF01965.24 ORX97161.1 - 2e-08 34.2 0.0 7.6e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX97161.1 - 0.0011 18.7 0.1 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX97161.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Latrotoxin C-terminal domain DJ-1_PfpI PF01965.24 ORX97162.1 - 6.7e-08 32.5 0.0 1.5e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX97162.1 - 0.0022 17.7 0.0 0.0065 16.2 0.0 1.7 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX97162.1 - 0.0038 17.0 0.0 0.0084 15.9 0.0 1.5 1 1 0 1 1 1 1 Latrotoxin C-terminal domain Inhibitor_I9 PF05922.16 ORX97186.1 - 1.6e-05 25.5 0.1 8.9e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 HMG_box PF00505.19 ORX97187.1 - 1.6e-25 89.3 5.0 1.6e-25 89.3 5.0 1.8 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX97187.1 - 3.5e-15 56.3 4.8 3.5e-15 56.3 4.8 1.9 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 ORX97187.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 1.9 2 1 0 2 2 2 1 HMG (high mobility group) box 5 Flavi_capsid PF01003.19 ORX97187.1 - 0.077 12.8 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C YABBY PF04690.13 ORX97187.1 - 0.81 10.2 9.1 0.09 13.3 3.8 1.8 1 1 1 2 2 2 0 YABBY protein Ccdc124 PF06244.12 ORX97187.1 - 0.93 10.1 16.8 0.057 14.0 6.5 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 TPR_8 PF13181.6 ORX97187.1 - 1.2 9.5 4.8 1.8 9.0 3.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DRMBL PF07522.14 ORX97188.1 - 5.2e-31 107.1 0.0 8.5e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 ORX97188.1 - 0.00026 20.8 0.1 0.00056 19.8 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORX97188.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORX97188.1 - 0.19 11.7 0.4 0.48 10.4 0.4 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4505 PF14956.6 ORX97189.1 - 6.5e-45 153.0 0.8 1.1e-44 152.3 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) zf-C2H2 PF00096.26 ORX97190.1 - 6.4e-21 73.6 27.7 6.5e-06 26.3 2.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97190.1 - 2.3e-20 72.0 27.5 1.4e-07 31.6 0.0 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX97190.1 - 1.2e-12 47.5 22.4 0.0073 17.1 1.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX97190.1 - 0.00085 19.9 8.2 1.8 9.3 0.4 3.9 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORX97190.1 - 0.004 17.4 8.1 4 7.8 0.5 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX97190.1 - 0.0065 16.8 9.7 7.5 7.1 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORX97190.1 - 0.007 17.0 12.1 0.014 16.1 0.8 3.2 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2H2_11 PF16622.5 ORX97190.1 - 0.0085 15.8 12.6 0.076 12.8 0.8 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 ORX97190.1 - 0.075 13.3 8.0 0.47 10.8 0.5 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 ORX97190.1 - 0.08 12.9 11.0 0.83 9.6 0.2 3.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type BolA PF01722.18 ORX97190.1 - 0.15 12.4 0.8 31 4.9 0.0 3.1 3 0 0 3 3 3 0 BolA-like protein zf-H2C2_5 PF13909.6 ORX97190.1 - 0.41 10.5 16.3 0.38 10.6 0.4 4.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 ORX97190.1 - 2.2 8.4 10.0 35 4.5 0.1 3.7 1 1 3 4 4 4 0 Aberrant zinc-finger Thymidylat_synt PF00303.19 ORX97191.1 - 1.4e-116 388.3 0.0 1.6e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Sod_Cu PF00080.20 ORX97193.1 - 2.3e-47 160.7 5.5 3e-47 160.4 5.5 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PHO4 PF01384.20 ORX97194.1 - 2.6e-108 362.1 16.0 3e-108 361.8 16.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Phage_holin_3_2 PF04550.12 ORX97194.1 - 0.0056 17.2 0.5 0.0056 17.2 0.5 3.0 4 0 0 4 4 4 1 Phage holin family 2 Methyltransf_23 PF13489.6 ORX97195.1 - 5.6e-15 55.5 0.0 7.8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX97195.1 - 2.5e-14 53.7 0.0 4.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX97195.1 - 3.1e-13 50.2 0.0 5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX97195.1 - 7.9e-06 25.7 0.0 0.00012 21.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX97195.1 - 2.7e-05 23.6 0.0 7.2e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORX97195.1 - 0.00072 20.3 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX97195.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 ORX97196.1 - 1.7e-70 237.4 0.0 2.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97196.1 - 9.9e-34 116.8 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORX97196.1 - 3.4e-09 37.3 2.9 9.5e-09 35.8 2.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 ORX97196.1 - 6.4e-08 32.2 0.0 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORX97196.1 - 0.003 17.2 0.1 2.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX97196.1 - 0.017 14.1 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORX97196.1 - 0.035 14.0 0.2 0.092 12.7 0.1 1.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family PH PF00169.29 ORX97198.1 - 5.8e-05 23.6 0.1 0.0036 17.8 0.0 2.7 2 0 0 2 2 2 1 PH domain TRAF_BIRC3_bd PF16673.5 ORX97198.1 - 0.02 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain PH_3 PF14593.6 ORX97198.1 - 0.085 13.0 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 PH domain Velvet PF11754.8 ORX97199.1 - 5.9e-60 203.3 1.5 4.2e-41 141.5 0.4 2.0 1 1 1 2 2 2 2 Velvet factor dCMP_cyt_deam_1 PF00383.23 ORX97200.1 - 1.6e-15 56.8 0.2 2.5e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORX97200.1 - 1.6e-11 44.1 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 ORX97200.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 ORX97200.1 - 0.016 15.3 0.8 0.13 12.4 0.0 2.2 1 1 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 ORX97200.1 - 0.067 13.3 0.5 0.67 10.0 0.1 2.2 2 1 0 2 2 2 0 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 ORX97200.1 - 0.11 12.5 0.8 2.9 8.0 0.8 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 ORX97200.1 - 0.24 11.4 0.9 0.8 9.7 0.0 1.9 1 1 0 2 2 2 0 APOBEC2 IF4E PF01652.18 ORX97201.1 - 4.4e-55 185.8 1.5 5.3e-55 185.6 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Dus PF01207.17 ORX97202.1 - 5.5e-71 239.2 0.0 6.4e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 ORX97202.1 - 0.0006 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase ScsC_N PF18312.1 ORX97202.1 - 0.001 18.8 0.0 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain Oxidored_FMN PF00724.20 ORX97202.1 - 0.002 17.4 0.1 0.004 16.5 0.1 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 ORX97202.1 - 0.0037 16.8 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 ORX97202.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Acetyltransf_1 PF00583.25 ORX97203.1 - 1.1e-07 32.1 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX97203.1 - 0.0013 19.1 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX97203.1 - 0.0032 17.4 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORX97203.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MutL_C PF08676.11 ORX97206.1 - 2.8e-29 101.8 0.1 1.1e-28 99.9 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ORX97206.1 - 4.6e-22 77.9 0.0 1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORX97206.1 - 8.8e-12 45.0 0.1 3.9e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORX97206.1 - 5.9e-06 26.8 0.0 1.5e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2073 PF09846.9 ORX97206.1 - 0.14 12.0 0.2 19 5.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) SURF4 PF02077.15 ORX97207.1 - 5.5e-78 262.2 11.5 6.5e-78 262.0 11.5 1.0 1 0 0 1 1 1 1 SURF4 family DUF4231 PF14015.6 ORX97207.1 - 2.7 8.5 0.0 2.7 8.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) HR_lesion PF05514.11 ORX97207.1 - 4 7.6 12.4 5.9 7.1 2.4 2.7 2 2 1 3 3 3 0 HR-like lesion-inducing S_4TM PF18159.1 ORX97207.1 - 6.8 5.9 6.5 0.87 8.8 1.0 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Methyltr_RsmB-F PF01189.17 ORX97208.1 - 1.2e-29 103.4 0.0 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORX97208.1 - 0.0088 16.2 0.0 0.093 12.8 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 ORX97208.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin Cyclin PF08613.11 ORX97209.1 - 5.8e-13 49.5 0.0 7.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX97209.1 - 4e-08 33.0 0.0 5.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain STE PF02200.16 ORX97212.1 - 0.089 13.2 0.4 0.21 12.0 0.4 1.6 1 1 0 1 1 1 0 STE like transcription factor Spt20 PF12090.8 ORX97213.1 - 0.4 10.3 12.4 0.54 9.8 12.4 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 ORX97213.1 - 0.97 9.4 17.7 1.2 9.0 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit cNMPbd_u2 PF16643.5 ORX97213.1 - 3.7 8.0 10.2 0.37 11.3 4.3 2.1 1 1 2 3 3 3 0 Unstructured region on cNMP-binding protein Voldacs PF03517.13 ORX97215.1 - 8.3e-33 113.4 1.2 1.2e-32 112.9 1.2 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling GRAM PF02893.20 ORX97215.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 GRAM domain MMS22L_C PF14911.6 ORX97215.1 - 0.21 10.6 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Peptidase_A22B PF04258.13 ORX97216.1 - 0.11 12.0 10.8 0.18 11.3 10.8 1.3 1 0 0 1 1 1 0 Signal peptide peptidase Metallophos PF00149.28 ORX97217.1 - 2.4e-10 41.2 0.4 3.3e-10 40.8 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Inhibitor_I78 PF11720.8 ORX97218.1 - 6.7e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORX97218.1 - 0.026 15.2 0.1 0.051 14.2 0.1 1.5 1 1 1 2 2 2 0 Potato inhibitor I family Helo_like_N PF17111.5 ORX97219.1 - 0.027 13.8 1.2 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF4646 PF15496.6 ORX97220.1 - 0.0076 16.9 0.7 0.046 14.3 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 ORX97220.1 - 0.072 13.2 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family BRD4_CDT PF17105.5 ORX97220.1 - 0.49 10.0 3.9 0.94 9.1 3.9 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 ThrE PF06738.12 ORX97252.1 - 6.7e-43 146.8 16.2 2e-40 138.7 2.4 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORX97252.1 - 6.1e-07 29.6 22.9 0.00043 20.4 7.6 2.7 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE zf-C2H2 PF00096.26 ORX97253.1 - 1.2e-14 53.8 18.5 1.7e-06 28.1 0.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97253.1 - 1.7e-10 40.9 19.7 2e-07 31.1 0.6 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX97253.1 - 8.5e-09 35.5 17.4 9.4e-05 22.9 0.2 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX97253.1 - 6.3e-05 23.2 4.0 0.24 11.7 0.1 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon DUF4806 PF16064.5 ORX97253.1 - 6.8e-05 23.1 0.1 0.00016 21.9 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4806) FOXP-CC PF16159.5 ORX97253.1 - 9e-05 23.0 7.8 0.25 12.0 1.5 4.0 1 1 3 4 4 4 3 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORX97253.1 - 0.00041 20.6 5.3 0.22 11.7 0.8 3.1 1 1 3 4 4 4 3 Aberrant zinc-finger zf_ZIC PF18366.1 ORX97253.1 - 0.0035 17.4 2.2 1.1 9.4 0.0 3.7 3 1 0 3 3 3 1 Zic proteins zinc finger domain zf-TRAF PF02176.18 ORX97253.1 - 0.0056 17.4 8.2 0.0076 16.9 0.9 3.1 1 1 3 4 4 4 1 TRAF-type zinc finger zf-LYAR PF08790.11 ORX97253.1 - 0.044 13.7 1.6 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF494 PF04361.13 ORX97253.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) zf-C2H2_6 PF13912.6 ORX97253.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 ORX97253.1 - 0.81 9.7 7.2 1.1 9.3 0.4 3.1 2 1 0 2 2 2 0 Zap1 zinc finger 2 ATP_bind_3 PF01171.20 ORX97254.1 - 1.5e-45 155.2 0.0 3.7e-45 153.9 0.0 1.7 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.21 ORX97254.1 - 4.2e-06 26.7 0.0 9.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 ORX97254.1 - 0.00069 19.2 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 ORX97254.1 - 0.0036 16.5 0.2 0.043 12.9 0.0 2.5 3 0 0 3 3 3 1 NAD synthase NBD94 PF16830.5 ORX97254.1 - 0.0048 17.3 2.8 0.98 9.8 0.0 3.0 3 0 0 3 3 3 1 Nucleotide-Binding Domain 94 of RH TRPM_tetra PF16519.5 ORX97254.1 - 0.022 14.9 1.2 0.14 12.3 1.2 2.4 1 1 0 1 1 1 0 Tetramerisation domain of TRPM T3SSipB PF16535.5 ORX97254.1 - 0.069 13.6 0.7 0.14 12.7 0.7 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB RAG1 PF12940.7 ORX97254.1 - 0.075 11.1 0.0 0.12 10.4 0.0 1.2 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase PAPS_reduct PF01507.19 ORX97254.1 - 0.14 12.2 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family ApoLp-III PF07464.11 ORX97254.1 - 0.16 12.1 8.1 0.08 13.0 1.1 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) FliJ PF02050.16 ORX97254.1 - 0.22 11.8 3.0 0.14 12.4 0.7 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein Tropomyosin_1 PF12718.7 ORX97254.1 - 0.32 11.2 4.1 0.71 10.0 4.1 1.5 1 0 0 1 1 1 0 Tropomyosin like COG2 PF06148.11 ORX97254.1 - 0.34 11.0 2.8 1.1 9.4 0.4 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 ORX97254.1 - 0.79 10.2 7.9 4.1 7.9 1.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 ORX97254.1 - 1.5 8.8 6.7 11 6.0 0.3 2.8 3 0 0 3 3 2 0 Prefoldin subunit XhlA PF10779.9 ORX97254.1 - 2.9 8.2 7.5 2.6 8.3 0.7 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 ORX97254.1 - 5.2 7.6 7.7 1.7 9.2 0.9 2.8 2 1 1 3 3 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 ORX97254.1 - 8.5 6.6 7.4 3.4 7.8 0.5 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Sel1 PF08238.12 ORX97255.1 - 5.3e-35 119.1 15.9 8.7e-09 35.8 0.2 7.3 7 0 0 7 7 7 6 Sel1 repeat JUPITER PF17054.5 ORX97255.1 - 2.6 7.4 8.5 3.4 7.1 7.9 1.4 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter PQ-loop PF04193.14 ORX97256.1 - 3.4e-31 106.8 6.0 5.5e-16 58.1 0.8 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 ORX97256.1 - 0.26 11.4 5.8 1.5 9.0 0.8 2.9 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange NiFe_hyd_3_EhaA PF17367.2 ORX97256.1 - 1.7 8.8 10.0 0.33 11.1 5.3 2.2 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A Ada3 PF10198.9 ORX97257.1 - 3.8e-33 114.4 8.3 8e-33 113.4 8.3 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 MMR_HSR1_Xtn PF16897.5 ORX97257.1 - 0.083 12.9 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF3071 PF11268.8 ORX97257.1 - 0.097 12.7 1.0 0.17 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Sulfotransfer_3 PF13469.6 ORX97258.1 - 0.0026 18.2 0.1 0.0044 17.4 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family zf-CCCH PF00642.24 ORX97259.1 - 8.5e-14 51.1 21.9 3.4e-09 36.4 2.1 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX97259.1 - 1.9e-06 27.7 1.7 1.9e-06 27.7 1.7 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORX97259.1 - 5.7e-06 26.0 18.3 0.0011 18.7 0.7 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORX97259.1 - 0.0082 16.8 13.7 0.093 13.4 6.2 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 ORX97259.1 - 0.14 12.6 0.4 0.14 12.6 0.4 2.8 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger oligo_HPY PF08352.12 ORX97259.1 - 1.4 9.5 10.0 1 10.0 0.8 2.2 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region RasGEF PF00617.19 ORX97260.1 - 1.9e-49 168.2 0.0 2.4e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain DPBB_1 PF03330.18 ORX97261.1 - 2.9e-10 40.3 0.1 4.8e-10 39.6 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORX97261.1 - 6.8e-05 22.7 0.1 8.5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Barwin family Transket_pyr PF02779.24 ORX97262.1 - 1.9e-59 200.3 0.0 2.8e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORX97262.1 - 1.2e-50 171.2 0.0 2.2e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORX97262.1 - 6e-47 160.0 0.0 1.5e-46 158.8 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component Peptidase_M28 PF04389.17 ORX97263.1 - 1.4e-38 132.6 0.0 1.8e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 ORX97263.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Nicastrin EF-hand_13 PF17958.1 ORX97264.1 - 3.5e-24 84.4 0.1 1.5e-22 79.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ORX97264.1 - 2.2e-17 63.2 5.7 3.1e-14 53.2 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ORX97264.1 - 2.3e-05 24.0 1.7 0.003 17.3 0.0 4.1 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 ORX97264.1 - 0.00074 18.9 2.4 0.00083 18.8 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 ORX97264.1 - 0.00092 18.6 7.6 0.0033 16.9 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 ORX97264.1 - 0.0012 18.6 1.4 0.049 13.5 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORX97264.1 - 0.013 15.8 1.0 1.8 8.9 0.0 2.8 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF963 PF06131.11 ORX97265.1 - 1.8 8.0 8.5 0.17 11.3 2.5 2.6 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) PH PF00169.29 ORX97266.1 - 1.8e-11 44.5 0.5 4.5e-11 43.2 0.5 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 ORX97266.1 - 0.12 12.7 4.0 0.13 12.6 1.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Myosin_head PF00063.21 ORX97267.1 - 9.2e-252 837.1 0.1 1.6e-251 836.3 0.1 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORX97267.1 - 2.9e-21 75.7 0.4 2.9e-21 75.7 0.4 3.7 4 1 1 5 5 5 1 DIL domain IQ PF00612.27 ORX97267.1 - 1.2e-11 43.3 38.5 0.00011 21.7 0.1 7.0 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.6 ORX97267.1 - 0.0033 17.7 0.1 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX97267.1 - 0.017 15.5 0.2 0.086 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 ORX97267.1 - 0.038 14.5 1.4 2.3 8.7 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Leu_zip PF15294.6 ORX97267.1 - 0.13 11.7 12.1 0.38 10.2 12.1 1.7 1 0 0 1 1 1 0 Leucine zipper APG6_N PF17675.1 ORX97267.1 - 0.15 12.6 11.2 0.53 10.8 11.2 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 ORX97267.1 - 0.19 11.8 11.4 0.53 10.4 11.4 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 ORX97267.1 - 0.29 11.3 13.9 0.11 12.7 10.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CorA PF01544.18 ORX97267.1 - 0.66 9.2 5.4 1.4 8.1 5.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF724 PF05266.14 ORX97267.1 - 1.9 8.3 10.1 5.7 6.7 10.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 ORX97267.1 - 4.8 7.7 10.8 4.3 7.9 1.1 3.4 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 ORX97267.1 - 5.1 7.8 7.7 4.1 8.1 3.6 2.8 1 1 1 2 2 2 0 Initiation control protein YabA CorA PF01544.18 ORX97269.1 - 2.5e-52 178.0 2.7 2.9e-52 177.8 2.7 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.6 ORX97269.1 - 0.11 13.1 1.1 1.6 9.3 0.1 2.5 2 0 0 2 2 2 0 ACT domain ACOX PF01756.19 ORX97270.1 - 7.3e-53 178.8 0.0 1.3e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORX97270.1 - 1.6e-18 66.7 0.1 2.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORX97270.1 - 7.5e-14 52.4 0.0 2.8e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORX97270.1 - 1.3e-07 32.0 0.1 5.3e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TcdB_N PF12918.7 ORX97270.1 - 0.074 13.3 0.3 8.1 6.8 0.3 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain zf-H2C2_2 PF13465.6 ORX97271.1 - 2.6e-11 43.4 8.0 6.4e-10 39.0 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX97271.1 - 3.3e-08 33.6 11.4 2.5e-06 27.6 4.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97271.1 - 3.9e-08 33.5 9.9 2.9e-05 24.5 3.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX97271.1 - 5.1e-06 26.6 4.3 0.037 14.3 1.4 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX97271.1 - 0.00017 21.9 4.0 0.16 12.4 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORX97271.1 - 0.0085 15.8 2.0 0.0085 15.8 2.0 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-Di19 PF05605.12 ORX97271.1 - 0.011 16.0 2.8 0.012 15.8 2.8 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Sprouty PF05210.13 ORX97271.1 - 0.066 13.6 1.7 0.067 13.6 1.7 1.1 1 0 0 1 1 1 0 Sprouty protein (Spry) DUF2225 PF09986.9 ORX97271.1 - 0.12 12.1 2.9 0.72 9.5 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BolA PF01722.18 ORX97271.1 - 0.13 12.6 0.6 0.88 9.9 0.7 1.9 1 1 0 1 1 1 0 BolA-like protein zf-C2H2_2 PF12756.7 ORX97271.1 - 0.13 12.6 7.4 1.1 9.7 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_recom PF13408.6 ORX97271.1 - 0.13 12.8 3.6 0.18 12.4 3.6 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-LYAR PF08790.11 ORX97271.1 - 0.21 11.5 5.1 0.9 9.5 0.2 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.6 ORX97271.1 - 1.4 8.9 8.4 0.27 11.2 1.5 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX97271.1 - 1.6 8.5 14.0 0.18 11.6 8.6 2.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain RRM_1 PF00076.22 ORX97272.1 - 1.9e-30 104.5 0.0 1.7e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORX97272.1 - 8.7e-25 85.0 0.0 2.4e-05 23.8 0.0 6.0 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 ORX97272.1 - 4.7e-09 36.0 0.0 0.0043 16.9 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORX97272.1 - 0.0017 18.0 0.0 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.9 ORX97272.1 - 0.0081 15.7 0.0 0.086 12.3 0.0 2.2 2 0 0 2 2 2 1 RNA-recognition motif RRM_8 PF11835.8 ORX97272.1 - 0.054 13.7 0.0 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 RRM-like domain FlxA PF14282.6 ORX97272.1 - 0.056 13.4 10.9 0.14 12.2 10.9 1.6 1 0 0 1 1 1 0 FlxA-like protein TFIIF_alpha PF05793.12 ORX97273.1 - 6.6e-27 94.3 41.8 6.6e-24 84.4 41.8 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Trans_reg_C PF00486.28 ORX97273.1 - 0.23 11.6 2.2 5.4 7.2 0.4 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Presenilin PF01080.17 ORX97273.1 - 7.3 5.2 9.6 12 4.6 9.6 1.3 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 ORX97274.1 - 1.9e-11 43.7 16.8 1.4e-07 31.6 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97274.1 - 1e-08 35.3 13.7 2.8e-05 24.6 2.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX97274.1 - 1.4e-08 34.8 5.8 0.00035 20.8 0.7 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORX97274.1 - 1.5e-07 31.6 4.8 1.5e-07 31.6 4.8 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORX97274.1 - 9.5e-06 25.8 5.8 0.039 14.3 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORX97274.1 - 0.02 14.6 5.2 0.21 11.4 0.5 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-trcl PF13451.6 ORX97274.1 - 0.039 13.8 3.0 0.082 12.8 0.2 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-FCS PF06467.14 ORX97274.1 - 0.07 13.1 5.3 1 9.3 0.6 2.2 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn-ribbon_8 PF09723.10 ORX97274.1 - 0.2 11.8 6.7 0.18 11.9 3.4 2.3 1 1 1 2 2 2 0 Zinc ribbon domain DUF2256 PF10013.9 ORX97274.1 - 0.43 10.8 5.7 2.6 8.2 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.12 ORX97274.1 - 0.67 10.2 7.9 0.95 9.8 0.3 2.5 1 1 0 2 2 2 0 TFIIH C1-like domain zf-AN1 PF01428.16 ORX97274.1 - 6.5 7.0 16.7 22 5.3 1.6 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger DUF2757 PF10955.8 ORX97274.1 - 7.7 6.9 9.3 13 6.1 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) zf-H2C2_2 PF13465.6 ORX97275.1 - 2.6e-13 49.7 8.7 5.6e-11 42.4 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORX97275.1 - 3e-10 40.0 9.9 3.5e-07 30.3 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97275.1 - 2.7e-08 34.0 7.4 0.00011 22.7 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX97275.1 - 9.2e-05 22.6 1.7 0.038 14.3 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX97275.1 - 0.00058 20.2 3.2 0.16 12.4 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORX97275.1 - 0.0048 17.0 2.0 1.1 9.4 0.2 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_6 PF13912.6 ORX97275.1 - 0.021 14.8 6.3 0.71 9.9 0.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 ORX97275.1 - 0.024 14.2 0.8 0.89 9.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 ORX97275.1 - 0.087 12.7 4.9 0.74 9.8 0.4 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 ORX97275.1 - 0.13 12.5 4.4 0.52 10.6 0.2 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-H2C2_5 PF13909.6 ORX97275.1 - 0.61 9.9 13.4 1.7 8.5 4.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 ORX97275.1 - 2.2 8.5 8.8 5.8 7.2 2.2 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger SSP160 PF06933.11 ORX97277.1 - 0.078 11.2 3.0 0.1 10.8 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SRP-alpha_N PF04086.13 ORX97277.1 - 6.2 6.7 31.3 1.9 8.4 6.8 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Myb_DNA-bind_4 PF13837.6 ORX97278.1 - 4.8e-16 58.9 3.3 4.8e-16 58.9 3.3 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORX97278.1 - 7.8e-06 26.8 8.6 2.2e-05 25.3 3.7 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX97278.1 - 1.5e-05 25.2 1.2 1.5e-05 25.2 1.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 ORX97278.1 - 6.6e-05 23.1 4.2 0.00015 21.9 4.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX97278.1 - 0.00047 20.3 1.8 0.00089 19.4 1.8 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORX97278.1 - 0.0069 16.4 3.8 0.019 15.0 3.8 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4854 PF16146.5 ORX97278.1 - 0.034 14.5 0.2 0.13 12.6 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) KMP11 PF03037.16 ORX97278.1 - 0.034 14.9 2.0 0.14 12.9 2.0 2.0 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Stimulus_sens_1 PF13756.6 ORX97278.1 - 0.046 14.3 4.0 4.7 7.8 0.1 3.5 3 2 0 3 3 3 0 Stimulus-sensing domain TUSC2 PF15000.6 ORX97278.1 - 0.24 11.7 3.0 4.4 7.6 0.1 2.9 2 1 1 3 3 3 0 Tumour suppressor candidate 2 Cas9_PI PF16595.5 ORX97278.1 - 2.4 8.0 6.6 0.94 9.3 1.4 2.2 2 0 0 2 2 2 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 APH PF01636.23 ORX97306.1 - 0.0004 20.4 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family CHAP PF05257.16 ORX97307.1 - 7.1e-11 42.5 1.0 1.2e-10 41.8 1.0 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX97309.1 - 0.00061 20.3 1.1 0.0015 19.1 1.0 1.7 1 1 0 1 1 1 1 CHAP domain ArgJ PF01960.18 ORX97310.1 - 1.1e-147 491.7 2.9 1.2e-147 491.5 2.9 1.0 1 0 0 1 1 1 1 ArgJ family ATP-grasp PF02222.22 ORX97310.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RRM_1 PF00076.22 ORX97311.1 - 2.6e-13 49.6 0.0 3e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR PF03114.18 ORX97312.1 - 4.6e-39 134.5 1.4 5.6e-39 134.2 1.4 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 ORX97312.1 - 0.00036 20.2 0.1 0.012 15.2 0.2 2.6 2 1 1 3 3 3 1 Arfaptin-like domain BAR_3 PF16746.5 ORX97312.1 - 0.0035 17.1 0.1 0.0048 16.6 0.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF4455 PF14643.6 ORX97312.1 - 0.064 11.9 0.4 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Crr6 PF08847.11 ORX97313.1 - 0.16 11.6 0.1 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Chlororespiratory reduction 6 FAD_binding_7 PF03441.14 ORX97314.1 - 1.7e-84 282.4 0.5 2.4e-84 281.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORX97314.1 - 7.9e-47 159.3 0.1 1.4e-46 158.5 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase DIT1_PvcA PF05141.12 ORX97314.1 - 0.028 13.9 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein VPS13 PF16908.5 ORX97315.1 - 1.9e-81 273.4 5.9 4.6e-79 265.6 0.8 4.2 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 ORX97315.1 - 9.6e-81 271.1 2.2 8.9e-77 258.1 0.0 4.0 3 1 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 ORX97315.1 - 9.8e-79 264.1 13.4 9.4e-78 260.9 3.8 3.8 4 0 0 4 4 4 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 ORX97315.1 - 1.6e-68 230.0 6.3 3.5e-62 209.3 0.2 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 ORX97315.1 - 3.9e-41 139.8 0.4 1.8e-39 134.5 0.2 3.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORX97315.1 - 4.2e-12 46.2 0.3 3.9e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain AMP-binding PF00501.28 ORX97316.1 - 7.8e-107 357.5 0.0 1.1e-106 357.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme tRNA_lig_kinase PF08303.11 ORX97318.1 - 0.069 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain TPR_1 PF00515.28 ORX97319.1 - 2e-60 198.3 33.9 1.3e-08 34.3 0.0 10.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORX97319.1 - 3.3e-52 170.4 28.3 4.6e-07 29.5 0.0 9.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORX97319.1 - 1.1e-39 131.3 24.2 4.1e-07 29.7 0.0 10.2 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 ORX97319.1 - 5.4e-29 100.6 7.0 3.8e-06 27.4 0.0 6.4 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORX97319.1 - 5.6e-29 98.4 24.0 0.00059 20.0 0.1 10.5 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORX97319.1 - 1.8e-28 96.8 16.0 0.00068 20.3 0.0 9.2 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORX97319.1 - 1.2e-26 93.0 14.9 1.1e-05 25.8 0.2 6.7 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 ORX97319.1 - 2e-26 90.0 18.7 0.0027 17.6 0.2 9.9 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 ORX97319.1 - 2.5e-25 88.5 22.9 8.9e-05 22.7 3.1 7.5 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 ORX97319.1 - 3.5e-25 86.9 24.4 0.00029 21.3 0.0 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 ORX97319.1 - 7.8e-22 76.7 34.5 9.8e-07 28.4 0.7 9.7 6 3 4 10 10 10 5 TPR repeat TPR_9 PF13371.6 ORX97319.1 - 3.8e-17 62.2 11.0 0.0014 18.8 0.2 6.2 2 2 5 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX97319.1 - 1.4e-10 41.2 18.9 2e-08 34.3 3.8 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORX97319.1 - 3e-10 39.8 15.4 0.041 13.1 0.9 6.0 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_21 PF09976.9 ORX97319.1 - 6e-07 29.4 9.1 0.2 11.4 0.1 4.7 4 3 0 4 4 4 3 Tetratricopeptide repeat-like domain SNAP PF14938.6 ORX97319.1 - 7e-05 22.4 18.1 0.38 10.2 0.2 4.9 3 3 1 4 4 4 3 Soluble NSF attachment protein, SNAP Tcf25 PF04910.14 ORX97319.1 - 0.0079 15.3 0.2 0.19 10.8 0.0 2.7 3 1 0 3 3 3 1 Transcriptional repressor TCF25 BTAD PF03704.17 ORX97319.1 - 0.013 15.9 7.2 11 6.5 0.1 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain DUF627 PF04781.12 ORX97319.1 - 0.022 14.7 0.4 2.9 8.0 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ChAPs PF09295.10 ORX97319.1 - 0.029 13.4 1.6 12 4.7 0.1 3.0 2 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 ORX97319.1 - 0.031 14.6 8.7 0.59 10.5 0.1 4.8 5 2 1 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORX97319.1 - 0.089 12.8 32.9 0.86 9.7 1.2 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX97319.1 - 0.4 10.6 24.7 9.5 6.2 0.2 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORX97319.1 - 0.46 10.6 13.5 49 4.1 0.1 6.2 6 1 1 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.12 ORX97319.1 - 2.7 7.7 6.9 32 4.2 0.1 4.3 3 3 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 DUF410 PF04190.13 ORX97319.1 - 2.8 7.7 8.5 11 5.8 3.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF410) NUC153 PF08159.12 ORX97321.1 - 3.5e-10 39.5 0.9 8e-10 38.4 0.9 1.7 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 ORX97321.1 - 3.3e-06 27.3 0.0 6.6e-05 23.1 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORX97321.1 - 0.0059 17.4 0.1 50 5.0 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Ribosomal_L16 PF00252.18 ORX97322.1 - 3.3e-46 156.6 0.1 3.9e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e S10_plectin PF03501.15 ORX97323.1 - 3.4e-47 158.4 0.2 4.1e-47 158.2 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORX97323.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Kinase-like PF14531.6 ORX97323.1 - 0.053 12.8 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Replic_Relax PF13814.6 ORX97323.1 - 0.073 13.1 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation DUF4364 PF14277.6 ORX97323.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2250 PF10007.9 ORX97323.1 - 0.13 12.4 1.3 4.3 7.5 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RIO1 PF01163.22 ORX97324.1 - 3.4e-41 140.9 0.1 5.6e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 ORX97324.1 - 2.8e-28 98.0 0.1 6.9e-28 96.7 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 ORX97324.1 - 1e-09 38.7 0.1 4.5e-05 23.5 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORX97324.1 - 7.2e-06 25.5 0.0 5.3e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.12 ORX97324.1 - 0.064 12.6 11.6 0.092 12.1 11.6 1.1 1 0 0 1 1 1 0 NOA36 protein Kinase-like PF14531.6 ORX97324.1 - 0.069 12.5 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like BUD22 PF09073.10 ORX97324.1 - 1.6 8.0 18.5 2.5 7.3 18.5 1.2 1 0 0 1 1 1 0 BUD22 Trypan_PARP PF05887.11 ORX97324.1 - 4.9 7.1 15.2 7.4 6.6 15.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) adh_short PF00106.25 ORX97325.1 - 1.5e-28 99.6 1.7 5.3e-28 97.8 1.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX97325.1 - 1.8e-24 86.6 0.6 3.7e-24 85.6 0.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX97325.1 - 0.058 13.3 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 ORX97325.1 - 0.09 12.1 0.5 0.18 11.1 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_L3 PF00297.22 ORX97326.1 - 9.3e-189 627.0 10.2 1.1e-188 626.8 10.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PX PF00787.24 ORX97327.1 - 1.4e-18 66.9 0.0 3.8e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 PX domain HABP4_PAI-RBP1 PF04774.15 ORX97328.1 - 0.0087 16.9 0.0 0.0098 16.7 0.0 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family TatD_DNase PF01026.21 ORX97329.1 - 5.7e-41 140.6 0.0 7.7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF1899 PF08953.11 ORX97330.1 - 3e-30 103.9 0.0 6.3e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 ORX97330.1 - 8.6e-21 73.6 0.7 1.8e-20 72.5 0.7 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 ORX97330.1 - 3.5e-19 68.8 3.5 0.0012 19.6 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX97330.1 - 4.3e-07 30.1 0.2 0.0009 19.5 0.2 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SHE3 PF17078.5 ORX97330.1 - 0.00065 19.5 1.8 0.001 18.8 1.8 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 ORX97330.1 - 0.0045 17.3 1.6 0.01 16.2 1.6 1.5 1 0 0 1 1 1 1 Csm1 N-terminal domain PRKG1_interact PF15898.5 ORX97330.1 - 0.01 16.7 3.8 0.019 15.9 3.8 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 ORX97330.1 - 0.01 15.2 3.8 0.017 14.5 3.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MCM_lid PF17855.1 ORX97330.1 - 0.022 15.2 0.8 0.049 14.1 0.8 1.7 1 0 0 1 1 1 0 MCM AAA-lid domain DUF641 PF04859.12 ORX97330.1 - 0.026 14.8 2.8 0.044 14.1 2.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) PspA_IM30 PF04012.12 ORX97330.1 - 0.027 14.1 2.9 0.041 13.5 2.9 1.2 1 0 0 1 1 1 0 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 ORX97330.1 - 0.09 13.0 6.1 0.14 12.4 6.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 ORX97330.1 - 0.11 12.7 2.0 0.22 11.7 2.0 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 ORX97330.1 - 0.43 11.1 8.1 0.76 10.3 8.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB KELK PF15796.5 ORX97330.1 - 0.54 10.7 6.4 1.4 9.4 6.4 1.6 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_DNA_bd PF12329.8 ORX97330.1 - 0.65 10.0 4.4 1.1 9.3 4.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.22 ORX97331.1 - 1.2e-11 44.2 0.0 2.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX97331.1 - 0.0041 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 ORX97331.1 - 0.018 15.3 0.6 0.034 14.4 0.6 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding 3Beta_HSD PF01073.19 ORX97332.1 - 1e-67 228.1 0.1 1.2e-67 227.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX97332.1 - 1.3e-30 106.7 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORX97332.1 - 4.1e-17 62.6 0.0 2.2e-16 60.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORX97332.1 - 3.2e-16 59.3 0.1 3e-11 43.0 0.1 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORX97332.1 - 6.3e-16 58.8 0.0 1e-15 58.1 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORX97332.1 - 4.7e-10 39.0 0.1 7.4e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORX97332.1 - 4.7e-08 32.5 0.6 2.6e-07 30.1 0.4 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORX97332.1 - 0.0033 17.0 0.1 0.0056 16.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family DUF364 PF04016.12 ORX97332.1 - 0.0078 15.8 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Putative heavy-metal chelation TrkA_N PF02254.18 ORX97332.1 - 0.015 15.6 0.5 0.036 14.3 0.1 1.9 3 0 0 3 3 3 0 TrkA-N domain Abhydrolase_1 PF00561.20 ORX97333.1 - 7.3e-07 29.1 0.0 1.8e-06 27.8 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX97333.1 - 0.00019 22.1 0.0 0.00027 21.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ORX97333.1 - 0.0039 15.9 0.0 0.0054 15.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 ORX97333.1 - 0.0085 15.4 0.0 0.21 10.8 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 ORX97333.1 - 0.028 14.4 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 ORX97333.1 - 0.07 12.6 0.3 0.24 10.9 0.3 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 ORX97333.1 - 0.11 12.0 0.1 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 ORX97333.1 - 0.19 11.5 0.0 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family WD40 PF00400.32 ORX97334.1 - 0.0014 19.4 0.1 0.0014 19.4 0.1 4.5 4 2 1 5 5 5 1 WD domain, G-beta repeat CPSF_A PF03178.15 ORX97334.1 - 0.0064 15.9 0.3 0.025 13.9 0.1 1.8 1 1 0 2 2 2 1 CPSF A subunit region Proteasom_Rpn13 PF04683.13 ORX97334.1 - 0.16 12.5 0.0 2.4 8.8 0.0 2.3 1 1 1 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor IGPS PF00218.21 ORX97335.1 - 2.5e-93 311.9 1.1 2.8e-93 311.7 0.4 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 ORX97335.1 - 5.7e-55 186.1 0.8 2.7e-48 164.3 0.2 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 ORX97335.1 - 2.7e-49 167.5 0.1 4.7e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORX97335.1 - 3.4e-06 27.0 0.3 2.4e-05 24.2 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 ORX97335.1 - 0.00012 22.0 0.7 0.0045 16.8 0.2 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 ORX97335.1 - 0.0033 16.6 0.1 0.2 10.8 0.0 3.1 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 ORX97335.1 - 0.0061 15.6 1.0 0.045 12.8 0.1 2.2 1 1 1 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ORX97335.1 - 0.058 12.8 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein HMGL-like PF00682.19 ORX97335.1 - 0.087 12.4 0.2 13 5.2 0.0 2.9 2 1 1 3 3 3 0 HMGL-like DUF4992 PF16383.5 ORX97335.1 - 0.097 12.2 0.1 0.95 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function GCV_T PF01571.21 ORX97336.1 - 4e-86 288.6 0.0 4.8e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORX97336.1 - 5.4e-19 67.9 0.0 1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 ORX97336.1 - 0.0017 18.5 0.1 0.0069 16.5 0.0 1.9 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family MSC PF09402.10 ORX97337.1 - 1.3e-47 162.9 0.0 2.1e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain CCSMST1 PF15013.6 ORX97337.1 - 0.29 11.3 1.3 6.4 7.0 0.6 2.5 2 0 0 2 2 2 0 CCSMST1 family Glyco_hydro_16 PF00722.21 ORX97338.1 - 8.9e-22 77.4 0.1 1.6e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Iron_permease PF04120.12 ORX97339.1 - 4.6e-40 136.4 17.5 3.2e-16 59.3 0.5 4.1 4 0 0 4 4 4 4 Low affinity iron permease Rap_GAP PF02145.15 ORX97362.1 - 4.2e-62 209.0 0.0 9.5e-62 207.9 0.0 1.6 2 0 0 2 2 2 1 Rap/ran-GAP Myb_DNA-binding PF00249.31 ORX97365.1 - 3.1e-36 123.3 9.9 5.1e-10 39.4 0.0 4.2 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX97365.1 - 5.8e-35 119.3 9.6 1.4e-14 54.1 0.8 4.2 2 1 2 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORX97365.1 - 2.5e-11 43.3 2.7 0.004 17.0 0.1 3.3 2 1 1 3 3 3 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORX97365.1 - 2e-06 27.9 8.6 0.54 10.5 0.2 4.2 1 1 2 4 4 4 3 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 ORX97365.1 - 0.00013 21.9 3.1 0.15 12.1 0.0 4.1 2 1 2 4 4 4 2 SLIDE Rap1_C PF11626.8 ORX97365.1 - 0.044 13.9 0.1 0.92 9.6 0.1 2.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 ORX97365.1 - 0.06 13.5 0.4 0.43 10.8 0.0 2.7 3 1 0 3 3 3 0 Rap1 Myb domain Bac_globin PF01152.21 ORX97366.1 - 9.7e-10 38.6 0.1 1.3e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX97366.1 - 0.043 13.7 0.1 0.086 12.7 0.1 1.4 1 1 0 1 1 1 0 Protoglobin Prenyltransf PF01255.19 ORX97367.1 - 9.9e-80 267.3 0.0 1.2e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ion_trans_2 PF07885.16 ORX97368.1 - 1.4e-13 50.5 2.3 1.4e-13 50.5 2.3 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 ORX97368.1 - 6.1e-13 48.6 6.4 1.3e-12 47.5 6.4 1.5 1 1 0 1 1 1 1 Ion transport protein SID PF11778.8 ORX97368.1 - 0.078 13.1 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Septation initiation DUF2937 PF11157.8 ORX97368.1 - 1.8 8.3 3.6 2.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) E1_dh PF00676.20 ORX97369.1 - 2.3e-103 345.3 0.0 2.6e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component KRTAP7 PF15034.6 ORX97369.1 - 0.037 15.0 3.9 2 9.4 0.1 3.0 2 1 0 2 2 2 0 KRTAP type 7 family DXP_synthase_N PF13292.6 ORX97369.1 - 0.042 13.0 0.1 0.068 12.4 0.0 1.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF3112 PF11309.8 ORX97370.1 - 1.2 8.5 7.7 0.06 12.8 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF5058 PF16481.5 ORX97370.1 - 2 8.0 11.5 0.045 13.5 3.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5058) Sulfatase PF00884.23 ORX97372.1 - 6.4e-60 203.1 0.4 8.4e-60 202.8 0.4 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ORX97372.1 - 0.0017 18.0 1.7 0.015 14.9 0.2 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphoesterase PF04185.14 ORX97372.1 - 0.005 16.1 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoesterase family DUF229 PF02995.17 ORX97372.1 - 0.0066 15.1 0.0 0.13 10.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF229) RasGEF PF00617.19 ORX97373.1 - 5.2e-20 72.4 0.0 1.2e-19 71.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.19 ORX97374.1 - 1.2e-35 123.4 0.0 2.3e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Glyoxalase_4 PF13669.6 ORX97374.1 - 0.1 12.9 0.0 0.31 11.3 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.25 ORX97375.1 - 7.6e-68 228.7 0.0 1e-67 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97375.1 - 1.9e-38 132.2 0.0 2.6e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 ORX97375.1 - 1.2e-25 89.7 0.3 2.8e-25 88.5 0.3 1.6 1 0 0 1 1 1 1 PX domain Kdo PF06293.14 ORX97375.1 - 0.002 17.6 0.1 0.0067 15.8 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Polysacc_deac_1 PF01522.21 ORX97378.1 - 5.2e-32 110.4 0.1 1.6e-31 108.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Arrestin_N PF00339.29 ORX97380.1 - 5e-13 49.3 0.1 1.4e-12 47.9 0.1 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX97380.1 - 1.2e-09 38.7 1.0 7.7e-08 32.9 0.1 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX97380.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 Arrestin_N terminal like Rgp1 PF08737.10 ORX97380.1 - 0.033 13.4 0.1 0.063 12.4 0.1 1.4 1 1 0 1 1 1 0 Rgp1 AIM24 PF01987.17 ORX97381.1 - 4.6e-54 183.3 0.0 5.7e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PspB PF06667.12 ORX97382.1 - 0.021 14.8 0.2 0.05 13.7 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B FAD_binding_1 PF00667.20 ORX97406.1 - 4.8e-13 49.2 0.0 7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORX97406.1 - 5.1e-06 26.8 0.0 1.5e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flexi_CP PF00286.20 ORX97406.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 Viral coat protein DUF1775 PF07987.11 ORX97406.1 - 0.15 12.3 0.0 1.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) p450 PF00067.22 ORX97407.1 - 7.7e-87 292.0 0.0 9.4e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPRY PF00622.28 ORX97408.1 - 6.6e-17 61.7 0.1 7.7e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 SPRY domain DUF1883 PF08980.10 ORX97408.1 - 0.068 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) Peptidase_M28 PF04389.17 ORX97409.1 - 1.2e-39 136.0 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX97409.1 - 6.4e-16 58.2 0.2 1.6e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX97409.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORX97409.1 - 0.088 11.8 0.0 2.2 7.2 0.0 2.4 2 1 0 2 2 2 0 M42 glutamyl aminopeptidase ArfGap PF01412.18 ORX97410.1 - 4.5e-35 120.2 1.2 7.5e-35 119.5 0.5 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Aldose_epim PF01263.20 ORX97411.1 - 2.7e-69 233.8 0.1 3e-69 233.6 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.22 ORX97412.1 - 3.1e-06 26.9 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORX97412.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 MIF4G PF02854.19 ORX97413.1 - 9.8e-24 84.2 7.3 3.3e-23 82.4 7.3 2.0 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 ORX97413.1 - 9.3e-21 73.9 3.0 1.4e-20 73.4 0.0 2.8 3 0 0 3 3 3 1 MA3 domain DUF1674 PF07896.12 ORX97414.1 - 3.6e-20 72.2 4.0 5.6e-20 71.6 4.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) MFS_1 PF07690.16 ORX97415.1 - 6.5e-35 120.7 53.3 2.9e-29 102.1 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX97415.1 - 5e-05 22.3 26.7 0.00061 18.8 6.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORX97415.1 - 0.00012 21.1 1.0 0.00012 21.1 1.0 2.7 1 1 0 2 2 2 1 MFS_1 like family Antimicrobial24 PF16049.5 ORX97415.1 - 0.016 15.2 0.4 0.052 13.5 0.4 1.9 1 0 0 1 1 1 0 Frog antimicrobial peptide Tyrosinase PF00264.20 ORX97417.1 - 4.2e-37 128.6 9.2 2.6e-35 122.7 9.2 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase DNA_pol3_delta2 PF13177.6 ORX97418.1 - 1e-11 44.9 0.3 2.1e-11 43.8 0.3 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ORX97418.1 - 1.5e-07 31.9 0.2 3.7e-07 30.6 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORX97418.1 - 3.4e-06 27.1 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 ORX97418.1 - 0.00065 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 ORX97418.1 - 0.001 19.5 0.3 0.0038 17.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORX97418.1 - 0.0033 17.7 1.4 0.037 14.3 0.4 2.8 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORX97418.1 - 0.0045 17.5 0.0 0.0077 16.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter DNA_pol3_delta PF06144.13 ORX97418.1 - 0.0095 15.7 0.3 0.017 14.9 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 ORX97418.1 - 0.017 14.9 0.7 0.084 12.6 0.5 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 ORX97418.1 - 0.046 13.8 0.6 1.6 8.8 0.2 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 ORX97418.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORX97418.1 - 0.14 11.9 0.8 2.8 7.6 0.8 2.4 1 1 0 1 1 1 0 AAA domain Arrestin_C PF02752.22 ORX97419.1 - 3.7e-16 59.8 0.0 5.7e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX97419.1 - 4.4e-08 33.3 0.0 1.3e-06 28.6 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SAP30_Sin3_bdg PF13867.6 ORX97420.1 - 4.3e-16 59.0 1.0 6.5e-16 58.4 1.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Evr1_Alr PF04777.13 ORX97420.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Erv1 / Alr family cwf18 PF08315.12 ORX97421.1 - 0.13 12.9 0.7 1.6 9.4 0.8 2.2 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor Piwi PF02171.17 ORX97422.1 - 1.1e-106 356.5 0.1 1.7e-106 355.9 0.1 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORX97422.1 - 2.3e-28 99.6 0.0 5e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 ORX97422.1 - 4.3e-19 67.9 0.2 1e-18 66.7 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ORX97422.1 - 1.7e-17 63.5 0.0 3.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 ORX97422.1 - 2.9e-17 62.8 0.0 6.3e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 ORX97422.1 - 7e-11 42.2 0.0 2.1e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute BioT2 PF15368.6 ORX97423.1 - 0.19 11.7 0.4 0.45 10.5 0.3 1.6 1 1 0 1 1 1 0 Spermatogenesis family BioT2 rRNA_proc-arch PF13234.6 ORX97424.1 - 7.2e-83 278.6 0.0 1.3e-82 277.7 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 ORX97424.1 - 1e-54 184.6 0.6 1e-54 184.6 0.6 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 ORX97424.1 - 1.2e-17 64.2 0.0 4.3e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX97424.1 - 1.1e-07 32.2 0.1 1.6e-06 28.4 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX97424.1 - 0.00037 20.5 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORX97424.1 - 0.048 13.9 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX97424.1 - 0.13 12.7 0.1 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain zf-C3HC4_3 PF13920.6 ORX97425.1 - 2.2e-05 24.2 9.6 3.5e-05 23.6 9.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX97425.1 - 0.16 11.8 14.3 0.26 11.2 14.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX97425.1 - 0.98 9.3 12.8 1.9 8.4 12.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Form_Nir_trans PF01226.17 ORX97426.1 - 1.1e-68 231.2 24.0 1.2e-68 231.0 24.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter E1-E2_ATPase PF00122.20 ORX97427.1 - 2e-53 180.6 1.4 2e-53 180.6 1.4 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX97427.1 - 1.8e-47 161.4 11.9 1.8e-47 161.4 10.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORX97427.1 - 3.1e-23 83.2 1.5 2.3e-20 73.8 0.2 4.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX97427.1 - 2.2e-21 75.7 0.1 4.3e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX97427.1 - 5e-20 71.0 0.1 1.8e-19 69.2 0.1 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX97427.1 - 3.3e-07 30.3 1.5 6e-06 26.2 1.3 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX97427.1 - 1.7e-05 25.3 0.0 5e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC2_membrane_2 PF12679.7 ORX97427.1 - 9.8 5.4 10.7 0.14 11.4 1.1 2.6 2 1 1 3 3 3 0 ABC-2 family transporter protein HMG_box PF00505.19 ORX97429.1 - 8.6e-45 151.0 7.9 9.5e-22 77.2 0.1 3.9 4 0 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX97429.1 - 1.3e-31 108.9 8.3 5.5e-15 55.7 0.1 3.5 4 0 0 4 4 4 3 HMG-box domain CHDNT PF08073.12 ORX97429.1 - 1.4e-05 25.0 0.0 0.087 12.8 0.0 2.7 2 0 0 2 2 2 2 CHDNT (NUC034) domain HMG_box_5 PF14887.6 ORX97429.1 - 0.00055 19.8 0.3 0.0017 18.3 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box 5 BRK PF07533.16 ORX97429.1 - 0.0041 16.7 0.0 1.5 8.5 0.0 2.9 3 0 0 3 3 3 2 BRK domain Protamine_like PF06382.11 ORX97429.1 - 0.086 13.0 2.3 0.1 12.8 1.1 1.9 1 1 1 2 2 2 0 Protamine and protamine like SNF2_N PF00176.23 ORX97430.1 - 4.6e-42 144.0 0.0 7.4e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX97430.1 - 4.9e-20 71.9 0.9 1.3e-19 70.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 ORX97430.1 - 0.0088 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 ORX97430.1 - 0.014 15.4 0.2 0.048 13.7 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORX97430.1 - 0.048 12.9 0.0 0.048 12.9 0.0 2.1 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Phage_TAC_1 PF06222.11 ORX97430.1 - 0.11 12.2 0.0 6.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone p450 PF00067.22 ORX97461.1 - 5.3e-86 289.2 0.0 6.2e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 ORX97462.1 - 3.4e-18 65.4 0.2 4.2e-07 29.8 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein NUC173 PF08161.12 ORX97463.1 - 2.6e-75 252.6 1.4 2.6e-70 236.2 0.0 4.5 5 0 0 5 5 5 2 NUC173 domain MMS19_C PF12460.8 ORX97463.1 - 0.00029 20.1 1.3 0.00029 20.1 1.3 3.2 3 2 0 3 3 3 1 RNAPII transcription regulator C-terminal MFS_1 PF07690.16 ORX97464.1 - 2e-46 158.6 42.2 1.4e-44 152.5 22.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX97464.1 - 3.2e-11 42.7 11.6 3.2e-11 42.7 11.6 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ORX97464.1 - 4.8e-07 29.4 7.8 4.8e-07 29.4 7.8 2.6 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORX97464.1 - 9.9 4.3 18.8 5.6 5.1 0.8 3.3 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peripla_BP_2 PF01497.18 ORX97465.1 - 7.3e-05 22.4 0.0 0.0002 21.0 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein Lactamase_B PF00753.27 ORX97466.1 - 2.3e-11 44.1 1.7 5.5e-11 42.8 1.7 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORX97466.1 - 0.00013 21.5 0.3 0.00031 20.3 0.1 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain DUF4336 PF14234.6 ORX97466.1 - 0.00063 19.0 0.0 0.0028 16.9 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4336) Peptidase_S8 PF00082.22 ORX97467.1 - 5.4e-36 124.4 18.9 1.7e-35 122.7 18.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97467.1 - 1.8e-07 31.7 0.2 3.6e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97467.1 - 0.027 14.5 0.3 0.05 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX97468.1 - 3.6e-36 124.9 18.8 1.2e-35 123.3 18.8 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97468.1 - 1.8e-07 31.7 0.2 3.6e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97468.1 - 0.027 14.5 0.3 0.05 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein HMA PF00403.26 ORX97469.1 - 2.4e-16 59.9 1.0 2.6e-16 59.8 1.0 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain NapD PF03927.13 ORX97469.1 - 0.0031 17.5 0.1 0.0038 17.2 0.1 1.1 1 0 0 1 1 1 1 NapD protein Fer2_BFD PF04324.15 ORX97469.1 - 0.036 14.4 1.5 0.22 11.9 0.1 2.2 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_S8 PF00082.22 ORX97470.1 - 5.5e-36 124.4 18.9 1.7e-35 122.7 18.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97470.1 - 1.5e-07 32.0 0.3 3.1e-07 31.0 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97470.1 - 0.012 15.7 0.5 0.023 14.8 0.5 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX97471.1 - 5.4e-36 124.4 18.9 1.7e-35 122.7 18.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97471.1 - 1.8e-07 31.7 0.2 3.6e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97471.1 - 0.027 14.5 0.3 0.05 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein HMA PF00403.26 ORX97472.1 - 2.5e-16 59.9 1.0 2.7e-16 59.7 1.0 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain NapD PF03927.13 ORX97472.1 - 0.0032 17.5 0.1 0.004 17.2 0.1 1.1 1 0 0 1 1 1 1 NapD protein Fer2_BFD PF04324.15 ORX97472.1 - 0.038 14.3 1.5 0.24 11.8 0.1 2.2 2 1 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_S8 PF00082.22 ORX97473.1 - 3.9e-36 124.8 18.8 1.2e-35 123.2 18.8 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97473.1 - 1.7e-07 31.8 0.2 3.5e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97473.1 - 0.026 14.6 0.3 0.048 13.7 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX97474.1 - 3e-36 125.2 18.5 9.5e-36 123.6 18.5 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97474.1 - 2e-07 31.6 0.2 3.7e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97474.1 - 0.03 14.4 0.4 0.056 13.5 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX97475.1 - 5.7e-17 61.9 10.7 2.1e-16 60.0 10.7 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX97475.1 - 1.2e-07 32.3 0.2 2.1e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX97475.1 - 0.016 15.3 0.3 0.03 14.4 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Band_7 PF01145.25 ORX97476.1 - 8.4e-32 110.6 0.7 8.4e-32 110.6 0.7 2.0 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ORX97476.1 - 1e-27 96.0 2.0 2.4e-27 94.8 2.0 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 ORX97476.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family EDR1 PF14381.6 ORX97476.1 - 0.055 13.2 0.6 0.11 12.3 0.4 1.6 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 ELFV_dehydrog_N PF02812.18 ORX97477.1 - 1.2e-59 199.9 0.0 2e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX97477.1 - 1.8e-52 178.5 1.5 4.2e-51 174.0 0.2 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ORX97477.1 - 0.00034 20.0 0.2 0.00072 19.0 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRL PF13146.6 ORX97477.1 - 0.0016 18.7 0.1 0.28 11.5 0.1 2.9 3 0 0 3 3 3 1 TRL-like protein family AdoHcyase_NAD PF00670.21 ORX97477.1 - 0.0037 17.4 0.2 0.0085 16.2 0.2 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORX97477.1 - 0.0046 17.4 0.1 0.012 16.1 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Bac_GDH PF05088.12 ORX97477.1 - 0.061 10.8 0.2 0.16 9.4 0.1 1.7 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORX97478.1 - 1e-59 200.1 0.0 1.7e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX97478.1 - 7.3e-54 183.1 0.6 1.2e-53 182.4 0.6 1.4 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ORX97478.1 - 0.00036 19.9 0.2 0.00064 19.1 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORX97478.1 - 0.0031 17.9 0.1 0.007 16.8 0.1 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 ORX97478.1 - 0.0032 17.5 0.2 0.0075 16.3 0.2 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_GDH PF05088.12 ORX97478.1 - 0.055 11.0 0.1 0.17 9.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 ORX97479.1 - 1.5e-54 185.3 2.3 2e-53 181.6 0.5 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORX97479.1 - 6.2e-38 129.6 0.4 2.8e-35 121.0 0.0 2.4 1 1 1 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 ORX97479.1 - 0.00038 19.9 0.2 0.00075 18.9 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRL PF13146.6 ORX97479.1 - 0.0013 18.9 0.0 0.13 12.5 0.1 2.5 2 0 0 2 2 2 1 TRL-like protein family AdoHcyase_NAD PF00670.21 ORX97479.1 - 0.0034 17.5 0.1 0.0086 16.2 0.1 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORX97479.1 - 0.0046 17.4 0.1 0.012 16.0 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Bac_GDH PF05088.12 ORX97479.1 - 0.06 10.8 0.3 0.17 9.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORX97480.1 - 1.4e-59 199.6 0.0 2.4e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX97480.1 - 3.1e-58 197.4 5.6 1.7e-52 178.6 2.7 3.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ORX97480.1 - 1.1e-06 28.2 0.5 0.00077 18.9 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRL PF13146.6 ORX97480.1 - 2.4e-05 24.5 0.7 0.29 11.5 0.1 3.4 3 0 0 3 3 3 1 TRL-like protein family AdoHcyase_NAD PF00670.21 ORX97480.1 - 2.9e-05 24.2 0.4 0.007 16.4 0.2 2.6 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORX97480.1 - 0.00017 22.0 0.0 0.014 15.9 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Gp_dh_N PF00044.24 ORX97480.1 - 0.064 13.6 0.7 20 5.6 0.0 2.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Bac_GDH PF05088.12 ORX97480.1 - 0.076 10.5 0.2 0.19 9.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase ThiF PF00899.21 ORX97480.1 - 0.082 12.2 0.1 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 ThiF family DUF4035 PF13227.6 ORX97480.1 - 0.095 12.4 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) ELFV_dehydrog_N PF02812.18 ORX97481.1 - 1.1e-59 200.0 0.0 1.9e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ORX97481.1 - 1e-54 185.8 2.4 1.5e-53 182.0 0.4 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ORX97481.1 - 0.00034 20.0 0.2 0.00068 19.0 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRL PF13146.6 ORX97481.1 - 0.0025 18.0 0.0 0.27 11.6 0.1 2.4 2 0 0 2 2 2 1 TRL-like protein family AdoHcyase_NAD PF00670.21 ORX97481.1 - 0.0033 17.5 0.2 0.008 16.3 0.2 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ORX97481.1 - 0.0047 17.4 0.1 0.011 16.2 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Bac_GDH PF05088.12 ORX97481.1 - 0.053 11.0 0.1 0.15 9.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase Peptidase_M90 PF06167.12 ORX97482.1 - 2.9e-07 30.4 0.2 1.9e-06 27.7 0.2 2.0 1 1 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 Ribosomal_L14e PF01929.17 ORX97485.1 - 9.8e-32 109.3 3.4 1.4e-31 108.8 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORX97485.1 - 0.00068 19.5 0.5 0.0013 18.6 0.5 1.5 1 0 0 1 1 1 1 KOW motif DEAD PF00270.29 ORX97486.1 - 1.7e-42 145.1 0.0 3e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX97486.1 - 5.8e-26 91.0 0.0 1e-23 83.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX97486.1 - 9.2e-10 38.8 0.0 4.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORX97486.1 - 0.0016 17.7 0.3 0.0028 16.9 0.3 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 ORX97486.1 - 0.17 12.2 0.3 12 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cyclin PF08613.11 ORX97487.1 - 7.7e-36 123.9 0.9 1.7e-35 122.8 0.8 1.5 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX97487.1 - 2.4e-08 33.8 0.9 3.8e-08 33.1 0.8 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain AMP-binding PF00501.28 ORX97489.1 - 1.4e-46 158.9 0.0 2.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORX97489.1 - 8.9e-10 38.3 0.3 1.9e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ORX97489.1 - 0.19 12.8 0.2 0.83 10.7 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain EcoEI_R_C PF08463.10 ORX97490.1 - 0.015 15.4 1.6 0.47 10.6 0.1 2.7 2 0 0 2 2 2 0 EcoEI R protein C-terminal Goodbye PF17109.5 ORX97490.1 - 0.37 11.2 2.2 2 8.9 1.7 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Sugar_tr PF00083.24 ORX97491.1 - 4.4e-59 200.5 22.8 5.4e-59 200.2 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX97491.1 - 3e-28 98.8 26.6 7.8e-28 97.4 24.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX97491.1 - 4e-07 29.7 2.5 8.3e-07 28.6 2.5 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORX97491.1 - 0.00018 20.2 10.4 0.00018 20.2 10.4 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORX97491.1 - 0.0018 17.9 1.2 0.02 14.4 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORX97491.1 - 0.13 10.5 10.7 0.046 12.0 2.0 2.9 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family zf-RING_2 PF13639.6 ORX97519.1 - 1.1e-07 32.0 7.9 1.1e-07 32.0 7.9 2.0 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 ORX97519.1 - 1.9e-05 24.2 0.2 4.2e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 ORX97519.1 - 0.00014 21.7 5.0 0.00014 21.7 5.0 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 ORX97519.1 - 0.02 14.9 4.4 0.02 14.9 4.4 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX97519.1 - 0.027 14.5 2.6 0.027 14.5 2.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORX97519.1 - 0.033 14.4 8.3 0.082 13.1 5.6 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 ORX97519.1 - 0.036 13.9 7.3 0.097 12.5 7.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 ORX97519.1 - 0.038 13.8 2.0 0.038 13.8 2.0 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORX97519.1 - 0.059 13.3 10.8 0.12 12.3 10.8 1.5 1 0 0 1 1 1 0 PHD-finger baeRF_family12 PF18856.1 ORX97519.1 - 0.087 13.4 3.7 0.16 12.6 3.7 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 zf-C3HC4_3 PF13920.6 ORX97519.1 - 0.089 12.7 4.1 0.25 11.2 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX97519.1 - 0.53 10.1 3.7 1.6 8.5 3.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger OrfB_Zn_ribbon PF07282.11 ORX97519.1 - 0.69 9.9 8.3 22 5.1 0.0 3.5 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-RING_5 PF14634.6 ORX97519.1 - 1.8 8.6 10.8 0.23 11.5 6.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 ORX97519.1 - 4.3 7.5 11.5 12 6.1 11.5 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 ORX97519.1 - 5 7.1 7.4 17 5.4 7.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DJ-1_PfpI PF01965.24 ORX97520.1 - 6.3e-42 143.2 0.0 7.3e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX97520.1 - 5.8e-06 26.1 0.0 0.00022 21.0 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 ORX97520.1 - 0.0042 16.7 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 ORX97520.1 - 0.012 15.4 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Catalase_C PF18011.1 ORX97520.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases Peptidase_C26 PF07722.13 ORX97520.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 1 0 1 1 1 0 Peptidase C26 DUF724 PF05266.14 ORX97521.1 - 6.1e-05 22.9 10.6 0.0001 22.2 10.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) THOC7 PF05615.13 ORX97521.1 - 0.018 15.3 5.6 0.018 15.3 5.6 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 Tho2 PF11262.8 ORX97521.1 - 0.028 13.6 7.3 0.043 13.0 7.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NRBF2 PF08961.10 ORX97521.1 - 0.033 13.8 6.6 0.061 12.9 6.6 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ATG16 PF08614.11 ORX97521.1 - 0.14 12.4 20.3 0.24 11.6 19.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) End3 PF12761.7 ORX97521.1 - 0.23 11.6 16.7 2.1 8.5 11.0 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.19 ORX97521.1 - 0.27 9.1 8.9 0.35 8.7 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 ORX97521.1 - 0.54 9.3 12.8 0.91 8.5 12.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 ORX97521.1 - 0.55 9.4 12.5 0.82 8.9 12.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein EspB_PE PF18625.1 ORX97521.1 - 0.6 10.6 4.5 2.3 8.8 0.1 2.9 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain DUF4337 PF14235.6 ORX97521.1 - 0.72 10.0 7.9 1.4 9.1 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) YabA PF06156.13 ORX97521.1 - 0.89 10.2 14.6 0.82 10.3 11.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 ORX97521.1 - 1 8.9 8.9 1.4 8.4 8.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 ORX97521.1 - 1.2 7.9 8.7 1.7 7.5 8.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HIP1_clath_bdg PF16515.5 ORX97521.1 - 4.1 8.1 23.2 1.3 9.6 8.7 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GPR_Gpa2_C PF11970.8 ORX97522.1 - 0.84 9.8 5.3 0.41 10.8 0.2 3.0 4 0 0 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 C-term MatE PF01554.18 ORX97523.1 - 2.3e-45 154.1 31.7 4.3e-26 91.5 7.8 2.8 3 0 0 3 3 3 2 MatE RRM_1 PF00076.22 ORX97524.1 - 2.8e-05 23.8 0.2 0.00012 21.8 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.17 ORX97525.1 - 4.7e-35 121.1 0.0 9.3e-35 120.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORX97525.1 - 2.6e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CcmD PF04995.14 ORX97526.1 - 0.11 12.6 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1180 PF06679.12 ORX97528.1 - 0.099 13.1 7.0 0.12 12.8 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Phasin PF05597.11 ORX97528.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5521 PF17659.1 ORX97528.1 - 0.44 8.3 6.3 0.5 8.2 6.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Miga PF10265.9 ORX97528.1 - 0.54 9.2 4.5 0.58 9.1 4.5 1.0 1 0 0 1 1 1 0 Mitoguardin Calpain_inhib PF00748.19 ORX97528.1 - 1.4 9.4 9.6 1.7 9.2 9.6 1.1 1 0 0 1 1 1 0 Calpain inhibitor BES1_N PF05687.13 ORX97528.1 - 1.4 9.3 11.8 1.7 9.0 11.8 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Tyrosinase PF00264.20 ORX97529.1 - 0.14 12.4 1.0 0.17 12.2 1.0 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase SID-1_RNA_chan PF13965.6 ORX97529.1 - 0.45 8.9 1.4 0.56 8.6 1.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 ORX97529.1 - 1.1 7.9 6.6 1.2 7.8 6.6 1.2 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 ORX97529.1 - 1.5 9.3 8.4 1.8 9.1 8.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 ORX97529.1 - 1.9 7.1 12.4 2.3 6.8 12.4 1.1 1 0 0 1 1 1 0 Hamartin protein Miga PF10265.9 ORX97529.1 - 2.2 7.2 9.6 2.1 7.2 9.6 1.0 1 0 0 1 1 1 0 Mitoguardin SPX PF03105.19 ORX97529.1 - 2.4 8.0 12.4 2.8 7.8 12.4 1.0 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 ORX97529.1 - 3.3 4.7 10.4 3.6 4.6 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 ORX97529.1 - 6.7 4.7 7.8 7.2 4.6 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 ORX97529.1 - 8.3 4.8 12.8 9.1 4.7 12.8 1.1 1 0 0 1 1 1 0 Macoilin family Polysacc_deac_1 PF01522.21 ORX97530.1 - 1.5e-34 118.6 0.0 2.1e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX97530.1 - 0.0067 15.7 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX97530.1 - 0.098 12.3 0.5 0.59 9.7 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) G_glu_transpept PF01019.21 ORX97531.1 - 5.6e-147 490.6 0.0 6.4e-147 490.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase zf-C2H2 PF00096.26 ORX97532.1 - 1.4e-14 53.6 10.9 8.5e-07 29.1 3.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97532.1 - 1.6e-09 37.8 9.6 0.00017 22.2 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX97532.1 - 1.9e-07 31.2 16.7 8.4e-07 29.2 3.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain FOXP-CC PF16159.5 ORX97532.1 - 1.7e-05 25.3 2.5 0.12 13.0 0.2 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORX97532.1 - 9.4e-05 22.7 1.8 0.062 13.7 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX97532.1 - 0.00013 22.2 4.3 0.073 13.4 0.5 2.7 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORX97532.1 - 0.0008 19.6 4.4 0.0036 17.5 4.4 1.7 1 1 0 1 1 1 1 Aberrant zinc-finger zf-BED PF02892.15 ORX97532.1 - 0.0033 17.4 5.4 0.048 13.7 0.5 2.5 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_2 PF12756.7 ORX97532.1 - 0.015 15.6 4.3 0.05 14.0 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 ORX97532.1 - 0.02 15.2 2.0 0.097 13.0 1.8 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon RPAP2_Rtr1 PF04181.13 ORX97532.1 - 0.053 13.9 1.4 0.065 13.6 0.2 1.7 1 1 1 2 2 2 0 Rtr1/RPAP2 family zf-C2H2_6 PF13912.6 ORX97532.1 - 0.059 13.4 0.4 0.059 13.4 0.4 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX97532.1 - 7.8 6.3 22.0 2.5 7.9 2.5 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain ATP-synt_E PF05680.12 ORX97533.1 - 4.2e-25 87.9 0.1 4.7e-25 87.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.12 ORX97533.1 - 0.0018 18.5 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) Mnd1 PF03962.15 ORX97534.1 - 2e-30 104.8 0.3 2e-30 104.8 0.3 1.8 2 0 0 2 2 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 ORX97534.1 - 3.9e-22 78.1 1.3 3.9e-22 78.1 1.3 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Cep57_MT_bd PF06657.13 ORX97534.1 - 0.021 15.3 2.9 0.021 15.3 2.9 2.0 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Takusan PF04822.13 ORX97534.1 - 0.024 14.5 1.4 0.061 13.2 1.4 1.7 1 0 0 1 1 1 0 Takusan DHC_N2 PF08393.13 ORX97534.1 - 0.029 13.5 4.8 0.022 13.9 1.8 2.0 1 1 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Penicillinase_R PF03965.16 ORX97534.1 - 0.037 14.4 1.4 0.47 10.8 0.1 2.3 1 1 1 2 2 2 0 Penicillinase repressor DivIC PF04977.15 ORX97534.1 - 0.039 13.7 2.0 0.039 13.7 2.0 2.5 2 1 1 3 3 3 0 Septum formation initiator FUR PF01475.19 ORX97534.1 - 0.053 13.7 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Ferric uptake regulator family DUF4195 PF13836.6 ORX97534.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Prefoldin PF02996.17 ORX97534.1 - 0.088 12.7 0.0 0.088 12.7 0.0 2.4 3 0 0 3 3 3 0 Prefoldin subunit TrmB PF01978.19 ORX97534.1 - 0.12 12.3 0.2 0.62 10.0 0.0 2.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB FapA PF03961.13 ORX97534.1 - 0.19 10.3 7.0 0.05 12.2 3.5 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 ORX97534.1 - 0.44 11.1 14.4 0.036 14.6 9.2 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region bZIP_2 PF07716.15 ORX97534.1 - 0.67 10.1 5.0 1.3 9.2 0.9 3.0 3 0 0 3 3 3 0 Basic region leucine zipper CaM_bdg_C0 PF10562.9 ORX97534.1 - 0.85 9.7 4.5 1.6 8.9 0.6 2.6 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit GAS PF13851.6 ORX97534.1 - 2.3 7.5 13.4 0.66 9.3 7.7 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 ORX97534.1 - 6.7 7.1 10.2 3.1 8.2 5.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GGACT PF06094.12 ORX97535.1 - 2.5e-15 57.2 0.0 3.4e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_M24_C PF16188.5 ORX97535.1 - 0.11 12.6 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 zf-C2H2 PF00096.26 ORX97537.1 - 2.5e-16 59.1 8.9 3.5e-08 33.4 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97537.1 - 1.7e-10 40.8 7.8 9.8e-05 22.9 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX97537.1 - 1.5e-09 37.8 15.7 6.8e-09 35.8 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX97537.1 - 1e-05 25.7 1.9 0.053 13.8 0.6 2.5 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX97537.1 - 2.4e-05 24.9 0.8 0.021 15.5 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORX97537.1 - 0.00032 21.0 0.8 0.83 10.1 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 ORX97537.1 - 0.00032 20.9 1.8 0.0004 20.6 1.8 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-LYAR PF08790.11 ORX97537.1 - 0.0017 18.2 1.2 0.82 9.6 0.2 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-BED PF02892.15 ORX97537.1 - 0.0022 18.0 3.4 0.041 13.9 1.1 2.1 2 0 0 2 2 2 1 BED zinc finger FANCL_C PF11793.8 ORX97537.1 - 0.052 13.7 1.0 0.057 13.6 1.0 1.1 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C2H2_6 PF13912.6 ORX97537.1 - 0.07 13.1 0.1 0.07 13.1 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORX97537.1 - 0.97 9.3 18.8 1 9.1 2.9 3.2 3 1 0 3 3 3 0 C2H2-type zinc-finger domain SNF2_N PF00176.23 ORX97539.1 - 1.8e-50 171.6 0.0 3.4e-40 137.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX97539.1 - 5.6e-15 55.7 0.0 1.5e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORX97539.1 - 2.9e-06 27.0 2.7 2.9e-06 27.0 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX97539.1 - 9e-06 25.6 0.7 9e-06 25.6 0.7 2.9 2 2 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX97539.1 - 1.3e-05 25.0 4.4 1.3e-05 25.0 4.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX97539.1 - 2.9e-05 23.9 5.3 2.9e-05 23.9 5.3 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX97539.1 - 6.6e-05 22.7 3.5 6.6e-05 22.7 3.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORX97539.1 - 8.4e-05 22.5 3.4 8.4e-05 22.5 3.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain ResIII PF04851.15 ORX97539.1 - 0.00017 21.6 1.0 0.00048 20.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 ORX97539.1 - 0.0002 21.6 4.1 0.0002 21.6 4.1 2.5 2 0 0 2 2 1 1 Ring finger domain zf-Nse PF11789.8 ORX97539.1 - 0.045 13.6 1.2 0.1 12.4 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit rRNA_processing PF08524.11 ORX97539.1 - 0.8 9.7 11.5 2.5 8.1 11.5 1.8 1 0 0 1 1 1 0 rRNA processing CTP_transf_like PF01467.26 ORX97571.1 - 5.7e-28 97.9 0.0 8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like zinc_ribbon_6 PF14599.6 ORX97572.1 - 3.4e-25 87.8 3.3 3.4e-25 87.8 3.3 4.4 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 ORX97572.1 - 1.7e-19 70.0 19.6 1.7e-19 70.0 19.6 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 ORX97572.1 - 2e-08 34.4 9.9 2e-08 34.4 9.9 5.0 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORX97572.1 - 7.4e-05 22.5 8.3 7.4e-05 22.5 8.3 5.6 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX97572.1 - 8.4e-05 22.3 12.0 8.4e-05 22.3 12.0 5.1 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORX97572.1 - 0.032 14.0 6.7 0.032 14.0 6.7 4.2 4 0 0 4 4 4 0 RING-like zinc finger Nucleoporin_C PF03177.14 ORX97573.1 - 2e-80 271.3 10.9 8e-70 236.2 6.4 2.2 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 ORX97573.1 - 1.1e-18 67.2 0.6 1.7e-18 66.6 0.6 1.2 1 0 0 1 1 1 1 Nup133 N terminal like PMT PF02366.18 ORX97574.1 - 1.8e-82 276.6 16.1 1.8e-82 276.6 16.1 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX97574.1 - 3.7e-60 202.9 16.9 3.7e-60 202.9 16.9 3.0 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX97574.1 - 1.9e-32 112.6 1.5 2.9e-32 112.0 1.5 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 ORX97574.1 - 1.4e-07 31.9 13.7 1.4e-07 31.9 13.7 2.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GATase_2 PF00310.21 ORX97575.1 - 6.2e-184 611.6 0.0 8.5e-184 611.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORX97575.1 - 4.3e-158 526.3 0.0 5.2e-157 522.7 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORX97575.1 - 1.2e-115 385.8 0.0 3.7e-114 380.9 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 ORX97575.1 - 1.7e-86 288.7 3.6 2.9e-86 287.9 3.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ORX97575.1 - 3.9e-25 88.7 0.0 1.8e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ORX97575.1 - 7.4e-24 83.7 0.1 1.7e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 ORX97575.1 - 1.7e-09 38.1 0.1 9.6e-05 22.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX97575.1 - 8.4e-09 35.5 0.0 6.8e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORX97575.1 - 5.2e-06 25.9 0.0 0.014 14.7 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORX97575.1 - 1.5e-05 23.9 0.2 1.5e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 ORX97575.1 - 4.8e-05 22.8 0.0 8.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORX97575.1 - 6.2e-05 22.5 0.0 0.00018 21.0 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX97575.1 - 0.00016 21.0 0.2 0.033 13.5 0.0 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORX97575.1 - 0.00026 20.2 2.6 0.00041 19.6 0.0 2.4 3 0 0 3 3 2 1 FAD binding domain FAD_binding_3 PF01494.19 ORX97575.1 - 0.00038 19.8 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORX97575.1 - 0.00063 20.1 0.3 0.39 11.2 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 ORX97575.1 - 0.0041 16.3 2.5 0.07 12.2 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 ORX97575.1 - 0.0042 16.7 4.4 0.0044 16.7 0.1 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ORX97575.1 - 0.01 15.2 0.0 0.033 13.5 0.0 1.8 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.18 ORX97575.1 - 0.02 13.9 1.0 0.19 10.7 1.8 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Thi4 PF01946.17 ORX97575.1 - 0.036 13.3 1.9 0.048 12.9 0.0 2.1 3 0 0 3 3 3 0 Thi4 family GATase_6 PF13522.6 ORX97575.1 - 0.037 14.2 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase domain NAD_Gly3P_dh_N PF01210.23 ORX97575.1 - 0.037 14.0 0.0 0.14 12.2 0.0 2.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 ORX97575.1 - 0.071 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMO-like PF00743.19 ORX97575.1 - 0.075 11.4 0.0 1.4 7.3 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 ORX97575.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 ORX97575.1 - 0.11 12.1 0.2 0.37 10.4 0.2 1.9 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 ORX97575.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 ORX97575.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.6 ORX97575.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Rossmann-like PF10727.9 ORX97575.1 - 0.17 11.7 0.9 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain Lycopene_cycl PF05834.12 ORX97575.1 - 0.18 10.9 1.0 0.39 9.7 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein 6PGD PF00393.19 ORX97576.1 - 2.3e-127 424.3 0.0 3.6e-127 423.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORX97576.1 - 2e-52 177.5 0.0 2.9e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORX97576.1 - 0.0048 17.1 0.0 0.08 13.2 0.0 2.4 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORX97576.1 - 0.1 13.2 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DNA_pol3_beta PF00712.19 ORX97576.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain CoatB PF10389.9 ORX97576.1 - 0.23 11.3 3.3 0.4 10.6 0.5 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B Ribosomal_L38e PF01781.18 ORX97577.1 - 1.3e-35 121.3 1.7 1.4e-35 121.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORX97577.1 - 0.066 13.4 0.0 0.076 13.2 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORX97577.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 AAA PF00004.29 ORX97579.1 - 3.6e-37 127.8 0.0 9e-37 126.5 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORX97579.1 - 1.4e-09 37.8 0.1 1.1e-07 31.7 0.0 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 ORX97579.1 - 2.9e-09 36.6 0.0 1.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORX97579.1 - 5.2e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORX97579.1 - 6.7e-05 22.9 0.1 0.0006 19.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX97579.1 - 0.00019 21.9 1.6 0.072 13.5 0.1 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORX97579.1 - 0.00035 20.9 1.0 0.097 12.9 0.2 2.7 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 ORX97579.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORX97579.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 ORX97579.1 - 0.02 14.3 0.2 0.07 12.5 0.2 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORX97579.1 - 0.048 13.4 0.1 5.1 6.8 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_21 PF13304.6 ORX97579.1 - 0.058 13.2 0.1 0.99 9.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 ORX97579.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 ORX97579.1 - 0.13 11.6 0.1 17 4.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_14 PF13173.6 ORX97579.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORX97579.1 - 0.19 12.1 0.1 0.43 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORX97579.1 - 0.22 11.2 0.7 1.2 8.8 0.2 2.3 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 ORX97579.1 - 0.24 10.7 0.6 3.6 6.9 0.2 2.1 1 1 1 2 2 2 0 KaiC CBFD_NFYB_HMF PF00808.23 ORX97580.1 - 4.5e-21 74.9 1.3 6.9e-21 74.3 1.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX97580.1 - 6.2e-19 68.7 0.6 7.8e-19 68.3 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 ORX97580.1 - 0.0034 17.7 0.3 0.0054 17.0 0.3 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Pex19 PF04614.12 ORX97581.1 - 1.3e-60 205.2 17.8 2e-60 204.6 17.8 1.3 1 0 0 1 1 1 1 Pex19 protein family Dynamin_M PF01031.20 ORX97581.1 - 0.00081 18.7 1.4 0.00081 18.7 1.4 1.5 2 0 0 2 2 2 1 Dynamin central region MotY_N PF18393.1 ORX97581.1 - 0.15 12.2 2.4 0.12 12.4 0.8 1.7 2 0 0 2 2 2 0 MotY N-terminal domain COG2 PF06148.11 ORX97581.1 - 0.17 12.0 3.6 0.29 11.2 2.5 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fzo_mitofusin PF04799.13 ORX97581.1 - 0.18 11.3 1.2 0.41 10.2 1.2 1.5 1 0 0 1 1 1 0 fzo-like conserved region ORF_12_N PF18042.1 ORX97581.1 - 0.38 11.2 2.6 10 6.6 0.2 2.6 2 0 0 2 2 2 0 ORF 12 gene product N-terminal DUF445 PF04286.12 ORX97581.1 - 0.54 10.0 3.3 2.1 8.1 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Interferon PF00143.19 ORX97581.1 - 1.1 9.5 5.2 0.44 10.7 2.2 1.9 2 1 0 2 2 2 0 Interferon alpha/beta domain FlaG PF03646.15 ORX97581.1 - 8.2 6.7 12.8 7.8 6.7 2.5 3.0 2 1 0 2 2 2 0 FlaG protein zf-C2H2_4 PF13894.6 ORX97582.1 - 3.3e-13 49.3 14.6 0.00051 20.6 2.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORX97582.1 - 1e-12 47.8 17.6 0.0006 20.1 0.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97582.1 - 3.1e-12 46.3 4.2 3.4e-07 30.4 0.8 3.4 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORX97582.1 - 1.4e-05 25.3 1.6 0.78 10.1 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX97582.1 - 5.1e-05 23.2 9.9 0.26 11.3 0.9 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORX97582.1 - 0.0014 18.5 1.0 0.0014 18.5 1.0 3.3 3 2 0 3 3 3 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 ORX97582.1 - 0.0014 18.7 5.9 0.0026 17.9 3.4 2.3 2 1 1 3 3 3 1 Zinc ribbon domain zf_UBZ PF18439.1 ORX97582.1 - 0.0018 17.8 3.3 0.23 11.1 0.4 2.6 3 0 0 3 3 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 ORX97582.1 - 0.003 17.3 13.2 0.39 10.5 1.6 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_ZIC PF18366.1 ORX97582.1 - 0.0093 16.1 5.2 0.37 10.9 0.2 2.9 1 1 2 3 3 3 1 Zic proteins zinc finger domain YhfH PF14149.6 ORX97582.1 - 0.012 15.6 0.2 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-RING_7 PF02591.15 ORX97582.1 - 0.015 15.5 0.9 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain HypA PF01155.19 ORX97582.1 - 0.023 14.7 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 ORX97582.1 - 0.031 14.3 4.5 2.4 8.2 0.7 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_8 PF15909.5 ORX97582.1 - 0.033 14.5 2.8 0.035 14.4 1.5 1.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon IBR PF01485.21 ORX97582.1 - 0.037 14.2 3.7 0.35 11.1 3.7 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 ORX97582.1 - 0.05 13.5 2.3 1.3 8.9 0.5 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-met PF12874.7 ORX97582.1 - 0.053 13.9 3.9 5.4 7.5 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-ribbon_3 PF13248.6 ORX97582.1 - 0.071 12.5 6.5 2 7.9 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-LYAR PF08790.11 ORX97582.1 - 0.086 12.8 4.9 4.7 7.2 1.6 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORX97582.1 - 0.12 12.7 2.8 19 5.7 0.0 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 ORX97582.1 - 0.15 11.7 2.9 0.26 10.9 0.4 2.3 2 1 1 3 3 3 0 MYST family zinc finger domain DUF3268 PF11672.8 ORX97582.1 - 0.16 12.3 1.2 0.18 12.1 0.2 1.6 1 1 1 2 2 2 0 zinc-finger-containing domain zf-C2HE PF16278.5 ORX97582.1 - 0.19 12.2 0.7 0.19 12.2 0.7 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2256 PF10013.9 ORX97582.1 - 0.24 11.6 2.2 3.6 7.8 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_SprT PF17283.2 ORX97582.1 - 0.24 11.3 6.9 2 8.4 0.6 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 ORX97582.1 - 0.31 11.7 3.3 0.43 11.3 1.3 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 ORX97582.1 - 0.35 11.2 7.8 3.8 7.9 0.0 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.21 ORX97582.1 - 0.42 10.8 5.1 0.86 9.8 1.4 2.3 1 1 1 2 2 2 0 FYVE zinc finger zf-FPG_IleRS PF06827.14 ORX97582.1 - 0.48 10.3 8.3 1.9 8.4 0.1 2.5 3 0 0 3 3 2 0 Zinc finger found in FPG and IleRS zf-AN1 PF01428.16 ORX97582.1 - 0.52 10.5 13.0 17 5.7 0.6 3.1 1 1 1 2 2 2 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.7 ORX97582.1 - 1.9 8.5 7.7 12 6.0 2.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Dynamin_M PF01031.20 ORX97583.1 - 1.2e-101 339.7 0.0 1.2e-101 339.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORX97583.1 - 4.7e-55 186.2 0.1 1e-54 185.1 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORX97583.1 - 3.7e-29 100.7 5.0 3.7e-29 100.7 5.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORX97583.1 - 0.00031 20.8 0.5 0.0018 18.3 0.5 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Strep_SA_rep PF06696.11 ORX97583.1 - 0.079 13.0 3.7 0.23 11.5 3.7 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat AAA_16 PF13191.6 ORX97583.1 - 0.088 13.2 0.0 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 ORX97583.1 - 0.16 11.6 8.4 2 8.0 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain SUKH_5 PF14567.6 ORX97584.1 - 0.00086 19.1 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SMI1_KNR4 PF09346.10 ORX97584.1 - 0.007 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORX97584.1 - 0.0087 16.5 0.1 0.02 15.3 0.1 1.7 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall Pkinase PF00069.25 ORX97585.1 - 1.1e-26 93.7 0.0 1.4e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97585.1 - 3.6e-10 39.6 0.0 4.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX97585.1 - 3.5e-07 29.4 0.0 4.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX97585.1 - 0.18 11.7 0.0 0.92 9.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 ORX97586.1 - 1.2e-13 50.7 18.1 1e-05 25.7 2.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97586.1 - 2.6e-13 49.7 9.8 7.7e-08 32.4 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX97586.1 - 7.7e-11 41.9 14.5 7.5e-05 23.2 1.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX97586.1 - 1.6e-06 28.2 3.5 0.0015 18.8 0.9 3.3 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX97586.1 - 2e-06 27.6 7.0 0.25 11.4 1.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORX97586.1 - 3.1e-05 23.6 9.4 0.043 13.6 0.7 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 ORX97586.1 - 0.00023 21.4 3.5 0.00037 20.7 3.0 1.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf_ZIC PF18366.1 ORX97586.1 - 0.00061 19.8 6.8 0.06 13.5 0.9 2.6 2 1 1 3 3 3 2 Zic proteins zinc finger domain zf-LYAR PF08790.11 ORX97586.1 - 0.0016 18.3 5.5 4.8 7.2 0.2 3.1 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-met PF12874.7 ORX97586.1 - 0.0019 18.5 6.9 0.015 15.6 0.7 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORX97586.1 - 0.003 17.6 5.1 1.2 9.3 0.2 3.1 3 0 0 3 3 3 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 ORX97586.1 - 0.0043 17.7 3.2 0.012 16.3 1.1 2.1 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 ORX97586.1 - 0.01 16.3 6.8 0.092 13.2 1.5 2.6 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 ORX97586.1 - 0.011 15.8 1.8 0.014 15.4 1.8 1.3 1 1 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 ORX97586.1 - 0.011 15.7 0.7 5 7.2 0.0 2.6 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 ORX97586.1 - 0.023 14.6 5.6 0.39 10.7 0.3 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 ORX97586.1 - 0.026 14.1 1.1 7.5 6.2 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-MYST PF17772.1 ORX97586.1 - 0.036 13.7 1.9 0.057 13.0 0.3 2.1 2 1 1 3 3 3 0 MYST family zinc finger domain HypA PF01155.19 ORX97586.1 - 0.088 12.8 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 ORX97586.1 - 0.1 12.5 2.6 2 8.4 0.2 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain C1_2 PF03107.16 ORX97586.1 - 0.19 12.0 4.6 1.9 8.9 4.6 2.2 1 1 0 1 1 1 0 C1 domain IBR PF01485.21 ORX97586.1 - 0.27 11.5 5.6 2 8.7 5.6 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DM PF00751.18 ORX97586.1 - 0.4 10.6 9.5 0.055 13.4 4.7 2.0 2 1 0 2 2 2 0 DM DNA binding domain zf-AN1 PF01428.16 ORX97586.1 - 0.82 9.9 12.5 13 6.0 6.7 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger FYVE PF01363.21 ORX97586.1 - 1.6 8.9 7.7 1.8 8.7 2.3 2.2 1 1 1 2 2 2 0 FYVE zinc finger COX14 PF14880.6 ORX97587.1 - 1.7e-08 34.2 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF2530 PF10745.9 ORX97587.1 - 0.034 14.4 0.1 0.04 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) TauD PF02668.16 ORX97588.1 - 9.6e-43 146.9 0.1 1.3e-42 146.4 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORX97588.1 - 5.5e-10 39.7 0.4 2.3e-09 37.7 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORX97588.1 - 7.1e-06 25.3 0.2 0.0012 18.1 0.0 3.3 2 2 2 4 4 4 1 CsiD DUF2396 PF09654.10 ORX97588.1 - 0.016 15.3 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) EF-hand_10 PF14788.6 ORX97588.1 - 0.038 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 EF hand VPS9 PF02204.18 ORX97589.1 - 5.6e-25 87.6 0.2 1.5e-24 86.2 0.1 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MCH PF02289.16 ORX97589.1 - 0.033 13.5 0.3 0.092 12.0 0.1 1.7 2 0 0 2 2 2 0 Cyclohydrolase (MCH) SRA1 PF07304.11 ORX97589.1 - 0.18 11.6 2.2 0.23 11.2 0.1 2.2 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) PAP2_C PF14360.6 ORX97590.1 - 0.0079 16.7 2.6 0.011 16.2 2.6 1.2 1 0 0 1 1 1 1 PAP2 superfamily C-terminal CBM9_1 PF06452.11 ORX97591.1 - 4.7e-13 49.5 1.7 1.3e-12 48.0 0.1 2.2 3 0 0 3 3 3 1 Carbohydrate family 9 binding domain-like Pilin_GH PF16734.5 ORX97591.1 - 0.22 11.8 0.1 0.51 10.7 0.1 1.6 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative ADH_zinc_N PF00107.26 ORX97592.1 - 9.7e-34 116.1 0.6 1.6e-33 115.4 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX97592.1 - 3.3e-14 54.1 0.0 5.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORX97592.1 - 3.2e-12 46.3 0.0 8.9e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ORX97592.1 - 0.00041 19.7 0.4 0.0007 18.9 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX97592.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX97592.1 - 0.078 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Tn7_Tnp_TnsA_C PF08721.11 ORX97593.1 - 0.0015 19.1 0.1 0.0015 19.1 0.1 3.8 3 1 2 5 5 5 1 TnsA endonuclease C terminal PRKCSH-like PF12999.7 ORX97593.1 - 1.7 8.4 7.4 0.73 9.6 3.8 2.1 1 1 0 2 2 2 0 Glucosidase II beta subunit-like Spectrin PF00435.21 ORX97593.1 - 7.9 7.0 32.6 1 9.9 3.8 3.6 2 1 2 4 4 4 0 Spectrin repeat Maf1 PF09174.10 ORX97594.1 - 1.2e-58 198.1 0.3 1.6e-58 197.7 0.3 1.2 1 0 0 1 1 1 1 Maf1 regulator Lipase_3 PF01764.25 ORX97624.1 - 8.9e-16 58.0 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 ORX97624.1 - 0.006 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.8 ORX97624.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) UPF0227 PF05728.12 ORX97624.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C2H2 PF00096.26 ORX97625.1 - 6.5e-14 51.5 19.9 5.1e-06 26.7 0.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97625.1 - 1.9e-11 43.8 16.6 2.5e-06 27.6 2.6 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX97625.1 - 3e-11 43.2 18.3 0.00063 20.4 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX97625.1 - 2.5e-07 30.8 12.7 7.5e-05 22.9 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORX97625.1 - 0.0022 18.3 12.2 0.0032 17.7 3.9 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 ORX97625.1 - 0.014 15.7 14.4 1.5 9.2 0.9 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORX97625.1 - 0.014 15.3 0.9 0.014 15.3 0.9 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 ORX97625.1 - 0.034 14.5 15.7 0.043 14.2 1.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX97625.1 - 0.037 13.9 12.2 0.29 11.1 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger LIM PF00412.22 ORX97625.1 - 0.082 13.2 8.3 0.41 10.9 8.2 2.0 1 1 1 2 2 2 0 LIM domain zinc_ribbon_9 PF14369.6 ORX97625.1 - 0.11 12.7 8.6 0.19 12.0 1.4 2.9 3 0 0 3 3 3 0 zinc-ribbon Sprouty PF05210.13 ORX97625.1 - 0.31 11.5 6.4 0.37 11.2 6.4 1.1 1 0 0 1 1 1 0 Sprouty protein (Spry) HNH_5 PF14279.6 ORX97625.1 - 1.9 8.4 9.5 3.1 7.7 1.0 3.0 2 1 0 2 2 2 0 HNH endonuclease zinc_ribbon_12 PF11331.8 ORX97625.1 - 9.4 6.1 9.3 0.082 12.7 1.1 1.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain Pkinase PF00069.25 ORX97626.1 - 1.3e-70 237.8 0.0 2e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97626.1 - 3.4e-39 134.7 0.0 6.8e-39 133.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORX97626.1 - 2.1e-15 56.2 0.1 3.7e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORX97626.1 - 1.4e-08 34.4 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORX97626.1 - 5.3e-05 22.3 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX97626.1 - 0.00056 19.3 0.3 0.00095 18.6 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORX97626.1 - 0.0028 17.6 0.0 0.021 14.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORX97626.1 - 0.06 12.1 1.0 0.37 9.5 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 ORX97626.1 - 0.066 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Fasciclin PF02469.22 ORX97627.1 - 1.1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain PX PF00787.24 ORX97629.1 - 1.6e-05 24.9 0.0 5.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 PX domain Fz PF01392.22 ORX97630.1 - 0.011 16.4 1.2 0.016 15.8 1.2 1.3 1 0 0 1 1 1 0 Fz domain NAM-associated PF14303.6 ORX97630.1 - 0.17 12.6 0.1 0.23 12.2 0.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GPI-anchored PF10342.9 ORX97632.1 - 4.4e-14 53.0 0.0 9.5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Abhydrolase_1 PF00561.20 ORX97633.1 - 2e-50 171.8 0.0 2.4e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX97633.1 - 0.0066 17.1 0.0 0.0087 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sulfate_transp PF00916.20 ORX97634.1 - 1.6e-100 336.5 24.3 2.1e-100 336.1 24.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORX97634.1 - 6.5e-15 54.8 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.6 ORX97634.1 - 0.014 15.0 0.9 0.031 13.9 0.9 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF5543 PF17697.1 ORX97635.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5543) Protoglobin PF11563.8 ORX97641.1 - 3.9e-15 56.1 0.0 4.5e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Protoglobin MFS_1 PF07690.16 ORX97643.1 - 3.4e-30 105.2 55.6 3.8e-29 101.7 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORX97643.1 - 0.00013 20.9 30.8 0.032 13.1 12.7 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter RGP PF03214.13 ORX97643.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide MFS_4 PF06779.14 ORX97643.1 - 0.3 10.3 25.3 1.1 8.4 25.3 1.9 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB GFO_IDH_MocA PF01408.22 ORX97644.1 - 6.3e-15 56.1 0.0 9.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORX97644.1 - 2.4e-08 34.0 0.0 3.6e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Tim44 PF04280.15 ORX97645.1 - 7.7e-32 110.4 3.4 8.5e-32 110.3 0.1 2.5 2 1 1 3 3 3 1 Tim44-like domain PhaP_Bmeg PF09602.10 ORX97645.1 - 0.004 17.1 5.7 0.013 15.4 5.7 1.9 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ECH_2 PF16113.5 ORX97645.1 - 0.047 13.2 8.5 0.06 12.8 5.6 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CutA1 PF03091.15 ORX97645.1 - 0.06 13.2 0.0 0.29 11.0 0.0 2.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Histidinol_dh PF00815.20 ORX97645.1 - 0.25 10.3 5.0 0.47 9.4 5.0 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase DnaI_N PF07319.11 ORX97645.1 - 0.64 10.7 5.9 8.1 7.2 0.0 3.3 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Allexi_40kDa PF05549.11 ORX97645.1 - 0.66 9.4 3.3 1.2 8.6 3.3 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein Pex19 PF04614.12 ORX97645.1 - 1.8 8.3 14.4 0.86 9.3 11.4 1.8 1 1 1 2 2 2 0 Pex19 protein family DUF948 PF06103.11 ORX97645.1 - 2.7 8.3 7.4 1.8 8.9 2.6 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 ORX97646.1 - 4.6e-68 229.4 0.0 2.1e-58 197.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97646.1 - 2.3e-39 135.3 0.0 1.3e-35 123.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX97646.1 - 2.4e-09 36.9 0.0 3.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX97646.1 - 1.8e-05 23.7 0.3 3.8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX97646.1 - 0.0019 18.2 0.6 0.0039 17.2 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX97646.1 - 0.039 13.3 0.5 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORX97646.1 - 0.056 13.0 0.3 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 ORX97646.1 - 0.095 12.3 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PDEase_I PF00233.19 ORX97647.1 - 6.6e-71 238.8 2.2 8.6e-71 238.4 2.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 ORX97647.1 - 0.017 15.3 0.1 0.044 14.0 0.1 1.7 1 0 0 1 1 1 0 HD domain Radical_SAM_C PF16199.5 ORX97648.1 - 1.3e-33 114.8 0.0 7e-33 112.5 0.0 2.1 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ORX97648.1 - 4.1e-18 66.3 0.4 1.2e-17 64.8 0.1 1.9 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ORX97648.1 - 4.5e-10 39.8 0.0 9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX97648.1 - 2.1e-06 27.7 0.1 4.4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX97648.1 - 0.00052 20.4 0.1 0.0011 19.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX97648.1 - 0.023 14.7 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Spo12 PF05032.12 ORX97649.1 - 7.5e-10 38.5 1.8 7.5e-10 38.5 1.8 1.8 2 0 0 2 2 2 1 Spo12 family CaM_binding PF07839.11 ORX97649.1 - 0.023 15.4 0.0 0.027 15.2 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain VMA21 PF09446.10 ORX97651.1 - 0.00099 19.2 12.6 0.0047 17.0 12.6 1.8 1 1 0 1 1 1 1 VMA21-like domain CRPA PF05745.11 ORX97651.1 - 0.021 14.8 0.4 0.025 14.6 0.4 1.1 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pkinase PF00069.25 ORX97652.1 - 6.8e-68 228.9 0.0 8e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97652.1 - 5.5e-27 94.7 0.0 8.1e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX97652.1 - 4e-05 23.1 0.0 0.0039 16.6 0.0 2.4 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 ORX97652.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 ORX97652.1 - 0.013 15.5 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORX97652.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX97652.1 - 0.066 12.8 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 ORX97652.1 - 0.099 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Kinesin PF00225.23 ORX97653.1 - 2.4e-112 375.2 0.8 2.4e-112 375.2 0.8 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORX97653.1 - 3.7e-29 101.6 0.3 3.7e-29 101.6 0.3 3.4 3 1 0 3 3 3 1 Microtubule binding DUF3584 PF12128.8 ORX97653.1 - 0.00053 17.7 39.8 0.00053 17.7 39.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 ORX97653.1 - 0.00091 18.2 11.3 0.00091 18.2 11.3 4.9 2 2 3 5 5 5 3 Spc7 kinetochore protein Abhydrolase_8 PF06259.12 ORX97653.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase HAP1_N PF04849.13 ORX97653.1 - 0.0047 16.2 24.9 0.0047 16.2 24.9 4.2 2 2 2 4 4 4 1 HAP1 N-terminal conserved region FUSC PF04632.12 ORX97653.1 - 1.6 7.2 23.1 0.033 12.7 8.5 2.8 1 1 1 3 3 3 0 Fusaric acid resistance protein family Porin_3 PF01459.22 ORX97654.1 - 6.2e-81 271.8 0.6 7e-81 271.6 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin AAA PF00004.29 ORX97655.1 - 1.6e-44 151.5 0.2 8.2e-44 149.2 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX97655.1 - 1.7e-10 40.5 0.1 4.1e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORX97655.1 - 1e-09 38.2 0.3 6.3e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORX97655.1 - 2.3e-08 34.1 0.1 7e-08 32.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX97655.1 - 3.5e-08 34.0 0.1 2.9e-05 24.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 ORX97655.1 - 8.3e-08 32.5 0.0 2.6e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORX97655.1 - 2.6e-06 26.8 0.2 6.4e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORX97655.1 - 5.3e-05 23.5 1.1 0.01 16.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 ORX97655.1 - 0.0002 21.3 0.0 0.015 15.3 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORX97655.1 - 0.00028 21.5 0.1 0.003 18.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 ORX97655.1 - 0.00028 21.2 0.2 0.00061 20.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ORX97655.1 - 0.00041 20.1 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ORX97655.1 - 0.00062 19.7 0.0 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 ORX97655.1 - 0.0022 18.2 0.1 0.013 15.6 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 ORX97655.1 - 0.0022 17.6 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 ORX97655.1 - 0.0023 17.7 0.1 0.0057 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORX97655.1 - 0.0026 18.1 0.0 0.0066 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 ORX97655.1 - 0.0028 17.7 0.0 0.0082 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 ORX97655.1 - 0.0069 15.8 0.0 0.53 9.7 0.0 2.6 3 0 0 3 3 2 1 Bacterial TniB protein AAA_3 PF07726.11 ORX97655.1 - 0.0076 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORX97655.1 - 0.0083 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 ORX97655.1 - 0.011 15.7 1.6 0.3 10.9 0.0 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 ORX97655.1 - 0.015 15.1 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORX97655.1 - 0.018 14.8 0.1 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 ORX97655.1 - 0.019 14.2 0.0 0.058 12.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 ORX97655.1 - 0.02 14.8 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 ORX97655.1 - 0.022 14.5 0.2 0.048 13.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX97655.1 - 0.039 13.5 0.4 0.19 11.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX97655.1 - 0.045 14.1 0.2 0.14 12.4 0.1 1.8 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.18 ORX97655.1 - 0.05 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 ORX97655.1 - 0.093 12.4 0.1 1.2 8.8 0.0 2.6 3 1 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.19 ORX97655.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CAP59_mtransfer PF11735.8 ORX97655.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 AAA_29 PF13555.6 ORX97655.1 - 0.2 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORX97655.1 - 0.48 10.9 5.0 2.7 8.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain Hexapep PF00132.24 ORX97656.1 - 7.4e-05 22.3 23.1 0.014 15.1 1.0 4.6 3 2 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORX97656.1 - 0.043 13.6 1.3 0.043 13.6 1.3 4.1 3 1 2 5 5 5 0 Hexapeptide repeat of succinyl-transferase MoaC PF01967.21 ORX97657.1 - 5.9e-54 181.8 1.6 7.1e-54 181.6 1.6 1.1 1 0 0 1 1 1 1 MoaC family Mig-14 PF07395.11 ORX97657.1 - 0.066 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Mig-14 DNA_pol3_beta PF00712.19 ORX97657.1 - 0.14 12.3 0.2 0.21 11.7 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain DUF150 PF02576.17 ORX97657.1 - 0.15 12.5 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 RimP N-terminal domain Ribosomal_L44 PF00935.19 ORX97658.1 - 3.9e-37 126.6 11.0 5.7e-37 126.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_S25 PF03297.15 ORX97659.1 - 2.2e-35 120.9 0.2 2.4e-35 120.7 0.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 ORX97659.1 - 0.0045 16.9 0.1 0.0054 16.6 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_CodY PF08222.11 ORX97659.1 - 0.011 15.3 0.8 0.014 14.9 0.1 1.5 2 0 0 2 2 2 0 CodY helix-turn-helix domain EAP30 PF04157.16 ORX97659.1 - 0.087 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_24 PF13412.6 ORX97659.1 - 0.1 12.2 0.3 0.17 11.5 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Mid2 PF04478.12 ORX97660.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PAP2 PF01569.21 ORX97661.1 - 1.9e-32 111.9 1.2 1.9e-32 111.9 1.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX97661.1 - 5.9e-07 29.4 8.0 1.4e-06 28.1 5.7 2.4 1 1 1 2 2 2 1 PAP2 superfamily DUF420 PF04238.12 ORX97661.1 - 0.033 14.5 0.2 0.078 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF420) FeoB_associated PF12669.7 ORX97661.1 - 0.054 13.9 0.1 17 5.9 0.0 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF5510 PF17629.2 ORX97661.1 - 0.097 12.6 0.7 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) DUF687 PF05095.12 ORX97661.1 - 0.16 10.4 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) PAP2_C PF14360.6 ORX97661.1 - 2.1 9.0 5.8 0.3 11.7 0.7 2.1 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Got1 PF04178.12 ORX97662.1 - 1.1e-17 64.4 13.5 1.4e-17 64.2 13.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Pex2_Pex12 PF04757.14 ORX97663.1 - 1.1e-54 185.4 6.8 1.3e-54 185.2 6.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 ORX97663.1 - 2.1e-05 24.3 4.6 3.7e-05 23.5 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX97663.1 - 0.00048 19.9 7.0 0.00079 19.2 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX97663.1 - 0.00093 19.0 5.3 0.0017 18.2 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX97663.1 - 0.012 15.9 5.6 0.023 15.0 5.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 ORX97663.1 - 0.035 14.1 8.3 0.072 13.1 8.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORX97663.1 - 0.045 13.9 8.3 0.094 12.9 8.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING U-box PF04564.15 ORX97663.1 - 0.073 13.3 0.0 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 U-box domain Prok-RING_4 PF14447.6 ORX97663.1 - 0.54 10.2 3.6 1.1 9.2 3.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MTHFR PF02219.17 ORX97664.1 - 4.4e-122 406.9 0.0 5.7e-122 406.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase BUD22 PF09073.10 ORX97665.1 - 0.007 15.8 32.7 0.011 15.1 32.7 1.2 1 0 0 1 1 1 1 BUD22 UTP15_C PF09384.10 ORX97665.1 - 0.019 14.6 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 UTP15 C terminal Nop53 PF07767.11 ORX97665.1 - 0.029 13.8 32.3 0.052 12.9 32.3 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 ORX97665.1 - 0.21 10.7 25.6 0.34 10.0 25.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 ORX97665.1 - 0.25 10.9 21.6 0.49 9.9 21.6 1.5 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 ORX97665.1 - 0.87 9.0 36.9 1.4 8.3 36.9 1.2 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.18 ORX97665.1 - 1.1 9.1 19.3 1.9 8.3 19.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 ORX97665.1 - 2.8 6.1 38.3 4.5 5.4 38.3 1.2 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 ORX97665.1 - 3.2 7.6 24.4 6 6.6 24.4 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rtf2 PF04641.12 ORX97666.1 - 1.8e-73 247.2 1.1 2e-73 247.0 1.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 ORX97666.1 - 0.00025 21.1 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 ORX97666.1 - 0.0028 17.4 1.8 0.053 13.4 0.0 2.8 3 1 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit PPR_2 PF13041.6 ORX97667.1 - 2e-226 732.3 47.7 3.2e-16 59.2 0.3 28.4 7 5 21 28 28 28 28 PPR repeat family PPR PF01535.20 ORX97667.1 - 9.1e-156 495.7 37.8 6.1e-07 29.3 0.1 28.9 28 0 0 28 28 28 26 PPR repeat PPR_1 PF12854.7 ORX97667.1 - 6.4e-146 473.7 0.8 1.6e-08 34.1 0.0 25.8 27 0 0 27 27 26 21 PPR repeat PPR_3 PF13812.6 ORX97667.1 - 1.6e-129 422.0 30.7 2.6e-13 49.8 1.9 19.1 13 5 6 20 20 19 19 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX97667.1 - 1.3e-78 263.2 19.8 2.6e-10 40.0 0.2 10.2 2 2 9 11 11 11 11 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX97667.1 - 2e-15 56.1 2.0 14 6.8 0.0 14.1 12 4 5 17 17 13 0 Tetratricopeptide repeat RPM2 PF08579.11 ORX97667.1 - 1e-12 48.5 28.1 0.26 11.7 0.3 13.4 8 5 4 12 12 12 4 Mitochondrial ribonuclease P subunit (RPM2) COesterase PF00135.28 ORX97667.1 - 1.8e-08 33.7 0.1 5.3e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family TPR_16 PF13432.6 ORX97667.1 - 4.7e-06 27.1 0.2 1.2 9.9 0.1 7.5 9 1 1 10 10 7 1 Tetratricopeptide repeat RabGAP-TBC PF00566.18 ORX97667.1 - 1.5e-05 24.7 1.8 14 5.3 0.0 6.1 7 0 0 7 7 7 0 Rab-GTPase-TBC domain Peptidase_S9 PF00326.21 ORX97667.1 - 2e-05 24.2 0.1 0.00027 20.5 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family MRP-S27 PF10037.9 ORX97667.1 - 0.00031 19.7 15.0 0.036 12.9 0.0 6.0 5 2 2 8 8 8 3 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.11 ORX97667.1 - 0.0011 18.1 7.7 10 5.1 0.9 6.8 6 3 0 7 7 6 0 Evolutionarily conserved signalling intermediate in Toll pathway Hydrolase_4 PF12146.8 ORX97667.1 - 0.0016 17.7 0.1 0.032 13.5 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 RPN7 PF10602.9 ORX97667.1 - 0.0023 17.7 12.4 9.9 5.8 0.0 8.6 7 5 4 12 12 12 0 26S proteasome subunit RPN7 Abhydrolase_3 PF07859.13 ORX97667.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold DASH_Ask1 PF08655.10 ORX97667.1 - 0.02 14.8 0.8 7.9 6.5 0.1 4.8 4 0 0 4 4 4 0 DASH complex subunit Ask1 TPR_1 PF00515.28 ORX97667.1 - 0.022 14.6 9.9 8.8 6.3 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.16 ORX97667.1 - 0.022 15.4 0.3 11 6.8 0.0 5.1 5 1 0 5 5 5 0 Peptidase inhibitor I9 TPR_12 PF13424.6 ORX97667.1 - 0.029 14.6 2.2 7.5 6.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX97667.1 - 0.042 13.9 14.3 8.8 6.6 0.0 8.8 12 1 1 13 13 8 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 ORX97667.1 - 0.055 13.3 0.1 1.4 8.7 0.0 3.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Vps39_1 PF10366.9 ORX97667.1 - 0.056 13.7 4.4 27 5.1 0.0 4.8 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 SPOB_a PF14689.6 ORX97667.1 - 0.15 11.8 7.9 9.8 6.0 0.0 6.1 8 0 0 8 8 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_11 PF13414.6 ORX97667.1 - 2.2 8.0 3.9 45 3.8 0.5 4.2 4 0 0 4 4 3 0 TPR repeat Clathrin PF00637.20 ORX97667.1 - 2.4 8.0 12.4 50 3.7 0.0 6.8 6 2 2 8 8 7 0 Region in Clathrin and VPS tRNA-synt_2 PF00152.20 ORX97668.1 - 1.1e-94 317.1 0.0 1.8e-94 316.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORX97668.1 - 1.3e-09 37.9 0.0 3.7e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4661 PF15576.6 ORX97668.1 - 0.061 13.2 2.0 0.1 12.5 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Vfa1 PF08432.10 ORX97668.1 - 1.9 8.8 9.1 3.1 8.1 9.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Myticin-prepro PF10690.9 ORX97673.1 - 0.044 14.0 0.2 0.064 13.5 0.2 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Cytidylate_kin PF02224.18 ORX97696.1 - 1.1e-67 227.8 1.3 1.4e-67 227.5 1.3 1.1 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 ORX97696.1 - 2.4e-05 24.5 0.1 0.015 15.4 0.0 2.3 2 0 0 2 2 2 2 Cytidylate kinase-like family dNK PF01712.19 ORX97696.1 - 2.7e-05 24.1 0.3 0.13 12.1 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 ORX97696.1 - 4.8e-05 23.9 0.1 0.0017 18.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORX97696.1 - 0.00069 20.0 0.5 0.11 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 ORX97696.1 - 0.0013 18.9 0.7 0.02 15.0 0.1 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 ORX97696.1 - 0.0042 17.3 0.6 0.021 15.0 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORX97696.1 - 0.099 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 ORX97696.1 - 0.12 11.3 0.2 0.25 10.3 0.1 1.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF3421 PF11901.8 ORX97697.1 - 1.2e-28 99.4 0.1 3.7e-19 68.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Cupin_8 PF13621.6 ORX97698.1 - 5.2e-43 147.6 0.0 6.4e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORX97698.1 - 1.5e-10 41.0 0.0 3.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 ORX97698.1 - 0.00024 21.5 0.0 0.0004 20.8 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ORX97698.1 - 0.00036 20.2 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain LRR_6 PF13516.6 ORX97699.1 - 4.9e-12 44.9 19.9 0.0055 16.7 0.0 8.7 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 ORX97699.1 - 6.6e-05 23.2 16.0 0.0058 17.0 0.0 6.0 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX97699.1 - 0.0031 17.9 5.6 67 4.6 0.1 7.0 7 1 0 7 7 7 0 Leucine Rich Repeat FA_hydroxylase PF04116.13 ORX97700.1 - 1e-24 87.4 18.8 1e-24 87.4 18.8 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-FCS PF06467.14 ORX97700.1 - 0.075 13.0 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HEAT PF02985.22 ORX97701.1 - 1.3e-10 40.5 5.8 0.19 12.1 0.1 8.1 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 ORX97701.1 - 1.9e-09 37.8 0.0 0.0085 16.5 0.0 5.4 5 2 1 6 6 6 3 HEAT repeats CLASP_N PF12348.8 ORX97701.1 - 8.7e-06 25.5 0.4 0.069 12.7 0.0 5.2 5 0 0 5 5 5 1 CLASP N terminal Cnd1 PF12717.7 ORX97701.1 - 5.5e-05 23.3 3.6 0.56 10.2 0.0 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 ORX97701.1 - 0.0093 16.0 0.1 0.23 11.5 0.1 3.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Acyl-CoA_dh_1 PF00441.24 ORX97702.1 - 5e-42 143.6 0.1 9.4e-42 142.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORX97702.1 - 5.2e-40 136.6 0.0 9.6e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORX97702.1 - 4.6e-27 94.1 0.0 8.5e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORX97702.1 - 6e-13 49.2 0.0 1.4e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORX97703.1 - 7.6e-27 94.4 0.1 1e-26 94.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORX97703.1 - 5.1e-14 52.6 0.0 1.9e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORX97703.1 - 6e-09 36.4 0.0 1.7e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORX97703.1 - 2.4e-07 30.9 0.0 4.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORX97703.1 - 6e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORX97703.1 - 0.00011 21.9 0.3 0.00075 19.1 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 ORX97703.1 - 0.00055 20.2 0.1 0.0012 19.1 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 ORX97703.1 - 0.0047 17.6 0.2 0.01 16.5 0.2 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ApbA PF02558.16 ORX97703.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 ORX97703.1 - 0.029 15.2 0.0 0.07 14.0 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold tRNA_m1G_MT PF01746.21 ORX97703.1 - 0.085 12.6 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 tRNA (Guanine-1)-methyltransferase UDPG_MGDP_dh_N PF03721.14 ORX97703.1 - 0.1 12.1 0.4 0.28 10.7 0.4 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SWIB PF02201.18 ORX97704.1 - 0.0014 18.4 0.1 0.079 12.8 0.1 2.8 1 1 0 1 1 1 1 SWIB/MDM2 domain PH PF00169.29 ORX97704.1 - 0.019 15.5 0.0 0.055 14.0 0.0 1.9 1 0 0 1 1 1 0 PH domain DUF5098 PF17023.5 ORX97704.1 - 0.69 8.8 7.7 0.047 12.6 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5098) SE PF08491.10 ORX97705.1 - 5.2e-104 347.2 0.0 7.7e-104 346.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ORX97705.1 - 2.1e-12 46.9 0.0 3.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORX97705.1 - 1.4e-05 24.9 0.0 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX97705.1 - 6.5e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX97705.1 - 6.6e-05 22.2 0.5 0.00018 20.7 0.5 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 ORX97705.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ORX97705.1 - 0.0014 17.8 0.1 0.021 13.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ORX97705.1 - 0.0037 16.4 0.2 3.9 6.4 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 ORX97705.1 - 0.013 16.1 0.1 0.071 13.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORX97705.1 - 0.014 14.3 0.5 5.4 5.7 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.16 ORX97705.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ORX97705.1 - 0.042 13.2 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORX97705.1 - 0.042 12.5 0.0 0.066 11.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 ORX97705.1 - 0.045 13.0 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORX97705.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 ORX97705.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 ORX97705.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 ORX97705.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ORX97705.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FA_hydroxylase PF04116.13 ORX97706.1 - 2.5e-25 89.3 20.1 2.5e-25 89.3 20.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3989 PF13150.6 ORX97706.1 - 4.5 7.1 5.8 4.5 7.1 2.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3989) TatC PF00902.18 ORX97706.1 - 5.1 6.9 10.9 3.2 7.5 4.1 2.4 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) PCI PF01399.27 ORX97707.1 - 9e-13 48.6 0.1 3.8e-12 46.6 0.1 2.1 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 ORX97707.1 - 2e-07 30.5 2.8 5.5e-07 29.1 2.8 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix Mvb12 PF09452.10 ORX97707.1 - 0.026 15.0 1.4 2 8.9 0.0 3.4 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 BLOC1_2 PF10046.9 ORX97708.1 - 0.0021 18.3 4.3 0.0089 16.3 1.1 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 KBP_C PF12309.8 ORX97708.1 - 0.0082 15.7 0.5 0.01 15.4 0.5 1.1 1 0 0 1 1 1 1 KIF-1 binding protein C terminal CENP-F_leu_zip PF10473.9 ORX97708.1 - 0.0095 16.0 3.3 0.013 15.6 3.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 ORX97708.1 - 0.012 16.4 1.9 4.9 8.1 0.0 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 ORX97708.1 - 0.018 15.0 4.2 0.074 13.1 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 ORX97708.1 - 0.021 14.8 3.1 0.058 13.3 1.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.6 ORX97708.1 - 0.022 15.2 2.8 0.46 10.9 0.2 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 ORX97708.1 - 0.029 14.9 1.5 0.066 13.8 1.5 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal HMMR_N PF15905.5 ORX97708.1 - 0.031 13.8 4.4 0.038 13.5 4.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 ORX97708.1 - 0.034 14.6 1.5 0.18 12.2 1.5 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 ORX97708.1 - 0.041 12.8 2.9 0.06 12.2 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 ORX97708.1 - 0.045 13.6 0.6 0.062 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_HK97_TLTM PF06120.11 ORX97708.1 - 0.046 12.9 5.9 0.25 10.5 5.9 1.8 1 1 0 1 1 1 0 Tail length tape measure protein Helo_like_N PF17111.5 ORX97708.1 - 0.048 13.0 2.1 0.076 12.4 1.0 1.7 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins PilJ PF13675.6 ORX97708.1 - 0.048 13.7 1.4 0.06 13.4 0.5 1.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.10 ORX97708.1 - 0.05 13.8 0.1 0.083 13.1 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 ORX97708.1 - 0.051 13.6 0.7 0.051 13.6 0.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding PCRF PF03462.18 ORX97708.1 - 0.058 13.3 2.8 0.08 12.8 2.8 1.2 1 0 0 1 1 1 0 PCRF domain WXG100 PF06013.12 ORX97708.1 - 0.06 13.6 1.4 1.7 8.9 0.1 2.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 ORX97708.1 - 0.069 13.4 2.2 0.11 12.7 2.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CheZ PF04344.13 ORX97708.1 - 0.075 12.9 1.2 0.11 12.4 1.2 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ CDH1_2_SANT_HL1 PF18375.1 ORX97708.1 - 0.088 13.5 0.4 0.25 12.0 0.2 1.8 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 PspA_IM30 PF04012.12 ORX97708.1 - 0.11 12.1 4.5 0.63 9.6 0.5 2.1 1 1 1 2 2 2 0 PspA/IM30 family ATG16 PF08614.11 ORX97708.1 - 0.14 12.4 5.2 0.21 11.8 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Sec34 PF04136.15 ORX97708.1 - 0.32 10.9 4.7 0.93 9.4 4.6 1.7 1 1 0 1 1 1 0 Sec34-like family UPF0449 PF15136.6 ORX97708.1 - 0.5 10.9 3.8 2.4 8.7 3.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Syntaxin_2 PF14523.6 ORX97708.1 - 1.1 9.7 5.7 4 7.9 2.7 2.4 2 1 0 2 2 2 0 Syntaxin-like protein zf-C4H2 PF10146.9 ORX97708.1 - 1.4 9.2 4.9 2.1 8.6 4.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein zf-C2H2 PF00096.26 ORX97709.1 - 3.7e-13 49.1 10.8 8.7e-07 29.1 1.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX97709.1 - 4.1e-11 42.8 18.1 4.2e-08 33.3 3.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX97709.1 - 6.4e-07 29.7 8.8 0.0012 19.5 0.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Ogr_Delta PF04606.12 ORX97709.1 - 0.0015 18.4 3.0 0.0036 17.3 3.0 1.6 1 1 0 1 1 1 1 Ogr/Delta-like zinc finger Zn-C2H2_12 PF18112.1 ORX97709.1 - 0.0049 17.3 2.3 0.32 11.5 0.8 2.4 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain FOXP-CC PF16159.5 ORX97709.1 - 0.02 15.5 0.6 0.38 11.4 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-Di19 PF05605.12 ORX97709.1 - 0.025 14.9 2.8 0.44 10.9 0.4 1.9 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 ORX97709.1 - 0.025 14.3 0.9 0.032 13.9 0.9 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2HC_2 PF13913.6 ORX97709.1 - 0.028 14.3 0.6 0.028 14.3 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FAM150 PF15129.6 ORX97709.1 - 0.097 12.8 2.1 0.41 10.8 2.1 1.9 1 1 0 1 1 1 0 FAM150 family zf-C2H2_jaz PF12171.8 ORX97709.1 - 0.7 10.3 7.5 3.5 8.0 0.2 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding WSD PF15613.6 ORX97710.1 - 5.6e-12 46.0 0.1 5.6e-12 46.0 0.1 3.0 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 ORX97710.1 - 1.4e-05 24.5 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 OEP PF02321.18 ORX97710.1 - 0.15 11.9 5.7 0.049 13.4 1.5 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein DUF465 PF04325.13 ORX97710.1 - 2.3 8.3 6.8 7.2 6.7 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF465) CHZ PF09649.10 ORX97711.1 - 8.3e-06 25.2 0.5 2.5e-05 23.7 0.5 1.8 1 0 0 1 1 1 1 Histone chaperone domain CHZ Usp PF00582.26 ORX97711.1 - 4.1 7.9 6.9 0.7 10.4 0.7 2.2 2 0 0 2 2 2 0 Universal stress protein family Glyco_hydro_16 PF00722.21 ORX97712.1 - 7.3e-37 126.5 5.6 1e-36 126.0 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ORX97712.1 - 0.32 11.5 9.7 0.74 10.3 9.7 1.5 1 0 0 1 1 1 0 Chitin recognition protein GATA PF00320.27 ORX97713.1 - 2e-16 59.3 6.0 3.8e-16 58.4 6.0 1.5 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 ORX97713.1 - 0.55 10.4 2.7 0.45 10.7 0.5 2.0 2 0 0 2 2 2 0 Zinc ribbon domain MBOAT PF03062.19 ORX97714.1 - 8.3e-22 78.0 18.3 8.3e-22 78.0 18.3 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORX97714.1 - 0.00014 22.1 2.9 0.00014 22.1 2.9 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family TauD PF02668.16 ORX97715.1 - 3.5e-56 191.0 0.0 4.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HHH_5 PF14520.6 ORX97716.1 - 1.7e-09 38.1 0.2 3.2e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rad51 PF08423.11 ORX97716.1 - 3.9e-08 32.9 0.0 5.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 AbiEi_4 PF13338.6 ORX97716.1 - 0.03 14.5 0.0 0.086 13.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HHH PF00633.23 ORX97716.1 - 0.092 12.7 1.8 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HhH-GPD PF00730.25 ORX97716.1 - 0.12 12.8 0.1 0.19 12.2 0.1 1.4 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein UCH PF00443.29 ORX97717.1 - 2.5e-38 132.1 0.0 3.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORX97717.1 - 3e-13 49.9 1.9 5.6e-13 49.0 1.9 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORX97717.1 - 1.4e-05 24.8 0.0 6.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Iso_dh PF00180.20 ORX97718.1 - 7.1e-79 265.5 0.0 8.5e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IL31 PF15209.6 ORX97719.1 - 0.086 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Interleukin 31 CheX PF13690.6 ORX97719.1 - 1 9.6 2.8 1.2 9.4 0.3 2.0 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX Thioredoxin PF00085.20 ORX97720.1 - 8.5e-27 93.2 0.2 1e-26 92.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORX97720.1 - 4.6e-05 23.8 0.1 0.0012 19.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORX97720.1 - 7.9e-05 22.9 0.0 0.00075 19.8 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ORX97720.1 - 0.00013 21.7 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ORX97720.1 - 0.00017 21.5 0.0 0.00031 20.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ORX97720.1 - 0.00036 20.6 0.0 0.00065 19.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 ORX97720.1 - 0.0023 17.7 0.1 0.0044 16.7 0.1 1.7 1 1 0 1 1 1 1 Redoxin Pkinase PF00069.25 ORX97721.1 - 2e-66 224.1 0.0 3.5e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97721.1 - 3.7e-39 134.6 0.0 7.7e-39 133.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3552 PF12072.8 ORX97721.1 - 1.2e-06 28.2 16.1 2e-06 27.4 16.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Kinase-like PF14531.6 ORX97721.1 - 0.00025 20.5 0.0 0.00058 19.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.11 ORX97721.1 - 0.00035 20.9 13.9 0.00061 20.1 13.9 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Haspin_kinase PF12330.8 ORX97721.1 - 0.00089 18.3 0.2 0.00089 18.3 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORX97721.1 - 0.0015 18.5 2.0 0.0025 17.8 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family UPF0242 PF06785.11 ORX97721.1 - 0.0046 17.1 11.7 0.0046 17.1 11.7 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Pkinase_fungal PF17667.1 ORX97721.1 - 0.019 13.8 1.6 0.051 12.3 0.0 2.2 2 1 0 2 2 2 0 Fungal protein kinase Thymidylate_kin PF02223.17 ORX97721.1 - 0.056 13.1 2.2 0.1 12.3 0.9 2.1 2 1 0 2 2 2 0 Thymidylate kinase Atg14 PF10186.9 ORX97721.1 - 0.073 12.2 12.6 0.13 11.3 12.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 ORX97721.1 - 0.16 11.5 7.6 0.24 10.9 7.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF390 PF04094.14 ORX97721.1 - 0.26 9.5 6.2 0.37 9.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Lectin_N PF03954.14 ORX97721.1 - 0.42 10.3 4.0 3.4 7.4 4.0 2.3 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 ORX97721.1 - 1.5 8.1 6.2 2.5 7.4 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 ORX97721.1 - 2.1 9.1 11.8 36 5.1 6.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 ORX97721.1 - 2.3 6.7 10.0 0.7 8.4 6.0 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 ORX97721.1 - 4 7.8 17.8 0.3 11.4 12.5 1.9 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 ORX97721.1 - 5.7 6.4 14.3 11 5.5 14.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MerR-DNA-bind PF09278.11 ORX97721.1 - 7.1 7.3 11.1 0.91 10.1 0.6 2.6 1 1 0 2 2 2 0 MerR, DNA binding DUF16 PF01519.16 ORX97721.1 - 8.6 6.9 11.4 0.52 10.8 5.2 2.1 2 1 1 3 3 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 ORX97721.1 - 9.5 5.0 19.0 1.7 7.4 14.9 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Ribosomal_S17e PF00833.18 ORX97722.1 - 1.3e-64 215.6 0.2 1.6e-64 215.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Sof1 PF04158.14 ORX97723.1 - 1.8e-33 114.7 14.9 3.1e-33 113.9 14.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 ORX97723.1 - 1.9e-29 101.3 4.9 0.00022 21.9 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX97723.1 - 1.3e-08 35.0 0.0 0.13 12.6 0.0 4.2 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORX97723.1 - 0.00027 20.9 0.0 2.9 8.0 0.0 4.0 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Ntox21 PF15526.6 ORX97723.1 - 0.12 12.7 1.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Novel toxin 21 RabGAP-TBC PF00566.18 ORX97724.1 - 1.1e-54 185.4 0.3 1.4e-54 185.0 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phospholip_A2_2 PF05826.12 ORX97725.1 - 0.024 14.9 3.7 0.91 9.8 1.2 2.2 1 1 1 2 2 2 0 Phospholipase A2 NAP PF00956.18 ORX97726.1 - 4e-91 304.9 12.7 4e-91 304.9 12.7 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Dynamin_M PF01031.20 ORX97726.1 - 0.02 14.1 0.4 0.031 13.5 0.4 1.3 1 0 0 1 1 1 0 Dynamin central region Cwf_Cwc_15 PF04889.12 ORX97726.1 - 0.3 10.8 16.5 0.011 15.5 9.8 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein P2 PF07194.11 ORX97726.1 - 1.5 8.9 6.2 0.28 11.2 0.9 2.4 2 0 0 2 2 2 0 P2 response regulator binding domain BUD22 PF09073.10 ORX97726.1 - 8.3 5.6 23.2 9.8 5.4 17.0 2.0 1 1 1 2 2 2 0 BUD22 Lactamase_B_4 PF13691.6 ORX97727.1 - 2.4e-20 72.0 0.0 6.5e-20 70.6 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ORX97727.1 - 7.4e-12 45.2 0.5 1.9e-11 43.9 0.5 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORX97727.1 - 0.0076 16.3 0.2 0.015 15.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Caf4 PF11615.8 ORX97727.1 - 0.11 12.5 0.0 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 CCR4-associated factor 4 Ribosomal_L39 PF00832.20 ORX97728.1 - 5.1e-23 80.4 10.8 5.8e-23 80.3 10.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein MOR2-PAG1_N PF14222.6 ORX97729.1 - 7.9e-170 566.4 1.6 7.9e-170 566.4 1.6 2.5 3 0 0 3 3 3 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 ORX97729.1 - 1.1e-68 231.9 0.5 8.9e-68 228.9 0.0 2.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 ORX97729.1 - 8.2e-60 202.6 15.8 2.3e-30 105.1 0.0 4.4 1 1 2 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.6 ORX97729.1 - 0.0057 17.0 2.3 0.3 11.5 0.0 4.4 6 0 0 6 6 6 1 HEAT repeats UME PF08064.13 ORX97729.1 - 0.059 13.3 4.2 3.3 7.7 0.1 4.1 3 0 0 3 3 3 0 UME (NUC010) domain HEAT PF02985.22 ORX97729.1 - 0.13 12.6 1.6 20 5.8 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat RNA_pol_Rpb4 PF03874.16 ORX97729.1 - 0.21 11.9 4.8 3.6 7.9 0.4 3.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 Muted PF14942.6 ORX97730.1 - 7.1e-06 26.4 3.9 8.6e-06 26.2 3.9 1.2 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 ORX97730.1 - 0.00096 18.1 3.6 0.0011 18.0 3.6 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 ORX97730.1 - 0.01 15.5 1.9 0.014 15.0 1.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SKA2 PF16740.5 ORX97730.1 - 0.023 14.4 1.5 0.03 14.1 1.5 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 KxDL PF10241.9 ORX97730.1 - 0.034 14.4 0.6 0.057 13.7 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Prominin PF05478.11 ORX97730.1 - 0.042 11.8 0.7 0.043 11.8 0.7 1.0 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 ORX97730.1 - 0.045 13.8 0.4 0.058 13.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 ORX97730.1 - 0.047 13.8 1.0 0.06 13.5 1.0 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 ORX97730.1 - 0.054 13.5 3.0 1.3 9.0 0.2 2.1 1 1 1 2 2 2 0 Laminin Domain II Tup_N PF08581.10 ORX97730.1 - 0.058 13.7 3.8 0.38 11.1 1.1 2.2 1 1 1 2 2 2 0 Tup N-terminal LIF_OSM PF01291.17 ORX97730.1 - 0.068 13.3 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 LIF / OSM family TMPIT PF07851.13 ORX97730.1 - 0.14 11.4 2.2 0.17 11.1 2.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 ORX97730.1 - 1.1 9.7 4.5 15 6.1 0.4 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) MBOAT PF03062.19 ORX97731.1 - 1e-49 169.8 25.1 1e-49 169.8 25.1 2.2 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DPPIV_N PF00930.21 ORX97732.1 - 7.2e-97 324.3 2.7 9.4e-97 323.9 2.7 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORX97732.1 - 7.8e-42 143.1 0.2 1.2e-41 142.5 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORX97732.1 - 8.4e-05 22.3 0.8 0.018 14.7 0.4 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ORX97732.1 - 0.00012 22.8 0.0 0.0039 17.8 0.0 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.12 ORX97732.1 - 0.0012 18.7 4.7 6.7 6.8 0.1 4.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 ORX97732.1 - 0.019 14.3 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX97732.1 - 0.067 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1295 PF06966.12 ORX97733.1 - 6.4e-43 146.9 6.1 1e-42 146.3 6.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORX97733.1 - 0.00018 21.8 1.1 0.00018 21.8 1.1 2.9 2 2 1 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.16 ORX97733.1 - 0.00024 21.1 2.9 0.00024 21.1 2.9 2.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ORX97733.1 - 0.0038 17.6 0.1 0.0038 17.6 0.1 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ac76 PF05814.11 ORX97733.1 - 0.68 10.0 2.9 1.6 8.7 1.0 2.5 3 0 0 3 3 3 0 Orf76 (Ac76) Flavi_DEAD PF07652.14 ORX97734.1 - 0.043 13.8 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain Mito_carr PF00153.27 ORX97735.1 - 1e-55 185.6 7.0 1.2e-21 76.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Got1 PF04178.12 ORX97736.1 - 6.6e-35 119.9 14.9 9e-35 119.5 14.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AgrB PF04647.15 ORX97736.1 - 0.023 14.0 10.8 0.03 13.6 10.8 1.1 1 0 0 1 1 1 0 Accessory gene regulator B ATP_bind_1 PF03029.17 ORX97737.1 - 4.2e-84 282.1 0.1 5e-84 281.9 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORX97737.1 - 0.00013 21.1 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 ORX97737.1 - 0.00076 19.4 0.0 0.01 15.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 ORX97737.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORX97737.1 - 0.0047 17.0 0.0 0.005 16.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORX97737.1 - 0.0078 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 ORX97737.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 ORX97737.1 - 0.021 14.6 0.0 0.062 13.1 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 ORX97737.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 ORX97737.1 - 0.027 13.9 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 ORX97737.1 - 0.031 14.5 0.0 0.073 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORX97737.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORX97737.1 - 0.042 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 ORX97737.1 - 0.076 12.6 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORX97737.1 - 0.078 13.5 0.2 0.19 12.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ORX97737.1 - 0.093 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORX97737.1 - 0.12 12.8 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORX97737.1 - 0.16 12.3 0.1 0.45 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX97737.1 - 0.16 11.8 0.1 0.49 10.3 0.1 1.8 2 0 0 2 2 2 0 NTPase MMtag PF10159.9 ORX97738.1 - 3.2e-31 107.4 2.9 3.2e-31 107.4 2.9 3.2 3 0 0 3 3 3 1 Multiple myeloma tumor-associated Myb_Cef PF11831.8 ORX97739.1 - 2.7e-59 200.6 1.8 2.7e-59 200.6 1.8 3.8 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 ORX97739.1 - 6.6e-23 80.7 5.3 2e-11 43.9 1.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX97739.1 - 2.3e-20 72.6 7.8 9.6e-14 51.4 3.2 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 ORX97739.1 - 1 9.5 6.4 1.1 9.3 0.1 3.7 4 2 1 5 5 5 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MA3 PF02847.17 ORX97740.1 - 1.7e-28 98.9 1.1 4e-28 97.7 1.1 1.7 1 0 0 1 1 1 1 MA3 domain Thr_synth_N PF14821.6 ORX97740.1 - 0.12 12.6 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus SPX PF03105.19 ORX97740.1 - 1.1 9.2 39.8 0.34 10.8 1.3 2.7 2 1 0 2 2 2 0 SPX domain DNA_pol_phi PF04931.13 ORX97740.1 - 7 4.6 23.7 0.51 8.4 8.8 2.4 2 0 0 2 2 2 0 DNA polymerase phi HECT PF00632.25 ORX97741.1 - 7.7e-86 288.3 0.0 2.9e-85 286.5 0.0 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 ORX97741.1 - 2.8e-15 56.3 3.9 6e-15 55.2 3.9 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Myb_DNA-binding PF00249.31 ORX97743.1 - 3.1e-34 116.9 0.1 1.1e-19 70.3 1.3 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX97743.1 - 3e-24 85.0 0.1 1.9e-18 66.5 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORX97743.1 - 2.4e-05 24.1 0.1 0.0066 16.3 0.1 2.0 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORX97743.1 - 0.0098 16.1 0.0 0.36 11.0 0.0 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Spore_III_AB PF09548.10 ORX97743.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SLIDE PF09111.10 ORX97743.1 - 0.015 15.3 0.0 0.87 9.6 0.0 2.1 1 1 1 2 2 2 0 SLIDE Sigma70_r4_2 PF08281.12 ORX97743.1 - 0.035 13.8 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Myb_DNA-bind_2 PF08914.11 ORX97743.1 - 0.058 13.6 1.1 6 7.1 0.2 3.2 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 ORX97743.1 - 0.27 11.6 5.3 0.33 11.4 0.9 2.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Peptidase_M15_4 PF13539.6 ORX97768.1 - 0.057 13.9 0.1 0.27 11.8 0.1 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AMP-binding PF00501.28 ORX97769.1 - 0 1851.4 1.0 3.9e-95 318.9 0.0 10.0 8 2 1 9 9 9 9 AMP-binding enzyme Condensation PF00668.20 ORX97769.1 - 0 1563.4 24.8 5.6e-62 209.9 0.0 15.1 10 3 4 14 14 14 14 Condensation domain PP-binding PF00550.25 ORX97769.1 - 3.1e-84 277.3 2.2 6.6e-13 48.8 0.0 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORX97769.1 - 3.3e-36 124.1 0.2 7e-05 23.7 0.0 8.1 7 0 0 7 7 7 7 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 ORX97769.1 - 2.8e-26 93.1 0.1 1.3e-25 90.8 0.0 2.3 2 0 0 2 2 1 1 Thioesterase domain TraY PF05509.11 ORX97769.1 - 0.00044 20.2 0.0 1.9 8.6 0.0 2.8 2 0 0 2 2 2 2 TraY domain UFD1 PF03152.14 ORX97769.1 - 0.0032 16.9 0.0 2.9 7.3 0.0 3.1 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 DUF2974 PF11187.8 ORX97769.1 - 0.0042 16.7 0.2 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) PE-PPE PF08237.11 ORX97769.1 - 0.044 13.3 0.2 2.5 7.6 0.0 3.5 3 0 0 3 3 3 0 PE-PPE domain Hydrolase_4 PF12146.8 ORX97769.1 - 0.051 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX97769.1 - 0.053 14.1 0.0 0.21 12.2 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family S_100 PF01023.19 ORX97769.1 - 0.082 12.6 2.6 11 5.8 0.2 2.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Abhydrolase_1 PF00561.20 ORX97769.1 - 0.093 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sec23_BS PF08033.12 ORX97769.1 - 0.17 12.6 0.5 58 4.5 0.0 3.7 3 0 0 3 3 3 0 Sec23/Sec24 beta-sandwich domain CHAP PF05257.16 ORX97770.1 - 2.7e-10 40.7 2.1 4.3e-10 40.0 2.1 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX97771.1 - 2.4e-10 40.9 2.1 3.6e-10 40.3 2.1 1.3 1 0 0 1 1 1 1 CHAP domain KH_1 PF00013.29 ORX97772.1 - 8.4e-49 163.3 10.5 2.3e-18 65.7 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX97772.1 - 1.5e-15 56.8 8.4 3.8e-05 23.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX97772.1 - 3.7e-06 26.7 3.7 0.071 13.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORX97772.1 - 5.5e-05 23.2 6.8 0.1 12.7 0.2 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 ORX97772.1 - 0.015 15.3 0.1 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain zf-AN1 PF01428.16 ORX97773.1 - 4.4e-13 49.2 4.4 4.4e-13 49.2 4.4 1.7 1 1 1 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX97773.1 - 0.0081 16.5 4.7 0.0081 16.5 4.7 1.7 2 0 0 2 2 2 1 Tc5 transposase C-terminal domain CD45 PF12567.8 ORX97773.1 - 0.23 11.4 5.3 2 8.4 0.4 2.5 1 1 1 2 2 2 0 Leukocyte receptor CD45 IBR PF01485.21 ORX97773.1 - 0.25 11.6 10.0 0.52 10.6 9.2 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF35_N PF12172.8 ORX97773.1 - 4.2 7.3 9.9 0.65 9.9 4.9 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-AN1 PF01428.16 ORX97774.1 - 3.9e-13 49.3 5.5 3.9e-13 49.3 5.5 1.7 1 1 1 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX97774.1 - 0.16 12.4 8.1 0.062 13.7 5.7 1.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF35_N PF12172.8 ORX97774.1 - 0.53 10.2 7.6 0.91 9.5 2.6 2.5 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-AN1 PF01428.16 ORX97775.1 - 9e-13 48.2 4.3 9e-13 48.2 4.3 1.8 1 1 1 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORX97775.1 - 0.0026 18.1 4.8 0.0049 17.2 4.8 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain ubiquitin PF00240.23 ORX97776.1 - 2.4e-34 116.9 0.9 3.4e-34 116.4 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX97776.1 - 4.5e-16 58.4 1.0 6.8e-16 57.9 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 ORX97776.1 - 4.5e-11 42.7 3.4 4.5e-11 42.7 3.4 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 ORX97776.1 - 1.8e-05 25.1 0.2 6.8e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORX97776.1 - 0.0041 17.0 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORX97776.1 - 0.005 16.9 0.3 0.011 15.8 0.1 1.8 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORX97776.1 - 0.0056 17.0 0.3 0.011 16.1 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain Transp_Tc5_C PF04236.15 ORX97776.1 - 0.011 16.1 4.4 0.011 16.1 4.4 2.5 2 1 1 3 3 2 0 Tc5 transposase C-terminal domain DUF2407 PF10302.9 ORX97776.1 - 0.018 15.6 0.1 0.023 15.3 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORX97776.1 - 0.026 14.6 1.2 4.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORX97776.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain RGS PF00615.19 ORX97777.1 - 5.5e-18 65.4 3.7 8.9e-18 64.7 3.7 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Baculo_11_kDa PF06143.11 ORX97777.1 - 0.044 13.4 2.1 0.056 13.0 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DALR_1 PF05746.15 ORX97778.1 - 5.3e-12 46.0 0.0 2.2e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain GDP_Man_Dehyd PF16363.5 ORX97779.1 - 1.7e-54 185.4 0.0 2.3e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX97779.1 - 2.9e-48 164.4 0.0 3.6e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX97779.1 - 2e-14 53.5 0.0 1.3e-13 50.8 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORX97779.1 - 2.3e-14 53.1 0.0 1.1e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORX97779.1 - 1.2e-09 37.7 0.0 2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORX97779.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORX97779.1 - 1.1e-05 25.4 0.0 2.7e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 ORX97779.1 - 5.4e-05 22.5 0.1 0.3 10.2 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ORX97779.1 - 0.0063 16.1 0.1 0.34 10.4 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 ORX97779.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Isochorismatase PF00857.20 ORX97779.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Isochorismatase family NAD_binding_10 PF13460.6 ORX97779.1 - 0.025 14.5 0.0 0.071 13.0 0.0 1.8 2 1 0 2 2 2 0 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 ORX97779.1 - 0.046 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 ORX97779.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORX97779.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 ORX97779.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GalKase_gal_bdg PF10509.9 ORX97780.1 - 4.8e-21 74.1 0.1 9.7e-21 73.1 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 ORX97780.1 - 2.2e-13 50.2 1.4 4e-13 49.4 1.4 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX97780.1 - 4.1e-13 49.5 0.0 7.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transferase PF00483.23 ORX97781.1 - 1.3e-52 178.9 0.0 1.9e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORX97781.1 - 2.5e-12 46.0 7.4 9.6e-11 41.0 1.4 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORX97781.1 - 2.1e-10 41.2 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORX97781.1 - 0.0011 18.7 12.9 0.0028 17.4 2.9 3.5 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORX97781.1 - 0.028 12.6 0.2 0.038 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 ORX97781.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4253 PF14062.6 ORX97781.1 - 0.11 12.6 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) CTP_transf_3 PF02348.19 ORX97781.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4536 PF15055.6 ORX97782.1 - 9.6e-07 28.9 3.5 4.5e-06 26.8 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4536) CLASP_N PF12348.8 ORX97783.1 - 3.6e-25 88.9 0.0 5.1e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 ORX97783.1 - 0.039 14.3 0.0 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 ORX97784.1 - 2.1e-12 46.2 3.1 0.99 9.8 0.0 7.5 7 0 0 7 7 7 4 HEAT repeat RTP1_C1 PF10363.9 ORX97784.1 - 1.4e-05 25.2 6.0 0.36 11.0 0.0 5.7 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 ORX97784.1 - 0.00011 21.8 1.9 0.011 15.3 0.0 3.5 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 ORX97784.1 - 0.0019 18.5 0.0 1.4 9.4 0.0 4.4 2 1 1 4 4 4 2 HEAT repeats V-ATPase_H_C PF11698.8 ORX97784.1 - 0.015 15.4 5.1 35 4.6 0.0 5.3 5 0 0 5 5 5 0 V-ATPase subunit H Cohesin_HEAT PF12765.7 ORX97784.1 - 0.11 12.8 0.4 34 4.9 0.1 3.9 3 1 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.7 ORX97784.1 - 1.4 8.8 13.4 0.24 11.3 0.1 4.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Aquarius_N PF16399.5 ORX97785.1 - 1.4e-278 926.3 2.2 1.7e-278 926.0 2.2 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 ORX97785.1 - 2.3e-29 103.0 0.0 2.8e-28 99.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 ORX97785.1 - 1.5e-27 96.6 0.0 3.6e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORX97785.1 - 3.2e-10 40.5 0.0 2.5e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX97785.1 - 3e-08 33.6 0.0 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 ORX97785.1 - 1.8e-06 28.1 0.0 4.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORX97785.1 - 1.7e-05 24.5 0.0 8.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 ORX97785.1 - 0.00055 19.7 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 ORX97785.1 - 0.0028 18.1 0.0 0.008 16.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 ORX97785.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 ORX97785.1 - 0.0085 15.9 0.0 0.51 10.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 ORX97785.1 - 0.02 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 ORX97785.1 - 0.041 13.1 0.3 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 ORX97785.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 ORX97785.1 - 0.046 14.1 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORX97785.1 - 0.084 13.2 0.0 0.44 10.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORX97785.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RrnaAD PF00398.20 ORX97786.1 - 0.0015 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 ORX97786.1 - 0.0064 16.3 0.0 0.009 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-CCHC PF00098.23 ORX97786.1 - 0.025 14.7 5.9 0.065 13.3 5.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_25 PF13649.6 ORX97786.1 - 0.027 15.2 0.0 0.072 13.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Carb_kinase PF01256.17 ORX97786.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase CHAP PF05257.16 ORX97787.1 - 4.5e-10 40.0 3.9 7.5e-10 39.3 3.9 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX97788.1 - 4.4e-10 40.0 3.9 7.5e-10 39.3 3.9 1.4 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX97789.1 - 4.4e-10 40.0 3.9 7.5e-10 39.3 3.9 1.4 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX97790.1 - 3.8e-10 40.2 3.5 6.5e-10 39.5 3.5 1.4 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX97791.1 - 4.5e-10 40.0 3.9 7.5e-10 39.3 3.9 1.3 1 0 0 1 1 1 1 CHAP domain Thiol_cytolysin PF01289.19 ORX97792.1 - 4.8e-33 114.5 0.0 5.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Thiol-activated cytolysin E1-E2_ATPase PF00122.20 ORX97818.1 - 1.1e-40 139.0 2.4 3.2e-40 137.6 0.3 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX97818.1 - 1.5e-33 116.1 6.8 1.5e-33 116.1 6.8 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORX97818.1 - 1.3e-21 77.9 0.0 3.5e-10 40.5 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORX97818.1 - 3.7e-19 68.6 0.0 9.1e-19 67.3 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX97818.1 - 2.6e-08 33.4 0.1 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX97818.1 - 8.8e-05 22.4 0.2 0.00031 20.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX97818.1 - 0.0016 18.8 0.0 0.019 15.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 ORX97819.1 - 1.3e-06 28.6 8.1 1.3e-06 28.6 8.1 2.4 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 ORX97819.1 - 0.00023 21.3 4.8 0.00061 19.9 4.8 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 ORX97819.1 - 0.00028 21.1 5.7 0.0011 19.3 5.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORX97819.1 - 0.0011 19.0 2.2 0.0027 17.7 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 ORX97819.1 - 0.0011 18.8 8.0 0.0037 17.1 8.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BACK PF07707.15 ORX97819.1 - 0.031 14.4 0.5 0.13 12.4 0.5 2.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch zf-RING-like PF08746.11 ORX97819.1 - 0.037 14.3 7.6 0.087 13.1 7.6 1.7 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 ORX97819.1 - 0.042 14.0 6.8 0.11 12.6 6.8 1.8 1 0 0 1 1 1 0 RING-variant domain ZapA PF05164.13 ORX97819.1 - 0.15 12.5 0.2 0.43 11.0 0.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapA PHD PF00628.29 ORX97819.1 - 0.52 10.3 5.6 1.1 9.2 5.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 ORX97819.1 - 2.7 7.9 8.5 2.3 8.2 5.3 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Nbl1_Borealin_N PF10444.9 ORX97820.1 - 1.3e-08 34.4 0.2 2.1e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 Nbl1 / Borealin N terminal Endostatin PF06482.11 ORX97820.1 - 0.079 12.4 2.5 0.098 12.1 2.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF1075 PF06388.11 ORX97820.1 - 0.22 11.6 1.9 0.33 11.0 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1075) Gon7 PF08738.10 ORX97820.1 - 3.3 7.8 7.6 0.47 10.6 0.7 2.3 1 1 1 2 2 2 0 Gon7 family Vps5 PF09325.10 ORX97821.1 - 5.7e-71 238.8 17.6 8.1e-71 238.3 17.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORX97821.1 - 9.7e-28 96.4 0.6 3.6e-25 88.2 0.0 2.7 2 1 0 2 2 2 2 PX domain BAR PF03114.18 ORX97821.1 - 0.063 12.9 16.1 0.14 11.8 16.1 1.5 1 1 0 1 1 1 0 BAR domain Atg14 PF10186.9 ORX97821.1 - 1.5 7.8 16.5 1.1 8.3 14.5 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PfkB PF00294.24 ORX97822.1 - 7e-21 74.8 0.0 1.5e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DALR_1 PF05746.15 ORX97823.1 - 0.63 10.2 2.4 5.5 7.2 0.1 2.8 2 0 0 2 2 2 0 DALR anticodon binding domain Kinesin PF00225.23 ORX97824.1 - 1.4e-100 336.5 1.0 2.1e-100 335.9 1.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORX97824.1 - 3.5e-26 91.9 0.1 8.7e-26 90.6 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 ORX97824.1 - 1.2e-05 25.5 0.1 3.8e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif TPR_2 PF07719.17 ORX97824.1 - 0.00021 21.1 0.0 0.00056 19.8 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORX97824.1 - 0.00048 19.8 0.1 0.00097 18.9 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORX97824.1 - 0.0068 16.7 0.1 0.018 15.3 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Importin_rep_6 PF18829.1 ORX97824.1 - 0.022 14.9 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 Importin repeat 6 HHH PF00633.23 ORX97824.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_8 PF13181.6 ORX97824.1 - 0.071 13.4 0.5 0.19 12.0 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3701 PF12482.8 ORX97824.1 - 0.087 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage integrase protein TPR_14 PF13428.6 ORX97824.1 - 0.12 13.3 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat COPI_C PF06957.11 ORX97825.1 - 7.6e-136 453.0 0.0 1e-135 452.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 ORX97825.1 - 1.1e-116 390.5 1.2 3.8e-107 359.1 1.1 2.5 1 1 1 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 ORX97825.1 - 2.5e-47 157.9 11.9 2.3e-08 34.6 0.4 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX97825.1 - 3.3e-13 49.7 0.1 0.00027 21.2 0.0 5.7 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX97825.1 - 0.16 10.6 8.1 0.65 8.6 0.0 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 SRA1 PF07304.11 ORX97826.1 - 1.9e-12 47.2 0.0 2.3e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 ORX97826.1 - 1e-07 32.1 0.2 1.9e-05 24.8 0.2 2.2 1 1 1 2 2 2 2 Prp18 domain DUF1400 PF07176.11 ORX97826.1 - 0.065 13.5 0.3 0.098 12.9 0.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Tetraspanin PF00335.20 ORX97827.1 - 2e-10 40.8 10.0 2.8e-10 40.3 10.0 1.3 1 0 0 1 1 1 1 Tetraspanin family MitoNEET_N PF10660.9 ORX97827.1 - 0.085 12.9 0.6 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus zf-C3H1 PF10650.9 ORX97828.1 - 7.3e-11 41.6 0.7 1.6e-10 40.5 0.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain Laminin_I PF06008.14 ORX97828.1 - 0.073 12.8 9.7 0.04 13.6 4.0 2.4 2 0 0 2 2 2 0 Laminin Domain I PIN_2 PF10130.9 ORX97828.1 - 0.19 11.9 1.1 0.72 10.1 1.1 2.0 1 0 0 1 1 1 0 PIN domain Snapin_Pallidin PF14712.6 ORX97828.1 - 0.6 10.6 12.6 4.5 7.7 6.1 3.1 2 1 1 3 3 3 0 Snapin/Pallidin UPF0242 PF06785.11 ORX97828.1 - 2.6 8.1 12.5 2.2 8.3 8.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ORX97828.1 - 4.1 7.9 16.3 3.8 8.0 8.0 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 ORX97828.1 - 7 5.4 17.7 0.64 8.9 3.5 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein CAF1 PF04857.20 ORX97829.1 - 4.8e-67 226.4 1.2 7.7e-35 120.6 0.4 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 ORX97829.1 - 0.003 17.3 0.1 0.37 10.5 0.1 2.5 2 0 0 2 2 2 1 3'-5' exonuclease zf_CCCH_4 PF18345.1 ORX97829.1 - 0.027 14.5 0.9 0.046 13.8 0.9 1.4 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 ORX97829.1 - 0.028 15.1 0.2 0.059 14.1 0.2 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH PF00642.24 ORX97829.1 - 0.046 13.6 2.0 0.083 12.8 2.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDH-cyt PF16010.5 ORX97829.1 - 0.2 11.3 1.6 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome domain of cellobiose dehydrogenase tRNA-synt_2 PF00152.20 ORX97830.1 - 1.2e-100 336.7 0.0 1.5e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORX97830.1 - 3.2e-07 30.2 0.0 5.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORX97830.1 - 0.0012 18.4 0.1 0.0096 15.4 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) GAD PF02938.14 ORX97830.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GAD domain FAD-oxidase_C PF02913.19 ORX97831.1 - 4.8e-63 213.1 0.0 6.5e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORX97831.1 - 2.9e-35 121.0 0.4 6e-35 120.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyrophosphatase PF00719.19 ORX97832.1 - 2.9e-56 189.7 0.2 4.8e-56 189.0 0.2 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase RANK_CRD_2 PF18278.1 ORX97832.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DAO PF01266.24 ORX97833.1 - 1.8e-50 172.5 0.1 2.5e-50 172.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ORX97833.1 - 2.9e-47 159.6 0.3 6.3e-47 158.6 0.3 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ORX97833.1 - 2.6e-10 40.0 5.2 6e-09 35.5 5.2 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORX97833.1 - 2.5e-08 33.7 0.7 3.4e-07 30.0 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ORX97833.1 - 3.9e-05 22.9 0.1 0.0021 17.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORX97833.1 - 5.6e-05 22.5 0.2 0.00017 20.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX97833.1 - 0.00073 19.7 0.2 0.0028 17.9 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORX97833.1 - 0.00082 18.7 0.4 0.0047 16.2 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORX97833.1 - 0.0064 15.2 0.2 0.0099 14.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORX97833.1 - 0.042 13.1 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORX97833.1 - 0.046 12.9 1.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ORX97833.1 - 0.054 14.1 0.1 0.15 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BCDHK_Adom3 PF10436.9 ORX97834.1 - 2.2e-24 86.2 0.2 3.4e-24 85.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORX97834.1 - 7.7e-10 39.3 0.0 1.4e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMAP PF06540.11 ORX97834.1 - 0.034 14.2 0.0 5.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Galanin message associated peptide (GMAP) ATP-synt_ab PF00006.25 ORX97835.1 - 1.7e-68 230.5 0.0 2.5e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX97835.1 - 6.7e-12 45.8 0.6 1.3e-11 44.8 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 ORX97835.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TNFR_16_TM PF18422.1 ORX97836.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain PP2C PF00481.21 ORX97838.1 - 5.6e-75 252.3 0.0 6.7e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PCI PF01399.27 ORX97839.1 - 3.5e-17 62.8 0.0 7e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain DCB PF16213.5 ORX97839.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 TPR_2 PF07719.17 ORX97839.1 - 0.12 12.6 5.7 0.42 10.8 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LUC7 PF03194.15 ORX97840.1 - 1.6e-77 260.6 8.0 1.6e-77 260.6 8.0 1.4 2 0 0 2 2 2 1 LUC7 N_terminus Ferritin-like PF12902.7 ORX97840.1 - 0.018 14.9 0.4 0.028 14.3 0.4 1.3 1 0 0 1 1 1 0 Ferritin-like Ran-binding PF05508.11 ORX97840.1 - 0.034 13.1 1.6 0.08 11.9 0.3 1.9 2 0 0 2 2 2 0 RanGTP-binding protein FlxA PF14282.6 ORX97840.1 - 0.11 12.4 12.1 1.7 8.7 3.8 2.4 1 1 1 2 2 2 0 FlxA-like protein KMP11 PF03037.16 ORX97840.1 - 0.14 12.9 3.6 0.16 12.8 0.9 2.4 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 FUSC PF04632.12 ORX97840.1 - 0.22 10.0 0.1 0.31 9.5 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Hsk3 PF08227.11 ORX97840.1 - 1.2 9.6 4.1 2.4 8.6 4.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like ABC_tran_CTD PF16326.5 ORX97840.1 - 1.5 9.1 13.2 0.37 11.1 8.0 2.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 ORX97840.1 - 9.9 6.0 10.2 4.2 7.2 2.3 2.8 1 1 1 2 2 2 0 Septum formation initiator CBFD_NFYB_HMF PF00808.23 ORX97841.1 - 8.3e-19 67.6 0.0 1.9e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORX97841.1 - 2.9e-05 24.4 0.1 0.00017 22.0 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORX97841.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold GIY-YIG PF01541.24 ORX97842.1 - 4e-15 55.8 0.0 6.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 ORX97842.1 - 8e-06 26.0 4.8 1.6e-05 25.0 4.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 ORX97842.1 - 0.0035 17.0 2.9 0.0099 15.6 2.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORX97842.1 - 0.016 15.6 10.0 0.06 13.7 10.0 2.0 1 1 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 ORX97842.1 - 0.022 15.0 3.1 0.022 15.0 3.1 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain PikAIV_N PF18605.1 ORX97842.1 - 0.28 10.8 0.8 18 5.0 0.2 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Tmpp129 PF10272.9 ORX97842.1 - 0.53 9.5 6.5 0.45 9.8 4.2 1.8 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-C3HC4_2 PF13923.6 ORX97842.1 - 1.3 9.0 10.3 1.6 8.6 5.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX97842.1 - 1.7 8.7 10.2 7.4 6.6 10.2 2.1 1 1 0 1 1 1 0 zinc-RING finger domain DUF3746 PF12562.8 ORX97842.1 - 3.4 7.7 5.9 8 6.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3746) zf-C3HC4 PF00097.25 ORX97842.1 - 5.5 6.9 9.6 2.6 8.0 5.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Phosphodiest PF01663.22 ORX97843.1 - 1.1e-90 304.8 0.7 1.3e-90 304.6 0.7 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORX97843.1 - 0.022 14.2 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Sulfatase HA2 PF04408.23 ORX97844.1 - 5e-18 65.4 0.0 1.3e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORX97844.1 - 4.3e-15 56.0 0.0 1.6e-14 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORX97844.1 - 3.4e-14 52.9 0.0 1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 ORX97844.1 - 6.4e-12 45.8 3.4 6.5e-12 45.8 1.1 2.3 2 0 0 2 2 2 1 RWD domain DEAD PF00270.29 ORX97844.1 - 4.1e-08 33.2 2.1 2e-06 27.7 2.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2742 PF10888.8 ORX97844.1 - 0.0002 21.6 0.7 2.6e+02 1.9 0.0 6.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2742) UBA PF00627.31 ORX97844.1 - 0.00024 20.9 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain NTP_transf_9 PF04248.12 ORX97844.1 - 0.00063 19.6 72.0 7.9 6.5 0.2 17.5 7 6 16 23 23 23 5 Domain of unknown function (DUF427) dsRBD2 PF17842.1 ORX97844.1 - 0.0035 17.6 0.0 0.016 15.5 0.0 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 YolD PF08863.10 ORX97844.1 - 0.0088 16.1 0.8 3.4 7.8 0.1 5.5 8 0 0 8 8 8 1 YolD-like protein AAA_30 PF13604.6 ORX97844.1 - 0.0089 15.8 0.0 0.037 13.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORX97844.1 - 0.025 14.6 0.1 0.22 11.5 0.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 ORX97844.1 - 0.032 14.7 0.1 0.15 12.6 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 ORX97844.1 - 0.062 13.6 2.7 0.57 10.5 2.7 2.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORX97844.1 - 0.063 13.3 1.0 0.43 10.6 0.2 2.7 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 ORX97844.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DsbG_N PF18257.1 ORX97844.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Disulfide isomerase DsbG N-terminal AAA_23 PF13476.6 ORX97844.1 - 0.18 12.3 3.5 0.11 13.0 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORX97844.1 - 1.1 9.6 2.6 1.4 9.3 0.5 2.2 2 1 0 2 2 2 0 AAA domain Toxin_30 PF08117.11 ORX97844.1 - 3 8.2 17.0 2e+02 2.3 0.1 6.5 6 0 0 6 6 6 0 Ptu family ACC_central PF08326.12 ORX97875.1 - 3.4e-243 809.1 2.5 4.7e-243 808.7 2.5 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORX97875.1 - 7.8e-176 585.5 0.0 1.2e-175 584.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORX97875.1 - 1.6e-52 178.1 0.0 4e-52 176.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORX97875.1 - 9.3e-29 100.2 0.1 1.9e-28 99.2 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORX97875.1 - 1e-20 73.8 0.0 8.7e-20 70.8 0.0 2.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORX97875.1 - 1e-16 60.5 0.0 3e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 ORX97875.1 - 0.00012 22.2 0.0 0.00056 20.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORX97875.1 - 0.014 15.0 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORX97875.1 - 0.022 14.3 0.1 0.068 12.7 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORX97875.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon SWIRM PF04433.17 ORX97876.1 - 2.7e-11 43.7 0.0 1.4e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain CS PF04969.16 ORX97877.1 - 1.3e-20 74.2 0.5 2.5e-20 73.3 0.5 1.5 1 0 0 1 1 1 1 CS domain Ca_chan_IQ PF08763.11 ORX97877.1 - 0.16 12.2 2.4 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain DUF4355 PF14265.6 ORX97877.1 - 1 9.6 8.8 0.094 13.0 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) HMG_box PF00505.19 ORX97877.1 - 1.4 9.4 9.5 4.9 7.6 0.0 2.9 3 0 0 3 3 3 0 HMG (high mobility group) box Hexokinase_2 PF03727.16 ORX97878.1 - 3e-69 233.1 0.0 3.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORX97878.1 - 1.4e-62 211.2 0.0 2e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase BTG PF07742.12 ORX97879.1 - 2.5e-19 69.2 0.0 2.9e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 BTG family RGS PF00615.19 ORX97880.1 - 7.3e-18 65.0 1.6 1.3e-17 64.1 1.6 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX97880.1 - 5.1e-07 29.7 19.4 3.6e-06 26.9 19.4 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RecX PF02631.16 ORX97880.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 RecX family Peptidase_M28 PF04389.17 ORX97881.1 - 5e-42 143.8 0.0 7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX97881.1 - 1.8e-10 40.7 0.1 4.4e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX97881.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORX97881.1 - 0.072 12.1 0.0 0.43 9.5 0.0 2.2 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 ORX97882.1 - 1.1e-34 119.9 0.0 1.6e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX97882.1 - 7.3e-10 38.7 0.1 2e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX97882.1 - 0.00026 20.8 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORX97882.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Metallophos PF00149.28 ORX97883.1 - 3.2e-33 116.0 0.1 4e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DLIC PF05783.11 ORX97884.1 - 3.1e-73 247.2 12.7 6.4e-65 219.8 0.1 4.6 2 2 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 ORX97884.1 - 0.00069 19.8 0.1 0.0069 16.6 0.1 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORX97884.1 - 0.0017 18.8 0.0 0.0077 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 ORX97884.1 - 0.0047 16.4 0.0 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein GTP_EFTU PF00009.27 ORX97884.1 - 0.0088 15.6 0.0 0.48 9.9 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ORX97884.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 ORX97884.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 ORX97884.1 - 0.15 11.9 0.1 17 5.2 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase TIP49 PF06068.13 ORX97884.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain KilA-N PF04383.13 ORX97886.1 - 0.00078 19.3 0.0 0.0068 16.2 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Asparaginase PF00710.20 ORX97887.1 - 5.2e-28 97.9 0.0 7.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORX97887.1 - 8e-11 42.2 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain zf-H2C2_2 PF13465.6 ORX97888.1 - 2.2e-21 75.2 31.4 2.6e-08 33.9 2.8 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORX97888.1 - 2.6e-20 71.6 30.3 3.9e-06 27.0 1.0 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX97888.1 - 2.6e-13 49.5 27.3 0.0032 18.2 0.6 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 ORX97888.1 - 5.1e-07 29.9 12.9 0.73 10.3 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX97888.1 - 8.2e-06 26.0 9.5 2.3 8.6 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORX97888.1 - 1.1e-05 25.9 11.5 0.034 14.8 0.4 3.8 1 1 3 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX97888.1 - 0.0073 16.6 10.4 0.43 10.9 0.4 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-LYAR PF08790.11 ORX97888.1 - 0.013 15.4 11.0 1.3 8.9 0.1 4.6 4 1 0 4 4 4 0 LYAR-type C2HC zinc finger zf-TRAF PF02176.18 ORX97888.1 - 0.016 15.9 10.6 0.039 14.6 1.9 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.12 ORX97888.1 - 0.05 13.6 10.6 6.4 6.9 0.0 4.0 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 ORX97888.1 - 0.096 12.5 11.2 0.59 9.9 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type HNH PF01844.23 ORX97888.1 - 3.3 7.9 9.1 3.5 7.9 0.2 3.4 3 1 1 4 4 4 0 HNH endonuclease ACC_central PF08326.12 ORX97892.1 - 2.6e-228 759.9 2.4 3.3e-228 759.6 2.4 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORX97892.1 - 4.5e-170 566.5 0.0 5.9e-170 566.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORX97892.1 - 2.6e-52 177.4 0.1 3.8e-51 173.6 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORX97892.1 - 1.3e-29 102.9 0.0 2.7e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORX97892.1 - 3.2e-20 72.2 0.0 1.3e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORX97892.1 - 4.2e-14 52.1 0.0 1.4e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORX97892.1 - 4.5e-06 26.3 0.3 0.00012 21.7 0.1 3.1 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ORX97892.1 - 0.0002 21.4 0.0 0.00061 19.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 ORX97892.1 - 0.011 15.3 0.2 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 ATP-grasp domain DER1 PF04511.15 ORX97893.1 - 4.3e-42 144.2 15.6 5.2e-42 143.9 15.6 1.1 1 0 0 1 1 1 1 Der1-like family DUF3593 PF12159.8 ORX97893.1 - 6.2 6.9 11.8 9 6.4 5.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3593) SUI1 PF01253.22 ORX97895.1 - 1.9e-27 95.6 1.2 2.4e-27 95.2 1.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 TPR_1 PF00515.28 ORX97896.1 - 7.3e-15 54.1 2.9 0.00024 20.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORX97896.1 - 8e-09 35.0 1.2 0.0066 16.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 ORX97896.1 - 9e-06 25.9 0.0 3.7e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.6 ORX97896.1 - 0.00025 20.7 0.1 0.055 13.2 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 ORX97896.1 - 0.0003 21.4 0.1 0.17 12.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX97896.1 - 0.00087 19.5 0.6 2.1 8.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORX97896.1 - 0.0011 19.2 0.2 0.024 15.0 0.0 2.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX97896.1 - 0.0015 18.6 0.2 3 8.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORX97896.1 - 0.0035 17.8 0.1 0.095 13.2 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX97896.1 - 0.016 15.8 1.5 3 8.7 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX97896.1 - 0.034 14.2 0.1 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORX97896.1 - 0.3 11.0 1.2 24 5.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UDG PF03167.19 ORX97897.1 - 8.9e-24 84.2 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cation_efflux PF01545.21 ORX97898.1 - 5.3e-23 81.8 13.2 6.5e-23 81.5 13.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORX97898.1 - 1.2e-12 47.7 0.1 2e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter YAF2_RYBP PF17219.3 ORX97910.1 - 0.034 13.7 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif AMP-binding PF00501.28 ORX97912.1 - 5.9e-287 950.9 0.0 3.5e-100 335.6 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 ORX97912.1 - 7.4e-169 562.2 0.0 6.1e-99 331.7 0.0 3.9 3 1 0 3 3 3 3 Condensation domain AMP-binding_C PF13193.6 ORX97912.1 - 6.1e-38 129.7 4.5 1.4e-12 48.4 0.4 3.7 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORX97912.1 - 1e-34 118.7 3.3 5.3e-12 45.9 0.1 4.6 4 0 0 4 4 4 3 Phosphopantetheine attachment site Thioesterase PF00975.20 ORX97912.1 - 3e-19 70.1 0.0 7.4e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 ORX97912.1 - 0.028 15.0 2.9 0.18 12.4 0.0 3.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family HEAT PF02985.22 ORX97912.1 - 0.066 13.5 0.2 32 5.2 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Xan_ur_permease PF00860.20 ORX97913.1 - 6e-63 212.9 36.1 1.4e-61 208.4 36.1 2.1 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 ORX97913.1 - 1.6 9.2 20.0 1.8 9.0 5.6 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Torus PF16131.5 ORX97914.1 - 1e-29 103.4 1.2 1e-29 103.4 1.2 3.5 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 ORX97914.1 - 2.5e-05 24.0 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX97914.1 - 0.0003 20.7 0.2 0.00065 19.7 0.2 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 ORX97914.1 - 0.029 14.4 6.3 0.074 13.1 6.3 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 ORX97914.1 - 2.2 8.2 5.4 4.3 7.3 5.4 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger AAA PF00004.29 ORX97915.1 - 3.3e-96 318.8 0.0 6.3e-48 162.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX97915.1 - 8.2e-22 76.8 0.2 1.9e-10 40.4 0.1 3.2 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 ORX97915.1 - 1.6e-16 60.4 0.1 9.3e-09 35.2 0.0 3.4 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX97915.1 - 6.2e-13 49.2 0.0 1.1e-05 25.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORX97915.1 - 2.4e-12 47.5 2.1 0.0003 21.2 0.1 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 ORX97915.1 - 3.3e-12 46.6 0.3 1.2e-05 25.4 0.1 4.4 4 2 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORX97915.1 - 2.9e-10 40.5 0.0 0.00035 20.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORX97915.1 - 5.6e-10 38.9 0.4 0.00036 19.8 0.1 3.2 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 ORX97915.1 - 6.2e-10 39.5 2.4 0.015 15.6 0.1 4.5 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 ORX97915.1 - 8.8e-09 35.7 0.0 0.0071 16.7 0.0 3.5 3 1 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 ORX97915.1 - 1e-08 35.8 0.0 0.0012 19.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 ORX97915.1 - 9.5e-08 31.8 3.0 0.81 9.2 0.0 4.4 3 1 1 4 4 4 2 AAA domain AAA_14 PF13173.6 ORX97915.1 - 2.3e-07 30.9 0.0 0.033 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ORX97915.1 - 2.6e-07 30.5 0.1 0.026 14.2 0.0 3.0 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORX97915.1 - 6.7e-07 28.9 0.2 0.045 13.1 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ORX97915.1 - 7e-07 29.6 0.0 0.048 13.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 ORX97915.1 - 7.9e-07 29.7 0.0 0.044 14.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 ORX97915.1 - 2.9e-06 26.7 0.0 0.055 12.7 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 ORX97915.1 - 4.6e-06 26.7 1.0 0.19 11.6 0.0 4.0 3 1 1 4 4 4 2 NACHT domain TsaE PF02367.17 ORX97915.1 - 7.7e-06 25.9 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 ORX97915.1 - 1.4e-05 25.0 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORX97915.1 - 1.4e-05 24.6 0.4 1.4 8.2 0.0 3.3 2 1 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 ORX97915.1 - 1.5e-05 24.8 0.0 0.25 11.0 0.0 3.6 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 ORX97915.1 - 2.2e-05 24.0 0.0 0.31 10.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 ORX97915.1 - 3.6e-05 24.2 0.1 0.17 12.3 0.2 3.3 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.10 ORX97915.1 - 7.4e-05 22.7 0.1 0.82 9.7 0.0 3.0 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Rad17 PF03215.15 ORX97915.1 - 0.00012 22.1 0.0 0.8 9.6 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain DUF815 PF05673.13 ORX97915.1 - 0.00013 21.2 0.0 0.0049 16.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORX97915.1 - 0.0003 20.1 0.0 0.86 8.7 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain Viral_helicase1 PF01443.18 ORX97915.1 - 0.00053 19.8 0.0 0.9 9.2 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 ORX97915.1 - 0.00058 20.0 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 ORX97915.1 - 0.00087 19.4 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 ORX97915.1 - 0.00095 18.3 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 ORX97915.1 - 0.0011 18.7 0.0 0.69 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORX97915.1 - 0.0019 18.2 0.1 2 8.3 0.0 3.4 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea PhoH PF02562.16 ORX97915.1 - 0.0028 17.1 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AFG1_ATPase PF03969.16 ORX97915.1 - 0.0064 15.4 0.0 2.3 7.0 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase AAA_11 PF13086.6 ORX97915.1 - 0.0068 16.2 5.6 0.76 9.5 0.0 3.2 3 1 0 3 3 3 2 AAA domain SKI PF01202.22 ORX97915.1 - 0.01 16.0 0.2 8.6 6.5 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase PduV-EutP PF10662.9 ORX97915.1 - 0.013 15.2 0.0 10 5.8 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 ORX97915.1 - 0.021 14.1 0.1 4.4 6.4 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 ORX97915.1 - 0.022 14.6 0.0 0.74 9.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.10 ORX97915.1 - 0.026 14.0 0.0 20 4.6 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 ORX97915.1 - 0.042 13.8 0.0 9 6.2 0.0 3.1 2 0 0 2 2 2 0 NTPase Bac_DnaA PF00308.18 ORX97915.1 - 0.042 13.7 0.0 4.5 7.0 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein Hydin_ADK PF17213.3 ORX97915.1 - 0.042 14.1 4.1 1 9.6 0.0 3.8 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 ORX97915.1 - 0.1 11.7 0.0 4.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 ORX97915.1 - 0.15 12.4 1.6 26 5.1 0.3 3.0 2 1 0 2 2 2 0 AAA domain YchF-GTPase_C PF06071.13 ORX97916.1 - 7.1e-34 115.9 2.8 7.4e-34 115.8 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORX97916.1 - 5e-21 74.9 0.0 2.3e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX97916.1 - 2.6e-07 30.3 0.0 4.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TPT PF03151.16 ORX97917.1 - 2.3e-07 30.5 1.7 2.3e-07 30.5 1.7 2.1 1 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 ORX97917.1 - 2.5e-07 30.9 25.7 1.2e-06 28.8 8.3 4.0 3 1 1 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORX97917.1 - 1.3e-05 24.5 2.0 9.1e-05 21.8 2.5 1.9 1 1 1 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 ORX97917.1 - 6.8e-05 22.2 2.8 6.8e-05 22.2 2.8 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 ORX97917.1 - 0.00061 19.1 0.3 0.00061 19.1 0.3 1.8 2 0 0 2 2 2 1 UAA transporter family CRT-like PF08627.10 ORX97917.1 - 0.00063 18.8 1.5 0.00063 18.8 1.5 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like NAD_binding_2 PF03446.15 ORX97919.1 - 8.3e-22 78.1 0.0 1.2e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ORX97919.1 - 8.8e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORX97919.1 - 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ORX97919.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ORX97919.1 - 0.041 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX97919.1 - 0.081 12.9 0.1 0.4 10.6 0.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DpaA_N PF16924.5 ORX97919.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain GLE1 PF07817.13 ORX97920.1 - 1.8e-82 276.3 0.1 1.8e-82 276.3 0.1 1.9 2 0 0 2 2 2 1 GLE1-like protein DUF5401 PF17380.2 ORX97920.1 - 0.0046 15.1 36.9 0.0063 14.7 36.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5401) PI31_Prot_N PF11566.8 ORX97921.1 - 8.4e-27 94.0 0.0 1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal Glyco_hydro_9 PF00759.19 ORX97922.1 - 5.8e-97 325.7 16.1 7.3e-97 325.4 16.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 THDPS_N PF14790.6 ORX97922.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Tetraspanin PF00335.20 ORX97923.1 - 1.5e-09 37.9 1.5 2.4e-09 37.3 1.5 1.3 1 0 0 1 1 1 1 Tetraspanin family NfrA_C PF13283.6 ORX97923.1 - 0.091 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Tmemb_9 PF05434.11 ORX97923.1 - 4.2 7.3 5.6 20 5.0 0.2 2.1 1 1 1 2 2 2 0 TMEM9 Arrestin_C PF02752.22 ORX97924.1 - 5.9e-10 39.7 0.3 4.2e-09 37.0 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX97924.1 - 0.0002 21.4 0.0 0.0084 16.2 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pho88 PF10032.9 ORX97925.1 - 5e-57 192.1 0.0 5.7e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DEAD PF00270.29 ORX97927.1 - 1.9e-41 141.8 0.2 3.7e-41 140.8 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX97927.1 - 3.6e-31 107.8 2.1 1.2e-27 96.5 0.1 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORX97927.1 - 2.5e-08 34.1 0.1 7.4e-08 32.6 0.0 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 ORX97927.1 - 0.0023 18.1 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Helicase C-terminal domain AAA_22 PF13401.6 ORX97927.1 - 0.0033 17.7 0.0 0.022 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain Cdh1_DBD_1 PF18196.1 ORX97927.1 - 0.096 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 PAPS_reduct PF01507.19 ORX97927.1 - 0.12 12.5 0.3 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family TatD_DNase PF01026.21 ORX97928.1 - 1.1e-56 192.1 0.0 1.3e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase MGAT2 PF05060.14 ORX97928.1 - 0.054 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) E1-E2_ATPase PF00122.20 ORX97929.1 - 5.6e-47 159.6 1.0 5.6e-47 159.6 1.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX97929.1 - 1.1e-32 113.2 1.3 1.1e-32 113.2 1.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX97929.1 - 1.1e-21 76.8 0.0 1.9e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX97929.1 - 3.9e-18 64.9 0.0 8.4e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 ORX97929.1 - 3.1e-17 63.6 0.0 1.1e-15 58.5 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORX97929.1 - 0.0012 18.7 1.4 0.0037 17.0 1.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ORX97930.1 - 2e-53 181.4 0.1 2.2e-38 132.1 0.2 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX97930.1 - 2.8e-29 102.2 0.0 2.1e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORX97930.1 - 2.1e-05 24.0 0.0 0.037 13.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORX97930.1 - 0.0076 15.1 0.4 0.019 13.8 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORX97930.1 - 0.03 14.0 0.1 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORX97930.1 - 0.054 13.4 1.0 1.6 8.6 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family XPA_C PF05181.12 ORX97931.1 - 6.6e-25 86.8 2.5 6.7e-25 86.8 0.4 2.1 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 ORX97931.1 - 1.3e-07 31.5 0.8 1.3e-07 31.5 0.8 2.0 2 0 0 2 2 2 1 XPA protein N-terminal DZR PF12773.7 ORX97931.1 - 0.013 15.5 0.6 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 ORX97931.1 - 0.069 12.8 4.2 2.9 7.7 0.1 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit IMP2_N PF18590.1 ORX97931.1 - 0.18 12.4 0.6 0.38 11.3 0.0 1.8 2 0 0 2 2 1 0 Immune Mapped Protein 2 (IMP2) N-terminal domain TF_Zn_Ribbon PF08271.12 ORX97931.1 - 0.27 10.8 8.9 1.1 8.9 0.1 3.2 2 1 0 2 2 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 ORX97931.1 - 0.5 10.4 4.1 14 5.7 0.2 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon ADD_DNMT3 PF17980.1 ORX97931.1 - 0.68 10.0 4.6 0.52 10.3 1.1 2.3 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 ADK_lid PF05191.14 ORX97931.1 - 1.6 8.8 5.3 4.8 7.2 0.2 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 ORX97931.1 - 2.2 8.0 7.3 1.7 8.3 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 ORX97931.1 - 2.6 8.1 6.6 3.5 7.7 1.8 2.9 1 1 1 2 2 2 0 CpXC protein zf-ribbon_3 PF13248.6 ORX97931.1 - 6.3 6.3 8.0 16 5.1 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Moulting_cycle PF04870.16 ORX97931.1 - 8.2 5.6 11.8 0.18 11.1 4.8 1.6 2 0 0 2 2 2 0 Moulting cycle Sel1 PF08238.12 ORX97932.1 - 1.4e-26 92.3 5.1 0.001 19.7 0.1 5.4 5 0 0 5 5 5 5 Sel1 repeat CS PF04969.16 ORX97932.1 - 3.4e-10 40.8 0.0 6.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 CS domain MIT PF04212.18 ORX97932.1 - 0.00093 19.2 2.5 0.37 10.9 0.1 3.1 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 ORX97932.1 - 0.001 18.8 1.6 0.044 13.6 0.4 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORX97932.1 - 0.0041 17.1 2.7 0.081 13.1 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX97932.1 - 0.012 16.2 1.5 1.5 9.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PaRep2a PF07903.11 ORX97932.1 - 0.036 13.9 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 PaRep2a protein DSPc PF00782.20 ORX97933.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORX97933.1 - 8.5e-05 22.3 0.1 0.00012 21.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 ORX97933.1 - 0.0054 16.3 0.0 0.014 15.0 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ORX97933.1 - 0.0063 16.1 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 ORX97933.1 - 0.026 14.7 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 ORX97933.1 - 0.027 14.4 0.1 0.037 14.0 0.1 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family NUDIX PF00293.28 ORX97934.1 - 1.7e-16 60.4 0.2 3.6e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain zf-H2C2_2 PF13465.6 ORX97934.1 - 0.011 16.1 3.9 0.038 14.4 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain CTU2 PF10288.9 ORX97935.1 - 7.8e-25 87.3 1.4 7.8e-25 87.3 1.4 1.8 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 ORX97935.1 - 0.012 15.4 0.0 0.12 12.1 0.0 2.3 1 1 0 2 2 2 0 PP-loop family Phage_lysozyme PF00959.19 ORX97935.1 - 0.13 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage lysozyme DeoC PF01791.9 ORX97936.1 - 2.4e-12 47.0 0.3 3.8e-12 46.3 0.3 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase MFS_1 PF07690.16 ORX97937.1 - 9.6e-41 139.9 60.2 3.6e-35 121.5 32.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORX97937.1 - 6.7e-06 25.9 4.5 6.7e-06 25.9 4.5 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Trp_oprn_chp PF09534.10 ORX97937.1 - 0.00048 20.0 0.4 0.13 12.0 0.1 2.7 2 1 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Baculo_LEF-3 PF05847.11 ORX97937.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) DUF3493 PF11998.8 ORX97937.1 - 2.3 8.4 5.2 3.9 7.7 0.8 3.1 3 1 1 4 4 4 0 Low psii accumulation1 / Rep27 Abhydrolase_6 PF12697.7 ORX97939.1 - 1.4e-17 65.0 1.2 1.7e-17 64.8 1.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ORX97939.1 - 3e-08 33.7 0.1 3e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 ORX97939.1 - 2.3e-05 24.2 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX97939.1 - 7.1e-05 22.6 1.0 0.021 14.5 1.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX97939.1 - 0.0099 15.2 0.1 0.19 11.0 0.0 2.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DUF433 PF04255.14 ORX97939.1 - 0.048 13.5 0.1 0.3 11.0 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF433) Thioesterase PF00975.20 ORX97939.1 - 0.11 12.5 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Latrotoxin_C PF15658.6 ORX97968.1 - 0.00029 20.6 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 Latrotoxin C-terminal domain ThiJ_like PF17124.5 ORX97968.1 - 0.0065 16.2 0.0 0.0074 16.0 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like NmrA PF05368.13 ORX97969.1 - 2.7e-59 200.6 0.0 3.7e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX97969.1 - 5.6e-22 78.5 0.0 7.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORX97969.1 - 1.4e-08 34.1 0.1 2.6e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORX97969.1 - 2.4e-08 33.8 0.0 4.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORX97969.1 - 0.002 18.1 0.0 0.0042 17.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ORX97969.1 - 0.057 13.9 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX97969.1 - 0.066 13.3 0.1 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PX PF00787.24 ORX97970.1 - 4.5e-15 55.6 0.5 1.1e-14 54.4 0.5 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ORX97970.1 - 3.5e-10 39.8 10.0 3.5e-10 39.8 10.0 1.5 2 0 0 2 2 2 1 Vps5 C terminal like DUF218 PF02698.17 ORX97971.1 - 1.2e-05 25.3 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain DSPc PF00782.20 ORX97972.1 - 1.5e-08 34.5 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORX97972.1 - 3.1e-07 30.2 0.0 4.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORX97972.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RasGAP PF00616.19 ORX97973.1 - 3.9e-14 52.9 0.3 2.7e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 ORX97973.1 - 1.2e-12 48.0 0.0 2.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 ORX97973.1 - 4.9e-09 36.7 0.4 1e-08 35.6 0.4 1.5 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 ORX97973.1 - 7.1e-07 29.2 0.1 1.6e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH_2 PF08458.10 ORX97973.1 - 0.00039 20.7 0.1 0.0009 19.6 0.1 1.6 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_13 PF16652.5 ORX97973.1 - 0.056 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 ORX97973.1 - 0.072 13.4 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_16 PF00722.21 ORX97974.1 - 9.6e-32 109.9 0.2 1.2e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MAS20 PF02064.15 ORX97977.1 - 1.1e-35 122.6 0.6 3.8e-35 120.8 0.0 2.3 2 0 0 2 2 2 1 MAS20 protein import receptor Ribosomal_L35p PF01632.19 ORX97977.1 - 2.4e-16 60.0 11.6 4.9e-16 59.0 11.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 SET PF00856.28 ORX97977.1 - 5.8e-11 43.1 0.1 8.9e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 SET domain MbeB_N PF04837.12 ORX97977.1 - 0.091 13.1 2.1 12 6.3 0.0 2.8 3 0 0 3 3 3 0 MbeB-like, N-term conserved region TPR_1 PF00515.28 ORX97977.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat P16-Arc PF04699.14 ORX97978.1 - 9.2e-54 182.0 0.5 1e-53 181.8 0.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 ORX97978.1 - 7.9e-05 22.9 0.1 0.00017 21.9 0.0 1.6 2 0 0 2 2 2 1 Dip2/Utp12 Family Sigma70_r3 PF04539.16 ORX97978.1 - 0.0018 18.3 0.2 0.0032 17.5 0.2 1.5 1 1 0 1 1 1 1 Sigma-70 region 3 UTP15_C PF09384.10 ORX97978.1 - 0.0034 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal PP2C_C PF07830.13 ORX97978.1 - 0.98 9.9 3.4 10 6.6 1.2 2.3 1 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain ABC_tran PF00005.27 ORX97979.1 - 1.2e-50 171.6 0.0 8.9e-33 113.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORX97979.1 - 1.5e-35 123.2 41.7 3.4e-19 69.6 16.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 ORX97979.1 - 2.7e-06 27.0 1.9 0.013 15.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORX97979.1 - 8.2e-06 25.9 2.6 0.064 13.3 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX97979.1 - 2.4e-05 24.8 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ORX97979.1 - 4.8e-05 22.9 2.8 0.047 13.1 0.1 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX97979.1 - 5.2e-05 23.2 0.5 0.14 12.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 ORX97979.1 - 0.00061 19.4 0.7 0.37 10.3 0.2 2.5 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 ORX97979.1 - 0.0012 17.9 1.5 0.78 8.7 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 ORX97979.1 - 0.0013 17.9 0.5 0.025 13.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 ORX97979.1 - 0.0013 17.7 2.6 0.058 12.3 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ORX97979.1 - 0.0016 19.0 0.8 1.3 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORX97979.1 - 0.0028 17.3 0.8 2.3 7.8 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 ORX97979.1 - 0.0063 16.4 0.6 8.5 6.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORX97979.1 - 0.011 16.0 0.4 3.3 8.0 0.1 3.0 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORX97979.1 - 0.013 15.6 0.3 0.013 15.6 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 ORX97979.1 - 0.03 14.1 5.3 0.43 10.3 0.2 3.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORX97979.1 - 0.04 13.6 1.1 8.8 6.0 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 ORX97979.1 - 0.064 13.2 2.1 5.7 6.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 ORX97979.1 - 0.069 13.4 0.6 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORX97979.1 - 0.074 13.1 5.0 1.3 9.1 0.3 2.7 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 ORX97979.1 - 0.09 12.0 1.7 2.1 7.6 0.4 2.4 2 0 0 2 2 2 0 Zeta toxin CbiA PF01656.23 ORX97979.1 - 0.11 12.6 1.9 0.59 10.2 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 ORX97979.1 - 0.14 11.8 0.2 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORX97979.1 - 0.26 11.2 1.9 20 5.1 0.0 3.3 3 0 0 3 3 3 0 NTPase MobB PF03205.14 ORX97979.1 - 0.27 11.2 2.5 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 ORX97979.1 - 0.28 11.2 1.0 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 ORX97979.1 - 0.73 9.1 4.0 0.87 8.9 0.2 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 ORX97979.1 - 1.2 8.3 3.3 3.7 6.7 0.4 2.4 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORX97979.1 - 3.8 7.0 5.4 5 6.6 0.1 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Mito_carr PF00153.27 ORX97980.1 - 9e-24 83.2 0.6 8.4e-12 44.9 0.0 4.6 3 2 1 4 4 4 4 Mitochondrial carrier protein HEAT PF02985.22 ORX97981.1 - 3e-18 64.3 14.8 0.0061 16.7 0.0 9.0 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 ORX97981.1 - 2.1e-08 34.4 3.5 4.5 7.7 0.0 6.5 5 2 0 5 5 5 3 HEAT repeats Cnd1 PF12717.7 ORX97981.1 - 3.8e-07 30.3 6.0 0.081 13.0 0.0 5.2 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORX97981.1 - 1.7e-05 24.5 0.8 0.068 12.7 0.0 4.1 5 0 0 5 5 5 1 CLASP N terminal HEAT_EZ PF13513.6 ORX97981.1 - 3.7e-05 24.1 1.3 2.2 8.9 0.0 5.6 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 ORX97981.1 - 0.00037 19.2 4.3 0.021 13.4 0.3 3.4 2 1 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 ORX97981.1 - 0.0006 20.4 1.2 3.9 8.1 0.0 5.1 4 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region Gate PF07670.14 ORX97981.1 - 0.13 12.6 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 Nucleoside recognition Abhydrolase_1 PF00561.20 ORX97982.1 - 8.6e-08 32.1 0.0 3.3e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX97982.1 - 2.5e-06 28.2 0.4 3.4e-06 27.8 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX97982.1 - 1.5e-05 24.4 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 ORX97982.1 - 0.23 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Robl_LC7 PF03259.17 ORX97982.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain GPI-anchored PF10342.9 ORX97983.1 - 8e-08 32.9 0.8 2.2e-07 31.5 0.1 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.32 ORX97984.1 - 5.3e-10 39.7 13.5 4.4e-05 24.1 0.8 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX97984.1 - 0.013 15.7 0.1 0.05 13.9 0.1 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 ORX97985.1 - 4.2e-06 26.5 0.1 0.00012 21.8 0.0 2.5 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX97985.1 - 0.021 14.9 0.1 0.088 12.9 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain HA2 PF04408.23 ORX97986.1 - 2.9e-17 62.9 1.1 1.5e-16 60.7 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORX97986.1 - 8.6e-16 58.1 0.0 1.9e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORX97986.1 - 6.1e-15 55.5 0.0 2.3e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORX97986.1 - 3.7e-09 36.6 0.0 8.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 ORX97986.1 - 0.01 15.2 1.1 0.037 13.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 ORX97986.1 - 0.011 16.1 0.1 0.047 14.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORX97986.1 - 0.013 15.8 0.1 0.077 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORX97986.1 - 0.076 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein dsRBD2 PF17842.1 ORX97986.1 - 0.17 12.0 0.0 0.17 12.0 0.0 3.2 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 ABC_tran PF00005.27 ORX97986.1 - 0.24 11.9 4.5 0.75 10.3 0.0 3.3 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 ORX97986.1 - 0.29 11.6 0.0 0.29 11.6 0.0 3.9 3 1 0 3 3 3 0 AAA domain CutA1 PF03091.15 ORX97987.1 - 0.2 11.6 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Arrestin_C PF02752.22 ORX97988.1 - 1.6e-13 51.3 1.7 1.9e-12 47.8 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORX97988.1 - 1.2e-06 28.0 0.4 0.0008 18.7 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 ORX97988.1 - 3.5e-06 27.1 0.1 3.9e-05 23.8 0.1 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX97988.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 Arrestin_N terminal like PQ-loop PF04193.14 ORX97989.1 - 7.2e-36 121.8 12.6 5e-19 67.8 3.9 3.4 4 0 0 4 4 4 2 PQ loop repeat Phage_holin_7_1 PF16081.5 ORX97989.1 - 0.13 12.4 0.2 0.2 11.8 0.2 1.2 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2530 PF10745.9 ORX97989.1 - 1.7 8.9 5.3 1.3 9.3 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) HlyIII PF03006.20 ORX97990.1 - 1e-60 205.3 25.5 1.3e-60 205.0 25.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related GARP PF16731.5 ORX97990.1 - 0.2 11.3 0.7 0.27 10.9 0.7 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF3493 PF11998.8 ORX97990.1 - 1.1 9.5 3.6 1.8 8.8 0.5 2.4 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Yip1 PF04893.17 ORX97991.1 - 2.1e-10 40.6 14.8 5.4e-10 39.2 13.7 1.9 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 ORX97991.1 - 0.41 10.1 11.7 23 4.4 11.7 2.3 1 1 0 1 1 1 0 YIF1 GyrB_insert PF18053.1 ORX97992.1 - 0.0064 16.4 0.5 0.0069 16.3 0.5 1.0 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain FliX PF10768.9 ORX97992.1 - 0.12 12.9 1.6 0.14 12.6 1.6 1.2 1 0 0 1 1 1 0 Class II flagellar assembly regulator TALPID3 PF15324.6 ORX97992.1 - 0.17 9.5 2.3 0.17 9.5 2.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target zf-RING_5 PF14634.6 ORX97993.1 - 3.1e-07 30.2 11.9 5.4e-07 29.5 11.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORX97993.1 - 2.7e-05 23.9 7.3 5.2e-05 23.0 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORX97993.1 - 0.00014 22.1 10.8 0.00027 21.2 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX97993.1 - 0.00015 21.5 5.5 0.00035 20.4 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORX97993.1 - 0.00049 19.9 9.7 0.00085 19.1 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORX97993.1 - 0.002 17.9 6.3 0.0037 17.1 6.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORX97993.1 - 0.008 16.0 3.4 0.016 15.0 3.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ORX97993.1 - 0.044 14.1 6.1 0.076 13.3 6.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 ORX97993.1 - 0.054 13.6 8.6 0.063 13.4 7.5 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 ORX97993.1 - 0.058 13.3 9.1 0.11 12.4 9.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 ORX97993.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein zf-P11 PF03854.14 ORX97993.1 - 0.12 12.0 3.9 0.19 11.4 3.5 1.6 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 ORX97993.1 - 0.17 12.1 5.6 0.37 11.0 5.6 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 ORX97993.1 - 0.61 10.2 7.7 0.45 10.6 5.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Mad3_BUB1_I PF08311.12 ORX97994.1 - 8.2e-34 116.3 1.5 2e-33 115.0 1.5 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 ORX97994.1 - 0.00012 22.2 1.0 0.00073 19.7 0.1 2.8 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 ORX97994.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein LMBR1 PF04791.16 ORX97995.1 - 3.5e-126 422.1 21.1 4e-126 421.9 21.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Cofilin_ADF PF00241.20 ORX97996.1 - 5.2e-36 123.1 0.0 2.5e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein 2OG-FeII_Oxy_2 PF13532.6 ORX97997.1 - 4.9e-25 88.9 0.0 6.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PLA2G12 PF06951.11 ORX97998.1 - 1.5e-05 25.0 16.8 2.9e-05 24.0 16.7 1.4 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Mob1_phocein PF03637.17 ORX97999.1 - 9.1e-16 58.3 0.9 1.3e-15 57.8 0.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_S2 PF00318.20 ORX98000.1 - 6.8e-29 100.6 0.6 3.3e-14 52.7 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORX98000.1 - 5e-06 27.8 17.9 1.2e-05 26.5 17.9 1.7 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_L27e PF01777.18 ORX98001.1 - 5.5e-37 126.0 8.1 5.5e-37 126.0 8.1 1.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 ORX98001.1 - 0.0024 17.8 0.5 0.0024 17.8 0.5 1.9 2 0 0 2 2 2 1 KOW motif His_Phos_1 PF00300.22 ORX98002.1 - 1.3e-42 145.7 0.0 2.8e-42 144.6 0.0 1.5 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 ORX98003.1 - 4.5e-40 137.7 67.8 9.5e-28 97.1 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORX98003.1 - 4.6e-06 26.2 28.7 5.7e-06 25.9 28.7 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORX98003.1 - 2.4e-05 23.4 25.9 0.0099 14.8 11.3 2.9 2 2 0 2 2 2 2 MFS_1 like family Thioredoxin PF00085.20 ORX98004.1 - 5e-20 71.4 0.0 6.6e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORX98004.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORX98004.1 - 0.013 16.0 0.0 0.031 14.7 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORX98004.1 - 0.02 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 ORX98004.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family FeoB_associated PF12669.7 ORX98004.1 - 0.097 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Doppel PF11466.8 ORX98004.1 - 0.21 11.3 0.8 0.39 10.4 0.8 1.4 1 0 0 1 1 1 0 Prion-like protein Doppel B56 PF01603.20 ORX98005.1 - 3.4e-186 619.2 6.1 4.5e-186 618.8 6.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) zf-rbx1 PF12678.7 ORX98007.1 - 1.3e-07 31.8 5.0 3.9e-07 30.3 4.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORX98007.1 - 1.8e-05 24.5 4.5 4.7e-05 23.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX98007.1 - 2.2e-05 24.7 6.6 6.6e-05 23.2 6.6 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORX98007.1 - 0.00015 21.7 6.0 0.00045 20.2 1.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 ORX98007.1 - 0.00016 21.7 4.2 0.00036 20.6 1.5 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 ORX98007.1 - 0.00022 21.2 4.8 0.0006 19.8 4.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1993 PF09351.10 ORX98007.1 - 0.0012 19.0 1.9 0.0012 19.0 1.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1993) zf-C3HC4_2 PF13923.6 ORX98007.1 - 0.0055 16.5 6.4 0.0075 16.1 0.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX98007.1 - 0.014 15.3 3.8 0.041 13.9 3.8 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORX98007.1 - 0.024 14.8 3.0 0.096 12.9 0.8 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING GP3_package PF16677.5 ORX98007.1 - 0.042 14.0 0.4 0.093 12.9 0.4 1.6 1 0 0 1 1 1 0 DNA-packaging protein gp3 zf-RING_11 PF17123.5 ORX98007.1 - 0.054 13.3 1.0 0.054 13.3 1.0 3.2 3 0 0 3 3 3 0 RING-like zinc finger Prok-RING_4 PF14447.6 ORX98007.1 - 0.066 13.1 4.4 0.32 10.9 4.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORX98007.1 - 0.18 11.4 4.0 0.16 11.6 1.9 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type ThiS PF02597.20 ORX98007.1 - 0.26 12.0 4.6 1.4 9.6 1.3 3.0 2 1 0 2 2 2 0 ThiS family GP41 PF00517.17 ORX98007.1 - 0.39 10.6 10.4 2.3 8.1 0.8 2.2 1 1 1 2 2 2 0 Retroviral envelope protein DUF1178 PF06676.11 ORX98007.1 - 0.59 10.5 9.7 1.8e+02 2.5 9.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) PHD_Oberon PF07227.11 ORX98007.1 - 2 8.3 6.3 0.43 10.5 2.7 1.9 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein FlaC_arch PF05377.11 ORX98007.1 - 4.5 7.7 10.9 9.2 6.7 1.2 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3847 PF12958.7 ORX98007.1 - 7 6.8 26.6 0.13 12.4 6.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3847) DUF1216 PF06746.11 ORX98007.1 - 9.4 6.3 15.2 0.22 11.5 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) Peptidase_M28 PF04389.17 ORX98008.1 - 2.5e-38 131.7 0.0 3.6e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORX98008.1 - 8.8e-13 48.1 0.3 2e-12 47.0 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORX98008.1 - 0.00023 20.9 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CBAH PF02275.18 ORX98009.1 - 0.015 14.9 0.2 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF3472 PF11958.8 ORX98038.1 - 2.1e-13 51.1 1.3 3.8e-13 50.3 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX98038.1 - 2.4e-07 31.1 14.1 5.6e-07 29.9 14.1 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF4937 PF16291.5 ORX98038.1 - 0.013 15.7 0.4 0.032 14.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 DUF3472 PF11958.8 ORX98039.1 - 6.9e-12 46.2 5.9 1.1e-11 45.5 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX98039.1 - 0.0035 17.3 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF3336 PF11815.8 ORX98040.1 - 6.8e-31 106.8 0.2 1.3e-30 105.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORX98040.1 - 1e-21 78.1 0.0 1.6e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Tom37 PF10568.9 ORX98041.1 - 4.1e-34 117.6 0.3 6e-34 117.1 0.3 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORX98041.1 - 1.7e-21 75.7 0.0 3.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORX98041.1 - 8.6e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORX98041.1 - 8.7e-06 25.7 0.1 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98041.1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX98041.1 - 0.00096 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1356 PF07092.12 ORX98043.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1356) Linker_histone PF00538.19 ORX98044.1 - 3.1e-29 101.2 0.1 3.1e-29 101.2 0.1 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Aldedh PF00171.22 ORX98045.1 - 1.2e-158 528.4 0.0 1.4e-158 528.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SEP PF08059.13 ORX98046.1 - 3.5e-26 91.6 0.4 1.5e-25 89.6 0.0 2.2 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 ORX98046.1 - 1.9e-17 62.8 1.5 3.7e-17 61.9 1.5 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 ORX98046.1 - 9.1e-17 61.0 0.1 1.6e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 ORX98046.1 - 0.00024 20.7 0.1 0.00042 19.9 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain Ras PF00071.22 ORX98049.1 - 2.2e-63 212.7 0.2 2.6e-63 212.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX98049.1 - 4.9e-36 123.6 0.1 7.4e-36 123.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX98049.1 - 8e-14 51.5 0.1 9.5e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX98049.1 - 9.2e-08 32.2 0.1 1.6e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX98049.1 - 6.2e-05 23.0 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORX98049.1 - 0.0003 20.4 0.1 0.001 18.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORX98049.1 - 0.00039 19.9 0.0 0.00067 19.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 ORX98049.1 - 0.0024 18.1 0.1 0.024 14.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX98049.1 - 0.0047 17.3 0.1 0.0075 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ORX98049.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ORX98049.1 - 0.023 15.2 0.2 0.03 14.8 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 ORX98049.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 ORX98049.1 - 0.056 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MgpC PF05220.12 ORX98049.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 MgpC protein precursor AAA_24 PF13479.6 ORX98049.1 - 0.066 12.9 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORX98049.1 - 0.069 13.2 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ORX98049.1 - 0.074 12.3 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain FeoB_N PF02421.18 ORX98049.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 ORX98049.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 ORX98049.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 ORX98049.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 ORX98051.1 - 9.6e-15 54.7 2.5 4.4e-06 27.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98051.1 - 2.9e-11 43.5 0.0 0.0045 17.3 0.0 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Adaptin_N PF01602.20 ORX98052.1 - 4.5e-146 487.5 2.5 5.5e-146 487.2 2.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORX98052.1 - 5.5e-25 87.8 0.5 1.1e-24 86.9 0.5 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORX98052.1 - 7.8e-11 42.3 10.6 2.1e-09 37.6 0.6 4.0 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORX98052.1 - 1.5e-07 31.7 1.8 0.4 11.1 0.0 5.2 4 1 0 4 4 4 2 HEAT repeats API5 PF05918.11 ORX98052.1 - 9.9e-05 21.3 0.4 0.0034 16.3 0.3 2.3 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) DNA_alkylation PF08713.11 ORX98052.1 - 0.019 14.7 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 DNA alkylation repair enzyme HEAT PF02985.22 ORX98052.1 - 0.071 13.4 5.3 13 6.4 0.1 5.6 5 1 1 6 6 6 0 HEAT repeat ParcG PF10274.9 ORX98052.1 - 0.2 11.8 1.0 0.45 10.6 0.1 2.1 2 1 0 2 2 2 0 Parkin co-regulated protein Ras PF00071.22 ORX98053.1 - 5e-56 188.8 0.1 5.8e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX98053.1 - 9.1e-21 74.3 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX98053.1 - 1.8e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX98053.1 - 1.1e-05 25.0 0.2 0.00016 21.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORX98053.1 - 0.00043 20.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORX98053.1 - 0.0078 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX98053.1 - 0.01 15.4 0.2 0.13 11.8 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 ORX98053.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 ORX98053.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORX98053.1 - 0.085 12.9 0.3 0.16 12.0 0.3 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORX98053.1 - 0.16 12.4 0.1 0.29 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF2431 PF10354.9 ORX98055.1 - 8.7e-53 179.0 0.0 1.2e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltr_RsmB-F PF01189.17 ORX98055.1 - 0.05 13.2 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CobT PF06213.12 ORX98056.1 - 1.2 8.5 9.9 1.3 8.3 9.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 ORX98056.1 - 2 6.6 8.9 2.1 6.5 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 ORX98056.1 - 3.6 6.6 17.0 3.8 6.5 17.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rep_4 PF05797.11 ORX98056.1 - 4.4 6.3 5.7 4.7 6.2 5.7 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Pkinase PF00069.25 ORX98057.1 - 1.6e-31 109.6 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98057.1 - 2.1e-07 30.5 0.0 2.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX98057.1 - 0.00033 19.6 0.0 0.00047 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX98057.1 - 0.00049 20.1 1.4 0.0009 19.2 1.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX98057.1 - 0.0041 16.5 1.1 0.0064 15.9 1.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORX98057.1 - 0.042 12.9 0.6 0.079 12.0 0.6 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 ORX98057.1 - 0.044 13.4 1.5 0.07 12.7 1.5 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 ORX98057.1 - 0.044 13.1 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 ORX98057.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 RIO1 family IPP-2 PF04979.14 ORX98058.1 - 3.4e-21 76.4 6.3 4.6e-21 75.9 6.3 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) zf-CCCH PF00642.24 ORX98059.1 - 2e-20 72.2 15.8 6.3e-12 45.1 2.1 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORX98059.1 - 6.6e-10 38.7 16.0 1.1e-06 28.5 1.8 2.4 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORX98059.1 - 8.6e-07 28.6 13.4 0.0024 17.6 6.3 2.5 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORX98059.1 - 0.002 18.8 8.7 0.14 12.8 2.6 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 ORX98059.1 - 0.062 13.8 0.2 0.062 13.8 0.2 2.8 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CLIP_SPH_mas PF18398.1 ORX98059.1 - 0.12 12.9 0.9 0.12 12.9 0.9 2.0 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade DUF1289 PF06945.13 ORX98061.1 - 0.11 12.4 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) ABC_membrane PF00664.23 ORX98063.1 - 9.3e-125 415.8 21.5 2.3e-66 224.2 4.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORX98063.1 - 6e-70 234.1 0.1 2.5e-35 122.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORX98063.1 - 2.1e-16 60.0 2.2 2.5e-05 23.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORX98063.1 - 1.3e-09 37.7 0.3 0.002 17.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX98063.1 - 1.6e-09 38.3 0.8 0.0015 19.0 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORX98063.1 - 2.5e-07 30.7 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 ORX98063.1 - 3.9e-07 29.2 0.2 0.005 15.7 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORX98063.1 - 1.8e-06 28.3 2.4 0.014 15.6 0.1 4.3 4 1 0 4 4 3 2 AAA domain AAA PF00004.29 ORX98063.1 - 5.5e-06 26.8 0.9 2.1 8.7 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ORX98063.1 - 1.9e-05 24.6 2.2 0.033 13.9 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 ORX98063.1 - 3.8e-05 23.5 1.3 0.43 10.3 0.1 3.7 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORX98063.1 - 0.00012 22.2 4.5 0.3 11.4 0.5 4.4 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ORX98063.1 - 0.00023 21.1 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 ORX98063.1 - 0.00026 21.0 0.2 1 9.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 ORX98063.1 - 0.00048 19.4 0.0 0.7 9.0 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit IstB_IS21 PF01695.17 ORX98063.1 - 0.00061 19.6 1.0 4.3 7.0 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.6 ORX98063.1 - 0.00083 19.6 0.1 2.4 8.4 0.0 3.9 3 1 1 4 4 3 1 AAA domain MMR_HSR1 PF01926.23 ORX98063.1 - 0.00095 19.2 0.1 1.6 8.9 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_7 PF12775.7 ORX98063.1 - 0.0011 18.6 0.0 0.68 9.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_21 PF13304.6 ORX98063.1 - 0.0012 18.8 1.5 3.4 7.4 0.0 4.4 4 1 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ORX98063.1 - 0.0013 18.9 0.0 2.9 8.0 0.1 3.2 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 ORX98063.1 - 0.0016 17.7 0.0 0.36 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORX98063.1 - 0.0028 18.2 0.0 5.9 7.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 ORX98063.1 - 0.0031 16.7 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 ORX98063.1 - 0.0037 17.2 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 ORX98063.1 - 0.0063 15.8 0.1 3.8 6.7 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin Halogen_Hydrol PF10112.9 ORX98063.1 - 0.012 15.6 2.8 0.44 10.5 0.2 3.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein AAA_24 PF13479.6 ORX98063.1 - 0.015 15.0 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORX98063.1 - 0.016 14.8 0.2 7.1 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORX98063.1 - 0.02 15.4 8.7 1 9.8 0.0 4.0 5 0 0 5 5 3 0 AAA domain Mg_chelatase PF01078.21 ORX98063.1 - 0.027 13.9 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 ORX98063.1 - 0.029 14.5 0.4 2.8 8.0 0.1 3.2 3 0 0 3 3 2 0 Helicase HerA, central domain GHMP_kinases_C PF08544.13 ORX98063.1 - 0.047 14.1 0.0 0.26 11.7 0.0 2.3 2 0 0 2 2 1 0 GHMP kinases C terminal NACHT PF05729.12 ORX98063.1 - 0.048 13.6 1.1 13 5.6 0.0 3.1 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 ORX98063.1 - 0.05 14.0 0.0 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 ORX98063.1 - 0.06 13.1 0.0 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 ORX98063.1 - 0.073 12.8 0.0 8.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2057 PF09829.9 ORX98063.1 - 0.093 12.9 0.3 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TniB PF05621.11 ORX98063.1 - 0.12 11.7 0.1 25 4.2 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein DUF2207 PF09972.9 ORX98063.1 - 2.3 6.9 14.6 0.39 9.4 0.0 4.1 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) Uricase PF01014.18 ORX98064.1 - 3.7e-10 40.1 0.1 1.2e-07 32.1 0.1 2.2 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORX98065.1 - 7.2e-16 58.6 1.5 1.6e-11 44.6 0.0 3.0 2 1 1 3 3 3 3 Uricase DUF3472 PF11958.8 ORX98066.1 - 5e-13 49.9 1.6 9e-13 49.1 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORX98066.1 - 2.5e-07 31.0 14.1 6.1e-07 29.8 14.1 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF4937 PF16291.5 ORX98066.1 - 0.014 15.7 0.4 0.035 14.3 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 Chitin_synth_2 PF03142.15 ORX98091.1 - 2e-280 930.9 2.0 2.3e-280 930.7 2.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX98091.1 - 4.7e-15 56.1 0.1 3.7e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX98091.1 - 1.1e-11 45.1 12.4 6.8e-11 42.4 12.4 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORX98091.1 - 0.00012 21.6 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORX98091.1 - 0.00034 20.5 0.0 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF4229 PF14012.6 ORX98091.1 - 0.4 10.8 6.6 1.2 9.3 6.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4519 PF15012.6 ORX98091.1 - 0.85 9.8 5.8 3.2 8.0 5.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ERO1 PF04137.15 ORX98092.1 - 6.4e-80 269.0 0.3 7.2e-80 268.8 0.3 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF3966 PF13110.6 ORX98092.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) SGL PF08450.12 ORX98094.1 - 3.9e-24 85.6 0.1 5.7e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORX98094.1 - 2.2e-05 24.5 0.1 0.00052 20.2 0.0 2.9 3 0 0 3 3 3 1 Arylesterase Str_synth PF03088.16 ORX98094.1 - 0.0013 18.8 0.0 0.031 14.4 0.0 2.7 2 1 0 2 2 2 1 Strictosidine synthase EcoRII-N PF09217.10 ORX98095.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal PH PF00169.29 ORX98096.1 - 2.4e-09 37.6 0.5 3.8e-09 37.0 0.5 1.3 1 0 0 1 1 1 1 PH domain RA PF00788.23 ORX98096.1 - 0.0001 22.8 0.0 0.00026 21.6 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FAA_hydrolase PF01557.18 ORX98097.1 - 2e-71 240.1 0.0 2.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RhoGEF PF00621.20 ORX98098.1 - 2.2e-40 138.8 0.5 2.2e-40 138.8 0.5 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_13 PF16652.5 ORX98098.1 - 0.0018 18.1 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ku_PK_bind PF08785.11 ORX98098.1 - 0.004 17.3 0.2 0.019 15.1 0.1 2.1 1 1 1 2 2 2 1 Ku C terminal domain like Thioredoxin_4 PF13462.6 ORX98100.1 - 5.5e-10 39.7 0.0 1.1e-09 38.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ORX98100.1 - 0.00013 21.8 0.0 0.26 11.0 0.1 2.3 1 1 0 2 2 2 2 DSBA-like thioredoxin domain YcbB PF08664.10 ORX98100.1 - 0.093 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 YcbB domain RabGAP-TBC PF00566.18 ORX98101.1 - 1.3e-31 110.0 8.7 3.5e-15 56.2 0.0 3.1 1 1 1 2 2 2 2 Rab-GTPase-TBC domain zf-A20 PF01754.16 ORX98101.1 - 0.17 11.8 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 A20-like zinc finger Pkinase PF00069.25 ORX98102.1 - 1.2e-73 247.8 0.0 1.5e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98102.1 - 6.4e-34 117.4 0.0 8.4e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX98102.1 - 5.7e-10 39.0 0.0 9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX98102.1 - 5.6e-05 22.1 3.6 0.00018 20.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORX98102.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORX98102.1 - 0.0035 16.7 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 ORX98102.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ABC1 PF03109.16 ORX98102.1 - 0.014 15.6 0.4 0.076 13.2 0.3 2.1 1 1 1 2 2 2 0 ABC1 family YrbL-PhoP_reg PF10707.9 ORX98102.1 - 0.047 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Plectin PF00681.20 ORX98102.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat VHL PF01847.16 ORX98102.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 VHL beta domain HAD PF12710.7 ORX98103.1 - 8.4e-17 62.2 0.0 1.2e-16 61.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ORX98103.1 - 1.3e-05 24.7 0.0 3.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 ORX98103.1 - 0.0063 16.6 0.3 6.1 6.9 0.1 3.3 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 ORX98103.1 - 0.0065 16.0 0.0 0.022 14.3 0.0 1.7 1 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 ORX98103.1 - 0.021 15.1 0.1 0.43 10.8 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 ORX98139.1 - 2e-65 216.7 3.4 2.5e-24 85.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 ORX98139.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Fuseless eIF3m_C_helix PF18005.1 ORX98139.1 - 0.07 12.9 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Tim17 PF02466.19 ORX98140.1 - 1.1e-32 112.7 5.2 1.3e-32 112.4 5.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sua5_yciO_yrdC PF01300.18 ORX98141.1 - 9.9e-55 184.8 0.0 1.6e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ORX98141.1 - 4.6e-34 117.9 0.0 7.2e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DSS1_SEM1 PF05160.13 ORX98142.1 - 3.2e-24 84.7 20.9 3.9e-24 84.5 20.9 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 ORX98143.1 - 5.4e-61 204.8 0.0 2.1e-44 151.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX98143.1 - 9.5e-10 38.1 0.4 1.9e-05 24.4 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 ORX98143.1 - 3.4e-06 27.5 0.7 0.015 15.7 0.0 4.0 3 2 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ORX98143.1 - 0.00045 20.0 0.0 0.0033 17.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORX98143.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORX98143.1 - 0.0019 18.5 0.2 0.069 13.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX98143.1 - 0.0028 17.8 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 ORX98143.1 - 0.0035 17.3 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 ORX98143.1 - 0.0045 16.1 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 SKI PF01202.22 ORX98143.1 - 0.0045 17.1 0.1 0.42 10.7 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase TIP49 PF06068.13 ORX98143.1 - 0.0065 15.7 0.2 0.064 12.4 0.0 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_18 PF13238.6 ORX98143.1 - 0.0069 16.9 0.0 0.097 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ORX98143.1 - 0.008 15.5 0.0 0.083 12.2 0.0 2.5 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 ORX98143.1 - 0.0082 15.7 0.1 0.1 12.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ORX98143.1 - 0.0096 15.9 0.1 0.17 11.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ORX98143.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORX98143.1 - 0.013 14.9 0.1 0.039 13.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORX98143.1 - 0.013 15.0 0.0 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 ORX98143.1 - 0.027 14.5 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ORX98143.1 - 0.038 14.4 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin2 PF13189.6 ORX98143.1 - 0.044 13.9 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase-like family Sigma54_activat PF00158.26 ORX98143.1 - 0.044 13.5 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 ORX98143.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CDC48_2 PF02933.17 ORX98143.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_28 PF13521.6 ORX98143.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NDK PF00334.19 ORX98144.1 - 1.7e-45 154.3 0.0 1.9e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase AMP-binding PF00501.28 ORX98146.1 - 7.8e-93 311.4 0.0 9.9e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX98146.1 - 3.8e-23 82.2 0.7 1.5e-22 80.3 0.3 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORX98146.1 - 4.8e-19 68.0 0.1 1.2e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Methyltransf_25 PF13649.6 ORX98147.1 - 9.3e-15 55.1 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX98147.1 - 2.6e-14 53.3 0.1 3.5e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX98147.1 - 4.2e-11 43.4 0.0 6.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX98147.1 - 1.5e-10 41.7 0.0 2.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX98147.1 - 3.3e-06 27.0 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 ORX98147.1 - 1e-05 24.8 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme CheR PF01739.18 ORX98147.1 - 0.00017 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 ORX98147.1 - 0.0028 17.0 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ORX98147.1 - 0.0045 16.3 0.0 0.0059 15.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 ORX98147.1 - 0.007 15.7 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORX98147.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain CBFB_NFYA PF02045.15 ORX98148.1 - 1.6e-29 102.2 7.5 3.1e-29 101.4 7.5 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B tRNA_NucTransf2 PF09249.11 ORX98148.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain ddrB-ParB PF18763.1 ORX98148.1 - 0.039 14.1 0.2 0.065 13.3 0.2 1.4 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain RNase_P_pop3 PF08228.11 ORX98149.1 - 1.1e-09 38.6 0.1 4.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 KCH PF16944.5 ORX98150.1 - 1.3e-62 211.9 23.8 2.9e-62 210.7 23.8 1.5 1 1 0 1 1 1 1 Fungal potassium channel Velvet PF11754.8 ORX98151.1 - 2.8e-43 148.7 0.7 1.9e-30 106.6 0.1 2.0 1 1 1 2 2 2 2 Velvet factor RRS1 PF04939.12 ORX98152.1 - 8.1e-59 198.1 1.6 1.3e-58 197.4 1.6 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RED_N PF07808.13 ORX98153.1 - 6.7e-50 169.9 4.5 6.7e-50 169.9 4.5 2.6 3 1 0 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.11 ORX98153.1 - 1.3 9.6 14.8 3 8.3 6.7 4.2 3 1 0 3 3 3 0 RED-like protein C-terminal region KCH PF16944.5 ORX98155.1 - 1.2e-70 238.2 20.9 1.5e-70 237.8 20.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF747 PF05346.11 ORX98156.1 - 5.2e-111 371.1 9.7 6.7e-111 370.8 9.7 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PDZ_5 PF17817.1 ORX98157.1 - 0.0061 16.8 0.1 0.0077 16.5 0.1 1.2 1 0 0 1 1 1 1 PDZ domain VMA21 PF09446.10 ORX98158.1 - 4.9e-06 26.5 16.8 2.2e-05 24.4 16.8 1.8 1 1 0 1 1 1 1 VMA21-like domain HLH PF00010.26 ORX98159.1 - 6.4e-14 51.6 0.9 1.2e-13 50.8 0.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.18 ORX98159.1 - 0.039 14.3 0.4 0.093 13.1 0.4 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 ORX98159.1 - 0.13 12.2 0.9 0.35 10.8 0.9 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 ORX98159.1 - 0.32 11.5 4.3 0.35 11.4 0.5 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Band_7 PF01145.25 ORX98160.1 - 7.1e-29 101.1 2.0 9.7e-29 100.6 2.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family YueH PF14166.6 ORX98160.1 - 0.088 12.7 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 YueH-like protein KH_1 PF00013.29 ORX98161.1 - 7.6e-139 451.7 50.1 9.3e-17 60.6 0.2 14.5 14 1 0 14 14 14 14 KH domain KH_2 PF07650.17 ORX98161.1 - 5.9e-19 67.7 22.9 0.03 14.1 0.1 10.5 9 2 2 11 11 11 6 KH domain SLS PF14611.6 ORX98161.1 - 6.1e-13 49.1 12.5 0.069 13.0 0.0 7.6 3 3 3 8 8 8 6 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 ORX98161.1 - 0.0016 18.5 16.9 4.6 7.4 0.1 8.1 9 0 0 9 9 9 1 NusA-like KH domain DUF4974 PF16344.5 ORX98161.1 - 0.042 13.9 0.3 21 5.2 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) KH_4 PF13083.6 ORX98161.1 - 0.043 13.7 18.7 1.8 8.5 0.0 8.6 10 1 1 11 11 11 0 KH domain BMC PF00936.19 ORX98161.1 - 0.95 9.5 5.2 5.4 7.1 0.0 4.3 5 0 0 5 5 5 0 BMC domain YbbR PF07949.12 ORX98161.1 - 1 9.8 18.0 1.3 9.5 0.0 7.1 8 0 0 8 8 8 0 YbbR-like protein Homeodomain PF00046.29 ORX98162.1 - 3.3e-17 62.1 6.7 3.5e-17 62.0 6.7 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX98162.1 - 0.0053 16.6 0.4 0.0053 16.6 0.4 1.7 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORX98162.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT NAD_binding_10 PF13460.6 ORX98163.1 - 1.3e-12 48.0 0.2 6.6e-12 45.7 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ORX98163.1 - 1.4e-12 47.6 0.0 2.7e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX98163.1 - 4.7e-11 42.3 0.0 5.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ORX98163.1 - 2.3e-10 40.5 0.5 3.5e-10 39.8 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ORX98163.1 - 2.7e-06 26.6 0.0 5e-06 25.7 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORX98163.1 - 1.7e-05 24.4 0.1 3.9e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORX98163.1 - 1.7e-05 24.2 0.2 3.2e-05 23.2 0.1 1.5 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 ORX98163.1 - 6.6e-05 22.4 0.9 0.00029 20.4 0.7 2.0 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 ORX98163.1 - 0.0013 19.0 0.1 0.0041 17.4 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ORX98163.1 - 0.0059 16.9 0.4 0.028 14.7 0.2 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ORX98163.1 - 0.0071 16.9 1.5 0.014 15.9 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 ORX98163.1 - 0.019 15.1 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 ORX98163.1 - 0.03 13.5 0.4 0.27 10.3 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 ORX98163.1 - 0.11 12.4 2.4 0.28 11.1 1.5 2.1 2 1 0 2 2 2 0 KR domain ADH_zinc_N PF00107.26 ORX98163.1 - 0.18 11.8 1.8 0.33 10.9 0.7 2.0 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Cyclin PF08613.11 ORX98164.1 - 1.4e-10 41.8 0.0 1.6e-09 38.3 0.0 2.2 1 1 0 1 1 1 1 Cyclin MGAT2 PF05060.14 ORX98165.1 - 1.1e-05 24.8 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) GNT-I PF03071.15 ORX98165.1 - 0.00018 20.4 0.1 0.0003 19.7 0.1 1.3 1 1 0 1 1 1 1 GNT-I family Cation_ATPase_C PF00689.21 ORX98166.1 - 1.5e-39 135.6 1.7 1.5e-39 135.6 1.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORX98166.1 - 8.5e-39 132.9 5.0 8.5e-39 132.9 5.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORX98166.1 - 7.9e-18 64.3 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX98166.1 - 1.9e-17 64.3 0.0 2.2e-08 34.6 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX98166.1 - 8.6e-14 51.0 0.0 1.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX98166.1 - 6e-06 26.2 0.1 3.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SH3_1 PF00018.28 ORX98167.1 - 5.6e-10 38.7 0.0 1.3e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORX98167.1 - 6.7e-09 35.5 0.7 7.8e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORX98167.1 - 8.6e-08 31.7 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 ORX98168.1 - 2.7e-08 34.3 0.6 0.3 12.0 0.1 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98168.1 - 0.00047 20.4 0.0 1.1 9.7 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain V-ATPase_G_2 PF16999.5 ORX98168.1 - 0.022 15.1 0.2 0.045 14.2 0.2 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Ima1_N PF09779.9 ORX98168.1 - 0.93 10.4 3.8 1.4 9.7 1.6 2.4 2 0 0 2 2 2 0 Ima1 N-terminal domain UNC-93 PF05978.16 ORX98169.1 - 0.00015 21.5 9.0 0.011 15.5 8.7 2.9 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 Glyco_hydro_47 PF01532.20 ORX98196.1 - 3.1e-123 412.1 0.1 3.7e-123 411.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C2-set_2 PF08205.12 ORX98196.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain bZIP_2 PF07716.15 ORX98197.1 - 7.7e-12 45.1 7.8 7.7e-12 45.1 7.8 2.2 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 ORX98197.1 - 1.3e-05 25.1 5.2 1.3e-05 25.1 5.2 1.6 2 0 0 2 2 2 1 bZIP transcription factor XhlA PF10779.9 ORX98197.1 - 0.12 12.6 2.0 0.22 11.8 2.0 1.5 1 0 0 1 1 1 0 Haemolysin XhlA SRF-TF PF00319.18 ORX98199.1 - 7.4e-22 76.6 0.1 1.2e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SH3_9 PF14604.6 ORX98200.1 - 7.1e-05 22.6 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX98200.1 - 0.00013 21.5 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF2561 PF10812.8 ORX98200.1 - 0.14 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Proteasome PF00227.26 ORX98201.1 - 2.7e-37 128.1 0.0 3.2e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-C2H2 PF00096.26 ORX98202.1 - 1.1e-12 47.7 12.4 7.6e-07 29.3 2.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX98202.1 - 2.5e-09 37.2 10.5 2.4e-05 24.8 2.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORX98202.1 - 1.1e-08 35.1 17.3 2.5e-07 30.8 1.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORX98202.1 - 5.3e-08 33.0 2.3 3.7e-05 24.0 1.1 2.5 2 1 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORX98202.1 - 3.3e-06 27.2 7.1 2.9e-05 24.2 0.6 2.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORX98202.1 - 6.8e-06 25.9 7.4 1.1e-05 25.3 1.4 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 ORX98202.1 - 0.01 15.8 4.9 0.22 11.5 3.4 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.6 ORX98202.1 - 0.021 14.8 0.2 0.021 14.8 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 ORX98202.1 - 0.031 14.6 2.6 0.078 13.3 0.4 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORX98202.1 - 0.036 13.8 6.9 0.58 10.0 1.4 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 ORX98202.1 - 0.14 11.9 9.3 0.47 10.3 1.8 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type Complex1_LYR PF05347.15 ORX98204.1 - 3.4e-21 75.0 0.8 4.2e-21 74.7 0.8 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORX98204.1 - 3.3e-07 30.9 0.3 3.6e-07 30.8 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 ORX98204.1 - 4.7e-07 30.3 0.2 5.4e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like YqfD PF06898.11 ORX98204.1 - 0.036 12.9 0.1 0.039 12.8 0.1 1.0 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD TB2_DP1_HVA22 PF03134.19 ORX98205.1 - 1.1e-29 102.2 7.5 1.5e-29 101.7 7.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 ORX98205.1 - 0.53 10.5 7.7 1 9.6 7.6 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Ras PF00071.22 ORX98206.1 - 5.5e-17 61.8 0.0 3.3e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORX98206.1 - 8e-13 48.7 0.1 1.7e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX98206.1 - 1.4e-06 27.9 0.0 0.00046 19.7 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORX98206.1 - 0.00033 20.7 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX98206.1 - 0.0033 17.3 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ORX98206.1 - 0.01 16.3 0.0 0.012 16.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 ORX98206.1 - 0.016 14.7 0.0 0.075 12.5 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORX98206.1 - 0.035 14.5 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORX98206.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 ORX98206.1 - 0.11 12.3 2.4 0.43 10.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ORX98206.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 ORX98206.1 - 0.16 11.5 0.0 0.36 10.3 0.1 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORX98206.1 - 0.24 10.9 0.2 7.3 6.1 0.4 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4922 PF16269.5 ORX98207.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) Pox_A3L PF05288.11 ORX98208.1 - 0.073 13.1 0.1 0.35 10.9 0.1 2.0 2 0 0 2 2 2 0 Poxvirus A3L Protein Whi5 PF08528.11 ORX98209.1 - 1.8e-09 37.0 0.0 3.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Whi5 like DAAD PF18752.1 ORX98209.1 - 0.078 12.8 2.0 0.097 12.5 2.0 1.2 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase DUF4578 PF15147.6 ORX98209.1 - 0.11 13.4 0.1 0.11 13.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) zf-HC5HC2H_2 PF13832.6 ORX98210.1 - 2.5e-14 53.3 14.4 2.3e-13 50.3 7.2 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain PHD_2 PF13831.6 ORX98210.1 - 2.4e-09 36.6 2.0 2.4e-09 36.6 2.0 2.6 2 1 0 2 2 2 1 PHD-finger PHD PF00628.29 ORX98210.1 - 3.2e-08 33.3 8.3 3.2e-08 33.3 8.3 3.6 2 1 1 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.6 ORX98210.1 - 6.6e-07 29.5 8.4 6.6e-07 29.5 8.4 4.0 2 1 2 4 4 4 2 PHD-like zinc-binding domain KxDL PF10241.9 ORX98210.1 - 0.011 16.0 5.6 0.032 14.5 5.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein P4Ha_N PF08336.11 ORX98210.1 - 0.026 14.5 5.7 7 6.7 0.0 2.8 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3450 PF11932.8 ORX98210.1 - 0.11 11.8 4.4 0.26 10.6 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Myc-LZ PF02344.15 ORX98210.1 - 0.53 10.4 7.6 2.6 8.2 0.9 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain HALZ PF02183.18 ORX98210.1 - 3.6 7.9 6.5 1.7 8.9 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4749 PF15936.5 ORX98218.1 - 0.2 12.8 8.9 0.055 14.6 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4749) Nramp PF01566.18 ORX98219.1 - 2.3e-124 415.0 20.6 2.3e-124 415.0 20.6 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein GDP_Man_Dehyd PF16363.5 ORX98220.1 - 9e-56 189.7 0.0 1.7e-55 188.8 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORX98220.1 - 1.2e-51 175.5 0.1 1.5e-51 175.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORX98220.1 - 2.5e-15 56.4 0.1 1.9e-14 53.5 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORX98220.1 - 1.1e-14 54.2 0.0 4.9e-14 52.0 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORX98220.1 - 2.7e-10 39.8 0.0 3.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORX98220.1 - 3.7e-08 33.5 0.0 6.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ORX98220.1 - 5e-08 32.6 0.0 7.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ORX98220.1 - 5.4e-06 25.8 0.1 0.03 13.5 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORX98220.1 - 0.00095 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX98220.1 - 0.0013 18.3 0.1 0.14 11.7 0.1 2.5 3 0 0 3 3 3 1 NmrA-like family TP_methylase PF00590.20 ORX98221.1 - 5.6e-48 163.7 0.0 1.1e-47 162.7 0.0 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORX98221.1 - 6.5e-22 77.9 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORX98221.1 - 1.6e-18 66.1 0.2 5.4e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORX98221.1 - 5e-07 29.1 0.2 5e-07 29.1 0.2 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central DUF4258 PF14076.6 ORX98221.1 - 0.03 14.7 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) zf-RING_2 PF13639.6 ORX98222.1 - 1.1e-12 48.0 9.8 1.6e-12 47.6 9.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORX98222.1 - 3.3e-09 36.4 9.8 4.8e-09 35.9 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORX98222.1 - 1.3e-08 34.5 9.3 2e-08 33.9 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORX98222.1 - 1.6e-08 34.7 7.8 2.9e-08 33.9 7.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORX98222.1 - 3.6e-08 33.0 6.5 3.6e-08 33.0 6.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ORX98222.1 - 1.5e-07 31.3 8.1 2.1e-07 30.8 8.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORX98222.1 - 4.7e-07 29.7 1.5 4.7e-07 29.7 1.5 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORX98222.1 - 8.1e-06 25.8 4.3 1.6e-05 24.9 4.3 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORX98222.1 - 0.00031 20.5 7.1 0.00044 20.0 7.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORX98222.1 - 0.00034 20.2 5.6 0.00053 19.6 5.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORX98222.1 - 0.00068 19.7 7.4 0.0014 18.7 7.4 1.5 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 ORX98222.1 - 0.0035 17.2 5.7 0.0061 16.4 5.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ORX98222.1 - 0.027 14.3 4.6 0.045 13.6 4.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 ORX98222.1 - 0.03 14.2 5.2 0.067 13.1 5.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORX98222.1 - 0.039 13.8 8.4 0.074 12.9 8.4 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 ORX98222.1 - 0.45 10.7 10.8 4.2 7.6 10.9 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 ORX98222.1 - 2 8.8 10.6 4.8 7.6 10.6 1.7 1 1 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 ORX98222.1 - 9.1 6.4 13.2 0.4 10.8 6.8 2.1 2 1 0 2 2 1 0 Zinc-finger Mito_carr PF00153.27 ORX98223.1 - 6.7e-41 138.1 0.2 2.5e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein LigT_PEase PF02834.16 ORX98224.1 - 0.016 15.4 0.0 0.068 13.4 0.0 2.0 2 0 0 2 2 2 0 LigT like Phosphoesterase BAR PF03114.18 ORX98225.1 - 3.8e-36 124.9 14.8 5.4e-36 124.4 14.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 ORX98225.1 - 2e-15 56.4 0.3 4.7e-15 55.2 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX98225.1 - 3.5e-14 52.1 0.2 6.4e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX98225.1 - 4.9e-11 42.1 0.0 9.3e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ntox28 PF15605.6 ORX98225.1 - 0.15 12.3 3.1 1.1 9.5 1.2 2.5 2 0 0 2 2 2 0 Bacterial toxin 28 SMN PF06003.12 ORX98226.1 - 2.2e-11 43.5 0.1 2.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 ORX98226.1 - 0.00013 22.0 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.6 ORX98226.1 - 0.009 16.0 0.0 0.081 13.0 0.0 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 ORX98226.1 - 0.17 11.7 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Elf1 PF05129.13 ORX98227.1 - 1.2e-29 102.1 4.9 1.5e-29 101.8 4.9 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ras PF00071.22 ORX98228.1 - 1.5e-45 154.7 0.0 2.2e-45 154.1 0.0 1.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORX98228.1 - 4.8e-22 78.4 0.0 6.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX98228.1 - 1.7e-06 27.6 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX98228.1 - 0.23 11.3 0.0 2.5 8.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase SPT_ssu-like PF11779.8 ORX98229.1 - 9.7e-21 73.1 2.5 1.1e-20 73.0 2.5 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ku PF02735.16 ORX98230.1 - 6.9e-40 136.9 0.1 4.1e-38 131.1 0.1 2.2 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORX98230.1 - 2e-26 93.1 1.9 2.2e-23 83.2 0.2 2.7 2 1 1 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ORX98230.1 - 2.1e-15 57.2 0.0 7.4e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm DUF1137 PF06587.11 ORX98230.1 - 0.021 14.8 0.0 5.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) HSV_VP16_C PF12149.8 ORX98230.1 - 0.18 11.9 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal RA PF00788.23 ORX98231.1 - 7.1e-17 61.8 0.1 1.3e-16 61.0 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 ORX98231.1 - 2.9e-14 52.9 0.0 5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORX98231.1 - 3.4e-14 53.0 0.0 5.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORX98231.1 - 0.003 17.8 0.0 0.0074 16.5 0.0 1.7 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Sel1 PF08238.12 ORX98232.1 - 2.5e-32 110.6 15.2 9.4e-08 32.5 1.9 6.8 7 0 0 7 7 7 4 Sel1 repeat TPR_16 PF13432.6 ORX98232.1 - 0.00014 22.5 3.8 1.3 9.8 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX98232.1 - 0.011 16.0 4.2 1.7 8.9 0.0 3.8 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORX98232.1 - 0.057 13.9 8.0 0.26 11.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX98232.1 - 0.068 13.0 14.3 4.3 7.3 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORX98232.1 - 0.071 13.8 11.0 9.6 7.1 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 ORX98232.1 - 0.072 12.5 5.3 0.081 12.3 3.0 2.1 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 ORX98232.1 - 0.11 12.6 3.7 1.2 9.3 0.1 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Phasin_2 PF09361.10 ORX98232.1 - 0.39 11.0 2.3 3.1 8.1 0.5 2.9 2 1 0 2 2 2 0 Phasin protein Sulfolobus_pRN PF05584.11 ORX98233.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein TPR_2 PF07719.17 ORX98234.1 - 1.1e-25 87.6 81.0 0.001 19.0 0.2 20.5 23 0 0 23 23 21 8 Tetratricopeptide repeat TPR_1 PF00515.28 ORX98234.1 - 1.3e-24 84.9 66.4 0.00067 19.4 0.2 17.9 18 0 0 18 18 18 8 Tetratricopeptide repeat TPR_19 PF14559.6 ORX98234.1 - 2.1e-22 79.4 44.6 0.00087 19.8 0.0 13.4 11 2 3 14 14 14 8 Tetratricopeptide repeat TPR_16 PF13432.6 ORX98234.1 - 7.1e-21 74.6 36.0 0.015 15.9 0.0 14.6 15 1 1 16 16 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORX98234.1 - 1.5e-18 66.1 49.4 5.2e-05 22.8 3.6 15.3 12 4 4 16 16 16 5 TPR repeat TPR_8 PF13181.6 ORX98234.1 - 7.1e-18 63.3 74.6 0.014 15.5 0.1 19.0 22 0 0 22 22 20 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORX98234.1 - 7.7e-18 63.7 30.8 0.42 11.6 0.0 16.8 13 5 6 19 19 16 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORX98234.1 - 1.8e-17 62.4 50.1 0.051 14.0 0.0 17.6 17 1 1 18 18 18 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORX98234.1 - 3e-17 62.7 51.7 0.00091 19.5 0.0 14.9 13 3 4 17 17 16 6 Tetratricopeptide repeat TPR_9 PF13371.6 ORX98234.1 - 3.1e-13 49.7 8.5 0.047 13.8 0.0 8.2 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORX98234.1 - 9.5e-08 32.2 37.3 0.86 10.4 0.0 13.3 15 0 0 15 15 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX98234.1 - 4.1e-06 26.9 46.0 0.0096 16.1 0.6 10.2 11 1 1 12 12 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORX98234.1 - 1.8e-05 24.5 20.2 1.1 9.2 0.9 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_22 PF18833.1 ORX98234.1 - 0.00031 20.8 1.5 0.0016 18.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX98234.1 - 0.00046 20.0 34.5 0.49 10.6 0.2 12.4 15 0 0 15 15 11 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORX98234.1 - 0.0081 16.1 0.4 11 5.9 0.1 3.5 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Destabilase PF05497.12 ORX98234.1 - 0.12 12.7 0.0 0.59 10.5 0.0 2.2 1 0 0 1 1 1 0 Destabilase GnsAB_toxin PF08178.11 ORX98234.1 - 0.17 11.8 0.2 0.47 10.4 0.2 1.7 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Fis1_TPR_C PF14853.6 ORX98234.1 - 0.54 10.4 0.0 0.54 10.4 0.0 5.6 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat PPTA PF01239.22 ORX98234.1 - 2.8 7.8 11.5 9.2 6.1 0.4 4.9 5 0 0 5 5 3 0 Protein prenyltransferase alpha subunit repeat Coatomer_E PF04733.14 ORX98234.1 - 7.7 5.8 16.9 0.99 8.8 0.1 4.9 6 0 0 6 6 5 0 Coatomer epsilon subunit PMT PF02366.18 ORX98235.1 - 1.8e-84 283.2 18.7 3.7e-84 282.1 18.7 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORX98235.1 - 1.2e-52 178.4 17.9 1.2e-52 178.4 17.9 2.8 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORX98235.1 - 6.2e-10 39.2 1.8 1.1e-09 38.4 1.8 1.4 1 0 0 1 1 1 1 MIR domain DUF3742 PF12553.8 ORX98235.1 - 5.7 7.1 6.3 3 8.0 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) MMM1 PF10296.9 ORX98237.1 - 6.3e-07 28.8 0.0 1.4e-06 27.6 0.0 1.5 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Abhydrolase_1 PF00561.20 ORX98238.1 - 2.6e-19 69.9 0.0 6.9e-15 55.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORX98238.1 - 5.4e-16 59.9 0.0 7.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX98238.1 - 5.9e-11 42.1 0.0 9.9e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORX98238.1 - 2.2e-09 37.4 0.0 2.2e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 ORX98238.1 - 2.8e-05 24.3 0.0 4.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 ORX98238.1 - 0.00035 20.1 0.0 0.00056 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 ORX98238.1 - 0.00098 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Esterase PF00756.20 ORX98238.1 - 0.0044 16.7 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 ORX98238.1 - 0.0067 15.8 0.0 0.14 11.5 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 ORX98238.1 - 0.027 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 ORX98238.1 - 0.044 12.9 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.7 ORX98238.1 - 0.049 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 ORX98238.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 ORX98238.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 ORX98238.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 ORX98238.1 - 0.14 11.2 0.0 16 4.5 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Palm_thioest PF02089.15 ORX98238.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase CBF PF03914.17 ORX98239.1 - 1.9e-35 122.4 0.3 1.9e-35 122.4 0.3 2.2 2 1 1 3 3 3 1 CBF/Mak21 family PEARLI-4 PF05278.12 ORX98239.1 - 0.11 12.1 2.9 0.18 11.3 2.9 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) HEAT PF02985.22 ORX98239.1 - 0.17 12.2 0.0 50 4.6 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat TACC_C PF05010.14 ORX98239.1 - 0.35 10.6 5.2 0.43 10.3 2.4 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal VASt PF16016.5 ORX98240.1 - 1.9e-41 142.0 0.1 3.9e-41 141.0 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORX98240.1 - 6.3e-23 80.8 0.1 1.7e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 GRAM domain SHR3_chaperone PF08229.11 ORX98240.1 - 1.2 8.1 3.3 0.58 9.1 0.8 1.6 1 1 1 2 2 2 0 ER membrane protein SH3 DUF2370 PF10176.9 ORX98240.1 - 5.2 6.6 6.0 1 9.0 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2370) Peptidase_S49_N PF08496.10 ORX98240.1 - 6.6 6.8 5.6 12 6.0 1.2 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MIP PF00230.20 ORX98256.1 - 1.6e-27 96.7 7.3 1.9e-27 96.4 7.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L1 PF00687.21 ORX98258.1 - 8.2e-68 228.2 5.5 1e-67 227.8 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PPS_PS PF02006.16 ORX98258.1 - 0.082 12.5 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase UPF0016 PF01169.19 ORX98259.1 - 1.4e-39 134.2 24.9 8.2e-21 74.1 6.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 G3P_acyltransf PF02660.15 ORX98259.1 - 4.8 7.2 16.1 0.082 13.0 1.7 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Mg_trans_NIPA PF05653.14 ORX98260.1 - 1.7e-110 368.8 17.1 2.1e-110 368.5 17.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORX98260.1 - 2.6e-06 27.6 7.1 2.6e-06 27.6 7.1 4.0 3 1 0 3 3 3 1 EamA-like transporter family DUF4793 PF16041.5 ORX98260.1 - 0.053 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) DUF4131 PF13567.6 ORX98260.1 - 0.061 13.0 4.7 2.8 7.6 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2937 PF11157.8 ORX98260.1 - 0.28 10.9 2.7 2.2 8.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) TIM PF00121.18 ORX98261.1 - 4.1e-95 317.8 0.4 4.6e-95 317.6 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Glyco_hydro_25 PF01183.20 ORX98261.1 - 0.057 13.6 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 25 GHL10 PF02638.15 ORX98261.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 RRM_1 PF00076.22 ORX98262.1 - 9.1e-83 272.1 8.4 1.2e-18 66.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORX98262.1 - 6.1e-10 38.8 0.3 0.01 15.4 0.1 4.5 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX98262.1 - 2.6e-06 27.2 0.0 0.3 11.0 0.0 4.8 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 ORX98262.1 - 6.6e-05 22.8 9.2 1.1 9.0 0.3 6.0 4 1 0 5 5 5 3 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 ORX98262.1 - 0.00014 21.9 0.0 0.86 9.8 0.0 4.7 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ORX98262.1 - 0.025 14.6 0.1 1.3 9.1 0.0 3.6 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif Arm-DNA-bind_4 PF14657.6 ORX98262.1 - 0.095 12.5 0.0 0.095 12.5 0.0 4.2 5 0 0 5 5 5 0 Arm DNA-binding domain Rer1 PF03248.13 ORX98263.1 - 8.3e-80 266.5 4.7 9.7e-80 266.3 4.7 1.0 1 0 0 1 1 1 1 Rer1 family FA_desaturase PF00487.24 ORX98263.1 - 0.14 12.0 3.9 2.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Fatty acid desaturase DUF2208 PF09973.9 ORX98263.1 - 1.3 8.6 7.7 0.13 11.9 2.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) WD40 PF00400.32 ORX98264.1 - 5.5e-24 84.0 15.6 0.00014 22.5 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98264.1 - 2.1e-08 34.3 7.2 0.058 13.7 0.2 4.6 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORX98264.1 - 0.00076 18.5 1.2 0.7 8.8 0.0 4.3 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L28e PF01778.17 ORX98265.1 - 2.2e-32 112.2 1.4 2.6e-32 112.0 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family CAF1 PF04857.20 ORX98266.1 - 4e-21 75.5 0.1 6.3e-10 38.7 0.0 2.5 1 1 0 2 2 2 2 CAF1 family ribonuclease zf-Tim10_DDP PF02953.15 ORX98267.1 - 5e-24 83.7 0.5 6.1e-24 83.4 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Gpi1 PF05024.15 ORX98268.1 - 4.8e-73 245.2 11.8 1e-72 244.1 11.8 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) RNA_pol_Rpb2_6 PF00562.28 ORX98269.1 - 1.6e-79 267.8 1.5 2.5e-77 260.5 1.5 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 ORX98269.1 - 2.3e-16 59.9 0.9 4.6e-16 59.0 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 ORX98269.1 - 0.0036 17.8 6.2 0.35 11.5 6.2 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 muHD PF10291.9 ORX98270.1 - 1.1e-38 133.2 0.7 2.1e-38 132.3 0.7 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 ORX98270.1 - 1.8e-17 63.4 0.7 1.8e-17 63.4 0.7 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.21 ORX98270.1 - 1.6e-08 34.3 0.2 4e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 Adaptor complexes medium subunit family zf-RING_13 PF17977.1 ORX98271.1 - 0.068 13.3 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_13 PF17977.1 ORX98272.1 - 5.2e-09 36.1 5.0 0.18 11.9 0.2 4.2 4 0 0 4 4 4 3 RING/Ubox like zinc-binding domain RPAP2_Rtr1 PF04181.13 ORX98272.1 - 0.0002 21.6 0.1 0.76 10.1 0.0 3.1 1 1 2 3 3 3 2 Rtr1/RPAP2 family Agenet PF05641.12 ORX98272.1 - 0.0098 16.3 2.0 24 5.5 0.1 3.4 3 1 0 3 3 3 1 Agenet domain WD40_alt PF14077.6 ORX98272.1 - 0.14 12.0 0.2 1.4e+02 2.4 0.0 3.8 4 0 0 4 4 4 0 Alternative WD40 repeat motif Hemerythrin PF01814.23 ORX98272.1 - 0.16 12.6 0.2 7.5 7.2 0.1 2.8 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Rtf2 PF04641.12 ORX98272.1 - 0.22 10.9 1.0 16 4.7 0.5 3.4 2 1 0 2 2 2 0 Rtf2 RING-finger CarbpepA_inh PF02977.15 ORX98272.1 - 6.4 6.7 13.1 32 4.4 0.0 4.1 3 1 0 3 3 3 0 Carboxypeptidase A inhibitor zf-RING_13 PF17977.1 ORX98273.1 - 7.9e-05 22.7 0.5 0.53 10.5 0.1 2.3 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain Agenet PF05641.12 ORX98273.1 - 0.074 13.5 0.0 16 6.0 0.0 2.2 2 0 0 2 2 2 0 Agenet domain DUF4148 PF13663.6 ORX98274.1 - 0.95 9.7 4.2 16 5.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Ureidogly_lyase PF04115.12 ORX98275.1 - 8.4e-49 165.9 0.0 9.6e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Ribosomal_S3Ae PF01015.18 ORX98276.1 - 4.4e-49 166.8 0.7 5.5e-49 166.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 ORX98276.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region WD40 PF00400.32 ORX98277.1 - 9.4e-41 137.0 15.9 7.4e-08 32.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98277.1 - 2.8e-17 62.8 0.0 0.00055 20.2 0.1 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX98277.1 - 0.00015 21.8 0.0 0.091 12.6 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORX98277.1 - 0.00033 20.1 0.0 0.025 13.9 0.0 3.1 2 1 2 4 4 4 1 WD40-like domain Nup160 PF11715.8 ORX98277.1 - 0.017 13.8 0.1 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ret2_MD PF18528.1 ORX98277.1 - 0.11 12.9 0.0 26 5.3 0.0 3.1 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Cytochrom_D1 PF02239.16 ORX98277.1 - 0.12 10.9 0.0 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain NIF PF03031.18 ORX98278.1 - 1.1e-25 90.2 0.7 6.2e-25 87.8 0.2 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 ORX98278.1 - 3.7e-09 36.4 0.1 7.6e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORX98278.1 - 9.7e-07 29.1 0.0 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORX98278.1 - 0.0073 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ORX98278.1 - 0.045 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DNA_pol_phi PF04931.13 ORX98278.1 - 7.3 4.6 9.7 14 3.6 9.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi MRG PF05712.13 ORX98279.1 - 7.1e-46 156.0 0.3 1.1e-45 155.4 0.3 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 ORX98279.1 - 2.2e-09 37.0 0.3 5.1e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 ORX98279.1 - 0.014 15.3 0.6 0.036 14.0 0.6 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ETF PF01012.21 ORX98281.1 - 1.8e-42 145.3 5.6 2.8e-42 144.7 5.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 ORX98281.1 - 1.3e-34 118.0 0.2 2.8e-34 117.0 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Mucin PF01456.17 ORX98282.1 - 0.1 12.6 40.3 0.35 10.9 17.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein GPI-anchored PF10342.9 ORX98283.1 - 0.0048 17.6 0.0 0.023 15.4 0.0 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MIP PF00230.20 ORX98287.1 - 1.5e-29 103.3 11.3 1.8e-29 103.0 11.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein RRM_1 PF00076.22 ORX98319.1 - 6.1e-22 77.2 0.3 6.9e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX98319.1 - 3.2e-06 26.9 0.2 0.0023 17.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF1027 PF06265.11 ORX98319.1 - 0.0069 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1027) PHM7_cyt PF14703.6 ORX98319.1 - 0.039 14.2 1.6 8.8 6.5 0.4 2.7 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 ORX98319.1 - 0.045 13.9 0.1 9.2 6.5 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif MMR_HSR1_C PF08438.10 ORX98319.1 - 0.12 13.0 1.1 7.8 7.1 1.1 2.4 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Rap_GAP PF02145.15 ORX98320.1 - 8.1e-62 208.1 0.0 1.3e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP HMGL-like PF00682.19 ORX98321.1 - 3.9e-79 265.9 0.2 5.5e-79 265.4 0.2 1.2 1 0 0 1 1 1 1 HMGL-like DUF3666 PF12408.8 ORX98321.1 - 0.074 12.3 0.2 0.29 10.4 0.2 1.9 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Bac_globin PF01152.21 ORX98322.1 - 4e-08 33.4 0.2 4.9e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 Bacterial-like globin MFS_1 PF07690.16 ORX98323.1 - 1e-25 90.4 21.4 1e-25 90.4 21.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S14 PF00253.21 ORX98324.1 - 3.2e-21 74.8 1.1 3.2e-21 74.8 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Ion_trans PF00520.31 ORX98325.1 - 5.5e-28 97.8 18.1 7.7e-28 97.4 18.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 ORX98325.1 - 3.8e-14 52.4 5.4 3.8e-14 52.4 5.4 2.5 3 1 0 3 3 3 1 Ion channel DUF2937 PF11157.8 ORX98325.1 - 0.72 9.6 3.1 21 4.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DEAD PF00270.29 ORX98326.1 - 2e-47 161.2 0.4 4.9e-47 159.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX98326.1 - 1.5e-24 86.5 0.0 1.1e-23 83.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORX98326.1 - 3.1e-20 72.1 0.0 7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORX98326.1 - 3.2e-07 30.5 0.0 3.2e-07 30.5 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit BSP_II PF05432.11 ORX98326.1 - 2.3 7.8 27.6 0.071 12.8 6.5 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pyr_redox_2 PF07992.14 ORX98327.1 - 2.8e-68 230.3 7.7 3.9e-68 229.8 6.9 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORX98327.1 - 1.2e-42 144.7 0.1 9.7e-42 141.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORX98327.1 - 1e-21 77.2 11.7 5.1e-19 68.6 2.1 4.1 4 1 1 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORX98327.1 - 2.4e-12 46.9 11.2 2.3e-11 43.7 0.2 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX98327.1 - 5.9e-11 42.2 6.1 7.7e-08 31.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORX98327.1 - 1.9e-09 37.6 2.0 4.5e-05 23.6 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORX98327.1 - 7.8e-09 35.1 10.0 6.6e-08 32.0 3.7 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ORX98327.1 - 3e-08 33.2 4.2 3.5e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 ORX98327.1 - 1.7e-07 30.7 2.2 1.7e-07 30.7 2.2 4.0 4 1 1 5 5 5 1 FAD binding domain HI0933_like PF03486.14 ORX98327.1 - 6.7e-07 28.4 15.1 9.2e-05 21.3 1.2 4.1 2 1 2 4 4 4 3 HI0933-like protein K_oxygenase PF13434.6 ORX98327.1 - 1.3e-06 27.8 0.3 0.012 14.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ORX98327.1 - 2.4e-06 27.0 10.5 0.00055 19.3 0.6 3.6 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORX98327.1 - 0.0042 16.4 13.5 0.014 14.7 1.0 3.5 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.24 ORX98327.1 - 0.08 12.5 20.6 0.62 9.6 0.2 3.7 2 2 1 4 4 4 0 FAD dependent oxidoreductase Lipoprotein_17 PF04200.12 ORX98327.1 - 0.55 10.6 7.7 0.44 10.9 0.3 2.9 3 0 0 3 3 3 0 Lipoprotein associated domain NAD_binding_7 PF13241.6 ORX98327.1 - 1.4 9.4 4.3 13 6.3 0.7 3.0 3 1 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ORX98327.1 - 2.4 8.0 7.3 0.24 11.3 1.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORX98327.1 - 4.8 6.1 8.8 0.64 9.0 0.7 2.8 3 1 0 3 3 3 0 Lycopene cyclase protein E1_dh PF00676.20 ORX98328.1 - 1.9e-117 391.5 0.1 2.2e-117 391.3 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORX98328.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 ORX98328.1 - 0.029 15.3 2.6 5.5 8.0 0.1 3.0 2 1 0 2 2 2 0 KRTAP type 7 family Peptidase_M16 PF00675.20 ORX98329.1 - 3e-45 153.8 0.2 6.8e-45 152.7 0.2 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORX98329.1 - 5.3e-36 124.3 0.0 8.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain CybS PF05328.12 ORX98330.1 - 1e-38 132.0 0.1 1.3e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit GPI-anchored PF10342.9 ORX98331.1 - 5.5e-14 52.7 0.2 7.5e-14 52.3 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MGC-24 PF05283.11 ORX98332.1 - 0.1 13.1 3.5 0.13 12.7 3.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF726 PF05277.12 ORX98333.1 - 1.2e-106 356.5 0.1 1.6e-106 356.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MerE PF05052.12 ORX98333.1 - 0.0098 15.8 2.9 0.51 10.3 0.9 2.8 2 1 0 2 2 2 2 MerE protein Abhydrolase_6 PF12697.7 ORX98333.1 - 0.033 14.8 1.1 0.092 13.3 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ORX98333.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain RasGEF PF00617.19 ORX98334.1 - 5.4e-50 170.0 2.4 8.2e-50 169.4 2.4 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORX98334.1 - 1.3e-20 73.5 1.7 2.3e-20 72.8 0.4 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Helicase_C_2 PF13307.6 ORX98335.1 - 8.2e-58 195.4 0.1 2e-56 190.8 0.0 2.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORX98335.1 - 6.7e-51 172.4 1.0 1.3e-50 171.5 1.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ORX98335.1 - 5.9e-05 23.1 1.2 0.17 11.9 0.1 3.3 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit PhoH PF02562.16 ORX98335.1 - 0.02 14.4 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 ORX98335.1 - 0.084 13.2 3.2 1.6 9.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain Auts2 PF15336.6 ORX98335.1 - 3.9 7.6 9.8 7.4 6.6 9.8 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein CUE PF02845.16 ORX98336.1 - 6.8e-11 41.6 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 ORX98336.1 - 1.9e-05 24.2 5.1 1.9e-05 24.2 5.1 1.7 2 0 0 2 2 2 1 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 ORX98336.1 - 0.081 13.0 2.0 0.19 11.8 2.0 1.7 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 Rep_fac-A_C PF08646.10 ORX98337.1 - 0.004 16.9 0.5 0.0055 16.5 0.5 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain zinc_ribbon_4 PF13717.6 ORX98337.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 ORX98337.1 - 0.073 12.9 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RasGEF PF00617.19 ORX98338.1 - 3.9e-39 134.7 0.0 8.4e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain HA2 PF04408.23 ORX98339.1 - 1.9e-24 86.0 0.0 5.2e-24 84.6 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORX98339.1 - 6.2e-11 42.6 0.0 1.7e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORX98339.1 - 2.1e-09 37.4 0.1 4.7e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORX98339.1 - 1e-05 25.9 0.2 2.3e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 ORX98339.1 - 0.00038 20.4 0.1 0.00088 19.3 0.1 1.6 1 1 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.6 ORX98339.1 - 0.00041 20.6 0.2 0.0022 18.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORX98339.1 - 0.00085 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ORX98339.1 - 0.0017 18.0 0.8 0.018 14.7 0.8 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 ORX98339.1 - 0.0023 18.0 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORX98339.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 ORX98339.1 - 0.0082 15.6 0.4 0.023 14.2 0.1 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_23 PF13476.6 ORX98339.1 - 0.013 16.0 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORX98339.1 - 0.034 13.9 0.1 8.6 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORX98339.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 ORX98339.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 ORX98339.1 - 0.09 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.27 ORX98339.1 - 0.1 13.1 0.1 0.3 11.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 ORX98339.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain LRR_4 PF12799.7 ORX98340.1 - 0.0036 17.7 0.5 0.8 10.2 0.0 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) TMEM100 PF16311.5 ORX98341.1 - 0.2 11.2 0.9 0.29 10.7 0.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 DUF997 PF06196.12 ORX98341.1 - 2 8.5 6.2 2.8 8.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) F-box-like PF12937.7 ORX98342.1 - 0.01 15.7 0.3 0.14 12.1 0.0 2.7 2 0 0 2 2 2 0 F-box-like DUF3433 PF11915.8 ORX98342.1 - 0.033 14.6 0.1 0.062 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Polysacc_deac_1 PF01522.21 ORX98343.1 - 3.8e-30 104.3 0.0 1e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase COX16 PF14138.6 ORX98344.1 - 4.3e-27 94.4 0.1 5.6e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Myb_DNA-bind_3 PF12776.7 ORX98344.1 - 0.016 16.1 0.3 0.026 15.5 0.3 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Arrestin_C PF02752.22 ORX98345.1 - 9.8e-14 51.9 0.1 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX98345.1 - 2.1e-09 37.6 0.2 8.5e-09 35.6 0.1 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX98345.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Glyco_transf_8C PF08437.10 ORX98349.1 - 0.11 12.6 0.8 0.11 12.6 0.8 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal Ten1 PF12658.7 ORX98350.1 - 0.17 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit Myticin-prepro PF10690.9 ORX98351.1 - 0.0038 17.4 0.3 0.0059 16.8 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Squash PF00299.18 ORX98356.1 - 0.038 14.0 1.4 0.038 14.0 1.4 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor DJ-1_PfpI PF01965.24 ORX98357.1 - 7.3e-09 35.6 0.0 2.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORX98357.1 - 0.0016 18.2 0.1 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORX98357.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Latrotoxin C-terminal domain CBM_5_12 PF02839.14 ORX98378.1 - 4.2e-06 27.0 10.4 4.2e-06 27.0 10.4 2.1 2 1 1 3 3 3 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORX98378.1 - 0.0086 16.0 5.9 0.012 15.6 5.9 1.4 1 1 0 1 1 1 1 Cellulose-binding domain Glyco_hydro_18 PF00704.28 ORX98379.1 - 6.4e-54 183.8 0.1 7.5e-54 183.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipocalin_2 PF08212.12 ORX98380.1 - 3.6e-29 101.6 0.1 4.7e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 ORX98380.1 - 1.1e-07 32.1 0.5 1.9e-07 31.4 0.5 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family AgrD PF05931.11 ORX98380.1 - 0.41 10.7 1.8 0.54 10.3 0.1 2.1 3 0 0 3 3 3 0 Staphylococcal AgrD protein FGE-sulfatase PF03781.16 ORX98381.1 - 1.3e-48 165.9 0.3 1.8e-48 165.4 0.3 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Wzt_C PF14524.6 ORX98382.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 1 0 1 1 1 0 Wzt C-terminal domain GPI-anchored PF10342.9 ORX98382.1 - 0.1 13.4 0.1 0.24 12.2 0.1 1.8 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_S8 PF00082.22 ORX98383.1 - 7.7e-37 127.2 18.3 2.3e-36 125.6 18.3 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98383.1 - 1.3e-07 32.1 0.1 2.5e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 ORX98384.1 - 5.4e-37 127.7 18.4 1.5e-36 126.2 18.4 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98384.1 - 1.3e-07 32.1 0.1 2.5e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 ORX98385.1 - 5.1e-36 124.5 19.0 1.4e-35 123.0 19.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98385.1 - 1.1e-06 29.1 0.2 2.4e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98385.1 - 0.019 15.0 0.3 0.036 14.1 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98386.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98386.1 - 2.4e-07 31.3 0.2 5e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98386.1 - 0.012 15.7 0.4 0.021 14.9 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98387.1 - 3.7e-36 124.9 18.9 1e-35 123.4 18.9 1.6 1 1 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 ORX98388.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98388.1 - 4.5e-07 30.4 0.2 9.4e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98388.1 - 0.034 14.2 0.5 0.064 13.3 0.5 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98389.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98389.1 - 2.4e-07 31.3 0.2 5e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98389.1 - 0.012 15.7 0.4 0.021 14.9 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98390.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98390.1 - 2.7e-07 31.2 0.2 5e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98390.1 - 0.0088 16.1 0.4 0.015 15.3 0.4 1.4 1 0 0 1 1 1 1 DivIVA protein Peptidase_S8 PF00082.22 ORX98391.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98391.1 - 2.4e-07 31.3 0.2 5e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98391.1 - 0.012 15.7 0.4 0.021 14.9 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98392.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98392.1 - 6.7e-07 29.9 0.2 1.4e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98392.1 - 0.04 14.0 0.4 0.073 13.2 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98393.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98393.1 - 2.4e-07 31.3 0.2 5e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98393.1 - 0.012 15.7 0.4 0.021 14.9 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein Peptidase_S8 PF00082.22 ORX98394.1 - 5e-36 124.5 19.0 1.4e-35 123.0 19.0 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX98394.1 - 1.5e-07 32.0 0.2 3.1e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DivIVA PF05103.13 ORX98394.1 - 0.0094 16.0 0.4 0.017 15.2 0.4 1.4 1 0 0 1 1 1 1 DivIVA protein HMA PF00403.26 ORX98395.1 - 2.2e-14 53.7 0.9 2.4e-14 53.5 0.9 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain NapD PF03927.13 ORX98395.1 - 0.00055 19.9 0.1 0.00065 19.7 0.1 1.0 1 0 0 1 1 1 1 NapD protein MAPEG PF01124.18 ORX98396.1 - 2.3e-17 63.1 3.8 2.6e-17 63.0 3.8 1.0 1 0 0 1 1 1 1 MAPEG family Glyco_hydro_46 PF01374.18 ORX98397.1 - 0.00015 21.4 0.1 0.00018 21.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Lipase_3 PF01764.25 ORX98398.1 - 4.8e-24 84.8 0.0 7.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX98398.1 - 0.032 14.8 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.22 ORX98399.1 - 8.4e-60 201.0 0.2 9.7e-60 200.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX98399.1 - 9.4e-20 71.0 0.0 1.4e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX98399.1 - 1.7e-09 37.4 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORX98399.1 - 2.3e-05 24.4 0.0 0.036 14.0 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORX98399.1 - 6.2e-05 22.6 0.1 0.00015 21.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ORX98399.1 - 0.00039 20.4 0.1 0.00085 19.3 0.1 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORX98399.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX98399.1 - 0.0059 16.2 0.1 0.015 14.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B CENP-M PF11111.8 ORX98399.1 - 0.17 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) CbiA PF01656.23 ORX98399.1 - 0.24 11.4 1.2 2.5 8.2 1.2 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ORX98399.1 - 0.46 10.2 2.8 2.3 8.0 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Cytochrom_C PF00034.21 ORX98400.1 - 7.5e-12 46.2 0.1 1.1e-11 45.7 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORX98400.1 - 3.6e-08 33.6 2.1 1.4e-07 31.7 2.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORX98400.1 - 0.002 17.8 1.8 0.016 14.9 1.7 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 ORX98400.1 - 0.017 15.8 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 ORX98400.1 - 0.058 13.0 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Polysacc_deac_1 PF01522.21 ORX98401.1 - 3.3e-30 104.5 0.0 4.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ferrochelatase PF00762.19 ORX98401.1 - 0.048 12.7 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrochelatase DSPc PF00782.20 ORX98402.1 - 6.6e-27 93.9 0.0 8.4e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TOM20_plant PF06552.12 ORX98402.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Endotoxin_C PF03944.14 ORX98402.1 - 0.13 12.6 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 delta endotoxin Aminotran_5 PF00266.19 ORX98406.1 - 2.1e-28 99.3 0.0 2.7e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORX98406.1 - 7.3e-05 22.1 0.0 0.0001 21.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORX98406.1 - 0.0037 16.6 0.0 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ald_deCOase PF11266.8 ORX98406.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase Polysacc_deac_1 PF01522.21 ORX98407.1 - 2.8e-28 98.3 0.0 4.7e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase TACC_C PF05010.14 ORX98409.1 - 1.8e-05 24.7 5.7 1.8e-05 24.7 5.7 2.2 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 ORX98409.1 - 3.9e-05 23.1 19.5 0.0046 16.3 5.5 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ORX98409.1 - 0.0035 16.3 16.9 0.0053 15.7 16.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 ORX98409.1 - 0.008 15.8 9.2 0.012 15.2 9.2 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Tropomyosin PF00261.20 ORX98409.1 - 0.011 15.1 17.5 0.015 14.7 17.5 1.1 1 0 0 1 1 1 0 Tropomyosin bZIP_1 PF00170.21 ORX98409.1 - 0.012 15.7 10.6 0.014 15.5 2.2 2.9 2 1 1 3 3 2 0 bZIP transcription factor DUF1216 PF06746.11 ORX98409.1 - 0.015 15.3 1.7 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) TMF_TATA_bd PF12325.8 ORX98409.1 - 0.02 15.1 18.9 0.27 11.5 5.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PH_18 PF18469.1 ORX98409.1 - 0.04 13.9 1.0 0.066 13.2 0.8 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain Sec2p PF06428.11 ORX98409.1 - 0.042 13.8 21.1 0.065 13.2 8.3 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p TMCO5 PF14992.6 ORX98409.1 - 0.057 13.0 20.6 0.036 13.6 17.0 1.9 1 1 1 2 2 2 0 TMCO5 family Rootletin PF15035.6 ORX98409.1 - 0.062 13.3 23.3 0.13 12.2 23.3 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 ORX98409.1 - 0.064 13.5 14.4 0.12 12.5 13.3 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.6 ORX98409.1 - 0.087 12.6 18.7 0.22 11.3 6.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 ORX98409.1 - 0.098 12.7 23.7 0.073 13.1 7.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ax_dynein_light PF10211.9 ORX98409.1 - 0.11 12.5 20.7 0.47 10.4 9.1 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4618 PF15397.6 ORX98409.1 - 0.11 11.9 18.2 0.068 12.6 10.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 ORX98409.1 - 0.12 12.8 12.7 0.12 12.8 2.6 4.3 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 ORX98409.1 - 0.13 12.5 24.9 0.2 11.9 18.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 ORX98409.1 - 0.15 11.4 21.4 0.032 13.5 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Macoilin PF09726.9 ORX98409.1 - 0.15 10.6 16.8 0.24 9.9 16.8 1.2 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 ORX98409.1 - 0.15 12.5 20.0 1 9.8 18.6 1.9 1 1 1 2 2 2 0 Fez1 DUF724 PF05266.14 ORX98409.1 - 0.16 11.8 18.2 0.22 11.3 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 ORX98409.1 - 0.16 11.6 21.8 0.34 10.5 21.7 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AcylCoA_dehyd_C PF12186.8 ORX98409.1 - 0.17 12.0 5.3 1.5 9.0 0.3 2.3 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal TF_AP-2 PF03299.14 ORX98409.1 - 0.18 11.8 8.1 1 9.3 0.8 2.1 1 1 1 2 2 2 0 Transcription factor AP-2 She9_MDM33 PF05546.11 ORX98409.1 - 0.22 11.3 13.4 0.36 10.6 13.4 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family KASH_CCD PF14662.6 ORX98409.1 - 0.22 11.3 20.0 0.3 10.9 20.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SICA_alpha PF12887.7 ORX98409.1 - 0.23 11.3 9.3 0.08 12.8 5.5 1.9 1 1 1 2 2 2 0 SICA extracellular alpha domain APG6_N PF17675.1 ORX98409.1 - 0.24 11.9 29.8 0.81 10.2 13.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region MAD PF05557.13 ORX98409.1 - 0.24 9.7 23.3 0.31 9.4 21.6 1.7 1 1 1 2 2 2 0 Mitotic checkpoint protein CALCOCO1 PF07888.11 ORX98409.1 - 0.24 10.2 23.0 0.68 8.7 4.8 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.8 ORX98409.1 - 0.31 11.0 24.6 2.1 8.4 7.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Tn7_Tnp_TnsA_C PF08721.11 ORX98409.1 - 0.47 11.1 9.0 0.53 11.0 0.5 3.1 2 1 1 3 3 3 0 TnsA endonuclease C terminal ADIP PF11559.8 ORX98409.1 - 0.5 10.4 24.1 8.5 6.4 8.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 ORX98409.1 - 0.51 10.4 10.8 2 8.5 1.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 ORX98409.1 - 0.55 10.2 13.4 0.46 10.5 2.1 2.5 1 1 2 3 3 3 0 Laminin Domain II CtIP_N PF10482.9 ORX98409.1 - 0.69 10.0 18.0 0.9 9.6 16.0 1.9 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ERM PF00769.19 ORX98409.1 - 0.72 9.6 22.4 2.4 7.9 21.2 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 ORX98409.1 - 0.82 7.1 18.5 1.2 6.6 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 ORX98409.1 - 0.85 9.8 22.8 3.9 7.6 22.8 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 ORX98409.1 - 0.94 9.6 24.8 0.8 9.8 9.4 2.3 1 1 1 2 2 2 0 Tropomyosin like ZapB PF06005.12 ORX98409.1 - 1 9.8 23.4 1.1 9.8 6.1 2.9 1 1 1 3 3 2 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 ORX98409.1 - 1 9.9 13.8 16 6.1 11.2 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tox-SHH PF15652.6 ORX98409.1 - 1.1 10.3 4.3 1.4 9.9 0.3 2.4 1 1 1 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature GrpE PF01025.19 ORX98409.1 - 1.1 9.0 20.5 2.4 7.8 10.9 2.9 1 1 2 3 3 3 0 GrpE KLRAQ PF10205.9 ORX98409.1 - 1.1 9.5 18.9 2.8 8.3 4.7 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF641 PF04859.12 ORX98409.1 - 1.1 9.6 14.5 3.1 8.1 0.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 ORX98409.1 - 1.2 9.2 26.1 2.8 8.0 7.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2203 PF09969.9 ORX98409.1 - 1.6 9.5 12.5 7.4 7.3 3.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ORF6C PF10552.9 ORX98409.1 - 1.6 8.8 9.5 0.2 11.8 0.5 2.6 2 1 0 2 2 2 0 ORF6C domain DUF4407 PF14362.6 ORX98409.1 - 1.7 8.0 13.3 2.5 7.4 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 ORX98409.1 - 2.1 8.2 21.3 0.11 12.3 4.1 3.3 1 1 2 3 3 3 0 Septum formation initiator BRE1 PF08647.11 ORX98409.1 - 2.2 8.4 19.8 0.51 10.4 9.2 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 ORX98409.1 - 2.4 8.4 18.0 3.3 8.0 6.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.13 ORX98409.1 - 2.4 8.3 23.6 7.9 6.6 22.5 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LMBR1 PF04791.16 ORX98409.1 - 2.4 6.9 8.9 3 6.7 8.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein HAUS6_N PF14661.6 ORX98409.1 - 2.6 7.6 17.7 3.3 7.2 7.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Prominin PF05478.11 ORX98409.1 - 2.9 5.7 9.3 4.2 5.2 9.3 1.2 1 0 0 1 1 1 0 Prominin YabA PF06156.13 ORX98409.1 - 3.4 8.3 16.0 8.3 7.1 5.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 ORX98409.1 - 4.7 6.0 20.6 4.2 6.1 5.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) THOC7 PF05615.13 ORX98409.1 - 5.1 7.4 20.5 4.9 7.4 10.5 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 BLOC1_2 PF10046.9 ORX98409.1 - 5.2 7.4 14.4 7.1 7.0 3.8 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 ORX98409.1 - 5.4 7.0 10.2 1.7 8.5 0.3 4.0 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EzrA PF06160.12 ORX98409.1 - 6.2 4.9 20.0 4 5.5 10.4 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA tRNA-synt_His PF13393.6 ORX98409.1 - 6.4 6.0 10.9 3.2 7.0 6.2 1.9 1 1 1 2 2 2 0 Histidyl-tRNA synthetase V_ATPase_I PF01496.19 ORX98409.1 - 8.3 4.2 14.2 18 3.1 14.2 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family NEMO PF11577.8 ORX98409.1 - 8.7 6.4 15.8 1.6 8.8 3.3 2.7 2 1 1 3 3 2 0 NF-kappa-B essential modulator NEMO HIP1_clath_bdg PF16515.5 ORX98409.1 - 9.2 7.0 24.6 0.18 12.4 4.8 2.7 1 1 2 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 ORX98409.1 - 9.4 5.2 20.0 7.1 5.6 12.4 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Voldacs PF03517.13 ORX98410.1 - 1e-18 67.8 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Fasciclin PF02469.22 ORX98411.1 - 4.1e-15 56.1 0.5 4.9e-15 55.9 0.5 1.1 1 0 0 1 1 1 1 Fasciclin domain Type_ISP_C PF18135.1 ORX98411.1 - 0.039 13.0 0.0 0.044 12.8 0.0 1.0 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain Arrestin_C PF02752.22 ORX98412.1 - 3.1e-11 43.9 0.0 4.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX98412.1 - 4.9e-09 36.4 0.0 2.6e-08 34.0 0.0 2.2 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORX98412.1 - 0.012 15.4 0.0 0.13 11.9 0.0 2.5 2 1 1 3 3 3 0 Arrestin_N terminal like Arrestin_N PF00339.29 ORX98413.1 - 1.2e-05 25.4 0.0 7.1e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX98413.1 - 2e-05 25.1 0.0 4.7e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX98413.1 - 0.0066 16.2 0.0 0.18 11.5 0.0 2.5 2 1 0 3 3 3 1 Arrestin_N terminal like Polysacc_deac_1 PF01522.21 ORX98414.1 - 5.1e-29 100.7 0.0 7.4e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORX98414.1 - 0.0034 16.6 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 ORX98415.1 - 1.2e-27 96.3 0.0 2.3e-27 95.4 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase Scaffolding_pro PF11418.8 ORX98415.1 - 0.1 13.2 0.0 0.35 11.5 0.0 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein Lipocalin_2 PF08212.12 ORX98416.1 - 3.6e-29 101.6 0.1 4.7e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 ORX98416.1 - 1.1e-07 32.1 0.5 1.9e-07 31.4 0.5 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family AgrD PF05931.11 ORX98416.1 - 0.41 10.7 1.8 0.54 10.3 0.1 2.1 3 0 0 3 3 3 0 Staphylococcal AgrD protein Glyco_hydro_18 PF00704.28 ORX98417.1 - 4.4e-54 184.3 0.1 5.2e-54 184.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 ORX98454.1 - 5.8e-15 55.1 21.9 7.6e-15 54.7 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX98454.1 - 7.3e-14 51.8 8.9 7.3e-14 51.8 8.9 2.0 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX98454.1 - 0.035 13.0 8.3 0.014 14.2 5.7 1.6 1 1 0 1 1 1 0 MFS_1 like family PUCC PF03209.15 ORX98454.1 - 0.042 12.8 12.0 0.042 12.8 9.6 2.1 2 1 0 2 2 2 0 PUCC protein CPP1-like PF11833.8 ORX98454.1 - 3.8 7.1 6.1 0.85 9.2 2.0 2.0 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Glyco_hydro_18 PF00704.28 ORX98455.1 - 3.8e-10 40.0 0.0 6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORX98455.1 - 0.1 13.2 1.6 0.1 13.2 1.6 2.9 3 1 0 3 3 3 0 Carbohydrate binding domain Amidohydro_1 PF01979.20 ORX98456.1 - 2.3e-70 237.6 1.4 3.4e-70 237.0 1.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORX98456.1 - 1.1e-56 190.3 2.5 2.6e-56 189.2 2.5 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 ORX98456.1 - 1.3e-39 134.5 0.2 3e-39 133.3 0.2 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 ORX98456.1 - 2.3e-38 130.2 0.0 4.7e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 ORX98456.1 - 2.2e-06 27.4 0.1 1.4e-05 24.8 0.0 2.2 2 1 0 3 3 3 1 Amidohydrolase family Amidohydro_2 PF04909.14 ORX98456.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Abhydrolase_3 PF07859.13 ORX98457.1 - 8.4e-39 133.6 0.0 1.2e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX98457.1 - 4.6e-13 48.8 0.0 6.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORX98457.1 - 0.0025 17.3 0.0 0.0067 15.9 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 ORX98457.1 - 0.045 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 ORX98457.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SURF4 PF02077.15 ORX98458.1 - 3.9e-91 305.4 5.9 4.4e-91 305.2 5.9 1.0 1 0 0 1 1 1 1 SURF4 family PAP_central PF04928.17 ORX98458.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain HR_lesion PF05514.11 ORX98458.1 - 1.9 8.7 11.6 0.21 11.7 3.8 2.7 2 1 1 3 3 3 0 HR-like lesion-inducing SURF4 PF02077.15 ORX98459.1 - 7.2e-90 301.2 6.3 8.1e-90 301.0 6.3 1.0 1 0 0 1 1 1 1 SURF4 family PAP_central PF04928.17 ORX98459.1 - 0.22 10.5 0.1 0.33 9.9 0.1 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain HR_lesion PF05514.11 ORX98459.1 - 1.9 8.7 11.6 0.21 11.7 3.8 2.7 2 1 1 3 3 3 0 HR-like lesion-inducing Aminotran_1_2 PF00155.21 ORX98460.1 - 4.3e-47 161.1 0.0 5.4e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORX98460.1 - 4.8e-08 31.9 0.0 8.9e-08 31.0 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ORX98460.1 - 0.041 13.2 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORX98460.1 - 0.053 12.2 0.0 0.89 8.2 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Sin_N PF04801.13 ORX98461.1 - 1.1e-53 183.0 4.2 1.3e-53 182.8 4.2 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region G-alpha PF00503.20 ORX98462.1 - 2.4e-118 395.4 0.9 2.8e-118 395.1 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX98462.1 - 6.4e-15 55.0 2.0 2.9e-10 39.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX98462.1 - 0.00086 18.7 4.3 0.016 14.6 0.1 2.8 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region MCM PF00493.23 ORX98462.1 - 0.00094 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain KIND PF16474.5 ORX98462.1 - 0.0059 16.5 0.2 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain zf-CHC2 PF01807.20 ORX98462.1 - 0.014 15.2 0.0 0.058 13.2 0.0 2.0 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 ORX98462.1 - 0.019 14.7 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORX98462.1 - 0.036 14.3 0.2 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORX98462.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 ORX98462.1 - 0.14 11.7 1.5 5.8 6.4 0.1 2.7 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX98462.1 - 0.15 12.2 0.2 9.1 6.4 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase PHD20L1_u1 PF16660.5 ORX98463.1 - 0.19 12.5 4.2 4.8 8.0 0.1 3.4 3 0 0 3 3 3 0 PHD finger protein 20-like protein 1 SIR2 PF02146.17 ORX98465.1 - 4.5e-52 176.5 0.0 7.6e-52 175.8 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Med27 PF11571.8 ORX98465.1 - 0.034 14.5 0.4 0.6 10.5 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 27 Cytochrom_C PF00034.21 ORX98465.1 - 0.1 13.8 0.0 0.39 11.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c Glyco_transf_28 PF03033.20 ORX98465.1 - 0.17 12.0 0.1 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Ribosomal_L5e PF17144.4 ORX98467.1 - 1.3e-86 288.6 0.3 1.3e-86 288.6 0.3 2.6 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORX98467.1 - 1.3e-31 109.4 8.9 1.3e-31 109.4 8.9 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Sel1 PF08238.12 ORX98468.1 - 1.3e-24 86.1 3.9 9.7e-08 32.4 0.0 4.2 4 0 0 4 4 4 4 Sel1 repeat MINDY_DUB PF04424.13 ORX98468.1 - 0.068 13.2 0.1 7.3 6.6 0.0 2.4 1 1 1 2 2 2 0 MINDY deubiquitinase Ferritin PF00210.24 ORX98469.1 - 5.6e-21 75.0 0.0 6.2e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Ferritin PF00210.24 ORX98470.1 - 8.5e-41 139.2 0.3 9.8e-41 139.0 0.3 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ORX98470.1 - 2.4e-07 31.2 0.1 3.1e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Rubrerythrin FCH PF00611.23 ORX98470.1 - 0.11 12.8 0.3 0.21 11.9 0.3 1.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.27 ORX98471.1 - 5.1e-35 120.5 0.1 6.6e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_46 PF01374.18 ORX98472.1 - 2.6e-32 112.2 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 PX PF00787.24 ORX98474.1 - 9.8e-07 28.8 0.1 3.4e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 ORX98474.1 - 9.9e-07 28.6 0.6 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 PB1 domain TMEM190 PF15431.6 ORX98475.1 - 0.00078 19.6 0.6 0.00078 19.6 0.6 1.9 2 0 0 2 2 2 1 Transmembrane protein 190 DUF4381 PF14316.6 ORX98475.1 - 0.0013 19.0 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) LapA_dom PF06305.11 ORX98475.1 - 0.014 15.2 1.3 0.018 14.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF443 PF04276.12 ORX98475.1 - 0.029 14.2 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF5305 PF17231.2 ORX98475.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Stevor PF17410.2 ORX98475.1 - 0.11 12.0 1.5 0.15 11.6 1.4 1.4 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 ORX98475.1 - 0.12 13.3 0.1 0.3 12.0 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PX PF00787.24 ORX98476.1 - 0.0057 16.6 0.2 0.015 15.2 0.2 1.7 1 1 0 1 1 1 1 PX domain PB1 PF00564.24 ORX98476.1 - 0.0097 15.8 0.3 0.023 14.6 0.3 1.6 1 1 0 1 1 1 1 PB1 domain Rhodanese PF00581.20 ORX98477.1 - 4.2e-27 94.8 0.0 5.5e-13 49.4 0.0 2.5 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 ORX98477.1 - 0.097 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 ThiC-associated domain Reo_sigmaC PF04582.12 ORX98477.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain NUDIX PF00293.28 ORX98478.1 - 8.8e-12 45.2 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AhpC-TSA PF00578.21 ORX98479.1 - 6.2e-35 119.8 0.0 8.3e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX98479.1 - 1.6e-14 53.9 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORX98479.1 - 1.8e-12 46.9 0.0 4.3e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ribosomal_60s PF00428.19 ORX98480.1 - 4.9e-26 91.1 13.4 5.6e-26 91.0 13.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein MT PF12777.7 ORX98480.1 - 0.05 12.6 1.3 0.057 12.4 1.3 1.0 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Exo_endo_phos PF03372.23 ORX98481.1 - 7.5e-10 38.7 0.0 3.1e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nop16 PF09420.10 ORX98482.1 - 2.6e-57 194.3 6.1 3.2e-57 194.0 6.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 CENP-B_dimeris PF09026.10 ORX98483.1 - 0.25 11.7 9.5 0.69 10.3 9.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORX98483.1 - 0.72 9.1 6.7 0.86 8.9 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein SRR1 PF07985.12 ORX98484.1 - 7e-14 51.6 0.1 1.2e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 SRR1 HVSL PF09749.9 ORX98485.1 - 4e-58 196.7 0.0 5.3e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein LrgB PF04172.16 ORX98486.1 - 4e-16 59.2 1.1 4.7e-16 59.0 1.1 1.0 1 0 0 1 1 1 1 LrgB-like family Pro_isomerase PF00160.21 ORX98487.1 - 2.3e-45 154.7 0.0 2.7e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 ORX98489.1 - 1.8e-12 47.9 0.2 2.2e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX98489.1 - 4.4e-07 30.1 0.0 1.3e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX98490.1 - 7.8e-13 49.0 0.5 3.7e-10 40.4 0.3 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX98490.1 - 3.8e-08 33.5 0.3 4.6e-06 26.7 0.0 2.9 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain VHL PF01847.16 ORX98490.1 - 0.12 12.3 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 VHL beta domain SSI PF00720.17 ORX98491.1 - 3.8e-22 78.0 0.0 4.6e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Subtilisin inhibitor-like Myticin-prepro PF10690.9 ORX98498.1 - 0.029 14.6 0.3 0.044 14.0 0.3 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel SLM4 PF16818.5 ORX98503.1 - 0.045 13.7 0.7 0.073 13.0 0.7 1.4 1 0 0 1 1 1 0 Protein SLM4 MF_alpha_N PF05436.11 ORX98503.1 - 0.089 12.7 0.2 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus DUF4805 PF16063.5 ORX98505.1 - 0.014 14.7 1.3 0.018 14.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Lig_chan PF00060.26 ORX98506.1 - 0.06 13.2 0.0 0.076 12.9 0.0 1.3 1 1 0 1 1 1 0 Ligand-gated ion channel DLL_N PF12413.8 ORX98509.1 - 0.16 13.3 0.3 0.16 13.3 0.3 3.1 4 1 0 4 4 4 0 Homeobox protein distal-less-like N terminal Pkinase PF00069.25 ORX98513.1 - 5.5e-52 176.7 0.0 6.7e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98513.1 - 2.8e-37 128.4 0.0 4.9e-37 127.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX98513.1 - 1.7e-07 30.8 0.1 2.4e-06 27.1 0.2 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 ORX98513.1 - 0.01 15.8 0.1 0.11 12.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3155 PF11352.8 ORX98513.1 - 0.021 15.2 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) Haspin_kinase PF12330.8 ORX98513.1 - 0.076 11.9 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 ORX98514.1 - 2.3e-58 197.7 0.0 2.7e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98514.1 - 6.7e-37 127.2 0.0 7.4e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX98514.1 - 9.5e-09 35.0 0.1 1.6e-08 34.2 0.2 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORX98514.1 - 0.00012 21.0 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX98514.1 - 0.011 15.7 0.1 0.044 13.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family AbiEi_3_N PF17194.4 ORX98515.1 - 0.019 15.0 0.4 0.036 14.1 0.4 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain DUF4597 PF15366.6 ORX98516.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Pkinase PF00069.25 ORX98517.1 - 5.8e-06 25.9 0.0 8.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SBP_bac_8 PF13416.6 ORX98517.1 - 0.00011 22.2 4.6 0.00015 21.7 4.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Pkinase_Tyr PF07714.17 ORX98517.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 ORX98559.1 - 5.3e-53 180.2 49.1 5.3e-53 180.2 49.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX98559.1 - 4.8e-16 58.3 28.6 6.1e-16 58.0 28.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX98559.1 - 7.2e-15 54.8 13.9 7.2e-15 54.8 13.9 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter HMG_box PF00505.19 ORX98560.1 - 3.8e-43 145.7 1.9 1.4e-22 79.9 0.4 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX98560.1 - 2.4e-30 104.9 1.1 2.3e-15 56.9 0.3 2.3 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 ORX98560.1 - 1.3e-06 28.3 0.1 0.065 13.2 0.0 2.6 2 1 0 2 2 2 2 CHDNT (NUC034) domain HMG_box_5 PF14887.6 ORX98560.1 - 0.002 18.1 0.8 0.0063 16.5 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box 5 Ribosomal_L22 PF00237.19 ORX98561.1 - 4.8e-43 145.6 0.1 6.3e-43 145.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ABC2_membrane PF01061.24 ORX98562.1 - 3.3e-49 167.2 23.9 3.3e-49 167.2 23.9 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORX98562.1 - 3.3e-25 89.2 0.2 2.4e-24 86.4 0.2 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORX98562.1 - 9.4e-07 28.9 1.4 0.046 13.5 1.9 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX98562.1 - 5e-05 22.8 0.4 0.00029 20.3 0.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX98562.1 - 0.00052 19.9 0.2 0.001 19.0 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_35 PF14516.6 ORX98562.1 - 0.0019 17.1 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.6 ORX98562.1 - 0.0061 17.1 0.4 0.012 16.2 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORX98562.1 - 0.014 15.1 0.2 0.039 13.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX98562.1 - 0.031 14.7 0.1 0.052 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 ORX98562.1 - 0.059 12.5 31.7 0.061 12.4 30.2 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_5 PF07728.14 ORX98562.1 - 0.063 13.3 0.3 1.5 8.9 0.1 2.6 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORX98562.1 - 0.087 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORX98562.1 - 0.14 12.6 0.4 0.9 10.0 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORX98562.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORX98562.1 - 0.2 11.2 0.3 0.33 10.5 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORX98562.1 - 0.2 11.7 0.4 0.42 10.7 0.4 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane PF01061.24 ORX98563.1 - 2e-48 164.6 24.1 2e-48 164.6 24.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORX98563.1 - 3.6e-26 92.3 0.2 2.2e-24 86.5 0.2 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORX98563.1 - 8.8e-07 29.0 1.5 0.044 13.6 1.9 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX98563.1 - 5e-05 22.8 0.5 0.0003 20.3 0.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX98563.1 - 0.0007 19.5 0.3 0.0013 18.7 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ORX98563.1 - 0.0061 17.1 0.5 0.012 16.2 0.5 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 ORX98563.1 - 0.013 14.6 30.8 0.012 14.7 29.4 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_29 PF13555.6 ORX98563.1 - 0.014 15.1 0.3 0.04 13.6 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORX98563.1 - 0.03 14.7 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF1672 PF07901.11 ORX98563.1 - 0.036 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) AAA_5 PF07728.14 ORX98563.1 - 0.068 13.2 0.3 1.4 8.9 0.1 2.6 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORX98563.1 - 0.085 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORX98563.1 - 0.12 12.8 0.9 0.8 10.1 0.4 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 ORX98563.1 - 0.18 11.4 0.3 0.31 10.6 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORX98563.1 - 0.19 11.8 0.4 0.4 10.8 0.4 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase CTP_synth_N PF06418.14 ORX98564.1 - 1.2e-125 418.1 0.0 1.6e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ORX98564.1 - 1.3e-54 184.8 0.0 2.3e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORX98564.1 - 0.0011 18.8 0.0 0.0044 16.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Ribosomal_S21 PF01165.20 ORX98565.1 - 1.1e-14 53.9 4.7 1.7e-14 53.2 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DNA_methylase PF00145.17 ORX98566.1 - 1.5e-38 133.0 0.0 2.6e-38 132.2 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 ORX98566.1 - 0.0086 15.7 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase BTB_2 PF02214.22 ORX98567.1 - 0.0056 17.0 0.1 0.022 15.1 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain DUF4914 PF16260.5 ORX98567.1 - 0.018 13.2 0.0 0.023 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) ECH_1 PF00378.20 ORX98568.1 - 3.8e-89 298.3 0.3 4.8e-89 298.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORX98568.1 - 4.2e-33 115.2 0.2 5e-31 108.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORX98568.1 - 0.0011 19.0 0.4 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 DUF3813 PF12758.7 ORX98568.1 - 0.072 13.4 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) GYF PF02213.16 ORX98569.1 - 3.7e-19 68.1 0.9 1.1e-18 66.5 0.6 2.1 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 ORX98569.1 - 4.1e-07 29.7 0.0 2.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 GYF domain 2 Lant_dehydr_C PF14028.6 ORX98570.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Lant_dehydr_C PF14028.6 ORX98571.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term SAICAR_synt PF01259.18 ORX98572.1 - 1.1e-99 333.2 0.0 1.3e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase CBS PF00571.28 ORX98573.1 - 4.1e-31 107.2 6.7 1.4e-08 35.0 0.1 4.3 4 0 0 4 4 4 4 CBS domain AbiEi_4 PF13338.6 ORX98573.1 - 0.0046 17.1 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin ALG11_N PF15924.5 ORX98574.1 - 4e-91 304.7 0.4 8.8e-91 303.6 0.4 1.6 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 ORX98574.1 - 5.6e-28 97.6 0.0 8.9e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORX98574.1 - 5.3e-13 49.6 0.0 9.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORX98574.1 - 0.00051 20.4 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RINT1_TIP1 PF04437.13 ORX98575.1 - 8.6e-126 420.7 1.0 8.6e-126 420.7 1.0 1.7 2 1 0 2 2 2 1 RINT-1 / TIP-1 family DUF507 PF04368.13 ORX98575.1 - 0.099 12.6 5.0 0.086 12.8 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF507) SspB PF04386.13 ORX98575.1 - 0.12 12.3 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 Stringent starvation protein B Glutaredoxin2_C PF04399.13 ORX98575.1 - 0.25 11.2 2.2 0.96 9.3 0.7 2.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain APG6_N PF17675.1 ORX98575.1 - 0.31 11.6 8.7 0.95 10.0 8.7 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region COMPASS-Shg1 PF05205.12 ORX98575.1 - 3.8 8.3 7.0 24 5.7 0.0 4.1 3 1 1 4 4 4 0 COMPASS (Complex proteins associated with Set1p) component shg1 Carbpep_Y_N PF05388.11 ORX98575.1 - 8.6 6.9 7.4 12 6.4 1.5 3.5 1 1 1 3 3 3 0 Carboxypeptidase Y pro-peptide Trypan_PARP PF05887.11 ORX98576.1 - 0.023 14.7 3.4 0.27 11.2 0.9 2.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 ORX98577.1 - 5e-68 229.3 0.0 5.9e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98577.1 - 7.8e-35 120.4 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX98577.1 - 0.012 14.6 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORX98577.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Carn_acyltransf PF00755.20 ORX98578.1 - 6.2e-201 669.0 0.0 7e-201 668.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AA_permease PF00324.21 ORX98579.1 - 1.5e-133 445.9 44.8 1.7e-133 445.8 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX98579.1 - 2.3e-40 138.7 51.7 4.8e-40 137.7 51.3 1.6 1 1 0 1 1 1 1 Amino acid permease DDE_Tnp_1_assoc PF13808.6 ORX98579.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-associated AA_permease PF00324.21 ORX98580.1 - 6.3e-135 450.5 40.5 7.4e-135 450.2 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX98580.1 - 5.8e-43 147.3 41.7 8.1e-43 146.8 41.3 1.4 1 1 1 2 2 2 2 Amino acid permease TAF1_subA PF14929.6 ORX98581.1 - 2e-15 57.1 0.4 2.9e-15 56.6 0.4 1.2 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_2 PF07719.17 ORX98581.1 - 7.9e-07 28.7 0.1 0.067 13.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORX98581.1 - 1.3e-06 28.7 0.0 0.00075 20.1 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORX98581.1 - 9.5e-05 22.0 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 ORX98581.1 - 0.00098 19.6 0.0 0.0034 17.9 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98581.1 - 0.0032 17.6 0.2 12 6.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 ORX98581.1 - 0.024 15.3 0.0 0.055 14.2 0.0 1.6 1 0 0 1 1 1 0 Sel1 repeat ANAPC3 PF12895.7 ORX98581.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ORX98581.1 - 0.044 13.6 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CP12 PF02672.15 ORX98581.1 - 0.046 14.5 0.2 0.23 12.2 0.2 2.1 1 1 0 1 1 1 0 CP12 domain HrpB1_HrpK PF09613.10 ORX98581.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) E1-E2_ATPase PF00122.20 ORX98582.1 - 1.9e-48 164.4 0.5 1.9e-48 164.4 0.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX98582.1 - 2e-25 89.5 10.8 2.7e-19 69.6 1.0 3.3 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX98582.1 - 7.5e-21 74.0 0.0 1.8e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX98582.1 - 4.1e-17 63.2 0.1 1.2e-14 55.2 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX98582.1 - 2.3e-14 52.8 0.0 4.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX98582.1 - 6.8e-05 22.7 0.7 0.021 14.6 0.4 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase COX7a PF02238.15 ORX98583.1 - 1.9e-18 66.6 0.1 2.1e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII GPCR_chapero_1 PF11904.8 ORX98584.1 - 1.7e-08 34.2 0.0 5.5e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 ORX98584.1 - 0.00037 21.0 0.0 0.0012 19.3 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORX98584.1 - 0.00083 19.6 0.0 0.19 12.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORX98584.1 - 0.003 18.1 0.1 0.022 15.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORX98584.1 - 0.025 15.0 0.1 0.22 12.0 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 ORX98584.1 - 0.13 12.6 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF726 PF05277.12 ORX98585.1 - 2e-103 346.0 0.3 2.8e-103 345.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Myco_arth_vir_N PF09610.10 ORX98585.1 - 6.9 6.8 5.7 0.94 9.6 0.2 2.5 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Thioredoxin PF00085.20 ORX98586.1 - 7.8e-24 83.6 0.1 9.2e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ORX98586.1 - 6e-08 32.7 0.0 6.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ORX98586.1 - 1.1e-06 28.9 0.1 1.7e-05 25.1 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ORX98586.1 - 2.7e-05 24.0 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORX98586.1 - 6.5e-05 22.4 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 ORX98586.1 - 0.00024 21.0 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 ORX98586.1 - 0.00038 20.2 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 ORX98586.1 - 0.00045 20.3 0.0 0.00092 19.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORX98586.1 - 0.0016 18.9 0.2 0.11 13.0 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 ORX98586.1 - 0.016 15.0 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF953 PF06110.11 ORX98586.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AAA PF00004.29 ORX98587.1 - 1.3e-31 109.8 0.1 2.1e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORX98587.1 - 1.7e-07 31.6 0.2 1.6e-06 28.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORX98587.1 - 8.5e-07 29.5 0.0 2.4e-06 28.0 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 ORX98587.1 - 5.3e-06 27.0 0.3 1.8e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX98587.1 - 3e-05 24.2 0.1 0.00013 22.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORX98587.1 - 6.8e-05 22.5 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORX98587.1 - 8.3e-05 22.6 0.0 0.00023 21.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 ORX98587.1 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 ORX98587.1 - 0.00039 20.4 0.5 0.018 14.9 0.5 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORX98587.1 - 0.00044 20.0 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 ORX98587.1 - 0.00048 20.1 0.1 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 ORX98587.1 - 0.00049 19.9 0.1 0.00094 19.0 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 ORX98587.1 - 0.00057 20.2 0.0 0.0021 18.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 ORX98587.1 - 0.00059 19.7 0.1 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 ORX98587.1 - 0.00086 19.7 0.0 0.0023 18.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 ORX98587.1 - 0.0014 18.4 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 ORX98587.1 - 0.002 17.4 0.1 0.013 14.7 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 ORX98587.1 - 0.0023 18.3 0.1 0.013 15.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ORX98587.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 ORX98587.1 - 0.0028 17.5 0.1 0.0085 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORX98587.1 - 0.0056 16.7 0.1 0.014 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 ORX98587.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 ORX98587.1 - 0.0071 16.3 0.1 0.024 14.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 ORX98587.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORX98587.1 - 0.014 14.8 0.2 0.99 8.7 0.0 2.4 1 1 0 2 2 2 0 KaiC TIP49 PF06068.13 ORX98587.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain PhoH PF02562.16 ORX98587.1 - 0.019 14.4 0.0 0.27 10.7 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 ORX98587.1 - 0.02 15.4 0.0 0.044 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 ORX98587.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 ORX98587.1 - 0.031 14.6 0.2 0.28 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORX98587.1 - 0.032 14.0 0.1 0.092 12.5 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 ORX98587.1 - 0.058 12.6 0.3 1.2 8.3 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.21 ORX98587.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 ORX98587.1 - 0.07 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 ORX98587.1 - 0.081 12.8 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.18 ORX98587.1 - 0.09 12.1 0.1 4 6.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_3 PF07726.11 ORX98587.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elong_Iki1 PF10483.9 ORX98588.1 - 5.6e-35 121.3 0.2 8.1e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 PRKCSH PF07915.13 ORX98589.1 - 4e-13 50.2 2.5 4e-13 50.2 2.5 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 ORX98589.1 - 0.00027 20.7 0.9 0.0011 18.7 0.9 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein MoaE PF02391.17 ORX98590.1 - 3.2e-40 136.9 0.0 3.7e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 MoaE protein TRAP_alpha PF03896.16 ORX98591.1 - 1.1e-21 77.4 0.1 1.2e-21 77.2 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ycf70 PF17382.2 ORX98591.1 - 0.085 13.3 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized Ycf70-like TPX2 PF06886.11 ORX98592.1 - 7e-06 26.2 3.5 7e-06 26.2 3.5 3.9 4 0 0 4 4 4 2 Targeting protein for Xklp2 (TPX2) DUF3474 PF11960.8 ORX98592.1 - 0.19 11.9 1.9 0.56 10.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Utp14 PF04615.13 ORX98593.1 - 3e-207 690.7 73.0 3e-207 690.7 73.0 2.1 1 1 1 2 2 2 1 Utp14 protein SLAC1 PF03595.17 ORX98594.1 - 1.7e-67 228.0 40.7 1.9e-67 227.9 40.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 ORX98595.1 - 8.1e-41 140.3 19.7 9.1e-41 140.2 19.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 ORX98596.1 - 5.2e-33 114.7 20.3 5.9e-33 114.5 20.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 ORX98597.1 - 5.2e-33 114.7 20.3 5.9e-33 114.5 20.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 ORX98598.1 - 5.2e-33 114.7 20.3 5.9e-33 114.5 20.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ABC_tran PF00005.27 ORX98599.1 - 1.3e-49 168.2 0.0 9.7e-28 97.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORX98599.1 - 3.5e-45 154.8 54.6 4e-26 92.3 20.7 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ORX98599.1 - 6.7e-12 45.3 0.9 8.8e-05 22.0 0.1 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORX98599.1 - 0.00016 21.8 0.8 0.42 10.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX98599.1 - 0.00071 19.3 0.2 0.79 9.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORX98599.1 - 0.0017 18.3 0.1 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 ORX98599.1 - 0.0019 18.3 0.6 0.52 10.4 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 ORX98599.1 - 0.0034 17.8 0.2 0.85 10.0 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 ORX98599.1 - 0.042 13.9 3.7 0.34 10.9 0.1 2.9 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.6 ORX98599.1 - 0.066 13.5 1.3 4.9 7.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 ORX98599.1 - 0.76 8.8 34.3 0.36 9.9 3.4 3.6 3 0 0 3 3 3 0 ABC-2 family transporter protein Oxidored_q4 PF00507.19 ORX98621.1 - 2.1e-26 92.0 3.1 3.3e-26 91.3 3.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 TMEM100 PF16311.5 ORX98621.1 - 0.11 12.1 1.4 0.17 11.5 1.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF3043 PF11241.8 ORX98621.1 - 2.4 8.2 4.6 0.95 9.5 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Tmemb_55A PF09788.9 ORX98621.1 - 2.7 7.0 4.3 4 6.5 4.1 1.4 1 1 0 1 1 1 0 Transmembrane protein 55A Pkinase PF00069.25 ORX98622.1 - 1.6e-43 149.0 0.0 2e-25 89.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98622.1 - 3.1e-25 89.0 0.0 8.4e-14 51.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase DivIC PF04977.15 ORX98622.1 - 0.017 14.8 0.7 0.054 13.3 0.1 2.2 3 0 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 ORX98622.1 - 0.036 14.1 1.0 0.12 12.5 1.0 1.8 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 ORX98622.1 - 0.14 12.4 1.7 0.32 11.3 1.7 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper TM231 PF10149.9 ORX98622.1 - 0.15 11.4 0.1 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 231 HisKA_3 PF07730.13 ORX98622.1 - 0.17 12.4 2.2 0.55 10.8 0.1 2.4 2 0 0 2 2 2 0 Histidine kinase DASH_Hsk3 PF08227.11 ORX98622.1 - 0.33 11.3 4.5 0.81 10.1 4.5 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like SIKE PF05769.11 ORX98622.1 - 0.41 10.5 4.9 0.82 9.6 1.6 2.2 2 0 0 2 2 2 0 SIKE family NYD-SP28_assoc PF14775.6 ORX98622.1 - 0.82 9.8 6.3 0.44 10.7 3.0 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain NAD_binding_10 PF13460.6 ORX98623.1 - 2.1e-43 148.3 0.0 2.4e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX98623.1 - 8.4e-11 41.9 0.2 1.7e-10 40.8 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 ORX98623.1 - 4e-06 26.5 0.2 7.9e-06 25.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORX98623.1 - 0.00027 20.1 0.4 0.00039 19.5 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORX98623.1 - 0.0021 17.2 0.1 0.0076 15.4 0.1 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ORX98623.1 - 0.0053 16.2 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 ORX98623.1 - 0.021 15.4 0.4 0.041 14.5 0.1 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ORX98623.1 - 0.039 14.4 0.1 0.058 13.8 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORX98623.1 - 0.046 14.0 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 ORX98623.1 - 0.049 13.8 0.2 0.078 13.1 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 ORX98623.1 - 0.08 13.2 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lipase_3 PF01764.25 ORX98625.1 - 8.7e-27 93.7 0.0 9.5e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORX98625.1 - 1.1e-06 28.4 0.1 1.6e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORX98625.1 - 0.0014 19.2 0.0 0.0015 19.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORX98625.1 - 0.0042 16.8 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 ORX98625.1 - 0.0047 16.5 0.0 0.0056 16.2 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ORX98625.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORX98625.1 - 0.031 14.1 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ORX98625.1 - 0.033 13.9 0.3 0.056 13.1 0.2 1.4 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 ORX98625.1 - 0.083 12.3 0.2 0.12 11.8 0.2 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Tachylectin PF14517.6 ORX98626.1 - 5.1e-05 22.9 10.1 0.023 14.3 5.7 3.5 1 1 1 2 2 2 2 Tachylectin Hyd_WA PF06462.12 ORX98626.1 - 0.00034 20.6 13.5 0.56 10.3 0.0 5.3 5 0 0 5 5 5 3 Propeller Fim-adh_lectin PF09222.10 ORX98626.1 - 0.047 13.2 1.7 0.072 12.6 1.5 1.4 1 1 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain DUF3756 PF12581.8 ORX98626.1 - 4.8 7.2 13.7 18 5.4 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3756) PH PF00169.29 ORX98627.1 - 0.00031 21.2 0.1 0.00081 19.9 0.1 1.8 1 1 0 1 1 1 1 PH domain DUF5089 PF17002.5 ORX98627.1 - 0.024 14.5 0.2 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) GST_C_3 PF14497.6 ORX98629.1 - 2.2e-24 85.5 0.4 4.4e-24 84.6 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98629.1 - 1.2e-10 41.5 0.1 2.1e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX98629.1 - 1.7e-07 31.5 0.0 5.8e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORX98629.1 - 0.01 16.3 0.0 0.078 13.4 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX98629.1 - 0.048 13.7 0.1 0.2 11.7 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sep15_SelM PF08806.11 ORX98629.1 - 0.15 12.3 0.1 2.8 8.2 0.0 2.5 2 1 0 2 2 2 0 Sep15/SelM redox domain GST_C_3 PF14497.6 ORX98630.1 - 3.4e-24 84.9 0.5 6e-24 84.1 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98630.1 - 5.4e-09 36.2 0.2 1.1e-08 35.2 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX98630.1 - 6e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX98630.1 - 0.0026 17.8 0.0 0.0082 16.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX98630.1 - 0.052 14.0 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORX98631.1 - 1.1e-22 80.1 0.1 1.8e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX98631.1 - 9.2e-14 51.5 0.0 2.2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORX98631.1 - 5.8e-10 39.3 0.1 9.5e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX98631.1 - 8.1e-08 32.6 0.0 3.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX98631.1 - 9.8e-06 25.8 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX98631.1 - 0.048 13.7 0.1 0.27 11.3 0.1 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PAS_3 PF08447.12 ORX98632.1 - 5.8e-06 26.5 0.0 0.021 15.1 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 ORX98632.1 - 0.00023 21.4 0.0 0.0022 18.2 0.0 2.3 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 ORX98632.1 - 0.0093 16.0 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ORX98632.1 - 0.055 13.7 0.0 4.9 7.5 0.0 2.5 2 1 0 2 2 2 0 PAS fold Gti1_Pac2 PF09729.9 ORX98633.1 - 8e-42 143.4 3.9 1.7e-37 129.3 0.7 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family COX6B PF02297.17 ORX98634.1 - 1.6e-19 69.9 5.6 2e-19 69.6 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 ORX98634.1 - 0.027 14.5 1.5 0.044 13.8 1.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 ORX98634.1 - 0.038 13.9 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 ORX98634.1 - 0.067 12.8 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain YozE_SAM_like PF06855.12 ORX98634.1 - 0.084 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 YozE SAM-like fold Sec1 PF00995.23 ORX98635.1 - 2.3e-130 436.6 6.3 2.7e-130 436.3 6.3 1.1 1 0 0 1 1 1 1 Sec1 family Peptidase_M41 PF01434.18 ORX98636.1 - 4.7e-66 222.3 0.0 8e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORX98636.1 - 3.3e-43 147.3 0.0 6.2e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX98636.1 - 4.7e-15 55.1 0.7 1.1e-14 53.9 0.3 1.8 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 ORX98636.1 - 4.7e-11 43.0 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 ORX98636.1 - 0.0023 18.4 0.1 0.036 14.5 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 ORX98636.1 - 0.0038 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 ORX98636.1 - 0.0072 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORX98636.1 - 0.0083 16.4 0.0 0.67 10.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORX98636.1 - 0.019 15.0 0.0 0.082 12.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ORX98636.1 - 0.036 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain SPATIAL PF15256.6 ORX98636.1 - 0.082 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 SPATIAL IstB_IS21 PF01695.17 ORX98636.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 ORX98636.1 - 0.11 12.6 0.0 0.4 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORX98636.1 - 0.17 12.1 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 ORX98636.1 - 0.18 11.1 0.3 0.51 9.7 0.3 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-H2C2_2 PF13465.6 ORX98637.1 - 2.7e-05 24.4 1.8 2.7e-05 24.4 1.8 3.0 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORX98637.1 - 5.7e-05 23.4 19.6 0.00015 22.0 2.4 3.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORX98637.1 - 0.0054 16.7 0.7 0.0054 16.7 0.7 2.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORX98637.1 - 0.0055 17.4 1.5 0.0055 17.4 1.5 3.0 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX98637.1 - 0.017 15.4 0.9 0.017 15.4 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 ORX98637.1 - 0.021 14.4 0.2 0.056 13.1 0.2 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 ORX98637.1 - 0.1 12.9 5.6 0.063 13.6 3.7 1.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon Cytochrom_c3_2 PF14537.6 ORX98637.1 - 3 8.4 9.5 19 5.8 9.5 2.0 1 1 0 1 1 1 0 Cytochrome c3 Acetyltransf_3 PF13302.7 ORX98639.1 - 1.6e-16 61.2 0.0 2.5e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX98639.1 - 2.2e-06 27.9 0.0 3.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family KH_1 PF00013.29 ORX98640.1 - 1.5e-41 140.0 12.0 6.6e-17 61.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORX98640.1 - 8.2e-10 38.4 10.3 0.014 15.2 1.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORX98640.1 - 2.5e-08 33.7 5.6 0.025 14.4 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORX98640.1 - 1.7e-05 24.8 3.9 0.067 13.3 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain SPO22 PF08631.10 ORX98641.1 - 8.5e-05 22.2 25.2 0.0001 21.9 4.4 5.6 1 1 2 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 ORX98641.1 - 0.06 14.0 0.1 0.39 11.4 0.1 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5576 PF17739.1 ORX98641.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5576) ANAPC3 PF12895.7 ORX98641.1 - 0.12 12.6 2.1 0.32 11.2 0.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Retrotrans_gag PF03732.17 ORX98641.1 - 0.26 11.6 1.9 0.85 9.9 0.6 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein TPR_8 PF13181.6 ORX98641.1 - 0.7 10.3 3.0 3.7 8.0 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2203 PF09969.9 ORX98641.1 - 2.5 8.8 5.3 6.2 7.6 0.4 3.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) bZIP_2 PF07716.15 ORX98642.1 - 9.8e-08 32.0 16.4 1.4e-07 31.4 6.7 2.2 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORX98642.1 - 5.3e-07 29.6 11.8 5.3e-07 29.6 11.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor DUF3450 PF11932.8 ORX98642.1 - 0.015 14.6 10.8 0.019 14.3 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 ORX98642.1 - 0.032 14.7 10.9 0.064 13.8 10.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor FAM76 PF16046.5 ORX98642.1 - 0.099 12.0 4.6 0.13 11.6 4.6 1.1 1 0 0 1 1 1 0 FAM76 protein Wza_C PF18412.1 ORX98642.1 - 0.13 12.0 0.3 0.33 10.7 0.3 1.7 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain Shugoshin_N PF07558.11 ORX98642.1 - 0.26 11.2 6.0 0.27 11.1 1.6 2.6 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF1465 PF07323.12 ORX98642.1 - 0.44 10.4 8.3 0.74 9.6 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Hira PF07569.11 ORX98642.1 - 0.74 9.5 4.7 1.2 8.8 4.7 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split Nup54 PF13874.6 ORX98642.1 - 0.78 9.9 10.0 1.2 9.3 10.0 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-C2H2 PF00096.26 ORX98643.1 - 6.6e-15 54.6 20.7 6.1e-06 26.4 6.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX98643.1 - 4.9e-14 52.0 23.2 7.7e-07 29.3 1.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX98643.1 - 2e-09 37.5 18.7 0.0028 18.4 4.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORX98643.1 - 8.8e-05 22.7 7.3 0.22 11.8 1.5 2.9 1 1 0 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORX98643.1 - 0.026 15.1 3.2 16 6.2 0.1 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORX98643.1 - 0.46 10.6 7.3 5.9 7.0 4.3 2.5 1 1 1 2 2 2 0 Aberrant zinc-finger Cg6151-P PF10233.9 ORX98644.1 - 5.9e-09 36.2 10.5 7.6e-09 35.9 10.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P HCV_NS2 PF01538.18 ORX98644.1 - 0.075 12.7 0.1 0.076 12.7 0.1 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 7tm_6 PF02949.20 ORX98644.1 - 1.3 8.0 7.2 1.5 7.8 7.2 1.1 1 0 0 1 1 1 0 7tm Odorant receptor Ribosomal_L34e PF01199.18 ORX98645.1 - 1.6e-46 156.5 4.1 2.1e-46 156.1 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e MgsA_C PF12002.8 ORX98646.1 - 1.6e-57 194.1 0.1 4.2e-57 192.7 0.0 1.6 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 ORX98646.1 - 7.4e-25 87.1 0.1 1.3e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 ORX98646.1 - 1.7e-17 64.0 0.0 3.1e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORX98646.1 - 9e-13 48.3 0.0 1.9e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORX98646.1 - 4.3e-06 26.8 0.1 0.00021 21.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ORX98646.1 - 5.8e-06 26.1 0.0 0.0075 16.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 ORX98646.1 - 3.7e-05 24.2 0.4 0.03 14.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 ORX98646.1 - 0.00031 21.3 0.0 0.0011 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 ORX98646.1 - 0.0005 20.2 0.0 0.00083 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 ORX98646.1 - 0.00089 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX98646.1 - 0.002 18.4 0.3 0.3 11.4 0.0 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORX98646.1 - 0.0041 16.5 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 ORX98646.1 - 0.005 17.0 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.15 ORX98646.1 - 0.024 14.6 0.1 3.5 7.6 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORX98646.1 - 0.047 14.0 0.3 8.4 6.7 0.1 2.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 ORX98646.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORX98646.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 ORX98646.1 - 0.082 12.1 0.0 0.49 9.5 0.0 1.9 1 1 1 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 ORX98646.1 - 0.097 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 ORX98646.1 - 0.1 12.9 0.0 0.24 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 ORX98646.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORX98646.1 - 0.12 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORX98646.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 ORX98646.1 - 0.16 11.8 0.0 0.59 10.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 ORX98646.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Parvo_NS1 PF01057.17 ORX98646.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GST_C_3 PF14497.6 ORX98647.1 - 2.2e-25 88.7 0.5 4e-25 87.9 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98647.1 - 2.7e-10 40.3 0.1 5.6e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX98647.1 - 4.7e-07 30.1 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX98647.1 - 0.00019 21.4 0.1 0.0005 20.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX98647.1 - 0.0046 17.3 0.0 0.024 15.1 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX98647.1 - 0.0064 16.8 0.0 0.025 14.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORX98648.1 - 2.6e-24 85.3 0.5 4.6e-24 84.5 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98648.1 - 2.9e-08 33.8 0.1 6.4e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX98648.1 - 6.3e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORX98648.1 - 0.0014 18.6 0.0 0.0047 16.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORX98648.1 - 0.052 14.0 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GCV_T PF01571.21 ORX98649.1 - 1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Sod_Fe_C PF02777.18 ORX98650.1 - 1.9e-39 133.9 0.5 3.6e-39 133.0 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORX98650.1 - 2.9e-33 114.2 2.1 8e-33 112.8 2.1 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PDH PF02153.17 ORX98652.1 - 1.3e-18 67.0 0.0 1.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 ORX98652.1 - 2.9e-05 24.6 0.0 6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORX98652.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ORX98652.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ORX98652.1 - 0.0076 15.9 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ORX98652.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 ORX98653.1 - 3.9e-40 135.1 32.7 8.1e-07 29.7 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 ORX98653.1 - 8.5e-12 44.5 4.3 0.25 10.0 0.0 5.4 3 2 1 5 5 5 5 Nucleoporin Nup120/160 F-box-like PF12937.7 ORX98653.1 - 2.4e-11 43.3 1.4 2.4e-11 43.3 1.4 2.0 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 ORX98653.1 - 6e-11 42.5 3.2 0.62 10.4 0.0 5.7 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORX98653.1 - 3.5e-06 26.7 0.5 9.9e-06 25.3 0.5 1.8 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 ORX98653.1 - 3.8e-06 26.4 1.5 5.6e-05 22.6 0.3 2.2 1 1 1 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 ORX98653.1 - 8e-06 25.9 0.0 0.32 11.0 0.0 4.0 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 ORX98653.1 - 0.00015 21.4 0.1 0.14 11.7 0.2 2.6 1 1 1 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 ORX98653.1 - 0.002 18.0 0.1 0.0087 15.9 0.1 2.2 1 0 0 1 1 1 1 F-box DUF5046 PF16465.5 ORX98653.1 - 0.018 14.5 0.1 3.9 6.8 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) FlaG PF03646.15 ORX98653.1 - 0.04 14.1 0.0 7 6.9 0.0 3.2 3 0 0 3 3 3 0 FlaG protein Urease_beta PF00699.20 ORX98653.1 - 0.1 12.6 0.0 3.2 7.8 0.0 2.8 2 1 1 3 3 3 0 Urease beta subunit Hira PF07569.11 ORX98653.1 - 0.48 10.1 6.3 15 5.2 0.0 4.8 4 2 3 7 7 7 0 TUP1-like enhancer of split Peptidase_S8 PF00082.22 ORX98654.1 - 8.4e-35 120.5 6.8 1.8e-34 119.3 6.8 1.4 1 1 0 1 1 1 1 Subtilase family Myb_DNA-bind_7 PF15963.5 ORX98655.1 - 1.6e-05 24.7 0.1 1.6e-05 24.7 0.1 3.0 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORX98655.1 - 2.5e-05 24.4 0.0 8.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX98655.1 - 0.00065 19.9 0.5 0.005 17.1 0.2 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain APG5 PF04106.12 ORX98655.1 - 0.072 12.7 1.8 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg5 NusB PF01029.18 ORX98655.1 - 0.16 12.2 1.9 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 NusB family Maf PF02545.14 ORX98656.1 - 1.2e-55 187.9 0.0 1.4e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein CorA PF01544.18 ORX98657.1 - 3.9e-49 167.5 0.5 4.8e-49 167.3 0.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2605 PF10792.9 ORX98657.1 - 0.15 12.0 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) DUF3626 PF12294.8 ORX98658.1 - 5.6e-59 199.6 1.7 2.9e-37 128.3 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3626) AhpC-TSA PF00578.21 ORX98659.1 - 4.5e-27 94.4 0.0 6e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 ORX98659.1 - 3.3e-11 42.8 0.0 5.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 ORX98659.1 - 8.5e-10 38.5 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin Sugar_tr PF00083.24 ORX98690.1 - 9.2e-103 344.5 28.5 1.1e-102 344.2 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX98690.1 - 2.3e-21 76.2 51.4 8.2e-19 67.7 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 ORX98692.1 - 9.8e-28 97.3 0.0 1.6e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX98692.1 - 7.8e-20 71.5 0.0 1.3e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORX98692.1 - 1.2e-08 34.7 0.5 1.7e-05 24.4 0.3 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORX98692.1 - 4.7e-05 23.6 0.9 8.8e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ORX98692.1 - 0.0018 17.7 0.2 0.0041 16.6 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ORX98692.1 - 0.0061 16.0 0.3 0.59 9.5 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 ORX98692.1 - 0.067 13.1 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 KR domain Arrestin_N PF00339.29 ORX98694.1 - 4.2e-10 39.9 0.0 1.5e-07 31.6 0.0 2.4 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX98694.1 - 1.5e-09 38.4 0.1 2.5e-06 28.0 0.2 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORX98694.1 - 0.083 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Rgp1 Sugarporin_N PF11471.8 ORX98695.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension PRESAN PF09687.10 ORX98696.1 - 0.014 16.0 0.8 0.033 14.7 0.8 1.6 1 0 0 1 1 1 0 Plasmodium RESA N-terminal Mem_trans PF03547.18 ORX98697.1 - 1.2e-10 40.3 2.2 1.3e-10 40.3 2.2 1.2 1 0 0 1 1 1 1 Membrane transport protein Flp1_like PF16982.5 ORX98697.1 - 0.18 11.2 1.7 0.46 9.9 1.7 1.6 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Ribosomal_S9 PF00380.19 ORX98698.1 - 6e-34 117.2 0.2 6.8e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 ORX98699.1 - 4.8e-82 274.2 7.9 6.5e-82 273.7 7.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L32e PF01655.18 ORX98700.1 - 1e-53 180.3 2.7 1e-53 180.3 2.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L32 Ribosomal_S3_C PF00189.20 ORX98701.1 - 9.8e-24 83.7 1.1 3.8e-23 81.8 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORX98701.1 - 1.2e-12 47.5 0.1 2.1e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 ORX98701.1 - 0.043 14.3 0.0 0.081 13.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 ORX98701.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus Invasin_D3 PF09134.10 ORX98702.1 - 0.082 13.2 0.3 0.18 12.1 0.3 1.5 1 0 0 1 1 1 0 Invasin, domain 3 tRNA-synt_1 PF00133.22 ORX98703.1 - 3.9e-63 213.7 0.7 2.8e-19 68.8 0.8 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 ORX98703.1 - 5.5e-56 189.0 0.0 1.1e-55 188.1 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ORX98703.1 - 5.3e-27 94.6 1.4 2.6e-19 69.3 0.0 4.6 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORX98703.1 - 2.3e-14 53.6 0.0 4.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1664 PF07889.12 ORX98704.1 - 0.013 15.6 12.1 0.18 11.9 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 ORX98704.1 - 0.33 10.5 12.3 1.5 8.4 4.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) UPF0242 PF06785.11 ORX98704.1 - 0.62 10.1 33.3 0.43 10.7 4.5 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 ORX98704.1 - 1.2 7.6 7.1 2.3 6.6 7.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM76 PF16046.5 ORX98704.1 - 1.5 8.1 10.2 0.97 8.7 5.2 2.3 2 0 0 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 ORX98704.1 - 2.4 7.6 17.2 1.4 8.4 12.7 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 ORX98704.1 - 5.5 7.5 10.0 12 6.5 0.1 3.4 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Enolase_C PF00113.22 ORX98705.1 - 1.7e-155 516.6 0.1 2.9e-155 515.9 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORX98705.1 - 2.3e-58 196.0 0.3 3.7e-58 195.4 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORX98705.1 - 4.1e-10 39.6 0.0 5.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORX98705.1 - 0.00037 19.7 0.2 0.00086 18.5 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Gp_dh_C PF02800.20 ORX98706.1 - 2.5e-71 238.4 0.0 3.9e-71 237.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORX98706.1 - 1.8e-40 137.3 0.2 3.4e-40 136.4 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORX98706.1 - 0.0071 16.5 0.2 0.04 14.0 0.0 2.4 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.25 ORX98707.1 - 1.2e-61 208.4 0.0 1.6e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98707.1 - 2.9e-28 98.9 0.0 4.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORX98707.1 - 0.068 12.5 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like IP_trans PF02121.18 ORX98708.1 - 9.9e-109 362.6 0.2 1.2e-108 362.4 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein 5_nucleotid_C PF02872.18 ORX98709.1 - 1.6e-23 83.7 0.0 2.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORX98709.1 - 1.1e-12 48.9 0.3 2.2e-12 47.9 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosom_S12_S23 PF00164.25 ORX98710.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IATP PF04568.12 ORX98711.1 - 3.6e-14 53.0 1.5 4.1e-14 52.8 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FAP206 PF12018.8 ORX98711.1 - 0.0017 17.9 0.4 0.0017 17.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function Rx_N PF18052.1 ORX98711.1 - 0.038 14.3 0.9 0.047 14.0 0.9 1.2 1 0 0 1 1 1 0 Rx N-terminal domain DUF4140 PF13600.6 ORX98711.1 - 0.07 13.6 1.3 0.079 13.4 1.3 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ApoO PF09769.9 ORX98711.1 - 0.11 12.5 1.5 6.8 6.7 0.7 2.0 1 1 1 2 2 2 0 Apolipoprotein O YgaB PF14182.6 ORX98711.1 - 0.13 12.7 4.7 0.17 12.3 4.7 1.2 1 0 0 1 1 1 0 YgaB-like protein DUF1043 PF06295.12 ORX98711.1 - 0.33 11.0 7.9 0.24 11.4 6.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Pkinase PF00069.25 ORX98712.1 - 1.2e-55 188.8 0.0 1.5e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98712.1 - 3.4e-25 88.8 0.2 7.6e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORX98712.1 - 0.002 18.1 0.0 0.0064 16.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORX98712.1 - 0.0078 15.8 0.4 0.017 14.8 0.3 1.6 1 1 0 1 1 1 1 RIO1 family ABC1 PF03109.16 ORX98712.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 ORX98712.1 - 0.094 12.0 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Methyltransf_11 PF08241.12 ORX98715.1 - 3.1e-20 72.6 0.1 6.5e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX98715.1 - 6.5e-19 68.4 0.0 1.5e-17 64.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX98715.1 - 2.1e-17 63.3 0.0 2.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX98715.1 - 4.9e-17 62.5 0.0 9.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX98715.1 - 1.1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORX98715.1 - 4.4e-07 29.6 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ORX98715.1 - 2.4e-06 26.7 0.0 3.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.12 ORX98715.1 - 6.1e-06 25.5 0.0 1.6e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 DREV methyltransferase NodS PF05401.11 ORX98715.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 ORX98715.1 - 0.00015 20.9 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 ORX98715.1 - 0.00041 20.0 0.1 0.00075 19.1 0.0 1.4 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ORX98715.1 - 0.00079 18.8 0.0 0.0056 16.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 ORX98715.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 ORX98715.1 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORX98715.1 - 0.0052 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORX98715.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ORX98715.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 ORX98715.1 - 0.023 14.2 0.0 2.7 7.4 0.0 2.9 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.26 ORX98715.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PAC4 PF16093.5 ORX98716.1 - 1.6e-17 63.5 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 PAP2 PF01569.21 ORX98717.1 - 1.5e-29 102.5 1.2 1.5e-29 102.5 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORX98717.1 - 0.00027 20.7 5.0 0.0015 18.2 4.5 2.3 1 1 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 ORX98717.1 - 0.028 14.3 0.0 0.099 12.6 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Strabismus PF06638.11 ORX98717.1 - 0.28 9.8 0.0 0.6 8.7 0.0 1.5 2 0 0 2 2 2 0 Strabismus protein 6PF2K PF01591.18 ORX98718.1 - 8.7e-84 280.3 0.6 1.3e-83 279.7 0.6 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORX98718.1 - 2.8e-38 131.6 0.0 3.9e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORX98718.1 - 3.8e-05 23.9 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain His_Phos_2 PF00328.22 ORX98718.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) KTI12 PF08433.10 ORX98718.1 - 0.051 13.0 0.0 0.22 10.9 0.0 1.9 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Ank_2 PF12796.7 ORX98719.1 - 6.3e-07 29.9 0.1 0.00019 21.9 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORX98719.1 - 0.0014 18.9 0.0 1.1 9.6 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) HSP70 PF00012.20 ORX98720.1 - 4.6e-263 873.9 6.9 5.2e-263 873.7 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX98720.1 - 1.8e-16 59.9 0.1 3.1e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORX98720.1 - 0.0044 16.8 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORX98720.1 - 0.0084 15.4 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORX98720.1 - 0.017 14.7 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutS_III PF05192.18 ORX98720.1 - 0.044 14.0 4.9 0.42 10.8 0.8 2.4 2 1 0 2 2 2 0 MutS domain III DUF3849 PF12960.7 ORX98720.1 - 0.047 13.7 0.5 0.1 12.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DDR PF08841.10 ORX98720.1 - 0.081 11.9 0.2 0.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 ORX98720.1 - 0.13 11.4 0.7 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 StbA protein Golgin_A5 PF09787.9 ORX98720.1 - 8.9 5.7 9.1 2.3 7.6 5.2 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 MetallophosC PF16370.5 ORX98738.1 - 0.011 16.0 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase zf-H2C2_2 PF13465.6 ORX98738.1 - 0.1 13.1 0.5 0.1 13.1 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 ORX98738.1 - 0.19 12.2 9.4 1.3 9.7 7.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORX98738.1 - 2.4 9.2 12.5 1.6 9.8 10.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger ubiquitin PF00240.23 ORX98739.1 - 1e-34 118.1 0.9 1.9e-34 117.2 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORX98739.1 - 2.3e-16 59.4 1.0 3.9e-16 58.6 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORX98739.1 - 9.2e-06 26.0 0.2 3.7e-05 24.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORX98739.1 - 0.00016 21.8 1.2 0.00039 20.5 0.8 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORX98739.1 - 0.0021 18.6 0.9 0.0036 17.8 0.9 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 ORX98739.1 - 0.0024 17.8 0.1 0.0045 16.9 0.1 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORX98739.1 - 0.0025 18.1 0.5 0.0057 17.0 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 ORX98739.1 - 0.011 15.8 1.2 3.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 ORX98739.1 - 0.25 9.9 2.8 5.6 5.5 0.1 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain DnaJ PF00226.31 ORX98740.1 - 2.7e-20 72.2 0.2 1.3e-19 70.1 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4917 PF16263.5 ORX98740.1 - 0.0044 16.4 0.1 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4917) Cyclin PF08613.11 ORX98741.1 - 1.5e-10 41.7 0.1 2.2e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX98741.1 - 8.7e-06 25.5 0.3 1.7e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain LAG1-DNAbind PF09271.11 ORX98743.1 - 2.6e-47 161.2 0.1 4.9e-47 160.3 0.1 1.5 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 ORX98743.1 - 5.5e-23 81.9 0.0 1.8e-12 47.8 0.0 2.6 2 0 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 ORX98743.1 - 1.7e-06 28.0 1.9 2.4e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain US30 PF17624.2 ORX98743.1 - 0.016 14.3 1.3 0.037 13.1 1.3 1.6 1 0 0 1 1 1 0 Family of unknown function SNF2_N PF00176.23 ORX98780.1 - 4.8e-11 42.0 0.1 8.5e-11 41.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Kelch_5 PF13854.6 ORX98780.1 - 0.0079 16.2 1.1 4.1 7.5 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 ORX98780.1 - 0.042 13.9 0.0 7.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 ORX98780.1 - 0.12 12.7 0.3 18 5.8 0.0 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 ORX98780.1 - 0.43 10.9 3.4 42 4.6 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain CBAH PF02275.18 ORX98781.1 - 0.015 14.9 0.2 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Helicase_C PF00271.31 ORX98782.1 - 2.6e-06 27.8 0.0 3.1e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Herpes_UL25 PF01499.16 ORX98783.1 - 0.067 11.7 1.1 0.072 11.6 1.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Sec2p PF06428.11 ORX98783.1 - 0.1 12.6 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SPOUT_MTase_2 PF14419.6 ORX98785.1 - 0.041 13.2 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Uricase PF01014.18 ORX98786.1 - 5.1e-61 204.7 5.0 1.8e-36 125.3 3.3 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORX98786.1 - 0.00084 19.9 1.1 0.016 15.8 0.7 2.3 2 0 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORX98787.1 - 1.4e-64 216.2 3.8 1.4e-36 125.6 1.5 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORX98787.1 - 0.064 13.8 0.4 0.2 12.2 0.4 1.9 1 0 0 1 1 1 0 Dihydroneopterin aldolase Glyco_hydro_129 PF11308.8 ORX98789.1 - 1.9e-119 398.6 0.0 3.5e-119 397.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GH129 GST_C_3 PF14497.6 ORX98790.1 - 4.3e-12 46.1 0.0 7.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98790.1 - 4.4e-07 30.0 0.0 7.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORX98790.1 - 2.5e-05 24.2 0.0 8.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORX98790.1 - 0.0029 17.9 0.0 0.0085 16.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORX98790.1 - 0.02 15.3 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORX98790.1 - 0.05 14.3 0.0 0.091 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain SH3_1 PF00018.28 ORX98792.1 - 6.9e-36 121.6 4.9 1.8e-11 43.5 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 ORX98792.1 - 9.6e-35 118.2 1.6 5.2e-13 48.6 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 ORX98792.1 - 5.9e-30 102.7 0.3 1.8e-08 33.9 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_4 PF06347.13 ORX98792.1 - 0.041 13.7 0.3 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain ApoC-I PF04691.12 ORX98792.1 - 0.14 12.1 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) QCR10 PF09796.9 ORX98792.1 - 0.15 12.2 0.0 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SH3_3 PF08239.11 ORX98792.1 - 0.43 10.9 6.1 3.1 8.1 0.1 2.9 3 0 0 3 3 3 0 Bacterial SH3 domain Polysacc_deac_1 PF01522.21 ORX98793.1 - 7.1e-31 106.7 0.0 1.4e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98793.1 - 6.2e-16 58.6 28.5 6.1e-08 33.0 9.6 2.5 2 0 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.15 ORX98793.1 - 0.00011 21.6 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORX98793.1 - 0.00024 20.8 0.1 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) YabA PF06156.13 ORX98793.1 - 0.018 15.7 0.1 0.22 12.2 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX98794.1 - 1e-27 96.5 0.0 1.9e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98794.1 - 4.6e-17 62.2 34.2 1.2e-08 35.3 16.5 2.4 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 ORX98794.1 - 0.00042 20.0 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) YabA PF06156.13 ORX98794.1 - 0.015 16.0 0.1 0.15 12.7 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX98795.1 - 2e-32 111.7 0.0 3.5e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98795.1 - 2.7e-17 62.9 35.1 1.7e-08 34.8 15.9 2.4 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 ORX98795.1 - 2.4e-05 24.1 0.1 4.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX98795.1 - 0.00034 19.9 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 YabA PF06156.13 ORX98795.1 - 0.011 16.4 0.1 0.17 12.5 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX98796.1 - 2.1e-32 111.6 0.0 3.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98796.1 - 2.7e-17 62.9 35.1 1.7e-08 34.8 15.9 2.4 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 ORX98796.1 - 2.5e-05 24.0 0.1 4.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX98796.1 - 0.00036 19.9 0.0 0.00047 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 YabA PF06156.13 ORX98796.1 - 0.012 16.2 0.1 0.19 12.4 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX98797.1 - 2.8e-32 111.2 0.0 4.8e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98797.1 - 1.2e-17 64.0 34.2 5.8e-09 36.3 16.2 2.4 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 ORX98797.1 - 4.4e-05 23.3 0.1 7.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX98797.1 - 0.00037 19.8 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 YabA PF06156.13 ORX98797.1 - 0.01 16.5 0.1 0.16 12.7 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX98798.1 - 4.1e-32 110.7 0.0 7.2e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98798.1 - 1.2e-17 64.0 34.2 5.8e-09 36.3 16.2 2.4 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 ORX98798.1 - 4.4e-05 23.2 0.1 7.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX98798.1 - 0.00038 19.8 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 YabA PF06156.13 ORX98798.1 - 0.011 16.4 0.1 0.17 12.6 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Polysacc_deac_1 PF01522.21 ORX98799.1 - 2.8e-32 111.2 0.0 4.8e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORX98799.1 - 8.2e-18 64.6 34.6 5.8e-09 36.3 16.2 2.4 2 0 0 2 2 2 2 Chitin recognition protein DUF2334 PF10096.9 ORX98799.1 - 4.4e-05 23.2 0.1 7.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORX98799.1 - 0.00037 19.8 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 YabA PF06156.13 ORX98799.1 - 0.01 16.5 0.1 0.15 12.7 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA SH3_1 PF00018.28 ORX98800.1 - 3.7e-21 74.5 2.6 8.3e-10 38.1 0.5 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORX98800.1 - 1.2e-18 66.7 2.5 1.5e-11 44.0 0.7 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORX98800.1 - 1.4e-13 50.3 0.0 2.2e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 ORX98800.1 - 0.00035 20.5 0.0 0.0012 18.7 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand NPV_P10 PF05531.12 ORX98800.1 - 2.2 8.8 5.3 4.4 7.8 0.3 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GDPD PF03009.17 ORX98801.1 - 4.5e-31 108.5 0.0 6e-29 101.5 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.18 ORX98802.1 - 7.3e-34 117.0 0.6 1.4e-33 116.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX98802.1 - 2.8e-07 30.6 5.7 4.4e-07 29.9 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 ORX98803.1 - 1.6e-23 84.1 2.4 1.6e-23 84.1 2.4 3.5 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SANT_DAMP1_like PF16282.5 ORX98803.1 - 0.0034 17.6 0.8 0.0052 16.9 0.8 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 PEX11 PF05648.14 ORX98803.1 - 0.02 14.3 0.1 0.02 14.3 0.1 1.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) SLATT_6 PF18169.1 ORX98803.1 - 0.34 10.5 1.0 0.8 9.3 0.6 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Snurportin1 PF11538.8 ORX98803.1 - 3.5 7.9 10.4 4.5 7.5 8.1 2.3 2 0 0 2 2 2 0 Snurportin1 tRNA_int_endo PF01974.17 ORX98804.1 - 3e-18 65.7 0.1 6.1e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Synaphin PF05835.12 ORX98804.1 - 0.028 14.7 7.4 0.039 14.2 7.4 1.2 1 0 0 1 1 1 0 Synaphin protein LPMO_10 PF03067.15 ORX98805.1 - 4e-07 30.9 0.2 1.4e-06 29.1 0.0 2.1 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Trypan_PARP PF05887.11 ORX98805.1 - 0.00021 21.3 12.2 0.00034 20.6 12.2 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Glyco_hydro_61 PF03443.14 ORX98805.1 - 0.0039 17.2 0.1 0.035 14.1 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 COX6C PF02937.15 ORX98805.1 - 0.041 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc LPMO_10 PF03067.15 ORX98806.1 - 4e-07 30.9 0.3 1.5e-06 29.0 0.0 2.2 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Trypan_PARP PF05887.11 ORX98806.1 - 0.00041 20.3 19.1 0.00066 19.7 19.1 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Glyco_hydro_61 PF03443.14 ORX98806.1 - 0.0044 17.0 0.1 0.035 14.0 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 COX6C PF02937.15 ORX98806.1 - 0.043 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc HAT PF02184.16 ORX98807.1 - 2.2e-30 104.3 73.7 3e-18 65.5 5.2 14.3 14 1 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 ORX98807.1 - 5.8e-20 70.3 15.9 0.0026 18.4 0.0 10.9 7 3 4 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORX98807.1 - 5.8e-16 58.8 0.2 0.071 13.6 0.0 7.7 6 2 1 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 ORX98807.1 - 1e-14 55.2 36.8 0.00012 22.1 1.4 7.9 2 1 5 7 7 7 6 Suppressor of forked protein (Suf) TPR_17 PF13431.6 ORX98807.1 - 1.2e-11 44.1 4.6 0.0007 19.8 0.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORX98807.1 - 8.6e-08 31.7 12.8 0.0073 15.6 1.4 5.1 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORX98807.1 - 9.3e-07 29.4 3.3 0.4 11.4 0.0 6.2 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORX98807.1 - 0.0013 18.6 18.9 4.4 7.7 0.0 9.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORX98807.1 - 0.003 18.1 15.4 19 6.1 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98807.1 - 0.0031 17.6 9.0 26 5.4 0.1 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat BSD PF03909.17 ORX98807.1 - 0.0054 16.7 0.9 0.02 14.9 0.1 2.5 2 0 0 2 2 2 1 BSD domain TPR_12 PF13424.6 ORX98807.1 - 0.017 15.4 10.1 12 6.2 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 ORX98807.1 - 0.077 13.1 0.3 0.077 13.1 0.3 8.0 6 3 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.6 ORX98807.1 - 0.19 11.9 5.3 1.6 8.9 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORX98807.1 - 0.67 9.7 3.8 0.78 9.5 0.0 3.2 4 0 0 4 4 4 0 TPR repeat c-SKI_SMAD_bind PF08782.10 ORX98807.1 - 7.4 6.9 10.3 0.7 10.2 0.7 3.7 3 1 1 4 4 4 0 c-SKI Smad4 binding domain Mur_ligase_M PF08245.12 ORX98808.1 - 5.3e-06 26.6 0.0 0.00089 19.3 0.0 2.5 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 ORX98808.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain NIF PF03031.18 ORX98809.1 - 5.8e-55 185.3 0.3 8.5e-55 184.8 0.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ATG22 PF11700.8 ORX98831.1 - 2.4e-146 488.1 23.1 2.8e-146 487.9 23.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORX98831.1 - 1.8e-08 33.7 33.8 5.1e-05 22.4 1.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TssN PF17555.2 ORX98831.1 - 0.0083 15.5 1.5 0.0083 15.5 1.5 3.1 3 0 0 3 3 3 2 Type VI secretion system, TssN PhoR PF11808.8 ORX98831.1 - 0.04 14.3 1.1 0.04 14.3 1.1 3.5 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR COG2 PF06148.11 ORX98832.1 - 0.0068 16.5 2.5 0.0093 16.1 2.5 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 MbeD_MobD PF04899.12 ORX98832.1 - 0.0097 16.0 0.7 0.13 12.4 0.7 2.3 1 1 0 1 1 1 1 MbeD/MobD like BLOC1_2 PF10046.9 ORX98832.1 - 0.017 15.4 4.9 0.034 14.5 1.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 ORX98832.1 - 0.019 15.4 2.2 0.079 13.4 2.1 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 ORX98832.1 - 0.024 14.7 1.3 0.046 13.8 1.3 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Uds1 PF15456.6 ORX98832.1 - 0.038 14.2 4.7 0.063 13.5 4.1 1.7 1 1 0 1 1 1 0 Up-regulated During Septation CheZ PF04344.13 ORX98832.1 - 0.039 13.9 1.2 0.049 13.6 1.2 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Cytochrom_B562 PF07361.11 ORX98832.1 - 0.061 14.0 1.3 0.094 13.4 1.3 1.3 1 0 0 1 1 1 0 Cytochrome b562 ACT_5 PF13710.6 ORX98832.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 ACT domain ATG16 PF08614.11 ORX98832.1 - 0.085 13.1 8.6 0.11 12.8 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 ORX98832.1 - 0.13 12.3 0.5 0.22 11.6 0.5 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_HK97_TLTM PF06120.11 ORX98832.1 - 0.37 9.9 8.5 1.1 8.4 8.4 1.7 1 1 0 1 1 1 0 Tail length tape measure protein DUF1664 PF07889.12 ORX98832.1 - 0.52 10.3 6.4 0.17 11.9 3.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORX98832.1 - 0.61 10.5 3.8 25 5.4 3.8 2.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 ORX98832.1 - 1.9 8.9 6.8 4.2 7.8 6.8 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Forkhead PF00250.18 ORX98833.1 - 4.5e-31 106.9 0.7 4.5e-31 106.9 0.7 1.6 2 0 0 2 2 2 1 Forkhead domain Linker_histone PF00538.19 ORX98833.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family Na_Ca_ex PF01699.24 ORX98834.1 - 1.6e-18 67.1 32.0 2e-13 50.6 14.5 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 ORX98834.1 - 4.4e-18 65.7 10.0 4.4e-18 65.7 10.0 3.9 4 0 0 4 4 4 1 Inner membrane component domain CCB1 PF12046.8 ORX98834.1 - 0.22 10.8 2.9 0.86 8.9 0.0 2.7 3 0 0 3 3 3 0 Cofactor assembly of complex C subunit B Nucleo_P87 PF07267.11 ORX98834.1 - 0.26 10.1 15.1 0.38 9.6 15.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.25 ORX98835.1 - 6.3e-28 97.9 0.0 7.3e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX98835.1 - 1.1e-16 60.9 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX98835.1 - 6e-09 35.2 0.1 7.3e-09 34.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORX98835.1 - 0.016 15.1 0.1 0.071 13.0 0.1 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family NDUFA12 PF05071.16 ORX98837.1 - 1.7e-12 48.0 1.0 3.1e-12 47.1 0.9 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Peptidase_M13_N PF05649.13 ORX98838.1 - 5.6e-72 243.5 0.0 7.6e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORX98838.1 - 6.8e-67 225.0 0.0 1e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 FdsD PF11390.8 ORX98838.1 - 0.11 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD zf-U1 PF06220.12 ORX98841.1 - 2.7e-14 52.6 0.9 3.5e-14 52.3 0.9 1.2 1 0 0 1 1 1 1 U1 zinc finger ALG3 PF05208.13 ORX98842.1 - 8.4e-148 492.6 25.8 1e-147 492.3 25.8 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.6 ORX98842.1 - 0.00072 19.0 22.1 0.00072 19.0 22.1 2.1 1 1 1 2 2 2 1 EpsG family SDH_alpha PF03313.15 ORX98843.1 - 9.3e-105 350.0 0.4 1.2e-104 349.6 0.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORX98843.1 - 7.5e-56 188.8 0.1 1.6e-55 187.7 0.1 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 ORX98843.1 - 0.19 10.2 1.0 0.3 9.6 1.0 1.3 1 0 0 1 1 1 0 MmgE/PrpD family SNF2_N PF00176.23 ORX98845.1 - 3e-75 253.1 2.8 6e-74 248.8 1.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORX98845.1 - 3.5e-19 69.2 0.0 1.2e-18 67.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX98845.1 - 8.9e-05 22.6 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Branch PF02485.21 ORX98845.1 - 0.0062 16.1 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 1 Core-2/I-Branching enzyme DUF4469 PF14734.6 ORX98846.1 - 0.16 12.2 0.1 14 5.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4469) with IG-like fold FAR1 PF03101.15 ORX98847.1 - 1.3e-07 32.2 3.5 2.4e-07 31.4 3.5 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain S8_pro-domain PF16470.5 ORX98847.1 - 0.024 15.4 0.1 0.35 11.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase S8 pro-domain Apolipoprotein PF01442.18 ORX98848.1 - 4.6e-06 26.7 15.6 1.2e-05 25.3 15.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORX98848.1 - 0.00015 22.2 19.8 0.092 13.4 2.5 3.1 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 ORX98848.1 - 0.013 15.6 1.5 0.013 15.6 1.5 3.8 1 1 4 5 5 5 0 Late embryogenesis abundant protein ApoLp-III PF07464.11 ORX98848.1 - 0.017 15.2 24.7 0.028 14.5 20.7 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 ORX98848.1 - 0.032 14.8 26.0 0.26 11.8 2.2 3.3 1 1 2 3 3 3 0 YtxH-like protein Mis12 PF05859.12 ORX98848.1 - 0.041 13.9 3.3 0.39 10.8 0.3 2.2 1 1 1 2 2 2 0 Mis12 protein ING PF12998.7 ORX98848.1 - 0.14 12.8 4.4 0.61 10.7 0.0 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ApoO PF09769.9 ORX98848.1 - 0.22 11.5 11.8 7 6.6 0.1 3.4 1 1 2 3 3 3 0 Apolipoprotein O Phasin PF05597.11 ORX98848.1 - 0.3 11.1 19.7 3.3 7.7 1.7 3.1 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Borrelia_P83 PF05262.11 ORX98848.1 - 0.34 9.3 20.9 0.43 9.0 20.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein KfrA_N PF11740.8 ORX98848.1 - 0.75 10.5 17.4 1.3 9.7 1.4 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term REF PF05755.12 ORX98848.1 - 0.92 9.3 14.2 3.4 7.4 4.3 2.2 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Activator-TraM PF11657.8 ORX98848.1 - 1.1 9.1 17.7 0.17 11.7 3.9 2.7 1 1 2 3 3 3 0 Transcriptional activator TraM DUF948 PF06103.11 ORX98848.1 - 2 8.7 12.4 4.5 7.6 2.7 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 ORX98848.1 - 2.5 5.9 11.8 0.048 11.6 1.3 1.9 1 1 1 2 2 2 0 Prominin Mitofilin PF09731.9 ORX98848.1 - 2.5 6.8 29.0 3 6.6 29.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DivIVA PF05103.13 ORX98848.1 - 2.9 8.0 27.5 13 5.9 16.8 2.6 1 1 1 2 2 2 0 DivIVA protein DUF4854 PF16146.5 ORX98848.1 - 3.3 8.1 11.4 1.1 9.6 0.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4854) Hamartin PF04388.12 ORX98848.1 - 3.4 6.2 16.3 3.8 6.1 16.3 1.0 1 0 0 1 1 1 0 Hamartin protein EspB PF05802.11 ORX98848.1 - 4 7.4 24.7 96 2.9 24.7 2.2 1 1 0 1 1 1 0 Enterobacterial EspB protein Forkhead PF00250.18 ORX98849.1 - 5.7e-31 106.6 1.4 6.2e-31 106.5 1.4 1.0 1 0 0 1 1 1 1 Forkhead domain START PF01852.19 ORX98850.1 - 4.1e-17 62.3 0.0 5.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 START domain START PF01852.19 ORX98851.1 - 6.6e-18 64.9 0.0 9.8e-17 61.1 0.0 2.2 1 1 0 1 1 1 1 START domain DUF4998 PF16389.5 ORX98851.1 - 0.2 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function p450 PF00067.22 ORX98854.1 - 2.2e-84 283.9 0.4 2.5e-84 283.7 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRIMA1 PF16101.5 ORX98857.1 - 5.8 7.0 10.2 0.47 10.5 5.1 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ResIII PF04851.15 ORX98858.1 - 4.7e-20 72.3 0.0 1.3e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX98858.1 - 5.4e-19 68.6 0.0 1.4e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORX98858.1 - 2.9e-14 53.2 0.0 1.8e-13 50.6 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORX98858.1 - 0.012 15.9 0.0 0.042 14.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 ORX98858.1 - 0.012 14.9 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Nucleopor_Nup85 PF07575.13 ORX98858.1 - 0.086 11.4 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin SWI2_SNF2 PF18766.1 ORX98858.1 - 0.098 12.3 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 SWI2/SNF2 ATPase RNA_pol_Rpb1_7 PF04990.12 ORX98860.1 - 0.095 12.7 0.1 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 LRR_8 PF13855.6 ORX98861.1 - 4.1e-06 26.4 5.7 4.4e-05 23.2 0.9 2.6 1 1 1 2 2 2 2 Leucine rich repeat SH3_9 PF14604.6 ORX98861.1 - 3.8e-05 23.5 0.0 9.1e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX98861.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX98861.1 - 0.0014 18.2 0.1 0.0061 16.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain G6B PF15096.6 ORX98861.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 G6B family LRRNT_2 PF08263.12 ORX98861.1 - 0.023 15.0 6.7 0.071 13.4 6.7 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Podoplanin PF05808.11 ORX98861.1 - 0.041 14.0 1.6 0.068 13.3 1.6 1.2 1 0 0 1 1 1 0 Podoplanin DUF2681 PF10883.8 ORX98861.1 - 0.14 12.6 0.2 0.22 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) LRR_4 PF12799.7 ORX98861.1 - 0.72 10.4 7.9 0.86 10.1 1.0 3.1 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) SKG6 PF08693.10 ORX98861.1 - 1.2 8.6 6.8 2.1 7.8 6.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_1 PF00560.33 ORX98861.1 - 7.4 7.6 13.3 55 4.9 0.2 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat Cupin_8 PF13621.6 ORX98862.1 - 2e-18 67.0 0.0 3.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORX98862.1 - 1.3e-17 64.2 0.0 3.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase UBA2_C PF16195.5 ORX98862.1 - 0.81 10.4 7.2 0.44 11.3 1.7 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus SR-25 PF10500.9 ORX98862.1 - 7.8 6.0 11.5 0.27 10.8 4.1 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Voltage_CLC PF00654.20 ORX98886.1 - 1.9e-51 175.4 11.3 2.4e-51 175.1 11.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 ORX98886.1 - 1.1e-09 38.6 0.0 3.8e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain Peptidase_M48_N PF16491.5 ORX98887.1 - 1.5e-57 194.5 4.4 1.5e-57 194.5 4.4 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORX98887.1 - 1.7e-32 112.8 0.0 2.5e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 ORX98887.1 - 0.0068 16.1 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) DUF2268 PF10026.9 ORX98887.1 - 0.11 12.1 0.3 0.62 9.6 0.1 2.3 3 0 0 3 3 3 0 Predicted Zn-dependent protease (DUF2268) ANAPC4 PF12896.7 ORX98889.1 - 1.3e-49 168.4 1.0 2.1e-49 167.8 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 ORX98889.1 - 1.8e-26 92.3 0.1 3.6e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 ORX98890.1 - 1.7e-39 135.1 3.9 1.7e-39 135.1 3.9 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ORX98890.1 - 0.0038 17.2 3.4 0.021 14.9 0.0 3.0 3 0 0 3 3 3 1 RING-type zinc-finger LisH PF08513.11 ORX98890.1 - 0.0058 16.6 0.3 0.025 14.6 0.0 2.2 3 0 0 3 3 3 1 LisH Syntaxin-18_N PF10496.9 ORX98890.1 - 0.029 14.6 0.3 0.087 13.1 0.3 2.0 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DnaB_2 PF07261.11 ORX98890.1 - 0.042 13.6 0.2 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Replication initiation and membrane attachment Zmiz1_N PF18028.1 ORX98890.1 - 0.087 13.1 1.6 0.84 10.0 0.1 2.6 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain Ran-binding PF05508.11 ORX98890.1 - 0.11 11.5 5.3 0.055 12.4 2.2 1.9 2 0 0 2 2 2 0 RanGTP-binding protein LZ3wCH PF18517.1 ORX98890.1 - 0.16 12.1 2.1 6 7.1 0.1 3.9 4 0 0 4 4 4 0 Leucine zipper with capping helix domain DUF3740 PF12548.8 ORX98890.1 - 1.7 9.1 10.9 2.5 8.6 1.0 3.3 2 2 1 3 3 3 0 Sulfatase protein RSS_P20 PF11757.8 ORX98890.1 - 2.7 8.5 6.3 1.6 9.2 1.1 2.7 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain PCI PF01399.27 ORX98890.1 - 3 8.4 6.2 1.6 9.3 0.1 3.2 2 1 1 3 3 3 0 PCI domain Cpn60_TCP1 PF00118.24 ORX98891.1 - 4.4e-159 530.2 4.5 5e-159 530.0 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PfkB PF00294.24 ORX98892.1 - 1.9e-42 145.7 0.0 2.2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Sec63 PF02889.16 ORX98893.1 - 2.1e-172 571.1 0.5 5.5e-94 314.1 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORX98893.1 - 8.4e-50 169.0 0.1 8.9e-27 94.0 0.2 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 ORX98893.1 - 1.5e-40 137.9 2.3 2.7e-40 137.0 0.7 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 ORX98893.1 - 8e-25 87.8 0.0 1.4e-13 51.3 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX98893.1 - 3.1e-14 53.2 0.0 2e-07 31.3 0.0 4.0 3 2 0 3 3 3 2 Helicase conserved C-terminal domain PhoH PF02562.16 ORX98893.1 - 0.00082 18.9 0.0 0.29 10.5 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein T4_baseplate PF12322.8 ORX98893.1 - 0.0076 15.7 1.9 0.0085 15.6 0.2 2.0 2 0 0 2 2 2 1 T4 bacteriophage base plate protein CopB PF05275.11 ORX98893.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) Helicase_C_2 PF13307.6 ORX98893.1 - 0.088 13.0 0.0 12 6.0 0.0 3.7 4 1 0 4 4 4 0 Helicase C-terminal domain IstB_IS21 PF01695.17 ORX98893.1 - 0.094 12.4 0.0 3.7 7.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein UNC45-central PF11701.8 ORX98894.1 - 1.1e-31 109.8 8.6 2.9e-28 98.8 0.9 4.8 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.23 ORX98894.1 - 1.2e-12 47.4 0.8 0.0032 17.5 0.0 7.6 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORX98894.1 - 1.2e-06 28.8 2.0 1.5 9.2 0.0 6.1 4 2 1 6 6 6 1 HEAT repeats DNA_alkylation PF08713.11 ORX98894.1 - 0.02 14.6 1.4 0.29 10.8 0.1 3.0 2 1 1 3 3 3 0 DNA alkylation repair enzyme RecQ_Zn_bind PF16124.5 ORX98894.1 - 0.094 13.5 1.2 2.4 9.0 0.1 3.7 3 0 0 3 3 3 0 RecQ zinc-binding HEAT_EZ PF13513.6 ORX98894.1 - 0.12 12.9 0.2 26 5.5 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat CHASE6_C PF17150.4 ORX98894.1 - 0.18 12.5 2.2 0.74 10.5 0.5 2.7 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain HEAT PF02985.22 ORX98894.1 - 0.22 11.8 5.0 23 5.6 0.0 5.8 7 0 0 7 7 7 0 HEAT repeat Metallophos PF00149.28 ORX98895.1 - 0.054 14.0 0.1 0.059 13.9 0.1 1.0 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ThiS PF02597.20 ORX98896.1 - 2.8e-14 53.5 0.0 3.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ThiS family NmrA PF05368.13 ORX98897.1 - 6.9e-18 65.0 0.0 1.1e-17 64.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORX98897.1 - 1.3e-14 54.5 0.0 2e-14 53.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding zf-C2H2 PF00096.26 ORX98898.1 - 1.5e-24 85.0 20.9 1.2e-06 28.6 0.0 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX98898.1 - 1.5e-18 66.3 20.6 1.8e-07 31.3 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX98898.1 - 2.2e-13 49.8 19.6 0.0044 17.7 0.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORX98898.1 - 5.5e-07 30.1 13.7 0.07 13.8 0.6 3.6 2 2 2 4 4 4 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORX98898.1 - 2.4e-05 24.5 5.1 0.0046 17.2 0.4 2.3 2 1 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORX98898.1 - 8.2e-05 22.5 11.5 1.5 8.9 0.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX98898.1 - 0.002 18.3 10.5 2 8.8 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORX98898.1 - 0.028 15.1 8.7 0.11 13.2 0.7 3.2 1 1 1 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORX98898.1 - 0.037 14.2 8.2 0.84 9.8 0.5 3.3 4 0 0 4 4 4 0 Aberrant zinc-finger DUF3268 PF11672.8 ORX98898.1 - 0.19 12.1 2.8 1.5 9.2 0.1 2.3 1 1 2 3 3 3 0 zinc-finger-containing domain zf-LYAR PF08790.11 ORX98898.1 - 1.9 8.5 6.3 2.6 8.0 0.1 3.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 ORX98898.1 - 3.3 7.6 20.0 5.4 6.9 0.1 4.4 4 1 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 ORX98899.1 - 1.7e-12 47.0 9.0 4.9e-07 29.9 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX98899.1 - 8.7e-10 38.6 12.1 7.2e-08 32.5 1.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX98899.1 - 8.7e-09 35.5 7.1 0.0013 19.4 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORX98899.1 - 8e-05 22.8 1.7 0.027 14.8 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORX98899.1 - 0.00022 21.1 0.6 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORX98899.1 - 0.0055 16.4 11.3 0.067 13.0 0.5 2.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORX98899.1 - 0.0061 16.5 4.1 0.044 13.8 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-TRAF PF02176.18 ORX98899.1 - 0.025 15.3 1.1 0.041 14.6 1.1 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 ORX98899.1 - 0.038 14.3 0.9 0.11 12.8 0.8 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 ORX98899.1 - 0.14 12.6 2.5 2.5 8.6 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORX98899.1 - 0.32 11.5 3.8 13 6.3 0.7 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORX98899.1 - 0.45 10.3 4.5 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type PH PF00169.29 ORX98900.1 - 1.5e-22 80.1 0.0 3.8e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 PH domain RhoGAP PF00620.27 ORX98900.1 - 1.6e-16 60.5 0.0 5.5e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain GST_N_3 PF13417.6 ORX98900.1 - 1.4e-15 57.5 0.1 5.4e-15 55.6 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORX98900.1 - 4.5e-12 46.1 0.5 1.2e-11 44.8 0.0 2.1 2 0 0 2 2 1 1 Glutathione S-transferase, N-terminal domain PX PF00787.24 ORX98900.1 - 1.6e-11 44.1 0.0 3.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 PX domain GST_N PF02798.20 ORX98900.1 - 1.2e-10 41.6 0.1 2.9e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PH_8 PF15409.6 ORX98900.1 - 2.8e-07 30.7 0.1 3e-06 27.4 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain GST_C_2 PF13410.6 ORX98900.1 - 8.2e-07 29.0 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PH_11 PF15413.6 ORX98900.1 - 6.3e-06 26.6 0.2 3.5e-05 24.2 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain GST_C_5 PF16865.5 ORX98900.1 - 0.00093 19.8 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORX98900.1 - 0.0015 18.7 0.0 0.0043 17.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORX98900.1 - 0.0057 16.8 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ING PF12998.7 ORX98901.1 - 1.3e-17 64.3 4.0 2e-17 63.6 4.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORX98901.1 - 5.4e-06 26.2 7.6 9e-06 25.5 7.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORX98901.1 - 0.0022 18.2 0.2 0.0048 17.1 0.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORX98901.1 - 0.036 14.2 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain Phage_min_cap2 PF06152.11 ORX98901.1 - 0.25 10.2 2.3 0.25 10.2 0.2 1.9 2 0 0 2 2 2 0 Phage minor capsid protein 2 SDF PF00375.18 ORX98902.1 - 3.5e-104 348.9 41.1 3.9e-104 348.8 41.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family G-alpha PF00503.20 ORX98903.1 - 6.3e-122 407.1 6.8 7.3e-122 406.9 6.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORX98903.1 - 2.5e-14 53.1 3.3 6.9e-10 38.7 0.3 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORX98903.1 - 3.5e-05 23.3 5.2 0.0021 17.5 0.1 3.1 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 ORX98903.1 - 0.0012 18.6 0.1 0.0043 16.8 0.1 2.0 2 0 0 2 2 2 1 CHC2 zinc finger KIND PF16474.5 ORX98903.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain MMR_HSR1 PF01926.23 ORX98903.1 - 0.044 13.9 0.1 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORX98903.1 - 0.074 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeS_assembly_P PF01883.19 ORX98903.1 - 0.087 13.0 0.3 0.71 10.1 0.1 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein FtsK_SpoIIIE PF01580.18 ORX98903.1 - 0.11 11.9 0.5 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Peptidase_M13 PF01431.21 ORX98904.1 - 6.3e-65 218.6 0.1 8.3e-65 218.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 ORX98904.1 - 1.4e-27 97.4 0.0 2.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 F-box-like PF12937.7 ORX98905.1 - 0.00011 22.0 0.7 0.0003 20.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like BolA PF01722.18 ORX98906.1 - 5.2e-19 68.3 0.0 9.7e-19 67.4 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein Ran_BP1 PF00638.18 ORX98907.1 - 6.6e-53 178.1 1.0 1.1e-52 177.4 1.0 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ORX98907.1 - 6.6e-06 26.0 0.5 3.3e-05 23.8 0.5 1.9 1 1 0 1 1 1 1 WH1 domain Lig_C PF18330.1 ORX98907.1 - 0.01 15.9 0.4 0.026 14.5 0.4 1.7 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region GCIP PF13324.6 ORX98907.1 - 0.05 13.2 5.0 0.07 12.7 5.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting GOLD_2 PF13897.6 ORX98907.1 - 4.9 7.6 9.3 7 7.2 5.5 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Fibrillarin PF01269.17 ORX98908.1 - 7.3e-108 358.9 0.0 9e-108 358.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORX98908.1 - 4.5e-05 23.2 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORX98908.1 - 0.0017 18.2 0.1 0.0033 17.2 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORX98908.1 - 0.15 11.7 0.0 0.55 9.8 0.0 1.8 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F EMP24_GP25L PF01105.24 ORX98909.1 - 1.8e-39 135.5 1.2 2.1e-39 135.4 1.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PHD PF00628.29 ORX98910.1 - 1.3e-08 34.5 5.8 1.3e-08 34.5 5.8 3.6 3 0 0 3 3 3 1 PHD-finger GATA PF00320.27 ORX98910.1 - 0.00028 20.4 5.6 0.00028 20.4 5.6 2.8 3 0 0 3 3 3 1 GATA zinc finger zf-PHD-like PF15446.6 ORX98910.1 - 0.001 18.7 2.6 0.001 18.7 2.6 2.7 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 ORX98910.1 - 0.026 14.4 3.9 0.026 14.4 3.9 3.6 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 ORX98910.1 - 0.03 14.4 1.1 0.11 12.6 1.1 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 ORX98910.1 - 0.036 13.6 0.7 0.036 13.6 0.7 2.6 2 0 0 2 2 2 0 PHD-finger zf-C4 PF00105.18 ORX98910.1 - 0.51 10.8 4.6 7.9 7.0 2.0 2.8 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) DNA_pol_E_B PF04042.16 ORX98911.1 - 3.3e-52 176.9 0.1 4.4e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORX98911.1 - 0.00071 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Neugrin PF06413.11 ORX98912.1 - 9.6e-13 48.7 2.2 9.6e-13 48.7 2.2 1.8 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 ORX98912.1 - 0.0058 16.8 5.1 0.0082 16.3 2.9 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Adap_comp_sub PF00928.21 ORX98913.1 - 1.2e-31 110.1 0.0 2.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORX98913.1 - 2.2e-07 30.9 0.1 3.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DCD PF06559.11 ORX98913.1 - 0.03 13.1 0.2 0.049 12.4 0.2 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF4337 PF14235.6 ORX98913.1 - 0.062 13.4 2.8 0.1 12.7 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Med22 PF06179.12 ORX98914.1 - 2.2e-23 82.4 1.8 3.1e-23 82.0 1.8 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DraK_HK_N PF18092.1 ORX98914.1 - 0.29 11.6 2.5 21 5.6 0.1 3.0 3 0 0 3 3 3 0 DraK Histidine Kinase N-terminal domain HSP70 PF00012.20 ORX98915.1 - 1.2e-265 882.3 13.1 1.4e-265 882.1 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX98915.1 - 9.9e-13 47.6 2.5 3e-10 39.5 0.9 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 ORX98915.1 - 0.0014 18.3 0.6 0.0073 16.1 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Phlebovirus_NSM PF07246.11 ORX98915.1 - 0.057 12.8 4.1 0.098 12.0 4.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DIOX_N PF14226.6 ORX98915.1 - 0.06 14.1 1.6 0.15 12.8 0.6 2.1 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal KORA PF16509.5 ORX98915.1 - 0.068 13.5 0.1 6 7.2 0.1 2.7 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor UPF0180 PF03698.13 ORX98915.1 - 0.088 13.0 0.6 0.33 11.1 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Seryl_tRNA_N PF02403.22 ORX98915.1 - 0.11 12.7 10.2 0.34 11.1 10.2 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SMBP PF16785.5 ORX98915.1 - 0.52 10.6 7.1 1.5 9.1 7.1 1.8 1 0 0 1 1 1 0 Small metal-binding protein FtsA PF14450.6 ORX98915.1 - 4.1 7.9 14.8 8.6 6.8 0.1 4.2 3 3 0 3 3 3 0 Cell division protein FtsA VCBS PF13517.6 ORX98916.1 - 2.1e-30 105.1 18.1 3.3e-09 37.2 2.2 6.2 3 3 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ORX98916.1 - 9.8e-09 35.2 25.9 0.048 13.8 0.2 7.3 7 0 0 7 7 7 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 ORX98916.1 - 0.0017 17.7 6.1 1.8 7.9 0.1 5.2 5 2 1 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region Mago_nashi PF02792.14 ORX98917.1 - 1.9e-76 255.0 0.6 2.1e-76 254.8 0.6 1.0 1 0 0 1 1 1 1 Mago nashi protein Proteasome PF00227.26 ORX98918.1 - 3.7e-45 153.7 0.0 4.2e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ubiquitin PF00240.23 ORX98919.1 - 3.6e-15 55.5 0.6 5.2e-15 55.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Blt1_C PF17183.4 ORX98919.1 - 8.8e-07 28.4 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain Rad60-SLD PF11976.8 ORX98919.1 - 7.7e-05 22.4 0.1 0.00014 21.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORX98919.1 - 0.0031 17.6 0.1 0.0095 16.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORX98919.1 - 0.0073 16.7 0.1 0.017 15.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Sec10 PF07393.11 ORX98920.1 - 1.8e-186 621.7 0.7 2.7e-186 621.1 0.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 Herpes_IE2_3 PF03361.14 ORX98920.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.8 1 1 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Laminin_II PF06009.12 ORX98920.1 - 0.93 9.5 4.1 2.3 8.2 2.9 2.4 2 0 0 2 2 2 0 Laminin Domain II Mur_ligase_M PF08245.12 ORX98921.1 - 5.2e-14 52.7 0.0 1e-13 51.7 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ORX98921.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Synaptobrevin PF00957.21 ORX98922.1 - 1.3e-31 108.3 3.1 1.5e-31 108.0 3.1 1.0 1 0 0 1 1 1 1 Synaptobrevin CD34_antigen PF06365.12 ORX98922.1 - 0.014 15.0 0.3 0.016 14.8 0.3 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family MCU PF04678.13 ORX98922.1 - 0.027 14.6 0.2 0.031 14.4 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter z-alpha PF02295.17 ORX98922.1 - 0.091 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain F-box-like PF12937.7 ORX98923.1 - 2.9e-10 39.9 3.6 2.7e-09 36.8 0.5 3.6 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 ORX98923.1 - 0.013 15.4 1.2 0.086 12.7 0.1 2.7 2 0 0 2 2 2 0 F-box domain ATP-synt_D PF01813.17 ORX98924.1 - 3.9e-72 242.2 3.0 4.8e-72 241.9 3.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Asn_synthase PF00733.21 ORX98925.1 - 1.9e-16 60.7 0.0 5.6e-10 39.4 0.1 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORX98925.1 - 3.9e-06 26.8 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORX98925.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Spo12 PF05032.12 ORX98926.1 - 1.2e-10 41.1 2.7 2.3e-10 40.2 2.7 1.5 1 0 0 1 1 1 1 Spo12 family AAA_2 PF07724.14 ORX98927.1 - 1.3e-46 158.8 5.5 1.2e-45 155.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORX98927.1 - 9.5e-35 118.7 2.8 9.5e-35 118.7 2.8 2.7 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 ORX98927.1 - 3e-24 85.9 0.1 4.5e-12 46.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORX98927.1 - 3e-23 81.7 1.6 6.7e-23 80.6 0.1 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORX98927.1 - 2.8e-17 63.0 0.2 7.7e-11 42.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORX98927.1 - 4.2e-11 43.5 4.6 6e-05 23.5 0.2 4.4 4 1 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 ORX98927.1 - 9.4e-11 41.7 0.2 4.6e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ORX98927.1 - 6.4e-08 33.0 6.5 0.011 16.1 0.0 4.9 2 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 ORX98927.1 - 1e-07 31.9 0.1 0.0024 17.6 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 ORX98927.1 - 4.1e-07 30.1 0.8 0.07 13.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 ORX98927.1 - 8.3e-06 25.4 0.0 0.022 14.3 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORX98927.1 - 1.1e-05 24.9 0.0 0.17 11.2 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORX98927.1 - 4.5e-05 24.0 1.5 0.46 11.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 ORX98927.1 - 6.1e-05 22.8 0.0 0.045 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORX98927.1 - 8e-05 23.0 0.0 0.72 10.3 0.0 3.4 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.12 ORX98927.1 - 0.00014 21.6 5.0 0.79 9.5 0.0 4.4 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 ORX98927.1 - 0.00017 21.8 0.0 0.87 9.8 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 ORX98927.1 - 0.00019 21.9 1.0 0.15 12.5 0.0 3.7 3 0 0 3 3 3 1 ABC transporter DNA_pol3_delta2 PF13177.6 ORX98927.1 - 0.00031 20.6 0.2 3.2 7.5 0.0 4.2 4 0 0 4 4 4 1 DNA polymerase III, delta subunit TsaE PF02367.17 ORX98927.1 - 0.00048 20.1 0.0 2 8.4 0.0 2.9 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 ORX98927.1 - 0.00055 19.9 5.4 0.67 9.8 0.4 4.2 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ORX98927.1 - 0.00081 19.3 0.3 0.17 11.8 0.0 3.1 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 ORX98927.1 - 0.0038 17.2 0.0 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase Bac_DnaA PF00308.18 ORX98927.1 - 0.008 16.0 0.1 3.2 7.5 0.0 2.8 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_19 PF13245.6 ORX98927.1 - 0.015 15.6 0.3 4.7 7.6 0.1 3.4 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.22 ORX98927.1 - 0.027 14.1 0.0 3.6 7.2 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 ORX98927.1 - 0.031 14.0 0.0 2.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 ORX98927.1 - 0.041 13.8 0.2 7.1 6.5 0.0 3.3 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.6 ORX98927.1 - 0.045 14.0 2.1 9.2 6.5 0.0 4.0 4 1 0 4 4 4 0 AAA domain HAUS2 PF15003.6 ORX98927.1 - 0.047 13.4 3.6 0.11 12.2 3.6 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 AAA_33 PF13671.6 ORX98927.1 - 0.055 13.6 0.6 16 5.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain Leucyl-specific PF14795.6 ORX98927.1 - 0.073 13.2 1.1 0.29 11.2 0.4 2.5 1 1 0 1 1 1 0 Leucine-tRNA synthetase-specific domain ATP_bind_1 PF03029.17 ORX98927.1 - 0.083 12.7 1.1 2.4 7.8 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Lant_dehydr_C PF14028.6 ORX98927.1 - 0.1 12.1 5.0 0.15 11.6 4.1 1.7 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term AAA_29 PF13555.6 ORX98927.1 - 0.19 11.5 0.0 26 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Syntaxin_2 PF14523.6 ORX98927.1 - 0.2 12.0 6.7 0.6 10.5 6.7 1.8 1 0 0 1 1 1 0 Syntaxin-like protein Seryl_tRNA_N PF02403.22 ORX98927.1 - 0.3 11.3 14.1 1.5 9.1 12.9 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 ORX98927.1 - 0.32 9.5 7.8 0.69 8.5 7.8 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_30 PF13604.6 ORX98927.1 - 0.82 9.4 6.4 3.9 7.2 0.3 3.7 3 2 0 3 3 3 0 AAA domain DUF1640 PF07798.11 ORX98927.1 - 0.94 9.5 10.6 2.3 8.2 10.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CENP-F_leu_zip PF10473.9 ORX98927.1 - 1.1 9.3 20.4 12 5.9 20.4 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 ORX98927.1 - 3.4 6.8 7.2 6.3 6.0 7.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.17 ORX98927.1 - 5.1 7.0 11.7 0.33 10.9 0.6 3.6 3 1 0 3 3 2 0 Prefoldin subunit YabA PF06156.13 ORX98927.1 - 7.2 7.3 9.5 26 5.5 9.5 2.0 1 0 0 1 1 1 0 Initiation control protein YabA Mito_carr PF00153.27 ORX98961.1 - 3.9e-52 174.1 0.1 3.1e-18 65.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 ORX98962.1 - 2.5e-09 36.8 0.1 5.7e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 ORX98962.1 - 2.6e-09 37.8 0.1 5.4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 ORX98962.1 - 1e-05 25.4 1.5 1e-05 25.4 1.5 2.2 2 0 0 2 2 2 1 Zinc finger domain RRM_3 PF08777.11 ORX98962.1 - 0.0026 17.8 0.2 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif zf-CCCH_3 PF15663.5 ORX98962.1 - 0.0041 17.3 0.5 0.014 15.6 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORX98962.1 - 0.0094 16.4 1.3 0.0094 16.4 1.3 2.3 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ORX98962.1 - 0.013 15.3 2.5 0.036 13.9 2.5 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 ORX98962.1 - 0.023 14.6 1.6 0.023 14.6 1.6 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.21 ORX98962.1 - 1.1 9.4 11.7 0.34 11.1 8.5 2.1 2 1 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 ORX98962.1 - 2.2 8.3 12.3 7.6 6.6 12.3 1.9 1 1 0 1 1 1 0 zinc-ribbons DnaJ_CXXCXGXG PF00684.19 ORX98962.1 - 5.3 7.5 9.8 1.1 9.7 5.2 2.2 1 1 0 1 1 1 0 DnaJ central domain Ribosomal_L29 PF00831.23 ORX98963.1 - 2.9e-21 75.2 3.4 2.9e-21 75.2 3.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 ORX98963.1 - 0.039 14.4 2.3 0.039 14.4 2.3 2.1 1 1 1 2 2 2 0 Snapin/Pallidin T3SS_needle_E PF08988.10 ORX98963.1 - 0.42 10.8 5.2 4.1 7.6 0.3 2.6 2 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Snf7 PF03357.21 ORX98963.1 - 1.3 8.6 12.6 2.5 7.7 1.0 2.1 1 1 1 2 2 2 0 Snf7 TPD52 PF04201.15 ORX98963.1 - 1.4 8.5 7.7 0.91 9.1 2.8 2.4 1 1 0 2 2 2 0 Tumour protein D52 family Prefoldin PF02996.17 ORX98963.1 - 2.5 8.1 10.6 4.9 7.1 1.8 2.9 2 1 1 3 3 3 0 Prefoldin subunit E1-E2_ATPase PF00122.20 ORX98964.1 - 2.9e-41 141.0 1.9 2.9e-41 141.0 1.9 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORX98964.1 - 5.1e-31 107.8 17.4 4.4e-27 95.0 1.4 3.2 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX98964.1 - 1.1e-23 83.1 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORX98964.1 - 2.9e-18 66.9 0.9 6.4e-18 65.8 0.9 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX98964.1 - 3.8e-10 39.3 0.1 3.3e-09 36.3 0.1 2.4 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX98964.1 - 0.01 15.6 3.5 0.021 14.6 0.3 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 ORX98964.1 - 0.1 12.9 3.4 0.38 11.1 0.0 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3043 PF11241.8 ORX98964.1 - 0.44 10.6 2.5 3.6 7.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) SBDS_C PF09377.10 ORX98965.1 - 2.3e-38 130.8 0.5 4.8e-38 129.7 0.1 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 ORX98965.1 - 1.1e-34 118.4 4.9 2e-34 117.5 4.9 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TM_PBP2_N PF16296.5 ORX98965.1 - 0.0059 16.7 0.1 1.1 9.4 0.0 2.8 2 1 1 3 3 3 1 N-terminal of TM subunit in PBP-dependent ABC transporters B2-adapt-app_C PF09066.10 ORX98965.1 - 0.033 14.3 0.8 0.93 9.6 0.1 2.3 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain ATC_hydrolase PF14196.6 ORX98965.1 - 0.06 14.1 1.6 5 7.9 1.6 2.3 1 1 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase RMMBL PF07521.12 ORX98965.1 - 0.086 12.8 0.5 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Reprolysin_5 PF13688.6 ORX98966.1 - 8.4e-44 150.1 5.0 8.4e-44 150.1 5.0 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORX98966.1 - 3.8e-43 147.7 0.8 7.5e-43 146.7 0.8 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORX98966.1 - 6.2e-43 146.8 0.3 9.7e-43 146.2 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ORX98966.1 - 5.7e-17 62.3 32.2 5.7e-17 62.3 32.2 4.6 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 ORX98966.1 - 1.8e-14 54.3 0.0 4.3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 ORX98966.1 - 4.8e-09 36.6 0.2 1.1e-05 25.7 0.1 2.4 2 0 0 2 2 2 2 Reprolysin family propeptide Reprolysin PF01421.19 ORX98966.1 - 0.0021 18.0 8.7 0.0021 18.0 8.7 2.8 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.24 ORX98966.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF2415 PF10313.9 ORX98967.1 - 1.4e-13 50.5 0.0 1.8e-12 47.0 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 ORX98967.1 - 1.7e-05 25.4 6.4 0.38 11.7 0.4 6.0 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX98967.1 - 0.00043 20.5 0.0 0.82 10.0 0.1 4.3 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX98967.1 - 0.0047 16.3 0.1 0.35 10.1 0.0 2.6 1 1 2 3 3 3 1 WD40-like domain PD40 PF07676.12 ORX98967.1 - 0.014 15.3 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORX98967.1 - 0.11 11.4 0.6 5.4 5.9 0.1 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORX98967.1 - 0.13 10.6 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Xpo1 PF08389.12 ORX98968.1 - 1.3e-23 83.7 3.8 1.6e-23 83.4 0.4 2.9 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 ORX98968.1 - 5.5e-08 32.6 0.3 2.6e-07 30.5 0.3 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 ORX98968.1 - 0.00031 20.4 0.0 0.001 18.8 0.0 1.9 1 0 0 1 1 1 1 Importin 13 repeat Peptidase_M76 PF09768.9 ORX98969.1 - 4.3e-63 212.2 5.0 4.9e-63 211.9 5.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 ORX98969.1 - 0.044 13.6 0.7 0.11 12.4 0.7 1.6 1 0 0 1 1 1 0 SprT-like family LIM PF00412.22 ORX98969.1 - 0.24 11.6 4.1 0.32 11.3 0.3 2.6 2 0 0 2 2 2 0 LIM domain DUF2012 PF09430.10 ORX98970.1 - 6.6e-27 94.1 0.0 9.4e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 ORX98970.1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 ORX98970.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II SOP4 PF17081.5 ORX98970.1 - 0.015 14.8 0.1 0.046 13.3 0.1 1.7 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein CarbopepD_reg_2 PF13715.6 ORX98970.1 - 0.057 13.4 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain HalOD1 PF18545.1 ORX98970.1 - 0.096 13.0 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 Halobacterial output domain 1 Oxysterol_BP PF01237.18 ORX98971.1 - 2.4e-88 296.5 0.2 5.1e-78 262.5 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF1279 PF06916.13 ORX98972.1 - 1.5e-20 73.5 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DTW PF03942.15 ORX98973.1 - 1.4e-41 142.4 0.1 2.3e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 DTW domain F-box-like PF12937.7 ORX98973.1 - 1.3e-09 37.8 0.4 3.2e-09 36.5 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORX98973.1 - 6.5e-05 22.8 0.1 0.00013 21.8 0.1 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORX98973.1 - 0.0001 22.1 0.4 0.00038 20.3 0.4 2.1 1 0 0 1 1 1 1 F-box domain RNA_pol_A_bac PF01000.26 ORX98974.1 - 1.9e-27 95.9 0.0 3.4e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORX98974.1 - 2.4e-21 74.9 0.0 4.6e-21 74.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain YnfE PF17452.2 ORX98974.1 - 0.051 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YnfE-like Zn_clus PF00172.18 ORX98975.1 - 1.6e-05 25.0 10.3 3.1e-05 24.0 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORX98975.1 - 0.067 13.2 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 PAS fold Meckelin PF09773.9 ORX98975.1 - 0.085 10.9 4.5 0.11 10.5 4.5 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Peptidase_C15 PF01470.17 ORX98976.1 - 2.4e-16 60.5 0.0 3.1e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 ORX98976.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 Glyco_tranf_2_3 PF13641.6 ORX98977.1 - 5e-30 105.1 0.0 6.8e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORX98977.1 - 3.7e-11 43.1 0.0 5.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX98977.1 - 7.2e-10 38.6 0.1 3.8e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 ORX98977.1 - 0.00011 22.2 7.4 0.00043 20.2 7.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 ORX98977.1 - 0.0045 15.7 0.8 0.02 13.5 0.1 2.2 2 1 0 2 2 2 1 Chitin synthase S10_plectin PF03501.15 ORX98978.1 - 2.8e-47 158.7 0.1 3.3e-47 158.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORX98978.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Kinase-like PF14531.6 ORX98978.1 - 0.059 12.7 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Replic_Relax PF13814.6 ORX98978.1 - 0.082 13.0 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation DUF4364 PF14277.6 ORX98978.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2250 PF10007.9 ORX98978.1 - 0.13 12.4 1.3 4.3 7.5 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) MT-A70 PF05063.14 ORX98979.1 - 2.2e-37 128.6 0.0 3.2e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Amidohydro_1 PF01979.20 ORX98979.1 - 6.9e-36 124.3 0.0 9.6e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORX98979.1 - 1.7e-11 44.3 0.2 1.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 ORX98979.1 - 0.01 15.6 0.2 0.04 13.7 0.2 1.9 1 1 0 1 1 1 0 Amidohydrolase TatD_DNase PF01026.21 ORX98979.1 - 0.041 13.3 0.0 0.083 12.3 0.0 1.6 1 1 0 1 1 1 0 TatD related DNase ADH_zinc_N PF00107.26 ORX98980.1 - 3.5e-07 30.3 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase eIF-5_eIF-2B PF01873.17 ORX98981.1 - 1.5e-39 134.5 0.1 2.4e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 ORX98981.1 - 5.7e-25 87.3 8.1 3.3e-24 84.8 0.4 3.4 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3080 PF11279.8 ORX98981.1 - 0.081 12.1 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DNA_RNApol_7kD PF03604.13 ORX98981.1 - 0.15 11.8 2.4 0.34 10.6 2.4 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Ada3 PF10198.9 ORX98981.1 - 2.8 8.1 5.9 1.7 8.8 1.4 2.6 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 Hist_deacetyl PF00850.19 ORX98982.1 - 4.3e-75 253.0 0.1 6.2e-75 252.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MCU PF04678.13 ORX98983.1 - 1.7e-35 122.7 0.0 2.4e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Ribosomal_L37ae PF01780.19 ORX98984.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORX98984.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORX98984.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORX98984.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORX98984.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain LRR_6 PF13516.6 ORX98985.1 - 9.2e-18 62.7 14.7 0.027 14.5 0.1 10.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 ORX98985.1 - 3.3e-17 62.3 6.3 0.0043 17.4 0.0 7.5 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORX98985.1 - 4e-08 32.7 11.0 1.2 10.0 0.1 8.5 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 ORX98985.1 - 3.2e-07 30.0 3.1 0.53 10.1 0.0 5.2 3 2 2 5 5 5 3 Leucine rich repeat Colipase-like PF15083.6 ORX98985.1 - 4.1 7.6 15.6 1.3 9.2 0.2 4.5 4 2 1 5 5 5 0 Colipase-like SH3_9 PF14604.6 ORX98986.1 - 1.5e-11 44.0 0.0 3.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORX98986.1 - 2.9e-08 33.2 1.3 5.2e-08 32.4 0.0 2.1 3 0 0 3 3 3 1 SH3 domain SKG6 PF08693.10 ORX98986.1 - 0.007 15.8 2.5 0.014 14.8 2.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 ORX98986.1 - 0.075 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Gram_pos_anchor PF00746.21 ORX98986.1 - 0.11 12.5 0.4 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif RNase_T PF00929.24 ORX98987.1 - 3.2e-25 89.6 0.0 4.6e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease TPR_1 PF00515.28 ORX98988.1 - 3.8e-24 83.5 8.5 0.00018 21.2 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORX98988.1 - 8.7e-23 78.6 10.4 0.00033 20.5 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.31 ORX98988.1 - 1.2e-22 79.8 0.5 4.5e-22 77.9 0.5 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 ORX98988.1 - 3.6e-15 56.2 3.6 0.00093 19.7 0.0 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORX98988.1 - 5.1e-15 54.9 4.9 4.6e-05 23.0 0.1 6.0 3 3 3 6 6 6 4 TPR repeat TPR_16 PF13432.6 ORX98988.1 - 8.1e-13 48.8 0.1 8.5e-06 26.3 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORX98988.1 - 8.4e-13 48.3 0.0 0.00035 20.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORX98988.1 - 5.3e-12 45.0 10.4 0.0046 17.1 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORX98988.1 - 2.8e-10 39.9 3.9 0.00037 20.7 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX98988.1 - 2.3e-09 37.3 1.7 0.69 10.9 0.0 5.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORX98988.1 - 2.8e-08 33.9 6.3 0.3 11.4 0.1 5.5 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 ORX98988.1 - 0.00033 20.9 6.8 0.15 12.4 0.0 5.1 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORX98988.1 - 0.0015 18.4 1.4 32 4.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 ORX98988.1 - 0.0024 18.0 1.8 0.059 13.6 0.0 3.4 3 1 0 3 3 3 1 MIT domain of nuclear receptor-binding factor 2 TPR_6 PF13174.6 ORX98988.1 - 0.0088 16.6 9.5 2 9.3 0.0 6.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORX98988.1 - 0.039 14.6 0.1 73 4.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 ORX98988.1 - 0.049 14.1 0.4 10 6.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 ORX98988.1 - 0.059 13.6 13.5 0.67 10.2 1.2 4.8 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 CdiI_2 PF18593.1 ORX98988.1 - 0.13 12.9 1.8 12 6.6 0.1 3.8 3 0 0 3 3 3 0 CdiI immunity protein MIT PF04212.18 ORX98988.1 - 0.55 10.3 4.5 53 4.0 0.1 4.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF357 PF04010.13 ORX98988.1 - 0.63 10.1 5.3 25 5.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF357) UQ_con PF00179.26 ORX98990.1 - 7.2e-33 113.2 0.0 8.3e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORX98990.1 - 0.0014 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORX98990.1 - 0.05 13.9 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 ORX98990.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 AAA PF00004.29 ORX98991.1 - 3.8e-39 134.1 0.0 6.9e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX98991.1 - 4.5e-11 42.4 0.0 9.9e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORX98991.1 - 3.7e-07 30.0 0.0 1.3e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORX98991.1 - 1.5e-06 28.7 0.3 2.5e-05 24.7 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORX98991.1 - 3e-06 27.3 0.1 1.3e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORX98991.1 - 6.8e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORX98991.1 - 3.4e-05 24.1 0.4 0.0043 17.3 0.0 2.6 1 1 2 3 3 2 1 AAA domain AAA_2 PF07724.14 ORX98991.1 - 4.4e-05 23.7 0.0 0.00016 21.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 ORX98991.1 - 0.00014 21.3 0.2 0.84 9.0 0.0 3.1 3 1 0 4 4 4 2 Bacterial TniB protein AAA_18 PF13238.6 ORX98991.1 - 0.00022 21.8 0.0 0.00045 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORX98991.1 - 0.00038 20.1 0.7 0.024 14.2 0.2 2.2 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX98991.1 - 0.00042 20.5 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORX98991.1 - 0.00051 19.5 0.2 0.0016 17.9 0.2 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORX98991.1 - 0.00078 19.8 0.0 0.002 18.5 0.0 1.8 1 1 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 ORX98991.1 - 0.0015 18.5 0.1 0.18 11.7 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 ORX98991.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 ORX98991.1 - 0.0018 18.4 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 ORX98991.1 - 0.0022 18.2 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORX98991.1 - 0.003 17.5 0.0 0.0083 16.1 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain DUF815 PF05673.13 ORX98991.1 - 0.0055 15.9 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 ORX98991.1 - 0.0056 17.2 0.0 0.027 15.0 0.0 2.1 2 1 0 2 2 2 1 ABC transporter NACHT PF05729.12 ORX98991.1 - 0.0059 16.5 0.1 0.013 15.4 0.1 1.6 2 0 0 2 2 1 1 NACHT domain AAA_24 PF13479.6 ORX98991.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ORX98991.1 - 0.0067 16.3 0.1 0.72 9.6 0.2 2.5 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 ORX98991.1 - 0.0074 16.7 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 ORX98991.1 - 0.0078 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein TIP49 PF06068.13 ORX98991.1 - 0.0081 15.4 0.1 0.025 13.8 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 ORX98991.1 - 0.015 14.8 0.2 0.054 13.0 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 ORX98991.1 - 0.015 15.0 0.0 0.062 13.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 ORX98991.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ORX98991.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Guanylate_kin PF00625.21 ORX98991.1 - 0.026 14.2 0.0 0.27 10.9 0.0 2.5 2 1 1 3 3 3 0 Guanylate kinase Zeta_toxin PF06414.12 ORX98991.1 - 0.03 13.6 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 ORX98991.1 - 0.044 13.1 0.2 0.89 8.9 0.0 2.2 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.17 ORX98991.1 - 0.062 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.14 ORX98991.1 - 0.15 11.2 0.2 3 7.0 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_3 PF07726.11 ORX98991.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 ORX98991.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Complex1_51K PF01512.17 ORX98992.1 - 9.8e-51 171.6 0.0 1.6e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ORX98992.1 - 4.3e-31 106.8 0.2 1.2e-30 105.4 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ORX98992.1 - 2e-08 34.0 0.0 4.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain SAPS PF04499.15 ORX98993.1 - 1.6e-121 406.5 0.2 1.4e-73 248.4 0.0 3.0 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein Nucleoporin_FG2 PF15967.5 ORX98994.1 - 4.7e-15 55.2 27.1 4.7e-15 55.2 27.1 3.0 1 1 1 2 2 2 1 Nucleoporin FG repeated region Nucleoporin_FG PF13634.6 ORX98994.1 - 5e-12 46.5 94.0 6.3e-07 30.2 20.6 3.6 2 1 1 3 3 3 3 Nucleoporin FG repeat region Synaptonemal_3 PF15191.6 ORX98994.1 - 0.026 14.3 0.1 0.079 12.7 0.0 1.8 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 Rootletin PF15035.6 ORX98994.1 - 0.2 11.7 0.4 2.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CCDC-167 PF15188.6 ORX98994.1 - 0.23 11.8 3.1 6.6 7.2 0.1 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 L51_S25_CI-B8 PF05047.16 ORX98995.1 - 1.1e-11 44.4 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AcetylCoA_hyd_C PF13336.6 ORX98996.1 - 5.3e-59 198.6 0.0 9e-59 197.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 ORX98996.1 - 2.7e-24 86.2 0.0 8.5e-24 84.6 0.0 1.8 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.22 ORX98996.1 - 0.013 15.5 0.0 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 DeoR C terminal sensor domain GCV_T_C PF08669.11 ORX98996.1 - 0.058 13.3 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain PapC_C PF13953.6 ORX98996.1 - 0.12 12.2 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 PapC C-terminal domain Hairpins PF04877.12 ORX98997.1 - 0.049 13.3 0.8 0.066 12.8 0.8 1.3 1 1 0 1 1 1 0 HrpZ V_ATPase_I PF01496.19 ORX98997.1 - 0.53 8.1 8.3 0.7 7.7 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Casc1_N PF15927.5 ORX98997.1 - 0.97 9.1 18.9 1.3 8.7 6.0 3.1 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus Occludin_ELL PF07303.13 ORX98997.1 - 2.2 9.0 12.8 2.6 8.8 1.4 3.0 1 1 2 3 3 3 0 Occludin homology domain DUF4140 PF13600.6 ORX98997.1 - 3.6 8.1 16.6 3.5 8.1 0.4 3.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) PRKG1_interact PF15898.5 ORX98997.1 - 3.7 8.5 21.4 0.096 13.6 7.0 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 ORX98997.1 - 5.3 6.3 14.2 1.2e+02 1.8 14.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 ORX98997.1 - 7 6.2 10.8 8.4 5.9 2.2 2.6 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PKcGMP_CC PF16808.5 ORX98997.1 - 8.2 6.4 16.3 9.7 6.1 1.2 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ALMT PF11744.8 ORX98997.1 - 8.4 5.1 7.7 11 4.8 7.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IF4E PF01652.18 ORX98998.1 - 1.6e-57 193.8 0.8 1.9e-57 193.5 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glycos_transf_2 PF00535.26 ORX98999.1 - 5.9e-29 101.1 0.0 7.8e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORX98999.1 - 1.2e-07 31.9 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORX98999.1 - 4.1e-05 23.2 0.0 5.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ORX98999.1 - 0.0047 17.4 0.0 0.0097 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 VHS PF00790.19 ORX99000.1 - 2e-42 144.4 0.0 4.6e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 VHS domain GGA_N-GAT PF18308.1 ORX99000.1 - 1.1e-06 28.1 0.9 1.1e-05 25.0 0.4 2.7 2 0 0 2 2 2 1 GGA N-GAT domain Mtc PF03820.17 ORX99000.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Tricarboxylate carrier CTD_bind PF04818.13 ORX99000.1 - 0.021 15.6 0.1 0.13 13.1 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Enkurin PF13864.6 ORX99000.1 - 0.095 13.1 2.6 0.21 12.0 2.6 1.6 1 0 0 1 1 1 0 Calmodulin-binding DUF2321 PF10083.9 ORX99000.1 - 0.12 12.0 0.4 4.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) CHIP_TPR_N PF18391.1 ORX99000.1 - 0.12 13.1 5.4 0.27 12.0 5.0 1.8 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Ribosomal_S30 PF04758.14 ORX99001.1 - 4.1e-29 100.6 9.6 4.4e-29 100.4 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 NDT80_PhoG PF05224.12 ORX99002.1 - 6.7e-39 134.0 0.0 1.1e-38 133.3 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AhpC-TSA PF00578.21 ORX99003.1 - 2e-36 124.7 0.0 2.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX99003.1 - 2.3e-14 53.4 0.0 2.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORX99003.1 - 6.9e-11 41.8 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ribosomal_L24e PF01246.20 ORX99004.1 - 6.5e-34 116.0 0.4 6.5e-34 116.0 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CDPS PF16715.5 ORX99004.1 - 0.58 9.8 6.9 0.87 9.2 6.9 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase DDHD PF02862.17 ORX99004.1 - 1.4 9.0 5.6 1.8 8.7 5.6 1.0 1 0 0 1 1 1 0 DDHD domain ATP-synt_E PF05680.12 ORX99004.1 - 8.7 6.8 13.6 19 5.7 11.2 2.0 1 1 1 2 2 2 0 ATP synthase E chain EMC3_TMCO1 PF01956.16 ORX99004.1 - 8.8 6.0 9.2 76 3.0 9.2 2.0 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Sel1 PF08238.12 ORX99005.1 - 6e-50 166.6 23.5 3.9e-09 36.9 0.0 8.2 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 ORX99005.1 - 0.00082 19.9 7.5 10 7.0 0.3 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX99005.1 - 0.0032 17.7 7.4 0.23 11.7 0.1 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORX99005.1 - 0.048 14.2 9.2 4.9 7.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF917 PF06032.12 ORX99005.1 - 0.13 11.1 0.1 0.46 9.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF917) TPR_14 PF13428.6 ORX99005.1 - 0.86 10.6 0.1 0.86 10.6 0.1 4.5 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORX99005.1 - 3.2 8.2 6.5 1.3e+02 3.2 0.1 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Profilin PF00235.19 ORX99006.1 - 6.3e-49 165.5 0.1 7e-49 165.3 0.1 1.0 1 0 0 1 1 1 1 Profilin Mo25 PF08569.11 ORX99007.1 - 9.5e-137 455.7 17.6 1.1e-136 455.5 17.6 1.0 1 0 0 1 1 1 1 Mo25-like AA_permease PF00324.21 ORX99008.1 - 5e-137 457.4 41.1 6e-137 457.1 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORX99008.1 - 6.7e-44 150.4 45.3 8.3e-44 150.1 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease PPR_2 PF13041.6 ORX99009.1 - 1e-29 102.4 0.0 7.9e-11 42.0 0.0 4.0 1 1 3 4 4 4 4 PPR repeat family PPR_3 PF13812.6 ORX99009.1 - 6.1e-25 87.1 0.1 4.3e-14 52.3 0.0 3.2 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 ORX99009.1 - 6.7e-20 69.9 2.5 9.3e-10 38.1 0.0 4.7 4 1 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 ORX99009.1 - 1.6e-18 66.1 0.0 1.5e-10 40.6 0.0 4.0 4 1 0 4 4 4 2 PPR repeat PPR_long PF17177.4 ORX99009.1 - 2.9e-10 39.9 0.0 4.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_4 PF07721.14 ORX99009.1 - 0.0095 16.5 0.0 0.22 12.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORX99009.1 - 0.02 15.7 0.9 3.7 8.6 0.2 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat RPM2 PF08579.11 ORX99009.1 - 0.028 14.8 0.3 1.1 9.6 0.1 3.1 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) AEP1 PF17049.5 ORX99009.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 1 1 2 2 2 0 ATPase expression protein 1 PPR_2 PF13041.6 ORX99010.1 - 5e-157 510.1 26.7 3.4e-17 62.4 0.0 15.1 2 1 14 16 16 16 15 PPR repeat family PPR_1 PF12854.7 ORX99010.1 - 8.9e-111 361.2 6.4 3.1e-11 42.8 0.0 16.3 16 0 0 16 16 16 14 PPR repeat PPR PF01535.20 ORX99010.1 - 4.8e-96 308.5 25.0 2.5e-08 33.6 0.0 15.2 15 0 0 15 15 15 15 PPR repeat PPR_3 PF13812.6 ORX99010.1 - 5.6e-90 295.4 5.3 6.1e-13 48.6 0.0 9.4 6 2 2 9 9 9 9 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX99010.1 - 1.3e-55 188.0 1.3 1.1e-13 51.1 0.0 6.8 1 1 6 7 7 7 7 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORX99010.1 - 3.1e-14 52.5 0.0 0.7 10.9 0.0 11.4 8 4 7 15 15 12 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORX99010.1 - 8.5e-14 51.2 3.5 0.092 11.6 0.0 6.7 2 1 7 9 9 9 7 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 ORX99010.1 - 1.8e-07 31.5 2.8 0.99 9.8 0.1 7.7 4 3 3 7 7 7 1 Mitochondrial ribonuclease P subunit (RPM2) Ribonuc_red_lgN PF00317.21 ORX99010.1 - 1.5e-06 28.1 5.3 7.2 6.7 0.0 7.7 1 1 3 4 4 4 1 Ribonucleotide reductase, all-alpha domain ATP13 PF12921.7 ORX99010.1 - 2.5e-06 27.3 1.0 3.7 7.4 0.0 7.3 3 3 4 7 7 7 1 Mitochondrial ATPase expression TPR_7 PF13176.6 ORX99010.1 - 6e-06 25.9 0.0 1.6 8.9 0.0 6.2 9 0 0 9 9 6 1 Tetratricopeptide repeat AEP1 PF17049.5 ORX99010.1 - 4.7e-05 22.7 0.1 7.6 5.5 0.0 5.8 2 2 4 7 7 7 1 ATPase expression protein 1 ECSIT PF06239.11 ORX99010.1 - 5.1e-05 22.5 1.1 0.36 9.9 0.0 5.3 3 2 1 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway SPOB_a PF14689.6 ORX99010.1 - 5.8e-05 22.7 0.2 0.59 9.9 0.0 5.3 5 0 0 5 5 5 1 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_2 PF07719.17 ORX99010.1 - 0.0024 17.9 0.1 38 4.7 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX99010.1 - 0.0058 16.4 0.0 18 5.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mic1 PF07035.12 ORX99010.1 - 0.0065 16.2 0.7 2.5 7.8 0.0 4.0 4 2 0 4 4 4 1 Colon cancer-associated protein Mic1-like FtsK_gamma PF09397.10 ORX99010.1 - 0.0067 16.2 1.1 4 7.3 0.0 3.9 4 0 0 4 4 4 1 Ftsk gamma domain CNOT11 PF10155.9 ORX99010.1 - 0.015 15.5 1.4 3.5 7.8 0.5 3.6 3 1 0 3 3 2 0 CCR4-NOT transcription complex subunit 11 TPR_8 PF13181.6 ORX99010.1 - 0.037 14.3 2.5 32 5.1 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DASH_Ask1 PF08655.10 ORX99010.1 - 0.048 13.6 0.1 4 7.4 0.0 3.9 4 1 1 5 5 5 0 DASH complex subunit Ask1 BRCA2 PF00634.18 ORX99010.1 - 0.15 11.8 0.1 5.3 6.8 0.0 3.2 3 0 0 3 3 3 0 BRCA2 repeat Med26 PF08711.11 ORX99011.1 - 5.4e-15 55.2 0.1 1.4e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Proteasome PF00227.26 ORX99012.1 - 2.3e-63 213.1 0.3 3.1e-63 212.7 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORX99012.1 - 7.3e-14 51.1 0.1 1.2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PUB PF09409.10 ORX99012.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 PUB domain Nitrate_red_gam PF02665.14 ORX99012.1 - 0.24 10.9 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit RNase_PH PF01138.21 ORX99013.1 - 5.8e-27 94.8 0.0 1.1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORX99013.1 - 5.1e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 UBX PF00789.20 ORX99014.1 - 5.2e-14 52.2 0.1 3.7e-13 49.5 0.0 2.4 3 0 0 3 3 3 1 UBX domain UBA_4 PF14555.6 ORX99014.1 - 2.7e-08 33.5 0.6 5.3e-08 32.6 0.6 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 ORX99014.1 - 0.065 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like m04gp34like PF12216.8 ORX99014.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Immune evasion protein TAP_C PF03943.13 ORX99014.1 - 0.096 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 TAP C-terminal domain V_ATPase_I PF01496.19 ORX99014.1 - 0.2 9.6 2.3 0.3 9.0 2.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abhydrolase_6 PF12697.7 ORX99039.1 - 5.8e-20 72.8 1.9 6.8e-20 72.6 1.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ORX99039.1 - 2.3e-08 34.1 0.1 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 ORX99039.1 - 5.2e-06 26.3 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORX99039.1 - 0.00059 19.6 0.9 0.039 13.6 0.7 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX99039.1 - 0.00071 18.9 0.3 0.19 10.9 0.3 3.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cullin PF00888.22 ORX99040.1 - 9.7e-174 579.4 24.5 5e-140 468.0 13.6 2.8 2 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.9 ORX99040.1 - 4.4e-27 93.9 5.1 2.3e-26 91.6 5.4 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4980 PF16352.5 ORX99040.1 - 0.015 15.3 0.6 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) AnfG_VnfG PF03139.15 ORX99040.1 - 0.067 13.3 0.4 0.067 13.3 0.4 2.8 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit Penicillinase_R PF03965.16 ORX99040.1 - 0.12 12.8 8.6 0.93 9.9 0.1 4.2 4 1 0 4 4 4 0 Penicillinase repressor Cullin PF00888.22 ORX99041.1 - 1.2e-120 404.0 7.5 1.5e-120 403.7 7.5 1.0 1 0 0 1 1 1 1 Cullin family PIG-X PF08320.12 ORX99042.1 - 2.1e-36 125.9 0.1 2.4e-36 125.6 0.1 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 YEATS PF03366.16 ORX99043.1 - 7.2e-35 118.8 0.8 1.2e-34 118.1 0.8 1.3 1 0 0 1 1 1 1 YEATS family RasGAP_C PF03836.15 ORX99043.1 - 0.0035 17.5 2.2 0.0056 16.8 2.2 1.3 1 0 0 1 1 1 1 RasGAP C-terminus HAUS6_N PF14661.6 ORX99043.1 - 0.079 12.5 1.5 0.15 11.6 1.3 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Ribo_biogen_C PF04034.13 ORX99044.1 - 2.6e-54 182.4 0.0 3.2e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ORX99044.1 - 2.8e-12 46.2 0.1 4.9e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Transketolase_N PF00456.21 ORX99045.1 - 3.8e-151 502.8 0.0 6.3e-151 502.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORX99045.1 - 1.5e-45 155.1 0.0 3e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORX99045.1 - 5.6e-12 45.6 0.0 1.8e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORX99045.1 - 1.6e-05 24.3 0.0 0.00062 19.1 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORX99045.1 - 0.0091 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.21 ORX99045.1 - 0.054 13.2 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Phage-tail_1 PF09097.10 ORX99045.1 - 0.069 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 DUF4355 PF14265.6 ORX99045.1 - 0.077 13.2 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) 14-3-3 PF00244.20 ORX99046.1 - 2.4e-104 347.7 6.1 2.8e-104 347.5 6.1 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 ORX99046.1 - 0.034 14.1 0.2 0.082 12.9 0.2 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Pkinase PF00069.25 ORX99048.1 - 5.8e-47 160.3 0.0 2.4e-23 82.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99048.1 - 2.5e-16 59.8 0.0 2.9e-11 43.1 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 ORX99048.1 - 0.002 18.1 0.0 0.034 14.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX99048.1 - 0.015 14.9 0.1 0.089 12.4 0.0 2.0 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORX99048.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase tRNA-synt_2b PF00587.25 ORX99049.1 - 2.9e-27 95.8 0.0 5.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORX99049.1 - 9.9e-16 57.9 6.0 2.1e-15 56.9 6.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Phe_tRNA-synt_N PF02912.18 ORX99049.1 - 0.014 15.3 4.4 0.03 14.3 4.4 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain NOC3p PF07540.11 ORX99050.1 - 4.8e-31 107.1 5.7 5.2e-31 107.0 3.4 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 ORX99050.1 - 8e-25 87.8 0.3 8e-25 87.8 0.3 2.7 3 0 0 3 3 3 1 CBF/Mak21 family Glutaredoxin2_C PF04399.13 ORX99050.1 - 0.07 13.0 4.2 0.17 11.8 0.4 3.3 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain FCH PF00611.23 ORX99050.1 - 0.67 10.3 4.2 0.7 10.2 0.3 2.9 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain PIG-Y PF15159.6 ORX99051.1 - 3.5e-20 72.7 9.0 4.4e-20 72.4 9.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y EBP PF05241.12 ORX99052.1 - 1.9e-35 121.9 12.0 2.3e-35 121.7 12.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2418 PF10332.9 ORX99052.1 - 8.3 7.0 6.6 1.4 9.5 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2418) Myb_DNA-binding PF00249.31 ORX99053.1 - 2.7e-15 56.3 0.8 5.5e-15 55.3 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX99053.1 - 7.1e-12 45.4 0.7 1.7e-11 44.2 0.7 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MscS_porin PF12795.7 ORX99053.1 - 0.23 11.0 15.7 0.39 10.2 15.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.15 ORX99053.1 - 5.7 6.4 9.5 4.2 6.9 7.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Csm1_N PF18504.1 ORX99053.1 - 6.9 7.1 16.0 4 7.9 2.9 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain Metallophos PF00149.28 ORX99054.1 - 9.5e-14 52.4 0.0 1.2e-13 52.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORX99054.1 - 4.6e-09 36.7 0.0 9e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORX99054.1 - 0.032 13.5 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Ion_trans PF00520.31 ORX99055.1 - 1.3e-123 411.0 96.9 1.4e-44 152.2 15.4 5.2 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 ORX99055.1 - 8e-06 24.8 72.7 0.00045 19.0 14.7 7.1 6 2 2 8 8 8 5 Polycystin cation channel DUF4448 PF14610.6 ORX99055.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GPHH PF16905.5 ORX99055.1 - 0.073 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated NCKAP5 PF15246.6 ORX99055.1 - 1.7 8.2 6.3 2.6 7.6 6.3 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Transketolase_N PF00456.21 ORX99058.1 - 9e-154 511.4 0.0 1.3e-153 510.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORX99058.1 - 4e-47 160.2 0.1 8.7e-47 159.1 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORX99058.1 - 9.1e-14 51.4 0.0 3.7e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORX99058.1 - 0.00054 19.3 0.0 0.0016 17.7 0.0 1.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORX99058.1 - 0.0031 16.5 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.21 ORX99058.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain TPP_enzyme_C PF02775.21 ORX99058.1 - 0.16 11.8 5.1 0.16 11.8 0.5 2.9 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain G-gamma PF00631.22 ORX99059.1 - 1.1e-17 63.7 0.2 1.3e-17 63.6 0.2 1.0 1 0 0 1 1 1 1 GGL domain MBOAT PF03062.19 ORX99060.1 - 2.2e-51 175.2 31.9 2.9e-51 174.9 31.3 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Iso_dh PF00180.20 ORX99061.1 - 4.2e-95 318.8 0.0 1.1e-94 317.4 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UPF0220 PF05255.11 ORX99062.1 - 1.3e-40 138.7 2.3 1.5e-40 138.4 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3925 PF13063.6 ORX99062.1 - 0.32 11.3 2.9 0.74 10.1 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) S-AdoMet_synt_C PF02773.16 ORX99063.1 - 6.3e-69 230.3 0.1 1.3e-68 229.3 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORX99063.1 - 6.6e-47 158.7 0.0 1.3e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORX99063.1 - 1.9e-45 153.6 0.1 4.1e-45 152.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORX99063.1 - 0.019 13.8 0.9 0.12 11.2 0.1 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Homeodomain PF00046.29 ORX99064.1 - 4e-19 68.2 2.6 7.7e-19 67.3 2.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORX99064.1 - 0.17 11.8 2.4 0.22 11.5 0.2 2.2 2 0 0 2 2 2 0 Homeobox KN domain GAS PF13851.6 ORX99064.1 - 0.35 10.2 7.0 0.55 9.6 7.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding WD40 PF00400.32 ORX99065.1 - 8.5e-20 70.7 21.7 1.1e-05 26.1 0.0 9.4 11 0 0 11 11 11 5 WD domain, G-beta repeat Nup160 PF11715.8 ORX99065.1 - 2.7 6.6 7.5 15 4.1 0.1 4.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 MDD_C PF18376.1 ORX99066.1 - 7.2e-72 241.1 0.0 1e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 ORX99066.1 - 3e-07 30.6 0.9 6.6e-07 29.5 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ribonuc_red_sm PF00268.21 ORX99067.1 - 9.3e-120 399.3 0.1 1.1e-119 399.0 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CENP-T_C PF15511.6 ORX99068.1 - 1.6e-08 34.6 0.1 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORX99068.1 - 2.5e-05 24.3 0.1 3.6e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORX99068.1 - 5.8e-05 23.5 0.2 6.6e-05 23.3 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORX99068.1 - 8.3e-05 22.9 0.1 0.00011 22.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORX99068.1 - 0.00012 22.3 0.2 0.00023 21.4 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORX99068.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORX99068.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORX99068.1 - 0.17 12.4 0.1 0.33 11.5 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HLH PF00010.26 ORX99069.1 - 1.2e-18 66.8 0.9 1.8e-18 66.2 0.1 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 ORX99069.1 - 2.6 8.2 24.2 12 6.1 0.0 3.6 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Casc1_N PF15927.5 ORX99069.1 - 4.2 7.0 14.0 0.088 12.5 1.1 2.8 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus Methyltr_RsmB-F PF01189.17 ORX99070.1 - 1.4e-37 129.3 0.0 2e-36 125.5 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORX99070.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase LPMO_10 PF03067.15 ORX99071.1 - 1.5e-05 25.8 0.2 0.00029 21.6 0.0 2.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORX99071.1 - 0.014 15.3 0.1 0.13 12.2 0.1 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 61 CBM_14 PF01607.24 ORX99071.1 - 0.56 10.4 7.4 0.46 10.7 5.3 2.1 2 1 0 2 2 2 0 Chitin binding Peritrophin-A domain MFS_1 PF07690.16 ORX99072.1 - 6e-11 41.9 31.2 6e-11 41.9 31.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX99072.1 - 5.9e-07 29.3 6.0 4.6e-06 26.4 6.0 2.4 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 Catalase PF00199.19 ORX99086.1 - 4.3e-201 668.0 0.8 5e-201 667.7 0.8 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORX99086.1 - 8e-22 77.2 0.1 1.9e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive WGR PF05406.15 ORX99088.1 - 0.48 10.5 0.1 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 WGR domain Allantoicase PF03561.15 ORX99089.1 - 1.9e-87 290.6 0.0 9.5e-45 152.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat IFT57 PF10498.9 ORX99089.1 - 0.23 10.4 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AlcCBM31 PF11606.8 ORX99091.1 - 0.95 9.7 8.7 2.9 8.1 0.2 2.8 3 0 0 3 3 3 0 Family 31 carbohydrate binding protein PTR2 PF00854.21 ORX99092.1 - 1e-79 268.3 7.4 1e-79 268.3 7.4 1.5 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 ORX99092.1 - 2.7e-15 56.2 28.0 2.7e-08 33.1 0.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Methyltransf_11 PF08241.12 ORX99093.1 - 7.2e-10 39.4 0.0 2.3e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX99093.1 - 3.1e-06 27.8 0.0 1.5e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Geminin PF07412.12 ORX99093.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Geminin RGS PF00615.19 ORX99094.1 - 1.7e-22 79.9 1.6 3e-22 79.1 1.6 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF998 PF06197.13 ORX99094.1 - 0.0058 16.2 0.8 0.0087 15.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF4223 PF13978.6 ORX99096.1 - 0.044 13.8 0.2 8 6.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) GRP PF07172.11 ORX99096.1 - 4.1 8.1 29.8 0.16 12.7 20.0 2.5 2 0 0 2 2 2 0 Glycine rich protein family E1-E2_ATPase PF00122.20 ORX99098.1 - 4.3e-28 98.1 0.2 1.8e-27 96.1 0.2 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORX99098.1 - 3.4e-10 40.6 0.1 8.8e-06 26.2 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORX99098.1 - 0.0042 16.7 1.7 0.013 15.2 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus SRP9-21 PF05486.12 ORX99099.1 - 3.3e-09 37.0 2.3 3.3e-09 37.0 2.3 2.9 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) RGS PF00615.19 ORX99100.1 - 8.6e-14 51.8 4.3 1.2e-13 51.4 4.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORX99100.1 - 9e-06 25.6 21.8 2.2e-05 24.3 20.6 2.2 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ECSCR PF15820.5 ORX99100.1 - 2.4 8.0 5.2 1.9 8.4 1.3 2.5 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Peptidase_S10 PF00450.22 ORX99101.1 - 2.4e-89 300.7 0.5 9.7e-63 213.0 0.2 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase zf-Tim10_DDP PF02953.15 ORX99103.1 - 1.3e-21 76.0 0.3 1.6e-21 75.7 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Catalase-rel PF06628.12 ORX99103.1 - 0.041 14.1 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 Catalase-related immune-responsive Acetyltransf_13 PF13880.6 ORX99104.1 - 2.7e-28 97.7 0.0 4.6e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 ORX99104.1 - 3.6e-05 23.5 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 ORX99104.1 - 0.0012 19.3 0.0 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORX99104.1 - 0.012 15.8 0.0 0.045 14.0 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family zinc_ribbon_4 PF13717.6 ORX99104.1 - 0.14 12.1 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DUF2623 PF11115.8 ORX99104.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Sugar_tr PF00083.24 ORX99105.1 - 2e-60 204.9 22.2 2.4e-60 204.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99105.1 - 6.1e-28 97.8 21.3 1.1e-27 96.9 19.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX99105.1 - 4.1e-07 29.6 2.7 8.5e-07 28.6 2.7 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORX99106.1 - 2e-60 204.9 22.2 2.4e-60 204.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99106.1 - 6.1e-28 97.8 21.3 1.1e-27 96.9 19.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORX99106.1 - 4.1e-07 29.6 2.7 8.5e-07 28.6 2.7 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB WD40 PF00400.32 ORX99107.1 - 1e-19 70.5 3.9 0.00053 20.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99107.1 - 4.4e-08 33.3 0.0 0.37 11.1 0.0 4.4 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain GspH PF12019.8 ORX99107.1 - 0.012 16.0 0.3 0.34 11.3 0.0 2.8 2 1 1 3 3 3 0 Type II transport protein GspH NAT PF04768.13 ORX99108.1 - 2.8e-43 147.5 0.1 5.5e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_1 PF00583.25 ORX99108.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CsbD PF05532.12 ORX99109.1 - 0.0069 16.3 0.1 0.0094 15.8 0.1 1.1 1 0 0 1 1 1 1 CsbD-like Fungal_trans PF04082.18 ORX99110.1 - 8.7e-36 123.3 2.0 5.3e-35 120.7 2.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX99110.1 - 7.9e-12 45.1 8.4 1.5e-11 44.2 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5102 PF17104.5 ORX99110.1 - 0.051 13.6 0.1 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) LIM PF00412.22 ORX99111.1 - 3e-19 69.0 18.4 1.9e-09 37.6 2.5 3.7 3 0 0 3 3 3 3 LIM domain zf-C3HC4_2 PF13923.6 ORX99111.1 - 6.1 6.8 13.3 1.1 9.2 0.5 4.0 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) bZIP_2 PF07716.15 ORX99112.1 - 2.1e-12 46.9 5.1 2.1e-12 46.9 5.1 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORX99112.1 - 2.1e-07 30.9 9.3 5.2e-07 29.7 9.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORX99112.1 - 4.7e-05 23.8 6.9 6.2e-05 23.4 6.2 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.13 ORX99112.1 - 0.00066 19.0 1.6 0.00077 18.8 1.6 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region APG6_N PF17675.1 ORX99112.1 - 0.0056 17.2 4.9 0.0076 16.8 4.9 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region CEP209_CC5 PF16574.5 ORX99112.1 - 0.013 15.6 2.4 0.013 15.6 2.4 1.5 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 Pox_A_type_inc PF04508.12 ORX99112.1 - 0.12 12.3 0.7 4.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Phlebovirus_NSM PF07246.11 ORX99112.1 - 0.12 11.7 4.5 0.18 11.2 4.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Hemagglutinin PF00509.18 ORX99112.1 - 0.15 10.5 0.3 0.19 10.1 0.3 1.2 1 0 0 1 1 1 0 Haemagglutinin NAM-associated PF14303.6 ORX99112.1 - 0.6 10.8 8.0 0.9 10.2 8.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CLZ PF16526.5 ORX99112.1 - 0.73 10.2 7.6 0.62 10.5 6.4 1.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 ORX99112.1 - 0.84 9.9 6.1 1.9 8.8 6.1 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain ZapB PF06005.12 ORX99112.1 - 1 9.8 10.0 1.2 9.6 9.3 1.5 1 1 0 1 1 1 0 Cell division protein ZapB DUF724 PF05266.14 ORX99112.1 - 1.3 8.8 9.0 3.8 7.3 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) RAC_head PF16717.5 ORX99113.1 - 9.9e-19 68.1 0.4 9.9e-19 68.1 0.4 3.5 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 ORX99113.1 - 5.5e-18 64.9 0.4 5.5e-18 64.9 0.4 2.8 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 ORX99113.1 - 5.9e-13 48.8 2.4 2e-07 31.1 0.5 3.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX99113.1 - 0.001 19.2 10.5 0.007 16.6 0.3 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain V_ATPase_I PF01496.19 ORX99113.1 - 7.7 4.3 15.3 13 3.5 15.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C48 PF02902.19 ORX99114.1 - 7.7e-42 143.6 0.4 8.7e-42 143.4 0.4 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 ORX99114.1 - 0.0073 16.0 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Legionella ubiquitin-specific protease A domain SAC3_GANP PF03399.16 ORX99115.1 - 1.4e-20 73.9 5.0 7.7e-14 51.8 0.6 2.1 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORX99115.1 - 0.00049 20.1 0.7 0.0017 18.3 0.1 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PixA PF12306.8 ORX99115.1 - 0.057 13.6 0.1 0.2 11.8 0.0 1.8 1 1 1 2 2 2 0 Inclusion body protein PhoD PF09423.10 ORX99117.1 - 2.4e-05 23.5 0.0 0.00076 18.6 0.0 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase COG4 PF08318.12 ORX99118.1 - 1.6e-77 260.8 1.9 3e-77 260.0 1.9 1.5 1 0 0 1 1 1 1 COG4 transport protein Vps53_N PF04100.12 ORX99118.1 - 8.1e-05 21.7 2.2 8.1e-05 21.7 2.2 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal RINT1_TIP1 PF04437.13 ORX99118.1 - 0.00056 18.9 0.2 0.00056 18.9 0.2 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Bcl-2 PF00452.19 ORX99118.1 - 0.15 12.7 0.1 1.1 9.9 0.1 2.5 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Methyltransf_23 PF13489.6 ORX99122.1 - 2.1e-29 102.5 0.0 2.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX99122.1 - 5.4e-19 68.6 0.0 8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX99122.1 - 1.5e-16 60.9 0.0 2.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX99122.1 - 2.8e-11 43.2 0.0 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORX99122.1 - 5.3e-11 43.1 0.0 9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX99122.1 - 1.5e-09 37.8 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF2194 PF09960.9 ORX99122.1 - 0.0076 14.7 0.1 0.0084 14.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) MetW PF07021.12 ORX99122.1 - 0.0089 15.6 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ORX99122.1 - 0.042 12.4 0.0 0.061 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cyclin_N PF00134.23 ORX99123.1 - 3.9e-22 78.3 0.5 3.4e-18 65.6 0.4 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORX99123.1 - 6.8e-05 22.9 0.1 0.00053 20.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 ORX99123.1 - 0.00013 21.9 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 ORX99123.1 - 0.00018 21.9 0.2 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain VOMI PF03762.17 ORX99123.1 - 0.18 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) PTR2 PF00854.21 ORX99124.1 - 3.9e-79 266.3 7.0 3.9e-79 266.3 7.0 1.6 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORX99124.1 - 2e-15 56.6 27.7 3.4e-08 32.8 11.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Dala_Dala_lig_C PF07478.13 ORX99125.1 - 1.2e-16 60.9 0.0 2.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_23 PF13489.6 ORX99125.1 - 1.7e-12 47.5 0.0 3.7e-11 43.1 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX99125.1 - 8.6e-12 45.6 0.1 3.4e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX99125.1 - 3e-11 43.8 0.0 7.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORX99125.1 - 5.4e-11 42.5 0.0 3.7e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX99125.1 - 2.1e-10 41.2 0.2 2.8e-09 37.6 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 ORX99125.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain ATP-grasp_3 PF02655.14 ORX99125.1 - 2.7e-05 24.3 0.0 9.2e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain MetW PF07021.12 ORX99125.1 - 0.00063 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ORX99125.1 - 0.00082 19.4 0.1 0.0049 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX99125.1 - 0.0012 18.2 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ATP-grasp_4 PF13535.6 ORX99125.1 - 0.0038 16.8 0.1 0.47 10.0 0.2 2.6 2 1 0 2 2 2 1 ATP-grasp domain CMAS PF02353.20 ORX99125.1 - 0.0048 16.2 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 ORX99125.1 - 0.011 15.4 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 ORX99125.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GARS_A PF01071.19 ORX99125.1 - 0.013 15.2 0.2 0.036 13.8 0.1 1.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FtsJ PF01728.19 ORX99125.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.14 ORX99125.1 - 0.1 12.0 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 ORX99125.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CPSase_L_D2 PF02786.17 ORX99125.1 - 0.12 11.9 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_YheCD PF14398.6 ORX99125.1 - 0.18 11.0 0.0 0.36 10.0 0.0 1.4 1 1 0 1 1 1 0 YheC/D like ATP-grasp RimK PF08443.11 ORX99125.1 - 0.19 11.3 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Cu-oxidase PF00394.22 ORX99152.1 - 9.9e-37 126.5 0.1 1.2e-33 116.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX99152.1 - 2.8e-34 117.7 1.5 9.9e-33 112.7 0.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX99152.1 - 2.4e-29 101.8 1.0 2.9e-26 91.8 0.0 3.9 3 1 0 3 3 3 2 Multicopper oxidase ATP-synt_C PF00137.21 ORX99153.1 - 2.6e-31 107.7 31.9 5.7e-19 68.2 10.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 ORX99153.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 Viral small hydrophobic protein NTF2 PF02136.20 ORX99154.1 - 6.6e-30 104.1 0.1 1.2e-29 103.3 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORX99154.1 - 1.7e-11 43.7 0.4 2.9e-11 43.0 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORX99154.1 - 0.0013 18.7 0.1 0.003 17.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding motif DUF4518 PF15008.6 ORX99154.1 - 0.046 12.9 0.1 0.046 12.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) SPX PF03105.19 ORX99154.1 - 0.76 9.6 12.8 1.3 8.9 12.8 1.5 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 ORX99154.1 - 1.1 9.1 27.2 1.5 8.7 27.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UTP15_C PF09384.10 ORX99155.1 - 5.1e-53 178.7 0.1 8.5e-53 178.0 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 ORX99155.1 - 3.7e-28 97.2 5.1 2.3e-08 34.6 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99155.1 - 3.5e-09 36.9 0.1 0.033 14.5 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORX99155.1 - 4e-05 22.5 0.5 0.3 9.7 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORX99155.1 - 0.0027 17.1 0.1 0.11 11.8 0.0 2.5 2 1 2 4 4 4 2 WD40-like domain MutS_III PF05192.18 ORX99155.1 - 0.041 14.1 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 MutS domain III Ribosomal_L23 PF00276.20 ORX99157.1 - 2.7e-19 69.3 0.6 4.1e-19 68.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 ER PF01133.17 ORX99159.1 - 1.9e-31 108.0 2.9 2.1e-31 107.8 2.9 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Sugar_tr PF00083.24 ORX99160.1 - 2.4e-95 320.1 21.3 2.8e-95 319.9 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99160.1 - 3.4e-32 111.8 46.7 5.1e-30 104.6 25.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TM140 PF14985.6 ORX99160.1 - 1.4 8.5 8.4 0.24 10.9 2.5 2.4 2 0 0 2 2 2 0 TM140 protein family Asp PF00026.23 ORX99161.1 - 1.6e-92 310.3 0.0 1.8e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORX99161.1 - 1.9e-13 51.0 0.3 1e-10 42.2 0.1 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORX99161.1 - 9.9e-05 22.2 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORX99161.1 - 0.12 13.0 0.1 6.1 7.6 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease DPPIV_N PF00930.21 ORX99162.1 - 1.4e-57 195.1 0.2 6.5e-56 189.6 0.1 2.4 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORX99162.1 - 3.4e-48 163.9 0.0 8.1e-48 162.7 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORX99162.1 - 5.2e-06 26.2 0.1 2.2e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORX99162.1 - 0.00018 21.2 0.1 0.0066 16.1 0.0 2.4 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 ORX99162.1 - 0.0013 18.5 0.6 0.66 9.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 ORX99162.1 - 0.0015 18.1 0.0 0.0093 15.5 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORX99162.1 - 0.0086 15.7 0.6 0.063 12.9 0.6 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORX99162.1 - 0.011 15.0 0.8 0.069 12.4 0.1 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORX99162.1 - 0.019 15.6 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 ORX99162.1 - 0.11 12.3 0.1 3.4 7.5 0.1 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SIS PF01380.22 ORX99163.1 - 2e-62 208.8 0.1 1.1e-37 128.8 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORX99163.1 - 3.2e-17 63.0 0.0 1e-16 61.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORX99163.1 - 4.6e-13 49.2 0.0 9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORX99163.1 - 0.00039 19.4 0.0 0.0006 18.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 ORX99163.1 - 0.0048 15.7 0.0 0.0097 14.7 0.1 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORX99163.1 - 0.008 16.2 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 SIS domain Ribosomal_L29 PF00831.23 ORX99164.1 - 6.1e-21 74.2 8.6 8.4e-21 73.7 3.0 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 ORX99164.1 - 0.032 14.6 3.0 0.032 14.6 3.0 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DNase-RNase PF02577.14 ORX99164.1 - 0.066 12.9 0.1 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Bifunctional nuclease T3SS_needle_E PF08988.10 ORX99164.1 - 0.2 11.8 6.4 2.6 8.2 0.1 2.7 2 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Prefoldin PF02996.17 ORX99164.1 - 1.1 9.1 9.1 1.5 8.8 2.1 2.8 2 1 1 3 3 3 0 Prefoldin subunit TPD52 PF04201.15 ORX99164.1 - 1.2 8.7 6.2 1.6 8.3 1.4 2.4 1 1 0 2 2 2 0 Tumour protein D52 family FliT PF05400.13 ORX99164.1 - 3 8.7 7.6 0.65 10.8 0.6 2.4 2 1 0 2 2 2 0 Flagellar protein FliT Snf7 PF03357.21 ORX99164.1 - 5.3 6.6 11.4 3.3 7.3 3.5 2.1 1 1 1 2 2 2 0 Snf7 zf-C3HC4_3 PF13920.6 ORX99165.1 - 4.6e-10 39.2 11.8 6.8e-10 38.6 11.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX99165.1 - 1.7e-07 31.0 15.4 2.8e-07 30.3 15.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORX99165.1 - 2.4e-07 30.6 14.5 3.8e-07 30.0 14.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORX99165.1 - 3.2e-07 30.6 14.4 5e-07 29.9 14.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORX99165.1 - 4.3e-07 29.7 15.2 6.5e-07 29.1 15.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORX99165.1 - 1.8e-05 24.5 12.4 3.2e-05 23.7 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORX99165.1 - 7.1e-05 22.7 12.6 0.00057 19.9 8.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORX99165.1 - 0.00024 21.3 8.9 0.00041 20.6 8.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORX99165.1 - 0.00032 20.5 3.5 0.00056 19.7 3.5 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 ORX99165.1 - 0.00087 19.4 13.2 0.0017 18.5 13.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORX99165.1 - 0.015 15.0 10.1 0.031 14.1 10.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Siva PF05458.12 ORX99165.1 - 0.019 14.6 5.6 0.022 14.5 4.8 1.5 1 1 0 1 1 1 0 Cd27 binding protein (Siva) zf-ANAPC11 PF12861.7 ORX99165.1 - 0.035 14.1 4.8 0.052 13.6 4.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2256 PF10013.9 ORX99165.1 - 0.043 13.9 2.7 0.12 12.5 2.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_11 PF17123.5 ORX99165.1 - 0.072 12.8 7.3 0.095 12.5 4.5 2.5 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 ORX99165.1 - 0.31 11.2 8.6 0.55 10.4 8.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Syja_N PF02383.18 ORX99166.1 - 6.4e-96 321.4 2.7 8.1e-96 321.1 2.7 1.1 1 0 0 1 1 1 1 SacI homology domain UCH PF00443.29 ORX99167.1 - 2.1e-43 148.7 0.2 3.8e-43 147.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 ORX99167.1 - 7.1e-24 83.4 10.0 1e-23 82.9 0.3 3.8 3 1 0 3 3 3 1 Variant UBP zinc finger UBA PF00627.31 ORX99167.1 - 1.1e-22 79.5 0.5 4e-10 39.4 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP PF02148.19 ORX99167.1 - 1.7e-20 73.1 11.9 3.3e-18 65.7 4.3 4.1 5 0 0 5 5 5 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORX99167.1 - 1.2e-18 67.8 19.3 1.7e-18 67.3 13.4 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Herpes_UL33 PF03581.13 ORX99167.1 - 0.11 12.9 0.1 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus UL33-like protein HEAT_2 PF13646.6 ORX99167.1 - 0.19 12.1 0.0 1.4 9.4 0.0 2.4 1 1 1 2 2 2 0 HEAT repeats RasGEF PF00617.19 ORX99169.1 - 8.8e-45 153.1 0.1 1.1e-44 152.7 0.1 1.1 1 0 0 1 1 1 1 RasGEF domain Churchill PF06573.11 ORX99170.1 - 0.012 15.9 1.2 0.012 15.9 1.2 2.1 2 1 0 2 2 2 0 Churchill protein Loricrin PF15847.5 ORX99170.1 - 0.11 11.5 15.8 0.15 11.1 15.8 1.1 1 0 0 1 1 1 0 Major keratinocyte cell envelope protein Ribosomal_L28e PF01778.17 ORX99170.1 - 0.12 13.2 0.2 0.19 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribosomal L28e protein family DUF1180 PF06679.12 ORX99170.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Ammonium_transp PF00909.21 ORX99171.1 - 4.1e-111 371.5 22.2 5.5e-111 371.1 22.2 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family CSN8_PSD8_EIF3K PF10075.9 ORX99171.1 - 6.9e-22 78.0 0.1 1.2e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 ORX99171.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 PCI domain DUF2749 PF10907.8 ORX99171.1 - 0.16 12.1 0.9 0.45 10.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PPR_2 PF13041.6 ORX99172.1 - 2.5e-37 126.8 4.2 2.2e-14 53.4 0.0 6.4 3 2 4 7 7 7 5 PPR repeat family PPR_3 PF13812.6 ORX99172.1 - 2e-32 111.1 7.1 4.1e-13 49.2 0.0 5.4 2 2 2 5 5 5 5 Pentatricopeptide repeat domain PPR PF01535.20 ORX99172.1 - 3.1e-23 80.3 9.1 4.1e-07 29.8 0.1 7.0 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 ORX99172.1 - 2.6e-20 72.7 0.0 1.1e-12 47.8 0.0 2.5 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORX99172.1 - 3.3e-17 61.9 4.0 8.8e-07 28.5 0.0 6.6 9 0 0 9 9 9 3 PPR repeat ECSIT PF06239.11 ORX99172.1 - 4.4e-06 26.0 0.7 0.075 12.1 0.1 3.4 2 1 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway COX5A PF02284.16 ORX99172.1 - 0.00084 19.3 0.0 0.28 11.2 0.0 3.4 1 1 3 4 4 4 1 Cytochrome c oxidase subunit Va RPM2 PF08579.11 ORX99172.1 - 0.025 15.0 2.1 2.2 8.7 1.0 3.6 1 1 3 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) RabGAP-TBC PF00566.18 ORX99172.1 - 0.028 14.1 0.0 12 5.5 0.0 2.7 3 0 0 3 3 3 0 Rab-GTPase-TBC domain MRP-S27 PF10037.9 ORX99172.1 - 0.07 12.0 0.1 8.7 5.1 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 ANAPC3 PF12895.7 ORX99172.1 - 0.12 12.6 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RRM_1 PF00076.22 ORX99173.1 - 1.5e-05 24.7 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps35 PF03635.17 ORX99174.1 - 0 1060.1 10.9 0 1059.9 10.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF758 PF05527.11 ORX99174.1 - 0.038 14.0 2.0 0.061 13.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF758) SDF PF00375.18 ORX99175.1 - 1e-107 360.6 34.1 1.2e-107 360.4 34.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family HNH_4 PF13395.6 ORX99175.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease LRR_8 PF13855.6 ORX99176.1 - 1.9e-05 24.3 5.3 2.8 7.8 0.0 5.9 6 0 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 ORX99176.1 - 0.0023 18.3 15.2 0.031 14.7 0.1 6.6 8 1 0 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORX99176.1 - 0.02 14.9 7.9 0.3 11.2 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich repeat Folliculin PF11704.8 ORX99177.1 - 8.6e-55 185.5 0.0 1.3e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 ORX99177.1 - 7.9e-41 140.2 0.1 7.1e-40 137.1 0.1 2.1 1 1 0 1 1 1 1 Folliculin C-terminal domain Ham1p_like PF01725.16 ORX99178.1 - 2.1e-59 200.6 0.0 2.3e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family S1FA PF04689.13 ORX99179.1 - 0.13 12.4 0.6 0.9 9.7 0.0 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA FAD-oxidase_C PF02913.19 ORX99180.1 - 3.6e-55 187.3 0.0 4.5e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORX99180.1 - 3.1e-35 120.9 0.2 5.2e-35 120.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M24 PF00557.24 ORX99181.1 - 1.3e-22 80.5 0.1 1.7e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Mito_carr PF00153.27 ORX99182.1 - 2.6e-26 91.3 3.7 6.4e-12 45.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX99182.1 - 0.0087 15.2 0.0 0.04 13.1 0.0 1.9 2 0 0 2 2 2 1 Gammaproteobacterial serine protease DUF3482 PF11981.8 ORX99182.1 - 0.96 8.8 3.3 1.5 8.2 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) tRNA-synt_2c PF01411.19 ORX99184.1 - 2.7e-220 732.6 0.0 3.7e-220 732.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORX99184.1 - 7.6e-18 64.3 0.3 1.9e-17 63.1 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORX99184.1 - 5.9e-14 52.7 6.4 1.8e-13 51.1 6.4 1.9 1 0 0 1 1 1 1 DHHA1 domain Fzo_mitofusin PF04799.13 ORX99184.1 - 0.11 12.1 1.9 2.8 7.5 0.0 2.9 2 1 1 3 3 3 0 fzo-like conserved region DUF1664 PF07889.12 ORX99184.1 - 0.11 12.5 2.3 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L9_N PF01281.19 ORX99185.1 - 1.1e-14 53.7 0.1 1.4e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Frataxin_Cyay PF01491.16 ORX99186.1 - 2.7e-36 123.9 0.0 3e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Pkinase PF00069.25 ORX99187.1 - 2.6e-20 72.9 0.0 3.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 ORX99187.1 - 6.7e-12 45.7 1.8 1e-08 35.7 0.3 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat HEAT PF02985.22 ORX99187.1 - 2.3e-08 33.6 1.1 0.73 10.3 0.1 5.1 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.20 ORX99187.1 - 9.2e-08 31.1 2.2 1e-06 27.7 2.2 2.5 1 1 0 1 1 1 1 Adaptin N terminal region ANAPC4_WD40 PF12894.7 ORX99187.1 - 4.9e-07 30.0 0.0 0.003 17.8 0.0 4.0 3 1 1 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 ORX99187.1 - 1.7e-06 28.3 0.0 0.052 14.0 0.0 3.2 2 0 0 2 2 2 2 HEAT repeats Pkinase_Tyr PF07714.17 ORX99187.1 - 5.1e-06 26.0 0.0 9.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RTP1_C1 PF10363.9 ORX99187.1 - 9e-05 22.6 1.0 0.16 12.2 0.1 3.2 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 ORX99187.1 - 0.00017 21.7 0.1 1 9.4 0.1 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORX99187.1 - 0.0065 17.0 0.2 0.37 11.3 0.1 3.3 3 1 1 4 4 3 1 HEAT-like repeat Tti2 PF10521.9 ORX99187.1 - 0.0099 15.4 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 1 Tti2 family MMS19_C PF12460.8 ORX99187.1 - 0.055 12.6 0.1 0.055 12.6 0.1 1.6 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Kinase-like PF14531.6 ORX99187.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Nbas_N PF15492.6 ORX99187.1 - 0.17 11.2 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal STAR_dimer PF16544.5 ORX99187.1 - 0.36 10.4 1.8 23 4.7 0.0 3.2 4 0 0 4 4 4 0 Homodimerisation region of STAR domain protein Pkinase PF00069.25 ORX99188.1 - 6.1e-21 75.0 0.0 9.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 ORX99188.1 - 4.3e-12 46.4 7.7 1.4e-08 35.3 0.3 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.22 ORX99188.1 - 1.6e-08 34.1 0.1 0.035 14.3 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.17 ORX99188.1 - 1.1e-07 31.4 0.0 2.5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 ORX99188.1 - 4e-05 23.8 0.1 2.6 8.4 0.0 4.3 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Kinase-like PF14531.6 ORX99188.1 - 0.00035 20.0 0.0 0.00087 18.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 ORX99188.1 - 0.003 17.9 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats Adaptin_N PF01602.20 ORX99188.1 - 0.0038 15.9 0.3 0.0088 14.6 0.2 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Tti2 PF10521.9 ORX99188.1 - 0.048 13.2 0.3 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Tti2 family HEAT_EZ PF13513.6 ORX99188.1 - 0.12 12.9 0.1 2.5 8.7 0.1 2.6 2 0 0 2 2 2 0 HEAT-like repeat PH PF00169.29 ORX99189.1 - 8.4e-15 55.2 1.3 1.2e-09 38.6 0.4 2.6 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 ORX99189.1 - 6.5e-11 42.6 0.5 5.2e-10 39.7 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 ORX99189.1 - 0.00074 19.9 0.9 0.021 15.2 0.3 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Pox_D5 PF03288.16 ORX99189.1 - 0.012 16.0 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like GPI-anchored PF10342.9 ORX99190.1 - 1.3e-14 54.7 0.0 1.5e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORX99191.1 - 1.2e-16 61.3 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pur_ac_phosph_N PF16656.5 ORX99191.1 - 0.0051 17.3 0.1 0.0065 17.0 0.1 1.1 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Mfa_like_1 PF13149.6 ORX99191.1 - 0.089 12.8 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 Fimbrillin-like GPI-anchored PF10342.9 ORX99192.1 - 2e-16 60.5 0.0 2.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pur_ac_phosph_N PF16656.5 ORX99192.1 - 0.0086 16.6 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Hydrolase_3 PF08282.12 ORX99195.1 - 3.8e-08 33.4 0.0 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORX99195.1 - 0.0004 20.8 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX99195.1 - 0.02 15.2 0.1 0.94 9.7 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase EBP PF05241.12 ORX99196.1 - 1.8e-29 102.4 0.2 2.4e-29 102.0 0.2 1.1 1 0 0 1 1 1 1 Emopamil binding protein NAD_binding_10 PF13460.6 ORX99235.1 - 2.3e-19 70.0 0.0 3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX99235.1 - 2.5e-17 63.2 0.0 5.7e-17 62.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORX99235.1 - 1.2e-06 28.2 0.1 0.0033 16.9 0.2 2.8 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORX99235.1 - 4.9e-06 26.7 0.0 0.00048 20.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ORX99235.1 - 8.5e-05 22.8 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 ORX99235.1 - 0.0004 19.9 0.1 0.00096 18.7 0.0 1.6 1 1 0 2 2 2 1 short chain dehydrogenase PAC2 PF09754.9 ORX99235.1 - 0.0036 17.3 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 PAC2 family NAD_binding_2 PF03446.15 ORX99235.1 - 0.007 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 ORX99235.1 - 0.015 14.4 0.0 0.1 11.7 0.1 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORX99235.1 - 0.016 14.2 0.1 0.058 12.4 0.1 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORX99235.1 - 0.04 13.3 0.1 0.43 9.9 0.1 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ORX99235.1 - 0.042 14.3 0.1 0.094 13.2 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORX99235.1 - 0.14 12.8 0.0 0.64 10.6 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 ORX99235.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_L18p PF00861.22 ORX99235.1 - 0.16 12.3 0.0 8 6.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thaumatin PF00314.17 ORX99236.1 - 7.3e-70 234.9 12.2 8.4e-70 234.7 12.2 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORX99236.1 - 0.17 11.1 1.9 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Beta-1,3-glucanase zf-Mss51 PF13824.6 ORX99236.1 - 0.98 9.6 5.6 0.64 10.2 2.3 2.4 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FA_desaturase PF00487.24 ORX99237.1 - 8.7e-18 65.1 21.8 1.3e-17 64.5 21.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORX99237.1 - 2.8e-15 56.2 0.0 5.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFIID-18kDa PF02269.16 ORX99238.1 - 1.8e-32 111.2 0.2 4.8e-32 109.8 0.2 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 ORX99238.1 - 0.0095 16.0 0.2 0.054 13.6 0.0 2.4 2 1 0 2 2 2 1 hTAFII28-like protein conserved region zf-C4H2 PF10146.9 ORX99238.1 - 0.62 10.3 3.0 5.5 7.2 3.0 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein DEAD PF00270.29 ORX99239.1 - 6.2e-43 146.6 0.1 1.1e-42 145.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORX99239.1 - 2.9e-27 95.2 1.1 1e-26 93.4 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 ORX99239.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-C4H2 PF10146.9 ORX99239.1 - 4.7 7.5 15.2 9.1 6.5 15.2 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Sin_N PF04801.13 ORX99239.1 - 5 6.2 16.0 7.9 5.6 16.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Alk_phosphatase PF00245.20 ORX99240.1 - 3.7e-70 237.0 0.0 7.2e-70 236.0 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORX99240.1 - 0.0019 17.6 0.3 0.0052 16.2 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORX99240.1 - 0.0039 16.6 1.0 0.015 14.7 0.2 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ORX99240.1 - 0.0067 16.1 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase LigB PF02900.18 ORX99240.1 - 0.031 13.3 0.0 0.59 9.1 0.0 2.3 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Alk_phosphatase PF00245.20 ORX99241.1 - 4.8e-70 236.6 0.0 9.3e-70 235.7 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORX99241.1 - 0.00099 18.5 0.3 0.0048 16.3 0.1 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORX99241.1 - 0.0033 16.9 0.9 0.014 14.8 0.2 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ORX99241.1 - 0.0056 16.3 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase LigB PF02900.18 ORX99241.1 - 0.041 12.9 0.1 0.55 9.3 0.0 2.5 3 0 0 3 3 3 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Alk_phosphatase PF00245.20 ORX99242.1 - 1e-70 238.8 0.1 4.6e-70 236.7 0.0 2.0 2 1 0 2 2 2 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORX99242.1 - 0.002 17.5 0.3 0.0054 16.1 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORX99242.1 - 0.0037 16.7 1.0 0.015 14.7 0.2 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ORX99242.1 - 0.0055 16.3 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase LigB PF02900.18 ORX99242.1 - 0.032 13.3 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Alk_phosphatase PF00245.20 ORX99243.1 - 1.1e-70 238.8 0.1 4.8e-70 236.6 0.0 2.0 2 1 0 2 2 2 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORX99243.1 - 0.002 17.5 0.3 0.0054 16.1 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORX99243.1 - 0.0043 16.5 1.0 0.015 14.7 0.2 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ORX99243.1 - 0.0069 16.0 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase LigB PF02900.18 ORX99243.1 - 0.032 13.3 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase MatE PF01554.18 ORX99244.1 - 1.5e-46 158.0 35.5 2.5e-25 89.0 12.7 2.7 3 0 0 3 3 3 2 MatE PIG-L PF02585.17 ORX99245.1 - 0.039 14.6 0.5 0.069 13.8 0.5 1.5 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase adh_short PF00106.25 ORX99246.1 - 7.9e-34 116.8 0.2 1.9e-32 112.3 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORX99246.1 - 3.2e-22 79.2 0.1 4.4e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORX99246.1 - 1.4e-07 31.7 0.2 2.6e-07 30.7 0.2 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORX99246.1 - 0.051 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SAM_2 PF07647.17 ORX99247.1 - 2.7e-08 33.8 0.1 5.7e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORX99247.1 - 3.3e-05 24.2 0.1 8.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 ORX99247.1 - 0.15 12.2 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 IGR protein motif PilJ PF13675.6 ORX99247.1 - 0.2 11.7 2.4 4.6 7.3 1.9 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DNA_RNApol_7kD PF03604.13 ORX99248.1 - 3.2e-17 61.9 8.1 4e-17 61.6 8.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 ORX99248.1 - 0.0021 18.2 3.5 0.0039 17.3 3.5 1.5 1 1 0 1 1 1 1 Zinc ribbon domain TFIIS_C PF01096.18 ORX99248.1 - 0.0035 17.2 0.8 1.1 9.1 0.1 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) HypA PF01155.19 ORX99248.1 - 0.0048 16.9 0.3 0.0048 16.9 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ISL3 PF14690.6 ORX99248.1 - 0.0064 17.1 3.3 0.015 15.9 0.3 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MCM_OB PF17207.3 ORX99248.1 - 0.0072 16.2 0.3 0.0072 16.2 0.3 1.1 1 0 0 1 1 1 1 MCM OB domain DUF1451 PF07295.11 ORX99248.1 - 0.0099 15.9 0.6 0.012 15.7 0.6 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain OrfB_Zn_ribbon PF07282.11 ORX99248.1 - 0.014 15.4 0.5 0.015 15.2 0.5 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 ORX99248.1 - 0.017 15.2 1.3 0.029 14.4 1.4 1.4 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_13 PF09855.9 ORX99248.1 - 0.018 15.2 1.0 0.24 11.6 0.1 2.1 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) A2L_zn_ribbon PF08792.10 ORX99248.1 - 0.019 14.7 2.6 0.11 12.3 2.9 1.9 1 1 1 2 2 2 0 A2L zinc ribbon domain DUF35_N PF12172.8 ORX99248.1 - 0.024 14.5 2.9 0.33 10.9 0.7 2.4 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_Tnp_IS1595 PF12760.7 ORX99248.1 - 0.028 14.4 2.2 2.2 8.3 0.6 2.1 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 ORX99248.1 - 0.028 14.2 4.6 0.77 9.5 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc-ribbon_6 PF10005.9 ORX99248.1 - 0.029 15.1 0.2 0.037 14.7 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 ORX99248.1 - 0.03 14.0 1.4 0.21 11.4 0.1 2.1 1 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Sec23_Sec24 PF04810.15 ORX99248.1 - 0.043 13.9 2.6 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger UPF0547 PF10571.9 ORX99248.1 - 0.057 13.5 4.1 3 8.0 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf_UBZ PF18439.1 ORX99248.1 - 0.062 12.9 1.2 4.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF951 PF06107.11 ORX99248.1 - 0.14 12.1 2.6 0.83 9.6 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) NRDD PF13597.6 ORX99248.1 - 0.15 10.9 0.8 0.14 10.9 0.8 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Ribosomal_L37e PF01907.19 ORX99248.1 - 0.53 10.5 4.5 4.3 7.6 1.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e Zn_ribbon_recom PF13408.6 ORX99248.1 - 1.2 9.7 7.6 2.5 8.7 1.4 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-trcl PF13451.6 ORX99248.1 - 2.7 8.0 7.3 2.6 8.0 0.8 2.6 2 1 1 3 3 3 0 Probable zinc-ribbon domain Ribosomal_L23eN PF03939.13 ORX99249.1 - 7.5e-24 83.7 7.9 1.3e-23 83.0 7.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORX99249.1 - 5.4e-14 52.3 1.4 1.8e-13 50.7 0.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 ORX99249.1 - 0.022 15.1 0.3 0.027 14.7 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5451) WD40 PF00400.32 ORX99250.1 - 1.9e-24 85.5 14.2 7.7e-08 32.9 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99250.1 - 3.6e-17 62.4 1.8 6.3e-09 36.0 0.1 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX99250.1 - 7.2e-07 29.3 0.1 0.47 10.3 0.0 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.13 ORX99250.1 - 0.011 14.5 0.0 0.025 13.4 0.0 1.5 1 1 1 2 2 2 0 Vps16, N-terminal region IKI3 PF04762.12 ORX99250.1 - 0.046 11.7 3.3 0.07 11.1 0.6 2.1 2 0 0 2 2 2 0 IKI3 family GHMP_kinases_N PF00288.26 ORX99251.1 - 7.7e-15 54.9 0.2 4.4e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORX99251.1 - 1.1e-08 35.3 0.0 4.9e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal WD40 PF00400.32 ORX99252.1 - 9.3e-49 162.4 25.3 2.2e-09 37.8 0.1 11.5 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 ORX99252.1 - 2.4e-29 101.8 0.0 3.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ORX99252.1 - 7.8e-24 83.8 0.0 0.0065 16.7 0.0 9.0 3 2 8 11 11 10 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX99252.1 - 4.5e-09 36.1 0.6 0.0031 16.9 0.1 4.2 3 1 1 4 4 4 2 WD40-like domain eIF2A PF08662.11 ORX99252.1 - 1.2e-06 28.6 3.8 0.071 13.0 0.0 4.8 4 2 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORX99252.1 - 2.2e-06 26.9 0.0 1.5 7.7 0.0 5.4 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORX99252.1 - 2.5e-05 23.1 0.1 0.36 9.4 0.1 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORX99252.1 - 0.0023 16.5 0.5 4.7 5.6 0.1 3.7 3 1 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORX99252.1 - 0.0033 16.2 3.7 5.3 5.7 0.6 4.9 4 2 2 6 6 6 1 Nup133 N terminal like Coatomer_WDAD PF04053.14 ORX99252.1 - 0.01 15.0 0.3 3.5 6.6 0.1 3.3 2 1 1 3 3 3 1 Coatomer WD associated region Gmad1 PF10647.9 ORX99252.1 - 0.011 15.5 0.0 2.6 7.7 0.0 3.7 3 1 1 4 4 4 0 Lipoprotein LpqB beta-propeller domain RAB3GAP2_N PF14655.6 ORX99252.1 - 0.044 13.1 0.1 0.4 9.9 0.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MCM PF00493.23 ORX99253.1 - 1.2e-78 263.3 0.0 2.1e-74 249.4 0.0 2.2 1 1 0 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 ORX99253.1 - 6.5e-28 97.0 3.0 1.2e-27 96.2 3.0 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 ORX99253.1 - 9.1e-25 86.9 2.1 1.7e-24 86.1 2.1 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 ORX99253.1 - 5e-09 35.9 0.1 3.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORX99253.1 - 8.3e-06 25.9 0.0 2.3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORX99253.1 - 2.2e-05 24.3 0.0 5.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 ORX99253.1 - 0.0029 18.0 0.0 0.0077 16.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORX99253.1 - 0.017 15.5 0.2 0.084 13.3 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 ORX99253.1 - 0.051 13.9 0.2 3.7 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 ORX99253.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 ORX99253.1 - 0.13 12.6 0.0 0.45 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain UPF0113_N PF17833.1 ORX99254.1 - 4e-31 107.4 0.1 6.1e-31 106.8 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 ORX99254.1 - 3e-24 85.1 0.0 4.8e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain MtrG PF04210.13 ORX99254.1 - 0.041 13.7 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G HpuA PF16960.5 ORX99254.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter Cys_Met_Meta_PP PF01053.20 ORX99255.1 - 4.8e-37 127.4 0.0 6.4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORX99255.1 - 0.0022 17.3 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Spt5_N PF11942.8 ORX99255.1 - 0.059 14.4 2.3 0.16 13.0 2.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PQ-loop PF04193.14 ORX99256.1 - 1.5e-26 91.9 20.4 1.3e-17 63.3 2.7 2.8 3 0 0 3 3 3 2 PQ loop repeat Imp-YgjV PF10688.9 ORX99256.1 - 0.57 10.0 10.5 0.081 12.7 6.3 1.7 2 0 0 2 2 2 0 Bacterial inner membrane protein MFS_1 PF07690.16 ORX99257.1 - 6.7e-35 120.6 64.4 7.8e-27 94.1 37.1 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily PUF PF00806.19 ORX99258.1 - 3e-58 190.4 7.1 4.9e-08 32.2 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat UCR_TM PF02921.14 ORX99259.1 - 5.4e-12 46.0 0.7 5.4e-12 46.0 0.7 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 ORX99259.1 - 8.3e-11 41.7 0.1 1.5e-10 40.8 0.1 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain SUKH-4 PF14435.6 ORX99259.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein RRF PF01765.19 ORX99260.1 - 1e-49 168.6 10.1 1.1e-49 168.5 10.1 1.0 1 0 0 1 1 1 1 Ribosome recycling factor YtxH PF12732.7 ORX99260.1 - 0.023 15.2 6.7 0.045 14.3 6.7 1.5 1 1 0 1 1 1 0 YtxH-like protein DUF2031 PF09592.10 ORX99260.1 - 0.52 9.8 10.8 0.47 9.9 9.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) SPT16 PF08644.11 ORX99261.1 - 5.4e-57 192.2 0.0 5.4e-57 192.2 0.0 3.7 4 1 1 5 5 5 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 ORX99261.1 - 5.6e-54 182.3 0.1 1.5e-53 180.9 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 ORX99261.1 - 2.6e-28 99.1 0.0 4.8e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 ORX99261.1 - 4.2e-15 55.9 0.1 1.4e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like TIP49 PF06068.13 ORX99262.1 - 1.5e-161 537.4 1.6 2.4e-161 536.8 1.6 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORX99262.1 - 7.6e-30 102.9 1.6 2.2e-29 101.4 1.6 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORX99262.1 - 8e-09 36.0 0.3 3.4e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORX99262.1 - 2.4e-08 33.9 0.5 0.00066 19.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORX99262.1 - 1.8e-06 28.0 0.4 0.0033 17.4 0.0 2.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORX99262.1 - 5.7e-06 25.9 2.2 0.00033 20.1 0.6 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 ORX99262.1 - 1.2e-05 24.8 0.3 2.5e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 ORX99262.1 - 4e-05 24.1 0.1 0.00029 21.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORX99262.1 - 0.00011 22.5 0.3 0.082 13.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ORX99262.1 - 0.0032 17.2 0.1 3.5 7.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 ORX99262.1 - 0.0033 17.0 0.3 0.0097 15.5 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORX99262.1 - 0.0034 17.6 0.1 0.0085 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 ORX99262.1 - 0.011 16.1 8.0 0.021 15.2 3.4 3.1 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 ORX99262.1 - 0.013 14.7 0.4 2 7.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_30 PF13604.6 ORX99262.1 - 0.019 14.7 0.7 1 9.0 0.3 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORX99262.1 - 0.021 14.1 0.3 0.057 12.7 0.3 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 ORX99262.1 - 0.048 14.1 0.9 0.15 12.5 0.3 2.3 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ORX99262.1 - 0.092 12.2 0.5 0.43 10.1 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region TsaE PF02367.17 ORX99262.1 - 0.095 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 ORX99262.1 - 0.36 10.8 2.0 3.4 7.6 0.1 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit LSM14 PF12701.7 ORX99263.1 - 1.9e-32 111.2 0.1 3.5e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 ORX99263.1 - 1.7e-10 41.7 9.9 4.3e-05 24.3 2.7 2.8 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.6 ORX99263.1 - 2.5e-07 30.7 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain ATP-synt_ab PF00006.25 ORX99264.1 - 5.9e-110 366.0 0.0 8.1e-110 365.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ORX99264.1 - 1.6e-42 144.2 0.0 2.8e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ORX99264.1 - 1.5e-15 57.5 2.0 3.5e-15 56.3 2.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Complex1_LYR PF05347.15 ORX99266.1 - 2.8e-08 33.7 0.8 4.8e-08 32.9 0.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DnaJ_C PF01556.18 ORX99267.1 - 1e-39 136.0 0.2 1.4e-39 135.5 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORX99267.1 - 1.3e-25 89.3 5.7 2.2e-25 88.6 5.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORX99267.1 - 8e-12 45.3 17.5 1.4e-11 44.6 17.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORX99267.1 - 0.0067 16.4 3.1 0.0067 16.4 3.1 2.7 1 1 2 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2318 PF10080.9 ORX99267.1 - 0.54 10.4 6.4 0.76 9.9 3.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 ORX99267.1 - 5.7 7.0 10.2 8.5 6.4 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PPR_2 PF13041.6 ORX99268.1 - 9.8e-89 291.4 14.6 1.2e-13 51.0 0.0 13.5 3 2 11 14 14 14 12 PPR repeat family PPR_3 PF13812.6 ORX99268.1 - 1.5e-77 255.6 11.0 3.4e-16 59.1 0.0 9.9 5 2 4 11 11 11 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORX99268.1 - 2.1e-56 187.3 8.3 1.9e-06 27.4 0.0 12.1 12 0 0 12 12 12 9 PPR repeat PPR PF01535.20 ORX99268.1 - 1.4e-54 178.6 8.4 1.4e-06 28.1 0.0 14.0 16 0 0 16 16 14 9 PPR repeat PPR_long PF17177.4 ORX99268.1 - 1.2e-45 155.6 0.0 6e-11 42.1 0.0 5.9 1 1 5 6 6 6 6 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORX99268.1 - 1e-06 27.9 1.1 0.2 10.5 0.0 4.1 2 2 2 4 4 4 2 Mitochondrial 28S ribosomal protein S27 PYRIN PF02758.16 ORX99268.1 - 0.0035 17.4 0.1 0.43 10.7 0.0 3.3 3 0 0 3 3 3 1 PAAD/DAPIN/Pyrin domain BKACE PF05853.12 ORX99268.1 - 0.0042 16.4 0.1 1.8 7.8 0.0 4.0 3 1 0 4 4 4 1 beta-keto acid cleavage enzyme RhoGAP-FF1 PF16512.5 ORX99268.1 - 0.011 16.4 0.1 4.2 8.1 0.0 3.8 4 0 0 4 4 4 0 p190-A and -B Rho GAPs FF domain GMP_synt_C PF00958.22 ORX99268.1 - 0.08 13.0 0.0 16 5.6 0.0 3.2 3 0 0 3 3 3 0 GMP synthase C terminal domain TPR_19 PF14559.6 ORX99268.1 - 0.11 13.0 0.0 2.3 8.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat IlvC PF01450.19 ORX99268.1 - 0.12 12.6 0.0 7.3 6.9 0.0 3.5 4 0 0 4 4 4 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF489 PF04356.12 ORX99268.1 - 0.14 12.1 0.2 0.38 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Ribosomal_L11_N PF03946.14 ORX99269.1 - 1.5e-24 85.6 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORX99269.1 - 3e-17 62.9 0.2 6.2e-17 61.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribonucleas_3_3 PF14622.6 ORX99270.1 - 4e-22 78.7 0.0 6.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 ORX99270.1 - 1.7e-10 41.5 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 ORX99270.1 - 3.5e-10 40.4 0.0 7.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain DUF3083 PF11281.8 ORX99270.1 - 0.055 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Arrestin_N PF00339.29 ORX99271.1 - 3.7e-07 30.3 0.0 2.1e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX99271.1 - 7.8e-07 29.6 0.1 9.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX99271.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Lum_binding PF00677.17 ORX99272.1 - 1.4e-47 159.6 1.1 3.1e-23 81.5 1.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF452 PF04301.13 ORX99272.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF452) G-gamma PF00631.22 ORX99273.1 - 2.2e-19 69.2 0.0 2.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 GGL domain LRR_8 PF13855.6 ORX99274.1 - 6.5e-21 73.9 6.6 3.8e-07 29.8 0.0 4.3 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 ORX99274.1 - 3.1e-14 52.9 4.2 0.0049 17.2 0.0 5.1 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORX99274.1 - 1.6e-07 31.0 0.1 0.00077 19.0 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 ORX99274.1 - 0.073 13.2 5.8 19 5.6 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 ORX99274.1 - 0.85 10.4 8.7 2.7e+02 2.8 0.1 6.5 6 1 0 6 6 6 0 Leucine Rich Repeat DUF4516 PF14990.6 ORX99275.1 - 0.036 13.8 12.9 1.3e+02 2.4 0.0 8.1 10 0 0 10 10 10 0 Domain of unknown function (DUF4516) DUF1460 PF07313.12 ORX99275.1 - 6.4 6.1 10.9 77 2.6 0.2 5.1 1 1 5 6 6 6 0 Protein of unknown function (DUF1460) Nucleos_tra2_C PF07662.13 ORX99276.1 - 2.3e-71 239.9 10.9 2.3e-71 239.9 10.9 2.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORX99276.1 - 3.1e-24 85.4 5.1 3.1e-24 85.4 5.1 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORX99276.1 - 0.0011 19.2 7.2 0.0011 19.2 7.2 4.4 3 2 0 3 3 3 2 Nucleoside recognition Ycf9 PF01737.17 ORX99276.1 - 0.8 9.6 11.3 0.47 10.4 0.8 4.0 4 0 0 4 4 4 0 YCF9 Chitin_synth_1 PF01644.17 ORX99313.1 - 1.3e-28 100.0 0.1 1.5e-28 99.8 0.1 1.0 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORX99313.1 - 3.1e-12 46.2 0.1 4.6e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase N-terminal AgrD PF05931.11 ORX99313.1 - 0.048 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein Cyclin PF08613.11 ORX99314.1 - 2.7e-08 34.4 0.1 3.2e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX99314.1 - 0.00034 20.4 0.3 0.00055 19.7 0.2 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Apolipoprotein PF01442.18 ORX99315.1 - 7.1e-07 29.3 26.2 8.7e-07 29.0 26.2 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 ORX99315.1 - 4.5e-05 23.4 36.0 0.0016 18.4 3.3 4.4 2 2 2 4 4 4 4 Late embryogenesis abundant protein DUF883 PF05957.13 ORX99315.1 - 0.0047 17.5 26.9 0.084 13.5 9.4 3.1 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ORX99315.1 - 0.0065 17.0 29.7 1.8e+04 -5.6 29.7 3.2 1 1 0 1 1 1 0 YtxH-like protein Baculo_p24 PF05073.12 ORX99315.1 - 0.61 9.8 5.3 1 9.1 5.3 1.5 1 1 0 1 1 1 0 Baculovirus P24 capsid protein SmAKAP PF15127.6 ORX99315.1 - 4.2 8.6 16.6 11 7.3 1.3 2.1 1 1 1 2 2 2 0 Small membrane A-kinase anchor protein DivIVA PF05103.13 ORX99315.1 - 4.4 7.4 31.4 1.8 8.6 17.2 2.2 1 1 1 2 2 2 0 DivIVA protein CENP-H PF05837.12 ORX99315.1 - 5.3 7.5 26.0 0.31 11.5 12.2 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) MAT1 PF06391.13 ORX99315.1 - 8.4 6.2 21.5 3.5 7.4 18.2 1.8 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 PIN_8 PF18476.1 ORX99315.1 - 9 6.1 12.3 12 5.6 12.3 1.3 1 0 0 1 1 1 0 PIN like domain MscL PF01741.18 ORX99316.1 - 6.3e-29 100.7 0.2 8.2e-29 100.4 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 ORX99316.1 - 0.11 12.6 2.2 0.17 11.9 2.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon ADH_N_2 PF16884.5 ORX99317.1 - 4e-30 103.9 0.0 7e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORX99317.1 - 6.7e-23 81.1 0.0 1.2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX99317.1 - 2.7e-08 35.0 0.0 4.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Rax2 PF12768.7 ORX99318.1 - 5.7e-39 133.8 0.1 4.1e-35 121.2 0.0 4.2 2 1 1 3 3 3 2 Cortical protein marker for cell polarity SH3_1 PF00018.28 ORX99318.1 - 3e-08 33.1 0.1 1e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX99318.1 - 1.3e-07 31.4 0.0 3.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX99318.1 - 0.005 16.5 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain LapA_dom PF06305.11 ORX99318.1 - 0.038 13.8 0.8 0.078 12.8 0.8 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Bac_globin PF01152.21 ORX99319.1 - 1.8e-08 34.6 0.1 2.1e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORX99319.1 - 0.031 14.2 0.1 0.054 13.4 0.1 1.4 1 1 0 1 1 1 0 Protoglobin Lambda_CIII PF02061.16 ORX99319.1 - 0.17 12.0 0.4 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Lambda Phage CIII RdRP_4 PF02123.16 ORX99319.1 - 0.18 10.7 0.1 0.18 10.6 0.1 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Ctr PF04145.15 ORX99320.1 - 7e-23 81.9 13.3 2.8e-20 73.4 13.3 2.0 1 1 0 1 1 1 1 Ctr copper transporter family DUF2434 PF10361.9 ORX99320.1 - 0.0086 15.1 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Phage_holin_2_4 PF16082.5 ORX99320.1 - 0.08 12.7 0.8 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2207 PF09972.9 ORX99320.1 - 0.48 9.1 1.5 0.51 9.0 1.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ctr PF04145.15 ORX99321.1 - 4.6e-32 111.7 4.3 5.8e-32 111.4 4.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PrgI PF12666.7 ORX99321.1 - 0.029 15.1 1.2 0.029 15.1 1.2 1.8 2 0 0 2 2 2 0 PrgI family protein WD40 PF00400.32 ORX99322.1 - 1.9e-07 31.6 0.1 0.071 14.0 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99322.1 - 0.0001 22.5 0.0 0.0037 17.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2 PF00096.26 ORX99323.1 - 5.8e-16 58.0 14.5 1.8e-07 31.2 1.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORX99323.1 - 1e-14 54.1 12.1 7e-08 32.6 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORX99323.1 - 1.2e-10 41.3 13.2 0.00039 21.0 0.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 ORX99323.1 - 2.6e-06 27.6 5.7 0.012 16.0 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORX99323.1 - 6e-06 26.1 11.4 0.19 11.8 0.9 3.3 3 1 0 3 3 3 3 C2H2-type zinc finger zf_ZIC PF18366.1 ORX99323.1 - 0.0005 20.1 2.9 0.96 9.6 0.3 3.0 2 1 1 3 3 3 2 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 ORX99323.1 - 0.00061 20.0 3.1 1.2 9.6 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORX99323.1 - 0.0067 16.7 2.7 0.011 16.0 2.7 1.4 1 1 0 1 1 1 1 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 ORX99323.1 - 0.0087 16.2 0.7 0.0087 16.2 0.7 2.6 1 1 1 2 2 2 2 Zinc ribbon domain HypA PF01155.19 ORX99323.1 - 0.029 14.4 0.7 0.031 14.3 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 ORX99323.1 - 0.039 13.6 4.2 0.55 9.9 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-CCHC_2 PF13696.6 ORX99323.1 - 0.072 12.9 0.9 0.072 12.9 0.9 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-C2HE PF16278.5 ORX99323.1 - 0.084 13.3 12.5 0.16 12.5 1.3 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 ORX99323.1 - 0.11 12.4 4.2 2.9 7.9 0.3 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 ORX99323.1 - 0.16 12.2 9.1 1.7 8.9 3.5 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 ORX99323.1 - 0.43 10.5 0.6 0.43 10.5 0.6 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 ORX99323.1 - 1.3 9.2 4.7 17 5.6 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 ORX99323.1 - 1.4 8.8 10.2 3 7.7 0.8 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type FYVE PF01363.21 ORX99323.1 - 9.3 6.5 9.8 22 5.3 3.8 2.7 1 1 1 2 2 2 0 FYVE zinc finger RRM_1 PF00076.22 ORX99324.1 - 1.4e-45 152.9 0.7 4.8e-19 67.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORX99324.1 - 5.7e-15 54.9 0.0 0.00038 20.3 0.0 3.7 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_5 PF13893.6 ORX99324.1 - 0.0073 15.9 0.0 3.7 7.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORX99324.1 - 0.1 12.6 0.1 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Sacchrp_dh_NADP PF03435.18 ORX99325.1 - 6.6e-12 45.8 0.0 9.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORX99325.1 - 0.00085 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORX99326.1 - 4.7e-11 43.1 0.0 6.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORX99326.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Palm_thioest PF02089.15 ORX99327.1 - 0.049 13.5 0.0 0.055 13.3 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Sacchrp_dh_NADP PF03435.18 ORX99328.1 - 1.1e-11 45.2 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORX99328.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NSP2-B_epitope PF14757.6 ORX99328.1 - 0.069 12.8 0.1 0.26 10.9 0.2 1.7 1 1 1 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein HEAT PF02985.22 ORX99329.1 - 1.3e-14 53.0 0.4 0.002 18.3 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 ORX99329.1 - 3.8e-08 33.5 0.1 0.00012 22.2 0.0 2.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 ORX99329.1 - 1.6e-06 27.6 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORX99329.1 - 7.5e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 ORX99329.1 - 2e-05 24.9 0.0 0.002 18.5 0.0 2.9 1 1 3 4 4 4 3 HEAT repeats Adaptin_N PF01602.20 ORX99329.1 - 0.00055 18.6 0.5 0.0029 16.2 0.2 2.0 1 1 2 3 3 3 1 Adaptin N terminal region HEAT_EZ PF13513.6 ORX99329.1 - 0.0036 17.8 0.1 6.8 7.3 0.1 4.0 2 2 2 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 ORX99329.1 - 0.049 13.2 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 CLASP N terminal Kinase-like PF14531.6 ORX99329.1 - 0.067 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NAP PF00956.18 ORX99331.1 - 3.8e-88 295.2 8.5 5.7e-88 294.6 8.5 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Phage_Gp111 PF07410.11 ORX99331.1 - 0.089 13.3 1.0 0.18 12.3 0.2 1.9 2 0 0 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein Arrestin_C PF02752.22 ORX99333.1 - 2.2e-10 41.1 0.0 1.1e-09 38.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX99333.1 - 1.9e-06 28.0 0.0 1.2e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Isochorismatase PF00857.20 ORX99334.1 - 9.1e-30 104.1 0.0 1.5e-29 103.4 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Nramp PF01566.18 ORX99339.1 - 5.1e-120 400.7 24.3 5.1e-120 400.7 24.3 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein G_glu_transpept PF01019.21 ORX99340.1 - 3.3e-179 596.9 0.2 3.8e-179 596.7 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Rimk_N PF18030.1 ORX99340.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RimK PreATP-grasp domain zf-Tim10_DDP PF02953.15 ORX99341.1 - 2.2e-27 94.5 0.3 3.1e-27 94.0 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORX99341.1 - 0.055 13.2 1.9 0.098 12.4 1.9 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF4112 PF13430.6 ORX99342.1 - 1.8e-32 111.8 1.6 2e-32 111.6 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HAD_2 PF13419.6 ORX99344.1 - 1.2e-21 77.6 0.0 1.7e-21 77.1 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX99344.1 - 7.1e-15 55.9 0.0 9.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX99344.1 - 2.1e-07 30.9 0.1 4.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORX99344.1 - 0.00048 20.2 0.0 0.57 10.3 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase RasGEF PF00617.19 ORX99345.1 - 2.7e-49 167.7 0.1 3.4e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 RasGEF domain NAD_binding_10 PF13460.6 ORX99346.1 - 2.9e-11 43.6 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORX99346.1 - 6.1e-10 39.1 0.0 1.2e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORX99346.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORX99346.1 - 0.2 10.7 0.0 18 4.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain RtcB PF01139.17 ORX99355.1 - 9.9e-61 206.1 0.1 1.3e-48 166.2 0.1 2.4 1 1 1 2 2 2 2 tRNA-splicing ligase RtcB E1-E2_ATPase PF00122.20 ORX99356.1 - 1.5e-40 138.7 0.0 1.5e-40 138.7 0.0 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORX99356.1 - 3e-16 60.3 0.1 1.5e-15 58.1 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORX99356.1 - 3e-15 56.4 13.5 3e-15 56.4 13.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORX99356.1 - 5.8e-08 32.7 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORX99356.1 - 3e-07 30.0 0.1 7.8e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORX99356.1 - 0.0096 15.7 0.1 0.04 13.7 0.1 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase COX7C PF02935.16 ORX99356.1 - 0.037 14.3 0.8 0.16 12.3 0.8 2.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DNA_photolyase PF00875.18 ORX99356.1 - 0.068 13.2 0.2 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 DNA photolyase HAD PF12710.7 ORX99356.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Myb_DNA-bind_4 PF13837.6 ORX99357.1 - 1.3e-19 70.3 5.4 1.3e-19 70.3 5.4 2.7 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain SUIM_assoc PF16619.5 ORX99357.1 - 8.4e-08 32.2 8.4 5.6e-06 26.3 0.2 4.5 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 MADF_DNA_bdg PF10545.9 ORX99357.1 - 3e-05 24.3 3.5 3e-05 24.3 3.5 3.1 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 ORX99357.1 - 6.9e-05 23.0 2.1 0.00024 21.3 2.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX99357.1 - 0.0012 18.9 2.9 0.0023 18.1 2.9 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Med15 PF09606.10 ORX99357.1 - 0.007 15.1 39.6 0.011 14.5 39.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Myb_DNA-bind_3 PF12776.7 ORX99357.1 - 0.011 16.6 3.3 0.011 16.6 3.3 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain PepSY_TM PF03929.16 ORX99357.1 - 1.8 8.1 5.4 4 7.0 5.4 1.6 1 0 0 1 1 1 0 PepSY-associated TM region Myb_DNA-bind_5 PF13873.6 ORX99357.1 - 5.8 7.1 13.8 0.26 11.4 5.7 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain CoA_binding PF02629.19 ORX99358.1 - 1.4e-29 102.6 0.4 1.4e-29 102.6 0.4 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ORX99358.1 - 6.2e-24 84.5 0.0 1.5e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ORX99358.1 - 1.5e-06 28.0 0.0 4.5e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ORX99358.1 - 8.4e-06 26.3 0.1 3e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 ORX99358.1 - 0.024 15.5 0.1 0.21 12.4 0.0 2.5 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_transf_22 PF03901.17 ORX99359.1 - 2.1e-93 313.8 24.5 2.5e-93 313.6 24.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XRN1_D2_D3 PF18334.1 ORX99359.1 - 0.043 14.0 0.1 0.091 13.0 0.1 1.5 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D2/D3 domain DUF677 PF05055.12 ORX99359.1 - 0.23 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SieB PF14163.6 ORX99359.1 - 8.5 5.9 7.6 1.5 8.3 0.9 2.9 3 0 0 3 3 3 0 Super-infection exclusion protein B AAA_6 PF12774.7 ORX99360.1 - 5.6e-133 443.0 0.7 1.2e-130 435.3 0.0 3.9 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 ORX99360.1 - 1.8e-126 423.0 10.0 1.8e-126 423.0 10.0 4.5 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ORX99360.1 - 8e-119 397.3 9.1 8e-119 397.3 9.1 6.0 6 2 1 7 7 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ORX99360.1 - 4.2e-75 251.6 0.0 4.2e-75 251.6 0.0 5.3 5 1 1 6 6 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORX99360.1 - 7.4e-68 228.7 0.0 3e-67 226.7 0.0 2.2 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 ORX99360.1 - 1.4e-50 172.2 2.1 2.2e-50 171.7 0.4 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 ORX99360.1 - 3e-44 151.5 9.9 6.6e-44 150.3 9.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 ORX99360.1 - 6.6e-43 146.3 0.0 2.5e-36 124.9 0.0 5.3 6 0 0 6 6 6 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORX99360.1 - 2.9e-39 134.5 0.0 7.4e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 ORX99360.1 - 7.9e-32 109.8 0.0 6.1e-30 103.8 0.0 3.6 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 ORX99360.1 - 2e-30 105.6 0.2 4.2e-13 49.5 0.0 7.5 7 1 0 7 7 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 ORX99360.1 - 5e-19 68.7 0.6 1.8e-17 63.7 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 ORX99360.1 - 5.6e-15 55.8 0.3 0.0046 17.2 0.0 6.4 5 0 0 5 5 5 3 AAA domain AAA PF00004.29 ORX99360.1 - 2.9e-13 50.4 0.1 0.0022 18.4 0.0 5.8 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORX99360.1 - 4.2e-10 40.0 3.1 0.04 14.1 0.0 5.2 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 ORX99360.1 - 3.6e-08 34.0 7.5 0.39 11.1 0.1 7.3 6 1 1 7 7 6 1 AAA ATPase domain AAA_18 PF13238.6 ORX99360.1 - 8.9e-08 32.8 1.5 0.055 14.0 0.0 5.5 5 0 0 5 5 4 2 AAA domain Mg_chelatase PF01078.21 ORX99360.1 - 1.1e-06 28.2 0.6 0.16 11.3 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 ORX99360.1 - 4.2e-06 26.9 0.0 5.2e-05 23.4 0.0 3.1 3 0 0 3 3 1 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 ORX99360.1 - 4.7e-06 26.1 0.0 0.18 11.2 0.0 4.4 4 0 0 4 4 4 1 FtsK/SpoIIIE family T2SSE PF00437.20 ORX99360.1 - 1.6e-05 24.1 0.0 0.04 13.0 0.0 3.9 4 0 0 4 4 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 ORX99360.1 - 0.00013 21.6 0.0 0.79 9.5 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORX99360.1 - 0.00018 22.0 0.0 7.6 7.1 0.0 4.7 3 0 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 ORX99360.1 - 0.00055 19.7 0.5 20 4.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain LOH1CR12 PF10158.9 ORX99360.1 - 0.0011 19.0 14.6 0.057 13.5 0.3 5.6 4 0 0 4 4 4 1 Tumour suppressor protein IstB_IS21 PF01695.17 ORX99360.1 - 0.0019 17.9 0.9 0.6 9.8 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 ORX99360.1 - 0.0019 18.5 2.6 0.32 11.3 0.0 4.6 5 0 0 5 5 4 1 AAA domain Rad17 PF03215.15 ORX99360.1 - 0.0026 17.7 0.3 29 4.5 0.0 4.6 5 0 0 5 5 4 0 Rad17 P-loop domain AAA_25 PF13481.6 ORX99360.1 - 0.0028 17.3 0.0 0.32 10.5 0.0 3.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 ORX99360.1 - 0.0069 16.3 2.1 29 4.5 0.0 5.0 4 0 0 4 4 4 0 NACHT domain RNA_helicase PF00910.22 ORX99360.1 - 0.0074 16.7 0.0 13 6.2 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 ORX99360.1 - 0.011 15.4 0.7 52 3.5 0.0 5.1 5 0 0 5 5 4 0 AAA domain Spc7 PF08317.11 ORX99360.1 - 0.51 9.2 36.8 0.01 14.8 13.1 4.6 4 0 0 4 4 4 0 Spc7 kinetochore protein Pkinase PF00069.25 ORX99361.1 - 1e-73 248.0 0.0 1.2e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99361.1 - 7.9e-36 123.7 0.0 1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORX99361.1 - 0.0036 16.3 0.0 0.1 11.5 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORX99361.1 - 0.028 13.7 0.1 0.068 12.5 0.1 1.6 1 1 0 1 1 1 0 Kinase-like COG6 PF06419.11 ORX99362.1 - 1.2e-176 588.7 10.1 1.4e-176 588.5 10.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Exo70 PF03081.15 ORX99362.1 - 1.7e-05 24.1 5.5 1.7e-05 24.1 5.5 2.3 2 2 1 3 3 3 1 Exo70 exocyst complex subunit ING PF12998.7 ORX99362.1 - 0.027 15.0 0.9 0.21 12.2 0.5 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF724 PF05266.14 ORX99362.1 - 0.25 11.1 7.2 24 4.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 ORX99362.1 - 2.2 8.3 5.0 1.2 9.2 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Utp12 PF04003.12 ORX99363.1 - 2.7e-20 72.7 0.9 3.8e-20 72.2 0.9 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 ORX99363.1 - 0.088 12.5 0.1 0.25 11.0 0.1 1.7 1 1 1 2 2 2 0 UTP15 C terminal RRN3 PF05327.11 ORX99363.1 - 0.1 11.1 6.8 0.13 10.8 6.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5320 PF17253.2 ORX99364.1 - 2.4e-05 25.3 15.7 0.11 13.5 0.1 3.7 3 0 0 3 3 3 3 Family of unknown function (DUF5320) SRF-TF PF00319.18 ORX99365.1 - 1.8e-17 62.6 0.1 2.8e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA_12 PF13087.6 ORX99367.1 - 2.1e-59 200.5 0.0 2.6e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 ORX99367.1 - 0.0048 16.3 0.0 0.6 9.4 0.0 2.1 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 ORX99367.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 ORX99368.1 - 5.7e-05 23.0 0.3 6.1e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 ORX99368.1 - 0.01 16.0 0.2 0.016 15.3 0.2 1.5 1 1 0 1 1 1 0 Shikimate kinase Phe_tRNA-synt_N PF02912.18 ORX99368.1 - 0.014 15.3 0.5 0.39 10.7 0.2 2.1 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain TSNAXIP1_N PF15739.5 ORX99368.1 - 0.014 15.8 0.2 0.016 15.6 0.2 1.1 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus 4HB_MCP_1 PF12729.7 ORX99368.1 - 0.043 13.4 0.5 0.049 13.2 0.5 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction RNase_J_C PF17770.1 ORX99368.1 - 0.091 13.8 0.3 0.24 12.5 0.3 1.7 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain Ints3 PF10189.9 ORX99369.1 - 9.7e-81 270.3 0.3 2e-80 269.3 0.0 1.7 2 0 0 2 2 2 1 Integrator complex subunit 3 Radical_SAM PF04055.21 ORX99370.1 - 8.6e-18 65.3 0.0 1.5e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ORX99370.1 - 5e-07 29.9 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 ORX99370.1 - 0.0015 18.8 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain YjcB PF15940.5 ORX99370.1 - 0.097 12.9 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function PBP_GOBP PF01395.22 ORX99370.1 - 0.13 12.5 0.9 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 PBP/GOBP family DUF5598 PF18127.1 ORX99370.1 - 0.14 12.6 0.0 15 6.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) DUF4449 PF14613.6 ORX99371.1 - 1.1e-06 28.8 4.0 1.1e-06 28.8 4.0 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Sigma70_ner PF04546.13 ORX99371.1 - 0.0075 16.2 4.4 0.0075 16.2 4.4 3.4 2 1 0 3 3 3 1 Sigma-70, non-essential region SMBP PF16785.5 ORX99371.1 - 0.053 13.7 0.3 0.053 13.7 0.3 3.2 3 0 0 3 3 3 0 Small metal-binding protein YtxH PF12732.7 ORX99371.1 - 0.098 13.2 10.6 1.5 9.4 1.6 4.5 4 0 0 4 4 4 0 YtxH-like protein QIL1 PF15884.5 ORX99371.1 - 0.19 12.3 2.0 0.98 10.1 0.2 3.2 3 0 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 Phasin PF05597.11 ORX99371.1 - 0.42 10.6 4.5 0.94 9.5 1.5 3.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3837 PF12939.7 ORX99371.1 - 1.1 9.7 6.6 1.2 9.6 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) Com_YlbF PF06133.11 ORX99371.1 - 1.3 9.6 17.3 1.6 9.4 3.5 4.9 4 2 0 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA POX PF07526.11 ORX99371.1 - 4.2 7.9 7.1 1.2 9.7 0.6 3.0 2 1 0 2 2 2 0 Associated with HOX DUF4449 PF14613.6 ORX99372.1 - 6.2e-05 23.2 3.3 6.2e-05 23.2 3.3 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF4449) Speriolin_C PF15059.6 ORX99372.1 - 0.0026 17.9 0.6 0.0092 16.1 0.6 1.9 1 0 0 1 1 1 1 Speriolin C-terminus QIL1 PF15884.5 ORX99372.1 - 0.039 14.5 0.6 0.45 11.2 0.5 3.0 1 1 1 2 2 2 0 MICOS complex subunit MIC13, QIL1 SpoVIF PF14069.6 ORX99372.1 - 0.18 11.6 6.0 0.072 12.9 0.6 3.0 3 0 0 3 3 3 0 Stage VI sporulation protein F HeLo PF14479.6 ORX99372.1 - 0.77 9.6 7.8 0.69 9.7 0.2 3.5 1 1 2 3 3 3 0 Prion-inhibition and propagation YtxH PF12732.7 ORX99372.1 - 0.77 10.3 7.2 18 5.9 0.6 4.3 4 0 0 4 4 4 0 YtxH-like protein Sec7 PF01369.20 ORX99373.1 - 1.1e-33 116.5 0.7 2.1e-33 115.6 0.7 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORX99373.1 - 8.2e-18 64.9 0.0 3.3e-17 62.9 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORX99373.1 - 1.6e-15 57.5 0.0 7e-15 55.4 0.0 2.2 1 0 0 1 1 1 1 PH domain Dfp1_Him1_M PF08630.10 ORX99374.1 - 1.4e-26 93.2 0.0 1.5e-25 89.9 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 ORX99374.1 - 1.5e-19 69.8 0.8 3.2e-19 68.8 0.8 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 ORX99374.1 - 0.029 14.7 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORX99374.1 - 0.03 14.3 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain WES_acyltransf PF03007.16 ORX99374.1 - 0.23 11.2 0.6 0.69 9.6 0.4 1.9 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Cu-oxidase PF00394.22 ORX99375.1 - 4.4e-40 137.4 0.6 1.2e-38 132.7 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORX99375.1 - 9.3e-33 112.8 1.3 9.3e-33 112.8 1.3 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORX99375.1 - 8.7e-28 96.8 11.5 2.6e-27 95.3 1.0 3.5 2 2 0 2 2 2 2 Multicopper oxidase Beach PF02138.18 ORX99376.1 - 2.4e-128 427.3 0.4 3.2e-128 426.9 0.4 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 ORX99376.1 - 1e-14 54.6 8.1 0.00011 22.9 0.2 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99376.1 - 0.0016 18.7 0.1 4 7.8 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 ORX99376.1 - 0.14 11.4 0.2 0.28 10.4 0.2 1.4 1 0 0 1 1 1 0 CPSF A subunit region Mito_carr PF00153.27 ORX99379.1 - 4.7e-53 177.1 2.0 8e-20 70.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_3 PF07859.13 ORX99380.1 - 2.7e-40 138.5 0.0 3.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX99380.1 - 8.6e-18 64.3 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 ORX99380.1 - 2.2e-05 24.2 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORX99380.1 - 0.0029 16.9 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PARP PF00644.20 ORX99380.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Peptidase_S9 PF00326.21 ORX99380.1 - 0.2 11.1 0.0 0.48 9.8 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family TALPID3 PF15324.6 ORX99381.1 - 1.2 6.7 3.5 1.5 6.4 3.5 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Homeodomain PF00046.29 ORX99382.1 - 4.7e-17 61.6 6.6 5.1e-17 61.5 6.6 1.0 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORX99382.1 - 0.0063 16.3 0.1 0.077 12.8 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DUF1778 PF08681.11 ORX99382.1 - 0.0065 16.4 0.2 0.0084 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) YdaS_antitoxin PF15943.5 ORX99382.1 - 0.0099 15.7 0.1 0.029 14.2 0.0 1.7 1 1 1 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 ORX99382.1 - 0.015 15.2 1.0 0.019 14.9 0.7 1.5 1 1 0 1 1 1 0 Homeobox KN domain HTH_28 PF13518.6 ORX99382.1 - 0.036 14.2 0.0 6.4 7.0 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain Imm5 PF14423.6 ORX99383.1 - 0.067 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 Imm5 PF14423.6 ORX99384.1 - 0.07 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 Methyltransf_25 PF13649.6 ORX99386.1 - 2.2e-11 44.3 0.0 3.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORX99386.1 - 3.2e-10 40.5 0.0 4.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX99386.1 - 2e-08 34.9 0.0 3.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX99386.1 - 2.7e-08 33.8 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ORX99386.1 - 8.1e-08 32.1 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 ORX99386.1 - 3.4e-07 29.8 0.0 4.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORX99386.1 - 3.1e-06 27.1 0.0 4.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 ORX99386.1 - 7.3e-06 25.5 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MTS PF05175.14 ORX99386.1 - 9.7e-06 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 ORX99386.1 - 0.08 12.4 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.16 ORX99386.1 - 0.13 10.8 0.0 1.9 6.9 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Sacchrp_dh_NADP PF03435.18 ORX99386.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cupin_1 PF00190.22 ORX99387.1 - 7.4e-44 149.0 0.0 2.1e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ORX99387.1 - 2.2e-26 91.4 1.1 3.7e-13 49.0 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ORX99387.1 - 4.5e-12 46.0 0.6 1e-05 25.5 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 ORX99387.1 - 3e-08 33.8 0.0 0.00025 21.2 0.0 2.4 2 0 0 2 2 2 2 Mif2/CENP-C like MannoseP_isomer PF01050.18 ORX99387.1 - 1.4e-05 25.0 0.0 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_8 PF13621.6 ORX99387.1 - 1.6e-05 24.8 0.0 0.029 14.1 0.0 2.3 2 0 0 2 2 2 2 Cupin-like domain Cupin_3 PF05899.12 ORX99387.1 - 0.00021 20.9 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) ARD PF03079.14 ORX99387.1 - 0.0016 18.6 0.1 0.051 13.8 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family Ectoine_synth PF06339.12 ORX99387.1 - 0.0043 17.2 0.1 1.3 9.2 0.1 2.3 2 0 0 2 2 2 1 Ectoine synthase Cupin_4 PF08007.12 ORX99387.1 - 0.011 15.3 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein FdtA PF05523.11 ORX99387.1 - 0.011 15.4 0.0 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 WxcM-like, C-terminal Cupin_6 PF12852.7 ORX99387.1 - 0.031 14.0 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Cupin GPI PF06560.11 ORX99387.1 - 0.046 13.0 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Acetyltransf_1 PF00583.25 ORX99430.1 - 3.6e-14 53.0 0.0 4.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX99430.1 - 2.1e-08 34.5 0.1 3.7e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORX99430.1 - 4.9e-08 33.0 0.1 7.3e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 ORX99430.1 - 0.0026 16.4 0.1 0.0092 14.6 0.0 1.8 2 0 0 2 2 2 1 Arginine N-succinyltransferase beta subunit Rubredoxin_C PF18267.1 ORX99430.1 - 0.15 12.0 0.2 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain Peptidase_S9 PF00326.21 ORX99431.1 - 6.2e-43 146.7 0.0 9.3e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORX99431.1 - 7.1e-07 29.0 0.0 1.7e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORX99431.1 - 0.00031 20.4 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORX99431.1 - 0.0042 15.8 0.3 0.083 11.6 0.3 2.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 ORX99431.1 - 0.0056 16.2 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase DUF829 PF05705.14 ORX99431.1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_4 PF08386.10 ORX99431.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF2920 PF11144.8 ORX99431.1 - 0.072 12.3 0.1 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Esterase PF00756.20 ORX99431.1 - 0.081 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 ORX99431.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Aminotran_1_2 PF00155.21 ORX99432.1 - 5.3e-52 177.2 0.0 6.2e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORX99432.1 - 0.00037 19.9 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORX99432.1 - 0.0028 16.5 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 ORX99432.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Bclx_interact PF08945.10 ORX99432.1 - 2.9 7.7 4.4 14 5.5 0.3 3.1 3 0 0 3 3 3 0 Bcl-x interacting, BH3 domain Mito_carr PF00153.27 ORX99433.1 - 3.5e-65 216.0 0.5 3.7e-20 71.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.12 ORX99434.1 - 2.6e-126 409.2 56.0 1.5e-10 41.4 0.0 14.4 15 0 0 15 15 15 14 Sel1 repeat Flu_M1_C PF08289.11 ORX99434.1 - 0.026 14.7 0.0 21 5.4 0.0 4.5 3 2 1 5 5 5 0 Influenza Matrix protein (M1) C-terminal domain Neuromodulin_N PF10580.9 ORX99434.1 - 0.12 12.2 0.2 9.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Gap junction protein N-terminal region Astro_capsid_p2 PF16580.5 ORX99434.1 - 0.2 11.0 0.7 25 4.2 0.0 3.6 3 1 1 4 4 4 0 C-terminal tail of astrovirus capsid projection or spike pP_pnuc_1 PF18165.1 ORX99434.1 - 0.82 9.6 2.4 2.8e+02 1.4 0.0 4.8 4 2 1 5 5 5 0 Predicted pPIWI-associating nuclease Pericardin_rpt PF07054.11 ORX99434.1 - 2.6 8.2 7.0 82 3.4 0.1 4.7 5 0 0 5 5 5 0 Pericardin like repeat Mob1_phocein PF03637.17 ORX99435.1 - 2e-68 229.7 0.4 2.3e-68 229.5 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pyr_redox_2 PF07992.14 ORX99436.1 - 1.7e-19 70.1 0.0 6.1e-12 45.4 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORX99436.1 - 0.0004 20.9 1.4 0.1 13.2 0.2 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX99436.1 - 0.0019 17.8 1.9 1.6 8.3 0.2 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORX99436.1 - 0.0028 17.0 0.0 1.2 8.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORX99436.1 - 0.0037 17.3 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORX99436.1 - 0.0065 15.6 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORX99436.1 - 0.013 14.6 0.1 0.23 10.5 0.1 2.1 1 1 1 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORX99436.1 - 0.034 13.4 0.7 0.087 12.1 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 ORX99436.1 - 0.066 12.0 0.1 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 ORX99436.1 - 0.072 13.3 0.2 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORX99436.1 - 0.1 11.3 0.9 3 6.4 0.2 2.5 2 1 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ORX99436.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family CAP PF00188.26 ORX99439.1 - 1.1e-14 55.3 0.2 1.6e-14 54.8 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_S8 PF00082.22 ORX99440.1 - 1e-31 110.4 15.1 2.3e-31 109.2 15.1 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORX99440.1 - 0.00012 22.6 0.0 0.00025 21.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lipase_3 PF01764.25 ORX99441.1 - 2.6e-31 108.4 0.0 3.9e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORX99441.1 - 0.005 17.5 0.0 0.006 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORX99441.1 - 0.079 12.5 0.2 10 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) MRC1 PF09444.10 ORX99442.1 - 0.071 13.6 1.8 0.13 12.7 0.3 2.0 2 0 0 2 2 2 0 MRC1-like domain PLA2G12 PF06951.11 ORX99444.1 - 4.5e-13 49.5 13.2 5.8e-13 49.1 13.2 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 ORX99444.1 - 0.0007 20.2 8.3 0.0007 20.2 8.3 1.9 2 1 0 2 2 2 1 Prokaryotic phospholipase A2 Ctr PF04145.15 ORX99445.1 - 3.3e-27 95.9 11.6 1.2e-26 94.1 11.6 1.7 1 1 0 1 1 1 1 Ctr copper transporter family zf-C3HC4_2 PF13923.6 ORX99446.1 - 1.1e-10 41.2 11.2 2.1e-10 40.2 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 ORX99446.1 - 2.5e-08 33.4 0.0 5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.6 ORX99446.1 - 9.9e-07 28.7 7.4 3e-06 27.2 5.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORX99446.1 - 1.1e-06 28.4 8.8 2.1e-06 27.5 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORX99446.1 - 1.3e-06 28.2 9.8 3.6e-06 26.7 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORX99446.1 - 4.9e-06 26.3 2.1 9.7e-06 25.4 2.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 ORX99446.1 - 1.6e-05 24.7 10.6 3.5e-05 23.7 10.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORX99446.1 - 2.9e-05 24.3 11.3 6.4e-05 23.2 11.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 ORX99446.1 - 6e-05 23.1 6.5 0.00013 22.0 6.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ORX99446.1 - 7.8e-05 22.8 11.4 0.0002 21.5 11.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORX99446.1 - 0.0046 17.0 2.2 0.0094 16.0 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORX99446.1 - 0.0048 17.2 9.7 0.018 15.3 9.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain U-box PF04564.15 ORX99446.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 1 0 U-box domain zf-RING_4 PF14570.6 ORX99446.1 - 0.036 13.9 10.2 0.33 10.8 10.3 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 ORX99446.1 - 0.045 13.6 7.0 0.57 10.1 3.7 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LEM PF03020.15 ORX99446.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 LEM domain Ish1 PF10281.9 ORX99446.1 - 0.054 13.8 0.4 2.6 8.4 0.3 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein zinc-ribbons_6 PF07191.12 ORX99446.1 - 0.072 13.1 6.0 0.23 11.4 6.0 1.8 1 1 0 1 1 1 0 zinc-ribbons Prok-RING_4 PF14447.6 ORX99446.1 - 0.14 12.0 11.6 4.4 7.2 12.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 ORX99446.1 - 0.37 11.3 6.8 31 5.1 0.8 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 ORX99446.1 - 1.8 9.0 9.8 2.2 8.7 7.4 2.4 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 ORX99446.1 - 2.9 7.8 7.3 8.5 6.3 6.8 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit HAD_2 PF13419.6 ORX99447.1 - 1.7e-17 64.0 0.1 5.9e-16 59.0 0.1 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORX99447.1 - 6.7e-15 56.0 0.0 8e-12 45.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORX99447.1 - 2.8e-09 36.9 0.0 6.1e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORX99447.1 - 0.00068 20.1 0.0 0.0096 16.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORX99447.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Sulfotransfer_4 PF17784.1 ORX99447.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain Hydrolase_3 PF08282.12 ORX99447.1 - 0.2 11.4 0.1 17 5.0 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase HD PF01966.22 ORX99448.1 - 1.1e-13 51.5 1.1 2.8e-13 50.1 0.2 2.1 2 1 1 3 3 3 1 HD domain PDEase_I PF00233.19 ORX99448.1 - 0.0019 18.0 0.1 0.0085 15.8 0.0 2.2 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HMG_box PF00505.19 ORX99449.1 - 3.9e-21 75.2 2.8 4.3e-21 75.1 2.8 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX99449.1 - 1.8e-08 34.8 1.8 1.9e-08 34.7 1.8 1.0 1 0 0 1 1 1 1 HMG-box domain Cyclin PF08613.11 ORX99450.1 - 1.6e-33 116.3 0.6 1.9e-33 116.1 0.6 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORX99450.1 - 1.6e-09 37.6 0.2 1.9e-09 37.4 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_M20 PF01546.28 ORX99451.1 - 1.1e-18 67.8 0.2 2.6e-18 66.5 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORX99451.1 - 1.2e-17 63.7 0.4 1e-16 60.8 0.2 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORX99451.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 SAT PF16073.5 ORX99451.1 - 0.061 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_M20 PF01546.28 ORX99452.1 - 6.5e-21 75.0 0.1 3.7e-20 72.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORX99452.1 - 2.5e-17 62.8 0.3 2.1e-16 59.8 0.1 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORX99452.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.28 ORX99453.1 - 7.6e-20 71.5 0.1 4.3e-19 69.0 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORX99453.1 - 4.4e-17 62.0 0.2 3.8e-16 59.0 0.1 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORX99453.1 - 0.0059 16.3 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Ribosomal_S19e PF01090.19 ORX99454.1 - 2.8e-59 198.7 0.4 3.1e-59 198.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_CodY PF08222.11 ORX99454.1 - 0.14 11.8 0.0 19 4.9 0.0 2.3 2 0 0 2 2 2 0 CodY helix-turn-helix domain HLH PF00010.26 ORX99455.1 - 3.4e-16 58.9 2.7 6.1e-16 58.1 2.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HrpA_pilin PF09589.10 ORX99455.1 - 0.078 13.7 0.1 0.14 12.9 0.1 1.4 1 0 0 1 1 1 0 HrpA pilus formation protein UPF0242 PF06785.11 ORX99455.1 - 0.11 12.6 5.8 0.12 12.4 5.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EphA2_TM PF14575.6 ORX99456.1 - 0.27 12.2 1.6 19 6.2 0.1 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 ORX99456.1 - 1.2 9.4 4.1 5.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Presenilin PF01080.17 ORX99456.1 - 1.6 7.4 11.1 2 7.1 6.3 2.1 2 0 0 2 2 2 0 Presenilin zf-rbx1 PF12678.7 ORX99457.1 - 1.2e-09 38.3 6.0 7.3e-09 35.8 4.6 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORX99457.1 - 5.8e-08 32.5 0.0 2.1e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX99457.1 - 6.1e-08 32.9 0.8 6.1e-08 32.9 0.8 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 ORX99457.1 - 1.8e-07 31.1 2.0 1.7e-06 27.9 2.0 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORX99457.1 - 6.9e-06 25.8 1.0 6.9e-06 25.8 1.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORX99457.1 - 2.7e-05 23.7 2.3 0.00042 19.9 0.3 2.8 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORX99457.1 - 0.00039 20.1 0.4 0.00039 20.1 0.4 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 ORX99457.1 - 0.001 19.0 1.0 0.018 15.0 0.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORX99457.1 - 0.0078 16.4 0.2 0.0078 16.4 0.2 2.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORX99457.1 - 0.019 15.0 1.8 0.067 13.2 0.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORX99457.1 - 0.02 14.8 5.3 0.45 10.4 0.5 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORX99457.1 - 0.051 13.8 0.2 0.18 12.0 0.2 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORX99457.1 - 0.074 12.9 2.5 0.15 11.9 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Pan3_PK PF18101.1 ORX99458.1 - 5.2e-63 211.1 0.1 9.6e-63 210.3 0.1 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 ORX99458.1 - 5.6e-08 32.5 0.0 9.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Chromo PF00385.24 ORX99459.1 - 0.069 13.1 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 ORX99460.1 - 2.4e-20 72.7 0.0 4.7e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX99460.1 - 1.7e-06 28.0 4.4 8.2e-05 22.6 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 ORX99460.1 - 2.1e-05 24.1 0.2 0.00053 19.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORX99460.1 - 4.2e-05 23.7 0.0 0.0054 16.8 0.4 2.5 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 ORX99460.1 - 7.2e-05 22.4 0.1 0.014 15.0 0.1 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 ORX99460.1 - 0.019 15.2 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORX99460.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORX99460.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zip PF02535.22 ORX99461.1 - 0.35 10.0 1.8 0.38 9.9 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ATF7IP_BD PF16788.5 ORX99461.1 - 1.3 9.1 12.6 1.9 8.5 12.6 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain Menin PF05053.13 ORX99461.1 - 2.3 6.5 4.5 2.6 6.3 4.5 1.1 1 0 0 1 1 1 0 Menin CorA PF01544.18 ORX99463.1 - 3.7e-45 154.5 0.9 3.7e-45 154.5 0.9 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein BBP1_N PF15271.6 ORX99463.1 - 0.046 14.5 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DUF997 PF06196.12 ORX99463.1 - 0.12 12.4 2.6 0.23 11.5 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF997) NDK PF00334.19 ORX99464.1 - 1.4e-171 562.5 0.1 2.4e-44 150.6 0.0 4.0 4 0 0 4 4 4 4 Nucleoside diphosphate kinase Flu_M1 PF00598.19 ORX99464.1 - 0.038 13.5 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Influenza Matrix protein (M1) CYLD_phos_site PF16607.5 ORX99464.1 - 0.084 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured Lactamase_B_4 PF13691.6 ORX99465.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease SPA PF08616.10 ORX99466.1 - 1.2e-12 47.8 0.2 8.3e-12 45.1 0.0 2.4 3 0 0 3 3 3 1 Stabilization of polarity axis Avl9 PF09794.9 ORX99466.1 - 0.0026 16.5 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 ORX99466.1 - 0.0046 16.9 0.1 0.045 13.7 0.1 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain Proteasom_Rpn13 PF04683.13 ORX99467.1 - 1.1e-30 106.0 0.1 1.4e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF5595 PF18077.1 ORX99467.1 - 0.027 14.5 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Bud13 PF09736.9 ORX99468.1 - 2.8e-51 173.7 7.3 2.8e-51 173.7 7.3 2.6 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex FmdE PF02663.14 ORX99468.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF4407 PF14362.6 ORX99468.1 - 0.056 12.8 1.5 0.077 12.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 ORX99469.1 - 9.9e-204 678.1 0.0 1.1e-203 677.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 ORX99469.1 - 0.046 13.3 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus PPR_2 PF13041.6 ORX99470.1 - 1.1e-101 332.9 24.0 3.5e-19 68.7 0.3 7.1 1 1 6 7 7 7 7 PPR repeat family PPR_1 PF12854.7 ORX99470.1 - 3.1e-68 225.1 1.8 2.8e-10 39.7 0.0 8.1 8 0 0 8 8 8 8 PPR repeat PPR PF01535.20 ORX99470.1 - 4.1e-63 205.3 1.6 5.7e-08 32.5 0.2 7.4 7 0 0 7 7 7 7 PPR repeat PPR_3 PF13812.6 ORX99470.1 - 1.9e-49 165.6 13.2 5.4e-13 48.8 0.1 5.1 2 2 2 5 5 5 5 Pentatricopeptide repeat domain PPR_long PF17177.4 ORX99470.1 - 2.6e-25 89.1 0.2 1.3e-08 34.5 0.0 3.2 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORX99470.1 - 5.4e-07 30.0 9.9 0.3 11.5 0.5 5.2 2 2 3 5 5 5 4 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ORX99470.1 - 2.8e-06 27.2 3.2 3.4 7.6 0.0 5.6 1 1 4 6 6 6 1 Mitochondrial ATPase expression MRP-S27 PF10037.9 ORX99470.1 - 4.1e-06 25.9 0.5 0.05 12.5 0.0 4.0 1 1 2 4 4 4 2 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 ORX99470.1 - 3e-05 24.5 0.0 2.7 9.0 0.0 4.8 3 2 3 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 ORX99470.1 - 5.2e-05 23.0 0.3 2.1 8.0 0.0 4.2 2 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 ORX99470.1 - 0.00033 21.1 0.0 0.35 11.4 0.1 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat AEP1 PF17049.5 ORX99470.1 - 0.00039 19.6 5.8 0.2 10.7 0.1 3.6 1 1 3 4 4 4 2 ATPase expression protein 1 LisH_2 PF16045.5 ORX99470.1 - 0.062 12.3 0.3 7.1 5.7 0.0 3.4 3 0 0 3 3 3 0 LisH Fer4_12 PF13353.6 ORX99470.1 - 0.099 12.9 0.4 19 5.5 0.1 3.7 1 1 3 5 5 5 0 4Fe-4S single cluster domain Nterm_IS4 PF13006.7 ORX99470.1 - 0.11 12.7 0.0 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal Prp18 PF02840.15 ORX99470.1 - 0.57 10.2 5.7 5.7 7.0 0.2 3.3 4 0 0 4 4 4 0 Prp18 domain Clathrin PF00637.20 ORX99470.1 - 4.7 7.1 6.9 8.5 6.2 0.3 3.1 2 2 0 3 3 3 0 Region in Clathrin and VPS SNF2_N PF00176.23 ORX99471.1 - 1.1e-45 155.9 9.2 5.7e-45 153.6 3.4 3.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 ORX99471.1 - 9.7e-10 38.2 8.3 2.5e-09 36.9 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORX99471.1 - 1.9e-07 31.3 11.6 5.5e-07 29.8 11.6 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORX99471.1 - 3e-07 30.2 9.7 7.2e-07 29.0 9.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORX99471.1 - 3.2e-07 30.1 12.2 7.3e-07 28.9 12.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 ORX99471.1 - 7.9e-07 29.4 0.2 7.9e-07 29.4 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 ORX99471.1 - 3.6e-05 23.5 12.1 7.9e-05 22.5 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORX99471.1 - 9.6e-05 22.3 8.2 0.00022 21.2 8.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORX99471.1 - 9.8e-05 22.2 10.6 0.00028 20.8 10.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORX99471.1 - 0.00017 21.8 10.4 0.00057 20.1 10.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 ORX99471.1 - 0.038 13.6 8.9 0.093 12.4 8.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FleQ PF06490.11 ORX99471.1 - 0.078 13.4 0.4 0.62 10.5 0.1 2.6 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ TPR_16 PF13432.6 ORX99471.1 - 0.1 13.3 1.5 0.97 10.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX99471.1 - 0.11 12.6 1.4 0.49 10.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 ORX99471.1 - 0.13 12.4 9.9 0.3 11.3 9.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.21 ORX99471.1 - 0.27 11.5 6.5 0.78 10.0 6.5 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Bcr-Abl_Oligo PF09036.10 ORX99471.1 - 0.27 11.2 2.6 0.35 10.9 0.3 2.4 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain TPR_8 PF13181.6 ORX99471.1 - 0.59 10.5 3.6 10 6.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Thaumatin PF00314.17 ORX99472.1 - 1.2e-71 240.8 12.5 1.4e-71 240.5 12.5 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORX99472.1 - 0.2 10.9 3.7 0.51 9.6 0.0 2.5 1 1 2 3 3 3 0 Beta-1,3-glucanase Catalase PF00199.19 ORX99473.1 - 4.7e-10 39.1 0.0 1.3e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Catalase SLAC1 PF03595.17 ORX99474.1 - 7.2e-71 239.1 48.4 8.1e-71 238.9 48.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3343 PF11823.8 ORX99474.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) ERCC3_RAD25_C PF16203.5 ORX99508.1 - 1.7e-125 417.2 0.9 3.1e-125 416.3 0.9 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ORX99508.1 - 4.1e-39 133.6 0.3 2.6e-38 131.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX99508.1 - 1.2e-16 61.2 0.0 5.1e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORX99508.1 - 2.8e-12 47.0 0.4 1e-11 45.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ORX99508.1 - 6.1e-10 38.3 0.0 8.1e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 ORX99508.1 - 2.5e-05 24.1 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 ORX99508.1 - 0.0029 17.0 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2075 PF09848.9 ORX99508.1 - 0.054 12.7 0.1 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.25 ORX99509.1 - 4.3e-79 265.6 0.0 5.5e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99509.1 - 3.8e-37 128.0 0.0 5.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORX99509.1 - 6.6e-08 32.8 0.3 3.1e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 ORX99509.1 - 3.9e-07 29.7 0.0 2.7e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORX99509.1 - 0.00031 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORX99509.1 - 0.00049 19.0 0.0 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 ORX99509.1 - 0.001 19.4 0.1 0.028 14.7 0.0 2.9 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 ORX99509.1 - 0.0017 17.4 0.2 0.0049 15.9 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORX99509.1 - 0.056 13.4 0.0 0.23 11.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.17 ORX99510.1 - 1e-32 112.6 1.0 1.9e-32 111.7 1.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding CENP-F_leu_zip PF10473.9 ORX99510.1 - 0.0013 18.8 0.6 0.002 18.2 0.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 ORX99510.1 - 0.025 14.8 0.6 0.043 14.0 0.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) P4Ha_N PF08336.11 ORX99510.1 - 0.036 14.1 0.5 0.082 12.9 0.5 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ntox14 PF15522.6 ORX99510.1 - 0.036 13.5 0.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Novel toxin 14 SHE3 PF17078.5 ORX99510.1 - 0.038 13.7 1.7 0.059 13.1 1.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CorA PF01544.18 ORX99510.1 - 0.063 12.6 1.3 0.089 12.1 1.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 ORX99510.1 - 0.084 13.4 0.1 0.12 12.9 0.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CLZ PF16526.5 ORX99510.1 - 0.11 12.9 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NYAP_C PF15452.6 ORX99512.1 - 0.091 12.6 1.2 0.12 12.2 1.2 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Fungal_trans PF04082.18 ORX99514.1 - 1.8e-33 115.7 0.0 2.8e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORX99514.1 - 1.1e-11 44.7 12.1 2.1e-11 43.8 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain THEG4 PF15834.5 ORX99514.1 - 0.22 11.5 1.3 0.42 10.6 1.3 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 Rep_fac-A_C PF08646.10 ORX99514.1 - 3.7 7.3 4.9 8 6.2 4.9 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain Ski_Sno PF02437.17 ORX99515.1 - 0.086 12.6 0.3 2 8.2 0.2 2.2 1 1 1 2 2 2 0 SKI/SNO/DAC family MRP-L28 PF09812.9 ORX99518.1 - 2.6e-11 43.9 3.4 3.4e-11 43.5 3.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Pneumo_phosprot PF02478.16 ORX99518.1 - 0.0071 15.9 0.2 0.0083 15.7 0.2 1.1 1 0 0 1 1 1 1 Pneumovirus phosphoprotein Adaptin_N PF01602.20 ORX99519.1 - 2.6e-131 438.8 8.0 3.4e-131 438.4 8.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 ORX99519.1 - 1.1e-36 125.4 0.0 4.9e-36 123.3 0.0 2.1 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 ORX99519.1 - 5.3e-15 55.7 0.0 1.4e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.22 ORX99519.1 - 0.013 15.7 0.5 0.43 11.0 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat RTP1_C1 PF10363.9 ORX99519.1 - 0.018 15.2 0.7 0.086 13.0 0.7 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Complex1_LYR_1 PF13232.6 ORX99519.1 - 0.027 15.1 0.2 2.8 8.6 0.0 3.1 3 0 0 3 3 3 0 Complex1_LYR-like Peptidase_M9_N PF08453.10 ORX99519.1 - 0.097 12.4 0.6 0.32 10.7 0.1 2.1 2 0 0 2 2 2 0 Peptidase family M9 N-terminal RasGEF_N_2 PF14663.6 ORX99519.1 - 0.15 12.5 2.3 6.6 7.2 0.1 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GNAT_acetyltr_2 PF13718.6 ORX99520.1 - 2e-98 328.4 0.0 4.6e-98 327.1 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 ORX99520.1 - 3.2e-91 305.2 3.2 5.1e-91 304.6 3.2 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 ORX99520.1 - 3.4e-65 219.2 0.0 1.1e-64 217.6 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 ORX99520.1 - 3.4e-34 116.6 0.3 9.5e-34 115.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 ORX99520.1 - 0.0021 17.8 0.1 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORX99520.1 - 0.0042 17.3 0.0 0.1 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 ORX99520.1 - 0.027 14.2 0.1 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Acetyltransf_1 PF00583.25 ORX99520.1 - 0.028 14.6 0.0 0.083 13.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORX99520.1 - 0.16 12.4 0.0 0.58 10.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Troponin PF00992.20 ORX99520.1 - 0.84 9.9 4.4 31 4.8 0.0 2.5 2 0 0 2 2 2 0 Troponin zf-AN1 PF01428.16 ORX99521.1 - 1.6e-07 31.4 8.4 1.6e-07 31.4 8.4 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger UCR_UQCRX_QCR9 PF05365.12 ORX99522.1 - 7.7e-24 83.4 3.2 9.2e-24 83.2 3.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like EPL1 PF10513.9 ORX99523.1 - 3e-25 89.4 0.3 3e-25 89.4 0.3 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like Sec63 PF02889.16 ORX99525.1 - 2.4e-30 105.5 0.0 4.1e-29 101.5 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 ORX99525.1 - 4.2e-21 74.8 0.9 4.2e-21 74.8 0.9 2.4 3 0 0 3 3 3 1 DnaJ domain STN1_2 PF09170.10 ORX99525.1 - 0.073 13.3 0.4 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Y_phosphatase PF00102.27 ORX99526.1 - 2.4e-75 253.2 0.1 3.2e-75 252.7 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORX99526.1 - 3.6e-10 40.3 0.0 9.1e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 ORX99526.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3385 PF11865.8 ORX99526.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) RRM_1 PF00076.22 ORX99527.1 - 7.8e-25 86.5 0.9 1.7e-16 59.7 0.0 3.6 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 ORX99527.1 - 0.00023 21.1 1.0 0.038 14.0 0.1 2.5 1 1 1 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORX99527.1 - 0.00052 20.1 0.1 0.15 12.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 ORX99527.1 - 0.0058 16.6 0.1 1.9 8.6 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CPSF100_C PF13299.6 ORX99527.1 - 0.0078 16.4 1.2 0.0078 16.4 1.2 2.6 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 ORX99528.1 - 2.5e-31 109.1 2.4 1.1e-22 80.8 0.8 6.3 2 2 1 3 3 3 2 Spt20 family TauD PF02668.16 ORX99529.1 - 2.2e-58 198.2 0.1 2.7e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 ORX99530.1 - 2.2e-58 198.2 0.1 2.7e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 ORX99531.1 - 7.9e-95 318.4 28.2 9.1e-95 318.1 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORX99531.1 - 2.7e-24 85.8 24.7 2.7e-24 85.8 24.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3472 PF11958.8 ORX99532.1 - 0.00013 22.4 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Ntox6 PF15544.6 ORX99532.1 - 0.1 12.2 0.3 2.1 7.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial toxin 6 DUF3472 PF11958.8 ORX99533.1 - 9.5e-08 32.7 1.1 1.6e-07 31.9 1.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORX99533.1 - 1.8e-05 24.7 0.3 2.8e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF5561 PF17716.1 ORX99567.1 - 0.022 14.1 1.0 0.033 13.5 0.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5561) Zip PF02535.22 ORX99567.1 - 0.26 10.5 11.7 0.44 9.7 11.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 ORX99567.1 - 0.79 7.8 15.4 0.91 7.6 15.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.13 ORX99567.1 - 0.98 9.1 19.5 1.1 8.9 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOG2 PF10428.9 ORX99567.1 - 1.1 8.4 20.2 1.4 8.1 20.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 ORX99567.1 - 2.4 6.9 12.4 2.8 6.6 12.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 ORX99567.1 - 3.1 6.0 15.2 3.9 5.6 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Mucin PF01456.17 ORX99567.1 - 3.2 7.7 19.4 5.5 7.0 19.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ALMT PF11744.8 ORX99567.1 - 4.7 5.9 7.7 6.1 5.6 7.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter MGC-24 PF05283.11 ORX99567.1 - 5 7.6 24.6 5.7 7.4 9.9 2.4 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mitofilin PF09731.9 ORX99567.1 - 6.3 5.5 15.6 7.3 5.3 15.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ABC2_membrane PF01061.24 ORX99568.1 - 3.5e-34 118.1 22.1 3.5e-34 118.1 22.1 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 ORX99568.1 - 3.8e-27 95.5 0.0 7.9e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORX99568.1 - 0.00036 20.4 0.1 0.38 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 ORX99568.1 - 0.00089 19.0 0.1 0.12 12.0 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORX99568.1 - 0.0032 17.4 0.1 0.0064 16.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORX99568.1 - 0.0081 15.9 0.4 0.022 14.5 0.4 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ORX99568.1 - 0.017 14.6 0.1 0.37 10.2 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORX99568.1 - 0.027 14.7 0.1 0.064 13.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ORX99568.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 ORX99568.1 - 0.069 13.5 0.2 0.15 12.5 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ORX99568.1 - 0.099 12.4 0.4 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORX99568.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORX99568.1 - 0.22 12.1 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORX99568.1 - 0.34 10.6 0.7 0.62 9.8 0.7 1.3 1 0 0 1 1 1 0 AAA domain DUF4051 PF13260.6 ORX99568.1 - 0.99 9.2 5.5 2.1 8.2 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Laminin_EGF PF00053.24 ORX99568.1 - 1.7 8.9 23.4 0.039 14.1 4.9 3.5 2 1 1 3 3 3 0 Laminin EGF domain ABC2_membrane_3 PF12698.7 ORX99568.1 - 3.7 6.6 40.7 0.012 14.8 29.8 2.2 2 1 1 3 3 3 0 ABC-2 family transporter protein PDR_CDR PF06422.12 ORX99568.1 - 3.9 7.5 5.4 0.63 10.0 0.3 2.4 2 0 0 2 2 2 0 CDR ABC transporter Pribosyl_synth PF14572.6 ORX99570.1 - 2.2e-48 164.8 4.5 4.1e-40 137.8 1.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORX99570.1 - 4.8e-48 161.9 0.7 3.3e-47 159.2 0.1 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORX99570.1 - 8.6e-16 57.9 3.8 2.7e-14 53.0 1.2 2.5 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Glyco_transf_21 PF13506.6 ORX99571.1 - 5.8e-42 143.1 0.0 8.8e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORX99571.1 - 9.4e-22 78.0 0.0 1.4e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX99571.1 - 5.9e-13 49.2 1.6 5.9e-13 49.2 1.6 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX99571.1 - 1.6e-05 24.8 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 GPP34 PF05719.11 ORX99572.1 - 1e-39 136.7 0.0 1.1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Exo_endo_phos PF03372.23 ORX99573.1 - 4.1e-12 46.1 0.0 8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 ORX99573.1 - 6.2e-06 26.9 8.8 0.0033 18.2 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 ORX99573.1 - 0.0071 15.0 4.4 0.79 8.3 0.1 3.7 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Cas_Csn2 PF09711.10 ORX99573.1 - 0.047 13.4 0.3 0.089 12.4 0.3 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) Tli4_C PF18426.1 ORX99573.1 - 0.08 13.3 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain DUF5039 PF16442.5 ORX99573.1 - 0.19 11.3 2.2 0.14 11.7 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) Med26_C PF15693.5 ORX99574.1 - 0.17 12.0 0.5 0.29 11.3 0.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal GMP_synt_C PF00958.22 ORX99576.1 - 1.3e-46 156.6 0.1 2.8e-46 155.5 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ORX99576.1 - 3.1e-35 121.7 0.0 5.8e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORX99576.1 - 1.9e-09 37.6 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 ORX99576.1 - 2.4e-08 33.4 0.1 1.5e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 ORX99576.1 - 0.0023 16.8 0.1 0.0064 15.3 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 ORX99576.1 - 0.004 16.7 0.0 0.035 13.6 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 ORX99576.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 ORX99576.1 - 0.085 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) MMR_HSR1_Xtn PF16897.5 ORX99577.1 - 9.2e-44 147.8 0.1 1.9e-43 146.8 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORX99577.1 - 2.2e-23 82.1 0.1 4.3e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 ORX99577.1 - 2.8e-21 75.7 0.0 6.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORX99577.1 - 4.8e-12 45.7 0.1 2.5e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 ORX99577.1 - 0.00031 19.8 0.7 0.0031 16.5 0.3 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ORX99577.1 - 0.0021 17.6 0.4 4 6.9 0.0 3.8 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORX99577.1 - 0.0045 17.1 0.2 1.6 8.7 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Arf PF00025.21 ORX99577.1 - 0.091 12.2 0.1 0.42 10.0 0.1 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family ORC6 PF05460.13 ORX99578.1 - 3.2e-17 62.8 3.8 4.3e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) MID_MedPIWI PF18296.1 ORX99578.1 - 0.0046 16.8 1.6 0.0075 16.1 1.6 1.3 1 0 0 1 1 1 1 MID domain of medPIWI DUF1631 PF07793.11 ORX99578.1 - 0.034 12.6 0.2 0.045 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SRP-alpha_N PF04086.13 ORX99578.1 - 0.035 14.0 0.8 0.056 13.4 0.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RCSD PF05177.12 ORX99578.1 - 0.12 13.3 13.5 0.18 12.7 13.5 1.2 1 0 0 1 1 1 0 RCSD region zf-Tim10_DDP PF02953.15 ORX99579.1 - 2.5e-21 75.1 3.8 2.9e-21 74.9 3.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORX99579.1 - 0.014 15.1 2.2 0.18 11.5 2.0 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) IpaB_EvcA PF03278.13 ORX99579.1 - 0.016 14.9 0.3 0.38 10.4 0.1 2.0 1 1 1 2 2 2 0 IpaB/EvcA family Tam41_Mmp37 PF09139.11 ORX99579.1 - 0.04 13.4 0.1 0.04 13.4 0.1 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Phasin_2 PF09361.10 ORX99579.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.7 1 1 1 2 2 2 0 Phasin protein Chromo PF00385.24 ORX99579.1 - 0.33 10.9 2.4 6.5 6.7 0.1 2.9 2 1 1 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Rpr2 PF04032.16 ORX99580.1 - 2.5e-17 62.9 6.2 1.1e-16 60.9 6.2 2.1 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4674 PF15719.5 ORX99580.1 - 1e-06 29.0 20.5 1.4e-06 28.5 20.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) RNA_POL_M_15KD PF02150.16 ORX99580.1 - 0.021 14.7 2.7 0.13 12.2 0.3 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit RHINO PF15319.6 ORX99580.1 - 0.075 13.1 11.0 0.1 12.6 11.0 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein NOB1_Zn_bind PF08772.11 ORX99580.1 - 0.27 11.4 8.3 0.094 12.9 1.6 2.6 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Formyl_trans_N PF00551.19 ORX99581.1 - 6.4e-28 97.7 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ORX99581.1 - 6e-18 64.9 0.0 1.2e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain RPAP2_Rtr1 PF04181.13 ORX99582.1 - 6.9e-19 68.0 0.9 1.6e-18 66.8 0.9 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family FGF-BP1 PF06473.12 ORX99582.1 - 4.8 7.0 8.3 2.9 7.6 3.5 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Microtub_bind PF13931.6 ORX99582.1 - 8.3 6.8 12.1 0.52 10.7 2.0 2.6 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding RNase_T PF00929.24 ORX99583.1 - 0.0032 18.0 0.0 0.0067 17.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORX99583.1 - 0.03 14.0 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 3'-5' exonuclease Prefoldin_2 PF01920.20 ORX99584.1 - 0.0011 18.9 5.6 0.0028 17.6 5.6 1.6 1 1 0 1 1 1 1 Prefoldin subunit TolA_bind_tri PF16331.5 ORX99584.1 - 0.011 15.8 4.5 0.12 12.5 0.2 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation CEP209_CC5 PF16574.5 ORX99584.1 - 0.086 13.0 5.7 0.092 12.9 5.7 1.0 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 ABC_tran_CTD PF16326.5 ORX99584.1 - 0.27 11.5 6.9 2.6 8.4 1.9 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 ORX99584.1 - 0.37 10.6 5.5 0.26 11.1 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 ORX99584.1 - 0.77 10.2 10.4 2.3 8.6 5.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.6 ORX99584.1 - 0.78 9.8 9.4 0.2 11.7 4.7 1.9 1 1 1 2 2 2 0 FlxA-like protein Ribosomal_L6 PF00347.23 ORX99585.1 - 2.1e-31 108.4 4.4 4.2e-17 62.6 1.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Exotox-A_cataly PF09009.10 ORX99585.1 - 0.13 12.0 0.1 0.72 9.6 0.1 2.2 2 1 0 2 2 2 0 Exotoxin A catalytic Cyclin PF08613.11 ORX99586.1 - 1.5e-07 32.0 0.1 6.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORX99586.1 - 2.9e-07 30.3 0.0 5.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Velvet PF11754.8 ORX99587.1 - 1.5e-48 166.0 0.7 1.1e-29 104.1 0.3 2.0 1 1 1 2 2 2 2 Velvet factor DUF1376 PF07120.11 ORX99587.1 - 0.035 14.4 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) LIM_bind PF01803.16 ORX99588.1 - 8.3e-59 199.0 6.5 1.4e-58 198.3 0.0 2.6 2 0 0 2 2 2 1 LIM-domain binding protein Septin PF00735.18 ORX99589.1 - 1.6e-117 391.8 0.1 1.6e-117 391.8 0.1 2.0 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORX99589.1 - 3.7e-07 30.2 0.5 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX99589.1 - 1.9e-05 24.7 0.2 1.9e-05 24.7 0.2 3.1 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 ORX99589.1 - 3.5e-05 23.4 5.1 0.0009 18.8 0.0 3.2 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORX99589.1 - 0.00061 19.9 5.1 0.23 11.5 0.1 3.5 3 0 0 3 3 3 2 Dynamin family Ras PF00071.22 ORX99589.1 - 0.0053 16.4 0.2 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.18 ORX99589.1 - 0.006 16.0 1.8 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_tran PF00005.27 ORX99589.1 - 0.0067 16.9 4.9 0.037 14.5 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 ORX99589.1 - 0.0076 15.6 1.4 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 ORX99589.1 - 0.02 15.1 0.5 0.039 14.2 0.0 1.8 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORX99589.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myb_DNA-bind_3 PF12776.7 ORX99589.1 - 0.052 14.5 2.3 18 6.4 3.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_22 PF13401.6 ORX99589.1 - 0.054 13.8 1.8 0.13 12.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORX99589.1 - 0.055 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORX99589.1 - 0.064 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ORX99589.1 - 0.069 12.9 0.8 0.1 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Exonuc_VII_L PF02601.15 ORX99589.1 - 0.17 11.5 7.1 0.29 10.7 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 ORX99589.1 - 0.21 10.7 7.0 0.34 10.0 7.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP_bind_1 PF03029.17 ORX99589.1 - 0.26 11.0 6.2 14 5.3 0.0 3.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 ORX99589.1 - 0.73 10.3 12.6 12 6.3 9.4 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORX99589.1 - 0.87 9.6 0.0 0.87 9.6 0.0 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain TMPIT PF07851.13 ORX99589.1 - 2.6 7.2 5.8 4.7 6.4 5.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF3987 PF13148.6 ORX99589.1 - 8.4 5.3 8.5 22 3.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PLA2G12 PF06951.11 ORX99590.1 - 1.4e-08 34.9 7.0 1.8e-08 34.5 7.0 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Ribosomal_S18 PF01084.20 ORX99591.1 - 6.9e-21 74.2 0.1 1.2e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 SRP54 PF00448.22 ORX99592.1 - 1.3e-77 259.8 0.4 1.3e-77 259.8 0.4 1.7 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ORX99592.1 - 3.1e-32 111.1 2.5 3.1e-32 111.1 2.5 4.1 3 1 1 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.19 ORX99592.1 - 7.9e-20 70.9 2.2 2.2e-19 69.4 2.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 ORX99592.1 - 3.2e-06 26.8 0.6 2.6e-05 23.9 0.2 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORX99592.1 - 6.1e-05 22.1 0.8 0.0033 16.5 0.1 3.1 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 ORX99592.1 - 6.4e-05 22.5 0.8 0.22 10.9 0.1 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit ResIII PF04851.15 ORX99592.1 - 0.00013 22.0 0.7 0.0004 20.4 0.7 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 ORX99592.1 - 0.00024 21.3 0.0 0.00056 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORX99592.1 - 0.00024 21.5 0.3 0.0021 18.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORX99592.1 - 0.00046 20.6 0.0 0.00099 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 ORX99592.1 - 0.00063 19.8 0.0 0.002 18.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 ORX99592.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 ORX99592.1 - 0.0064 16.8 0.3 0.03 14.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 ORX99592.1 - 0.0094 15.8 0.7 0.054 13.4 0.1 2.3 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 ORX99592.1 - 0.01 15.5 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORX99592.1 - 0.011 15.6 0.2 0.046 13.5 0.0 2.3 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ORX99592.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 ORX99592.1 - 0.016 15.2 0.1 0.06 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORX99592.1 - 0.025 14.6 0.2 0.16 12.1 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 ORX99592.1 - 0.025 15.1 0.1 0.081 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 ORX99592.1 - 0.064 13.0 0.1 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA PF00004.29 ORX99592.1 - 0.07 13.6 4.4 0.083 13.3 0.2 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) HMGL-like PF00682.19 ORX99592.1 - 0.079 12.5 0.5 0.43 10.1 0.1 2.1 2 0 0 2 2 2 0 HMGL-like Thymidylate_kin PF02223.17 ORX99592.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase Paramyxo_P PF01806.17 ORX99592.1 - 0.12 11.8 0.8 0.84 9.0 0.1 2.4 2 1 1 3 3 3 0 Paramyxovirinae P phosphoprotein C-terminal region Zeta_toxin PF06414.12 ORX99592.1 - 0.12 11.7 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DNA_pol3_chi PF04364.13 ORX99592.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC AAA_25 PF13481.6 ORX99592.1 - 0.22 11.1 0.2 0.77 9.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain Ribosomal_S4e PF00900.20 ORX99593.1 - 3.4e-36 123.0 0.1 7.1e-36 122.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORX99593.1 - 2.2e-26 91.2 0.1 3.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORX99593.1 - 2.8e-21 75.3 6.6 6.5e-21 74.2 6.6 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORX99593.1 - 1.3e-08 34.4 0.1 3.3e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORX99593.1 - 7.2e-05 22.6 5.4 7.2e-05 22.6 5.4 2.6 3 0 0 3 3 3 1 KOW motif NIR_SIR PF01077.22 ORX99594.1 - 6.3e-52 175.3 0.0 5e-46 156.1 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ORX99594.1 - 3.3e-33 113.3 0.1 7.3e-16 57.8 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 ORX99594.1 - 2.3e-25 89.5 0.0 8.3e-24 84.4 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin POR_N PF01855.19 ORX99594.1 - 1.3e-23 84.0 0.0 5.3e-23 82.0 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 ORX99594.1 - 2.2e-06 27.9 0.0 6.9e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF3181 PF11378.8 ORX99594.1 - 0.11 12.9 0.3 0.41 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3181) CPSF73-100_C PF11718.8 ORX99594.1 - 0.2 11.1 0.8 0.94 9.0 0.3 2.0 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MMM1 PF10296.9 ORX99595.1 - 6.5e-07 28.7 0.6 1.8e-06 27.3 0.0 1.9 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 ORX99596.1 - 3.2e-05 24.3 0.0 3.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_hydro_72 PF03198.14 ORX99597.1 - 4.6e-127 423.6 4.7 5.6e-127 423.3 4.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORX99597.1 - 9.7e-19 67.8 1.5 9.7e-19 67.8 1.5 2.5 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 ORX99597.1 - 1.8e-05 24.3 0.3 0.00033 20.2 0.3 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 ORX99597.1 - 0.081 12.0 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain GPI-anchored PF10342.9 ORX99598.1 - 7.4e-14 52.3 0.4 2.6e-13 50.6 0.2 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_61 PF03443.14 ORX99598.1 - 0.04 13.9 0.4 3.6 7.5 0.4 2.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 MFS_1 PF07690.16 ORX99599.1 - 1.1e-25 90.3 63.6 7.5e-15 54.7 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CAP PF00188.26 ORX99630.1 - 6.3e-17 62.6 0.0 8.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORX99631.1 - 1.7e-17 64.4 0.0 2.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RPA43_OB PF17875.1 ORX99632.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Redoxin PF08534.10 ORX99634.1 - 1.6e-31 109.0 0.0 1.9e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORX99634.1 - 6.5e-11 42.2 0.0 8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 ORX99634.1 - 0.022 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme G-gamma PF00631.22 ORX99635.1 - 3.7e-18 65.3 0.0 4.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain TIMELESS PF04821.14 ORX99636.1 - 1.9e-58 197.9 0.0 1.9e-58 197.9 0.0 2.9 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 ORX99636.1 - 1.5e-09 37.6 8.0 1.5e-09 37.6 8.0 4.6 3 1 1 4 4 4 1 Timeless protein C terminal region Urb2 PF10441.9 ORX99636.1 - 0.04 13.9 0.2 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Urb2/Npa2 family FKS1_dom1 PF14288.6 ORX99636.1 - 0.22 11.9 6.8 6.9 7.0 0.9 3.3 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Chordopox_A30L PF06015.12 ORX99636.1 - 0.33 10.8 0.1 0.33 10.8 0.1 3.7 3 1 1 4 4 4 0 Chordopoxvirus A30L protein AAA_lid_2 PF17863.1 ORX99637.1 - 0.018 14.8 0.1 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA lid domain SH3_1 PF00018.28 ORX99638.1 - 7.6e-16 57.5 0.1 1e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORX99638.1 - 3.1e-12 46.0 0.0 4.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORX99638.1 - 4.8e-10 39.2 0.1 6.3e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain RasGEF PF00617.19 ORX99639.1 - 1.6e-60 204.3 0.8 4.7e-60 202.8 0.1 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORX99639.1 - 9.5e-29 99.7 0.5 5.1e-28 97.4 0.6 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif WW PF00397.26 ORX99639.1 - 4.3e-06 26.7 0.6 8.2e-06 25.8 0.6 1.5 1 0 0 1 1 1 1 WW domain GIT1_C PF12205.8 ORX99639.1 - 0.00099 19.2 1.7 0.35 11.0 0.2 2.8 2 0 0 2 2 2 2 G protein-coupled receptor kinase-interacting protein 1 C term I_LWEQ PF01608.17 ORX99639.1 - 0.0031 17.8 2.4 2.1 8.6 0.8 3.5 2 1 1 3 3 3 2 I/LWEQ domain CAS_C PF12026.8 ORX99639.1 - 0.035 14.2 1.7 6.7 6.7 0.1 2.7 3 0 0 3 3 3 0 Crk-Associated Substrate C-terminal domain E1_DerP2_DerF2 PF02221.15 ORX99640.1 - 6.4e-12 46.1 0.0 8.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 ML domain EamA PF00892.20 ORX99641.1 - 6.1e-10 39.4 37.0 2.1e-06 28.0 7.3 2.9 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 ORX99641.1 - 0.029 13.6 19.6 0.12 11.6 19.6 1.9 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Phos_pyr_kin PF08543.12 ORX99642.1 - 1.6e-84 283.2 1.2 1.6e-84 283.2 1.2 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 ORX99642.1 - 5.1e-41 140.8 0.6 7.2e-41 140.3 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Mito_carr PF00153.27 ORX99643.1 - 1.7e-51 172.1 4.9 8e-19 67.4 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 ORX99644.1 - 1.6e-70 233.1 0.6 4.2e-24 84.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX99644.1 - 0.0019 17.4 0.7 1.7 7.7 0.2 3.1 2 1 1 3 3 3 2 Gammaproteobacterial serine protease FA_hydroxylase PF04116.13 ORX99645.1 - 1e-25 90.6 9.1 1e-25 90.6 9.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Caveolin PF01146.17 ORX99645.1 - 0.011 15.8 0.8 0.021 14.8 0.8 1.6 1 0 0 1 1 1 0 Caveolin Lyase_1 PF00206.20 ORX99646.1 - 3.6e-105 351.8 0.0 7.4e-105 350.8 0.0 1.5 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 ORX99646.1 - 5.7e-24 84.7 0.0 1.5e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal BCAS3 PF12490.8 ORX99647.1 - 8.2e-08 32.1 2.0 0.0026 17.4 0.3 2.8 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 3 WD40 PF00400.32 ORX99647.1 - 0.00012 22.8 1.9 0.64 11.0 0.4 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.12 ORX99647.1 - 0.0031 17.4 0.1 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 ORX99647.1 - 0.029 14.6 0.0 3.1 8.2 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TRIQK PF15168.6 ORX99648.1 - 0.067 13.1 0.8 0.14 12.0 0.8 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family DMT_YdcZ PF04657.13 ORX99649.1 - 1.7e-23 83.4 12.1 2e-23 83.2 12.1 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ Glyoxalase_4 PF13669.6 ORX99650.1 - 2e-21 76.3 0.0 2.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 ORX99650.1 - 9.7e-12 45.2 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ORX99650.1 - 2.5e-08 34.2 0.0 3.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ORX99650.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ORX99650.1 - 0.079 13.8 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Cas1_AcylT PF07779.12 ORX99651.1 - 8.3e-136 453.7 30.8 1.1e-135 453.3 30.8 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p GPS PF01825.21 ORX99651.1 - 0.017 15.6 0.4 0.017 15.6 0.4 1.9 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif PC-Esterase PF13839.6 ORX99651.1 - 0.041 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p OAD_gamma PF04277.13 ORX99651.1 - 2.6 8.7 0.0 2.6 8.7 0.0 3.9 6 0 0 6 6 6 0 Oxaloacetate decarboxylase, gamma chain RGS PF00615.19 ORX99652.1 - 9e-15 55.0 1.8 1.7e-14 54.1 1.8 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain VIT1 PF01988.19 ORX99652.1 - 0.15 11.9 2.3 0.16 11.8 1.3 1.5 1 1 0 1 1 1 0 VIT family Vut_1 PF02592.15 ORX99652.1 - 0.64 10.3 7.9 0.13 12.6 3.6 1.9 2 0 0 2 2 2 0 Putative vitamin uptake transporter CoA_binding_2 PF13380.6 ORX99655.1 - 2.7e-26 92.3 0.0 3.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 ORX99655.1 - 0.019 15.6 0.0 0.025 15.2 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain PH PF00169.29 ORX99656.1 - 0.12 12.9 0.1 0.43 11.1 0.1 2.0 1 1 0 1 1 1 0 PH domain UCH PF00443.29 ORX99657.1 - 1e-51 175.9 0.9 1.3e-51 175.5 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX99657.1 - 3.8e-24 85.9 5.6 1.5e-23 83.9 5.6 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORX99657.1 - 3.2e-13 49.8 9.7 3.2e-13 49.8 9.7 3.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.6 ORX99657.1 - 0.17 11.4 5.5 23 4.6 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ORX99657.1 - 5.1 7.3 9.4 2.6 8.2 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Ribosomal_L13 PF00572.18 ORX99658.1 - 8.4e-11 42.2 0.1 8.7e-09 35.7 0.0 2.8 2 1 0 2 2 2 1 Ribosomal protein L13 RNA_pol_Rpc4 PF05132.14 ORX99659.1 - 6.2e-27 94.9 6.4 7.1e-27 94.7 1.5 3.1 2 1 0 2 2 2 1 RNA polymerase III RPC4 Inhibitor_I9 PF05922.16 ORX99660.1 - 1.6e-06 28.7 0.2 3.1e-06 27.8 0.2 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 GTP_cyclohydroI PF01227.22 ORX99661.1 - 6.7e-78 260.2 0.3 8.1e-78 259.9 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ORX99661.1 - 0.0014 18.7 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 ORX99661.1 - 0.033 13.5 0.1 0.078 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) AFT PF08731.11 ORX99661.1 - 0.067 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor AFT DUF5410 PF17422.2 ORX99662.1 - 0.024 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5410) Baculo_11_kDa PF06143.11 ORX99662.1 - 0.15 11.6 0.6 2.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family C2 PF00168.30 ORX99664.1 - 1.1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain U-box PF04564.15 ORX99665.1 - 1.1e-17 64.0 0.1 2.4e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 U-box domain Polysacc_deac_1 PF01522.21 ORX99666.1 - 1.9e-24 85.9 0.0 3.4e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 ORX99666.1 - 0.0025 17.0 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase Glyco_transf_28 PF03033.20 ORX99667.1 - 0.0072 16.4 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain MFS_1 PF07690.16 ORX99705.1 - 1.9e-51 175.1 48.6 1.9e-51 175.1 48.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORX99705.1 - 4.6e-16 58.4 25.1 6.4e-16 57.9 25.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORX99705.1 - 2.1e-13 50.0 12.9 2.1e-13 50.0 12.9 3.6 2 1 1 4 4 4 1 Sugar (and other) transporter Carb_anhydrase PF00194.21 ORX99706.1 - 2e-44 152.1 1.0 2.9e-44 151.5 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Peptidase_C1_2 PF03051.15 ORX99707.1 - 1.1e-185 617.6 2.6 1.3e-185 617.4 2.6 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ORX99707.1 - 3.1e-06 27.4 0.0 0.0015 18.7 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease HMG_box PF00505.19 ORX99708.1 - 6.3e-19 68.2 0.5 7e-19 68.0 0.5 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORX99708.1 - 6e-05 23.6 0.3 6.5e-05 23.5 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain IBR PF01485.21 ORX99710.1 - 7.1e-08 32.6 45.8 2.5e-05 24.4 16.2 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORX99710.1 - 0.0004 20.2 6.9 0.0004 20.2 6.9 5.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Peptidase_C69 PF03577.15 ORX99710.1 - 0.039 12.9 0.1 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase family C69 DUF3287 PF11690.8 ORX99710.1 - 0.097 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Transket_pyr PF02779.24 ORX99711.1 - 2.2e-66 222.9 0.0 3.2e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORX99711.1 - 1.6e-52 177.2 0.0 2.9e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORX99711.1 - 1.6e-51 175.0 0.0 7e-51 172.9 0.0 1.9 1 1 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 ORX99711.1 - 2.8e-20 71.6 1.2 4.5e-20 71.0 0.3 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus SNARE_assoc PF09335.11 ORX99712.1 - 6.6e-08 33.1 1.0 6.6e-08 33.1 1.0 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein 14-3-3 PF00244.20 ORX99713.1 - 7.1e-107 356.0 6.9 8.5e-107 355.7 6.9 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 ORX99713.1 - 0.02 14.9 0.2 0.045 13.7 0.2 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Peptidase_C98 PF15499.6 ORX99713.1 - 0.041 13.4 0.1 0.077 12.5 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Sec7 PF01369.20 ORX99714.1 - 2e-34 118.9 0.1 3.4e-34 118.1 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORX99714.1 - 9.8e-16 58.2 0.4 2.7e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORX99714.1 - 7.5e-13 48.9 0.2 1.9e-12 47.6 0.2 1.7 1 0 0 1 1 1 1 PH domain DnaJ-X PF14308.6 ORX99715.1 - 1.1e-52 178.5 0.0 1.1e-52 178.5 0.0 2.3 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORX99715.1 - 1.4e-24 86.0 2.3 3.3e-24 84.8 2.3 1.7 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.16 ORX99715.1 - 0.16 10.8 0.6 0.2 10.6 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RLL PF10036.9 ORX99715.1 - 0.28 11.0 5.2 0.11 12.4 1.8 1.9 1 1 1 2 2 2 0 RNA transcription, translation and transport factor protein SpoIIIAH PF12685.7 ORX99715.1 - 1.9 8.2 17.2 13 5.6 17.2 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein SabA_adhesion PF18304.1 ORX99715.1 - 3.9 6.6 6.9 2.3 7.4 0.1 2.7 2 1 1 3 3 3 0 SabA N-terminal extracellular adhesion domain SIR2 PF02146.17 ORX99716.1 - 8.6e-64 214.7 0.0 1.1e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 ORX99716.1 - 6.7e-05 22.7 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 ORX99716.1 - 0.0047 16.7 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF2797 PF10977.8 ORX99716.1 - 0.091 12.6 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) CutC PF03932.14 ORX99716.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 CutC family DER1 PF04511.15 ORX99718.1 - 1.8e-54 184.6 12.0 2.1e-54 184.4 12.0 1.0 1 0 0 1 1 1 1 Der1-like family TPR_14 PF13428.6 ORX99719.1 - 0.086 13.7 0.0 21 6.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S24e PF01282.19 ORX99720.1 - 1.1e-38 131.0 1.3 1.3e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e UPF0176_N PF17773.1 ORX99721.1 - 8.3e-19 67.7 0.0 1.9e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 ORX99721.1 - 3.5e-06 27.3 0.1 1.1e-05 25.8 0.1 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 ORX99721.1 - 5.9e-06 26.8 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain SWC7 PF17330.2 ORX99721.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Acetyltransf_1 PF00583.25 ORX99722.1 - 7.4e-14 52.0 0.1 1.4e-13 51.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX99722.1 - 3.2e-10 40.0 0.0 3.3e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORX99722.1 - 7.3e-07 29.5 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORX99722.1 - 0.00035 20.5 0.0 0.001 19.0 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORX99722.1 - 0.0024 18.0 0.0 0.0073 16.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORX99722.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ORX99722.1 - 0.032 13.7 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF4543 PF15076.6 ORX99722.1 - 0.041 14.0 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Oxidored_FMN PF00724.20 ORX99722.1 - 0.091 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family PH PF00169.29 ORX99723.1 - 2.1e-08 34.6 0.0 5.8e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 ORX99723.1 - 0.023 15.1 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Cell division protein anillin Zn_clus PF00172.18 ORX99724.1 - 4.7e-14 52.2 9.5 6.1e-14 51.9 9.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 ORX99724.1 - 1.5 9.2 8.5 1.3 9.4 2.2 2.1 1 1 1 2 2 2 0 Opy2 protein DUF1771 PF08590.10 ORX99727.1 - 1.1e-19 70.6 10.0 1.9e-19 69.8 10.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORX99727.1 - 2.2e-13 50.4 0.2 4.4e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 Smr domain Seryl_tRNA_N PF02403.22 ORX99727.1 - 1 9.6 4.1 0.71 10.1 2.1 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain 4HBT PF03061.22 ORX99728.1 - 1.8e-12 47.4 0.0 2.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ORX99728.1 - 0.0018 18.6 0.0 0.069 13.4 0.0 1.8 1 1 1 2 2 2 2 Thioesterase-like superfamily FeThRed_A PF02941.15 ORX99728.1 - 0.0032 17.6 0.1 0.52 10.5 0.0 2.3 2 0 0 2 2 2 2 Ferredoxin thioredoxin reductase variable alpha chain ANAPC4_WD40 PF12894.7 ORX99729.1 - 3.5e-16 59.3 0.1 0.006 16.8 0.0 6.5 2 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORX99729.1 - 3.8e-14 53.0 0.7 3.6e-06 27.0 0.0 5.4 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORX99729.1 - 8.2e-10 39.1 3.4 0.0018 19.1 0.0 7.4 7 1 0 7 7 7 2 WD domain, G-beta repeat IKI3 PF04762.12 ORX99729.1 - 3.2e-05 22.2 0.3 0.00035 18.7 0.3 2.2 1 1 0 1 1 1 1 IKI3 family DPPIV_N PF00930.21 ORX99729.1 - 0.00018 20.4 0.6 0.63 8.7 0.0 4.8 3 2 2 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.11 ORX99729.1 - 0.026 14.3 0.0 39 4.1 0.0 3.4 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal PD40 PF07676.12 ORX99729.1 - 0.044 13.7 0.7 1.2e+02 2.7 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 ORX99729.1 - 0.053 12.6 0.2 1.1 8.3 0.1 3.1 2 2 0 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 ORX99729.1 - 0.1 11.1 0.0 6 5.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Lactonase PF10282.9 ORX99729.1 - 0.17 11.1 0.0 1.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller NTF2 PF02136.20 ORX99730.1 - 2.3e-20 73.4 0.0 2.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 ORX99730.1 - 7.4e-10 39.0 0.0 9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SNF2_N PF00176.23 ORX99732.1 - 9.4e-61 205.5 0.2 2.2e-60 204.3 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 ORX99732.1 - 1.5e-18 66.5 7.9 6.1e-12 45.3 1.0 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ORX99732.1 - 2.5e-17 63.2 0.0 8.3e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORX99732.1 - 5.6e-09 36.2 0.0 5.6e-09 36.2 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORX99732.1 - 0.00023 21.0 0.0 0.00078 19.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 ORX99732.1 - 0.00046 20.3 0.4 0.0047 17.1 0.2 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 ORX99732.1 - 0.12 12.4 0.1 0.12 12.4 0.1 4.5 5 0 0 5 5 5 0 SLIDE Choline_transpo PF04515.12 ORX99733.1 - 2.5e-19 69.7 7.5 3e-19 69.4 7.5 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter Saf_2TM PF18303.1 ORX99733.1 - 1.6 8.3 5.5 0.21 11.2 1.7 1.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Vps54 PF07928.12 ORX99734.1 - 4.7e-54 182.4 1.4 1.6e-53 180.7 1.4 2.0 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 ORX99734.1 - 1.2e-11 44.4 0.1 1.2e-11 44.4 0.1 2.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex UCH PF00443.29 ORX99735.1 - 2.5e-53 181.2 1.4 2.5e-53 181.2 1.4 1.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORX99735.1 - 2e-24 86.8 1.6 3.9e-24 85.8 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc-ribbons_6 PF07191.12 ORX99735.1 - 0.04 13.9 0.3 0.12 12.3 0.3 1.8 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 ORX99735.1 - 0.11 12.1 1.7 0.55 9.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LRR_4 PF12799.7 ORX99736.1 - 0.034 14.6 8.9 1.9 9.0 0.0 5.7 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORX99736.1 - 0.11 12.2 3.4 17 5.3 0.0 4.8 5 2 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 ORX99736.1 - 7.1 7.0 8.6 33 4.9 0.0 5.5 8 0 0 8 8 8 0 Leucine Rich repeat BPL_LplA_LipB PF03099.19 ORX99737.1 - 0.0022 17.9 0.2 0.4 10.6 0.0 2.2 1 1 1 2 2 2 2 Biotin/lipoate A/B protein ligase family WD40 PF00400.32 ORX99738.1 - 5.3e-12 46.1 0.1 0.022 15.6 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99738.1 - 2.7e-08 34.0 0.0 0.13 12.6 0.0 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 ORX99738.1 - 6.5e-05 22.4 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 ORX99738.1 - 0.001 18.5 1.1 0.06 12.7 0.1 2.9 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 ORX99738.1 - 0.0079 14.9 0.0 2.9 6.4 0.0 3.3 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORX99738.1 - 0.041 12.9 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Membralin PF09746.9 ORX99738.1 - 1.4 7.9 3.2 2.6 7.0 3.2 1.4 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 ORX99738.1 - 3.7 6.2 7.2 5.1 5.7 7.2 1.2 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 ORX99738.1 - 8.7 5.2 9.5 13 4.6 9.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SOSSC PF15925.5 ORX99739.1 - 0.0037 18.5 0.2 0.0048 18.2 0.2 1.2 1 0 0 1 1 1 1 SOSS complex subunit C Ribosomal_L44 PF00935.19 ORX99740.1 - 3.9e-37 126.6 11.0 5.7e-37 126.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Myb_DNA-bind_4 PF13837.6 ORX99741.1 - 9.6e-16 58.0 2.6 9.6e-16 58.0 2.6 2.6 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain FliD_C PF07195.12 ORX99741.1 - 0.00095 18.7 0.5 0.00095 18.7 0.5 2.1 2 1 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus MADF_DNA_bdg PF10545.9 ORX99741.1 - 0.0015 18.8 1.2 0.0015 18.8 1.2 3.1 4 0 0 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 ORX99741.1 - 0.0048 17.1 0.9 0.014 15.6 0.9 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Jnk-SapK_ap_N PF09744.9 ORX99741.1 - 0.32 11.2 37.8 0.16 12.2 15.1 2.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Ion_trans PF00520.31 ORX99742.1 - 8.2e-09 35.0 7.2 9.9e-09 34.8 7.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ribosomal_L7Ae PF01248.26 ORX99743.1 - 6e-27 93.2 0.0 7.2e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ORX99743.1 - 0.00088 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 ORX99743.1 - 0.01 15.9 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 MatP_C PF17414.2 ORX99743.1 - 0.2 11.8 1.3 0.78 10.0 0.2 2.3 2 1 1 3 3 3 0 MatP C-terminal ribbon-helix-helix domain DUF2052 PF09747.9 ORX99747.1 - 2.7e-18 66.8 7.7 3.4e-18 66.5 7.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) HMG_box_2 PF09011.10 ORX99748.1 - 0.00024 21.6 0.0 0.00033 21.2 0.0 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 ORX99748.1 - 0.086 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box MAP17 PF15807.5 ORX99749.1 - 0.29 11.4 1.2 15 5.8 0.2 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 YvrJ PF12841.7 ORX99749.1 - 0.88 9.2 3.7 0.41 10.2 0.2 2.2 2 0 0 2 2 2 0 YvrJ protein family Metallophos PF00149.28 ORX99750.1 - 3.5e-36 125.6 0.1 6.8e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 ORX99750.1 - 0.12 12.1 0.9 4 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) TRIC PF05197.13 ORX99751.1 - 6.7e-14 51.9 0.7 1.1e-13 51.2 0.7 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 ORX99751.1 - 0.00046 20.0 1.4 0.01 15.7 0.4 2.4 2 0 0 2 2 2 1 UPF0126 domain RabGAP-TBC PF00566.18 ORX99752.1 - 3e-47 161.1 12.7 7.2e-46 156.6 12.7 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Thioesterase PF00975.20 ORX99753.1 - 2.3e-28 99.9 0.0 7.5e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain HAUS4 PF14735.6 ORX99753.1 - 1.7e-15 57.4 6.5 6.9e-15 55.4 6.5 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Abhydrolase_6 PF12697.7 ORX99753.1 - 0.00036 21.2 0.0 0.00054 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORX99753.1 - 0.0037 16.6 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Syntaxin_2 PF14523.6 ORX99753.1 - 0.024 15.0 1.0 0.024 15.0 1.0 2.6 3 0 0 3 3 3 0 Syntaxin-like protein Abhydrolase_1 PF00561.20 ORX99753.1 - 0.037 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 ORX99753.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain HsbA PF12296.8 ORX99753.1 - 0.22 12.0 2.2 0.36 11.3 0.1 2.4 3 1 0 3 3 3 0 Hydrophobic surface binding protein A DUF16 PF01519.16 ORX99753.1 - 8.6 6.9 7.5 38 4.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Pkinase PF00069.25 ORX99761.1 - 2.9e-52 177.7 0.0 4.1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99761.1 - 6.7e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORX99761.1 - 7.7e-05 22.7 0.2 0.00016 21.7 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORX99761.1 - 0.0019 17.9 0.1 1.1 8.8 0.1 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORX99761.1 - 0.0046 15.9 0.1 0.0077 15.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORX99761.1 - 0.078 12.3 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORX99761.1 - 0.13 11.5 0.1 0.2 11.0 0.1 1.5 1 1 0 1 1 1 0 Kinase-like SR-25 PF10500.9 ORX99761.1 - 1.1 8.8 5.0 0.7 9.5 3.4 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_zinc_N PF00107.26 ORX99762.1 - 1.4e-21 76.8 0.0 2.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORX99762.1 - 1.4e-15 57.1 0.1 2.9e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX99762.1 - 5.6e-07 30.7 0.0 1.6e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase lci PF12197.8 ORX99762.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein ADH_zinc_N PF00107.26 ORX99763.1 - 3.7e-21 75.5 0.0 5.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORX99763.1 - 9.6e-16 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX99763.1 - 2.7e-07 31.7 0.0 7.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Adhesin_P1_N PF18652.1 ORX99763.1 - 0.15 12.1 0.1 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain ADH_zinc_N PF00107.26 ORX99764.1 - 3.7e-21 75.4 0.0 5.9e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORX99764.1 - 9.6e-16 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORX99764.1 - 2.7e-07 31.7 0.0 7.6e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Adhesin_P1_N PF18652.1 ORX99764.1 - 0.15 12.1 0.1 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Mito_carr PF00153.27 ORX99765.1 - 4.3e-65 215.7 1.5 1.3e-21 76.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORX99765.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Gammaproteobacterial serine protease HSP70 PF00012.20 ORX99766.1 - 1.1e-256 852.8 10.0 1.2e-256 852.6 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORX99766.1 - 1.7e-18 66.6 0.5 2.4e-17 62.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 ORX99766.1 - 0.00023 21.5 2.2 0.57 10.6 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 ORX99766.1 - 0.0023 17.3 2.5 0.021 14.1 0.1 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Spore_GerAC PF05504.11 ORX99766.1 - 0.0085 16.3 8.1 0.45 10.7 0.1 3.4 3 0 0 3 3 3 2 Spore germination B3/ GerAC like, C-terminal DUF5611 PF18446.1 ORX99766.1 - 0.31 11.9 4.4 0.95 10.4 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5611) zf-C2H2_2 PF12756.7 ORX99767.1 - 5.1e-37 126.3 19.0 1.4e-31 108.8 0.8 3.6 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORX99767.1 - 9.3e-11 41.7 18.7 1.7e-09 37.7 4.2 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORX99767.1 - 2.1e-07 31.1 2.2 2.1e-07 31.1 2.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORX99767.1 - 0.0051 16.7 3.2 0.57 10.1 0.2 2.8 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger CRA PF06589.11 ORX99767.1 - 0.024 14.8 0.8 0.059 13.5 0.8 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) zf-3CxxC_2 PF17180.4 ORX99767.1 - 0.036 14.8 1.2 0.16 12.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-binding domain zf-C2H2_4 PF13894.6 ORX99767.1 - 0.036 14.9 16.4 0.78 10.8 0.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger DUF629 PF04780.12 ORX99767.1 - 0.042 12.4 6.9 1.2 7.6 0.9 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF629) DUF1460 PF07313.12 ORX99767.1 - 0.059 12.7 1.3 0.19 11.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1460) YyzF PF14116.6 ORX99767.1 - 0.06 13.4 0.3 0.62 10.1 0.3 2.7 2 0 0 2 2 2 0 YyzF-like protein zf-C2H2 PF00096.26 ORX99767.1 - 0.22 12.0 19.9 0.74 10.4 0.3 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.12 ORX99767.1 - 0.24 11.6 7.8 4.8 7.4 3.1 2.6 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF2024 PF09630.10 ORX99767.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) TFIIS_C PF01096.18 ORX99767.1 - 5.3 7.0 6.0 10 6.1 0.2 3.2 4 0 0 4 4 3 0 Transcription factor S-II (TFIIS) zf-C2H2_6 PF13912.6 ORX99767.1 - 9.1 6.4 7.9 21 5.3 0.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger HNH_5 PF14279.6 ORX99767.1 - 9.5 6.2 11.4 2.3 8.1 0.3 3.7 4 0 0 4 4 4 0 HNH endonuclease FAT PF02259.23 ORX99768.1 - 2.9e-135 450.9 0.9 6.3e-135 449.8 0.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 ORX99768.1 - 1.1e-75 254.7 0.2 2.2e-75 253.7 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 ORX99768.1 - 1.7e-53 180.8 2.4 5.2e-51 172.8 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 ORX99768.1 - 3.3e-46 155.7 0.9 3.3e-46 155.7 0.9 2.5 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain HEAT PF02985.22 ORX99768.1 - 6.1e-19 66.5 13.8 0.00036 20.5 0.0 11.8 12 0 0 12 12 9 2 HEAT repeat FATC PF02260.20 ORX99768.1 - 1e-16 60.4 1.2 3.7e-16 58.6 1.2 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 ORX99768.1 - 6.4e-14 52.1 17.0 0.012 16.0 0.0 8.9 8 2 3 11 11 10 4 HEAT repeats HEAT_EZ PF13513.6 ORX99768.1 - 1e-09 38.7 24.7 1.4e-05 25.5 0.1 10.9 10 2 2 12 12 10 2 HEAT-like repeat Adaptin_N PF01602.20 ORX99768.1 - 7.5e-09 34.7 2.8 0.001 17.8 0.2 3.5 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 ORX99768.1 - 2e-07 31.2 1.0 0.0063 16.6 0.0 5.4 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 ORX99768.1 - 3.8e-06 27.3 0.3 1.2 9.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 ORX99768.1 - 4.8e-06 27.1 1.2 22 5.7 0.0 7.1 5 2 0 6 6 6 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 ORX99768.1 - 0.00047 19.8 10.4 0.84 9.1 0.7 5.7 3 1 2 5 5 5 2 Tti2 family CLASP_N PF12348.8 ORX99768.1 - 0.00053 19.6 8.8 0.9 9.1 0.0 5.9 5 3 1 6 6 6 2 CLASP N terminal Sec7_N PF12783.7 ORX99768.1 - 0.0014 18.5 2.6 0.78 9.6 0.0 4.6 3 2 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.6 ORX99768.1 - 0.0034 17.3 1.9 2.2 8.5 0.1 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORX99768.1 - 0.019 15.2 0.6 5.7 7.2 0.0 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RICTOR_V PF14668.6 ORX99768.1 - 0.068 13.4 0.0 4.8 7.5 0.0 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 MMS19_C PF12460.8 ORX99768.1 - 0.07 12.2 5.3 0.53 9.3 0.2 3.5 1 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.7 ORX99768.1 - 0.11 12.8 6.1 0.39 11.1 0.0 4.6 5 0 0 5 5 4 0 HEAT repeat associated with sister chromatid cohesion TPR_1 PF00515.28 ORX99768.1 - 0.14 12.0 4.0 5.3 7.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORX99768.1 - 0.17 12.1 5.2 13 6.2 0.3 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat UME PF08064.13 ORX99768.1 - 0.23 11.4 4.0 1.6 8.7 0.1 4.5 5 0 0 5 5 4 0 UME (NUC010) domain DUF3437 PF11919.8 ORX99768.1 - 1.7 8.6 5.7 8.4 6.4 0.0 4.6 5 0 0 5 5 3 0 Domain of unknown function (DUF3437) TPR_16 PF13432.6 ORX99768.1 - 2.2 9.0 5.6 9.7 6.9 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 ORX99768.1 - 6.5 7.7 5.6 42 5.2 0.0 4.8 3 1 1 4 4 2 0 PBS lyase HEAT-like repeat COG5 PF10392.9 ORX99769.1 - 4.4e-23 81.9 1.5 4.4e-23 81.9 1.5 2.8 3 0 0 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 ORX99769.1 - 0.00049 20.2 2.9 0.00049 20.2 2.9 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 ORX99769.1 - 0.00085 19.2 0.8 0.037 13.9 0.1 3.1 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps54_N PF10475.9 ORX99769.1 - 0.0015 17.9 0.8 0.0015 17.9 0.8 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Baculo_PEP_C PF04513.12 ORX99769.1 - 0.043 13.9 5.3 0.7 9.9 0.2 4.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 ORX99769.1 - 0.21 11.6 2.1 0.87 9.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 ORX99769.1 - 0.24 11.0 6.9 3.7 7.1 0.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) CDC45 PF02724.14 ORX99770.1 - 9.1e-210 698.2 14.6 2.6e-160 534.8 6.6 2.0 1 1 1 2 2 2 2 CDC45-like protein CPSase_L_D3 PF02787.19 ORX99770.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Cpn10 PF00166.21 ORX99771.1 - 5.9e-32 109.6 0.0 6.6e-32 109.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 ORX99772.1 - 1.6e-84 284.3 9.6 2.3e-84 283.8 9.6 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SnoaL_4 PF13577.6 ORX99772.1 - 0.14 12.3 0.1 0.81 9.8 0.1 2.3 3 0 0 3 3 3 0 SnoaL-like domain ENTH PF01417.20 ORX99773.1 - 1.4e-49 167.3 0.0 4.6e-49 165.6 0.0 1.9 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 ORX99773.1 - 2.3e-06 26.8 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 ORX99773.1 - 4.1e-06 26.3 2.7 0.0082 16.0 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif VHS PF00790.19 ORX99773.1 - 0.037 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF4200 PF13863.6 ORX99773.1 - 5.4 7.4 12.4 0.3 11.5 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WD40 PF00400.32 ORX99774.1 - 2.8e-18 65.9 0.0 1.9e-06 28.5 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORX99774.1 - 3.8e-13 49.6 0.0 0.00097 19.4 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 ORX99774.1 - 0.035 14.0 0.9 0.25 11.3 0.3 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 ORX99774.1 - 0.044 13.1 0.0 13 5.0 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain eIF2A PF08662.11 ORX99774.1 - 0.11 12.4 0.0 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A HSCB_C PF07743.13 ORX99775.1 - 5.6e-19 68.4 6.2 5.6e-19 68.4 6.2 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ORX99775.1 - 1e-06 28.8 2.6 1.9e-06 27.9 0.9 2.3 2 1 0 2 2 2 1 DnaJ domain Coa1 PF08695.10 ORX99776.1 - 2.8e-29 101.2 0.0 4.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Gram_pos_anchor PF00746.21 ORX99776.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HEAT_EZ PF13513.6 ORX99777.1 - 6.2e-37 125.6 14.4 1.9e-13 50.6 0.0 11.8 10 3 4 14 14 14 7 HEAT-like repeat HEAT PF02985.22 ORX99777.1 - 4e-27 92.0 12.1 6.8e-05 22.8 0.0 11.0 12 0 0 12 12 10 5 HEAT repeat HEAT_2 PF13646.6 ORX99777.1 - 2e-20 73.0 0.2 0.0078 16.6 0.0 7.7 4 3 4 8 8 8 7 HEAT repeats Cnd1 PF12717.7 ORX99777.1 - 1.5e-14 54.4 0.0 0.0068 16.5 0.0 4.8 3 1 1 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORX99777.1 - 2.3e-12 47.4 0.0 0.0062 17.1 0.0 6.2 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 ORX99777.1 - 2.1e-10 40.4 0.4 2.1e-09 37.2 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 ORX99777.1 - 7.3e-10 38.5 7.6 0.0066 16.5 0.0 6.3 7 0 0 7 7 6 3 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 ORX99777.1 - 9.9e-08 31.5 4.3 0.013 14.6 0.0 4.0 3 2 0 3 3 3 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 ORX99777.1 - 2.3e-07 29.8 0.0 0.33 9.4 0.1 4.8 3 2 1 4 4 4 3 Adaptin N terminal region Tti2 PF10521.9 ORX99777.1 - 7.7e-05 22.4 0.4 1.6 8.2 0.0 4.7 4 2 3 7 7 6 2 Tti2 family DUF3437 PF11919.8 ORX99777.1 - 0.0016 18.3 0.0 11 6.0 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 ORX99777.1 - 0.0025 18.0 0.0 0.049 13.8 0.0 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 ORX99777.1 - 0.011 14.2 0.1 0.18 10.3 0.0 2.9 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus Ecm29 PF13001.7 ORX99777.1 - 0.013 14.2 0.2 1.3 7.6 0.0 3.1 3 1 0 3 3 3 0 Proteasome stabiliser TIP120 PF08623.10 ORX99777.1 - 0.02 14.7 0.0 4.6 7.0 0.0 3.5 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) ParcG PF10274.9 ORX99777.1 - 0.023 14.8 0.1 8.1 6.5 0.0 3.9 4 0 0 4 4 4 0 Parkin co-regulated protein Proteasom_PSMB PF10508.9 ORX99777.1 - 0.024 13.1 0.0 0.067 11.7 0.0 1.8 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Cohesin_HEAT PF12765.7 ORX99777.1 - 0.08 13.3 0.8 52 4.3 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion UME PF08064.13 ORX99777.1 - 0.098 12.6 0.0 42 4.1 0.0 3.9 2 1 0 2 2 2 0 UME (NUC010) domain V-ATPase_H_C PF11698.8 ORX99777.1 - 0.12 12.5 0.0 4.4 7.5 0.0 2.9 2 0 0 2 2 2 0 V-ATPase subunit H Lectin_leg-like PF03388.13 ORX99778.1 - 1.9e-64 217.2 0.0 2.3e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ORX99778.1 - 6.3e-07 29.2 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain PH PF00169.29 ORX99779.1 - 2.7e-13 50.3 0.2 3e-10 40.6 0.0 2.9 1 1 0 2 2 2 2 PH domain PH_6 PF15406.6 ORX99779.1 - 1.9e-09 37.8 0.1 1.9e-09 37.8 0.1 3.4 5 0 0 5 5 5 1 Pleckstrin homology domain PH_3 PF14593.6 ORX99779.1 - 0.028 14.5 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 PH domain PH_9 PF15410.6 ORX99779.1 - 0.028 14.8 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 ORX99779.1 - 0.093 13.2 0.6 0.58 10.6 0.6 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Siva PF05458.12 ORX99780.1 - 2.1e-08 34.0 26.5 2.5e-06 27.3 25.3 2.2 1 1 1 2 2 2 2 Cd27 binding protein (Siva) Pept_tRNA_hydro PF01195.19 ORX99781.1 - 4.2e-35 121.2 0.0 4.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase TAF8_C PF10406.9 ORX99782.1 - 1.1e-18 67.5 2.2 2.7e-18 66.2 2.2 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 ORX99782.1 - 2.6e-17 62.6 0.0 3.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 ORX99782.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP_like PF17027.5 ORX99782.1 - 0.02 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Histone-fold protein Rad60-SLD PF11976.8 ORX99783.1 - 1.6e-25 88.7 0.0 1.8e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORX99783.1 - 8.8e-14 51.0 0.0 1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family BCIP PF13862.6 ORX99784.1 - 8.2e-75 251.1 0.7 1.1e-74 250.7 0.7 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Gtr1_RagA PF04670.12 ORX99785.1 - 5.1e-74 248.5 1.0 6.5e-74 248.2 1.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 ORX99785.1 - 3.6e-05 23.3 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORX99785.1 - 0.0032 17.7 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORX99785.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORX99785.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ORX99785.1 - 0.15 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AA_kinase PF00696.28 ORX99786.1 - 2.2e-39 135.5 0.2 3.2e-39 135.0 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORX99786.1 - 3.4e-17 62.2 0.4 3.4e-17 62.2 0.4 1.9 2 0 0 2 2 2 1 PUA domain DUF3477 PF11963.8 ORX99786.1 - 0.076 12.2 0.0 0.91 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3477) Hat1_N PF10394.9 ORX99787.1 - 6.9e-50 169.4 0.4 1.4e-49 168.4 0.4 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 ORX99787.1 - 6.5e-07 29.6 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORX99787.1 - 0.01 15.8 0.0 0.074 13.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain eIF3_subunit PF08597.10 ORX99787.1 - 0.057 13.3 1.3 0.18 11.7 0.2 2.0 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Pantoate_transf PF02548.15 ORX99788.1 - 6e-112 373.2 0.1 7e-112 373.0 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase DUF2012 PF09430.10 ORX99788.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Ofd1_CTDD PF10637.9 ORX99789.1 - 8.8e-81 271.0 0.0 1.2e-77 260.7 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORX99789.1 - 1.1e-29 102.9 0.0 2.9e-29 101.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORX99789.1 - 6.6e-16 59.0 0.0 1.2e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Arc_PepC PF06819.11 ORX99789.1 - 0.046 13.9 0.1 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain ATP-synt_ab PF00006.25 ORX99790.1 - 7.6e-62 208.7 0.0 1.1e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORX99790.1 - 9.6e-23 80.5 0.9 2.2e-22 79.4 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ORX99790.1 - 0.015 14.7 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ORX99790.1 - 0.023 13.9 0.8 0.057 12.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 ORX99790.1 - 0.048 13.6 0.2 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 ORX99790.1 - 0.058 13.7 0.8 0.44 10.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORX99790.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Med2 PF11214.8 ORX99790.1 - 0.081 13.1 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 NACHT PF05729.12 ORX99790.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 ORX99790.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP-synt_DE_N PF02823.16 ORX99791.1 - 5.6e-16 58.2 0.1 7.8e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain FAD_binding_3 PF01494.19 ORX99792.1 - 4.8e-22 78.7 0.0 2.3e-21 76.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORX99792.1 - 1.7e-07 30.8 0.0 0.0022 17.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX99792.1 - 1.5e-05 24.8 0.0 0.089 12.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORX99792.1 - 8.3e-05 22.7 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORX99792.1 - 0.00027 21.5 0.1 0.075 13.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORX99792.1 - 0.0016 17.6 0.0 0.016 14.3 0.0 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORX99792.1 - 0.021 14.8 0.0 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Peptidase_S9 PF00326.21 ORX99793.1 - 8.9e-52 175.6 0.0 1.3e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORX99793.1 - 1e-05 25.3 5.6 0.01 15.8 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 ORX99793.1 - 0.0062 15.3 1.4 0.14 10.9 0.8 2.8 1 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9_N PF02897.15 ORX99793.1 - 0.022 13.6 0.3 0.053 12.3 0.3 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_1 PF00561.20 ORX99793.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lactonase PF10282.9 ORX99793.1 - 0.062 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller CBAH PF02275.18 ORX99832.1 - 0.02 14.5 0.2 0.029 14.0 0.2 1.2 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family DLH PF01738.18 ORX99833.1 - 1.7e-06 27.7 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORX99833.1 - 1.5e-05 24.8 0.0 5.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORX99833.1 - 1.7e-05 24.4 0.0 0.00051 19.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORX99833.1 - 0.00028 20.3 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 ORX99833.1 - 0.0031 16.3 0.1 0.0084 14.8 0.1 1.6 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) ADH_N PF08240.12 ORX99834.1 - 1.4e-27 95.7 2.8 2.3e-27 95.0 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORX99834.1 - 3.5e-20 72.3 0.0 7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORX99834.1 - 4.9e-05 24.4 0.0 8.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORX99834.1 - 0.0029 16.9 0.2 0.0046 16.3 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORX99834.1 - 0.044 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.19 ORX99834.1 - 0.11 13.2 0.2 0.34 11.6 0.1 1.8 1 1 1 2 2 2 0 CoA binding domain TrkA_N PF02254.18 ORX99834.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 ORX99834.1 - 0.13 13.1 0.0 0.36 11.7 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Corona_I PF03187.14 ORX99834.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein ADH_N_2 PF16884.5 ORX99834.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase NUDIX PF00293.28 ORX99835.1 - 2.8e-17 63.0 0.0 3.5e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Sas10_Utp3 PF04000.15 ORX99836.1 - 1.9e-19 70.1 0.4 1.9e-19 70.1 0.4 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RelA_SpoT PF04607.17 ORX99836.1 - 0.23 11.7 2.5 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins AMP-binding PF00501.28 ORX99837.1 - 1.4e-93 313.8 0.0 1.8e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORX99837.1 - 3.4e-25 88.8 0.3 1.3e-24 86.9 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORX99837.1 - 1.5e-22 79.3 0.5 3.2e-22 78.2 0.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Sedlin_N PF04628.13 ORX99838.1 - 1.2e-30 106.3 0.2 1.4e-30 106.1 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORX99838.1 - 0.016 15.2 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family CNOT1_CAF1_bind PF16415.5 ORX99838.1 - 0.044 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DNA_methylase PF00145.17 ORX99839.1 - 2.2e-47 162.1 0.0 2.6e-46 158.5 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 ORX99839.1 - 2.7e-24 85.4 1.6 1.9e-11 43.9 0.1 3.5 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.8 ORX99839.1 - 5.9e-17 62.0 0.1 1.8e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain PsaD PF02531.16 ORX99839.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 PsaD DTHCT PF08070.11 ORX99839.1 - 0.1 13.4 9.1 0.7 10.6 4.0 2.8 2 0 0 2 2 2 0 DTHCT (NUC029) region FA_hydroxylase PF04116.13 ORX99840.1 - 1e-25 90.6 20.5 1e-25 90.6 20.5 1.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily URO-D PF01208.17 ORX99841.1 - 1e-133 445.8 0.0 1.2e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) UDPGP PF01704.18 ORX99842.1 - 1.8e-54 185.0 0.0 2.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORX99842.1 - 0.025 14.9 0.0 0.066 13.6 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Aminotran_1_2 PF00155.21 ORX99843.1 - 1.4e-87 294.2 0.0 1.6e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acyltransferase PF01553.21 ORX99844.1 - 2.8e-10 39.9 0.0 6.3e-09 35.6 0.0 2.6 1 1 0 1 1 1 1 Acyltransferase DUF4220 PF13968.6 ORX99844.1 - 0.0086 15.5 0.8 0.013 14.9 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) PGAP1 PF07819.13 ORX99845.1 - 5.1e-88 294.7 0.0 8.1e-88 294.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORX99845.1 - 6.8e-05 23.6 0.1 0.0011 19.6 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 ORX99845.1 - 0.002 17.6 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ORX99845.1 - 0.0044 16.9 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 ORX99845.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORX99845.1 - 0.088 12.4 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold ESCRT-II PF05871.12 ORX99846.1 - 2.6e-50 170.3 0.7 3.4e-50 169.9 0.7 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Spc7 PF08317.11 ORX99847.1 - 0.00016 20.7 12.6 0.0002 20.4 12.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein KASH_CCD PF14662.6 ORX99847.1 - 0.0071 16.2 15.1 0.0092 15.8 15.1 1.0 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Flu_M1 PF00598.19 ORX99847.1 - 0.0074 15.8 0.7 0.0098 15.4 0.7 1.2 1 0 0 1 1 1 1 Influenza Matrix protein (M1) CorA PF01544.18 ORX99847.1 - 0.023 14.0 3.8 0.03 13.6 3.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 ORX99847.1 - 0.036 13.7 6.6 0.039 13.5 6.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 ORX99847.1 - 0.038 12.6 8.3 0.049 12.2 8.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A EzrA PF06160.12 ORX99847.1 - 0.04 12.1 12.4 0.051 11.7 12.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 ORX99847.1 - 0.042 14.4 7.5 0.82 10.3 1.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SesA PF17107.5 ORX99847.1 - 0.054 13.7 6.5 0.083 13.1 5.4 1.7 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF745 PF05335.13 ORX99847.1 - 0.06 13.1 7.5 0.077 12.7 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) HOOK PF05622.12 ORX99847.1 - 0.068 11.3 14.0 0.084 11.0 14.0 1.0 1 0 0 1 1 1 0 HOOK protein DUF4250 PF14056.6 ORX99847.1 - 0.077 13.0 1.1 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) HAMP PF00672.25 ORX99847.1 - 0.098 13.0 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 HAMP domain Seryl_tRNA_N PF02403.22 ORX99847.1 - 0.12 12.6 13.6 2.4 8.5 8.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GPO PF05929.11 ORX99847.1 - 0.17 11.5 6.3 0.21 11.2 6.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 ORX99847.1 - 0.23 11.7 8.0 0.33 11.1 8.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 ORX99847.1 - 0.43 10.6 19.9 1 9.4 20.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 ORX99847.1 - 0.77 9.8 8.5 0.82 9.7 7.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 ORX99847.1 - 1 9.0 15.2 6.8 6.3 15.2 2.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 ORX99847.1 - 1.1 9.6 11.6 0.41 11.0 4.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC-167 PF15188.6 ORX99847.1 - 2 8.8 13.1 0.24 11.8 7.3 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Atg14 PF10186.9 ORX99847.1 - 3 6.8 11.2 3.8 6.5 11.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 ORX99847.1 - 3 7.1 12.6 7 5.9 12.5 1.6 1 1 1 2 2 2 0 FAM76 protein MPS2 PF17060.5 ORX99847.1 - 3.3 6.9 13.6 14 4.8 13.5 1.8 1 1 0 1 1 1 0 Monopolar spindle protein 2 CENP-H PF05837.12 ORX99847.1 - 4.9 7.6 15.5 2.9 8.3 4.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 ORX99847.1 - 5.5 7.4 20.5 6.1 7.3 5.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Cauli_AT PF03233.13 ORX99847.1 - 6.1 6.7 9.5 8.4 6.3 7.4 1.9 1 1 1 2 2 2 0 Aphid transmission protein KIP1 PF07765.12 ORX99847.1 - 7.1 6.8 9.1 10 6.3 6.2 2.2 1 1 1 2 2 2 0 KIP1-like protein TMPIT PF07851.13 ORX99847.1 - 7.7 5.7 13.5 16 4.6 13.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 ORX99847.1 - 9.1 6.3 18.7 19 5.3 18.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GLTSCR1 PF15249.6 ORX99847.1 - 9.2 6.8 10.5 2.9 8.4 2.2 2.6 1 1 2 3 3 3 0 Conserved region of unknown function on GLTSCR protein RabGAP-TBC PF00566.18 ORX99848.1 - 1.5e-36 126.1 0.9 1.9e-36 125.8 0.9 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_S3Ae PF01015.18 ORX99849.1 - 4.4e-49 166.8 0.7 5.5e-49 166.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 ORX99849.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Myb_DNA-bind_4 PF13837.6 ORX99850.1 - 2.5e-19 69.4 3.2 2.5e-19 69.4 3.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORX99850.1 - 1.6e-08 34.6 1.4 1.6e-08 34.6 1.4 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORX99850.1 - 3.4e-07 30.4 3.1 3.4e-07 30.4 3.1 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORX99850.1 - 0.00081 19.7 1.3 0.00081 19.7 1.3 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 ORX99850.1 - 0.002 18.2 4.1 0.002 18.2 4.1 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORX99850.1 - 0.011 16.7 3.3 0.011 16.7 3.3 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SopE_GEF PF07487.13 ORX99850.1 - 0.15 12.2 1.1 0.53 10.4 0.3 1.9 2 0 0 2 2 2 0 SopE GEF domain Ion_trans PF00520.31 ORX99851.1 - 0.0036 16.6 5.5 0.0046 16.2 5.5 1.1 1 0 0 1 1 1 1 Ion transport protein CitMHS PF03600.16 ORX99851.1 - 0.051 12.8 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter Ribosomal_L22 PF00237.19 ORX99852.1 - 4.7e-25 87.8 0.1 6e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Chromo PF00385.24 ORX99853.1 - 3.1e-09 36.6 3.4 3.1e-09 36.6 3.4 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1157 PF06636.11 ORX99853.1 - 0.22 10.3 0.1 0.35 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) FAM176 PF14851.6 ORX99853.1 - 9.3 5.9 9.6 11 5.6 4.8 2.4 2 0 0 2 2 2 0 FAM176 family ThiF PF00899.21 ORX99854.1 - 7.1e-34 117.2 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORX99854.1 - 1.2e-05 25.6 0.5 7.4e-05 23.0 0.5 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ORX99854.1 - 0.00057 19.6 0.0 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ORX99854.1 - 0.0013 19.3 1.8 0.32 11.6 0.6 3.9 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORX99854.1 - 0.0029 17.2 0.4 0.0054 16.4 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORX99854.1 - 0.0065 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORX99854.1 - 0.014 15.9 0.9 0.67 10.4 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ORX99854.1 - 0.017 14.3 0.4 0.1 11.8 0.2 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORX99854.1 - 0.03 14.4 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 ORX99854.1 - 0.031 13.4 0.1 0.054 12.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 ORX99854.1 - 0.032 13.6 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Stealth_CR3 PF17102.5 ORX99854.1 - 0.034 14.1 0.0 8.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 TrkA_N PF02254.18 ORX99854.1 - 0.036 14.3 0.2 0.1 12.9 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 ORX99854.1 - 0.11 12.4 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORX99854.1 - 0.13 12.3 0.7 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PRIMA1 PF16101.5 ORX99855.1 - 0.0073 16.3 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Proline-rich membrane anchor 1 PhoR PF11808.8 ORX99855.1 - 0.023 15.1 0.0 0.087 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR SKG6 PF08693.10 ORX99855.1 - 0.039 13.4 2.5 0.039 13.4 2.5 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 ORX99855.1 - 0.064 13.0 1.7 0.069 12.9 0.1 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 VSP PF03302.13 ORX99855.1 - 0.13 11.1 2.9 0.17 10.7 2.9 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Inhibitor_Mig-6 PF11555.8 ORX99856.1 - 0.25 11.5 4.5 0.47 10.6 4.5 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 NMN_transporter PF04973.12 ORX99857.1 - 0.043 13.8 10.3 0.06 13.3 10.3 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Pkr1 PF08636.10 ORX99857.1 - 0.16 12.2 3.9 0.26 11.4 0.2 2.4 2 0 0 2 2 2 0 ER protein Pkr1 Tetraspanin PF00335.20 ORX99857.1 - 0.26 11.0 13.8 0.71 9.5 13.8 1.8 1 1 0 1 1 1 0 Tetraspanin family CD20 PF04103.15 ORX99857.1 - 0.71 9.9 11.2 0.36 10.9 8.7 1.7 2 0 0 2 2 2 0 CD20-like family Collectrin PF16959.5 ORX99857.1 - 0.88 9.3 3.4 0.95 9.2 0.9 2.0 2 0 0 2 2 2 0 Renal amino acid transporter DUF2981 PF11200.8 ORX99857.1 - 0.91 9.2 5.8 2.8 7.6 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4728 PF15860.5 ORX99857.1 - 1 10.1 11.3 0.051 14.3 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) DUF983 PF06170.12 ORX99857.1 - 2.1 8.8 7.3 6.2 7.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF2070 PF09843.9 ORX99857.1 - 2.6 6.2 6.5 3.2 5.9 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ldh_1_N PF00056.23 ORX99858.1 - 2.2e-36 125.1 0.3 3.3e-36 124.5 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORX99858.1 - 9.1e-19 68.0 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DAO PF01266.24 ORX99858.1 - 4.3e-05 23.3 0.1 0.00016 21.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORX99858.1 - 0.0039 16.5 0.1 0.0055 16.0 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PEP_hydrolase PF09370.10 ORX99858.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like NAD_binding_7 PF13241.6 ORX99858.1 - 0.14 12.6 0.2 0.54 10.7 0.1 2.0 2 1 1 3 3 3 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ORX99858.1 - 0.39 10.3 1.7 7.9 6.0 1.7 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_2 PF13347.6 ORX99859.1 - 1.9e-08 33.3 0.9 1.9e-08 33.3 0.9 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 ORX99859.1 - 1.6e-07 30.7 0.6 3.6e-07 29.5 0.6 1.6 1 0 0 1 1 1 1 PUCC protein DUF5336 PF17270.2 ORX99859.1 - 0.65 9.6 0.0 0.65 9.6 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5336) BioY PF02632.14 ORX99859.1 - 5.1 7.2 14.1 0.29 11.2 3.1 3.4 3 1 0 3 3 3 0 BioY family Ribosomal_L37e PF01907.19 ORX99860.1 - 1.1e-27 95.9 12.0 1.7e-27 95.3 12.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORX99860.1 - 0.011 15.7 1.6 0.017 15.2 1.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ORX99860.1 - 0.034 14.2 0.7 0.048 13.7 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SelR PF01641.18 ORX99860.1 - 0.039 14.0 1.2 0.049 13.7 1.1 1.3 1 1 0 1 1 1 0 SelR domain zf-RING_5 PF14634.6 ORX99860.1 - 0.072 13.1 3.6 0.11 12.5 3.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 ORX99860.1 - 0.31 10.5 3.7 2.3 7.7 3.7 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 ORX99860.1 - 0.59 9.7 4.3 2.3 7.8 0.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon HPP PF04982.13 ORX99861.1 - 3e-29 101.7 4.8 4e-29 101.3 4.8 1.2 1 0 0 1 1 1 1 HPP family DUF2070 PF09843.9 ORX99861.1 - 2.4 6.3 8.9 3.2 6.0 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 ORX99862.1 - 1.7e-06 28.0 10.3 1.7e-06 28.0 10.3 2.8 1 1 1 2 2 2 1 Tetraspanin family Vma12 PF11712.8 ORX99862.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.7 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Arrestin_C PF02752.22 ORX99863.1 - 1.4e-10 41.7 5.4 1.8e-10 41.4 2.2 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORX99863.1 - 1.3e-07 31.7 0.2 9.7e-07 28.9 0.1 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 ORX99863.1 - 0.0011 18.1 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 ORX99864.1 - 5.5e-07 29.7 0.1 9.7e-06 25.7 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORX99864.1 - 4.6e-06 27.1 0.5 6.6e-05 23.4 0.5 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORX99864.1 - 0.007 16.1 0.0 0.026 14.2 0.0 1.9 1 1 0 1 1 1 1 Arrestin_N terminal like Aa_trans PF01490.18 ORX99865.1 - 3.4e-49 167.7 23.8 5.4e-49 167.0 23.8 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sarcolipin PF05366.11 ORX99865.1 - 0.092 12.5 0.5 0.37 10.5 0.5 2.1 1 0 0 1 1 1 0 Sarcolipin ERGIC_N PF13850.6 ORX99865.1 - 0.31 11.4 1.2 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF697 PF05128.12 ORX99867.1 - 0.71 9.6 4.7 1.3 8.7 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) Glyco_hydro_18 PF00704.28 ORX99868.1 - 1.3e-13 51.4 3.2 1.5e-13 51.1 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Band_7 PF01145.25 ORX99869.1 - 6.9e-27 94.6 0.6 9.7e-27 94.1 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORX99869.1 - 0.036 13.8 0.1 0.071 12.8 0.1 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORX99869.1 - 0.06 12.9 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 CHAP PF05257.16 ORX99901.1 - 3.6e-07 30.7 4.1 8.7e-07 29.4 4.1 1.8 1 1 0 1 1 1 1 CHAP domain SOXp PF12336.8 ORX99901.1 - 0.035 15.2 1.7 0.036 15.1 0.4 1.7 1 1 1 2 2 2 0 SOX transcription factor CHAP PF05257.16 ORX99902.1 - 2.1e-11 44.2 3.4 3.6e-11 43.5 3.4 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX99903.1 - 1.9e-11 44.4 3.4 2.9e-11 43.8 3.4 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX99904.1 - 1e-10 42.0 1.5 1e-10 42.0 1.5 2.1 2 0 0 2 2 2 1 CHAP domain Vps39_2 PF10367.9 ORX99906.1 - 5.8e-33 113.6 0.6 2e-32 111.9 0.4 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ORX99906.1 - 9.8e-33 112.7 7.2 3.6e-30 104.4 0.0 4.9 3 1 2 5 5 5 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 ORX99906.1 - 5.6e-23 81.9 0.0 1.1e-22 80.9 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 ORX99906.1 - 3e-21 75.8 11.4 6.5e-17 61.7 0.7 4.2 4 0 0 4 4 4 2 Region in Clathrin and VPS Viral_DNA_bi PF02236.17 ORX99906.1 - 0.0022 18.1 0.0 0.0071 16.5 0.0 1.9 2 0 0 2 2 2 1 Viral DNA-binding protein, all alpha domain TPR_7 PF13176.6 ORX99906.1 - 0.016 15.2 0.5 9.3 6.5 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORX99906.1 - 0.061 13.8 2.2 0.27 11.8 0.2 3.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX99906.1 - 0.17 12.2 5.7 1.3 9.4 0.2 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 ORX99906.1 - 0.27 11.6 2.3 91 3.6 0.0 4.7 6 0 0 6 6 6 0 PPR repeat Pkinase PF00069.25 ORX99907.1 - 8.1e-71 238.5 0.0 9.9e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORX99907.1 - 1.5e-46 158.8 0.0 1.9e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORX99907.1 - 8.7e-06 24.8 0.3 1.1e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORX99907.1 - 9.2e-06 25.2 0.0 3.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORX99907.1 - 0.0016 17.8 0.3 0.0027 17.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORX99907.1 - 0.0038 16.9 0.1 0.11 12.2 0.0 2.2 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORX99907.1 - 0.0058 16.2 0.3 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 ORX99907.1 - 0.006 15.6 0.1 0.0092 15.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 ORX99907.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 ORX99907.1 - 0.072 13.0 0.1 0.23 11.3 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family S-AdoMet_synt_C PF02773.16 ORX99908.1 - 1.5e-68 229.1 0.1 3.3e-68 228.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORX99908.1 - 7.8e-47 158.5 0.0 1.5e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORX99908.1 - 1.6e-45 153.8 0.1 3.3e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORX99908.1 - 0.024 13.4 0.4 0.078 11.8 0.1 1.8 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) S-AdoMet_synt_C PF02773.16 ORX99909.1 - 1.5e-68 229.1 0.1 3.3e-68 228.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORX99909.1 - 7.8e-47 158.5 0.0 1.5e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORX99909.1 - 1.6e-45 153.8 0.1 3.3e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORX99909.1 - 0.022 13.5 0.3 0.074 11.8 0.1 1.8 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) CASP_C PF08172.12 ORX99910.1 - 1.8e-59 201.1 15.1 1.8e-59 201.1 15.1 5.5 2 2 1 4 4 3 1 CASP C terminal Golgin_A5 PF09787.9 ORX99910.1 - 6.6e-05 22.5 62.1 0.0005 19.6 10.2 4.0 1 1 2 3 3 3 2 Golgin subfamily A member 5 ADIP PF11559.8 ORX99910.1 - 0.00035 20.7 13.1 0.0075 16.4 10.9 5.4 3 1 1 5 5 5 2 Afadin- and alpha -actinin-Binding PKcGMP_CC PF16808.5 ORX99910.1 - 0.00092 19.0 1.0 0.00092 19.0 1.0 5.9 6 0 0 6 6 6 2 Coiled-coil N-terminus of cGMP-dependent protein kinase PRKG1_interact PF15898.5 ORX99910.1 - 0.013 16.4 8.6 0.013 16.4 8.6 5.6 2 2 3 5 5 5 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 ORX99910.1 - 0.058 12.9 64.4 0.27 10.7 8.2 4.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 ORX99910.1 - 0.72 10.1 60.9 1.8 8.8 9.1 6.5 3 1 3 6 6 6 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ORX99910.1 - 0.8 10.1 60.5 0.36 11.2 26.6 3.4 1 1 1 2 2 2 0 Fez1 Filament PF00038.21 ORX99910.1 - 1.1 8.8 58.5 0.067 12.8 13.5 4.4 2 1 2 4 4 4 0 Intermediate filament protein IFT46_B_C PF12317.8 ORX99910.1 - 2.6 7.7 15.2 13 5.5 0.5 3.3 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal MscS_porin PF12795.7 ORX99910.1 - 3.2 7.2 54.1 0.23 11.0 7.6 4.6 2 1 1 4 4 4 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 ORX99910.1 - 4 6.7 42.2 2.2 7.5 17.4 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 ORX99910.1 - 8.2 6.5 69.7 1.2 9.1 0.2 5.7 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Septin PF00735.18 ORX99911.1 - 3.8e-110 367.6 0.0 4.6e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORX99911.1 - 6.9e-06 26.1 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORX99911.1 - 2.5e-05 24.4 0.0 0.1 12.7 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 ORX99911.1 - 0.00099 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 ORX99911.1 - 0.0031 17.4 0.1 0.039 13.9 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORX99911.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Aldo_ket_red PF00248.21 ORX99912.1 - 1e-50 172.6 0.3 5.7e-50 170.2 0.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family TetR_C_5 PF08360.11 ORX99912.1 - 0.029 14.6 0.1 0.061 13.5 0.1 1.6 1 0 0 1 1 1 0 QacR-like protein, C-terminal region DUF3126 PF11324.8 ORX99912.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Cyt-b5 PF00173.28 ORX99913.1 - 2.6e-23 81.9 0.2 4.5e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORX99913.1 - 4.7e-14 52.9 16.4 4.7e-14 52.9 16.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Multi_Drug_Res PF00893.19 ORX99913.1 - 0.6 10.8 3.9 3.7 8.3 0.7 2.3 2 0 0 2 2 2 0 Small Multidrug Resistance protein Ribosomal_L39 PF00832.20 ORX99914.1 - 1.3e-22 79.2 10.8 1.7e-22 78.7 10.8 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein PALB2_WD40 PF16756.5 ORX99915.1 - 0.0071 15.3 1.1 1.3 7.9 0.0 2.6 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain ANAPC4_WD40 PF12894.7 ORX99915.1 - 0.055 13.8 0.0 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Trm112p PF03966.16 ORX99916.1 - 1.6e-20 73.4 0.1 2.1e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein zf-BED PF02892.15 ORX99916.1 - 0.061 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger ADK_lid PF05191.14 ORX99916.1 - 0.092 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid LAMTOR PF15454.6 ORX99917.1 - 1.6e-09 38.2 1.6 3e-09 37.4 1.6 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator YqgF PF14639.6 ORX99917.1 - 0.1 12.3 0.5 0.16 11.7 0.1 1.5 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 AhpC-TSA PF00578.21 ORX99918.1 - 3.4e-37 127.1 0.0 4.3e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORX99918.1 - 1.9e-16 60.1 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORX99918.1 - 5.3e-11 42.2 0.1 8.8e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 ORX99918.1 - 0.0047 16.8 0.2 0.0096 15.8 0.2 1.4 1 0 0 1 1 1 1 SCO1/SenC Chitin_synth_2 PF03142.15 ORX99919.1 - 1.1e-274 912.0 0.3 1.6e-274 911.4 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORX99919.1 - 1.2e-14 54.8 0.1 2.9e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORX99919.1 - 3.9e-12 46.5 2.8 3.9e-12 46.5 2.8 2.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORX99919.1 - 3e-05 23.9 0.0 0.0098 15.7 0.0 2.9 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORX99919.1 - 0.00049 19.6 0.2 0.092 12.2 0.1 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 21 DUF1828 PF08861.10 ORX99919.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF4824 PF16106.5 ORX99919.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) Pribosyltran PF00156.27 ORX99920.1 - 1.8e-23 82.8 0.0 2.3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORX99920.1 - 0.0094 15.4 0.0 0.012 15.1 0.0 1.3 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 ORX99920.1 - 0.065 12.7 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Abhydrolase_3 PF07859.13 ORX99921.1 - 1.1e-37 130.0 0.0 5.4e-28 98.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORX99921.1 - 0.041 12.8 0.1 0.15 10.9 0.1 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase SelP_N PF04592.14 ORX99921.1 - 0.39 10.1 7.8 0.7 9.3 7.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Metallophos PF00149.28 ORX99922.1 - 3.2e-35 122.5 0.5 4.3e-35 122.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORX99922.1 - 0.0075 16.7 0.1 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORX99922.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain WD40 PF00400.32 ORX99924.1 - 2e-59 196.2 14.8 4.5e-09 36.8 0.0 7.7 8 0 0 8 8 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORX99924.1 - 3e-29 101.1 8.5 4.3e-29 100.6 8.5 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORX99924.1 - 3e-23 81.9 0.0 9.9e-05 22.6 0.0 6.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORX99924.1 - 5.2e-10 39.1 0.0 0.01 15.2 0.0 4.7 6 0 0 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 ORX99924.1 - 2.9e-09 36.4 0.2 0.21 10.5 0.0 5.1 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORX99924.1 - 5.7e-06 26.3 0.0 0.019 14.9 0.0 3.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ORX99924.1 - 1e-05 25.0 0.1 0.54 9.5 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 ORX99924.1 - 1.5e-05 24.8 0.1 13 5.9 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 ORX99924.1 - 3.4e-05 22.7 0.2 0.35 9.5 0.0 3.8 3 1 2 5 5 5 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 ORX99924.1 - 0.0022 17.7 0.8 3.3 7.5 0.0 4.6 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.16 ORX99924.1 - 0.0031 16.1 0.3 0.038 12.5 0.1 2.3 1 1 2 3 3 3 2 Cytochrome D1 heme domain CEP63 PF17045.5 ORX99924.1 - 0.023 14.6 3.9 0.036 14.0 3.9 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Peptidase_S9_N PF02897.15 ORX99924.1 - 0.03 13.1 0.0 1.1 8.0 0.0 2.8 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Spc7 PF08317.11 ORX99924.1 - 0.055 12.3 2.8 0.079 11.8 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 ORX99924.1 - 0.061 12.8 3.1 0.09 12.2 3.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5122 PF17164.4 ORX99924.1 - 0.14 12.5 0.5 68 3.9 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller DUF3450 PF11932.8 ORX99924.1 - 0.27 10.5 4.9 0.5 9.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPX2 PF06886.11 ORX99924.1 - 3.4 8.0 6.1 6 7.2 6.1 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) SRP14 PF02290.15 ORX99925.1 - 1.1e-22 80.2 0.4 1.5e-22 79.7 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Sec23_trunk PF04811.15 ORX99926.1 - 1.4e-72 244.2 0.0 2e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORX99926.1 - 1.3e-25 89.2 0.1 2.3e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORX99926.1 - 1.1e-17 64.6 0.0 2.3e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORX99926.1 - 2.7e-17 62.5 4.7 5.4e-17 61.6 4.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORX99926.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORX99926.1 - 0.00065 19.1 0.1 0.0015 17.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain ALS_ss_C PF10369.9 ORX99927.1 - 2.8e-20 72.3 0.1 3.8e-18 65.5 0.0 2.7 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 ORX99927.1 - 1.7e-14 53.2 0.1 3.6e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORX99927.1 - 6.9e-09 35.4 0.1 1.3e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 ACT domain MEIOC PF15189.6 ORX99927.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC TPP_enzyme_N PF02776.18 ORX99928.1 - 9.8e-56 188.1 0.0 1.8e-55 187.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORX99928.1 - 1.8e-51 174.0 0.0 5.2e-50 169.2 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORX99928.1 - 7.3e-37 126.2 0.2 1.7e-36 125.0 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UcrQ PF02939.16 ORX99929.1 - 3.6e-32 110.1 0.4 4.1e-32 110.0 0.4 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 ORX99929.1 - 0.051 14.0 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Pam17 PF08566.10 ORX99930.1 - 2.1e-59 200.1 0.0 2.3e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Methyltransf_11 PF08241.12 ORX99931.1 - 8.7e-16 58.4 0.0 2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORX99931.1 - 4.6e-14 52.6 0.0 7.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORX99931.1 - 1.1e-12 48.5 0.0 2.4e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORX99931.1 - 2.1e-10 41.2 0.2 4.3e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORX99931.1 - 8.6e-10 38.3 0.1 1.3e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORX99931.1 - 1.6e-06 27.9 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORX99931.1 - 0.0041 16.3 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.12 ORX99931.1 - 0.095 12.2 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase AAA PF00004.29 ORX99933.1 - 1.1e-58 197.4 0.0 6.1e-35 120.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORX99933.1 - 5.4e-15 54.9 1.1 5.5e-13 48.5 0.0 2.7 2 1 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 ORX99933.1 - 1.9e-13 51.2 0.1 6.7e-05 23.3 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORX99933.1 - 1.6e-09 38.1 2.8 0.0051 17.1 0.3 3.9 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 ORX99933.1 - 5.3e-09 36.0 0.1 0.0086 15.8 0.0 3.4 3 1 0 3 3 3 2 IstB-like ATP binding protein DUF815 PF05673.13 ORX99933.1 - 1.1e-08 34.6 0.0 2.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 ORX99933.1 - 1.1e-08 35.1 0.2 0.0082 16.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORX99933.1 - 2.9e-08 33.8 0.0 0.00014 21.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 ORX99933.1 - 2.2e-07 30.9 0.0 6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_24 PF13479.6 ORX99933.1 - 3.4e-06 26.9 0.0 0.078 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORX99933.1 - 1.1e-05 25.6 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ORX99933.1 - 1.3e-05 25.7 0.0 0.074 13.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 ORX99933.1 - 2.7e-05 23.8 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 ORX99933.1 - 3.1e-05 23.6 0.0 0.64 9.6 0.1 4.2 3 1 0 4 4 4 1 AAA domain RuvB_N PF05496.12 ORX99933.1 - 3.5e-05 23.6 0.0 0.0022 17.7 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 ORX99933.1 - 3.8e-05 23.7 0.0 0.74 9.7 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 ORX99933.1 - 6.3e-05 22.5 0.0 0.012 15.0 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORX99933.1 - 0.00014 21.6 0.1 0.42 10.3 0.0 3.1 4 0 0 4 4 3 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 ORX99933.1 - 0.00016 21.0 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 ORX99933.1 - 0.00024 21.5 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 ORX99933.1 - 0.00041 20.3 0.0 1.8 8.5 0.0 2.9 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 ORX99933.1 - 0.0005 20.4 0.0 0.46 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 ORX99933.1 - 0.0012 18.3 0.1 1.3 8.4 0.0 3.6 4 0 0 4 4 4 1 Bacterial TniB protein AAA_30 PF13604.6 ORX99933.1 - 0.0019 17.9 0.2 0.79 9.4 0.0 3.0 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 ORX99933.1 - 0.002 18.1 0.0 0.66 10.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 ORX99933.1 - 0.0021 17.7 0.0 2.9 7.7 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain ATPase PF06745.13 ORX99933.1 - 0.0023 17.3 0.0 0.13 11.5 0.0 3.0 3 0 0 3 3 3 1 KaiC AAA_2 PF07724.14 ORX99933.1 - 0.0029 17.8 0.0 0.56 10.3 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORX99933.1 - 0.0038 17.8 0.0 0.08 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORX99933.1 - 0.0041 16.4 0.0 0.02 14.1 0.0 2.0 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_3 PF07726.11 ORX99933.1 - 0.0047 16.8 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORX99933.1 - 0.0048 17.2 0.2 3.1 8.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 ORX99933.1 - 0.006 16.7 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATP_bind_1 PF03029.17 ORX99933.1 - 0.0068 16.2 0.1 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 ORX99933.1 - 0.0093 15.6 0.0 0.63 9.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 ORX99933.1 - 0.018 14.1 0.0 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain PhoH PF02562.16 ORX99933.1 - 0.023 14.1 0.0 0.31 10.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 ORX99933.1 - 0.026 14.2 0.0 0.92 9.1 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 ORX99933.1 - 0.026 14.9 0.0 6.8 7.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 ORX99933.1 - 0.034 13.8 0.0 0.74 9.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.15 ORX99933.1 - 0.085 12.8 0.0 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 ORX99933.1 - 0.098 11.8 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 ORX99933.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 mRNA_cap_enzyme PF01331.19 ORX99934.1 - 2.3e-50 171.2 0.1 2.9e-50 170.8 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORX99934.1 - 2.2e-28 99.0 0.0 5.3e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 ORX99934.1 - 1.3e-08 34.8 0.0 0.00065 19.4 0.0 2.7 2 1 1 3 3 3 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ORX99934.1 - 0.0031 17.8 0.0 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA ligase RNA_polI_A34 PF08208.11 ORX99935.1 - 0.0046 17.1 4.1 0.0057 16.8 4.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 BUD22 PF09073.10 ORX99935.1 - 0.027 13.8 8.4 0.029 13.7 8.4 1.1 1 0 0 1 1 1 0 BUD22 EBP50_C PF09007.11 ORX99935.1 - 0.059 14.4 11.4 0.1 13.6 11.4 1.4 1 0 0 1 1 1 0 EBP50, C-terminal Plasmodium_Vir PF05795.11 ORX99935.1 - 0.06 12.8 10.4 0.076 12.4 10.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Menin PF05053.13 ORX99935.1 - 0.08 11.3 9.3 0.098 11.0 9.3 1.0 1 0 0 1 1 1 0 Menin MID_MedPIWI PF18296.1 ORX99935.1 - 0.31 10.8 10.1 0.5 10.1 10.1 1.3 1 0 0 1 1 1 0 MID domain of medPIWI SPX PF03105.19 ORX99935.1 - 0.44 10.4 13.8 0.49 10.2 13.8 1.1 1 0 0 1 1 1 0 SPX domain DUF4050 PF13259.6 ORX99935.1 - 0.51 10.6 7.9 0.71 10.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Macoilin PF09726.9 ORX99935.1 - 0.51 8.8 15.8 0.57 8.7 15.8 1.0 1 0 0 1 1 1 0 Macoilin family VDE PF07137.11 ORX99935.1 - 0.68 9.4 7.2 0.93 9.0 7.2 1.2 1 0 0 1 1 1 0 VDE lipocalin domain Apt1 PF10351.9 ORX99935.1 - 0.9 8.3 12.6 1 8.1 12.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 ORX99935.1 - 0.99 8.1 5.7 1 8.0 5.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SR-25 PF10500.9 ORX99935.1 - 1.8 8.1 24.3 2.5 7.6 24.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 ORX99935.1 - 1.9 6.5 26.1 2.1 6.3 26.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ASD2 PF08687.11 ORX99935.1 - 2.2 7.8 4.2 2.7 7.5 4.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Lin-8 PF03353.15 ORX99935.1 - 2.4 7.6 5.0 2.7 7.5 5.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAP1 PF08601.10 ORX99935.1 - 2.4 7.8 21.6 2.7 7.6 21.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Presenilin PF01080.17 ORX99935.1 - 3.2 6.4 9.7 4.4 6.0 9.7 1.2 1 0 0 1 1 1 0 Presenilin CytochromB561_N PF09786.9 ORX99935.1 - 3.9 6.4 14.5 4.3 6.2 14.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Tmemb_cc2 PF10267.9 ORX99935.1 - 4.2 6.4 9.1 5.5 6.0 9.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GREB1 PF15782.5 ORX99935.1 - 5.7 3.9 14.7 6.3 3.8 14.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAP65_ASE1 PF03999.12 ORX99935.1 - 7.5 5.1 11.3 8.9 4.9 11.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Peroxin-3 PF04882.12 ORX99935.1 - 9.6 5.1 13.0 12 4.7 13.0 1.1 1 0 0 1 1 1 0 Peroxin-3 HAP1_N PF04849.13 ORX99936.1 - 3e-05 23.4 26.9 0.00015 21.1 3.4 3.5 1 1 2 3 3 3 1 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 ORX99936.1 - 0.0023 18.1 4.7 0.0023 18.1 4.7 3.2 1 1 3 4 4 4 1 Tropomyosin like Laminin_II PF06009.12 ORX99936.1 - 0.0051 16.8 2.7 0.0051 16.8 2.7 2.8 2 1 0 3 3 3 1 Laminin Domain II zf-C4H2 PF10146.9 ORX99936.1 - 0.0069 16.7 2.5 0.0069 16.7 2.5 2.7 1 1 2 3 3 3 1 Zinc finger-containing protein DUF1664 PF07889.12 ORX99936.1 - 0.0084 16.1 17.6 0.14 12.2 5.9 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) GIT_CC PF16559.5 ORX99936.1 - 0.074 12.9 11.4 0.13 12.2 0.1 3.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor OSR1_C PF12202.8 ORX99936.1 - 0.1 12.8 0.3 0.1 12.8 0.3 1.8 2 0 0 2 2 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain BLOC1_2 PF10046.9 ORX99936.1 - 0.11 12.8 13.7 1.6 9.1 2.7 3.7 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 ORX99936.1 - 0.19 11.9 9.0 0.6 10.2 0.2 3.6 4 0 0 4 4 4 0 bZIP transcription factor ZapB PF06005.12 ORX99936.1 - 0.28 11.6 23.8 0.35 11.3 0.3 4.4 3 1 1 4 4 4 0 Cell division protein ZapB Prefoldin_3 PF13758.6 ORX99936.1 - 0.48 10.5 9.1 0.042 13.9 1.5 2.7 2 1 1 3 3 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 ORX99936.1 - 1 9.4 29.7 9 6.3 18.5 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 ORX99936.1 - 1.2 9.4 7.6 0.32 11.3 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 ORX99936.1 - 1.3 9.1 28.4 0.28 11.3 13.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 ORX99936.1 - 2 8.5 19.4 1.2 9.2 0.3 2.9 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF919 PF06034.11 ORX99936.1 - 2.4 8.1 7.7 0.24 11.2 0.6 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) APG6_N PF17675.1 ORX99936.1 - 2.4 8.7 22.9 4.1 7.9 10.5 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 ORX99936.1 - 2.6 8.8 9.6 1.1 10.1 1.2 3.3 2 1 1 3 3 3 0 Occludin homology domain DUF3450 PF11932.8 ORX99936.1 - 3.9 6.7 16.7 0.15 11.4 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Es2 PF09751.9 ORX99937.1 - 5.8e-60 204.2 29.8 1e-43 150.7 18.2 3.3 2 1 1 3 3 3 2 Nuclear protein Es2 ABC_tran PF00005.27 ORX99938.1 - 4.3e-48 163.3 0.5 1.5e-24 87.0 0.0 4.5 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORX99938.1 - 2e-15 57.4 2.3 0.00015 21.6 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORX99938.1 - 7.1e-14 51.8 1.4 0.00043 19.8 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORX99938.1 - 2.3e-07 30.9 0.1 0.0072 16.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase 4HB PF17947.1 ORX99938.1 - 3.6e-07 30.2 0.1 8.6e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Four helical bundle domain AAA_23 PF13476.6 ORX99938.1 - 4.1e-07 30.7 2.8 0.1 13.1 3.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORX99938.1 - 6.1e-07 29.1 0.0 0.031 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ORX99938.1 - 1.9e-06 28.4 0.1 0.15 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 ORX99938.1 - 5e-06 26.3 0.3 1.2e-05 25.1 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 ORX99938.1 - 1e-05 25.6 0.0 0.053 13.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 ORX99938.1 - 4.3e-05 23.8 0.1 0.095 13.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORX99938.1 - 6.1e-05 23.4 0.0 0.49 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 ORX99938.1 - 0.00011 22.2 0.0 0.023 14.6 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 ORX99938.1 - 0.00012 22.3 0.0 0.35 11.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 ORX99938.1 - 0.00014 22.1 0.0 0.98 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 ORX99938.1 - 0.00017 20.7 0.3 0.13 11.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ORX99938.1 - 0.00018 22.0 0.0 0.45 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 ORX99938.1 - 0.00019 21.8 0.0 0.31 11.5 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORX99938.1 - 0.00022 21.0 0.1 0.69 9.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ORX99938.1 - 0.00049 19.9 1.4 1.5 8.5 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.6 ORX99938.1 - 0.00074 19.7 0.1 0.14 12.4 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ORX99938.1 - 0.00094 19.1 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 ORX99938.1 - 0.001 18.8 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 ORX99938.1 - 0.0013 18.8 0.3 0.18 11.9 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_27 PF13514.6 ORX99938.1 - 0.0049 16.5 0.0 4.1 6.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 ORX99938.1 - 0.0071 16.5 0.1 1.7 9.1 0.0 3.9 4 0 0 4 4 3 1 HEAT repeat ATPase_2 PF01637.18 ORX99938.1 - 0.011 15.7 0.0 0.7 9.8 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORX99938.1 - 0.013 15.0 0.1 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 ORX99938.1 - 0.016 15.0 0.2 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 ORX99938.1 - 0.023 14.7 0.0 6.5 6.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 ORX99938.1 - 0.023 14.9 0.0 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 ORX99938.1 - 0.024 14.7 0.0 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Vac14_Fab1_bd PF12755.7 ORX99938.1 - 0.029 15.0 0.0 2.5 8.8 0.0 2.8 1 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region AAA_25 PF13481.6 ORX99938.1 - 0.035 13.7 0.0 13 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 ORX99938.1 - 0.035 14.0 0.2 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 ORX99938.1 - 0.064 12.4 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 ORX99938.1 - 0.079 12.7 0.3 14 5.3 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 ORX99938.1 - 0.11 12.2 0.6 15 5.2 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase HEAT_EZ PF13513.6 ORX99938.1 - 0.12 12.9 7.1 11 6.6 0.0 5.4 6 0 0 6 6 6 0 HEAT-like repeat Dynamin_N PF00350.23 ORX99938.1 - 0.13 12.3 0.8 1 9.4 0.0 2.7 3 0 0 3 3 3 0 Dynamin family RTA1 PF04479.13 ORX99939.1 - 0.0043 16.7 3.2 0.0043 16.7 3.2 1.7 1 1 1 2 2 2 1 RTA1 like protein TauE PF01925.19 ORX99939.1 - 0.0062 16.2 7.0 0.0083 15.8 7.0 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE HisKA_7TM PF16927.5 ORX99939.1 - 0.036 14.1 6.8 0.042 13.9 6.8 1.1 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Arteri_Gl PF00951.18 ORX99939.1 - 0.054 13.3 1.8 0.12 12.1 1.8 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF4203 PF13886.6 ORX99939.1 - 0.15 11.7 11.6 0.21 11.3 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) ABC2_membrane_5 PF13346.6 ORX99939.1 - 0.59 9.7 11.5 0.038 13.5 5.9 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4345 PF14248.6 ORX99939.1 - 0.59 10.0 10.8 2.5 8.0 1.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) DUF4064 PF13273.6 ORX99939.1 - 3.4 8.0 14.6 5 7.5 10.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TssN PF17555.2 ORX99939.1 - 6.9 6.0 8.3 9.3 5.5 8.3 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN CHAP PF05257.16 ORX99940.1 - 6.5e-11 42.7 1.5 6.5e-11 42.7 1.5 1.9 2 0 0 2 2 2 1 CHAP domain Macoilin PF09726.9 ORX99940.1 - 7.5 5.0 6.4 6.7 5.1 6.4 1.0 1 0 0 1 1 1 0 Macoilin family CHAP PF05257.16 ORX99941.1 - 2.2e-11 44.2 3.4 3.6e-11 43.5 3.4 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX99942.1 - 4.6e-12 46.3 3.6 7.7e-12 45.6 3.6 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX99943.1 - 4e-11 43.3 1.7 4e-11 43.3 1.7 2.0 2 0 0 2 2 2 1 CHAP domain SOXp PF12336.8 ORX99943.1 - 1.9 9.6 7.6 1.9 9.6 5.8 2.1 1 1 0 2 2 2 0 SOX transcription factor CHAP PF05257.16 ORX99944.1 - 2.1e-11 44.2 3.4 3.6e-11 43.5 3.4 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORX99945.1 - 2.2e-11 44.2 3.4 3.6e-11 43.5 3.4 1.3 1 0 0 1 1 1 1 CHAP domain RVT_1 PF00078.27 ORX99946.1 - 1.8e-10 40.8 0.2 0.0043 16.6 0.1 3.5 2 2 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) YqzE PF14038.6 ORX99946.1 - 5.4 7.1 8.2 58 3.8 0.1 3.7 4 0 0 4 4 4 0 YqzE-like protein SNAP PF14938.6 ORX99984.1 - 7.9e-44 150.2 11.5 9.3e-44 149.9 11.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.6 ORX99984.1 - 7.7e-05 22.0 3.1 7.7e-05 22.0 3.1 2.2 1 1 1 2 2 2 1 Spatacsin C-terminus DUF2225 PF09986.9 ORX99984.1 - 0.0024 17.6 9.9 0.04 13.6 1.2 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.17 ORX99984.1 - 0.038 14.1 18.8 7.3 7.0 0.2 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORX99984.1 - 0.052 13.6 4.3 23 5.3 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 ORX99984.1 - 0.091 12.6 3.9 1.8 8.5 2.8 3.1 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_8 PF13181.6 ORX99984.1 - 0.1 12.8 13.9 0.65 10.4 1.0 4.7 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORX99984.1 - 0.14 12.5 12.8 0.13 12.6 0.9 3.7 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORX99984.1 - 0.35 10.8 0.1 0.35 10.8 0.1 5.9 7 1 0 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.12 ORX99984.1 - 0.75 10.6 4.2 30 5.5 0.3 3.6 3 0 0 3 3 3 0 Sel1 repeat TPR_10 PF13374.6 ORX99984.1 - 2 8.4 4.8 1.4 8.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Zip PF02535.22 ORX99985.1 - 6.3e-52 176.8 16.7 2.6e-51 174.8 16.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter YlaC PF10777.9 ORX99985.1 - 0.18 11.6 1.5 0.99 9.2 1.3 2.2 1 1 0 1 1 1 0 Inner membrane protein YlaC DUF3938 PF13074.6 ORX99985.1 - 3.2 8.1 6.6 15 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) DUF4514 PF14986.6 ORX99985.1 - 4 7.5 5.1 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) Zip PF02535.22 ORX99986.1 - 1.4e-53 182.2 20.1 4.5e-52 177.3 18.0 2.5 2 1 0 2 2 2 1 ZIP Zinc transporter DUF3938 PF13074.6 ORX99986.1 - 2.4 8.5 5.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) FBPase PF00316.20 ORX99988.1 - 4.9e-73 244.6 0.7 6.7e-73 244.2 0.7 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 ORX99988.1 - 0.00017 21.2 0.0 0.00052 19.6 0.0 1.7 2 0 0 2 2 2 1 Inositol monophosphatase family zf_CCCH_4 PF18345.1 ORX99988.1 - 0.052 13.6 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Zinc finger domain Ras PF00071.22 ORX99989.1 - 1.9e-50 170.6 0.0 2.3e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORX99989.1 - 4.8e-21 75.2 0.0 7.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORX99989.1 - 1e-07 31.6 0.1 1.5e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORX99989.1 - 7.1e-05 22.4 0.1 0.016 14.7 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORX99989.1 - 0.00034 20.7 0.1 0.00094 19.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORX99989.1 - 0.00042 20.2 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORX99989.1 - 0.00071 19.1 0.1 0.00085 18.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 ORX99989.1 - 0.0017 18.1 0.1 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 ORX99989.1 - 0.014 15.2 0.2 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Hpr_kinase_C PF07475.12 ORX99989.1 - 0.026 14.0 0.1 0.9 9.0 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NB-ARC PF00931.22 ORX99989.1 - 0.028 13.6 0.3 0.033 13.4 0.2 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 ORX99989.1 - 0.029 13.9 0.1 0.099 12.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 ORX99989.1 - 0.033 13.5 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 ORX99989.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 ORX99989.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.9 ORX99989.1 - 0.094 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 ORX99989.1 - 0.098 13.0 0.2 0.13 12.6 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 ORX99989.1 - 0.11 12.5 1.1 0.14 12.2 1.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 ORX99989.1 - 0.12 11.6 0.1 0.19 10.9 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RTC PF01137.21 ORX99990.1 - 1.5e-77 259.7 0.0 1.7e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ORX99990.1 - 5.9e-14 52.4 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.24 ORX99991.1 - 6.9e-18 64.7 0.0 1.4e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 PX domain XhlA PF10779.9 ORX99991.1 - 0.034 14.3 2.3 0.42 10.8 0.6 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Sigma70_r4_2 PF08281.12 ORX99991.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Ribosomal_L44 PF00935.19 ORX99992.1 - 3.9e-37 126.6 11.0 5.7e-37 126.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 PseudoU_synth_1 PF01416.20 ORX99993.1 - 5.7e-13 49.3 0.0 7.6e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase RRM_1 PF00076.22 ORX99994.1 - 4.6e-13 48.8 0.0 5.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORX99994.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif PTR2 PF00854.21 ORX99995.1 - 5e-92 308.8 0.7 8.6e-92 308.0 0.7 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORX99995.1 - 1.5e-13 50.4 7.7 1.5e-13 50.4 7.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF389 PF04087.14 ORX99995.1 - 0.0065 16.5 2.5 0.0065 16.5 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF389) MNHE PF01899.16 ORX99995.1 - 1.7 8.4 5.4 0.82 9.4 0.1 2.8 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit DUF4191 PF13829.6 ORX99995.1 - 7.3 5.9 6.6 26 4.1 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4191) DUF1275 PF06912.11 ORX99995.1 - 7.8 6.4 12.3 1.5 8.7 0.2 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1275) PTR2 PF00854.21 ORX99996.1 - 6.7e-95 318.2 5.1 9.4e-95 317.7 5.1 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORX99996.1 - 2.1e-12 46.6 18.2 8.5e-12 44.6 13.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peroxin-13_N PF04088.13 ORX99997.1 - 3.2e-43 147.5 0.2 5e-43 146.8 0.2 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 ORX99997.1 - 1.9e-13 49.8 0.0 3.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORX99997.1 - 1.9e-12 46.8 0.0 5.3e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORX99997.1 - 2.1e-12 46.5 0.0 2.1e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain MFS_1 PF07690.16 ORX99998.1 - 1.9e-17 63.2 27.1 2.6e-17 62.8 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORX99998.1 - 8.7e-14 51.5 9.3 8.7e-14 51.5 9.3 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORX99998.1 - 6.7e-05 21.9 0.6 0.03 13.2 6.0 2.1 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORX99998.1 - 0.021 13.9 10.7 0.049 12.6 8.9 2.4 2 1 1 3 3 3 0 PUCC protein DctQ PF04290.12 ORX99998.1 - 0.44 10.5 0.0 0.44 10.5 0.0 4.6 3 2 1 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component PTR2 PF00854.21 ORX99999.1 - 6.3e-94 315.0 4.5 1e-93 314.3 4.5 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORX99999.1 - 8.8e-12 44.6 11.9 8.8e-12 44.6 11.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 ORY00039.1 - 1.8e-93 313.5 2.4 2.8e-93 312.9 2.4 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY00039.1 - 5.7e-13 48.5 12.1 5.7e-13 48.5 12.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Frag1 PF10277.9 ORY00040.1 - 1.2e-34 119.8 11.7 1.2e-34 119.8 11.7 3.0 2 1 1 3 3 3 1 Frag1/DRAM/Sfk1 family Glyco_hydro_18 PF00704.28 ORY00041.1 - 5.6e-63 213.5 0.0 6.6e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 ORY00041.1 - 0.082 12.2 0.1 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 PP2C PF00481.21 ORY00042.1 - 2.5e-43 148.6 0.0 3.5e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY00042.1 - 0.00011 21.9 0.0 0.0004 20.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DEAD PF00270.29 ORY00043.1 - 1.3e-48 165.1 0.0 3.7e-48 163.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY00043.1 - 1.6e-33 115.4 0.0 4.1e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ORY00043.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ORY00043.1 - 0.025 14.6 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY00043.1 - 0.13 11.0 0.0 0.57 8.9 0.0 1.9 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Acetyltransf_1 PF00583.25 ORY00044.1 - 4e-14 52.9 0.1 6.2e-14 52.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY00044.1 - 1.4e-07 31.5 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY00044.1 - 3.1e-07 30.7 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY00044.1 - 0.0056 16.6 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Ets PF00178.22 ORY00044.1 - 1.1 9.8 4.5 8.3 7.0 0.8 2.8 2 1 0 2 2 2 0 Ets-domain CN_hydrolase PF00795.22 ORY00045.1 - 2e-64 217.5 0.1 2.3e-64 217.3 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1056 PF06341.11 ORY00046.1 - 0.4 11.0 7.1 5.7 7.3 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1056) Acetyltransf_2 PF00797.17 ORY00047.1 - 3e-56 190.9 0.0 4.1e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase DUF4562 PF15123.6 ORY00047.1 - 0.15 12.0 0.1 1.6 8.7 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4562) MFS_1 PF07690.16 ORY00048.1 - 2.4e-26 92.5 23.5 3.4e-26 92.0 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY00052.1 - 1.5e-101 340.5 28.4 1.8e-101 340.3 28.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY00052.1 - 7.8e-21 74.4 53.1 3e-18 65.9 27.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 ORY00053.1 - 7.7e-27 94.4 0.2 1.2e-26 93.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY00053.1 - 5e-21 75.4 0.0 7.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY00053.1 - 4.3e-08 32.9 0.9 2.7e-05 23.7 0.5 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORY00053.1 - 6.6e-06 26.4 0.4 6.6e-06 26.4 0.4 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ORY00053.1 - 0.0049 16.3 0.3 0.01 15.3 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ORY00053.1 - 0.022 14.2 0.6 0.7 9.2 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ORY00053.1 - 0.032 14.3 0.2 0.18 11.9 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 ORY00054.1 - 1.5e-101 340.5 28.4 1.8e-101 340.3 28.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY00054.1 - 7.8e-21 74.4 53.1 3e-18 65.9 27.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_2 PF07883.11 ORY00055.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 ORY00055.1 - 0.033 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin HAMP PF00672.25 ORY00056.1 - 1.2e-40 137.6 7.7 1e-05 25.8 0.0 8.4 8 0 0 8 8 8 7 HAMP domain HATPase_c PF02518.26 ORY00056.1 - 2.2e-31 108.6 0.0 1.2e-30 106.3 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY00056.1 - 1.6e-28 99.1 0.9 3.6e-26 91.5 0.5 3.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORY00056.1 - 7.1e-17 61.2 0.3 4.7e-16 58.6 0.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.10 ORY00056.1 - 0.0002 21.8 0.4 10 6.7 0.1 6.1 6 1 0 6 6 6 1 Domain of unknown function (DUF1843) Laminin_II PF06009.12 ORY00056.1 - 0.0011 19.0 26.6 0.3 11.1 1.7 6.4 7 0 0 7 7 7 3 Laminin Domain II GLE1 PF07817.13 ORY00056.1 - 0.0025 17.0 1.5 6.8 5.8 0.0 4.2 2 2 2 4 4 4 1 GLE1-like protein DUF3829 PF12889.7 ORY00056.1 - 0.0052 16.3 2.7 4.7 6.6 0.0 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF3829) Abhydrolase_8 PF06259.12 ORY00056.1 - 0.011 15.3 14.7 0.13 11.9 0.3 4.9 5 1 0 5 5 5 0 Alpha/beta hydrolase Thiamine_BP PF01910.17 ORY00056.1 - 0.063 13.2 7.3 0.29 11.1 0.2 4.2 2 2 3 5 5 5 0 Thiamine-binding protein DUF5344 PF17279.2 ORY00056.1 - 1 10.0 7.9 14 6.3 1.5 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5344) CENP-F_leu_zip PF10473.9 ORY00056.1 - 1.4 8.9 6.5 73 3.4 0.0 4.9 5 0 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Formin_GBD_N PF18382.1 ORY00056.1 - 3.2 8.3 6.0 12 6.4 0.1 3.9 5 0 0 5 5 5 0 Formin N-terminal GTPase-binding domain MFS_1 PF07690.16 ORY00057.1 - 6.5e-16 58.2 31.7 6.5e-16 58.2 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY00057.1 - 1.6e-10 41.0 9.5 1.6e-10 41.0 9.5 2.0 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ribosomal_L37ae PF01780.19 ORY00058.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORY00058.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORY00058.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORY00058.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORY00058.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain DUF4203 PF13886.6 ORY00059.1 - 2.7e-38 131.7 35.9 4.6e-38 130.9 34.8 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4203) DUF4538 PF15061.6 ORY00059.1 - 7.6 6.3 5.7 1.9 8.3 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) IlvN PF07991.12 ORY00060.1 - 3.6e-45 153.5 0.0 5.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORY00060.1 - 1.9e-42 145.0 0.2 3.1e-42 144.3 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 ORY00060.1 - 0.00022 21.4 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY00060.1 - 0.062 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORY00060.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 ORY00061.1 - 3.8e-45 153.4 0.0 6.2e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORY00061.1 - 2e-42 144.9 0.2 3.3e-42 144.2 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 ORY00061.1 - 0.00019 21.6 0.0 0.00056 20.1 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY00061.1 - 0.063 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORY00061.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Chs7 PF12271.8 ORY00062.1 - 1.1e-91 307.2 16.1 1.2e-91 307.0 16.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Guanylate_kin PF00625.21 ORY00063.1 - 8.4e-67 224.4 0.0 9.6e-67 224.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ORY00063.1 - 2.2e-08 34.7 0.2 5.8e-08 33.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY00063.1 - 7.4e-06 26.2 0.0 0.0001 22.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY00063.1 - 0.00017 21.9 0.0 0.00056 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY00063.1 - 0.00019 22.0 0.0 0.0005 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY00063.1 - 0.00029 20.0 0.0 0.00056 19.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORY00063.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 ORY00063.1 - 0.0018 18.2 0.0 0.0092 15.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 ORY00063.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY00063.1 - 0.0039 17.7 0.0 0.0069 16.9 0.0 1.4 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 ORY00063.1 - 0.0053 16.1 0.0 0.024 13.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 ORY00063.1 - 0.0065 16.4 0.1 0.012 15.5 0.1 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORY00063.1 - 0.0084 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 ORY00063.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY00063.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY00063.1 - 0.016 14.5 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 ORY00063.1 - 0.016 15.4 0.1 0.042 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 ORY00063.1 - 0.019 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 ORY00063.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 ORY00063.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_17 PF13207.6 ORY00063.1 - 0.04 14.3 0.3 0.28 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 ORY00063.1 - 0.048 13.5 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 ORY00063.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 ORY00063.1 - 0.054 12.7 0.0 0.096 11.9 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 ORY00063.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORY00063.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Orthopox_A43R PF06517.11 ORY00063.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 2 0 0 2 2 1 0 Orthopoxvirus A43R protein CbiA PF01656.23 ORY00063.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 ORY00063.1 - 0.11 12.1 0.1 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY00063.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain WGG PF10273.9 ORY00064.1 - 3.8e-28 98.0 0.8 3.8e-28 98.0 0.8 1.4 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 rOmpB PF12334.8 ORY00064.1 - 0.052 13.0 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Lyase_8_N PF08124.11 ORY00065.1 - 0.043 12.7 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Mito_carr PF00153.27 ORY00067.1 - 1.1e-61 204.7 2.2 3.2e-21 75.0 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Spc29 PF17082.5 ORY00068.1 - 0.0052 16.7 7.7 0.0085 16.0 7.7 1.4 1 1 0 1 1 1 1 Spindle Pole Component 29 Csm1_N PF18504.1 ORY00068.1 - 0.01 16.2 1.6 0.01 16.2 1.6 2.9 2 1 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 ORY00068.1 - 0.069 13.6 12.7 0.13 12.7 5.2 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 ORY00068.1 - 0.11 12.3 12.4 0.064 13.1 3.4 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 ORY00068.1 - 1.1 9.9 12.4 4 8.1 0.3 3.2 2 1 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.8 ORY00068.1 - 1.5 8.9 18.7 0.65 10.0 1.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 ORY00068.1 - 2.6 8.6 14.4 3.3 8.2 6.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 ORY00068.1 - 5.5 7.2 17.5 1.7 8.9 10.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 AMP-binding PF00501.28 ORY00069.1 - 7.8e-88 294.9 0.0 9.7e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY00069.1 - 1.3e-15 58.1 0.0 6.7e-14 52.6 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BP28CT PF08146.12 ORY00070.1 - 1.4e-44 151.7 9.6 4.7e-44 150.0 7.1 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain NPH3 PF03000.14 ORY00070.1 - 0.028 14.1 2.6 0.2 11.2 0.2 3.2 3 0 0 3 3 3 0 NPH3 family DDE_Tnp_IS66 PF03050.14 ORY00070.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Transposase IS66 family MyTH4 PF00784.17 ORY00070.1 - 0.24 11.9 1.5 35 4.9 0.0 4.0 3 1 0 3 3 3 0 MyTH4 domain Ank_2 PF12796.7 ORY00071.1 - 5.2e-06 27.0 0.1 9.6e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY00071.1 - 1e-05 25.8 1.5 1.6e-05 25.2 0.3 2.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORY00071.1 - 0.00024 21.6 0.0 0.076 13.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY00071.1 - 0.00043 20.5 0.2 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 ORY00071.1 - 0.00051 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Glyco_hydro_20 PF00728.22 ORY00072.1 - 1.5e-96 323.9 2.0 2.2e-96 323.3 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00072.1 - 3.7e-19 69.7 0.0 7.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY00072.1 - 0.011 16.5 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY00073.1 - 9.8e-69 232.4 9.2 3.4e-43 148.4 2.9 3.3 2 1 1 3 3 3 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00073.1 - 1.7e-21 77.3 0.0 4.2e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY00073.1 - 0.01 16.6 0.0 0.021 15.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY00074.1 - 9.8e-97 324.5 1.5 1.2e-96 324.2 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00074.1 - 5.1e-20 72.5 0.0 1.8e-19 70.8 0.0 1.9 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY00074.1 - 0.00088 20.0 0.0 0.002 18.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY00075.1 - 6.4e-104 348.1 3.4 3.3e-96 322.8 1.5 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00075.1 - 8.8e-40 136.5 0.0 9.3e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY00075.1 - 7.8e-07 29.9 0.0 0.0081 16.9 0.0 2.9 2 1 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_59M PF17387.2 ORY00075.1 - 0.0023 18.1 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 59 central domain Spore-coat_CotD PF11122.8 ORY00075.1 - 0.2 12.5 1.8 35 5.3 0.0 3.1 3 0 0 3 3 3 0 Inner spore coat protein D Glyco_hydro_20 PF00728.22 ORY00076.1 - 2.6e-170 566.5 18.4 2.1e-83 280.7 4.3 4.3 2 2 1 3 3 3 3 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00076.1 - 7.3e-46 156.2 0.0 2.2e-21 76.9 0.0 2.5 2 0 0 2 2 2 2 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY00076.1 - 4.2e-08 34.0 0.0 0.028 15.2 0.0 3.2 2 2 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_59M PF17387.2 ORY00076.1 - 0.042 14.0 0.0 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 central domain DUF3067 PF11267.8 ORY00076.1 - 0.17 12.5 0.0 49 4.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) Spore-coat_CotD PF11122.8 ORY00076.1 - 0.45 11.4 2.0 63 4.5 0.0 3.3 4 0 0 4 4 4 0 Inner spore coat protein D Glyco_hydro_20 PF00728.22 ORY00077.1 - 5.2e-183 608.3 9.4 6.4e-96 321.8 1.5 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00077.1 - 6.1e-40 137.1 0.0 2.2e-21 76.9 0.0 2.7 2 0 0 2 2 2 2 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY00077.1 - 1.2e-07 32.6 0.1 0.028 15.2 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 DUF3081 PF11280.8 ORY00077.1 - 0.0032 17.2 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3081) MDH PF02315.16 ORY00077.1 - 0.0083 16.2 0.9 4.4 7.4 0.1 2.7 2 0 0 2 2 2 2 Methanol dehydrogenase beta subunit DUF3067 PF11267.8 ORY00077.1 - 0.18 12.4 0.1 40 4.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) Glyco_hydro_20 PF00728.22 ORY00078.1 - 9.6e-97 324.5 1.5 1.2e-96 324.2 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY00078.1 - 2.5e-12 47.6 0.0 7.3e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 beta-acetyl hexosaminidase like Polysacc_deac_1 PF01522.21 ORY00079.1 - 3.2e-24 85.2 0.0 6.3e-24 84.2 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase Mito_carr PF00153.27 ORY00080.1 - 5.9e-44 147.9 1.4 1.1e-18 67.0 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Inositol_P PF00459.25 ORY00081.1 - 1.8e-69 234.3 0.0 2.1e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PX PF00787.24 ORY00082.1 - 1.4e-07 31.5 0.4 1.4e-07 31.5 0.4 2.4 2 1 0 2 2 2 1 PX domain PB1 PF00564.24 ORY00082.1 - 4.7e-07 29.7 1.0 0.001 18.9 0.1 2.7 2 0 0 2 2 2 2 PB1 domain EFTUD2 PF16004.5 ORY00082.1 - 1.4 9.5 5.8 0.28 11.8 1.5 2.1 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus PDEase_I PF00233.19 ORY00083.1 - 3.5e-71 239.7 2.1 2.3e-65 220.6 0.1 2.6 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 ORY00083.1 - 0.00046 20.3 0.0 0.00094 19.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF935 PF06074.12 ORY00083.1 - 0.13 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) F420_oxidored PF03807.17 ORY00084.1 - 4.9e-15 55.9 0.0 8.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORY00084.1 - 1.4e-07 31.0 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORY00084.1 - 0.00022 21.4 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORY00084.1 - 0.00035 20.2 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Semialdhyde_dh PF01118.24 ORY00084.1 - 0.088 13.3 0.3 0.57 10.6 0.3 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 ORY00084.1 - 0.1 12.3 0.6 1.3 8.6 0.6 2.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LVIVD PF08309.11 ORY00084.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 LVIVD repeat Shikimate_DH PF01488.20 ORY00084.1 - 0.14 12.2 0.0 0.63 10.1 0.0 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ORY00084.1 - 0.18 11.8 0.2 1.5 8.8 0.2 2.2 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tmp39 PF10271.9 ORY00085.1 - 0.065 12.2 0.1 0.074 12.0 0.1 1.0 1 0 0 1 1 1 0 Putative transmembrane protein ArAE_2 PF10334.9 ORY00086.1 - 1.6e-17 64.1 0.0 2.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY00086.1 - 3.2e-15 56.4 14.9 5.4e-15 55.6 14.9 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY00086.1 - 4.5e-12 45.3 1.4 5.5e-12 45.1 1.4 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY00086.1 - 0.023 13.5 3.6 0.031 13.1 3.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MFS_1 PF07690.16 ORY00106.1 - 9.5e-37 126.7 75.2 8e-31 107.2 39.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily IncE PF17627.2 ORY00106.1 - 0.52 10.3 3.0 15 5.6 0.3 2.8 2 1 0 2 2 2 0 Inclusion membrane protein E GATase PF00117.28 ORY00107.1 - 2.7e-18 66.4 0.2 3.7e-18 66.0 0.2 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY00107.1 - 7.1e-05 22.7 0.5 0.00018 21.3 0.5 1.8 1 1 0 1 1 1 1 Peptidase C26 Fasciclin PF02469.22 ORY00108.1 - 7.2e-55 184.7 0.0 2.8e-27 95.5 0.0 2.0 2 0 0 2 2 2 2 Fasciclin domain Topoisom_I PF01028.20 ORY00109.1 - 3.7e-98 327.4 1.7 3.7e-98 327.4 1.7 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 ORY00109.1 - 1.1e-96 322.4 1.9 1.1e-96 322.4 1.9 3.5 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 ORY00109.1 - 2.8e-35 120.1 2.2 9.3e-35 118.4 2.2 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Spa1_C PF18218.1 ORY00109.1 - 0.3 11.5 3.7 0.27 11.7 1.5 2.2 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain HAGH_C PF16123.5 ORY00110.1 - 1.5e-26 92.7 0.0 2.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY00110.1 - 4.3e-13 49.7 0.7 3.4e-12 46.8 0.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ORY00110.1 - 0.00046 20.1 0.1 0.0013 18.6 0.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ORY00110.1 - 0.00062 19.3 1.1 0.011 15.2 0.4 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RPEL PF02755.15 ORY00111.1 - 1.4e-19 69.1 5.3 2.3e-08 33.4 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat CCDC84 PF14968.6 ORY00111.1 - 0.003 17.3 0.2 0.0033 17.1 0.2 1.1 1 0 0 1 1 1 1 Coiled coil protein 84 SAA PF00277.18 ORY00112.1 - 0.32 11.5 0.8 34 5.0 0.1 2.3 2 0 0 2 2 2 0 Serum amyloid A protein Yae1_N PF09811.9 ORY00114.1 - 0.00089 18.9 0.9 0.0026 17.4 0.4 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Orthopox_C10L PF07020.11 ORY00114.1 - 6.8 7.5 9.5 1.4e+02 3.3 9.6 2.1 1 1 0 1 1 1 0 Orthopoxvirus C10L protein LRR_4 PF12799.7 ORY00115.1 - 0.00036 20.9 11.4 0.036 14.5 1.7 4.8 3 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY00115.1 - 0.0028 18.0 5.5 28 5.8 0.1 5.6 4 1 0 4 4 4 1 Leucine Rich Repeat Importin_rep PF18773.1 ORY00115.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat LRR_6 PF13516.6 ORY00115.1 - 0.16 12.1 9.0 3 8.1 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat zf-C2HC5 PF06221.13 ORY00116.1 - 4.4e-17 61.8 7.3 7e-17 61.2 7.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Med1 PF10744.9 ORY00117.1 - 3.6e-44 151.4 0.0 6.6e-44 150.6 0.0 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 CHASE7 PF17151.4 ORY00117.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain Tetraspanin PF00335.20 ORY00118.1 - 2.1e-29 102.9 2.0 2.4e-29 102.7 2.0 1.0 1 0 0 1 1 1 1 Tetraspanin family HisKA_7TM PF16927.5 ORY00118.1 - 0.03 14.4 8.0 0.078 13.0 8.0 1.8 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF4536 PF15055.6 ORY00118.1 - 0.35 11.1 1.9 15 5.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF5337 PF17272.2 ORY00118.1 - 0.66 9.8 3.4 1.1 9.2 2.4 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5337) UCR_UQCRX_QCR9 PF05365.12 ORY00118.1 - 2.3 8.2 4.4 5.2 7.1 2.2 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Snf7 PF03357.21 ORY00119.1 - 7.8e-44 149.3 16.9 9.2e-44 149.1 16.9 1.1 1 0 0 1 1 1 1 Snf7 KASH_CCD PF14662.6 ORY00119.1 - 0.12 12.2 10.0 0.061 13.2 5.3 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 ORY00119.1 - 0.14 12.5 1.8 9.7 6.7 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 ORY00119.1 - 0.33 11.4 4.8 2.6 8.6 4.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2312 PF10073.9 ORY00119.1 - 3.5 7.3 9.0 1.7 8.3 0.4 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Glyco_transf_20 PF00982.21 ORY00121.1 - 5.9e-166 552.8 0.0 8e-166 552.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY00121.1 - 8.6e-75 250.9 0.0 1.5e-74 250.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY00121.1 - 0.0032 17.2 0.0 0.7 9.6 0.0 2.6 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF883 PF05957.13 ORY00122.1 - 0.0013 19.3 1.4 0.0013 19.3 1.4 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Histidinol_dh PF00815.20 ORY00122.1 - 0.0051 15.9 1.8 0.0057 15.7 1.8 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PLC-beta_C PF08703.10 ORY00122.1 - 0.018 15.1 3.8 0.043 13.8 3.8 1.6 1 1 0 1 1 1 0 PLC-beta C terminal FIVAR PF07554.13 ORY00122.1 - 0.025 15.3 3.8 0.03 15.1 3.8 1.2 1 0 0 1 1 1 0 FIVAR domain ASPRs PF17641.2 ORY00122.1 - 0.029 14.7 0.4 0.033 14.5 0.4 1.0 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related DUF5486 PF17588.2 ORY00122.1 - 0.046 13.6 1.4 0.075 12.9 0.7 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5486) Thymidylate_kin PF02223.17 ORY00122.1 - 0.049 13.3 0.2 0.057 13.1 0.2 1.0 1 0 0 1 1 1 0 Thymidylate kinase YtxH PF12732.7 ORY00122.1 - 0.051 14.1 4.6 0.1 13.1 4.6 1.7 1 1 0 1 1 1 0 YtxH-like protein GrpE PF01025.19 ORY00122.1 - 0.27 10.9 5.9 0.35 10.5 5.9 1.1 1 0 0 1 1 1 0 GrpE AIP3 PF03915.13 ORY00123.1 - 4.3e-86 289.6 11.5 5.4e-86 289.2 11.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 MREG PF15812.5 ORY00123.1 - 0.27 11.5 2.2 0.29 11.4 0.4 1.9 2 0 0 2 2 2 0 Melanoregulin Fib_alpha PF08702.10 ORY00123.1 - 0.68 10.1 12.7 0.061 13.5 4.5 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY00123.1 - 8.9 6.9 12.0 45 4.6 0.0 5.0 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein SDF PF00375.18 ORY00124.1 - 5.1e-101 338.5 38.7 5.8e-101 338.3 38.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LapA_dom PF06305.11 ORY00124.1 - 0.0011 18.7 0.7 0.0011 18.7 0.7 3.3 4 0 0 4 4 4 1 Lipopolysaccharide assembly protein A domain Sacchrp_dh_C PF16653.5 ORY00125.1 - 1.6e-98 330.1 0.0 2.2e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY00125.1 - 8.7e-24 84.2 0.1 1.8e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY00125.1 - 8.3e-07 29.1 0.0 2.4e-06 27.6 0.0 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 ORY00125.1 - 2.9e-05 24.1 0.0 5.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY00125.1 - 0.0003 20.4 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 ORY00125.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ORY00125.1 - 0.069 13.6 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Met_synt_B12 PF02965.17 ORY00126.1 - 8e-123 409.2 0.0 1.3e-122 408.5 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 ORY00126.1 - 1.4e-78 264.4 0.0 3.1e-78 263.3 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 ORY00126.1 - 3.9e-58 197.0 2.5 6.1e-58 196.4 0.8 2.2 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 ORY00126.1 - 2.2e-23 82.5 0.0 9.1e-23 80.5 0.0 2.2 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 ORY00126.1 - 4.4e-20 71.9 0.8 4.7e-19 68.6 0.6 2.8 2 0 0 2 2 2 1 B12 binding domain MtrH PF02007.18 ORY00126.1 - 0.0073 15.4 0.1 0.019 14.1 0.1 1.7 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit CdhD PF03599.16 ORY00126.1 - 0.079 11.7 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit HIT PF01230.23 ORY00127.1 - 4.4e-25 88.3 0.0 6.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY00127.1 - 5.9e-06 26.7 0.0 8.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.7 ORY00128.1 - 2.2e-11 43.5 4.0 2.9e-11 43.1 4.0 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY00128.1 - 0.31 11.0 4.6 1.4 8.9 4.6 1.9 1 1 0 1 1 1 0 F-box domain GDI PF00996.18 ORY00129.1 - 7.6e-226 749.6 0.4 8.9e-226 749.4 0.4 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DEAD PF00270.29 ORY00131.1 - 7.4e-48 162.6 0.1 2.1e-47 161.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY00131.1 - 2.7e-29 101.7 0.8 1.3e-28 99.5 0.0 2.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY00131.1 - 6.3e-06 26.3 0.3 2.1e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MtlR PF05068.12 ORY00131.1 - 0.11 12.5 0.4 0.27 11.2 0.4 1.6 1 0 0 1 1 1 0 Mannitol repressor Pkinase PF00069.25 ORY00132.1 - 1.9e-56 191.4 0.0 2.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00132.1 - 2.3e-31 109.1 0.0 3.2e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00132.1 - 5.5e-07 29.2 0.0 8.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY00132.1 - 0.03 14.2 0.0 2 8.3 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY00132.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY00132.1 - 0.12 11.1 0.2 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase ABC_membrane PF00664.23 ORY00133.1 - 3.1e-57 194.3 6.6 4e-57 193.9 6.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY00133.1 - 2.1e-33 115.7 0.0 5.2e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY00133.1 - 4e-08 33.0 0.0 4.3e-07 29.6 0.0 1.8 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 ORY00133.1 - 0.00045 19.6 0.0 0.00091 18.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 ORY00133.1 - 0.00085 18.5 0.0 0.002 17.2 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 ORY00133.1 - 0.0012 19.2 0.2 0.0041 17.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY00133.1 - 0.003 17.8 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY00133.1 - 0.0075 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 ORY00133.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY00133.1 - 0.014 15.0 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY00133.1 - 0.023 15.1 0.1 0.2 12.1 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ORY00133.1 - 0.029 14.1 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 ORY00133.1 - 0.063 13.8 0.0 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY00133.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 ORY00133.1 - 0.13 12.5 0.4 1.1 9.5 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit LEA_6 PF10714.9 ORY00134.1 - 0.037 14.1 1.7 0.069 13.2 1.7 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein 18 Bac_globin PF01152.21 ORY00135.1 - 5.8e-17 62.0 0.0 6.7e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin DUF4325 PF14213.6 ORY00135.1 - 0.0033 17.1 0.0 0.0083 15.8 0.0 1.6 1 1 0 1 1 1 1 STAS-like domain of unknown function (DUF4325) Protoglobin PF11563.8 ORY00136.1 - 1.5e-38 132.2 0.9 1.8e-38 132.0 0.9 1.0 1 0 0 1 1 1 1 Protoglobin tRNA-synt_1e PF01406.19 ORY00136.1 - 0.057 12.7 0.4 0.065 12.6 0.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain E1_dh PF00676.20 ORY00138.1 - 2.8e-97 325.3 0.1 3.2e-97 325.1 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 ORY00138.1 - 1.8e-06 27.2 0.1 2.3e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 ORY00138.1 - 4.7e-06 26.5 0.2 7.6e-05 22.5 0.2 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORY00138.1 - 0.0001 21.6 0.0 0.0004 19.7 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.8 ORY00138.1 - 0.11 12.1 0.3 0.33 10.7 0.3 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Phytochelatin PF05023.14 ORY00139.1 - 5.5e-71 238.2 0.0 6.8e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 ORY00139.1 - 3.8e-06 27.5 0.0 7.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase_C39 like family Ribosomal_L18A PF01775.17 ORY00140.1 - 1.7e-46 157.2 0.8 2.1e-46 156.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Aldo_ket_red PF00248.21 ORY00141.1 - 9.1e-70 235.2 0.0 1e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNARE_assoc PF09335.11 ORY00142.1 - 1.2e-17 64.4 7.7 1.2e-17 64.4 7.7 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2157 PF09925.9 ORY00142.1 - 0.042 13.6 2.4 5.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1772 PF08592.11 ORY00142.1 - 0.15 12.4 1.0 1.5 9.1 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2275 PF10039.9 ORY00142.1 - 0.28 11.3 1.2 0.75 9.9 0.1 2.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2275) CopD PF05425.13 ORY00142.1 - 0.88 10.0 5.0 7.7 7.0 0.9 3.0 2 1 1 3 3 3 0 Copper resistance protein D PDZ_1 PF12812.7 ORY00143.1 - 8.8e-38 128.2 0.0 1.4e-22 79.5 0.0 3.1 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 ORY00143.1 - 1.3e-22 81.4 0.2 5.1e-19 69.7 0.0 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 ORY00143.1 - 9.6e-21 73.9 0.0 9.6e-09 35.4 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 ORY00143.1 - 3.4e-19 68.4 0.0 4.4e-08 32.9 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORY00143.1 - 2.3e-12 47.1 0.0 2.6e-05 24.5 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 ORY00143.1 - 0.0008 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 ORY00143.1 - 0.00095 19.1 0.2 1.6 8.7 0.0 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain PDZ_3 PF17815.1 ORY00143.1 - 0.0091 15.9 0.1 17 5.3 0.0 3.9 4 1 1 5 5 5 1 PDZ domain DUF31 PF01732.16 ORY00143.1 - 0.19 11.2 0.5 0.29 10.6 0.5 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 ORY00143.1 - 0.29 9.7 0.0 2.2 6.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase S46 EB PF01683.18 ORY00144.1 - 3.3e-05 24.1 34.6 0.16 12.3 4.2 4.4 2 1 2 4 4 4 4 EB module LapA_dom PF06305.11 ORY00144.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 ORY00144.1 - 0.19 12.6 0.4 1.1 10.2 0.1 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 ORY00144.1 - 0.27 11.5 0.0 0.27 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) 3HCDH_N PF02737.18 ORY00145.1 - 3.2e-56 190.1 1.1 4.2e-56 189.7 1.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY00145.1 - 1.6e-34 118.4 0.0 3.2e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY00145.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-RING_2 PF13639.6 ORY00146.1 - 2e-14 53.6 6.9 4e-14 52.7 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY00146.1 - 5.5e-11 42.0 5.3 5.5e-11 42.0 5.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY00146.1 - 3.1e-09 36.6 5.7 6.7e-09 35.5 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 ORY00146.1 - 7.1e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 ORY00146.1 - 1.3e-08 34.5 5.8 1.3e-08 34.5 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY00146.1 - 1.7e-07 31.0 3.9 1.7e-07 31.0 3.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY00146.1 - 3.3e-07 30.5 8.7 2e-06 28.0 8.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY00146.1 - 5.3e-05 23.2 1.9 0.00011 22.2 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY00146.1 - 0.00017 21.6 1.2 0.00017 21.6 1.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY00146.1 - 0.00028 20.7 6.6 0.0005 19.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY00146.1 - 0.001 18.9 7.0 0.0023 17.8 7.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY00146.1 - 0.0065 16.2 6.8 0.012 15.4 6.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORY00146.1 - 0.012 15.8 2.7 0.031 14.4 2.7 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 ORY00146.1 - 0.042 13.7 4.9 0.084 12.8 4.9 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ORY00146.1 - 0.22 11.7 6.5 1.1 9.5 6.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY00146.1 - 0.57 9.8 4.0 1.2 8.8 4.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 ORY00146.1 - 1 9.7 4.6 0.52 10.7 1.8 1.9 2 0 0 2 2 2 0 RING-like domain AMP-binding PF00501.28 ORY00193.1 - 6.6e-136 453.3 0.0 4.8e-99 331.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ORY00193.1 - 1.5e-47 162.3 0.0 2.1e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Thioesterase PF00975.20 ORY00193.1 - 4.8e-31 108.7 0.0 1.5e-30 107.0 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 ORY00193.1 - 6.2e-31 107.2 0.1 3.3e-14 53.6 0.1 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ORY00193.1 - 3.5e-27 94.6 0.3 1.1e-12 48.2 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 ORY00193.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 ORY00194.1 - 4.5e-117 391.7 29.7 1.8e-83 280.9 19.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY00194.1 - 6.2e-32 110.9 37.6 3.9e-30 105.0 19.6 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY00194.1 - 0.00015 20.4 3.1 0.00015 20.4 3.1 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Saf_2TM PF18303.1 ORY00194.1 - 4.6 6.8 7.7 1.6 8.3 1.8 2.9 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain LRR_6 PF13516.6 ORY00195.1 - 6e-26 88.3 17.2 0.00025 20.9 0.1 10.8 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 ORY00195.1 - 4.5e-11 42.8 18.5 0.1 13.0 0.7 8.4 4 2 6 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY00195.1 - 4.2e-09 36.0 23.4 0.018 14.8 0.2 7.7 3 3 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY00195.1 - 7.8e-05 22.7 12.9 51 5.0 0.0 9.7 10 2 1 11 11 11 0 Leucine Rich Repeat COX5A PF02284.16 ORY00195.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va MIP PF00230.20 ORY00196.1 - 9.2e-58 195.6 10.0 1.1e-57 195.4 10.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein RIH_assoc PF08454.11 ORY00198.1 - 2.6e-20 72.1 3.1 2.6e-20 72.1 3.1 4.5 4 0 0 4 4 4 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 ORY00198.1 - 3.8e-20 72.2 10.0 1e-17 64.3 1.3 3.6 3 0 0 3 3 3 2 RIH domain Ins145_P3_rec PF08709.11 ORY00198.1 - 1.9e-15 56.6 0.0 4.3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 ORY00198.1 - 2.6e-13 50.2 0.4 2.8e-10 40.3 0.0 2.7 2 0 0 2 2 2 2 MIR domain Ion_trans PF00520.31 ORY00198.1 - 8.3e-12 44.8 5.9 8.3e-12 44.8 5.9 1.9 2 0 0 2 2 2 1 Ion transport protein Man-6-P_recep PF02157.15 ORY00198.1 - 0.031 13.4 0.6 0.057 12.5 0.0 1.7 2 0 0 2 2 2 0 Mannose-6-phosphate receptor DUF3361 PF11841.8 ORY00198.1 - 0.048 13.6 0.5 0.94 9.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) MAM33 PF02330.16 ORY00199.1 - 5.9e-67 225.7 7.2 6.8e-67 225.5 7.2 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein PAPS_reduct PF01507.19 ORY00200.1 - 8e-41 140.0 0.0 9.2e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SPRY PF00622.28 ORY00201.1 - 2.7e-24 85.6 0.3 6.2e-24 84.4 0.3 1.6 1 0 0 1 1 1 1 SPRY domain XPG_I PF00867.18 ORY00203.1 - 3.5e-25 88.2 0.1 7.4e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY00203.1 - 4.4e-25 88.1 0.0 1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ORY00203.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_1 PF00515.28 ORY00203.1 - 0.00057 19.6 0.7 0.0033 17.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat 5_3_exonuc PF01367.20 ORY00203.1 - 0.0015 19.1 0.0 0.0051 17.4 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_8 PF13181.6 ORY00203.1 - 0.0016 18.5 0.2 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY00203.1 - 0.0029 17.6 0.2 0.026 14.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HHH_5 PF14520.6 ORY00203.1 - 0.0084 16.7 0.1 0.21 12.2 0.1 2.5 2 1 0 2 2 2 1 Helix-hairpin-helix domain RPN7 PF10602.9 ORY00203.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Ribosomal_L22 PF00237.19 ORY00203.1 - 0.16 12.2 0.1 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e Alk_phosphatase PF00245.20 ORY00204.1 - 7e-103 344.8 0.0 9.1e-103 344.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF1729 PF08354.10 ORY00204.1 - 0.0027 16.6 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Metalloenzyme PF01676.18 ORY00204.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily Cyclin PF08613.11 ORY00205.1 - 3.7e-11 43.7 0.0 4.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin FemAB PF02388.16 ORY00205.1 - 0.072 12.0 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 FemAB family LCM PF04072.14 ORY00206.1 - 1.8e-26 93.3 0.0 6.8e-26 91.4 0.0 1.9 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase GATase_4 PF13230.6 ORY00208.1 - 2.5e-18 65.9 0.1 1.8e-17 63.2 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 ORY00208.1 - 1.1e-11 45.0 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pkinase PF00069.25 ORY00209.1 - 3.5e-69 233.1 0.0 7.1e-69 232.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00209.1 - 1e-42 146.2 0.0 2e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY00209.1 - 0.0007 18.5 0.3 0.0041 15.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY00209.1 - 0.00076 18.9 0.4 0.016 14.6 0.1 2.7 3 1 0 3 3 3 1 Kinase-like APH PF01636.23 ORY00209.1 - 0.001 19.1 0.1 0.0022 17.9 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY00209.1 - 0.0018 17.4 0.2 0.0034 16.5 0.2 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 YjcQ PF09639.10 ORY00209.1 - 0.09 13.0 0.1 0.55 10.5 0.0 2.5 3 0 0 3 3 3 0 YjcQ protein bZIP_1 PF00170.21 ORY00211.1 - 2.6e-09 37.0 14.2 2.6e-09 37.0 14.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY00211.1 - 4.9e-07 29.7 15.9 4.9e-07 29.7 15.9 2.6 3 0 0 3 3 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY00211.1 - 0.0032 18.0 12.9 0.0051 17.3 12.0 1.8 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.8 ORY00211.1 - 0.0034 16.7 8.3 0.0053 16.1 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 ORY00211.1 - 0.0052 16.8 10.4 0.0094 16.0 10.4 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Macoilin PF09726.9 ORY00211.1 - 0.014 14.0 5.8 0.025 13.2 5.8 1.3 1 0 0 1 1 1 0 Macoilin family ADIP PF11559.8 ORY00211.1 - 0.017 15.2 12.1 0.017 15.2 12.1 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Dynamitin PF04912.14 ORY00211.1 - 0.018 14.4 9.7 0.029 13.7 9.7 1.2 1 0 0 1 1 1 0 Dynamitin Fib_alpha PF08702.10 ORY00211.1 - 0.019 15.2 2.8 0.035 14.3 2.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF677 PF05055.12 ORY00211.1 - 0.024 13.6 0.4 0.034 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) ZapB PF06005.12 ORY00211.1 - 0.03 14.8 13.1 0.061 13.8 13.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 ORY00211.1 - 0.034 14.6 2.7 0.034 14.6 2.7 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 ORY00211.1 - 0.041 13.6 11.6 0.055 13.2 9.9 2.0 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.11 ORY00211.1 - 0.042 14.1 15.9 0.081 13.1 15.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 ORY00211.1 - 0.047 14.0 6.8 0.087 13.1 6.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 VIT1 PF01988.19 ORY00211.1 - 0.053 13.4 0.4 0.093 12.6 0.4 1.3 1 0 0 1 1 1 0 VIT family KASH_CCD PF14662.6 ORY00211.1 - 0.055 13.3 13.9 0.095 12.5 13.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 ORY00211.1 - 0.082 10.4 9.5 0.11 10.0 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rota_NSP3 PF01665.16 ORY00211.1 - 0.094 11.8 2.4 0.14 11.3 2.4 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Leu_zip PF15294.6 ORY00211.1 - 0.14 11.7 10.2 0.24 10.9 10.2 1.3 1 0 0 1 1 1 0 Leucine zipper FTA4 PF13093.6 ORY00211.1 - 0.16 11.9 6.2 0.11 12.3 4.2 1.7 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4201 PF13870.6 ORY00211.1 - 0.23 11.2 12.8 0.37 10.5 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) YabA PF06156.13 ORY00211.1 - 0.31 11.7 7.0 0.86 10.3 7.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DUF4404 PF14357.6 ORY00211.1 - 0.34 11.6 8.9 0.79 10.4 8.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Fmp27_WPPW PF10359.9 ORY00211.1 - 0.41 9.4 9.3 0.6 8.9 9.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 ORY00211.1 - 0.46 9.7 4.8 0.72 9.0 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cnn_1N PF07989.11 ORY00211.1 - 0.48 10.6 9.8 0.43 10.8 7.8 1.9 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 ORY00211.1 - 0.63 10.1 3.9 1.1 9.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2009 PF09418.10 ORY00211.1 - 0.73 8.8 3.9 1.1 8.2 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Herpes_UL25 PF01499.16 ORY00211.1 - 0.79 8.2 4.6 1.2 7.6 4.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family HALZ PF02183.18 ORY00211.1 - 1 9.6 9.4 0.065 13.5 2.7 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper Herpes_UL6 PF01763.16 ORY00211.1 - 1.1 7.7 4.2 1.5 7.2 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like HAUS6_N PF14661.6 ORY00211.1 - 1.1 8.8 8.5 1.8 8.1 8.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 ORY00211.1 - 1.1 9.7 16.5 2.4 8.7 16.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Dzip-like_N PF13815.6 ORY00211.1 - 1.1 9.2 6.8 2.2 8.3 6.8 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Spc7 PF08317.11 ORY00211.1 - 1.3 7.9 12.4 1.9 7.3 12.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 ORY00211.1 - 1.7 8.7 10.3 3.3 7.8 10.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 ORY00211.1 - 2 7.7 7.5 3.3 7.0 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 ORY00211.1 - 2.2 6.1 5.1 3.1 5.6 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1640 PF07798.11 ORY00211.1 - 3.2 7.8 11.8 5.7 7.0 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CENP-H PF05837.12 ORY00211.1 - 3.6 8.0 12.9 8.3 6.9 12.9 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Prominin PF05478.11 ORY00211.1 - 4.4 5.1 5.1 6.6 4.6 5.1 1.2 1 0 0 1 1 1 0 Prominin Troponin PF00992.20 ORY00211.1 - 5.2 7.4 16.4 9.7 6.5 16.4 1.3 1 0 0 1 1 1 0 Troponin KfrA_N PF11740.8 ORY00211.1 - 5.5 7.7 19.8 55 4.5 15.8 2.8 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Nop25 PF09805.9 ORY00211.1 - 5.8 7.4 12.9 14 6.1 12.9 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Atg14 PF10186.9 ORY00211.1 - 6.4 5.8 9.8 12 4.9 9.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 ORY00211.1 - 8.5 6.2 11.5 16 5.3 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DIL PF01843.19 ORY00212.1 - 1.8e-26 92.4 3.0 4.2e-26 91.2 3.0 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 ORY00212.1 - 4.1e-13 49.7 0.1 9e-07 29.4 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY00212.1 - 1.3e-12 47.7 0.0 5.8e-07 29.7 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY00212.1 - 1.2e-09 38.2 0.1 0.00084 19.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY00212.1 - 2.3e-08 34.4 0.0 0.00035 21.1 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY00212.1 - 0.00087 19.6 0.1 2.6 8.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat 2-Hacid_dh_C PF02826.19 ORY00213.1 - 2.9e-58 196.1 0.0 4.1e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY00213.1 - 2.5e-30 104.9 0.0 3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY00213.1 - 7.4e-05 23.0 0.0 0.0002 21.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ORY00213.1 - 0.00022 21.3 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ORY00213.1 - 0.00085 19.9 0.1 0.0034 17.9 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ORY00213.1 - 0.0025 17.4 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 ORY00213.1 - 0.021 15.3 0.2 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 ORY00213.1 - 0.049 14.5 0.0 0.091 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AdoHcyase_NAD PF00670.21 ORY00213.1 - 0.08 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Velvet PF11754.8 ORY00214.1 - 2.3e-48 165.4 1.5 9.1e-24 84.8 0.7 2.6 1 1 1 2 2 2 2 Velvet factor zf-C2H2 PF00096.26 ORY00215.1 - 2.1e-11 43.6 11.0 2.5e-05 24.5 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY00215.1 - 2.2e-10 40.5 9.9 1.6e-05 25.1 1.0 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY00215.1 - 4e-08 33.4 9.9 0.0011 19.7 3.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY00215.1 - 2.5e-07 30.8 8.5 1.8e-05 25.0 2.0 2.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY00215.1 - 2.9e-07 30.6 4.4 8.5e-05 22.7 2.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY00215.1 - 0.00011 22.1 7.4 0.016 15.2 2.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger THAP PF05485.12 ORY00215.1 - 0.00093 20.1 2.0 0.93 10.5 0.4 2.2 2 0 0 2 2 2 2 THAP domain zf-H2C2_5 PF13909.6 ORY00215.1 - 0.0012 18.6 1.6 0.15 11.9 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 ORY00215.1 - 0.011 16.0 2.8 0.025 14.9 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 ORY00215.1 - 0.061 13.3 0.9 1 9.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 ORY00215.1 - 0.085 12.9 6.1 38 4.4 6.1 2.4 1 1 0 1 1 1 0 BED zinc finger Cytochrom_C550 PF14495.6 ORY00215.1 - 0.092 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain Zn_ribbon_SprT PF17283.2 ORY00215.1 - 1.1 9.3 6.8 0.11 12.4 1.9 1.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DM PF00751.18 ORY00215.1 - 3.1 7.8 6.7 8.6 6.4 6.1 2.0 1 1 0 1 1 1 0 DM DNA binding domain Peptidase_S9 PF00326.21 ORY00216.1 - 5.2e-59 199.3 0.2 8.1e-59 198.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORY00216.1 - 6.4e-09 35.5 8.2 0.078 12.9 0.2 5.0 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 ORY00216.1 - 1.6e-05 24.7 2.7 0.11 12.0 1.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORY00216.1 - 0.00024 19.9 0.1 0.004 15.9 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 ORY00216.1 - 0.0003 21.4 0.1 0.00053 20.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY00216.1 - 0.00059 19.6 4.0 0.34 10.5 1.7 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 ORY00216.1 - 0.0032 16.4 0.5 0.0057 15.6 0.5 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF2920 PF11144.8 ORY00216.1 - 0.024 13.8 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Chlorophyllase2 PF12740.7 ORY00216.1 - 0.079 11.9 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 ORY00216.1 - 0.091 11.3 0.1 0.29 9.6 0.0 1.9 2 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 ORY00217.1 - 6.4e-57 192.4 1.4 6.8e-57 192.3 0.5 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 ORY00217.1 - 3e-09 36.6 9.7 0.038 13.9 0.0 5.3 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat AXE1 PF05448.12 ORY00217.1 - 0.00015 20.6 0.0 0.0088 14.8 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 ORY00217.1 - 0.0044 16.7 2.4 1.9 8.1 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Copper-bind PF00127.20 ORY00218.1 - 0.00021 21.7 0.0 0.00042 20.7 0.0 1.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 ORY00218.1 - 0.0019 18.1 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain TM_helix PF05552.12 ORY00218.1 - 0.85 9.6 3.8 1.4 8.9 3.8 1.4 1 0 0 1 1 1 0 Conserved TM helix IML1 PF12257.8 ORY00219.1 - 1.8e-119 398.1 0.9 3.3e-119 397.2 0.9 1.5 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 ORY00219.1 - 1.8e-23 82.4 0.2 3.8e-23 81.3 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Histone PF00125.24 ORY00220.1 - 3.2e-52 176.4 2.7 3.5e-52 176.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY00220.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY00220.1 - 3e-05 24.1 0.4 4.8e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY00220.1 - 0.00018 22.1 1.1 0.00021 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY00220.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY00220.1 - 0.055 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY00220.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated GalKase_gal_bdg PF10509.9 ORY00221.1 - 3.7e-22 77.6 0.1 8.2e-22 76.5 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 ORY00221.1 - 5.2e-14 52.4 0.0 8.2e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ORY00221.1 - 5.8e-14 52.1 1.3 1.2e-13 51.1 1.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain zf-Tim10_DDP PF02953.15 ORY00261.1 - 3.7e-21 74.5 1.5 4.7e-21 74.2 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Baculo_gp41 PF04700.12 ORY00261.1 - 0.036 13.8 0.2 0.043 13.6 0.2 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Zn_clus PF00172.18 ORY00262.1 - 3.6e-05 23.8 16.0 6e-05 23.1 16.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCI PF01399.27 ORY00263.1 - 1.9e-08 34.7 0.1 1.9e-08 34.7 0.1 3.5 4 0 0 4 4 4 1 PCI domain VF530 PF09905.9 ORY00263.1 - 0.023 14.9 0.0 3.6 7.8 0.0 2.9 3 0 0 3 3 3 0 DNA-binding protein VF530 DUF4042 PF13251.6 ORY00264.1 - 4.3e-36 124.3 5.0 1.2e-35 122.9 0.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 ORY00264.1 - 3.1e-14 53.1 0.2 0.0044 17.4 0.0 7.5 7 3 2 9 9 9 4 HEAT repeats HEAT PF02985.22 ORY00264.1 - 6.5e-09 35.3 18.6 0.00044 20.3 0.1 9.8 11 0 0 11 11 11 1 HEAT repeat IFRD PF05004.13 ORY00264.1 - 1.5e-06 27.5 9.2 0.11 11.6 0.0 5.2 3 3 2 6 6 6 3 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 ORY00264.1 - 2.8e-06 27.7 9.8 0.028 14.9 0.1 7.5 8 1 1 9 9 9 2 HEAT-like repeat Arm PF00514.23 ORY00264.1 - 0.0011 18.9 7.5 0.06 13.4 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HSM3_N PF18795.1 ORY00264.1 - 0.0019 17.7 3.0 0.18 11.2 0.3 2.5 2 0 0 2 2 2 2 DNA mismatch repair protein HSM3, N terminal domain TAF6_C PF07571.13 ORY00264.1 - 0.0057 17.0 2.8 4.7 7.6 0.2 3.8 4 0 0 4 4 4 2 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 ORY00264.1 - 0.011 16.3 1.1 2.6 8.7 0.0 4.7 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 ORY00264.1 - 0.048 13.6 13.3 9.4 6.1 0.2 5.9 5 2 1 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal LSM PF01423.22 ORY00265.1 - 3.9e-22 77.7 0.0 4.3e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY00265.1 - 1.1e-05 25.4 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_S8 PF00082.22 ORY00266.1 - 5.8e-35 121.0 15.7 1.5e-34 119.6 15.7 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY00266.1 - 0.00065 20.3 0.5 0.0012 19.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 TRAM_LAG1_CLN8 PF03798.16 ORY00267.1 - 6.1e-43 146.9 33.5 1.9e-42 145.2 29.5 2.2 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 ORY00267.1 - 6.6e-21 73.7 0.1 6.6e-21 73.7 0.1 2.7 3 0 0 3 3 3 1 TRAM1-like protein Pkinase PF00069.25 ORY00268.1 - 2.3e-38 132.1 0.0 3.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00268.1 - 1.2e-14 54.2 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY00268.1 - 7.5e-08 32.6 0.2 7.3e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY00268.1 - 1.7e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 ORY00268.1 - 0.00026 19.9 0.0 0.00035 19.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY00268.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 ORY00268.1 - 0.0098 15.0 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 ORY00268.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 ORY00268.1 - 0.023 14.1 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.27 ORY00268.1 - 0.033 14.0 0.0 0.12 12.1 0.0 1.9 3 0 0 3 3 3 0 Phosphatidylinositol 3- and 4-kinase bZIP_2 PF07716.15 ORY00269.1 - 1.4e-10 41.1 11.0 2.6e-10 40.2 11.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 ORY00269.1 - 0.011 16.0 2.6 0.021 15.0 2.6 1.5 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_1 PF00170.21 ORY00269.1 - 0.033 14.3 7.5 0.064 13.4 7.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor Prenyltrans PF00432.21 ORY00270.1 - 1.6e-50 168.5 11.5 4.5e-11 42.3 0.0 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 ORY00270.1 - 0.0015 17.7 0.0 0.061 12.4 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 ORY00270.1 - 0.2 10.7 0.0 2.3 7.2 0.0 2.4 1 1 2 3 3 3 0 Squalene-hopene cyclase C-terminal domain Exo_endo_phos PF03372.23 ORY00272.1 - 1.2e-07 31.5 0.0 3.6e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin_7 PF13899.6 ORY00273.1 - 1.4e-16 60.5 0.1 3.9e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 ORY00273.1 - 1.6e-13 50.2 0.0 3.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 ORY00273.1 - 7.5e-11 42.1 0.0 2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 ORY00273.1 - 0.0037 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain PHP PF02811.19 ORY00274.1 - 2.1e-13 50.9 0.3 5.6e-13 49.5 0.3 1.8 1 1 0 1 1 1 1 PHP domain Pkinase PF00069.25 ORY00275.1 - 6.5e-70 235.5 0.0 9e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 ORY00275.1 - 4.7e-59 199.8 6.0 1.4e-58 198.2 6.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 ORY00275.1 - 1.8e-44 152.0 0.0 2.4e-43 148.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY00275.1 - 0.0054 15.6 0.0 0.024 13.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY00275.1 - 0.014 15.3 0.0 0.052 13.5 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY00275.1 - 0.046 13.0 0.0 0.82 8.9 0.0 2.4 1 1 0 1 1 1 0 Kinase-like Hydantoinase_B PF02538.14 ORY00276.1 - 3.3e-219 728.6 0.0 4.4e-219 728.2 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY00276.1 - 3e-108 361.5 0.0 9.5e-108 359.9 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY00276.1 - 4.2e-63 212.3 0.1 1e-60 204.5 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region PAN_4 PF14295.6 ORY00276.1 - 0.058 13.3 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 PAN domain RBFA PF02033.18 ORY00277.1 - 2.2e-06 28.1 0.0 5.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ribosome-binding factor A Ribosomal_L22e PF01776.17 ORY00277.1 - 0.074 13.4 0.3 0.12 12.8 0.3 1.2 1 0 0 1 1 1 0 Ribosomal L22e protein family Dopey_N PF04118.14 ORY00279.1 - 2.5e-113 378.2 3.2 7.4e-113 376.7 1.0 2.7 2 0 0 2 2 2 1 Dopey, N-terminal Ribosomal_S5 PF00333.20 ORY00280.1 - 3.2e-30 103.9 0.6 3.2e-30 103.9 0.6 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORY00280.1 - 7.5e-26 89.4 0.1 1.2e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORY00280.1 - 0.59 10.7 10.1 1.1 9.8 10.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 NOB1_Zn_bind PF08772.11 ORY00281.1 - 8.7e-33 112.3 2.0 1.6e-32 111.5 2.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 ORY00281.1 - 4.5e-28 97.6 0.0 9.1e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease DZR PF12773.7 ORY00281.1 - 0.034 14.2 0.3 0.06 13.4 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon E6 PF00518.17 ORY00281.1 - 0.035 14.5 0.4 0.066 13.7 0.4 1.4 1 0 0 1 1 1 0 Early Protein (E6) WRNPLPNID PF15017.6 ORY00281.1 - 0.046 14.6 10.1 0.046 14.6 10.1 1.8 1 1 1 2 2 2 0 Putative WW-binding domain and destruction box zinc_ribbon_15 PF17032.5 ORY00281.1 - 0.046 14.5 0.1 0.09 13.5 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon family Cwf_Cwc_15 PF04889.12 ORY00281.1 - 0.076 12.7 5.5 0.11 12.2 5.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR19-TM PF15176.6 ORY00281.1 - 0.15 12.1 2.5 0.3 11.1 2.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FAA_hydrolase PF01557.18 ORY00282.1 - 2.9e-58 197.1 0.0 3.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 ORY00282.1 - 0.14 12.0 2.0 0.15 11.9 0.0 2.0 3 0 0 3 3 3 0 KH domain Porphobil_deam PF01379.20 ORY00283.1 - 2.8e-81 271.9 0.0 3.4e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ORY00283.1 - 2e-17 63.3 0.0 4.1e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TAL_FSA PF00923.19 ORY00284.1 - 4.4e-101 338.0 0.1 5e-101 337.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase MBOAT PF03062.19 ORY00285.1 - 1.1e-47 163.1 13.6 1.1e-47 163.1 13.6 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family RIBIOP_C PF04950.12 ORY00286.1 - 1.9e-121 405.0 0.9 2.7e-121 404.5 0.0 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY00286.1 - 7.9e-23 80.4 0.0 1.9e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Amidohydro_1 PF01979.20 ORY00287.1 - 4.1e-37 128.3 0.0 6.7e-18 65.1 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ORY00287.1 - 0.00071 19.2 0.1 0.41 10.1 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family FAD_binding_4 PF01565.23 ORY00287.1 - 0.13 12.1 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Hydrolase PF00702.26 ORY00329.1 - 2.7e-11 44.1 0.6 3.4e-11 43.8 0.6 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY00329.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HTH_AsnC-type PF13404.6 ORY00329.1 - 0.017 15.0 0.8 0.052 13.4 0.0 2.2 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HAD PF12710.7 ORY00329.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 ORY00330.1 - 6.3e-68 229.6 0.1 4.9e-67 226.7 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF1863 PF08937.11 ORY00330.1 - 0.02 15.2 2.6 0.42 10.9 0.0 2.7 2 1 1 3 3 3 0 MTH538 TIR-like domain (DUF1863) UCH PF00443.29 ORY00330.1 - 0.039 13.4 0.0 0.054 13.0 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase p450 PF00067.22 ORY00331.1 - 7.5e-67 226.1 0.1 6.6e-66 223.0 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 SPC12 PF06645.13 ORY00331.1 - 0.018 15.1 0.0 0.34 11.0 0.0 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) p450 PF00067.22 ORY00332.1 - 7.7e-66 222.7 0.4 5.7e-65 219.9 0.4 2.0 1 1 0 1 1 1 1 Cytochrome P450 SH3_1 PF00018.28 ORY00333.1 - 1e-25 89.1 1.5 1.4e-12 47.0 0.1 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY00333.1 - 1.8e-22 78.8 0.3 1.4e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 ORY00333.1 - 1.5e-19 69.6 0.3 5.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain LON_substr_bdg PF02190.16 ORY00335.1 - 1.4e-26 93.7 0.0 1.8e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-RING_UBOX PF13445.6 ORY00335.1 - 4.1e-11 42.7 26.8 4.9e-07 29.7 6.0 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY00335.1 - 5.5e-11 42.4 26.6 2.9e-05 24.1 7.2 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORY00335.1 - 8.5e-11 41.5 10.3 8.5e-11 41.5 10.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY00335.1 - 8.6e-09 35.1 27.2 5.6e-07 29.3 9.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY00335.1 - 1.2e-07 31.4 21.5 1.7e-06 27.8 6.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY00335.1 - 1.6e-06 28.0 26.3 3e-06 27.1 9.0 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 ORY00335.1 - 1.8e-05 24.9 10.2 1.8e-05 24.9 10.2 3.1 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 ORY00335.1 - 6.9e-05 22.6 23.7 0.00027 20.7 7.7 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY00335.1 - 0.00051 20.1 9.3 0.00051 20.1 9.3 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 ORY00335.1 - 0.18 12.0 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 U-box domain DUF390 PF04094.14 ORY00335.1 - 0.54 8.5 0.7 0.8 7.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf_C2H2_10 PF18414.1 ORY00335.1 - 0.83 9.2 8.1 3.3 7.3 0.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger CK_II_beta PF01214.18 ORY00336.1 - 6.6e-73 244.4 0.0 9.2e-73 243.9 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MFS_1 PF07690.16 ORY00337.1 - 3.4e-29 101.9 42.0 3.4e-29 101.9 42.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY00337.1 - 0.00012 21.1 1.6 0.00012 21.1 1.6 2.9 2 2 1 3 3 3 2 Sugar (and other) transporter Homeodomain PF00046.29 ORY00338.1 - 4e-11 42.6 1.2 4e-11 42.6 1.2 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY00338.1 - 5.7 6.9 9.8 0.56 10.1 0.2 2.9 3 0 0 3 3 3 0 Homeobox KN domain Lactamase_B PF00753.27 ORY00339.1 - 1.3e-16 61.2 0.0 1.7e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY00339.1 - 2.7e-05 23.8 0.1 4.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acyltransferase PF01553.21 ORY00340.1 - 1.8e-36 124.7 0.0 2.8e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Folliculin_C PF16692.5 ORY00340.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Folliculin C-terminal domain LRR_8 PF13855.6 ORY00341.1 - 3.7e-12 45.8 16.7 9.8e-07 28.4 1.8 3.6 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY00341.1 - 4.1e-11 42.9 12.4 0.00033 21.0 0.0 4.2 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY00341.1 - 6e-06 26.1 13.4 1.7 9.5 0.0 6.5 6 1 0 6 6 6 3 Leucine Rich Repeat YCII PF03795.14 ORY00342.1 - 7.6e-14 51.9 0.0 8.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Glyco_transf_5 PF08323.11 ORY00343.1 - 3.5e-22 79.3 0.1 5.6e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 ORY00343.1 - 1.9e-13 50.3 0.0 3.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY00343.1 - 2e-09 38.0 0.0 4.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY00343.1 - 1.4e-05 25.1 0.0 0.00045 20.3 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY00343.1 - 0.0004 20.9 0.0 0.0026 18.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain vATP-synt_E PF01991.18 ORY00343.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit SPRY PF00622.28 ORY00344.1 - 6e-14 52.2 1.3 6.4e-07 29.5 0.0 3.6 4 0 0 4 4 4 2 SPRY domain Forkhead PF00250.18 ORY00344.1 - 0.036 14.3 0.2 0.082 13.2 0.2 1.5 1 0 0 1 1 1 0 Forkhead domain PHD PF00628.29 ORY00344.1 - 0.22 11.5 7.9 0.41 10.6 7.9 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 ORY00344.1 - 0.53 10.2 7.2 0.18 11.7 3.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0052 PF01933.18 ORY00345.1 - 6.8e-51 173.2 0.0 8.6e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Peptidase_S66 PF02016.15 ORY00345.1 - 0.1 12.7 0.1 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain OAD_beta PF03977.13 ORY00345.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Form_Nir_trans PF01226.17 ORY00346.1 - 1.5e-67 227.4 21.9 1.7e-67 227.2 21.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Tubulin PF00091.25 ORY00347.1 - 1.3e-68 231.1 0.0 2e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY00347.1 - 3.3e-52 175.9 0.0 5.3e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY00347.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.21 ORY00348.1 - 1.1e-15 57.4 12.2 1.1e-15 57.4 12.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY00348.1 - 1.8e-14 53.6 15.7 3.4e-14 52.7 15.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY00348.1 - 3.4e-06 27.5 5.9 3.4e-06 27.5 5.9 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor GIT_CC PF16559.5 ORY00348.1 - 0.00091 19.0 1.9 0.002 18.0 1.9 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor SSXT PF05030.12 ORY00348.1 - 0.0075 15.9 0.8 0.015 14.9 0.8 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) ASD2 PF08687.11 ORY00348.1 - 0.0093 15.6 5.5 0.012 15.2 5.5 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Fungal_TACC PF12709.7 ORY00348.1 - 0.014 15.9 3.6 0.031 14.7 3.6 1.6 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 ORY00348.1 - 0.032 14.6 1.2 0.083 13.2 1.2 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family TMCO5 PF14992.6 ORY00348.1 - 0.046 13.3 5.3 0.064 12.8 5.3 1.2 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.15 ORY00348.1 - 0.072 12.9 4.3 0.15 11.8 4.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 ORY00348.1 - 0.13 10.8 12.4 0.16 10.5 12.4 1.1 1 0 0 1 1 1 0 Macoilin family SID-1_RNA_chan PF13965.6 ORY00348.1 - 0.2 10.1 1.3 0.21 9.9 1.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CASP_C PF08172.12 ORY00348.1 - 0.34 10.2 13.8 3.2 7.0 0.1 2.6 1 1 1 2 2 2 0 CASP C terminal Kri1 PF05178.12 ORY00348.1 - 3.5 8.2 7.6 6.7 7.3 7.6 1.5 1 0 0 1 1 1 0 KRI1-like family Amidase PF01425.21 ORY00350.1 - 4.9e-80 269.7 0.0 3.3e-74 250.5 0.0 2.0 1 1 1 2 2 2 2 Amidase DUF4209 PF13910.6 ORY00351.1 - 3.3e-20 72.1 0.8 4.6e-19 68.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4209) DJ-1_PfpI PF01965.24 ORY00352.1 - 1.1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY00352.1 - 0.00028 20.7 0.0 0.00097 18.9 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORY00352.1 - 0.0021 17.8 0.1 0.0056 16.4 0.0 1.6 1 1 0 1 1 1 1 Latrotoxin C-terminal domain GST_N_3 PF13417.6 ORY00353.1 - 1.6e-13 50.8 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY00353.1 - 3.8e-12 46.3 0.3 1.1e-11 44.9 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY00353.1 - 2.4e-10 40.6 0.0 5.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY00353.1 - 8e-09 35.6 0.0 1.5e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY00353.1 - 3.4e-07 30.2 0.0 6.9e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY00353.1 - 3.1e-06 27.3 0.0 1.1e-05 25.5 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY00353.1 - 1.2e-05 25.9 0.0 0.00019 22.0 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY00353.1 - 0.0015 18.4 0.2 0.0062 16.4 0.1 2.2 2 1 0 2 2 2 1 Glutaredoxin 2, C terminal domain APH PF01636.23 ORY00400.1 - 2e-33 116.3 0.0 2.9e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY00400.1 - 0.0001 21.7 0.0 0.00022 20.6 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase DUF2264 PF10022.9 ORY00400.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) PBD PF00786.28 ORY00402.1 - 6.4e-25 87.3 0.0 7.4e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.25 ORY00403.1 - 3.1e-74 249.7 0.0 3.7e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00403.1 - 1.1e-48 165.7 0.0 1.7e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00403.1 - 2.5e-07 30.3 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY00403.1 - 8.1e-06 24.9 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY00403.1 - 0.0008 19.4 0.0 0.037 14.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY00403.1 - 0.0056 16.1 0.1 0.07 12.5 0.0 2.0 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY00403.1 - 0.0057 15.6 0.6 0.023 13.7 0.6 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY00403.1 - 0.049 12.7 0.1 0.077 12.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DSHCT PF08148.12 ORY00403.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain FTA2 PF13095.6 ORY00403.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cyclin_C_2 PF16899.5 ORY00404.1 - 1.3e-20 73.8 6.3 4.5e-19 68.8 0.1 2.7 3 1 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 ORY00404.1 - 9.1e-13 48.1 0.2 4.4e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY00404.1 - 0.00037 20.5 0.0 0.00089 19.3 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ATP-synt_J PF04911.12 ORY00405.1 - 6.6e-24 83.2 0.6 7.4e-24 83.1 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain CDP-OH_P_transf PF01066.21 ORY00406.1 - 2.2e-16 60.4 0.1 2.2e-16 60.4 0.1 3.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Fst_toxin PF13955.6 ORY00406.1 - 0.31 11.0 5.4 0.13 12.2 2.3 2.2 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Arrestin_N PF00339.29 ORY00407.1 - 3.1e-13 50.0 0.1 1.4e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY00407.1 - 8e-10 39.3 0.0 1.3e-06 28.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY00407.1 - 0.0031 17.3 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Myb_DNA-bind_4 PF13837.6 ORY00408.1 - 9.4e-19 67.6 1.6 1.3e-18 67.1 1.6 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY00408.1 - 2.2e-07 31.0 1.3 4.2e-07 30.1 1.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY00408.1 - 4.6e-06 26.7 0.5 1.2e-05 25.4 0.7 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY00408.1 - 0.0001 22.5 1.0 0.00018 21.7 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORY00408.1 - 0.002 19.1 0.7 0.0035 18.3 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HMG_box_2 PF09011.10 ORY00408.1 - 0.027 15.1 0.9 0.046 14.3 0.9 1.4 1 0 0 1 1 1 0 HMG-box domain Ribosomal_S11 PF00411.19 ORY00409.1 - 1.2e-47 160.8 1.3 1.5e-47 160.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 TPR_MLP1_2 PF07926.12 ORY00410.1 - 0.00092 19.3 7.0 0.00092 19.3 7.0 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Kinesin PF00225.23 ORY00411.1 - 0.00078 18.5 0.0 0.00078 18.5 0.0 2.4 3 0 0 3 3 3 1 Kinesin motor domain PspA_IM30 PF04012.12 ORY00411.1 - 0.0022 17.6 6.2 0.0022 17.6 6.2 2.4 1 1 1 2 2 2 1 PspA/IM30 family Spc7 PF08317.11 ORY00411.1 - 0.033 13.1 17.1 0.051 12.5 17.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 ORY00411.1 - 0.078 12.3 18.1 0.15 11.4 18.1 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 ORY00411.1 - 0.14 12.1 20.1 0.16 11.9 6.3 3.1 3 1 0 3 3 3 0 Prefoldin subunit TFR_dimer PF04253.15 ORY00411.1 - 0.43 10.7 3.0 0.78 9.9 0.9 2.3 3 0 0 3 3 2 0 Transferrin receptor-like dimerisation domain BLOC1_2 PF10046.9 ORY00411.1 - 0.43 10.9 11.1 4 7.8 9.5 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_C PF07195.12 ORY00411.1 - 0.51 9.7 6.9 1.1 8.7 1.2 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus HAUS6_N PF14661.6 ORY00411.1 - 0.63 9.6 10.6 0.98 9.0 10.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Syntaxin-6_N PF09177.11 ORY00411.1 - 1.3 9.6 6.9 5 7.7 6.7 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FapA PF03961.13 ORY00411.1 - 1.8 7.1 11.0 2.8 6.5 11.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A YlqD PF11068.8 ORY00411.1 - 2.6 8.4 14.1 5.4 7.4 13.7 1.6 1 1 0 1 1 1 0 YlqD protein TSC22 PF01166.18 ORY00411.1 - 2.8 8.3 8.5 2.5 8.5 2.0 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family FlxA PF14282.6 ORY00411.1 - 3 7.9 15.0 4.4 7.4 8.8 2.2 1 1 1 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.19 ORY00411.1 - 3.1 5.6 11.4 3.6 5.4 10.4 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CDC37_N PF03234.14 ORY00411.1 - 3.3 8.6 8.4 6.7 7.6 8.4 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ZapB PF06005.12 ORY00411.1 - 3.7 8.1 20.1 1.7 9.1 7.5 2.9 1 1 0 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 ORY00411.1 - 5.5 6.5 8.6 8.1 5.9 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 ORY00411.1 - 6 7.4 12.4 7 7.2 4.3 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 LemA PF04011.12 ORY00411.1 - 6.1 6.7 11.1 23 4.8 9.2 2.2 1 1 1 2 2 2 0 LemA family Swi5 PF07061.11 ORY00411.1 - 6.9 6.8 10.1 6.1 7.0 2.8 2.7 1 1 1 2 2 2 0 Swi5 Ribosomal_S28e PF01200.18 ORY00412.1 - 1.4e-33 114.7 1.2 1.6e-33 114.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORY00412.1 - 0.042 14.2 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORY00412.1 - 0.058 13.4 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Mito_carr PF00153.27 ORY00413.1 - 7.7e-68 224.5 1.1 3.1e-23 81.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.18 ORY00414.1 - 0.017 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Fe-S_biosyn PF01521.20 ORY00415.1 - 1.9e-14 53.8 0.0 2.1e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_1_2 PF00155.21 ORY00416.1 - 2.7e-72 244.0 0.0 3.1e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY00416.1 - 4.1e-06 26.0 0.0 8.7e-06 24.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY00416.1 - 0.0028 16.3 0.0 0.0044 15.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 ORY00416.1 - 0.0032 16.1 0.0 0.0057 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 ORY00416.1 - 0.025 13.9 0.1 0.054 12.8 0.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY00416.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase zf-C2H2 PF00096.26 ORY00417.1 - 3.2e-11 43.0 12.9 4.1e-06 26.9 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY00417.1 - 3.5e-11 43.0 12.9 1.8e-09 37.6 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY00417.1 - 1.7e-09 37.7 10.8 3.4e-05 24.3 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY00417.1 - 2.3e-05 24.5 1.8 0.087 13.1 1.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY00417.1 - 0.00017 21.5 4.0 0.0018 18.2 0.1 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY00417.1 - 0.00025 20.7 9.7 0.00097 18.8 0.4 2.5 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 ORY00417.1 - 0.00044 20.5 3.1 0.0061 16.8 0.4 2.0 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY00417.1 - 0.0065 16.8 0.7 0.23 11.9 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY00417.1 - 0.0075 16.6 2.3 0.008 16.4 2.3 1.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 ORY00417.1 - 0.016 14.8 0.8 0.38 10.4 0.0 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 ORY00417.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORY00417.1 - 0.018 15.4 0.8 1.6 9.1 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.14 ORY00417.1 - 0.034 14.1 0.3 0.087 12.8 0.4 1.7 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.15 ORY00417.1 - 0.036 14.1 3.9 0.81 9.8 3.9 2.1 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_9 PF16293.5 ORY00417.1 - 0.061 13.2 0.5 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 ORY00417.1 - 0.081 12.7 4.8 0.26 11.1 5.1 1.7 1 1 0 1 1 1 0 GAGA factor zf-C2HC_2 PF13913.6 ORY00417.1 - 0.12 12.3 8.0 0.28 11.1 1.5 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 ORY00417.1 - 0.13 12.9 2.7 0.36 11.5 0.2 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-AN1 PF01428.16 ORY00417.1 - 2.1 8.6 6.5 13 6.0 1.3 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger HSF_DNA-bind PF00447.17 ORY00418.1 - 3.3e-25 88.5 0.0 5.6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding ADH_zinc_N PF00107.26 ORY00419.1 - 6.5e-18 65.0 0.1 1.4e-17 63.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY00419.1 - 4e-17 63.5 0.0 6.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 ORY00419.1 - 1.2e-05 25.3 0.2 1.5e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DapB_N PF01113.20 ORY00419.1 - 0.0014 18.8 0.4 0.0038 17.3 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 ORY00419.1 - 0.007 16.8 0.2 0.028 14.9 0.1 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY00419.1 - 0.023 14.0 0.3 0.032 13.5 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DFP PF04127.15 ORY00419.1 - 0.028 14.2 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glu_synthase PF01645.17 ORY00419.1 - 0.033 13.3 0.2 0.046 12.8 0.2 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase 2-Hacid_dh_C PF02826.19 ORY00419.1 - 0.044 13.2 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORY00419.1 - 0.067 12.9 1.1 0.2 11.3 0.8 1.7 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.6 ORY00419.1 - 0.078 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_3 PF03447.16 ORY00419.1 - 0.11 13.2 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 ORY00419.1 - 0.11 12.3 0.3 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 ORY00419.1 - 0.12 11.8 1.1 0.2 11.1 1.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase PGM_PMM_II PF02879.16 ORY00419.1 - 0.12 13.0 0.0 0.38 11.4 0.0 1.8 2 0 0 2 2 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DHFR_1 PF00186.19 ORY00420.1 - 1.1e-37 129.2 0.0 1.8e-37 128.5 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase PA PF02225.22 ORY00421.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 PA domain Rsa3 PF14615.6 ORY00422.1 - 0.19 11.4 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Sel1 PF08238.12 ORY00423.1 - 5.3e-128 414.6 54.7 4.7e-10 39.8 0.4 14.6 15 0 0 15 15 15 14 Sel1 repeat TPR_16 PF13432.6 ORY00423.1 - 0.016 15.8 25.1 2.3 8.9 0.0 7.6 7 2 2 9 9 9 0 Tetratricopeptide repeat pP_pnuc_1 PF18165.1 ORY00423.1 - 0.05 13.5 1.3 56 3.6 0.1 4.8 4 2 2 6 6 6 0 Predicted pPIWI-associating nuclease TEX29 PF15839.5 ORY00423.1 - 0.26 11.9 2.8 31 5.3 0.0 5.4 7 1 1 8 8 8 0 Testis-expressed sequence 29 protein zf-MYND PF01753.18 ORY00424.1 - 4e-08 33.2 13.1 7.6e-08 32.3 13.1 1.5 1 0 0 1 1 1 1 MYND finger DUF5320 PF17253.2 ORY00426.1 - 0.25 12.4 7.3 1.1 10.3 7.3 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Thioredoxin PF00085.20 ORY00427.1 - 2.6e-67 223.3 6.8 1.2e-33 115.2 0.1 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 ORY00427.1 - 3.8e-50 170.4 6.0 1.1e-39 136.3 0.9 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 ORY00427.1 - 2.4e-15 56.5 10.5 5e-14 52.1 4.8 2.7 2 1 1 3 3 3 2 Calsequestrin OST3_OST6 PF04756.13 ORY00427.1 - 8.1e-11 41.8 0.8 7.4e-05 22.2 0.1 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY00427.1 - 3.7e-10 40.2 2.6 0.00086 19.7 0.1 3.4 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY00427.1 - 2.1e-09 37.6 1.4 0.071 13.4 0.0 5.4 4 2 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY00427.1 - 3.8e-08 33.4 0.1 0.019 15.1 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 ORY00427.1 - 2.5e-07 30.7 1.4 0.015 15.2 0.1 3.4 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.13 ORY00427.1 - 6.9e-06 26.2 1.0 0.064 13.4 0.0 4.1 3 1 0 3 3 3 2 ERp29, N-terminal domain Redoxin PF08534.10 ORY00427.1 - 3.1e-05 23.7 1.2 0.11 12.2 0.0 3.4 3 0 0 3 3 3 2 Redoxin Glutaredoxin PF00462.24 ORY00427.1 - 0.01 16.0 3.4 6.6 7.0 0.0 4.0 3 1 0 3 3 3 0 Glutaredoxin TraF PF13728.6 ORY00427.1 - 0.011 15.6 0.0 0.36 10.6 0.0 2.8 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 ORY00427.1 - 0.031 14.4 2.2 7.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin EF-hand_6 PF13405.6 ORY00427.1 - 0.042 13.8 0.8 0.48 10.5 0.4 2.9 2 1 0 2 2 2 0 EF-hand domain Thioredoxin_3 PF13192.6 ORY00427.1 - 1.3 9.1 4.5 2.1 8.4 0.1 3.3 4 0 0 4 4 4 0 Thioredoxin domain Thioredoxin PF00085.20 ORY00428.1 - 3.9e-06 26.8 0.0 6.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF5334 PF17268.2 ORY00428.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5334) zf-C2H2 PF00096.26 ORY00429.1 - 1.1e-12 47.6 12.4 6.8e-07 29.4 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY00429.1 - 1.5e-09 37.8 1.2 1.5e-09 37.8 1.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY00429.1 - 2e-09 37.5 10.1 0.00029 21.4 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY00429.1 - 0.00051 20.0 7.3 0.21 11.6 2.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY00429.1 - 0.0022 18.2 1.9 1.4 9.3 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY00429.1 - 0.0034 17.1 11.0 0.12 12.2 1.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.7 ORY00429.1 - 0.0084 16.5 2.4 2.1 8.9 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 ORY00429.1 - 0.0084 16.3 2.2 0.01 16.0 2.2 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_11 PF16622.5 ORY00429.1 - 0.2 11.4 5.9 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 ORY00429.1 - 1.4 8.6 4.8 1 9.0 1.2 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain STE PF02200.16 ORY00430.1 - 1.1e-55 186.8 0.1 1.2e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 STE like transcription factor Arrestin_C PF02752.22 ORY00431.1 - 6.8e-16 58.9 0.2 8.3e-14 52.2 0.2 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY00431.1 - 2e-10 40.9 0.1 5.5e-09 36.2 0.1 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY00431.1 - 0.0066 16.2 0.1 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Snf7 PF03357.21 ORY00432.1 - 6.1e-23 81.3 13.7 1.1e-22 80.5 13.7 1.4 1 0 0 1 1 1 1 Snf7 Melibiase_2_C PF17450.2 ORY00432.1 - 0.08 13.2 0.0 0.29 11.4 0.0 2.0 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain YtxH PF12732.7 ORY00432.1 - 1.3 9.6 5.0 9.4 6.8 2.6 3.2 2 1 0 2 2 2 0 YtxH-like protein LMBR1 PF04791.16 ORY00433.1 - 3.1e-16 59.4 18.8 3.2e-11 42.9 11.6 2.4 2 1 0 2 2 2 2 LMBR1-like membrane protein PH_12 PF16457.5 ORY00434.1 - 4.5e-34 117.9 0.0 9e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 ORY00434.1 - 1.7e-26 93.0 0.5 3.6e-26 91.9 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 ORY00434.1 - 3.8e-26 92.3 0.0 7.9e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family SFTA2 PF15210.6 ORY00434.1 - 0.11 12.5 0.2 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Surfactant-associated protein 2 V-SNARE PF05008.15 ORY00435.1 - 2.7e-21 75.7 4.3 2.7e-21 75.7 4.3 2.5 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORY00435.1 - 3.2e-17 62.6 4.3 3.2e-17 62.6 4.3 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus HBM PF16591.5 ORY00435.1 - 0.0019 17.7 1.7 0.0019 17.7 1.7 2.1 1 1 1 2 2 2 1 Helical bimodular sensor domain Laminin_I PF06008.14 ORY00435.1 - 0.0039 16.9 10.2 0.039 13.7 3.5 2.2 2 0 0 2 2 2 2 Laminin Domain I DUF2730 PF10805.8 ORY00435.1 - 0.015 15.4 2.8 0.047 13.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DLP_helical PF18709.1 ORY00435.1 - 0.017 14.3 3.4 0.021 14.0 1.0 1.9 2 0 0 2 2 2 0 Dynamin-like helical domain ZnuA PF01297.17 ORY00435.1 - 0.018 14.5 0.2 0.036 13.5 0.2 1.5 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DUF668 PF05003.12 ORY00435.1 - 0.02 15.4 1.0 0.052 14.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF668) HTH_WhiA PF02650.14 ORY00435.1 - 0.092 13.1 4.0 0.084 13.2 2.4 1.7 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Prominin PF05478.11 ORY00435.1 - 0.28 9.1 1.3 0.28 9.1 1.3 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 ORY00435.1 - 0.32 10.5 9.8 0.76 9.3 9.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Pepsin-I3 PF06394.13 ORY00435.1 - 0.41 10.9 2.0 1.5 9.1 0.4 2.5 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF745 PF05335.13 ORY00435.1 - 0.64 9.7 5.1 0.68 9.6 3.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.22 ORY00435.1 - 0.74 10.1 6.2 3.1 8.1 1.2 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 ORY00435.1 - 1.3 7.6 4.3 1.8 7.0 3.9 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 ORY00435.1 - 5.5 8.0 13.9 0.38 11.7 4.7 2.8 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain OmpH PF03938.14 ORY00435.1 - 9.5 6.6 10.3 8.8 6.7 8.0 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Caleosin PF05042.13 ORY00436.1 - 3.8e-61 205.9 0.1 4.5e-61 205.7 0.1 1.0 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 ORY00436.1 - 2.1e-06 27.2 0.7 0.008 16.0 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY00436.1 - 2.1e-05 23.7 0.7 0.018 14.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 ORY00436.1 - 9.1e-05 22.2 0.2 0.47 10.3 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 ORY00436.1 - 0.005 17.3 0.4 0.069 13.6 0.2 2.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY00436.1 - 0.029 13.9 1.0 3.2 7.4 0.2 2.6 2 0 0 2 2 2 0 EF hand Ank_4 PF13637.6 ORY00437.1 - 3.2e-16 59.5 0.8 1.9e-08 34.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY00437.1 - 2.8e-13 48.7 1.1 1.8e-06 27.8 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY00437.1 - 6e-13 49.2 0.1 6.9e-09 36.2 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY00437.1 - 9e-10 38.6 5.2 6.6e-06 26.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY00437.1 - 3.7e-08 33.5 0.6 0.00037 20.7 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Lactamase_B PF00753.27 ORY00438.1 - 3.8e-16 59.7 0.0 1.3e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY00438.1 - 0.00029 20.4 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain T3RM_EcoP15I_C PF18273.1 ORY00438.1 - 0.095 13.0 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain ADH_N PF08240.12 ORY00439.1 - 8.1e-20 70.7 3.1 1.3e-19 70.0 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY00439.1 - 2.5e-11 43.7 0.1 4.5e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY00439.1 - 0.012 15.5 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 ORY00439.1 - 0.041 13.2 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY00439.1 - 0.18 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Questin_oxidase PF14027.6 ORY00471.1 - 2.1e-63 214.9 0.0 2.5e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF5463 PF17551.2 ORY00471.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) Response_reg PF00072.24 ORY00472.1 - 2.4e-09 37.3 0.0 0.0013 18.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain RRM_1 PF00076.22 ORY00474.1 - 2.1e-15 56.3 0.0 2.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY00474.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY00474.1 - 0.049 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif TPR_1 PF00515.28 ORY00475.1 - 3e-11 42.6 0.1 0.0047 16.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY00475.1 - 1.3e-06 28.0 0.4 0.092 12.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 ORY00475.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_8 PF13181.6 ORY00475.1 - 0.0001 22.2 0.4 1.4 9.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 ORY00475.1 - 0.0047 17.0 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.6 ORY00475.1 - 0.01 16.1 0.0 0.64 10.4 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY00475.1 - 0.032 13.9 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 TPR repeat UBA_4 PF14555.6 ORY00475.1 - 0.081 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain PSP1 PF04468.12 ORY00477.1 - 1.2e-34 118.5 2.7 1.8e-34 117.8 2.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Yae1_N PF09811.9 ORY00479.1 - 9.6e-07 28.4 3.9 1.4e-06 27.9 3.9 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CAF-1_p150 PF11600.8 ORY00479.1 - 0.0016 18.1 1.9 0.003 17.3 1.9 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SKIP_SNW PF02731.15 ORY00480.1 - 9.2e-73 243.2 6.4 9.2e-73 243.2 6.4 2.1 2 0 0 2 2 2 1 SKIP/SNW domain F5_F8_type_C PF00754.25 ORY00480.1 - 0.044 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 F5/8 type C domain SGL PF08450.12 ORY00481.1 - 2.1e-30 106.1 0.1 5.2e-29 101.6 0.1 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 ORY00481.1 - 0.0013 18.7 0.2 16 5.6 0.0 4.1 3 1 0 3 3 3 1 Beta-propeller repeat NHL PF01436.21 ORY00481.1 - 0.0032 17.4 0.3 32 4.8 0.1 4.6 5 0 0 5 5 5 0 NHL repeat Phytase-like PF13449.6 ORY00481.1 - 0.0068 16.4 0.0 0.042 13.8 0.0 2.2 2 1 0 2 2 2 1 Esterase-like activity of phytase Lactonase PF10282.9 ORY00481.1 - 0.012 14.9 0.0 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SdiA-regulated PF06977.11 ORY00481.1 - 0.19 10.9 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated TMEM164 PF14808.6 ORY00482.1 - 3.5e-23 82.2 16.0 4.5e-23 81.9 16.0 1.1 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 ORY00482.1 - 3e-08 33.5 30.0 3.9e-08 33.1 30.0 1.1 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) Herpes_LMP1 PF05297.11 ORY00482.1 - 2.4 7.3 10.3 3.5 6.7 10.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Myb_DNA-bind_7 PF15963.5 ORY00483.1 - 1.6e-25 88.8 0.2 2.3e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORY00483.1 - 2.2e-11 43.7 0.0 3.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY00483.1 - 8.9e-06 25.9 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain NA37 PF04245.13 ORY00483.1 - 0.12 11.9 0.2 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein TRM PF02005.16 ORY00484.1 - 2.1e-132 441.9 0.0 2.6e-132 441.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 ORY00484.1 - 6.2e-07 29.4 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 ORY00484.1 - 0.033 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 ORY00484.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY00484.1 - 0.15 12.8 0.0 0.36 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cep3 PF16846.5 ORY00484.1 - 0.23 9.9 0.0 0.95 7.9 0.0 1.8 2 0 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B Guanylate_cyc_2 PF09778.9 ORY00485.1 - 1.2e-51 175.1 0.3 1.4e-51 174.9 0.3 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 ORY00485.1 - 0.042 14.4 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family Pox_A_type_inc PF04508.12 ORY00486.1 - 0.065 13.1 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat adh_short PF00106.25 ORY00487.1 - 7.6e-83 276.8 10.8 4.3e-46 156.8 1.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY00487.1 - 1.6e-67 227.5 6.6 1.6e-39 135.8 0.4 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 ORY00487.1 - 2e-31 108.1 0.0 5.7e-31 106.6 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 ORY00487.1 - 1e-30 107.0 5.8 4.4e-16 59.3 1.0 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 ORY00487.1 - 3.1e-09 37.1 0.0 5.2e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 ORY00487.1 - 0.0033 16.8 5.6 0.045 13.1 0.3 2.7 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 ORY00487.1 - 0.011 15.1 0.3 0.039 13.3 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PglL_A PF15864.5 ORY00487.1 - 0.14 11.9 3.6 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Epimerase PF01370.21 ORY00487.1 - 0.16 11.4 1.8 2.8 7.4 0.2 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORY00487.1 - 0.27 11.1 7.3 0.92 9.4 0.9 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 ORY00487.1 - 0.5 10.4 2.5 12 5.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Bromodomain PF00439.25 ORY00488.1 - 1.8e-134 438.1 4.9 6.9e-22 77.3 0.0 6.6 6 0 0 6 6 6 6 Bromodomain Ras PF00071.22 ORY00488.1 - 2.4e-39 134.6 0.0 4.7e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY00488.1 - 6.4e-12 45.7 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Peptidase_M1 PF01433.20 ORY00488.1 - 0.00096 18.8 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain HEAT_2 PF13646.6 ORY00488.1 - 0.075 13.4 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats U79_P34 PF03064.16 ORY00488.1 - 7.2 5.9 10.7 23 4.2 10.7 1.8 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PWWP PF00855.17 ORY00489.1 - 5.8e-22 77.9 1.0 5.8e-22 77.9 1.0 2.7 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 ORY00489.1 - 4e-05 23.5 0.1 0.00013 21.9 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Spectrin PF00435.21 ORY00489.1 - 0.15 12.5 13.4 0.12 12.8 0.6 4.0 3 1 0 3 3 3 0 Spectrin repeat Ribosomal_L38e PF01781.18 ORY00490.1 - 1.3e-35 121.3 1.7 1.4e-35 121.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORY00490.1 - 0.066 13.4 0.0 0.076 13.2 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORY00490.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Lyase_1 PF00206.20 ORY00491.1 - 3.5e-21 75.9 0.0 5.4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY00491.1 - 7e-17 61.7 0.0 2.3e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.25 ORY00492.1 - 2.4e-65 220.5 0.0 4.1e-65 219.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00492.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00492.1 - 5.1e-10 39.1 0.0 7.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY00492.1 - 0.00045 19.6 0.2 0.001 18.5 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY00492.1 - 0.00071 18.5 0.0 0.0015 17.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY00492.1 - 0.0012 18.8 0.1 0.0019 18.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY00492.1 - 0.0027 16.7 0.1 0.0034 16.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 ORY00492.1 - 0.093 11.7 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tup_N PF08581.10 ORY00493.1 - 0.26 11.6 3.0 0.4 11.0 3.0 1.3 1 0 0 1 1 1 0 Tup N-terminal SCO1-SenC PF02630.14 ORY00494.1 - 1.4e-50 170.6 0.0 2.4e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ORY00494.1 - 3.1e-05 23.9 0.1 6.4e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ORY00494.1 - 0.00065 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Put_Phosphatase PF06888.12 ORY00495.1 - 1.1e-54 185.3 0.1 1.3e-54 185.1 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 ORY00495.1 - 3.7e-07 30.7 0.0 1.2e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 ORY00496.1 - 6.4e-20 70.8 3.2 6.9e-20 70.6 3.2 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY00496.1 - 0.0025 17.7 0.2 0.0036 17.2 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain 3HCDH_N PF02737.18 ORY00497.1 - 1.7e-63 213.8 0.6 2.6e-63 213.2 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY00497.1 - 1.2e-34 118.7 0.0 3.8e-34 117.2 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORY00497.1 - 0.00025 21.2 1.9 0.0021 18.2 1.9 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 ORY00497.1 - 0.0014 18.4 0.7 0.0031 17.3 0.3 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein UDPG_MGDP_dh_N PF03721.14 ORY00497.1 - 0.0021 17.7 0.2 0.0043 16.6 0.2 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY00497.1 - 0.0022 18.0 0.4 0.0072 16.3 0.4 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.6 ORY00497.1 - 0.0029 17.2 0.2 0.0045 16.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 ORY00497.1 - 0.004 16.4 0.3 0.0062 15.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ORY00497.1 - 0.0048 16.3 0.2 0.0088 15.4 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY00497.1 - 0.024 14.0 0.7 0.033 13.5 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 ORY00497.1 - 0.036 14.6 1.6 0.13 12.9 1.6 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ORY00497.1 - 0.044 13.2 0.1 0.068 12.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CRAL_TRIO PF00650.20 ORY00499.1 - 1.5e-34 119.0 0.1 2.1e-34 118.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY00499.1 - 4.3e-06 26.8 0.1 8.7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RhoGEF PF00621.20 ORY00499.1 - 0.048 13.9 0.6 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 RhoGEF domain TBD PF12845.7 ORY00499.1 - 0.14 12.1 0.3 5.8 6.9 0.0 2.6 2 0 0 2 2 2 0 TBD domain Glyco_transf_8 PF01501.20 ORY00500.1 - 1.1e-19 71.0 2.4 1.6e-19 70.5 2.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORY00500.1 - 1.1e-06 28.2 0.1 2.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative zf-C2H2 PF00096.26 ORY00501.1 - 3.5e-14 52.3 12.4 3.4e-07 30.4 4.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY00501.1 - 8.5e-11 41.8 15.5 1.9e-08 34.4 1.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY00501.1 - 1e-10 41.5 10.5 3.8e-05 24.2 2.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY00501.1 - 8.3e-06 26.0 2.6 0.006 16.8 0.4 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY00501.1 - 0.00028 21.2 4.0 0.0027 18.0 1.0 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY00501.1 - 0.00041 20.3 9.7 0.021 14.8 2.9 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY00501.1 - 0.0044 17.3 2.5 0.011 16.0 2.5 1.6 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 ORY00501.1 - 0.0079 16.5 1.8 0.012 15.9 1.8 1.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 ORY00501.1 - 0.017 15.0 5.1 0.82 9.6 1.1 2.6 2 2 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 ORY00501.1 - 0.018 14.6 3.3 0.082 12.6 1.1 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Zn-C2H2_12 PF18112.1 ORY00501.1 - 0.041 14.4 4.1 3.8 8.1 0.0 3.0 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_ZIC PF18366.1 ORY00501.1 - 0.045 13.9 1.4 2.5 8.3 0.0 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain Ogr_Delta PF04606.12 ORY00501.1 - 0.065 13.2 4.3 0.72 9.9 0.3 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_2 PF12756.7 ORY00501.1 - 0.14 12.5 3.3 0.85 10.0 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF448 PF04296.13 ORY00501.1 - 0.26 11.2 1.9 2.2 8.2 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF448) zf-C2HE PF16278.5 ORY00501.1 - 0.43 11.1 3.2 1.2 9.6 0.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ORY00501.1 - 0.59 10.1 5.8 3.1 7.8 0.1 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Pkinase PF00069.25 ORY00502.1 - 5.7e-56 189.8 0.1 9.4e-56 189.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00502.1 - 4.2e-40 137.7 0.0 6.1e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 ORY00502.1 - 0.00043 20.4 0.1 0.00096 19.3 0.1 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 ORY00502.1 - 0.013 14.3 0.1 0.034 12.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Carb_kinase PF01256.17 ORY00503.1 - 5.8e-52 176.6 0.0 6.9e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 ORY00503.1 - 4.4e-06 26.3 0.0 1.8e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase RAP1 PF07218.11 ORY00504.1 - 0.35 9.1 4.3 0.42 8.8 4.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S21e PF01249.18 ORY00505.1 - 3.2e-40 136.1 0.0 3.6e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4325 PF14213.6 ORY00505.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Sec2p PF06428.11 ORY00506.1 - 9.2e-18 64.0 13.6 9.2e-18 64.0 13.6 3.0 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p DUF4718 PF15842.5 ORY00506.1 - 0.011 15.5 0.3 0.026 14.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF3394 PF11874.8 ORY00506.1 - 0.41 10.3 2.2 1.1 9.0 1.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3394) zf-RING_UBOX PF13445.6 ORY00507.1 - 2.2e-07 30.8 7.6 5.5e-07 29.5 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY00507.1 - 5.5e-07 29.3 6.8 5.5e-07 29.3 6.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY00507.1 - 1.7e-06 27.8 4.9 1.7e-06 27.8 4.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY00507.1 - 2.8e-06 27.4 5.7 2.8e-06 27.4 5.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY00507.1 - 0.00012 22.0 7.4 0.00012 22.0 7.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY00507.1 - 0.00029 21.1 5.9 0.00029 21.1 5.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY00507.1 - 0.0015 18.3 4.7 0.0015 18.3 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY00507.1 - 0.078 12.7 6.9 0.17 11.6 6.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 ORY00507.1 - 0.09 12.7 0.8 0.23 11.4 0.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 ORY00507.1 - 0.13 12.4 4.2 0.15 12.2 2.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.6 ORY00507.1 - 1.2 9.0 11.7 2 8.3 5.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 ORY00508.1 - 7.3e-53 179.6 0.0 9.8e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00508.1 - 5.1e-27 94.8 0.0 7.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY00508.1 - 3.8e-06 26.4 0.0 5.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY00508.1 - 0.00042 20.0 0.1 0.0009 18.9 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 ORY00508.1 - 0.00068 19.0 0.0 0.0024 17.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY00508.1 - 0.001 19.1 0.0 0.0044 17.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY00508.1 - 0.0032 16.3 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY00508.1 - 0.011 14.8 0.4 0.11 11.5 0.1 2.0 1 1 1 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 ORY00508.1 - 0.028 14.0 0.2 0.89 9.1 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 ORY00508.1 - 0.058 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Hpt PF01627.23 ORY00509.1 - 4.9e-11 42.7 0.1 6.7e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Hpt domain CCDC32 PF14989.6 ORY00510.1 - 3.4e-05 23.9 3.6 4.5e-05 23.5 3.6 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing 32 CENP-F_leu_zip PF10473.9 ORY00510.1 - 6.1e-05 23.1 11.8 8.3e-05 22.6 11.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-F_N PF10481.9 ORY00510.1 - 0.00046 19.9 5.7 0.00052 19.7 5.7 1.1 1 0 0 1 1 1 1 Cenp-F N-terminal domain Filament PF00038.21 ORY00510.1 - 0.0033 17.1 7.1 0.0071 16.0 7.0 1.5 1 1 1 2 2 2 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 ORY00510.1 - 0.0034 17.5 6.1 0.005 16.9 6.1 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 ORY00510.1 - 0.0039 17.0 3.0 0.033 14.1 0.2 2.6 2 1 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor 5_nucleotid PF05761.14 ORY00510.1 - 0.0046 15.9 2.1 0.0056 15.7 2.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family Rx_N PF18052.1 ORY00510.1 - 0.0053 17.0 0.6 0.013 15.7 0.2 1.8 1 1 1 2 2 2 1 Rx N-terminal domain SKA2 PF16740.5 ORY00510.1 - 0.0097 15.7 3.8 0.01 15.6 1.9 1.9 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF812 PF05667.11 ORY00510.1 - 0.0099 14.8 6.9 0.012 14.5 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 ORY00510.1 - 0.013 15.0 3.9 0.019 14.4 3.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3450 PF11932.8 ORY00510.1 - 0.014 14.7 2.8 0.017 14.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SHE3 PF17078.5 ORY00510.1 - 0.014 15.1 8.1 0.027 14.2 8.1 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 OmpH PF03938.14 ORY00510.1 - 0.016 15.5 3.4 0.022 15.1 3.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IFT57 PF10498.9 ORY00510.1 - 0.016 14.2 5.9 0.021 13.8 5.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Enkurin PF13864.6 ORY00510.1 - 0.018 15.5 4.8 1.9 9.0 4.7 2.4 1 1 1 2 2 2 0 Calmodulin-binding YkyA PF10368.9 ORY00510.1 - 0.032 13.9 7.6 0.04 13.6 7.6 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein NPV_P10 PF05531.12 ORY00510.1 - 0.032 14.7 2.6 0.29 11.6 1.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 ORY00510.1 - 0.036 13.4 1.3 0.04 13.3 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 ORY00510.1 - 0.042 14.3 7.0 0.063 13.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IFT20 PF14931.6 ORY00510.1 - 0.044 13.9 7.3 0.068 13.3 7.3 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 BRE1 PF08647.11 ORY00510.1 - 0.054 13.6 14.6 1 9.5 8.5 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Mto2_bdg PF12808.7 ORY00510.1 - 0.067 13.5 0.6 0.067 13.5 0.6 2.1 3 0 0 3 3 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cep57_CLD_2 PF14197.6 ORY00510.1 - 0.067 13.3 6.4 0.71 10.0 0.7 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMPIT PF07851.13 ORY00510.1 - 0.07 12.4 5.3 0.087 12.1 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 ORY00510.1 - 0.1 12.1 3.3 0.13 11.8 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec34 PF04136.15 ORY00510.1 - 0.13 12.2 6.3 0.11 12.4 2.0 2.3 1 1 1 2 2 2 0 Sec34-like family Fer4_14 PF13394.6 ORY00510.1 - 0.13 12.4 1.2 0.36 11.0 0.3 2.0 1 1 1 2 2 2 0 4Fe-4S single cluster domain Rootletin PF15035.6 ORY00510.1 - 0.14 12.2 7.4 0.55 10.2 8.1 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.8 ORY00510.1 - 0.2 11.9 10.5 1.3 9.3 8.3 2.4 1 1 2 3 3 2 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 ORY00510.1 - 0.23 11.9 8.2 0.46 10.9 8.2 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 ORY00510.1 - 0.24 11.4 5.6 1.6 8.8 1.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DegS PF05384.11 ORY00510.1 - 0.25 10.8 7.9 1.9 7.9 1.3 2.2 1 1 1 2 2 2 0 Sensor protein DegS HAUS6_N PF14661.6 ORY00510.1 - 0.32 10.6 5.7 14 5.1 5.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF948 PF06103.11 ORY00510.1 - 0.37 11.1 2.9 5.3 7.4 1.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) K-box PF01486.17 ORY00510.1 - 0.54 10.5 9.1 0.27 11.4 2.1 2.6 1 1 1 2 2 2 0 K-box region HIP1_clath_bdg PF16515.5 ORY00510.1 - 0.65 10.6 8.3 6.7 7.4 8.9 2.0 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 ORY00510.1 - 0.76 10.3 8.7 1.3 9.6 8.7 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 ORY00510.1 - 0.83 10.1 12.1 6.2 7.3 3.8 3.1 1 1 2 3 3 3 0 Snapin/Pallidin Prefoldin_2 PF01920.20 ORY00510.1 - 1.3 9.0 11.2 4.3 7.3 1.6 2.5 1 1 1 2 2 2 0 Prefoldin subunit YabA PF06156.13 ORY00510.1 - 1.4 9.6 8.1 13 6.5 8.1 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 ORY00510.1 - 1.7 8.2 5.8 4.5 6.8 4.6 2.0 1 1 1 2 2 2 0 fzo-like conserved region KIAA1430 PF13879.6 ORY00510.1 - 1.9 9.3 10.3 3 8.7 10.3 1.4 1 1 0 1 1 1 0 KIAA1430 homologue DivIC PF04977.15 ORY00510.1 - 1.9 8.3 6.3 0.76 9.6 1.0 2.8 2 1 1 3 3 2 0 Septum formation initiator CCDC-167 PF15188.6 ORY00510.1 - 2.1 8.7 8.0 63 4.0 8.3 2.4 2 1 0 2 2 1 0 Coiled-coil domain-containing protein 167 Spc24 PF08286.11 ORY00510.1 - 2.9 8.2 9.6 2.3 8.5 2.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.21 ORY00510.1 - 4.6 7.4 11.4 11 6.3 8.1 3.1 1 1 1 2 2 2 0 bZIP transcription factor HR1 PF02185.16 ORY00510.1 - 7 6.8 11.7 2 8.6 1.1 3.2 1 1 2 3 3 3 0 Hr1 repeat NPR2 PF06218.11 ORY00511.1 - 2.9e-119 398.7 5.7 2.2e-94 316.7 5.7 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 ORY00511.1 - 9.3e-05 21.4 0.1 0.37 9.5 0.0 3.1 2 1 1 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 TSCPD PF12637.7 ORY00511.1 - 0.16 12.2 0.0 0.72 10.1 0.0 2.1 2 0 0 2 2 2 0 TSCPD domain zf-C2H2 PF00096.26 ORY00512.1 - 1.1e-12 47.7 9.6 2.4e-06 27.7 2.3 2.5 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY00512.1 - 1.8e-10 40.8 7.6 1.5e-05 25.5 2.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY00512.1 - 1.1e-09 38.2 6.3 1.8e-05 24.9 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORY00512.1 - 9.1e-09 35.4 1.4 3.1e-05 24.2 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY00512.1 - 1.1e-07 31.7 4.5 1.1e-05 25.3 0.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY00512.1 - 4.1e-07 30.1 3.3 0.00016 21.8 0.3 2.4 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ORY00512.1 - 0.00096 19.1 7.0 0.016 15.2 0.9 2.2 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 ORY00512.1 - 0.004 17.4 2.1 0.078 13.3 0.3 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORY00512.1 - 0.037 13.8 9.1 0.4 10.5 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 ORY00512.1 - 0.042 14.1 1.5 0.58 10.5 0.2 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 ORY00512.1 - 0.078 13.3 1.8 5.6 7.3 0.1 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 ORY00512.1 - 0.12 12.0 0.8 1.5 8.5 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 ORY00512.1 - 0.18 11.6 5.9 3.4 7.5 0.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type FYVE PF01363.21 ORY00512.1 - 1.2 9.3 6.3 1.3 9.2 1.0 2.0 1 1 0 2 2 2 0 FYVE zinc finger Palm_thioest PF02089.15 ORY00513.1 - 5.8e-08 32.9 0.0 1.5e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 ORY00513.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY00513.1 - 9.7e-06 25.4 0.1 0.00035 20.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 ORY00513.1 - 0.00029 20.4 0.0 0.00045 19.8 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 ORY00513.1 - 0.00033 19.9 0.0 0.00048 19.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ORY00513.1 - 0.0014 19.3 0.1 0.0019 18.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY00513.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Sugar_tr PF00083.24 ORY00514.1 - 7.4e-133 443.7 28.1 8.4e-133 443.5 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY00514.1 - 2.7e-32 112.1 60.1 1.4e-26 93.3 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5134 PF17197.4 ORY00514.1 - 0.066 13.1 2.3 0.3 11.0 2.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Pyr_redox_2 PF07992.14 ORY00515.1 - 2.1e-33 115.9 0.1 2.5e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY00515.1 - 1.9e-15 57.2 2.0 9.1e-12 45.4 0.6 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY00515.1 - 3.2e-10 40.1 0.1 0.0043 16.7 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY00515.1 - 6.7e-10 38.7 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY00515.1 - 2.8e-09 36.6 0.4 2.1e-07 30.5 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY00515.1 - 9.4e-08 32.2 0.4 0.036 14.1 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY00515.1 - 6.4e-05 23.1 0.0 0.031 14.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY00515.1 - 0.00028 20.1 0.5 0.16 11.0 0.2 2.9 2 1 1 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.17 ORY00515.1 - 0.0015 17.8 0.0 0.21 10.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family RNaseH_C PF09293.10 ORY00515.1 - 0.0083 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 T4 RNase H, C terminal HI0933_like PF03486.14 ORY00515.1 - 0.018 13.7 1.6 0.69 8.6 0.1 3.1 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 ORY00515.1 - 0.03 13.6 0.0 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 ORY00515.1 - 0.056 13.7 0.3 5.5 7.3 0.1 2.9 2 0 0 2 2 2 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ORY00515.1 - 0.1 12.8 0.2 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ferritin PF00210.24 ORY00516.1 - 7.5e-40 136.1 0.1 8.6e-40 135.9 0.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ORY00516.1 - 5.7e-06 26.8 0.1 7.1e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Rubrerythrin PPV_E2_N PF00508.17 ORY00516.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal Bac_globin PF01152.21 ORY00517.1 - 5.7e-11 42.6 0.1 6.9e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORY00517.1 - 0.003 17.5 0.1 0.0042 17.0 0.1 1.5 1 1 0 1 1 1 1 Protoglobin Peptidase_M16_C PF05193.21 ORY00517.1 - 0.056 13.5 0.0 0.22 11.5 0.0 1.7 1 1 1 2 2 2 0 Peptidase M16 inactive domain HMG_box PF00505.19 ORY00518.1 - 1.6e-21 76.5 1.3 1.8e-21 76.3 1.3 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY00518.1 - 1.1e-09 38.7 0.9 1.2e-09 38.6 0.9 1.0 1 0 0 1 1 1 1 HMG-box domain KORA PF16509.5 ORY00518.1 - 0.033 14.5 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor DUF3268 PF11672.8 ORY00518.1 - 0.047 14.0 0.1 0.053 13.8 0.1 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain Iso_dh PF00180.20 ORY00519.1 - 7.1e-79 265.5 0.0 8.8e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ANTH PF07651.16 ORY00520.1 - 3.6e-69 232.8 0.0 3.6e-69 232.8 0.0 2.9 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 ORY00520.1 - 7.1e-45 153.0 11.3 7.1e-45 153.0 11.3 6.5 3 2 3 7 7 7 2 I/LWEQ domain TcdB_N PF12918.7 ORY00520.1 - 0.072 13.4 0.4 0.072 13.4 0.4 3.0 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain HMG_box PF00505.19 ORY00521.1 - 6.1e-25 87.4 2.0 6.7e-25 87.3 2.0 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY00521.1 - 2.1e-12 47.4 0.9 2.3e-12 47.3 0.9 1.0 1 0 0 1 1 1 1 HMG-box domain HTH_24 PF13412.6 ORY00521.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ntox43 PF15537.6 ORY00521.1 - 0.042 13.9 0.0 0.088 12.9 0.0 1.5 1 1 1 2 2 2 0 Bacterial toxin 43 Protamine_like PF06382.11 ORY00521.1 - 0.058 13.6 0.0 0.067 13.4 0.0 1.1 1 0 0 1 1 1 0 Protamine and protamine like RRM_1 PF00076.22 ORY00523.1 - 3.7e-15 55.5 0.0 5.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 ORY00523.1 - 1.7e-14 53.1 15.5 4.2e-08 32.9 2.8 3.0 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_5 PF14787.6 ORY00523.1 - 0.00014 21.5 12.1 0.016 14.9 2.2 2.5 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ORY00523.1 - 0.00036 20.3 9.6 0.00046 19.9 1.9 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 ORY00523.1 - 0.00095 18.9 6.6 0.28 10.9 1.2 2.4 2 0 0 2 2 2 2 Zinc knuckle RRM_5 PF13893.6 ORY00523.1 - 0.0018 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ORY00523.1 - 0.0021 18.0 0.1 0.0031 17.5 0.1 1.2 1 0 0 1 1 1 1 DbpA RNA binding domain zf-CCHC_3 PF13917.6 ORY00523.1 - 0.012 15.5 10.6 0.044 13.7 0.5 2.5 1 1 1 2 2 2 0 Zinc knuckle RRM_occluded PF16842.5 ORY00523.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY00523.1 - 0.096 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 ORY00523.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ntox16 PF15523.6 ORY00523.1 - 0.57 10.4 5.2 6.6 7.0 0.7 2.2 2 0 0 2 2 2 0 Novel toxin 16 zf-CCHC_6 PF15288.6 ORY00523.1 - 0.94 9.4 9.8 4.1 7.3 1.9 2.4 2 0 0 2 2 2 0 Zinc knuckle PSS PF03034.15 ORY00524.1 - 3.2e-118 394.4 19.8 4.3e-118 394.0 19.8 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Glycoprotein PF03409.15 ORY00524.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein Ribosomal_S19 PF00203.21 ORY00525.1 - 1.5e-36 124.1 1.0 2.1e-36 123.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 ORY00526.1 - 1.4e-26 92.8 14.0 1.6e-26 92.7 14.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rnk_N PF14760.6 ORY00526.1 - 0.55 10.8 0.4 0.55 10.8 0.4 2.6 3 1 0 3 3 3 0 Rnk N-terminus Nop52 PF05997.12 ORY00527.1 - 2.2e-73 246.6 3.0 2.2e-73 246.6 3.0 2.4 3 1 0 3 3 3 1 Nucleolar protein,Nop52 HEAT PF02985.22 ORY00527.1 - 0.096 13.0 0.0 0.95 9.9 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat DUF4667 PF15700.5 ORY00527.1 - 2.7 8.0 9.1 5.9 6.9 9.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) TAN PF11640.8 ORY00527.1 - 6.7 6.8 9.0 28 4.8 0.0 3.2 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Nuc_sug_transp PF04142.15 ORY00528.1 - 1.7e-108 362.5 18.5 2e-108 362.3 18.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORY00528.1 - 1.7e-07 30.7 16.5 2.7e-07 30.1 16.5 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.6 ORY00528.1 - 0.00013 21.7 4.3 0.0002 21.0 4.2 1.5 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter EamA PF00892.20 ORY00528.1 - 0.00067 19.8 29.0 0.00083 19.5 4.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORY00528.1 - 0.0035 16.6 19.2 0.0062 15.8 19.2 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 ORY00528.1 - 0.74 9.1 14.3 0.22 10.8 0.9 1.8 1 1 1 2 2 2 0 Triose-phosphate Transporter family Ribosomal_L26 PF16906.5 ORY00529.1 - 3e-37 127.0 4.0 3.8e-37 126.6 4.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY00529.1 - 5.3e-10 38.9 2.4 5.3e-10 38.9 2.4 1.7 2 0 0 2 2 2 1 KOW motif ChaC PF04752.12 ORY00530.1 - 1.1e-25 90.8 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein GIY-YIG PF01541.24 ORY00530.1 - 0.044 14.1 0.0 0.61 10.4 0.0 2.2 2 0 0 2 2 2 0 GIY-YIG catalytic domain NapB PF03892.14 ORY00530.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) SPT2 PF08243.11 ORY00531.1 - 4.1e-19 69.1 13.2 4.1e-19 69.1 13.2 3.5 2 1 0 3 3 3 1 SPT2 chromatin protein DUF5401 PF17380.2 ORY00531.1 - 0.81 7.7 39.8 0.083 11.0 18.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Pkinase PF00069.25 ORY00532.1 - 5.1e-54 183.4 0.0 8.3e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00532.1 - 1.3e-23 83.6 0.0 1.8e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 ORY00532.1 - 0.0019 17.9 0.0 0.066 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORY00532.1 - 0.0029 17.0 0.0 0.004 16.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY00532.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY00532.1 - 0.017 14.1 0.1 0.74 8.7 0.0 2.2 1 1 1 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 ORY00532.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_18 PF00704.28 ORY00557.1 - 1.2e-70 238.7 1.0 1.2e-70 238.7 1.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORY00557.1 - 0.00054 20.4 11.8 0.00054 20.4 11.8 4.1 3 0 0 3 3 3 1 Carbohydrate binding domain MGC-24 PF05283.11 ORY00557.1 - 9.9 6.6 10.0 19 5.7 10.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Crystall PF00030.19 ORY00559.1 - 0.063 13.5 0.9 0.28 11.4 0.9 1.9 1 1 0 1 1 1 0 Beta/Gamma crystallin Homeodomain PF00046.29 ORY00560.1 - 2.9e-15 55.8 4.7 3.1e-15 55.7 4.7 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY00560.1 - 0.005 16.7 0.1 0.008 16.1 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORY00560.1 - 0.041 13.7 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT PAS_3 PF08447.12 ORY00561.1 - 1.3e-16 60.6 0.0 8.3e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY00561.1 - 3.5e-09 36.8 0.0 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORY00561.1 - 5.1e-08 32.9 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORY00561.1 - 0.0015 18.8 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_12 PF18095.1 ORY00561.1 - 0.015 14.9 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain PAS_11 PF14598.6 ORY00561.1 - 0.066 13.3 0.0 2.1 8.5 0.0 2.3 2 1 0 2 2 2 0 PAS domain PAS_2 PF08446.11 ORY00561.1 - 0.066 13.9 0.0 2 9.1 0.0 2.3 2 0 0 2 2 2 0 PAS fold HIRAN PF08797.11 ORY00561.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 HIRAN domain MEKHLA PF08670.11 ORY00561.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 MEKHLA domain Cyclin PF08613.11 ORY00562.1 - 0.00027 21.4 0.1 0.0009 19.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY00562.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BNIP3 PF06553.12 ORY00562.1 - 0.0023 17.6 0.1 0.0027 17.4 0.1 1.2 1 0 0 1 1 1 1 BNIP3 Yae1_N PF09811.9 ORY00563.1 - 1.3e-12 47.2 22.7 1e-07 31.5 5.1 4.2 2 2 3 5 5 5 5 Essential protein Yae1, N terminal Keratin_2_head PF16208.5 ORY00563.1 - 1 9.5 11.1 10 6.2 11.1 2.1 1 1 0 1 1 1 0 Keratin type II head Yae1_N PF09811.9 ORY00564.1 - 2.4e-11 43.1 25.6 8.5e-07 28.6 5.5 4.2 2 2 2 4 4 4 4 Essential protein Yae1, N terminal RNase_T PF00929.24 ORY00565.1 - 2.4e-07 31.4 0.0 3.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ORY00565.1 - 0.093 12.7 0.0 0.49 10.4 0.0 2.0 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like SurE PF01975.17 ORY00566.1 - 2e-45 155.0 0.0 2.6e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE tRNA-synt_2b PF00587.25 ORY00567.1 - 4.8e-35 121.1 0.0 8.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY00567.1 - 5e-20 71.5 0.2 1.1e-19 70.3 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 ORY00567.1 - 2.1e-12 46.9 0.0 4.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 ORY00567.1 - 3.3e-11 43.1 0.0 7.2e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CDO_I PF05995.12 ORY00568.1 - 6.3e-51 172.0 0.2 8.5e-51 171.6 0.2 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ORY00568.1 - 2.2e-05 24.0 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 ORY00569.1 - 4.7e-51 172.4 0.1 5.9e-51 172.1 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ORY00569.1 - 3.1e-05 23.5 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO PAPA-1 PF04795.12 ORY00570.1 - 8.1e-22 77.8 6.8 1.2e-21 77.2 6.8 1.3 1 0 0 1 1 1 1 PAPA-1-like conserved region zf-HIT PF04438.16 ORY00570.1 - 0.017 15.0 0.4 0.028 14.3 0.4 1.3 1 0 0 1 1 1 0 HIT zinc finger DUF3298 PF11738.8 ORY00570.1 - 0.024 15.6 0.3 0.046 14.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) DUF5401 PF17380.2 ORY00570.1 - 9.2 4.2 14.6 11 3.9 14.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Med23 PF11573.8 ORY00571.1 - 1.4e-72 245.0 20.4 4.2e-68 230.2 13.9 3.1 2 1 0 2 2 2 2 Mediator complex subunit 23 Peptidase_M48 PF01435.18 ORY00572.1 - 3.2e-37 128.2 0.0 5.2e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 VHS PF00790.19 ORY00573.1 - 7.6e-42 142.5 6.6 1.8e-41 141.3 0.4 2.7 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 ORY00573.1 - 2.2e-17 63.0 10.2 4.1e-17 62.1 10.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ORY00573.1 - 1.6e-08 33.9 6.2 0.00012 21.7 1.1 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 ORY00573.1 - 2.5e-06 27.7 0.6 2.6e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 GAT domain Hrs_helical PF12210.8 ORY00573.1 - 4.7e-06 27.0 0.7 9e-06 26.1 0.2 1.7 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE_2 PF02318.16 ORY00573.1 - 0.0012 19.0 5.6 0.0027 17.9 5.6 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Luteo_P1-P2 PF08467.10 ORY00573.1 - 0.023 14.0 0.2 0.039 13.2 0.2 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase MMS19_N PF14500.6 ORY00573.1 - 0.075 12.6 0.9 4.5 6.8 0.1 2.7 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DZR PF12773.7 ORY00573.1 - 0.39 10.8 9.2 12 6.0 0.6 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-B_box PF00643.24 ORY00573.1 - 2.6 8.3 10.7 5.4 7.3 10.7 1.6 1 0 0 1 1 1 0 B-box zinc finger PBP PF01161.20 ORY00574.1 - 1.7e-16 60.7 0.0 3.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Spc24 PF08286.11 ORY00574.1 - 0.035 14.3 0.1 0.15 12.3 0.2 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PAF PF15715.5 ORY00575.1 - 0.076 13.6 0.3 0.088 13.4 0.3 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Rnk_N PF14760.6 ORY00575.1 - 0.095 13.2 0.3 12 6.5 0.1 2.8 3 0 0 3 3 3 0 Rnk N-terminus DUF2688 PF10892.8 ORY00575.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Sec7 PF01369.20 ORY00576.1 - 7.5e-35 120.3 0.4 1.4e-34 119.4 0.4 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORY00576.1 - 1.6e-31 109.1 0.0 4e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY00576.1 - 7.3e-07 29.7 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 ORY00577.1 - 4.1e-60 203.4 0.0 4.8e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00577.1 - 2.2e-39 135.3 0.0 2.7e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00577.1 - 1.1e-06 28.2 0.0 2.7e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY00577.1 - 0.003 16.6 0.1 0.005 15.8 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Amidase_6 PF12671.7 ORY00577.1 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidase domain Pkinase_fungal PF17667.1 ORY00577.1 - 0.013 14.3 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY00577.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tom5 PF10642.9 ORY00578.1 - 8e-16 57.8 0.4 8.8e-16 57.7 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Ribosomal_L31e PF01198.19 ORY00579.1 - 3.3e-39 133.0 2.4 4.1e-39 132.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Phosducin PF02114.16 ORY00580.1 - 1.4e-14 53.7 0.2 1.6e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 ORY00580.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Glycogen_syn PF05693.13 ORY00582.1 - 0 1111.5 0.1 0 1111.3 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 ORY00582.1 - 1.1e-07 31.5 0.0 0.00035 20.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY00582.1 - 9.4e-07 28.8 0.1 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 ORY00582.1 - 4.3e-06 26.8 0.5 9.1e-06 25.8 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY00582.1 - 4.1e-05 24.1 0.1 7.2e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ORY00582.1 - 5.5e-05 23.6 0.0 0.073 13.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 ELFV_dehydrog PF00208.21 ORY00583.1 - 1e-09 38.5 0.0 3.4e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyoxalase PF00903.25 ORY00583.1 - 1.9e-08 34.6 5.4 6.1e-07 29.7 1.7 2.9 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY00583.1 - 8.4e-06 26.0 0.4 4e-05 23.8 0.3 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ELFV_dehydrog_N PF02812.18 ORY00583.1 - 2.8e-05 24.0 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ApbA PF02558.16 ORY00583.1 - 0.012 15.2 1.4 0.26 10.9 0.2 2.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PuR_N PF09182.10 ORY00583.1 - 0.061 13.3 0.0 0.26 11.3 0.0 2.1 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal MFS_1 PF07690.16 ORY00584.1 - 9.7e-25 87.2 61.8 1.7e-17 63.4 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Wzz PF02706.15 ORY00584.1 - 0.31 11.4 2.8 0.89 9.9 0.1 2.7 2 0 0 2 2 2 0 Chain length determinant protein DUF2374 PF09574.10 ORY00584.1 - 0.43 10.4 0.0 0.43 10.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) MFS_2 PF13347.6 ORY00584.1 - 0.46 9.0 26.2 0.24 9.9 20.2 2.3 1 1 1 2 2 2 0 MFS/sugar transport protein DUF443 PF04276.12 ORY00584.1 - 4.3 7.1 7.2 0.37 10.6 1.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF443) Glyco_hydro_61 PF03443.14 ORY00585.1 - 0.0016 18.4 0.0 0.2 11.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORY00585.1 - 0.0035 18.0 0.9 0.017 15.8 0.9 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_16 PF00722.21 ORY00586.1 - 3.5e-18 65.7 0.2 5e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 ORY00587.1 - 6e-17 61.7 0.2 9.1e-17 61.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Calreticulin PF00262.18 ORY00588.1 - 9.8e-05 21.4 9.1 0.087 11.7 0.6 2.8 1 1 2 3 3 3 3 Calreticulin family Colipase-like PF15083.6 ORY00588.1 - 0.97 9.6 12.5 3 8.0 2.0 3.3 1 1 2 3 3 3 0 Colipase-like zf-C2H2 PF00096.26 ORY00617.1 - 3.5e-10 39.8 9.3 3.6e-05 24.0 2.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY00617.1 - 3.1e-05 24.5 7.1 0.043 14.7 1.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY00617.1 - 0.00013 22.2 0.5 0.00013 22.2 0.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 ORY00617.1 - 0.0049 17.5 0.6 0.088 13.4 0.1 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY00617.1 - 0.013 15.8 0.8 0.056 13.7 0.8 1.7 1 1 0 1 1 1 0 C2H2-type zinc ribbon NIF PF03031.18 ORY00618.1 - 5.5e-27 94.5 1.7 7.3e-27 94.1 1.7 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_SAK_2 PF18143.1 ORY00618.1 - 0.0003 21.1 0.8 0.00072 19.9 0.8 1.6 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Peptidase_S49_N PF08496.10 ORY00618.1 - 0.23 11.5 3.6 0.4 10.7 3.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PolyA_pol PF01743.20 ORY00619.1 - 1.4e-14 54.6 0.0 5.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ORY00619.1 - 6.7e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Hexokinase_2 PF03727.16 ORY00623.1 - 4e-82 275.3 0.0 5.4e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY00623.1 - 3.1e-74 249.2 0.0 4.2e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase TPP_enzyme_N PF02776.18 ORY00623.1 - 0.18 11.4 0.5 0.78 9.3 0.1 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Hexokinase_2 PF03727.16 ORY00624.1 - 3e-81 272.4 0.0 4.1e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY00624.1 - 1.7e-74 250.1 0.1 2.5e-74 249.5 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Sugar_tr PF00083.24 ORY00625.1 - 4.4e-109 365.3 20.4 5e-109 365.1 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY00625.1 - 2.3e-25 89.3 30.6 2.3e-25 89.3 30.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Exo_endo_phos PF03372.23 ORY00626.1 - 2.5e-06 27.2 0.0 8.9e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cellulase PF00150.18 ORY00628.1 - 1.4e-09 37.8 0.7 2.6e-09 36.9 0.7 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 ORY00628.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily DUF3976 PF13121.6 ORY00628.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) COX6C PF02937.15 ORY00628.1 - 0.32 11.1 2.1 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc CsbD PF05532.12 ORY00629.1 - 3.2e-06 26.9 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CsbD-like CsbD PF05532.12 ORY00630.1 - 2.6e-17 62.4 21.6 1.1e-09 38.1 5.9 2.1 1 1 1 2 2 2 2 CsbD-like WD40 PF00400.32 ORY00631.1 - 2.2e-38 129.6 16.9 6.7e-07 29.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY00631.1 - 5.1e-19 68.4 0.0 0.021 15.1 0.1 5.9 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 ORY00631.1 - 7.1e-08 32.1 0.0 1.5e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 ORY00631.1 - 5.5e-07 28.9 0.6 0.19 10.7 0.1 3.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY00631.1 - 1.7e-05 23.5 0.6 0.0085 14.7 0.1 3.4 2 1 2 4 4 4 2 Cytochrome D1 heme domain eIF2A PF08662.11 ORY00631.1 - 4.7e-05 23.3 0.1 0.014 15.3 0.0 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY00631.1 - 0.0025 16.6 0.0 0.016 13.9 0.0 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORY00631.1 - 0.0025 16.8 0.9 0.33 9.8 0.2 2.2 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 ORY00631.1 - 0.0033 16.8 0.0 3.7 6.8 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain BCDHK_Adom3 PF10436.9 ORY00632.1 - 6e-19 68.5 1.4 9.3e-19 67.8 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY00632.1 - 1.5e-10 41.5 0.0 2.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY00632.1 - 0.0016 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M24 PF00557.24 ORY00633.1 - 7e-42 143.5 0.2 9.1e-42 143.1 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DDHD PF02862.17 ORY00633.1 - 0.28 11.3 2.8 0.41 10.8 2.8 1.3 1 0 0 1 1 1 0 DDHD domain PRTP PF01366.18 ORY00633.1 - 0.88 7.5 3.6 1.7 6.6 3.6 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RPN2_C PF18004.1 ORY00633.1 - 1.4 8.8 26.5 0.41 10.5 23.0 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TCP PF03634.13 ORY00633.1 - 2.3 8.8 12.9 4.6 7.8 12.9 1.4 1 0 0 1 1 1 0 TCP family transcription factor LYRIC PF15686.5 ORY00633.1 - 4.4 6.8 23.9 6.8 6.1 23.9 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family CDC45 PF02724.14 ORY00633.1 - 5.9 5.1 14.2 8.8 4.5 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Med8 PF10232.9 ORY00633.1 - 6 6.4 11.3 9.4 5.8 11.3 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Vfa1 PF08432.10 ORY00633.1 - 6.4 7.1 16.5 11 6.3 16.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3381 PF11861.8 ORY00633.1 - 7.2 6.4 19.5 17 5.2 19.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Zip PF02535.22 ORY00633.1 - 7.5 5.7 7.6 9.5 5.3 7.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ORY00633.1 - 8.1 5.1 10.7 9.8 4.8 10.7 1.1 1 0 0 1 1 1 0 Presenilin DinB_2 PF12867.7 ORY00634.1 - 0.00081 19.9 0.8 0.0015 19.1 0.8 1.5 1 1 0 1 1 1 1 DinB superfamily TAL_FSA PF00923.19 ORY00635.1 - 7.2e-104 347.2 0.8 8.1e-104 347.0 0.8 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Ras PF00071.22 ORY00636.1 - 1.1e-54 184.4 0.1 1.3e-54 184.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY00636.1 - 2.2e-20 73.1 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY00636.1 - 2.8e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY00636.1 - 0.00045 20.3 0.0 0.00065 19.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY00636.1 - 0.00066 19.3 0.2 0.0016 18.0 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 ORY00636.1 - 0.0099 15.1 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 ORY00636.1 - 0.016 15.1 0.7 1.9 8.4 0.5 2.3 1 1 0 2 2 2 0 RsgA GTPase GATA PF00320.27 ORY00637.1 - 4.2e-15 55.0 5.3 7.5e-15 54.3 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORY00637.1 - 9.5e-14 51.5 0.0 3.6e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 ORY00637.1 - 1.9e-12 47.2 0.0 3.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORY00637.1 - 4.3e-09 36.6 0.0 1.1e-08 35.3 0.0 1.6 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 ORY00637.1 - 2.2e-05 24.5 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORY00637.1 - 3.8e-05 23.9 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold TF_Zn_Ribbon PF08271.12 ORY00637.1 - 0.068 12.7 0.3 1 8.9 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY00637.1 - 0.085 13.0 0.7 0.19 11.9 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF241 PF03087.14 ORY00637.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF4448 PF14610.6 ORY00638.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rax2 PF12768.7 ORY00638.1 - 0.051 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity MapZ_C2 PF18708.1 ORY00638.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 DUF4451 PF14616.6 ORY00639.1 - 1.8e-19 70.1 10.2 2.9e-19 69.5 10.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) Cyclin_N PF00134.23 ORY00640.1 - 1.9e-42 144.0 0.3 1.9e-42 144.0 0.3 2.3 3 1 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY00640.1 - 1.8e-31 108.7 0.6 4.5e-31 107.4 0.6 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Hist_deacetyl PF00850.19 ORY00641.1 - 5.5e-83 279.0 0.5 7.2e-83 278.6 0.2 1.3 2 0 0 2 2 2 1 Histone deacetylase domain EccE PF11203.8 ORY00643.1 - 0.063 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Brix PF04427.18 ORY00643.1 - 0.087 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Brix domain SH3_1 PF00018.28 ORY00644.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SKN1 PF03935.15 ORY00645.1 - 4.5e-185 615.8 2.7 5.1e-185 615.6 2.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DHHC PF01529.20 ORY00676.1 - 2.2e-31 108.7 14.3 2.2e-31 108.7 14.3 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 ORY00676.1 - 2.5e-31 108.1 0.0 2.1e-16 60.3 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY00676.1 - 8e-28 93.4 0.8 7.6e-06 25.9 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 ORY00676.1 - 1.6e-25 88.8 0.3 2.4e-06 27.7 0.1 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY00676.1 - 3.7e-24 84.8 0.4 4.9e-06 27.0 0.0 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY00676.1 - 3.4e-18 65.2 2.4 0.0001 22.5 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Chitin_synth_2 PF03142.15 ORY00677.1 - 2.2e-254 845.0 0.2 3.4e-254 844.3 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY00677.1 - 2.9e-13 50.2 0.0 1.6e-12 47.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY00677.1 - 4.6e-13 49.5 6.3 2.4e-12 47.2 6.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY00677.1 - 0.036 13.5 0.0 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY00677.1 - 0.063 13.1 0.0 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 NIF PF03031.18 ORY00678.1 - 2.2e-55 186.7 0.1 2.9e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Arm-DNA-bind_5 PF17293.2 ORY00679.1 - 0.29 11.6 3.4 0.23 11.9 1.0 2.0 2 0 0 2 2 2 0 Arm DNA-binding domain Thioredoxin_8 PF13905.6 ORY00680.1 - 5.9e-25 87.4 0.1 8.6e-25 86.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 ORY00680.1 - 2.6e-11 43.4 0.1 8.9e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 ORY00680.1 - 3e-08 33.6 0.1 4.7e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY00680.1 - 2.1e-07 30.7 0.0 2.9e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 ORY00680.1 - 1.1e-06 28.7 0.1 2.3e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 ORY00680.1 - 2.4e-06 27.9 0.1 3.5e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ORY00680.1 - 1.2e-05 25.1 0.1 0.00023 20.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 ORY00680.1 - 0.0016 18.6 0.1 0.011 16.0 0.0 2.1 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin_7 PF13899.6 ORY00680.1 - 0.0021 18.2 0.1 0.0037 17.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 ORY00680.1 - 0.011 15.4 1.3 0.067 12.8 1.3 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.20 ORY00680.1 - 0.051 13.4 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Staygreen PF12638.7 ORY00680.1 - 0.087 12.6 0.3 0.72 9.6 0.0 2.0 1 1 1 2 2 2 0 Staygreen protein DUF1390 PF07150.11 ORY00680.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Peptidase_M16 PF00675.20 ORY00681.1 - 3e-42 144.1 1.7 4.8e-42 143.5 0.4 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY00681.1 - 1.3e-37 129.6 0.2 8.9e-36 123.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain PMT_4TMC PF16192.5 ORY00682.1 - 0.17 11.5 2.5 0.25 10.9 2.1 1.6 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase EF-hand_4 PF12763.7 ORY00683.1 - 7.2e-33 112.7 0.0 1.5e-18 66.6 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ORY00683.1 - 7.6e-09 35.9 0.0 5.3e-05 23.6 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY00683.1 - 4.8e-08 32.0 0.0 0.0097 15.4 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 ORY00683.1 - 0.00012 21.7 0.1 1 9.4 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain DUF4407 PF14362.6 ORY00683.1 - 0.0032 16.9 2.4 0.0032 16.9 2.4 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4407) Tup_N PF08581.10 ORY00683.1 - 0.31 11.4 6.9 2.6 8.4 0.1 3.6 3 0 0 3 3 3 0 Tup N-terminal zf-C2H2 PF00096.26 ORY00685.1 - 8.1e-15 54.4 10.8 3.5e-07 30.3 3.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY00685.1 - 3.7e-11 42.9 11.7 1.3e-08 34.9 1.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY00685.1 - 3.3e-09 36.8 8.3 0.00051 20.7 2.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY00685.1 - 1.6e-05 24.8 3.5 0.0066 16.4 1.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY00685.1 - 0.0034 17.6 0.5 0.073 13.4 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding OSTMP1 PF09777.9 ORY00685.1 - 0.016 14.6 0.1 0.017 14.5 0.1 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-TRAF PF02176.18 ORY00685.1 - 0.026 15.2 2.2 0.033 14.9 2.2 1.2 1 0 0 1 1 1 0 TRAF-type zinc finger GAGA PF09237.11 ORY00685.1 - 0.029 14.2 1.5 0.029 14.2 1.5 1.7 1 1 1 2 2 2 0 GAGA factor zf-C2H2_8 PF15909.5 ORY00685.1 - 0.03 14.6 0.5 0.048 13.9 0.5 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 ORY00685.1 - 0.058 14.1 1.4 3.1 8.5 0.2 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 ORY00685.1 - 0.074 13.4 2.3 0.28 11.5 1.3 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 ORY00685.1 - 0.083 13.4 0.5 0.083 13.4 0.5 1.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CCAP PF11105.8 ORY00685.1 - 0.16 11.9 0.4 0.17 11.9 0.4 1.1 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-BED PF02892.15 ORY00685.1 - 0.18 11.9 6.2 0.39 10.8 1.6 2.2 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 ORY00685.1 - 1.9 8.3 16.1 0.44 10.3 1.9 2.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Sel1 PF08238.12 ORY00686.1 - 8.9e-46 153.3 17.0 3.4e-08 33.9 0.0 8.2 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 ORY00686.1 - 0.0095 16.5 2.1 37 5.3 0.0 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY00686.1 - 0.057 13.1 9.5 0.42 10.3 0.0 4.7 4 0 0 4 4 4 0 TPR repeat ANAPC3 PF12895.7 ORY00686.1 - 0.1 12.9 4.2 4 7.7 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.22 ORY00687.1 - 4.8e-50 169.3 0.1 5.9e-50 169.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY00687.1 - 2.2e-35 121.4 0.0 4.2e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY00687.1 - 3.8e-17 62.3 0.0 5.2e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY00687.1 - 7.8e-09 35.2 0.2 9.9e-09 34.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY00687.1 - 8.9e-07 29.0 0.7 0.012 15.5 0.0 2.6 1 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 ORY00687.1 - 0.00022 20.7 0.0 0.00039 19.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY00687.1 - 0.00033 20.7 0.0 0.00047 20.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY00687.1 - 0.00033 21.1 0.0 0.00055 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 ORY00687.1 - 0.0068 16.2 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORY00687.1 - 0.026 14.8 0.5 0.67 10.2 0.5 2.7 1 1 0 1 1 1 0 AAA domain YwhD PF08741.10 ORY00687.1 - 0.039 13.6 0.5 0.069 12.8 0.0 1.6 2 0 0 2 2 2 0 YwhD family AAA_5 PF07728.14 ORY00687.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORY00687.1 - 0.058 13.1 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY00687.1 - 0.26 10.2 2.8 0.21 10.5 0.8 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 ORY00687.1 - 0.32 11.2 1.4 1 9.6 0.1 2.3 2 1 1 3 3 3 0 AAA domain Zip PF02535.22 ORY00688.1 - 1.6e-22 80.2 12.4 1.3e-21 77.2 12.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Trp_oprn_chp PF09534.10 ORY00688.1 - 0.4 10.5 3.9 14 5.4 0.3 3.0 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NUDE_C PF04880.13 ORY00689.1 - 7.2e-08 33.1 16.0 7.2e-08 33.1 16.0 3.2 2 2 0 2 2 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.8 ORY00689.1 - 7.3e-05 20.5 19.0 9.6e-05 20.1 19.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 ORY00689.1 - 0.00058 19.9 32.3 0.031 14.3 11.4 3.2 1 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein AIP3 PF03915.13 ORY00689.1 - 0.00063 18.9 17.7 0.0028 16.8 18.6 1.5 1 1 1 2 2 2 1 Actin interacting protein 3 E2R135 PF11570.8 ORY00689.1 - 0.0031 17.8 5.4 0.53 10.6 1.6 2.6 1 1 1 2 2 2 2 Coiled-coil receptor-binding R-domain of colicin E2 Spc7 PF08317.11 ORY00689.1 - 0.0071 15.3 28.8 0.022 13.6 28.4 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 ORY00689.1 - 0.014 14.8 33.0 0.077 12.3 14.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 ORY00689.1 - 0.031 14.3 19.5 0.11 12.5 4.6 2.5 2 1 1 3 3 2 0 Laminin Domain II DUF4686 PF15742.5 ORY00689.1 - 0.038 13.1 31.5 0.036 13.2 23.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) ADIP PF11559.8 ORY00689.1 - 0.053 13.6 28.3 0.42 10.7 6.3 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ApoO PF09769.9 ORY00689.1 - 0.06 13.3 7.9 3 7.8 0.3 3.3 2 1 1 3 3 3 0 Apolipoprotein O Filament PF00038.21 ORY00689.1 - 0.062 12.9 27.8 0.032 13.8 8.8 2.7 1 1 2 3 3 3 0 Intermediate filament protein DUF2353 PF09789.9 ORY00689.1 - 0.071 12.5 26.6 0.13 11.6 11.4 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) CALCOCO1 PF07888.11 ORY00689.1 - 0.085 11.7 26.2 0.55 9.0 26.5 1.9 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like IFT57 PF10498.9 ORY00689.1 - 0.086 11.8 24.7 2.6 6.9 15.1 3.0 2 1 0 3 3 3 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 ORY00689.1 - 0.086 13.3 24.5 1.5 9.2 10.9 2.2 1 1 1 2 2 2 0 Fez1 DUF948 PF06103.11 ORY00689.1 - 0.092 13.0 12.9 1.3 9.3 1.4 3.4 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 ORY00689.1 - 0.094 12.8 16.8 1 9.4 3.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 ORY00689.1 - 0.13 12.5 21.7 0.71 10.2 11.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Pox_A_type_inc PF04508.12 ORY00689.1 - 0.15 12.0 20.8 0.4 10.6 0.1 5.1 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.12 ORY00689.1 - 0.2 12.2 12.3 7.4 7.1 0.5 3.9 2 1 3 5 5 4 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 ORY00689.1 - 0.27 11.6 26.9 90 3.4 22.1 3.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 ORY00689.1 - 0.35 9.4 22.3 0.88 8.1 22.4 1.5 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 ORY00689.1 - 0.36 10.8 35.8 2.6 8.1 23.1 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 ORY00689.1 - 0.42 10.3 26.3 1 9.1 1.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 ORY00689.1 - 0.47 11.0 21.8 0.18 12.3 2.4 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 ORY00689.1 - 0.63 10.4 18.6 3.1 8.2 5.7 2.4 1 1 1 2 2 2 0 Syntaxin-like protein TACC_C PF05010.14 ORY00689.1 - 0.72 9.6 26.4 48 3.7 26.5 2.8 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FUSC PF04632.12 ORY00689.1 - 0.78 8.2 10.6 1.2 7.6 5.2 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family SlyX PF04102.12 ORY00689.1 - 1.1 9.9 24.2 1.1 9.9 1.9 4.9 2 1 4 6 6 6 0 SlyX DUF4407 PF14362.6 ORY00689.1 - 1.2 8.5 17.6 6 6.1 17.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 ORY00689.1 - 1.2 9.4 25.0 2.1 8.6 8.7 3.5 2 1 2 4 4 3 0 Seryl-tRNA synthetase N-terminal domain DUF4763 PF15960.5 ORY00689.1 - 1.5 8.1 22.1 5.8 6.1 20.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) PSII_Pbs27 PF13326.6 ORY00689.1 - 1.5 9.1 7.9 1.9 8.8 3.1 2.3 1 1 1 2 2 2 0 Photosystem II Pbs27 Golgin_A5 PF09787.9 ORY00689.1 - 1.6 8.2 30.0 2.6 7.4 18.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 PspA_IM30 PF04012.12 ORY00689.1 - 1.6 8.2 25.0 0.53 9.8 11.3 2.4 2 1 1 3 3 2 0 PspA/IM30 family UPF0242 PF06785.11 ORY00689.1 - 1.7 8.7 34.4 0.17 12.0 21.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 ORY00689.1 - 1.9 7.9 33.4 30 3.9 33.4 2.2 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 ORY00689.1 - 1.9 7.7 25.3 0.059 12.7 7.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 ORY00689.1 - 2.1 7.1 24.2 0.56 9.0 14.0 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain COG5 PF10392.9 ORY00689.1 - 2.2 8.5 13.8 0.72 10.0 1.3 3.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Cytochrom_B562 PF07361.11 ORY00689.1 - 2.4 8.8 13.6 9.4 7.0 6.3 2.7 1 1 0 2 2 2 0 Cytochrome b562 Rab5-bind PF09311.11 ORY00689.1 - 2.4 7.4 26.2 0.37 10.1 8.0 2.2 1 1 1 2 2 2 0 Rabaptin-like protein BLOC1_2 PF10046.9 ORY00689.1 - 2.8 8.3 23.0 2.4 8.5 2.4 4.4 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA2 PF16740.5 ORY00689.1 - 3 7.6 21.6 8.1 6.3 9.7 3.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 ERM PF00769.19 ORY00689.1 - 3.2 7.5 35.9 2.5 7.9 16.9 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family EzrA PF06160.12 ORY00689.1 - 3.3 5.8 28.1 66 1.5 28.0 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Prominin PF05478.11 ORY00689.1 - 4.8 5.0 14.8 25 2.6 14.8 2.0 1 1 0 1 1 1 0 Prominin CENP-H PF05837.12 ORY00689.1 - 4.9 7.6 26.4 4.4 7.7 10.2 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HIP1_clath_bdg PF16515.5 ORY00689.1 - 6.7 7.4 29.0 0.99 10.1 4.5 3.3 2 1 2 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4472 PF14739.6 ORY00689.1 - 6.7 7.5 25.5 11 6.8 9.8 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF4200 PF13863.6 ORY00689.1 - 7.3 7.0 32.1 0.55 10.6 13.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ZapB PF06005.12 ORY00689.1 - 8.3 6.9 38.1 0.13 12.7 7.9 4.2 1 1 2 3 3 2 0 Cell division protein ZapB DUF148 PF02520.17 ORY00689.1 - 8.4 6.5 16.5 0.55 10.4 9.2 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF2203 PF09969.9 ORY00689.1 - 8.5 7.1 18.5 7.3 7.3 5.9 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) T3SSipB PF16535.5 ORY00689.1 - 8.6 6.8 11.4 70 3.9 11.2 2.2 1 1 0 1 1 1 0 Type III cell invasion protein SipB Rootletin PF15035.6 ORY00689.1 - 9.1 6.3 32.8 5.3 7.0 1.7 3.2 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Med9 PF07544.13 ORY00689.1 - 9.9 6.3 19.4 1.4 9.0 6.3 4.1 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 ATP-grasp_2 PF08442.10 ORY00690.1 - 1e-75 253.8 1.0 1.7e-75 253.0 1.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ORY00690.1 - 4.3e-25 88.3 1.2 1.1e-24 87.0 0.8 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 ORY00690.1 - 4.6e-08 32.8 0.3 8.9e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ORY00690.1 - 0.0024 17.7 0.2 0.0061 16.4 0.2 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 ORY00690.1 - 0.022 14.6 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain EFhand_Ca_insen PF08726.10 ORY00690.1 - 0.18 11.9 0.3 5.6 7.1 0.1 2.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Catalase PF00199.19 ORY00691.1 - 2.7e-181 602.8 0.3 3.7e-181 602.4 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY00691.1 - 9.5e-20 70.6 0.0 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 ORY00691.1 - 2e-16 60.0 0.0 4.7e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 ORY00691.1 - 3.2e-10 40.1 0.0 7.5e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Opacity PF02462.15 ORY00691.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Opacity family porin protein Ribosomal_L33 PF00471.20 ORY00694.1 - 1.6e-10 41.2 0.0 2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 UQ_con PF00179.26 ORY00695.1 - 4e-48 162.6 0.0 4.5e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY00695.1 - 6.7e-05 22.6 0.0 8.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY00695.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 ORY00695.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.4 1 1 0 1 1 1 0 RWD domain Yippee-Mis18 PF03226.14 ORY00696.1 - 1.3e-23 83.2 1.9 3.5e-23 81.8 1.9 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RNase_PH PF01138.21 ORY00697.1 - 3.9e-22 79.2 0.0 7.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY00697.1 - 0.00017 21.6 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PetG PF02529.15 ORY00698.1 - 0.014 15.3 1.7 0.026 14.3 0.4 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF2157 PF09925.9 ORY00698.1 - 0.014 15.2 3.0 0.014 15.2 3.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) TssN PF17555.2 ORY00698.1 - 0.087 12.2 4.5 0.095 12.1 4.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2427 PF10348.9 ORY00698.1 - 0.13 12.0 2.7 0.24 11.2 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) PsbL PF02419.17 ORY00698.1 - 0.14 12.2 2.4 0.35 10.9 2.4 1.7 1 0 0 1 1 1 0 PsbL protein VirB8 PF04335.13 ORY00698.1 - 0.2 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 VirB8 protein Ran_BP1 PF00638.18 ORY00699.1 - 8e-27 93.9 1.0 1.5e-26 93.0 1.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Macoilin PF09726.9 ORY00699.1 - 0.1 11.1 13.1 0.12 10.9 13.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF4337 PF14235.6 ORY00699.1 - 4.8 7.3 5.3 8.7 6.4 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Barttin PF15462.6 ORY00699.1 - 6.6 6.4 13.7 12 5.6 13.7 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Lin-8 PF03353.15 ORY00699.1 - 7.4 6.0 16.7 9.7 5.6 16.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ribosomal_L19e PF01280.20 ORY00700.1 - 3.2e-65 218.6 10.6 3.2e-65 218.6 10.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Ribosomal_S13 PF00416.22 ORY00701.1 - 1.2e-55 187.3 2.5 2e-55 186.6 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 GEMIN8 PF15348.6 ORY00701.1 - 6.1e-11 43.1 0.0 9.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 DUF3807 PF12720.7 ORY00701.1 - 0.0035 17.6 1.2 0.0079 16.5 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) FbpA PF05833.11 ORY00701.1 - 0.019 13.7 0.0 0.033 12.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1631 PF07793.11 ORY00701.1 - 0.072 11.5 1.3 0.096 11.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) TFIID_NTD2 PF04494.15 ORY00702.1 - 2.5e-44 150.6 3.8 2.8e-44 150.5 2.6 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 ORY00702.1 - 5.9e-42 140.8 20.7 2.7e-09 37.5 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY00702.1 - 4.7e-13 49.2 0.4 0.071 13.4 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY00702.1 - 0.0015 17.3 0.7 1.3 7.6 0.0 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY00702.1 - 0.028 13.4 0.1 5 6.0 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 ORY00702.1 - 0.11 12.5 0.3 0.63 10.1 0.0 2.4 2 0 0 2 2 2 0 LisH vATP-synt_E PF01991.18 ORY00703.1 - 7.7e-64 214.8 13.5 8.9e-64 214.6 13.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Par3_HAL_N_term PF12053.8 ORY00703.1 - 0.0014 18.8 0.8 0.83 9.9 0.1 2.6 1 1 1 2 2 2 2 N-terminal of Par3 and HAL proteins DUF883 PF05957.13 ORY00703.1 - 1.5 9.5 6.0 0.98 10.1 1.2 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) EamA PF00892.20 ORY00705.1 - 1.1e-05 25.6 9.0 3.5e-05 24.0 9.0 1.8 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 ORY00705.1 - 0.00079 19.5 2.2 0.0012 18.9 2.2 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 ORY00705.1 - 0.037 14.7 0.2 0.037 14.7 0.2 1.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein Pkinase PF00069.25 ORY00706.1 - 1.1e-26 93.9 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00706.1 - 2.5e-15 56.4 0.0 3.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY00706.1 - 3.1e-08 32.8 0.1 5.5e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORY00706.1 - 0.016 14.2 0.2 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY00706.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Shadoo PF14999.6 ORY00706.1 - 0.13 12.3 6.2 0.19 11.8 6.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective EF-hand_6 PF13405.6 ORY00707.1 - 1.8e-13 49.2 10.1 2.1e-07 30.3 1.6 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 ORY00707.1 - 7e-13 47.1 14.2 2.2e-06 26.8 3.1 4.6 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 ORY00707.1 - 2.2e-11 44.0 5.9 1.7e-05 25.2 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY00707.1 - 3.9e-08 32.4 4.7 0.00013 21.3 2.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORY00707.1 - 2e-07 30.7 7.3 0.0025 17.6 1.0 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_11 PF08976.11 ORY00707.1 - 0.0021 18.9 0.1 0.0057 17.5 0.1 1.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 ORY00707.1 - 0.0027 18.0 0.5 0.92 9.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain UPF0154 PF03672.13 ORY00707.1 - 0.099 12.7 0.0 1.7 8.7 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) RNA_pol_N PF01194.17 ORY00709.1 - 4e-33 113.5 0.5 4.6e-33 113.3 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 ORY00710.1 - 1.3e-23 82.8 11.2 9.3e-06 26.3 0.0 10.1 9 1 1 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY00710.1 - 2.2e-08 34.3 0.0 0.37 11.1 0.0 6.7 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY00710.1 - 0.039 13.8 0.2 40 4.0 0.0 4.0 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A ubiquitin PF00240.23 ORY00711.1 - 9.4e-08 31.7 0.2 2.7e-07 30.3 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY00711.1 - 8.8e-06 26.1 0.1 5.3e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 ORY00711.1 - 0.0061 16.4 0.4 0.028 14.2 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.18 ORY00711.1 - 0.07 13.3 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain UQ_con PF00179.26 ORY00712.1 - 3.5e-33 114.2 0.0 4.2e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S19e PF01090.19 ORY00713.1 - 9e-58 193.8 0.2 1e-57 193.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e PP-binding PF00550.25 ORY00714.1 - 1.7e-13 50.7 0.1 2.1e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORY00714.1 - 1.6e-05 25.1 0.3 1.9e-05 24.8 0.3 1.1 1 0 0 1 1 1 1 Acyl-carrier HAMP PF00672.25 ORY00714.1 - 0.028 14.8 0.1 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 HAMP domain ADH_N PF08240.12 ORY00717.1 - 1.1e-33 115.4 1.4 2.1e-33 114.5 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY00717.1 - 4.8e-28 97.7 0.1 7.4e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY00717.1 - 3.1e-07 31.5 0.1 5.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY00717.1 - 0.0013 18.2 0.3 0.0026 17.2 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 ORY00717.1 - 0.0063 15.8 0.2 0.0099 15.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY00717.1 - 0.021 14.2 0.2 0.038 13.3 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SCPU PF05229.15 ORY00722.1 - 0.031 14.7 0.4 0.045 14.1 0.4 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain Defb50 PF17546.2 ORY00722.1 - 0.046 13.6 0.8 0.096 12.6 0.3 1.8 2 0 0 2 2 2 0 Beta defensin 50 LRR_4 PF12799.7 ORY00755.1 - 0.046 14.2 35.7 1.1 9.7 0.1 10.0 6 5 5 11 11 11 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY00755.1 - 0.27 11.0 21.5 0.28 11.0 0.2 6.4 5 3 1 7 7 7 0 Leucine rich repeat LRR_6 PF13516.6 ORY00755.1 - 0.87 9.8 11.7 4.7 7.5 0.1 7.2 11 0 0 11 11 11 0 Leucine Rich repeat PLDc_2 PF13091.6 ORY00757.1 - 1.9e-18 66.7 1.0 4e-09 36.5 0.1 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 ORY00757.1 - 3.7e-15 55.4 1.8 8e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PP2C PF00481.21 ORY00758.1 - 2.7e-43 148.4 0.0 4e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY00758.1 - 2.6e-05 24.0 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORY00758.1 - 0.099 12.6 0.0 22 4.9 0.0 3.2 2 2 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PRELI PF04707.14 ORY00759.1 - 1.4e-45 154.9 0.0 1.7e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Ras PF00071.22 ORY00760.1 - 1.2e-54 184.3 0.0 1.4e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY00760.1 - 9.5e-22 77.5 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY00760.1 - 5.6e-06 25.9 0.0 7.4e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY00760.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY00760.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Myb_DNA-bind_4 PF13837.6 ORY00762.1 - 4e-13 49.5 0.3 6.3e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY00762.1 - 1.3e-06 28.5 0.6 2.8e-06 27.4 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY00762.1 - 1.3e-05 25.4 0.3 2.3e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY00762.1 - 0.00042 20.6 0.1 0.00079 19.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORY00762.1 - 0.018 16.0 0.1 0.026 15.5 0.1 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORY00762.1 - 0.033 14.3 2.2 0.06 13.4 1.8 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Gln-synt_C PF00120.24 ORY00763.1 - 1e-72 245.1 0.0 1.3e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain PseudoU_synth_2 PF00849.22 ORY00764.1 - 6.7e-25 88.0 0.0 9.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_S24 PF00717.23 ORY00765.1 - 3.3e-07 30.2 0.1 6.4e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ORY00765.1 - 0.018 14.8 0.0 2 8.2 0.0 2.6 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Pectate_lyase_3 PF12708.7 ORY00766.1 - 1.6e-06 28.1 1.0 6.1e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Pectate lyase superfamily protein SPRY PF00622.28 ORY00767.1 - 1.7e-16 60.4 0.2 3.4e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 ORY00767.1 - 1.8e-09 37.3 5.4 3e-09 36.6 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY00767.1 - 0.00025 20.8 7.8 0.00053 19.8 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY00767.1 - 0.0011 19.3 7.3 0.0023 18.2 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORY00767.1 - 0.0047 16.8 7.8 0.0091 15.8 7.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PAS_3 PF08447.12 ORY00768.1 - 3.1e-13 49.8 0.1 3.9e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORY00768.1 - 3.6e-10 39.8 0.0 4.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY00768.1 - 2e-05 24.8 0.0 0.029 14.6 0.0 2.5 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.6 ORY00768.1 - 0.0016 18.5 0.2 1.3 9.2 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_12 PF18095.1 ORY00768.1 - 0.013 15.2 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain PAS_4 PF08448.10 ORY00768.1 - 0.034 14.4 0.0 0.87 9.9 0.0 2.2 2 0 0 2 2 2 0 PAS fold DNA_pol_A_exo1 PF01612.20 ORY00769.1 - 2.9e-19 69.4 0.4 3.7e-19 69.1 0.4 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DUF5128 PF17170.4 ORY00769.1 - 0.016 14.4 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 6-bladed beta-propeller Bac_globin PF01152.21 ORY00770.1 - 1.6e-06 28.2 0.5 1.9e-06 28.0 0.5 1.1 1 0 0 1 1 1 1 Bacterial-like globin DUF2999 PF11212.8 ORY00770.1 - 0.038 14.3 0.1 5 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) FAD-SLDH PF12318.8 ORY00770.1 - 0.05 13.7 0.3 0.055 13.5 0.3 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Methyltransf_25 PF13649.6 ORY00770.1 - 0.057 14.1 0.6 0.16 12.7 0.3 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY00770.1 - 0.11 13.2 0.1 0.17 12.6 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.23 ORY00771.1 - 5.9e-59 199.5 0.0 9.1e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 ORY00771.1 - 2.4e-16 60.4 5.3 6.2e-16 59.1 5.3 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 ORY00771.1 - 8.7e-16 58.3 0.0 3.4e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY00771.1 - 2.5e-08 34.1 0.0 5.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY00771.1 - 5.6e-06 25.7 0.1 2.5e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 ORY00771.1 - 0.0013 19.1 0.3 1.6 9.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain ERCC3_RAD25_C PF16203.5 ORY00771.1 - 0.0037 16.5 0.1 0.0066 15.7 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase POP1 PF06978.11 ORY00772.1 - 5.2e-47 160.5 18.7 6e-25 88.5 9.7 2.7 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 ORY00772.1 - 1.5e-32 111.8 0.2 1.6e-31 108.5 0.2 2.7 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 ORY00772.1 - 1.2e-07 31.4 0.0 0.00053 19.4 0.0 3.1 2 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORY00772.1 - 0.035 14.0 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Telomere_reg-2 PF10193.9 ORY00773.1 - 7.6e-28 97.1 0.1 1.8e-27 96.0 0.1 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Syntaxin_2 PF14523.6 ORY00773.1 - 0.0088 16.4 0.3 0.035 14.5 0.0 2.1 2 0 0 2 2 2 1 Syntaxin-like protein DivIC PF04977.15 ORY00774.1 - 0.32 10.8 2.1 0.85 9.4 2.1 1.7 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 ORY00774.1 - 3.3 8.2 8.8 0.29 11.6 3.2 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Sulfotransfer_1 PF00685.27 ORY00775.1 - 6.1e-29 101.3 0.2 8.6e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY00775.1 - 6.7e-06 26.6 0.2 0.00063 20.2 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 ORY00775.1 - 0.09 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Aminotran_1_2 PF00155.21 ORY00776.1 - 1.2e-60 205.6 0.0 1.5e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY00776.1 - 1.3e-05 24.4 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 ORY00776.1 - 0.00094 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 ORY00776.1 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Acetyltransf_1 PF00583.25 ORY00777.1 - 2.6e-13 50.2 0.4 3.2e-13 49.9 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY00777.1 - 4.4e-06 27.0 0.2 6.5e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY00777.1 - 1.1e-05 25.3 0.1 1.5e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sec63 PF02889.16 ORY00777.1 - 0.03 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Sec63 Brl domain DUF2838 PF10998.8 ORY00778.1 - 3.3e-41 140.0 12.0 3.3e-41 140.0 12.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF454 PF04304.13 ORY00778.1 - 0.0028 17.7 0.6 0.0028 17.7 0.6 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF454) OSR1_C PF12202.8 ORY00779.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain GMC_oxred_N PF00732.19 ORY00781.1 - 1.5e-53 182.1 0.5 2.2e-53 181.6 0.5 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY00781.1 - 7.2e-24 84.9 0.0 1.9e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY00781.1 - 3.7e-11 42.7 3.9 0.00011 21.4 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY00781.1 - 2e-09 37.1 1.8 0.0028 16.9 0.2 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 ORY00781.1 - 9.5e-06 24.4 0.1 1.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.17 ORY00781.1 - 0.0032 16.8 0.4 0.02 14.1 1.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY00781.1 - 0.0044 15.8 2.7 0.037 12.7 0.7 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ORY00781.1 - 0.0048 16.5 9.6 0.31 10.6 10.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY00781.1 - 0.0056 16.9 5.5 0.0074 16.5 2.4 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY00781.1 - 0.017 14.4 1.2 0.027 13.7 1.2 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ORY00781.1 - 0.021 14.5 0.3 0.046 13.4 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ORY00781.1 - 0.039 13.2 1.8 0.33 10.1 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY00781.1 - 0.083 11.9 2.3 0.085 11.9 0.5 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ORY00781.1 - 0.49 9.7 3.9 3.2 7.0 3.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rhomboid PF01694.22 ORY00783.1 - 3.1e-36 124.7 11.1 5.6e-36 123.8 11.1 1.4 1 0 0 1 1 1 1 Rhomboid family PspC PF04024.12 ORY00783.1 - 0.2 11.5 5.8 19 5.2 2.2 3.7 3 1 0 3 3 3 0 PspC domain CNH PF00780.22 ORY00784.1 - 1.9e-49 168.7 0.1 3.3e-49 168.0 0.1 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY00784.1 - 1.8e-35 122.8 7.6 4.7e-35 121.5 7.6 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY00784.1 - 1.2e-16 61.1 0.0 4.9e-10 39.6 0.0 2.7 1 1 1 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 ORY00784.1 - 3.1e-05 23.8 0.0 9e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY00784.1 - 5.2e-05 23.7 0.1 0.00055 20.4 0.0 2.9 3 1 1 4 4 4 1 PH domain PH_16 PF17838.1 ORY00784.1 - 0.093 12.6 0.0 3.7 7.4 0.0 2.8 2 0 0 2 2 2 0 PH domain Cullin PF00888.22 ORY00785.1 - 4.3e-217 722.6 8.7 5.1e-217 722.3 8.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY00785.1 - 9.6e-29 99.2 4.2 1.8e-28 98.3 1.1 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain Yos9_DD PF17880.1 ORY00785.1 - 0.0052 16.9 0.8 0.029 14.5 0.1 2.7 3 0 0 3 3 3 1 Yos9 dimerzation domain Ribosomal_S6e PF01092.19 ORY00786.1 - 1.9e-60 202.3 0.0 3.6e-60 201.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e UCR_14kD PF02271.16 ORY00787.1 - 1.9e-42 143.3 0.4 2.2e-42 143.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.11 ORY00787.1 - 0.064 13.1 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family TolA_bind_tri PF16331.5 ORY00788.1 - 0.0025 17.9 1.1 0.0025 17.9 1.1 4.9 4 0 0 4 4 4 1 TolA binding protein trimerisation PRKG1_interact PF15898.5 ORY00788.1 - 0.0046 17.8 12.1 0.0046 17.8 12.1 5.4 4 2 1 5 5 5 1 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 ORY00788.1 - 0.039 14.0 0.7 0.039 14.0 0.7 5.0 5 1 0 5 5 4 0 bZIP transcription factor Fez1 PF06818.15 ORY00788.1 - 0.22 12.0 45.1 0.063 13.7 17.5 3.6 2 1 1 3 3 3 0 Fez1 HOOK PF05622.12 ORY00788.1 - 0.22 9.6 50.3 0.15 10.1 16.9 3.5 2 2 2 4 4 4 0 HOOK protein MtrB PF05440.12 ORY00788.1 - 0.34 11.3 2.0 1.3 9.5 0.1 2.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Baculo_PEP_C PF04513.12 ORY00788.1 - 0.93 9.5 17.0 2.6 8.1 0.5 4.0 4 0 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 ORY00788.1 - 1.7 8.0 29.7 1.2 8.4 6.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.18 ORY00788.1 - 1.8 8.7 17.7 1.9 8.6 2.1 3.7 2 1 1 3 3 3 0 Cobalamin adenosyltransferase NPV_P10 PF05531.12 ORY00788.1 - 3.4 8.2 11.6 4.6 7.8 0.4 4.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_M16 PF00675.20 ORY00788.1 - 3.4 7.6 12.3 0.026 14.5 2.5 2.5 2 1 0 2 2 2 0 Insulinase (Peptidase family M16) FlaC_arch PF05377.11 ORY00788.1 - 3.8 8.0 19.3 0.49 10.8 0.4 4.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 ORY00788.1 - 6 6.4 45.7 3.7 7.0 4.4 3.4 2 1 1 3 3 3 0 Intermediate filament protein LPP PF04728.13 ORY00788.1 - 7.6 7.0 10.3 57 4.2 0.2 4.5 3 1 1 4 4 4 0 Lipoprotein leucine-zipper RabGAP-TBC PF00566.18 ORY00789.1 - 2.8e-48 164.4 1.2 3.9e-48 163.9 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 ORY00789.1 - 6.4e-31 106.6 8.6 1.5e-24 86.1 0.4 3.3 3 0 0 3 3 3 2 GRAM domain EF-hand_7 PF13499.6 ORY00789.1 - 1.3e-06 28.8 1.6 0.0037 17.7 0.2 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY00789.1 - 2.7e-06 26.9 4.6 0.015 15.2 0.4 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ORY00789.1 - 0.038 13.6 1.8 1.9 8.2 0.2 3.1 2 0 0 2 2 2 0 EF hand DUF956 PF06115.11 ORY00789.1 - 0.21 11.3 0.8 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF956) Swi3 PF07962.12 ORY00790.1 - 2.7e-05 24.1 0.4 5.2e-05 23.2 0.3 1.7 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 RF-1 PF00472.20 ORY00790.1 - 0.57 10.1 6.9 0.072 13.0 2.8 1.5 2 0 0 2 2 2 0 RF-1 domain CCDC-167 PF15188.6 ORY00790.1 - 9.8 6.6 10.4 9 6.7 5.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4448 PF14610.6 ORY00791.1 - 0.00029 20.7 0.8 0.0026 17.6 0.5 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 ORY00791.1 - 0.057 13.2 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 ORY00791.1 - 0.15 12.9 0.0 0.26 12.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mito_carr PF00153.27 ORY00792.1 - 4.1e-69 228.6 4.1 1.9e-23 82.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORY00792.1 - 1.6e-10 41.3 3.8 6.1e-07 29.8 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY00792.1 - 6.5e-10 37.9 6.5 0.0075 15.7 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ORY00792.1 - 4e-08 32.5 6.3 0.021 14.7 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 ORY00792.1 - 8.1e-07 28.8 1.0 0.091 12.6 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY00792.1 - 0.0005 19.4 13.5 0.38 10.3 0.3 3.8 4 0 0 4 4 4 3 EF hand Cullin_binding PF03556.15 ORY00792.1 - 0.036 14.5 0.2 0.11 13.0 0.0 1.8 2 1 0 2 2 2 0 Cullin binding SPARC_Ca_bdg PF10591.9 ORY00792.1 - 0.16 12.3 0.1 23 5.4 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Mito_carr PF00153.27 ORY00793.1 - 5.2e-75 247.5 5.6 1.4e-26 92.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 ORY00793.1 - 0.0031 17.6 0.2 1.8 8.7 0.0 3.2 3 0 0 3 3 3 2 PrcB C-terminal Trypsin PF00089.26 ORY00794.1 - 3.3e-40 138.3 0.3 4.7e-40 137.7 0.3 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY00794.1 - 1.1e-07 32.9 0.0 1.6e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 ORY00794.1 - 0.093 13.1 0.1 0.3 11.5 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Peptidase_C3 PF00548.20 ORY00794.1 - 0.14 12.0 1.1 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) Heme_oxygenase PF01126.20 ORY00795.1 - 1.8e-29 103.0 0.9 2.7e-29 102.4 0.9 1.2 1 0 0 1 1 1 1 Heme oxygenase DUF1518 PF07469.12 ORY00795.1 - 0.47 10.9 0.9 38 4.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) DUF3421 PF11901.8 ORY00796.1 - 5.2e-32 110.2 4.4 4e-18 65.5 0.4 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3421 PF11901.8 ORY00798.1 - 3.8e-32 110.7 4.3 2.9e-18 65.9 0.4 2.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) ProRS-C_1 PF09180.11 ORY00800.1 - 4.8e-25 87.6 1.0 9.8e-25 86.6 1.0 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 ORY00800.1 - 8.3e-17 61.7 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 ORY00800.1 - 7.5e-13 48.6 0.1 1.3e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 ORY00800.1 - 8.7e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.19 ORY00800.1 - 0.0041 17.7 1.7 0.0041 17.7 1.7 3.1 4 0 0 4 4 4 1 60s Acidic ribosomal protein AIM3 PF17096.5 ORY00801.1 - 0.014 16.3 0.5 0.036 15.0 0.5 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 TMA7 PF09072.10 ORY00802.1 - 2.4e-29 102.0 23.2 2.6e-29 101.8 23.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 ORY00803.1 - 1.8e-70 237.3 0.0 2.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00803.1 - 1.8e-35 122.5 0.0 2.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00803.1 - 0.00016 21.1 0.0 0.00058 19.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY00803.1 - 0.006 15.6 0.1 0.018 14.0 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY00803.1 - 0.083 11.6 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF1518 PF07469.12 ORY00803.1 - 1.5 9.2 7.7 3 8.3 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) Mito_carr PF00153.27 ORY00804.1 - 5.3e-52 173.7 0.8 8.7e-20 70.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_5 PF05631.14 ORY00805.1 - 8.7e-89 297.9 7.9 1.2e-88 297.4 7.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ORY00805.1 - 1.9e-20 73.1 29.2 1.9e-20 73.1 29.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 ORY00805.1 - 0.014 13.9 4.8 0.046 12.1 4.8 1.7 1 1 0 1 1 1 0 Transmembrane secretion effector Mpv17_PMP22 PF04117.12 ORY00805.1 - 0.014 15.6 0.9 0.064 13.5 0.9 2.2 1 0 0 1 1 1 0 Mpv17 / PMP22 family tRNA_synthFbeta PF17759.1 ORY00806.1 - 3.7e-48 163.8 0.0 5.1e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 ORY00806.1 - 2.8e-31 107.6 0.5 6.1e-30 103.3 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 ORY00806.1 - 1e-29 103.4 0.0 2.3e-29 102.3 0.0 1.6 1 1 0 1 1 1 1 B3/4 domain B5 PF03484.15 ORY00806.1 - 1.9e-22 79.3 0.1 2.7e-18 66.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 ORY00806.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Abhydrolase_1 PF00561.20 ORY00807.1 - 3.4e-12 46.6 0.0 4.4e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY00807.1 - 0.00024 21.8 0.0 0.00028 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY00807.1 - 0.00026 20.3 0.0 0.002 17.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY00807.1 - 0.0066 16.3 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase LtrA PF06772.11 ORY00808.1 - 3.3e-72 243.6 26.3 5.8e-71 239.5 26.3 2.5 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) BHD_2 PF10404.9 ORY00810.1 - 0.058 14.4 0.5 2.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF3024 PF11225.8 ORY00811.1 - 0.095 13.0 0.3 7.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Glyco_hydro_59M PF17387.2 ORY00812.1 - 0.072 13.2 1.8 4.4 7.5 0.1 3.0 2 1 1 3 3 3 0 Glycosyl hydrolase family 59 central domain TMEM171 PF15471.6 ORY00816.1 - 1.3 7.9 15.8 2.3 7.2 5.8 2.1 1 1 0 2 2 2 0 Transmembrane protein family 171 ADK PF00406.22 ORY00823.1 - 1.9e-46 157.9 0.0 2.4e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY00823.1 - 4.6e-34 117.8 0.0 6.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY00823.1 - 7e-09 36.3 0.0 1e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY00823.1 - 1.4e-05 25.3 0.0 0.00014 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ORY00823.1 - 0.00052 19.8 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase CoaE PF01121.20 ORY00823.1 - 0.026 14.2 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_19 PF13245.6 ORY00823.1 - 0.038 14.3 0.1 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY00823.1 - 0.07 12.4 0.0 0.092 12.0 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 ORY00823.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 ORY00823.1 - 0.1 12.8 0.0 0.51 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_pol_I_A49 PF06870.12 ORY00824.1 - 1.1e-102 343.8 1.7 1.3e-102 343.5 1.7 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pilosulin PF17499.2 ORY00824.1 - 0.065 13.4 0.4 2.5 8.3 0.2 3.1 3 0 0 3 3 3 0 Ant venom peptides PhoLip_ATPase_C PF16212.5 ORY00825.1 - 1.8e-84 283.4 20.4 1.8e-84 283.4 20.4 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY00825.1 - 1.6e-26 91.8 0.4 1.6e-25 88.6 0.7 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal 2OG-FeII_Oxy_2 PF13532.6 ORY00825.1 - 1.1e-14 55.1 0.0 3.1e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hydrolase PF00702.26 ORY00825.1 - 5.7e-13 49.6 0.2 5.7e-07 30.0 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY00825.1 - 1.9e-12 47.1 0.0 5.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY00825.1 - 3.6e-11 43.0 0.0 1.1e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY00825.1 - 0.00094 19.0 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BCS1_N PF08740.11 ORY00825.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 BCS1 N terminal CPSF73-100_C PF11718.8 ORY00826.1 - 1e-61 208.2 6.4 1.6e-61 207.6 6.4 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 ORY00826.1 - 9.4e-33 112.8 0.0 4.4e-32 110.7 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 ORY00826.1 - 2.6e-21 76.5 0.4 2.6e-21 76.5 0.4 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY00826.1 - 3.3e-19 69.1 0.1 5.7e-18 65.0 0.0 2.7 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 ORY00826.1 - 2.6e-16 59.3 0.0 6.2e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY00826.1 - 2.4e-07 30.5 0.1 8e-07 28.8 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY00826.1 - 2.4e-07 30.8 0.1 1.7e-06 28.1 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORY00826.1 - 8.5e-05 21.9 0.1 0.00018 20.8 0.1 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family U5_2-snRNA_bdg PF10597.9 ORY00826.1 - 0.12 12.5 0.1 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 Acetyltransf_1 PF00583.25 ORY00827.1 - 5.4e-12 46.0 0.0 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY00827.1 - 2.8e-09 37.0 0.0 7.5e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY00827.1 - 1.7e-08 34.7 0.0 4.4e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY00827.1 - 1.5e-06 28.1 0.0 2e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY00827.1 - 0.0001 23.0 0.0 0.00019 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ORY00827.1 - 0.0029 17.8 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY00827.1 - 0.012 15.8 0.1 0.094 12.9 0.0 2.2 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORY00827.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_9 PF13527.7 ORY00827.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.6 ORY00828.1 - 1.2e-13 51.2 7.7 1.7e-13 50.6 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY00828.1 - 3.1e-10 39.7 7.3 5.1e-10 39.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY00828.1 - 4.1e-09 36.6 8.0 6.6e-09 35.9 8.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY00828.1 - 2.9e-08 33.3 8.4 2.9e-08 33.3 8.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY00828.1 - 1.4e-07 31.3 6.1 2.4e-07 30.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY00828.1 - 1.1e-06 28.6 6.4 1.2e-06 28.4 2.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY00828.1 - 3e-06 27.0 8.3 4.5e-06 26.4 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY00828.1 - 1.8e-05 24.6 6.5 1.8e-05 24.6 6.5 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY00828.1 - 2.9e-05 24.0 4.4 4.4e-05 23.5 4.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY00828.1 - 0.00091 19.0 10.9 0.0027 17.5 10.9 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Vps39_2 PF10367.9 ORY00828.1 - 0.014 15.8 0.8 0.014 15.8 0.8 1.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 ORY00828.1 - 0.015 14.9 10.8 0.037 13.6 10.9 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY00828.1 - 0.26 11.5 8.9 16 5.7 8.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 ORY00828.1 - 0.53 10.1 5.2 1.1 9.1 5.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 ORY00828.1 - 0.79 9.7 10.7 1.8 8.6 7.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2175 PF09943.9 ORY00828.1 - 1.5 9.1 5.4 3.2 8.1 5.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) RINGv PF12906.7 ORY00828.1 - 1.8 8.8 8.6 5.3 7.2 8.7 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 ORY00828.1 - 9.1 6.5 9.6 25 5.1 8.4 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING ThiF PF00899.21 ORY00830.1 - 2.3e-42 145.0 0.0 3.8e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORY00830.1 - 4.2e-06 27.0 4.1 1.1e-05 25.6 0.6 3.0 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ORY00830.1 - 0.0026 17.4 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORY00830.1 - 0.0026 18.2 0.1 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ORY00830.1 - 0.0033 16.7 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 ORY00830.1 - 0.047 13.8 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ORY00830.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY00830.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Nuc_sug_transp PF04142.15 ORY00831.1 - 5.1e-114 380.7 15.2 6.2e-114 380.4 15.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORY00831.1 - 5.3e-06 25.9 16.3 2.6e-05 23.6 16.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY00831.1 - 6.2e-05 23.2 34.1 0.0012 19.1 10.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORY00831.1 - 0.00083 18.7 19.3 0.0026 17.0 19.2 2.0 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport YuiB PF14068.6 ORY00831.1 - 0.085 13.4 0.2 0.085 13.4 0.2 2.6 3 0 0 3 3 3 0 Putative membrane protein TPT PF03151.16 ORY00831.1 - 0.092 12.1 16.3 0.13 11.6 11.6 2.7 1 1 2 3 3 3 0 Triose-phosphate Transporter family Tetraspanin PF00335.20 ORY00831.1 - 0.17 11.6 6.9 0.22 11.2 0.7 2.7 2 2 0 2 2 2 0 Tetraspanin family DMT_6 PF04342.12 ORY00831.1 - 2 8.7 7.3 4.3 7.6 0.7 2.8 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Erf4 PF10256.9 ORY00832.1 - 1.4e-27 96.1 0.1 1.8e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Trimer_CC PF08954.11 ORY00832.1 - 0.078 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Trimerisation motif Thiolase_N PF00108.23 ORY00833.1 - 2.1e-84 283.0 0.6 5.5e-84 281.6 0.0 1.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY00833.1 - 2.2e-46 156.5 0.4 5.9e-46 155.1 0.4 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY00833.1 - 4.5e-06 26.4 0.3 1.3e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 ORY00833.1 - 0.1 12.9 0.2 0.42 10.9 0.1 2.1 3 0 0 3 3 3 0 Dodecin ACP_syn_III PF08545.10 ORY00833.1 - 0.13 12.2 1.3 6.5 6.7 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SQS_PSY PF00494.19 ORY00834.1 - 1.5e-45 155.8 0.0 1.7e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase AAA_23 PF13476.6 ORY00835.1 - 2.8e-33 116.1 0.3 4.2e-33 115.5 0.3 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORY00835.1 - 2e-06 27.4 1.0 2.9e-06 26.9 0.1 1.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY00835.1 - 0.0013 18.5 6.8 0.28 10.9 6.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain Ribosomal_L27e PF01777.18 ORY00835.1 - 0.056 13.8 2.7 1.8 9.0 0.2 2.3 2 0 0 2 2 2 0 Ribosomal L27e protein family SMC_N PF02463.19 ORY00836.1 - 7.1e-08 32.1 0.0 8.8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ORY00836.1 - 2.2e-06 27.8 0.0 5.1e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 ORY00836.1 - 0.00015 21.7 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY00836.1 - 0.028 14.2 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain 5_3_exonuc_N PF02739.16 ORY00836.1 - 0.042 13.8 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Mob_Pre PF01076.19 ORY00836.1 - 0.056 13.3 0.1 0.07 12.9 0.1 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme ABC_tran PF00005.27 ORY00836.1 - 0.085 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter BCDHK_Adom3 PF10436.9 ORY00837.1 - 1.9e-44 151.4 0.0 2.6e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY00837.1 - 1.9e-09 38.0 0.0 5.6e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY00837.1 - 0.00041 20.2 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ORY00837.1 - 0.068 13.1 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Ion_trans PF00520.31 ORY00838.1 - 6.9e-06 25.5 9.9 9.2e-06 25.1 9.9 1.1 1 0 0 1 1 1 1 Ion transport protein Vps55 PF04133.14 ORY00838.1 - 0.015 15.3 5.0 0.018 15.0 1.0 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 55 CitMHS PF03600.16 ORY00838.1 - 0.17 11.1 2.3 0.2 10.8 2.3 1.2 1 0 0 1 1 1 0 Citrate transporter DUF2207 PF09972.9 ORY00838.1 - 0.28 9.9 2.2 0.38 9.5 2.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ndc1_Nup PF09531.10 ORY00838.1 - 5.5 5.5 7.8 7.4 5.1 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AC_N PF16214.5 ORY00838.1 - 6 5.9 5.4 7.4 5.6 5.4 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Tetraspanin PF00335.20 ORY00839.1 - 4.1e-13 49.6 3.8 5.7e-13 49.1 3.8 1.2 1 0 0 1 1 1 1 Tetraspanin family PRKCSH-like PF12999.7 ORY00840.1 - 4e-43 147.2 2.1 4e-43 147.2 2.1 2.2 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 ORY00840.1 - 1.7e-30 105.8 0.9 1.7e-30 105.8 0.9 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 ORY00840.1 - 3.7e-08 34.3 3.6 3.7e-08 34.3 3.6 3.0 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein DUF5082 PF16888.5 ORY00840.1 - 0.0032 17.8 11.6 0.051 13.9 1.7 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF5082) Ldl_recept_a PF00057.18 ORY00840.1 - 0.0066 16.6 2.1 0.0066 16.6 2.1 2.9 1 1 1 2 2 2 1 Low-density lipoprotein receptor domain class A Tropomyosin_1 PF12718.7 ORY00840.1 - 0.0093 16.1 7.9 0.0093 16.1 7.9 3.3 3 1 0 3 3 3 1 Tropomyosin like DUF4525 PF15027.6 ORY00840.1 - 0.065 13.0 0.5 0.19 11.5 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4525) MAD PF05557.13 ORY00840.1 - 0.1 11.0 11.6 0.83 7.9 0.1 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Allexi_40kDa PF05549.11 ORY00840.1 - 0.15 11.6 2.2 0.29 10.6 2.2 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein V_ATPase_I PF01496.19 ORY00840.1 - 0.46 8.3 5.9 0.64 7.9 5.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.9 ORY00840.1 - 0.71 9.8 11.1 2.1 8.2 7.1 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.6 ORY00840.1 - 0.78 10.2 9.7 11 6.5 0.7 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 ORY00840.1 - 1.1 9.5 8.9 0.35 11.0 5.5 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MerR-DNA-bind PF09278.11 ORY00840.1 - 1.1 9.8 9.0 4.5 7.9 0.5 3.2 3 0 0 3 3 3 0 MerR, DNA binding Fmp27_WPPW PF10359.9 ORY00840.1 - 2.3 7.0 11.7 0.42 9.4 8.1 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FlxA PF14282.6 ORY00840.1 - 2.6 8.1 11.1 5.3 7.1 0.5 3.1 2 1 1 3 3 3 0 FlxA-like protein TPR_MLP1_2 PF07926.12 ORY00840.1 - 2.9 8.0 14.8 3.1 7.9 8.3 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 ORY00840.1 - 3.3 8.5 11.7 0.37 11.6 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF2203 PF09969.9 ORY00840.1 - 3.8 8.3 9.8 0.4 11.4 3.8 2.4 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) BRI3BP PF14965.6 ORY00840.1 - 5.2 6.6 4.6 50 3.4 0.0 2.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 GreA_GreB_N PF03449.15 ORY00840.1 - 6.2 7.1 13.9 4.3 7.6 0.8 4.1 3 1 0 3 3 3 0 Transcription elongation factor, N-terminal EAP30 PF04157.16 ORY00841.1 - 1.1e-76 257.2 0.1 1.3e-76 257.0 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family ZapD PF07072.11 ORY00841.1 - 0.077 12.7 3.2 0.7 9.6 0.3 2.7 2 1 1 3 3 3 0 Cell division protein Protoglobin PF11563.8 ORY00841.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Protoglobin TrmB PF01978.19 ORY00841.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Spore_III_AB PF09548.10 ORY00841.1 - 0.26 11.4 2.1 0.36 10.9 0.4 2.0 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Dickkopf_N PF04706.12 ORY00842.1 - 5.5e-15 55.6 168.0 0.0075 16.7 9.0 11.3 11 0 0 11 11 11 10 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 ORY00842.1 - 4.6e-07 29.8 195.0 0.029 14.5 14.4 11.1 1 1 10 11 11 11 10 I2-superfamily conotoxins UPF0506 PF11703.8 ORY00842.1 - 0.0014 19.0 161.3 0.085 13.3 25.2 6.9 1 1 7 9 9 9 8 UPF0506 BCDHK_Adom3 PF10436.9 ORY00843.1 - 7.2e-08 32.4 0.8 1.1e-07 31.9 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY00843.1 - 1.2e-07 32.2 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PP2C PF00481.21 ORY00844.1 - 3.5e-82 275.9 0.0 4.5e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C TERB2 PF15101.6 ORY00845.1 - 3.1e-09 37.2 1.8 1.6e-08 34.9 1.8 1.9 1 1 0 1 1 1 1 Telomere-associated protein TERB2 BRCT_2 PF16589.5 ORY00845.1 - 0.00034 21.0 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Yae1_N PF09811.9 ORY00846.1 - 5e-05 22.9 25.9 0.079 12.7 10.7 3.6 1 1 2 3 3 3 3 Essential protein Yae1, N terminal Yae1_N PF09811.9 ORY00847.1 - 0.0012 18.5 26.8 0.0065 16.2 1.5 4.2 3 1 1 5 5 5 3 Essential protein Yae1, N terminal HA1 PF18239.1 ORY00847.1 - 1.3 9.0 4.0 11 6.0 0.3 2.7 1 1 1 2 2 2 0 Hemagglutinin I LRR_6 PF13516.6 ORY00849.1 - 3.1e-13 48.6 2.6 9.7e-05 22.1 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich repeat F-box-like PF12937.7 ORY00849.1 - 1.4e-12 47.3 0.7 3.2e-12 46.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY00849.1 - 3.6e-09 36.7 1.8 0.025 15.0 0.0 3.6 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY00849.1 - 1.4e-05 24.8 0.0 4.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY00849.1 - 0.052 14.1 6.1 1.2e+02 3.9 0.5 5.3 4 1 1 5 5 5 0 Leucine Rich Repeat Cyclin PF08613.11 ORY00850.1 - 3.5e-08 34.0 0.1 3.6e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY00850.1 - 6.6e-06 25.9 0.0 8.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAM2 PF07145.15 ORY00851.1 - 0.015 15.0 6.9 1 9.2 0.0 4.0 4 0 0 4 4 4 0 Ataxin-2 C-terminal region GSDH PF07995.11 ORY00851.1 - 0.04 13.2 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Acyl-CoA_dh_1 PF00441.24 ORY00852.1 - 4.9e-52 176.1 3.9 4.9e-52 176.1 3.9 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY00852.1 - 1.9e-28 99.4 0.3 4.3e-28 98.2 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY00852.1 - 1.1e-27 96.0 0.2 2.4e-27 95.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY00852.1 - 4.8e-20 72.2 1.8 8.5e-20 71.4 1.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY00852.1 - 0.037 13.7 0.0 0.096 12.3 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PCRF PF03462.18 ORY00854.1 - 9e-57 192.1 0.3 9e-57 192.1 0.3 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ORY00854.1 - 6.8e-42 142.1 2.7 6.8e-42 142.1 2.7 1.7 2 0 0 2 2 2 1 RF-1 domain GCOM2 PF15328.6 ORY00855.1 - 0.015 15.7 13.3 0.025 14.9 13.3 1.4 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 HTH_12 PF08461.10 ORY00855.1 - 0.7 9.9 3.3 0.83 9.6 0.2 2.5 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain HMG_box PF00505.19 ORY00856.1 - 0.036 14.5 1.1 0.11 13.0 1.1 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box Jagunal PF07086.12 ORY00857.1 - 0.075 13.1 4.8 0.11 12.6 4.6 1.5 1 1 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis Tetraspanin PF00335.20 ORY00857.1 - 3.6 7.3 11.9 7.6 6.2 11.6 1.7 1 1 0 1 1 1 0 Tetraspanin family HMG_box PF00505.19 ORY00858.1 - 0.025 15.0 0.7 0.06 13.8 0.7 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box DUF996 PF06195.13 ORY00859.1 - 0.0017 18.6 4.1 0.0021 18.4 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF996) Marek_SORF3 PF07153.11 ORY00859.1 - 0.015 14.6 0.5 0.017 14.5 0.5 1.1 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein DUF4199 PF13858.6 ORY00859.1 - 0.058 13.8 3.8 0.071 13.5 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Tetraspanin PF00335.20 ORY00859.1 - 0.57 9.8 6.5 6.6 6.4 6.5 2.0 1 1 0 1 1 1 0 Tetraspanin family Pox_A14 PF05767.12 ORY00859.1 - 5.4 7.2 9.0 20 5.4 9.0 1.8 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 Myb_DNA-bind_4 PF13837.6 ORY00860.1 - 1.1e-16 60.9 3.9 1.1e-16 60.9 3.9 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY00860.1 - 2.1e-07 31.0 2.0 3.9e-07 30.1 1.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY00860.1 - 1.4e-05 25.3 1.2 4.7e-05 23.6 1.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY00860.1 - 0.0017 18.6 2.7 0.0017 18.6 2.7 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORY00860.1 - 0.016 16.1 1.7 0.016 16.1 1.7 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY00860.1 - 0.018 15.3 0.2 0.041 14.1 0.2 1.8 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Jak1_Phl PF17887.1 ORY00860.1 - 0.023 14.7 4.6 0.085 12.8 0.2 2.3 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain NinB PF05772.12 ORY00860.1 - 0.023 14.5 0.5 0.059 13.2 0.5 1.6 1 0 0 1 1 1 0 NinB protein HEAT PF02985.22 ORY00861.1 - 1e-18 65.8 13.8 0.0026 17.9 0.0 11.4 12 0 0 12 12 11 3 HEAT repeat HEAT_EZ PF13513.6 ORY00861.1 - 1.9e-17 63.4 7.7 4e-11 43.2 0.0 7.8 8 3 2 10 10 10 2 HEAT-like repeat IBN_N PF03810.19 ORY00861.1 - 3.1e-12 46.2 1.4 2e-10 40.5 0.5 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 ORY00861.1 - 1.2e-11 44.8 7.2 0.03 14.7 0.0 6.6 4 2 4 8 8 8 5 HEAT repeats Arm PF00514.23 ORY00861.1 - 1.9e-07 30.9 2.7 0.028 14.5 0.0 6.6 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 ORY00861.1 - 5.1e-05 23.2 11.0 1.4 8.8 0.1 5.8 4 3 2 6 6 6 4 Domain of unknown function (DUF3385) RIX1 PF08167.12 ORY00861.1 - 0.00038 20.2 8.2 6.9 6.4 0.0 5.5 5 2 1 6 6 6 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 ORY00861.1 - 0.0011 19.6 0.3 0.52 10.9 0.0 5.0 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 ORY00861.1 - 0.0027 17.3 1.4 4.5 6.8 0.1 4.2 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II TIP120 PF08623.10 ORY00861.1 - 0.044 13.6 4.1 0.38 10.5 0.0 3.8 3 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) TAF6_C PF07571.13 ORY00861.1 - 0.053 13.8 0.1 2.3 8.6 0.1 3.5 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Ribosomal_S2 PF00318.20 ORY00862.1 - 7.1e-63 211.7 0.4 6e-37 127.0 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S2 DUF1746 PF08508.10 ORY00862.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) Beta-Casp PF10996.8 ORY00863.1 - 7.8e-09 35.8 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 ORY00863.1 - 3.7e-08 33.0 0.0 5.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORY00863.1 - 0.00049 19.4 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Glyco_hydro_3 PF00933.21 ORY00864.1 - 1.5e-84 284.1 0.0 2.1e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 ORY00864.1 - 1.5e-14 54.3 0.0 9.3e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY00864.1 - 6.1e-10 39.4 0.0 0.002 18.5 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY00864.1 - 1.4e-09 38.1 0.0 0.0014 18.7 0.1 2.9 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 ORY00864.1 - 1.6e-08 34.7 0.0 6.3e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.7 ORY00864.1 - 2e-07 31.0 0.1 0.0014 18.6 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY00864.1 - 0.078 13.1 0.3 14 5.9 0.0 2.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase ATG22 PF11700.8 ORY00865.1 - 1.5e-108 363.5 22.5 1.7e-108 363.3 22.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY00865.1 - 2.7e-12 46.3 37.3 8.9e-09 34.7 18.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SLATT_1 PF18181.1 ORY00865.1 - 0.49 10.3 2.5 0.99 9.3 0.3 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 HTH_16 PF12645.7 ORY00866.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Ribonuclease_T2 PF00445.18 ORY00867.1 - 3.8e-36 125.0 0.0 5.7e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4646 PF15496.6 ORY00911.1 - 2.6e-25 89.5 0.1 4.7e-25 88.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) p450 PF00067.22 ORY00912.1 - 1.8e-62 211.6 0.0 2.3e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_13 PF13880.6 ORY00913.1 - 2.2e-28 98.0 0.1 3.7e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 ORY00913.1 - 1.8e-16 59.6 0.4 3.5e-16 58.8 0.4 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 ORY00913.1 - 0.00049 20.5 0.1 0.0025 18.2 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY00913.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY00913.1 - 0.027 14.4 0.0 0.069 13.1 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2226 PF09987.9 ORY00913.1 - 0.035 13.5 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Ferredoxin_N PF16947.5 ORY00913.1 - 0.037 14.1 0.1 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Acetyltransf_15 PF17013.5 ORY00913.1 - 0.044 13.2 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Actin PF00022.19 ORY00914.1 - 4.2e-150 499.9 0.0 1.4e-149 498.1 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 ORY00914.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain PseudoU_synth_2 PF00849.22 ORY00915.1 - 1.8e-30 106.1 0.2 2.6e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ORY00915.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain NLE PF08154.12 ORY00915.1 - 0.14 12.7 0.2 1 10.0 0.0 2.1 2 0 0 2 2 2 0 NLE (NUC135) domain EF-hand_1 PF00036.32 ORY00916.1 - 2.3e-26 89.3 16.3 3.2e-06 26.3 0.4 5.9 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 ORY00916.1 - 1.4e-23 80.8 8.1 5.4e-06 25.9 0.1 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 ORY00916.1 - 2e-23 82.6 6.1 1.1e-09 38.6 0.5 3.1 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 ORY00916.1 - 5.7e-19 67.7 5.7 1.1e-10 41.1 0.1 3.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORY00916.1 - 3.3e-15 54.8 11.1 3.7e-05 23.0 0.0 5.1 5 0 0 5 5 5 4 EF hand Anoctamin PF04547.12 ORY00917.1 - 4.2e-91 306.0 19.8 5.1e-91 305.8 19.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel MARVEL PF01284.23 ORY00917.1 - 0.0056 16.7 4.2 0.0056 16.7 4.2 2.8 3 0 0 3 3 3 1 Membrane-associating domain zf-H2C2_2 PF13465.6 ORY00918.1 - 5.4e-09 36.1 10.7 1.8e-06 28.1 1.3 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY00918.1 - 7.1e-08 32.5 16.6 0.00022 21.5 2.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY00918.1 - 2.3e-06 27.9 12.9 0.0043 17.8 1.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORY00918.1 - 7.7e-05 22.9 2.8 0.00016 21.9 1.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY00918.1 - 0.0054 16.7 1.3 0.0054 16.7 1.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY00918.1 - 0.0089 16.3 1.9 0.023 15.0 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY00918.1 - 0.46 10.3 5.9 1.7 8.4 0.3 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type BCAS3 PF12490.8 ORY00920.1 - 0.23 11.0 1.2 2 7.9 0.3 2.4 1 1 0 2 2 2 0 Breast carcinoma amplified sequence 3 Cation_efflux PF01545.21 ORY00921.1 - 1.7e-27 96.4 0.0 1.7e-27 96.4 0.0 2.4 3 1 0 3 3 3 1 Cation efflux family HPP PF04982.13 ORY00921.1 - 2.8e-27 95.3 4.0 8e-27 93.8 4.0 1.7 1 0 0 1 1 1 1 HPP family AAA_lid_2 PF17863.1 ORY00921.1 - 1.7e-05 24.5 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain DMPK_coil PF08826.10 ORY00921.1 - 0.08 13.1 0.3 0.19 11.9 0.3 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like Metallopep PF12044.8 ORY00922.1 - 1.2e-133 445.8 0.0 1.6e-133 445.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 ORY00922.1 - 3.7e-07 30.2 0.0 1e-06 28.7 0.0 1.8 1 1 1 2 2 2 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 ORY00922.1 - 0.04 13.8 0.1 0.5 10.2 0.1 2.4 3 0 0 3 3 3 0 Matrixin Reprolysin_3 PF13582.6 ORY00922.1 - 0.14 12.7 0.2 0.35 11.4 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.25 ORY00923.1 - 6.3e-58 196.2 0.0 9.3e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY00923.1 - 3e-27 95.6 0.0 6.5e-27 94.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY00923.1 - 5.9e-08 32.4 0.0 9.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY00923.1 - 0.00057 18.8 0.0 0.0017 17.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY00923.1 - 0.00082 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY00923.1 - 0.0012 18.8 0.3 0.62 9.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY00923.1 - 0.0025 16.8 0.1 0.007 15.3 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY00923.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Methyltransf_10 PF05971.12 ORY00924.1 - 6.1e-56 190.0 0.0 7.5e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 ORY00924.1 - 0.00078 19.0 0.0 0.0063 16.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.16 ORY00924.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 ORY00924.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY00924.1 - 0.19 12.5 0.0 0.48 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L11_N PF03946.14 ORY00925.1 - 1.5e-24 85.6 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY00925.1 - 3e-17 62.9 0.2 6.2e-17 61.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain NuA4 PF09340.10 ORY00926.1 - 4.8e-22 77.6 3.2 1.3e-21 76.2 3.2 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Phage_int_SAM_5 PF13102.6 ORY00926.1 - 0.071 13.4 6.6 0.21 12.0 1.9 2.8 1 1 1 2 2 2 0 Phage integrase SAM-like domain Lipoprotein_20 PF13942.6 ORY00926.1 - 0.48 10.3 7.2 0.1 12.5 0.9 2.1 2 1 0 2 2 2 0 YfhG lipoprotein PBECR5 PF18814.1 ORY00926.1 - 1.6 8.6 10.8 6.7 6.6 10.8 1.8 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 SPATA3 PF15662.5 ORY00926.1 - 6 7.4 9.5 1 10.0 6.0 1.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family DUF4878 PF12870.7 ORY00926.1 - 8.4 6.7 8.6 2.7 8.4 1.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4878) DEAD PF00270.29 ORY00927.1 - 2e-45 154.7 0.3 3.5e-45 153.9 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY00927.1 - 2.4e-33 114.8 0.1 1.1e-32 112.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 ORY00927.1 - 6e-05 23.4 0.0 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY00927.1 - 7.7e-05 22.8 0.0 0.00017 21.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY00927.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 ORY00927.1 - 0.016 14.0 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 ORY00927.1 - 0.049 13.6 0.6 0.2 11.6 0.1 2.4 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 ORY00927.1 - 0.12 12.7 0.6 0.56 10.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 ORY00927.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Helicase GNT-I PF03071.15 ORY00928.1 - 2.8e-16 59.3 0.5 3.5e-16 59.0 0.5 1.0 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 ORY00928.1 - 1.8e-08 33.9 0.0 8.6e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 ORY00928.1 - 0.053 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 HSP20 PF00011.21 ORY00930.1 - 3.5e-11 43.1 0.4 5e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY00930.1 - 5.8e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA ESPR PF13018.6 ORY00931.1 - 0.092 12.6 0.7 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system Cyclin PF08613.11 ORY00932.1 - 1e-10 42.2 0.0 1.5e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY00932.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Prenylcys_lyase PF07156.14 ORY00933.1 - 1.6e-63 215.0 3.9 8.7e-62 209.3 3.9 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 ORY00933.1 - 9e-16 58.2 0.0 4e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY00933.1 - 3.4e-13 49.6 1.0 7.1e-12 45.4 1.0 2.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY00933.1 - 0.0007 18.9 0.1 0.0025 17.1 0.0 1.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY00933.1 - 0.012 15.2 0.0 0.098 12.2 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Sugar_tr PF00083.24 ORY00934.1 - 2.9e-108 362.7 11.3 3.7e-108 362.3 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY00934.1 - 4.5e-30 104.8 19.4 4.5e-30 104.8 19.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 ORY00934.1 - 0.0064 14.9 9.5 0.31 9.4 4.7 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector DUF1378 PF07125.11 ORY00934.1 - 0.098 12.8 0.2 9.3 6.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Acetyltransf_1 PF00583.25 ORY00935.1 - 2.4e-12 47.1 0.0 3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY00935.1 - 1.5e-09 38.1 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY00935.1 - 2.3e-08 34.0 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY00935.1 - 2.3e-07 30.7 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY00935.1 - 0.0026 17.9 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ORY00935.1 - 0.055 14.1 0.0 0.067 13.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SPA PF08616.10 ORY00936.1 - 9.6e-39 131.9 0.0 1.9e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 ORY00936.1 - 2e-18 67.1 6.5 4.2e-18 66.1 0.0 3.1 3 1 1 4 4 4 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 ORY00936.1 - 5.2e-09 35.3 0.0 0.00037 19.3 0.0 2.9 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 ORY00936.1 - 1e-07 31.8 0.0 0.0061 16.2 0.0 2.5 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) Alpha_L_fucos PF01120.17 ORY00936.1 - 0.025 14.0 0.7 0.053 13.0 0.4 1.5 2 0 0 2 2 2 0 Alpha-L-fucosidase CsbD PF05532.12 ORY00937.1 - 5.9e-14 51.7 17.7 6.8e-07 29.1 0.4 3.0 2 1 1 3 3 3 2 CsbD-like Peptidase_M17 PF00883.21 ORY00938.1 - 8.1e-63 212.6 0.0 9.9e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Enterotoxin_b PF01376.18 ORY00938.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain Alpha-amylase_C PF02806.18 ORY00939.1 - 7.9e-26 90.4 0.1 2.8e-25 88.6 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 ORY00939.1 - 3.5e-18 65.7 0.0 7.4e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY00939.1 - 1.5e-17 64.2 0.1 8.5e-13 48.6 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Arrestin_C PF02752.22 ORY00940.1 - 8e-13 49.0 0.1 9e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY00940.1 - 9.3e-06 25.8 0.1 2.8e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY00940.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like AAA PF00004.29 ORY00941.1 - 1.5e-43 148.4 0.0 2.4e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY00941.1 - 5.8e-26 90.3 0.1 1.8e-25 88.7 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORY00941.1 - 1.1e-24 86.2 4.9 2.7e-24 85.0 4.9 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORY00941.1 - 8.2e-08 31.9 0.0 2.5e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY00941.1 - 6.9e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY00941.1 - 1.9e-05 25.1 0.0 0.0018 18.7 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY00941.1 - 2.6e-05 24.3 0.0 0.0001 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY00941.1 - 4.8e-05 22.7 0.0 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 ORY00941.1 - 6.1e-05 23.1 0.0 0.00023 21.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ORY00941.1 - 7.2e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ORY00941.1 - 7.2e-05 23.1 0.1 0.0067 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY00941.1 - 0.00035 19.8 0.0 0.00065 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY00941.1 - 0.00036 20.9 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 ORY00941.1 - 0.00051 20.6 0.1 0.002 18.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 ORY00941.1 - 0.00083 19.5 0.0 0.0026 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY00941.1 - 0.0014 18.8 0.1 0.0053 16.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 ORY00941.1 - 0.0029 17.4 0.3 0.01 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY00941.1 - 0.009 16.4 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain USP8_dimer PF08969.11 ORY00941.1 - 0.023 14.9 5.2 0.049 13.8 5.2 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_25 PF13481.6 ORY00941.1 - 0.026 14.1 0.1 0.73 9.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY00941.1 - 0.029 13.9 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY00941.1 - 0.038 13.4 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY00941.1 - 0.043 13.7 0.0 0.73 9.7 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 ORY00941.1 - 0.059 12.5 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 ORY00941.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin TniB PF05621.11 ORY00941.1 - 0.068 12.6 0.0 14 5.0 0.0 2.6 1 1 0 2 2 2 0 Bacterial TniB protein DUF3543 PF12063.8 ORY00941.1 - 0.069 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) PhoH PF02562.16 ORY00941.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ORY00941.1 - 0.079 12.3 0.1 9 5.6 0.0 2.3 1 1 1 2 2 2 0 KaiC CPT PF07931.12 ORY00941.1 - 0.089 12.6 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 ORY00941.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORY00941.1 - 0.16 11.6 0.0 0.53 10.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 ORY00941.1 - 0.37 10.7 3.0 1.8 8.4 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TPR_2 PF07719.17 ORY00941.1 - 1.1 9.6 3.7 1.8 8.8 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat LPMO_10 PF03067.15 ORY00942.1 - 0.00032 21.4 0.1 0.0007 20.3 0.1 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY00942.1 - 0.0016 18.4 0.2 0.63 10.0 0.0 2.3 1 1 0 2 2 2 2 Glycosyl hydrolase family 61 Mo-co_dimer PF03404.16 ORY00942.1 - 0.0068 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain AAA PF00004.29 ORY00989.1 - 2.8e-17 63.4 0.1 7.4e-16 58.8 0.0 3.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY00989.1 - 2.2e-07 31.4 0.0 9.1e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY00989.1 - 0.00041 20.1 0.0 0.0021 17.8 0.0 2.1 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY00989.1 - 0.00085 19.3 0.0 0.0031 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY00989.1 - 0.00095 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 ORY00989.1 - 0.0028 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY00989.1 - 0.0032 18.0 0.3 0.015 15.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY00989.1 - 0.0034 17.7 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY00989.1 - 0.006 17.0 0.0 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 ORY00989.1 - 0.009 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 ORY00989.1 - 0.052 13.5 0.0 0.36 10.7 0.0 2.3 3 0 0 3 3 3 0 NACHT domain ATPase PF06745.13 ORY00989.1 - 0.054 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 ORY00989.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORY00989.1 - 0.072 12.9 1.0 0.29 10.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 ORY00989.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY00989.1 - 0.15 12.1 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-ZPR1 PF03367.13 ORY00990.1 - 9.2e-11 41.8 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 ZPR1 zinc-finger domain DUF3014 PF11219.8 ORY00990.1 - 0.044 14.0 0.1 0.078 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Pox_P21 PF05313.12 ORY00991.1 - 0.032 13.8 0.2 0.038 13.6 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Cad PF03596.13 ORY00991.1 - 0.047 13.6 2.0 0.053 13.4 2.0 1.1 1 0 0 1 1 1 0 Cadmium resistance transporter DUF2518 PF10726.9 ORY00991.1 - 0.088 12.5 0.3 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of function (DUF2518) DUF5090 PF17009.5 ORY00991.1 - 0.33 10.9 4.0 0.36 10.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF4191 PF13829.6 ORY00991.1 - 7.6 5.8 6.5 8.9 5.6 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PBD PF00786.28 ORY00992.1 - 1.3e-16 60.7 0.7 9.4e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 P21-Rho-binding domain WD40 PF00400.32 ORY00993.1 - 7.2e-29 99.4 5.1 5.6e-06 27.0 0.0 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Bromodomain PF00439.25 ORY00993.1 - 3.3e-13 49.5 0.1 1e-12 47.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 ORY00993.1 - 5.9e-11 42.5 0.2 0.0032 17.7 0.1 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY00993.1 - 0.0006 18.9 1.0 0.75 8.7 0.0 3.8 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY00993.1 - 0.0042 15.8 0.0 0.082 11.5 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nse4-Nse3_bdg PF15412.6 ORY00993.1 - 0.0093 16.1 0.2 0.15 12.2 0.0 2.9 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE YL1 PF05764.13 ORY00993.1 - 0.011 15.9 73.1 0.14 12.3 15.9 3.1 2 1 1 3 3 3 0 YL1 nuclear protein DUF5641 PF18701.1 ORY00993.1 - 0.1 12.8 0.1 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Shugoshin_N PF07558.11 ORY00994.1 - 0.024 14.5 1.5 0.19 11.6 0.3 2.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region LppA PF16708.5 ORY00994.1 - 0.082 12.8 7.3 5.6 6.9 0.0 3.5 1 1 3 4 4 4 0 Lipoprotein confined to pathogenic Mycobacterium CRISPR_Cas2 PF09827.9 ORY00994.1 - 0.09 13.0 1.4 11 6.2 0.0 3.3 3 1 0 3 3 3 0 CRISPR associated protein Cas2 DUF2730 PF10805.8 ORY00994.1 - 1.5 8.9 8.4 4.3 7.5 5.3 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) AMP-binding PF00501.28 ORY00995.1 - 3.2e-66 223.7 0.0 1.5e-38 132.5 0.0 3.7 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 ORY00995.1 - 1.9e-12 48.0 0.1 1.2e-11 45.4 0.0 2.2 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 ORY00995.1 - 3e-05 23.9 0.1 6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Gas vesicle protein G DEAD PF00270.29 ORY00996.1 - 9.4e-48 162.3 0.0 1.3e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY00996.1 - 1.4e-30 105.8 0.0 4.8e-28 97.7 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY00996.1 - 0.00011 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit 2-Hacid_dh_C PF02826.19 ORY00998.1 - 1.1e-51 174.7 0.0 1.9e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY00998.1 - 1.1e-36 125.4 0.0 1.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY00998.1 - 2.3e-07 31.1 1.0 6.8e-07 29.6 0.0 2.2 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 ORY00998.1 - 0.0088 15.8 0.1 0.03 14.1 0.1 2.0 1 1 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 ORY00998.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 ORY00998.1 - 0.015 14.8 0.1 0.38 10.3 0.0 2.4 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 ORY00998.1 - 0.033 14.7 0.0 0.21 12.1 0.0 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 ORY00998.1 - 0.033 14.1 1.0 1 9.2 0.2 2.9 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CBM_11 PF03425.13 ORY00999.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) DUF4041 PF13250.6 ORY00999.1 - 0.37 10.7 1.5 0.93 9.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) DZR PF12773.7 ORY01000.1 - 0.02 14.9 0.9 0.059 13.4 0.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 ORY01000.1 - 0.025 14.6 0.5 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-LITAF-like PF10601.9 ORY01000.1 - 0.027 14.7 1.2 0.054 13.8 1.2 1.5 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain DUF4451 PF14616.6 ORY01000.1 - 0.041 14.1 0.3 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PriA_CRR PF18319.1 ORY01000.1 - 0.12 12.4 0.2 0.12 12.4 0.2 1.8 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Zn_ribbon_SprT PF17283.2 ORY01000.1 - 0.13 12.2 0.6 21 5.1 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 ORY01000.1 - 0.14 11.8 0.7 6.6 6.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_20 PF00728.22 ORY01001.1 - 1.8e-38 132.9 0.0 2.3e-37 129.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY01001.1 - 1.6e-11 45.1 0.0 2.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cyclin PF08613.11 ORY01002.1 - 5.8e-12 46.3 0.0 7.8e-12 45.9 0.0 1.3 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY01002.1 - 2.1e-06 27.5 0.0 2.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pox_MCEL PF03291.16 ORY01003.1 - 3.1e-95 319.1 0.8 6.8e-95 318.0 0.8 1.5 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 ORY01003.1 - 1e-14 55.0 0.0 1.8e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY01003.1 - 2.5e-11 43.6 0.0 4.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY01003.1 - 7.9e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY01003.1 - 1.9e-09 38.1 0.0 3.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY01003.1 - 4.2e-09 37.1 0.0 8.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORY01003.1 - 0.00069 18.9 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 ORY01003.1 - 0.00094 18.6 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY01003.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 ORY01003.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 ORY01003.1 - 0.01 15.2 0.9 0.04 13.2 0.9 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 ORY01003.1 - 0.015 14.9 0.6 0.063 12.9 0.2 2.3 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW PrmA PF06325.13 ORY01003.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ORY01003.1 - 0.089 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 ORY01003.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Adap_comp_sub PF00928.21 ORY01004.1 - 3.4e-86 288.9 0.3 4.2e-86 288.6 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY01004.1 - 2.1e-06 27.7 0.9 3.8e-06 26.9 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 ORY01004.1 - 0.0099 15.4 0.2 0.019 14.4 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PCMD PF13201.6 ORY01004.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative carbohydrate metabolism domain HECT PF00632.25 ORY01005.1 - 1.1e-79 268.2 0.1 2.5e-79 267.0 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 ORY01005.1 - 0.00046 20.1 0.8 1.3 9.2 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY01005.1 - 0.011 16.0 2.6 1 9.8 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 ORY01005.1 - 0.012 16.2 0.0 0.24 11.9 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat FAM72 PF14976.6 ORY01006.1 - 8.1e-30 103.9 3.5 9.8e-30 103.6 3.5 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORY01006.1 - 0.13 12.5 9.9 0.48 10.7 10.0 1.9 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PHO4 PF01384.20 ORY01007.1 - 8.9e-116 386.6 15.8 1e-115 386.4 15.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF4149 PF13664.6 ORY01007.1 - 3 8.2 10.4 0.045 14.1 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) PHO4 PF01384.20 ORY01008.1 - 5.9e-116 387.2 15.2 6.8e-116 387.0 15.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF4149 PF13664.6 ORY01008.1 - 6.8 7.1 10.1 0.11 12.9 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) COX6B PF02297.17 ORY01009.1 - 6.1e-12 45.6 0.8 7.8e-12 45.3 0.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Y_phosphatase2 PF03162.13 ORY01010.1 - 4.1e-62 208.6 0.1 4.5e-62 208.5 0.1 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY01010.1 - 2.9e-06 27.4 0.0 4.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY01010.1 - 3.6e-05 23.6 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY01010.1 - 0.03 13.9 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Dfp1_Him1_M PF08630.10 ORY01011.1 - 2.3e-22 79.5 0.0 5.8e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 ORY01011.1 - 6e-16 58.3 0.7 1.4e-15 57.1 0.7 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 ORY01011.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY01011.1 - 0.00082 19.3 0.0 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 ORY01011.1 - 0.002 18.5 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain FYDLN_acid PF09538.10 ORY01011.1 - 0.042 14.5 1.1 0.13 12.9 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PMAIP1 PF15150.6 ORY01011.1 - 0.14 12.1 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced Ribosomal_L27 PF01016.19 ORY01012.1 - 2.2e-37 126.9 0.4 3e-37 126.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein C2 PF00168.30 ORY01013.1 - 2.5e-103 339.3 10.5 1.4e-21 76.7 0.0 6.3 6 0 0 6 6 6 6 C2 domain CC2D2AN-C2 PF15625.6 ORY01013.1 - 0.028 14.1 0.6 16 5.2 0.1 3.3 3 0 0 3 3 3 0 CC2D2A N-terminal C2 domain NT-C2 PF10358.9 ORY01013.1 - 0.033 13.9 2.8 9.6 5.9 0.0 4.0 4 0 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_1 PF00515.28 ORY01014.1 - 2.7e-08 33.3 14.2 0.023 14.5 1.7 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY01014.1 - 3.7e-05 24.1 0.8 0.083 13.4 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY01014.1 - 4.4e-05 23.3 9.0 0.4 10.9 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY01014.1 - 0.0001 22.5 4.3 0.003 17.8 0.2 2.7 1 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY01014.1 - 0.014 15.6 5.4 0.014 15.6 5.4 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY01014.1 - 0.016 15.2 3.0 0.25 11.5 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-UBR PF02207.20 ORY01014.1 - 0.018 15.2 0.5 0.043 14.0 0.5 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TarS_C1 PF18674.1 ORY01014.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 GvpL_GvpF PF06386.11 ORY01014.1 - 0.053 13.5 1.8 0.087 12.7 1.8 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF MIT PF04212.18 ORY01014.1 - 0.12 12.5 10.1 0.69 10.0 0.1 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Atrophin-1 PF03154.15 ORY01014.1 - 5.6 5.1 7.2 7.5 4.7 7.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Serinc PF03348.15 ORY01015.1 - 1.2e-147 492.3 18.5 1.5e-147 492.0 18.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) AcetylCoA_hyd_C PF13336.6 ORY01016.1 - 2.5e-60 202.9 0.0 4.3e-60 202.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 ORY01016.1 - 2.1e-25 89.9 0.0 3.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.22 ORY01016.1 - 0.00076 19.4 0.0 0.0059 16.6 0.0 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain Glyco_transf_34 PF05637.12 ORY01017.1 - 5.8e-43 147.3 1.7 1.9e-40 139.1 1.7 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY01017.1 - 0.0033 17.4 0.2 0.005 16.9 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 ORY01017.1 - 0.004 16.7 0.0 0.0091 15.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF273 RrnaAD PF00398.20 ORY01018.1 - 6.5e-66 222.1 0.0 8.4e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ORY01018.1 - 5.6e-05 23.8 0.0 0.00012 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY01018.1 - 0.00061 19.6 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 ORY01018.1 - 0.0019 18.8 0.0 0.004 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY01018.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORY01018.1 - 0.0097 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 ORY01018.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 ORY01018.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 ORY01018.1 - 0.14 11.8 0.1 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 ORY01018.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 ORY01019.1 - 9.9e-129 419.5 29.5 1.4e-14 54.0 0.0 16.9 4 1 14 18 18 17 17 PPR repeat family PPR PF01535.20 ORY01019.1 - 2.1e-94 303.4 18.5 6.2e-09 35.5 0.1 17.6 18 0 0 18 18 18 14 PPR repeat PPR_1 PF12854.7 ORY01019.1 - 1.2e-85 280.8 3.7 8.6e-09 35.0 0.0 16.0 17 0 0 17 17 16 12 PPR repeat PPR_3 PF13812.6 ORY01019.1 - 1.5e-84 278.0 8.2 3.1e-13 49.6 0.0 11.9 7 4 6 14 14 14 10 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY01019.1 - 3.1e-59 199.9 4.7 4.4e-15 55.6 0.0 7.6 1 1 6 7 7 7 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORY01019.1 - 3.5e-16 59.7 8.4 0.00061 20.2 0.6 8.8 4 2 2 6 6 6 3 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORY01019.1 - 2.2e-08 33.4 7.9 0.41 9.4 0.0 6.1 1 1 4 6 6 6 3 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.11 ORY01019.1 - 3.1e-06 26.5 5.8 0.092 11.8 0.2 5.7 1 1 4 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.6 ORY01019.1 - 7.4e-06 26.4 0.0 66 4.7 0.0 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY01019.1 - 0.0014 18.5 0.4 15 5.9 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY01019.1 - 0.0021 17.8 1.7 1.2 9.1 0.1 4.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY01019.1 - 0.0091 16.0 2.1 2.5 8.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 ORY01019.1 - 0.015 15.0 1.8 47 3.6 0.0 5.2 5 2 0 5 5 5 0 26S proteasome subunit RPN7 Coatomer_E PF04733.14 ORY01019.1 - 0.065 12.6 0.0 1.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Coatomer epsilon subunit Condensin2nSMC PF12422.8 ORY01019.1 - 0.38 10.9 5.4 0.13 12.5 0.2 2.7 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit TPR_10 PF13374.6 ORY01019.1 - 0.56 10.1 2.3 41 4.2 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY01019.1 - 4.9 8.0 7.2 1.7e+02 3.2 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF866 PF05907.13 ORY01020.1 - 9.9e-60 200.9 2.0 1.1e-59 200.8 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ras PF00071.22 ORY01021.1 - 4.5e-56 188.9 0.1 5.3e-56 188.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY01021.1 - 7.6e-21 74.6 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY01021.1 - 1.9e-08 34.0 0.1 2.6e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY01021.1 - 5.7e-06 26.0 0.3 3.5e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY01021.1 - 5.6e-05 23.1 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY01021.1 - 0.0065 16.0 0.3 0.058 12.9 0.3 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY01021.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gly_kinase PF02595.15 ORY01021.1 - 0.046 12.7 0.0 7.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Glycerate kinase family IMP_cyclohyd PF07826.11 ORY01021.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein MMR_HSR1_Xtn PF16897.5 ORY01021.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_25 PF13481.6 ORY01021.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 ORY01021.1 - 0.14 12.2 0.1 0.41 10.7 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY01021.1 - 0.17 12.3 0.1 0.21 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain KilA-N PF04383.13 ORY01022.1 - 0.047 13.6 0.0 0.82 9.5 0.0 2.2 1 1 0 1 1 1 0 KilA-N domain Soc PF16855.5 ORY01022.1 - 0.12 12.8 0.1 11 6.6 0.0 2.2 2 0 0 2 2 2 0 Small outer capsid protein Sugar_tr PF00083.24 ORY01024.1 - 1.3e-78 264.9 27.7 5.5e-48 163.9 3.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY01024.1 - 5.1e-26 91.4 14.4 5.1e-26 91.4 14.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY01024.1 - 0.002 16.8 5.7 0.002 16.8 5.7 3.4 2 1 1 3 3 3 1 MFS/sugar transport protein GILT PF03227.16 ORY01025.1 - 0.014 15.7 2.3 0.022 15.0 2.3 1.4 1 1 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) CBM_19 PF03427.13 ORY01025.1 - 0.015 15.3 13.2 0.015 15.3 13.2 3.2 1 1 2 3 3 3 0 Carbohydrate binding domain (family 19) Biopterin_H PF00351.21 ORY01026.1 - 2.7e-170 565.7 0.0 3.4e-170 565.4 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 ORY01026.1 - 0.00013 21.7 0.4 0.00027 20.7 0.0 1.8 2 0 0 2 2 2 1 ACT domain YtxH PF12732.7 ORY01026.1 - 0.067 13.7 0.4 39 4.9 0.1 3.2 3 0 0 3 3 3 0 YtxH-like protein TipE PF16972.5 ORY01026.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Pkinase PF00069.25 ORY01027.1 - 5.8e-72 242.2 0.0 7.8e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01027.1 - 2.5e-37 128.5 0.0 4.1e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 ORY01027.1 - 2.9e-36 123.7 1.0 4.8e-36 123.0 0.2 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 ORY01027.1 - 2.7e-06 26.9 0.0 6.1e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY01027.1 - 9.9e-06 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY01027.1 - 0.0025 17.2 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY01027.1 - 0.0041 15.9 2.0 0.011 14.5 2.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY01027.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY01027.1 - 0.03 13.9 0.1 0.71 9.5 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY01027.1 - 0.045 13.4 0.8 0.12 12.0 0.0 1.8 1 1 0 2 2 2 0 RIO1 family PH_2 PF08458.10 ORY01027.1 - 0.099 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region AAA PF00004.29 ORY01028.1 - 2.5e-61 205.9 0.0 5.9e-37 127.0 0.0 3.3 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY01028.1 - 8e-31 105.6 0.3 5.4e-16 58.1 0.3 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY01028.1 - 6.7e-12 46.1 0.0 7.4e-05 23.2 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 ORY01028.1 - 3.6e-09 36.7 1.3 0.00024 21.1 0.0 4.5 3 2 1 4 4 4 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY01028.1 - 3.1e-07 30.3 0.1 0.017 14.8 0.0 3.1 3 1 1 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY01028.1 - 4.1e-06 27.1 0.0 0.015 15.6 0.0 3.2 3 1 0 3 3 3 2 AAA domain Rad17 PF03215.15 ORY01028.1 - 1.2e-05 25.4 0.0 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 ORY01028.1 - 2.6e-05 24.6 0.0 0.05 14.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 ORY01028.1 - 7.2e-05 23.0 0.0 0.12 12.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY01028.1 - 0.00014 21.7 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY01028.1 - 0.00014 21.4 0.0 0.086 12.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY01028.1 - 0.00015 21.2 0.0 0.13 11.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 ORY01028.1 - 0.00027 20.9 0.0 0.35 10.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 ORY01028.1 - 0.00039 21.0 0.0 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 ORY01028.1 - 0.00074 19.7 0.1 0.61 10.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 ORY01028.1 - 0.00092 19.2 0.0 0.32 11.0 0.0 2.6 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 ORY01028.1 - 0.0015 18.5 0.0 1.6 8.6 0.0 2.7 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 ORY01028.1 - 0.0018 18.9 0.0 0.19 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ORY01028.1 - 0.0024 17.2 0.0 1.5 8.1 0.0 2.7 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.6 ORY01028.1 - 0.0042 17.1 0.0 0.94 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 ORY01028.1 - 0.0047 16.8 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ORY01028.1 - 0.0076 16.2 0.2 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 ORY01028.1 - 0.0091 15.9 0.1 0.86 9.5 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.6 ORY01028.1 - 0.013 15.1 0.2 5.1 6.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORY01028.1 - 0.013 15.3 0.0 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY01028.1 - 0.015 15.0 0.9 0.63 9.7 0.0 2.9 4 0 0 4 4 2 0 AAA domain TniB PF05621.11 ORY01028.1 - 0.018 14.5 0.0 7.9 5.8 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 ORY01028.1 - 0.024 13.8 0.0 4.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 ORY01028.1 - 0.037 14.3 0.1 2.7 8.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.16 ORY01028.1 - 0.046 12.6 0.0 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase NB-ARC PF00931.22 ORY01028.1 - 0.055 12.6 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 ORY01028.1 - 0.068 12.9 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 ORY01028.1 - 0.083 12.6 0.0 2.2 7.9 0.0 3.0 3 1 0 3 3 3 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 ORY01028.1 - 0.092 12.6 0.0 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_28 PF13521.6 ORY01028.1 - 0.094 12.9 0.0 14 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4238 PF14022.6 ORY01028.1 - 0.17 11.4 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Glyco_hydro_17 PF00332.18 ORY01029.1 - 2.1e-14 53.8 3.4 2e-11 44.1 0.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2181 PF10223.9 ORY01029.1 - 0.036 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) PTPS PF01242.19 ORY01029.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase MACPF PF01823.19 ORY01029.1 - 0.064 13.3 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 MAC/Perforin domain Orn_Arg_deC_N PF02784.16 ORY01069.1 - 2e-66 223.9 0.0 2.5e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain CENP-B_N PF04218.13 ORY01069.1 - 0.15 11.7 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Trypsin PF00089.26 ORY01070.1 - 3.9e-13 49.7 0.6 7.3e-13 48.8 0.6 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY01070.1 - 0.0022 18.9 0.4 0.068 14.1 0.4 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 ORY01070.1 - 9.5 4.7 5.3 1.2 7.7 1.2 1.5 2 0 0 2 2 2 0 Peptidase S46 CHAP PF05257.16 ORY01071.1 - 7e-11 42.6 2.5 1.1e-10 41.9 2.5 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORY01072.1 - 6.9e-11 42.6 2.5 1.1e-10 41.9 2.5 1.3 1 0 0 1 1 1 1 CHAP domain CHAP PF05257.16 ORY01073.1 - 6.9e-11 42.6 2.5 1.1e-10 41.9 2.5 1.3 1 0 0 1 1 1 1 CHAP domain GMC_oxred_N PF00732.19 ORY01074.1 - 1.5e-30 106.6 0.1 2.8e-23 82.7 0.0 2.0 2 0 0 2 2 2 2 GMC oxidoreductase GIDA PF01134.22 ORY01074.1 - 0.0058 15.8 0.1 0.67 9.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORY01074.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MAP65_ASE1 PF03999.12 ORY01075.1 - 3.2e-25 88.9 30.4 9.1e-25 87.4 30.4 1.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) SlyX PF04102.12 ORY01075.1 - 0.053 14.2 4.1 0.42 11.3 0.0 3.6 4 0 0 4 4 4 0 SlyX CHASE3 PF05227.13 ORY01075.1 - 2.6 8.0 5.8 1.1 9.2 0.2 3.0 3 1 0 3 3 3 0 CHASE3 domain Meth_synt_2 PF01717.18 ORY01077.1 - 5.1e-158 525.5 0.0 7.2e-151 502.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY01077.1 - 1e-125 419.4 0.0 6.5e-118 393.8 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.18 ORY01078.1 - 9.9e-158 524.5 0.0 1.4e-150 501.1 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY01078.1 - 1e-125 419.4 0.0 6.6e-118 393.8 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain RNA_pol_Rpb2_6 PF00562.28 ORY01079.1 - 1.1e-113 380.3 0.0 2.6e-113 379.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY01079.1 - 8.7e-35 120.1 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ORY01079.1 - 3.6e-28 97.5 0.0 8.3e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 ORY01079.1 - 3.4e-26 91.0 0.0 7.6e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 ORY01079.1 - 1.4e-22 80.3 0.0 2.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY01079.1 - 6e-21 74.7 0.3 1.3e-20 73.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RRM_1 PF00076.22 ORY01080.1 - 1.3e-12 47.3 0.0 1.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY01080.1 - 0.0048 16.9 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY01080.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif MPC PF03650.13 ORY01081.1 - 6.8e-38 129.2 0.0 7.6e-38 129.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Complex1_LYR PF05347.15 ORY01082.1 - 4e-10 39.6 0.0 7.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY01082.1 - 0.0067 17.1 0.0 0.0086 16.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HC2 PF07382.11 ORY01083.1 - 1.5e-21 77.4 110.1 4.3e-12 46.5 64.3 3.2 2 1 0 2 2 2 2 Histone H1-like nucleoprotein HC2 Cyclin_N PF00134.23 ORY01084.1 - 2.5e-13 49.9 0.0 3.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY01084.1 - 1.4e-09 38.5 0.0 1.8e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin Tubulin PF00091.25 ORY01085.1 - 3.6e-72 242.7 0.2 1.1e-71 241.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY01085.1 - 4.1e-36 123.9 1.1 2.2e-35 121.5 1.1 2.0 1 1 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY01085.1 - 2.4e-06 27.9 0.0 5.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY01085.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORY01085.1 - 0.0042 16.3 0.2 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin like DUF3020 PF11223.8 ORY01086.1 - 1.5e-22 79.8 8.1 1.5e-22 79.8 8.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) Arrestin_C PF02752.22 ORY01087.1 - 1.5e-11 44.8 0.0 3.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY01087.1 - 7.1e-07 29.4 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY01087.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.4 1 1 0 1 1 1 1 Arrestin_N terminal like Hamartin PF04388.12 ORY01089.1 - 1.6e-17 63.5 32.5 5.3e-16 58.5 32.5 3.2 1 1 0 1 1 1 1 Hamartin protein Arrestin_C PF02752.22 ORY01090.1 - 5.1e-11 43.2 0.0 7.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY01090.1 - 0.0019 18.3 0.0 0.0067 16.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 ORY01090.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 SpoOM protein Vac_ImportDeg PF09783.9 ORY01091.1 - 4.3e-65 218.5 4.9 5.3e-65 218.2 4.9 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Formyl_trans_N PF00551.19 ORY01092.1 - 6.8e-52 175.8 0.0 7.7e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase bZIP_1 PF00170.21 ORY01093.1 - 9.4e-09 35.2 14.5 9.4e-09 35.2 14.5 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY01093.1 - 2.6e-08 33.8 14.2 2.6e-08 33.8 14.2 2.4 1 1 1 2 2 2 1 Basic region leucine zipper FlxA PF14282.6 ORY01093.1 - 0.0012 18.8 2.8 0.0023 17.9 2.8 1.4 1 0 0 1 1 1 1 FlxA-like protein bZIP_Maf PF03131.17 ORY01093.1 - 0.0015 19.0 11.2 0.0038 17.7 11.2 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 ORY01093.1 - 0.0073 16.7 7.8 0.017 15.6 7.8 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DUF3720 PF12517.8 ORY01093.1 - 0.0089 16.9 1.2 0.0089 16.9 1.2 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF3720) KASH_CCD PF14662.6 ORY01093.1 - 0.012 15.5 9.0 0.017 15.0 9.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 ORY01093.1 - 0.014 15.4 5.4 0.025 14.5 5.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit SHE3 PF17078.5 ORY01093.1 - 0.022 14.5 7.4 0.035 13.8 7.4 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FliD_C PF07195.12 ORY01093.1 - 0.026 13.9 3.1 0.036 13.5 3.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus UPF0242 PF06785.11 ORY01093.1 - 0.027 14.6 7.3 0.055 13.6 7.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ORY01093.1 - 0.029 14.9 10.0 0.046 14.2 10.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 ORY01093.1 - 0.031 13.6 8.1 0.057 12.8 8.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 ORY01093.1 - 0.059 13.6 3.6 0.096 12.9 3.1 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF3552 PF12072.8 ORY01093.1 - 0.068 12.6 9.5 0.1 12.0 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HALZ PF02183.18 ORY01093.1 - 0.091 13.0 5.9 0.18 12.1 5.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 ORY01093.1 - 0.1 13.1 2.4 0.11 13.0 1.0 1.8 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 ORY01093.1 - 0.12 11.3 8.4 0.16 10.8 8.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 ORY01093.1 - 0.16 12.0 3.1 0.35 10.9 3.1 1.5 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF5094 PF17015.5 ORY01093.1 - 0.17 12.0 2.6 0.27 11.3 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF1043 PF06295.12 ORY01093.1 - 0.18 11.8 2.7 0.33 11.0 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Nup88 PF10168.9 ORY01093.1 - 0.24 9.2 4.9 0.31 8.8 4.9 1.1 1 0 0 1 1 1 0 Nuclear pore component NAM-associated PF14303.6 ORY01093.1 - 0.4 11.4 9.8 0.75 10.5 9.8 1.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF724 PF05266.14 ORY01093.1 - 0.41 10.5 8.3 0.63 9.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fungal_TACC PF12709.7 ORY01093.1 - 0.68 10.4 4.9 1.1 9.7 4.3 1.7 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Rho_Binding PF08912.11 ORY01093.1 - 0.69 10.8 8.5 0.68 10.8 6.9 1.8 1 1 0 1 1 1 0 Rho Binding DASH_Hsk3 PF08227.11 ORY01093.1 - 1.7 9.0 5.5 1.2 9.6 3.2 1.8 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like DUF3450 PF11932.8 ORY01093.1 - 1.9 7.8 10.8 2.7 7.3 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CorA PF01544.18 ORY01093.1 - 2.2 7.5 5.6 3.7 6.8 5.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sas6_CC PF18594.1 ORY01093.1 - 2.6 7.9 5.0 6.6 6.6 0.4 2.5 1 1 1 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain DivIC PF04977.15 ORY01093.1 - 3 7.7 7.9 1 9.2 3.8 2.2 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 ORY01093.1 - 3.7 8.2 5.6 8.3 7.1 5.4 1.7 1 1 1 2 2 2 0 Initiation control protein YabA UPF0121 PF03661.13 ORY01094.1 - 2.2e-17 63.3 0.4 2.6e-17 63.0 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) E1-E2_ATPase PF00122.20 ORY01095.1 - 2.5e-45 154.2 0.4 2.5e-45 154.2 0.4 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY01095.1 - 5.3e-24 84.9 14.9 4.7e-19 68.8 2.5 3.2 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY01095.1 - 2.7e-20 72.2 0.0 9e-20 70.6 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY01095.1 - 6e-17 62.6 0.2 1.9e-14 54.5 0.2 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY01095.1 - 3.2e-12 46.0 0.0 7.1e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY01095.1 - 0.00021 21.1 2.2 0.02 14.7 0.7 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 ORY01095.1 - 2.9 6.6 6.5 4.9 5.8 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Copine PF07002.16 ORY01096.1 - 2.9e-62 210.0 0.0 3.9e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 ORY01096.1 - 9.6e-18 64.4 0.0 1e-10 41.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 ORY01096.1 - 0.003 17.7 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus TPR_2 PF07719.17 ORY01097.1 - 8.3e-16 56.8 2.6 0.0017 18.3 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY01097.1 - 1e-14 53.6 3.6 0.00023 20.8 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY01097.1 - 1.7e-11 43.4 4.6 0.012 15.7 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY01097.1 - 2.9e-11 42.9 0.0 0.0018 17.9 0.0 4.8 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 ORY01097.1 - 3.7e-10 39.7 3.1 0.78 10.7 0.0 7.0 4 2 3 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY01097.1 - 7e-09 35.8 1.3 0.0032 17.6 0.1 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY01097.1 - 9.2e-08 32.3 6.6 2.5 8.5 0.1 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY01097.1 - 8.7e-07 29.4 0.7 0.0024 18.3 0.2 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY01097.1 - 1.5e-06 28.2 1.1 0.58 10.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY01097.1 - 5.1e-06 27.0 0.6 0.1 13.3 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY01097.1 - 4e-05 23.0 3.7 0.0012 18.1 0.5 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY01097.1 - 0.00046 20.4 7.8 0.0034 17.7 0.3 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY01097.1 - 0.0036 17.2 2.9 30 4.9 0.2 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 ORY01097.1 - 0.048 13.9 1.7 52 4.4 0.1 5.0 4 1 1 5 5 5 0 PPR repeat TPR_10 PF13374.6 ORY01097.1 - 0.19 11.7 4.5 3.6 7.6 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY01097.1 - 0.52 11.1 6.5 44 5.0 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat FGase PF05013.12 ORY01098.1 - 6.4e-10 39.6 0.0 7.8e-06 26.2 0.0 3.0 1 1 1 2 2 2 2 N-formylglutamate amidohydrolase JAB PF01398.21 ORY01099.1 - 2.5e-12 46.8 0.0 2.1e-11 43.8 0.0 2.4 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TSNAXIP1_N PF15739.5 ORY01099.1 - 0.052 13.9 2.9 0.13 12.6 0.2 2.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus RabGAP-TBC PF00566.18 ORY01100.1 - 1.3e-37 129.5 0.3 1e-30 107.0 0.2 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain START PF01852.19 ORY01100.1 - 0.18 11.2 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 START domain Glyco_tranf_2_3 PF13641.6 ORY01102.1 - 3.6e-30 105.6 0.1 4.8e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY01102.1 - 5.8e-12 45.8 0.0 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY01102.1 - 1.3e-09 37.7 0.2 6.9e-09 35.4 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 ORY01102.1 - 5.6e-05 23.1 9.8 0.00015 21.8 9.8 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 ORY01102.1 - 0.0062 15.2 3.1 0.017 13.8 3.1 1.7 1 1 0 1 1 1 1 Chitin synthase Vac14_Fig4_bd PF11916.8 ORY01103.1 - 9.8e-82 272.9 6.5 2e-81 271.9 6.5 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 ORY01103.1 - 6.9e-43 145.2 0.5 8.8e-37 125.6 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ORY01103.1 - 2e-14 52.4 1.5 0.00039 20.4 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 ORY01103.1 - 1e-08 35.5 1.8 0.091 13.3 0.0 6.3 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 ORY01103.1 - 4.2e-07 30.3 4.6 1 9.8 0.0 5.4 5 1 2 7 7 7 3 HEAT repeats CLASP_N PF12348.8 ORY01103.1 - 3.5e-06 26.8 1.2 0.37 10.3 0.0 4.6 4 1 1 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 ORY01103.1 - 0.00016 21.8 6.8 1.2 9.2 0.1 4.9 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 ORY01103.1 - 0.01 16.1 0.0 5.8 7.3 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 ORY01103.1 - 0.014 14.7 0.1 0.044 13.0 0.1 2.0 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain RasGEF_N_2 PF14663.6 ORY01103.1 - 2.6 8.5 8.1 2.6 8.5 0.1 4.3 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain AA_permease_2 PF13520.6 ORY01104.1 - 7.8e-60 202.9 36.4 9.4e-60 202.6 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01104.1 - 8.1e-24 84.0 34.5 1.2e-23 83.5 34.5 1.2 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 ORY01133.1 - 2.4e-99 333.2 31.1 2.9e-99 333.0 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY01133.1 - 6.1e-21 74.7 31.6 1.2e-20 73.7 25.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 ORY01134.1 - 5.7e-33 114.0 0.0 8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY01134.1 - 2.4e-22 79.6 0.0 3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY01134.1 - 4.4e-11 43.0 0.0 5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY01134.1 - 0.00016 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ORY01134.1 - 0.0014 18.1 0.0 0.0044 16.4 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 ORY01134.1 - 0.091 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY01134.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 ORY01135.1 - 5.7e-33 114.3 25.8 8.3e-33 113.8 25.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SLC35F PF06027.12 ORY01135.1 - 1 8.8 8.8 0.55 9.7 3.7 2.4 1 1 1 2 2 2 0 Solute carrier family 35 Peptidase_S8 PF00082.22 ORY01136.1 - 8.8e-32 110.5 7.9 7.5e-31 107.5 7.9 2.2 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY01136.1 - 0.042 14.5 0.0 0.069 13.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 GATase_6 PF13522.6 ORY01137.1 - 1.7e-15 57.4 0.0 3.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY01137.1 - 4.1e-13 49.3 0.0 1e-12 48.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ORY01137.1 - 2.5e-07 30.3 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 ORY01137.1 - 2.7e-05 23.2 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II zf-Mss51 PF13824.6 ORY01138.1 - 9.6e-19 67.2 17.3 1.7e-18 66.4 17.3 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DTW PF03942.15 ORY01138.1 - 0.018 14.7 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 DTW domain DUF4840 PF16128.5 ORY01138.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) OrfB_Zn_ribbon PF07282.11 ORY01138.1 - 5.3 7.0 6.9 10 6.1 6.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Avl9 PF09794.9 ORY01139.1 - 2.7e-126 421.3 0.4 3.3e-126 421.0 0.4 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 ORY01139.1 - 1.3e-10 41.4 7.8 4.8e-05 23.1 1.0 3.6 3 1 1 4 4 4 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 ORY01139.1 - 3.8e-10 39.7 0.9 0.00096 19.1 0.0 2.9 3 0 0 3 3 3 2 Stabilization of polarity axis DENN PF02141.21 ORY01139.1 - 0.00048 20.1 1.6 0.049 13.6 0.4 3.0 2 1 1 3 3 3 1 DENN (AEX-3) domain Ribosomal_S19 PF00203.21 ORY01140.1 - 3.6e-36 122.9 1.0 4.7e-36 122.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Mito_carr PF00153.27 ORY01141.1 - 4.6e-29 100.2 1.3 3.6e-12 46.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY01141.1 - 0.009 15.2 0.1 0.042 13.0 0.0 2.1 3 0 0 3 3 3 1 Gammaproteobacterial serine protease GAD-like PF08887.11 ORY01141.1 - 0.11 12.3 0.1 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 GAD-like domain RRM_2 PF04059.12 ORY01142.1 - 1.3e-44 150.4 0.5 2.4e-44 149.4 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 BRAP2 PF07576.12 ORY01142.1 - 0.082 13.1 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_1 PF00076.22 ORY01142.1 - 0.086 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPRY PF00622.28 ORY01143.1 - 9.1e-22 77.4 0.4 1.6e-17 63.7 0.1 2.6 2 0 0 2 2 2 2 SPRY domain Arm PF00514.23 ORY01143.1 - 2.8e-15 55.7 0.9 0.0022 18.0 0.0 7.5 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 ORY01143.1 - 4.6e-07 29.4 14.5 1.8e-05 24.2 3.0 3.4 1 1 1 3 3 3 2 V-ATPase subunit H HEAT_2 PF13646.6 ORY01143.1 - 2.2e-05 24.8 0.0 2.4 8.6 0.1 4.3 3 1 0 4 4 4 2 HEAT repeats DUF3361 PF11841.8 ORY01143.1 - 0.00022 21.2 14.3 0.32 10.9 0.3 3.9 2 1 0 3 3 3 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 ORY01143.1 - 0.0011 19.0 6.6 0.38 10.9 0.0 5.0 4 1 1 5 5 5 1 V-ATPase subunit H Cnd1 PF12717.7 ORY01143.1 - 0.0032 17.5 5.6 0.052 13.6 0.1 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORY01143.1 - 0.0063 16.7 6.3 4.6 7.5 0.2 3.9 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Gon7 PF08738.10 ORY01143.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Gon7 family Vac14_Fab1_bd PF12755.7 ORY01143.1 - 0.02 15.5 1.7 4.7 7.9 0.0 3.9 3 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region DUF1765 PF08578.10 ORY01143.1 - 0.27 11.7 3.9 0.27 11.7 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) CTNNBL PF08216.11 ORY01143.1 - 0.46 10.7 3.6 4.3 7.6 0.4 3.8 3 1 1 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear Transket_pyr PF02779.24 ORY01144.1 - 2.4e-43 147.9 0.0 3.6e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY01144.1 - 6.5e-43 145.5 0.0 1.2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ORY01144.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II NUC153 PF08159.12 ORY01145.1 - 1.1e-17 63.5 15.0 4e-16 58.5 0.9 4.5 4 0 0 4 4 4 3 NUC153 domain eRF1_1 PF03463.15 ORY01146.1 - 4.8e-54 181.8 0.2 8e-54 181.1 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 ORY01146.1 - 2e-32 112.3 0.3 2.9e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORY01146.1 - 7.3e-26 90.9 0.0 2.2e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 DUF1664 PF07889.12 ORY01147.1 - 0.00029 20.8 10.3 0.045 13.8 2.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) ADIP PF11559.8 ORY01147.1 - 0.00069 19.7 14.5 0.0018 18.3 2.0 2.5 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 ORY01147.1 - 0.00088 18.5 4.7 0.002 17.3 4.7 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Herpes_UL6 PF01763.16 ORY01147.1 - 0.0014 17.3 2.7 0.0014 17.3 2.7 2.0 1 1 1 2 2 2 1 Herpesvirus UL6 like NPV_P10 PF05531.12 ORY01147.1 - 0.013 16.0 1.9 0.11 13.0 0.1 2.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LIME1 PF15332.6 ORY01147.1 - 0.048 13.3 0.5 0.048 13.3 0.5 2.1 2 1 0 2 2 2 0 Lck-interacting transmembrane adapter 1 Cas6 PF09559.10 ORY01147.1 - 0.16 11.9 2.5 0.3 11.0 2.5 1.3 1 0 0 1 1 1 0 Cas6 Crispr Phage_GP20 PF06810.11 ORY01147.1 - 0.2 11.5 7.5 0.22 11.3 1.7 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fmp27_WPPW PF10359.9 ORY01147.1 - 0.27 10.0 14.0 0.056 12.3 1.3 2.2 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Mod_r PF07200.13 ORY01147.1 - 0.31 11.2 17.8 0.033 14.3 2.1 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ApoC-I PF04691.12 ORY01147.1 - 0.39 10.7 3.3 14 5.7 0.0 3.1 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) APG6_N PF17675.1 ORY01147.1 - 0.61 10.6 23.3 0.11 13.0 6.4 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region FemAB PF02388.16 ORY01147.1 - 0.81 8.5 6.0 5.1 5.8 0.1 2.3 2 0 0 2 2 2 0 FemAB family HemX PF04375.14 ORY01147.1 - 1 8.6 11.6 1.7 7.8 3.8 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF16 PF01519.16 ORY01147.1 - 1.2 9.7 9.9 6.6 7.3 1.9 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 ORY01147.1 - 1.5 9.0 8.0 6.1 7.0 2.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF812 PF05667.11 ORY01147.1 - 2.1 7.1 14.8 18 4.1 14.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Spc24 PF08286.11 ORY01147.1 - 2.1 8.6 13.7 1.9 8.8 4.0 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 ECH_2 PF16113.5 ORY01147.1 - 2.2 7.7 4.4 1.5 8.2 1.1 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase TMPIT PF07851.13 ORY01147.1 - 2.6 7.2 7.9 0.4 9.9 1.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 ORY01147.1 - 2.6 8.4 5.6 1.3 9.4 0.8 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 ORY01147.1 - 3 7.1 18.8 0.15 11.4 1.6 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 ORY01147.1 - 3 7.9 21.9 0.14 12.2 5.5 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Helo_like_N PF17111.5 ORY01147.1 - 3.2 7.1 11.4 0.28 10.5 2.8 2.3 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins LMBR1 PF04791.16 ORY01147.1 - 3.4 6.5 7.2 13 4.6 7.1 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein FUSC PF04632.12 ORY01147.1 - 4.2 5.8 7.1 2.3 6.6 0.7 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Phage_Mu_Gam PF07352.12 ORY01147.1 - 4.5 7.2 9.6 0.78 9.6 2.1 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein HMMR_N PF15905.5 ORY01147.1 - 4.6 6.6 18.4 0.018 14.5 2.4 2.4 3 0 0 3 3 2 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 ORY01147.1 - 4.8 7.2 20.8 0.97 9.5 3.5 2.6 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 ORY01147.1 - 5 7.6 10.5 10 6.6 0.3 3.5 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4795 PF16043.5 ORY01147.1 - 5 6.7 16.0 0.39 10.3 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) CLZ PF16526.5 ORY01147.1 - 5.4 7.4 14.3 6.2 7.3 1.8 3.2 2 2 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med9 PF07544.13 ORY01147.1 - 8.7 6.5 8.6 16 5.6 0.9 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.9 ORY01147.1 - 9.1 7.0 12.4 6 7.6 0.9 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) PS_Dcarbxylase PF02666.15 ORY01148.1 - 4.1e-60 202.7 0.0 6.1e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ORY01148.1 - 8.1e-37 125.6 0.0 1.2e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF1033 PF06279.11 ORY01148.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Wbp11 PF09429.10 ORY01149.1 - 4.7e-08 33.3 12.1 4.7e-08 33.3 12.1 1.7 2 0 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.7 ORY01149.1 - 0.89 10.4 46.4 25 5.7 44.3 4.0 2 1 0 2 2 2 0 mRNA biogenesis factor GSHPx PF00255.19 ORY01150.1 - 2.4e-44 149.3 0.2 3.1e-44 149.0 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY01150.1 - 7.7e-09 35.5 0.1 1.3e-08 34.8 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY01150.1 - 4.1e-05 23.3 0.3 0.00041 20.1 0.3 2.0 1 1 0 1 1 1 1 Redoxin Fer2 PF00111.27 ORY01151.1 - 1.3e-11 44.3 0.2 1.6e-11 43.9 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cyt-b5 PF00173.28 ORY01152.1 - 2.5e-14 53.1 0.0 3.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIF PF03031.18 ORY01153.1 - 4.4e-48 163.0 0.1 6e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase 6PF2K PF01591.18 ORY01154.1 - 1.7e-84 282.6 0.1 2.1e-84 282.3 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY01154.1 - 5.9e-35 120.7 0.0 8.3e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY01154.1 - 3.3e-05 24.1 0.0 6.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DCP2 PF05026.13 ORY01155.1 - 4.5e-25 87.8 1.3 7.9e-25 87.0 1.3 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 ORY01155.1 - 6.8e-15 55.3 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PH PF00169.29 ORY01156.1 - 6.3e-10 39.5 0.1 1.5e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY01156.1 - 0.1 13.0 0.3 0.92 10.0 0.3 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Glyoxalase PF00903.25 ORY01157.1 - 1.7e-23 83.2 1.4 3.3e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY01157.1 - 1.5e-11 44.5 0.2 7.7e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 ORY01157.1 - 1.9e-07 31.3 0.2 5.7e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 ORY01157.1 - 3e-06 27.5 0.2 0.015 15.4 0.1 3.7 2 1 1 3 3 3 2 Glyoxalase-like domain MutS_IV PF05190.18 ORY01157.1 - 0.0085 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV Glyoxalase_6 PF18029.1 ORY01157.1 - 0.088 13.6 0.0 3.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 ORY01158.1 - 1.7e-23 83.2 1.4 3.3e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY01158.1 - 1.5e-11 44.5 0.2 7.7e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 ORY01158.1 - 1.9e-07 31.3 0.2 5.7e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 ORY01158.1 - 3e-06 27.5 0.2 0.015 15.4 0.1 3.7 2 1 1 3 3 3 2 Glyoxalase-like domain MutS_IV PF05190.18 ORY01158.1 - 0.0085 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV Glyoxalase_6 PF18029.1 ORY01158.1 - 0.088 13.6 0.0 3.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 ORY01159.1 - 5.4e-23 81.6 2.0 3.4e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY01159.1 - 8.3e-11 42.1 0.3 0.0004 20.6 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ORY01159.1 - 3.1e-06 27.4 0.5 0.0079 16.3 0.4 3.5 2 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 ORY01159.1 - 3.6e-06 27.2 0.8 1.5e-05 25.2 0.5 2.1 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal MutS_IV PF05190.18 ORY01159.1 - 0.0089 16.4 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV Glyoxalase_6 PF18029.1 ORY01159.1 - 0.11 13.3 0.0 3.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 ORY01160.1 - 1.7e-23 83.2 1.4 3.3e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY01160.1 - 1.5e-11 44.5 0.2 7.7e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 ORY01160.1 - 1.9e-07 31.3 0.2 5.7e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 ORY01160.1 - 3e-06 27.5 0.2 0.015 15.4 0.1 3.7 2 1 1 3 3 3 2 Glyoxalase-like domain MutS_IV PF05190.18 ORY01160.1 - 0.0085 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV Glyoxalase_6 PF18029.1 ORY01160.1 - 0.088 13.6 0.0 3.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain PDT PF00800.18 ORY01161.1 - 1.9e-40 138.6 0.0 2.5e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ORY01161.1 - 2.3e-06 27.3 0.0 5.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain Sugar-bind PF04198.13 ORY01161.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain IFT20 PF14931.6 ORY01161.1 - 0.096 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 ubiquitin PF00240.23 ORY01162.1 - 6e-16 58.0 0.0 1.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ORY01162.1 - 2.5e-07 30.4 0.2 9.8e-07 28.6 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 ORY01162.1 - 2.6e-07 30.3 0.0 8.9e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY01162.1 - 1.1e-05 26.0 0.1 6.6e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain STI1 PF17830.1 ORY01162.1 - 0.00014 21.7 2.6 0.00014 21.7 2.6 3.1 2 1 1 3 3 3 2 STI1 domain Rad60-SLD_2 PF13881.6 ORY01162.1 - 0.00017 21.6 0.0 0.00051 20.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY01162.1 - 0.0097 16.3 0.1 0.026 15.0 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain HOIP-UBA PF16678.5 ORY01162.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair Coatomer_E PF04733.14 ORY01163.1 - 4.7e-93 311.8 0.4 5.3e-93 311.6 0.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 ORY01163.1 - 1.7e-09 38.0 5.3 0.00026 21.4 0.4 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY01163.1 - 2.6e-07 30.8 1.0 0.00067 19.8 0.1 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY01163.1 - 1.6e-06 28.3 2.2 0.0093 16.2 0.3 3.9 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY01163.1 - 0.0002 21.2 2.8 0.14 12.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY01163.1 - 0.00044 20.0 0.0 2.4 8.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORY01163.1 - 0.00064 19.7 0.1 0.54 10.3 0.0 2.7 2 1 0 2 2 2 2 Putative TPR-like repeat RPN7 PF10602.9 ORY01163.1 - 0.00095 18.9 0.0 0.0021 17.8 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_16 PF13432.6 ORY01163.1 - 0.0037 17.9 0.0 6 7.6 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF5588 PF17826.1 ORY01163.1 - 0.013 14.4 0.1 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5588) TPR_7 PF13176.6 ORY01163.1 - 0.017 15.1 0.0 9.5 6.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY01163.1 - 0.035 14.7 0.0 29 5.7 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat PUL PF08324.11 ORY01163.1 - 0.042 13.1 0.3 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 PUL domain TPR_10 PF13374.6 ORY01163.1 - 0.055 13.3 1.5 1.2 9.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY01163.1 - 0.36 11.6 2.9 2.4e+02 2.7 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 ORY01164.1 - 5.9e-71 238.9 0.0 7.3e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY01164.1 - 4.3e-09 36.5 0.2 9e-09 35.4 0.2 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TMEM208_SND2 PF05620.11 ORY01165.1 - 1.6e-54 184.1 0.1 1.9e-54 183.9 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Spb1_C PF07780.12 ORY01166.1 - 1.6e-79 266.5 38.2 1.6e-79 266.5 38.2 4.2 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 ORY01166.1 - 1.6e-56 191.2 0.5 9.9e-56 188.6 0.0 2.5 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.8 ORY01166.1 - 3.8e-47 160.2 17.1 3.8e-47 160.2 17.1 5.3 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) DUF148 PF02520.17 ORY01166.1 - 0.0025 17.9 5.6 0.0025 17.9 5.6 3.1 4 0 0 4 4 4 1 Domain of unknown function DUF148 DUF3564 PF12087.8 ORY01166.1 - 0.065 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) RcpC PF16976.5 ORY01166.1 - 1.2 9.2 4.2 0.42 10.7 0.5 2.3 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB Glyco_hydro_72 PF03198.14 ORY01167.1 - 8.5e-126 419.5 2.8 1.1e-125 419.1 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ORY01167.1 - 1.7e-22 79.9 4.2 3.7e-22 78.8 4.2 1.6 1 0 0 1 1 1 1 X8 domain GREB1 PF15782.5 ORY01167.1 - 1.6 5.8 18.5 2.2 5.3 18.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CC190 PF15768.5 ORY01167.1 - 1.7 8.7 16.4 2.8 7.9 16.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Lin-8 PF03353.15 ORY01167.1 - 3.2 7.2 10.6 4.8 6.7 10.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 ORY01167.1 - 6.6 5.2 17.6 10 4.6 17.6 1.2 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 ORY01167.1 - 9.2 6.1 9.2 15 5.5 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Sulfatase PF00884.23 ORY01168.1 - 3.4e-26 92.3 3.5 6.1e-26 91.5 3.5 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 ORY01168.1 - 0.088 11.4 0.1 0.17 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) p450 PF00067.22 ORY01209.1 - 8.5e-49 166.5 0.2 1.1e-48 166.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 ORY01210.1 - 3.4e-35 121.0 0.0 5.9e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY01210.1 - 4e-33 114.2 0.0 5.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 ORY01210.1 - 0.0047 17.1 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_10 PF13460.6 ORY01210.1 - 0.0099 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 ORY01210.1 - 0.012 15.9 0.1 0.097 12.9 0.1 2.2 1 1 0 1 1 1 0 TrkA-N domain DAO PF01266.24 ORY01210.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY01210.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY01210.1 - 0.025 15.2 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ORY01210.1 - 0.042 14.4 0.0 0.24 12.0 0.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 ORY01210.1 - 0.09 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 ThiF family Pkinase PF00069.25 ORY01211.1 - 9.4e-64 215.3 0.0 3.9e-63 213.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01211.1 - 5.9e-28 97.9 0.0 1.7e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY01211.1 - 0.00011 21.2 0.1 0.00016 20.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY01211.1 - 0.002 17.5 0.0 0.0065 15.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY01211.1 - 0.0036 17.3 6.5 0.045 13.7 0.5 2.8 3 1 0 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY01211.1 - 0.0061 15.9 1.3 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 ORY01211.1 - 0.35 11.6 1.1 1.1 10.0 1.1 1.9 1 1 0 1 1 1 0 Protein kinase C terminal domain Vma12 PF11712.8 ORY01212.1 - 6.1e-29 100.9 0.2 6.1e-29 100.9 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DinI PF06183.13 ORY01212.1 - 0.0065 16.8 0.2 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 DinI-like family YabA PF06156.13 ORY01212.1 - 1.7 9.3 6.2 0.54 10.9 2.8 2.1 2 1 0 2 2 2 0 Initiation control protein YabA FBPase PF00316.20 ORY01213.1 - 4.8e-75 251.2 0.6 6.7e-75 250.7 0.6 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 ORY01213.1 - 0.00027 20.5 0.0 0.00075 19.1 0.0 1.7 2 0 0 2 2 2 1 Inositol monophosphatase family zf_CCCH_4 PF18345.1 ORY01213.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger domain CAP PF00188.26 ORY01214.1 - 1.8e-13 51.4 0.6 2.4e-13 51.0 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Asn_synthase PF00733.21 ORY01214.1 - 0.0095 15.6 0.3 0.011 15.4 0.3 1.0 1 0 0 1 1 1 1 Asparagine synthase SAA PF00277.18 ORY01214.1 - 0.07 13.6 1.7 0.12 12.9 1.5 1.5 1 1 1 2 2 2 0 Serum amyloid A protein CAP PF00188.26 ORY01215.1 - 1.8e-13 51.4 0.6 2.4e-13 51.0 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Asn_synthase PF00733.21 ORY01215.1 - 0.0095 15.6 0.3 0.011 15.4 0.3 1.0 1 0 0 1 1 1 1 Asparagine synthase SAA PF00277.18 ORY01215.1 - 0.07 13.6 1.7 0.12 12.9 1.5 1.5 1 1 1 2 2 2 0 Serum amyloid A protein Cytidylate_kin PF02224.18 ORY01216.1 - 8.5e-06 25.6 2.7 1.5e-05 24.8 2.7 1.4 1 1 0 1 1 1 1 Cytidylate kinase PhyH PF05721.13 ORY01216.1 - 0.12 12.6 0.1 0.37 11.0 0.0 1.7 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) PX PF00787.24 ORY01217.1 - 1.8e-14 53.7 0.0 8e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 PX domain XhlA PF10779.9 ORY01217.1 - 0.13 12.4 2.7 0.3 11.3 0.3 2.7 3 0 0 3 3 3 0 Haemolysin XhlA KxDL PF10241.9 ORY01217.1 - 1.7 9.0 10.0 0.7 10.2 3.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein BLI1 PF17324.2 ORY01217.1 - 1.9 9.2 5.6 1.4 9.6 0.6 2.6 2 1 1 3 3 3 0 BLOC-1 interactor 1 CLZ PF16526.5 ORY01217.1 - 2.1 8.8 10.4 7.3 7.0 0.2 3.8 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 ORY01217.1 - 5.4 6.7 9.0 5.7 6.6 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) AP1AR PF15745.5 ORY01218.1 - 0.00036 20.3 12.9 0.00036 20.3 12.9 1.7 1 1 1 2 2 2 1 AP-1 complex-associated regulatory protein Mis12 PF05859.12 ORY01219.1 - 2.5e-39 134.4 2.0 2.5e-39 134.4 2.0 1.6 2 1 0 2 2 2 1 Mis12 protein Lzipper-MIP1 PF14389.6 ORY01219.1 - 0.0078 16.5 3.4 0.0078 16.5 3.4 1.9 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 RRT14 PF17075.5 ORY01219.1 - 0.021 15.0 3.5 0.021 15.0 3.5 2.2 1 1 0 2 2 2 0 Regular of rDNA transcription protein 14 DUF4600 PF15372.6 ORY01219.1 - 0.035 14.6 5.6 0.083 13.3 5.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) HrpB7 PF09486.10 ORY01219.1 - 0.082 13.3 3.8 0.15 12.4 3.8 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 ORY01219.1 - 0.21 10.6 3.3 0.3 10.1 3.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L29 PF00831.23 ORY01219.1 - 0.43 10.6 5.6 11 6.1 1.8 2.7 2 0 0 2 2 2 0 Ribosomal L29 protein SlyX PF04102.12 ORY01219.1 - 0.85 10.3 5.3 38 5.0 0.0 3.5 2 1 1 3 3 3 0 SlyX betaPIX_CC PF16523.5 ORY01219.1 - 1.2 9.0 7.7 3.3 7.6 0.1 3.1 2 1 1 3 3 3 0 betaPIX coiled coil Ribosomal_L44 PF00935.19 ORY01220.1 - 3.9e-37 126.6 11.0 5.7e-37 126.0 11.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 PseudoU_synth_1 PF01416.20 ORY01221.1 - 7.8e-14 52.1 0.0 2e-10 41.1 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase RRM_1 PF00076.22 ORY01222.1 - 1.2e-12 47.5 0.1 1.6e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF424 PF04242.13 ORY01222.1 - 0.075 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF424) PTR2 PF00854.21 ORY01223.1 - 6.7e-93 311.6 4.5 9.4e-93 311.2 4.5 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY01223.1 - 4.6e-15 55.4 10.8 4.6e-15 55.4 10.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01223.1 - 0.00087 18.3 17.8 0.011 14.7 2.7 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter Amidohydro_1 PF01979.20 ORY01224.1 - 2.2e-56 191.6 0.0 2.9e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY01224.1 - 1.9e-10 40.9 0.2 3.9e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Arm PF00514.23 ORY01225.1 - 0.00011 22.1 1.9 0.00042 20.3 0.1 3.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY01225.1 - 0.053 14.0 6.4 0.1 13.1 0.6 3.9 4 0 0 4 4 4 0 HEAT-like repeat Ribonuclease_3 PF00636.26 ORY01225.1 - 0.11 13.1 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain Peroxin-13_N PF04088.13 ORY01226.1 - 4.7e-39 134.0 6.1 9.9e-39 132.9 6.1 1.5 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 ORY01226.1 - 2e-13 49.8 0.0 4.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY01226.1 - 4.3e-13 48.6 0.0 9.7e-13 47.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY01226.1 - 1.2e-12 47.5 0.0 2.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Pex16 PF08610.10 ORY01227.1 - 6.1e-113 377.2 0.0 6.9e-113 377.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PTR2 PF00854.21 ORY01228.1 - 3.7e-92 309.2 5.1 6.3e-92 308.4 5.1 1.4 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY01228.1 - 1.7e-13 50.3 13.1 5.1e-13 48.7 7.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01228.1 - 0.0014 17.6 21.4 0.0098 14.8 7.2 3.2 2 2 0 2 2 2 1 Sugar (and other) transporter Frag1 PF10277.9 ORY01229.1 - 4.6e-33 114.6 15.1 4.6e-33 114.6 15.1 2.8 2 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family PP2C PF00481.21 ORY01230.1 - 2.2e-44 152.0 0.0 3.1e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY01230.1 - 0.014 15.1 0.0 0.042 13.5 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C SpoIIE PF07228.12 ORY01230.1 - 0.048 13.6 0.0 1.2 9.0 0.0 2.6 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PCI PF01399.27 ORY01231.1 - 7.4e-22 77.8 0.4 5.7e-21 75.0 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 ORY01231.1 - 7e-19 67.6 6.0 2e-18 66.2 6.0 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain ERp29 PF07749.12 ORY01231.1 - 0.078 13.9 2.8 0.87 10.5 0.7 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain TPR_20 PF14561.6 ORY01231.1 - 0.094 13.1 0.1 0.32 11.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.19 ORY01232.1 - 4.7e-78 262.5 0.0 6.3e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY01232.1 - 7.8e-05 21.8 0.0 0.0011 18.0 0.0 2.2 3 0 0 3 3 3 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORY01233.1 - 3e-37 128.6 0.0 3.4e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY01233.1 - 5.1e-05 22.2 0.0 9.4e-05 21.4 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Mac PF12464.8 ORY01233.1 - 0.15 12.3 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Maltose acetyltransferase UDPGT PF00201.18 ORY01234.1 - 1.1e-16 60.7 0.0 1.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY01234.1 - 0.00064 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY01235.1 - 2.5e-19 69.5 0.0 4.8e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY01235.1 - 0.004 17.2 0.1 0.0064 16.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY01236.1 - 1.4e-16 60.4 0.0 1.9e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY01236.1 - 0.00039 20.4 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TolB_like PF15869.5 ORY01236.1 - 0.097 11.9 0.0 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 TolB-like 6-blade propeller-like UDPGT PF00201.18 ORY01237.1 - 2.6e-15 56.2 0.1 5.4e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF3439 PF11921.8 ORY01237.1 - 0.11 12.4 1.1 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UDPGT PF00201.18 ORY01238.1 - 5e-06 25.6 0.0 9.5e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 ORY01239.1 - 5.2e-12 45.3 0.0 9.3e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY01239.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY01240.1 - 4.5e-16 58.7 0.1 7.7e-16 58.0 0.1 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY01240.1 - 8.8e-05 22.5 0.3 0.00014 21.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain DEAD PF00270.29 ORY01241.1 - 7.1e-49 165.9 0.0 1.8e-48 164.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY01241.1 - 1.2e-31 109.3 0.0 3.1e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY01241.1 - 0.016 15.2 0.0 0.057 13.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY01241.1 - 0.083 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NAD_binding_10 PF13460.6 ORY01242.1 - 1.4e-07 31.6 0.0 3.6e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY01242.1 - 1.2e-06 28.2 0.0 4.3e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY01242.1 - 0.00021 20.6 1.1 0.004 16.4 1.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 ORY01242.1 - 0.0011 18.1 0.0 0.0081 15.2 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ORY01242.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ORY01242.1 - 0.0015 17.7 0.0 0.037 13.1 0.0 2.5 2 1 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 ORY01242.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 ORY01242.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family Cse1 PF08506.10 ORY01243.1 - 1.2e-158 527.8 5.6 1.2e-158 527.8 5.6 1.7 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 ORY01243.1 - 3.1e-156 520.3 8.6 3.9e-156 520.0 5.5 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 ORY01243.1 - 3.1e-14 52.6 0.7 2.9e-13 49.5 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain UME PF08064.13 ORY01243.1 - 0.0003 20.6 0.1 1.1 9.2 0.0 3.6 3 1 0 3 3 3 2 UME (NUC010) domain Xpo1 PF08389.12 ORY01243.1 - 0.0098 16.0 0.7 0.0098 16.0 0.7 5.4 5 2 0 5 5 5 1 Exportin 1-like protein MFS_1 PF07690.16 ORY01244.1 - 7e-18 64.7 26.2 1.1e-17 64.0 26.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY01244.1 - 6.2e-11 42.2 6.2 6.2e-11 42.2 6.2 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY01245.1 - 7e-18 64.7 26.2 1.1e-17 64.0 26.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY01245.1 - 6.2e-11 42.2 6.2 6.2e-11 42.2 6.2 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY01246.1 - 3.1e-18 65.8 25.5 5.4e-18 65.1 25.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY01246.1 - 6.2e-11 42.2 6.2 6.2e-11 42.2 6.2 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Nepo_coat PF03391.15 ORY01246.1 - 0.081 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, central domain 5_nucleotid PF05761.14 ORY01247.1 - 6.8e-132 440.6 5.1 8.1e-132 440.4 5.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 ORY01247.1 - 0.0066 16.5 1.2 0.17 11.9 0.0 3.1 4 0 0 4 4 4 1 Haloacid dehalogenase-like hydrolase RNA_pol_Rpb2_4 PF04566.13 ORY01247.1 - 0.077 13.3 0.9 40 4.6 0.0 3.7 4 0 0 4 4 4 0 RNA polymerase Rpb2, domain 4 Hydrolase PF00702.26 ORY01247.1 - 0.23 11.7 0.0 0.53 10.5 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase OGG_N PF07934.12 ORY01248.1 - 1.9e-24 86.1 0.8 2.9e-16 59.6 0.1 2.5 1 1 1 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 ORY01248.1 - 5.2e-16 59.0 0.0 8.7e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY01248.1 - 0.0027 17.5 0.0 0.0078 16.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif T6SS_TssG PF06996.11 ORY01248.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion, TssG SecY PF00344.20 ORY01249.1 - 2.7e-70 237.0 11.3 4.2e-70 236.4 11.3 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY01249.1 - 5.9e-19 67.6 0.2 2e-18 65.9 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p RseC_MucC PF04246.12 ORY01249.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ATP-synt_ab PF00006.25 ORY01250.1 - 7.8e-62 208.7 0.0 1.2e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY01250.1 - 5e-22 78.2 0.8 1.1e-21 77.1 0.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ORY01250.1 - 0.015 14.6 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ORY01250.1 - 0.026 13.7 0.8 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 ORY01250.1 - 0.059 13.7 0.8 0.45 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY01250.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORY01250.1 - 0.075 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORY01250.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Med2 PF11214.8 ORY01250.1 - 0.14 12.3 0.0 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 RNA_helicase PF00910.22 ORY01250.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase P21-Arc PF04062.14 ORY01251.1 - 5.8e-81 270.7 0.0 6.4e-81 270.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Chitin_synth_2 PF03142.15 ORY01252.1 - 7.3e-239 793.7 1.3 1.2e-238 793.1 1.3 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY01252.1 - 3.5e-130 435.3 3.6 4.5e-130 435.0 3.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY01252.1 - 7.3e-15 54.6 0.0 2.6e-14 52.9 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORY01252.1 - 1.6e-10 41.2 3.6 1.6e-10 41.2 3.6 3.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY01252.1 - 1e-09 38.7 0.0 7.6e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORY01252.1 - 1.9e-09 37.6 1.1 8.3e-05 22.7 0.1 3.7 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY01252.1 - 0.012 15.4 0.0 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 AAA_5 PF07728.14 ORY01252.1 - 0.1 12.6 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_transf_21 PF13506.6 ORY01252.1 - 0.11 12.0 0.2 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Peptidase_S10 PF00450.22 ORY01253.1 - 4.9e-122 408.3 1.0 6.1e-122 408.0 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 ORY01254.1 - 2.1e-102 343.3 25.7 2.5e-102 343.1 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY01254.1 - 1.3e-26 93.4 26.8 1.3e-26 93.4 26.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4229 PF14012.6 ORY01254.1 - 8.3 6.6 9.9 0.41 10.8 2.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) FAP PF07174.11 ORY01255.1 - 7.2 6.0 21.6 8.6 5.7 21.6 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CDC27 PF09507.10 ORY01255.1 - 8.3 5.7 12.8 9.7 5.5 12.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CTD_bind PF04818.13 ORY01297.1 - 6.8e-09 36.4 0.0 2.3e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 ORY01297.1 - 5.1e-06 26.9 2.8 5.1e-06 26.9 2.8 2.6 3 0 0 3 3 3 1 Subunit of cleavage factor IA Pcf11 CTK3 PF12243.8 ORY01297.1 - 0.0034 17.4 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 zf_UBZ PF18439.1 ORY01297.1 - 3.1 7.5 9.3 7.3 6.3 5.0 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Apolipoprotein PF01442.18 ORY01298.1 - 0.012 15.4 2.4 0.018 14.9 2.4 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BetR PF08667.10 ORY01298.1 - 0.18 11.8 1.6 0.28 11.2 1.6 1.2 1 0 0 1 1 1 0 BetR domain DUF1764 PF08576.10 ORY01298.1 - 0.26 12.2 1.6 0.43 11.5 1.6 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GARP PF16731.5 ORY01298.1 - 4.3 7.0 14.3 6.8 6.3 14.3 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma YtxH PF12732.7 ORY01298.1 - 7.1 7.2 11.0 2e+02 2.6 11.0 3.1 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.11 ORY01299.1 - 0.025 14.7 0.7 0.17 12.0 0.1 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PDR_assoc PF08370.11 ORY01299.1 - 0.08 12.7 0.7 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF5511 PF17630.2 ORY01299.1 - 0.19 11.9 0.2 0.34 11.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5511) YtxH PF12732.7 ORY01299.1 - 0.71 10.4 7.6 68 4.1 7.6 2.9 1 1 0 1 1 1 0 YtxH-like protein Peptidase_M20 PF01546.28 ORY01300.1 - 1.8e-28 99.7 0.0 2.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 ORY01300.1 - 2.3e-21 75.7 17.0 1.6e-06 28.7 0.5 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat M20_dimer PF07687.14 ORY01300.1 - 1.8e-10 40.7 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40_like PF17005.5 ORY01300.1 - 0.00036 20.0 0.2 0.058 12.7 0.1 2.4 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 ORY01300.1 - 0.00096 19.4 0.1 14 6.0 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY01300.1 - 0.0054 15.4 0.2 0.38 9.4 0.0 3.2 2 2 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 ORY01300.1 - 0.03 14.8 4.4 41 4.8 0.0 5.4 5 1 1 6 6 6 0 PQQ-like domain E1-E2_ATPase PF00122.20 ORY01301.1 - 2.6e-32 111.8 3.0 2.9e-32 111.7 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 ORY01301.1 - 6.6e-26 90.9 4.9 4.7e-25 88.1 4.9 2.5 1 1 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 ORY01301.1 - 4.4e-17 63.1 0.0 2.9e-09 37.5 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORY01301.1 - 3.1e-09 36.8 8.0 3.1e-09 36.8 8.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY01301.1 - 2.5e-05 24.3 0.2 8.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY01301.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY01301.1 - 0.059 13.1 0.1 0.63 9.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FAD_binding_1 PF00667.20 ORY01302.1 - 3.9e-43 147.6 0.0 5.8e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY01302.1 - 4e-32 111.4 0.0 6.9e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY01302.1 - 2.1e-15 57.3 0.0 3.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ORY01302.1 - 0.11 12.7 0.0 8.9 6.5 0.0 2.5 1 1 1 2 2 2 0 Flavodoxin domain zf-C2H2 PF00096.26 ORY01303.1 - 5.1e-12 45.5 17.5 1.3e-06 28.5 4.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY01303.1 - 9.7e-10 38.5 10.7 7.8e-05 23.2 2.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY01303.1 - 6.5e-08 32.7 0.4 6.5e-08 32.7 0.4 4.3 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY01303.1 - 1.5e-05 25.1 5.1 0.01 16.1 0.4 3.1 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY01303.1 - 2.1e-05 24.7 1.9 2.1e-05 24.7 1.9 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORY01303.1 - 0.00031 20.7 3.9 0.056 13.5 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY01303.1 - 0.0016 18.3 8.3 0.047 13.6 1.0 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORY01303.1 - 0.0029 17.3 2.3 0.0029 17.3 2.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain GAGA PF09237.11 ORY01303.1 - 0.0043 16.8 6.2 0.73 9.7 0.8 2.5 1 1 1 2 2 2 2 GAGA factor zinc_ribbon_9 PF14369.6 ORY01303.1 - 0.011 16.0 4.2 0.27 11.5 0.6 2.8 2 0 0 2 2 2 0 zinc-ribbon Rad50_zn_hook PF04423.14 ORY01303.1 - 0.023 14.5 3.9 0.1 12.4 0.5 2.6 1 1 1 2 2 2 0 Rad50 zinc hook motif zf_ZIC PF18366.1 ORY01303.1 - 0.03 14.4 1.0 3.9 7.7 0.2 2.6 1 1 1 2 2 2 0 Zic proteins zinc finger domain DUF2256 PF10013.9 ORY01303.1 - 0.046 13.8 1.4 6 7.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Prok-RING_1 PF14446.6 ORY01303.1 - 0.053 13.5 0.5 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TRAF6_Z2 PF18048.1 ORY01303.1 - 0.087 12.9 0.6 5.2 7.2 0.1 2.8 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Zn-C2H2_12 PF18112.1 ORY01303.1 - 0.087 13.3 2.8 1.2 9.7 0.2 3.2 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 ORY01303.1 - 0.11 12.9 7.6 0.2 12.1 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CHCC PF10276.9 ORY01303.1 - 0.12 12.4 0.6 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 ORY01303.1 - 0.16 12.0 8.6 1 9.5 0.8 2.5 1 1 1 2 2 2 0 BED zinc finger Prok-RING_4 PF14447.6 ORY01303.1 - 0.19 11.6 2.8 2.7 7.9 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 ORY01303.1 - 0.2 12.0 0.3 0.2 12.0 0.3 2.6 2 1 1 3 3 2 0 C2H2 type zinc-finger (2 copies) RNHCP PF12647.7 ORY01303.1 - 0.36 10.8 5.1 0.94 9.5 5.1 1.7 1 1 0 1 1 1 0 RNHCP domain zf-C2HE PF16278.5 ORY01303.1 - 1.6 9.2 5.3 26 5.4 0.7 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORY01303.1 - 2.2 8.1 9.2 0.13 12.1 0.6 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 ORY01303.1 - 3.1 8.0 6.3 7.5 6.8 0.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain ERG4_ERG24 PF01222.17 ORY01304.1 - 7.1e-93 311.7 21.7 8.6e-93 311.4 21.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fasciclin PF02469.22 ORY01305.1 - 1e-45 155.1 2.0 2.8e-23 82.6 0.3 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_18 PF00704.28 ORY01306.1 - 2.9e-27 96.2 0.6 1.2e-26 94.2 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Aa_trans PF01490.18 ORY01307.1 - 4.1e-60 203.6 32.0 5.1e-60 203.3 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 ORY01308.1 - 1.7e-55 188.4 28.8 2e-55 188.2 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Det1 PF09737.9 ORY01309.1 - 3.6e-105 352.4 0.9 2.2e-104 349.8 0.9 2.0 1 1 0 1 1 1 1 De-etiolated protein 1 Det1 PAP_assoc PF03828.19 ORY01309.1 - 4.3e-13 49.3 0.0 2.6e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY01309.1 - 2.6e-07 30.9 0.0 6.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY01309.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase 6PF2K PF01591.18 ORY01310.1 - 1.4e-77 260.0 0.1 1.8e-77 259.6 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY01310.1 - 4.8e-26 91.7 0.0 7.8e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY01310.1 - 4.2e-05 23.7 0.0 8.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY01310.1 - 0.057 12.9 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 ORY01310.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PAS_3 PF08447.12 ORY01312.1 - 0.0095 16.2 0.0 6.9 7.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold MPC PF03650.13 ORY01313.1 - 5.9e-41 139.1 0.5 6.3e-41 139.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers UPF0160 PF03690.13 ORY01313.1 - 0.083 12.5 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) CRC_subunit PF08624.10 ORY01314.1 - 3.8e-25 88.9 0.0 6.4e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 ORY01314.1 - 6.4e-19 67.6 50.1 9.3e-10 38.3 11.8 3.8 2 1 1 3 3 3 3 PHD-finger DUF3246 PF11596.8 ORY01314.1 - 0.0035 16.8 1.0 0.006 16.1 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) RXT2_N PF08595.11 ORY01314.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Trm112p PF03966.16 ORY01314.1 - 4.5 7.9 11.3 0.78 10.4 3.9 3.3 3 0 0 3 3 3 0 Trm112p-like protein Rad50_zn_hook PF04423.14 ORY01314.1 - 7.4 6.5 10.6 1.3 9.0 0.4 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif HAUS-augmin3 PF14932.6 ORY01315.1 - 2.5e-12 46.9 13.8 2.5e-12 46.9 13.8 4.5 1 1 2 4 4 4 1 HAUS augmin-like complex subunit 3 LOH1CR12 PF10158.9 ORY01315.1 - 0.04 13.9 9.0 1.3 9.1 0.1 4.4 3 1 0 4 4 4 0 Tumour suppressor protein DUF1664 PF07889.12 ORY01315.1 - 0.32 11.0 23.4 0.31 11.1 1.1 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 ORY01315.1 - 0.45 11.0 20.9 5.4 7.5 3.1 6.0 5 0 0 5 5 5 0 Snapin/Pallidin Nup54 PF13874.6 ORY01315.1 - 0.91 9.6 12.3 1.4 9.0 3.0 3.2 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 UCR_hinge PF02320.16 ORY01315.1 - 0.94 9.7 8.7 1.8 8.8 0.4 3.5 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein HALZ PF02183.18 ORY01315.1 - 1.4 9.2 9.5 4.3 7.6 0.1 4.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper KIP1 PF07765.12 ORY01315.1 - 1.5 9.0 13.6 12 6.1 0.2 5.2 3 1 1 4 4 4 0 KIP1-like protein LPP PF04728.13 ORY01315.1 - 4.1 7.9 10.4 0.45 10.9 0.2 4.3 4 1 0 4 4 4 0 Lipoprotein leucine-zipper Syntaxin-6_N PF09177.11 ORY01315.1 - 4.3 7.9 22.6 13 6.4 1.5 5.3 2 2 1 4 4 4 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 ORY01315.1 - 9.3 6.3 16.4 4.2 7.4 4.4 3.8 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SWIB PF02201.18 ORY01317.1 - 1.9e-16 59.7 1.2 2.5e-16 59.3 0.2 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain BicD PF09730.9 ORY01317.1 - 0.026 13.0 1.9 0.17 10.3 0.9 2.1 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF1319 PF07028.11 ORY01317.1 - 0.03 14.5 0.8 0.089 13.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) HigB-like_toxin PF05015.13 ORY01317.1 - 0.092 13.2 0.2 1 9.8 0.0 2.7 3 0 0 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB Hexokinase_2 PF03727.16 ORY01318.1 - 8.6e-73 244.7 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY01318.1 - 2.1e-66 223.6 0.0 3e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MA3 PF02847.17 ORY01318.1 - 0.15 12.1 0.0 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 MA3 domain Myb_DNA-binding PF00249.31 ORY01319.1 - 1.2e-05 25.4 0.1 2.2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY01319.1 - 0.0016 18.7 0.0 0.0045 17.2 0.0 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain S6OS1 PF15676.5 ORY01319.1 - 0.11 11.0 0.3 0.14 10.6 0.3 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Importin_rep_4 PF18808.1 ORY01320.1 - 1.6e-37 127.6 3.8 1.8e-35 121.1 0.3 4.3 3 1 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 ORY01320.1 - 5.1e-23 81.3 6.0 1.6e-06 28.4 0.0 8.9 5 2 3 9 9 9 4 HEAT repeats HEAT PF02985.22 ORY01320.1 - 3.1e-19 67.4 12.6 0.00026 21.0 0.0 11.3 12 0 0 12 12 10 3 HEAT repeat HEAT_EZ PF13513.6 ORY01320.1 - 4.4e-17 62.2 22.3 4e-08 33.6 0.0 11.4 10 1 2 12 12 12 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY01320.1 - 9.9e-14 51.7 0.4 9.3e-05 23.0 0.0 6.7 6 2 2 8 8 7 2 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 ORY01320.1 - 3.4e-13 49.7 0.3 3.4e-13 49.7 0.3 3.2 3 0 0 3 3 3 1 Importin repeat 6 DUF3385 PF11865.8 ORY01320.1 - 3.8e-12 46.4 3.4 0.0014 18.6 0.3 7.7 8 1 0 8 8 8 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 ORY01320.1 - 3.2e-09 36.8 1.0 8.8e-05 22.3 0.1 4.9 4 1 0 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 ORY01320.1 - 1.7e-06 26.9 7.5 0.00022 19.9 0.4 4.1 5 0 0 5 5 5 2 Adaptin N terminal region MMS19_C PF12460.8 ORY01320.1 - 6.9e-06 25.4 10.4 0.011 14.9 0.2 5.9 6 1 1 7 7 7 2 RNAPII transcription regulator C-terminal Arm PF00514.23 ORY01320.1 - 5.3e-05 23.1 7.4 1.2 9.3 0.0 7.8 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Importin_rep_5 PF18816.1 ORY01320.1 - 0.00011 22.4 0.0 0.00063 20.0 0.1 2.4 2 0 0 2 2 1 1 Importin repeat CLASP_N PF12348.8 ORY01320.1 - 0.00032 20.3 2.6 0.23 11.0 0.1 4.5 4 1 1 5 5 5 1 CLASP N terminal Cnd1 PF12717.7 ORY01320.1 - 0.00091 19.3 5.4 0.022 14.8 0.2 4.8 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 ORY01320.1 - 0.0037 17.2 5.4 0.091 12.7 0.2 4.3 4 1 0 4 4 4 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 ORY01320.1 - 0.0082 16.3 4.4 0.13 12.4 0.2 4.0 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 ORY01320.1 - 0.036 13.8 0.0 0.18 11.5 0.0 2.2 1 0 0 1 1 1 0 DNA alkylation repair enzyme V-ATPase_H_N PF03224.14 ORY01320.1 - 0.072 12.4 0.1 0.072 12.4 0.1 3.2 2 1 0 2 2 2 0 V-ATPase subunit H DUF5578 PF17741.1 ORY01320.1 - 2.1 7.7 5.3 5.9 6.2 0.2 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5578) Aldedh PF00171.22 ORY01321.1 - 2.6e-134 448.2 0.0 2.9e-134 448.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BLOC1S3 PF15753.5 ORY01321.1 - 0.027 14.6 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 LZ3wCH PF18517.1 ORY01321.1 - 0.045 13.8 0.1 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain LuxC PF05893.14 ORY01321.1 - 0.046 12.8 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glyco_hydro_16 PF00722.21 ORY01322.1 - 1.2e-30 106.3 6.0 2.4e-30 105.3 6.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Csm1_N PF18504.1 ORY01322.1 - 0.11 12.9 3.8 0.56 10.6 3.8 2.4 1 0 0 1 1 1 0 Csm1 N-terminal domain MCC-bdg_PDZ PF10506.9 ORY01322.1 - 0.34 10.9 7.4 0.9 9.6 4.8 2.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 ORY01322.1 - 3.2 7.9 10.4 0.27 11.3 0.6 3.5 3 0 0 3 3 3 0 bZIP transcription factor SMN PF06003.12 ORY01322.1 - 7.3 5.8 13.0 0.098 11.9 2.3 2.6 1 1 0 2 2 2 0 Survival motor neuron protein (SMN) ubiquitin PF00240.23 ORY01323.1 - 4.1e-27 93.7 0.1 4.5e-27 93.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY01323.1 - 1.3e-15 56.9 0.2 1.5e-15 56.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY01323.1 - 4.6e-05 23.8 0.0 0.00015 22.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY01323.1 - 0.0001 22.2 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY01323.1 - 0.11 12.6 0.4 3.2 7.9 0.3 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Crystall PF00030.19 ORY01375.1 - 0.0094 16.1 1.6 0.077 13.2 1.6 2.3 1 1 1 2 2 2 1 Beta/Gamma crystallin Glyco_hydro_31 PF01055.26 ORY01376.1 - 3.9e-157 524.0 2.2 5.3e-157 523.5 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY01376.1 - 4.5e-28 97.8 0.0 8.2e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY01376.1 - 3.2e-08 33.8 0.1 1.2e-07 32.0 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 ORY01376.1 - 0.05 13.9 0.7 0.14 12.4 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Nipped-B_C PF12830.7 ORY01377.1 - 2.7e-57 193.8 2.4 2.7e-57 193.8 2.4 2.8 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 ORY01377.1 - 1.7e-12 47.4 1.3 2.7e-08 33.9 0.1 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 ORY01377.1 - 0.00038 20.5 5.6 0.0073 16.4 0.5 4.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY01377.1 - 0.002 18.2 3.9 4.3 7.9 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 ORY01377.1 - 0.0036 17.7 0.4 8.9 6.8 0.2 4.2 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 ORY01377.1 - 0.006 17.1 0.1 21 5.7 0.0 4.5 3 1 1 4 4 4 0 HEAT-like repeat RFC1 PF08519.12 ORY01377.1 - 0.013 15.7 0.0 0.078 13.1 0.1 2.3 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain HTH_ParB PF17762.1 ORY01377.1 - 0.074 12.9 0.1 3.9 7.3 0.0 2.9 2 0 0 2 2 2 0 HTH domain found in ParB protein MA3 PF02847.17 ORY01377.1 - 0.081 12.9 2.3 11 6.0 0.0 4.3 4 0 0 4 4 4 0 MA3 domain FtsK_SpoIIIE PF01580.18 ORY01377.1 - 0.085 12.2 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family EXS PF03124.14 ORY01378.1 - 1.6e-72 244.6 21.3 3.7e-58 197.4 14.5 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.19 ORY01378.1 - 9.7e-44 150.8 22.7 5.6e-41 141.7 22.7 2.8 1 1 0 1 1 1 1 SPX domain DUF3376 PF11856.8 ORY01378.1 - 0.48 9.3 1.9 3 6.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3376) HMG_box PF00505.19 ORY01379.1 - 4.6e-21 75.0 3.6 5.9e-21 74.7 3.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY01379.1 - 2.3e-07 31.3 2.2 3.1e-07 30.9 2.2 1.2 1 0 0 1 1 1 1 HMG-box domain LPMO_10 PF03067.15 ORY01380.1 - 2.9e-05 24.8 0.0 5.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY01380.1 - 0.0045 16.9 0.0 0.021 14.8 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolase family 61 DUF846 PF05832.12 ORY01381.1 - 3.9e-56 188.9 14.3 4.7e-56 188.7 14.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TcpE PF12648.7 ORY01381.1 - 1.5 9.4 8.8 3.4 8.2 2.8 2.2 2 0 0 2 2 2 0 TcpE family DUF1430 PF07242.11 ORY01381.1 - 1.6 9.0 7.4 0.5 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) RseC_MucC PF04246.12 ORY01381.1 - 4.3 7.3 7.6 15 5.5 0.3 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC WD40 PF00400.32 ORY01382.1 - 3.9e-45 150.9 18.6 1.2e-08 35.4 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY01382.1 - 1.7e-06 28.3 0.4 2.2 8.7 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY01382.1 - 0.11 11.2 1.8 2.6 6.6 0.1 3.2 2 2 2 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY01382.1 - 0.14 11.5 0.0 0.5 9.7 0.0 1.9 2 1 0 2 2 2 0 WD40-like domain W_rich_C PF07483.11 ORY01382.1 - 0.14 12.3 1.7 0.58 10.3 0.4 2.4 1 1 1 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain CBS PF00571.28 ORY01383.1 - 1.3e-19 70.4 1.3 5.8e-09 36.3 0.4 2.9 3 0 0 3 3 3 2 CBS domain SIS PF01380.22 ORY01383.1 - 6.8e-16 58.3 0.0 2.4e-15 56.6 0.0 1.9 1 1 1 2 2 2 1 SIS domain SIS_2 PF13580.6 ORY01383.1 - 1.8e-05 24.8 0.0 0.082 12.9 0.0 2.5 1 1 1 2 2 2 2 SIS domain La PF05383.17 ORY01384.1 - 1.2e-25 89.3 0.1 2.6e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 ORY01384.1 - 1.1e-14 54.3 5.2 1.9e-13 50.4 0.3 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_1 PF00076.22 ORY01384.1 - 1.5e-11 44.0 3.3 1e-09 38.1 0.2 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4850 PF16142.5 ORY01384.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) CRISPR_Cas2 PF09827.9 ORY01384.1 - 0.099 12.8 0.0 3.2 8.0 0.0 2.6 1 1 1 2 2 2 0 CRISPR associated protein Cas2 PHM7_cyt PF14703.6 ORY01384.1 - 0.36 11.0 4.0 4.3 7.5 0.1 3.3 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF962 PF06127.11 ORY01385.1 - 2.7e-24 85.1 1.2 4.7e-24 84.3 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Metallophos PF00149.28 ORY01386.1 - 2.7e-16 60.7 0.0 3.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY01386.1 - 7.5e-11 42.5 0.0 1.5e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORY01386.1 - 0.0088 15.4 0.1 0.017 14.4 0.1 1.5 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily MFS_1 PF07690.16 ORY01387.1 - 1.3e-28 100.0 29.2 1.3e-28 100.0 29.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01387.1 - 1.6e-08 33.9 18.4 9.8e-05 21.4 0.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Acetyltransf_7 PF13508.7 ORY01388.1 - 7.5e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY01388.1 - 2.1e-07 31.2 0.0 3.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY01388.1 - 7.4e-07 29.2 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY01388.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FANCI_S4 PF14678.6 ORY01389.1 - 0.00072 18.8 0.6 0.001 18.3 0.1 1.5 1 1 1 2 2 2 1 FANCI solenoid 4 DUF4354 PF14263.6 ORY01389.1 - 0.0062 16.4 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4354) PC4 PF02229.16 ORY01390.1 - 1.5e-21 75.8 0.4 2.4e-21 75.1 0.4 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) HZS_alpha PF18582.1 ORY01390.1 - 0.063 13.7 0.1 0.075 13.5 0.1 1.2 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain adh_short PF00106.25 ORY01391.1 - 7.7e-43 146.2 0.6 1.1e-42 145.7 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY01391.1 - 2.4e-28 99.3 0.1 3.8e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY01391.1 - 2.4e-11 43.9 1.9 5.4e-10 39.5 1.9 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY01391.1 - 0.0031 17.0 0.1 0.0041 16.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family eIF-6 PF01912.18 ORY01391.1 - 0.22 10.9 3.0 0.23 10.8 1.6 1.7 2 1 0 2 2 2 0 eIF-6 family Alginate_lyase PF05426.12 ORY01392.1 - 4.6e-65 219.9 0.1 6e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Alginate lyase GPI-anchored PF10342.9 ORY01393.1 - 1.6e-09 38.4 0.0 2.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aa_trans PF01490.18 ORY01394.1 - 9.3e-80 268.3 39.5 1.1e-79 268.1 39.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TM_PBP2_N PF16296.5 ORY01394.1 - 0.28 11.3 1.0 0.66 10.1 1.0 1.6 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters YpmT PF17431.2 ORY01394.1 - 0.33 11.0 7.6 0.25 11.4 0.5 3.7 3 0 0 3 3 3 0 Uncharacterized YmpT-like SSF PF00474.17 ORY01395.1 - 4.7e-11 42.2 17.4 4.7e-11 42.2 17.4 2.9 2 1 0 2 2 2 1 Sodium:solute symporter family DUF4405 PF14358.6 ORY01395.1 - 0.26 11.9 0.1 0.26 11.9 0.1 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) CbtB PF09489.10 ORY01395.1 - 2.5 8.3 4.1 37 4.5 0.3 3.9 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) GATA PF00320.27 ORY01396.1 - 1.2e-11 44.0 9.5 1.2e-11 44.0 9.5 2.1 2 0 0 2 2 2 1 GATA zinc finger VGLL4 PF15245.6 ORY01396.1 - 0.59 10.2 12.2 0.26 11.3 3.2 2.6 2 1 1 3 3 3 0 Transcription cofactor vestigial-like protein 4 BRCT PF00533.26 ORY01397.1 - 0.0047 17.3 0.1 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY01397.1 - 0.092 13.2 0.1 0.2 12.1 0.0 1.7 1 1 1 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Aa_trans PF01490.18 ORY01398.1 - 8.5e-58 196.0 27.5 9.8e-58 195.8 27.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORY01398.1 - 5.4e-07 28.7 12.0 5.4e-07 28.7 12.0 3.1 2 2 0 2 2 2 1 Spore germination protein ERO1 PF04137.15 ORY01399.1 - 5e-130 433.8 0.1 5.8e-130 433.6 0.1 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) MFS_1 PF07690.16 ORY01400.1 - 3.2e-29 102.0 27.9 3.2e-29 102.0 27.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01400.1 - 5.8e-11 41.9 7.5 5.8e-11 41.9 7.5 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY01400.1 - 0.00058 18.4 1.7 0.00058 18.4 1.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PsbX PF06596.11 ORY01400.1 - 5.1 7.2 10.6 0.45 10.6 1.6 3.4 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) RhoGEF PF00621.20 ORY01401.1 - 2.1e-47 161.7 5.3 4.2e-47 160.8 5.3 1.5 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 ORY01401.1 - 1.3e-13 50.5 5.2 2.6e-06 27.1 1.3 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY01401.1 - 3.4e-13 49.5 15.2 5.1e-07 29.9 1.8 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY01401.1 - 0.014 15.8 9.5 24 6.0 0.1 6.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 ORY01401.1 - 0.015 14.8 1.5 0.044 13.3 1.5 1.9 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 ORY01401.1 - 4.2 7.7 12.8 19 5.6 0.1 5.0 5 1 1 6 6 6 0 Leucine Rich repeat MFS_1 PF07690.16 ORY01402.1 - 1e-32 113.4 29.6 1.5e-32 112.9 29.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01402.1 - 1.6e-11 43.7 8.3 3.1e-11 42.8 6.1 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter DUF5368 PF17336.2 ORY01402.1 - 0.12 12.6 2.1 0.14 12.3 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5368) MFS_3 PF05977.13 ORY01402.1 - 0.26 9.6 3.9 2.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Fasciclin PF02469.22 ORY01403.1 - 1.1e-48 164.7 0.0 1.2e-25 90.2 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain FA_desaturase PF00487.24 ORY01405.1 - 8.9e-29 101.1 25.9 1.3e-28 100.6 25.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY01405.1 - 2.8e-09 37.3 0.0 9.5e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Melibiase_2 PF16499.5 ORY01405.1 - 0.057 12.6 0.3 0.12 11.6 0.3 1.5 1 1 0 1 1 1 0 Alpha galactosidase A DUF4283 PF14111.6 ORY01405.1 - 0.064 12.8 0.5 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) HMG_box PF00505.19 ORY01407.1 - 1.5e-23 83.0 0.7 1.8e-23 82.7 0.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY01407.1 - 9.1e-10 39.0 0.3 9.1e-10 39.0 0.3 1.3 2 0 0 2 2 2 1 HMG-box domain KORA PF16509.5 ORY01407.1 - 0.076 13.3 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Ribosomal_L35Ae PF01247.18 ORY01408.1 - 1.6e-45 153.2 0.8 1.8e-45 153.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY01408.1 - 0.0039 17.4 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Ribosomal_L26 PF16906.5 ORY01409.1 - 8.6e-37 125.5 3.6 1.1e-36 125.1 3.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY01409.1 - 5e-10 39.0 1.9 5e-10 39.0 1.9 1.6 2 0 0 2 2 2 1 KOW motif CPSase_L_D2 PF02786.17 ORY01411.1 - 2e-78 262.7 0.1 3.5e-78 261.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY01411.1 - 6.2e-46 155.5 0.2 2e-45 153.8 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY01411.1 - 4.3e-36 123.3 0.0 1.2e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY01411.1 - 8.4e-17 60.8 4.0 2.1e-16 59.5 0.5 3.0 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY01411.1 - 1.2e-10 41.2 0.1 3.6e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY01411.1 - 3.2e-09 36.6 0.1 6.8e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY01411.1 - 1.8e-05 24.9 0.1 5e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY01411.1 - 0.00077 19.2 0.0 0.02 14.7 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.19 ORY01411.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 ORY01411.1 - 0.003 18.2 0.5 6.6 7.5 0.0 3.6 4 0 0 4 4 4 1 HlyD family secretion protein ATP-grasp_4 PF13535.6 ORY01411.1 - 0.025 14.2 0.1 0.074 12.6 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 ORY01411.1 - 0.043 13.0 0.0 4.6 6.4 0.0 2.5 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 ORY01411.1 - 0.058 13.3 0.1 0.88 9.5 0.1 2.4 2 0 0 2 2 2 0 Glycine cleavage H-protein Glyoxal_oxid_N PF07250.11 ORY01411.1 - 0.069 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus ATPgrasp_ST PF14397.6 ORY01411.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RNase_P_p30 PF01876.16 ORY01412.1 - 3.4e-65 219.5 0.4 4e-65 219.3 0.4 1.1 1 0 0 1 1 1 1 RNase P subunit p30 RNase_PH PF01138.21 ORY01413.1 - 4.8e-26 91.8 0.0 7.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY01413.1 - 2.7e-13 49.7 0.1 6.1e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ctr PF04145.15 ORY01414.1 - 4.4e-06 27.4 9.1 8.2e-05 23.3 2.8 2.1 1 1 1 2 2 2 2 Ctr copper transporter family VanZ PF04892.12 ORY01414.1 - 0.0034 18.0 1.9 0.0034 18.0 0.8 1.6 1 1 1 2 2 2 1 VanZ like family HSDR_N_2 PF13588.6 ORY01415.1 - 0.0023 17.9 0.3 0.0046 16.9 0.3 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Myb_DNA-bind_4 PF13837.6 ORY01453.1 - 2.1e-17 63.3 2.8 2.5e-17 63.0 2.8 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY01453.1 - 1.1e-06 28.7 2.3 1.9e-06 28.0 2.3 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY01453.1 - 3.2e-06 27.3 1.3 5.1e-06 26.6 1.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY01453.1 - 0.00013 22.2 1.6 0.0002 21.6 1.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORY01453.1 - 0.0049 17.8 1.5 0.0081 17.1 1.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORY01453.1 - 0.0098 16.0 3.9 0.019 15.0 3.9 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY01453.1 - 0.014 15.6 0.4 0.022 14.9 0.3 1.5 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DNA_pol_A_exo1 PF01612.20 ORY01454.1 - 5.5e-16 58.8 0.1 8.9e-15 54.8 0.1 2.2 1 1 0 1 1 1 1 3'-5' exonuclease RhoGEF PF00621.20 ORY01455.1 - 9.2e-27 94.4 0.1 9.8e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 ORY01456.1 - 1.2e-51 175.9 0.1 1.7e-51 175.4 0.1 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 ORY01456.1 - 3.1e-18 66.2 0.4 3.3e-09 36.9 0.1 2.3 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 ORY01456.1 - 3.8e-07 30.6 0.0 4e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 ORY01456.1 - 3.6e-05 23.6 0.9 0.00025 20.9 0.9 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 ORY01456.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 ORY01456.1 - 0.088 12.7 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 PH domain Tetraspanin PF00335.20 ORY01457.1 - 0.00011 22.0 9.1 0.00018 21.3 8.9 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 ORY01457.1 - 0.74 9.5 3.2 1 9.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Tetraspanin PF00335.20 ORY01458.1 - 0.09 12.5 6.6 0.12 12.1 6.6 1.3 1 1 0 1 1 1 0 Tetraspanin family Kei1 PF08552.11 ORY01459.1 - 0.00066 19.6 0.4 0.00066 19.6 0.4 2.4 2 1 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 ORY01459.1 - 6.6 6.4 17.2 3.1 7.4 1.8 2.2 1 1 1 2 2 2 0 Tetraspanin family DnaJ PF00226.31 ORY01460.1 - 0.00013 22.0 0.0 0.00013 22.0 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF3915 PF13054.6 ORY01460.1 - 0.11 12.5 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cyclin PF08613.11 ORY01461.1 - 5.1e-07 30.2 0.0 6.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY01461.1 - 2.5e-06 27.3 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_6 PF13516.6 ORY01462.1 - 2.6e-12 45.7 5.2 0.0018 18.2 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 ORY01462.1 - 5.2e-11 42.6 2.1 0.0013 19.0 0.0 3.7 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY01462.1 - 1.1e-05 25.3 3.6 14 6.7 0.0 5.7 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.6 ORY01462.1 - 0.011 15.5 3.2 0.18 11.6 0.5 3.3 1 1 2 3 3 3 0 Leucine rich repeat GST_N_3 PF13417.6 ORY01465.1 - 2.9e-09 37.2 0.0 4.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY01465.1 - 6.6e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY01465.1 - 2e-05 24.5 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY01465.1 - 0.00014 22.1 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY01466.1 - 4.7e-10 39.7 0.0 9.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY01466.1 - 6.7e-09 35.9 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY01466.1 - 7.3e-07 29.5 0.1 1.2e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY01466.1 - 0.00055 19.9 0.0 0.00099 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-SNAP50_C PF12251.8 ORY01467.1 - 1.3e-65 220.9 8.8 1.5e-65 220.7 8.8 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF4042 PF13251.6 ORY01467.1 - 0.097 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Abhydrolase_6 PF12697.7 ORY01468.1 - 4.1e-16 60.3 0.0 4.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY01468.1 - 4.8e-13 49.3 0.0 7.1e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY01468.1 - 2.5e-07 30.2 0.0 4.2e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORY01468.1 - 0.00066 19.5 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY01468.1 - 0.0081 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 ORY01468.1 - 0.038 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.15 ORY01468.1 - 0.18 11.0 0.0 0.42 9.7 0.0 1.5 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase PP2C PF00481.21 ORY01469.1 - 3.2e-81 272.8 0.0 3.9e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C HATPase_c PF02518.26 ORY01471.1 - 1.7e-06 28.5 0.0 2.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phosphodiest PF01663.22 ORY01472.1 - 1.5e-21 77.4 1.9 1e-19 71.4 2.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY01472.1 - 1.3e-09 37.9 0.0 3e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ORY01472.1 - 1.5e-08 34.4 0.1 2.2e-08 33.8 0.1 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Dockerin_1 PF00404.18 ORY01472.1 - 2.9e-08 33.8 3.5 5.7e-08 32.8 3.5 1.5 1 0 0 1 1 1 1 Dockerin type I domain Alk_phosphatase PF00245.20 ORY01472.1 - 0.016 14.2 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Alkaline phosphatase DUF229 PF02995.17 ORY01472.1 - 0.045 12.4 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) EF-hand_1 PF00036.32 ORY01472.1 - 0.28 10.8 0.9 12 5.7 0.0 2.6 2 0 0 2 2 2 0 EF hand Ecl1 PF12855.7 ORY01474.1 - 1.7e-06 29.3 3.9 1.8e-06 29.2 3.9 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Tetraspanin PF00335.20 ORY01475.1 - 7.3e-11 42.2 11.6 2.9e-09 37.0 12.8 2.0 1 1 1 2 2 2 2 Tetraspanin family DUF2754 PF10953.8 ORY01475.1 - 0.025 14.8 2.9 0.071 13.4 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) PspC PF04024.12 ORY01475.1 - 0.42 10.5 6.3 1 9.2 6.2 1.8 1 1 0 1 1 1 0 PspC domain Ion_trans PF00520.31 ORY01477.1 - 1.3e-05 24.6 7.4 1.4e-05 24.4 7.4 1.1 1 0 0 1 1 1 1 Ion transport protein AC_N PF16214.5 ORY01477.1 - 0.12 11.4 1.4 0.13 11.3 1.4 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Erf4 PF10256.9 ORY01478.1 - 1.4e-27 96.1 0.0 2.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1349 PF07081.11 ORY01479.1 - 9.5e-39 132.9 0.0 1.1e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 ORY01479.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain MRG PF05712.13 ORY01480.1 - 5.8e-57 192.2 3.6 5.8e-57 192.2 3.6 1.5 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 ORY01480.1 - 1.5e-09 37.6 2.4 3.2e-09 36.5 2.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4375 PF14300.6 ORY01480.1 - 0.084 13.1 0.2 0.084 13.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PWWP PF00855.17 ORY01480.1 - 0.95 9.9 5.2 0.26 11.7 1.4 2.1 3 0 0 3 3 3 0 PWWP domain Chromo PF00385.24 ORY01480.1 - 2.9 7.9 9.2 0.48 10.4 4.5 2.2 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Atrophin-1 PF03154.15 ORY01480.1 - 6.9 4.8 7.8 9.6 4.3 7.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Nuc_sug_transp PF04142.15 ORY01481.1 - 4.4e-107 357.9 12.2 5.2e-107 357.6 12.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ORY01481.1 - 1.3e-07 31.9 27.5 5.1e-05 23.5 4.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY01481.1 - 2.9e-06 26.7 15.9 5.4e-06 25.8 15.9 1.5 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 ORY01481.1 - 0.00079 18.7 9.3 0.00079 18.7 9.3 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 ORY01481.1 - 0.19 11.1 15.4 0.14 11.5 8.1 2.7 1 1 2 3 3 3 0 Triose-phosphate Transporter family TMEM234 PF10639.9 ORY01481.1 - 0.71 9.9 9.6 1.8 8.6 1.1 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 MutS_V PF00488.21 ORY01482.1 - 4.6e-76 255.0 0.1 8.3e-76 254.2 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY01482.1 - 2.4e-34 119.2 5.9 2.4e-34 119.2 5.9 2.2 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ORY01482.1 - 1.8e-23 82.9 0.0 5.5e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORY01482.1 - 6.9e-16 58.8 1.5 7.1e-15 55.5 0.2 3.1 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 ORY01482.1 - 5.5e-07 29.8 2.6 1.5e-06 28.5 1.5 2.4 2 0 0 2 2 2 1 MutS family domain IV AAA_29 PF13555.6 ORY01482.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoLip_ATPase_C PF16212.5 ORY01483.1 - 1.7e-86 290.0 20.7 1.7e-86 290.0 20.7 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY01483.1 - 5.3e-27 93.3 0.4 1.2e-25 88.9 1.2 2.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY01483.1 - 5.7e-12 45.6 0.0 2.2e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY01483.1 - 3.7e-11 42.9 0.0 3.7e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY01483.1 - 2.1e-10 41.3 0.2 0.00015 22.1 0.0 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY01483.1 - 0.0018 18.0 0.0 0.0068 16.2 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TctB PF07331.11 ORY01483.1 - 4.5 7.5 9.9 1.5 9.1 3.9 3.0 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF1345 PF07077.11 ORY01483.1 - 7.7 6.2 10.3 1.5 8.5 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) 2OG-FeII_Oxy_2 PF13532.6 ORY01484.1 - 3.8e-13 50.1 0.0 1.1e-12 48.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kp4 PF09044.10 ORY01486.1 - 1.2e-26 93.2 6.4 1.4e-26 93.0 6.4 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 ORY01486.1 - 0.024 15.4 5.4 0.13 13.1 5.4 1.9 1 1 0 1 1 1 0 Meiotically up-regulated gene family p450 PF00067.22 ORY01487.1 - 1.6e-82 277.7 0.2 2.1e-82 277.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Catalase PF00199.19 ORY01522.1 - 8.4e-184 611.1 3.1 7e-135 450.0 0.8 2.0 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 ORY01522.1 - 5.7e-22 77.7 0.1 1.4e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase PF00199.19 ORY01523.1 - 1.7e-200 666.0 0.6 1.9e-200 665.8 0.6 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY01523.1 - 5.9e-22 77.7 0.1 1.4e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive CAP PF00188.26 ORY01524.1 - 1.6e-18 67.7 0.2 2e-18 67.5 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FAD_binding_2 PF00890.24 ORY01525.1 - 4.7e-86 289.5 0.0 5.3e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY01525.1 - 5.7e-09 36.1 0.2 1.6e-08 34.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY01525.1 - 7.4e-09 35.4 3.4 1.2e-08 34.8 3.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 ORY01525.1 - 1e-08 35.2 0.7 7.7e-08 32.3 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY01525.1 - 2e-08 33.9 3.6 6.5e-07 28.9 2.7 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY01525.1 - 1.6e-06 27.5 4.8 6.2e-06 25.5 0.9 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY01525.1 - 2.5e-06 26.5 3.9 5.1e-05 22.2 0.8 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 ORY01525.1 - 5.8e-06 25.8 0.3 8.3e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY01525.1 - 2e-05 25.0 1.4 9.8e-05 22.8 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY01525.1 - 3.6e-05 23.2 0.2 6.4e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY01525.1 - 0.00026 20.3 1.6 0.0037 16.5 0.2 2.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.6 ORY01525.1 - 0.0013 18.0 0.2 0.0034 16.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY01525.1 - 0.021 15.3 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORY01525.1 - 0.023 13.8 0.7 0.035 13.2 0.7 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY01525.1 - 0.21 10.4 0.3 0.28 10.0 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 ORY01526.1 - 1.6e-44 152.9 0.0 1.9e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY01526.1 - 5.4e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY01526.1 - 0.00013 22.4 0.0 0.00061 20.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY01526.1 - 0.00038 19.8 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY01526.1 - 0.00043 19.6 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY01526.1 - 0.001 18.0 0.1 0.003 16.5 0.1 1.7 1 1 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 ORY01526.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY01526.1 - 0.0028 16.4 0.0 0.0062 15.3 0.0 1.6 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ORY01526.1 - 0.008 15.3 0.0 0.88 8.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY01526.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY01526.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORY01526.1 - 0.046 14.2 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding EccE PF11203.8 ORY01526.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Glu_dehyd_C PF16912.5 ORY01526.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 ORY01526.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 ORY01526.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 1 0 TrkA-N domain FAD_oxidored PF12831.7 ORY01526.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Bromo_TP PF07524.13 ORY01527.1 - 2.8e-12 46.5 0.2 4.9e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 ORY01527.1 - 1.7e-10 40.6 6.2 3.1e-10 39.8 6.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY01527.1 - 1.8e-08 33.7 3.7 3.3e-08 33.0 3.7 1.4 1 0 0 1 1 1 1 PHD-finger Methyltransf_15 PF09445.10 ORY01528.1 - 8.1e-43 145.9 0.0 1.3e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 ORY01528.1 - 6.1e-08 33.3 0.0 1.8e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ORY01528.1 - 2.3e-07 30.7 0.0 2e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 ORY01528.1 - 5.5e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY01528.1 - 3e-05 23.8 0.2 6.8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 ORY01528.1 - 6.8e-05 23.4 0.0 0.00022 21.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY01528.1 - 7e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY01528.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 ORY01528.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 ORY01528.1 - 0.0023 17.4 0.1 0.0061 16.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 ORY01528.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_5 PF01795.19 ORY01528.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family Methyltransf_3 PF01596.17 ORY01528.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase TrmK PF04816.12 ORY01528.1 - 0.079 12.5 0.5 0.27 10.7 0.0 2.1 3 0 0 3 3 3 0 tRNA (adenine(22)-N(1))-methyltransferase CCDC106 PF15794.5 ORY01528.1 - 0.32 10.7 10.9 1.1 8.9 10.9 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Methyltransf_32 PF13679.6 ORY01528.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Tim54 PF11711.8 ORY01528.1 - 2.5 6.8 7.2 0.11 11.3 0.7 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 ORY01528.1 - 3.1 6.0 12.6 6.3 5.0 12.6 1.4 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 ORY01528.1 - 6.4 4.9 20.7 0.29 9.4 14.9 1.5 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) tRNA-synt_1d PF00750.19 ORY01529.1 - 7.9e-98 327.6 2.7 9.5e-98 327.3 2.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY01529.1 - 3e-23 82.3 0.0 6.6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORY01529.1 - 1.8e-06 28.4 0.0 7.7e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain PIEZO PF15917.5 ORY01530.1 - 1.3 8.4 4.8 5.8 6.3 4.8 1.9 1 1 0 1 1 1 0 Piezo DUF962 PF06127.11 ORY01531.1 - 6.2e-20 71.1 0.1 1.2e-19 70.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) GET2 PF08690.10 ORY01531.1 - 0.19 11.4 0.6 0.27 10.8 0.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 HK PF02110.15 ORY01532.1 - 3.1e-82 275.7 2.7 4.7e-82 275.1 2.7 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ORY01532.1 - 4.6e-60 202.0 0.3 2.2e-59 199.8 0.1 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 ORY01532.1 - 3.2e-05 23.4 0.4 0.00013 21.4 0.1 2.0 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 ORY01532.1 - 0.00054 19.5 1.0 0.0013 18.2 1.0 1.7 1 1 1 2 2 2 1 Carbohydrate kinase Synaptobrevin PF00957.21 ORY01533.1 - 2.8e-27 94.3 4.0 3.3e-27 94.1 4.0 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.17 ORY01533.1 - 0.0093 15.9 0.7 0.045 13.7 0.7 1.8 1 1 0 1 1 1 1 Retroviral envelope protein NPV_P10 PF05531.12 ORY01533.1 - 0.024 15.1 0.5 0.032 14.7 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Pex26 PF07163.12 ORY01533.1 - 0.033 13.5 0.3 0.039 13.3 0.3 1.0 1 0 0 1 1 1 0 Pex26 protein GIT1_C PF12205.8 ORY01533.1 - 0.033 14.3 0.4 0.039 14.1 0.4 1.1 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term NEXCaM_BD PF16644.5 ORY01533.1 - 0.045 14.0 0.2 0.052 13.8 0.2 1.1 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin DUF2207 PF09972.9 ORY01533.1 - 0.058 12.1 0.0 0.058 12.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 ORY01533.1 - 0.079 13.0 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SNARE PF05739.19 ORY01533.1 - 3.2 7.8 12.9 0.23 11.5 6.9 2.2 2 2 0 2 2 2 0 SNARE domain dCMP_cyt_deam_1 PF00383.23 ORY01535.1 - 5e-25 87.3 0.1 6.5e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY01535.1 - 1.2e-21 76.9 0.0 1.5e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORY01535.1 - 0.017 15.2 0.2 0.033 14.2 0.2 1.4 1 1 0 1 1 1 0 Bd3614-like deaminase Aminoglyc_resit PF10706.9 ORY01535.1 - 0.1 12.3 0.2 3.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Aminoglycoside-2''-adenylyltransferase SNAD4 PF18750.1 ORY01535.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Snf7 PF03357.21 ORY01536.1 - 1.3e-16 60.7 9.9 1.5e-16 60.5 9.9 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 ORY01536.1 - 0.0069 16.3 2.7 0.011 15.7 2.7 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SYCE1 PF15233.6 ORY01536.1 - 0.0089 16.1 4.4 0.017 15.2 4.4 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 FAM117 PF15388.6 ORY01536.1 - 0.012 15.0 0.9 0.018 14.5 0.9 1.2 1 0 0 1 1 1 0 Protein Family FAM117 DMSP_lyase PF16867.5 ORY01536.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase adh_short PF00106.25 ORY01537.1 - 9.3e-21 74.2 0.0 1.4e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY01537.1 - 2.6e-09 37.0 0.0 5.1e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase S_100 PF01023.19 ORY01538.1 - 0.075 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Thiolase_N PF00108.23 ORY01539.1 - 1.8e-92 309.3 1.3 1.8e-92 309.3 1.3 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY01539.1 - 7.2e-46 154.8 0.7 1.7e-45 153.6 0.7 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY01539.1 - 1.3e-05 24.9 0.7 1.3e-05 24.9 0.7 3.3 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY01539.1 - 0.00053 19.8 4.5 0.031 14.1 0.1 3.3 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF348 PF03990.14 ORY01539.1 - 0.07 12.9 0.6 13 5.6 0.0 3.5 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain V_ATPase_I PF01496.19 ORY01540.1 - 0 1056.6 0.0 0 1056.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Baculo_p24 PF05073.12 ORY01540.1 - 0.017 14.9 2.3 0.33 10.7 0.2 2.3 2 0 0 2 2 2 0 Baculovirus P24 capsid protein THP2 PF09432.10 ORY01540.1 - 0.15 12.1 2.1 0.86 9.7 0.2 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 MutS_III PF05192.18 ORY01540.1 - 0.24 11.6 3.3 0.69 10.1 3.2 1.7 1 1 0 1 1 1 0 MutS domain III DASH_Dam1 PF08653.10 ORY01540.1 - 3.2 7.6 7.4 17 5.3 0.4 4.1 5 0 0 5 5 5 0 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.9 ORY01540.1 - 3.9 7.5 6.8 13 5.8 0.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Muted PF14942.6 ORY01540.1 - 5.3 7.4 6.8 17 5.7 1.9 2.4 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Cortex-I_coil PF09304.10 ORY01540.1 - 6.8 7.0 7.4 1.3 9.3 0.8 2.5 3 0 0 3 3 3 0 Cortexillin I, coiled coil Laminin_G_3 PF13385.6 ORY01541.1 - 4.5e-08 33.4 0.0 9.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 ORY01541.1 - 9.6e-07 28.3 14.7 0.00018 20.9 1.6 6.8 5 1 1 6 6 6 1 Domain of unknown function (DUF4704) MOR2-PAG1_C PF14225.6 ORY01541.1 - 0.00043 20.2 0.1 0.00043 20.2 0.1 3.8 5 0 0 5 5 5 1 Cell morphogenesis C-terminal Atx10homo_assoc PF09759.9 ORY01541.1 - 0.0024 17.9 2.2 6.6 6.8 0.0 6.3 9 0 0 9 9 9 1 Spinocerebellar ataxia type 10 protein domain CDC14 PF08045.11 ORY01541.1 - 0.0059 15.7 0.8 0.046 12.8 0.8 2.7 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Arm PF00514.23 ORY01541.1 - 0.042 13.9 4.3 6.7 6.9 0.0 5.9 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DUF5526 PF17664.1 ORY01541.1 - 8.8 5.9 10.2 7 6.2 7.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Arf PF00025.21 ORY01542.1 - 2.8e-71 238.6 1.3 3.2e-71 238.4 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY01542.1 - 1.4e-12 47.9 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY01542.1 - 2.3e-11 43.6 0.0 2.7e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY01542.1 - 2.5e-11 43.3 1.9 1.3e-05 24.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY01542.1 - 6.6e-11 42.0 0.0 8.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY01542.1 - 1e-09 38.1 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY01542.1 - 4.2e-07 30.0 0.0 7.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY01542.1 - 4.6e-05 23.0 0.0 0.00035 20.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 ORY01542.1 - 0.013 14.4 0.1 0.039 12.9 0.1 1.8 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ORY01542.1 - 0.015 15.3 0.4 0.06 13.3 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ORY01542.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PPK2 PF03976.14 ORY01542.1 - 0.12 11.9 0.2 3.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) ATP-synt_ab PF00006.25 ORY01543.1 - 7.7e-62 208.7 0.0 1.2e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY01543.1 - 3.1e-22 78.8 0.9 7.1e-22 77.7 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ORY01543.1 - 0.015 14.7 0.3 0.03 13.7 0.3 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ORY01543.1 - 0.026 13.7 0.8 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 ORY01543.1 - 0.059 13.7 0.8 0.45 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY01543.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORY01543.1 - 0.069 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 ORY01543.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Med2 PF11214.8 ORY01543.1 - 0.14 12.4 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 RNA_helicase PF00910.22 ORY01543.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PAP_assoc PF03828.19 ORY01546.1 - 1e-18 67.3 0.2 3.4e-18 65.6 0.1 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY01546.1 - 6.2e-07 29.6 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY01546.1 - 0.0031 17.6 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RRM_1 PF00076.22 ORY01547.1 - 1e-70 233.5 4.3 6.5e-20 70.7 0.1 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY01547.1 - 2.2e-24 85.1 0.0 1.2e-08 34.7 0.0 4.5 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY01547.1 - 8.7e-12 44.7 0.0 0.045 13.4 0.0 4.4 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY01547.1 - 3.4e-11 43.0 1.2 0.00093 19.2 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif NRDE-2 PF08424.10 ORY01547.1 - 4.3e-08 32.7 14.0 0.034 13.3 0.5 5.3 1 1 3 4 4 4 4 NRDE-2, necessary for RNA interference DUF1866 PF08952.11 ORY01547.1 - 0.00026 20.9 0.0 1 9.2 0.0 3.9 2 1 2 4 4 4 1 Domain of unknown function (DUF1866) RRM_7 PF16367.5 ORY01547.1 - 0.00032 20.8 0.3 52 4.0 0.0 5.9 6 0 0 6 6 6 0 RNA recognition motif RRM_Rrp7 PF17799.1 ORY01547.1 - 0.00039 20.3 1.6 0.026 14.3 0.0 3.9 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain U3_assoc_6 PF08640.11 ORY01547.1 - 0.069 13.2 13.9 0.49 10.5 0.1 4.3 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DUF3887 PF13026.6 ORY01547.1 - 0.18 12.6 13.1 2.1 9.2 1.5 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3887) GAGA_bind PF06217.12 ORY01547.1 - 0.57 10.4 7.7 1.8 8.8 7.7 1.8 1 0 0 1 1 1 0 GAGA binding protein-like family GATA PF00320.27 ORY01548.1 - 4.8e-14 51.7 8.0 8.9e-14 50.8 8.0 1.5 1 0 0 1 1 1 1 GATA zinc finger CNDH2_C PF16858.5 ORY01548.1 - 0.0092 15.9 1.9 0.013 15.4 1.9 1.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pam17 PF08566.10 ORY01549.1 - 0.033 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF2207 PF09972.9 ORY01549.1 - 0.067 11.9 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kinesin PF00225.23 ORY01550.1 - 5.1e-104 347.8 0.1 5.1e-104 347.8 0.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY01550.1 - 2.2e-57 193.2 0.0 2.2e-57 193.2 0.0 2.2 2 1 0 2 2 1 1 Microtubule binding TelA PF05816.11 ORY01550.1 - 0.00031 19.9 12.7 0.00064 18.9 12.7 1.5 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF16 PF01519.16 ORY01550.1 - 0.0027 18.2 10.0 0.0027 18.2 10.0 3.6 1 1 2 3 3 3 1 Protein of unknown function DUF16 IFT57 PF10498.9 ORY01550.1 - 0.008 15.2 19.8 0.008 15.2 19.8 2.2 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 ORY01550.1 - 0.011 15.8 11.5 0.025 14.6 1.0 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 ORY01550.1 - 0.02 13.1 28.7 0.0078 14.5 25.7 1.8 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 ORY01550.1 - 0.027 14.1 27.1 0.19 11.3 20.3 3.1 1 1 2 3 3 3 0 Intermediate filament protein Tektin PF03148.14 ORY01550.1 - 0.033 13.0 25.5 0.028 13.2 20.8 2.4 1 1 1 2 2 2 0 Tektin family Cast PF10174.9 ORY01550.1 - 0.033 12.4 24.3 0.048 11.9 24.3 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HrpB7 PF09486.10 ORY01550.1 - 0.04 14.3 9.6 0.2 12.1 4.7 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TACC_C PF05010.14 ORY01550.1 - 0.044 13.6 26.2 0.071 12.9 25.7 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YabA PF06156.13 ORY01550.1 - 0.094 13.4 19.9 1.1e+02 3.5 9.0 5.4 3 1 1 4 4 4 0 Initiation control protein YabA Spc7 PF08317.11 ORY01550.1 - 0.19 10.6 31.3 0.067 12.1 18.0 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein Tup_N PF08581.10 ORY01550.1 - 0.21 11.9 26.2 0.076 13.3 10.4 4.1 1 1 3 4 4 4 0 Tup N-terminal Atg14 PF10186.9 ORY01550.1 - 0.28 10.2 25.8 0.75 8.8 25.8 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIVA PF05103.13 ORY01550.1 - 0.29 11.2 19.4 0.068 13.3 14.6 2.4 1 1 1 2 2 2 0 DivIVA protein KxDL PF10241.9 ORY01550.1 - 0.34 11.2 19.4 0.31 11.4 2.0 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein Nup54 PF13874.6 ORY01550.1 - 0.38 10.9 16.5 0.15 12.1 13.3 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 BicD PF09730.9 ORY01550.1 - 0.4 9.0 27.1 0.23 9.8 24.8 1.6 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D COG5 PF10392.9 ORY01550.1 - 0.59 10.3 20.6 0.3 11.2 15.3 3.0 2 1 0 3 3 2 0 Golgi transport complex subunit 5 AAA_16 PF13191.6 ORY01550.1 - 0.6 10.5 3.8 0.91 9.9 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain Fib_alpha PF08702.10 ORY01550.1 - 0.63 10.2 25.6 33 4.6 20.5 4.1 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DUF3552 PF12072.8 ORY01550.1 - 0.69 9.3 24.1 4 6.8 24.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) KASH_CCD PF14662.6 ORY01550.1 - 0.71 9.7 26.6 2.4 7.9 26.6 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 ORY01550.1 - 0.78 9.9 30.2 4.5 7.4 30.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 ORY01550.1 - 1 9.4 30.2 0.3 11.2 22.3 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPA PF16469.5 ORY01550.1 - 1.4 9.5 15.6 0.25 11.9 9.8 2.7 2 1 0 2 2 1 0 Nematode polyprotein allergen ABA-1 APG6_N PF17675.1 ORY01550.1 - 1.8 9.1 31.1 0.63 10.6 23.7 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ApoO PF09769.9 ORY01550.1 - 2 8.4 7.8 0.76 9.7 1.2 2.8 1 1 2 3 3 3 0 Apolipoprotein O SOAR PF16533.5 ORY01550.1 - 2.1 8.4 14.0 0.7 9.9 7.3 2.7 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF724 PF05266.14 ORY01550.1 - 2.2 8.1 24.8 3.2 7.5 0.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DLP_helical PF18709.1 ORY01550.1 - 2.3 7.3 17.2 1.9 7.6 3.5 3.2 1 1 2 3 3 3 0 Dynamin-like helical domain MscS_porin PF12795.7 ORY01550.1 - 2.5 7.6 31.4 0.1 12.1 24.0 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.19 ORY01550.1 - 2.5 5.8 28.1 0.64 7.7 14.7 2.0 1 1 0 1 1 1 0 Myosin tail Golgin_A5 PF09787.9 ORY01550.1 - 2.9 7.3 30.4 1.1 8.6 18.1 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 ORY01550.1 - 2.9 7.9 29.3 0.21 11.6 21.3 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 ORY01550.1 - 3.1 7.9 17.0 1.9 8.5 9.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 ORY01550.1 - 3.5 6.4 30.7 16 4.3 30.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FAM184 PF15665.5 ORY01550.1 - 3.6 7.3 29.9 0.026 14.3 13.5 3.0 2 1 0 3 3 1 0 Family with sequence similarity 184, A and B HIP1_clath_bdg PF16515.5 ORY01550.1 - 3.7 8.2 30.4 0.55 10.9 10.1 3.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 EzrA PF06160.12 ORY01550.1 - 3.7 5.6 25.4 7.3 4.6 24.2 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4600 PF15372.6 ORY01550.1 - 3.8 8.0 23.1 13 6.3 5.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Prominin PF05478.11 ORY01550.1 - 4 5.3 25.8 0.55 8.1 19.7 1.9 1 1 1 2 2 2 0 Prominin YtxH PF12732.7 ORY01550.1 - 4.3 8.0 7.7 26 5.4 0.1 3.2 2 2 1 3 3 2 0 YtxH-like protein BST2 PF16716.5 ORY01550.1 - 4.4 7.9 32.7 16 6.2 0.2 4.0 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Rho_Binding PF08912.11 ORY01550.1 - 4.9 8.0 26.5 0.53 11.1 3.5 4.8 3 1 1 4 4 2 0 Rho Binding DUF489 PF04356.12 ORY01550.1 - 5.3 7.0 11.4 7.6 6.5 7.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF489) HalX PF08663.10 ORY01550.1 - 5.9 7.3 10.0 1.6e+02 2.7 8.1 3.6 2 1 0 2 2 1 0 HalX domain YlqD PF11068.8 ORY01550.1 - 6.8 7.1 24.9 1 9.7 18.8 2.7 1 1 2 3 3 3 0 YlqD protein GAS PF13851.6 ORY01550.1 - 7.5 5.8 28.9 8.2 5.7 21.1 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fungal_TACC PF12709.7 ORY01550.1 - 7.8 7.0 24.1 2 8.9 2.7 3.9 3 1 1 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ABC_tran_CTD PF16326.5 ORY01550.1 - 8 6.8 25.4 1.6 9.1 1.4 5.1 2 1 3 5 5 5 0 ABC transporter C-terminal domain TRAM_LAG1_CLN8 PF03798.16 ORY01551.1 - 2e-41 141.9 26.2 2e-41 141.9 26.2 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORY01551.1 - 3e-13 49.2 0.3 1e-12 47.5 0.3 2.0 1 0 0 1 1 1 1 TRAM1-like protein AAA PF00004.29 ORY01552.1 - 1.4e-38 132.3 0.0 3.3e-38 131.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY01552.1 - 3.8e-14 52.2 0.0 1.2e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 ORY01552.1 - 2.5e-08 33.8 0.1 8.9e-08 32.0 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 ORY01552.1 - 7e-05 23.0 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY01552.1 - 9.8e-05 22.2 0.0 0.00029 20.6 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY01552.1 - 0.0004 20.4 0.0 0.0035 17.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY01552.1 - 0.00053 20.3 0.2 0.0047 17.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY01552.1 - 0.00062 20.2 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 ORY01552.1 - 0.00067 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY01552.1 - 0.004 16.6 0.0 0.0094 15.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY01552.1 - 0.004 17.3 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY01552.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 ORY01552.1 - 0.016 15.0 0.1 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY01552.1 - 0.016 14.5 0.0 0.46 9.8 0.1 2.4 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.6 ORY01552.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY01552.1 - 0.024 14.3 0.0 0.31 10.7 0.0 2.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORY01552.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY01552.1 - 0.041 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY01552.1 - 0.044 14.2 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 ORY01552.1 - 0.051 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY01552.1 - 0.054 14.0 0.0 0.054 14.0 0.0 2.3 3 0 0 3 3 1 0 AAA domain DUF2075 PF09848.9 ORY01552.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ORY01552.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TPR_11 PF13414.6 ORY01552.1 - 0.069 12.8 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 TPR repeat NTPase_1 PF03266.15 ORY01552.1 - 0.085 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 ORY01552.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 ORY01552.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 ORY01552.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ORY01552.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 ORY01552.1 - 0.19 10.8 0.1 0.56 9.3 0.1 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TPR_2 PF07719.17 ORY01552.1 - 1.7 8.9 4.3 0.96 9.7 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Atg29_N PF18388.1 ORY01553.1 - 1.4e-13 50.4 2.4 2.4e-13 49.7 2.4 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain rRNA_processing PF08524.11 ORY01553.1 - 0.28 11.2 5.1 0.61 10.1 5.1 1.7 1 1 0 1 1 1 0 rRNA processing GATA PF00320.27 ORY01554.1 - 2.8e-28 97.2 14.2 7.5e-15 54.3 2.2 2.2 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY01554.1 - 9.2e-06 25.1 3.9 0.00014 21.3 0.1 2.4 2 1 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.7 ORY01554.1 - 2.3e-05 24.3 2.5 0.031 14.3 0.5 2.8 1 1 1 2 2 2 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORY01554.1 - 4.4e-05 23.3 4.1 0.0095 15.8 0.2 2.1 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 ORY01554.1 - 0.0039 17.3 4.4 0.041 14.1 0.4 2.3 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 ORY01554.1 - 0.0098 16.0 2.0 0.33 11.1 0.2 2.3 2 0 0 2 2 2 1 Zinc ribbon domain ArfGap PF01412.18 ORY01554.1 - 0.01 15.9 4.5 0.034 14.2 0.3 2.1 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 ORY01554.1 - 0.016 15.1 4.2 0.12 12.2 0.4 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NMD3 PF04981.13 ORY01554.1 - 0.08 12.4 2.0 2.2 7.7 0.0 2.0 1 1 1 2 2 2 0 NMD3 family ZF-HD_dimer PF04770.12 ORY01554.1 - 0.085 13.2 6.2 0.39 11.1 0.1 2.9 2 1 0 2 2 2 0 ZF-HD protein dimerisation region zf-Sec23_Sec24 PF04810.15 ORY01554.1 - 0.087 12.9 1.9 0.087 12.9 1.9 2.8 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 ORY01554.1 - 1 8.9 14.4 2.3 7.8 0.4 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Vps36-NZF-N PF16988.5 ORY01554.1 - 1.1 8.7 9.6 8 5.9 0.5 3.1 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FYVE PF01363.21 ORY01554.1 - 1.7 8.9 6.9 8.7 6.6 1.5 2.4 2 1 0 2 2 2 0 FYVE zinc finger zf-RRN7 PF11781.8 ORY01554.1 - 3.1 7.6 9.7 0.4 10.4 0.6 3.3 2 2 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PHD PF00628.29 ORY01554.1 - 4 7.4 9.6 1.9 8.4 0.6 2.6 2 1 0 2 2 2 0 PHD-finger ALMT PF11744.8 ORY01555.1 - 4.6e-17 62.0 8.2 8.9e-17 61.1 8.2 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.6 ORY01555.1 - 2.6e-13 50.2 11.7 5.7e-13 49.1 11.7 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY01555.1 - 2.3e-07 29.8 2.5 2.3e-07 29.8 2.5 1.9 1 1 1 2 2 2 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 ORY01555.1 - 0.002 17.2 2.3 0.002 17.2 2.3 1.8 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC-like PF12805.7 ORY01555.1 - 0.33 10.0 3.0 0.72 8.9 3.0 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Spore_YabQ PF09578.10 ORY01555.1 - 0.76 10.0 8.9 6.6 7.0 0.4 3.3 3 0 0 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) Snapin_Pallidin PF14712.6 ORY01556.1 - 2.1e-19 69.7 0.8 2.1e-19 69.7 0.8 1.4 2 0 0 2 2 2 1 Snapin/Pallidin Het-C PF07217.11 ORY01556.1 - 0.00039 19.1 0.8 0.00043 18.9 0.8 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cast PF10174.9 ORY01556.1 - 0.0095 14.2 0.2 0.012 13.9 0.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF3450 PF11932.8 ORY01556.1 - 0.011 15.1 0.9 0.011 15.1 0.9 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 ORY01556.1 - 0.032 14.5 1.5 2.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Vps51 PF08700.11 ORY01556.1 - 0.043 13.9 0.7 0.22 11.6 0.4 2.2 1 1 1 2 2 2 0 Vps51/Vps67 DUF5082 PF16888.5 ORY01556.1 - 0.068 13.4 1.8 0.41 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 ORY01556.1 - 0.32 11.4 4.3 3.1 8.3 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 ORY01556.1 - 6.8 7.2 7.2 6.8 7.2 4.1 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 MCM PF00493.23 ORY01557.1 - 1.6e-97 325.0 0.0 2.8e-97 324.2 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY01557.1 - 9.2e-39 132.2 0.2 1.6e-38 131.4 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY01557.1 - 1e-28 99.6 2.6 1.7e-28 98.9 1.9 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 ORY01557.1 - 5.9e-16 58.9 1.7 5.9e-16 58.9 1.7 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 ORY01557.1 - 5.2e-08 33.0 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY01557.1 - 3.4e-06 26.6 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY01557.1 - 0.00094 19.0 0.0 0.0046 16.8 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY01557.1 - 0.0051 17.2 0.0 0.026 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 ORY01557.1 - 0.0077 16.0 0.0 2.9 7.6 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain RasGEF PF00617.19 ORY01558.1 - 1.7e-52 178.2 1.0 4.4e-52 176.9 1.0 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY01558.1 - 6.3e-23 81.0 0.0 1.8e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Branch PF02485.21 ORY01558.1 - 0.07 12.6 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 Core-2/I-Branching enzyme RasGEF PF00617.19 ORY01559.1 - 8.5e-56 188.9 0.5 1.8e-55 187.9 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY01559.1 - 2.9e-22 78.9 2.4 4.6e-22 78.2 0.8 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_2 PF07653.17 ORY01559.1 - 8.4e-12 44.6 0.1 1.9e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY01559.1 - 9.3e-11 41.2 0.0 2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY01559.1 - 7.8e-09 35.3 0.2 2.2e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 ORY01559.1 - 0.00021 21.3 3.2 0.00021 21.3 3.2 2.2 2 0 0 2 2 2 1 WW domain PLU-1 PF08429.11 ORY01559.1 - 1.8 7.7 8.4 0.51 9.5 0.5 3.0 3 0 0 3 3 3 0 PLU-1-like protein WD40 PF00400.32 ORY01560.1 - 4.4e-11 43.2 6.4 0.00057 20.6 0.4 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nop53 PF07767.11 ORY01561.1 - 3.7e-84 283.4 50.4 4.4e-84 283.2 50.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BOF PF04076.13 ORY01561.1 - 0.011 15.7 0.3 0.041 13.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein RRM_1 PF00076.22 ORY01562.1 - 1.2e-17 63.5 0.0 1.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY01562.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif MMgT PF10270.9 ORY01563.1 - 7.7e-12 45.4 0.1 1.4e-11 44.6 0.1 1.4 1 1 0 1 1 1 1 Membrane magnesium transporter PepSY_TM_like_2 PF16357.5 ORY01564.1 - 0.059 13.3 0.2 0.1 12.6 0.1 1.5 1 1 0 1 1 1 0 Putative PepSY_TM-like DUF3340 PF11818.8 ORY01564.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF4448 PF14610.6 ORY01565.1 - 0.0075 16.1 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Cyclin PF08613.11 ORY01566.1 - 3e-08 34.2 0.0 3.6e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY01566.1 - 1.7e-06 27.8 0.0 1.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydro_16 PF00722.21 ORY01596.1 - 1.1e-14 54.3 0.1 1.4e-14 54.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_S8 PF00082.22 ORY01597.1 - 1.4e-32 113.2 21.0 2.7e-32 112.2 21.0 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY01597.1 - 0.00067 20.3 0.4 0.0057 17.3 0.1 2.3 1 1 1 2 2 2 1 Peptidase inhibitor I9 Argos PF11581.8 ORY01598.1 - 0.095 12.7 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Polysacc_deac_1 PF01522.21 ORY01599.1 - 3.5e-28 98.0 0.0 5.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORY01599.1 - 0.056 13.1 0.0 0.089 12.4 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 ORY01600.1 - 1e-27 96.5 0.0 1.5e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY01600.1 - 2e-19 69.8 81.0 1.3e-06 28.8 20.7 3.8 3 0 0 3 3 3 3 Chitin recognition protein Isochorismatase PF00857.20 ORY01601.1 - 2.8e-20 73.2 0.0 5.6e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 ORY01602.1 - 2.4e-20 73.5 0.0 4.7e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Polysacc_deac_1 PF01522.21 ORY01603.1 - 1.9e-26 92.4 0.0 2.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY01603.1 - 0.00018 21.9 21.9 0.00018 21.9 21.9 1.9 2 0 0 2 2 2 1 Chitin recognition protein DUF2334 PF10096.9 ORY01603.1 - 0.053 13.2 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 ORY01604.1 - 6.7e-27 93.8 0.0 9.6e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORY01604.1 - 0.055 13.1 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 ORY01605.1 - 1.5e-28 99.1 0.0 1.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ORY01605.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 ORY01606.1 - 5.5e-27 94.1 0.0 8.6e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY01606.1 - 1.7e-18 66.8 80.9 2.3e-07 31.2 22.4 4.2 3 1 1 4 4 4 3 Chitin recognition protein Apt1 PF10351.9 ORY01606.1 - 0.023 13.6 2.1 0.028 13.3 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt20 PF12090.8 ORY01606.1 - 2.3 7.8 12.0 3.5 7.2 12.0 1.2 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.19 ORY01607.1 - 2.9e-27 95.1 11.3 3.4e-27 94.8 11.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ABC_membrane PF00664.23 ORY01608.1 - 4.2e-124 413.6 33.4 1e-67 228.7 10.9 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY01608.1 - 7.6e-72 240.2 0.0 5.1e-35 121.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY01608.1 - 1.6e-13 50.6 0.1 1.3e-05 24.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY01608.1 - 4.4e-07 29.5 1.4 0.0087 15.8 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY01608.1 - 5.3e-07 30.2 0.4 0.037 14.4 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 ORY01608.1 - 1.3e-06 27.5 0.6 0.0049 15.7 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ORY01608.1 - 1.1e-05 25.5 1.6 0.14 12.1 0.0 3.6 4 0 0 4 4 4 2 RsgA GTPase AAA_21 PF13304.6 ORY01608.1 - 1.5e-05 25.0 0.4 0.049 13.4 0.1 3.7 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY01608.1 - 5.4e-05 23.5 1.7 0.51 10.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORY01608.1 - 7.1e-05 22.7 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY01608.1 - 0.0005 20.6 0.0 0.48 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY01608.1 - 0.00053 19.8 0.1 1.3 8.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY01608.1 - 0.00058 19.9 0.2 1.9 8.5 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 ORY01608.1 - 0.0017 18.3 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 ORY01608.1 - 0.0019 18.4 2.6 3.2 8.1 0.4 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 ORY01608.1 - 0.0035 17.8 3.7 3.6 8.0 0.3 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY01608.1 - 0.0036 16.9 0.0 3 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY01608.1 - 0.0037 16.8 0.0 0.91 9.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 ORY01608.1 - 0.0037 17.4 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY01608.1 - 0.004 17.7 0.2 1.4 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY01608.1 - 0.0048 16.2 0.1 2.1 7.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 ORY01608.1 - 0.0051 16.7 0.2 1.5 8.7 0.0 3.2 3 0 0 3 3 3 1 Adenylylsulphate kinase G-alpha PF00503.20 ORY01608.1 - 0.011 15.0 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 ORY01608.1 - 0.016 15.4 0.4 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY01608.1 - 0.017 14.5 0.1 0.42 10.0 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 ORY01608.1 - 0.017 15.2 0.0 2.6 8.2 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase WCOR413 PF05562.11 ORY01608.1 - 0.037 14.0 0.3 0.12 12.3 0.2 1.8 2 0 0 2 2 1 0 Cold acclimation protein WCOR413 NB-ARC PF00931.22 ORY01608.1 - 0.047 12.9 0.1 2.4 7.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain PRK PF00485.18 ORY01608.1 - 0.047 13.4 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 ORY01608.1 - 0.049 14.0 0.1 15 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase CsbD PF05532.12 ORY01609.1 - 8.5e-19 67.2 16.4 1.1e-09 38.1 5.7 2.2 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01610.1 - 8.9e-23 79.9 20.0 5e-12 45.5 6.0 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01610.1 - 0.08 13.1 0.6 0.13 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01611.1 - 9e-23 79.9 20.1 5e-12 45.5 6.1 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01611.1 - 0.086 13.0 0.6 0.14 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01612.1 - 9e-23 79.9 20.1 5e-12 45.5 6.1 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01612.1 - 0.086 13.0 0.6 0.14 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01613.1 - 1.5e-22 79.3 10.9 2.8e-11 43.1 4.9 2.0 2 0 0 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01614.1 - 9e-23 79.9 20.1 5e-12 45.5 6.1 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01614.1 - 0.086 13.0 0.6 0.14 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01615.1 - 8.9e-23 79.9 20.0 5e-12 45.5 6.0 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01615.1 - 0.08 13.1 0.6 0.13 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01616.1 - 4.7e-21 74.5 18.9 5e-12 45.5 6.1 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01616.1 - 0.084 13.1 0.6 0.14 12.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01617.1 - 8.4e-19 67.2 15.1 9.2e-12 44.7 5.4 2.1 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01618.1 - 1.7e-05 24.6 0.2 2.5e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 CsbD-like CsbD PF05532.12 ORY01619.1 - 1.1e-19 70.0 13.0 3.2e-12 46.1 7.3 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01620.1 - 1.8e-22 79.0 17.5 4.9e-12 45.6 7.2 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01621.1 - 1.8e-22 79.0 17.5 5.3e-12 45.5 7.3 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01622.1 - 4.4e-22 77.7 19.1 4.9e-12 45.6 7.2 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01623.1 - 1.5e-22 79.2 16.2 4.2e-12 45.8 5.9 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01624.1 - 1.9e-22 78.9 17.7 6.9e-12 45.1 7.7 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01625.1 - 1.6e-22 79.1 16.8 4.4e-12 45.7 6.5 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01626.1 - 1.2e-22 79.5 16.8 3.3e-12 46.1 6.5 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01627.1 - 1.8e-22 79.0 17.5 4.9e-12 45.6 7.2 2.0 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 ORY01628.1 - 8.5e-23 80.0 20.8 4.8e-12 45.6 6.9 2.0 1 1 1 2 2 2 2 CsbD-like DUF4148 PF13663.6 ORY01628.1 - 0.091 13.0 0.7 0.15 12.3 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) CsbD PF05532.12 ORY01629.1 - 3e-23 81.5 19.0 1.4e-12 47.3 5.0 2.0 1 1 1 2 2 2 2 CsbD-like DUF3292 PF11696.8 ORY01629.1 - 0.71 8.2 3.2 0.76 8.1 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PX PF00787.24 ORY01630.1 - 9.2e-24 83.6 0.9 9.2e-24 83.6 0.9 2.2 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 ORY01630.1 - 2.6e-14 53.3 16.5 1.1e-07 31.7 2.3 2.3 1 1 1 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 ORY01630.1 - 0.0019 17.9 12.4 0.036 13.8 4.5 3.2 1 1 0 2 2 2 1 BAR domain of APPL family Snurportin1 PF11538.8 ORY01630.1 - 0.0059 16.8 2.6 0.24 11.6 0.1 3.1 2 0 0 2 2 2 1 Snurportin1 DUF4164 PF13747.6 ORY01630.1 - 0.013 15.7 5.8 0.064 13.5 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) SpecificRecomb PF10136.9 ORY01630.1 - 0.014 13.7 3.7 0.022 13.1 1.4 1.9 1 1 1 2 2 2 0 Site-specific recombinase DUF4665 PF15679.5 ORY01630.1 - 0.026 15.1 3.2 0.056 14.1 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) DASH_Dam1 PF08653.10 ORY01630.1 - 0.044 13.6 0.4 0.39 10.6 0.2 2.6 1 1 1 2 2 2 0 DASH complex subunit Dam1 LemA PF04011.12 ORY01630.1 - 0.054 13.4 1.7 0.37 10.6 0.0 2.9 2 2 1 3 3 3 0 LemA family DUF4685 PF15737.5 ORY01630.1 - 0.07 13.6 0.8 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) YusW PF14039.6 ORY01630.1 - 0.11 13.0 4.7 0.22 12.1 0.6 2.5 2 0 0 2 2 2 0 YusW-like protein BLOC1_2 PF10046.9 ORY01630.1 - 0.42 10.9 8.9 7.6 6.9 2.7 3.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.15 ORY01630.1 - 0.51 10.2 8.7 0.081 12.8 3.0 2.5 2 2 0 2 2 2 0 Sec34-like family Nif11 PF07862.11 ORY01630.1 - 0.53 10.6 0.1 0.53 10.6 0.1 3.0 3 0 0 3 3 3 0 Nif11 domain NPV_P10 PF05531.12 ORY01630.1 - 0.6 10.6 4.8 3.7 8.1 0.2 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Phage_GPO PF05929.11 ORY01630.1 - 0.61 9.7 11.3 0.026 14.2 1.8 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Occludin_ELL PF07303.13 ORY01630.1 - 0.67 10.7 12.5 3.4 8.5 0.1 3.7 2 1 4 6 6 5 0 Occludin homology domain ORF6C PF10552.9 ORY01630.1 - 0.85 9.7 7.0 2.5 8.2 1.9 2.7 2 0 0 2 2 2 0 ORF6C domain Fzo_mitofusin PF04799.13 ORY01630.1 - 0.9 9.1 5.4 0.68 9.5 1.0 2.7 3 0 0 3 3 3 0 fzo-like conserved region RhoGEF PF00621.20 ORY01630.1 - 1.2 9.3 14.1 0.38 11.0 9.6 2.4 2 1 1 3 3 3 0 RhoGEF domain XhlA PF10779.9 ORY01630.1 - 1.9 8.8 6.3 7.3 6.9 0.3 2.8 2 0 0 2 2 2 0 Haemolysin XhlA P4Ha_N PF08336.11 ORY01630.1 - 1.9 8.5 10.2 1.5 8.8 0.5 3.3 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PHM7_cyt PF14703.6 ORY01630.1 - 6.3 7.0 10.8 0.34 11.1 3.1 2.2 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter APG6_N PF17675.1 ORY01630.1 - 7.5 7.1 22.1 0.097 13.2 5.1 3.0 1 1 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_S21e PF01249.18 ORY01631.1 - 3.2e-40 136.1 0.0 3.6e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4325 PF14213.6 ORY01631.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) PAT1 PF09770.9 ORY01632.1 - 3.5e-132 442.5 17.8 2.9e-114 383.2 6.5 3.0 2 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 ATP_Ca_trans_C PF12424.8 ORY01632.1 - 0.2 12.1 2.5 0.22 12.0 0.7 2.0 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal COX7C PF02935.16 ORY01633.1 - 2.1e-17 63.1 0.3 2.2e-17 63.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Bot1p PF12298.8 ORY01634.1 - 1.8e-30 106.4 1.8 1.8e-30 106.4 1.8 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-S22 PF10245.9 ORY01634.1 - 1.3e-11 44.7 0.8 2.5e-11 43.8 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 MRP-L20 PF12824.7 ORY01634.1 - 0.021 15.0 0.0 0.021 15.0 0.0 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.11 ORY01634.1 - 0.031 14.3 0.0 0.031 14.3 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0240) HSF_DNA-bind PF00447.17 ORY01635.1 - 7.5e-23 81.0 0.1 1.2e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Oxidored_molyb PF00174.19 ORY01636.1 - 1.6e-54 184.1 0.0 2.7e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY01636.1 - 9.7e-42 142.3 0.1 2e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 ORY01636.1 - 6e-35 119.6 0.0 1.2e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY01636.1 - 3.8e-30 104.7 0.0 9.4e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORY01636.1 - 1.6e-23 82.6 0.0 3.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORY01636.1 - 4e-07 30.3 0.0 7.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORY01636.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ribosom_S12_S23 PF00164.25 ORY01637.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RIBIOP_C PF04950.12 ORY01638.1 - 1.2e-98 330.1 0.0 1.2e-98 330.1 0.0 2.8 3 0 0 3 3 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY01638.1 - 1.5e-32 111.6 0.3 5.7e-32 109.7 0.0 2.3 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 ORY01638.1 - 6.5e-07 29.1 0.0 0.00047 19.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY01638.1 - 5.8e-06 26.6 0.0 2.1e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY01638.1 - 2.3e-05 24.6 1.1 5.1e-05 23.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 ORY01638.1 - 8.7e-05 23.0 0.2 0.00044 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 ORY01638.1 - 0.00023 20.9 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 ORY01638.1 - 0.00027 21.4 0.1 0.0006 20.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY01638.1 - 0.00036 21.0 1.6 0.00092 19.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 ORY01638.1 - 0.0005 20.1 0.3 0.0044 17.1 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY01638.1 - 0.0013 19.3 0.2 0.009 16.6 0.0 2.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 ORY01638.1 - 0.0065 16.8 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 ORY01638.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY01638.1 - 0.0072 15.6 1.7 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 ORY01638.1 - 0.0073 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ploopntkinase3 PF18751.1 ORY01638.1 - 0.0096 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 cobW PF02492.19 ORY01638.1 - 0.0098 15.5 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORY01638.1 - 0.012 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 ORY01638.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 ORY01638.1 - 0.016 15.0 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 ORY01638.1 - 0.023 15.1 0.1 0.023 15.1 0.1 3.6 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 ORY01638.1 - 0.034 14.1 0.2 0.07 13.0 0.2 1.5 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 ORY01638.1 - 0.038 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 ORY01638.1 - 0.04 14.2 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ORY01638.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 ORY01638.1 - 0.06 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 ORY01638.1 - 0.087 12.9 0.0 0.43 10.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY01638.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ORY01638.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 ORY01638.1 - 0.15 11.1 0.0 0.47 9.4 0.0 1.8 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORY01638.1 - 0.68 10.0 4.6 0.78 9.8 0.1 3.1 3 0 0 3 3 3 0 Dynamin family RRM_1 PF00076.22 ORY01639.1 - 3.2e-19 68.5 0.0 4.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 ORY01639.1 - 3.1e-07 30.2 3.7 5.8e-07 29.3 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY01639.1 - 3.2e-05 23.6 3.2 7.7e-05 22.3 3.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ORY01639.1 - 0.00071 19.4 1.8 0.0011 18.7 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 ORY01639.1 - 0.0031 17.4 1.5 0.0072 16.3 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 ORY01639.1 - 0.039 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Plasmodium_Vir PF05795.11 ORY01639.1 - 3.3 7.0 6.7 0.3 10.4 0.9 1.8 1 1 1 2 2 2 0 Plasmodium vivax Vir protein tRNA-synt_2 PF00152.20 ORY01640.1 - 7.3e-76 255.2 0.7 1e-75 254.8 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY01640.1 - 3.4e-05 23.8 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY01640.1 - 0.028 13.9 0.5 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) CdiA_C PF18451.1 ORY01640.1 - 0.22 11.8 1.1 1.9 8.8 0.6 2.5 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Colicin PF01024.19 ORY01640.1 - 1.5 8.7 5.4 8.7 6.2 0.1 2.2 2 0 0 2 2 2 0 Colicin pore forming domain CTP_transf_1 PF01148.20 ORY01641.1 - 1.4e-84 284.0 20.6 1.8e-84 283.7 20.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family RNA_pol_A_CTD PF03118.15 ORY01642.1 - 0.087 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORY01643.1 - 0.089 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORY01644.1 - 0.086 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORY01645.1 - 0.097 12.4 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORY01646.1 - 0.23 11.2 0.0 2.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORY01647.1 - 0.086 12.6 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_CTD PF03118.15 ORY01648.1 - 0.098 12.4 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain UNC-93 PF05978.16 ORY01649.1 - 8e-05 22.4 9.3 8e-05 22.4 9.3 3.1 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Polysacc_deac_1 PF01522.21 ORY01650.1 - 6.4e-27 93.9 0.0 9.7e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY01650.1 - 1.1e-11 44.9 52.1 6e-08 33.0 17.5 2.9 3 0 0 3 3 3 2 Chitin recognition protein DUF2334 PF10096.9 ORY01650.1 - 0.051 13.2 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Herpes_capsid PF06112.11 ORY01650.1 - 5.1 7.1 6.2 9.2 6.3 6.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein dCMP_cyt_deam_1 PF00383.23 ORY01690.1 - 6e-12 45.3 0.1 8.2e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY01690.1 - 2.8e-08 33.6 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 ORY01690.1 - 0.0041 17.2 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase SNAD4 PF18750.1 ORY01690.1 - 0.0041 17.2 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 ORY01690.1 - 0.0042 17.2 0.6 0.0073 16.4 0.1 1.6 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC2 PF18772.1 ORY01690.1 - 0.0083 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 ORY01690.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 ORY01690.1 - 0.037 14.1 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 ORY01690.1 - 0.062 13.4 0.0 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 ORY01690.1 - 0.069 13.3 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 Inv-AAD PF18785.1 ORY01690.1 - 0.12 12.2 1.0 0.32 10.8 1.0 1.8 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase DUF1450 PF07293.11 ORY01690.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) Myb_DNA-bind_4 PF13837.6 ORY01695.1 - 3.1e-19 69.1 1.1 3.1e-19 69.1 1.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY01695.1 - 5.4e-08 33.0 1.4 5.4e-08 33.0 1.4 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY01695.1 - 9.1e-08 32.2 0.5 3.3e-07 30.4 0.6 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY01695.1 - 0.0003 21.0 0.5 0.0003 21.0 0.5 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORY01695.1 - 0.068 14.2 0.9 0.068 14.2 0.9 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cob_adeno_trans PF01923.18 ORY01696.1 - 2.9e-56 190.1 0.0 3.5e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Uso1_p115_head PF04869.14 ORY01697.1 - 3.1e-74 249.9 1.5 1.4e-73 247.8 0.0 2.8 3 1 1 4 4 4 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 ORY01697.1 - 1.5e-07 31.2 1.1 3.9e-07 29.9 0.3 2.2 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor RTP1_C1 PF10363.9 ORY01697.1 - 1.7e-05 25.0 0.3 0.37 11.0 0.0 3.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Uso1_p115_C PF04871.13 ORY01697.1 - 3.9e-05 24.0 14.0 7.9e-05 23.0 14.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tup_N PF08581.10 ORY01697.1 - 5.3e-05 23.4 5.6 5.3e-05 23.4 5.6 2.4 1 1 1 2 2 2 1 Tup N-terminal Atx10homo_assoc PF09759.9 ORY01697.1 - 0.00022 21.2 1.1 0.18 11.8 0.0 3.9 3 1 0 3 3 2 1 Spinocerebellar ataxia type 10 protein domain HMMR_N PF15905.5 ORY01697.1 - 0.00076 19.1 9.5 0.0012 18.4 9.5 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 ORY01697.1 - 0.0016 18.7 10.5 0.0016 18.7 10.5 1.9 2 1 0 2 2 1 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 ORY01697.1 - 0.0035 17.1 12.9 0.016 15.0 5.7 2.4 1 1 1 2 2 2 2 Phage minor structural protein GP20 Leu_zip PF15294.6 ORY01697.1 - 0.0048 16.4 5.4 0.0092 15.5 5.4 1.4 1 0 0 1 1 1 1 Leucine zipper Cnd1 PF12717.7 ORY01697.1 - 0.0049 16.9 0.6 0.13 12.3 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TACC_C PF05010.14 ORY01697.1 - 0.019 14.8 6.7 0.034 13.9 6.7 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3361 PF11841.8 ORY01697.1 - 0.022 14.7 1.1 2 8.3 0.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) NYD-SP28 PF14772.6 ORY01697.1 - 0.063 13.3 6.7 0.14 12.2 6.7 1.5 1 0 0 1 1 1 0 Sperm tail Cnn_1N PF07989.11 ORY01697.1 - 0.1 12.8 6.8 0.31 11.2 6.8 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ABC_tran_CTD PF16326.5 ORY01697.1 - 0.12 12.7 7.1 0.39 11.0 7.1 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 ORY01697.1 - 0.13 12.4 9.9 0.26 11.3 9.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 ORY01697.1 - 0.15 12.4 6.5 0.37 11.1 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DNA_photolyase PF00875.18 ORY01697.1 - 0.19 11.8 0.3 0.82 9.7 0.1 2.1 2 0 0 2 2 2 0 DNA photolyase Spc7 PF08317.11 ORY01697.1 - 0.35 9.7 11.7 0.95 8.3 10.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1840 PF08895.11 ORY01697.1 - 0.49 10.7 0.0 0.49 10.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Fib_alpha PF08702.10 ORY01697.1 - 0.63 10.2 7.2 0.6 10.3 2.4 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 ORY01697.1 - 2.5 8.5 9.0 9.5 6.6 9.0 2.1 1 0 0 1 1 1 0 Csm1 N-terminal domain YjbH PF06082.11 ORY01697.1 - 2.6 6.8 5.0 4.1 6.1 5.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF16 PF01519.16 ORY01697.1 - 2.9 8.4 9.6 1.5 9.3 6.1 2.3 2 1 0 2 2 1 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.22 ORY01697.1 - 3.7 7.8 8.4 20 5.4 8.4 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 ORY01697.1 - 4.1 7.8 9.3 0.87 9.9 3.6 3.0 2 1 1 3 3 2 0 TSC-22/dip/bun family Angiomotin_C PF12240.8 ORY01699.1 - 0.021 14.4 0.3 0.021 14.4 0.3 1.5 2 0 0 2 2 2 0 Angiomotin C terminal Radical_SAM PF04055.21 ORY01699.1 - 0.056 13.8 3.6 14 6.0 3.6 2.1 1 1 0 1 1 1 0 Radical SAM superfamily Adaptin_binding PF10199.9 ORY01699.1 - 0.14 12.8 1.3 0.19 12.3 1.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PyrI_C PF02748.15 ORY01699.1 - 1.1 9.2 8.0 2.7 8.0 0.0 2.8 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Pkinase PF00069.25 ORY01700.1 - 4.2e-67 226.3 0.0 4.9e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01700.1 - 2.1e-24 86.2 0.0 3e-24 85.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY01700.1 - 0.00052 19.4 0.0 0.0027 17.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORY01700.1 - 0.0085 16.0 0.2 0.033 14.1 0.1 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 ORY01700.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 ORY01700.1 - 0.052 13.1 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 ORY01700.1 - 0.061 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY01700.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 OST3_OST6 PF04756.13 ORY01701.1 - 3.1e-85 286.1 0.0 3.7e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glucos_trans_II PF14264.6 ORY01701.1 - 0.24 10.7 11.6 0.03 13.7 7.6 1.5 2 0 0 2 2 2 0 Glucosyl transferase GtrII DUF5090 PF17009.5 ORY01701.1 - 8.7 6.2 8.3 7.6 6.4 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) RabGAP-TBC PF00566.18 ORY01702.1 - 3.2e-41 141.3 0.2 4.9e-41 140.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.22 ORY01703.1 - 1.4e-59 200.3 0.0 1.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY01703.1 - 7e-36 123.1 0.0 1.2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY01703.1 - 9.3e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY01703.1 - 5.2e-06 26.5 0.0 8.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY01703.1 - 9.3e-06 25.2 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY01703.1 - 1.5e-05 25.0 0.2 0.19 11.6 0.1 2.3 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORY01703.1 - 0.00027 20.6 0.0 0.0008 19.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORY01703.1 - 0.015 15.7 0.1 0.03 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 ORY01703.1 - 0.16 11.4 0.0 0.35 10.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 ORY01703.1 - 0.18 11.2 0.0 14 4.9 0.0 2.1 2 0 0 2 2 2 0 KaiC Actin PF00022.19 ORY01704.1 - 1.6e-151 504.6 0.0 1.8e-151 504.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY01704.1 - 0.011 14.5 0.0 0.026 13.3 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein HRDC PF00570.23 ORY01704.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 HRDC domain HECT PF00632.25 ORY01705.1 - 5.9e-92 308.4 0.2 8e-92 308.0 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MACPF PF01823.19 ORY01706.1 - 1.7e-20 74.0 0.9 1.7e-20 74.0 0.9 1.7 1 1 0 2 2 2 1 MAC/Perforin domain Thiol_cytolysin PF01289.19 ORY01706.1 - 0.013 14.5 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin FAD_binding_3 PF01494.19 ORY01707.1 - 2.5e-26 92.8 0.0 5.4e-15 55.5 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY01707.1 - 1.7e-05 24.5 0.0 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY01707.1 - 2.2e-05 23.8 0.0 0.0006 19.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY01707.1 - 5.5e-05 22.3 0.0 0.00045 19.4 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY01707.1 - 0.00024 21.3 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ORY01707.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ORY01707.1 - 0.0034 17.9 0.0 0.03 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY01707.1 - 0.0046 16.1 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 ORY01707.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 ORY01707.1 - 0.06 12.0 0.0 0.36 9.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ORY01707.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY01707.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY01707.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mak10 PF04112.13 ORY01708.1 - 1.7e-53 180.6 0.1 3.1e-53 179.7 0.1 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase HSF_DNA-bind PF00447.17 ORY01709.1 - 4.1e-34 117.1 0.9 4.1e-34 117.1 0.9 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 ORY01709.1 - 0.084 13.3 0.3 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Ets-domain Tfb4 PF03850.14 ORY01709.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 HA2 PF04408.23 ORY01710.1 - 4.6e-18 65.5 0.0 1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY01710.1 - 4.8e-14 52.6 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY01710.1 - 3.8e-08 33.3 0.0 7.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY01710.1 - 2.4e-06 28.0 0.1 5.2e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY01710.1 - 0.00032 19.8 0.0 0.00067 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 ORY01710.1 - 0.014 14.7 0.9 0.056 12.8 0.1 2.1 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 ORY01710.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY01710.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY01710.1 - 0.019 14.8 0.2 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY01710.1 - 1.6 9.0 3.2 11 6.3 3.2 2.1 1 1 0 1 1 1 0 AAA domain Aminotran_4 PF01063.19 ORY01711.1 - 3.4e-32 112.1 0.0 4.4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Striatin PF08232.12 ORY01712.1 - 3.3e-46 157.7 0.3 3.3e-46 157.7 0.3 2.9 2 1 1 3 3 3 1 Striatin family WD40 PF00400.32 ORY01712.1 - 4.4e-33 112.8 21.1 4.3e-06 27.4 1.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY01712.1 - 7.2e-12 45.4 0.2 0.58 10.5 0.0 5.8 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY01712.1 - 0.0094 14.7 1.4 0.13 11.0 0.1 2.9 2 1 0 2 2 2 1 Nup133 N terminal like Snf7 PF03357.21 ORY01712.1 - 0.064 12.8 5.0 0.14 11.8 5.0 1.4 1 0 0 1 1 1 0 Snf7 Ge1_WD40 PF16529.5 ORY01712.1 - 0.094 11.7 0.1 38 3.1 0.1 3.4 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4482 PF14818.6 ORY01712.1 - 0.68 10.8 8.6 0.21 12.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) DRIM PF07539.12 ORY01713.1 - 1.4e-193 644.7 3.2 1.4e-193 644.7 3.2 5.2 5 1 2 7 7 7 2 Down-regulated in metastasis Dopey_N PF04118.14 ORY01713.1 - 0.56 9.3 6.5 1.1 8.3 0.0 3.9 4 0 0 4 4 4 0 Dopey, N-terminal Y_phosphatase PF00102.27 ORY01714.1 - 9.3e-07 28.6 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY01714.1 - 3.2e-06 27.0 0.0 5.3e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORY01714.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PRMT5_TIM PF17285.2 ORY01714.1 - 0.055 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 PRMT5 TIM barrel domain Complex1_LYR_2 PF13233.6 ORY01715.1 - 1.3e-14 54.6 2.5 1.7e-14 54.3 2.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Taxilin PF09728.9 ORY01715.1 - 0.0013 17.9 1.6 0.0015 17.8 1.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein FF PF01846.19 ORY01715.1 - 0.011 15.8 0.9 0.084 13.1 0.1 2.2 2 0 0 2 2 2 0 FF domain EnY2 PF10163.9 ORY01715.1 - 0.11 12.9 1.4 0.18 12.2 1.4 1.5 1 1 0 1 1 1 0 Transcription factor e(y)2 PUF PF00806.19 ORY01716.1 - 4.2e-62 202.5 15.6 3.2e-09 36.0 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 ORY01716.1 - 3.2e-08 33.3 3.2 1e-07 31.7 3.2 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY01716.1 - 9.2e-08 31.9 5.7 2.8e-07 30.4 5.7 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 ORY01716.1 - 2.4e-06 27.2 3.5 2.4e-06 27.2 3.5 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 ORY01716.1 - 0.00045 20.9 0.4 0.0013 19.5 0.0 1.9 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 ORY01716.1 - 0.00065 20.1 2.4 0.0022 18.4 2.4 2.0 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger PriX PF18689.1 ORY01716.1 - 0.12 12.7 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Primase X TylF PF05711.11 ORY01716.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) LOB PF03195.14 ORY01716.1 - 1.3 9.7 3.9 15 6.3 0.0 4.0 2 1 1 4 4 4 0 Lateral organ boundaries (LOB) domain Chitin_bind_1 PF00187.19 ORY01718.1 - 2.5e-08 34.3 17.0 6.4e-08 32.9 16.9 1.7 1 1 0 1 1 1 1 Chitin recognition protein Plasmodium_Vir PF05795.11 ORY01718.1 - 2.5 7.4 4.7 3.7 6.9 4.7 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein VPS9 PF02204.18 ORY01719.1 - 5.8e-30 103.6 0.7 1.3e-29 102.5 0.7 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ORY01719.1 - 1.2e-12 48.0 0.0 4.2e-12 46.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 ORY01719.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 CUE domain Atg8 PF02991.16 ORY01720.1 - 6.2e-52 174.1 0.2 7.3e-52 173.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORY01720.1 - 5.7e-06 26.6 0.0 7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.25 ORY01721.1 - 2.7e-74 249.9 0.0 3.3e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01721.1 - 1.2e-50 172.2 0.0 1.6e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY01721.1 - 7e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY01721.1 - 0.00021 20.7 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY01721.1 - 0.0013 17.7 0.1 0.93 8.4 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain AAA PF00004.29 ORY01754.1 - 9.6e-15 55.2 0.0 3.8e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY01754.1 - 1.3e-14 54.7 0.0 3.8e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 ORY01754.1 - 1.3e-12 47.5 0.1 3e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 ORY01754.1 - 4.3e-12 46.7 0.1 5.2e-10 40.0 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 ORY01754.1 - 2.6e-07 30.3 0.0 5.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 ORY01754.1 - 2.7e-06 27.4 0.1 8.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_lid_10 PF17872.1 ORY01754.1 - 2.4e-05 24.4 0.3 5.8e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_14 PF13173.6 ORY01754.1 - 0.0014 18.6 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORY01754.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORY01754.1 - 0.0032 17.8 0.0 0.021 15.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 ORY01754.1 - 0.005 16.4 0.5 0.027 14.1 0.1 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 ORY01754.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 ORY01754.1 - 0.011 16.2 1.7 0.58 10.7 0.0 3.0 3 1 1 4 4 3 0 ABC transporter DUF815 PF05673.13 ORY01754.1 - 0.011 14.9 0.0 0.034 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 ORY01754.1 - 0.013 15.5 0.0 0.032 14.1 0.0 1.7 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 ORY01754.1 - 0.015 14.6 0.0 0.072 12.4 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_30 PF13604.6 ORY01754.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY01754.1 - 0.018 14.5 0.0 0.061 12.8 0.0 1.9 2 1 1 3 3 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 ORY01754.1 - 0.018 14.8 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 ORY01754.1 - 0.022 14.7 0.6 0.44 10.4 0.1 2.8 2 1 0 2 2 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ORY01754.1 - 0.024 14.6 0.1 0.59 10.0 0.0 2.6 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 ORY01754.1 - 0.033 13.4 0.1 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain BET PF17035.5 ORY01754.1 - 0.034 14.3 1.7 2.9 8.1 0.2 2.6 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation PIF1 PF05970.14 ORY01754.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_28 PF13521.6 ORY01754.1 - 0.043 14.1 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY01754.1 - 0.057 13.8 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 ORY01754.1 - 0.062 13.3 0.1 0.42 10.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 ORY01754.1 - 0.073 13.1 0.1 4.1 7.4 0.0 2.7 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY01754.1 - 0.083 12.3 0.1 0.24 10.8 0.0 1.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 ORY01754.1 - 0.17 12.1 0.0 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Homeodomain PF00046.29 ORY01755.1 - 2.5e-20 72.1 1.5 4.5e-20 71.2 1.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY01755.1 - 0.032 14.2 1.2 0.084 12.8 0.3 2.1 2 0 0 2 2 2 0 Homeobox KN domain Peptidase_M49 PF03571.15 ORY01756.1 - 5.4e-09 35.0 3.3 3.9e-08 32.1 0.8 2.9 2 2 1 3 3 3 2 Peptidase family M49 TIP120 PF08623.10 ORY01756.1 - 0.02 14.7 0.0 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) C2 PF00168.30 ORY01757.1 - 1.9e-16 60.2 0.1 2.4e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 C2 domain PEMT PF04191.13 ORY01758.1 - 3.6e-55 184.9 9.1 8.1e-33 113.0 1.3 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 ORY01758.1 - 0.00062 20.3 0.0 0.0021 18.6 0.0 1.9 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 ORY01758.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Tetraspanin PF00335.20 ORY01758.1 - 0.0051 16.5 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 Tetraspanin family GP24_25 PF17388.2 ORY01758.1 - 0.062 13.3 0.6 0.12 12.4 0.6 1.4 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 DUF520 PF04461.13 ORY01758.1 - 0.083 13.0 0.6 0.39 10.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF520) MCPsignal PF00015.21 ORY01758.1 - 0.54 10.1 4.2 0.86 9.4 4.2 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Eaf7 PF07904.13 ORY01759.1 - 8.7e-17 61.4 0.1 2e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Stm1_N PF09598.10 ORY01759.1 - 2 9.3 6.7 4.6 8.2 6.7 1.8 1 1 0 1 1 1 0 Stm1 eIF_4EBP PF05456.11 ORY01760.1 - 1.7e-31 108.5 7.7 2.9e-31 107.8 7.7 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) WW PF00397.26 ORY01761.1 - 2.7e-11 43.3 0.7 6.3e-11 42.2 0.7 1.7 1 0 0 1 1 1 1 WW domain Peptidase_C48 PF02902.19 ORY01762.1 - 1.2e-18 67.8 2.1 1.4e-18 67.5 2.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AMP-binding PF00501.28 ORY01764.1 - 1.5e-89 300.5 0.0 1.8e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY01764.1 - 4.1e-22 78.9 0.5 7.9e-22 78.0 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UvrA_DNA-bind PF17755.1 ORY01764.1 - 0.077 13.3 0.1 20 5.6 0.0 2.7 3 0 0 3 3 3 0 UvrA DNA-binding domain Polysacc_deac_1 PF01522.21 ORY01765.1 - 1.5e-32 112.1 0.0 2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase VP9 PF09625.10 ORY01765.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 VP9 protein Polysacc_deac_1 PF01522.21 ORY01767.1 - 2.5e-32 111.4 0.0 4.9e-32 110.4 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase VP9 PF09625.10 ORY01767.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 VP9 protein Polysacc_deac_1 PF01522.21 ORY01768.1 - 1.5e-33 115.3 0.0 2e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY01768.1 - 0.0026 17.0 0.0 0.0032 16.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 nec1 PF10379.9 ORY01768.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Virulence protein nec1 Polysacc_deac_1 PF01522.21 ORY01769.1 - 8.7e-33 112.9 0.0 1.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY01769.1 - 9.5e-05 21.7 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORY01769.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) zf-RAG1 PF10426.9 ORY01769.1 - 0.27 11.4 1.6 4.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain HlyIII PF03006.20 ORY01770.1 - 1.7e-46 158.7 18.8 3e-46 157.9 18.8 1.4 1 1 0 1 1 1 1 Haemolysin-III related Solute_trans_a PF03619.16 ORY01771.1 - 8e-40 137.0 18.2 9.9e-40 136.7 18.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MORN PF02493.20 ORY01771.1 - 0.15 12.0 0.5 0.44 10.5 0.5 1.8 1 0 0 1 1 1 0 MORN repeat Chitin_bind_1 PF00187.19 ORY01773.1 - 5.3e-07 30.0 15.4 1.1e-06 29.0 15.4 1.5 1 0 0 1 1 1 1 Chitin recognition protein Sporozoite_P67 PF05642.11 ORY01773.1 - 0.62 8.1 14.5 0.73 7.8 14.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AMP-binding PF00501.28 ORY01774.1 - 1.4e-90 303.9 0.0 1.7e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY01774.1 - 1.5e-12 48.3 0.5 3.9e-12 47.0 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 ORY01775.1 - 5.8e-35 120.9 52.5 5.3e-30 104.5 32.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01775.1 - 2.8e-09 36.4 17.9 2.9e-06 26.4 1.6 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ORY01775.1 - 0.00067 18.3 14.5 0.016 13.8 5.0 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORY01775.1 - 0.00097 18.1 1.7 0.00097 18.1 1.7 2.8 1 1 0 2 2 2 2 MFS_1 like family Antimicrobial24 PF16049.5 ORY01775.1 - 2.3 8.2 5.9 0.26 11.3 0.3 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide PHD PF00628.29 ORY01776.1 - 0.00013 21.8 14.6 0.00013 21.8 14.6 4.1 4 0 0 4 4 4 1 PHD-finger EF-hand_like PF09279.11 ORY01776.1 - 0.026 15.0 0.6 0.11 13.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like GCP_N_terminal PF17681.1 ORY01777.1 - 6.2e-62 210.0 1.3 1.2e-61 209.0 0.1 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY01777.1 - 9.9e-54 182.9 2.8 1.9e-53 181.9 2.8 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Semialdhyde_dhC PF02774.18 ORY01779.1 - 7.4e-40 137.0 0.0 1.1e-39 136.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ORY01779.1 - 1.8e-30 105.9 0.0 3.2e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 ORY01779.1 - 0.00087 20.0 1.3 0.012 16.3 0.0 3.1 3 1 0 3 3 3 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 ORY01779.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 ORY01779.1 - 0.094 13.0 0.1 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORY01779.1 - 0.17 11.7 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Arrestin_C PF02752.22 ORY01780.1 - 2.2e-11 44.4 0.0 1.7e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY01780.1 - 2.5e-05 24.4 0.1 0.00039 20.5 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SAP30_Sin3_bdg PF13867.6 ORY01781.1 - 2.4e-17 63.0 0.6 4e-17 62.3 0.6 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Type_III_YscX PF09474.10 ORY01781.1 - 0.03 14.6 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Evr1_Alr PF04777.13 ORY01781.1 - 0.073 13.5 0.2 0.1 13.1 0.1 1.3 1 1 0 1 1 1 0 Erv1 / Alr family DUF4661 PF15576.6 ORY01781.1 - 0.11 12.4 1.1 0.12 12.3 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Piwi PF02171.17 ORY01783.1 - 3e-104 348.5 0.0 4.3e-104 348.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORY01783.1 - 1.5e-25 90.4 0.0 3.1e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 ORY01783.1 - 1.4e-19 69.5 0.1 3e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ORY01783.1 - 1.5e-16 60.4 0.1 3.7e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 ORY01783.1 - 1.1e-15 57.7 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 ORY01783.1 - 2.4e-13 50.2 0.0 8e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute HBD PF18534.1 ORY01783.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Helical bundle domain Cupin_2 PF07883.11 ORY01784.1 - 8.6e-16 57.4 0.0 1.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 ORY01784.1 - 1.4e-06 28.3 0.0 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 ORY01784.1 - 0.00019 21.5 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 ORY01784.1 - 0.0077 16.1 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ORY01784.1 - 0.014 15.0 0.0 0.082 12.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Lyx_isomer PF07385.12 ORY01784.1 - 0.041 13.1 0.0 0.57 9.4 0.0 1.9 1 1 1 2 2 2 0 D-lyxose isomerase FAM101 PF15068.6 ORY01784.1 - 0.058 13.3 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 FAM101 family zf-C3HC4_3 PF13920.6 ORY01785.1 - 0.00018 21.3 10.2 0.00039 20.2 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY01785.1 - 8.6 6.3 13.0 19 5.2 13.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_9 PF13527.7 ORY01786.1 - 1e-20 74.1 0.0 2.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY01786.1 - 2.4e-07 31.0 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY01786.1 - 4.4e-07 29.9 0.0 9.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY01786.1 - 2.9e-06 27.6 0.0 6.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY01786.1 - 1.4e-05 25.0 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 ORY01786.1 - 0.029 14.3 0.0 0.8 9.7 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase E1-E2_ATPase PF00122.20 ORY01787.1 - 2e-43 148.0 3.2 1.1e-41 142.4 0.7 2.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 ORY01787.1 - 6.5e-22 77.0 2.2 6.6e-22 77.0 0.2 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus ABC2_membrane_2 PF12679.7 ORY01787.1 - 0.017 14.5 0.4 0.024 14.0 0.4 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF1772 PF08592.11 ORY01787.1 - 0.052 13.9 0.0 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Cation_ATPase_C PF00689.21 ORY01788.1 - 8.6e-48 162.5 8.5 2.2e-47 161.2 8.8 1.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY01788.1 - 5.8e-22 79.0 0.5 1.7e-20 74.3 0.5 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY01788.1 - 3.5e-19 68.7 0.1 6.4e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY01788.1 - 4e-08 33.3 3.0 2.1e-06 27.7 1.6 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY01788.1 - 1.8e-05 25.2 0.0 4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L14e PF01929.17 ORY01791.1 - 3.6e-32 110.7 1.9 5.1e-32 110.2 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORY01791.1 - 0.00061 19.6 0.5 0.0013 18.6 0.5 1.6 1 0 0 1 1 1 1 KOW motif Peptidase_M90 PF06167.12 ORY01793.1 - 7.8e-06 25.7 0.2 6.3e-05 22.7 0.2 2.1 1 1 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 ShK PF01549.24 ORY01793.1 - 0.001 19.5 6.6 0.001 19.5 6.6 2.3 2 0 0 2 2 2 1 ShK domain-like Catalase PF00199.19 ORY01794.1 - 2e-203 675.6 0.6 2.5e-203 675.3 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY01794.1 - 9e-24 83.5 0.1 2.7e-23 82.0 0.1 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Peripla_BP_2 PF01497.18 ORY01795.1 - 4.1e-08 33.1 0.0 1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein DUF2312 PF10073.9 ORY01795.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Catalase PF00199.19 ORY01796.1 - 2e-203 675.6 0.6 2.5e-203 675.3 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY01796.1 - 9e-24 83.5 0.1 2.7e-23 82.0 0.1 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase PF00199.19 ORY01797.1 - 2e-203 675.6 0.6 2.5e-203 675.3 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY01797.1 - 9e-24 83.5 0.1 2.7e-23 82.0 0.1 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 ORY01798.1 - 8.7e-51 172.9 49.9 1e-48 166.1 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY01798.1 - 2.7e-15 56.2 29.9 3.1e-15 56.0 8.9 3.7 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_4 PF06779.14 ORY01798.1 - 1.1e-05 24.9 1.7 1.1e-05 24.9 1.7 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF1269 PF06897.12 ORY01798.1 - 1.2 9.5 3.5 2.8 8.3 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) OATP PF03137.20 ORY01798.1 - 7.7 4.7 14.6 1.1 7.4 3.2 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family NUC173 PF08161.12 ORY01799.1 - 9.6e-63 211.5 0.5 6.6e-57 192.5 0.0 4.0 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.22 ORY01799.1 - 0.0088 16.2 0.1 4.2 7.9 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat RP-C_C PF11800.8 ORY01799.1 - 0.015 15.4 2.1 0.039 14.0 2.1 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region HrpB1_HrpK PF09613.10 ORY01799.1 - 0.016 14.8 0.0 6.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DNA_pol_phi PF04931.13 ORY01799.1 - 0.024 12.7 12.9 0.0039 15.4 4.9 2.9 2 1 1 3 3 3 0 DNA polymerase phi CdiI_2 PF18593.1 ORY01799.1 - 0.16 12.6 1.0 5.8 7.7 0.1 3.5 2 1 1 3 3 3 0 CdiI immunity protein CDC45 PF02724.14 ORY01799.1 - 1.2 7.3 13.7 2.1 6.6 13.7 1.3 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 ORY01799.1 - 3.8 7.5 9.4 12 5.9 9.4 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 Myticin-prepro PF10690.9 ORY01841.1 - 0.0037 17.5 0.3 0.0056 16.9 0.3 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Gti1_Pac2 PF09729.9 ORY01842.1 - 9.3e-39 133.4 7.0 8.5e-36 123.7 0.5 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family Sdh_cyt PF01127.22 ORY01843.1 - 1.2e-22 80.2 2.5 1.5e-22 79.9 2.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ubiquitin_5 PF18037.1 ORY01843.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin-like domain Pkinase PF00069.25 ORY01844.1 - 1.4e-52 178.7 0.0 1.9e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01844.1 - 2.4e-17 63.1 0.3 4.3e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 ORY01844.1 - 0.015 14.9 0.3 0.033 13.8 0.3 1.5 1 1 0 1 1 1 0 RIO1 family NTP_transferase PF00483.23 ORY01845.1 - 1.3e-53 182.2 0.0 1.6e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY01845.1 - 2.2e-13 49.3 11.1 5.7e-11 41.7 5.4 3.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY01845.1 - 1.1e-10 42.1 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY01845.1 - 0.003 17.3 4.7 0.003 17.3 4.7 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 ORY01845.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 ORY01845.1 - 0.067 11.3 0.2 0.098 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 ORY01845.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase G-alpha PF00503.20 ORY01846.1 - 8.1e-123 410.1 3.0 9.8e-123 409.8 3.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY01846.1 - 2.5e-15 56.4 1.0 2.6e-10 40.0 0.4 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORY01846.1 - 0.00013 21.7 0.1 0.00047 19.9 0.1 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORY01846.1 - 0.00058 19.3 0.2 0.094 12.0 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY01846.1 - 0.0015 18.7 0.2 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY01846.1 - 0.033 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 ORY01846.1 - 0.044 13.3 0.0 1.1 8.7 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY01846.1 - 0.055 13.5 0.1 6.9 6.8 0.0 2.8 1 1 1 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 ORY01846.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 ORY01846.1 - 0.079 12.6 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Ras family FtsK_SpoIIIE PF01580.18 ORY01846.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 ORY01846.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain BAR PF03114.18 ORY01847.1 - 4.4e-32 111.6 0.1 6.2e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY01847.1 - 2.3e-16 59.1 0.1 3.6e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY01847.1 - 4.3e-14 52.1 0.1 6.8e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY01847.1 - 1.7e-12 46.8 0.0 3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 ORY01847.1 - 0.0075 15.9 1.0 0.065 12.8 1.0 2.1 1 1 0 1 1 1 1 Arfaptin-like domain BRE1 PF08647.11 ORY01847.1 - 0.021 14.9 1.4 4.5 7.4 0.3 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase CT_C_D PF02682.16 ORY01847.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D TMEM132 PF16070.5 ORY01848.1 - 0.046 13.1 0.1 0.053 12.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein family 132 TQ PF18202.1 ORY01848.1 - 0.089 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 T-Q ester bond containing domain EIF_2_alpha PF07541.12 ORY01862.1 - 3.5e-45 152.8 0.1 6.2e-45 152.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ORY01862.1 - 1e-12 48.2 0.8 2.2e-12 47.1 0.8 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF4453 PF14627.6 ORY01862.1 - 0.0091 16.1 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4453) Spindle_Spc25 PF08234.12 ORY01862.1 - 0.16 12.2 0.1 8.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 DEAD PF00270.29 ORY01863.1 - 1e-47 162.2 0.0 1.7e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY01863.1 - 3.3e-30 104.7 0.0 4e-29 101.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 ORY01863.1 - 8.7e-26 90.1 0.0 2.1e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 ORY01863.1 - 1.7e-05 24.9 0.0 6e-05 23.1 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY01863.1 - 0.0048 16.2 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 ORY01863.1 - 0.054 12.8 0.0 0.054 12.8 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Polysacc_lyase PF14099.6 ORY01864.1 - 6.8e-05 22.8 0.0 9.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase Polysacc_lyase PF14099.6 ORY01865.1 - 3.9e-05 23.6 0.0 6e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide lyase SAM_decarbox PF01536.16 ORY01866.1 - 4e-107 358.3 0.1 2.1e-98 329.6 0.1 3.8 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase Pyr_redox_2 PF07992.14 ORY01867.1 - 4e-50 170.7 0.1 4.5e-50 170.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY01867.1 - 2.9e-17 62.9 0.3 5.3e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY01867.1 - 1.3e-16 60.9 0.1 2.4e-15 56.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY01867.1 - 0.00014 21.2 0.4 0.00092 18.5 0.2 2.1 2 0 0 2 2 2 1 Thi4 family PolyA_pol PF01743.20 ORY01867.1 - 0.0083 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain FAD_oxidored PF12831.7 ORY01867.1 - 0.01 15.2 0.2 0.059 12.7 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY01867.1 - 0.044 12.8 2.7 0.26 10.3 0.3 3.0 3 1 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY01867.1 - 0.047 12.8 3.0 0.3 10.1 0.9 2.7 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 ORY01867.1 - 0.11 12.8 0.1 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY01867.1 - 0.23 10.6 0.0 3.3 6.7 0.0 2.5 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 ORY01867.1 - 0.27 11.7 0.7 1.2 9.6 0.0 2.2 3 1 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 ORY01867.1 - 2.4 6.8 3.9 1.5 7.4 0.9 2.1 3 0 0 3 3 3 0 HI0933-like protein SIR2 PF02146.17 ORY01868.1 - 1.8e-37 129.0 0.0 3.6e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Sir2 family Vps36-NZF-N PF16988.5 ORY01868.1 - 0.06 12.7 0.2 0.17 11.3 0.2 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_15 PF17032.5 ORY01868.1 - 0.12 13.2 1.7 0.24 12.2 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon family ActA PF05058.12 ORY01868.1 - 0.65 8.3 9.3 1 7.6 9.3 1.2 1 0 0 1 1 1 0 ActA Protein MRP-S33 PF08293.11 ORY01869.1 - 1.9e-27 95.3 0.1 2.2e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gemini_C4 PF01492.17 ORY01869.1 - 0.08 12.9 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Geminivirus C4 protein GST_C_3 PF14497.6 ORY01870.1 - 3.8e-23 81.5 0.1 7.4e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY01870.1 - 2.3e-07 30.9 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY01870.1 - 0.054 13.9 0.1 0.2 12.0 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain NFRKB_winged PF14465.6 ORY01871.1 - 0.1 12.8 3.0 0.092 12.9 1.7 1.6 1 1 0 1 1 1 0 NFRKB Winged Helix-like Band_3_cyto PF07565.13 ORY01872.1 - 0.063 13.1 0.1 0.067 13.0 0.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NFRKB_winged PF14465.6 ORY01872.1 - 0.096 12.9 2.9 0.091 13.0 1.7 1.6 1 1 0 1 1 1 0 NFRKB Winged Helix-like AA_permease_2 PF13520.6 ORY01873.1 - 2.1e-53 181.7 45.7 2.9e-53 181.2 45.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01873.1 - 1.7e-41 142.4 42.4 2.1e-41 142.0 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORY01873.1 - 9e-09 35.3 2.8 9e-09 35.3 2.8 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease NADHdh_A3 PF14987.6 ORY01873.1 - 2 8.8 4.6 0.99 9.8 1.0 2.5 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 AA_permease_2 PF13520.6 ORY01874.1 - 1.1e-08 34.4 16.9 8.6e-07 28.1 11.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 ORY01874.1 - 1.9e-06 26.8 8.0 2.2e-06 26.6 8.0 1.1 1 0 0 1 1 1 1 Amino acid permease PSII_Ycf12 PF05969.11 ORY01874.1 - 0.19 11.7 3.1 0.64 10.1 3.1 1.9 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 HCMV_UL124 PF17609.2 ORY01874.1 - 0.24 11.6 0.5 0.39 10.9 0.3 1.5 1 1 0 1 1 1 0 Family of unknown function DUF983 PF06170.12 ORY01874.1 - 8.3 6.9 11.2 9.7 6.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) AA_permease_2 PF13520.6 ORY01875.1 - 3.9e-55 187.4 53.1 5.2e-55 187.0 53.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01875.1 - 1.3e-34 119.7 46.5 1.6e-34 119.3 46.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORY01875.1 - 2.5e-07 30.7 8.2 2.5e-07 30.7 8.2 3.9 4 0 0 4 4 4 1 C-terminus of AA_permease NADHdh_A3 PF14987.6 ORY01875.1 - 6.1 7.2 5.5 0.78 10.1 0.6 2.0 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 AA_permease_2 PF13520.6 ORY01876.1 - 1.2e-52 179.2 43.6 1.6e-52 178.8 43.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01876.1 - 6.6e-42 143.7 40.5 8.4e-42 143.4 40.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORY01876.1 - 1.2e-08 34.9 2.7 1.2e-08 34.9 2.7 3.4 3 0 0 3 3 3 1 C-terminus of AA_permease AA_permease_2 PF13520.6 ORY01877.1 - 1.4e-60 205.4 45.3 1.7e-60 205.1 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01877.1 - 8.8e-44 149.9 38.4 1.2e-43 149.4 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORY01877.1 - 4.4e-12 45.9 5.8 5.3e-11 42.4 3.3 3.3 2 0 0 2 2 2 1 C-terminus of AA_permease DUF4131 PF13567.6 ORY01877.1 - 2.4 7.8 7.8 22 4.7 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) AA_permease_2 PF13520.6 ORY01878.1 - 2.9e-60 204.3 50.5 3.6e-60 204.0 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY01878.1 - 8.3e-46 156.6 43.9 1.1e-45 156.2 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ORY01878.1 - 4e-10 39.6 4.3 4e-10 39.6 4.3 3.5 3 0 0 3 3 3 1 C-terminus of AA_permease Shisa PF13908.6 ORY01878.1 - 3.2 8.0 4.4 6.7 6.9 0.4 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3472 PF11958.8 ORY01879.1 - 2.1e-14 54.4 0.7 3e-14 53.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORY01879.1 - 1.6e-09 38.1 8.9 3.1e-09 37.2 8.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORY01879.1 - 0.0045 16.9 0.2 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5077) Abhydrolase_1 PF00561.20 ORY01915.1 - 4.3e-26 92.1 0.0 1.6e-25 90.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY01915.1 - 1.8e-14 53.6 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY01915.1 - 7.4e-14 52.9 0.0 8.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY01915.1 - 1.4e-08 34.8 0.0 5.7e-07 29.5 0.0 2.5 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 ORY01915.1 - 2.5e-08 33.0 0.0 3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 ORY01915.1 - 4e-06 27.1 0.0 4.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 ORY01915.1 - 7e-05 22.8 0.0 0.00013 21.9 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 ORY01915.1 - 8.7e-05 22.3 0.0 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ORY01915.1 - 0.00012 21.7 0.1 0.0028 17.2 0.1 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORY01915.1 - 0.0002 21.3 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY01915.1 - 0.00058 18.8 0.0 0.0039 16.1 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF676 PF05057.14 ORY01915.1 - 0.00075 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 ORY01915.1 - 0.002 17.8 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Putative esterase DUF900 PF05990.12 ORY01915.1 - 0.0065 16.0 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase PF07224.11 ORY01915.1 - 0.0079 15.2 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase LIDHydrolase PF10230.9 ORY01915.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 ORY01915.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.13 ORY01915.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.8 ORY01915.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydro_lipase PF04083.16 ORY01915.1 - 0.027 14.1 0.1 0.81 9.3 0.0 2.5 3 0 0 3 3 2 0 Partial alpha/beta-hydrolase lipase region LCAT PF02450.15 ORY01915.1 - 0.03 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PAF-AH_p_II PF03403.13 ORY01915.1 - 0.03 12.8 0.0 3.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II CRAL_TRIO_2 PF13716.6 ORY01915.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3834 PF12916.7 ORY01915.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) VirJ PF06057.11 ORY01915.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) SWIRM PF04433.17 ORY01916.1 - 0.12 12.7 0.3 0.28 11.5 0.2 1.7 2 1 0 2 2 2 0 SWIRM domain DNA_binding_1 PF01035.20 ORY01918.1 - 4.4e-22 78.0 0.0 7.3e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Tmemb_14 PF03647.13 ORY01919.1 - 6.1e-26 91.0 3.7 6.9e-26 90.8 3.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C MerC PF03203.14 ORY01919.1 - 0.032 14.7 0.2 0.092 13.2 0.2 1.7 1 1 0 1 1 1 0 MerC mercury resistance protein Tim17 PF02466.19 ORY01919.1 - 0.041 14.3 1.3 0.36 11.2 0.0 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RSN1_7TM PF02714.15 ORY01920.1 - 4.2e-65 219.8 28.8 5e-65 219.5 28.8 1.0 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY01920.1 - 1.9e-08 34.7 0.0 3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TssO PF17561.2 ORY01920.1 - 0.074 13.2 0.9 0.21 11.7 0.9 1.7 1 0 0 1 1 1 0 Type VI secretion system, TssO PAS_3 PF08447.12 ORY01921.1 - 2.7e-14 53.2 0.0 1.9e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORY01921.1 - 3.2e-10 40.0 0.0 2.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY01921.1 - 2.3e-08 34.2 0.0 0.00027 21.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 ORY01921.1 - 2.8e-05 24.2 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORY01921.1 - 0.0023 18.2 0.0 0.67 10.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 ORY01921.1 - 0.021 15.5 0.0 6.6 7.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold ASCH PF04266.14 ORY01921.1 - 0.12 12.9 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 ASCH domain F-box PF00646.33 ORY01923.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY01923.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like Sugar_tr PF00083.24 ORY01924.1 - 1.1e-88 298.1 20.9 1.4e-88 297.7 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY01924.1 - 5.1e-32 111.2 23.9 5.1e-32 111.2 23.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY01924.1 - 2.7e-05 22.8 16.0 0.0074 14.8 4.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Inhibitor_I9 PF05922.16 ORY01925.1 - 2.4e-07 31.3 0.0 3.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acetyltransf_1 PF00583.25 ORY01927.1 - 1.2e-14 54.6 0.1 1.9e-14 53.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY01927.1 - 1.7e-11 44.1 0.1 2.7e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY01927.1 - 1.8e-10 41.1 0.5 9.8e-10 38.7 0.4 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY01927.1 - 3.1e-07 30.7 0.1 4.9e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY01927.1 - 4.7e-06 26.5 0.0 9.8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY01927.1 - 0.0046 16.7 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY01927.1 - 0.0054 17.4 0.0 0.0086 16.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY01927.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ORY01927.1 - 0.032 14.1 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 ORY01928.1 - 2.2e-73 246.9 0.0 3.3e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY01928.1 - 1.2e-41 142.8 0.0 1.9e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY01928.1 - 2.7e-15 55.9 0.2 5.2e-15 55.0 0.2 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY01928.1 - 4.3e-07 29.5 0.0 7.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY01928.1 - 1.4e-06 27.8 0.1 2.4e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY01928.1 - 5.3e-06 25.6 0.1 1.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY01928.1 - 1e-05 25.2 0.1 0.0003 20.4 0.1 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 ORY01928.1 - 0.0019 18.2 0.1 0.047 13.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family NMO PF03060.15 ORY01929.1 - 1.5e-45 156.0 2.9 3e-42 145.2 2.9 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ORY01929.1 - 1.2e-13 50.9 0.8 1.2e-13 50.9 0.8 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORY01929.1 - 7.7e-13 48.1 0.6 2e-06 27.0 0.0 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORY01929.1 - 0.00064 19.0 3.1 0.0036 16.5 3.1 1.9 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ORY01929.1 - 0.0038 16.6 0.7 0.0069 15.7 0.7 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG MotA_activ PF09114.10 ORY01929.1 - 0.0077 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Transcription factor MotA, activation domain His_biosynth PF00977.21 ORY01929.1 - 0.0085 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 ORY01929.1 - 0.24 10.6 2.4 0.18 11.0 0.4 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Peptidase_S9 PF00326.21 ORY01930.1 - 1.1e-30 106.8 0.0 1.7e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY01930.1 - 1.2e-08 34.5 0.0 2.3e-05 23.8 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 ORY01930.1 - 1.7e-07 31.0 0.5 0.0013 18.7 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 ORY01930.1 - 3.2e-07 30.3 0.4 0.0014 18.3 0.2 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 ORY01930.1 - 0.0035 15.9 0.1 0.0056 15.2 0.1 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Tannase PF07519.11 ORY01930.1 - 0.04 12.8 0.0 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase DLH PF01738.18 ORY01930.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family peroxidase PF00141.23 ORY01932.1 - 2.2e-48 165.0 0.0 3.3e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Aldo_ket_red PF00248.21 ORY01933.1 - 3.2e-49 167.7 0.0 5.2e-47 160.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Semialdhyde_dh PF01118.24 ORY01933.1 - 0.19 12.2 0.1 0.5 10.8 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF2015 PF09435.10 ORY01934.1 - 1.4e-28 98.9 0.0 1.7e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) XkdW PF09636.10 ORY01935.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 XkdW protein FAD_binding_3 PF01494.19 ORY01936.1 - 2.4e-38 132.3 0.0 1.6e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Velvet PF11754.8 ORY01937.1 - 2.4e-33 116.1 0.3 2.8e-33 115.9 0.3 1.0 1 0 0 1 1 1 1 Velvet factor Mgm101p PF06420.12 ORY01938.1 - 9.2e-84 279.1 0.0 1.1e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHASE5 PF17149.4 ORY01938.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins KCH PF16944.5 ORY01939.1 - 6.7e-63 212.8 23.0 4.2e-62 210.2 23.0 1.9 1 1 0 1 1 1 1 Fungal potassium channel Trypsin PF00089.26 ORY01940.1 - 1.4e-45 155.8 0.0 1.8e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY01940.1 - 7.7e-09 36.6 0.0 1.5e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain COX4 PF02936.14 ORY01941.1 - 2.1e-39 134.7 0.1 2.7e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Ribosomal_S16 PF00886.19 ORY01941.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 DUF1138 PF06592.13 ORY01941.1 - 0.14 12.2 1.3 0.73 9.9 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1138) Trypsin PF00089.26 ORY01942.1 - 2.2e-35 122.5 0.0 8.3e-35 120.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY01942.1 - 0.00075 20.4 0.1 0.0015 19.5 0.1 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain EMP24_GP25L PF01105.24 ORY01943.1 - 1.6e-41 142.3 0.1 1.9e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DDE_Tnp_IS240 PF13610.6 ORY01943.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 DDE domain NIF3 PF01784.18 ORY01944.1 - 3.2e-71 239.8 0.0 3.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glyco_transf_22 PF03901.17 ORY01945.1 - 3.2e-40 138.7 26.5 3.9e-40 138.4 26.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2371 PF10177.9 ORY01945.1 - 0.26 11.4 0.4 0.53 10.5 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Hydrolase_6 PF13344.6 ORY01946.1 - 3.4e-26 91.3 0.0 6.5e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY01946.1 - 6.3e-21 74.2 0.0 2.2e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 HAD-hyrolase-like HAD_2 PF13419.6 ORY01946.1 - 0.093 12.8 0.2 0.62 10.1 0.0 2.4 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY01946.1 - 0.14 12.5 0.0 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sad1_UNC PF07738.13 ORY01947.1 - 1.2e-34 119.2 0.2 3.8e-34 117.6 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Polysacc_lyase PF14099.6 ORY01948.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase Laminin_G_3 PF13385.6 ORY01948.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily MIR PF02815.19 ORY01949.1 - 1.2e-09 38.3 5.4 4e-08 33.3 0.0 3.6 3 1 0 3 3 3 2 MIR domain Ins145_P3_rec PF08709.11 ORY01949.1 - 1.8e-05 24.0 0.8 0.17 11.1 0.1 3.0 2 1 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF3824 PF12868.7 ORY01949.1 - 0.00042 21.0 11.3 0.00057 20.6 10.8 1.4 1 1 0 1 1 1 1 Domain of unknwon function (DUF3824) ETRAMP PF09716.10 ORY01949.1 - 0.069 13.2 2.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Rhomboid PF01694.22 ORY01950.1 - 1.2e-31 109.7 10.4 1.2e-31 109.7 10.4 1.8 2 0 0 2 2 2 1 Rhomboid family PTPLA PF04387.14 ORY01950.1 - 0.0035 17.1 1.7 0.026 14.3 1.7 2.1 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA AhpC-TSA_2 PF13911.6 ORY01951.1 - 4.7e-09 36.4 0.1 6.8e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ORY01951.1 - 2.8e-05 24.0 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY01951.1 - 0.0047 16.7 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin PCNA_N PF00705.18 ORY01952.1 - 1.4e-57 192.8 1.6 1.9e-57 192.5 0.5 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORY01952.1 - 7.2e-53 178.2 0.0 1.1e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 ORY01952.1 - 9.8e-09 35.0 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 ORY01952.1 - 1.9e-06 27.1 0.1 1.5e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Nucleoporin_N PF08801.11 ORY01953.1 - 3.1e-77 260.2 0.1 4.9e-77 259.5 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORY01953.1 - 2e-34 119.3 8.5 5.2e-33 114.6 8.5 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Thiamine_BP PF01910.17 ORY01954.1 - 1.7e-32 111.2 0.0 1.9e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein AP_endonuc_2 PF01261.24 ORY01954.1 - 0.014 14.8 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Ykof PF07615.11 ORY01954.1 - 0.02 15.4 0.0 0.041 14.4 0.0 1.5 2 0 0 2 2 2 0 YKOF-related Family DUF1330 PF07045.11 ORY01954.1 - 0.096 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Abhydrolase_3 PF07859.13 ORY01955.1 - 9.2e-24 84.5 0.0 2.3e-21 76.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY01955.1 - 7.2e-17 61.6 0.0 9.6e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ORY01955.1 - 1.9e-09 37.0 0.6 2.5e-08 33.3 0.2 2.4 2 1 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 ORY01955.1 - 1.3e-06 28.2 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ORY01955.1 - 6e-06 25.7 0.0 0.12 11.6 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORY01955.1 - 8.6e-06 25.8 0.0 0.00024 21.1 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ORY01955.1 - 1.8e-05 25.5 0.0 2.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY01955.1 - 2.4e-05 24.1 0.0 0.00037 20.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY01955.1 - 4.2e-05 23.3 0.0 0.00046 19.9 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 ORY01955.1 - 9e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 ORY01955.1 - 0.0002 21.3 0.3 0.8 9.5 0.1 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 ORY01955.1 - 0.0018 18.0 0.1 0.016 14.8 0.1 2.6 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 ORY01955.1 - 0.0044 15.9 0.0 0.0087 15.0 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF2920 PF11144.8 ORY01955.1 - 0.047 12.9 0.0 3.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) HAGH_C PF16123.5 ORY01956.1 - 1.4e-26 92.8 0.0 2.9e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY01956.1 - 1.6e-15 57.7 1.0 6.4e-15 55.7 1.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY01956.1 - 0.00025 20.6 0.3 0.0016 18.0 0.3 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY01956.1 - 0.003 17.5 0.1 0.0085 16.0 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain LPMO_10 PF03067.15 ORY01957.1 - 0.00027 21.6 1.0 0.00075 20.2 0.0 2.2 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY01957.1 - 0.027 14.4 0.1 0.18 11.7 0.1 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Herpes_pp85 PF04637.12 ORY01957.1 - 0.47 8.8 0.5 0.62 8.4 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mucin PF01456.17 ORY01957.1 - 1.7 8.6 10.5 2.7 8.0 10.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein LPMO_10 PF03067.15 ORY01958.1 - 0.00029 21.5 0.7 0.00077 20.2 0.0 2.1 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY01958.1 - 0.032 14.2 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Herpes_pp85 PF04637.12 ORY01958.1 - 0.61 8.4 1.1 0.77 8.1 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RS4NT PF08071.12 ORY01959.1 - 0.11 12.7 0.3 0.22 11.6 0.3 1.6 1 1 0 1 1 1 0 RS4NT (NUC023) domain GDPD PF03009.17 ORY01960.1 - 1.3e-32 113.6 0.0 1.4e-28 100.4 0.1 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family zf-CCCH PF00642.24 ORY01961.1 - 4.2e-20 71.1 18.8 1.2e-10 41.1 6.4 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY01961.1 - 4.4e-12 45.6 15.5 1e-07 31.7 4.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORY01961.1 - 7.9e-08 31.9 16.6 0.0003 20.5 4.6 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORY01961.1 - 0.0017 19.1 12.2 0.087 13.5 2.7 2.0 1 1 1 2 2 2 2 Torus domain Defensin_int PF17858.1 ORY01961.1 - 0.024 14.6 2.4 0.15 12.1 0.7 2.1 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-CCCH_2 PF14608.6 ORY01961.1 - 0.042 14.3 1.3 0.042 14.3 1.3 2.8 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger AWS PF17907.1 ORY01961.1 - 1.1 9.4 8.0 4.4 7.4 1.4 2.4 2 1 0 2 2 2 0 AWS domain CBAH PF02275.18 ORY01962.1 - 0.02 14.6 0.2 0.027 14.1 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family AMP-binding PF00501.28 ORY02001.1 - 0 1327.3 0.0 6.9e-101 337.9 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 ORY02001.1 - 0 1270.5 20.9 2.6e-116 389.0 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 ORY02001.1 - 1.5e-49 166.2 3.2 1.3e-12 47.9 0.3 5.5 5 0 0 5 5 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORY02001.1 - 6.6e-44 148.8 5.1 4.2e-09 37.2 0.0 8.1 8 0 0 8 8 7 6 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.12 ORY02001.1 - 1.1e-33 115.9 0.0 4.4e-15 56.2 0.0 3.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02001.1 - 4.9e-28 97.7 0.0 7.3e-12 45.8 0.0 4.5 5 0 0 5 5 3 2 Methyltransferase domain Thioesterase PF00975.20 ORY02001.1 - 2.6e-27 96.4 0.0 7.6e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Methyltransf_11 PF08241.12 ORY02001.1 - 4.7e-26 91.3 0.1 2.2e-10 41.0 0.0 5.0 5 0 0 5 5 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02001.1 - 1.5e-21 76.8 0.2 5.1e-09 36.1 0.0 3.6 3 0 0 3 3 3 2 Methyltransferase domain NodS PF05401.11 ORY02001.1 - 2.9e-20 72.7 0.0 2.4e-08 33.9 0.0 3.4 3 0 0 3 3 3 2 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 ORY02001.1 - 2.5e-16 60.0 0.1 1.7e-06 28.0 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.14 ORY02001.1 - 6.8e-09 35.5 0.0 0.0056 16.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase small domain CheR PF01739.18 ORY02001.1 - 1.3e-06 28.1 0.1 0.087 12.3 0.0 2.9 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain Abhydrolase_6 PF12697.7 ORY02001.1 - 1.8e-05 25.5 0.0 6.4e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CMAS PF02353.20 ORY02001.1 - 0.00044 19.6 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ORY02001.1 - 0.0015 18.0 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 Putative methyltransferase Phage_int_SAM_2 PF12834.7 ORY02001.1 - 0.0062 17.2 0.2 74 4.1 0.0 4.0 3 0 0 3 3 3 0 Phage integrase, N-terminal IMS PF00817.20 ORY02001.1 - 0.023 14.7 0.2 0.66 10.0 0.0 3.4 4 0 0 4 4 4 0 impB/mucB/samB family DUF2974 PF11187.8 ORY02001.1 - 0.03 13.9 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Nup35_RRM PF05172.13 ORY02001.1 - 0.032 14.2 0.7 4.1 7.4 0.0 3.8 4 0 0 4 4 3 0 Nup53/35/40-type RNA recognition motif HicB-like_2 PF15970.5 ORY02001.1 - 0.033 14.3 0.0 18 5.6 0.0 2.8 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Flg_hook PF02120.16 ORY02001.1 - 0.035 14.0 3.0 37 4.3 0.1 4.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK BspA_v PF18220.1 ORY02001.1 - 0.036 14.2 0.2 0.14 12.3 0.2 2.0 1 0 0 1 1 1 0 Adhesin BspA variable domain rRNA_methylase PF06962.12 ORY02001.1 - 0.045 13.7 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Putative rRNA methylase Cytochrom_B_N_2 PF13631.6 ORY02001.1 - 0.061 13.3 0.0 82 3.1 0.0 3.7 4 0 0 4 4 4 0 Cytochrome b(N-terminal)/b6/petB LRRNT PF01462.18 ORY02001.1 - 0.091 12.4 0.0 1.2e+02 2.5 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Abhydrolase_1 PF00561.20 ORY02001.1 - 0.099 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2108 PF09881.9 ORY02001.1 - 0.33 11.0 1.2 1.5e+02 2.4 0.0 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2108) FTO_CTD PF12934.7 ORY02001.1 - 0.55 10.0 9.2 5.8 6.6 0.2 3.4 3 0 0 3 3 3 0 FTO C-terminal domain DRE2_N PF16803.5 ORY02001.1 - 0.96 9.7 4.8 51 4.1 0.1 5.3 5 1 1 6 6 5 0 Fe-S cluster assembly protein DRE2 N-terminus zf-RING_2 PF13639.6 ORY02002.1 - 5.5e-14 52.2 7.8 7.9e-14 51.7 6.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 ORY02002.1 - 6.8e-11 41.7 4.5 6.8e-11 41.7 4.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY02002.1 - 2.8e-09 36.7 5.0 5.4e-09 35.8 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY02002.1 - 2.5e-08 33.6 6.8 2.8e-08 33.4 5.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 ORY02002.1 - 9.8e-08 31.9 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 ORY02002.1 - 1.5e-07 31.3 3.5 2.6e-07 30.5 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY02002.1 - 2.8e-07 30.7 8.0 4.7e-07 30.0 6.7 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY02002.1 - 0.00013 22.0 3.1 0.00017 21.6 2.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY02002.1 - 0.00023 20.9 6.8 0.00043 20.1 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY02002.1 - 0.00048 19.9 7.1 0.001 18.9 7.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY02002.1 - 0.00062 19.7 1.3 0.00062 19.7 1.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 ORY02002.1 - 0.019 14.8 6.7 0.036 13.8 6.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORY02002.1 - 0.02 15.0 2.0 0.05 13.7 2.0 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 ORY02002.1 - 0.038 13.9 4.5 0.073 13.0 4.5 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 ORY02002.1 - 0.15 11.7 4.0 0.31 10.7 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY02002.1 - 0.16 12.2 5.9 1.3 9.2 6.0 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain PMP1_2 PF08114.11 ORY02002.1 - 0.17 11.7 0.6 0.38 10.5 0.6 1.6 1 0 0 1 1 1 0 ATPase proteolipid family zf-RING-like PF08746.11 ORY02002.1 - 0.66 10.3 4.5 0.27 11.6 1.7 1.8 2 0 0 2 2 1 0 RING-like domain Mito_carr PF00153.27 ORY02003.1 - 6.1e-69 228.0 9.5 5.8e-24 83.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORY02003.1 - 1.3e-16 60.7 7.7 3.5e-09 37.0 3.4 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY02003.1 - 6.6e-15 53.7 10.6 6e-05 22.7 2.3 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 ORY02003.1 - 3.6e-14 51.2 13.2 1.5e-06 27.3 2.8 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY02003.1 - 5e-09 35.9 6.6 1.6e-05 24.7 0.6 4.4 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY02003.1 - 7.3e-07 28.4 18.2 0.00013 21.2 2.5 4.7 4 1 1 5 5 5 3 EF hand EF-hand_10 PF14788.6 ORY02003.1 - 2e-05 24.3 9.7 0.0037 17.1 0.2 3.6 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 ORY02003.1 - 7.6e-05 23.0 5.8 0.013 15.9 2.6 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY02003.1 - 0.0036 17.2 7.6 0.021 14.8 3.0 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY02003.1 - 0.0043 17.3 0.4 0.072 13.4 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain Tim17 PF02466.19 ORY02003.1 - 1 9.8 5.2 2.3 8.6 0.4 2.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Sulfate_transp PF00916.20 ORY02004.1 - 2.1e-106 355.9 15.6 2.7e-106 355.5 15.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY02004.1 - 1.1e-12 47.6 0.0 2.4e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY02004.1 - 3.5e-06 27.4 2.2 3.5e-06 27.4 2.2 2.8 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily Adeno_E3_CR2 PF02439.15 ORY02005.1 - 0.00073 19.3 4.4 0.002 17.8 4.4 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 ORY02005.1 - 0.0036 17.1 0.2 0.0064 16.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TMEM51 PF15345.6 ORY02005.1 - 0.039 13.8 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 ORY02005.1 - 0.039 14.8 0.2 0.19 12.6 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 ORY02005.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EB PF01683.18 ORY02005.1 - 3 8.2 44.4 29 5.0 20.6 4.2 1 1 2 3 3 3 0 EB module SKG6 PF08693.10 ORY02005.1 - 4.6 6.7 9.3 8.9 5.8 9.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PDZ_1 PF12812.7 ORY02006.1 - 1.7e-37 127.3 0.0 1.7e-23 82.4 0.0 2.9 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 ORY02006.1 - 5e-22 79.4 0.0 3.3e-19 70.3 0.1 3.1 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ORY02006.1 - 5.7e-19 68.2 0.0 3.5e-08 33.7 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 ORY02006.1 - 2.1e-16 59.5 0.0 2.6e-08 33.6 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ORY02006.1 - 1.9e-12 47.4 0.0 8.6e-07 29.2 0.0 3.4 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 ORY02006.1 - 0.0046 16.8 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 ORY02006.1 - 0.011 15.6 0.1 9.4 6.3 0.0 3.3 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ORY02006.1 - 0.085 11.5 0.1 1.9 7.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 PDZ_3 PF17815.1 ORY02006.1 - 0.17 11.8 0.0 15 5.4 0.0 3.0 3 1 1 4 4 4 0 PDZ domain SNARE_assoc PF09335.11 ORY02007.1 - 1.1e-16 61.4 6.6 1.1e-16 61.4 6.6 2.2 1 1 1 2 2 2 1 SNARE associated Golgi protein CM2 PF03021.14 ORY02007.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Influenza C virus M2 protein FixQ PF05545.11 ORY02007.1 - 0.29 11.1 1.0 0.86 9.6 1.0 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ MspA PF09203.11 ORY02008.1 - 0.017 15.0 3.4 0.033 14.0 3.4 1.4 1 1 0 1 1 1 0 MspA DDA1 PF10172.9 ORY02009.1 - 9.1e-13 48.3 0.1 1.6e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Phytochelatin PF05023.14 ORY02011.1 - 8.4e-70 234.3 0.0 9.8e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 ORY02011.1 - 9e-05 23.1 0.0 0.00022 21.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase_C39 like family DUF1604 PF07713.13 ORY02011.1 - 0.089 12.6 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) ThrE PF06738.12 ORY02012.1 - 8.2e-48 162.9 20.5 7.5e-45 153.2 1.5 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY02012.1 - 1.2e-11 44.8 29.5 7.9e-08 32.5 12.7 2.2 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Met_synt_B12 PF02965.17 ORY02013.1 - 5.9e-122 406.4 0.0 1.1e-121 405.6 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 ORY02013.1 - 5.5e-80 269.0 0.0 1.2e-79 268.0 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 ORY02013.1 - 4.7e-56 190.2 1.6 1.2e-55 188.9 0.9 2.1 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.17 ORY02013.1 - 9e-23 80.5 0.0 5.3e-22 78.0 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 ORY02013.1 - 3.5e-20 72.3 0.9 3.2e-19 69.1 0.4 2.8 2 0 0 2 2 2 1 B12 binding domain MtrH PF02007.18 ORY02013.1 - 0.00035 19.8 0.1 0.0011 18.2 0.1 1.8 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit F-box-like PF12937.7 ORY02014.1 - 8.5e-09 35.2 2.2 2.4e-08 33.8 2.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY02014.1 - 0.0021 18.4 20.5 0.074 13.5 0.2 8.4 7 2 3 10 10 10 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY02014.1 - 0.23 11.2 9.3 0.95 9.3 0.2 5.6 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 ORY02014.1 - 0.29 11.3 6.6 37 4.7 0.0 5.8 5 0 0 5 5 5 0 Leucine Rich repeat SKG6 PF08693.10 ORY02015.1 - 0.0014 18.0 0.5 0.0014 18.0 0.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Pkinase PF00069.25 ORY02016.1 - 5.6e-56 189.8 0.0 7.9e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02016.1 - 3.3e-30 105.3 0.0 4.5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY02016.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORY02016.1 - 0.059 13.0 0.1 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 ORY02016.1 - 0.061 13.2 0.2 0.33 10.8 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY02016.1 - 0.091 12.1 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Protoglobin PF11563.8 ORY02018.1 - 8.3e-40 136.3 2.1 1.3e-38 132.3 0.6 2.4 2 1 1 3 3 3 1 Protoglobin Bac_globin PF01152.21 ORY02018.1 - 2e-15 57.0 0.0 4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial-like globin tRNA-synt_1e PF01406.19 ORY02018.1 - 0.07 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SPT_ssu-like PF11779.8 ORY02019.1 - 1.4e-17 63.0 4.0 1.8e-17 62.7 4.0 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like E1_dh PF00676.20 ORY02020.1 - 1.2e-100 336.3 0.1 1.4e-100 336.1 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 ORY02020.1 - 1.1e-05 24.6 0.1 1.1e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 ORY02020.1 - 2.1e-05 24.4 0.4 0.00027 20.7 0.4 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORY02020.1 - 3.1e-05 23.3 0.0 0.00013 21.3 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase SDF PF00375.18 ORY02021.1 - 3.3e-101 339.1 40.5 3.8e-101 339.0 40.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF1958 PF09211.10 ORY02021.1 - 0.084 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) Snf7 PF03357.21 ORY02022.1 - 6.1e-46 156.2 12.7 7e-46 156.0 12.7 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 ORY02022.1 - 0.0038 17.7 4.3 0.14 12.6 1.1 3.0 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.11 ORY02022.1 - 0.076 13.2 2.5 0.13 12.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Prefoldin PF02996.17 ORY02022.1 - 0.22 11.4 9.2 3 7.8 0.1 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF4094 PF13334.6 ORY02022.1 - 0.26 11.8 4.5 0.39 11.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2312 PF10073.9 ORY02022.1 - 0.3 10.7 10.5 1.2 8.9 0.3 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) TBCA PF02970.16 ORY02022.1 - 0.51 10.7 6.9 1.3 9.4 6.9 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF848 PF05852.11 ORY02022.1 - 1.4 9.0 7.9 0.58 10.3 4.5 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Macoilin PF09726.9 ORY02022.1 - 3.3 6.2 10.7 5.4 5.4 10.7 1.3 1 1 0 1 1 1 0 Macoilin family FlxA PF14282.6 ORY02022.1 - 3.8 7.5 11.3 1.8 8.6 4.9 2.3 1 1 1 2 2 2 0 FlxA-like protein FlaC_arch PF05377.11 ORY02022.1 - 8.2 6.9 6.7 27 5.2 0.0 3.6 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) YafO_toxin PF13957.6 ORY02023.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system LRR_6 PF13516.6 ORY02024.1 - 0.015 15.3 8.2 0.05 13.7 0.0 5.8 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.7 ORY02024.1 - 0.99 9.9 8.9 7.4 7.2 0.0 5.6 5 3 0 5 5 5 0 Leucine Rich repeats (2 copies) IDO PF01231.18 ORY02025.1 - 4e-49 167.6 0.0 5.4e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cry1Ac_D5 PF17997.1 ORY02025.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 HAGH_C PF16123.5 ORY02028.1 - 3.2e-25 88.5 0.1 4.9e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY02028.1 - 3.1e-14 53.4 1.5 2.3e-13 50.6 1.5 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY02028.1 - 0.00025 20.6 1.3 0.0049 16.4 0.9 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY02028.1 - 0.00077 19.4 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAM221 PF14753.6 ORY02028.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein FAM221A/B tRNA_anti-like PF12869.7 ORY02029.1 - 0.061 12.9 0.0 0.28 10.8 0.0 2.1 1 1 1 2 2 2 0 tRNA_anti-like TFIIA PF03153.13 ORY02029.1 - 0.075 13.0 40.5 0.09 12.8 40.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 ORY02029.1 - 0.91 7.7 26.8 0.96 7.6 26.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 ORY02029.1 - 2.4 5.2 9.3 2.6 5.1 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-5a PF01287.20 ORY02081.1 - 1.1e-28 99.1 0.8 1.6e-28 98.6 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORY02081.1 - 0.0057 16.7 0.7 0.0093 16.0 0.1 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain zf-Tim10_DDP PF02953.15 ORY02082.1 - 5.4e-23 80.4 0.3 6.6e-23 80.1 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger IF-2B PF01008.17 ORY02083.1 - 3.5e-74 249.5 0.1 4.2e-74 249.3 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.27 ORY02084.1 - 6.9e-66 221.5 0.1 9.9e-66 221.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY02084.1 - 1.3e-33 115.4 0.0 4.4e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY02084.1 - 4.9e-22 77.8 0.0 2e-21 75.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORY02084.1 - 1.8e-13 50.4 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ORY02084.1 - 7.2e-13 48.7 0.0 2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY02084.1 - 2.1e-06 27.8 0.2 4.1e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase CAP PF00188.26 ORY02085.1 - 2.6e-15 57.4 0.6 3.2e-15 57.1 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORY02086.1 - 2.6e-15 57.4 0.6 3.2e-15 57.1 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TMEM223 PF14640.6 ORY02087.1 - 3.2e-21 76.2 0.0 4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 LNS2 PF08235.13 ORY02088.1 - 3e-100 334.4 0.0 4.2e-100 333.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 ORY02088.1 - 9.4e-44 147.6 0.0 2.5e-42 143.0 0.0 2.3 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 ORY02088.1 - 2.6e-20 72.4 0.0 6.4e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Trp_leader1 PF08055.11 ORY02088.1 - 0.13 12.0 0.6 0.29 10.9 0.6 1.6 1 0 0 1 1 1 0 Tryptophan leader peptide Transcrip_reg PF01709.20 ORY02090.1 - 1.5e-78 263.6 0.6 1.6e-78 263.4 0.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF223 PF02721.14 ORY02090.1 - 0.0021 18.3 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF223 DPBB_1 PF03330.18 ORY02091.1 - 9.7e-10 38.6 0.2 1.1e-09 38.4 0.2 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY02091.1 - 1.7e-05 24.7 0.1 1.9e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family FhuF_C PF11575.8 ORY02091.1 - 0.31 11.0 2.2 65 3.6 0.0 3.1 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DPBB_1 PF03330.18 ORY02092.1 - 1e-08 35.3 0.1 1.7e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY02092.1 - 6.9e-05 22.7 0.3 9.7e-05 22.2 0.3 1.4 1 1 0 1 1 1 1 Barwin family Mitofilin PF09731.9 ORY02093.1 - 4.1e-89 300.1 21.7 1.6e-77 261.8 19.0 2.4 1 1 1 2 2 2 2 Mitochondrial inner membrane protein AAA_32 PF13654.6 ORY02093.1 - 0.018 13.9 8.5 0.029 13.2 8.5 1.4 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 ORY02093.1 - 0.085 12.4 6.6 0.18 11.3 6.6 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit TipAS PF07739.13 ORY02093.1 - 0.098 13.2 7.9 4 8.0 6.0 2.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain MttA_Hcf106 PF02416.16 ORY02093.1 - 0.11 11.8 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family Endotoxin_N PF03945.14 ORY02093.1 - 0.15 11.7 5.8 14 5.3 0.0 2.8 2 1 0 2 2 2 0 delta endotoxin, N-terminal domain MAGI_u5 PF16666.5 ORY02093.1 - 0.15 12.2 1.3 0.37 10.9 1.3 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI FAD_SOX PF18371.1 ORY02093.1 - 0.28 11.5 2.3 0.78 10.1 0.1 2.6 1 1 1 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Spore_III_AF PF09581.10 ORY02093.1 - 0.43 10.6 7.0 0.099 12.7 2.4 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) L27_1 PF09058.10 ORY02093.1 - 0.66 10.0 7.6 0.46 10.5 1.5 3.8 5 0 0 5 5 5 0 L27_1 DUF4404 PF14357.6 ORY02093.1 - 1.5 9.6 14.2 2.7 8.7 0.1 4.1 3 1 1 4 4 3 0 Domain of unknown function (DUF4404) DUF1910 PF08928.10 ORY02093.1 - 1.6 8.8 5.4 9 6.3 5.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Mer2 PF09074.10 ORY02093.1 - 4.7 7.0 16.8 0.32 10.8 5.8 3.0 2 1 1 3 3 3 0 Mer2 SbsC_C PF18058.1 ORY02093.1 - 7.3 6.8 15.2 1.3 9.3 10.1 2.4 3 0 0 3 3 3 0 SbsC C-terminal domain Dak2 PF02734.17 ORY02093.1 - 8.4 6.3 7.5 20 5.0 0.2 3.0 2 1 1 3 3 3 0 DAK2 domain 3Beta_HSD PF01073.19 ORY02094.1 - 7.2e-16 58.0 0.0 4.4e-10 39.0 0.1 2.1 1 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY02094.1 - 7.8e-14 51.7 0.0 2.6e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY02094.1 - 6.3e-12 45.2 0.0 1.5e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY02094.1 - 1.5e-10 41.3 1.6 1.2e-09 38.3 1.1 2.5 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ORY02094.1 - 6.8e-06 25.8 0.3 4e-05 23.3 0.5 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 ORY02094.1 - 0.00012 21.3 0.2 2.4 7.2 0.2 3.7 2 1 2 4 4 4 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY02094.1 - 0.0003 20.3 0.4 0.00066 19.2 0.3 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 ORY02094.1 - 0.002 18.1 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 KR domain zf-C2H2 PF00096.26 ORY02095.1 - 7.3e-06 26.2 13.6 0.0032 17.8 1.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORY02095.1 - 9.3e-05 22.6 10.3 0.029 14.5 0.4 2.8 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORY02095.1 - 0.0011 19.6 16.9 0.045 14.6 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY02095.1 - 0.0049 17.5 7.3 0.27 11.9 0.0 3.3 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY02095.1 - 0.076 13.3 1.1 0.17 12.2 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon OrsD PF12013.8 ORY02095.1 - 2.3 8.7 4.8 12 6.4 0.2 2.9 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D OTU PF02338.19 ORY02096.1 - 8.6e-25 87.7 1.4 1.2e-24 87.2 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Lipid_bd PF12888.7 ORY02096.1 - 0.012 16.1 0.8 0.046 14.2 0.1 2.2 1 1 1 2 2 2 0 Lipid-binding putative hydrolase Peptidase_C65 PF10275.9 ORY02096.1 - 0.28 10.6 6.2 0.032 13.7 0.7 2.1 2 1 0 2 2 2 0 Peptidase C65 Otubain ZYG-11_interact PF05884.12 ORY02096.1 - 0.28 10.6 2.0 0.4 10.1 2.0 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 LETM1 PF07766.13 ORY02096.1 - 1.3 8.3 11.6 5.3 6.3 0.0 3.1 3 0 0 3 3 3 0 LETM1-like protein OmpH PF03938.14 ORY02096.1 - 4.7 7.5 32.7 1.7 9.0 16.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SPT16 PF08644.11 ORY02096.1 - 5.9 7.1 13.4 0.24 11.6 5.5 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF2335 PF10097.9 ORY02096.1 - 7.6 6.6 8.3 9 6.4 1.9 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Mito_carr PF00153.27 ORY02097.1 - 1.2e-62 207.8 2.0 5.5e-21 74.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY02097.1 - 0.00087 18.5 1.5 5.1 6.2 0.0 3.2 2 1 1 3 3 3 3 Gammaproteobacterial serine protease PetG PF02529.15 ORY02097.1 - 0.017 15.0 0.0 0.059 13.2 0.0 1.9 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 SLR1-BP PF07333.12 ORY02098.1 - 0.069 13.6 1.4 0.069 13.6 1.4 1.8 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) UQ_con PF00179.26 ORY02099.1 - 1.6e-53 180.2 0.0 1.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY02099.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY02099.1 - 0.088 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ORY02099.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain RasGEF PF00617.19 ORY02100.1 - 4.6e-13 49.8 0.0 4.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain Thiolase_N PF00108.23 ORY02101.1 - 1.2e-15 57.6 0.1 4.4e-13 49.2 0.0 2.2 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY02101.1 - 4.1e-11 42.6 0.3 4e-10 39.4 0.3 2.4 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORY02101.1 - 0.00025 20.8 0.1 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ORY02101.1 - 0.009 15.6 0.3 0.049 13.2 0.0 2.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY02101.1 - 0.015 15.3 0.2 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DMT_YdcZ PF04657.13 ORY02102.1 - 4.6e-34 117.7 12.4 5.3e-34 117.5 12.4 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ MS_channel PF00924.18 ORY02103.1 - 2.8e-23 82.6 0.1 4.7e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel MerC PF03203.14 ORY02103.1 - 0.011 16.2 0.3 0.011 16.2 0.3 1.9 2 0 0 2 2 2 0 MerC mercury resistance protein CAP_C PF08603.11 ORY02103.1 - 0.037 13.6 0.3 0.065 12.9 0.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF1129 PF06570.11 ORY02103.1 - 0.12 11.9 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Abhydrolase_9_N PF15420.6 ORY02103.1 - 0.2 11.6 1.5 0.32 11.0 1.5 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Zn_clus PF00172.18 ORY02104.1 - 4.2e-06 26.8 10.9 6.3e-06 26.2 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain hnRNP_Q_AcD PF18360.1 ORY02105.1 - 0.014 15.3 0.1 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Acetyltransf_9 PF13527.7 ORY02105.1 - 0.036 14.2 0.1 0.11 12.6 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2043 PF09740.9 ORY02106.1 - 1.4e-29 102.9 0.0 5.9e-29 100.9 0.0 2.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) QSregVF PF13652.6 ORY02106.1 - 0.072 13.1 0.3 0.59 10.2 0.0 2.5 3 0 0 3 3 3 0 Putative quorum-sensing-regulated virulence factor CBFD_NFYB_HMF PF00808.23 ORY02107.1 - 8.7e-19 67.6 1.8 1.4e-18 66.9 1.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY02107.1 - 0.013 15.8 1.2 0.054 13.8 0.1 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 ORY02107.1 - 0.021 14.8 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Vps54 PF07928.12 ORY02107.1 - 0.068 13.6 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 Vps54-like protein Maf1 PF09174.10 ORY02108.1 - 8.7e-62 208.3 0.8 1.2e-61 207.9 0.8 1.2 1 0 0 1 1 1 1 Maf1 regulator Cnd1 PF12717.7 ORY02109.1 - 2.9e-50 170.5 14.4 9.1e-48 162.3 0.3 4.2 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 ORY02109.1 - 2.7e-38 131.4 0.7 7.2e-38 130.1 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 ORY02109.1 - 3.7e-10 39.2 0.3 0.0011 19.1 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 ORY02109.1 - 5.6e-09 36.3 0.1 0.034 14.5 0.0 4.9 4 0 0 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 ORY02109.1 - 1.8e-06 26.8 11.3 0.00018 20.3 0.7 4.5 2 1 2 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 ORY02109.1 - 0.00011 22.3 0.1 0.35 11.1 0.0 3.5 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 ENTH PF01417.20 ORY02109.1 - 0.00017 21.6 0.8 0.64 10.1 0.0 4.6 4 1 1 5 5 5 1 ENTH domain Cnd3 PF12719.7 ORY02109.1 - 0.0014 17.9 7.8 0.0018 17.5 0.7 3.6 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 ORY02109.1 - 0.0014 19.0 0.1 1.3 9.6 0.0 3.9 2 1 0 2 2 2 1 HEAT-like repeat DUF4042 PF13251.6 ORY02109.1 - 0.054 13.2 0.9 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.7 ORY02109.1 - 0.11 12.8 2.7 4.1 7.8 0.1 3.1 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion PqqD PF05402.12 ORY02109.1 - 0.28 11.5 1.2 6 7.2 0.0 3.7 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) CRAL_TRIO PF00650.20 ORY02110.1 - 2.2e-32 112.0 0.2 3.5e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY02110.1 - 4e-07 30.1 0.5 9.7e-07 28.9 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY02110.1 - 1.1e-05 25.7 0.1 1.7e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TACC_C PF05010.14 ORY02110.1 - 0.055 13.2 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PAP2_C PF14360.6 ORY02111.1 - 6e-16 58.7 11.3 6e-16 58.7 11.3 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORY02111.1 - 8.2e-05 22.4 4.9 8.2e-05 22.4 4.9 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORY02111.1 - 1.4 8.5 13.4 3.5 7.3 13.4 1.9 1 1 0 1 1 1 0 PAP2 superfamily IMS PF00817.20 ORY02112.1 - 7.7e-40 136.3 0.0 3.1e-39 134.4 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ORY02112.1 - 4.4e-11 43.5 0.4 1e-10 42.3 0.4 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORY02112.1 - 6.1e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DrrA_P4M PF14860.6 ORY02112.1 - 0.065 13.1 1.3 0.5 10.2 0.8 2.6 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain MerR-DNA-bind PF09278.11 ORY02112.1 - 0.17 12.4 1.0 0.42 11.2 0.3 2.0 2 0 0 2 2 2 0 MerR, DNA binding ABC_tran_CTD PF16326.5 ORY02112.1 - 1.7 9.0 5.1 3.7 7.9 1.3 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain SpoIIE PF07228.12 ORY02113.1 - 3.3e-13 50.0 0.0 4.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 ORY02113.1 - 5.2e-11 42.7 0.0 2.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY02113.1 - 1.5e-06 28.1 0.0 2.7e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C POTRA_1 PF08478.10 ORY02113.1 - 0.049 13.9 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, FtsQ-type Trehalase PF01204.18 ORY02114.1 - 4e-122 408.6 0.0 5.8e-121 404.8 0.0 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 ORY02114.1 - 0.0025 16.8 0.1 0.0053 15.7 0.1 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.16 ORY02114.1 - 1.8 7.3 7.7 0.21 10.3 0.1 2.8 3 1 1 4 4 4 0 Glycosyl hydrolase family 63 C-terminal domain GPR_Gpa2_C PF11970.8 ORY02115.1 - 3.2 7.9 6.9 0.34 11.0 1.2 2.3 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term MHYT PF03707.16 ORY02115.1 - 8.4 6.6 9.6 17 5.6 0.1 3.8 3 1 1 4 4 4 0 Bacterial signalling protein N terminal repeat DUF4743 PF15916.5 ORY02116.1 - 5e-18 65.2 0.0 7.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ORY02116.1 - 1.6e-06 28.2 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Imm39 PF15568.6 ORY02116.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 39 MMS1_N PF10433.9 ORY02118.1 - 3.3e-70 237.1 0.0 5.3e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY02118.1 - 9.7e-38 130.3 0.0 1.6e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region PQQ_3 PF13570.6 ORY02118.1 - 0.0036 17.8 2.9 6.1 7.5 0.1 4.6 4 0 0 4 4 4 2 PQQ-like domain O-FucT PF10250.9 ORY02122.1 - 0.00036 20.3 0.7 0.00072 19.4 0.7 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CBM_5_12 PF02839.14 ORY02149.1 - 2.9e-06 27.5 8.9 2.9e-06 27.5 8.9 1.7 2 1 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORY02149.1 - 0.0073 16.2 4.1 0.0089 15.9 4.1 1.2 1 0 0 1 1 1 1 Cellulose-binding domain Glyco_hydro_18 PF00704.28 ORY02150.1 - 6.1e-55 187.1 0.1 7.1e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_61 PF03443.14 ORY02151.1 - 0.0027 17.7 0.1 0.11 12.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORY02151.1 - 0.0032 18.2 0.7 0.021 15.5 0.7 2.0 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ceramidse_alk_C PF17048.5 ORY02151.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal GPI-anchored PF10342.9 ORY02151.1 - 0.13 13.0 0.0 0.23 12.2 0.0 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4042 PF13251.6 ORY02152.1 - 2.6 7.7 6.9 1.3 8.6 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) XendoU PF09412.10 ORY02153.1 - 6e-90 301.0 0.0 7.7e-90 300.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU PNPase_C PF12111.8 ORY02153.1 - 0.0007 19.0 1.0 0.0012 18.2 1.0 1.3 1 0 0 1 1 1 1 Polyribonucleotide phosphorylase C terminal ABC1 PF03109.16 ORY02154.1 - 1.3e-22 80.2 0.0 4.9e-22 78.3 0.0 2.0 1 1 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 ORY02154.1 - 0.018 14.3 0.1 0.26 10.5 0.1 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 ORY02154.1 - 0.054 12.8 0.4 0.6 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein kinase domain Peptidase_S8 PF00082.22 ORY02155.1 - 1.2e-31 110.1 8.3 2.2e-31 109.2 8.3 1.3 1 1 0 1 1 1 1 Subtilase family Fungal_trans PF04082.18 ORY02156.1 - 6.7e-44 149.9 0.0 1.4e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY02156.1 - 2.3e-12 46.8 11.2 4.1e-12 46.0 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_repr_REX1B PF14966.6 ORY02157.1 - 4.9e-22 78.4 4.4 4.9e-22 78.4 4.4 1.9 2 0 0 2 2 2 1 DNA repair REX1-B CheZ PF04344.13 ORY02157.1 - 0.00065 19.7 3.3 0.29 11.0 0.5 2.0 1 1 1 2 2 2 2 Chemotaxis phosphatase, CheZ EzrA PF06160.12 ORY02157.1 - 0.0093 14.2 11.7 0.014 13.6 11.7 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA C9orf72-like PF15019.6 ORY02157.1 - 0.01 15.4 0.2 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 C9orf72-like protein family Fib_alpha PF08702.10 ORY02157.1 - 0.019 15.2 3.0 0.019 15.2 3.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 ORY02157.1 - 0.022 15.3 3.8 0.42 11.2 0.7 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.14 ORY02157.1 - 0.053 13.9 6.6 0.075 13.4 6.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 ORY02157.1 - 0.082 13.6 6.8 0.42 11.4 6.8 2.3 1 1 0 1 1 1 0 Occludin homology domain WXG100 PF06013.12 ORY02157.1 - 0.1 12.8 0.7 0.82 9.9 0.1 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG UPF0242 PF06785.11 ORY02157.1 - 0.19 11.8 8.8 0.24 11.5 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 ORY02157.1 - 0.3 11.5 4.3 0.68 10.3 0.9 2.4 1 1 1 2 2 2 0 Syntaxin-like protein Inhibitor_I29 PF08246.12 ORY02157.1 - 0.81 10.2 3.4 5.5 7.5 1.5 2.3 1 1 1 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) tRNA-synt_2 PF00152.20 ORY02158.1 - 1.9e-72 244.0 0.0 2.4e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY02158.1 - 2e-10 40.5 0.1 4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY02158.1 - 0.00011 21.8 0.1 0.097 12.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) AA_permease_2 PF13520.6 ORY02159.1 - 1.4e-67 228.4 37.3 1.7e-67 228.2 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY02159.1 - 1.4e-25 89.8 31.3 1.8e-25 89.5 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 ORY02159.1 - 3.2e-05 23.2 15.4 3.2e-05 23.2 15.4 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family GATA PF00320.27 ORY02160.1 - 7.5e-16 57.4 7.3 1.5e-15 56.5 7.3 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORY02160.1 - 8.6e-12 45.2 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORY02160.1 - 3.9e-09 36.5 0.0 6.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORY02160.1 - 7.9e-07 29.3 0.0 4.2e-06 27.0 0.0 2.0 1 1 1 2 2 2 1 PAS domain PAS_11 PF14598.6 ORY02160.1 - 5.3e-05 23.3 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORY02160.1 - 0.057 13.7 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 PAS fold Zn-ribbon_8 PF09723.10 ORY02160.1 - 0.066 13.3 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2 PF00096.26 ORY02162.1 - 3.4e-20 71.3 25.2 3.1e-05 24.2 0.3 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY02162.1 - 3.4e-18 65.2 25.0 4.4e-06 26.9 1.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY02162.1 - 6.5e-10 39.0 23.6 0.01 16.6 0.7 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORY02162.1 - 2.3e-05 24.9 8.5 0.33 11.6 0.1 3.6 3 1 1 4 4 4 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY02162.1 - 0.00048 20.4 7.9 0.078 13.3 6.3 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY02162.1 - 0.002 18.4 6.9 1.4 9.3 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY02162.1 - 0.16 12.4 9.5 2.7 8.5 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORY02162.1 - 0.27 11.9 12.0 0.16 12.7 1.6 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORY02162.1 - 0.75 9.9 9.4 4.6 7.4 4.0 2.7 2 2 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 ORY02162.1 - 5.9 6.7 13.0 2.2 8.1 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type FtsH_ext PF06480.15 ORY02164.1 - 0.55 10.6 6.8 5.1 7.5 6.8 2.3 1 1 0 1 1 1 0 FtsH Extracellular GFO_IDH_MocA PF01408.22 ORY02165.1 - 5.5e-14 53.0 0.0 8.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY02165.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 ORY02166.1 - 1.2e-103 347.4 17.9 1.5e-103 347.1 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY02166.1 - 2.1e-33 115.7 24.9 2.1e-33 115.7 24.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY02166.1 - 2.5 6.8 18.4 2.2 7.1 3.4 2.9 2 1 1 3 3 3 0 MFS_1 like family His_Phos_2 PF00328.22 ORY02207.1 - 3e-28 99.3 0.0 1.2e-18 67.6 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Cellulase PF00150.18 ORY02208.1 - 6.8e-13 48.7 0.4 6.8e-13 48.7 0.4 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.28 ORY02209.1 - 9.2e-100 334.2 0.0 1.1e-99 333.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY02209.1 - 3.5e-16 59.9 0.0 7.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_2 PF07716.15 ORY02210.1 - 3e-06 27.2 14.6 3e-06 27.2 14.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY02210.1 - 1.3e-05 25.2 13.9 1.3e-05 25.2 13.9 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY02210.1 - 0.0084 16.6 11.0 0.02 15.4 11.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor LXG PF04740.12 ORY02210.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Pro_isomerase PF00160.21 ORY02211.1 - 1.9e-34 119.2 0.1 3.2e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY02211.1 - 2.8e-17 62.3 0.0 5.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.19 ORY02212.1 - 2.9e-20 72.8 0.0 4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY02213.1 - 7.5e-29 101.4 0.0 1.7e-28 100.2 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY02213.1 - 0.00048 19.5 0.9 0.13 11.5 1.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 ORY02213.1 - 0.00059 20.4 0.9 0.0017 18.9 0.9 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY02213.1 - 0.00089 18.6 0.4 0.0063 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ORY02213.1 - 0.00098 18.7 0.2 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 ORY02213.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 ORY02213.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_3_Rpc31 PF11705.8 ORY02213.1 - 0.014 15.6 6.2 0.023 15.0 6.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NAD_binding_8 PF13450.6 ORY02213.1 - 0.04 14.2 1.3 0.088 13.1 1.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Phenyl_P_gamma PF09662.10 ORY02213.1 - 0.066 13.4 0.0 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) NAD_binding_7 PF13241.6 ORY02213.1 - 0.14 12.6 0.1 0.33 11.4 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 ORY02213.1 - 0.18 11.4 1.3 0.47 10.1 1.3 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 ORY02213.1 - 0.55 9.4 1.8 0.61 9.3 0.5 1.6 2 0 0 2 2 2 0 Thi4 family Radial_spoke PF04712.12 ORY02213.1 - 1.9 7.3 12.1 0.51 9.2 9.5 1.5 2 0 0 2 2 2 0 Radial spokehead-like protein DAO PF01266.24 ORY02214.1 - 4.3e-32 112.1 0.0 5.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY02214.1 - 5.7e-05 22.5 0.3 0.0025 17.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY02214.1 - 0.0002 20.8 0.8 0.0076 15.5 1.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 ORY02214.1 - 0.00037 21.0 1.5 0.0013 19.2 1.5 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY02214.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 ORY02214.1 - 0.0014 18.2 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 ORY02214.1 - 0.0033 17.3 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY02214.1 - 0.0092 16.4 0.1 0.026 14.9 0.1 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORY02214.1 - 0.026 14.7 1.1 0.086 13.1 1.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY02214.1 - 0.031 13.3 0.1 0.046 12.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY02214.1 - 0.052 12.8 0.1 0.089 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY02214.1 - 0.055 12.7 0.5 0.11 11.7 0.5 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 ORY02214.1 - 0.16 11.4 0.0 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY02214.1 - 0.23 10.7 2.4 0.43 9.8 2.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY02214.1 - 0.33 9.6 0.8 0.47 9.1 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ORY02214.1 - 0.73 9.4 4.7 0.3 10.6 1.5 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ORY02214.1 - 1.2 8.8 4.6 0.79 9.3 1.4 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ISK_Channel PF02060.15 ORY02215.1 - 1.5 8.6 7.4 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 Slow voltage-gated potassium channel CBFB_NFYA PF02045.15 ORY02216.1 - 6.4e-30 103.6 8.6 9.1e-30 103.1 8.6 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_L19e PF01280.20 ORY02217.1 - 3.4e-65 218.5 10.6 3.4e-65 218.5 10.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e bZIP_1 PF00170.21 ORY02218.1 - 9.1e-13 48.1 14.1 2.4e-12 46.8 14.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 ORY02218.1 - 0.0084 15.8 6.8 0.0084 15.8 6.8 1.6 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 ORY02218.1 - 0.02 15.4 8.8 0.047 14.2 8.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY02218.1 - 0.041 14.0 21.7 0.074 13.1 19.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper SUI1 PF01253.22 ORY02218.1 - 0.065 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor SUI1 Glutaredoxin2_C PF04399.13 ORY02218.1 - 0.15 11.9 0.6 0.66 9.8 0.9 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain LETM1 PF07766.13 ORY02218.1 - 0.38 10.1 3.8 0.81 9.0 3.8 1.4 1 0 0 1 1 1 0 LETM1-like protein Vpu PF00558.19 ORY02218.1 - 0.45 10.3 6.7 1.2 8.9 6.7 1.7 1 0 0 1 1 1 0 Vpu protein TSC22 PF01166.18 ORY02218.1 - 1.1 9.6 10.4 1.1 9.7 6.3 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family TMPIT PF07851.13 ORY02218.1 - 1.2 8.3 2.6 2.3 7.4 2.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein ASD2 PF08687.11 ORY02218.1 - 1.3 8.5 14.8 1.9 8.0 14.8 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Goodbye PF17109.5 ORY02218.1 - 1.7 9.1 4.1 4.3 7.8 4.1 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain DUF4407 PF14362.6 ORY02218.1 - 2.4 7.4 7.1 3.4 6.9 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 ORY02218.1 - 5 7.8 9.3 0.37 11.5 3.9 1.8 2 0 0 2 2 2 0 Initiation control protein YabA DSPc PF00782.20 ORY02219.1 - 1.7e-32 112.1 0.0 2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY02219.1 - 0.0005 19.7 0.1 0.023 14.3 0.0 2.1 1 1 1 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY02219.1 - 0.0028 17.7 0.0 0.0049 16.9 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 ORY02219.1 - 0.034 14.5 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Rogdi_lz PF10259.9 ORY02220.1 - 1.2e-35 123.2 0.2 2e-35 122.5 0.2 1.3 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein LIAS_N PF16881.5 ORY02221.1 - 1e-27 96.7 0.2 2.4e-27 95.5 0.1 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ORY02221.1 - 1.8e-13 51.2 0.1 3.3e-13 50.3 0.1 1.5 2 0 0 2 2 2 1 Radical SAM superfamily HLH PF00010.26 ORY02222.1 - 1.1e-12 47.6 0.4 1.1e-12 47.6 0.4 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Fzo_mitofusin PF04799.13 ORY02222.1 - 0.076 12.6 2.2 0.1 12.2 2.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region MFS_1 PF07690.16 ORY02223.1 - 3.6e-41 141.3 25.2 3.9e-41 141.1 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HhH-GPD PF00730.25 ORY02224.1 - 3.3e-09 37.2 0.0 4.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Tho1_MOS11_C PF18592.1 ORY02225.1 - 1.9e-06 27.6 16.3 0.0023 17.7 0.3 4.5 3 2 2 5 5 5 2 Tho1/MOS11 C-terminal domain GGDEF_2 PF17853.1 ORY02225.1 - 0.1 12.8 0.2 28 5.0 0.0 3.1 2 2 1 3 3 3 0 GGDEF-like domain DUF3394 PF11874.8 ORY02225.1 - 0.11 12.2 0.4 3.5 7.3 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3394) MFS_1 PF07690.16 ORY02226.1 - 2.9e-33 115.3 36.7 3.8e-33 114.9 31.8 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY02226.1 - 8.8e-06 24.8 35.4 0.00028 19.9 12.3 3.3 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 ORY02226.1 - 0.0023 16.6 17.5 0.0023 16.6 17.5 3.3 1 1 1 3 3 3 1 MFS/sugar transport protein ATG22 PF11700.8 ORY02226.1 - 0.019 13.6 0.7 0.019 13.6 0.7 3.7 5 0 0 5 5 5 0 Vacuole effluxer Atg22 like FUN14 PF04930.15 ORY02226.1 - 0.047 14.1 1.8 0.16 12.4 0.0 2.8 3 1 1 4 4 4 0 FUN14 family SIT PF15330.6 ORY02226.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.4 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT FtsL PF04999.13 ORY02226.1 - 0.88 9.6 4.6 26 4.9 0.2 3.5 2 1 1 3 3 3 0 Cell division protein FtsL Ac76 PF05814.11 ORY02226.1 - 4.2 7.4 10.9 15 5.7 1.1 3.6 3 0 0 3 3 3 0 Orf76 (Ac76) C12orf66_like PF09404.10 ORY02227.1 - 2.7e-63 214.4 0.0 3.7e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like C2 PF00168.30 ORY02227.1 - 7.4e-06 26.2 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.24 ORY02228.1 - 6.6e-81 272.5 25.5 1.5e-79 268.0 25.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY02228.1 - 5.7e-22 78.1 33.0 5.7e-22 78.1 33.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 ORY02230.1 - 5.4e-44 149.9 0.0 6.2e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY02230.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like TPT PF03151.16 ORY02232.1 - 1.4e-31 109.9 16.6 1.9e-31 109.5 16.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY02232.1 - 3.6e-06 27.2 27.3 0.00011 22.4 14.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY02232.1 - 0.00013 21.3 18.2 0.00016 21.0 18.2 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 ORY02233.1 - 6.5e-39 134.0 22.4 8.4e-39 133.6 22.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY02233.1 - 1.3e-09 37.7 26.0 1.7e-09 37.4 26.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY02233.1 - 2.7e-09 37.3 34.4 0.00018 21.7 12.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family RPE65 PF03055.15 ORY02234.1 - 4.4e-113 378.9 0.0 5.1e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_61 PF03443.14 ORY02236.1 - 1.2e-05 25.4 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 ORY02237.1 - 2.9e-39 135.0 25.9 2.9e-39 135.0 25.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.8 ORY02237.1 - 0.1 12.7 0.1 6.5 6.9 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function YoqO PF14037.6 ORY02237.1 - 0.11 13.1 2.5 20 5.7 0.1 3.7 2 1 1 3 3 3 0 YoqO-like protein YqhR PF11085.8 ORY02237.1 - 4 7.4 8.4 5.5 6.9 5.7 2.7 2 1 1 3 3 3 0 Conserved membrane protein YqhR Ribosomal_L11 PF00298.19 ORY02238.1 - 1.3e-29 102.5 0.1 2.1e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 ORY02238.1 - 3.3e-28 97.3 0.5 4.9e-28 96.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DHHC PF01529.20 ORY02239.1 - 2.9e-18 66.2 31.2 6e-18 65.2 16.5 3.2 2 1 1 3 3 3 2 DHHC palmitoyltransferase PSI PF01437.25 ORY02239.1 - 0.0027 18.2 5.1 0.0027 18.2 5.1 1.6 2 0 0 2 2 2 1 Plexin repeat GPI2 PF06432.11 ORY02239.1 - 0.036 13.5 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase MGC-24 PF05283.11 ORY02239.1 - 0.079 13.4 1.2 0.12 12.8 1.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Met_10 PF02475.16 ORY02240.1 - 5.8e-75 251.4 0.1 1.3e-74 250.3 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ORY02240.1 - 0.0035 16.6 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 ORY02240.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MethyltransfD12 PF02086.15 ORY02240.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_23 PF13489.6 ORY02240.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ORY02240.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SAM_PNT PF02198.16 ORY02240.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AF0941-like PF14591.6 ORY02240.1 - 0.34 11.5 3.9 0.47 11.0 0.4 2.5 2 0 0 2 2 2 0 AF0941-like Rhodanese PF00581.20 ORY02241.1 - 2.7e-14 53.6 0.0 5.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain 2OG-FeII_Oxy_2 PF13532.6 ORY02242.1 - 5.2e-30 105.1 0.0 6.3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 ORY02242.1 - 0.0078 16.7 0.0 0.02 15.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TLD PF07534.16 ORY02243.1 - 1.3e-25 90.3 0.7 1.5e-25 90.0 0.7 1.1 1 0 0 1 1 1 1 TLD RGS PF00615.19 ORY02244.1 - 1.2e-13 51.3 1.2 1.8e-13 50.8 1.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain PRD_Mga PF08270.11 ORY02244.1 - 0.00011 22.0 0.1 0.00023 20.9 0.1 1.6 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) PRD domain Syndecan PF01034.20 ORY02244.1 - 0.47 10.4 0.1 0.47 10.4 0.1 2.7 3 0 0 3 3 3 0 Syndecan domain COMPASS-Shg1 PF05205.12 ORY02245.1 - 1.9e-12 47.8 6.2 3.2e-12 47.0 4.0 2.6 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1325 PF07039.11 ORY02245.1 - 4.6e-08 33.2 1.6 4.6e-08 33.2 1.6 1.9 2 0 0 2 2 2 1 SGF29 tudor-like domain zf-C2H2 PF00096.26 ORY02246.1 - 3e-17 62.0 21.3 2.7e-08 33.8 2.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY02246.1 - 8.7e-14 51.2 7.0 1.4e-08 34.8 0.5 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY02246.1 - 3.5e-12 46.1 18.8 0.00016 22.3 1.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY02246.1 - 7.3e-09 35.7 7.1 0.051 13.9 0.3 3.2 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY02246.1 - 8.6e-08 32.0 14.5 0.00023 21.1 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORY02246.1 - 0.002 18.5 11.1 1.4 9.4 0.7 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY02246.1 - 0.0037 17.5 7.0 0.025 14.9 7.0 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 ORY02246.1 - 0.0068 16.7 5.3 5.9 7.3 4.9 3.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 ORY02246.1 - 0.01 16.1 3.4 0.26 11.5 1.0 2.1 2 0 0 2 2 2 1 TFIIH C1-like domain FOXP-CC PF16159.5 ORY02246.1 - 0.018 15.6 1.1 0.044 14.4 0.3 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-LYAR PF08790.11 ORY02246.1 - 0.084 12.8 7.4 0.9 9.5 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_ZIC PF18366.1 ORY02246.1 - 0.1 12.7 3.4 5.7 7.1 0.1 2.5 3 0 0 3 3 3 0 Zic proteins zinc finger domain C5HCH PF17982.1 ORY02246.1 - 1.1 9.4 13.0 0.2 11.9 1.7 2.8 1 1 2 3 3 3 0 NSD Cys-His rich domain zf-H2C2_5 PF13909.6 ORY02246.1 - 2.3 8.1 18.1 0.19 11.5 3.3 3.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 ORY02246.1 - 6.9 6.9 10.3 11 6.3 4.5 2.9 1 1 1 2 2 2 0 AN1-like Zinc finger Glyoxal_oxid_N PF07250.11 ORY02248.1 - 4.8e-56 189.6 0.0 2e-53 181.1 0.1 3.6 2 2 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY02248.1 - 1.2e-27 96.0 0.1 1.3e-26 92.7 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 ORY02248.1 - 0.0011 19.0 0.5 0.95 9.5 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY02248.1 - 0.0027 17.6 0.0 14 5.9 0.0 4.6 4 0 0 4 4 4 1 Kelch motif DUF5122 PF17164.4 ORY02248.1 - 0.014 15.6 0.4 7.8 6.9 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Kelch_6 PF13964.6 ORY02248.1 - 0.031 14.6 0.8 38 4.8 0.0 4.7 4 1 1 5 5 5 0 Kelch motif DUF1295 PF06966.12 ORY02249.1 - 5.4e-41 140.7 12.3 6.7e-41 140.3 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORY02249.1 - 0.00024 21.4 0.1 0.0011 19.4 0.1 2.2 1 0 0 1 1 1 1 Phospholipid methyltransferase Zn_peptidase_2 PF04298.12 ORY02249.1 - 0.16 11.4 0.2 0.69 9.3 0.1 2.0 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase ICMT PF04140.14 ORY02249.1 - 0.17 12.3 0.0 0.17 12.3 0.0 2.8 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family HhH-GPD PF00730.25 ORY02250.1 - 4e-17 62.6 0.0 6.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY02250.1 - 2.4e-09 36.6 0.0 1.9e-08 33.7 0.0 2.4 2 1 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ORY02250.1 - 0.00055 20.2 2.3 0.001 19.3 2.3 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 ORY02250.1 - 0.016 15.8 0.3 0.24 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain DAO PF01266.24 ORY02251.1 - 1.8e-61 208.7 0.0 2e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY02251.1 - 1.2e-05 24.7 0.1 0.0045 16.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY02251.1 - 1.4e-05 25.2 0.1 3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY02251.1 - 0.00048 20.6 0.7 0.0025 18.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY02251.1 - 0.00063 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.24 ORY02251.1 - 0.0008 18.6 1.1 0.0036 16.5 1.1 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY02251.1 - 0.0089 15.4 0.8 0.08 12.3 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 ORY02251.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 ORY02251.1 - 0.014 14.7 0.1 0.082 12.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ORY02251.1 - 0.019 15.2 1.1 0.19 12.0 0.3 2.3 1 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 ORY02251.1 - 0.027 13.7 0.1 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 ORY02251.1 - 0.027 14.5 0.1 0.11 12.5 0.2 1.9 1 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY02251.1 - 0.034 12.9 0.1 0.17 10.5 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 ORY02251.1 - 0.039 13.2 0.4 0.13 11.5 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 ORY02251.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ORY02251.1 - 0.098 11.7 0.3 1.2 8.1 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein WD40 PF00400.32 ORY02252.1 - 6.4e-08 33.1 0.5 0.18 12.7 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02252.1 - 2.9e-07 30.7 0.0 0.004 17.4 0.1 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY02252.1 - 0.14 11.5 0.0 1.6 8.0 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain Heme_oxygenase PF01126.20 ORY02253.1 - 6.9e-193 636.7 4.3 5.5e-64 215.7 0.0 3.1 3 0 0 3 3 3 3 Heme oxygenase Glyoxalase_2 PF12681.7 ORY02253.1 - 0.006 16.5 2.5 6.7 6.7 0.1 4.2 4 0 0 4 4 4 2 Glyoxalase-like domain AbrB-like PF14250.6 ORY02253.1 - 0.048 13.7 0.1 20 5.3 0.0 3.3 3 0 0 3 3 3 0 AbrB-like transcriptional regulator Inv-AAD PF18785.1 ORY02253.1 - 0.052 13.4 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase TENA_THI-4 PF03070.16 ORY02253.1 - 0.23 11.2 4.6 10 5.9 0.0 4.7 6 0 0 6 6 6 0 TENA/THI-4/PQQC family Hormone_2 PF00123.20 ORY02253.1 - 0.32 10.9 3.5 82 3.2 0.1 3.7 3 0 0 3 3 3 0 Peptide hormone DUF1372 PF07116.11 ORY02253.1 - 1.2 9.4 2.7 1.2e+02 2.9 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1372) HATPase_c PF02518.26 ORY02254.1 - 7.6e-27 94.0 0.5 1.6e-26 93.0 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY02254.1 - 1.5e-26 92.8 0.3 3.4e-26 91.6 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY02254.1 - 1.3e-20 73.2 0.3 3.8e-20 71.7 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 ORY02254.1 - 1.7e-06 28.7 0.0 5.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 ORY02254.1 - 3.1e-05 24.3 0.0 0.00037 20.8 0.0 2.5 3 0 0 3 3 3 1 GAF domain HATPase_c_3 PF13589.6 ORY02254.1 - 0.0002 21.2 0.1 0.00039 20.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 ORY02254.1 - 0.024 15.0 0.0 0.061 13.7 0.0 1.7 2 0 0 2 2 2 0 GAF domain ADH_N PF08240.12 ORY02309.1 - 2.3e-23 82.2 0.8 2.3e-23 82.2 0.8 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY02309.1 - 1.1e-15 57.7 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY02309.1 - 1.4e-05 24.5 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY02309.1 - 3.6e-05 24.8 0.0 7.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY02309.1 - 7.9e-05 22.1 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORY02309.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase EIF_2_alpha PF07541.12 ORY02309.1 - 0.11 12.6 0.0 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit 3HCDH_N PF02737.18 ORY02309.1 - 0.17 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kazal_1 PF00050.21 ORY02309.1 - 0.2 11.7 1.9 2.3 8.3 0.7 2.4 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain LPMO_10 PF03067.15 ORY02311.1 - 5.1e-06 27.3 0.0 5.3e-05 24.0 0.0 2.3 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY02311.1 - 0.00019 21.4 0.0 0.0036 17.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Hydrolase_4 PF12146.8 ORY02312.1 - 0.00095 18.5 0.2 0.23 10.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY02312.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY02312.1 - 0.044 13.4 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 ORY02312.1 - 0.16 11.5 0.0 0.43 10.1 0.0 1.8 2 1 0 2 2 2 0 Dienelactone hydrolase family GPI-anchored PF10342.9 ORY02313.1 - 0.0034 18.1 0.0 0.0048 17.6 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ABC_membrane PF00664.23 ORY02314.1 - 8.6e-58 196.2 25.2 1.6e-33 116.6 14.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY02314.1 - 1.7e-47 161.3 0.0 2.4e-26 92.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY02314.1 - 5e-08 32.6 1.5 0.43 10.0 0.2 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY02314.1 - 2.7e-05 24.5 0.1 0.37 11.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY02314.1 - 0.00011 22.1 0.1 0.094 12.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY02314.1 - 0.00012 22.5 0.0 0.6 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY02314.1 - 0.00022 21.3 0.2 0.019 15.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY02314.1 - 0.00087 19.2 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY02314.1 - 0.00095 18.9 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY02314.1 - 0.0031 18.0 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY02314.1 - 0.0036 17.1 0.0 2.4 7.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY02314.1 - 0.0047 16.7 0.6 3.5 7.3 0.0 3.4 4 0 0 4 4 3 1 IstB-like ATP binding protein TsaE PF02367.17 ORY02314.1 - 0.005 16.8 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 ORY02314.1 - 0.0096 15.0 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORY02314.1 - 0.015 14.8 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 ORY02314.1 - 0.027 13.4 0.0 4.9 6.0 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain DUF87 PF01935.17 ORY02314.1 - 0.028 14.5 0.1 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 ORY02314.1 - 0.07 13.2 1.1 0.99 9.4 0.3 2.3 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 ORY02314.1 - 0.071 13.5 0.1 0.87 10.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ORY02314.1 - 0.075 12.8 0.1 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 ORY02314.1 - 0.08 13.2 0.1 7.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 ORY02314.1 - 0.082 11.9 0.0 0.44 9.5 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ORY02314.1 - 0.087 12.4 0.7 4.2 6.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORY02314.1 - 0.11 11.7 0.6 13 4.9 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain AAA_18 PF13238.6 ORY02314.1 - 0.13 12.8 0.0 32 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY02314.1 - 0.16 11.9 0.2 17 5.3 0.0 3.0 3 0 0 3 3 2 0 NACHT domain DEAD PF00270.29 ORY02314.1 - 0.21 11.3 0.2 2.2 8.0 0.2 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase FKBP_C PF00254.28 ORY02315.1 - 1.5e-10 41.3 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Na_H_Exchanger PF00999.21 ORY02316.1 - 2.6e-69 233.8 38.3 3.2e-69 233.5 38.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LYRIC PF15686.5 ORY02316.1 - 0.052 13.1 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family SPT6_acidic PF14632.6 ORY02316.1 - 0.11 13.1 8.6 0.19 12.3 8.6 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Glyco_transf_49 PF13896.6 ORY02317.1 - 1.7e-26 93.3 0.2 2.6e-17 63.2 0.0 3.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PYRIN PF02758.16 ORY02317.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Na_H_Exchanger PF00999.21 ORY02318.1 - 2.2e-68 230.8 35.6 2.5e-68 230.6 35.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 ORY02318.1 - 0.45 10.4 4.6 0.25 11.2 0.8 2.2 2 0 0 2 2 2 0 Myc target protein 1 PAP2 PF01569.21 ORY02318.1 - 6.2 6.6 13.6 0.25 11.1 0.7 4.2 5 2 1 6 6 6 0 PAP2 superfamily PRK PF00485.18 ORY02319.1 - 2.1e-33 115.8 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 ORY02319.1 - 7.3e-05 22.1 0.0 0.00021 20.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 ORY02319.1 - 0.0034 17.9 0.1 0.01 16.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY02319.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ORY02319.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ORY02319.1 - 0.023 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain CoaE PF01121.20 ORY02319.1 - 0.077 12.7 0.2 1.9 8.2 0.0 2.5 3 0 0 3 3 3 0 Dephospho-CoA kinase ABC_tran PF00005.27 ORY02319.1 - 0.088 13.3 0.0 0.26 11.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 ORY02319.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ORY02319.1 - 0.18 11.6 0.1 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DDOST_48kD PF03345.14 ORY02320.1 - 5.1e-142 473.6 1.7 6.2e-142 473.3 1.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PLDc PF00614.22 ORY02320.1 - 0.25 11.6 1.4 2.3 8.6 0.4 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif SAGA-Tad1 PF12767.7 ORY02321.1 - 1.9e-52 178.4 0.0 2.7e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 ORY02321.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family ATP_transf PF09830.9 ORY02322.1 - 4.6e-19 68.3 0.1 1.2e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.23 ORY02322.1 - 1.2e-05 25.9 0.0 3.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 HIT domain DUF4931 PF16285.5 ORY02322.1 - 0.029 13.7 0.1 0.058 12.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) FMN_dh PF01070.18 ORY02323.1 - 1.2e-123 412.6 0.0 1.4e-123 412.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY02323.1 - 1.8e-24 85.7 0.0 4.4e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORY02323.1 - 4.3e-05 22.8 0.0 7.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY02323.1 - 5.8e-05 22.3 0.1 9.4e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 ORY02323.1 - 0.00023 20.7 0.0 0.12 11.8 0.0 2.8 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 ORY02323.1 - 0.097 12.0 0.1 8.4 5.6 0.0 2.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG COG5 PF10392.9 ORY02324.1 - 0.019 15.1 1.5 0.032 14.4 0.4 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 TPD52 PF04201.15 ORY02324.1 - 0.052 13.2 5.7 0.027 14.1 2.5 1.9 1 1 1 2 2 2 0 Tumour protein D52 family DUF1793 PF08760.11 ORY02324.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) Exonuc_VII_L PF02601.15 ORY02324.1 - 0.26 10.8 1.3 0.31 10.5 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ras PF00071.22 ORY02325.1 - 1.1e-46 158.3 0.5 1.3e-46 158.2 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY02325.1 - 2.6e-15 56.7 0.1 4e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY02325.1 - 8.2e-09 35.2 0.1 8.8e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY02325.1 - 1.4e-06 28.0 0.1 9.3e-06 25.3 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORY02325.1 - 0.00014 21.4 0.1 0.0021 17.6 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY02325.1 - 0.00022 21.1 0.0 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 ORY02325.1 - 0.00084 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY02325.1 - 0.00093 19.3 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORY02325.1 - 0.014 15.4 0.1 0.027 14.5 0.0 1.6 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 ORY02325.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 ORY02326.1 - 1.9e-100 335.4 0.8 2.2e-100 335.1 0.8 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY02326.1 - 1.7e-13 50.8 0.0 2.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY02326.1 - 1.9e-09 37.7 1.6 2.9e-08 33.8 0.5 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 ORY02326.1 - 8e-08 32.1 0.1 0.0015 18.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 ORY02326.1 - 2.7e-07 30.2 0.0 3.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 ORY02326.1 - 9.5e-05 21.7 1.4 0.002 17.3 0.7 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 ORY02326.1 - 0.0099 15.5 0.6 0.025 14.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain PhnA_Zn_Ribbon PF08274.12 ORY02326.1 - 0.11 12.5 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon VirC1 PF07015.11 ORY02326.1 - 0.18 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein DUF3245 PF11595.8 ORY02327.1 - 1.1e-06 29.2 0.2 1.1e-06 29.2 0.2 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3245) NOP19 PF10863.8 ORY02327.1 - 0.19 11.5 7.5 0.16 11.8 3.7 2.5 1 1 1 2 2 2 0 Nucleolar protein 19 PGA2 PF07543.12 ORY02327.1 - 1 9.3 13.0 2.6 8.1 5.9 2.3 1 1 1 2 2 2 0 Protein trafficking PGA2 zf-RING_4 PF14570.6 ORY02328.1 - 2.4e-22 78.5 12.6 4.9e-22 77.5 12.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY02328.1 - 1e-08 34.9 8.3 1e-08 34.9 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 ORY02328.1 - 3e-07 30.2 0.0 3.3e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 ORY02328.1 - 0.00013 21.7 9.7 0.019 14.8 10.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 ORY02328.1 - 0.0012 18.8 5.2 0.0012 18.8 5.2 1.8 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 ORY02328.1 - 0.002 18.4 12.2 0.002 18.4 12.2 1.7 2 0 0 2 2 2 1 Ring finger domain Rtf2 PF04641.12 ORY02328.1 - 0.0027 17.1 1.3 0.0033 16.8 1.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Nup35_RRM PF05172.13 ORY02328.1 - 0.0096 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-UDP PF14569.6 ORY02328.1 - 0.014 15.5 4.2 0.027 14.6 4.2 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 ORY02328.1 - 0.018 14.9 12.1 0.037 13.9 12.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 ORY02328.1 - 0.037 14.7 0.5 0.078 13.7 0.1 1.8 2 0 0 2 2 2 0 Torus domain Rad50_zn_hook PF04423.14 ORY02328.1 - 0.038 13.8 2.4 2.5 8.0 0.2 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1154 PF06631.11 ORY02328.1 - 0.072 13.1 1.7 0.13 12.3 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Nup35_RRM_2 PF14605.6 ORY02328.1 - 0.12 12.4 0.3 0.33 11.0 0.1 1.9 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-RING_UBOX PF13445.6 ORY02328.1 - 0.12 12.4 9.0 0.14 12.2 6.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY02328.1 - 0.12 12.2 12.4 0.3 11.0 12.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 ORY02328.1 - 2.4 8.4 9.2 0.52 10.5 4.1 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Hamartin PF04388.12 ORY02329.1 - 3.5 6.2 11.7 4.4 5.8 11.7 1.2 1 0 0 1 1 1 0 Hamartin protein TrmO_C PF18389.1 ORY02330.1 - 0.056 13.5 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 TrmO C-terminal domain PRELI PF04707.14 ORY02331.1 - 7.1e-45 152.6 0.0 8e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family NAC PF01849.18 ORY02332.1 - 2.7e-21 75.3 0.1 1.8e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 NAC domain NSP2-B_epitope PF14757.6 ORY02332.1 - 0.02 14.6 0.4 0.02 14.6 0.4 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein MscS_TM PF12794.7 ORY02332.1 - 1.6 7.6 4.3 1.8 7.3 4.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FAD_binding_6 PF00970.24 ORY02333.1 - 2.1e-34 117.8 0.0 3.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY02333.1 - 5.9e-34 117.0 0.0 1e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY02333.1 - 1.4e-08 35.0 0.2 3.1e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORY02333.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SNARE PF05739.19 ORY02334.1 - 3.6e-12 46.1 0.2 3.6e-12 46.1 0.2 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 ORY02334.1 - 4.8e-05 23.1 8.8 0.00043 20.0 8.8 2.2 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 ORY02334.1 - 0.0017 18.2 4.4 0.02 14.7 0.4 2.8 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 ORY02334.1 - 0.0097 16.3 10.8 0.14 12.5 5.9 2.7 2 1 1 3 3 3 1 Syntaxin-like protein DUF948 PF06103.11 ORY02334.1 - 0.084 13.1 1.6 19 5.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF885 PF05960.11 ORY02334.1 - 0.22 11.1 1.5 0.57 9.8 1.4 1.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF885) RNase_J_C PF17770.1 ORY02334.1 - 0.44 11.6 3.2 0.9 10.6 0.2 2.9 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain Transcrip_act PF04949.13 ORY02334.1 - 1.5 8.7 7.6 0.18 11.7 0.8 2.6 1 1 0 3 3 3 0 Transcriptional activator CCDC-167 PF15188.6 ORY02334.1 - 8.3 6.8 12.2 5 7.5 1.2 3.7 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 GDPD PF03009.17 ORY02335.1 - 0.016 15.0 0.1 0.055 13.2 0.1 1.8 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family O-FucT PF10250.9 ORY02338.1 - 2e-16 60.7 0.1 8.5e-16 58.6 0.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ccdc124 PF06244.12 ORY02339.1 - 2.2e-30 105.9 19.5 5.1e-30 104.7 19.5 1.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORY02339.1 - 0.0079 16.6 0.5 0.0079 16.6 0.5 2.1 2 1 0 2 2 2 1 HMG (high mobility group) box Abhydrolase_6 PF12697.7 ORY02340.1 - 3.8e-16 60.4 0.0 4.5e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY02340.1 - 6.7e-13 48.5 0.0 2.3e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY02340.1 - 3.5e-10 40.0 0.0 2.6e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY02340.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY02340.1 - 0.003 17.1 0.0 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 ORY02340.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TPP_enzyme_M PF00205.22 ORY02340.1 - 0.039 13.7 0.0 0.09 12.5 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Peptidase_S15 PF02129.18 ORY02340.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MAP1B_neuraxin PF00414.17 ORY02340.1 - 0.081 12.5 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat BLM10_mid PF16507.5 ORY02341.1 - 1.6e-128 429.6 7.6 1.4e-127 426.6 7.6 2.2 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 ORY02341.1 - 4e-27 94.0 0.0 4.2e-26 90.7 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 ORY02341.1 - 0.0018 18.4 0.3 5.1 7.6 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat RPAP3_C PF13877.6 ORY02341.1 - 0.15 12.6 0.7 3.2 8.4 0.0 3.7 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 TAF6_C PF07571.13 ORY02341.1 - 0.16 12.3 0.3 5.5 7.4 0.1 3.3 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Aminotran_1_2 PF00155.21 ORY02342.1 - 2.3e-47 161.9 0.0 2.5e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY02342.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Amidohydro_1 PF01979.20 ORY02391.1 - 2e-72 244.4 1.8 3.9e-72 243.4 1.8 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY02391.1 - 3.6e-56 188.7 2.9 8.5e-56 187.5 2.9 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORY02391.1 - 3.2e-38 129.7 0.0 6.2e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 ORY02391.1 - 1.2e-37 128.2 0.1 2.4e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORY02391.1 - 6e-06 26.0 0.1 2.8e-05 23.8 0.0 1.9 1 1 0 2 2 2 1 Amidohydrolase family Tipalpha PF16753.5 ORY02392.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter ECH_1 PF00378.20 ORY02393.1 - 1.5e-35 122.7 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY02393.1 - 1.1e-18 67.9 0.2 4.6e-18 65.8 0.2 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY02393.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 Whi5 PF08528.11 ORY02393.1 - 0.16 11.6 0.3 0.39 10.4 0.3 1.7 1 0 0 1 1 1 0 Whi5 like PAP2 PF01569.21 ORY02394.1 - 6.4e-32 110.2 2.0 6.4e-32 110.2 2.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.16 ORY02394.1 - 0.00099 19.1 1.8 0.087 12.8 1.9 2.6 2 1 0 2 2 2 1 Colicin V production protein DUF5510 PF17629.2 ORY02394.1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5510) TMEM154 PF15102.6 ORY02394.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4153 PF13687.6 ORY02394.1 - 0.11 12.1 4.2 0.36 10.4 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) PAP2_3 PF14378.6 ORY02394.1 - 0.23 11.1 9.8 0.28 10.9 7.0 2.4 1 1 0 1 1 1 0 PAP2 superfamily Strabismus PF06638.11 ORY02394.1 - 0.26 9.9 0.3 0.39 9.3 0.3 1.2 1 0 0 1 1 1 0 Strabismus protein Glyco_hydro_18 PF00704.28 ORY02396.1 - 3.6e-28 99.2 4.9 1.5e-27 97.2 4.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Clat_adaptor_s PF01217.20 ORY02397.1 - 1.3e-20 73.8 0.1 1.6e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_18 PF13238.6 ORY02397.1 - 0.033 14.7 0.0 0.25 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sda PF08970.10 ORY02397.1 - 0.05 13.4 0.1 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Sporulation inhibitor A Thymidylate_kin PF02223.17 ORY02397.1 - 0.075 12.7 0.2 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AP-5_subunit_s1 PF15001.6 ORY02397.1 - 0.11 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 GPI-anchored PF10342.9 ORY02398.1 - 5.7e-11 43.0 0.0 7.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TRAM_LAG1_CLN8 PF03798.16 ORY02399.1 - 2.8e-37 128.4 17.1 3.7e-37 128.0 17.1 1.1 1 0 0 1 1 1 1 TLC domain Peptidase_C13 PF01650.18 ORY02400.1 - 5e-48 163.9 0.0 5.8e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 ORY02400.1 - 0.0046 17.2 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute RasGAP PF00616.19 ORY02401.1 - 1.6e-60 204.4 0.1 5e-60 202.8 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY02401.1 - 2.9e-33 114.9 0.5 7.5e-32 110.3 0.0 2.6 2 0 0 2 2 2 1 RasGAP C-terminus DUF4047 PF13256.6 ORY02401.1 - 0.02 15.1 0.1 0.053 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) YabA PF06156.13 ORY02401.1 - 0.08 13.6 5.5 4.8 7.9 0.5 2.8 2 0 0 2 2 2 0 Initiation control protein YabA HR1 PF02185.16 ORY02401.1 - 0.86 9.8 4.8 2.1 8.5 1.0 2.7 2 0 0 2 2 2 0 Hr1 repeat CASP_C PF08172.12 ORY02401.1 - 0.91 8.8 4.9 0.11 11.8 0.6 1.6 2 0 0 2 2 2 0 CASP C terminal FlaC_arch PF05377.11 ORY02401.1 - 1.2 9.6 3.9 0.72 10.3 0.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 ORY02401.1 - 2.2 8.3 8.7 3.2 7.8 0.9 3.3 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding CAP PF00188.26 ORY02402.1 - 2.7e-11 44.4 0.1 3.8e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GPI-anchored PF10342.9 ORY02403.1 - 2.5e-10 41.0 0.4 2.5e-10 41.0 0.4 3.4 2 1 2 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 7kD_DNA_binding PF02294.18 ORY02403.1 - 0.21 11.7 0.9 0.63 10.1 0.2 2.1 2 0 0 2 2 2 0 7kD DNA-binding domain FAM196 PF15265.6 ORY02403.1 - 7.6 5.9 23.1 9.7 5.6 23.1 1.1 1 0 0 1 1 1 0 FAM196 family UQ_con PF00179.26 ORY02404.1 - 2.1e-49 166.8 0.0 2.3e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY02404.1 - 0.18 12.1 1.2 0.47 10.7 1.2 1.9 1 1 0 1 1 1 0 RWD domain Myb_DNA-binding PF00249.31 ORY02405.1 - 6.6e-57 189.5 19.8 7.4e-13 48.5 0.3 5.2 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY02405.1 - 2.2e-50 168.7 10.7 1e-14 54.5 0.4 5.1 2 2 3 5 5 5 5 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY02405.1 - 5.9e-11 42.4 10.6 0.00095 19.3 0.1 5.5 2 1 4 6 6 6 3 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 ORY02405.1 - 2.1e-09 37.1 0.6 0.052 13.4 0.2 4.3 2 1 2 4 4 4 2 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 ORY02405.1 - 9.2e-06 25.7 5.5 7.7 6.7 0.1 5.5 5 0 0 5 5 5 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 ORY02405.1 - 0.00067 19.7 1.0 0.019 15.0 0.1 3.1 3 1 1 4 4 4 1 SLIDE Rap1_C PF11626.8 ORY02405.1 - 0.0061 16.6 0.0 8.8 6.5 0.0 3.3 2 1 1 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ExsD PF16806.5 ORY02405.1 - 0.014 15.3 2.0 2.3 8.1 0.5 2.2 2 0 0 2 2 2 0 Antiactivator protein ExsD Myb_DNA-bind_4 PF13837.6 ORY02405.1 - 0.075 13.4 17.6 9.6 6.7 0.1 5.9 4 3 1 5 5 5 0 Myb/SANT-like DNA-binding domain DUF4599 PF15371.6 ORY02405.1 - 0.1 13.1 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) TMEM171 PF15471.6 ORY02405.1 - 0.23 10.4 0.4 0.31 10.0 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 TryThrA_C PF12319.8 ORY02405.1 - 0.47 9.9 7.1 3.3 7.1 7.1 2.1 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal QWRF PF04484.12 ORY02406.1 - 7.9e-15 55.4 10.3 1.9e-14 54.1 10.3 1.7 1 1 0 1 1 1 1 QWRF family THOC7 PF05615.13 ORY02406.1 - 0.056 13.7 9.5 0.053 13.8 3.2 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 DUF2408 PF10303.9 ORY02406.1 - 0.14 12.7 6.3 8.6 6.9 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 ORY02406.1 - 0.4 11.1 6.0 4.5 7.8 0.5 2.8 2 2 1 3 3 3 0 Snapin/Pallidin SLED PF12140.8 ORY02406.1 - 0.69 10.5 3.0 12 6.4 0.1 2.4 2 0 0 2 2 2 0 SLED domain DUF724 PF05266.14 ORY02406.1 - 0.83 9.4 9.8 3.4 7.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tex_N PF09371.10 ORY02406.1 - 0.87 9.2 6.0 0.35 10.5 1.1 2.2 2 0 0 2 2 2 0 Tex-like protein N-terminal domain GCN5L1 PF06320.13 ORY02406.1 - 0.87 9.7 8.2 7.4 6.8 0.4 2.8 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF948 PF06103.11 ORY02406.1 - 1.2 9.5 4.1 9.7 6.5 2.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SH3BP5 PF05276.14 ORY02406.1 - 1.9 8.2 14.1 1.1 9.1 4.2 2.7 2 1 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) BLOC1_2 PF10046.9 ORY02406.1 - 2 8.7 9.5 0.56 10.5 1.2 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.9 ORY02406.1 - 2 8.4 8.8 5.2 7.1 0.7 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Syntaxin_2 PF14523.6 ORY02406.1 - 2.3 8.6 8.1 1.5 9.3 2.0 2.6 1 1 1 2 2 2 0 Syntaxin-like protein DHR10 PF18595.1 ORY02406.1 - 5.1 7.2 14.0 1.3 9.1 0.9 3.4 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 ORY02406.1 - 5.2 7.1 14.6 3.8 7.5 2.2 3.3 2 1 1 3 3 3 0 Prefoldin subunit GPI-anchored PF10342.9 ORY02407.1 - 5.1e-12 46.4 0.4 1e-11 45.4 0.4 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bestrophin PF01062.21 ORY02408.1 - 4.9e-42 144.3 0.2 6.4e-42 144.0 0.2 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Cyclin_N PF00134.23 ORY02409.1 - 3.7e-14 52.6 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY02409.1 - 4.3e-07 30.5 0.1 5.7e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin Histone_H2A_C PF16211.5 ORY02411.1 - 4.6e-20 71.1 2.3 8.3e-20 70.2 2.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY02411.1 - 1.8e-16 60.7 0.0 2.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY02411.1 - 2.8e-05 24.3 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clat_adaptor_s PF01217.20 ORY02412.1 - 2.8e-57 192.6 3.1 3.1e-57 192.5 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 ORY02412.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Thiolase_N PF00108.23 ORY02413.1 - 4.4e-85 285.2 5.4 6.7e-85 284.6 4.3 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY02413.1 - 1.3e-46 157.2 0.4 3.7e-46 155.8 0.4 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORY02413.1 - 0.027 14.3 0.1 9 6.2 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 ORY02413.1 - 0.06 13.5 0.0 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 ORY02413.1 - 0.08 12.5 4.1 0.19 11.3 1.6 2.5 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain DUF2180 PF09947.9 ORY02413.1 - 0.18 11.8 0.7 0.37 10.8 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Aldo_ket_red PF00248.21 ORY02414.1 - 6.8e-72 242.1 0.0 7.7e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Paf1 PF03985.13 ORY02415.1 - 5.1e-80 269.5 2.9 5.7e-80 269.4 2.9 1.0 1 0 0 1 1 1 1 Paf1 Histone_H2A_C PF16211.5 ORY02416.1 - 4.6e-20 71.1 2.3 8.3e-20 70.2 2.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY02416.1 - 1.8e-16 60.7 0.0 2.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY02416.1 - 2.8e-05 24.3 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ_C PF01556.18 ORY02417.1 - 4.5e-37 127.4 0.0 6.1e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY02417.1 - 6.2e-26 90.3 4.3 1.1e-25 89.5 4.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY02417.1 - 5.2e-11 42.8 11.4 9e-11 42.0 11.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY02417.1 - 0.0063 16.4 2.1 0.0063 16.4 2.1 3.1 2 1 1 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2318 PF10080.9 ORY02417.1 - 0.065 13.4 1.2 0.098 12.8 0.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) HypA PF01155.19 ORY02417.1 - 1.4 9.0 3.7 5.6 7.0 3.7 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 ORY02417.1 - 3.2 7.9 6.3 0.6 10.3 2.0 2.0 2 0 0 2 2 2 0 Zinc ribbon domain 5_nucleotid_C PF02872.18 ORY02418.1 - 1.3e-37 129.5 0.0 2.4e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORY02418.1 - 7.4e-11 42.9 0.5 1.3e-10 42.1 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATG101 PF07855.12 ORY02418.1 - 0.032 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 101 DUF1794 PF08768.11 ORY02419.1 - 7.6e-35 120.1 0.1 8.5e-35 119.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) MFS_1 PF07690.16 ORY02420.1 - 1.2e-17 63.9 20.8 2.5e-11 43.1 5.2 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily zf-CCCH PF00642.24 ORY02421.1 - 9.1e-20 70.1 14.1 8.9e-14 51.0 1.9 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY02421.1 - 5.5e-13 48.5 13.1 2.3e-08 33.8 2.9 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 ORY02421.1 - 2.7e-10 39.8 12.3 8.5e-06 25.4 0.8 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORY02421.1 - 0.0013 19.4 10.5 0.07 13.8 2.4 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 ORY02421.1 - 0.0023 18.4 0.5 0.0023 18.4 0.5 2.6 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger CLIP_SPH_mas PF18398.1 ORY02421.1 - 0.018 15.4 0.8 0.018 15.4 0.8 2.1 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade Defensin_int PF17858.1 ORY02421.1 - 0.072 13.1 2.8 0.16 12.0 1.0 2.0 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-CCHH PF10283.9 ORY02421.1 - 1.7 8.7 11.8 2.7 8.1 0.8 2.9 3 0 0 3 3 3 0 PBZ domain oligo_HPY PF08352.12 ORY02421.1 - 3.4 8.3 9.2 6.8 7.3 1.6 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Hexokinase_2 PF03727.16 ORY02422.1 - 4e-73 245.8 0.0 5.1e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY02422.1 - 3.5e-61 206.6 0.0 4.9e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Pkinase PF00069.25 ORY02423.1 - 2.8e-49 167.9 0.0 5.3e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02423.1 - 4.7e-20 72.0 0.0 6.5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY02423.1 - 2.5e-05 23.8 0.4 4.3e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY02423.1 - 0.00027 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY02423.1 - 0.00074 19.5 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY02423.1 - 0.00083 19.0 0.4 0.021 14.4 0.1 2.4 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY02423.1 - 0.0011 17.9 0.2 0.0011 17.9 0.2 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY02423.1 - 0.029 13.2 0.4 0.035 12.9 0.4 1.3 1 1 0 1 1 1 0 Fungal protein kinase Rieske PF00355.26 ORY02423.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.6 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain PIP49_C PF12260.8 ORY02423.1 - 0.049 13.3 0.1 0.098 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 AAA PF00004.29 ORY02424.1 - 2.8e-43 147.5 0.0 4.7e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY02424.1 - 6.6e-14 51.4 0.1 1.4e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORY02424.1 - 2.1e-11 43.6 0.6 6e-11 42.1 0.0 2.1 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 ORY02424.1 - 1.3e-07 32.2 0.0 7.1e-05 23.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORY02424.1 - 7.2e-07 29.3 0.1 1.9e-05 24.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY02424.1 - 3e-06 27.5 0.0 8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY02424.1 - 6.5e-06 26.0 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY02424.1 - 0.00022 21.5 0.1 0.0066 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY02424.1 - 0.00073 20.1 0.0 0.0026 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY02424.1 - 0.00076 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY02424.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 ORY02424.1 - 0.0021 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY02424.1 - 0.0033 16.9 0.0 0.0089 15.4 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY02424.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ORY02424.1 - 0.0053 16.8 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORY02424.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY02424.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 ORY02424.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY02424.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Prot_ATP_OB_N PF17758.1 ORY02424.1 - 0.0091 15.6 0.1 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_3 PF07726.11 ORY02424.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORY02424.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY02424.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY02424.1 - 0.056 13.2 0.8 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY02424.1 - 0.059 12.7 0.8 0.17 11.2 0.0 2.1 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 ORY02424.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 ORY02424.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 ORY02424.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ORY02424.1 - 0.081 12.6 0.1 3.7 7.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_25 PF13481.6 ORY02424.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY02424.1 - 0.13 11.6 0.3 0.26 10.5 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin Parvo_NS1 PF01057.17 ORY02424.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Clathrin PF00637.20 ORY02425.1 - 8.4e-206 674.1 49.4 1.3e-34 119.1 1.9 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 ORY02425.1 - 1.5e-42 141.8 1.7 8e-07 29.1 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 ORY02425.1 - 1.9e-31 107.7 0.1 9.6e-31 105.5 0.1 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 ORY02425.1 - 1.4e-13 49.9 1.1 3.8e-13 48.5 1.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 ORY02425.1 - 0.00014 21.0 4.9 0.15 11.1 0.0 4.7 5 0 0 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.28 ORY02425.1 - 0.00052 19.7 1.0 9.5 6.2 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02425.1 - 0.0023 18.6 3.1 30 5.8 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02425.1 - 0.0084 16.2 3.7 40 4.7 0.1 5.8 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY02425.1 - 0.011 15.8 1.6 10 6.4 0.1 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02425.1 - 0.036 14.3 0.6 29 5.0 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02425.1 - 0.31 11.4 5.8 13 6.3 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TED_complement PF07678.14 ORY02426.1 - 0.075 12.0 0.0 0.077 12.0 0.0 1.0 1 0 0 1 1 1 0 A-macroglobulin TED domain Chitin_synth_2 PF03142.15 ORY02427.1 - 7.6e-238 790.4 1.9 1.1e-237 789.9 1.9 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY02427.1 - 4.8e-145 484.4 7.0 6.6e-145 484.0 7.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY02427.1 - 1.2e-17 63.5 0.1 5.3e-17 61.5 0.3 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORY02427.1 - 6.5e-12 45.8 0.0 2.6e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY02427.1 - 1.9e-10 41.0 0.5 1.9e-10 41.0 0.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 ORY02427.1 - 1e-08 35.2 0.2 0.0037 17.4 0.1 3.8 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY02427.1 - 0.00051 19.9 0.0 0.097 12.5 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY02427.1 - 0.074 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 SET PF00856.28 ORY02428.1 - 2.3e-22 80.1 1.3 8e-21 75.2 1.3 2.2 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 ORY02428.1 - 0.05 13.7 0.3 0.077 13.1 0.3 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N DUF4176 PF13780.6 ORY02428.1 - 0.18 11.9 0.4 0.47 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) RRM_1 PF00076.22 ORY02429.1 - 3.9e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SBE2 PF17076.5 ORY02429.1 - 0.025 12.8 1.2 0.031 12.5 1.2 1.0 1 0 0 1 1 1 0 SBE2, cell-wall formation Ribosomal_S8 PF00410.19 ORY02430.1 - 2.8e-19 69.3 0.0 1.5e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_6 PF00970.24 ORY02430.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF3395 PF11875.8 ORY02431.1 - 6.1e-37 126.9 1.2 6.1e-37 126.9 1.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 ORY02431.1 - 1.3e-22 79.7 0.4 3.1e-22 78.5 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain CFAP91 PF14738.6 ORY02431.1 - 3.7 7.6 9.5 0.52 10.4 1.8 2.8 3 0 0 3 3 3 0 Cilia- and flagella-associated protein 91 Tmemb_14 PF03647.13 ORY02432.1 - 1.6e-28 99.3 13.0 1.8e-28 99.1 13.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CPP1-like PF11833.8 ORY02432.1 - 0.04 13.6 5.0 0.051 13.2 5.0 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like VSP PF03302.13 ORY02432.1 - 0.32 9.8 0.7 0.45 9.3 0.7 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Tmemb_170 PF10190.9 ORY02434.1 - 1.1e-22 80.4 16.4 1.2e-22 80.2 16.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1129 PF06570.11 ORY02434.1 - 0.94 8.9 7.3 1.1 8.8 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Iso_dh PF00180.20 ORY02435.1 - 4e-79 266.3 0.0 5e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DnaJ PF00226.31 ORY02436.1 - 2.6e-14 53.1 0.0 4.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain YrhC PF14143.6 ORY02436.1 - 0.018 15.1 3.2 0.051 13.7 0.2 2.3 2 0 0 2 2 2 0 YrhC-like protein ArfGap PF01412.18 ORY02437.1 - 2.1e-38 131.0 2.0 3.2e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 ORY02437.1 - 5.4e-12 46.1 1.3 7.2e-12 45.7 0.4 1.8 2 0 0 2 2 2 1 PH domain CBM_5_12_2 PF14600.6 ORY02490.1 - 0.0036 17.2 1.9 0.0048 16.8 1.9 1.4 1 1 0 1 1 1 1 Cellulose-binding domain CBM_5_12 PF02839.14 ORY02490.1 - 0.0055 17.2 1.6 0.0055 17.2 1.6 2.0 3 0 0 3 3 3 1 Carbohydrate binding domain CBM_5_12 PF02839.14 ORY02491.1 - 7.2e-07 29.4 20.5 0.00015 22.1 6.0 4.1 5 1 0 5 5 5 2 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORY02491.1 - 0.00079 19.3 18.5 0.028 14.3 1.9 3.7 3 1 0 3 3 3 2 Cellulose-binding domain DUF1509 PF07420.11 ORY02491.1 - 0.011 14.7 0.2 0.014 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MIP PF00230.20 ORY02492.1 - 1e-53 182.4 16.1 1.1e-53 182.3 16.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3522 PF12036.8 ORY02492.1 - 0.02 15.2 0.3 0.058 13.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) DUF3481 PF11980.8 ORY02492.1 - 0.021 14.5 1.5 0.043 13.5 1.5 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein RMI1_N PF08585.12 ORY02493.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein Cbl_N3 PF02762.14 ORY02493.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Retrotrans_gag PF03732.17 ORY02494.1 - 0.1 12.9 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Ribosomal_L10 PF00466.20 ORY02495.1 - 1e-24 86.6 0.7 1.4e-24 86.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORY02495.1 - 1.3e-21 76.4 0.0 1.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P tRNA-synt_1 PF00133.22 ORY02496.1 - 6.3e-180 599.4 0.2 6.3e-179 596.1 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY02496.1 - 1.5e-39 135.4 0.2 1.4e-38 132.2 0.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY02496.1 - 3e-14 52.6 2.6 1e-05 24.5 0.0 4.6 3 2 2 5 5 5 3 tRNA synthetases class I (M) TPR_1 PF00515.28 ORY02496.1 - 3.5e-12 45.6 7.6 5.3e-05 22.9 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02496.1 - 4.2e-11 42.1 5.2 0.00048 20.0 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY02496.1 - 1.6e-09 37.3 3.3 3e-05 23.6 0.1 3.6 3 0 0 3 3 3 2 TPR repeat Val_tRNA-synt_C PF10458.9 ORY02496.1 - 5.1e-07 29.9 2.0 1.3e-06 28.6 2.0 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 ORY02496.1 - 1.3e-06 28.0 0.0 2.5e-05 23.8 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 TPR_19 PF14559.6 ORY02496.1 - 1.3e-05 25.6 1.1 3e-05 24.5 0.3 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02496.1 - 1.4e-05 25.3 0.7 0.00019 21.6 0.4 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02496.1 - 4.1e-05 24.1 0.1 1 10.3 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02496.1 - 0.00011 22.1 5.1 0.71 10.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat tRNA-synt_1e PF01406.19 ORY02496.1 - 0.00013 21.4 0.0 0.005 16.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain TPR_9 PF13371.6 ORY02496.1 - 0.00015 21.9 1.5 0.013 15.6 1.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY02496.1 - 0.01 15.8 0.1 12 6.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY02496.1 - 0.063 13.9 0.3 0.28 11.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Fungal_TACC PF12709.7 ORY02496.1 - 0.073 13.5 0.1 8.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_17 PF13431.6 ORY02496.1 - 0.078 13.4 0.6 16 6.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DivIC PF04977.15 ORY02496.1 - 0.1 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Septum formation initiator Matrilin_ccoil PF10393.9 ORY02496.1 - 0.15 12.0 0.2 0.43 10.5 0.2 1.9 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin COG2 PF06148.11 ORY02496.1 - 0.17 12.0 2.1 0.45 10.6 0.3 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC-167 PF15188.6 ORY02496.1 - 1.2 9.5 3.8 2.3 8.6 1.6 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 V-SNARE PF05008.15 ORY02496.1 - 3.4 8.1 6.7 0.47 10.9 0.6 2.7 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus Plasmodium_HRP PF05403.11 ORY02497.1 - 2e-09 37.6 48.2 1.7e-05 24.7 34.7 3.0 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) CBM_19 PF03427.13 ORY02497.1 - 0.0017 18.3 6.7 0.0076 16.2 6.7 2.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORY02497.1 - 4.2 7.6 9.5 0.68 10.1 3.9 2.6 2 1 1 3 3 3 0 Chitin binding Peritrophin-A domain Plasmodium_HRP PF05403.11 ORY02498.1 - 1.2e-05 25.3 24.6 0.023 14.5 14.5 2.5 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) CBM_19 PF03427.13 ORY02498.1 - 0.012 15.6 6.7 0.036 14.0 6.7 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) CBM_19 PF03427.13 ORY02499.1 - 0.00011 22.2 11.6 0.00037 20.4 9.4 2.5 2 1 0 2 2 2 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORY02499.1 - 0.043 14.0 3.4 0.24 11.6 3.7 2.1 1 1 1 2 2 2 0 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 ORY02500.1 - 7.6e-07 29.0 7.0 1.3e-05 25.1 7.0 2.0 1 1 0 1 1 1 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORY02500.1 - 0.022 14.9 3.8 0.1 12.8 3.8 2.0 1 1 0 1 1 1 0 Chitin binding Peritrophin-A domain Med11 PF10280.9 ORY02501.1 - 5.6e-11 43.1 0.0 7.5e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 Mediator complex protein ACPS PF01648.20 ORY02502.1 - 7.7e-12 45.4 0.0 9.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Synaptobrevin PF00957.21 ORY02503.1 - 6.8e-28 96.3 2.2 8.2e-28 96.0 2.2 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 ORY02503.1 - 0.0055 16.8 0.4 0.0069 16.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter EMP24_GP25L PF01105.24 ORY02503.1 - 0.038 13.9 0.7 0.049 13.6 0.7 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tweety PF04906.13 ORY02503.1 - 0.047 12.3 0.1 0.051 12.2 0.1 1.0 1 0 0 1 1 1 0 Tweety GIT1_C PF12205.8 ORY02503.1 - 0.1 12.7 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF2937 PF11157.8 ORY02503.1 - 0.27 11.0 1.6 0.26 11.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) GDC-P PF02347.16 ORY02504.1 - 5e-206 684.6 4.3 9.9e-195 647.4 0.2 3.3 4 0 0 4 4 4 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ORY02504.1 - 7.2e-06 25.2 1.7 1.8e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY02504.1 - 0.00011 21.6 0.7 0.0017 17.7 0.0 2.7 3 0 0 3 3 3 1 Beta-eliminating lyase DUF1805 PF08827.11 ORY02504.1 - 0.014 15.7 0.0 0.061 13.7 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) SMC_N PF02463.19 ORY02505.1 - 3.9e-48 163.8 0.0 8.4e-48 162.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY02505.1 - 2.6e-27 95.4 0.3 1.6e-26 92.9 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY02505.1 - 1.2e-06 28.6 0.4 1.2e-06 28.6 0.4 2.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF812 PF05667.11 ORY02505.1 - 0.00034 19.6 17.2 0.00034 19.6 17.2 4.2 3 1 1 4 4 3 1 Protein of unknown function (DUF812) NPV_P10 PF05531.12 ORY02505.1 - 0.00067 20.1 0.0 0.00067 20.1 0.0 7.8 7 2 0 7 7 6 2 Nucleopolyhedrovirus P10 protein Bap31_Bap29_C PF18035.1 ORY02505.1 - 0.00086 19.3 0.6 0.00086 19.3 0.6 6.5 8 1 0 8 8 6 1 Bap31/Bap29 cytoplasmic coiled-coil domain Spc7 PF08317.11 ORY02505.1 - 0.001 18.1 6.1 0.001 18.1 6.1 7.1 3 2 3 7 7 6 2 Spc7 kinetochore protein SbcCD_C PF13558.6 ORY02505.1 - 0.0029 17.8 0.0 0.016 15.4 0.0 2.3 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit UPF0242 PF06785.11 ORY02505.1 - 0.0038 17.4 19.7 0.0038 17.4 19.7 7.9 5 1 3 8 8 8 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 ORY02505.1 - 0.01 16.1 1.8 0.01 16.1 1.8 7.4 4 3 3 7 7 6 0 Autophagy protein 16 (ATG16) Laminin_I PF06008.14 ORY02505.1 - 0.012 15.4 1.7 0.012 15.4 1.7 6.5 3 2 1 5 5 4 0 Laminin Domain I DUF1482 PF07358.11 ORY02505.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) XhlA PF10779.9 ORY02505.1 - 0.047 13.9 0.2 0.047 13.9 0.2 9.3 7 2 3 10 10 9 0 Haemolysin XhlA DUF1664 PF07889.12 ORY02505.1 - 0.067 13.2 0.1 0.067 13.2 0.1 8.8 4 4 2 8 8 8 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORY02505.1 - 0.081 13.2 20.9 3.9 7.8 1.8 6.3 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 ORY02505.1 - 0.1 13.0 0.1 0.1 13.0 0.1 9.5 8 2 2 10 10 9 0 Flagella accessory protein C (FlaC) Acyl-CoA_dh_2 PF08028.11 ORY02505.1 - 5.2 7.4 8.0 5.4 7.3 0.5 3.5 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_11 PF08241.12 ORY02506.1 - 2.5e-22 79.3 0.0 4.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02506.1 - 9.1e-20 71.2 0.0 1.9e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02506.1 - 9.7e-15 54.7 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY02506.1 - 6.6e-12 46.0 0.0 1.1e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY02506.1 - 3.2e-11 43.0 0.0 5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY02506.1 - 6.8e-08 32.5 0.0 7.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORY02506.1 - 0.00016 20.9 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_15 PF09445.10 ORY02506.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 ORY02506.1 - 0.0032 16.8 0.0 0.0075 15.6 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 ORY02506.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 ORY02506.1 - 0.017 14.6 0.0 0.074 12.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 ORY02506.1 - 0.058 11.9 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 ORY02506.1 - 0.062 12.9 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF669 PF05037.13 ORY02506.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Methyltransf_11 PF08241.12 ORY02507.1 - 2.6e-22 79.2 0.0 4.8e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02507.1 - 9.9e-20 71.1 0.0 2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02507.1 - 1.1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY02507.1 - 7e-12 46.0 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY02507.1 - 1.5e-11 44.1 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY02507.1 - 9.7e-08 32.0 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORY02507.1 - 0.00015 20.9 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_15 PF09445.10 ORY02507.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 ORY02507.1 - 0.0031 16.8 0.1 0.0073 15.6 0.1 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 ORY02507.1 - 0.0064 16.4 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 ORY02507.1 - 0.026 14.1 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 ORY02507.1 - 0.068 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.11 ORY02507.1 - 0.12 12.1 0.0 0.53 9.9 0.0 1.9 1 1 1 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DUF669 PF05037.13 ORY02507.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Methyltransf_29 PF03141.16 ORY02507.1 - 0.15 10.5 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 ORY02508.1 - 1.8e-21 76.6 0.0 2.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02508.1 - 2.7e-19 69.7 0.0 4.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02508.1 - 9.8e-15 54.7 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY02508.1 - 2.3e-14 53.3 0.0 3.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ORY02508.1 - 3.2e-10 40.6 0.0 6.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY02508.1 - 5.8e-07 29.5 0.0 1.4e-06 28.2 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain DREV PF05219.12 ORY02508.1 - 1.3e-06 27.7 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 ORY02508.1 - 7.7e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 ORY02508.1 - 0.028 14.0 0.0 0.26 10.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 ORY02508.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HSP70 PF00012.20 ORY02509.1 - 2.4e-267 888.0 15.2 2.8e-267 887.8 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY02509.1 - 6e-15 54.9 4.5 7.2e-13 48.0 2.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORY02509.1 - 0.016 15.6 6.3 1.1 9.7 0.2 3.7 3 2 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 ORY02509.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DMRL_synthase PF00885.19 ORY02509.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Spc7 PF08317.11 ORY02509.1 - 0.26 10.1 7.6 0.52 9.2 7.6 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Rad21_Rec8_N PF04825.13 ORY02510.1 - 2.2e-38 130.8 0.0 4e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORY02510.1 - 3.4e-15 55.1 0.0 1e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 ORY02510.1 - 0.02 14.8 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 Segregation and condensation protein ScpA NAC PF01849.18 ORY02511.1 - 1.1e-22 79.7 0.4 2e-22 78.9 0.4 1.4 1 0 0 1 1 1 1 NAC domain Peptidase_C39 PF03412.15 ORY02511.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family Cmc1 PF08583.10 ORY02512.1 - 5.8e-16 58.3 0.9 6.7e-16 58.1 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Atg31 PF09795.9 ORY02513.1 - 0.0043 17.1 0.9 0.0084 16.1 0.9 1.5 1 1 0 1 1 1 1 Autophagy-related protein 31 FAS_meander PF17951.1 ORY02513.1 - 0.036 13.9 0.2 0.048 13.5 0.2 1.1 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Mo25 PF08569.11 ORY02514.1 - 3.8e-109 365.0 3.3 4.3e-109 364.8 3.3 1.0 1 0 0 1 1 1 1 Mo25-like DUF2267 PF10025.9 ORY02514.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Ribosomal_L24e PF01246.20 ORY02515.1 - 4.2e-33 113.4 0.3 4.2e-33 113.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CDPS PF16715.5 ORY02515.1 - 0.43 10.2 5.7 0.62 9.7 5.7 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase DDHD PF02862.17 ORY02515.1 - 1.5 9.0 5.0 1.8 8.6 5.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF4396 PF14342.6 ORY02516.1 - 2.3e-34 118.8 1.7 3.5e-34 118.2 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) SprT-like PF10263.9 ORY02517.1 - 3.8e-27 94.4 1.2 6.9e-27 93.5 1.2 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.19 ORY02517.1 - 0.00015 22.1 1.0 0.00034 21.0 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 ORY02517.1 - 0.0053 17.4 1.0 0.009 16.6 0.1 1.9 2 0 0 2 2 2 1 YABBY protein Zn_ribbon_SprT PF17283.2 ORY02517.1 - 0.02 14.8 2.6 0.046 13.6 2.6 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Tox-MPTase2 PF15638.6 ORY02517.1 - 0.18 11.6 0.4 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Metallopeptidase toxin 2 DUF441 PF04284.13 ORY02518.1 - 0.058 13.4 0.2 0.088 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF441) Cation_efflux PF01545.21 ORY02519.1 - 5.4e-49 166.6 16.8 6.5e-49 166.4 16.8 1.1 1 0 0 1 1 1 1 Cation efflux family Pkinase PF00069.25 ORY02520.1 - 5e-73 245.7 0.0 6.4e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02520.1 - 2.5e-38 131.8 0.0 3.4e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORY02520.1 - 1.9e-15 57.0 1.9 2.5e-15 56.6 0.1 2.1 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 ORY02520.1 - 1.5e-06 27.8 0.0 0.00029 20.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 ORY02520.1 - 3.7e-06 26.4 0.1 5.7e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY02520.1 - 1e-05 24.5 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 ORY02520.1 - 0.00013 22.2 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 ORY02520.1 - 0.0018 17.3 0.2 0.0044 16.0 0.3 1.7 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 ORY02520.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY02520.1 - 0.092 12.7 0.0 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PMI_typeI PF01238.21 ORY02521.1 - 1.7e-124 415.9 0.0 1.9e-124 415.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 ORY02521.1 - 1.5e-07 31.3 0.1 0.0003 20.7 0.0 2.9 3 1 0 3 3 3 2 AraC-like ligand binding domain Cupin_2 PF07883.11 ORY02521.1 - 0.00016 21.3 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain DUF2322 PF10084.9 ORY02521.1 - 0.0037 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2322) AraC_N PF06719.13 ORY02521.1 - 0.094 12.4 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Cupin_6 PF12852.7 ORY02521.1 - 0.16 11.6 0.0 2.6 7.7 0.0 2.8 4 0 0 4 4 4 0 Cupin EF-hand_1 PF00036.32 ORY02522.1 - 6.7e-40 131.7 14.5 6.4e-10 37.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY02522.1 - 2.9e-35 120.5 2.7 5.2e-18 65.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY02522.1 - 1.5e-31 105.6 10.1 2.9e-09 36.1 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORY02522.1 - 2.1e-29 101.1 11.2 3.6e-14 52.3 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORY02522.1 - 9.1e-26 88.2 11.1 2.4e-06 26.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY02522.1 - 2.3e-16 59.8 0.1 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY02522.1 - 3e-10 40.0 2.2 1.2e-05 25.2 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY02522.1 - 4.7e-10 39.8 0.4 0.00012 22.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ORY02522.1 - 1.5e-06 28.3 2.8 0.0006 19.9 0.1 2.9 1 1 3 4 4 4 3 Dockerin type I domain UPF0154 PF03672.13 ORY02522.1 - 3.9e-05 23.6 1.6 0.37 10.9 0.0 3.2 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 ORY02522.1 - 0.00048 20.1 0.8 1.4 8.8 0.0 3.4 1 1 3 4 4 4 2 Caleosin related protein EFhand_Ca_insen PF08726.10 ORY02522.1 - 0.0054 16.8 0.4 0.05 13.7 0.1 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.16 ORY02522.1 - 0.01 16.1 1.1 1.9 8.8 0.6 2.8 1 1 1 2 2 2 0 RNA polymerase Rpb4 GPHH PF16905.5 ORY02522.1 - 0.016 14.9 0.0 12 5.7 0.0 3.3 3 1 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_11 PF08976.11 ORY02522.1 - 0.019 15.8 0.1 2.9 8.8 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain MecA_N PF05223.11 ORY02522.1 - 0.028 14.7 0.3 0.12 12.6 0.1 1.9 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Fe_hyd_lg_C PF02906.14 ORY02522.1 - 0.029 14.1 0.7 0.073 12.7 0.7 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF4497 PF14924.6 ORY02522.1 - 0.04 14.4 0.0 10 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) SurA_N_2 PF13623.6 ORY02522.1 - 0.085 12.7 1.3 1.6 8.6 0.4 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 ORY02522.1 - 0.13 12.5 0.1 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain PMBR PF09373.10 ORY02522.1 - 0.16 12.2 0.0 69 3.9 0.0 3.5 3 0 0 3 3 3 0 Pseudomurein-binding repeat tRNA-synt_1b PF00579.25 ORY02523.1 - 1.4e-71 241.3 0.0 1.7e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HD PF01966.22 ORY02524.1 - 0.0002 21.5 1.5 0.0006 20.0 1.5 1.8 1 1 0 1 1 1 1 HD domain Ribosomal_L7Ae PF01248.26 ORY02525.1 - 3.3e-23 81.2 0.7 3.3e-23 81.2 0.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GalP_UDP_tr_C PF02744.17 ORY02525.1 - 0.038 13.7 0.2 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain ATPase_2 PF01637.18 ORY02525.1 - 0.061 13.2 1.3 0.072 13.0 0.4 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_S15 PF00312.22 ORY02526.1 - 6.6e-29 100.0 0.3 1.3e-28 99.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 Aim21 PF11489.8 ORY02526.1 - 0.018 14.0 1.8 0.024 13.6 1.8 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 CAP PF00188.26 ORY02529.1 - 4.7e-18 66.2 0.1 6.1e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3674 PF12426.8 ORY02534.1 - 0.044 13.8 0.6 5.8 7.0 0.3 2.5 2 0 0 2 2 2 0 RNA dependent RNA polymerase DUF1328 PF07043.13 ORY02534.1 - 0.17 12.1 2.0 9.4 6.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) Pyr_redox_2 PF07992.14 ORY02540.1 - 1.7e-59 201.4 0.1 2.8e-59 200.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TusA PF01206.17 ORY02540.1 - 4.3e-16 58.5 0.0 8.3e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA Pyr_redox PF00070.27 ORY02540.1 - 1.3e-14 54.5 2.9 1.9e-14 54.0 0.1 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY02540.1 - 1.1e-13 51.4 3.9 1.6e-12 47.7 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 ORY02540.1 - 3.1e-13 50.2 0.0 9.3e-13 48.6 0.0 1.8 2 0 0 2 2 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 ORY02540.1 - 1.4e-10 40.9 1.3 1.6e-09 37.5 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY02540.1 - 7.6e-07 29.3 2.7 0.038 14.2 0.2 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY02540.1 - 0.00072 19.6 2.3 1.2 9.1 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY02540.1 - 0.0012 18.0 3.0 0.087 11.9 0.4 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 ORY02540.1 - 0.0052 16.1 0.0 0.12 11.7 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 ORY02540.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 ORY02540.1 - 0.027 14.0 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_binding_2 PF00890.24 ORY02540.1 - 0.029 13.4 5.7 1.2 8.2 0.3 3.2 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 ORY02540.1 - 0.039 13.8 0.9 0.07 13.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RELT PF12606.8 ORY02540.1 - 0.044 12.8 0.1 0.077 12.0 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 HI0933_like PF03486.14 ORY02540.1 - 0.06 12.0 6.1 1.8 7.2 1.0 3.1 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 ORY02540.1 - 0.097 11.9 0.8 0.25 10.5 0.6 1.7 1 1 0 1 1 1 0 FAD binding domain DAO PF01266.24 ORY02540.1 - 0.12 11.9 6.6 0.81 9.2 0.2 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Protoglobin PF11563.8 ORY02541.1 - 7.7e-11 42.1 0.0 9.8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protoglobin AZUL PF16558.5 ORY02584.1 - 9.5e-16 57.8 5.5 2.3e-15 56.5 5.5 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A MA3 PF02847.17 ORY02585.1 - 1.6e-28 98.9 1.1 4e-28 97.7 1.1 1.7 1 0 0 1 1 1 1 MA3 domain Thr_synth_N PF14821.6 ORY02585.1 - 0.12 12.6 0.0 4.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus Myb_Cef PF11831.8 ORY02586.1 - 5.9e-48 163.5 1.4 5.9e-48 163.5 1.4 3.9 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 ORY02586.1 - 4.5e-21 74.8 11.7 1.9e-11 43.9 1.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY02586.1 - 2e-20 72.8 7.4 9.5e-14 51.4 3.2 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain ATP_bind_1 PF03029.17 ORY02587.1 - 5.8e-84 281.7 0.1 6.8e-84 281.4 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORY02587.1 - 0.00013 21.0 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 ORY02587.1 - 0.00078 19.4 0.0 0.0076 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY02587.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORY02587.1 - 0.0045 17.0 0.0 0.005 16.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY02587.1 - 0.0078 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 ORY02587.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 ORY02587.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 ORY02587.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY02587.1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY02587.1 - 0.039 14.1 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORY02587.1 - 0.042 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 ORY02587.1 - 0.054 12.9 0.0 0.85 9.0 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family cobW PF02492.19 ORY02587.1 - 0.078 12.6 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORY02587.1 - 0.081 13.5 0.3 0.22 12.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ORY02587.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORY02587.1 - 0.12 12.8 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY02587.1 - 0.16 12.3 0.1 0.45 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORY02587.1 - 0.17 11.8 0.1 0.49 10.3 0.1 1.7 2 0 0 2 2 2 0 NTPase Got1 PF04178.12 ORY02588.1 - 4.5e-35 120.5 14.5 6.7e-35 119.9 14.5 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 ORY02588.1 - 5.1 5.3 11.0 6.2 5.0 11.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ras PF00071.22 ORY02589.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Ras family Bacillus_HBL PF05791.11 ORY02589.1 - 0.036 13.9 0.7 0.075 12.9 0.7 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4482 PF14818.6 ORY02589.1 - 9.2 7.1 9.1 16 6.4 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Mito_carr PF00153.27 ORY02590.1 - 3e-65 216.2 2.7 1.3e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1295 PF06966.12 ORY02592.1 - 2e-38 132.3 6.5 3.4e-38 131.5 6.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ORY02592.1 - 0.00019 21.5 1.6 0.00019 21.5 1.6 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORY02592.1 - 0.0004 20.7 0.4 0.0004 20.7 0.4 2.9 3 1 1 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 ORY02592.1 - 0.012 16.0 0.1 0.012 16.0 0.1 2.7 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MBOAT PF03062.19 ORY02593.1 - 3.5e-52 177.9 23.9 3.5e-52 177.9 23.9 2.2 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PHO4 PF01384.20 ORY02593.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 1 0 1 1 1 0 Phosphate transporter family Glycos_transf_1 PF00534.20 ORY02594.1 - 7e-34 116.8 0.0 4.4e-33 114.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY02594.1 - 1.5e-15 57.6 0.0 2.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ORY02594.1 - 3.8e-15 56.5 0.0 6.7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY02594.1 - 2e-07 31.6 0.0 3.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ORY02594.1 - 0.00048 20.5 0.0 0.00097 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_L39 PF00832.20 ORY02595.1 - 5.1e-23 80.4 10.8 5.8e-23 80.3 10.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein NPL PF17800.1 ORY02596.1 - 4.1e-24 85.1 0.6 7.1e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 ORY02596.1 - 5.6e-22 77.9 0.0 1.7e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NAP PF00956.18 ORY02597.1 - 7.8e-92 307.3 13.7 7.8e-92 307.3 13.7 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 ORY02597.1 - 0.0041 16.9 9.1 0.0041 16.9 9.1 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Dynamin_M PF01031.20 ORY02597.1 - 0.013 14.8 0.7 0.021 14.1 0.7 1.3 1 0 0 1 1 1 0 Dynamin central region BUD22 PF09073.10 ORY02597.1 - 1.8 7.8 23.0 1.3e+02 1.7 23.0 2.0 1 1 0 1 1 1 0 BUD22 RabGAP-TBC PF00566.18 ORY02598.1 - 0.00034 20.3 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sof1 PF04158.14 ORY02599.1 - 1.8e-33 114.7 14.9 3.1e-33 113.9 14.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 ORY02599.1 - 1.9e-29 101.3 4.9 0.00022 21.9 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02599.1 - 1.3e-08 35.0 0.0 0.13 12.6 0.0 4.2 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORY02599.1 - 0.00027 20.9 0.0 2.9 8.0 0.0 4.0 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Ntox21 PF15526.6 ORY02599.1 - 0.12 12.7 1.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Novel toxin 21 DnaJ PF00226.31 ORY02600.1 - 5.5e-23 80.9 2.3 5.5e-23 80.9 2.3 2.4 3 0 0 3 3 2 1 DnaJ domain DUF4523 PF15023.6 ORY02600.1 - 6.6e-09 35.8 1.9 1.1e-08 35.0 1.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_1 PF00076.22 ORY02600.1 - 0.00016 21.4 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apo-CIII PF05778.12 ORY02600.1 - 0.006 16.2 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 Apolipoprotein CIII (Apo-CIII) TM1506 PF08973.10 ORY02600.1 - 0.016 14.8 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) Salp15 PF12115.8 ORY02600.1 - 2.7 8.5 9.2 1.1 9.7 5.4 2.0 1 1 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation FapA PF03961.13 ORY02600.1 - 3.1 6.3 14.1 4.6 5.7 14.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2235 PF09994.9 ORY02600.1 - 3.4 6.9 7.0 1.7 8.0 4.8 1.5 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Prominin PF05478.11 ORY02600.1 - 4.6 5.1 9.1 5.9 4.7 9.1 1.1 1 0 0 1 1 1 0 Prominin Presenilin PF01080.17 ORY02600.1 - 5.9 5.5 8.7 7.6 5.2 8.7 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 ORY02600.1 - 7.5 5.3 14.2 11 4.7 14.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 ORY02600.1 - 8 5.2 11.5 11 4.7 11.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_S17e PF00833.18 ORY02601.1 - 1.4e-64 215.5 0.2 1.6e-64 215.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Pkinase PF00069.25 ORY02602.1 - 1.4e-65 221.3 0.0 2.1e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02602.1 - 1.3e-38 132.8 0.0 2.1e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3552 PF12072.8 ORY02602.1 - 2.2e-05 23.9 9.2 3.9e-05 23.2 9.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Haspin_kinase PF12330.8 ORY02602.1 - 0.00074 18.6 0.2 0.00074 18.6 0.2 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 ORY02602.1 - 0.00078 18.8 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like ATG16 PF08614.11 ORY02602.1 - 0.00086 19.6 8.8 0.0015 18.8 8.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Pkinase_fungal PF17667.1 ORY02602.1 - 0.018 13.8 0.3 0.035 12.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 ORY02602.1 - 0.026 14.4 0.3 0.026 14.4 0.3 2.6 2 2 1 3 3 3 0 Phosphotransferase enzyme family Folliculin_C PF16692.5 ORY02602.1 - 0.092 12.5 1.4 0.16 11.7 1.4 1.3 1 0 0 1 1 1 0 Folliculin C-terminal domain Exonuc_VII_L PF02601.15 ORY02602.1 - 0.55 9.8 5.2 0.84 9.1 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit P66_CC PF16563.5 ORY02602.1 - 1.3 8.7 12.1 0.097 12.3 4.4 2.9 1 1 2 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 BLOC1_2 PF10046.9 ORY02602.1 - 1.3 9.4 11.3 0.11 12.8 4.9 2.3 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 ORY02602.1 - 1.6 9.4 6.2 20 5.9 1.3 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF16 PF01519.16 ORY02602.1 - 9.2 6.8 10.0 1.2 9.7 5.8 1.8 2 1 0 2 2 1 0 Protein of unknown function DUF16 Iso_dh PF00180.20 ORY02604.1 - 6.4e-80 268.9 0.0 7.7e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-UBP PF02148.19 ORY02605.1 - 0.00025 21.3 9.0 0.00033 20.9 9.0 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 ORY02605.1 - 0.075 12.8 2.9 0.096 12.5 2.9 1.2 1 0 0 1 1 1 0 Variant UBP zinc finger TauD PF02668.16 ORY02606.1 - 8.6e-55 186.4 0.0 1.1e-54 186.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MBOAT PF03062.19 ORY02607.1 - 1.7e-20 73.7 21.6 2.9e-20 72.9 21.6 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family GATA PF00320.27 ORY02607.1 - 6.2e-06 25.7 0.7 1.4e-05 24.6 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger MBOAT_2 PF13813.6 ORY02607.1 - 0.00028 21.1 2.9 0.00028 21.1 2.9 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Pex14_N PF04695.13 ORY02607.1 - 0.027 15.1 2.4 0.23 12.1 0.1 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_16 PF00722.21 ORY02608.1 - 8.4e-36 123.1 5.4 1.2e-35 122.6 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ORY02608.1 - 0.56 10.7 9.0 1.3 9.6 9.0 1.6 1 0 0 1 1 1 0 Chitin recognition protein WSD PF15613.6 ORY02609.1 - 7.9e-13 48.7 0.1 7.9e-13 48.7 0.1 2.9 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MC1 PF05854.11 ORY02609.1 - 4.3 7.7 8.6 1 9.7 1.7 2.4 2 0 0 2 2 2 0 Non-histone chromosomal protein MC1 zf-C2H2 PF00096.26 ORY02610.1 - 1.4e-12 47.3 10.4 1.2e-06 28.6 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY02610.1 - 1e-10 41.5 16.2 3.3e-07 30.4 2.9 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY02610.1 - 1.9e-05 25.1 10.3 0.0047 17.7 0.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY02610.1 - 0.024 14.9 6.0 0.054 13.8 1.0 2.9 1 1 2 3 3 3 0 C2H2-type zinc ribbon Ogr_Delta PF04606.12 ORY02610.1 - 0.033 14.2 3.9 0.059 13.4 2.0 2.3 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF1590 PF07629.11 ORY02610.1 - 0.035 13.9 0.4 0.22 11.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1590) Zn-C2H2_12 PF18112.1 ORY02610.1 - 0.04 14.4 1.5 1.2 9.7 0.8 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 ORY02610.1 - 0.12 12.1 0.6 0.21 11.3 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4461 PF14688.6 ORY02611.1 - 0.0088 15.9 0.5 0.013 15.3 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) CENP-F_leu_zip PF10473.9 ORY02611.1 - 0.022 14.8 3.1 0.03 14.3 3.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 ORY02611.1 - 0.023 15.0 2.6 0.19 12.1 1.2 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 ORY02611.1 - 0.026 14.4 0.3 0.036 13.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 ORY02611.1 - 0.038 14.2 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 ORY02611.1 - 0.066 13.3 1.4 0.18 11.9 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3053 PF11254.8 ORY02611.1 - 0.099 12.2 0.4 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Prefoldin_2 PF01920.20 ORY02611.1 - 0.15 12.0 3.0 0.86 9.6 0.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit Phage_HK97_TLTM PF06120.11 ORY02611.1 - 0.21 10.7 4.6 0.95 8.6 4.6 1.8 1 1 0 1 1 1 0 Tail length tape measure protein FlaC_arch PF05377.11 ORY02611.1 - 0.26 11.7 1.3 2.2 8.7 0.4 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 ORY02611.1 - 1.4 9.2 4.7 17 5.7 0.4 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II PCI PF01399.27 ORY02612.1 - 2e-12 47.5 0.7 6.1e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 ORY02612.1 - 7.3e-07 28.7 2.1 2.1e-06 27.2 2.1 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix CEP209_CC5 PF16574.5 ORY02612.1 - 0.09 12.9 0.3 0.62 10.2 0.1 2.4 2 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 FA_hydroxylase PF04116.13 ORY02613.1 - 5.2e-25 88.3 19.8 5.2e-25 88.3 19.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SE PF08491.10 ORY02614.1 - 2e-103 345.2 0.0 2.7e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ORY02614.1 - 1.2e-12 47.8 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY02614.1 - 7.5e-08 32.3 0.0 7.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY02614.1 - 6.1e-06 25.6 0.1 0.0069 15.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 ORY02614.1 - 6.8e-06 25.4 0.1 2.7e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORY02614.1 - 1.7e-05 25.0 0.0 4.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ORY02614.1 - 0.00036 20.5 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORY02614.1 - 0.0044 16.1 0.0 3.3 6.7 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY02614.1 - 0.0061 15.5 0.3 3.8 6.3 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.17 ORY02614.1 - 0.018 14.3 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 ORY02614.1 - 0.02 14.3 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY02614.1 - 0.033 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY02614.1 - 0.037 14.6 0.2 0.19 12.3 0.0 2.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY02614.1 - 0.038 12.7 0.2 0.076 11.7 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 ORY02614.1 - 0.04 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ORY02614.1 - 0.045 14.0 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 ORY02614.1 - 0.083 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ORY02614.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ORY02614.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SWIB PF02201.18 ORY02615.1 - 3.1e-22 78.3 0.1 6.9e-22 77.1 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain fn3 PF00041.21 ORY02615.1 - 0.01 16.2 0.0 0.54 10.6 0.0 2.6 2 1 1 3 3 3 0 Fibronectin type III domain Acyl-CoA_dh_1 PF00441.24 ORY02616.1 - 7.5e-42 143.1 0.0 1.4e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY02616.1 - 3.6e-40 137.1 0.0 6.8e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY02616.1 - 1e-26 92.9 0.0 1.9e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY02616.1 - 6.5e-13 49.1 0.0 1.5e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain FA_hydroxylase PF04116.13 ORY02617.1 - 3.3e-25 89.0 20.8 3.3e-25 89.0 20.8 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-FCS PF06467.14 ORY02617.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Synaptobrevin PF00957.21 ORY02618.1 - 0.04 13.7 0.2 0.087 12.6 0.2 1.6 1 1 0 1 1 1 0 Synaptobrevin LRR_6 PF13516.6 ORY02619.1 - 8.1e-10 38.0 24.0 0.31 11.2 0.1 9.3 11 0 0 11 11 11 5 Leucine Rich repeat UBA PF00627.31 ORY02619.1 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain LRR_4 PF12799.7 ORY02619.1 - 0.0021 18.4 17.6 0.11 13.0 0.0 6.1 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY02619.1 - 0.071 13.7 10.7 49 5.0 0.2 7.2 7 1 0 7 7 7 0 Leucine Rich Repeat DUF4055 PF13264.6 ORY02619.1 - 0.17 12.1 0.7 0.35 11.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) OCC1 PF15506.6 ORY02619.1 - 0.19 11.9 0.7 0.61 10.2 0.7 1.9 1 0 0 1 1 1 0 OCC1 family AA_kinase PF00696.28 ORY02620.1 - 9.4e-39 133.4 1.9 9.6e-39 133.4 1.1 1.4 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 ORY02620.1 - 3.9e-07 29.9 0.1 1.3e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 PUA domain Nucleotid_trans PF03407.16 ORY02620.1 - 0.19 11.7 0.0 0.42 10.5 0.0 1.5 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase GDP_Man_Dehyd PF16363.5 ORY02621.1 - 3.6e-72 243.6 0.0 4.6e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY02621.1 - 6.7e-58 196.0 0.1 8.3e-58 195.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY02621.1 - 1.6e-25 89.7 0.1 2e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY02621.1 - 7.9e-19 67.8 1.0 3.3e-17 62.5 0.6 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY02621.1 - 2.9e-17 62.8 0.0 2.9e-16 59.4 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY02621.1 - 3.9e-16 59.0 0.0 5.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY02621.1 - 8.9e-06 25.7 0.0 2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GATA PF00320.27 ORY02622.1 - 9.7e-16 57.1 2.4 1.7e-15 56.3 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY02622.1 - 0.0069 15.9 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY02622.1 - 0.081 13.1 0.3 0.25 11.5 0.3 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Ribosomal_L37e PF01907.19 ORY02623.1 - 1.1e-27 95.9 13.0 1.8e-27 95.2 13.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORY02623.1 - 0.0061 16.6 1.6 0.0097 15.9 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORY02623.1 - 0.035 14.1 0.9 0.049 13.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 ORY02623.1 - 0.21 11.1 3.5 2.2 7.8 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 ORY02623.1 - 0.7 9.8 5.4 1.1 9.1 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 ORY02623.1 - 2.2 7.7 5.2 1.2 8.6 3.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) WD40 PF00400.32 ORY02624.1 - 1.8e-21 76.0 14.8 1.4e-06 28.9 0.4 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02624.1 - 4.8e-05 23.6 0.0 3.1 8.2 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3222 PF11519.8 ORY02624.1 - 0.079 13.2 0.2 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DnaJ PF00226.31 ORY02625.1 - 5.8e-25 87.2 0.2 1.8e-24 85.7 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 ORY02625.1 - 1.4e-24 86.4 4.4 3.1e-24 85.3 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Methyltransf_32 PF13679.6 ORY02626.1 - 1e-25 90.5 2.7 1.4e-25 90.2 2.7 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02626.1 - 3.7e-06 27.5 0.4 8.9e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY02626.1 - 0.00033 20.2 0.3 0.00062 19.4 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORY02626.1 - 0.0018 18.9 0.0 0.0065 17.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY02626.1 - 0.0063 16.5 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY02626.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02626.1 - 0.0093 15.8 1.2 0.013 15.3 1.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0146 PF03686.13 ORY02626.1 - 0.01 15.7 0.3 0.036 13.9 0.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0146) PrmA PF06325.13 ORY02626.1 - 0.03 13.7 0.2 0.045 13.1 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 ORY02626.1 - 0.05 13.0 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 ORY02626.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SH3_9 PF14604.6 ORY02627.1 - 4.5e-09 36.0 0.1 6.5e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY02627.1 - 8.2e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY02627.1 - 0.012 15.3 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Variant SH3 domain DUF1647 PF07801.11 ORY02628.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Anemone_cytotox PF06369.12 ORY02628.1 - 0.18 11.4 0.6 0.31 10.7 0.6 1.3 1 0 0 1 1 1 0 Sea anemone cytotoxic protein TLD PF07534.16 ORY02629.1 - 1.2e-26 93.5 0.2 2e-26 92.9 0.2 1.3 1 0 0 1 1 1 1 TLD GATA PF00320.27 ORY02630.1 - 6e-18 64.2 3.2 7.7e-18 63.8 3.2 1.2 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY02630.1 - 0.011 15.2 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 ORY02630.1 - 0.027 13.9 2.6 0.98 8.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 ORY02630.1 - 0.1 12.8 1.5 0.14 12.3 1.5 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SET PF00856.28 ORY02632.1 - 2e-10 41.3 0.2 1.4e-08 35.3 0.0 2.1 1 1 1 2 2 2 2 SET domain EamA PF00892.20 ORY02633.1 - 1.5e-14 54.4 25.4 2.5e-08 34.2 3.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORY02633.1 - 5e-11 42.3 1.9 6.3e-11 42.0 1.9 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 ORY02633.1 - 1.3e-08 34.5 11.6 4.1e-08 32.9 11.6 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 ORY02633.1 - 3.8e-06 26.3 1.2 7.8e-06 25.3 1.2 1.6 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 ORY02633.1 - 2.6e-05 23.6 11.8 5.9e-05 22.4 11.8 1.5 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 ORY02633.1 - 0.00012 21.1 6.1 0.00012 21.1 6.1 2.4 2 1 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like Bax1-I PF01027.20 ORY02633.1 - 0.0013 18.7 7.9 0.0013 18.7 7.9 3.0 2 1 1 3 3 3 1 Inhibitor of apoptosis-promoting Bax1 DMT_6 PF04342.12 ORY02633.1 - 3.2 8.0 10.0 11 6.2 2.2 2.9 2 1 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Acetyltransf_1 PF00583.25 ORY02634.1 - 3.4e-15 56.3 0.0 4.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY02634.1 - 3.2e-10 40.3 0.1 4.7e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY02634.1 - 7.4e-10 38.9 0.2 9.6e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY02634.1 - 5.6e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ORY02634.1 - 0.00028 21.1 0.2 0.00047 20.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY02634.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 ORY02634.1 - 0.037 14.3 0.1 0.11 12.7 0.0 1.8 2 1 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_8 PF13523.6 ORY02634.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ORY02634.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY02634.1 - 0.089 13.5 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BCL9 PF11502.8 ORY02634.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein PALP PF00291.25 ORY02635.1 - 1.5e-56 192.0 0.1 2.9e-56 191.0 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORY02635.1 - 3.4e-13 49.8 0.3 2.1e-09 37.7 0.0 3.2 2 1 0 2 2 2 2 CBS domain ArsA_HSP20 PF17886.1 ORY02635.1 - 0.15 11.6 0.0 34 4.1 0.0 3.2 3 0 0 3 3 3 0 HSP20-like domain found in ArsA Ion_trans PF00520.31 ORY02636.1 - 9.5e-09 34.8 8.1 1.2e-08 34.5 8.1 1.1 1 0 0 1 1 1 1 Ion transport protein FadA PF09403.10 ORY02636.1 - 0.048 14.1 0.7 0.067 13.7 0.7 1.2 1 0 0 1 1 1 0 Adhesion protein FadA DUF3742 PF12553.8 ORY02636.1 - 0.09 12.9 4.6 0.13 12.4 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) PfkB PF00294.24 ORY02637.1 - 4.2e-71 239.7 0.0 4.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Mito_carr PF00153.27 ORY02638.1 - 8.7e-61 201.9 2.0 1.6e-19 69.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C14 PF00656.22 ORY02639.1 - 6.9e-55 186.7 0.1 1.1e-54 186.0 0.1 1.3 1 0 0 1 1 1 1 Caspase domain RabGAP-TBC PF00566.18 ORY02640.1 - 1.5e-57 194.7 0.1 1.9e-57 194.4 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sel1 PF08238.12 ORY02641.1 - 2e-19 69.6 8.0 8.9e-07 29.4 0.0 4.5 4 1 0 4 4 4 4 Sel1 repeat TPR_2 PF07719.17 ORY02641.1 - 0.035 14.2 0.1 0.035 14.2 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MINDY_DUB PF04424.13 ORY02641.1 - 0.1 12.6 0.1 3.7 7.6 0.0 2.7 2 1 1 3 3 3 0 MINDY deubiquitinase TPR_1 PF00515.28 ORY02641.1 - 0.25 11.2 0.1 0.25 11.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UPRTase PF14681.6 ORY02642.1 - 3.9e-67 225.7 0.0 4.5e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY02642.1 - 2e-05 24.1 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MukF_C PF17193.4 ORY02642.1 - 0.12 12.6 0.1 0.47 10.6 0.1 1.7 1 1 0 2 2 2 0 MukF C-terminal domain GTP_CH_N PF12471.8 ORY02643.1 - 3e-88 294.6 0.0 4.3e-88 294.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ORY02643.1 - 3.5e-17 62.5 0.0 5.2e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Mito_carr PF00153.27 ORY02644.1 - 9.4e-63 208.2 1.4 9.4e-25 86.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Put_Phosphatase PF06888.12 ORY02645.1 - 2.8e-47 161.1 0.8 5.4e-47 160.2 0.8 1.4 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 ORY02645.1 - 0.00033 21.0 0.2 0.53 10.5 0.0 2.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY02645.1 - 0.00091 19.3 0.4 0.023 14.8 0.2 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY02645.1 - 0.047 14.1 0.0 0.66 10.4 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hormone_recep PF00104.30 ORY02645.1 - 0.24 11.0 2.2 0.21 11.1 0.7 1.8 2 1 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor A_deaminase PF00962.22 ORY02646.1 - 3.2e-125 417.8 0.1 5.3e-125 417.1 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase PRCH PF03967.13 ORY02647.1 - 0.97 9.7 3.9 1.6 9.0 3.9 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF1688 PF07958.11 ORY02648.1 - 3.1e-177 589.5 0.0 3.5e-177 589.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 ORY02648.1 - 0.016 14.8 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family YccF PF03733.13 ORY02649.1 - 8.4e-24 84.0 14.9 7.5e-18 65.0 8.7 2.0 2 0 0 2 2 2 2 Inner membrane component domain RGS PF00615.19 ORY02650.1 - 1.6e-09 38.1 0.4 2.8e-09 37.3 0.4 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ribonuc_L-PSP PF01042.21 ORY02651.1 - 1.8e-21 76.4 0.0 2.2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_M24 PF00557.24 ORY02651.1 - 0.049 13.3 0.0 0.88 9.2 0.0 2.0 1 1 1 2 2 2 0 Metallopeptidase family M24 PorA PF11271.8 ORY02651.1 - 0.061 12.6 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Porin PorA M16C_assoc PF08367.11 ORY02652.1 - 8.8e-79 264.2 0.1 1.4e-78 263.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 ORY02652.1 - 2.3e-30 105.9 0.1 5e-21 75.5 0.1 3.1 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY02652.1 - 4.5e-09 36.5 0.1 2.2e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Pantoate_ligase PF02569.15 ORY02652.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Phage_int_SAM_1 PF02899.17 ORY02652.1 - 0.17 12.2 0.3 0.88 9.9 0.1 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain TPR_1 PF00515.28 ORY02695.1 - 3.8e-07 29.7 0.0 6.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02695.1 - 1.2e-06 28.3 0.8 3.8e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02695.1 - 1.8e-06 27.6 0.0 3.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02695.1 - 2.8e-05 24.6 0.4 5.2e-05 23.7 0.2 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY02695.1 - 0.00067 19.3 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.6 ORY02695.1 - 0.0022 18.1 0.1 0.0029 17.7 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.8 ORY02695.1 - 0.0072 15.3 1.3 0.0081 15.1 1.3 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 BTAD PF03704.17 ORY02695.1 - 0.0097 16.3 0.4 0.012 16.1 0.4 1.1 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 ORY02695.1 - 0.029 14.9 0.1 0.062 13.8 0.1 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY02695.1 - 0.038 14.6 1.3 0.27 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_5 PF01022.20 ORY02695.1 - 0.052 13.4 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TPR_16 PF13432.6 ORY02695.1 - 0.053 14.2 0.2 0.081 13.6 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02695.1 - 0.078 13.3 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Velvet PF11754.8 ORY02696.1 - 1.4e-35 123.5 0.1 1.5e-35 123.4 0.1 1.0 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORY02697.1 - 4e-38 131.8 0.1 4.6e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Velvet factor Redoxin PF08534.10 ORY02698.1 - 8e-25 87.3 0.0 9.2e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY02698.1 - 1e-10 41.6 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hydrolase PF00702.26 ORY02698.1 - 0.21 11.8 0.0 0.25 11.6 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase P5CR_dimer PF14748.6 ORY02699.1 - 9.4e-37 125.4 2.2 9.4e-37 125.4 2.2 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORY02699.1 - 3.4e-13 50.0 0.5 1.3e-12 48.1 0.5 2.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ORY02699.1 - 0.095 12.7 1.3 0.36 10.8 1.3 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus LRR_8 PF13855.6 ORY02700.1 - 5.9e-51 170.1 75.4 7.7e-12 44.8 0.3 9.8 5 2 4 9 9 9 9 Leucine rich repeat PP2C PF00481.21 ORY02700.1 - 2.3e-44 152.0 0.0 3.9e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 ORY02700.1 - 3.7e-38 128.9 90.6 2.3e-05 24.7 4.7 12.1 9 1 1 11 11 11 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ORY02700.1 - 5.8e-27 94.5 0.0 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RA PF00788.23 ORY02700.1 - 1.3e-06 28.9 0.0 1.4e-05 25.6 0.0 2.5 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 ORY02700.1 - 5.8e-05 23.1 13.7 0.011 15.7 0.4 3.7 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 ORY02700.1 - 0.0013 18.9 80.5 3 8.7 1.0 16.7 17 2 0 17 17 17 6 Leucine Rich Repeat LRR_9 PF14580.6 ORY02700.1 - 0.012 15.1 26.4 0.14 11.6 5.6 5.3 2 1 4 6 6 6 0 Leucine-rich repeat RRM_1 PF00076.22 ORY02701.1 - 1.1e-27 95.6 0.3 4.4e-09 36.0 0.1 4.5 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 ORY02701.1 - 9.7e-09 35.3 0.0 0.002 18.0 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 ORY02701.1 - 3.3e-07 30.1 0.0 0.036 13.9 0.0 3.7 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY02701.1 - 0.004 17.2 0.1 13 6.0 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY02701.1 - 0.062 13.3 0.1 26 4.9 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY02701.1 - 0.064 13.3 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif E1-E2_ATPase PF00122.20 ORY02702.1 - 7.8e-27 94.0 0.0 2.2e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY02702.1 - 1.7e-10 41.5 0.2 2.9e-05 24.5 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY02702.1 - 8e-06 25.5 0.0 2.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY02702.1 - 0.0014 18.7 0.0 0.0091 16.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Fasciclin PF02469.22 ORY02703.1 - 2e-50 170.3 1.0 1.4e-28 99.7 0.3 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF4097 PF13349.6 ORY02703.1 - 0.054 12.8 1.0 0.17 11.2 0.2 1.9 2 0 0 2 2 2 0 Putative adhesin TIG PF01833.24 ORY02703.1 - 0.058 13.5 1.1 8.4 6.5 0.2 2.5 2 0 0 2 2 2 0 IPT/TIG domain DUF211 PF02680.14 ORY02703.1 - 0.21 11.8 1.6 6.2 7.1 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Fasciclin PF02469.22 ORY02704.1 - 3.6e-50 169.5 1.0 2e-28 99.1 0.3 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 ORY02704.1 - 0.15 12.3 0.7 7.9 6.7 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 TIG PF01833.24 ORY02704.1 - 0.32 11.1 5.1 12 6.0 2.7 2.5 2 0 0 2 2 2 0 IPT/TIG domain Cyclin PF08613.11 ORY02705.1 - 2.1e-39 135.5 0.2 2.1e-39 135.5 0.2 1.6 2 0 0 2 2 2 1 Cyclin HIF-1 PF11413.8 ORY02706.1 - 9.1 5.8 7.4 6.5 6.2 0.3 2.7 3 0 0 3 3 3 0 Hypoxia-inducible factor-1 Oxidored_FMN PF00724.20 ORY02707.1 - 1.1e-103 347.2 0.0 1.2e-103 347.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyclin PF08613.11 ORY02708.1 - 1.2e-11 45.2 0.3 1.6e-11 44.9 0.3 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY02708.1 - 4.3e-06 26.5 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain 5_nucleotid_C PF02872.18 ORY02709.1 - 4.8e-32 111.3 0.1 1.1e-31 110.2 0.1 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ORY02709.1 - 1.4e-10 42.0 0.8 3.3e-10 40.8 0.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.25 ORY02710.1 - 3e-51 173.6 0.1 4.2e-51 173.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY02710.1 - 9.4e-36 123.5 0.1 1.2e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY02710.1 - 6.4e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY02710.1 - 2.7e-05 24.2 0.0 5.1e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY02710.1 - 6.6e-05 22.5 0.0 9.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY02710.1 - 0.00049 19.6 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 ORY02710.1 - 0.0084 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 ORY02710.1 - 0.019 14.5 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Thioredoxin_3 PF13192.6 ORY02710.1 - 0.047 13.7 0.9 0.11 12.5 0.2 1.9 2 0 0 2 2 2 0 Thioredoxin domain SurE PF01975.17 ORY02710.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Survival protein SurE RmlD_sub_bind PF04321.17 ORY02710.1 - 0.1 11.7 0.1 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain LEM PF03020.15 ORY02710.1 - 0.16 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 LEM domain UPF0449 PF15136.6 ORY02710.1 - 0.55 10.7 2.3 0.38 11.2 0.4 1.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Transp_cyt_pur PF02133.15 ORY02711.1 - 5.5e-112 374.7 36.6 6.3e-112 374.6 36.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3185 PF11381.8 ORY02711.1 - 0.74 9.9 4.9 0.2 11.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) CSTF2_hinge PF14327.6 ORY02712.1 - 1.1e-24 86.6 3.0 1.1e-24 86.6 3.0 2.5 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 ORY02712.1 - 1.6e-23 82.3 0.1 3.6e-23 81.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 ORY02712.1 - 4.3e-11 42.2 14.8 4.3e-11 42.2 14.8 1.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 ORY02712.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif FliG_N PF14842.6 ORY02712.1 - 0.039 14.5 1.1 0.52 10.9 0.4 2.7 2 1 0 2 2 2 0 FliG N-terminal domain UBA_4 PF14555.6 ORY02712.1 - 0.096 12.5 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain FlxA PF14282.6 ORY02712.1 - 0.42 10.6 11.2 0.24 11.4 1.4 2.3 2 0 0 2 2 2 0 FlxA-like protein Mito_carr PF00153.27 ORY02713.1 - 9.5e-30 102.4 1.9 4.9e-12 45.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY02713.1 - 0.0017 17.5 0.3 0.011 15.0 0.0 2.3 3 0 0 3 3 3 1 Gammaproteobacterial serine protease SPX PF03105.19 ORY02714.1 - 4.5e-29 102.6 0.1 1.4e-15 58.1 2.3 3.1 1 1 2 3 3 3 2 SPX domain zf-C3HC4_4 PF15227.6 ORY02714.1 - 1.5e-07 31.4 9.7 4.1e-07 30.0 8.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY02714.1 - 2.8e-07 30.3 7.2 5.4e-07 29.4 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY02714.1 - 3.8e-06 27.1 10.5 3.8e-06 27.1 10.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY02714.1 - 6.4e-06 25.9 9.2 6.4e-06 25.9 9.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY02714.1 - 1.9e-05 24.4 10.2 1.9e-05 24.4 10.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY02714.1 - 4.8e-05 23.3 10.1 0.00011 22.1 10.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY02714.1 - 0.003 17.5 11.9 0.003 17.5 11.9 2.4 2 1 1 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY02714.1 - 0.0031 17.3 10.1 0.015 15.1 10.2 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 CagE_TrbE_VirB PF03135.14 ORY02714.1 - 0.01 15.9 0.7 0.27 11.3 0.3 2.2 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system TerY_C PF15616.6 ORY02714.1 - 0.13 12.3 2.3 0.26 11.4 2.3 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 ORY02714.1 - 0.15 12.2 3.7 0.32 11.2 3.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY02714.1 - 0.56 10.5 9.4 2.1 8.7 9.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zn-ribbon_8 PF09723.10 ORY02714.1 - 0.81 9.9 3.8 4.1 7.6 2.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 ORY02714.1 - 1.3 8.8 9.4 0.11 12.3 3.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Solute_trans_a PF03619.16 ORY02715.1 - 7.1e-92 307.7 24.4 1.1e-91 307.1 24.4 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ctr PF04145.15 ORY02716.1 - 7.9e-23 81.7 13.4 1.9e-15 57.7 6.9 2.0 1 1 1 2 2 2 2 Ctr copper transporter family HemY_N PF07219.13 ORY02716.1 - 2.9 8.1 9.3 1 9.6 0.7 2.1 1 1 1 2 2 2 0 HemY protein N-terminus TPT PF03151.16 ORY02717.1 - 1.1e-63 215.4 27.4 1.2e-63 215.1 27.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY02717.1 - 5.1e-14 52.6 37.9 5.5e-08 33.1 15.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY02717.1 - 4.2e-10 39.3 31.4 5.3e-10 39.0 31.4 1.1 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 ORY02717.1 - 0.013 16.1 2.5 0.013 16.1 2.5 3.2 2 1 1 3 3 3 0 Small Multidrug Resistance protein DUF4536 PF15055.6 ORY02717.1 - 0.086 13.1 0.0 0.086 13.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) DUF2937 PF11157.8 ORY02717.1 - 0.42 10.3 3.0 7.9 6.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) MHYT PF03707.16 ORY02717.1 - 1 9.5 9.4 4.7 7.4 0.0 3.7 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat Cyclin PF08613.11 ORY02718.1 - 1.9e-11 44.6 0.0 2.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY02718.1 - 4.1e-08 33.0 0.0 5.2e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain RhoGAP PF00620.27 ORY02719.1 - 2e-36 125.1 0.0 3.5e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mpv17_PMP22 PF04117.12 ORY02720.1 - 3.2e-24 84.9 0.4 7.9e-24 83.7 0.4 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 ORY02721.1 - 5.3e-22 77.8 0.2 9.4e-22 77.0 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pkinase PF00069.25 ORY02722.1 - 5.3e-53 180.1 0.0 2.4e-52 177.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02722.1 - 3.2e-17 62.7 0.1 1.5e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY02722.1 - 0.054 12.9 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf_CCCH_4 PF18345.1 ORY02723.1 - 5.6e-06 26.2 4.0 1.1e-05 25.3 4.0 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 ORY02723.1 - 7.3e-06 25.7 1.5 1.9e-05 24.4 1.5 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 ORY02723.1 - 0.00094 19.0 1.1 0.0018 18.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY02723.1 - 0.0017 19.0 0.2 0.0035 18.0 0.2 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 ORY02723.1 - 0.2 12.2 1.6 0.38 11.3 1.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger UPF0193 PF05250.11 ORY02723.1 - 0.21 11.4 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) G-alpha PF00503.20 ORY02724.1 - 6.6e-124 413.6 5.9 7.6e-124 413.4 5.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY02724.1 - 1.2e-15 57.4 3.1 3.2e-11 43.0 0.4 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ORY02724.1 - 6.4e-06 25.9 0.4 2.2e-05 24.2 0.2 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORY02724.1 - 0.0021 17.4 6.8 0.0025 17.2 0.4 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 ORY02724.1 - 0.047 13.0 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY02724.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORY02724.1 - 0.064 13.5 0.3 9.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY02724.1 - 0.087 12.9 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DAP3 PF10236.9 ORY02724.1 - 0.12 11.5 0.6 0.21 10.7 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DHHC PF01529.20 ORY02725.1 - 1.2e-38 132.2 12.0 1.2e-38 132.2 12.0 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.25 ORY02725.1 - 0.029 14.9 9.0 0.063 13.8 9.0 1.5 1 0 0 1 1 1 0 Plexin repeat COX14 PF14880.6 ORY02725.1 - 0.17 11.7 0.6 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MFS_1 PF07690.16 ORY02727.1 - 1.3e-19 70.3 26.5 2e-19 69.7 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY02727.1 - 1e-14 54.6 5.9 1e-14 54.6 5.9 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 ORY02727.1 - 0.094 11.7 15.1 0.048 12.7 7.9 3.2 2 2 1 3 3 3 0 PUCC protein CPP1-like PF11833.8 ORY02727.1 - 2.3 7.8 4.6 3.3 7.3 1.5 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LRR_6 PF13516.6 ORY02771.1 - 1.4e-08 34.1 9.6 0.06 13.4 1.0 5.6 6 0 0 6 6 6 4 Leucine Rich repeat F-box-like PF12937.7 ORY02771.1 - 3.7e-07 29.9 0.3 2.3e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY02771.1 - 7.2e-07 29.4 7.8 0.82 10.2 0.4 5.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) MiAMP1 PF09117.10 ORY02771.1 - 0.03 14.5 1.3 2 8.7 0.4 2.9 1 1 1 2 2 2 0 MiAMP1 F-box PF00646.33 ORY02771.1 - 0.035 14.0 0.2 0.17 11.8 0.2 2.2 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 ORY02771.1 - 0.6 10.9 8.1 13 6.8 0.5 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 ORY02771.1 - 2.1 8.7 5.7 13 6.1 0.5 4.1 4 1 1 5 5 5 0 Ste50p, sterile alpha motif Cyclin PF08613.11 ORY02772.1 - 1.4e-11 45.0 0.1 2.1e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin ER_lumen_recept PF00810.18 ORY02772.1 - 0.00056 20.8 1.3 0.0028 18.5 0.4 1.9 1 1 1 2 2 2 1 ER lumen protein retaining receptor Cyclin_N PF00134.23 ORY02772.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ICL PF00463.21 ORY02774.1 - 6.7e-242 803.6 0.3 8.8e-242 803.2 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORY02774.1 - 5.4e-10 39.1 0.1 9.2e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 ORY02774.1 - 0.025 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Cyt-b5 PF00173.28 ORY02775.1 - 6.3e-22 77.5 0.0 1.1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 ORY02776.1 - 6.9e-46 156.2 0.4 2e-45 154.7 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY02776.1 - 5.1e-32 110.5 0.4 5.8e-30 103.9 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Sporozoite_P67 PF05642.11 ORY02776.1 - 0.053 11.6 6.2 0.11 10.6 6.2 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UCR_TM PF02921.14 ORY02777.1 - 2.3e-11 44.0 0.5 6.2e-11 42.6 0.5 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 ORY02777.1 - 5.8e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain GRIM-19 PF06212.12 ORY02778.1 - 6e-37 126.5 0.0 7.3e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein RRM_1 PF00076.22 ORY02779.1 - 1.4e-19 69.7 0.0 2.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY02779.1 - 5.3e-05 23.0 0.0 8.4e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif DbpA PF03880.15 ORY02779.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_7 PF16367.5 ORY02779.1 - 0.026 14.7 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif LsmAD PF06741.13 ORY02780.1 - 1.2e-28 99.4 5.8 2.7e-28 98.3 2.0 2.8 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 ORY02780.1 - 5.9e-23 80.8 0.0 1.2e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain CsgE PF10627.9 ORY02780.1 - 0.087 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Curli assembly protein CsgE PAM2 PF07145.15 ORY02780.1 - 9 6.2 11.8 4 7.3 1.6 3.3 3 0 0 3 3 3 0 Ataxin-2 C-terminal region WD40 PF00400.32 ORY02781.1 - 2.9e-29 100.7 13.2 1.6e-06 28.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02781.1 - 2.6e-10 40.5 1.4 1.1 9.7 0.0 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY02781.1 - 0.00042 19.2 1.3 0.64 8.7 0.0 3.5 2 2 1 3 3 3 3 Nup133 N terminal like IRF PF00605.17 ORY02781.1 - 0.011 16.0 0.8 0.62 10.4 0.2 2.2 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor MPC PF03650.13 ORY02782.1 - 2e-29 102.0 0.2 2.2e-29 101.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Myb_DNA-binding PF00249.31 ORY02783.1 - 2.1e-50 168.6 16.7 2e-12 47.1 0.1 5.3 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY02783.1 - 5.1e-49 164.4 16.3 3.6e-16 59.2 0.1 6.0 1 1 5 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.10 ORY02783.1 - 7.1e-12 45.4 1.7 0.013 15.5 0.0 4.1 1 1 3 4 4 4 4 SLIDE SANT_DAMP1_like PF16282.5 ORY02783.1 - 9.7e-12 44.9 9.6 0.0021 18.2 0.1 5.1 1 1 4 5 5 5 3 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 ORY02783.1 - 3.4e-11 42.9 4.1 0.022 14.6 0.0 3.8 2 1 2 4 4 4 3 Myb DNA-binding like Rap1_C PF11626.8 ORY02783.1 - 6.2e-06 26.2 8.5 0.58 10.3 1.0 4.4 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 ORY02783.1 - 0.0017 18.5 0.4 8.2 6.7 0.0 4.7 4 1 1 5 5 5 1 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 ORY02783.1 - 0.0021 18.1 3.1 5.5 7.1 0.1 4.3 4 0 0 4 4 4 2 Myb/SANT-like DNA-binding domain RRF PF01765.19 ORY02783.1 - 0.26 11.2 1.3 5.6 6.9 0.1 2.5 3 0 0 3 3 3 0 Ribosome recycling factor Asparaginase_2 PF01112.18 ORY02784.1 - 6e-112 373.6 0.2 6.9e-112 373.4 0.2 1.0 1 0 0 1 1 1 1 Asparaginase G_glu_transpept PF01019.21 ORY02784.1 - 0.031 13.1 0.3 3.4 6.3 0.3 2.1 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase PI-PLC-X PF00388.19 ORY02785.1 - 7.5e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DB_JBP1 PF18526.1 ORY02785.1 - 0.1 12.5 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Thymine dioxygenase JBP1 DNA-binding domain Histone PF00125.24 ORY02788.1 - 3.2e-52 176.4 2.7 3.5e-52 176.2 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY02788.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY02788.1 - 3e-05 24.1 0.4 4.8e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY02788.1 - 0.00018 22.1 1.1 0.00021 21.9 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY02788.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY02788.1 - 0.055 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY02788.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SET PF00856.28 ORY02789.1 - 7.9e-09 36.1 0.1 4.1e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 SET domain SAF PF08666.12 ORY02789.1 - 0.013 16.1 0.0 1.5 9.5 0.0 2.2 2 0 0 2 2 2 0 SAF domain DUF2513 PF10711.9 ORY02789.1 - 0.097 13.0 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) GTP_EFTU PF00009.27 ORY02790.1 - 3.9e-63 212.5 0.3 7.1e-63 211.7 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY02790.1 - 4.1e-39 133.1 0.1 9.9e-39 131.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ORY02790.1 - 7.6e-32 109.2 0.0 1.5e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY02790.1 - 2.7e-22 78.6 0.1 6.7e-22 77.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY02790.1 - 1.4e-11 44.6 0.1 6.5e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY02790.1 - 1.9e-07 31.0 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORY02790.1 - 5.7e-05 23.2 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.13 ORY02790.1 - 0.02 15.0 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) AIG1 PF04548.16 ORY02790.1 - 0.045 13.1 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family DUF5446 PF17522.2 ORY02790.1 - 0.27 11.4 1.9 0.64 10.2 1.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) CorA PF01544.18 ORY02791.1 - 3.5e-53 180.8 0.0 4.3e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MM_CoA_mutase PF01642.22 ORY02792.1 - 3e-241 801.4 0.1 3.5e-241 801.2 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 ORY02792.1 - 8.7e-17 61.3 0.3 2e-16 60.1 0.1 1.7 2 0 0 2 2 2 1 B12 binding domain HisG_C PF08029.11 ORY02792.1 - 0.097 12.8 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 HisG, C-terminal domain PhnI PF05861.12 ORY02792.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) HATPase_c PF02518.26 ORY02793.1 - 1.1e-30 106.4 0.2 4.9e-30 104.3 0.2 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY02793.1 - 6.4e-25 87.5 0.8 2e-24 85.9 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HAMP PF00672.25 ORY02793.1 - 1.8e-21 76.3 24.1 6.8e-07 29.6 0.0 11.3 12 2 2 14 14 12 4 HAMP domain HisKA PF00512.25 ORY02793.1 - 8.3e-17 61.0 0.4 8.3e-16 57.8 0.4 3.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 ORY02793.1 - 1.3e-08 35.0 0.0 18 5.6 0.0 7.4 8 0 0 8 8 7 0 Domain of unknown function (DUF4279) HMG_box PF00505.19 ORY02793.1 - 3.7e-06 27.3 0.0 31 5.1 0.0 6.0 6 0 0 6 6 6 0 HMG (high mobility group) box HTH_6 PF01418.17 ORY02793.1 - 7.8e-06 25.8 6.9 2.4 8.2 0.1 6.9 7 0 0 7 7 7 1 Helix-turn-helix domain, rpiR family IL32 PF15225.6 ORY02793.1 - 2.5e-05 24.6 0.7 27 5.2 0.0 7.2 7 1 1 8 8 8 0 Interleukin 32 SpoIIID PF12116.8 ORY02793.1 - 5e-05 23.3 15.1 17 5.6 0.0 8.3 8 0 0 8 8 8 0 Stage III sporulation protein D Apolipoprotein PF01442.18 ORY02793.1 - 0.0036 17.2 8.7 2.2 8.1 4.3 4.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain DUF5609 PF18429.1 ORY02793.1 - 0.015 15.1 15.5 6.4 6.6 0.1 7.2 7 0 0 7 7 7 0 Domain of unknown function (DUF5609) APG17 PF04108.12 ORY02793.1 - 0.022 13.9 19.1 0.031 13.4 3.4 5.0 1 1 0 3 3 3 0 Autophagy protein Apg17 WXG100 PF06013.12 ORY02793.1 - 0.065 13.5 18.6 1.7 8.9 0.1 8.1 7 1 1 9 9 8 0 Proteins of 100 residues with WXG Big_3_4 PF13754.6 ORY02793.1 - 0.22 11.3 4.2 14 5.5 0.1 4.5 5 0 0 5 5 3 0 Domain of unknown function DASH_Dad2 PF08654.10 ORY02793.1 - 0.23 11.9 42.5 2.7 8.4 0.8 9.1 3 2 4 9 9 9 0 DASH complex subunit Dad2 CENP-F_leu_zip PF10473.9 ORY02793.1 - 0.33 11.0 16.4 21 5.1 0.0 6.9 7 1 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.11 ORY02793.1 - 0.35 10.9 54.6 0.55 10.3 2.7 9.1 2 2 6 9 9 9 0 Apolipophorin-III precursor (apoLp-III) Myb_DNA-bind_5 PF13873.6 ORY02793.1 - 0.37 10.9 4.2 22 5.2 0.2 5.3 8 0 0 8 8 7 0 Myb/SANT-like DNA-binding domain Sec15 PF04091.12 ORY02793.1 - 0.71 9.2 6.3 0.51 9.7 3.0 2.5 2 1 0 2 2 2 0 Exocyst complex subunit Sec15-like GLE1 PF07817.13 ORY02793.1 - 1.3 8.1 17.4 7.4 5.7 0.1 5.8 4 2 2 6 6 6 0 GLE1-like protein DUF3634 PF12321.8 ORY02793.1 - 4.4 7.8 10.1 26 5.3 0.0 5.9 7 0 0 7 7 4 0 Protein of unknown function (DUF3634) WD40 PF00400.32 ORY02794.1 - 6.5e-25 86.9 13.9 6.3e-07 30.0 0.6 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02794.1 - 5.6e-07 29.8 0.3 0.42 10.9 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY02794.1 - 5.4e-05 22.0 3.7 2.6 6.6 0.1 3.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ORY02794.1 - 0.05 13.2 0.1 0.22 11.1 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain WD40 PF00400.32 ORY02795.1 - 1.8e-39 133.0 24.1 7.4e-06 26.6 0.4 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 ORY02795.1 - 1.6e-07 31.1 0.1 3.9e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORY02795.1 - 1e-06 29.0 0.5 3.3 8.1 0.0 5.8 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORY02795.1 - 8.6e-06 25.5 0.2 2.1e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORY02795.1 - 0.011 14.4 8.8 3.4 6.2 0.2 5.2 4 1 1 5 5 5 0 Nucleoporin Nup120/160 F-box_4 PF15966.5 ORY02795.1 - 0.026 14.4 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 F-box PQQ PF01011.21 ORY02795.1 - 0.028 14.4 0.4 16 5.6 0.3 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat DUF1356 PF07092.12 ORY02796.1 - 0.0011 18.3 0.3 0.0014 17.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 ORY02796.1 - 0.0055 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein Nuf2 PF03800.14 ORY02797.1 - 2.2e-42 144.5 2.0 7.8e-42 142.7 2.0 2.0 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 ORY02797.1 - 1.4e-28 99.3 20.5 1.4e-28 99.3 20.5 3.9 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain HrpB7 PF09486.10 ORY02797.1 - 0.0011 19.4 0.8 0.0011 19.4 0.8 3.5 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) Oxidored-like PF09791.9 ORY02797.1 - 0.024 14.3 0.3 0.059 13.0 0.3 1.7 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal DUF3135 PF11333.8 ORY02797.1 - 0.081 13.2 0.1 0.081 13.2 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3135) GIT_CC PF16559.5 ORY02797.1 - 2.9 7.8 17.4 0.69 9.8 0.3 3.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2968 PF11180.8 ORY02797.1 - 4.2 7.0 31.5 0.019 14.6 15.8 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF2968) FUSC PF04632.12 ORY02797.1 - 8.4 4.8 6.4 3 6.2 0.4 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family TFR_dimer PF04253.15 ORY02797.1 - 9 6.4 8.9 4.6 7.4 2.2 2.8 3 1 0 3 3 3 0 Transferrin receptor-like dimerisation domain DUF4407 PF14362.6 ORY02797.1 - 9.3 5.5 25.6 61 2.8 13.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cyclin_N PF00134.23 ORY02798.1 - 9.9e-45 151.4 2.0 1.8e-44 150.5 1.5 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY02798.1 - 4.3e-32 110.7 1.3 9.4e-32 109.6 0.5 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ago_N_1 PF18351.1 ORY02798.1 - 0.03 14.7 0.5 1.9 8.9 0.0 3.1 1 1 1 3 3 3 0 Fungal Argonaute N-terminal domain MFS_1 PF07690.16 ORY02799.1 - 7.6e-38 130.3 29.8 9.6e-38 130.0 29.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORY02800.1 - 4.1e-38 131.2 29.4 5.5e-38 130.8 29.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BAR PF03114.18 ORY02800.1 - 0.00043 20.0 0.2 0.025 14.2 0.0 2.2 2 0 0 2 2 2 2 BAR domain BAR_2 PF10455.9 ORY02800.1 - 0.0021 17.3 0.1 0.0035 16.5 0.1 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_2 PF10455.9 ORY02801.1 - 2.3e-38 132.0 0.2 4.3e-37 127.8 0.2 2.0 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORY02801.1 - 2.6e-16 60.0 0.6 7e-16 58.6 0.6 1.6 1 1 0 1 1 1 1 BAR domain Filament PF00038.21 ORY02801.1 - 0.024 14.2 0.2 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Intermediate filament protein DUF5595 PF18077.1 ORY02801.1 - 0.024 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Vps5 PF09325.10 ORY02801.1 - 0.068 12.7 0.9 7.7 6.0 0.2 2.5 3 0 0 3 3 3 0 Vps5 C terminal like LETM1 PF07766.13 ORY02802.1 - 7e-103 343.6 5.7 7e-103 343.6 5.7 1.6 2 0 0 2 2 2 1 LETM1-like protein RAP80_UIM PF18282.1 ORY02802.1 - 4.7 7.1 11.4 8.9 6.2 4.5 3.5 3 1 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif DUF4337 PF14235.6 ORY02802.1 - 4.9 7.2 11.7 0.92 9.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) GPI-anchored PF10342.9 ORY02804.1 - 2.7e-16 60.1 0.2 2.7e-16 60.1 0.2 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORY02805.1 - 1.4e-16 61.0 0.2 1.4e-16 61.0 0.2 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORY02806.1 - 9.1e-17 61.6 0.2 1.7e-16 60.7 0.2 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.18 ORY02807.1 - 2.3e-30 105.6 2.2 5.8e-30 104.2 0.2 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY02807.1 - 9.9e-12 44.8 10.5 1.7e-11 44.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY02808.1 - 3.6e-22 78.8 26.7 5e-12 45.4 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.12 ORY02810.1 - 8.9e-12 45.5 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02810.1 - 1.2e-09 38.8 0.0 2.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02810.1 - 3.4e-07 30.2 0.0 5.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ORY02810.1 - 2.8e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 ORY02810.1 - 9.6e-05 22.3 0.0 0.00015 21.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY02810.1 - 0.00031 21.4 0.0 0.00078 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Svf1_C PF17187.4 ORY02810.1 - 0.094 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain 2OG-FeII_Oxy_2 PF13532.6 ORY02811.1 - 6.1e-35 121.2 0.0 9e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GPI-anchored PF10342.9 ORY02812.1 - 3.6e-16 59.7 1.7 3.6e-16 59.7 1.7 1.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORY02813.1 - 4.9e-14 52.8 0.2 4.9e-14 52.8 0.2 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.9 ORY02813.1 - 6 5.3 6.1 6.6 5.1 6.1 1.0 1 0 0 1 1 1 0 Macoilin family GPI-anchored PF10342.9 ORY02814.1 - 2.1e-14 54.1 0.1 2.1e-14 54.1 0.1 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribonuc_L-PSP PF01042.21 ORY02815.1 - 5e-45 152.4 0.2 5.6e-45 152.2 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2791 PF10923.8 ORY02815.1 - 0.035 13.0 0.0 0.041 12.7 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NFACT-R_1 PF05670.13 ORY02816.1 - 1.4e-42 144.8 0.0 2.2e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain YcgL PF05166.13 ORY02816.1 - 0.069 13.5 0.1 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 YcgL domain SopE_GEF PF07487.13 ORY02816.1 - 0.85 9.7 6.2 4.7 7.3 0.3 3.0 1 1 1 2 2 2 0 SopE GEF domain DUF1764 PF08576.10 ORY02816.1 - 2.3 9.2 12.2 4.2 8.3 12.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_L5_C PF00673.21 ORY02817.1 - 1e-22 80.1 0.0 1.4e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY02817.1 - 1e-20 73.8 0.0 6.8e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 ORY02817.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY02818.1 - 5.3e-45 153.3 0.8 7.7e-45 152.8 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY02818.1 - 1.5e-26 93.3 0.0 4.2e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY02818.1 - 5.2e-22 77.9 0.0 9.8e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY02818.1 - 5.1e-20 72.1 0.0 9.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NDUF_B7 PF05676.13 ORY02819.1 - 1.4e-31 108.0 3.7 1.9e-31 107.5 3.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ORY02819.1 - 0.018 15.1 2.8 0.027 14.5 2.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NPIP PF06409.11 ORY02819.1 - 0.11 11.5 1.1 2.6 7.0 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) Glyco_hydro_47 PF01532.20 ORY02820.1 - 1.1e-156 522.3 0.1 1.3e-156 522.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LAGLIDADG_2 PF03161.13 ORY02821.1 - 0.028 14.4 0.8 0.13 12.3 0.1 1.9 1 1 0 2 2 2 0 LAGLIDADG DNA endonuclease family DUF4695 PF15766.5 ORY02821.1 - 0.086 13.1 1.1 0.12 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF612 PF04747.12 ORY02821.1 - 0.14 11.3 4.7 0.16 11.1 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 DUF4375 PF14300.6 ORY02821.1 - 0.19 12.0 9.3 0.42 10.9 8.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) RRF PF01765.19 ORY02821.1 - 0.22 11.5 5.8 0.4 10.6 5.8 1.5 1 1 0 1 1 1 0 Ribosome recycling factor DUF5344 PF17279.2 ORY02821.1 - 0.32 11.6 4.7 1.5 9.5 0.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5344) RRM_1 PF00076.22 ORY02822.1 - 5.9e-42 141.4 0.0 7.3e-20 70.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY02822.1 - 2e-05 24.5 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY02822.1 - 4.2e-05 23.3 0.0 0.049 13.5 0.0 2.8 2 2 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY02822.1 - 0.0016 18.5 0.0 0.41 10.8 0.0 2.5 2 2 0 2 2 2 2 RNA recognition motif DUF1866 PF08952.11 ORY02822.1 - 0.13 12.1 0.0 2.4 8.0 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1866) Abhydrolase_1 PF00561.20 ORY02823.1 - 6.2e-14 52.3 0.0 3.8e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY02823.1 - 9.4e-08 31.6 0.0 1.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 ORY02823.1 - 0.047 12.4 0.1 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 PS-10 peptidase S37 PRO8NT PF08082.11 ORY02824.1 - 0.031 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain MAP65_ASE1 PF03999.12 ORY02824.1 - 8.1 5.0 5.9 12 4.4 0.4 2.0 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Arf PF00025.21 ORY02825.1 - 2e-18 66.5 0.8 1.3e-10 41.1 0.2 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY02825.1 - 4.6e-06 26.9 0.0 6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY02825.1 - 0.00014 21.5 0.0 0.00018 21.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY02825.1 - 0.079 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MIP PF00230.20 ORY02826.1 - 2.1e-56 191.2 11.3 2.5e-56 190.9 11.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein dDENN PF03455.19 ORY02826.1 - 0.12 12.3 0.5 15 5.7 0.1 2.3 2 0 0 2 2 2 0 dDENN domain Velvet PF11754.8 ORY02827.1 - 4.9e-36 124.9 0.4 5.6e-36 124.8 0.4 1.0 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.16 ORY02828.1 - 2.7e-32 112.1 27.2 5.2e-24 84.8 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bax1-I PF01027.20 ORY02828.1 - 0.16 11.8 25.0 0.04 13.8 11.9 2.3 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 UPF0182 PF03699.13 ORY02828.1 - 0.22 9.6 1.9 0.25 9.4 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Lipase_GDSL_2 PF13472.6 ORY02869.1 - 4.9e-05 23.8 0.0 7.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY02869.1 - 0.00013 22.0 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Actin PF00022.19 ORY02870.1 - 3.6e-40 137.8 0.0 2.1e-39 135.3 0.0 2.2 1 1 0 1 1 1 1 Actin DUF3587 PF12132.8 ORY02871.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3587) Pkinase PF00069.25 ORY02872.1 - 5.3e-54 183.3 0.0 2e-53 181.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY02872.1 - 3.6e-19 69.1 0.0 1.7e-17 63.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY02872.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.27 ORY02873.1 - 9.9e-39 132.6 0.0 1.5e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Cyclin PF08613.11 ORY02874.1 - 2.5e-10 41.0 0.0 3.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY02874.1 - 1.5e-05 24.7 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-H2C2_2 PF13465.6 ORY02875.1 - 1.2e-14 53.9 10.1 1.9e-09 37.5 0.4 3.8 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY02875.1 - 5.8e-14 51.7 23.0 5.5e-05 23.4 0.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY02875.1 - 4e-10 39.6 19.5 0.001 19.7 0.1 3.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY02875.1 - 4.3e-06 26.6 14.9 6.8e-05 22.7 0.0 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 ORY02875.1 - 5.6e-05 23.4 18.3 0.039 14.4 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger of C2H2 type BolA PF01722.18 ORY02875.1 - 0.0013 19.0 1.3 1 9.7 2.5 2.0 1 1 1 2 2 2 2 BolA-like protein Baculo_IE-1 PF05290.11 ORY02875.1 - 0.0077 16.2 1.4 0.35 10.8 0.2 2.2 1 1 1 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-C2H2_jaz PF12171.8 ORY02875.1 - 0.0083 16.4 14.8 0.58 10.5 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY02875.1 - 0.0093 15.8 6.0 0.023 14.6 0.1 2.5 3 0 0 3 3 2 1 zinc-finger of a C2HC-type Zf_RING PF16744.5 ORY02875.1 - 0.015 15.4 5.3 0.69 10.1 0.2 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger zinc-ribbons_6 PF07191.12 ORY02875.1 - 0.016 15.2 3.6 0.85 9.6 0.9 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-C2HE PF16278.5 ORY02875.1 - 0.02 15.3 10.8 3.7 8.1 8.0 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 ORY02875.1 - 0.021 14.9 5.6 8.7 6.5 0.1 3.0 1 1 2 3 3 3 0 Zic proteins zinc finger domain Zn-ribbon_8 PF09723.10 ORY02875.1 - 0.027 14.6 2.9 5.6 7.2 0.0 2.5 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 ORY02875.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-CCHC_2 PF13696.6 ORY02875.1 - 0.14 12.0 9.7 3.7 7.5 0.2 2.6 2 1 0 2 2 2 0 Zinc knuckle C1_2 PF03107.16 ORY02875.1 - 0.19 12.1 9.8 4.7 7.6 9.8 2.2 1 1 0 1 1 1 0 C1 domain zf-C2H2_2 PF12756.7 ORY02875.1 - 0.2 12.0 9.4 3.9 7.9 5.7 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 ORY02875.1 - 0.24 11.1 12.2 0.47 10.1 2.3 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_4 PF07975.12 ORY02875.1 - 0.24 11.7 9.6 0.1 12.9 3.6 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_8 PF15909.5 ORY02875.1 - 0.66 10.3 7.5 0.39 11.0 4.8 1.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon GAGA PF09237.11 ORY02875.1 - 3.9 7.4 10.0 1.3 8.9 3.9 2.3 1 1 1 2 2 2 0 GAGA factor TPT PF03151.16 ORY02876.1 - 9.9e-65 218.7 27.9 1.2e-64 218.5 27.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY02876.1 - 7.5e-14 52.1 38.3 5.6e-07 29.8 15.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY02876.1 - 6.2e-10 38.8 31.5 9e-10 38.2 31.5 1.2 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 ORY02876.1 - 0.026 15.2 1.2 0.026 15.2 1.2 3.4 2 1 1 3 3 3 0 Small Multidrug Resistance protein Ank_4 PF13637.6 ORY02877.1 - 2.2e-11 44.0 0.1 2.7e-06 27.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY02877.1 - 7.8e-11 42.4 0.0 1.3e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY02877.1 - 9.3e-07 29.0 0.0 5.6e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY02877.1 - 1.1e-05 25.6 0.1 0.00029 21.2 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 ORY02877.1 - 0.00051 20.3 0.0 0.037 14.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ctr PF04145.15 ORY02878.1 - 3.1e-19 70.1 12.1 1.1e-18 68.3 12.1 1.7 1 1 0 1 1 1 1 Ctr copper transporter family HemY_N PF07219.13 ORY02878.1 - 3 8.1 6.8 0.68 10.2 0.6 2.0 2 0 0 2 2 2 0 HemY protein N-terminus YtpI PF14007.6 ORY02878.1 - 4 7.7 9.4 0.88 9.8 0.7 2.1 1 1 1 2 2 2 0 YtpI-like protein Plus-3 PF03126.18 ORY02879.1 - 1.4e-32 112.4 0.1 5.7e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain SPX PF03105.19 ORY02880.1 - 8.4e-38 131.3 6.5 4e-37 129.0 6.5 1.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 ORY02880.1 - 2.9e-08 33.4 7.8 5.4e-08 32.6 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY02880.1 - 5.2e-08 32.9 10.6 1.3e-07 31.6 8.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY02880.1 - 3.7e-07 30.1 6.4 1.2e-06 28.5 6.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY02880.1 - 1.1e-06 28.4 9.4 1.1e-06 28.4 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY02880.1 - 1.2e-06 28.7 10.2 1.2e-06 28.7 10.2 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY02880.1 - 6.8e-06 25.8 10.0 6.8e-06 25.8 10.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY02880.1 - 4.4e-05 23.3 11.1 0.00026 20.9 11.4 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY02880.1 - 0.0014 18.4 9.2 0.0058 16.5 9.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY02880.1 - 0.024 14.4 4.2 0.024 14.4 4.2 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 ORY02880.1 - 0.035 14.2 1.1 0.071 13.2 1.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.6 ORY02880.1 - 0.048 13.5 3.1 0.12 12.3 3.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY02880.1 - 0.049 13.9 8.7 0.15 12.3 8.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 ORY02880.1 - 0.073 13.2 4.1 0.14 12.3 4.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Mito_carr PF00153.27 ORY02881.1 - 7.4e-29 99.5 1.4 1.1e-12 47.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY02881.1 - 0.00028 20.1 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease PseudoU_synth_2 PF00849.22 ORY02882.1 - 3e-25 89.2 0.0 4.2e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF423 PF04241.15 ORY02884.1 - 1.3e-25 89.4 0.3 1.7e-25 89.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Transp_cyt_pur PF02133.15 ORY02885.1 - 2.5e-113 379.2 35.6 2.8e-113 379.0 35.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glycos_transf_1 PF00534.20 ORY02886.1 - 1.4e-23 83.3 0.0 2.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY02886.1 - 3.2e-14 53.5 0.1 5e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORY02886.1 - 1e-08 35.5 0.0 2.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 MRP-S35 PF10246.9 ORY02886.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 eIF-3c_N PF05470.12 ORY02888.1 - 1.7e-209 697.0 16.7 3.1e-209 696.2 16.7 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 ORY02888.1 - 1.7e-15 57.4 0.1 1.1e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 PCI domain GDPD PF03009.17 ORY02888.1 - 0.017 14.9 0.2 0.25 11.0 0.2 2.6 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family TFR_dimer PF04253.15 ORY02888.1 - 0.018 15.1 1.3 0.6 10.2 0.0 3.6 4 0 0 4 4 4 0 Transferrin receptor-like dimerisation domain Band_7_1 PF13421.6 ORY02888.1 - 0.16 11.7 0.2 0.47 10.1 0.1 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family Transp_cyt_pur PF02133.15 ORY02889.1 - 2.6e-113 379.1 35.6 2.9e-113 378.9 35.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 ORY02890.1 - 2.6e-113 379.1 35.6 2.9e-113 378.9 35.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Oxidored_FMN PF00724.20 ORY02891.1 - 1.5e-99 333.6 0.0 2.1e-99 333.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ECR1_N PF14382.6 ORY02892.1 - 1.6e-15 56.6 0.1 3.2e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 ORY02892.1 - 9.7e-13 48.3 0.1 2.2e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 KH domain EF-G-binding_N PF07299.11 ORY02892.1 - 0.14 12.7 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal NUDIX PF00293.28 ORY02893.1 - 0.009 16.1 0.2 0.74 9.9 0.1 3.1 2 1 0 2 2 2 1 NUDIX domain GPR_Gpa2_C PF11970.8 ORY02895.1 - 8.7e-05 22.5 0.3 0.00026 21.0 0.3 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1189 PF06691.11 ORY02895.1 - 0.025 14.2 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Cyclin PF08613.11 ORY02896.1 - 3.2e-38 131.6 0.3 5.9e-38 130.8 0.3 1.4 1 0 0 1 1 1 1 Cyclin Fasciclin PF02469.22 ORY02897.1 - 1.1e-42 145.3 2.8 1.4e-21 77.1 0.2 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 ORY02898.1 - 9.8e-51 171.3 3.9 4.9e-28 97.9 1.1 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 ORY02898.1 - 0.049 13.8 1.8 3.4 7.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 Fasciclin PF02469.22 ORY02899.1 - 6.1e-51 172.0 3.5 4.3e-28 98.1 0.9 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 ORY02899.1 - 0.14 12.4 3.6 3 8.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Fasciclin PF02469.22 ORY02900.1 - 1.1e-51 174.4 3.5 8.4e-29 100.4 0.8 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 ORY02900.1 - 0.079 13.1 2.7 3 8.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Ntox10 PF15520.6 ORY02900.1 - 0.6 9.9 8.7 0.096 12.5 0.5 2.8 2 1 1 3 3 3 0 Novel toxin 10 Fasciclin PF02469.22 ORY02901.1 - 9.3e-51 171.4 3.5 5.3e-28 97.8 0.9 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF1206 PF06724.11 ORY02901.1 - 0.036 14.1 0.7 0.093 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF211 PF02680.14 ORY02901.1 - 0.05 13.8 1.7 3.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 Fasciclin PF02469.22 ORY02902.1 - 1.4e-25 90.0 4.8 3.8e-17 62.7 0.9 2.5 2 1 1 3 3 3 2 Fasciclin domain DUF211 PF02680.14 ORY02902.1 - 0.086 13.0 1.7 2 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 ORF_2_N PF18492.1 ORY02902.1 - 0.22 11.8 4.6 5.3 7.3 0.2 2.5 2 0 0 2 2 2 0 Open reading frame 2 N-terminal domain Methyltransf_23 PF13489.6 ORY02903.1 - 8.3e-16 58.3 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY02903.1 - 1.1e-12 48.5 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY02903.1 - 3.7e-09 37.2 0.0 5.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY02903.1 - 1.4e-07 31.4 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY02903.1 - 2.4e-07 31.4 0.0 4.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY02903.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family E1-E2_ATPase PF00122.20 ORY02904.1 - 3.3e-27 95.2 0.0 9.9e-27 93.6 0.0 1.9 1 1 1 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY02904.1 - 2.5e-10 41.0 0.3 2.4e-05 24.7 0.1 3.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY02904.1 - 7.1e-05 22.4 1.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY02904.1 - 0.0046 17.0 0.0 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_4 PF12146.8 ORY02905.1 - 1.5e-17 63.6 0.2 1.4e-16 60.5 0.2 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY02905.1 - 7.6e-17 61.8 1.0 4.1e-13 49.6 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY02905.1 - 3.9e-09 37.4 0.1 9.3e-09 36.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 ORY02905.1 - 4.9e-05 23.2 0.0 7.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 ORY02905.1 - 0.00029 20.8 0.2 0.00081 19.3 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY02905.1 - 0.00037 20.7 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 ORY02905.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Say1_Mug180 PF10340.9 ORY02905.1 - 0.0025 16.7 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 ORY02905.1 - 0.0054 16.6 0.0 0.36 10.6 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Cutinase PF01083.22 ORY02905.1 - 0.012 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.8 ORY02905.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ORY02905.1 - 0.021 14.5 0.1 0.054 13.2 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein BAAT_C PF08840.11 ORY02905.1 - 0.022 14.7 0.0 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 ORY02905.1 - 0.032 13.9 0.1 0.16 11.6 0.1 2.1 1 1 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 ORY02905.1 - 0.033 14.1 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 ORY02905.1 - 0.098 12.4 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY02905.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein CLP_protease PF00574.23 ORY02905.1 - 0.11 12.3 0.0 1.8 8.4 0.0 2.1 1 1 1 2 2 2 0 Clp protease DUF818 PF05677.12 ORY02905.1 - 0.17 10.8 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) RRM_1 PF00076.22 ORY02906.1 - 4.8e-30 103.2 1.5 1.8e-10 40.5 0.3 4.6 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 ORY02906.1 - 3.4e-08 33.5 0.0 0.0012 18.7 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 ORY02906.1 - 9.3e-08 31.8 0.0 0.021 14.7 0.1 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY02906.1 - 0.016 15.3 0.1 0.31 11.1 0.1 2.6 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 ORY02906.1 - 0.021 14.8 0.0 21 5.2 0.0 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY02906.1 - 0.1 12.7 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif LRR_8 PF13855.6 ORY02907.1 - 9.1e-52 172.7 75.6 1e-11 44.4 1.2 10.7 7 3 6 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 ORY02907.1 - 1.2e-47 159.0 80.6 1.4e-06 28.5 1.1 12.7 11 2 1 12 12 12 11 Leucine Rich repeats (2 copies) PP2C PF00481.21 ORY02907.1 - 7.8e-45 153.5 0.0 1.3e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 ORY02907.1 - 3.2e-28 98.6 0.0 6.3e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 ORY02907.1 - 4.3e-07 29.6 73.9 0.54 11.0 0.5 18.1 18 2 0 18 18 18 3 Leucine Rich Repeat LRR_9 PF14580.6 ORY02907.1 - 1.2e-05 24.8 28.0 0.0061 16.1 3.4 5.5 3 1 5 8 8 8 5 Leucine-rich repeat DUF1338 PF07063.13 ORY02907.1 - 0.068 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Kinesin PF00225.23 ORY02908.1 - 2.7e-106 355.3 0.2 5.2e-106 354.3 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 ORY02908.1 - 6.4e-44 150.3 0.3 1.8e-43 148.8 0.3 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 ORY02908.1 - 7.1e-42 143.6 2.7 3.1e-35 122.0 0.2 4.4 4 1 1 5 5 5 2 Kinesin-associated Microtub_bd PF16796.5 ORY02908.1 - 1.6e-21 76.8 0.0 6.2e-21 74.9 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 ORY02908.1 - 1.1e-15 58.1 0.3 7.9e-15 55.3 0.2 2.6 3 0 0 3 3 3 1 PH domain KIF1B PF12423.8 ORY02908.1 - 7.5e-08 32.7 0.2 2.6e-07 30.9 0.2 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 ORY02908.1 - 2.9e-05 24.3 0.2 0.00017 21.8 0.0 2.4 3 0 0 3 3 3 1 FHA domain PH_9 PF15410.6 ORY02908.1 - 0.0014 19.0 0.4 0.0014 19.0 0.4 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 ORY02908.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PH_TFIIH PF08567.11 ORY02908.1 - 0.14 12.5 0.8 7.6 6.9 0.0 3.0 3 0 0 3 3 2 0 TFIIH p62 subunit, N-terminal domain PilJ PF13675.6 ORY02908.1 - 0.67 10.0 5.9 15 5.6 1.1 3.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Selenoprotein_S PF06936.11 ORY02908.1 - 4.4 7.1 7.0 10 5.9 3.8 2.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) Velvet PF11754.8 ORY02909.1 - 6.5e-38 131.1 0.0 8.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORY02910.1 - 3.5e-52 177.8 2.8 5.1e-36 124.9 0.2 2.0 1 1 1 2 2 2 2 Velvet factor TPR_2 PF07719.17 ORY02911.1 - 3.6e-08 32.9 1.8 0.0019 18.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY02911.1 - 4.4e-05 23.1 2.2 0.14 12.1 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY02911.1 - 0.00011 21.7 1.8 0.096 12.4 0.8 2.5 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 ORY02911.1 - 0.003 17.8 0.8 0.011 16.0 0.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY02911.1 - 0.0095 16.6 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02911.1 - 0.018 15.8 0.2 0.88 10.6 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02911.1 - 0.033 14.4 3.0 2.8 8.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 ORY02911.1 - 0.034 14.2 1.0 0.19 11.8 0.2 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 ORY02911.1 - 0.034 14.6 0.5 0.066 13.7 0.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat LRIF1 PF15741.5 ORY02911.1 - 4.8 5.6 21.6 7.2 5.0 21.6 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 SNF5 PF04855.12 ORY02912.1 - 1.6e-62 211.4 0.1 3.4e-61 207.1 0.1 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 XLF PF09302.11 ORY02912.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Rab_bind PF16704.5 ORY02912.1 - 0.13 12.3 0.5 5.3 7.2 0.5 2.3 2 0 0 2 2 2 0 Rab binding domain GTP_EFTU PF00009.27 ORY02913.1 - 5.5e-35 120.7 0.0 7e-34 117.1 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY02913.1 - 4.1e-19 68.6 0.1 1.7e-18 66.7 0.1 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 ORY02913.1 - 2.4e-14 53.5 12.8 1e-09 38.7 0.1 4.3 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 ORY02913.1 - 1.1e-11 44.4 0.1 3.9e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 ORY02913.1 - 7.1e-07 29.3 0.1 1.2e-05 25.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORY02913.1 - 0.00022 21.1 2.6 0.00026 20.8 0.0 2.6 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein Roc PF08477.13 ORY02913.1 - 0.00032 20.9 0.0 0.00097 19.3 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORY02913.1 - 0.014 15.7 0.2 0.34 11.2 0.2 2.9 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 ORY02913.1 - 0.15 11.6 1.8 0.98 9.0 0.0 2.8 2 1 0 2 2 2 0 Ras family ketoacyl-synt PF00109.26 ORY02914.1 - 2.1e-58 197.9 1.0 3.6e-58 197.1 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY02914.1 - 5.1e-40 136.2 0.6 9.8e-40 135.3 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.18 ORY02914.1 - 0.00011 21.8 0.6 0.00054 19.6 0.4 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 ORY02914.1 - 0.00017 21.1 0.9 0.0004 19.8 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Peptidase_M49 PF03571.15 ORY02915.1 - 2e-241 802.2 0.0 4.1e-241 801.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M49 TRA-1_regulated PF02343.16 ORY02915.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 GST_N_3 PF13417.6 ORY02916.1 - 2.6e-13 50.1 0.0 5.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY02916.1 - 1.6e-12 47.5 0.0 9.5e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY02916.1 - 4e-11 43.0 0.0 1e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY02916.1 - 3.2e-10 39.9 0.0 9.2e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY02916.1 - 4.3e-09 36.6 0.0 8.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY02916.1 - 1.4e-06 28.4 0.1 3.5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY02916.1 - 1.6e-06 28.7 0.0 3.8e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY02916.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain DUF22 PF01629.16 ORY02916.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 DHHC PF01529.20 ORY02973.1 - 5.3e-25 88.1 4.6 7.2e-25 87.6 4.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cation_efflux PF01545.21 ORY02973.1 - 0.086 12.6 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Cation efflux family DUF3421 PF11901.8 ORY02974.1 - 2.6e-28 98.3 0.1 5.8e-17 61.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) FKBP_C PF00254.28 ORY02975.1 - 5.7e-35 119.5 0.0 6.6e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WD40 PF00400.32 ORY02976.1 - 2.4e-17 63.0 5.4 2.2e-08 34.6 0.5 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02976.1 - 5.6e-15 55.4 0.1 0.003 17.8 0.0 5.9 3 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY02976.1 - 0.004 17.0 0.2 0.52 10.2 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORY02976.1 - 0.011 13.8 0.3 1.1 7.1 0.0 2.4 2 1 0 2 2 2 0 IKI3 family bZIP_1 PF00170.21 ORY02977.1 - 4.9e-09 36.1 12.3 9.2e-09 35.3 12.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY02977.1 - 1.6e-06 28.1 8.4 1.6e-06 28.1 8.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper YabA PF06156.13 ORY02977.1 - 4.5e-06 27.2 1.4 9.9e-06 26.1 1.4 1.6 1 0 0 1 1 1 1 Initiation control protein YabA bZIP_Maf PF03131.17 ORY02977.1 - 0.00032 21.2 7.0 0.00053 20.4 7.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SOGA PF11365.8 ORY02977.1 - 0.00036 21.6 1.4 0.0021 19.2 0.9 2.2 2 0 0 2 2 2 1 Protein SOGA DUF812 PF05667.11 ORY02977.1 - 0.00089 18.3 1.5 0.0011 18.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HMMR_N PF15905.5 ORY02977.1 - 0.0024 17.4 4.9 0.0033 17.0 4.9 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 ORY02977.1 - 0.0081 16.0 5.4 0.01 15.6 5.4 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc7 PF08317.11 ORY02977.1 - 0.0089 14.9 4.2 0.012 14.5 4.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Chibby PF14645.6 ORY02977.1 - 0.02 15.3 1.7 0.042 14.3 1.7 1.4 1 0 0 1 1 1 0 Chibby family Herpes_UL6 PF01763.16 ORY02977.1 - 0.029 12.9 2.6 0.037 12.5 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FlxA PF14282.6 ORY02977.1 - 0.033 14.2 4.1 0.033 14.2 2.3 1.9 1 1 1 2 2 2 0 FlxA-like protein Fez1 PF06818.15 ORY02977.1 - 0.041 14.3 5.2 0.058 13.9 5.2 1.2 1 0 0 1 1 1 0 Fez1 DUF1515 PF07439.11 ORY02977.1 - 0.046 13.8 0.5 0.079 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) LCD1 PF09798.9 ORY02977.1 - 0.046 12.2 5.3 0.058 11.9 5.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CC2-LZ PF16516.5 ORY02977.1 - 0.049 14.0 4.8 0.085 13.2 4.8 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LPP PF04728.13 ORY02977.1 - 0.062 13.7 0.6 0.27 11.7 0.3 2.2 2 0 0 2 2 1 0 Lipoprotein leucine-zipper EMP24_GP25L PF01105.24 ORY02977.1 - 0.13 12.2 4.3 0.21 11.5 4.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 ORY02977.1 - 0.13 12.4 4.9 0.2 11.7 4.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 ORY02977.1 - 0.19 11.1 1.0 0.25 10.7 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trimer_CC PF08954.11 ORY02977.1 - 0.34 10.5 3.5 3.2 7.4 0.9 2.7 1 1 1 2 2 2 0 Trimerisation motif Lectin_N PF03954.14 ORY02977.1 - 0.46 10.2 2.3 0.89 9.3 1.8 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CENP-H PF05837.12 ORY02977.1 - 0.54 10.7 6.3 0.47 10.9 5.0 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 ORY02977.1 - 0.93 9.9 8.1 11 6.4 8.1 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 ORY02977.1 - 1.2 9.7 6.8 2.6 8.6 6.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 ORY02977.1 - 1.2 6.9 4.8 1.6 6.6 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Urm1 PF09138.11 ORY02978.1 - 2.5e-37 127.1 0.2 2.8e-37 127.0 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 ORY02978.1 - 1.9e-06 28.4 0.4 2.4e-06 28.1 0.4 1.1 1 0 0 1 1 1 1 ThiS family adh_short_C2 PF13561.6 ORY02979.1 - 7.9e-60 202.3 1.5 9.7e-60 202.0 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY02979.1 - 7.9e-55 185.3 2.1 9.2e-55 185.1 2.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY02979.1 - 1.1e-21 77.6 0.5 1.4e-21 77.2 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY02979.1 - 0.00019 21.0 0.8 0.00088 18.8 0.5 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY02979.1 - 0.00026 20.2 0.2 0.00038 19.7 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY02979.1 - 0.017 14.7 0.3 0.017 14.7 0.3 1.8 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 ORY02979.1 - 0.017 15.0 0.2 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Flagellin_N PF00669.20 ORY02979.1 - 0.026 14.6 0.2 0.052 13.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region 3Beta_HSD PF01073.19 ORY02979.1 - 0.031 13.3 0.9 0.043 12.8 0.9 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 ORY02979.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 ORY02979.1 - 0.15 11.2 0.2 0.3 10.2 0.2 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain ACT_7 PF13840.6 ORY02979.1 - 0.16 11.8 0.5 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 ACT domain zf-C4_Topoisom PF01396.19 ORY02980.1 - 0.00093 18.9 1.8 0.0017 18.1 1.8 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Ribosomal_S13 PF00416.22 ORY02981.1 - 2.2e-56 189.8 2.5 2.5e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORY02981.1 - 0.0058 15.4 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 ORY02981.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP28 PF10252.9 ORY02981.1 - 0.12 12.8 0.4 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 HAUS6_N PF14661.6 ORY02982.1 - 2.1e-35 122.4 2.5 2.1e-35 122.4 2.5 3.4 3 1 1 4 4 4 1 HAUS augmin-like complex subunit 6 N-terminus TPR_2 PF07719.17 ORY02982.1 - 1.2e-24 84.4 24.4 0.0025 17.8 0.0 12.1 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY02982.1 - 1.5e-21 76.7 14.0 0.00014 22.3 1.5 9.1 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORY02982.1 - 1.7e-20 71.9 22.6 0.0051 16.6 0.0 11.1 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY02982.1 - 1.5e-14 52.9 24.7 0.064 13.5 0.0 10.8 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY02982.1 - 3.5e-13 49.2 12.0 0.0024 18.6 0.1 9.7 7 2 5 12 12 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02982.1 - 4.1e-13 49.4 14.2 0.00043 20.5 0.3 7.7 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY02982.1 - 2.4e-12 47.3 1.9 9.7e-05 22.9 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY02982.1 - 4.9e-11 41.8 13.9 0.0097 15.9 0.0 8.5 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY02982.1 - 1.4e-09 37.9 14.9 1.6 9.6 0.0 10.4 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY02982.1 - 1.8e-09 37.1 12.8 0.34 10.6 0.0 8.0 7 1 1 8 8 8 3 TPR repeat TPR_9 PF13371.6 ORY02982.1 - 6.8e-09 35.7 1.2 0.65 10.2 0.0 6.4 4 2 4 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY02982.1 - 1.6e-07 31.4 3.8 0.34 11.2 0.0 5.3 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORY02982.1 - 6.9e-06 26.1 7.2 0.55 10.7 0.0 8.4 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY02982.1 - 0.00025 20.4 3.8 0.83 8.8 0.1 4.9 4 2 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 ORY02982.1 - 0.00039 20.2 3.5 4.8 6.8 0.0 4.7 3 1 1 4 4 4 1 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 ORY02982.1 - 0.0014 18.7 6.2 0.0048 16.9 0.5 3.5 3 0 0 3 3 2 1 Mad3/BUB1 homology region 1 TPR_5 PF12688.7 ORY02982.1 - 0.012 15.8 0.1 0.63 10.3 0.1 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_20 PF14561.6 ORY02982.1 - 0.016 15.5 11.8 0.26 11.6 0.7 6.0 8 0 0 8 8 5 0 Tetratricopeptide repeat PPR PF01535.20 ORY02982.1 - 0.046 14.0 4.0 33 5.0 0.2 5.4 7 0 0 7 7 5 0 PPR repeat MIT PF04212.18 ORY02982.1 - 1.1 9.3 10.0 6.5 6.9 0.1 5.9 7 0 0 7 7 5 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.9 ORY02982.1 - 1.9 8.2 4.9 27 4.4 0.2 3.4 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FANCI_S3 PF14677.6 ORY02982.1 - 3.2 7.4 6.1 0.64 9.7 1.6 2.0 2 0 0 2 2 2 0 FANCI solenoid 3 RTA1 PF04479.13 ORY02983.1 - 0.0033 17.1 6.1 0.0033 17.1 6.1 2.2 2 0 0 2 2 2 1 RTA1 like protein DUF4131 PF13567.6 ORY02983.1 - 0.034 13.8 0.5 0.034 13.8 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4149 PF13664.6 ORY02983.1 - 0.17 12.2 14.3 0.67 10.3 3.7 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Spo7 PF03907.13 ORY02983.1 - 7.2 6.0 8.3 1.4 8.4 2.5 2.4 1 1 1 2 2 2 0 Spo7-like protein DnaJ PF00226.31 ORY02984.1 - 2.5e-21 75.6 1.4 5e-21 74.6 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 ORY02984.1 - 1.1e-05 25.6 0.8 1.9e-05 24.9 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF4441 PF14536.6 ORY02984.1 - 0.012 15.8 0.5 0.027 14.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) DUF2933 PF11666.8 ORY02984.1 - 0.19 11.8 1.8 0.42 10.7 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) QCR10 PF09796.9 ORY02985.1 - 3.2e-15 55.9 0.1 3.7e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TAT_signal PF10518.9 ORY02985.1 - 0.26 11.2 2.6 0.44 10.5 2.6 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Ribosomal_S19 PF00203.21 ORY02986.1 - 8e-28 96.2 0.0 9.1e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Epimerase PF01370.21 ORY02988.1 - 1.1e-52 178.9 0.0 1.8e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY02988.1 - 6.6e-15 55.3 0.0 1.5e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY02988.1 - 1.2e-05 24.6 0.1 0.00015 21.0 0.1 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY02988.1 - 8.6e-05 21.8 0.0 0.00018 20.7 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY02988.1 - 0.061 12.3 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L19e PF01280.20 ORY02989.1 - 1.5e-64 216.4 10.3 1.5e-64 216.4 10.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e PPR_2 PF13041.6 ORY02990.1 - 4.2e-86 283.0 13.8 1.3e-16 60.5 0.0 13.1 5 4 7 13 13 13 11 PPR repeat family PPR PF01535.20 ORY02990.1 - 2.8e-70 227.8 11.8 2.3e-08 33.7 0.1 15.8 16 0 0 16 16 16 11 PPR repeat PPR_1 PF12854.7 ORY02990.1 - 2.5e-60 199.9 1.6 1.8e-09 37.2 0.0 13.3 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.6 ORY02990.1 - 5.2e-60 199.4 10.8 6.1e-14 51.8 0.0 10.3 5 2 7 12 12 12 9 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY02990.1 - 1.3e-28 99.8 6.8 1.8e-09 37.3 0.0 5.7 2 2 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORY02990.1 - 5e-09 36.2 0.1 5.3 8.1 0.0 7.9 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY02990.1 - 1.4e-05 25.5 5.9 7.9 7.1 0.2 6.3 4 3 2 6 6 6 1 Tetratricopeptide repeat ATP13 PF12921.7 ORY02990.1 - 1.8e-05 24.6 5.6 7.8 6.4 0.0 7.5 3 3 5 8 8 8 1 Mitochondrial ATPase expression Clathrin PF00637.20 ORY02990.1 - 3.1e-05 23.9 7.5 2.2 8.2 0.0 5.8 5 2 1 6 6 6 2 Region in Clathrin and VPS TPR_7 PF13176.6 ORY02990.1 - 3.4e-05 23.6 0.2 0.42 10.8 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY02990.1 - 4.4e-05 22.5 4.4 0.037 12.9 0.2 3.8 2 2 1 3 3 3 3 Mitochondrial 28S ribosomal protein S27 TPR_1 PF00515.28 ORY02990.1 - 0.00059 19.5 1.8 6.6 6.7 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat RPM2 PF08579.11 ORY02990.1 - 0.0023 18.3 11.5 0.71 10.3 0.2 5.6 4 3 1 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.17 ORY02990.1 - 0.0025 18.2 1.2 1.2 9.5 0.0 4.5 3 2 2 5 5 5 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 ORY02990.1 - 0.0036 17.9 0.1 25 5.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY02990.1 - 0.028 14.5 5.1 14 6.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY02990.1 - 0.033 14.1 0.1 3.1 7.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY02990.1 - 0.038 14.3 0.8 17 5.8 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat APAF1_C PF17908.1 ORY02990.1 - 0.087 12.8 2.2 8.5 6.4 0.0 3.2 3 1 0 3 3 3 0 APAF-1 helical domain TPR_8 PF13181.6 ORY02990.1 - 0.13 12.5 1.1 65 4.1 0.0 4.5 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY02990.1 - 0.8 10.2 2.7 4.7e+02 1.6 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 ORY02991.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain GvpG PF05120.12 ORY02991.1 - 0.02 14.9 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Gas vesicle protein G WD40 PF00400.32 ORY02992.1 - 6.8e-19 67.9 14.5 0.00026 21.7 0.9 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY02992.1 - 2.4e-09 37.3 0.1 0.024 14.9 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY02992.1 - 0.05 12.9 0.2 0.6 9.4 0.0 2.6 3 1 0 3 3 3 0 WD40-like domain Chitin_synth_2 PF03142.15 ORY02993.1 - 2.8e-237 788.5 1.3 4e-237 788.0 1.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY02993.1 - 2.1e-167 558.3 0.4 2.8e-167 557.9 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY02993.1 - 6.1e-19 67.7 0.2 3.2e-18 65.4 0.3 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORY02993.1 - 2.9e-11 43.7 0.0 3.7e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORY02993.1 - 9.7e-11 41.7 3.5 3e-07 30.5 0.1 4.1 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ORY02993.1 - 2.3e-10 40.7 3.3 2.8e-10 40.5 0.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY02993.1 - 0.00083 19.2 0.0 0.43 10.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF726 PF05277.12 ORY02994.1 - 7.1e-113 377.0 2.9 1.8e-112 375.6 2.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF726) SNF2_N PF00176.23 ORY02995.1 - 1.9e-66 224.2 0.1 5.7e-66 222.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY02995.1 - 5.2e-22 78.3 0.2 2e-20 73.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY02995.1 - 4e-15 55.7 0.0 1.7e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORY02995.1 - 1.5e-07 31.5 0.0 4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY02995.1 - 6.8e-06 26.0 0.0 3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 ORY02995.1 - 0.0027 16.9 0.1 0.0049 16.1 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MFS_1 PF07690.16 ORY02996.1 - 1.1e-14 54.2 24.0 1.5e-14 53.7 24.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY02996.1 - 7.8e-09 35.4 6.9 7.8e-09 35.4 6.9 2.1 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 DUF1129 PF06570.11 ORY02996.1 - 1.2 8.6 3.6 1.4 8.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Aminotran_1_2 PF00155.21 ORY02997.1 - 1.6e-47 162.5 0.0 1.7e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY02997.1 - 0.0022 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2778 PF10908.8 ORY02997.1 - 0.17 12.2 0.0 0.42 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) zf-C2HE PF16278.5 ORY02998.1 - 0.02 15.4 0.7 0.02 15.4 0.7 1.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 ORY02998.1 - 0.026 15.0 6.1 0.084 13.4 6.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY02998.1 - 0.088 13.3 0.5 0.088 13.3 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY02998.1 - 0.16 12.0 5.3 0.48 10.5 5.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF629 PF04780.12 ORY02998.1 - 0.4 9.1 1.3 0.55 8.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 ORY02998.1 - 0.9 10.6 9.6 0.34 11.9 4.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ACBP PF00887.19 ORY02999.1 - 6e-29 100.1 0.5 6.6e-29 100.0 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PhoLip_ATPase_C PF16212.5 ORY03000.1 - 2.1e-64 217.7 22.4 4.4e-64 216.6 22.4 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY03000.1 - 1.6e-22 78.9 6.4 1.6e-22 78.9 6.4 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY03000.1 - 1.1e-10 42.1 0.3 0.0051 17.1 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY03000.1 - 2.3e-10 40.4 0.0 7.7e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY03000.1 - 0.00039 20.0 3.1 0.004 16.7 0.0 2.8 2 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY03000.1 - 0.051 13.3 0.1 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase EMP24_GP25L PF01105.24 ORY03001.1 - 2.2e-52 177.6 0.2 2.6e-52 177.4 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 ORY03001.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain Pkinase PF00069.25 ORY03002.1 - 3.7e-65 219.9 0.0 4.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03002.1 - 1.5e-37 129.3 0.0 1.9e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY03002.1 - 2.1e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY03002.1 - 0.00048 19.6 0.3 0.00082 18.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY03002.1 - 0.014 14.3 0.2 0.02 13.9 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 ORY03002.1 - 0.021 14.4 0.0 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY03002.1 - 0.052 12.3 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY03002.1 - 0.14 12.1 1.9 0.27 11.1 1.3 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family G-alpha PF00503.20 ORY03003.1 - 2.7e-114 382.0 0.6 3.1e-114 381.8 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY03003.1 - 4.6e-15 55.5 0.2 1.4e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY03003.1 - 4.7e-05 22.9 0.1 0.27 10.6 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY03003.1 - 0.0016 18.7 0.2 0.54 10.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY03003.1 - 0.036 14.1 0.0 8.7 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY03003.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMP_C2CD2L PF18696.1 ORY03003.1 - 0.11 12.4 0.3 0.9 9.4 0.1 2.2 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain WD40 PF00400.32 ORY03006.1 - 6.5e-23 80.6 9.9 0.001 19.8 0.1 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 ORY03006.1 - 1.7e-10 40.6 11.7 3.4e-10 39.6 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY03006.1 - 4.1e-09 36.2 12.0 9.5e-09 35.0 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 ORY03006.1 - 4.3e-08 33.3 0.6 0.14 12.4 0.0 4.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_3 PF13920.6 ORY03006.1 - 5.4e-08 32.6 8.3 5.4e-08 32.6 8.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY03006.1 - 1e-07 32.1 11.0 3.2e-07 30.6 11.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY03006.1 - 4.5e-06 26.6 7.6 1.5e-05 24.9 7.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY03006.1 - 5.5e-05 23.0 10.9 5.5e-05 23.0 10.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY03006.1 - 0.00037 20.6 11.1 0.00097 19.2 11.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY03006.1 - 0.0038 17.1 9.0 0.01 15.7 9.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY03006.1 - 0.0072 16.4 4.3 0.016 15.3 4.3 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 LCD1 PF09798.9 ORY03006.1 - 0.014 14.0 3.8 0.02 13.5 3.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein zf-RING_4 PF14570.6 ORY03006.1 - 0.024 14.4 7.9 0.82 9.5 9.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain U-box PF04564.15 ORY03006.1 - 0.028 14.6 0.0 0.092 12.9 0.0 1.8 1 0 0 1 1 1 0 U-box domain CAMSAP_CC1 PF17095.5 ORY03006.1 - 0.051 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF2383 PF09537.10 ORY03006.1 - 0.14 12.5 0.3 0.35 11.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) CorA PF01544.18 ORY03006.1 - 0.22 10.8 1.1 0.36 10.1 1.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-rbx1 PF12678.7 ORY03006.1 - 0.27 11.6 15.9 0.073 13.4 10.0 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.12 ORY03006.1 - 0.43 10.6 5.7 0.91 9.6 5.7 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_11 PF17123.5 ORY03006.1 - 0.98 9.2 7.3 2.8 7.8 7.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY03006.1 - 1.6 8.8 5.7 1.4 9.0 2.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.21 ORY03007.1 - 9.4e-20 70.6 42.4 3e-13 49.8 9.0 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 ORY03007.1 - 2.5e-18 66.4 2.2 5.2e-18 65.4 2.2 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 ORY03007.1 - 5.9e-05 22.9 5.3 5.9e-05 22.9 5.3 4.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY03007.1 - 0.00032 21.0 8.2 0.00032 21.0 8.2 4.6 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY03007.1 - 0.00035 20.5 4.8 0.00035 20.5 4.8 3.8 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY03007.1 - 0.00042 20.2 9.9 0.00042 20.2 9.9 4.3 3 2 1 4 4 4 1 zinc-RING finger domain FRP PF18032.1 ORY03007.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Photoprotection regulator fluorescence recovery protein DNA_ligase_ZBD PF03119.16 ORY03007.1 - 4 7.5 12.9 25 5.0 0.2 4.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain ADH_zinc_N PF00107.26 ORY03009.1 - 6.6e-07 29.4 0.1 1e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_deac_1 PF01522.21 ORY03010.1 - 3.2e-33 114.3 0.0 5e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY03010.1 - 4.4e-05 22.8 0.0 5.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 B-block_TFIIIC PF04182.12 ORY03011.1 - 6.9e-16 58.2 0.8 1.7e-13 50.5 0.0 4.2 6 0 0 6 6 6 1 B-block binding subunit of TFIIIC PHD PF00628.29 ORY03011.1 - 1.6e-09 37.5 9.3 2.8e-09 36.7 9.3 1.4 1 0 0 1 1 1 1 PHD-finger Myb_DNA-binding PF00249.31 ORY03011.1 - 0.00024 21.2 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY03011.1 - 0.062 13.6 0.2 0.2 12.0 0.2 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain MarR_2 PF12802.7 ORY03011.1 - 0.067 13.1 0.1 1.7 8.6 0.0 3.2 2 1 0 2 2 2 0 MarR family Homeodomain PF00046.29 ORY03011.1 - 0.085 12.7 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain MutS_V PF00488.21 ORY03012.1 - 1.9e-77 259.6 0.3 4.6e-77 258.3 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 ORY03012.1 - 1.7e-41 142.6 0.4 4.2e-41 141.3 0.1 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ORY03012.1 - 7.6e-35 119.6 0.7 1.5e-34 118.6 0.3 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORY03012.1 - 3.5e-13 50.0 0.0 2e-12 47.5 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY03012.1 - 1.6e-11 44.4 2.6 1.8e-11 44.3 0.4 2.3 2 0 0 2 2 2 1 MutS family domain IV DnaJ_C PF01556.18 ORY03013.1 - 3.2e-34 118.2 0.2 4.3e-34 117.7 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY03013.1 - 2.2e-27 94.9 3.6 5e-27 93.8 3.6 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY03013.1 - 1.4e-15 57.4 15.8 2.2e-15 56.7 15.8 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY03013.1 - 1.5e-06 28.1 4.1 0.003 17.5 0.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Gp-FAR-1 PF05823.12 ORY03013.1 - 0.022 15.1 0.8 0.2 12.0 0.1 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HypA PF01155.19 ORY03013.1 - 0.024 14.7 10.6 0.93 9.5 0.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 ORY03013.1 - 0.5 10.0 5.3 3.1 7.4 0.9 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 FdhE PF04216.12 ORY03013.1 - 1.7 8.4 3.8 2.9 7.7 3.8 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Cytochrome_CBB3 PF13442.6 ORY03013.1 - 1.7 9.0 6.7 22 5.4 0.3 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1272 PF06906.11 ORY03013.1 - 2.2 8.4 6.6 2.3 8.3 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 ORY03013.1 - 4.4 7.4 9.9 8.5 6.5 9.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon BAR PF03114.18 ORY03015.1 - 3.1e-41 141.6 12.4 4.1e-41 141.2 12.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 ORY03015.1 - 3.3e-14 52.5 0.2 6.2e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY03015.1 - 5.2e-14 51.6 0.2 9.2e-14 50.8 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY03015.1 - 3.1e-12 46.0 0.4 5.2e-12 45.3 0.4 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 ORY03015.1 - 0.0004 20.2 8.8 0.0004 20.2 8.8 2.1 1 1 0 2 2 2 1 BAR domain of APPL family DUF1501 PF07394.12 ORY03015.1 - 0.029 13.4 1.7 0.045 12.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ntox28 PF15605.6 ORY03015.1 - 0.36 11.1 2.8 1.3 9.3 2.3 2.2 1 1 1 2 2 2 0 Bacterial toxin 28 FapA PF03961.13 ORY03015.1 - 4.4 5.8 8.5 0.51 8.9 2.8 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 ORY03015.1 - 4.7 7.5 11.8 0.67 10.2 4.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cys_Met_Meta_PP PF01053.20 ORY03016.1 - 1.5e-137 458.2 0.0 1.9e-137 457.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY03016.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY03016.1 - 0.0026 17.1 0.0 0.0084 15.5 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PNRC PF15365.6 ORY03017.1 - 3.2e-07 30.0 2.0 3.2e-07 30.0 2.0 2.8 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif zf-C2H2 PF00096.26 ORY03018.1 - 3e-13 49.4 10.1 3.2e-06 27.3 4.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03018.1 - 1.5e-09 37.9 8.1 0.00021 21.8 2.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY03018.1 - 2e-07 31.1 0.7 2e-07 31.1 0.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY03018.1 - 0.0037 17.5 1.4 0.75 10.2 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY03018.1 - 0.012 15.8 1.9 0.019 15.1 1.9 1.4 1 1 0 1 1 1 0 Aberrant zinc-finger Ogr_Delta PF04606.12 ORY03018.1 - 0.028 14.4 0.5 0.64 10.0 0.1 2.2 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.6 ORY03018.1 - 0.084 12.6 1.5 0.084 12.6 1.5 2.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 ORY03018.1 - 0.48 10.1 2.9 0.24 11.1 0.4 1.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 ORY03018.1 - 8.8 6.4 10.5 5.4 7.1 0.5 2.6 2 2 0 2 2 2 0 C2H2-type zinc finger STE PF02200.16 ORY03019.1 - 1.3e-48 164.0 0.2 1.5e-48 163.7 0.2 1.1 1 0 0 1 1 1 1 STE like transcription factor Metallophos PF00149.28 ORY03020.1 - 7.4e-15 56.0 0.0 1e-14 55.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY03020.1 - 1.1e-06 28.9 0.0 2.3e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M18 PF02127.15 ORY03020.1 - 0.2 10.4 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) Acyl_transf_1 PF00698.21 ORY03021.1 - 2.4e-19 70.0 0.7 3.7e-19 69.4 0.7 1.3 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 ORY03021.1 - 0.00015 21.6 2.0 0.00094 19.0 2.0 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis CM_1 PF07736.11 ORY03021.1 - 0.033 14.6 0.3 1.3 9.4 0.0 2.7 2 1 1 3 3 3 0 Chorismate mutase type I PilO PF04350.13 ORY03021.1 - 0.036 14.2 0.1 0.083 13.0 0.1 1.7 1 0 0 1 1 1 0 Pilus assembly protein, PilO LIDHydrolase PF10230.9 ORY03021.1 - 0.071 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF1216 PF06746.11 ORY03021.1 - 0.28 11.2 4.4 1.5 8.8 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1216) PH PF00169.29 ORY03022.1 - 2.5e-10 40.8 0.1 5.4e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 PH domain RRM_1 PF00076.22 ORY03023.1 - 3.1e-35 119.8 0.1 7.1e-17 61.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY03023.1 - 2.3e-11 43.7 0.1 0.00011 22.3 0.1 2.8 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY03023.1 - 0.0014 18.6 0.1 0.62 10.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY03023.1 - 0.033 14.2 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif COMMD1_N PF17221.3 ORY03023.1 - 0.046 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 COMMD1 N-terminal domain PseudoU_synth_2 PF00849.22 ORY03024.1 - 0.00029 21.0 0.4 0.0004 20.5 0.4 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase MIP PF00230.20 ORY03025.1 - 1.2e-30 106.9 10.8 1.6e-30 106.5 10.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC_membrane PF00664.23 ORY03080.1 - 3.3e-40 138.5 4.8 4.2e-40 138.1 4.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY03080.1 - 1.3e-32 113.1 0.0 2.3e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY03080.1 - 4.9e-07 29.4 0.4 4.1e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY03080.1 - 0.00021 21.1 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 ORY03080.1 - 0.0018 17.6 0.2 0.0056 16.0 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 ORY03080.1 - 0.0067 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY03080.1 - 0.0072 16.7 0.5 0.017 15.5 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY03080.1 - 0.0081 15.9 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY03080.1 - 0.031 14.2 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 ORY03080.1 - 0.031 13.4 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PRK PF00485.18 ORY03080.1 - 0.065 13.0 0.1 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 ORY03080.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NDUF_B12 PF08122.12 ORY03080.1 - 0.086 12.9 1.7 0.58 10.2 0.2 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family AAA_24 PF13479.6 ORY03080.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 ORY03080.1 - 0.12 12.5 0.2 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 ORY03080.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY03080.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_hydro_61 PF03443.14 ORY03081.1 - 0.0015 18.5 0.1 0.11 12.5 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORY03081.1 - 0.0024 18.5 1.4 0.012 16.2 1.4 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GPI-anchored PF10342.9 ORY03081.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family COQ9 PF08511.11 ORY03082.1 - 1.3e-33 114.6 0.2 2.1e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 COQ9 HAD_2 PF13419.6 ORY03083.1 - 1e-25 90.9 0.0 1.3e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY03083.1 - 1.6e-15 57.9 0.0 6.6e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY03083.1 - 0.0003 20.8 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ORY03083.1 - 0.041 14.3 0.1 0.054 13.9 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MBOAT PF03062.19 ORY03084.1 - 2e-31 109.7 27.3 2e-31 109.7 27.3 2.4 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY03084.1 - 0.0058 16.9 4.0 0.0061 16.8 1.0 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HalX PF08663.10 ORY03084.1 - 0.47 10.8 2.5 0.82 10.0 2.5 1.3 1 0 0 1 1 1 0 HalX domain p450 PF00067.22 ORY03085.1 - 6.3e-83 279.0 0.0 7.2e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThrE PF06738.12 ORY03086.1 - 6e-58 196.1 20.6 1.8e-53 181.4 1.8 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY03086.1 - 5e-12 46.1 31.8 1e-09 38.6 10.9 2.5 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Pox_A9 PF04835.12 ORY03086.1 - 0.1 12.7 4.0 7.6 6.8 0.5 2.9 2 0 0 2 2 2 0 A9 protein conserved region ThrE PF06738.12 ORY03087.1 - 8e-55 185.8 22.4 1.6e-51 175.0 2.6 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY03087.1 - 1.2e-11 44.9 32.2 1e-10 41.8 11.5 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE SPRY PF00622.28 ORY03088.1 - 9e-17 61.3 0.1 1.7e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 ORY03088.1 - 1.2e-10 41.1 5.8 2.2e-10 40.3 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY03088.1 - 0.00039 20.2 6.4 0.00083 19.2 6.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY03088.1 - 0.0015 18.8 6.7 0.0041 17.4 6.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY03088.1 - 0.3 11.1 6.3 0.64 10.0 6.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 ORY03088.1 - 0.5 10.1 7.8 2.3 8.0 4.1 2.6 2 0 0 2 2 2 0 P-11 zinc finger BCDHK_Adom3 PF10436.9 ORY03089.1 - 1.4e-65 220.0 0.0 3.9e-65 218.6 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY03089.1 - 3e-14 53.5 0.0 8.6e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY03089.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 ORY03089.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family zf-C2H2_2 PF12756.7 ORY03090.1 - 1.6e-37 127.9 12.6 2.5e-22 79.1 1.1 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORY03090.1 - 7.2e-08 32.5 17.6 0.0018 18.6 0.9 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03090.1 - 4e-07 30.3 16.2 0.015 16.1 0.3 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 ORY03090.1 - 5.2e-06 26.7 0.3 0.0016 18.7 0.5 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY03090.1 - 4.1e-05 23.7 3.3 0.0001 22.5 0.7 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY03090.1 - 0.0037 17.0 0.1 0.0037 17.0 0.1 3.7 4 0 0 4 4 4 1 zinc-finger C2H2-type CpXC PF14353.6 ORY03090.1 - 0.0039 17.2 0.2 0.32 11.1 0.0 2.8 2 0 0 2 2 2 1 CpXC protein zf-BED PF02892.15 ORY03090.1 - 0.0058 16.6 0.1 0.0058 16.6 0.1 4.4 4 0 0 4 4 4 1 BED zinc finger zf-C2H2_6 PF13912.6 ORY03090.1 - 0.022 14.8 10.4 0.063 13.3 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Menin PF05053.13 ORY03090.1 - 8.4 4.6 10.4 12 4.1 10.4 1.1 1 0 0 1 1 1 0 Menin DPPIV_N PF00930.21 ORY03091.1 - 1.6e-60 204.8 0.0 4.6e-60 203.2 0.1 1.8 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY03091.1 - 2.2e-55 187.4 0.0 6.1e-55 186.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY03091.1 - 3.9e-07 30.0 0.0 1.6e-06 27.9 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORY03091.1 - 5.8e-06 26.1 0.0 4.6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 ORY03091.1 - 2.2e-05 24.1 0.0 6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY03091.1 - 7.9e-05 23.4 0.0 0.00018 22.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORY03091.1 - 0.00061 19.7 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY03091.1 - 0.00097 18.5 0.5 0.0053 16.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORY03091.1 - 0.0018 18.2 0.0 0.51 10.2 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 ORY03091.1 - 0.0053 16.6 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ORY03091.1 - 0.0068 16.1 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 ORY03091.1 - 0.059 12.2 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Tannase PF07519.11 ORY03091.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase PAS_9 PF13426.7 ORY03092.1 - 7.1e-29 100.1 0.0 3.5e-15 56.1 0.0 4.1 5 0 0 5 5 5 3 PAS domain PAS_3 PF08447.12 ORY03092.1 - 1.8e-23 82.6 0.0 8.6e-14 51.6 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 ORY03092.1 - 1.5e-21 76.5 0.0 2.8e-07 30.5 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORY03092.1 - 1.2e-14 54.4 0.0 3e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORY03092.1 - 3.4e-12 46.6 0.0 0.00073 19.8 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_2 PF08446.11 ORY03092.1 - 1.9e-06 28.5 0.0 0.29 11.8 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 ORY03092.1 - 0.0063 16.5 0.0 3.2 7.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain GATA PF00320.27 ORY03092.1 - 0.023 14.3 5.5 0.056 13.1 5.5 1.7 1 0 0 1 1 1 0 GATA zinc finger TMCCDC2 PF15844.5 ORY03092.1 - 0.064 13.2 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Synaptobrevin PF00957.21 ORY03093.1 - 4.6e-32 109.7 4.3 5.1e-32 109.5 4.3 1.0 1 0 0 1 1 1 1 Synaptobrevin RIFIN PF02009.16 ORY03093.1 - 0.0023 17.9 0.5 0.0024 17.8 0.5 1.0 1 0 0 1 1 1 1 Rifin MCU PF04678.13 ORY03093.1 - 0.15 12.2 0.5 0.16 12.0 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter T4bSS_IcmS PF12608.8 ORY03093.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.3 1 1 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment DUF2937 PF11157.8 ORY03093.1 - 0.33 10.6 2.8 0.18 11.5 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) SNARE PF05739.19 ORY03093.1 - 3.2 7.8 12.6 1.5 8.9 8.5 2.5 2 1 0 2 2 2 0 SNARE domain Kinesin PF00225.23 ORY03094.1 - 6e-102 341.0 0.0 7.4e-102 340.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY03094.1 - 2.2e-20 73.1 0.0 4.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF2370 PF10176.9 ORY03095.1 - 4.9e-61 206.3 8.8 2.1e-52 178.0 0.1 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF2370) DUF202 PF02656.15 ORY03095.1 - 0.09 13.2 0.3 0.36 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) IF3_N PF05198.16 ORY03096.1 - 8.1e-17 61.3 0.2 1.4e-16 60.5 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 ORY03096.1 - 1.2e-11 44.4 0.2 2.1e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 ORY03096.1 - 0.0041 16.8 4.5 0.0063 16.2 3.9 1.6 1 1 1 2 2 2 1 Mitochondrial translation initiation factor KxDL PF10241.9 ORY03097.1 - 0.012 15.9 3.8 0.019 15.2 3.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein SWIRM-assoc_1 PF16495.5 ORY03097.1 - 0.014 15.3 12.2 0.022 14.7 12.2 1.3 1 0 0 1 1 1 0 SWIRM-associated region 1 NAM-associated PF14303.6 ORY03097.1 - 3.3 8.4 18.2 1.7 9.3 16.5 1.4 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain EMC3_TMCO1 PF01956.16 ORY03097.1 - 9.3 6.0 7.5 13 5.5 7.5 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PDCD2_C PF04194.13 ORY03098.1 - 1e-39 136.4 0.1 1e-39 136.4 0.1 3.0 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain PhnA_Zn_Ribbon PF08274.12 ORY03098.1 - 0.035 14.1 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon YdjO PF14169.6 ORY03098.1 - 4.4 7.1 12.0 0.19 11.5 0.3 3.6 4 0 0 4 4 4 0 Cold-inducible protein YdjO TPR_1 PF00515.28 ORY03099.1 - 1.9e-32 109.7 8.1 1e-06 28.3 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03099.1 - 1.4e-31 106.0 7.7 0.00047 20.1 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY03099.1 - 6.4e-21 72.8 8.8 0.0012 18.9 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03099.1 - 6.4e-19 68.2 0.5 8.9e-05 22.9 0.0 5.8 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY03099.1 - 1.1e-16 61.1 0.0 1.5e-06 28.7 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY03099.1 - 1.7e-16 60.2 3.8 0.037 14.3 0.5 6.0 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03099.1 - 5.4e-16 58.0 0.7 0.00081 19.0 0.0 6.0 5 1 2 7 7 7 4 TPR repeat TPR_14 PF13428.6 ORY03099.1 - 6e-15 54.7 0.6 0.035 14.9 0.0 7.1 3 1 5 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY03099.1 - 2.5e-13 49.0 5.7 0.054 13.5 0.0 7.5 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY03099.1 - 1.5e-11 43.9 0.8 0.0066 16.8 0.0 6.8 6 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY03099.1 - 5.4e-11 42.6 8.2 0.0044 17.2 0.2 4.1 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY03099.1 - 1.2e-09 38.2 6.3 0.0061 17.1 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORY03099.1 - 3e-06 27.1 0.9 0.00029 20.6 0.4 3.6 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 ORY03099.1 - 2.7e-05 24.2 0.0 0.73 10.0 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat ChAPs PF09295.10 ORY03099.1 - 5.9e-05 22.2 0.0 0.063 12.3 0.0 2.6 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Foie-gras_1 PF11817.8 ORY03099.1 - 0.0021 17.7 1.1 4.1 6.9 0.1 3.2 3 0 0 3 3 3 1 Foie gras liver health family 1 Coatomer_E PF04733.14 ORY03099.1 - 0.0036 16.8 0.1 2.3 7.6 0.0 3.0 2 1 0 3 3 3 1 Coatomer epsilon subunit EST1_DNA_bind PF10373.9 ORY03099.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain SRP_TPR_like PF17004.5 ORY03099.1 - 0.03 14.4 1.5 3.3 7.8 0.3 2.6 2 0 0 2 2 2 0 Putative TPR-like repeat NARP1 PF12569.8 ORY03099.1 - 0.25 10.2 6.9 1.3 7.8 0.8 3.0 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 ORY03099.1 - 1.5 8.8 7.8 2.3 8.2 0.1 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 ORY03100.1 - 1.6e-55 184.8 0.0 8.8e-18 63.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY03100.1 - 0.00016 21.7 0.0 0.22 11.6 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 ORY03100.1 - 0.0016 18.4 0.0 2.6 8.2 0.0 3.2 3 0 0 3 3 3 2 Limkain b1 RRM_Rrp7 PF17799.1 ORY03100.1 - 0.0099 15.7 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain FNIP_M PF14637.6 ORY03100.1 - 0.018 15.1 0.0 7.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Folliculin-interacting protein middle domain Lipoprotein_18 PF06804.11 ORY03100.1 - 0.064 12.3 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 NlpB/DapX lipoprotein DUF3932 PF13068.6 ORY03100.1 - 0.22 11.8 0.0 4.7 7.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) RRM_1 PF00076.22 ORY03101.1 - 8e-16 57.6 0.1 1.3e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY03101.1 - 7e-05 22.8 0.7 9.4e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 ORY03101.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY03101.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3611 PF12263.8 ORY03102.1 - 0.22 11.4 4.6 0.051 13.5 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) SK_channel PF03530.14 ORY03102.1 - 0.66 10.0 3.2 0.65 10.0 0.3 2.2 2 0 0 2 2 2 0 Calcium-activated SK potassium channel HAUS5 PF14817.6 ORY03103.1 - 7.9e-12 44.8 18.8 5.9e-11 41.9 7.8 2.6 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 5 SAM_Exu PF18609.1 ORY03103.1 - 0.039 14.0 0.2 0.68 10.1 0.0 2.8 2 0 0 2 2 2 0 Exuperantia SAM-like domain SRP14 PF02290.15 ORY03103.1 - 0.28 11.6 2.6 28 5.2 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle 14kD protein DUF1043 PF06295.12 ORY03103.1 - 1.5 8.8 14.2 0.45 10.5 1.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 ORY03103.1 - 1.8 8.6 10.4 0.1 12.7 0.9 3.5 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.13 ORY03103.1 - 3.4 7.8 19.2 3.5 7.8 4.2 4.6 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 JHD PF17811.1 ORY03104.1 - 2.2e-13 50.6 0.0 4.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 ORY03104.1 - 1.2e-09 38.6 0.5 1.1e-08 35.4 0.5 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 ORY03104.1 - 1.5e-07 31.4 0.2 6.9e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.29 ORY03104.1 - 1.1e-05 25.2 10.9 2.2e-05 24.3 10.9 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 ORY03104.1 - 0.021 14.7 3.2 0.045 13.7 3.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YscO PF07321.12 ORY03104.1 - 1.4 8.9 3.0 0.55 10.2 0.4 1.6 2 0 0 2 2 2 0 Type III secretion protein YscO zf-RING_9 PF13901.6 ORY03104.1 - 2.7 7.9 9.5 1.1 9.2 6.5 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TLD PF07534.16 ORY03105.1 - 9.6e-40 136.0 0.0 1.1e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 TLD GerA PF03323.13 ORY03106.1 - 0.087 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein TLD PF07534.16 ORY03107.1 - 3.9e-34 117.8 0.0 5.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 TLD Isochorismatase PF00857.20 ORY03107.1 - 0.13 12.5 0.0 9 6.4 0.0 2.2 2 0 0 2 2 2 0 Isochorismatase family UPRTase PF14681.6 ORY03108.1 - 8e-82 273.7 0.0 9.8e-82 273.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY03108.1 - 8e-05 22.2 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 ORY03108.1 - 0.16 11.9 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DUF202 PF02656.15 ORY03109.1 - 5e-05 23.6 2.5 0.00011 22.6 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HSP90 PF00183.18 ORY03110.1 - 2.6e-237 788.8 32.6 3.2e-237 788.5 32.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY03110.1 - 3.8e-14 53.2 0.0 7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY03110.1 - 2.3e-09 37.2 0.1 2.3e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 ORY03110.1 - 0.046 13.7 0.7 0.21 11.6 0.7 2.1 1 1 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF1198 PF06711.11 ORY03110.1 - 0.18 11.9 0.4 1.1 9.3 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1198) DUF1943 PF09172.11 ORY03110.1 - 8 5.6 9.3 0.36 10.0 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) PQQ_2 PF13360.6 ORY03111.1 - 1.3e-09 38.0 0.0 0.00028 20.6 0.0 2.4 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 ORY03111.1 - 2.4e-07 30.3 0.2 0.084 12.8 0.0 4.3 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 ORY03111.1 - 0.013 15.9 0.9 0.91 10.1 0.0 3.7 4 1 0 4 4 4 0 PQQ-like domain CBM_5_12 PF02839.14 ORY03112.1 - 1.9e-05 24.9 11.9 1.9e-05 24.9 11.9 1.9 2 1 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORY03112.1 - 0.034 14.1 6.0 0.037 14.0 5.7 1.3 1 1 0 1 1 1 0 Cellulose-binding domain Glyco_hydro_18 PF00704.28 ORY03113.1 - 2.3e-58 198.4 0.6 2.7e-58 198.1 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 ORY03114.1 - 1.5e-68 231.9 2.2 1.8e-68 231.6 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Yip1 PF04893.17 ORY03115.1 - 1.9e-21 76.6 9.3 3.1e-21 75.9 9.3 1.3 1 1 0 1 1 1 1 Yip1 domain DDE_1 PF03184.19 ORY03116.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease RRM_1 PF00076.22 ORY03117.1 - 1.5e-36 124.0 0.0 7.1e-17 61.0 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY03117.1 - 2.5e-16 59.6 0.7 1.4e-05 25.2 0.0 3.3 3 0 0 3 3 3 3 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 ORY03117.1 - 0.001 19.1 0.0 4 7.6 0.0 3.5 3 0 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 ORY03117.1 - 0.16 11.9 0.0 2.7 7.9 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif FNIP_C PF14638.6 ORY03118.1 - 3.2e-43 147.6 0.0 4.3e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus SQS_PSY PF00494.19 ORY03118.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase FNIP_M PF14637.6 ORY03119.1 - 2e-59 201.4 0.1 2.7e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_N PF14636.6 ORY03119.1 - 5e-05 24.3 0.1 5e-05 24.3 0.1 2.5 3 0 0 3 3 3 1 Folliculin-interacting protein N-terminus EntA_Immun PF08951.10 ORY03119.1 - 0.064 13.6 0.1 0.45 10.9 0.1 2.4 2 0 0 2 2 2 0 Enterocin A Immunity DUF3712 PF12505.8 ORY03120.1 - 1.7e-20 73.5 0.8 2.3e-12 47.3 0.2 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY03120.1 - 0.00042 20.8 0.0 0.83 10.2 0.0 4.0 4 0 0 4 4 4 1 Late embryogenesis abundant protein SMK-1 PF04802.15 ORY03121.1 - 3.2e-83 278.3 7.5 6.7e-83 277.2 7.5 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 ORY03121.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 ORY03121.1 - 0.0066 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain DUF1647 PF07801.11 ORY03121.1 - 0.041 13.6 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Importin_rep_3 PF18806.1 ORY03121.1 - 0.17 11.9 0.1 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Importin 13 repeat ALS_ss_C PF10369.9 ORY03122.1 - 7.7e-19 67.7 0.1 1.6e-16 60.3 0.0 2.6 3 0 0 3 3 3 2 Small subunit of acetolactate synthase ACT PF01842.25 ORY03122.1 - 2.5e-15 56.0 0.1 4.4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORY03122.1 - 1.5e-09 37.6 0.0 3.4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 ACT domain P_C10 PF14974.6 ORY03122.1 - 0.13 12.4 0.2 0.32 11.1 0.2 1.7 1 1 0 1 1 1 0 Protein C10 ACT_4 PF13291.6 ORY03122.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain Glyco_transf_28 PF03033.20 ORY03123.1 - 1.1e-21 77.4 0.0 2.1e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain VPS13_C PF16909.5 ORY03123.1 - 9.9e-05 22.2 0.2 9.9e-05 22.2 0.2 2.8 3 1 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal UDPGT PF00201.18 ORY03123.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Pkinase PF00069.25 ORY03171.1 - 8.6e-66 222.0 0.0 1.6e-65 221.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03171.1 - 2.9e-35 121.8 0.0 4.7e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY03171.1 - 2.8e-10 40.0 0.0 4.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY03171.1 - 0.00013 20.9 0.0 0.00024 20.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY03171.1 - 0.00017 21.0 0.2 0.00032 20.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY03171.1 - 0.0027 17.7 0.3 0.0042 17.0 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY03171.1 - 0.016 14.1 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF202 PF02656.15 ORY03172.1 - 2e-13 50.5 4.7 2.2e-13 50.5 2.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PrgI PF12666.7 ORY03172.1 - 0.022 15.5 0.4 0.022 15.5 0.4 1.8 2 0 0 2 2 2 0 PrgI family protein Adeno_E3_CR2 PF02439.15 ORY03172.1 - 0.32 10.8 5.3 0.12 12.1 1.6 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 ORY03172.1 - 4.5 5.9 7.8 9.4 4.9 7.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane PF01061.24 ORY03173.1 - 2.7e-39 134.8 20.7 2.7e-39 134.8 20.7 1.7 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY03173.1 - 9.4e-28 97.4 0.0 1.7e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY03173.1 - 1.5e-05 24.9 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ORY03173.1 - 0.0047 17.1 0.0 0.0085 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY03173.1 - 0.0056 16.3 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY03173.1 - 0.0076 16.0 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY03173.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 ORY03173.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 ORY03173.1 - 0.029 13.5 30.4 0.028 13.5 26.9 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_18 PF13238.6 ORY03173.1 - 0.039 14.5 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY03173.1 - 0.065 13.5 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY03173.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 ORY03173.1 - 0.2 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain EamA PF00892.20 ORY03173.1 - 2.5 8.3 15.3 0.18 12.0 6.5 2.9 3 0 0 3 3 3 0 EamA-like transporter family ABC2_membrane_2 PF12679.7 ORY03173.1 - 7 5.8 22.0 37 3.5 18.3 2.9 3 1 0 3 3 3 0 ABC-2 family transporter protein LRR_4 PF12799.7 ORY03174.1 - 0.00016 21.9 19.1 0.021 15.3 0.3 7.6 4 2 3 8 8 8 3 Leucine Rich repeats (2 copies) CAP18_C PF12153.8 ORY03174.1 - 0.11 12.3 1.1 0.27 11.1 1.1 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) LRR_6 PF13516.6 ORY03174.1 - 6.1 7.2 15.6 7.6 6.9 0.0 6.4 8 0 0 8 8 8 0 Leucine Rich repeat L51_S25_CI-B8 PF05047.16 ORY03175.1 - 1.4e-11 44.2 0.2 2.7e-11 43.2 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA PF00004.29 ORY03176.1 - 3.1e-43 147.4 0.0 7.3e-43 146.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY03176.1 - 1.1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY03176.1 - 2.8e-09 36.7 0.3 5.1e-09 35.8 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY03176.1 - 7.8e-07 29.4 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY03176.1 - 7.8e-07 29.4 0.1 0.0042 17.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY03176.1 - 2.1e-05 24.5 0.1 0.0001 22.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ORY03176.1 - 3.5e-05 23.1 0.0 6.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY03176.1 - 9.2e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY03176.1 - 0.00037 20.9 0.1 0.0022 18.4 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 ORY03176.1 - 0.0019 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 ORY03176.1 - 0.003 17.8 0.1 0.0092 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY03176.1 - 0.0041 17.3 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY03176.1 - 0.0043 16.4 0.2 0.24 10.7 0.0 2.8 2 1 0 3 3 3 1 KaiC RNA_helicase PF00910.22 ORY03176.1 - 0.011 16.1 0.0 0.037 14.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.13 ORY03176.1 - 0.012 14.9 0.1 0.026 13.7 0.0 1.6 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_25 PF13481.6 ORY03176.1 - 0.014 15.0 0.4 0.41 10.2 0.2 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY03176.1 - 0.014 15.9 0.0 0.035 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY03176.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 ORY03176.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORY03176.1 - 0.018 14.8 0.4 0.087 12.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY03176.1 - 0.039 13.4 0.1 0.097 12.1 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 ORY03176.1 - 0.044 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY03176.1 - 0.066 13.1 0.1 0.58 10.1 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 ORY03176.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 ORY03176.1 - 0.074 12.8 0.2 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 ORY03176.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 ORY03176.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 ORY03176.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 ORY03176.1 - 0.12 11.5 0.0 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 ORY03176.1 - 0.14 12.7 0.1 0.35 11.4 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.26 ORY03176.1 - 0.16 11.7 0.0 0.57 9.9 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain ANAPC_CDC26 PF10471.9 ORY03177.1 - 0.00021 22.1 2.6 0.00047 20.9 2.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 FadA PF09403.10 ORY03177.1 - 0.0021 18.5 0.7 0.0025 18.2 0.7 1.1 1 0 0 1 1 1 1 Adhesion protein FadA CRF PF00473.17 ORY03177.1 - 0.059 13.4 0.6 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Corticotropin-releasing factor family Herpes_UL36 PF03586.13 ORY03177.1 - 0.066 12.5 0.0 0.079 12.3 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Ribosomal_L38e PF01781.18 ORY03178.1 - 1.1e-35 121.6 2.0 1.2e-35 121.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 ORY03178.1 - 0.039 14.2 0.0 0.046 14.0 0.0 1.0 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain UPF0086 PF01868.16 ORY03178.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Pkinase PF00069.25 ORY03179.1 - 1.1e-72 244.6 0.0 1.3e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03179.1 - 2.3e-35 122.1 0.0 3e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY03179.1 - 2.4e-06 27.1 0.0 4.1e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY03179.1 - 0.052 12.5 0.2 0.075 12.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Trypsin PF00089.26 ORY03180.1 - 1.1e-13 51.5 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 ORY03180.1 - 0.0015 18.9 0.1 0.0026 18.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ras PF00071.22 ORY03181.1 - 7.1e-56 188.3 0.0 8.2e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY03181.1 - 1.3e-21 77.0 0.0 2.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY03181.1 - 3.3e-06 26.7 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY03181.1 - 0.0023 17.4 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit BPL_LplA_LipB PF03099.19 ORY03182.1 - 2.7e-05 24.1 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 ORY03182.1 - 0.02 14.9 0.0 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus adh_short PF00106.25 ORY03183.1 - 3.7e-78 261.5 12.3 1.9e-42 145.0 1.8 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY03183.1 - 8.8e-65 218.5 6.2 5e-37 127.7 0.4 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY03183.1 - 5.3e-32 111.2 7.0 2e-18 67.0 1.4 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 ORY03183.1 - 5.7e-31 106.6 0.0 1.1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY03183.1 - 1.5e-07 31.6 0.0 2.1e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NmrA PF05368.13 ORY03183.1 - 0.035 13.7 1.6 4 6.9 0.1 2.5 2 0 0 2 2 2 0 NmrA-like family PglL_A PF15864.5 ORY03183.1 - 3.8 7.3 8.1 10 6.0 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Endosulfine PF04667.17 ORY03184.1 - 1.2e-27 95.8 0.6 1.7e-27 95.3 0.4 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Kelch_4 PF13418.6 ORY03185.1 - 1.2e-26 92.4 7.3 2.1e-10 40.4 0.1 5.3 3 1 2 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY03185.1 - 3.8e-26 90.6 6.8 8.2e-09 35.3 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 ORY03185.1 - 5.6e-25 86.7 3.0 7.1e-10 38.3 0.1 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 ORY03185.1 - 1.1e-24 85.8 1.4 9.3e-08 32.1 0.1 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ORY03185.1 - 3.1e-18 65.6 4.5 2.5e-06 27.6 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY03185.1 - 3.1e-12 45.9 2.7 2.9e-05 23.9 0.1 5.2 6 0 0 6 6 6 3 Kelch motif HBS1_N PF08938.10 ORY03185.1 - 0.037 14.3 1.2 0.24 11.7 0.6 2.8 2 0 0 2 2 2 0 HBS1 N-terminus GP63 PF17471.2 ORY03185.1 - 0.094 12.9 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Gene product 63 FYVE PF01363.21 ORY03188.1 - 1.7e-16 60.1 10.5 1.7e-16 60.1 10.5 2.2 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 ORY03188.1 - 6.2e-08 33.1 0.0 2e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 PH domain Vta1 PF04652.16 ORY03189.1 - 2.6e-52 176.7 2.8 3.7e-52 176.2 2.8 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 ORY03189.1 - 3.6e-16 58.6 0.1 6.8e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Raptor_N PF14538.6 ORY03190.1 - 1.6e-68 229.3 0.0 3e-68 228.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 ORY03190.1 - 7.1e-12 45.7 11.1 0.076 13.9 0.0 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat HEAT PF02985.22 ORY03190.1 - 4e-10 39.1 1.5 0.0004 20.4 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 ORY03190.1 - 2.9e-07 30.8 0.9 7.8e-06 26.2 0.0 3.4 4 1 1 5 5 5 1 HEAT repeats ANAPC4_WD40 PF12894.7 ORY03190.1 - 2.3e-05 24.6 0.3 23 5.3 0.0 5.3 1 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 ORY03190.1 - 0.0007 20.0 0.9 0.091 13.3 0.0 3.2 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 ORY03190.1 - 0.0025 17.9 0.1 0.0097 16.0 0.1 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Cullin PF00888.22 ORY03191.1 - 2.1e-27 96.0 1.0 3.7e-27 95.2 1.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 ORY03191.1 - 2.5e-22 79.2 1.1 7.3e-22 77.6 1.1 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.10 ORY03191.1 - 0.16 12.1 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator Myb_DNA-bind_7 PF15963.5 ORY03192.1 - 1.8e-23 82.3 0.1 3.2e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORY03192.1 - 1e-08 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY03192.1 - 0.0059 16.8 0.5 0.046 14.0 0.1 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain LRR_4 PF12799.7 ORY03193.1 - 0.0006 20.2 6.6 0.65 10.5 0.6 3.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY03193.1 - 0.0021 18.4 3.7 2.7 8.9 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 ORY03193.1 - 0.083 12.7 6.6 4 7.3 2.0 4.0 2 2 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 ORY03193.1 - 1.4 9.2 4.1 10 6.5 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat EB1 PF03271.17 ORY03194.1 - 1.4e-10 41.2 0.6 3e-10 40.2 0.6 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORY03194.1 - 0.0051 17.0 0.4 0.0098 16.1 0.4 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain AbiJ_NTD4 PF18863.1 ORY03194.1 - 0.023 15.2 1.1 0.066 13.7 0.0 2.0 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 IPP-2 PF04979.14 ORY03194.1 - 0.067 13.9 2.7 0.12 13.1 2.4 1.6 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) AMP-binding PF00501.28 ORY03195.1 - 6.1e-107 357.8 0.0 8.5e-107 357.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TPR_1 PF00515.28 ORY03196.1 - 2.2e-57 188.6 27.8 3.3e-08 33.0 0.0 10.3 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03196.1 - 1.6e-50 165.2 23.1 1.2e-07 31.3 0.0 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY03196.1 - 1.4e-38 127.9 20.0 4.2e-07 29.7 0.0 10.2 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 ORY03196.1 - 7.8e-30 101.1 20.4 0.00079 19.6 0.1 10.2 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORY03196.1 - 9.3e-29 97.7 12.6 3.5e-05 24.3 0.0 9.0 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 ORY03196.1 - 2.9e-27 95.0 3.3 5.3e-06 27.0 0.0 6.4 4 1 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03196.1 - 6e-26 90.7 12.5 5.1e-05 23.7 0.8 6.3 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 ORY03196.1 - 5e-25 85.6 13.2 0.013 15.4 0.1 9.4 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY03196.1 - 6.6e-23 80.8 21.6 8.3e-05 22.8 2.4 7.3 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORY03196.1 - 7.8e-23 79.5 23.2 0.00025 21.5 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03196.1 - 8.2e-22 76.6 28.3 5.4e-06 26.0 0.9 8.7 6 3 3 9 9 9 5 TPR repeat TPR_9 PF13371.6 ORY03196.1 - 4.6e-17 61.9 8.0 0.0027 17.8 0.1 5.9 2 2 4 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY03196.1 - 2.9e-12 46.6 14.0 8.3e-09 35.6 2.4 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY03196.1 - 3.9e-10 39.4 13.3 0.0053 16.0 0.4 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.6 ORY03196.1 - 2.6e-06 27.1 12.5 0.49 9.8 0.1 4.9 3 1 0 4 4 4 4 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 ORY03196.1 - 4.2e-05 23.4 9.9 0.29 10.8 0.1 4.7 4 3 0 4 4 4 2 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 ORY03196.1 - 0.0019 18.0 4.9 1.6 8.4 0.2 3.7 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Tcf25 PF04910.14 ORY03196.1 - 0.004 16.3 0.2 0.18 10.8 0.0 2.8 3 1 0 3 3 3 1 Transcriptional repressor TCF25 TPR_MalT PF17874.1 ORY03196.1 - 0.0062 16.0 3.4 0.62 9.4 0.1 3.5 2 1 1 3 3 3 2 MalT-like TPR region TPR_3 PF07720.12 ORY03196.1 - 0.012 15.5 28.8 1.3 9.1 0.9 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY03196.1 - 0.013 15.6 8.3 16 5.6 0.0 5.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 ORY03196.1 - 0.022 15.1 4.6 4.7 7.6 0.0 4.6 4 2 2 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.10 ORY03196.1 - 0.04 12.9 0.0 6.4 5.7 0.0 2.5 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 ORY03196.1 - 0.047 14.1 7.3 9.9 6.6 0.2 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TOM20_plant PF06552.12 ORY03196.1 - 0.072 12.8 2.2 18 5.0 0.1 3.9 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TED PF08341.11 ORY03196.1 - 0.12 12.7 2.0 0.24 11.8 0.0 2.4 2 1 0 2 2 2 0 Thioester domain Clathrin PF00637.20 ORY03196.1 - 0.17 11.7 1.3 6.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_10 PF13374.6 ORY03196.1 - 0.25 11.3 23.4 1.1 9.2 0.4 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 ORY03196.1 - 2.5 8.2 23.9 51 4.0 0.1 6.6 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain DUF410 PF04190.13 ORY03196.1 - 2.9 7.6 8.0 3.2 7.5 0.6 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF410) RPN7 PF10602.9 ORY03196.1 - 6.4 6.5 8.8 14 5.3 0.0 4.3 4 2 1 5 5 4 0 26S proteasome subunit RPN7 SCAI PF12070.8 ORY03197.1 - 1.1e-189 631.8 2.0 1.4e-189 631.4 2.0 1.1 1 0 0 1 1 1 1 Protein SCAI PAE PF03283.13 ORY03197.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase PX PF00787.24 ORY03198.1 - 2.9e-19 69.1 0.0 7.4e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Baculo_PEP_C PF04513.12 ORY03198.1 - 0.014 15.4 2.8 0.029 14.4 2.8 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF632 PF04782.12 ORY03198.1 - 0.035 13.4 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Poty_PP PF08440.10 ORY03198.1 - 0.04 13.0 0.8 0.079 12.0 0.8 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein Syntaxin-6_N PF09177.11 ORY03198.1 - 0.059 13.9 0.2 0.14 12.7 0.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Microvir_H PF04687.12 ORY03198.1 - 0.068 12.5 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) PCRF PF03462.18 ORY03198.1 - 0.83 9.5 3.7 0.83 9.5 2.1 1.7 1 1 0 1 1 1 0 PCRF domain HABP4_PAI-RBP1 PF04774.15 ORY03199.1 - 0.0025 18.6 0.5 0.0038 18.1 0.5 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Abhydrolase_1 PF00561.20 ORY03200.1 - 1e-07 31.9 0.1 1.2e-05 25.1 0.0 2.5 1 1 2 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ORY03200.1 - 0.016 15.0 0.1 0.052 13.3 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 ORY03200.1 - 0.021 14.3 0.2 0.061 12.8 0.2 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Ndr PF03096.14 ORY03200.1 - 0.023 13.4 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.8 ORY03200.1 - 0.064 12.5 0.0 2.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ORY03200.1 - 0.095 12.5 0.0 0.49 10.2 0.0 2.0 2 1 1 3 3 3 0 Serine hydrolase TauD PF02668.16 ORY03201.1 - 2.8e-61 207.7 0.4 3.9e-61 207.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SKN1 PF03935.15 ORY03203.1 - 4.9e-169 562.9 8.3 1e-167 558.6 8.3 1.9 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Shisa PF13908.6 ORY03203.1 - 0.043 14.1 2.4 0.083 13.1 2.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Apt1 PF10351.9 ORY03203.1 - 0.39 9.5 3.3 0.53 9.1 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 ORY03203.1 - 0.41 8.7 6.4 0.6 8.1 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM199X PF15814.5 ORY03203.1 - 3 6.8 10.4 1 8.4 7.4 1.7 2 0 0 2 2 2 0 Protein family FAM199X PI3K_1B_p101 PF10486.9 ORY03203.1 - 4 5.1 7.6 5.6 4.6 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 ORY03203.1 - 8.8 5.9 17.9 14 5.2 17.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ZT_dimer PF16916.5 ORY03256.1 - 5.4e-05 23.2 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SecIII_SopE_N PF05364.14 ORY03257.1 - 0.046 13.8 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus RRM_1 PF00076.22 ORY03258.1 - 1.3e-05 24.9 0.0 0.0013 18.5 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VirC1 PF07015.11 ORY03258.1 - 0.054 12.8 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 VirC1 protein GST_N_3 PF13417.6 ORY03260.1 - 9.2e-17 61.2 0.1 1.7e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY03260.1 - 2.4e-14 53.4 0.0 3.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY03260.1 - 1.5e-11 44.4 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY03260.1 - 9.8e-05 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY03260.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY03260.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ORY03260.1 - 0.044 14.0 0.0 0.24 11.6 0.0 2.2 1 1 1 2 2 2 0 Glutaredoxin RGS PF00615.19 ORY03261.1 - 8.4e-18 64.8 4.0 2.5e-17 63.2 0.2 3.0 3 0 0 3 3 3 1 Regulator of G protein signaling domain RGS-like PF09128.11 ORY03261.1 - 0.02 14.6 0.2 0.18 11.5 0.0 2.5 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain Phage_int_SAM_1 PF02899.17 ORY03261.1 - 0.063 13.6 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CdiI_2 PF18593.1 ORY03261.1 - 0.072 13.8 0.4 0.45 11.2 0.1 2.6 2 0 0 2 2 2 0 CdiI immunity protein CRAL_TRIO PF00650.20 ORY03262.1 - 5.9e-26 91.1 0.0 9.1e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY03262.1 - 5.4e-10 39.6 0.0 8.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ald_Xan_dh_C2 PF02738.18 ORY03263.1 - 2.3e-203 676.6 0.2 3.3e-203 676.1 0.2 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORY03263.1 - 4.5e-52 176.2 0.0 9.4e-52 175.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 ORY03263.1 - 3.1e-35 120.9 0.9 1e-34 119.2 0.9 2.0 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ORY03263.1 - 6e-32 109.5 0.0 1.3e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 ORY03263.1 - 1.2e-26 92.9 0.0 5.6e-25 87.5 0.0 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 ORY03263.1 - 9e-11 41.6 0.2 9e-11 41.6 0.2 2.7 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Rep_fac-A_C PF08646.10 ORY03264.1 - 0.00017 21.3 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain DUF4503 PF14951.6 ORY03264.1 - 0.051 12.0 0.0 0.086 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DOCK_N PF16172.5 ORY03265.1 - 4.6e-91 305.6 0.0 8.5e-91 304.7 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 ORY03265.1 - 2.9e-88 296.8 6.1 7.2e-88 295.5 6.1 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 ORY03265.1 - 7.1e-52 176.1 1.4 1.5e-51 175.0 1.4 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Imm43 PF15570.6 ORY03265.1 - 0.061 13.3 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 43 G-alpha PF00503.20 ORY03267.1 - 7e-113 377.4 0.9 8.1e-113 377.2 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY03267.1 - 5.1e-15 55.4 0.7 1.4e-09 37.6 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY03267.1 - 5.7e-06 25.9 0.2 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY03267.1 - 0.00074 19.7 0.2 0.55 10.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY03267.1 - 0.018 15.1 0.1 5 7.2 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY03267.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glycos_transf_2 PF00535.26 ORY03269.1 - 1.3e-30 106.4 0.0 1.8e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY03269.1 - 6.2e-08 32.8 0.0 8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORY03269.1 - 0.00053 19.5 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ORY03269.1 - 0.049 14.2 0.0 0.1 13.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 ThrE PF06738.12 ORY03270.1 - 6.5e-41 140.3 20.1 1.7e-37 129.1 0.6 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY03270.1 - 2.2e-12 47.3 26.4 5.7e-09 36.2 13.0 2.2 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE ATP1G1_PLM_MAT8 PF02038.16 ORY03270.1 - 1.5 8.4 3.8 1.2 8.6 0.1 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Cyanate_lyase PF02560.14 ORY03271.1 - 5.2e-35 119.1 0.0 8e-35 118.5 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 ORY03271.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ORY03271.1 - 0.0064 16.5 0.0 0.52 10.4 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix Homeodomain PF00046.29 ORY03271.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain AAA PF00004.29 ORY03274.1 - 3.2e-15 56.7 0.0 2.1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY03274.1 - 1.5e-14 54.4 0.0 3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY03274.1 - 1.9e-11 44.7 0.1 1.3e-10 41.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 ORY03274.1 - 3.2e-11 43.0 0.0 8.3e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain NACHT PF05729.12 ORY03274.1 - 1.3e-06 28.4 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 ORY03274.1 - 6e-06 25.8 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 ORY03274.1 - 1e-05 25.6 0.1 2.8e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 ORY03274.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORY03274.1 - 0.00071 19.9 0.0 0.0027 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY03274.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY03274.1 - 0.003 17.6 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 ORY03274.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 ORY03274.1 - 0.0059 15.8 0.0 0.0097 15.1 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase RNA_helicase PF00910.22 ORY03274.1 - 0.0071 16.7 0.0 0.027 14.8 0.0 2.0 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 ORY03274.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 ORY03274.1 - 0.011 15.4 0.1 0.06 13.1 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 ORY03274.1 - 0.018 14.3 0.0 0.045 13.0 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 ORY03274.1 - 0.023 14.8 0.0 0.2 11.7 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY03274.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY03274.1 - 0.029 13.9 0.0 0.12 11.9 0.0 2.0 2 1 1 3 3 3 0 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 ORY03274.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 ORY03274.1 - 0.065 13.2 0.0 0.41 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY03274.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 ORY03274.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 ORY03274.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY03274.1 - 0.13 12.8 0.3 0.94 10.0 0.1 2.6 2 1 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 ORY03274.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Homeodomain PF00046.29 ORY03276.1 - 2.4e-20 72.1 1.5 4.2e-20 71.3 1.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY03276.1 - 0.029 14.3 1.2 0.078 12.9 0.3 2.1 2 0 0 2 2 2 0 Homeobox KN domain DUF5111 PF17138.4 ORY03276.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5111) Peptidase_M49 PF03571.15 ORY03277.1 - 2.7e-08 32.6 0.9 3.8e-07 28.9 0.2 2.7 2 2 0 2 2 2 1 Peptidase family M49 TIP120 PF08623.10 ORY03277.1 - 0.045 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) C2 PF00168.30 ORY03278.1 - 3.6e-18 65.7 0.0 4.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 ORY03278.1 - 0.035 13.9 0.0 0.051 13.4 0.0 1.4 1 1 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 ORY03279.1 - 2.4e-17 63.1 0.1 2.9e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 C2 domain Eaf7 PF07904.13 ORY03280.1 - 0.00027 21.3 0.3 0.0019 18.6 0.2 2.2 1 1 1 2 2 2 1 Chromatin modification-related protein EAF7 WW PF00397.26 ORY03281.1 - 3e-12 46.4 0.7 5.7e-12 45.5 0.7 1.5 1 0 0 1 1 1 1 WW domain AMP-binding PF00501.28 ORY03283.1 - 3.4e-29 101.7 0.1 6.3e-17 61.3 0.0 3.1 2 1 1 3 3 3 3 AMP-binding enzyme Polysacc_deac_1 PF01522.21 ORY03284.1 - 1.3e-33 115.5 0.0 2.2e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 ORY03284.1 - 0.072 11.2 1.1 0.1 10.7 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Polysacc_deac_1 PF01522.21 ORY03285.1 - 1.4e-33 115.5 0.1 3e-33 114.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Gram_pos_anchor PF00746.21 ORY03285.1 - 0.01 15.8 0.2 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Polysacc_deac_1 PF01522.21 ORY03286.1 - 6.5e-20 71.3 0.1 7.4e-20 71.1 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 ORY03287.1 - 3.6e-34 117.3 0.0 7e-34 116.4 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 ORY03288.1 - 3.1e-33 114.3 0.0 4.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY03288.1 - 0.12 11.6 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 ORY03289.1 - 2.3e-34 117.9 0.0 1.2e-33 115.7 0.0 2.0 2 1 1 3 3 3 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY03289.1 - 0.00097 18.4 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORY03289.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) zf-RAG1 PF10426.9 ORY03289.1 - 0.14 12.3 1.2 4.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain DWNN PF08783.11 ORY03290.1 - 3e-35 120.3 0.0 5.5e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ORY03290.1 - 6.2e-09 35.5 6.6 6.2e-09 35.5 6.6 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 ORY03290.1 - 1e-05 25.3 10.8 1e-05 25.3 10.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 ORY03290.1 - 1.1e-05 25.2 2.4 1.1e-05 25.2 2.4 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-RING_6 PF14835.6 ORY03290.1 - 0.00015 21.5 2.4 0.00031 20.5 2.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 ORY03290.1 - 0.00038 20.3 8.6 0.00038 20.3 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY03290.1 - 0.0047 17.2 9.9 0.0047 17.2 9.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-CCHC_3 PF13917.6 ORY03290.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.0 2 0 0 2 2 2 0 Zinc knuckle Siva PF05458.12 ORY03290.1 - 0.086 12.5 5.8 1.4 8.6 5.8 2.2 1 1 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_UBOX PF13445.6 ORY03290.1 - 0.16 12.0 8.2 0.35 10.9 8.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 ORY03290.1 - 0.53 10.3 16.6 0.034 14.1 9.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 ORY03290.1 - 1.4 8.8 10.5 3.5 7.5 10.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY03290.1 - 2.8 8.2 17.9 0.25 11.5 12.9 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY03290.1 - 5.8 6.9 19.1 0.085 12.7 11.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C_GCAxxG_C_C PF09719.10 ORY03291.1 - 0.046 14.0 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Solute_trans_a PF03619.16 ORY03292.1 - 1.5e-41 142.7 18.2 1.8e-41 142.4 18.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Yip1 PF04893.17 ORY03292.1 - 1.9 8.2 14.2 0.3 10.8 2.2 3.1 1 1 1 2 2 2 0 Yip1 domain CBAH PF02275.18 ORY03293.1 - 0.014 15.1 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family COG5 PF10392.9 ORY03294.1 - 0.044 14.0 0.3 0.14 12.3 0.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V-ATPase_G PF03179.15 ORY03294.1 - 0.57 10.7 3.1 0.43 11.1 0.5 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Helicase_C PF00271.31 ORY03295.1 - 9.4e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Transket_pyr PF02779.24 ORY03344.1 - 2.5e-48 164.1 0.0 3.9e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORY03344.1 - 8.5e-47 158.7 0.0 1.5e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORY03344.1 - 4.6e-41 140.7 0.2 2e-40 138.7 0.0 1.9 2 0 0 2 2 2 1 Dehydrogenase E1 component TauD PF02668.16 ORY03345.1 - 1.4e-57 195.5 2.6 1.8e-57 195.2 2.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family YebG PF07130.12 ORY03345.1 - 0.13 12.1 0.3 0.3 11.0 0.3 1.7 1 0 0 1 1 1 0 YebG protein MFS_1 PF07690.16 ORY03346.1 - 1.2e-29 103.4 20.5 1.8e-28 99.5 21.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.6 ORY03346.1 - 0.058 13.2 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Pox_EPC_I2-L1 PF12575.8 ORY03346.1 - 0.11 12.7 0.3 1.7 8.9 0.1 2.9 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 CGI-121 PF08617.10 ORY03347.1 - 3.7e-39 134.4 0.1 4.2e-39 134.3 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Phage_holin_3_1 PF05106.12 ORY03347.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Aa_trans PF01490.18 ORY03349.1 - 5.6e-55 186.7 39.0 6.5e-55 186.5 39.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY03349.1 - 0.00011 21.1 51.1 0.00077 18.4 51.1 2.0 1 1 0 1 1 1 1 Amino acid permease Ribosomal_S6e PF01092.19 ORY03350.1 - 1.8e-45 153.9 0.0 3.9e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e STIL_N PF15253.6 ORY03351.1 - 0.0074 15.3 1.0 0.02 13.9 0.0 2.1 3 0 0 3 3 3 1 SCL-interrupting locus protein N-terminus FtsJ PF01728.19 ORY03353.1 - 2.2e-56 190.8 0.0 2.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase IF-2B PF01008.17 ORY03354.1 - 3.4e-30 105.2 0.3 9.9e-30 103.7 0.3 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 ORY03354.1 - 2.5e-05 24.3 0.2 0.00011 22.3 0.3 1.9 2 0 0 2 2 2 1 NUDIX domain Urb2 PF10441.9 ORY03354.1 - 0.15 12.0 0.2 0.27 11.2 0.2 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family PTPA PF03095.15 ORY03355.1 - 3.2e-125 417.6 0.0 3.7e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF936 PF06075.12 ORY03355.1 - 0.019 13.9 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DDHD PF02862.17 ORY03356.1 - 7.6e-35 121.1 0.1 1e-34 120.7 0.1 1.2 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 ORY03356.1 - 0.092 12.2 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Vps8 PF12816.7 ORY03357.1 - 7.1e-56 188.9 0.1 4.7e-53 179.6 0.0 2.7 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 ORY03357.1 - 1.6e-05 24.8 3.0 0.0061 16.4 0.0 3.9 5 0 0 5 5 5 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 ORY03357.1 - 0.02 15.2 0.0 0.65 10.3 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_11 PF17123.5 ORY03357.1 - 0.15 11.8 0.6 0.36 10.6 0.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 ORY03357.1 - 0.5 10.7 4.1 0.22 11.9 0.4 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 ORY03357.1 - 6.1 6.8 5.2 3.1 7.7 0.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.19 ORY03358.1 - 7.5e-136 453.0 0.0 1.6e-132 442.0 0.0 2.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 ORY03358.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain zf-C2H2 PF00096.26 ORY03359.1 - 1.2e-11 44.4 11.3 1.2e-05 25.5 3.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY03359.1 - 6.4e-11 42.2 13.5 1.5e-07 31.5 1.4 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY03359.1 - 1.2e-09 38.2 9.4 7.8e-05 23.2 2.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY03359.1 - 1.1e-05 25.6 1.9 1.1e-05 25.6 1.9 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY03359.1 - 6.5e-05 22.8 7.3 7.8e-05 22.6 1.8 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY03359.1 - 0.0002 21.5 2.4 0.0017 18.6 0.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY03359.1 - 0.0047 17.2 2.0 0.034 14.4 0.2 2.0 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORY03359.1 - 0.0094 15.7 6.5 0.15 11.9 0.3 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORY03359.1 - 0.017 15.5 1.6 0.095 13.0 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 ORY03359.1 - 0.017 15.4 3.4 1.4 9.2 0.3 2.2 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 ORY03359.1 - 0.035 14.2 0.5 0.056 13.6 0.1 1.4 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 ORY03359.1 - 0.63 10.0 8.0 3 7.8 3.0 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 ORY03360.1 - 5e-14 51.9 7.7 4.8e-07 29.9 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03360.1 - 6.6e-10 39.0 6.5 9.4e-05 22.9 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY03360.1 - 9.2e-10 38.5 12.8 4.3e-07 30.1 0.3 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY03360.1 - 3.7e-05 23.6 4.4 0.0091 16.0 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY03360.1 - 3.8e-05 23.8 2.0 0.00023 21.3 0.9 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY03360.1 - 0.00061 20.1 0.8 0.00061 20.1 0.8 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-BED PF02892.15 ORY03360.1 - 0.0023 17.9 2.3 0.05 13.6 2.3 2.2 1 1 0 1 1 1 1 BED zinc finger zf-C2H2_11 PF16622.5 ORY03360.1 - 0.0029 17.3 7.1 0.17 11.7 0.6 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 ORY03360.1 - 0.0089 16.3 0.3 0.012 15.9 0.3 1.3 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 ORY03360.1 - 0.01 16.1 0.4 0.11 12.8 0.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 ORY03360.1 - 0.014 15.3 3.8 0.26 11.2 0.6 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 ORY03360.1 - 0.019 15.1 1.0 3.8 7.7 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 ORY03360.1 - 0.023 14.6 3.4 2.3 8.2 0.1 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 ORY03360.1 - 0.026 14.7 0.1 0.031 14.4 0.0 1.2 1 1 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_3rep PF18868.1 ORY03360.1 - 0.03 15.0 1.8 1.9 9.2 0.3 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 ORY03360.1 - 0.033 14.1 0.4 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger CCAP PF11105.8 ORY03360.1 - 0.11 12.4 0.2 0.11 12.4 0.2 1.0 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a EF-hand_1 PF00036.32 ORY03361.1 - 4.2e-28 94.8 13.9 6.8e-07 28.4 0.2 5.8 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 ORY03361.1 - 1e-22 78.0 8.8 4.7e-06 26.1 0.1 5.1 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 ORY03361.1 - 1.9e-22 79.5 6.9 3.2e-09 37.1 0.1 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 ORY03361.1 - 5.6e-20 70.9 7.2 1.4e-11 44.0 0.1 4.1 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 ORY03361.1 - 3.3e-17 61.1 10.8 1.2e-05 24.6 0.0 4.9 5 0 0 5 5 5 4 EF hand DUF5640 PF18692.1 ORY03361.1 - 0.031 14.3 1.3 0.061 13.4 0.9 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5640) GUN4 PF05419.12 ORY03361.1 - 0.049 13.7 0.0 0.086 12.9 0.0 1.4 1 1 0 1 1 1 0 GUN4-like EF-hand_4 PF12763.7 ORY03361.1 - 0.17 11.9 1.8 1.5 8.8 0.2 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORY03362.1 - 4.8e-26 88.3 11.4 2.7e-05 23.4 0.1 6.6 6 1 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 ORY03362.1 - 6.2e-24 81.8 10.1 3.5e-07 29.6 0.1 5.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 ORY03362.1 - 2.7e-23 82.2 5.4 2e-10 41.0 0.0 4.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY03362.1 - 9.4e-20 69.2 12.5 1e-06 27.9 0.0 5.5 5 1 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORY03362.1 - 1.8e-19 69.3 5.2 3.1e-10 39.7 0.0 5.0 3 3 2 5 5 5 5 EF-hand domain pair EF-hand_9 PF14658.6 ORY03362.1 - 0.0035 17.6 0.1 7.9 6.9 0.0 3.6 4 1 0 4 4 4 1 EF-hand domain PPR_2 PF13041.6 ORY03363.1 - 1.7e-121 396.3 30.9 8.2e-16 57.9 0.0 14.8 4 2 11 15 15 15 12 PPR repeat family PPR_1 PF12854.7 ORY03363.1 - 5e-81 266.1 7.7 3.3e-09 36.3 0.0 12.1 13 0 0 13 13 13 9 PPR repeat PPR PF01535.20 ORY03363.1 - 1.4e-76 247.5 29.3 1.3e-07 31.4 0.0 15.7 16 0 0 16 16 15 10 PPR repeat PPR_3 PF13812.6 ORY03363.1 - 3.2e-70 232.1 9.8 6.7e-13 48.5 0.1 9.8 8 2 2 10 10 10 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY03363.1 - 3.2e-46 157.4 0.1 1.3e-10 41.1 0.0 6.1 2 2 4 6 6 6 6 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 ORY03363.1 - 8e-15 54.6 2.1 0.00035 19.6 0.0 5.4 1 1 4 5 5 5 4 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 ORY03363.1 - 6.7e-12 45.9 7.9 0.011 16.1 1.8 7.5 3 2 7 10 10 10 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORY03363.1 - 1.3e-08 34.9 0.0 8.3 7.5 0.0 7.5 4 2 4 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03363.1 - 4.4e-07 30.3 0.0 2.4 8.7 0.0 6.5 6 3 1 7 7 7 1 Tetratricopeptide repeat ATP13 PF12921.7 ORY03363.1 - 1.1e-06 28.5 4.5 1.5 8.7 0.0 6.9 4 2 3 7 7 7 1 Mitochondrial ATPase expression ECSIT PF06239.11 ORY03363.1 - 2.4e-06 26.8 2.2 1.8 7.7 0.0 7.0 2 2 5 8 8 8 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 ORY03363.1 - 5.2e-05 23.0 0.1 13 6.1 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat AEP1 PF17049.5 ORY03363.1 - 0.00012 21.3 10.3 0.097 11.7 0.0 5.0 2 1 3 6 6 6 2 ATPase expression protein 1 Ribonuc_red_lgN PF00317.21 ORY03363.1 - 0.0019 18.2 1.5 8.4 6.5 0.0 5.5 4 3 0 4 4 4 0 Ribonucleotide reductase, all-alpha domain Hemocyanin_N PF03722.14 ORY03363.1 - 0.0046 17.5 1.1 1.4 9.4 0.0 4.5 5 0 0 5 5 4 1 Hemocyanin, all-alpha domain ANAPC3 PF12895.7 ORY03363.1 - 0.0055 16.9 0.1 5.1 7.4 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TAP_C PF03943.13 ORY03363.1 - 0.015 14.9 0.5 32 4.3 0.0 6.0 9 0 0 9 9 9 0 TAP C-terminal domain SPOB_a PF14689.6 ORY03363.1 - 0.025 14.3 0.2 21 4.9 0.0 4.5 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain Vps39_1 PF10366.9 ORY03363.1 - 0.026 14.8 0.3 7.6 6.9 0.2 4.1 2 2 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 ORY03363.1 - 0.035 13.9 0.2 32 4.6 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat DEP PF00610.21 ORY03363.1 - 0.044 13.9 0.1 4.7 7.3 0.0 3.8 3 1 1 4 4 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Clathrin PF00637.20 ORY03363.1 - 0.052 13.4 10.0 9.8 6.0 0.0 5.5 3 2 2 6 6 6 0 Region in Clathrin and VPS RhoGAP-FF1 PF16512.5 ORY03363.1 - 0.061 14.0 0.3 96 3.8 0.0 4.3 4 0 0 4 4 3 0 p190-A and -B Rho GAPs FF domain TetR_C_19 PF17924.1 ORY03363.1 - 0.53 10.9 5.0 34 5.1 0.0 4.9 5 0 0 5 5 3 0 Tetracyclin repressor-like, C-terminal domain PH PF00169.29 ORY03364.1 - 4.5e-14 52.8 0.0 5.9e-07 29.9 0.1 2.7 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 ORY03364.1 - 3.8e-07 30.5 0.1 4.3e-06 27.1 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain AA_kinase PF00696.28 ORY03365.1 - 7.7e-24 84.6 1.1 5e-22 78.7 0.1 2.2 1 1 1 2 2 2 2 Amino acid kinase family PUA PF01472.20 ORY03365.1 - 5.4e-09 35.9 1.5 9.5e-09 35.1 0.4 2.1 2 0 0 2 2 2 1 PUA domain Moricin PF06451.11 ORY03365.1 - 0.26 11.1 0.8 1.4 8.8 0.1 2.5 3 0 0 3 3 3 0 Moricin AA_kinase PF00696.28 ORY03366.1 - 2.3e-41 142.0 1.0 3.2e-41 141.5 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY03366.1 - 8.3e-09 35.3 1.3 1.4e-08 34.6 0.2 2.0 2 0 0 2 2 2 1 PUA domain Orexin_rec2 PF03827.13 ORY03366.1 - 0.13 12.3 0.3 0.3 11.1 0.3 1.6 1 0 0 1 1 1 0 Orexin receptor type 2 AA_kinase PF00696.28 ORY03367.1 - 1.5e-31 109.8 2.4 2e-31 109.4 2.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY03367.1 - 4.4e-09 36.2 0.2 1.3e-08 34.6 0.2 1.9 1 0 0 1 1 1 1 PUA domain PH_17 PF18012.1 ORY03367.1 - 0.15 11.8 0.1 12 5.8 0.0 2.7 3 0 0 3 3 3 0 PH domain Moricin PF06451.11 ORY03367.1 - 0.3 10.9 1.9 1.2 9.0 0.1 2.8 3 1 0 3 3 3 0 Moricin CBM_19 PF03427.13 ORY03368.1 - 0.0092 15.9 2.2 0.016 15.2 2.2 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) Collagen PF01391.18 ORY03371.1 - 1.5e-24 85.5 75.3 6.2e-07 29.1 23.6 4.8 3 1 1 4 4 4 1 Collagen triple helix repeat (20 copies) CBM_19 PF03427.13 ORY03371.1 - 0.017 15.1 2.1 0.027 14.5 2.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) CBM_19 PF03427.13 ORY03373.1 - 0.00046 20.1 0.6 0.00077 19.4 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) AAA_lid_2 PF17863.1 ORY03375.1 - 2e-11 43.5 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain DUF4460 PF14687.6 ORY03375.1 - 3.6e-10 39.9 0.7 2.1e-09 37.4 0.2 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4460) Syntaxin-6_N PF09177.11 ORY03375.1 - 0.034 14.7 1.1 1.8 9.2 0.1 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Metallopep PF12044.8 ORY03376.1 - 3e-132 441.2 0.0 3.9e-132 440.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 ORY03376.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORY03376.1 - 0.058 13.2 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Matrixin PQQ_2 PF13360.6 ORY03377.1 - 0.078 12.5 0.1 0.17 11.4 0.1 1.5 1 1 0 1 1 1 0 PQQ-like domain ComX PF05952.12 ORY03377.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Pkinase PF00069.25 ORY03378.1 - 1.4e-58 198.4 0.0 1.6e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03378.1 - 9.1e-30 103.8 0.0 1.2e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY03378.1 - 3.2e-12 46.4 0.0 7.4e-12 45.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY03378.1 - 7.2e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY03378.1 - 2.5e-05 24.3 0.1 0.019 14.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY03378.1 - 6.9e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY03378.1 - 0.0006 18.9 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY03378.1 - 0.007 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 ORY03378.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family MCM PF00493.23 ORY03379.1 - 2.6e-104 347.2 0.5 1.3e-103 345.0 0.1 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 ORY03379.1 - 7e-35 119.6 0.1 1.4e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY03379.1 - 4.8e-30 103.8 0.5 1.6e-29 102.2 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY03379.1 - 3.9e-17 62.7 0.4 9.4e-17 61.5 0.4 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY03379.1 - 3e-05 23.5 0.0 0.0002 20.8 0.0 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY03379.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY03379.1 - 0.02 14.9 0.0 0.065 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Cpn60_TCP1 PF00118.24 ORY03380.1 - 3.2e-158 527.4 19.1 3.6e-158 527.2 19.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3767 PF12597.8 ORY03381.1 - 3.2e-33 113.6 0.0 4.1e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Ribosomal_L11_N PF03946.14 ORY03383.1 - 1.5e-24 85.6 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY03383.1 - 3e-17 62.9 0.2 6.2e-17 61.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L27e PF01777.18 ORY03384.1 - 1.8e-36 124.4 7.4 1.8e-36 124.4 7.4 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 ORY03384.1 - 0.00015 21.5 1.5 0.00033 20.5 1.5 1.6 1 0 0 1 1 1 1 KOW motif DEAD PF00270.29 ORY03385.1 - 2.4e-45 154.4 0.4 4.2e-45 153.6 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY03385.1 - 4.1e-33 114.0 0.1 1.1e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY03385.1 - 6.4e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY03385.1 - 4.4e-05 23.8 0.1 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY03385.1 - 0.00032 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 ORY03385.1 - 0.0072 15.2 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 ORY03385.1 - 0.013 15.4 0.5 0.051 13.5 0.1 2.3 2 1 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 ORY03385.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 ORY03385.1 - 0.077 12.5 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 ORY03385.1 - 0.085 13.1 0.4 0.35 11.1 0.4 1.9 1 1 0 1 1 1 0 AAA domain PS_Dcarbxylase PF02666.15 ORY03386.1 - 4.7e-71 238.5 0.0 2.4e-55 187.2 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase DAD PF02109.16 ORY03387.1 - 1e-42 144.8 2.8 1.1e-42 144.7 2.8 1.0 1 0 0 1 1 1 1 DAD family ATP-synt_Eps PF04627.13 ORY03388.1 - 5.9e-22 77.4 3.6 7.9e-22 77.0 3.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain HSP20 PF00011.21 ORY03389.1 - 4.5e-12 46.0 0.1 2.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY03389.1 - 1.8e-07 30.6 0.0 3.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Cyclin PF08613.11 ORY03391.1 - 3.4e-12 47.0 0.7 1.1e-11 45.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY03391.1 - 0.018 14.8 0.3 0.041 13.6 0.3 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Chitin_synth_2 PF03142.15 ORY03392.1 - 1.2e-246 819.4 0.2 1.6e-246 819.0 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY03392.1 - 2.5e-131 439.1 5.4 4e-131 438.4 5.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY03392.1 - 4.7e-15 55.2 0.1 2.1e-14 53.1 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORY03392.1 - 3.3e-11 43.5 0.0 1.2e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY03392.1 - 7.8e-09 35.7 3.9 7.8e-09 35.7 3.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 ORY03392.1 - 1.6e-08 34.6 0.1 2.7e-05 24.2 0.0 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY03392.1 - 4.2e-05 23.4 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 ORY03392.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_transf_21 PF13506.6 ORY03392.1 - 0.1 12.1 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 GCS PF03074.16 ORY03394.1 - 1.2e-183 610.5 0.1 1.7e-183 610.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase AIRC PF00731.20 ORY03395.1 - 1.2e-63 213.2 1.1 2.8e-63 211.9 1.1 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 ORY03395.1 - 9.1e-60 201.1 0.0 1.5e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ORY03395.1 - 1.2e-20 72.9 0.0 2.3e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 ORY03395.1 - 1.3e-08 34.6 0.2 7.3e-08 32.2 0.0 2.3 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 ORY03395.1 - 2e-07 30.8 0.1 1.9e-06 27.6 0.1 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 ORY03395.1 - 0.0033 17.0 0.9 0.16 11.6 0.1 2.5 2 0 0 2 2 2 1 Propionate catabolism activator F420_oxidored PF03807.17 ORY03395.1 - 0.0078 16.8 0.2 0.065 13.8 0.1 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ORY03395.1 - 0.029 13.7 0.4 0.11 11.8 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY03395.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY03395.1 - 0.077 12.9 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 ORY03395.1 - 0.14 12.6 0.8 2 8.9 0.0 2.8 3 1 0 3 3 3 0 CoA binding domain Pribosyltran PF00156.27 ORY03396.1 - 9.5e-11 41.5 0.1 2.8e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Como_LCP PF02247.16 ORY03396.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Large coat protein Peptidase_M17 PF00883.21 ORY03397.1 - 2.1e-63 214.5 0.0 2.6e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pantoate_ligase PF02569.15 ORY03398.1 - 2.4e-100 335.2 0.0 2.7e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Alpha-amylase_C PF02806.18 ORY03399.1 - 7e-26 90.5 0.0 2e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 ORY03399.1 - 6.4e-21 74.5 0.0 1.3e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY03399.1 - 5.1e-16 59.2 0.6 1.4e-13 51.1 0.6 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Arrestin_C PF02752.22 ORY03400.1 - 3.1e-12 47.1 0.1 5.5e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY03400.1 - 6.2e-05 23.1 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PRP3 PF08572.10 ORY03401.1 - 6.1e-76 255.1 6.8 6.1e-76 255.1 6.8 2.1 3 0 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ORY03401.1 - 1.5e-44 151.6 0.2 1.5e-44 151.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF2407 PF10302.9 ORY03401.1 - 0.6 10.7 2.9 1.9 9.1 0.0 3.0 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain AAA PF00004.29 ORY03402.1 - 1.4e-43 148.5 0.0 2.4e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY03402.1 - 7.9e-25 86.6 0.0 3.5e-24 84.6 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORY03402.1 - 2.8e-24 84.9 5.3 6.4e-24 83.8 5.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORY03402.1 - 2.4e-08 33.7 0.0 6.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY03402.1 - 6.8e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY03402.1 - 1.6e-05 25.3 0.0 0.0018 18.7 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORY03402.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY03402.1 - 4.8e-05 22.7 0.0 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 ORY03402.1 - 5.6e-05 23.2 0.0 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY03402.1 - 7e-05 23.1 0.1 0.0066 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY03402.1 - 7e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY03402.1 - 0.00037 20.9 0.0 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 ORY03402.1 - 0.00038 19.7 0.0 0.0007 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY03402.1 - 0.00052 20.6 0.2 0.0019 18.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 ORY03402.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY03402.1 - 0.0013 18.9 0.1 0.0052 16.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 ORY03402.1 - 0.0027 17.5 0.3 0.0099 15.6 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 ORY03402.1 - 0.0093 16.4 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY03402.1 - 0.025 14.1 0.1 0.72 9.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY03402.1 - 0.03 13.8 0.0 0.094 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 ORY03402.1 - 0.038 13.8 0.0 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 ORY03402.1 - 0.04 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY03402.1 - 0.045 13.7 0.0 0.73 9.7 0.0 2.4 1 1 1 2 2 2 0 NACHT domain USP8_dimer PF08969.11 ORY03402.1 - 0.057 13.6 5.9 0.12 12.6 5.9 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Torsin PF06309.11 ORY03402.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin PhoH PF02562.16 ORY03402.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ORY03402.1 - 0.076 12.3 0.1 8.9 5.6 0.0 2.3 1 1 1 2 2 2 0 KaiC TniB PF05621.11 ORY03402.1 - 0.079 12.4 0.0 14 5.0 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 ORY03402.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 ORY03402.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORY03402.1 - 0.16 11.7 0.0 0.53 10.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 ORY03402.1 - 0.48 10.3 3.4 1.8 8.4 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TPR_2 PF07719.17 ORY03402.1 - 0.7 10.2 3.7 1.1 9.6 0.5 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Arrestin_C PF02752.22 ORY03403.1 - 7.8e-11 42.6 0.2 1.1e-06 29.1 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY03403.1 - 6.3e-07 29.5 0.0 1.7e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4413 PF14372.6 ORY03403.1 - 0.12 12.7 0.1 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) LAG1-DNAbind PF09271.11 ORY03425.1 - 2.8e-27 96.2 2.0 1.9e-25 90.3 2.0 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 ORY03425.1 - 5.2e-21 75.5 0.0 8.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Cation_ATPase_C PF00689.21 ORY03426.1 - 1.4e-43 148.7 13.8 1.4e-43 148.7 13.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY03426.1 - 7.4e-35 120.1 1.8 7.4e-35 120.1 1.8 3.8 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY03426.1 - 1.6e-21 76.1 0.0 3.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY03426.1 - 1.4e-19 71.2 0.0 3.3e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY03426.1 - 2.2e-10 40.1 1.4 1.5e-09 37.4 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY03426.1 - 8.2e-05 22.5 0.7 0.0025 17.6 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cyt-b5 PF00173.28 ORY03427.1 - 7e-27 93.4 0.0 9.1e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain tRNA-synt_1b PF00579.25 ORY03429.1 - 3.1e-21 76.0 0.0 4.6e-20 72.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HATPase_c PF02518.26 ORY03430.1 - 3.7e-28 98.3 0.2 8.1e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY03430.1 - 4.8e-21 75.0 0.6 9.3e-17 61.2 0.3 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 ORY03430.1 - 4e-15 55.6 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF561 PF04481.12 ORY03430.1 - 0.13 11.4 0.1 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) SH3_9 PF14604.6 ORY03431.1 - 1.8e-08 34.1 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY03431.1 - 1.2e-07 31.3 0.0 2.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Band_7 PF01145.25 ORY03432.1 - 1.2e-24 87.3 8.3 1.5e-24 87.0 6.3 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family Tma16 PF11176.8 ORY03433.1 - 1.7e-44 151.3 4.6 2e-44 151.0 4.6 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 RRM_1 PF00076.22 ORY03434.1 - 4.1e-14 52.2 0.0 1.3e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spindle_Spc25 PF08234.12 ORY03435.1 - 1.1e-22 80.0 0.1 2.5e-22 78.8 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 RNA_bind PF08675.11 ORY03435.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 RNA binding domain AKNA PF12443.8 ORY03435.1 - 0.15 12.7 3.2 0.66 10.7 1.5 2.5 1 1 0 2 2 2 0 AT-hook-containing transcription factor F1F0-ATPsyn_F PF10791.9 ORY03436.1 - 1.4e-17 63.9 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WD40 PF00400.32 ORY03437.1 - 1.1e-15 57.7 3.6 3e-06 27.9 0.3 6.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORY03437.1 - 2.1e-08 33.7 12.2 2.1e-08 33.7 12.2 2.9 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 ORY03437.1 - 0.00052 20.3 1.2 0.92 9.8 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORY03437.1 - 0.039 14.0 0.1 0.79 9.8 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Drf_GBD PF06371.13 ORY03437.1 - 0.056 13.0 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Rep_fac-A_C PF08646.10 ORY03437.1 - 0.31 10.8 4.9 0.76 9.5 4.9 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain Rhodanese_C PF12368.8 ORY03437.1 - 4.1 7.9 7.8 10 6.6 7.8 1.7 1 0 0 1 1 1 0 Rhodanase C-terminal SSXT PF05030.12 ORY03438.1 - 8.1e-14 51.0 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Ribosomal_S14 PF00253.21 ORY03439.1 - 1e-15 57.2 4.8 1.1e-15 57.1 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ORY03439.1 - 0.032 14.2 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Ribosomal_S7 PF00177.21 ORY03440.1 - 1e-37 129.0 0.8 1.3e-37 128.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ras PF00071.22 ORY03441.1 - 2.5e-51 173.5 0.0 3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY03441.1 - 3.1e-17 62.9 0.0 4.6e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY03441.1 - 4.1e-10 39.4 0.0 4.8e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY03441.1 - 0.00073 19.1 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY03441.1 - 0.003 17.5 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY03441.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORY03441.1 - 0.041 13.9 0.0 0.076 13.0 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 ORY03441.1 - 0.059 13.7 0.0 1.5 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY03441.1 - 0.14 12.4 0.1 3.1 8.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY03441.1 - 0.18 11.0 0.1 1.6 7.8 0.0 2.1 2 1 0 2 2 2 0 NB-ARC domain Ribosomal_L37ae PF01780.19 ORY03442.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORY03442.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORY03442.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORY03442.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORY03442.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Tetraspanin PF00335.20 ORY03443.1 - 1.8e-06 27.9 0.3 3.8e-06 26.8 0.4 1.5 1 1 1 2 2 2 1 Tetraspanin family Tachystatin_B PF11478.8 ORY03443.1 - 0.92 9.5 5.1 1.3 9.0 3.3 2.1 1 1 1 2 2 2 0 Antimicrobial chitin binding protein tachystatin B hNIFK_binding PF12196.8 ORY03444.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Polysacc_deac_1 PF01522.21 ORY03445.1 - 2.9e-33 114.4 0.0 4.2e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY03445.1 - 0.0028 16.9 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 SET PF00856.28 ORY03446.1 - 8e-08 32.9 0.2 3.1e-07 30.9 0.1 2.1 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 ORY03446.1 - 8.3e-06 25.8 5.4 2.2e-05 24.5 5.4 1.7 1 0 0 1 1 1 1 MYND finger Polysacc_deac_1 PF01522.21 ORY03447.1 - 6.2e-28 97.2 0.0 8.2e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY03447.1 - 3.4e-08 33.8 22.5 8.2e-08 32.6 22.5 1.7 1 0 0 1 1 1 1 Chitin recognition protein Isochorismatase PF00857.20 ORY03448.1 - 8.9e-33 113.9 0.0 1e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_5 PF13444.6 ORY03451.1 - 2.4e-07 31.4 0.0 3.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY03451.1 - 2.3e-05 24.3 0.0 0.00045 20.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY03451.1 - 0.00019 21.6 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY03451.1 - 0.00021 21.4 0.0 0.033 14.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain MttA_Hcf106 PF02416.16 ORY03500.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family PH_12 PF16457.5 ORY03501.1 - 0.056 14.0 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain HTH_19 PF12844.7 ORY03501.1 - 0.15 12.1 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain ADH_zinc_N_2 PF13602.6 ORY03502.1 - 1e-16 62.2 0.0 1.8e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY03502.1 - 3.4e-14 53.0 0.0 5.2e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY03502.1 - 3e-09 36.7 0.0 8.7e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORY03502.1 - 0.0046 17.2 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 ORY03502.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_N PF08240.12 ORY03503.1 - 3.1e-23 81.7 3.4 4.1e-23 81.4 2.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY03503.1 - 3e-19 69.3 0.0 4.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY03503.1 - 1.2e-05 24.8 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY03503.1 - 3.2e-05 23.3 0.1 4.8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY03503.1 - 0.0051 17.9 0.0 0.0077 17.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GFO_IDH_MocA PF01408.22 ORY03503.1 - 0.0083 16.9 0.0 0.015 16.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 ORY03503.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ubie_methyltran PF01209.18 ORY03504.1 - 8e-15 54.8 0.0 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY03504.1 - 7.1e-13 49.1 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY03504.1 - 2.8e-12 47.1 0.0 5.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY03504.1 - 3.3e-08 33.5 0.0 7.1e-08 32.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY03504.1 - 4.9e-08 33.0 0.0 8.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY03504.1 - 0.0037 18.0 0.0 0.013 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY03504.1 - 0.0057 16.2 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain SOBP PF15279.6 ORY03505.1 - 0.04 14.5 4.7 0.046 14.3 4.0 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein GPR_Gpa2_C PF11970.8 ORY03506.1 - 0.004 17.2 0.1 0.0067 16.5 0.1 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Phage_TAC_12 PF12363.8 ORY03507.1 - 0.16 12.4 0.1 0.57 10.6 0.1 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Zip PF02535.22 ORY03508.1 - 1.6e-54 185.4 15.7 2.5e-54 184.7 15.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter zf-H2C2_2 PF13465.6 ORY03509.1 - 2.7e-14 52.8 7.8 3.1e-09 36.8 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY03509.1 - 6.1e-08 32.7 7.7 7.5e-05 23.0 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03509.1 - 1.4e-07 31.8 5.8 0.00088 19.9 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY03509.1 - 8.6e-05 22.7 3.7 0.18 12.2 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 ORY03509.1 - 0.00027 21.6 2.6 0.0052 17.5 0.2 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORY03509.1 - 0.00081 19.7 3.3 0.25 11.8 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY03509.1 - 0.0095 15.7 1.3 0.0095 15.7 1.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 ORY03509.1 - 0.042 13.9 5.2 3.1 7.9 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PyrI_C PF02748.15 ORY03509.1 - 0.044 13.7 1.6 5.2 7.0 0.3 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 ORY03509.1 - 0.095 12.9 2.9 9.2 6.5 0.2 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger YyzF PF14116.6 ORY03509.1 - 0.3 11.2 1.9 6.8 6.8 0.4 2.4 2 0 0 2 2 2 0 YyzF-like protein DUF1272 PF06906.11 ORY03509.1 - 0.47 10.6 4.0 11 6.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) C1_4 PF07975.12 ORY03509.1 - 0.57 10.5 9.0 0.58 10.4 4.1 2.8 2 1 2 4 4 4 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 ORY03509.1 - 0.73 10.0 4.9 9 6.5 0.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 ORY03509.1 - 1.9 8.6 9.4 3.1 7.9 6.5 2.4 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.26 ORY03510.1 - 7.1e-10 38.8 11.0 3.9e-06 27.0 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03510.1 - 2.2e-07 31.1 9.5 0.0004 21.0 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY03510.1 - 1e-06 28.8 14.9 1.5e-06 28.3 2.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY03510.1 - 4.3e-05 23.7 3.3 0.15 12.4 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY03510.1 - 0.16 12.4 2.9 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY03510.1 - 0.16 12.0 6.3 1.3 9.1 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.12 ORY03510.1 - 0.27 11.5 0.2 0.27 11.5 0.2 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain PyrI_C PF02748.15 ORY03510.1 - 0.4 10.6 3.1 13 5.8 0.3 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FAM195 PF14799.6 ORY03511.1 - 0.076 13.4 2.7 2.9 8.3 0.2 4.1 3 0 0 3 3 3 0 FAM195 family Ferlin_C PF16165.5 ORY03511.1 - 3.4 7.6 6.3 1.1 9.2 1.1 2.7 2 0 0 2 2 2 0 Ferlin C-terminus Pyr_redox_2 PF07992.14 ORY03512.1 - 1.4e-27 96.7 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY03512.1 - 5.2e-09 36.6 0.4 9.9e-05 22.8 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY03512.1 - 0.00046 20.2 0.3 0.21 11.6 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY03512.1 - 0.001 18.4 0.1 0.17 11.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY03512.1 - 0.003 17.2 0.1 0.11 12.0 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY03512.1 - 0.0069 15.1 0.1 0.2 10.3 0.0 3.0 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 ORY03512.1 - 0.015 14.3 0.0 0.043 12.9 0.0 1.7 1 1 1 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY03512.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Glu_dehyd_C PF16912.5 ORY03512.1 - 0.095 12.2 0.2 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 ORY03512.1 - 0.16 12.5 1.1 14 6.2 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding RRM_1 PF00076.22 ORY03513.1 - 1.7e-31 107.8 0.0 2.8e-15 55.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORY03513.1 - 8.2e-26 88.2 0.2 1e-05 24.9 0.0 6.3 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 ORY03513.1 - 1.2e-11 44.3 0.0 3e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY03513.1 - 5e-05 22.9 0.0 0.06 12.9 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.9 ORY03513.1 - 0.0016 18.0 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 RNA-recognition motif RRM_8 PF11835.8 ORY03513.1 - 0.0068 16.6 0.0 0.089 13.0 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain SET_assoc PF11767.8 ORY03513.1 - 0.081 12.6 0.2 0.29 10.8 0.0 2.0 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 ORY03513.1 - 0.086 12.9 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 Pribosyl_synth PF14572.6 ORY03515.1 - 3e-43 148.0 1.6 3.1e-41 141.4 1.6 2.2 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY03515.1 - 5.9e-43 145.5 1.7 2.7e-42 143.4 0.1 2.4 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY03515.1 - 3e-09 36.6 0.1 5.6e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain O-FucT PF10250.9 ORY03515.1 - 0.04 13.6 0.0 8.4 6.0 0.0 2.1 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase zf-H2C2_2 PF13465.6 ORY03516.1 - 1.8e-10 40.7 9.1 2.1e-09 37.4 0.3 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY03516.1 - 2.4e-08 34.0 11.4 2.2e-06 27.8 4.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03516.1 - 3.1e-08 33.8 9.6 2.3e-05 24.9 3.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY03516.1 - 4.7e-06 26.8 3.9 0.036 14.4 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY03516.1 - 4e-05 23.8 3.4 0.071 13.5 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY03516.1 - 0.0022 17.7 6.1 0.0085 15.8 1.7 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-Di19 PF05605.12 ORY03516.1 - 0.019 15.3 2.8 0.022 15.0 2.8 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.9 ORY03516.1 - 0.03 14.4 1.6 5.8 7.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 ORY03516.1 - 0.088 13.1 4.9 2.8 8.3 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2225 PF09986.9 ORY03516.1 - 0.088 12.5 1.1 2.1 8.0 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2HC_2 PF13913.6 ORY03516.1 - 0.14 12.1 8.0 0.62 10.0 1.6 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 ORY03516.1 - 1 9.2 14.6 0.11 12.2 9.2 2.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 ORY03516.1 - 3.4 7.9 9.9 2.3 8.5 3.8 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger ACOX PF01756.19 ORY03517.1 - 3.2e-53 180.0 0.0 5.7e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY03517.1 - 1.7e-19 69.8 0.1 2.9e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORY03517.1 - 7.3e-16 58.9 0.0 1.8e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORY03517.1 - 3.2e-07 30.7 0.1 1.6e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CorA PF01544.18 ORY03518.1 - 4.4e-45 154.2 0.8 5e-45 154.0 0.8 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.6 ORY03518.1 - 0.044 14.4 1.7 0.41 11.3 0.1 2.3 2 0 0 2 2 2 0 ACT domain ACOX PF01756.19 ORY03519.1 - 3.2e-53 180.0 0.0 5.7e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY03519.1 - 1.7e-19 69.8 0.1 2.9e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORY03519.1 - 6.9e-15 55.7 0.0 1.7e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORY03519.1 - 2.8e-07 30.9 0.2 1.5e-06 28.5 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Myosin_head PF00063.21 ORY03520.1 - 6.7e-266 883.8 0.3 1e-265 883.2 0.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY03520.1 - 9.5e-22 77.2 0.5 3.8e-21 75.3 0.5 2.2 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 ORY03520.1 - 2.5e-12 45.4 39.1 0.0013 18.4 4.2 7.1 7 0 0 7 7 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 ORY03520.1 - 0.00046 20.0 1.3 0.00091 19.0 0.2 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 ORY03520.1 - 0.004 17.4 0.1 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ZapB PF06005.12 ORY03520.1 - 0.036 14.5 1.4 0.54 10.7 1.4 2.9 1 1 0 1 1 1 0 Cell division protein ZapB AAA_16 PF13191.6 ORY03520.1 - 0.094 13.1 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 ORY03520.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY03520.1 - 0.13 12.7 0.4 1 9.9 0.0 2.7 2 1 0 2 2 2 0 ABC transporter ERM PF00769.19 ORY03520.1 - 0.16 11.8 6.9 0.18 11.6 5.6 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 ORY03520.1 - 0.7 10.0 7.8 0.97 9.5 1.1 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 ORY03520.1 - 2.5 8.7 8.9 9.7 6.7 8.9 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 ORY03520.1 - 7.6 6.8 6.7 9.2 6.5 3.5 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Alg6_Alg8 PF03155.15 ORY03521.1 - 2e-162 541.5 24.0 2.4e-162 541.3 24.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PH PF00169.29 ORY03522.1 - 9.1e-10 39.0 0.4 2.3e-09 37.7 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 ORY03522.1 - 0.054 13.9 1.0 0.21 12.0 1.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain HAD_2 PF13419.6 ORY03523.1 - 5e-10 39.7 0.0 7.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY03523.1 - 4.4e-05 23.9 0.0 0.0001 22.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY03523.1 - 5.4e-05 23.2 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like F-box PF00646.33 ORY03525.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY03525.1 - 0.0003 20.6 0.5 0.00059 19.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like Peptidase_M28 PF04389.17 ORY03526.1 - 2.5e-38 131.7 0.0 3.8e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 KASH_CCD PF14662.6 ORY03528.1 - 0.12 12.2 3.1 0.14 12.0 3.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MPS2 PF17060.5 ORY03528.1 - 0.21 10.8 1.8 0.27 10.5 1.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Sde2_N_Ubi PF13019.6 ORY03529.1 - 2.2e-31 108.9 1.6 2.3e-31 108.9 0.1 1.7 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain ubiquitin PF00240.23 ORY03529.1 - 0.00098 18.8 0.4 0.0051 16.5 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family YfhD PF14151.6 ORY03529.1 - 0.045 13.9 2.8 0.045 13.9 2.8 2.4 2 1 1 3 3 3 0 YfhD-like protein RNase_J_C PF17770.1 ORY03529.1 - 0.15 13.2 0.7 0.15 13.2 0.7 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Nop PF01798.18 ORY03530.1 - 3e-80 269.0 0.1 4.4e-80 268.5 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 ORY03530.1 - 8.2e-41 139.7 0.7 1.7e-40 138.7 0.7 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain DPBB_1 PF03330.18 ORY03531.1 - 2.5e-10 40.5 0.1 4.1e-10 39.8 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY03531.1 - 3.7e-05 23.5 0.1 4.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Barwin family Clenterotox PF03505.14 ORY03531.1 - 0.076 12.6 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Clostridium enterotoxin RasGEF PF00617.19 ORY03532.1 - 7.2e-45 153.4 0.0 1.2e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY03532.1 - 1.7e-13 50.7 0.4 5.5e-13 49.1 0.4 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Cut8 PF08559.10 ORY03533.1 - 9.8e-57 192.3 0.3 1.1e-56 192.1 0.3 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein PBP1_TM PF14812.6 ORY03533.1 - 0.047 14.1 0.6 0.077 13.4 0.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCCH PF00642.24 ORY03534.1 - 8.8e-16 57.4 23.9 3.5e-11 42.7 3.9 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY03534.1 - 7.3e-10 38.4 19.3 1.1e-07 31.5 1.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY03534.1 - 3.5e-08 33.2 2.5 3.5e-08 33.2 2.5 2.8 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 ORY03534.1 - 0.00099 19.8 14.7 0.048 14.4 6.0 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 ORY03534.1 - 0.0027 18.1 0.7 0.0027 18.1 0.7 2.7 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger rRNA_proc-arch PF13234.6 ORY03535.1 - 2.6e-56 191.6 0.0 8.3e-56 189.9 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 ORY03535.1 - 1.4e-42 145.2 0.1 4.2e-42 143.6 0.0 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 ORY03535.1 - 9e-17 61.4 0.0 2.3e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY03535.1 - 2.2e-06 28.0 0.0 9.5e-06 25.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY03535.1 - 5.4e-06 26.5 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 ORY03535.1 - 0.089 12.7 0.2 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sulfatase_C PF14707.6 ORY03535.1 - 0.12 13.1 1.2 0.23 12.2 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase T2SSE PF00437.20 ORY03535.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 ORY03535.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein WD40 PF00400.32 ORY03536.1 - 2.1e-37 126.5 6.5 1.8e-09 38.1 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY03536.1 - 7.7e-19 67.8 0.0 2.1e-07 31.1 0.0 5.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 ORY03536.1 - 2.4e-13 49.5 0.0 4.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 ORY03536.1 - 3.6e-07 29.2 0.3 0.032 12.9 0.1 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY03536.1 - 1.4e-06 27.5 2.9 0.28 10.1 0.2 3.9 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY03536.1 - 0.00029 20.8 0.0 1.4 8.8 0.0 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 ORY03536.1 - 0.0018 16.7 0.1 0.61 8.3 0.0 3.6 2 1 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 ORY03536.1 - 0.0044 16.4 0.2 0.026 13.9 0.2 2.2 1 1 0 1 1 1 1 WD40-like domain PD40 PF07676.12 ORY03536.1 - 0.0048 16.8 0.0 0.46 10.5 0.0 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 ORY03536.1 - 0.01 14.8 0.3 3.2 6.6 0.0 3.1 3 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF4394 PF14339.6 ORY03536.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Leucyl-specific PF14795.6 ORY03536.1 - 0.18 11.9 0.5 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Sel1 PF08238.12 ORY03537.1 - 1.9e-38 130.0 13.0 2e-08 34.6 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat BSD PF03909.17 ORY03537.1 - 0.038 14.0 0.0 0.87 9.6 0.0 2.3 2 0 0 2 2 2 0 BSD domain HNH_repeat PF18780.1 ORY03537.1 - 0.21 11.4 0.1 0.55 10.1 0.1 1.7 1 0 0 1 1 1 0 Homing endonuclease repeat TPR_2 PF07719.17 ORY03537.1 - 2.1 8.7 8.0 4.4 7.7 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MoCF_biosynth PF00994.24 ORY03538.1 - 6.4e-67 223.7 0.2 9e-35 119.4 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 ORY03538.1 - 1.9e-37 128.5 2.1 3.8e-37 127.5 2.1 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ORY03538.1 - 9e-11 41.8 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 ORY03538.1 - 5.6 6.3 9.1 9 5.6 9.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-C2H2 PF00096.26 ORY03539.1 - 1.2e-18 66.5 16.9 1.4e-06 28.4 0.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY03539.1 - 5.4e-12 45.6 15.2 1.7e-07 31.4 0.6 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY03539.1 - 8.6e-11 41.7 16.1 7.8e-05 23.2 0.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY03539.1 - 1.3e-05 25.4 3.3 0.14 12.4 3.0 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY03539.1 - 1.5e-05 25.5 6.9 0.41 11.3 0.0 4.1 1 1 3 4 4 4 3 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORY03539.1 - 0.00019 21.6 5.2 0.31 11.2 0.4 3.4 1 1 1 3 3 3 2 Aberrant zinc-finger zf_ZIC PF18366.1 ORY03539.1 - 0.001 19.2 4.4 0.098 12.8 0.0 3.9 4 1 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 ORY03539.1 - 0.018 15.0 14.4 0.23 11.5 0.1 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.11 ORY03539.1 - 0.037 13.9 1.5 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FANCL_C PF11793.8 ORY03539.1 - 0.11 12.7 2.3 3.2 8.0 0.0 3.2 2 1 0 3 3 3 0 FANCL C-terminal domain DUF4806 PF16064.5 ORY03539.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) Ogr_Delta PF04606.12 ORY03539.1 - 0.29 11.2 3.0 1 9.4 0.1 2.7 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf_Hakai PF18408.1 ORY03539.1 - 0.39 10.5 0.0 0.39 10.5 0.0 3.1 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain zf-TRAF PF02176.18 ORY03539.1 - 0.6 10.8 9.5 1 10.1 1.5 3.6 1 1 3 4 4 4 0 TRAF-type zinc finger Zap1_zf2 PF18217.1 ORY03539.1 - 1.1 9.3 5.9 3.8 7.6 0.4 3.2 3 1 0 3 3 2 0 Zap1 zinc finger 2 zf-C2HC PF01530.18 ORY03539.1 - 1.5 9.1 5.9 6.9 7.0 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2HC type zf-C2H2_jaz PF12171.8 ORY03539.1 - 3.6 8.0 10.0 8.6 6.8 0.6 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Kinesin PF00225.23 ORY03541.1 - 2.8e-54 184.3 0.8 1.6e-36 125.9 0.1 2.0 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 ORY03541.1 - 5.6e-14 52.3 0.0 8.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding E1-E2_ATPase PF00122.20 ORY03542.1 - 5.1e-26 91.3 1.0 5.1e-26 91.3 1.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 ORY03542.1 - 4.6e-10 39.1 1.8 5.8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Borrelia_P13 PF05628.12 ORY03542.1 - 0.004 17.1 0.2 0.004 17.1 0.2 2.0 2 0 0 2 2 2 1 Borrelia membrane protein P13 RDV-p3 PF09231.10 ORY03542.1 - 0.016 13.0 0.1 0.023 12.5 0.1 1.1 1 0 0 1 1 1 0 Rice dwarf virus p3 PhoLip_ATPase_N PF16209.5 ORY03542.1 - 0.12 12.1 0.2 5.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal NAS PF03059.16 ORY03543.1 - 3.1e-70 236.7 0.1 3.8e-70 236.4 0.1 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 ORY03543.1 - 4.3e-05 23.4 0.0 7.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 ORY03544.1 - 9.7e-32 110.2 24.2 4.1e-31 108.2 13.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY03544.1 - 3.5e-19 69.0 1.2 3.5e-19 69.0 1.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 ORY03544.1 - 3.3e-10 39.1 2.4 6.7e-07 28.2 0.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORY03544.1 - 1.7e-05 23.9 0.2 0.039 12.8 0.1 3.3 2 2 1 3 3 3 2 MFS_1 like family MFS_4 PF06779.14 ORY03544.1 - 0.00025 20.5 1.2 0.00025 20.5 1.2 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ORY03544.1 - 0.00061 18.3 0.6 0.0015 17.1 0.6 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 ORY03544.1 - 2.7 8.3 6.8 13 6.1 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) OPT PF03169.15 ORY03545.1 - 1.2e-73 248.8 38.5 2.2e-72 244.6 38.5 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein CBAH PF02275.18 ORY03546.1 - 0.018 14.7 0.2 0.025 14.2 0.2 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family GMC_oxred_C PF05199.13 ORY03593.1 - 1.1e-19 71.4 0.0 1.5e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Gln_deamidase_2 PF18626.1 ORY03593.1 - 0.031 14.5 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutaminase Big_8 PF17961.1 ORY03593.1 - 0.095 12.9 0.0 0.37 11.0 0.0 1.9 1 1 1 2 2 2 0 Bacterial Ig domain Redoxin PF08534.10 ORY03594.1 - 5.3e-32 110.6 0.0 6.2e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY03594.1 - 1e-12 48.1 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 ORY03594.1 - 0.0024 18.0 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme G-gamma PF00631.22 ORY03595.1 - 6.2e-18 64.6 0.0 7.3e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain Laminin_I PF06008.14 ORY03596.1 - 0.0035 17.1 1.1 0.0047 16.7 1.1 1.1 1 0 0 1 1 1 1 Laminin Domain I DUF948 PF06103.11 ORY03596.1 - 0.0098 16.1 0.3 0.019 15.2 0.3 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 ORY03596.1 - 0.011 15.8 0.7 0.015 15.3 0.7 1.2 1 0 0 1 1 1 0 Laminin Domain II DMPK_coil PF08826.10 ORY03596.1 - 0.019 15.0 0.2 0.029 14.5 0.2 1.2 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF1664 PF07889.12 ORY03596.1 - 0.038 14.0 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 ORY03596.1 - 0.045 13.9 0.2 0.061 13.4 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 ORY03596.1 - 0.2 11.0 1.1 0.26 10.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 ORY03597.1 - 0.0035 17.1 1.1 0.0046 16.7 1.1 1.1 1 0 0 1 1 1 1 Laminin Domain I DUF948 PF06103.11 ORY03597.1 - 0.0095 16.2 0.3 0.018 15.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 ORY03597.1 - 0.011 15.8 0.5 0.016 15.2 0.5 1.1 1 0 0 1 1 1 0 Laminin Domain II DMPK_coil PF08826.10 ORY03597.1 - 0.018 15.1 0.2 0.027 14.6 0.2 1.2 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF1664 PF07889.12 ORY03597.1 - 0.037 14.1 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 ORY03597.1 - 0.045 13.9 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 ORY03597.1 - 0.18 11.1 1.0 0.24 10.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 ORY03597.1 - 0.51 10.8 2.1 1.4 9.5 2.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Alginate_lyase PF05426.12 ORY03598.1 - 7.5e-51 173.3 0.0 9.8e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase RasGEF PF00617.19 ORY03599.1 - 3.5e-62 209.7 1.4 2e-61 207.3 0.1 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORY03599.1 - 1.1e-28 99.6 0.6 3.7e-28 97.8 0.6 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 ORY03599.1 - 3.4e-16 58.6 0.1 8.8e-16 57.2 0.1 1.8 1 0 0 1 1 1 1 SH3 domain WW PF00397.26 ORY03599.1 - 5e-15 55.3 12.2 3.8e-08 33.3 0.8 2.7 2 0 0 2 2 2 2 WW domain SH3_2 PF07653.17 ORY03599.1 - 4.1e-12 45.6 0.0 2.3e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 ORY03599.1 - 3.3e-08 33.3 0.1 8.9e-08 31.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain I_LWEQ PF01608.17 ORY03599.1 - 0.92 9.7 4.9 4.5 7.5 0.3 3.0 2 1 0 3 3 3 0 I/LWEQ domain Ribosomal_S10 PF00338.22 ORY03600.1 - 5.3e-29 100.3 0.4 6.1e-29 100.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 ORY03600.1 - 0.074 13.9 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain AFG1_ATPase PF03969.16 ORY03601.1 - 6.8e-109 364.1 0.1 7e-104 347.6 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 ORY03601.1 - 5.8e-06 26.8 0.1 0.0058 17.0 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORY03601.1 - 3.1e-05 24.4 0.0 0.00045 20.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY03601.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY03601.1 - 0.00096 19.4 0.0 0.0039 17.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 ORY03601.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORY03601.1 - 0.011 15.5 0.2 0.14 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY03601.1 - 0.022 14.7 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 ORY03601.1 - 0.024 14.5 0.7 0.11 12.3 0.1 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein TniB PF05621.11 ORY03601.1 - 0.033 13.6 0.0 0.88 8.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 ORY03601.1 - 0.1 13.0 0.1 0.55 10.7 0.0 2.5 3 1 0 3 3 2 0 RNA helicase PIF1 PF05970.14 ORY03601.1 - 0.17 11.1 0.1 0.33 10.1 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase Memo PF01875.17 ORY03602.1 - 6e-77 258.4 0.0 8.5e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Mito_carr PF00153.27 ORY03603.1 - 4.8e-72 238.0 1.9 5.1e-25 87.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY03603.1 - 0.00027 20.2 0.3 0.17 11.0 0.0 3.0 3 1 0 3 3 3 2 Gammaproteobacterial serine protease FA_hydroxylase PF04116.13 ORY03604.1 - 1.1e-24 87.3 9.7 1.4e-24 86.9 8.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FRD2 PF03197.13 ORY03604.1 - 0.15 12.3 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Glutaredoxin PF00462.24 ORY03605.1 - 1.6e-18 66.6 0.0 3.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 ORY03605.1 - 4.3e-16 58.8 0.1 8.3e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY03605.1 - 8.7e-05 22.9 0.0 0.0037 17.7 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.16 ORY03605.1 - 0.00027 20.7 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 ORY03605.1 - 0.00042 20.6 0.1 0.015 15.6 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.6 ORY03605.1 - 0.00068 19.6 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 ORY03605.1 - 0.0012 18.8 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 ORY03605.1 - 0.0037 17.2 0.1 0.015 15.2 0.1 2.0 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 ORY03605.1 - 0.0091 15.7 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 Redoxin Phosducin PF02114.16 ORY03605.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 2 0 0 2 2 2 0 Phosducin SHNi-TPR PF10516.9 ORY03605.1 - 0.14 11.7 0.1 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR Alginate_lyase PF05426.12 ORY03606.1 - 6e-09 35.8 0.0 1.6e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Alginate lyase GlutR_dimer PF00745.20 ORY03606.1 - 0.037 14.5 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Nbl1_Borealin_N PF10444.9 ORY03607.1 - 3.3e-14 52.3 0.3 1e-13 50.7 0.3 1.9 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 ORY03607.1 - 0.022 14.7 0.9 0.022 14.7 0.9 2.2 2 1 0 2 2 2 0 Cell division cycle-associated protein 8 Sec23_trunk PF04811.15 ORY03608.1 - 2.2e-76 256.7 0.0 3e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY03608.1 - 4.4e-30 104.3 0.0 8.5e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORY03608.1 - 3.6e-24 84.5 0.1 6.9e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORY03608.1 - 4.8e-15 55.3 7.0 1e-14 54.3 7.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY03608.1 - 1.8e-14 53.4 0.1 4.4e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Gelsolin repeat YwiC PF14256.6 ORY03609.1 - 0.062 13.6 0.7 0.062 13.6 0.7 3.2 1 1 1 3 3 3 0 YwiC-like protein DUF4448 PF14610.6 ORY03609.1 - 0.57 9.9 3.9 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) FMN_red PF03358.15 ORY03610.1 - 2.2e-07 30.7 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 ORY03610.1 - 0.0044 17.2 0.0 0.059 13.6 0.0 2.5 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.17 ORY03610.1 - 0.0048 16.6 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold BCAS3 PF12490.8 ORY03611.1 - 3.1e-07 30.2 2.2 0.0013 18.3 1.1 2.4 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 3 WD40 PF00400.32 ORY03611.1 - 0.0091 16.8 0.4 5 8.2 0.1 3.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY03611.1 - 0.055 13.8 0.1 24 5.3 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Laminin_G_1 PF00054.23 ORY03611.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Laminin G domain RNA_pol_inhib PF16857.5 ORY03612.1 - 0.21 11.4 1.1 0.62 9.9 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase inhibitor CMAS PF02353.20 ORY03613.1 - 9.4e-45 153.0 1.3 1.3e-44 152.6 1.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 ORY03613.1 - 1.4e-15 57.4 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY03613.1 - 1.6e-14 54.4 0.0 2.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY03613.1 - 3.9e-14 53.1 0.0 6.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY03613.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY03613.1 - 4.6e-11 43.3 0.0 7.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY03613.1 - 2e-09 37.3 0.0 4.4e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY03613.1 - 6.1e-07 29.1 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 ORY03613.1 - 1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.15 ORY03613.1 - 5.5e-05 22.6 0.0 9.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G tRNA_U5-meth_tr PF05958.11 ORY03613.1 - 0.00043 19.4 0.1 0.0011 18.1 0.1 1.6 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 ORY03613.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_32 PF13679.6 ORY03613.1 - 0.0036 17.3 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORY03613.1 - 0.0041 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 ORY03613.1 - 0.0041 16.9 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ORY03613.1 - 0.0044 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ORY03613.1 - 0.008 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ORY03613.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 ORY03613.1 - 0.046 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 ORY03613.1 - 0.16 11.2 0.0 0.37 10.0 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain TANGO2 PF05742.12 ORY03614.1 - 7.7e-65 219.4 0.0 8.7e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 SMI1_KNR4 PF09346.10 ORY03615.1 - 0.00086 19.7 0.0 0.0015 19.0 0.0 1.5 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ORY03615.1 - 0.0021 18.5 0.0 0.005 17.3 0.0 1.6 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 ORY03615.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall STE PF02200.16 ORY03616.1 - 0.083 13.3 0.4 0.17 12.3 0.4 1.5 1 1 0 1 1 1 0 STE like transcription factor zf-C2H2_jaz PF12171.8 ORY03617.1 - 1.2e-07 31.8 0.6 2.1e-07 31.0 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY03617.1 - 2.5e-07 30.9 0.6 4.1e-07 30.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 ORY03617.1 - 3.4e-05 23.5 0.5 5.7e-05 22.8 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger zf_C2H2_ZHX PF18387.1 ORY03617.1 - 0.0028 17.2 0.1 0.0059 16.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain SNRNP27 PF08648.12 ORY03617.1 - 0.0085 16.1 0.6 0.0085 16.1 0.6 2.6 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 ORY03617.1 - 0.011 15.9 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 0 DBF zinc finger UNC-79 PF14776.6 ORY03617.1 - 0.012 14.4 3.2 0.017 13.9 3.2 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Pinin_SDK_memA PF04696.13 ORY03617.1 - 0.85 9.7 27.5 0.12 12.4 12.8 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region CDC37_N PF03234.14 ORY03617.1 - 0.99 10.3 13.2 9 7.2 0.4 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF4355 PF14265.6 ORY03617.1 - 2.3 8.5 24.7 0.41 10.9 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) MRP_L53 PF10780.9 ORY03618.1 - 4.7e-17 61.9 1.0 9.7e-17 60.9 0.6 1.7 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 YjeJ PF15922.5 ORY03618.1 - 0.00053 19.3 0.1 0.0006 19.1 0.1 1.0 1 0 0 1 1 1 1 YjeJ-like MAGE PF01454.19 ORY03619.1 - 1.6e-48 165.3 0.1 2.6e-48 164.5 0.1 1.3 1 0 0 1 1 1 1 MAGE family GTP_EFTU PF00009.27 ORY03620.1 - 4.2e-53 179.8 0.0 6.9e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY03620.1 - 3.8e-40 136.7 0.0 8.1e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY03620.1 - 6.3e-11 42.5 1.3 1.8e-10 41.0 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY03620.1 - 3.3e-09 36.8 0.2 1.5e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SRPRB PF09439.10 ORY03620.1 - 0.00016 21.2 0.6 0.0042 16.5 0.6 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY03620.1 - 0.021 14.4 0.3 0.061 12.9 0.0 1.8 2 0 0 2 2 2 0 Ras family FlpD PF02662.16 ORY03620.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 ORY03620.1 - 0.092 12.7 2.1 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 G-alpha PF00503.20 ORY03620.1 - 0.13 11.4 0.0 0.42 9.7 0.1 1.8 2 1 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 ORY03620.1 - 0.15 11.6 0.4 0.77 9.3 0.1 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B EloA-BP1 PF15870.5 ORY03621.1 - 2e-07 31.4 0.4 0.0079 16.5 0.1 2.4 1 1 1 2 2 2 2 ElonginA binding-protein 1 Opy2 PF09463.10 ORY03621.1 - 1 9.7 5.7 0.91 9.9 0.2 2.9 3 0 0 3 3 3 0 Opy2 protein UCH PF00443.29 ORY03622.1 - 2.9e-51 174.4 0.0 3.9e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY03622.1 - 2.3e-24 86.6 0.9 2.3e-24 86.6 0.9 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY03622.1 - 2e-12 47.2 11.1 2e-12 47.2 11.1 3.0 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.6 ORY03622.1 - 0.21 11.0 6.1 8.7 5.9 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain Mut7-C PF01927.16 ORY03622.1 - 0.29 11.2 3.1 9.3 6.3 0.2 2.6 2 0 0 2 2 2 0 Mut7-C RNAse domain HalOD2 PF18547.1 ORY03622.1 - 0.3 11.0 6.5 4.1 7.4 0.0 3.7 3 0 0 3 3 3 0 Halobacterial output domain 2 zinc_ribbon_4 PF13717.6 ORY03622.1 - 0.36 10.8 5.3 8.3 6.4 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 ORY03622.1 - 0.55 9.9 7.2 3.1 7.5 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Ribosomal_L13 PF00572.18 ORY03623.1 - 1e-10 41.9 0.1 8.7e-09 35.7 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 TFIID_30kDa PF03540.13 ORY03624.1 - 1.8e-26 91.8 0.2 2.8e-26 91.2 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Tim54 PF11711.8 ORY03624.1 - 0.016 14.0 2.2 0.018 13.8 2.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Bromo_TP PF07524.13 ORY03624.1 - 0.056 13.5 0.1 0.49 10.4 0.1 2.2 1 1 0 1 1 1 0 Bromodomain associated PBP1_TM PF14812.6 ORY03624.1 - 0.059 13.8 4.4 0.1 13.0 4.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TAF4 PF05236.14 ORY03624.1 - 0.26 11.0 10.4 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.14 ORY03624.1 - 0.27 9.5 2.6 0.26 9.5 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 ORY03624.1 - 0.33 11.4 3.3 0.43 11.0 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 ORY03624.1 - 1.9 7.2 3.7 2.3 6.9 3.7 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 ORY03624.1 - 2.6 7.8 9.7 3.6 7.3 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 ORY03624.1 - 4.4 7.0 12.7 7.5 6.3 12.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3464 PF11947.8 ORY03624.1 - 8.1 6.2 7.1 14 5.4 7.1 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 APG5 PF04106.12 ORY03625.1 - 6.9e-63 212.3 0.2 1.4e-62 211.3 0.1 1.5 2 0 0 2 2 2 1 Autophagy protein Apg5 OTU PF02338.19 ORY03625.1 - 0.066 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease Nnf1 PF03980.14 ORY03626.1 - 5e-19 68.7 10.3 7.6e-19 68.1 8.4 2.0 2 0 0 2 2 2 1 Nnf1 HrpB7 PF09486.10 ORY03626.1 - 0.017 15.5 0.8 0.017 15.5 0.8 2.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) TPD52 PF04201.15 ORY03626.1 - 0.025 14.2 10.8 0.26 10.9 5.7 2.4 1 1 0 2 2 2 0 Tumour protein D52 family Med30 PF11315.8 ORY03626.1 - 0.093 12.9 11.1 1.8 8.8 11.1 2.1 1 1 0 1 1 1 0 Mediator complex subunit 30 Nsp1_C PF05064.13 ORY03626.1 - 0.31 10.8 8.2 0.38 10.6 6.2 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region Mod_r PF07200.13 ORY03626.1 - 0.38 10.9 14.5 2.6 8.2 1.8 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 ORY03626.1 - 0.41 11.1 14.9 0.042 14.3 7.4 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 ORY03626.1 - 0.51 10.4 12.1 2.5 8.1 6.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 ORY03626.1 - 1.2 9.6 10.7 3.4 8.1 5.7 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain PhoU PF01895.19 ORY03626.1 - 1.2 9.6 5.9 1.7 9.2 1.1 2.6 1 1 1 2 2 2 0 PhoU domain DUF1993 PF09351.10 ORY03626.1 - 1.4 9.1 7.1 2.2 8.4 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) MutS_III PF05192.18 ORY03626.1 - 2 8.6 4.8 2.7 8.2 4.8 1.3 1 0 0 1 1 1 0 MutS domain III Peptidase_S46 PF10459.9 ORY03626.1 - 2.5 6.6 9.4 0.27 9.8 2.2 1.9 1 1 1 2 2 2 0 Peptidase S46 FAM76 PF16046.5 ORY03626.1 - 2.8 7.2 9.0 3.5 6.9 9.0 1.2 1 0 0 1 1 1 0 FAM76 protein DUF2203 PF09969.9 ORY03626.1 - 6 7.6 8.0 7 7.4 3.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TSNAXIP1_N PF15739.5 ORY03626.1 - 7.2 7.0 11.6 3.7 8.0 3.3 2.5 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus TSC22 PF01166.18 ORY03626.1 - 7.3 7.0 11.3 15 6.0 0.3 3.4 3 2 0 3 3 3 0 TSC-22/dip/bun family adh_short_C2 PF13561.6 ORY03627.1 - 1.4e-10 41.1 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY03627.1 - 6.6e-09 35.5 0.1 2.1e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ORY03627.1 - 9.2e-07 28.6 0.0 2.1e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GTP_cyclohydroI PF01227.22 ORY03628.1 - 4.4e-78 260.8 0.3 5.2e-78 260.6 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ORY03628.1 - 0.00065 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 ORY03628.1 - 0.024 14.0 0.1 0.057 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) AFT PF08731.11 ORY03628.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor AFT Ribosomal_L10 PF00466.20 ORY03629.1 - 1.1e-10 41.5 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 NPV_P10 PF05531.12 ORY03629.1 - 0.04 14.4 0.7 0.076 13.5 0.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MbeB_N PF04837.12 ORY03629.1 - 0.19 12.1 0.9 0.6 10.5 0.1 2.2 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Bmt2 PF11968.8 ORY03630.1 - 4.6e-70 235.9 0.0 5.7e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_8 PF05148.15 ORY03630.1 - 1.9e-05 24.6 0.0 3.9e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Hypothetical methyltransferase Orthopox_A47 PF06334.11 ORY03630.1 - 0.035 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A47 protein MethyTransf_Reg PF10119.9 ORY03630.1 - 0.22 12.3 0.7 0.49 11.2 0.7 1.6 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain LRR_4 PF12799.7 ORY03631.1 - 0.0014 19.0 8.8 14 6.3 0.1 6.4 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 ORY03631.1 - 0.0049 17.5 0.1 0.038 14.7 0.1 2.7 1 0 0 1 1 1 1 Leucine Rich Repeat LRR_1 PF00560.33 ORY03631.1 - 0.57 10.9 5.8 27 5.9 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat bZIP_1 PF00170.21 ORY03632.1 - 1e-09 38.4 8.4 1.9e-09 37.5 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 ORY03632.1 - 3.9e-07 30.4 2.9 3.9e-07 30.4 2.9 2.6 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 ORY03632.1 - 6.1e-07 29.7 1.1 6.1e-07 29.7 1.1 3.8 3 2 1 4 4 4 1 Aft1 HRA domain bZIP_2 PF07716.15 ORY03632.1 - 2.5e-06 27.4 10.4 4.8e-06 26.5 10.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper THOC7 PF05615.13 ORY03632.1 - 0.0035 17.6 2.1 0.0059 16.9 2.1 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 bZIP_Maf PF03131.17 ORY03632.1 - 0.0035 17.8 7.1 0.0071 16.8 7.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Peptidase_C12 PF01088.21 ORY03633.1 - 4.8e-73 245.4 0.1 9.3e-73 244.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ORY03633.1 - 3.7e-17 62.0 3.8 8.9e-17 60.7 3.8 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases UPF0242 PF06785.11 ORY03633.1 - 0.0048 17.0 2.6 0.0073 16.4 2.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4061 PF13270.6 ORY03633.1 - 0.011 16.0 2.6 0.023 15.0 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) ACCA PF03255.14 ORY03633.1 - 0.012 15.5 1.2 0.02 14.8 1.2 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4164 PF13747.6 ORY03633.1 - 0.024 14.9 3.4 0.048 14.0 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CCDC-167 PF15188.6 ORY03633.1 - 0.08 13.3 1.8 0.15 12.4 1.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 BBS2_C PF14782.6 ORY03633.1 - 0.17 10.6 2.3 0.24 10.1 2.3 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PRP21_like_P PF12230.8 ORY03634.1 - 4.5e-54 183.6 5.6 7.4e-54 182.9 5.6 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 ORY03634.1 - 1.5e-19 69.7 1.5 3.8e-19 68.4 1.5 1.7 1 0 0 1 1 1 1 Surp module ubiquitin PF00240.23 ORY03634.1 - 8.9e-06 25.4 0.0 5e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 ORY03634.1 - 3.4e-05 23.3 0.2 7.2e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Drf_FH1 PF06346.12 ORY03634.1 - 0.0039 16.9 42.0 0.012 15.4 42.0 1.8 1 0 0 1 1 1 1 Formin Homology Region 1 Ubiquitin_2 PF14560.6 ORY03634.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain PQQ_2 PF13360.6 ORY03635.1 - 3.5e-18 66.1 0.0 6.8e-10 38.9 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 ORY03635.1 - 4.5e-15 54.8 0.2 0.00063 19.6 0.0 4.1 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 ORY03635.1 - 3.2e-05 24.3 3.2 0.94 10.1 0.0 5.2 5 1 0 5 5 5 2 PQQ-like domain Sema PF01403.19 ORY03635.1 - 0.16 10.8 0.0 0.41 9.4 0.0 1.6 2 0 0 2 2 2 0 Sema domain GATA PF00320.27 ORY03636.1 - 1.1e-28 98.5 20.6 2.1e-16 59.2 2.8 2.2 2 0 0 2 2 2 2 GATA zinc finger ArfGap PF01412.18 ORY03636.1 - 1.3e-05 25.2 10.1 0.0039 17.2 0.5 2.1 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf DZR PF12773.7 ORY03636.1 - 0.005 16.8 15.4 0.14 12.2 4.6 3.1 1 1 2 3 3 3 1 Double zinc ribbon Auto_anti-p27 PF06677.12 ORY03636.1 - 0.018 15.2 0.5 0.018 15.2 0.5 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 ORY03636.1 - 0.022 14.3 0.1 0.022 14.3 0.1 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding zf-B_box PF00643.24 ORY03636.1 - 0.023 14.8 14.3 0.41 10.8 3.9 3.0 2 1 0 2 2 2 0 B-box zinc finger eIF-5_eIF-2B PF01873.17 ORY03636.1 - 0.2 11.5 0.4 0.2 11.5 0.4 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-piccolo PF05715.13 ORY03636.1 - 0.27 11.4 19.2 0.65 10.2 0.9 4.0 1 1 2 3 3 3 0 Piccolo Zn-finger zf-ribbon_3 PF13248.6 ORY03636.1 - 1.4 8.4 18.3 1.3 8.5 0.5 4.2 4 0 0 4 4 4 0 zinc-ribbon domain HIPIP PF01355.17 ORY03636.1 - 2.5 8.5 19.0 12 6.3 0.7 4.0 1 1 3 4 4 4 0 High potential iron-sulfur protein A2L_zn_ribbon PF08792.10 ORY03636.1 - 4.6 7.1 13.1 16 5.4 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 ORY03636.1 - 7.8 6.7 13.7 0.31 11.2 0.6 3.0 2 1 1 3 3 3 0 Zinc ribbon domain C2 PF00168.30 ORY03638.1 - 4e-12 46.3 0.0 5.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 C2 domain OxoGdeHyase_C PF16870.5 ORY03639.1 - 4.1e-47 159.7 0.0 7.8e-47 158.8 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 ORY03639.1 - 1.8e-45 154.8 0.0 2.8e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORY03639.1 - 1.1e-39 136.2 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ABC_membrane PF00664.23 ORY03697.1 - 2.8e-131 437.1 29.4 1.4e-69 234.8 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY03697.1 - 4.5e-64 215.1 0.2 1.7e-35 122.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY03697.1 - 3.8e-16 59.2 7.4 4.9e-07 29.4 2.1 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY03697.1 - 2.9e-07 30.1 0.4 0.027 14.2 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY03697.1 - 8.6e-07 29.3 0.4 0.11 12.8 0.1 3.8 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 ORY03697.1 - 1.3e-06 27.5 2.0 0.001 18.0 0.3 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ORY03697.1 - 3.6e-06 27.0 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY03697.1 - 5.7e-06 26.8 7.0 0.05 14.0 1.9 3.8 2 2 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 ORY03697.1 - 2.3e-05 24.6 0.0 0.17 11.9 0.0 2.8 2 0 0 2 2 2 2 Helicase HerA, central domain Zeta_toxin PF06414.12 ORY03697.1 - 2.3e-05 23.7 0.4 0.02 14.2 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin G-alpha PF00503.20 ORY03697.1 - 4e-05 22.9 0.0 0.24 10.5 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit PRK PF00485.18 ORY03697.1 - 5.6e-05 23.0 0.0 0.061 13.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 ORY03697.1 - 6.4e-05 22.8 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ORY03697.1 - 7.8e-05 22.5 0.7 1.6 8.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 ORY03697.1 - 0.00015 21.3 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORY03697.1 - 0.00019 20.9 0.1 0.85 8.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF815 PF05673.13 ORY03697.1 - 0.0002 20.6 0.1 0.33 10.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY03697.1 - 0.00021 21.9 0.0 0.27 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY03697.1 - 0.00032 20.5 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY03697.1 - 0.0007 19.8 5.9 0.88 9.8 0.6 4.5 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 ORY03697.1 - 0.00088 19.1 0.2 1.8 8.3 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_5 PF07728.14 ORY03697.1 - 0.0013 18.8 0.0 2.8 8.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORY03697.1 - 0.0013 18.9 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 ORY03697.1 - 0.0038 17.1 0.1 2 8.3 0.0 3.1 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 ORY03697.1 - 0.013 15.8 0.2 10 6.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 ORY03697.1 - 0.014 15.3 0.0 0.9 9.4 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_21 PF13304.6 ORY03697.1 - 0.018 14.8 0.2 8.4 6.1 0.0 3.4 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 ORY03697.1 - 0.021 14.8 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF4951 PF16309.5 ORY03697.1 - 0.027 14.5 0.2 1.8 8.6 0.0 3.3 4 0 0 4 4 2 0 Domian of unknown function (DUF4951) AAA_25 PF13481.6 ORY03697.1 - 0.031 13.9 0.2 12 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ORY03697.1 - 0.042 13.9 0.1 14 5.8 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORY03697.1 - 0.046 13.5 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 ORY03697.1 - 0.062 13.2 0.1 13 5.7 0.1 2.8 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 ORY03697.1 - 0.072 13.3 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FumaraseC_C PF10415.9 ORY03697.1 - 0.086 13.3 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Fumarase C C-terminus RNA_helicase PF00910.22 ORY03697.1 - 0.14 12.6 0.0 30 5.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dala_Dala_lig_N PF01820.21 ORY03697.1 - 0.15 12.5 0.0 8.8 6.9 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus NDUF_B12 PF08122.12 ORY03697.1 - 1.8 8.7 3.2 66 3.7 0.1 3.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family ABC_membrane PF00664.23 ORY03698.1 - 6.8e-120 399.8 32.8 1.7e-61 208.3 13.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY03698.1 - 5.6e-65 218.0 0.1 5e-36 124.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY03698.1 - 5.3e-14 52.2 10.9 8.3e-06 25.4 3.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY03698.1 - 3e-07 30.1 0.2 0.022 14.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORY03698.1 - 1.6e-06 27.2 3.5 0.0012 17.7 0.3 2.6 3 0 0 3 3 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORY03698.1 - 2e-06 28.1 0.8 0.082 13.2 0.1 3.7 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY03698.1 - 3.1e-06 27.2 0.2 0.12 12.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 ORY03698.1 - 8e-06 25.3 0.7 0.0098 15.2 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_30 PF13604.6 ORY03698.1 - 2e-05 24.4 0.4 0.77 9.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 ORY03698.1 - 2.5e-05 23.6 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.6 ORY03698.1 - 2.8e-05 24.0 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 ORY03698.1 - 4.6e-05 23.9 7.9 0.077 13.4 2.5 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 ORY03698.1 - 6.8e-05 22.5 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 ORY03698.1 - 0.00015 21.9 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain DEAD PF00270.29 ORY03698.1 - 0.00016 21.5 0.1 0.85 9.4 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase SbcCD_C PF13558.6 ORY03698.1 - 0.00026 21.1 3.6 0.85 9.9 0.6 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 ORY03698.1 - 0.00031 20.0 0.0 0.54 9.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY03698.1 - 0.00062 20.3 0.1 0.8 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY03698.1 - 0.00092 18.6 0.3 0.78 9.0 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_24 PF13479.6 ORY03698.1 - 0.00093 19.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORY03698.1 - 0.0011 19.0 0.1 0.82 9.8 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 ORY03698.1 - 0.0013 18.7 0.1 2.1 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Roc PF08477.13 ORY03698.1 - 0.0014 18.8 0.1 0.36 11.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 ORY03698.1 - 0.0023 18.1 0.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORY03698.1 - 0.0024 17.8 0.2 5.9 6.6 0.0 3.5 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 ORY03698.1 - 0.0049 16.6 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 ORY03698.1 - 0.011 15.3 0.1 16 5.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 ORY03698.1 - 0.012 15.9 0.4 2 8.7 0.1 3.3 3 1 0 3 3 2 0 AAA domain APS_kinase PF01583.20 ORY03698.1 - 0.031 14.2 0.1 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF4951 PF16309.5 ORY03698.1 - 0.039 14.0 0.1 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) AAA_28 PF13521.6 ORY03698.1 - 0.057 13.7 0.4 12 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY03698.1 - 0.088 12.7 0.1 21 5.0 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 ORY03698.1 - 0.089 12.7 0.0 6 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 ORY03698.1 - 0.089 12.7 0.0 20 5.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3937 PF13073.6 ORY03698.1 - 0.1 12.8 0.1 0.42 10.8 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) RNA_helicase PF00910.22 ORY03698.1 - 0.1 13.0 0.0 40 4.6 0.0 3.1 3 0 0 3 3 3 0 RNA helicase IstB_IS21 PF01695.17 ORY03698.1 - 0.12 12.1 1.6 38 3.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 ORY03698.1 - 0.13 11.4 0.2 7.3 5.7 0.2 2.6 2 1 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 ORY03698.1 - 0.14 11.9 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 ORY03698.1 - 0.16 12.0 0.8 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Dynamin family zf-C2H2 PF00096.26 ORY03699.1 - 9.8e-17 60.4 9.0 1.4e-08 34.7 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03699.1 - 1.3e-10 41.2 7.9 8.4e-05 23.1 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY03699.1 - 2.4e-08 34.0 16.0 2.7e-07 30.7 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY03699.1 - 8.3e-06 26.0 1.1 0.056 13.7 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY03699.1 - 8.6e-06 26.3 0.6 0.011 16.3 0.1 2.0 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORY03699.1 - 0.00014 22.1 2.1 0.00017 21.8 2.1 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-met PF12874.7 ORY03699.1 - 0.00035 20.8 0.8 0.83 10.1 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 ORY03699.1 - 0.00056 19.9 2.1 0.026 14.5 0.7 2.1 2 0 0 2 2 2 1 BED zinc finger zf-LYAR PF08790.11 ORY03699.1 - 0.001 18.9 0.5 0.92 9.5 0.0 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-TRAF PF02176.18 ORY03699.1 - 0.024 15.3 2.0 0.1 13.3 1.9 1.8 1 1 0 1 1 1 0 TRAF-type zinc finger IBR PF01485.21 ORY03699.1 - 0.026 14.8 1.1 0.88 9.8 1.1 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Ogr_Delta PF04606.12 ORY03699.1 - 0.048 13.6 0.5 5.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 ORY03699.1 - 0.065 13.3 0.1 0.065 13.3 0.1 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY03699.1 - 0.077 13.3 3.7 0.12 12.7 3.7 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.12 ORY03699.1 - 0.99 7.9 3.6 5.2 5.5 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.6 ORY03699.1 - 1.1 9.1 19.8 1.1 9.0 2.5 3.2 3 1 0 3 3 3 0 C2H2-type zinc-finger domain RRM_2 PF04059.12 ORY03700.1 - 6.2e-46 154.5 0.6 7.9e-46 154.2 0.6 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ORY03700.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 ORY03700.1 - 0.069 13.2 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family BRAP2 PF07576.12 ORY03700.1 - 0.078 13.2 0.3 0.11 12.7 0.3 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 A_deaminase PF00962.22 ORY03702.1 - 1.1e-36 126.8 0.0 1.3e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Uricase PF01014.18 ORY03703.1 - 1.6e-62 209.5 4.3 1.3e-35 122.5 1.2 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY03703.1 - 0.045 14.3 0.4 0.11 13.1 0.1 1.8 2 0 0 2 2 2 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY03704.1 - 1.7e-59 199.8 2.0 2.1e-34 118.6 1.1 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY03704.1 - 0.018 15.6 0.3 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 Dihydroneopterin aldolase PALP PF00291.25 ORY03705.1 - 1.9e-74 250.7 0.1 2.3e-74 250.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RELT PF12606.8 ORY03705.1 - 0.17 10.9 0.0 0.39 9.8 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 polyprenyl_synt PF00348.17 ORY03706.1 - 3.1e-94 314.8 0.0 3.9e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase AAA_35 PF14516.6 ORY03706.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Birna_VP2 PF01766.17 ORY03706.1 - 0.061 12.3 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Birnavirus VP2 protein ATP-synt_E PF05680.12 ORY03707.1 - 4.6e-24 84.6 0.2 5.1e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.12 ORY03707.1 - 0.14 12.5 4.7 0.17 12.2 4.7 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) zf-C2H2 PF00096.26 ORY03708.1 - 7.1e-15 54.5 7.9 1.5e-07 31.5 1.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY03708.1 - 3.7e-10 39.8 6.9 0.0002 21.9 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY03708.1 - 8e-08 32.4 14.8 4.1e-07 30.1 2.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain FOXP-CC PF16159.5 ORY03708.1 - 1.6e-05 25.5 0.8 0.078 13.6 0.1 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-met PF12874.7 ORY03708.1 - 0.00012 22.3 1.9 0.054 13.9 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY03708.1 - 0.00016 21.9 3.2 0.19 12.1 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY03708.1 - 0.00044 20.4 2.8 0.0014 18.8 2.9 1.6 1 1 0 1 1 1 1 Aberrant zinc-finger zf-BED PF02892.15 ORY03708.1 - 0.0028 17.7 3.8 0.058 13.4 0.3 2.3 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_8 PF15909.5 ORY03708.1 - 0.0064 16.8 1.6 0.03 14.6 1.6 1.8 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-LYAR PF08790.11 ORY03708.1 - 0.0072 16.2 0.3 2.8 7.9 0.1 2.4 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORY03708.1 - 0.034 14.5 2.1 0.28 11.5 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 ORY03708.1 - 0.12 12.6 3.5 0.29 11.4 3.7 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORY03708.1 - 0.26 11.3 0.4 0.26 11.3 0.4 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger G_glu_transpept PF01019.21 ORY03709.1 - 9.9e-130 433.7 0.0 1.2e-129 433.4 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Polysacc_deac_1 PF01522.21 ORY03710.1 - 6.2e-34 116.6 0.0 9.3e-34 116.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY03710.1 - 0.001 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Baculo_PEP_C PF04513.12 ORY03711.1 - 0.014 15.5 0.4 0.021 14.8 0.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 ORY03711.1 - 0.12 12.1 11.7 0.099 12.4 10.6 1.5 1 1 0 1 1 1 0 Bacterial collagen, middle region GREB1 PF15782.5 ORY03711.1 - 9.8 3.1 10.9 10 3.1 10.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NDUF_B8 PF05821.11 ORY03712.1 - 6.9e-07 29.3 1.9 2.2e-06 27.6 1.9 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) RCR PF12273.8 ORY03713.1 - 0.0048 17.5 2.9 0.014 16.0 1.9 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1179 PF06678.11 ORY03713.1 - 0.008 16.2 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1179) EphA2_TM PF14575.6 ORY03713.1 - 0.1 13.5 0.0 0.14 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 ORY03713.1 - 0.1 13.0 0.1 0.15 12.4 0.1 1.4 1 1 0 1 1 1 0 Commissureless Amidohydro_1 PF01979.20 ORY03716.1 - 2.9e-78 263.6 0.6 3.4e-78 263.4 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY03716.1 - 2.9e-24 86.4 0.4 6.9e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ORY03716.1 - 0.014 14.7 0.0 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 ORY03717.1 - 2.6e-78 263.8 0.7 3e-78 263.5 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY03717.1 - 2.5e-24 86.6 0.3 6.3e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ORY03717.1 - 0.011 15.1 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 Adenosine/AMP deaminase GDI PF00996.18 ORY03718.1 - 6.6e-233 772.9 0.2 7.8e-233 772.7 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 ORY03718.1 - 0.087 12.9 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Dda helicase SH3 domain MatE PF01554.18 ORY03719.1 - 1.2e-41 142.0 25.1 6.3e-22 77.9 9.0 2.3 2 0 0 2 2 2 2 MatE DUF3566 PF12089.8 ORY03719.1 - 0.021 15.2 4.2 0.021 15.2 4.2 2.5 2 1 1 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Polysacc_synt_C PF14667.6 ORY03719.1 - 0.096 12.8 0.1 0.096 12.8 0.1 4.1 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain DUF373 PF04123.13 ORY03719.1 - 0.21 11.0 13.2 0.04 13.4 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF3302 PF11742.8 ORY03719.1 - 3.1 8.0 8.1 1.7 8.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3302) FMN_red PF03358.15 ORY03721.1 - 5.5e-08 32.7 0.0 8.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase CsbD PF05532.12 ORY03722.1 - 2.5e-11 43.3 6.2 1.7e-05 24.7 0.6 2.3 2 0 0 2 2 2 2 CsbD-like Cluap1 PF10234.9 ORY03723.1 - 0.0086 15.5 9.4 0.013 14.9 9.4 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 KASH_CCD PF14662.6 ORY03723.1 - 0.032 14.1 13.7 0.045 13.6 13.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SOGA PF11365.8 ORY03723.1 - 0.08 14.1 10.1 3.8 8.7 5.7 2.8 2 1 0 2 2 2 0 Protein SOGA TMF_DNA_bd PF12329.8 ORY03723.1 - 0.18 11.8 10.4 0.12 12.4 1.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 ORY03723.1 - 0.19 11.1 6.9 0.27 10.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 ORY03723.1 - 0.53 10.4 13.8 0.096 12.8 4.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 ORY03723.1 - 0.55 9.5 2.8 0.77 9.1 2.8 1.2 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 ORY03723.1 - 0.73 9.6 6.8 1.1 9.0 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 ORY03723.1 - 1 9.2 12.5 3.1 7.6 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF1515 PF07439.11 ORY03723.1 - 1.3 9.1 4.6 0.43 10.6 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 ORY03723.1 - 1.8 8.6 13.4 5.3 7.1 13.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 ORY03723.1 - 3.6 7.1 7.6 4.9 6.6 7.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 ORY03723.1 - 8.5 7.1 9.4 1.4 9.6 3.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA AbrB PF05145.12 ORY03724.1 - 0.09 11.7 0.0 0.093 11.7 0.0 1.0 1 0 0 1 1 1 0 Transition state regulatory protein AbrB PGM_PMM_I PF02878.16 ORY03725.1 - 9.8e-37 125.7 0.2 1.7e-36 125.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORY03725.1 - 2.6e-29 101.7 0.0 4.8e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORY03725.1 - 6.1e-17 62.1 0.1 1.8e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORY03725.1 - 2.4e-06 27.6 0.0 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arginase PF00491.21 ORY03725.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Arginase family IBN_N PF03810.19 ORY03726.1 - 2.9e-05 23.9 0.0 0.00013 21.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 ORY03726.1 - 0.00032 20.0 1.3 0.00032 20.0 1.3 2.6 2 0 0 2 2 2 1 CRM1 C terminal Importin_rep_6 PF18829.1 ORY03726.1 - 0.0096 16.0 1.7 1 9.5 0.0 3.5 3 0 0 3 3 3 1 Importin repeat 6 Xpo1 PF08389.12 ORY03726.1 - 0.072 13.2 6.7 0.75 9.8 0.0 5.0 6 0 0 6 6 6 0 Exportin 1-like protein DUF1836 PF08876.11 ORY03726.1 - 0.11 12.6 0.3 0.62 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) Prophage_tail PF06605.11 ORY03727.1 - 0.041 13.1 0.9 0.084 12.1 0.1 1.7 2 0 0 2 2 2 0 Prophage endopeptidase tail DUF3716 PF12511.8 ORY03727.1 - 0.082 13.0 1.1 0.16 12.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Isochorismatase PF00857.20 ORY03763.1 - 1.7e-20 73.9 0.0 3.3e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 ORY03764.1 - 4e-50 170.7 45.6 4e-50 170.7 45.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY03764.1 - 2.3e-15 56.1 25.1 3.4e-15 55.5 25.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY03764.1 - 4.2e-15 55.6 6.6 4.2e-15 55.6 6.6 3.8 3 1 0 3 3 3 1 Sugar (and other) transporter Transp_inhibit PF18791.1 ORY03764.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain ATP-synt_Z PF16594.5 ORY03764.1 - 1.5 8.4 11.8 1.5 8.3 0.1 3.8 3 1 1 4 4 4 0 Putative AtpZ or ATP-synthase-associated Isochorismatase PF00857.20 ORY03765.1 - 3.5e-18 66.4 0.0 5.7e-18 65.7 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family FAD_binding_4 PF01565.23 ORY03766.1 - 8.6e-17 61.2 1.4 1.5e-14 53.9 1.4 2.5 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY03766.1 - 5.4e-16 58.4 2.9 5.4e-16 58.4 2.9 2.1 3 0 0 3 3 3 1 Berberine and berberine like DUF4858 PF16150.5 ORY03766.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) Isochorismatase PF00857.20 ORY03767.1 - 1.2e-19 71.1 0.0 2.4e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family FAD_binding_4 PF01565.23 ORY03768.1 - 2.6e-24 85.5 0.4 4.9e-24 84.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY03768.1 - 3e-14 52.8 2.0 3e-14 52.8 2.0 2.1 3 0 0 3 3 3 1 Berberine and berberine like DUF4858 PF16150.5 ORY03768.1 - 0.092 12.8 0.4 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4858) PX PF00787.24 ORY03769.1 - 1.9e-14 53.6 0.0 4.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 PX domain Hormone_1 PF00103.20 ORY03769.1 - 0.011 15.5 0.3 0.018 14.8 0.3 1.3 1 0 0 1 1 1 0 Somatotropin hormone family DUF1967 PF09269.11 ORY03769.1 - 0.044 13.7 1.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) DUF2884 PF11101.8 ORY03769.1 - 0.2 11.1 7.8 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) DUF4559 PF15112.6 ORY03769.1 - 8.4 6.0 10.8 1.6 8.4 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) CBM_14 PF01607.24 ORY03770.1 - 0.62 10.3 5.2 1.4 9.1 5.2 1.5 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain TetR_C_20 PF17925.1 ORY03770.1 - 2.2 8.6 6.2 7.8 6.9 0.1 3.5 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NKAIN PF05640.14 ORY03772.1 - 0.00082 18.7 10.3 0.0018 17.5 10.3 1.8 1 1 0 1 1 1 1 Na,K-Atpase Interacting protein NDK PF00334.19 ORY03773.1 - 8.2e-53 178.0 0.0 1.1e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CBM_21 PF03370.13 ORY03774.1 - 1.2e-29 102.7 0.8 2.3e-29 101.8 0.8 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY03774.1 - 1.4e-11 44.8 1.5 3.7e-11 43.5 1.5 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Metallophos PF00149.28 ORY03775.1 - 7.8e-17 62.4 1.7 2.4e-16 60.9 1.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY03775.1 - 6.8e-09 36.1 0.0 9.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_C PF14008.6 ORY03775.1 - 0.0027 18.5 0.3 0.0095 16.8 0.3 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Agglutinin PF07468.11 ORY03775.1 - 0.066 13.4 0.5 0.26 11.5 0.5 1.9 1 1 0 1 1 1 0 Agglutinin domain Josephin PF02099.17 ORY03775.1 - 0.92 9.6 5.2 0.33 11.0 0.2 2.3 3 0 0 3 3 3 0 Josephin RRM_1 PF00076.22 ORY03776.1 - 4.7e-67 221.7 10.3 1.1e-19 70.0 0.0 8.1 8 0 0 8 8 8 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY03776.1 - 6e-07 29.4 0.5 0.26 11.3 0.0 4.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY03776.1 - 2e-06 27.8 0.3 3 8.0 0.0 5.2 6 0 0 6 6 6 3 RNA recognition motif RRM_3 PF08777.11 ORY03776.1 - 7.1e-06 26.0 25.1 0.012 15.7 1.0 6.0 4 2 1 5 5 5 3 RNA binding motif SDA1 PF05285.12 ORY03776.1 - 1.6e-05 24.5 26.5 1.6e-05 24.5 26.5 3.2 3 1 0 3 3 3 1 SDA1 SET_assoc PF11767.8 ORY03776.1 - 0.0054 16.3 0.5 5.2 6.8 0.2 3.5 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated GFO_IDH_MocA PF01408.22 ORY03777.1 - 1e-19 71.5 0.0 1.7e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY03777.1 - 1.6e-07 31.3 0.0 5e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain tRNA_NucTran2_2 PF13735.6 ORY03778.1 - 0.0046 17.0 0.1 0.0072 16.3 0.1 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF3452 PF11934.8 ORY03778.1 - 0.045 13.3 0.1 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) zf-UBR PF02207.20 ORY03779.1 - 1.5e-18 66.7 13.6 1.5e-18 66.7 13.6 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ORY03779.1 - 2.8e-11 43.0 0.0 7.2e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Sin3_corepress PF08295.12 ORY03779.1 - 3.1 7.9 5.6 6 7.0 3.8 2.4 2 0 0 2 2 2 0 Sin3 family co-repressor TPR_1 PF00515.28 ORY03780.1 - 7.5e-13 47.7 9.8 3.6e-06 26.5 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03780.1 - 2.3e-09 36.6 7.6 0.0019 18.2 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY03780.1 - 3.7e-09 36.1 4.0 0.00058 19.9 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY03780.1 - 1.3e-05 25.3 1.9 0.0057 16.9 0.0 3.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03780.1 - 6.9e-05 22.4 3.0 0.0023 17.6 0.1 3.8 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 ORY03780.1 - 0.00077 19.6 0.3 0.64 10.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY03780.1 - 0.054 13.9 3.8 24 5.6 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY03780.1 - 0.055 14.1 4.5 1.9 9.3 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY03780.1 - 0.12 13.1 6.0 8 7.2 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY03780.1 - 0.22 11.6 4.5 0.67 10.1 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Sad1_UNC PF07738.13 ORY03781.1 - 4.2e-31 107.7 0.0 2.3e-30 105.3 0.0 1.8 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2730 PF10805.8 ORY03782.1 - 0.12 12.5 1.7 0.88 9.7 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) MitMem_reg PF13012.6 ORY03782.1 - 0.14 12.5 3.8 4.2 7.8 1.3 3.1 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function YlqD PF11068.8 ORY03782.1 - 0.17 12.3 2.6 0.36 11.2 1.9 1.9 1 1 0 1 1 1 0 YlqD protein Rootletin PF15035.6 ORY03782.1 - 0.17 11.9 3.9 0.51 10.3 3.9 1.8 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cortex-I_coil PF09304.10 ORY03782.1 - 0.41 10.9 7.5 0.32 11.2 4.4 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil DASH_Dam1 PF08653.10 ORY03782.1 - 0.53 10.1 1.9 0.8 9.5 0.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 COG2 PF06148.11 ORY03782.1 - 1.4 9.0 6.4 3.8 7.6 2.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-H PF05837.12 ORY03782.1 - 2.9 8.3 8.3 1.7 9.0 1.4 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Sas10 PF09368.10 ORY03783.1 - 6.4e-29 100.3 8.7 3.6e-28 97.9 8.7 2.4 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 ORY03783.1 - 2e-11 44.3 3.2 2e-11 44.3 3.2 3.9 4 1 1 5 5 5 1 Sas10/Utp3/C1D family zf-C3HC4_3 PF13920.6 ORY03784.1 - 0.00014 21.7 7.9 0.00026 20.8 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY03784.1 - 2.4 8.0 9.0 5.5 6.9 9.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MRP-S28 PF10213.9 ORY03786.1 - 3.1e-37 127.8 0.6 4.3e-37 127.4 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Cyclin_N PF00134.23 ORY03787.1 - 1.1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY03787.1 - 7.4e-11 42.7 0.2 9.1e-11 42.4 0.2 1.1 1 0 0 1 1 1 1 Cyclin RuvC_1 PF18516.1 ORY03787.1 - 0.0015 17.8 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 RuvC nuclease domain Peptidase_C97 PF05903.14 ORY03788.1 - 5e-22 78.4 0.1 1.2e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 ORY03788.1 - 8e-09 35.1 1.5 1.6e-08 34.1 1.5 1.5 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 ORY03788.1 - 6.4e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin LRAT PF04970.13 ORY03788.1 - 0.045 14.1 0.1 0.85 9.9 0.0 2.8 3 1 0 3 3 3 0 Lecithin retinol acyltransferase FA_hydroxylase PF04116.13 ORY03790.1 - 5.1e-25 88.4 22.0 5.1e-25 88.4 22.0 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CRAL_TRIO_2 PF13716.6 ORY03791.1 - 4.1e-34 117.7 1.4 7.7e-34 116.8 1.4 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 ORY03791.1 - 4e-32 111.2 0.0 6.2e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 ORY03791.1 - 0.00032 20.4 0.8 0.00062 19.5 0.8 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain MFS_1 PF07690.16 ORY03792.1 - 8.8e-36 123.5 49.4 4.4e-22 78.5 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY03792.1 - 5e-12 45.8 23.2 6.4e-12 45.4 23.2 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORY03792.1 - 0.00011 21.2 24.3 0.011 14.7 7.0 3.7 1 1 1 2 2 2 2 MFS_1 like family DUF4448 PF14610.6 ORY03793.1 - 0.0064 16.3 0.1 0.018 14.9 0.0 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) NTP_transferase PF00483.23 ORY03794.1 - 4.8e-33 114.8 0.0 9.4e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY03794.1 - 4.9e-08 32.4 12.9 4e-05 23.2 0.8 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY03794.1 - 8.8e-06 26.2 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY03794.1 - 0.004 16.9 0.4 0.004 16.9 0.4 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY03794.1 - 0.011 14.7 0.0 0.15 11.0 0.0 2.1 1 1 1 2 2 2 0 L-fucokinase GCP_N_terminal PF17681.1 ORY03795.1 - 5.7e-54 183.8 0.2 1.1e-53 182.9 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY03795.1 - 2.3e-42 145.5 3.8 3.7e-42 144.9 3.8 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Med31 PF05669.12 ORY03796.1 - 1.9e-36 123.9 14.4 2.5e-36 123.6 14.4 1.1 1 0 0 1 1 1 1 SOH1 DEAD PF00270.29 ORY03798.1 - 3e-50 170.4 0.0 1.2e-49 168.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY03798.1 - 1.5e-31 109.1 0.0 4.8e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY03798.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY03798.1 - 0.0092 14.8 0.0 0.51 9.1 0.0 2.6 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 ORY03798.1 - 0.011 16.0 0.0 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain GRP PF07172.11 ORY03798.1 - 0.13 13.0 17.3 0.29 11.9 17.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family Il13Ra_Ig PF18001.1 ORY03798.1 - 0.19 11.9 0.0 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain AAA_5 PF07728.14 ORY03799.1 - 1e-133 440.2 0.1 7.8e-27 94.0 0.0 8.9 7 1 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 ORY03799.1 - 5.6e-59 196.9 3.4 2.1e-22 79.3 0.1 5.8 5 0 0 5 5 5 4 Midasin AAA lid domain AAA_3 PF07726.11 ORY03799.1 - 4.3e-37 126.9 0.0 1.9e-10 40.7 0.0 7.4 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 ORY03799.1 - 7.1e-36 122.5 0.8 6e-34 116.3 0.2 3.6 4 0 0 4 4 2 1 Midasin AAA lid domain AAA PF00004.29 ORY03799.1 - 4.3e-29 101.6 0.9 5.9e-05 23.5 0.0 7.3 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY03799.1 - 3.8e-28 98.2 4.2 0.00022 20.8 0.0 6.9 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 ORY03799.1 - 4.5e-26 92.2 14.0 0.00026 21.4 0.3 7.9 6 2 0 6 6 6 6 AAA ATPase domain Dynein_heavy PF03028.15 ORY03799.1 - 9.9e-24 83.7 0.0 0.00016 21.7 0.0 7.6 9 0 0 9 9 5 5 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 ORY03799.1 - 2e-23 83.4 2.2 0.00071 20.1 0.0 7.1 6 0 0 6 6 6 5 AAA domain AAA_6 PF12774.7 ORY03799.1 - 4.7e-22 78.4 1.6 0.043 12.8 0.0 8.8 9 1 0 9 9 8 6 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 ORY03799.1 - 1.6e-21 77.0 4.6 0.0013 19.0 0.0 7.7 6 1 1 7 7 6 4 AAA domain Sigma54_activat PF00158.26 ORY03799.1 - 1e-20 74.1 0.0 0.0029 17.3 0.0 6.8 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_14 PF13173.6 ORY03799.1 - 1.7e-20 73.3 0.0 0.0014 18.7 0.0 7.9 7 0 0 7 7 7 4 AAA domain AAA_30 PF13604.6 ORY03799.1 - 1e-18 67.7 0.0 0.021 14.6 0.0 7.3 6 1 0 6 6 6 4 AAA domain TsaE PF02367.17 ORY03799.1 - 4.4e-17 62.2 6.7 0.1 12.6 0.0 6.6 6 0 0 6 6 6 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 ORY03799.1 - 9.5e-17 61.4 2.0 3.9e-05 23.8 0.0 6.5 6 0 0 6 6 6 2 Sigma-54 interaction domain ABC_tran PF00005.27 ORY03799.1 - 1.7e-16 61.0 6.9 0.036 14.6 0.2 7.5 7 0 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.12 ORY03799.1 - 6.3e-15 55.0 1.0 0.072 12.4 0.0 7.3 7 0 0 7 7 7 2 Zeta toxin Mg_chelatase PF01078.21 ORY03799.1 - 5.5e-14 52.0 2.1 0.08 12.3 0.0 8.2 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 ORY03799.1 - 7.3e-14 51.5 5.5 0.19 10.7 0.0 6.5 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_33 PF13671.6 ORY03799.1 - 4.7e-13 49.5 9.4 0.73 10.0 0.0 7.6 6 1 0 6 6 6 2 AAA domain NACHT PF05729.12 ORY03799.1 - 8.2e-13 48.6 5.2 0.31 10.9 0.0 6.4 6 0 0 6 6 5 4 NACHT domain AAA_29 PF13555.6 ORY03799.1 - 1.7e-11 43.7 1.3 1.3 8.8 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_28 PF13521.6 ORY03799.1 - 4.9e-11 43.2 11.5 0.33 11.2 0.0 7.4 8 0 0 8 8 7 3 AAA domain RNA_helicase PF00910.22 ORY03799.1 - 5e-11 43.0 2.1 1.1 9.7 0.0 6.5 6 0 0 6 6 6 2 RNA helicase RsgA_GTPase PF03193.16 ORY03799.1 - 1.6e-10 41.1 6.0 1 9.3 0.1 6.4 6 0 0 6 6 6 2 RsgA GTPase DUF815 PF05673.13 ORY03799.1 - 3.3e-10 39.6 4.4 0.42 9.7 0.0 6.5 6 0 0 6 6 6 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY03799.1 - 1.6e-09 37.7 4.8 2.5 7.8 0.0 7.5 7 1 0 8 8 7 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ORY03799.1 - 1.9e-09 37.5 1.0 0.59 9.8 0.0 6.8 7 0 0 7 7 6 1 IstB-like ATP binding protein PduV-EutP PF10662.9 ORY03799.1 - 1.3e-08 34.7 4.1 0.047 13.4 0.0 6.0 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 ORY03799.1 - 2.5e-08 34.4 7.8 0.75 10.1 0.2 7.2 6 2 0 6 6 5 1 AAA domain AAA_25 PF13481.6 ORY03799.1 - 2.6e-08 33.7 4.4 0.27 10.8 0.0 5.7 6 0 0 6 6 5 1 AAA domain SRP54 PF00448.22 ORY03799.1 - 3.3e-08 33.4 3.3 0.27 10.8 0.0 6.3 7 0 0 7 7 6 2 SRP54-type protein, GTPase domain Rad17 PF03215.15 ORY03799.1 - 3e-07 30.5 4.6 2 8.3 0.0 6.0 7 0 0 7 7 5 1 Rad17 P-loop domain AAA_8 PF12780.7 ORY03799.1 - 5.7e-07 29.1 1.1 6.5 6.0 0.0 6.3 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 AAA_24 PF13479.6 ORY03799.1 - 6.2e-07 29.3 2.6 3.5 7.3 0.0 6.2 7 0 0 7 7 6 0 AAA domain AAA_2 PF07724.14 ORY03799.1 - 1.2e-06 28.8 0.1 4.5 7.4 0.0 6.5 6 0 0 6 6 6 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 ORY03799.1 - 1.3e-06 28.4 0.1 3.5 7.3 0.0 6.0 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 ORY03799.1 - 1.4e-06 28.5 3.6 14 6.0 0.0 6.2 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY03799.1 - 1.7e-06 27.7 7.0 3.3 7.3 0.1 6.6 7 0 0 7 7 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 ORY03799.1 - 1.8e-06 28.6 13.2 1 9.8 0.1 7.0 6 1 0 6 6 6 2 AAA domain NTPase_1 PF03266.15 ORY03799.1 - 5.1e-06 26.5 5.1 4 7.3 0.1 6.0 5 0 0 5 5 5 0 NTPase TniB PF05621.11 ORY03799.1 - 5.4e-06 25.9 0.5 2.2 7.6 0.0 5.6 6 0 0 6 6 5 1 Bacterial TniB protein ATPase_2 PF01637.18 ORY03799.1 - 1.2e-05 25.3 1.8 12 5.8 0.0 6.5 7 1 0 7 7 6 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 ORY03799.1 - 2.2e-05 24.5 2.2 5.6 7.1 0.1 5.5 5 0 0 5 5 5 0 50S ribosome-binding GTPase CPT PF07931.12 ORY03799.1 - 2.4e-05 24.2 3.7 5.9 6.7 0.0 7.0 7 1 0 7 7 5 0 Chloramphenicol phosphotransferase-like protein MCM PF00493.23 ORY03799.1 - 2.8e-05 23.3 0.1 4.9 6.2 0.0 5.1 5 1 0 5 5 5 0 MCM P-loop domain AAA_9 PF12781.7 ORY03799.1 - 3e-05 23.3 1.4 0.48 9.5 0.0 5.6 6 0 0 6 6 6 1 ATP-binding dynein motor region DEAD PF00270.29 ORY03799.1 - 9.1e-05 22.3 0.1 7.8 6.2 0.0 5.1 5 0 0 5 5 5 0 DEAD/DEAH box helicase CbiA PF01656.23 ORY03799.1 - 0.00025 21.1 1.7 8.5 6.5 0.2 4.8 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 ORY03799.1 - 0.00031 20.2 5.0 2.5 7.4 0.0 5.3 6 0 0 6 6 5 0 KaiC DnaB_C PF03796.15 ORY03799.1 - 0.00057 19.3 0.3 0.31 10.4 0.0 3.7 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_21 PF13304.6 ORY03799.1 - 0.00057 19.8 1.0 4.7 6.9 0.1 4.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 ORY03799.1 - 0.00063 19.7 10.1 5 6.9 0.0 6.8 7 0 0 7 7 6 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 ORY03799.1 - 0.00068 19.5 14.2 0.45 10.3 0.1 6.6 8 0 0 8 8 5 1 Conserved hypothetical ATP binding protein TIP49 PF06068.13 ORY03799.1 - 0.00093 18.5 2.2 14 4.8 0.1 5.1 6 0 0 6 6 5 0 TIP49 P-loop domain SRPRB PF09439.10 ORY03799.1 - 0.0011 18.5 2.4 71 2.8 0.0 6.0 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 ORY03799.1 - 0.0014 18.6 3.5 2.1 8.3 0.5 4.9 5 1 0 5 5 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 ORY03799.1 - 0.0019 18.1 0.1 33 4.1 0.0 5.3 6 0 0 6 6 4 0 AAA domain PRK PF00485.18 ORY03799.1 - 0.0021 17.8 1.4 2.9 7.6 0.0 4.6 5 0 0 5 5 3 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 ORY03799.1 - 0.003 17.0 0.7 7.9 5.9 0.0 4.5 6 0 0 6 6 4 0 PhoH-like protein Thymidylate_kin PF02223.17 ORY03799.1 - 0.0049 16.6 4.8 3.6 7.2 0.0 5.6 6 0 0 6 6 6 0 Thymidylate kinase DUF87 PF01935.17 ORY03799.1 - 0.0086 16.2 1.4 8.4 6.4 0.0 4.4 4 0 0 4 4 4 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 ORY03799.1 - 0.012 15.3 0.1 8.7 5.9 0.1 3.7 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 ORY03799.1 - 0.03 14.1 0.2 24 4.5 0.0 3.8 4 0 0 4 4 3 0 AAA ATPase domain Septin PF00735.18 ORY03799.1 - 0.036 13.4 1.0 25 4.0 0.0 4.3 5 0 0 5 5 4 0 Septin APS_kinase PF01583.20 ORY03799.1 - 0.036 13.9 0.8 31 4.4 0.0 4.5 4 0 0 4 4 4 0 Adenylylsulphate kinase IPT PF01745.16 ORY03799.1 - 0.055 12.9 0.9 8.7 5.7 0.0 4.1 5 0 0 5 5 3 0 Isopentenyl transferase MobB PF03205.14 ORY03799.1 - 0.058 13.3 9.3 18 5.2 0.0 6.2 7 0 0 7 7 7 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 ORY03799.1 - 0.064 12.6 1.2 27 4.0 0.0 3.9 4 0 0 4 4 3 0 FtsK/SpoIIIE family Cytidylate_kin PF02224.18 ORY03799.1 - 0.069 12.9 0.0 25 4.5 0.0 4.1 4 0 0 4 4 4 0 Cytidylate kinase SMC_N PF02463.19 ORY03799.1 - 0.13 11.7 0.3 13 5.2 0.0 3.7 4 0 0 4 4 3 0 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.9 ORY03799.1 - 0.15 10.9 6.9 20 3.9 0.0 5.6 7 0 0 7 7 7 0 Type IV secretion-system coupling protein DNA-binding domain G-alpha PF00503.20 ORY03799.1 - 0.41 9.7 9.1 15 4.6 0.5 4.4 4 0 0 4 4 3 0 G-protein alpha subunit FeoB_N PF02421.18 ORY03799.1 - 0.45 10.0 2.2 35 3.9 0.0 4.0 5 0 0 5 5 3 0 Ferrous iron transport protein B SKI PF01202.22 ORY03799.1 - 1.3 9.1 5.0 1.1e+02 2.9 0.0 5.1 6 0 0 6 6 4 0 Shikimate kinase AAA_17 PF13207.6 ORY03799.1 - 1.6 9.2 9.1 47 4.4 0.0 6.2 7 0 0 7 7 5 0 AAA domain Ribosomal_S17e PF00833.18 ORY03800.1 - 5e-65 216.9 0.2 5.8e-65 216.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Arrestin_C PF02752.22 ORY03801.1 - 4.5e-09 36.9 0.0 4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY03801.1 - 0.0042 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Asp PF00026.23 ORY03802.1 - 4.3e-88 295.8 4.1 4.6e-75 253.0 3.1 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY03802.1 - 1.5e-12 48.1 8.4 4.5e-09 36.8 0.3 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY03802.1 - 0.00011 22.7 0.2 0.049 14.3 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY03802.1 - 0.0085 16.6 0.1 8.2 7.1 0.1 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp PF00026.23 ORY03803.1 - 2.3e-95 319.7 2.5 2.7e-95 319.4 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY03803.1 - 2.8e-11 44.0 5.9 5.3e-08 33.3 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY03803.1 - 0.00019 22.0 0.1 0.18 12.5 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY03803.1 - 0.013 16.0 0.2 7.8 7.1 0.1 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease UIM PF02809.20 ORY03804.1 - 0.00091 19.0 3.3 0.0019 18.0 3.3 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Prok-RING_4 PF14447.6 ORY03804.1 - 0.063 13.2 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2318 PF10080.9 ORY03804.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) UBZ_FAAP20 PF15750.5 ORY03804.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DUF4834 PF16118.5 ORY03804.1 - 0.19 12.7 1.9 0.25 12.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sugar_tr PF00083.24 ORY03805.1 - 9.2e-55 186.3 16.7 1.1e-54 186.0 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY03805.1 - 1.1e-25 90.3 28.8 2.1e-25 89.4 26.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY03805.1 - 1.9e-06 27.4 3.5 4.2e-06 26.3 3.5 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORY03805.1 - 1.7e-05 23.6 5.7 1.7e-05 23.6 5.7 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORY03805.1 - 0.0094 15.5 0.7 0.026 14.1 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF417 OATP PF03137.20 ORY03805.1 - 1.9 6.7 10.9 0.57 8.4 2.6 3.0 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GFO_IDH_MocA PF01408.22 ORY03806.1 - 1.8e-20 73.9 0.1 2.7e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_3 PF01494.19 ORY03807.1 - 4.2e-75 253.2 0.0 5.2e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY03807.1 - 0.0048 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY03807.1 - 0.011 15.4 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY03807.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORY03807.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY03807.1 - 0.013 14.6 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ORY03807.1 - 0.026 14.2 0.1 0.067 12.8 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 ORY03807.1 - 0.035 13.5 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 ORY03807.1 - 0.056 12.1 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 ORY03807.1 - 0.097 11.9 0.1 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 ORY03807.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 ORY03808.1 - 3.4e-81 273.0 0.0 4.5e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ORY03808.1 - 3.4e-73 246.3 0.2 1.4e-72 244.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY03808.1 - 7.1e-39 132.5 0.5 1.4e-38 131.6 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ORY03808.1 - 7.7e-16 58.6 0.1 4e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 ORY03808.1 - 7e-10 39.8 0.2 3.7e-09 37.4 0.2 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 ORY03808.1 - 6.5e-07 29.0 0.5 4.3e-06 26.3 0.2 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain PP-binding PF00550.25 ORY03808.1 - 7.3e-06 26.2 0.0 3.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 ORY03808.1 - 6.3e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain ACP_syn_III PF08545.10 ORY03808.1 - 0.15 12.0 4.6 0.67 9.8 1.3 3.0 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioesterase PF00975.20 ORY03809.1 - 9.3e-16 58.6 0.0 2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 ORY03809.1 - 1.2e-11 44.8 0.0 3.4e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 ORY03809.1 - 1.3e-10 42.3 0.0 2.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY03809.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 ORY03809.1 - 0.00033 20.2 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 ORY03809.1 - 0.00042 20.1 0.0 0.00097 18.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 ORY03809.1 - 0.002 17.8 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORY03809.1 - 0.0056 16.0 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORY03809.1 - 0.026 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 ORY03809.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.14 ORY03809.1 - 0.049 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 ORY03809.1 - 0.051 12.5 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 ORY03809.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase PF00151.19 ORY03809.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipase MIP PF00230.20 ORY03810.1 - 0.0049 16.6 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Oxidored_molyb PF00174.19 ORY03811.1 - 1.4e-54 184.2 0.0 2.4e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY03811.1 - 1.3e-39 135.3 0.2 2.8e-39 134.3 0.2 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 ORY03811.1 - 1.9e-34 118.0 0.0 4.3e-34 116.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY03811.1 - 9.8e-29 100.2 0.0 4.2e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORY03811.1 - 1.5e-21 76.3 0.1 5.4e-21 74.5 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORY03811.1 - 4.9e-06 26.7 0.0 1.6e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain CBAH PF02275.18 ORY03812.1 - 0.014 15.1 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family COG5 PF10392.9 ORY03813.1 - 0.045 13.9 0.3 0.14 12.3 0.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 V-ATPase_G PF03179.15 ORY03813.1 - 0.52 10.9 2.9 0.43 11.1 0.5 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Helicase_C PF00271.31 ORY03814.1 - 2.5e-05 24.6 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain C_Hendra PF16821.5 ORY03815.1 - 0.04 13.8 0.4 0.04 13.8 0.4 2.3 3 0 0 3 3 3 0 C protein from hendra and measles viruses DUF3535 PF12054.8 ORY03815.1 - 1.7 7.8 6.5 0.076 12.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) SDH_alpha PF03313.15 ORY03866.1 - 3.9e-105 351.2 0.0 5.3e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORY03866.1 - 1.5e-57 194.3 0.0 6.2e-57 192.3 0.0 2.0 2 0 0 2 2 2 1 Serine dehydratase beta chain Pkinase PF00069.25 ORY03867.1 - 9.4e-73 244.8 0.0 1.3e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03867.1 - 1.3e-49 168.9 0.0 2e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY03867.1 - 7.5e-05 21.7 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY03867.1 - 0.0012 18.3 0.0 0.0034 16.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY03867.1 - 0.03 13.3 0.0 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain ABC1 PF03109.16 ORY03867.1 - 0.04 14.1 0.1 0.95 9.6 0.0 2.8 3 0 0 3 3 3 0 ABC1 family YlbD_coat PF14071.6 ORY03867.1 - 0.33 11.2 4.2 1.6 9.0 0.2 2.7 3 0 0 3 3 3 0 Putative coat protein Atg8 PF02991.16 ORY03868.1 - 6.2e-52 174.1 0.2 7.3e-52 173.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORY03868.1 - 5.7e-06 26.6 0.0 7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 VPS9 PF02204.18 ORY03869.1 - 8.4e-33 112.7 0.2 1.6e-32 111.8 0.2 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SNARE PF05739.19 ORY03869.1 - 0.011 15.7 1.3 0.02 14.9 0.0 2.0 2 0 0 2 2 2 0 SNARE domain ADH_zinc_N PF00107.26 ORY03870.1 - 3.3e-26 91.8 0.0 5.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY03870.1 - 3.5e-17 63.7 0.0 1.3e-15 58.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY03870.1 - 2.4e-09 37.0 0.0 5.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PUF PF00806.19 ORY03873.1 - 3.7e-63 205.8 14.0 8.1e-10 37.8 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 ORY03873.1 - 4.1e-07 29.7 4.7 1.3e-06 28.1 4.7 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY03873.1 - 5.5e-07 29.4 6.0 1.7e-06 27.9 6.0 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 ORY03873.1 - 1.5e-06 27.8 3.8 1.5e-06 27.8 3.8 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 ORY03873.1 - 0.00084 20.0 0.3 0.0024 18.6 0.0 1.9 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 ORY03873.1 - 0.0013 19.1 3.3 0.0043 17.5 3.3 1.9 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ORY03873.1 - 0.11 12.7 0.8 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger containing family LOB PF03195.14 ORY03873.1 - 2.3 8.8 5.0 12 6.6 0.0 4.1 3 1 3 6 6 6 0 Lateral organ boundaries (LOB) domain Complex1_LYR_2 PF13233.6 ORY03874.1 - 5.5e-14 52.7 2.2 7.2e-14 52.3 2.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Taxilin PF09728.9 ORY03874.1 - 0.0037 16.5 1.1 0.0044 16.2 1.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein FF PF01846.19 ORY03874.1 - 0.031 14.5 0.9 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 FF domain MOR2-PAG1_N PF14222.6 ORY03874.1 - 0.057 12.4 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Y_phosphatase PF00102.27 ORY03875.1 - 2.4e-07 30.5 0.0 3.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY03875.1 - 2.7e-06 27.2 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORY03875.1 - 0.01 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 ORY03875.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DRIM PF07539.12 ORY03876.1 - 2.8e-193 643.6 3.6 2.8e-193 643.6 3.6 5.0 4 1 1 6 6 6 2 Down-regulated in metastasis Dopey_N PF04118.14 ORY03876.1 - 0.92 8.6 8.1 0.93 8.5 0.0 4.0 4 0 0 4 4 4 0 Dopey, N-terminal Striatin PF08232.12 ORY03877.1 - 3.4e-45 154.4 0.2 3.4e-45 154.4 0.2 2.9 3 0 0 3 3 3 1 Striatin family WD40 PF00400.32 ORY03877.1 - 3.5e-36 122.6 18.7 2.5e-06 28.1 0.5 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY03877.1 - 7.7e-13 48.6 0.3 0.73 10.2 0.0 5.9 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY03877.1 - 0.024 13.6 0.1 27 3.6 0.0 3.6 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TIMELESS PF04821.14 ORY03877.1 - 0.11 11.7 0.3 0.4 9.9 0.1 2.0 2 0 0 2 2 2 0 Timeless protein Aminotran_4 PF01063.19 ORY03878.1 - 7.4e-17 61.9 0.0 1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV HA2 PF04408.23 ORY03879.1 - 1e-17 64.3 0.0 3.1e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY03879.1 - 1.6e-13 50.9 0.0 4.6e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORY03879.1 - 4.3e-13 49.4 0.2 1.2e-12 48.0 0.2 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORY03879.1 - 2.4e-07 30.7 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY03879.1 - 2.8e-05 24.5 0.1 0.00012 22.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY03879.1 - 0.00085 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein LPP20 PF02169.16 ORY03879.1 - 0.0079 16.5 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 LPP20 lipoprotein ResIII PF04851.15 ORY03879.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY03879.1 - 0.041 13.6 0.3 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY03879.1 - 0.052 12.9 1.0 0.12 11.7 0.1 2.0 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.6 ORY03879.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.9 ORY03879.1 - 0.099 12.5 0.1 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HSF_DNA-bind PF00447.17 ORY03880.1 - 1.8e-34 118.2 0.9 4.1e-34 117.1 0.9 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 ORY03880.1 - 0.085 13.3 0.3 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Ets-domain Mak10 PF04112.13 ORY03881.1 - 1.4e-51 174.4 0.2 2.4e-51 173.6 0.2 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FAD_binding_3 PF01494.19 ORY03882.1 - 2.2e-26 92.9 0.0 8.4e-26 91.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY03882.1 - 6e-06 25.5 0.0 2.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 ORY03882.1 - 1.3e-05 24.6 0.0 0.00016 21.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY03882.1 - 2.7e-05 23.9 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY03882.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 ORY03882.1 - 0.00027 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ORY03882.1 - 0.00038 20.6 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY03882.1 - 0.00086 19.8 0.0 0.0061 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY03882.1 - 0.018 13.7 0.0 0.058 12.1 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ORY03882.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 ORY03882.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 ORY03882.1 - 0.055 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ORY03882.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynamin_M PF01031.20 ORY03883.1 - 1.1e-100 336.5 0.1 1.1e-100 336.5 0.1 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ORY03883.1 - 2.1e-57 193.8 0.0 4.1e-57 192.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY03883.1 - 6.4e-31 106.4 6.9 1.7e-30 105.0 6.9 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY03883.1 - 0.00031 20.8 0.4 0.0027 17.8 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase HECT PF00632.25 ORY03884.1 - 3.4e-91 305.9 0.3 4.6e-91 305.5 0.3 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Actin PF00022.19 ORY03885.1 - 5.4e-154 512.7 0.0 6.1e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY03885.1 - 0.0092 14.8 0.0 0.031 13.1 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Ras PF00071.22 ORY03886.1 - 1.2e-59 200.5 0.0 1.5e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY03886.1 - 7.6e-36 123.0 0.0 1.4e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY03886.1 - 2.3e-12 46.7 0.0 3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY03886.1 - 4.9e-06 26.6 0.0 7.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY03886.1 - 5.9e-06 25.8 0.0 7.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY03886.1 - 7.4e-06 26.0 0.2 0.13 12.2 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORY03886.1 - 0.00014 21.5 0.0 0.0004 20.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORY03886.1 - 0.012 16.0 0.1 0.025 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 ORY03886.1 - 0.1 12.0 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 ORY03886.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 ORY03886.1 - 0.15 11.4 0.0 8.9 5.6 0.0 2.1 2 0 0 2 2 2 0 KaiC RabGAP-TBC PF00566.18 ORY03887.1 - 8.9e-42 143.2 0.3 1.4e-41 142.6 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OST3_OST6 PF04756.13 ORY03888.1 - 3.8e-30 105.3 0.0 4.5e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 ORY03888.1 - 0.036 14.0 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF236 PF03057.14 ORY03888.1 - 0.2 11.6 0.2 0.6 10.1 0.0 1.8 2 0 0 2 2 2 0 DUF236 repeat Pkinase PF00069.25 ORY03889.1 - 2.3e-65 220.6 0.0 2.7e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03889.1 - 1.1e-23 83.8 0.0 1.6e-23 83.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY03889.1 - 0.0019 17.6 0.0 0.0044 16.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like ABC1 PF03109.16 ORY03889.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 ORY03889.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY03889.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 ORY03889.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase eIF3g PF12353.8 ORY03890.1 - 0.5 10.8 2.6 2.1 8.7 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Glutaredoxin PF00462.24 ORY03890.1 - 1.1 9.5 3.3 29 5.0 0.1 3.5 4 0 0 4 4 4 0 Glutaredoxin Uso1_p115_head PF04869.14 ORY03892.1 - 5.9e-73 245.7 0.4 3e-72 243.4 0.0 2.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 ORY03892.1 - 3.6e-08 33.2 0.1 8.8e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 ORY03892.1 - 8.5e-07 29.4 16.5 1.7e-06 28.4 16.5 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tup_N PF08581.10 ORY03892.1 - 4.9e-05 23.6 6.6 4.9e-05 23.6 6.6 2.5 1 1 1 2 2 2 1 Tup N-terminal RTP1_C1 PF10363.9 ORY03892.1 - 0.00019 21.6 2.5 0.58 10.4 0.0 4.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 ATG16 PF08614.11 ORY03892.1 - 0.00025 21.4 8.9 0.00058 20.1 8.9 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Cnn_1N PF07989.11 ORY03892.1 - 0.0052 16.9 8.8 0.017 15.3 8.8 1.8 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 HMMR_N PF15905.5 ORY03892.1 - 0.0087 15.6 11.6 0.015 14.8 11.6 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF3361 PF11841.8 ORY03892.1 - 0.01 15.8 3.7 0.096 12.6 0.0 3.1 2 2 2 4 4 4 0 Domain of unknown function (DUF3361) NYD-SP28 PF14772.6 ORY03892.1 - 0.012 15.6 8.0 0.012 15.6 8.0 2.1 1 1 1 2 2 2 0 Sperm tail TPR_MLP1_2 PF07926.12 ORY03892.1 - 0.033 14.2 9.4 0.082 13.0 9.4 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 ORY03892.1 - 0.034 13.6 7.2 0.079 12.4 7.2 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 DNA_repr_REX1B PF14966.6 ORY03892.1 - 0.04 14.6 3.3 2.7 8.7 0.9 2.7 2 0 0 2 2 2 0 DNA repair REX1-B Atg14 PF10186.9 ORY03892.1 - 0.042 12.9 2.2 0.074 12.1 2.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 ORY03892.1 - 0.077 12.8 14.0 0.39 10.5 8.9 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 Cnd1 PF12717.7 ORY03892.1 - 0.11 12.6 3.1 0.29 11.2 0.7 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1840 PF08895.11 ORY03892.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Fib_alpha PF08702.10 ORY03892.1 - 0.47 10.6 9.8 1 9.6 8.2 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YjbH PF06082.11 ORY03892.1 - 1.9 7.2 5.2 2.9 6.6 5.2 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Prefoldin PF02996.17 ORY03892.1 - 4.6 7.2 11.2 4.6 7.2 4.6 2.8 1 1 1 2 2 2 0 Prefoldin subunit Csm1_N PF18504.1 ORY03892.1 - 7 7.1 10.8 24 5.4 9.8 2.4 1 1 0 1 1 1 0 Csm1 N-terminal domain Cob_adeno_trans PF01923.18 ORY03893.1 - 2.3e-56 190.4 0.0 3e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Myb_DNA-bind_4 PF13837.6 ORY03894.1 - 1.5e-19 70.1 1.5 1.5e-19 70.1 1.5 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY03894.1 - 4.1e-08 33.4 1.8 4.1e-08 33.4 1.8 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY03894.1 - 6.3e-08 32.7 0.7 1.5e-07 31.5 0.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY03894.1 - 0.00028 21.1 0.5 0.00028 21.1 0.5 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 ORY03894.1 - 0.065 14.2 0.9 0.065 14.2 0.9 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3915 PF13054.6 ORY03894.1 - 1.2 9.1 3.8 2.8 8.0 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ion_trans PF00520.31 ORY03895.1 - 9.9e-08 31.5 1.5 1.1e-07 31.3 1.5 1.0 1 0 0 1 1 1 1 Ion transport protein TauD PF02668.16 ORY03897.1 - 0.00089 19.1 0.0 0.00089 19.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1729 PF08354.10 ORY03898.1 - 7.4e-145 482.3 0.0 1.5e-144 481.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ORY03898.1 - 2.8e-61 207.8 0.0 2.6e-60 204.6 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 ORY03898.1 - 1.1e-60 204.7 0.1 3.9e-60 202.9 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 ORY03898.1 - 2.1e-48 164.6 0.3 4.2e-48 163.7 0.3 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain FAS_meander PF17951.1 ORY03898.1 - 3.3e-34 117.8 0.0 1.4e-33 115.8 0.0 2.2 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 ORY03898.1 - 4.2e-29 102.0 0.0 8.9e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 ORY03898.1 - 3.7e-25 87.9 0.1 1.4e-24 86.0 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.26 ORY03898.1 - 4.6e-16 59.2 0.0 1.1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY03898.1 - 3.7e-15 56.0 0.0 1.4e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 ORY03898.1 - 7.2e-15 55.1 0.0 2.2e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 ORY03898.1 - 1e-07 32.1 0.2 4.3e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 ORY03898.1 - 1.1e-07 31.9 0.4 1.7e-06 28.0 0.1 2.6 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta Malate_synthase PF01274.22 ORY03899.1 - 8.4e-224 743.7 0.0 9.5e-224 743.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase CDP-OH_P_transf PF01066.21 ORY03900.1 - 5.2e-13 49.6 0.3 5.2e-13 49.6 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FAM165 PF14981.6 ORY03900.1 - 0.18 11.6 2.2 2 8.3 0.3 2.3 2 0 0 2 2 2 0 FAM165 family Hydrolase_4 PF12146.8 ORY03901.1 - 8.7e-15 54.6 0.1 1.2e-11 44.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY03901.1 - 2.3e-10 40.6 0.1 4.5e-08 33.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY03901.1 - 3.4e-08 34.3 0.0 4.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY03901.1 - 6.2e-08 32.4 0.6 5.4e-06 26.0 0.1 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY03901.1 - 0.0038 16.9 0.0 0.072 12.7 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 ORY03901.1 - 0.0038 16.9 0.1 0.03 14.0 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY03901.1 - 0.012 15.4 0.2 0.65 9.8 0.0 2.8 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 ORY03901.1 - 0.014 15.4 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 ORY03901.1 - 0.019 14.3 0.1 0.42 9.9 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.10 ORY03901.1 - 0.056 12.5 0.1 0.43 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Esterase PF00756.20 ORY03901.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 1 1 2 2 2 0 Putative esterase Abhydrolase_4 PF08386.10 ORY03901.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein TFIIB PF00382.19 ORY03902.1 - 1e-45 153.7 0.2 2.5e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY03902.1 - 3.9e-15 55.1 1.4 6.6e-15 54.3 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 ORY03902.1 - 7e-05 22.9 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 ORY03902.1 - 0.004 16.9 0.1 0.062 13.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Guanylin PF02058.15 ORY03902.1 - 0.021 15.3 0.9 6.8 7.2 0.2 3.1 1 1 2 3 3 3 0 Guanylin precursor TMIE PF16038.5 ORY03902.1 - 0.097 12.5 1.4 0.2 11.5 0.8 1.8 2 0 0 2 2 2 0 TMIE protein Sigma70_r4_2 PF08281.12 ORY03902.1 - 0.13 12.0 0.5 1.1 9.0 0.0 2.8 4 0 0 4 4 4 0 Sigma-70, region 4 RB_B PF01857.20 ORY03902.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain UPF0183 PF03676.14 ORY03903.1 - 8.4e-108 361.1 0.0 1.1e-107 360.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) RhoGAP PF00620.27 ORY03904.1 - 1.1e-37 129.1 0.0 1.9e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TPR_1 PF00515.28 ORY03906.1 - 9e-13 47.5 6.2 9.9e-05 22.0 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat PB1 PF00564.24 ORY03906.1 - 2.2e-11 43.5 2.3 4.6e-11 42.5 2.3 1.6 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 ORY03906.1 - 6.3e-08 32.2 10.5 0.044 13.9 0.0 5.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY03906.1 - 5.2e-07 29.4 6.4 0.0027 17.8 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY03906.1 - 0.00013 22.2 3.0 0.0025 18.0 0.4 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03906.1 - 0.011 15.4 0.6 0.053 13.2 0.0 2.5 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 ORY03906.1 - 0.062 13.4 0.5 0.42 10.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ITI_HC_C PF06668.12 ORY03906.1 - 0.088 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus NUDIX PF00293.28 ORY03907.1 - 2.5e-26 92.2 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2075 PF09848.9 ORY03907.1 - 0.0082 15.4 0.4 0.33 10.1 0.1 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Aa_trans PF01490.18 ORY03961.1 - 4e-63 213.5 39.5 4.6e-63 213.3 39.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY03961.1 - 0.00014 20.8 30.9 0.00014 20.8 30.9 2.4 1 1 1 2 2 2 1 Amino acid permease EBP PF05241.12 ORY03962.1 - 1.1e-55 187.8 5.5 1.4e-55 187.5 5.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein Pkinase PF00069.25 ORY03963.1 - 1.3e-71 241.0 0.0 1.5e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY03963.1 - 3.6e-55 187.1 0.0 4.5e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY03963.1 - 2.7e-05 23.8 0.1 0.00012 21.8 0.0 1.8 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 ORY03963.1 - 0.00025 20.7 0.4 0.00045 19.8 0.1 1.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 ORY03963.1 - 0.00037 19.9 0.0 0.0034 16.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 ORY03963.1 - 0.0024 17.0 0.1 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 ORY03963.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Septin PF00735.18 ORY03964.1 - 3e-113 377.8 0.6 4.2e-113 377.3 0.6 1.1 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 ORY03964.1 - 1.9e-08 34.1 1.0 8.1e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY03964.1 - 3.1e-08 33.7 0.0 7.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY03964.1 - 1.3e-06 28.4 0.7 1.1e-05 25.4 0.3 2.4 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORY03964.1 - 6.6e-05 23.1 0.3 0.00015 22.0 0.3 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 ORY03964.1 - 0.00019 20.9 0.1 0.00019 20.9 0.1 1.8 2 0 0 2 2 2 1 AIG1 family Pox_A32 PF04665.12 ORY03964.1 - 0.00023 20.7 0.2 0.00052 19.6 0.2 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_16 PF13191.6 ORY03964.1 - 0.0021 18.5 0.0 0.0062 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY03964.1 - 0.0024 18.1 0.2 0.0079 16.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain Ras PF00071.22 ORY03964.1 - 0.0049 16.5 0.4 0.023 14.3 0.2 2.1 2 0 0 2 2 2 1 Ras family PduV-EutP PF10662.9 ORY03964.1 - 0.0093 15.7 0.5 0.17 11.6 0.2 2.4 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 ORY03964.1 - 0.014 14.5 0.0 0.041 12.9 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 ORY03964.1 - 0.019 14.7 0.1 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 ORY03964.1 - 0.023 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 ORY03964.1 - 0.025 13.9 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 ORY03964.1 - 0.029 14.3 0.2 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 ORY03964.1 - 0.03 14.8 0.3 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 ORY03964.1 - 0.044 13.5 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 ORY03964.1 - 0.053 13.9 0.1 0.22 11.9 0.0 2.1 2 1 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 ORY03964.1 - 0.091 12.3 1.0 0.14 11.7 0.2 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 ORY03964.1 - 0.12 11.9 0.4 0.76 9.3 0.4 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY03964.1 - 0.12 12.1 0.8 5.6 6.7 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ORY03964.1 - 0.13 12.2 0.9 8.4 6.3 0.3 2.4 2 0 0 2 2 2 0 NTPase zf-C2H2_aberr PF17017.5 ORY03965.1 - 4.7e-06 26.9 7.1 0.019 15.1 1.1 2.9 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY03965.1 - 0.00059 20.2 15.4 0.027 14.9 1.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY03965.1 - 0.02 15.5 8.9 1.7 9.3 0.1 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain zf_Hakai PF18408.1 ORY03965.1 - 0.041 13.6 2.5 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 ORY03965.1 - 0.21 12.5 17.7 0.75 10.8 1.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_M1 PF01433.20 ORY03966.1 - 1.8e-46 158.4 0.0 2.6e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORY03966.1 - 3.6e-42 143.0 0.0 7e-42 142.1 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORY03966.1 - 1.5e-26 93.7 0.0 2.1e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 ORY03966.1 - 0.082 12.6 0.3 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Peptidase MA superfamily JmjC PF02373.22 ORY03967.1 - 9e-07 29.3 0.1 3e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase RabGAP-TBC PF00566.18 ORY03968.1 - 9.8e-48 162.6 0.6 1.5e-47 162.1 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NAD_binding_6 PF08030.12 ORY03969.1 - 8.9e-35 120.1 0.0 1.6e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY03969.1 - 3.1e-20 72.3 0.0 7e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ORY03969.1 - 4.5e-18 65.6 13.0 4.5e-18 65.6 13.0 2.3 1 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ORY03969.1 - 0.032 14.9 0.0 0.12 13.0 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain HLH PF00010.26 ORY03971.1 - 1.6e-14 53.5 1.5 2.6e-14 52.9 1.5 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5345 PF17280.2 ORY03971.1 - 0.42 10.6 2.3 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Homeodomain PF00046.29 ORY03972.1 - 2e-12 46.7 0.3 6.1e-12 45.2 0.3 1.9 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY03972.1 - 9.6e-10 38.2 0.1 9.6e-10 38.2 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 ORY03972.1 - 0.097 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Plasmo_rep PF12135.8 ORY03972.1 - 0.2 11.2 0.3 0.5 10.0 0.3 1.7 1 0 0 1 1 1 0 Plasmodium repeat family LysM PF01476.20 ORY03973.1 - 3.3e-06 27.0 0.3 1e-05 25.5 0.1 2.0 2 0 0 2 2 2 1 LysM domain RasGEF PF00617.19 ORY03974.1 - 3.5e-57 193.5 2.9 5.3e-57 192.9 2.9 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY03974.1 - 5.3e-23 81.3 1.1 1.2e-22 80.1 0.2 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Branch PF02485.21 ORY03974.1 - 0.039 13.5 0.1 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Core-2/I-Branching enzyme AROS PF15684.5 ORY03974.1 - 0.24 12.0 1.1 2.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Acyl-CoA_dh_1 PF00441.24 ORY03975.1 - 4.5e-29 101.6 0.3 8.2e-29 100.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY03975.1 - 1.9e-28 99.4 0.0 3.8e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY03975.1 - 4.9e-21 74.7 0.0 8.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY03975.1 - 1.1e-06 28.9 0.1 2.1e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Aldo_ket_red PF00248.21 ORY03976.1 - 8.9e-06 25.1 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Rgp1 PF08737.10 ORY03977.1 - 2e-82 277.6 1.4 9.8e-81 272.0 1.4 2.4 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 ORY03977.1 - 0.00052 20.1 0.1 0.011 15.8 0.0 2.8 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L28 PF00830.19 ORY03978.1 - 2.2e-20 72.6 0.8 3.7e-20 71.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal L28 family zf-C2H2_aberr PF17017.5 ORY03979.1 - 0.0073 16.5 4.0 0.54 10.4 1.9 2.1 2 0 0 2 2 2 2 Aberrant zinc-finger PCNP PF15473.6 ORY03979.1 - 0.0091 16.7 0.1 0.012 16.3 0.1 1.1 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family Ogr_Delta PF04606.12 ORY03979.1 - 0.018 15.0 1.3 2.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2 PF00096.26 ORY03979.1 - 0.044 14.2 2.9 0.044 14.2 2.9 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type ARS2 PF04959.13 ORY03979.1 - 0.1 13.0 2.0 0.25 11.7 0.7 2.1 2 1 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 ORY03979.1 - 0.47 11.4 21.3 0.47 11.4 3.4 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.25 ORY03980.1 - 5.2e-71 239.6 0.0 8.4e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GerA PF03323.13 ORY03981.1 - 0.0082 14.7 0.1 0.009 14.5 0.1 1.1 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein DHHC PF01529.20 ORY03982.1 - 1.1e-35 122.6 12.7 2e-35 121.8 12.7 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase zf-RanBP PF00641.18 ORY03982.1 - 0.029 13.7 4.3 0.072 12.4 4.3 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-PARP PF00645.18 ORY03983.1 - 3.3e-19 69.5 0.0 7.5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ebola_NP PF05505.12 ORY03983.1 - 3.6 5.8 8.5 4.3 5.5 8.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4551 PF15087.6 ORY03983.1 - 5 5.8 8.5 5 5.8 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SAPS PF04499.15 ORY03983.1 - 5.4 5.7 7.8 6.1 5.5 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 ORY03983.1 - 9.1 4.9 13.2 10 4.8 13.2 1.0 1 0 0 1 1 1 0 Presenilin Ribosomal_L5_C PF00673.21 ORY03984.1 - 9.4e-23 80.2 0.0 1.4e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY03984.1 - 3.1e-22 78.7 0.0 1.9e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Zona_pellucida PF00100.23 ORY03984.1 - 0.038 13.8 0.0 0.055 13.3 0.0 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain HTH_ABP1_N PF18107.1 ORY03984.1 - 0.12 12.1 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain AAA_2 PF07724.14 ORY03985.1 - 1.6e-41 142.3 0.0 3.2e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ORY03985.1 - 1.2e-15 58.1 0.1 2.8e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY03985.1 - 6.8e-14 51.7 0.1 1.5e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY03985.1 - 1.2e-06 28.5 0.0 4.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY03985.1 - 1.9e-05 24.2 0.3 0.013 14.9 0.1 3.2 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 ORY03985.1 - 0.00062 18.9 0.1 0.012 14.7 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 ORY03985.1 - 0.00064 19.5 1.3 0.02 14.6 0.1 2.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ORY03985.1 - 0.00065 19.5 0.1 0.5 10.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 ORY03985.1 - 0.0012 19.2 0.3 0.0047 17.3 0.2 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY03985.1 - 0.002 18.4 1.8 0.036 14.3 0.4 3.1 3 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 ORY03985.1 - 0.0023 17.4 0.1 0.0055 16.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORY03985.1 - 0.0027 17.1 0.1 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.6 ORY03985.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ORY03985.1 - 0.0059 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORY03985.1 - 0.0065 16.2 0.3 0.027 14.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 ORY03985.1 - 0.016 15.7 0.0 0.04 14.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 ORY03985.1 - 0.023 14.6 0.0 0.089 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 ORY03985.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 ORY03985.1 - 0.031 14.0 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.11 ORY03985.1 - 0.037 13.9 0.1 0.1 12.4 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY03985.1 - 0.043 14.0 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY03985.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SRPRB PF09439.10 ORY03985.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DEAD PF00270.29 ORY03985.1 - 0.15 11.8 0.5 0.66 9.7 0.5 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY03985.1 - 0.15 12.3 0.3 0.87 9.9 0.3 2.2 1 1 0 1 1 1 0 AAA domain GTP_cyclohydro2 PF00925.20 ORY03986.1 - 2.8e-69 231.9 0.0 3.9e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II ComX PF05952.12 ORY03986.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Aminotran_5 PF00266.19 ORY03987.1 - 3.1e-91 306.1 0.0 3.6e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY03987.1 - 1.3e-08 34.5 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY03987.1 - 1.2e-06 28.1 0.1 3e-06 26.8 0.2 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 ORY03987.1 - 0.0007 18.4 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 ORY03987.1 - 0.01 14.4 0.1 0.015 13.9 0.1 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Rad60-SLD PF11976.8 ORY03988.1 - 5.1e-23 80.7 0.1 2.8e-18 65.5 0.5 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY03988.1 - 1.3e-06 28.1 0.1 0.00031 20.4 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin family Par3_HAL_N_term PF12053.8 ORY03988.1 - 0.036 14.3 0.3 0.091 13.0 0.3 1.7 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Glyco_transf_41 PF13844.6 ORY03989.1 - 7.5e-119 397.2 0.2 3.8e-57 193.8 0.0 4.1 3 1 0 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 ORY03989.1 - 5.3e-12 45.0 0.0 3.1e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY03989.1 - 1.2e-10 40.7 0.0 3.1e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY03989.1 - 3.4e-09 36.3 0.3 0.00018 21.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY03989.1 - 2.8e-08 33.3 0.0 0.0046 17.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY03989.1 - 1.7e-07 30.8 0.0 0.0009 18.9 0.0 2.8 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 ORY03989.1 - 5.5e-07 29.5 0.0 0.077 13.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY03989.1 - 6.4e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY03989.1 - 7.5e-06 26.1 0.0 0.032 14.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY03989.1 - 0.0001 22.1 0.0 0.031 14.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY03989.1 - 0.00017 22.0 0.0 0.012 16.1 0.0 2.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY03989.1 - 0.0051 17.5 0.0 0.68 10.9 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY03989.1 - 0.011 15.9 0.1 0.028 14.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF202 PF02656.15 ORY03990.1 - 1.2e-12 48.1 1.2 1.2e-12 48.1 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ArAE_2 PF10334.9 ORY03991.1 - 5.3e-20 72.2 0.1 1.2e-19 71.1 0.1 1.5 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY03991.1 - 3.6e-12 46.5 18.0 6.7e-12 45.6 18.0 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY03991.1 - 7.1e-09 34.8 1.6 8.3e-09 34.5 1.6 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY03991.1 - 0.031 13.1 6.2 0.042 12.7 6.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_L29e PF01779.17 ORY04059.1 - 0.051 13.9 7.2 0.094 13.1 7.2 1.4 1 0 0 1 1 1 0 Ribosomal L29e protein family SRAP PF02586.14 ORY04060.1 - 1.1e-51 175.5 0.1 1.9e-51 174.7 0.1 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) CybS PF05328.12 ORY04061.1 - 2e-35 121.4 0.0 2.9e-35 120.9 0.0 1.3 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Acyl_transf_3 PF01757.22 ORY04061.1 - 0.0048 16.0 0.4 0.0064 15.6 0.4 1.1 1 0 0 1 1 1 1 Acyltransferase family RCC1 PF00415.18 ORY04062.1 - 1e-26 93.3 12.2 1.1e-07 32.3 0.2 7.2 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY04062.1 - 1.1e-26 92.0 12.7 3.5e-07 29.8 0.3 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 ORY04062.1 - 1.3e-07 31.4 0.2 3.2e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY04062.1 - 0.00022 21.0 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Hira PF07569.11 ORY04062.1 - 0.027 14.2 1.0 19 4.9 0.0 3.6 3 1 1 4 4 4 0 TUP1-like enhancer of split F-box_4 PF15966.5 ORY04062.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 F-box Elongin_A PF06881.11 ORY04062.1 - 0.21 12.1 0.0 0.37 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Clat_adaptor_s PF01217.20 ORY04063.1 - 7.3e-54 181.6 5.1 9e-54 181.3 5.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ANAPC5 PF12862.7 ORY04064.1 - 3e-29 100.9 8.6 4.5e-29 100.4 4.5 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 ORY04064.1 - 2.9e-07 30.9 3.8 0.063 13.8 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY04064.1 - 4.7e-06 26.8 17.2 0.0012 19.1 3.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04064.1 - 9.8e-06 25.3 6.8 0.15 12.2 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY04064.1 - 1.2e-05 25.7 5.3 0.51 11.3 0.0 6.1 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04064.1 - 0.00013 21.8 9.1 0.45 10.7 0.3 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY04064.1 - 0.00014 21.5 4.1 0.43 10.5 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY04064.1 - 0.00063 20.2 3.8 0.59 10.9 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY04064.1 - 0.0022 18.2 14.2 0.0075 16.5 0.2 5.3 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY04064.1 - 0.006 17.1 7.6 3.1 8.7 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat SPOB_a PF14689.6 ORY04064.1 - 0.028 14.1 0.1 1.3 8.8 0.0 3.3 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain NusB PF01029.18 ORY04064.1 - 0.083 13.1 0.4 0.26 11.5 0.1 2.1 2 0 0 2 2 2 0 NusB family TPR_16 PF13432.6 ORY04064.1 - 0.13 12.9 3.6 1.3 9.8 0.8 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY04064.1 - 0.2 12.1 4.4 16 6.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04064.1 - 0.75 9.8 6.5 3.4 7.7 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY04064.1 - 7.8 6.6 10.0 0.59 10.2 1.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat START PF01852.19 ORY04065.1 - 1.4e-31 109.5 0.0 1.6e-14 53.8 0.0 3.4 3 0 0 3 3 3 3 START domain ERCC4 PF02732.15 ORY04066.1 - 1.3e-25 90.5 0.0 2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 ORY04066.1 - 0.00026 21.3 0.0 0.00089 19.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain SF3b10 PF07189.11 ORY04067.1 - 2.4e-41 139.7 0.1 2.7e-41 139.5 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.9 ORY04067.1 - 0.017 14.2 0.1 0.019 14.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) RRM_1 PF00076.22 ORY04068.1 - 1.4e-19 69.6 1.8 1.5e-19 69.6 0.4 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY04068.1 - 0.062 13.4 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif Q_salvage PF10343.9 ORY04069.1 - 3.5e-29 102.3 0.0 4.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Dynein_attach_N PF15867.5 ORY04069.1 - 0.17 11.9 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus TatD_DNase PF01026.21 ORY04070.1 - 1.3e-47 162.4 0.0 1.4e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 ORY04070.1 - 0.19 11.5 0.0 10 5.8 0.0 2.6 2 1 0 2 2 2 0 Amidohydrolase HMG_box PF00505.19 ORY04071.1 - 2.6e-15 56.6 0.1 4.9e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY04071.1 - 3.1e-06 27.7 0.0 7.9e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 HMG-box domain PEMT PF04191.13 ORY04072.1 - 2.4e-17 63.3 15.0 5.3e-10 39.6 2.2 3.7 3 1 0 3 3 3 2 Phospholipid methyltransferase eIF_4EBP PF05456.11 ORY04073.1 - 2.8e-31 107.8 6.8 4.3e-31 107.2 6.8 1.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) RRM_1 PF00076.22 ORY04074.1 - 3.7e-19 68.3 0.0 5.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY04074.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY04074.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) efThoc1 PF11957.8 ORY04075.1 - 7.8e-110 367.8 8.2 1e-109 367.5 8.2 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor HMG_box_2 PF09011.10 ORY04075.1 - 0.28 11.8 2.9 4.8 7.8 0.3 2.4 2 0 0 2 2 2 0 HMG-box domain Pkinase PF00069.25 ORY04076.1 - 9.2e-64 215.3 0.0 7.2e-63 212.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04076.1 - 4.5e-27 95.0 0.0 1.2e-17 64.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY04076.1 - 1.7e-05 24.3 0.1 0.053 12.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 ORY04076.1 - 0.0062 15.5 0.2 0.15 10.9 0.0 2.1 1 1 1 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY04076.1 - 0.03 13.4 0.2 0.065 12.3 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C2H2 PF00096.26 ORY04077.1 - 9.5e-19 66.7 25.9 3.3e-05 24.1 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY04077.1 - 1.7e-13 50.3 26.8 1.2e-05 25.5 2.1 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY04077.1 - 9.5e-09 35.4 23.8 0.0028 18.4 0.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY04077.1 - 0.00066 19.9 6.8 0.033 14.5 1.5 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORY04077.1 - 0.0041 17.5 5.6 0.66 10.4 0.0 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type QueF PF14489.6 ORY04077.1 - 0.085 13.0 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 QueF-like protein zf-C2H2_aberr PF17017.5 ORY04077.1 - 0.11 12.6 12.9 4.7 7.3 0.3 3.5 1 1 2 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 ORY04077.1 - 0.99 10.1 11.2 1 10.1 0.2 3.8 3 1 1 4 4 4 0 FOXP coiled-coil domain CHORD PF04968.12 ORY04077.1 - 8.8 7.1 13.7 19 6.1 0.8 3.7 2 1 2 4 4 4 0 CHORD Mlh1_C PF16413.5 ORY04078.1 - 1.5e-93 313.1 1.2 2.6e-93 312.3 0.1 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 ORY04078.1 - 3e-34 117.2 0.4 5.8e-34 116.3 0.4 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY04078.1 - 4.2e-13 49.3 0.0 1.2e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY04078.1 - 1.9e-05 25.1 0.0 4.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M57 PF12388.8 ORY04078.1 - 0.13 11.8 0.4 1.1 8.8 0.0 2.4 1 1 1 3 3 3 0 Dual-action HEIGH metallo-peptidase DWNN PF08783.11 ORY04079.1 - 1.1e-33 115.3 0.1 1.9e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ORY04079.1 - 6.5e-11 41.8 5.7 2e-10 40.3 5.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 ORY04079.1 - 1e-05 25.3 11.2 1e-05 25.3 11.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 ORY04079.1 - 3.5e-05 23.7 2.4 7.4e-05 22.6 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 ORY04079.1 - 0.00023 21.2 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.6 ORY04079.1 - 0.0004 20.2 8.6 0.0004 20.2 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY04079.1 - 0.00094 19.1 10.5 0.00094 19.1 10.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY04079.1 - 0.0011 19.2 11.2 0.0011 19.2 11.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY04079.1 - 0.0013 18.6 12.5 0.0028 17.5 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY04079.1 - 0.0053 16.6 4.8 0.0098 15.7 4.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 ORY04079.1 - 0.025 14.6 8.4 0.054 13.5 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Siva PF05458.12 ORY04079.1 - 0.026 14.2 2.0 0.05 13.3 2.0 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-CCHC_3 PF13917.6 ORY04079.1 - 0.083 12.9 0.2 0.24 11.4 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_4 PF15227.6 ORY04079.1 - 2.1 8.6 18.9 0.064 13.4 12.8 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ORY04079.1 - 5.1 7.3 9.3 0.87 9.8 5.0 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 Arf PF00025.21 ORY04080.1 - 1.7e-65 219.8 0.3 2e-65 219.5 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY04080.1 - 4.2e-16 59.2 0.1 5.6e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY04080.1 - 7.5e-14 51.6 0.1 8.1e-14 51.5 0.1 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY04080.1 - 2.7e-13 49.8 0.1 3.3e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY04080.1 - 9.8e-09 35.3 0.1 1.3e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORY04080.1 - 1.7e-08 34.0 0.1 1.7e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY04080.1 - 1.5e-07 31.1 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 ORY04080.1 - 0.0005 19.7 0.5 0.12 12.0 0.1 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 ORY04080.1 - 0.0031 17.1 0.1 0.68 9.4 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 ORY04080.1 - 0.039 14.0 0.1 0.096 12.7 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY04080.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY04080.1 - 0.065 13.7 0.1 0.13 12.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 ORY04080.1 - 0.089 12.3 1.3 1.2 8.7 0.1 2.1 1 1 1 2 2 2 0 Ferrous iron transport protein B RRM_1 PF00076.22 ORY04081.1 - 2.9e-17 62.2 0.0 4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY04081.1 - 0.0071 15.9 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY04081.1 - 0.029 14.5 0.2 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 Limkain b1 F-box_4 PF15966.5 ORY04082.1 - 2e-06 27.7 0.1 3.3e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 F-box Ribosomal_L21p PF00829.21 ORY04083.1 - 2.2e-26 92.0 1.3 3.1e-26 91.6 1.3 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ribosomal_L24 PF17136.4 ORY04084.1 - 9.1e-13 48.4 0.2 3.3e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ORY04084.1 - 2.5e-05 24.1 4.3 4.9e-05 23.1 4.3 1.5 1 0 0 1 1 1 1 KOW motif MazE_antitoxin PF04014.18 ORY04084.1 - 0.013 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin C4bp_oligo PF18453.1 ORY04085.1 - 0.018 15.2 1.2 0.018 15.2 1.2 2.2 1 1 1 2 2 2 0 Oligomerization domain of C4b-binding protein alpha RBD PF02196.15 ORY04085.1 - 0.022 14.8 0.8 0.06 13.4 0.8 1.7 1 1 0 1 1 1 0 Raf-like Ras-binding domain SWIRM-assoc_1 PF16495.5 ORY04085.1 - 3.1 7.8 9.7 2.5 8.1 3.9 2.2 1 1 1 2 2 2 0 SWIRM-associated region 1 CAP PF00188.26 ORY04086.1 - 3.3e-11 44.1 0.1 4.5e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WRKY PF03106.15 ORY04086.1 - 0.055 13.7 0.5 0.13 12.5 0.5 1.6 1 0 0 1 1 1 0 WRKY DNA -binding domain Misat_Tub_SegII PF10644.9 ORY04087.1 - 1.3e-35 122.3 0.1 3.1e-35 121.0 0.1 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY04087.1 - 2.1e-29 102.5 0.7 3.1e-19 69.3 0.3 2.3 2 0 0 2 2 2 2 Tubulin domain Tubulin PF00091.25 ORY04087.1 - 1e-08 35.6 0.0 0.025 14.8 0.0 3.2 3 0 0 3 3 3 3 Tubulin/FtsZ family, GTPase domain THF_DHG_CYH PF00763.23 ORY04088.1 - 2.1e-28 98.9 0.0 3.5e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 ORY04088.1 - 8.7e-14 51.1 0.4 2.3e-10 40.0 0.0 3.0 2 2 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 ORY04088.1 - 0.0026 17.8 0.1 0.033 14.3 0.0 2.6 3 1 0 3 3 3 1 Dipicolinate synthase subunit A N-terminal domain 2-Hacid_dh_C PF02826.19 ORY04088.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Brix PF04427.18 ORY04089.1 - 2.7e-48 164.7 0.0 4.3e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain Tim44 PF04280.15 ORY04090.1 - 0.024 14.7 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Tim44-like domain HOOK PF05622.12 ORY04091.1 - 0.0014 16.9 3.4 0.0037 15.5 0.1 1.8 1 1 1 2 2 2 1 HOOK protein DUF1664 PF07889.12 ORY04091.1 - 0.008 16.2 1.4 1.9 8.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) FliJ PF02050.16 ORY04091.1 - 0.015 15.6 5.0 0.11 12.8 0.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein CHASE3 PF05227.13 ORY04091.1 - 0.019 14.9 0.2 0.052 13.5 0.0 1.8 1 1 1 2 2 2 0 CHASE3 domain Fib_alpha PF08702.10 ORY04091.1 - 0.059 13.6 3.7 0.33 11.1 0.2 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 ORY04091.1 - 0.13 12.6 5.3 0.77 10.2 2.8 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Mito_carr PF00153.27 ORY04092.1 - 4e-61 203.0 5.1 6.9e-22 77.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex24p PF06398.11 ORY04093.1 - 6.8e-23 81.2 12.1 4.4e-22 78.6 12.1 2.1 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin MRAP PF15183.6 ORY04093.1 - 0.092 12.7 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family zf-H2C2_2 PF13465.6 ORY04094.1 - 2.5e-30 103.5 40.2 2.8e-09 37.0 0.8 7.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 ORY04094.1 - 4.3e-21 74.1 45.5 5.9e-06 26.4 1.8 8.1 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY04094.1 - 2.4e-12 46.6 45.6 0.0029 18.3 0.8 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger FOXP-CC PF16159.5 ORY04094.1 - 3e-09 37.4 31.7 0.0067 17.0 0.4 7.0 3 2 4 7 7 7 4 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY04094.1 - 3.5e-07 30.4 19.4 0.0031 17.8 1.5 4.7 1 1 4 5 5 5 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY04094.1 - 5.7e-06 26.5 7.0 0.25 11.7 0.1 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY04094.1 - 1.3e-05 25.4 15.2 0.011 15.8 0.6 4.1 2 1 2 4 4 4 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 ORY04094.1 - 5.4e-05 23.1 20.7 0.52 10.4 0.0 6.7 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.7 ORY04094.1 - 0.0049 17.2 7.2 0.31 11.5 0.5 4.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY04094.1 - 0.012 15.3 5.9 2.9 7.7 0.0 3.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 ORY04094.1 - 0.046 14.0 25.9 0.14 12.4 0.5 5.4 4 2 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 ORY04094.1 - 0.69 10.1 0.0 0.39 10.8 0.3 7.7 6 2 2 8 8 8 0 Zic proteins zinc finger domain Chromo PF00385.24 ORY04094.1 - 1.4 8.8 8.3 8.8 6.3 0.3 4.0 3 1 2 5 5 5 0 Chromo (CHRromatin Organisation MOdifier) domain zf-tcix PF14952.6 ORY04094.1 - 3.3 7.4 11.4 3.3 7.4 0.1 4.8 6 0 0 6 6 6 0 Putative treble-clef, zinc-finger, Zn-binding Zap1_zf2 PF18217.1 ORY04094.1 - 3.9 7.6 24.2 1 9.4 2.0 4.9 5 0 0 5 5 5 0 Zap1 zinc finger 2 Ald_Xan_dh_C2 PF02738.18 ORY04095.1 - 3.8e-202 672.6 0.1 5.2e-202 672.1 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORY04095.1 - 6.1e-50 169.3 0.0 1.2e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 ORY04095.1 - 1.4e-32 112.4 0.2 3.5e-32 111.0 0.2 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ORY04095.1 - 1.5e-30 105.0 0.0 3.4e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 ORY04095.1 - 2.5e-26 91.8 0.0 8.1e-25 87.0 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 ORY04095.1 - 1.3e-08 34.7 0.2 1.3e-08 34.7 0.2 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 ORY04095.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain E1-E2_ATPase PF00122.20 ORY04096.1 - 1e-44 152.2 0.2 1e-44 152.2 0.2 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY04096.1 - 6.7e-29 100.9 5.9 4.5e-28 98.2 2.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY04096.1 - 2.5e-20 72.3 0.0 4.7e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY04096.1 - 4.6e-17 61.5 0.4 1.3e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 ORY04096.1 - 3.2e-15 57.0 0.0 2.9e-14 53.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY04096.1 - 0.00013 21.8 0.7 0.00065 19.5 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PRiA4_ORF3 PF07929.11 ORY04097.1 - 8.5e-09 35.4 1.8 3e-08 33.5 1.7 1.9 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Pro_CA PF00484.19 ORY04098.1 - 8.4e-49 165.9 0.3 1.2e-48 165.4 0.3 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Gal-bind_lectin PF00337.22 ORY04098.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Galactoside-binding lectin PEMT PF04191.13 ORY04099.1 - 3.1e-34 117.6 4.6 5.7e-34 116.7 4.6 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase tRNA-synt_His PF13393.6 ORY04100.1 - 6.7e-36 124.1 0.0 8.7e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 ORY04100.1 - 6.5e-17 62.1 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY04100.1 - 2e-06 27.8 0.0 4.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Pyr_redox PF00070.27 ORY04100.1 - 0.0081 16.7 0.0 0.5 11.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2d PF01409.20 ORY04100.1 - 0.12 11.9 0.0 14 5.1 0.0 2.4 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) Phosphatase PF15698.5 ORY04100.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatase DUF5521 PF17659.1 ORY04101.1 - 6.1e-36 123.7 0.4 9.2e-36 123.1 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5521) tRNA_anti-codon PF01336.25 ORY04101.1 - 8.8e-09 35.2 0.2 4.9e-07 29.6 0.0 2.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF5088 PF17008.5 ORY04101.1 - 6e-07 29.4 0.1 3.2e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5088) Rep-A_N PF04057.12 ORY04101.1 - 0.016 15.2 1.9 0.022 14.8 0.2 2.1 3 0 0 3 3 3 0 Replication factor-A protein 1, N-terminal domain ADK PF00406.22 ORY04102.1 - 4.6e-12 46.3 4.1 3.3e-10 40.2 4.1 2.9 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY04102.1 - 1.3e-07 32.1 0.0 2.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY04102.1 - 0.15 12.6 0.2 0.64 10.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain TPR_12 PF13424.6 ORY04103.1 - 3.1e-16 59.4 10.5 4e-06 27.0 0.4 5.5 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY04103.1 - 6.9e-13 47.8 12.8 0.0051 16.6 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04103.1 - 1.1e-12 47.1 12.3 0.0071 16.4 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04103.1 - 5.1e-11 41.8 7.4 0.038 14.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04103.1 - 4.4e-09 35.8 13.7 0.066 13.5 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04103.1 - 2.8e-08 33.3 2.6 0.93 9.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY04103.1 - 1.3e-05 25.5 5.7 0.048 14.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY04103.1 - 1.4e-05 24.7 0.1 0.0012 18.3 0.3 2.9 2 1 0 2 2 2 1 MalT-like TPR region MIT PF04212.18 ORY04103.1 - 1.7e-05 24.8 6.4 0.02 14.9 0.1 4.7 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain SNAP PF14938.6 ORY04103.1 - 3.9e-05 23.2 6.0 0.0057 16.1 0.0 3.9 3 1 1 4 4 4 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 ORY04103.1 - 5.3e-05 23.0 4.8 1.4 8.6 0.2 4.2 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_14 PF13428.6 ORY04103.1 - 0.00085 20.0 4.0 59 4.9 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat 14-3-3 PF00244.20 ORY04103.1 - 0.00088 18.8 0.5 0.0023 17.5 0.1 1.9 2 0 0 2 2 2 1 14-3-3 protein TPR_17 PF13431.6 ORY04103.1 - 0.0009 19.5 0.8 9.3 6.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY04103.1 - 0.028 14.7 0.5 7.7 6.8 0.2 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Rapsyn_N PF10579.9 ORY04103.1 - 0.12 12.5 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.6 ORY04103.1 - 0.33 11.6 2.3 40 5.0 0.1 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Bac_globin PF01152.21 ORY04104.1 - 8e-10 38.9 0.0 9.1e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORY04104.1 - 0.0021 18.0 0.3 0.006 16.5 0.1 1.7 1 1 1 2 2 2 1 Protoglobin STE PF02200.16 ORY04105.1 - 0.13 12.6 0.6 0.28 11.6 0.6 1.6 1 1 0 1 1 1 0 STE like transcription factor Sugar_tr PF00083.24 ORY04106.1 - 5.1e-145 483.8 22.1 5.8e-145 483.6 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04106.1 - 8.8e-27 93.9 30.8 1.2e-26 93.5 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tn7_Tnp_TnsA_C PF08721.11 ORY04106.1 - 0.11 13.1 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal Phage_holin_3_2 PF04550.12 ORY04106.1 - 1.1 9.8 6.8 0.2 12.2 1.8 2.4 2 0 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 ORY04107.1 - 2.6e-145 484.7 21.8 3.1e-145 484.5 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04107.1 - 5.5e-27 94.6 30.6 7.5e-27 94.2 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ORY04107.1 - 1.1 9.8 6.8 0.2 12.2 1.8 2.4 2 0 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 ORY04108.1 - 2.6e-145 484.7 21.8 3.1e-145 484.5 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04108.1 - 5.5e-27 94.6 30.6 7.5e-27 94.2 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ORY04108.1 - 1.1 9.8 6.8 0.2 12.2 1.8 2.4 2 0 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 ORY04109.1 - 5.1e-145 483.8 22.1 5.8e-145 483.6 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04109.1 - 8.8e-27 93.9 30.8 1.2e-26 93.5 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tn7_Tnp_TnsA_C PF08721.11 ORY04109.1 - 0.11 13.1 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal Phage_holin_3_2 PF04550.12 ORY04109.1 - 1.1 9.8 6.8 0.2 12.2 1.8 2.4 2 0 0 2 2 2 0 Phage holin family 2 PDH PF02153.17 ORY04153.1 - 1.8e-12 46.8 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 ORY04153.1 - 7.5e-06 26.2 0.0 3.5e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY04153.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ORY04153.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY04153.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ORY04153.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 ORY04153.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 ORY04153.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_8 PF13450.6 ORY04153.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 ORY04154.1 - 2.2e-41 141.7 0.0 4.1e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY04154.1 - 1.3e-12 47.6 11.4 2.2e-12 46.9 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY04154.1 - 2e-05 23.6 0.0 3.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FEZ PF07763.13 ORY04154.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 FEZ-like protein AA_permease_2 PF13520.6 ORY04155.1 - 5.9e-72 242.8 36.2 7.2e-72 242.5 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY04155.1 - 1.5e-25 89.8 29.5 2.3e-25 89.1 29.5 1.2 1 0 0 1 1 1 1 Amino acid permease TMEM101 PF15111.6 ORY04155.1 - 0.00055 19.6 1.1 0.0014 18.2 1.1 1.7 1 0 0 1 1 1 1 TMEM101 protein family zf-C2H2 PF00096.26 ORY04156.1 - 1.7e-19 69.1 29.6 4.1e-06 26.9 0.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY04156.1 - 1.9e-19 69.1 22.3 4.3e-06 26.9 1.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY04156.1 - 4.8e-11 42.5 28.2 0.011 16.5 0.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORY04156.1 - 5.4e-05 23.7 11.2 0.066 13.8 2.3 3.7 2 2 2 4 4 4 3 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORY04156.1 - 0.0036 17.5 10.3 0.5 10.5 0.3 3.3 2 2 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORY04156.1 - 0.013 15.8 8.5 1.5 9.2 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORY04156.1 - 0.015 16.0 2.0 0.015 16.0 2.0 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 ORY04156.1 - 0.018 15.3 13.5 0.65 10.3 6.8 3.0 1 1 3 4 4 4 0 C2H2-type zinc ribbon Phosphoesterase PF04185.14 ORY04156.1 - 0.079 12.1 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoesterase family zf-H2C2_5 PF13909.6 ORY04156.1 - 3.2 7.6 19.7 2.6 7.9 0.2 5.0 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Rhodanese PF00581.20 ORY04157.1 - 7.7e-14 52.1 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Cyclin_N PF00134.23 ORY04159.1 - 5.2e-10 39.2 0.1 6.8e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY04159.1 - 0.00061 20.2 0.0 0.00086 19.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin PPI_Ypi1 PF07491.11 ORY04159.1 - 0.14 12.0 0.6 0.24 11.3 0.6 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor TPR_2 PF07719.17 ORY04160.1 - 9.6e-15 53.4 0.1 5.4e-07 29.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY04160.1 - 2.5e-13 49.2 0.1 4.3e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Lactamase_B PF00753.27 ORY04160.1 - 2.6e-13 50.4 0.7 1.2e-12 48.2 0.7 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_8 PF13181.6 ORY04160.1 - 8.4e-11 41.2 0.2 2.4e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04160.1 - 1.6e-08 34.0 0.0 0.0035 17.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY04160.1 - 7.6e-07 28.7 0.0 0.075 12.7 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 ORY04160.1 - 3.2e-05 24.4 0.0 0.0025 18.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY04160.1 - 0.00026 21.2 0.0 0.67 10.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY04160.1 - 0.0019 18.8 0.0 0.86 10.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 ORY04160.1 - 0.0026 17.8 0.1 0.15 12.1 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 ORY04160.1 - 0.0027 17.9 0.3 0.35 11.1 0.3 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY04160.1 - 0.0064 17.0 1.5 0.23 12.1 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 ORY04160.1 - 0.016 14.7 0.5 0.053 13.0 0.2 2.1 2 1 0 2 2 2 0 Beta-lactamase superfamily domain TPR_19 PF14559.6 ORY04160.1 - 0.044 14.3 0.0 3.8 8.1 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04160.1 - 0.057 13.3 0.1 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 ORY04160.1 - 0.14 12.3 0.1 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2358 PF10184.9 ORY04161.1 - 0.0021 18.3 0.0 0.0089 16.3 0.0 2.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 ORY04161.1 - 0.021 15.4 0.0 0.039 14.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Rhodanese PF00581.20 ORY04162.1 - 1.3e-14 54.6 0.0 2.1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain PAP_assoc PF03828.19 ORY04163.1 - 9.2e-06 25.8 0.0 2.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 ORY04163.1 - 0.0017 18.4 0.0 0.0081 16.2 0.0 2.1 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 ORY04163.1 - 0.0045 17.3 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain NgoMIV_restric PF09015.10 ORY04163.1 - 0.021 13.9 0.7 0.048 12.8 0.1 1.8 2 0 0 2 2 2 0 NgoMIV restriction enzyme Tir_receptor_C PF07489.11 ORY04163.1 - 2.4 8.1 11.4 8.9 6.2 5.2 2.3 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Ribosomal_S7e PF01251.18 ORY04164.1 - 1.7e-85 285.4 2.6 1.9e-85 285.3 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SIR2 PF02146.17 ORY04165.1 - 5.2e-62 208.9 0.0 6.4e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family YdjO PF14169.6 ORY04165.1 - 0.037 13.8 0.4 0.081 12.7 0.4 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Pkinase PF00069.25 ORY04166.1 - 6.1e-67 225.8 0.0 7.2e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04166.1 - 9.7e-33 113.5 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY04166.1 - 0.0002 20.4 0.0 0.00028 20.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Y_phosphatase2 PF03162.13 ORY04167.1 - 4.1e-53 179.4 0.0 4.8e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY04167.1 - 9.3e-05 22.5 0.0 0.00049 20.1 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY04167.1 - 0.0078 15.8 0.0 0.009 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SulA PF03846.14 ORY04167.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Cell division inhibitor SulA DSPc PF00782.20 ORY04167.1 - 0.097 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4055 PF13264.6 ORY04168.1 - 0.0035 17.5 2.7 1.7 8.8 0.2 5.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4055) Peptidase_S41_N PF11918.8 ORY04168.1 - 0.063 13.5 4.5 0.83 9.9 0.2 5.1 3 0 0 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Gal11_ABD1 PF18535.1 ORY04168.1 - 0.094 12.8 11.0 0.078 13.1 0.9 5.8 4 0 0 4 4 4 0 Gal11 activator-binding domain (ABD1) HTH_Tnp_Tc3_1 PF11427.8 ORY04168.1 - 0.23 11.3 2.1 39 4.2 0.0 4.7 4 0 0 4 4 4 0 Tc3 transposase Mating_N PF12731.7 ORY04168.1 - 0.35 11.0 5.4 0.64 10.2 0.8 4.2 3 0 0 3 3 3 0 Mating-type protein beta 1 FlpD PF02662.16 ORY04168.1 - 4.1 7.4 13.1 6.4 6.8 0.1 5.7 6 0 0 6 6 6 0 Methyl-viologen-reducing hydrogenase, delta subunit NAS PF03059.16 ORY04168.1 - 6.4 6.0 13.6 2 7.7 0.1 6.1 6 0 0 6 6 6 0 Nicotianamine synthase protein OSTMP1 PF09777.9 ORY04169.1 - 0.07 12.5 1.0 0.24 10.8 1.0 1.9 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor HJURP_C PF12347.8 ORY04169.1 - 0.15 12.2 1.1 6.8 6.8 0.0 4.0 4 0 0 4 4 4 0 Holliday junction regulator protein family C-terminal repeat YvrJ PF12841.7 ORY04169.1 - 0.34 10.5 4.0 6 6.5 0.3 5.4 4 0 0 4 4 4 0 YvrJ protein family AlphaC_C PF17480.2 ORY04169.1 - 1.8 8.6 8.3 2.1 8.4 0.0 4.6 5 0 0 5 5 5 0 AlphaC C-terminal Arrestin_N PF00339.29 ORY04170.1 - 1.8e-14 54.0 0.0 4.8e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY04170.1 - 6e-12 46.2 0.5 1.9e-11 44.5 0.4 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY04170.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like HTH_micro PF17007.5 ORY04170.1 - 0.018 13.8 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 HTH-like SQS_PSY PF00494.19 ORY04171.1 - 5.1e-41 140.9 0.0 6.6e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase HLH PF00010.26 ORY04172.1 - 1.2e-18 66.8 1.7 2e-18 66.1 1.7 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.9 ORY04172.1 - 0.43 10.8 2.5 0.9 9.8 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) RGS PF00615.19 ORY04173.1 - 2.4e-13 50.4 0.1 5.4e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain CRPA PF05745.11 ORY04173.1 - 0.14 12.2 0.5 0.28 11.2 0.5 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Actin PF00022.19 ORY04174.1 - 1.2e-150 501.7 0.0 4.1e-150 499.9 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 ORY04174.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Abhydrolase_1 PF00561.20 ORY04175.1 - 0.0025 17.5 0.1 0.46 10.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY04175.1 - 0.12 13.0 0.1 0.16 12.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HATPase_c_3 PF13589.6 ORY04176.1 - 8.9e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY04176.1 - 6.4e-11 42.8 0.0 1.8e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 ORY04176.1 - 6.7e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 ORY04176.1 - 8.8e-05 22.3 1.2 0.00021 21.1 0.0 2.2 3 0 0 3 3 3 1 MutL C terminal dimerisation domain DUF3258 PF11646.8 ORY04176.1 - 0.077 13.1 0.2 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF3258 Cullin_Nedd8 PF10557.9 ORY04176.1 - 0.16 12.0 2.7 0.73 9.9 0.0 2.8 3 0 0 3 3 3 0 Cullin protein neddylation domain FHA PF00498.26 ORY04177.1 - 2.8e-16 59.6 0.0 1.2e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 ORY04177.1 - 1e-10 41.1 7.0 1e-10 41.1 7.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY04177.1 - 2.7e-09 37.2 7.4 5.4e-09 36.3 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY04177.1 - 5.7e-05 22.9 6.9 0.00011 21.9 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY04177.1 - 0.0003 21.0 8.5 0.00066 19.9 8.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY04177.1 - 0.0013 18.6 9.4 0.0025 17.6 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY04177.1 - 0.0034 17.4 3.7 0.0061 16.6 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY04177.1 - 0.0057 16.6 7.6 0.014 15.4 7.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 ORY04177.1 - 0.0088 16.3 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 ORY04177.1 - 0.013 15.4 4.7 0.03 14.2 4.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 ORY04177.1 - 0.1 12.7 9.0 0.24 11.4 9.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Methyltransf_31 PF13847.6 ORY04178.1 - 9.3e-10 38.5 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORY04178.1 - 1.6e-07 31.9 0.0 0.00024 21.7 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY04178.1 - 5.7e-07 30.1 0.0 0.0048 17.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORY04178.1 - 2.1e-05 25.2 0.0 0.14 12.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY04178.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 ORY04178.1 - 0.01 14.9 0.0 0.29 10.2 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Forkhead PF00250.18 ORY04179.1 - 1.5e-35 121.3 0.1 1.6e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 ORY04179.1 - 0.055 13.8 0.2 0.074 13.4 0.2 1.3 1 1 0 1 1 1 0 linker histone H1 and H5 family DUF4777 PF16007.5 ORY04179.1 - 0.096 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Hap4_Hap_bind PF10297.9 ORY04180.1 - 0.01 15.9 0.4 0.039 14.1 0.4 2.0 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 UIM PF02809.20 ORY04180.1 - 0.016 15.1 0.2 0.016 15.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif CHAP PF05257.16 ORY04181.1 - 4.3e-12 46.4 0.5 6.2e-12 45.9 0.5 1.2 1 0 0 1 1 1 1 CHAP domain Myb_DNA-binding PF00249.31 ORY04182.1 - 5.2e-30 103.4 6.4 2e-10 40.7 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY04182.1 - 9.2e-25 86.7 5.2 3.8e-10 39.9 0.1 3.2 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY04182.1 - 1.3e-07 31.4 1.0 0.037 13.9 0.0 3.1 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 ORY04182.1 - 8.2e-06 25.9 1.8 0.023 14.9 0.1 2.6 1 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 ORY04182.1 - 7.5e-05 22.7 0.3 0.24 11.4 0.0 3.1 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 ORY04182.1 - 0.0081 16.2 4.1 0.16 12.1 4.1 2.6 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Swm2 PF17083.5 ORY04182.1 - 0.082 12.9 0.8 0.74 9.8 0.1 2.1 2 0 0 2 2 2 0 Nucleolar protein Swm2 Myb_DNA-bind_5 PF13873.6 ORY04182.1 - 0.95 9.6 11.1 11 6.2 0.0 4.3 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY04182.1 - 1.7 9.1 9.2 2.6 8.5 1.8 3.3 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain CHAP PF05257.16 ORY04183.1 - 2e-10 41.1 0.4 5.5e-10 39.7 0.4 1.7 1 0 0 1 1 1 1 CHAP domain SARAF PF06682.12 ORY04183.1 - 2 8.0 16.3 3.1 7.4 16.3 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CHAP PF05257.16 ORY04184.1 - 1.6e-09 38.2 3.0 1.6e-09 38.2 3.0 2.1 1 1 1 2 2 2 1 CHAP domain SURF6 PF04935.12 ORY04185.1 - 7.8e-37 127.0 50.3 7.8e-37 127.0 50.3 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 ORY04185.1 - 2.1e-18 66.6 6.9 2.1e-18 66.6 6.9 5.6 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 DUF1054 PF06335.12 ORY04185.1 - 0.011 15.7 2.1 0.011 15.7 2.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1054) Pkinase PF00069.25 ORY04186.1 - 1.2e-75 254.3 0.0 1.4e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04186.1 - 3.1e-29 102.0 0.0 5.3e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY04186.1 - 0.0072 15.7 0.3 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY04186.1 - 0.018 15.0 0.2 0.042 13.8 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY04186.1 - 0.049 12.6 0.1 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain SIR2 PF02146.17 ORY04187.1 - 2.1 8.2 4.2 3.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Sir2 family Response_reg PF00072.24 ORY04188.1 - 1.1e-52 177.0 0.3 1.3e-25 89.7 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORY04188.1 - 1.4e-52 176.9 0.5 7.4e-25 87.6 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY04188.1 - 4.5e-25 87.5 1.2 1e-15 57.5 0.2 3.1 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ORY04188.1 - 2.4e-08 34.4 0.0 9.1e-06 26.0 0.0 2.8 1 1 1 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 ORY04188.1 - 1.6e-06 28.0 0.1 0.037 13.9 0.1 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ORY04188.1 - 1.3e-05 25.2 0.1 0.00025 21.0 0.0 2.8 2 1 1 3 3 3 1 PAS fold GAF_3 PF13492.6 ORY04188.1 - 5.7e-05 23.5 0.0 0.0063 16.9 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS_4 PF08448.10 ORY04188.1 - 0.0017 18.6 0.0 5.6 7.3 0.0 3.5 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ORY04188.1 - 0.011 15.7 0.0 0.038 14.0 0.0 1.9 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 ORY04188.1 - 0.059 13.7 0.1 0.22 11.8 0.1 2.0 1 0 0 1 1 1 0 PAS fold PhoU PF01895.19 ORY04188.1 - 0.076 13.5 0.4 0.41 11.1 0.4 2.4 1 0 0 1 1 1 0 PhoU domain Phage_int_SAM_1 PF02899.17 ORY04188.1 - 0.11 12.8 0.1 0.49 10.7 0.1 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3472 PF11958.8 ORY04200.1 - 1.3e-11 45.2 0.6 2.2e-11 44.5 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORY04200.1 - 1.8e-06 28.3 13.7 4.1e-06 27.2 13.7 1.6 1 0 0 1 1 1 1 Chitin recognition protein RasGAP PF00616.19 ORY04201.1 - 1.8e-31 109.5 0.6 1.1e-19 71.0 0.0 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 ORY04201.1 - 4.6e-19 69.0 0.0 1.5e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_mid PF14228.6 ORY04201.1 - 5e-05 21.2 0.2 0.00016 19.5 0.2 1.7 1 1 0 1 1 1 1 Cell morphogenesis central region CRAL_TRIO PF00650.20 ORY04201.1 - 0.0021 17.8 0.1 0.0079 15.9 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.22 ORY04201.1 - 0.0023 18.0 1.0 7.6 7.1 0.2 4.6 3 0 0 3 3 3 1 HEAT repeat Rad21_Rec8 PF04824.16 ORY04201.1 - 0.0082 15.4 0.0 0.032 13.5 0.0 2.0 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF2431 PF10354.9 ORY04201.1 - 0.11 12.8 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) STIMATE PF12400.8 ORY04202.1 - 5.6e-20 72.1 2.8 1.1e-19 71.3 2.8 1.4 1 0 0 1 1 1 1 STIMATE family GATA PF00320.27 ORY04203.1 - 6.9e-31 105.6 14.9 3.5e-16 58.5 3.2 2.3 2 0 0 2 2 2 2 GATA zinc finger Vps36-NZF-N PF16988.5 ORY04203.1 - 0.0003 20.1 3.4 0.13 11.7 0.4 3.2 3 1 0 3 3 3 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn-ribbon_8 PF09723.10 ORY04203.1 - 0.00077 19.5 2.2 0.45 10.7 0.2 2.5 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORY04203.1 - 0.0017 17.8 4.9 0.41 10.2 0.5 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding TDP43_N PF18694.1 ORY04203.1 - 0.0047 16.7 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain Cytochrom_c3_2 PF14537.6 ORY04203.1 - 0.016 15.7 5.3 0.024 15.1 4.8 1.6 1 1 0 1 1 1 0 Cytochrome c3 DZR PF12773.7 ORY04203.1 - 0.03 14.3 10.2 1.7 8.7 11.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon zf-C2H2_3 PF13878.6 ORY04203.1 - 0.035 13.9 2.4 11 5.9 0.0 3.3 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Auto_anti-p27 PF06677.12 ORY04203.1 - 0.05 13.8 8.2 0.78 9.9 1.3 2.7 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rpr2 PF04032.16 ORY04203.1 - 0.15 12.3 5.3 15 5.9 3.8 3.3 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain eIF-5_eIF-2B PF01873.17 ORY04203.1 - 0.18 11.7 4.7 1.5 8.8 0.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2387 PF09526.10 ORY04203.1 - 0.43 10.8 6.1 7.8 6.7 0.6 3.1 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) NMD3 PF04981.13 ORY04203.1 - 0.64 9.4 5.0 1.3 8.5 0.3 2.1 1 1 0 2 2 2 0 NMD3 family zn-ribbon_14 PF16503.5 ORY04203.1 - 0.81 9.2 3.9 5.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Zinc-ribbon OrfB_Zn_ribbon PF07282.11 ORY04203.1 - 1.8 8.5 9.2 3.9 7.5 0.2 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Ribosomal_L32p PF01783.23 ORY04203.1 - 3.7 7.9 16.0 0.56 10.5 0.4 4.6 5 0 0 5 5 5 0 Ribosomal L32p protein family zf-B_box PF00643.24 ORY04203.1 - 3.9 7.7 12.3 6 7.1 1.8 3.6 3 1 1 4 4 4 0 B-box zinc finger DUF5572 PF17733.1 ORY04204.1 - 6.4e-23 80.3 3.2 1e-22 79.7 3.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF2334 PF10096.9 ORY04204.1 - 0.066 12.9 0.2 0.37 10.4 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4003 PF13170.6 ORY04204.1 - 0.081 12.3 0.5 0.1 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) ThiF PF00899.21 ORY04205.1 - 1.7e-111 371.4 0.0 3.5e-72 242.7 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 ORY04205.1 - 3.5e-94 315.4 0.2 5.1e-94 314.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ORY04205.1 - 5.9e-36 123.1 0.1 1.4e-35 121.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 ORY04205.1 - 2.6e-35 120.4 0.4 9.6e-35 118.6 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ORY04205.1 - 4.5e-24 84.4 0.1 1.5e-23 82.7 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 ORY04205.1 - 0.12 12.4 0.2 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CWC25 PF12542.8 ORY04206.1 - 2.4e-22 79.8 0.2 2.4e-22 79.8 0.2 4.4 5 0 0 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.9 ORY04206.1 - 6.9e-16 58.2 11.2 6.9e-16 58.2 11.2 5.4 4 3 2 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Ribosomal_S8 PF00410.19 ORY04207.1 - 6.4e-23 81.1 0.1 1.1e-22 80.3 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 GN3L_Grn1 PF08701.11 ORY04208.1 - 4.8e-21 74.6 20.6 9e-21 73.8 20.6 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase RNB PF00773.19 ORY04209.1 - 7.9e-102 340.9 0.1 1.4e-101 340.1 0.1 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY04209.1 - 1.2e-20 73.3 0.0 2.9e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 ORY04209.1 - 2e-17 63.3 0.3 1.6e-16 60.3 0.3 2.4 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 ORY04209.1 - 2.2e-15 56.3 0.0 6.3e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 S1 domain PIN_4 PF13638.6 ORY04209.1 - 2.8e-15 56.8 0.5 8.4e-15 55.2 0.5 1.9 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 ORY04209.1 - 2.8e-10 40.2 0.6 8.2e-07 29.1 0.0 3.8 2 1 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 ORY04209.1 - 0.0027 18.0 1.8 0.0057 17.0 0.0 2.4 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal DUF768 PF05589.11 ORY04209.1 - 0.095 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF768) OB_RNB PF08206.11 ORY04209.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Sld5 PF05916.11 ORY04210.1 - 5.2e-07 30.1 0.4 2.4e-06 28.0 0.2 1.9 2 0 0 2 2 2 1 GINS complex protein Glyco_hydro_20 PF00728.22 ORY04211.1 - 1.1e-96 324.4 5.7 1.3e-96 324.1 5.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04211.1 - 1.3e-20 74.4 0.0 4.9e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04211.1 - 0.00057 20.7 0.0 0.0033 18.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY04212.1 - 5.3e-95 318.8 5.6 6.5e-95 318.5 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04212.1 - 1.9e-20 73.9 0.0 7.3e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04212.1 - 0.00016 22.5 0.0 0.00072 20.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY04213.1 - 2.6e-92 309.9 5.2 3.2e-92 309.6 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04213.1 - 2.9e-20 73.3 0.0 7e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04213.1 - 0.00016 22.5 0.0 0.00069 20.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY04214.1 - 4.7e-94 315.7 5.3 5.7e-94 315.4 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04214.1 - 2e-20 73.8 0.0 7e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04214.1 - 0.00017 22.4 0.0 0.00073 20.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY04215.1 - 1.1e-96 324.4 5.9 1.3e-96 324.1 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04215.1 - 2.6e-20 73.5 0.0 1e-19 71.6 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04215.1 - 0.00013 22.8 0.0 0.00075 20.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY04216.1 - 2.2e-96 323.3 5.8 2.7e-96 323.0 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04216.1 - 5.2e-20 72.5 0.0 2e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04216.1 - 0.00018 22.3 0.0 0.00098 19.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 ORY04217.1 - 2.2e-94 316.8 5.5 2.7e-94 316.5 5.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY04217.1 - 2.2e-20 73.7 0.0 7.4e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY04217.1 - 0.00018 22.3 0.0 0.00077 20.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sugar_tr PF00083.24 ORY04218.1 - 7.1e-82 275.7 29.9 4.9e-81 272.9 29.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04218.1 - 1e-23 83.9 30.5 1e-23 83.9 30.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY04218.1 - 0.16 10.4 14.1 0.26 9.6 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Fz PF01392.22 ORY04219.1 - 0.0062 17.2 1.1 0.0099 16.5 1.1 1.4 1 1 0 1 1 1 1 Fz domain Pkinase PF00069.25 ORY04221.1 - 8.4e-62 208.9 0.0 1.1e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04221.1 - 4.9e-34 117.8 0.0 6.8e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY04221.1 - 6e-06 25.8 0.0 8.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY04221.1 - 2.2e-05 23.9 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY04221.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY04221.1 - 0.00011 21.3 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY04221.1 - 0.0066 16.1 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 ORY04221.1 - 0.053 13.1 0.1 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 ORY04221.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Acetyltransf_1 PF00583.25 ORY04222.1 - 2.4e-17 63.3 0.0 3e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY04222.1 - 3.1e-13 49.8 0.0 3.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY04222.1 - 2.8e-11 43.7 0.0 3.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY04222.1 - 2.1e-06 27.6 0.1 3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY04222.1 - 2.9e-05 24.2 0.0 3.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY04222.1 - 4.6e-05 23.6 0.2 5.8e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY04222.1 - 0.00031 20.4 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY04222.1 - 0.0024 18.6 0.0 0.0028 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY04222.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M13_N PF05649.13 ORY04223.1 - 1.3e-87 295.0 0.0 1.8e-87 294.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY04223.1 - 6.4e-67 225.1 0.1 1e-66 224.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 ORY04223.1 - 0.05 13.4 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 DUF3470 PF11953.8 ORY04223.1 - 0.33 10.9 2.2 0.99 9.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3470) Mem_trans PF03547.18 ORY04224.1 - 7.1e-47 159.6 16.5 2.5e-45 154.5 16.5 2.0 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 ORY04225.1 - 6.7e-27 94.5 0.0 8.1e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04225.1 - 1.9e-12 47.0 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY04225.1 - 2.1e-06 26.8 0.0 2.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY04225.1 - 0.058 13.3 0.0 5 7.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY04226.1 - 3.9e-73 246.0 0.0 5e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04226.1 - 4.5e-48 163.8 0.0 6.8e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB1 PF18190.1 ORY04226.1 - 2.2e-06 27.8 0.2 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 Pkinase_fungal PF17667.1 ORY04226.1 - 8.4e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY04226.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORY04226.1 - 0.01 15.4 0.3 0.021 14.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 ORY04226.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY04226.1 - 0.034 14.1 0.1 0.2 11.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY04226.1 - 0.085 11.8 0.1 0.15 11.0 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain HrpB1_HrpK PF09613.10 ORY04226.1 - 0.13 11.9 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) IU_nuc_hydro PF01156.19 ORY04227.1 - 1.1e-63 215.6 0.0 1.4e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aa_trans PF01490.18 ORY04228.1 - 2.6e-92 309.6 16.9 3e-92 309.5 16.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY04228.1 - 6.1e-06 25.5 8.5 6.1e-06 25.5 8.5 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family IU_nuc_hydro PF01156.19 ORY04229.1 - 4.8e-62 210.3 0.0 5.8e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Uricase PF01014.18 ORY04230.1 - 1.8e-65 219.1 2.9 8.9e-38 129.5 1.4 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04230.1 - 0.0024 18.4 0.2 0.0054 17.3 0.2 1.6 1 0 0 1 1 1 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04231.1 - 3.2e-67 224.7 3.0 2e-36 125.1 1.2 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04231.1 - 0.033 14.7 0.9 0.091 13.3 0.2 2.0 2 0 0 2 2 2 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY04232.1 - 5.6e-62 207.8 3.0 2.3e-37 128.2 1.2 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04232.1 - 0.0005 20.6 0.2 0.0059 17.1 0.1 2.2 2 0 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04233.1 - 3.2e-67 224.7 3.0 2e-36 125.1 1.2 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04233.1 - 0.033 14.7 0.9 0.091 13.3 0.2 2.0 2 0 0 2 2 2 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY04234.1 - 6e-63 210.9 2.5 7.9e-38 129.7 1.1 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04234.1 - 0.00093 19.7 0.2 0.011 16.2 0.1 2.2 2 0 0 2 2 2 1 Dihydroneopterin aldolase CIAPIN1 PF05093.13 ORY04235.1 - 3.6e-22 78.8 15.7 4.6e-18 65.6 3.2 2.7 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CRM1_C PF08767.11 ORY04236.1 - 2.4e-134 447.6 4.8 4.7e-134 446.6 0.1 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 ORY04236.1 - 3.6e-41 140.7 4.2 3.6e-41 140.7 4.2 4.4 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ORY04236.1 - 6.9e-35 118.5 4.5 1.9e-34 117.1 4.5 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 ORY04236.1 - 1.1e-29 102.3 4.4 1.8e-29 101.6 2.6 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ORY04236.1 - 4.8e-22 77.2 1.2 1.6e-21 75.5 1.2 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 ORY04236.1 - 2.3e-13 49.8 0.1 1.1e-12 47.6 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 ORY04236.1 - 0.00068 19.6 1.6 0.065 13.1 0.0 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) LIM_bind PF01803.16 ORY04236.1 - 0.0081 15.7 0.0 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 LIM-domain binding protein BID PF06393.11 ORY04236.1 - 0.033 13.7 0.5 0.15 11.6 0.0 2.4 3 1 1 4 4 4 0 BH3 interacting domain (BID) Orthopox_A49R PF06489.11 ORY04236.1 - 0.035 14.3 0.5 12 6.1 0.0 3.1 3 0 0 3 3 2 0 Orthopoxvirus A49R protein Symplekin_C PF12295.8 ORY04236.1 - 0.042 13.9 0.7 1.7 8.7 0.0 3.5 3 1 0 3 3 3 0 Symplekin tight junction protein C terminal MMS19_C PF12460.8 ORY04236.1 - 0.049 12.7 4.6 0.7 8.9 0.0 3.8 3 2 1 4 4 4 0 RNAPII transcription regulator C-terminal Pre-PUA PF17832.1 ORY04236.1 - 0.16 12.7 0.3 38 5.1 0.0 3.7 3 0 0 3 3 3 0 Pre-PUA-like domain Vac14_Fab1_bd PF12755.7 ORY04236.1 - 2.4 8.8 6.9 7.5 7.2 0.1 4.7 6 0 0 6 6 5 0 Vacuolar 14 Fab1-binding region Ras PF00071.22 ORY04237.1 - 3.1e-65 218.7 0.9 3.7e-65 218.5 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY04237.1 - 8.7e-37 126.0 0.1 1.5e-36 125.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY04237.1 - 1.7e-17 63.4 0.1 2.1e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY04237.1 - 4.5e-06 26.7 0.8 0.083 12.8 0.3 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORY04237.1 - 7.9e-06 25.5 0.4 1.9e-05 24.3 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY04237.1 - 1.2e-05 24.8 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY04237.1 - 2e-05 24.1 0.1 3.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY04237.1 - 3.5e-05 23.8 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY04237.1 - 0.00092 18.8 0.0 0.0057 16.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 ORY04237.1 - 0.0028 17.2 0.2 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORY04237.1 - 0.007 16.8 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY04237.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY04237.1 - 0.029 14.8 0.0 0.25 11.8 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY04237.1 - 0.04 14.4 0.1 0.077 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF3873 PF12989.7 ORY04237.1 - 0.041 14.3 0.1 0.095 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Septin PF00735.18 ORY04237.1 - 0.046 13.0 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 ORY04237.1 - 0.046 14.0 0.0 0.064 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORY04237.1 - 0.051 13.3 0.1 1.1 9.0 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ORY04237.1 - 0.055 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORY04237.1 - 0.064 12.7 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Uricase PF01014.18 ORY04238.1 - 5.6e-54 181.9 2.5 6.5e-27 94.4 0.8 2.1 2 0 0 2 2 2 2 Uricase FidL_like PF15941.5 ORY04238.1 - 0.58 10.6 2.6 5.8 7.4 0.2 2.3 2 0 0 2 2 2 0 FidL-like putative membrane protein Uricase PF01014.18 ORY04239.1 - 1.1e-53 181.0 3.2 1.9e-29 102.6 1.3 2.1 2 0 0 2 2 2 2 Uricase Uricase PF01014.18 ORY04240.1 - 5.6e-63 211.0 3.2 4.7e-36 123.9 1.2 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04240.1 - 0.059 13.9 0.1 0.19 12.3 0.1 1.8 1 1 0 1 1 1 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY04241.1 - 6.6e-61 204.3 5.5 5.4e-36 123.7 3.3 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04241.1 - 0.00037 21.0 1.2 0.0039 17.7 0.5 2.3 2 1 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04242.1 - 6.4e-59 197.9 1.4 1.2e-31 109.6 0.3 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04242.1 - 0.069 13.7 0.2 0.18 12.3 0.2 1.7 1 0 0 1 1 1 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY04243.1 - 7e-61 204.3 5.3 2e-36 125.1 3.0 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04243.1 - 0.00023 21.7 0.8 0.0027 18.2 0.5 2.3 2 1 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04244.1 - 5.5e-63 211.1 3.2 4.7e-36 123.9 1.2 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04244.1 - 0.071 13.7 0.3 0.2 12.2 0.3 1.8 1 0 0 1 1 1 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY04245.1 - 3.9e-54 182.4 5.6 5e-36 123.9 3.3 2.3 2 1 0 2 2 2 2 Uricase FolB PF02152.18 ORY04245.1 - 0.0016 19.0 0.9 0.0042 17.6 0.8 1.8 2 0 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04246.1 - 5.4e-63 211.1 3.2 4.7e-36 123.9 1.2 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04246.1 - 0.071 13.7 0.3 0.2 12.2 0.3 1.8 1 0 0 1 1 1 0 Dihydroneopterin aldolase Uricase PF01014.18 ORY04247.1 - 1.8e-60 202.9 5.5 5.4e-36 123.7 3.3 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04247.1 - 0.00039 20.9 1.2 0.0044 17.5 0.8 2.3 2 0 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04248.1 - 1.7e-53 180.4 4.7 8.6e-33 113.4 2.5 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 ORY04248.1 - 0.00023 21.7 0.3 0.0022 18.5 0.4 2.1 2 0 0 2 2 2 1 Dihydroneopterin aldolase Uricase PF01014.18 ORY04249.1 - 1.3e-05 25.5 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Uricase zf-H2C2_2 PF13465.6 ORY04250.1 - 2.4e-11 43.5 5.0 1.3e-08 34.9 0.7 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY04250.1 - 1.2e-06 28.7 10.6 8.4e-06 26.0 3.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY04250.1 - 4.3e-06 27.1 8.7 0.00012 22.6 2.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY04250.1 - 0.064 13.3 6.8 0.26 11.3 1.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY04250.1 - 0.067 13.0 3.7 0.13 12.0 0.4 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_4 PF07975.12 ORY04250.1 - 0.13 12.5 5.8 2.7 8.3 5.9 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 ORY04250.1 - 0.77 9.7 6.0 1.5 8.8 1.3 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 ORY04250.1 - 0.77 9.4 5.7 0.32 10.6 0.9 2.0 1 1 1 2 2 2 0 MYST family zinc finger domain Velvet PF11754.8 ORY04251.1 - 7.4e-59 199.7 0.0 1.5e-34 120.1 0.0 2.0 1 1 1 2 2 2 2 Velvet factor DUF3472 PF11958.8 ORY04252.1 - 5.8e-13 49.7 0.9 1.1e-12 48.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Chitin_bind_1 PF00187.19 ORY04252.1 - 2.7e-07 31.0 14.3 6.3e-07 29.8 14.3 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF5077 PF16871.5 ORY04252.1 - 0.017 15.0 0.3 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) MFS_1 PF07690.16 ORY04303.1 - 1.7e-32 112.7 38.2 7.3e-26 90.9 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY04303.1 - 1.4e-11 43.9 4.4 1.4e-11 43.9 4.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY04303.1 - 2e-07 29.8 0.5 4e-07 28.8 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY04303.1 - 0.0051 15.3 0.7 0.024 13.0 0.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector ABC_tran PF00005.27 ORY04304.1 - 1.3e-44 152.0 1.0 4.3e-20 72.6 0.0 3.4 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.6 ORY04304.1 - 3.6e-14 53.3 18.9 6.1e-05 23.0 0.4 4.2 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY04304.1 - 4.3e-10 39.4 6.4 0.015 14.7 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY04304.1 - 2.5e-07 30.3 2.9 0.00039 20.1 0.2 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY04304.1 - 8.7e-05 22.8 1.0 0.1 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORY04304.1 - 0.00021 21.3 0.4 0.058 13.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY04304.1 - 0.0009 19.8 4.7 0.41 11.1 0.2 2.5 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORY04304.1 - 0.0017 18.4 0.5 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY04304.1 - 0.0021 18.0 3.6 0.29 11.0 0.3 2.9 3 0 0 3 3 3 2 RsgA GTPase NACHT PF05729.12 ORY04304.1 - 0.0033 17.3 0.1 1.8 8.5 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_24 PF13479.6 ORY04304.1 - 0.0041 16.9 0.3 1.1 9.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ORY04304.1 - 0.0044 16.8 8.4 0.91 9.2 0.5 3.4 3 0 0 3 3 3 2 AAA ATPase domain MeaB PF03308.16 ORY04304.1 - 0.01 14.8 1.7 0.46 9.4 0.2 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ORY04304.1 - 0.012 16.0 1.2 2.3 8.6 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ORY04304.1 - 0.026 14.7 0.0 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY04304.1 - 0.035 13.3 3.3 7.5 5.7 0.4 3.4 3 1 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.14 ORY04304.1 - 0.051 13.6 0.9 23 5.0 0.1 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY04304.1 - 0.1 13.0 0.9 16 6.0 0.2 2.8 2 1 0 2 2 2 0 RNA helicase Apo-CII PF05355.11 ORY04304.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C-II AAA_28 PF13521.6 ORY04304.1 - 0.15 12.3 0.8 14 5.9 0.2 2.8 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 ORY04304.1 - 0.23 11.3 0.3 6.2 6.7 0.0 2.5 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 ORY04304.1 - 0.27 10.8 1.7 12 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 ORY04304.1 - 0.83 8.8 6.7 17 4.5 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF815) ABC_tran_Xtn PF12848.7 ORY04304.1 - 1.5 8.9 4.3 14 5.8 0.2 2.7 2 1 1 3 3 2 0 ABC transporter NTPase_1 PF03266.15 ORY04304.1 - 1.7 8.5 3.8 25 4.7 0.2 2.9 3 0 0 3 3 3 0 NTPase DUF87 PF01935.17 ORY04304.1 - 4.9 7.2 7.2 11 6.0 0.6 2.7 2 1 1 3 3 3 0 Helicase HerA, central domain APH PF01636.23 ORY04305.1 - 1.8e-08 34.6 0.9 2.8e-08 34.0 0.9 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY04305.1 - 2.2e-07 30.5 0.0 1.8e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 ORY04305.1 - 2.1e-05 23.6 0.1 6.7e-05 21.9 0.1 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1679) Trp_syntA PF00290.20 ORY04306.1 - 3e-85 285.2 0.0 6e-85 284.2 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 ORY04306.1 - 1.2e-48 166.0 0.3 1.9e-48 165.4 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 ORY04306.1 - 0.015 14.7 0.1 0.049 13.1 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein TMEM51 PF15345.6 ORY04307.1 - 0.0099 15.7 0.1 0.0099 15.7 0.1 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 HemY_N PF07219.13 ORY04307.1 - 0.022 14.9 1.6 0.04 14.1 1.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus m04gp34like PF12216.8 ORY04307.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Immune evasion protein DUF373 PF04123.13 ORY04307.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TMEM223 PF14640.6 ORY04307.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 APH PF01636.23 ORY04308.1 - 9.1e-11 42.1 1.2 1.4e-10 41.5 1.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY04308.1 - 1e-08 34.9 0.0 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 ORY04308.1 - 2.4e-06 26.7 0.0 4.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ORY04308.1 - 0.0039 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Extensin_2 PF04554.13 ORY04312.1 - 0.092 12.8 36.4 0.11 12.6 14.5 2.4 1 1 1 2 2 2 0 Extensin-like region Mucin-like PF16058.5 ORY04312.1 - 5.8 7.1 38.6 55 3.9 38.6 2.0 1 1 0 1 1 1 0 Mucin-like Trypan_PARP PF05887.11 ORY04313.1 - 0.1 12.6 10.1 0.16 11.9 10.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAP PF07174.11 ORY04314.1 - 2.1 7.7 20.3 3 7.2 20.3 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Trypan_PARP PF05887.11 ORY04314.1 - 5 7.1 15.0 2.8 7.9 13.0 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FAP PF07174.11 ORY04316.1 - 0.36 10.3 21.1 0.55 9.6 21.1 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) FAP PF07174.11 ORY04317.1 - 0.55 9.6 16.4 0.48 9.8 14.3 1.8 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Nramp PF01566.18 ORY04321.1 - 1.1e-122 409.4 20.3 1.1e-122 409.4 20.3 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein GDP_Man_Dehyd PF16363.5 ORY04322.1 - 2.1e-57 195.0 0.0 3.1e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY04322.1 - 2.3e-52 177.9 0.2 3.2e-52 177.4 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY04322.1 - 2.6e-15 56.4 0.0 1.6e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY04322.1 - 1.6e-14 53.6 0.1 4.2e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY04322.1 - 8e-11 41.6 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORY04322.1 - 3.5e-08 33.6 0.0 6.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ORY04322.1 - 9.2e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ORY04322.1 - 1.5e-05 25.0 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY04322.1 - 1.7e-05 24.1 0.1 0.035 13.3 0.1 2.4 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ORY04322.1 - 2.9e-05 23.7 0.2 0.0039 16.8 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family Methyltransf_31 PF13847.6 ORY04322.1 - 0.0087 15.9 0.0 0.17 11.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Semialdhyde_dh PF01118.24 ORY04322.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ORY04322.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 ORY04322.1 - 0.1 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY04322.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TP_methylase PF00590.20 ORY04323.1 - 1e-47 162.8 0.0 1.9e-47 161.9 0.0 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORY04323.1 - 2.3e-22 79.4 0.1 5.7e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORY04323.1 - 2.4e-17 62.3 0.2 8e-17 60.6 0.0 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORY04323.1 - 1.2e-07 31.1 0.3 3.8e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central PPS_PS PF02006.16 ORY04323.1 - 0.016 14.8 0.3 0.093 12.3 0.0 2.3 3 0 0 3 3 3 0 Phosphopantothenate/pantothenate synthetase DUF410 PF04190.13 ORY04324.1 - 5.1e-81 272.2 0.1 6.5e-81 271.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 ORY04324.1 - 0.05 13.7 4.8 29 5.1 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04324.1 - 0.09 12.9 0.8 17 5.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04324.1 - 0.46 10.8 4.6 2.9 8.3 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 ORY04325.1 - 2.7e-12 46.8 8.7 3.8e-12 46.3 8.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY04325.1 - 2.3e-08 34.2 7.1 4.6e-08 33.2 7.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY04325.1 - 2.9e-08 33.5 9.0 4.2e-08 32.9 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY04325.1 - 3.7e-08 33.1 8.2 5.5e-08 32.5 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY04325.1 - 2.8e-07 30.4 7.6 4e-07 29.9 7.6 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 ORY04325.1 - 3e-07 30.1 5.0 3e-07 30.1 5.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY04325.1 - 8e-05 22.6 0.9 8e-05 22.6 0.9 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY04325.1 - 0.00029 20.8 4.6 0.00063 19.7 4.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY04325.1 - 0.0004 20.2 6.6 0.00061 19.6 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY04325.1 - 0.00042 19.9 4.8 0.00066 19.3 4.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY04325.1 - 0.018 15.1 10.2 0.032 14.4 10.2 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 ORY04325.1 - 0.029 14.2 6.0 0.053 13.4 6.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 ORY04325.1 - 0.066 13.1 4.3 0.13 12.2 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY04325.1 - 0.44 10.4 8.0 0.99 9.3 8.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 ORY04325.1 - 0.81 9.9 10.0 3.2 8.0 10.1 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 ORY04325.1 - 3.4 8.0 8.3 7 7.1 8.3 1.6 1 1 0 1 1 1 0 RING-like domain Tyrosinase PF00264.20 ORY04326.1 - 2.1e-13 51.1 0.0 4.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase BAR PF03114.18 ORY04327.1 - 2.5e-37 128.8 12.7 3.5e-37 128.3 12.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 ORY04327.1 - 4e-14 52.2 0.2 8.4e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY04327.1 - 5.5e-14 51.5 0.2 1.1e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY04327.1 - 5.3e-12 45.2 0.1 9.1e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 ORY04327.1 - 0.014 15.2 8.3 0.021 14.5 8.3 1.3 1 0 0 1 1 1 0 BAR domain of APPL family Herpes_Helicase PF02689.14 ORY04327.1 - 0.1 10.5 2.4 0.14 10.1 2.4 1.0 1 0 0 1 1 1 0 Helicase DUF1501 PF07394.12 ORY04327.1 - 0.2 10.7 2.8 0.31 10.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) adh_short_C2 PF13561.6 ORY04328.1 - 9.2e-44 149.7 0.4 1.1e-43 149.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY04328.1 - 2.1e-34 118.7 0.8 2.6e-34 118.4 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY04328.1 - 2.4e-08 34.1 0.1 4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY04328.1 - 0.0019 17.7 0.2 0.11 11.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Thiolase_C PF02803.18 ORY04328.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain UNC-93 PF05978.16 ORY04329.1 - 5.4e-07 29.5 11.9 5.4e-07 29.5 11.9 2.8 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY04329.1 - 8.6e-06 24.9 32.8 8.6e-06 24.9 32.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Elf1 PF05129.13 ORY04330.1 - 2.1e-29 101.4 4.4 2.7e-29 101.0 4.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Tyr-DNA_phospho PF06087.12 ORY04331.1 - 1.5e-93 314.0 0.1 1.7e-93 313.9 0.1 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Ras PF00071.22 ORY04332.1 - 1.4e-54 184.0 0.0 1.7e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY04332.1 - 5.7e-22 78.2 0.0 7.9e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY04332.1 - 2.4e-08 33.6 0.0 3.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_L21e PF01157.18 ORY04333.1 - 2.1e-47 159.1 6.8 2.5e-47 158.9 5.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e S4 PF01479.25 ORY04334.1 - 1e-12 47.5 1.0 1e-12 47.5 1.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY04334.1 - 4.1e-05 24.4 0.1 9.1e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SPT_ssu-like PF11779.8 ORY04335.1 - 6.8e-20 70.4 2.3 7.8e-20 70.2 2.3 1.1 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF2362 PF10154.9 ORY04336.1 - 3.3e-53 181.4 16.4 1.8e-31 109.6 0.0 3.3 2 1 1 3 3 3 3 Uncharacterized conserved protein (DUF2362) UBA PF00627.31 ORY04336.1 - 0.00025 20.9 0.1 0.0012 18.7 0.1 2.2 3 0 0 3 3 3 1 UBA/TS-N domain MlaC PF05494.12 ORY04336.1 - 0.014 15.2 0.8 0.026 14.3 0.8 1.4 1 0 0 1 1 1 0 MlaC protein SAM_2 PF07647.17 ORY04337.1 - 1.1e-16 60.7 0.0 1.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 ORY04337.1 - 6.3e-16 58.8 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 ORY04337.1 - 4.8e-15 55.8 0.1 7.8e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY04337.1 - 0.0038 17.4 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_4 PF18017.1 ORY04337.1 - 0.039 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) WD40 PF00400.32 ORY04338.1 - 1.1e-45 152.6 8.5 1.2e-06 29.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04338.1 - 3.4e-13 49.7 0.0 0.31 11.3 0.0 6.6 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 ORY04338.1 - 3.9e-13 48.7 3.1 9.5e-13 47.5 3.1 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 ORY04338.1 - 5.9e-05 22.2 0.0 0.7 8.8 0.0 4.2 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY04338.1 - 0.0011 18.3 0.0 1.6 8.0 0.0 3.5 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 ORY04338.1 - 0.01 14.5 0.2 8 5.0 0.0 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORY04338.1 - 0.087 12.1 0.1 2.3 7.5 0.0 3.0 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal RhoGAP PF00620.27 ORY04339.1 - 8.8e-38 129.5 0.1 2.1e-37 128.3 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY04339.1 - 3.1e-28 97.8 44.2 5.7e-13 48.9 3.0 4.7 5 0 0 5 5 5 4 LIM domain DUF724 PF05266.14 ORY04339.1 - 0.067 13.0 1.4 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATP-synt_ab PF00006.25 ORY04340.1 - 2e-74 249.9 0.0 3.5e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY04340.1 - 5.1e-49 165.8 0.1 9e-49 165.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY04340.1 - 5.1e-20 71.8 1.9 1.5e-19 70.3 1.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ORY04340.1 - 0.052 13.7 1.8 0.79 9.9 1.8 2.5 1 1 0 1 1 1 0 HAS barrel domain ATPase_2 PF01637.18 ORY04340.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMM1 PF10296.9 ORY04341.1 - 5.6e-07 28.9 0.1 1.4e-06 27.7 0.1 1.6 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Cnd3 PF12719.7 ORY04342.1 - 6.5e-76 255.3 7.4 6.5e-76 255.3 7.4 2.8 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 ORY04342.1 - 4.7e-09 36.5 1.4 6.3e-07 29.7 0.2 5.1 5 1 2 7 7 7 2 HEAT repeats HEAT PF02985.22 ORY04342.1 - 6.7e-07 29.0 5.3 0.16 12.3 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 ORY04342.1 - 5.2e-05 23.6 3.6 1.2 9.7 0.3 5.8 5 1 1 6 6 6 1 HEAT-like repeat TIP120 PF08623.10 ORY04342.1 - 0.012 15.4 0.9 0.012 15.4 0.9 4.2 5 1 0 5 5 5 0 TATA-binding protein interacting (TIP20) Nab2 PF11517.8 ORY04342.1 - 0.098 13.0 1.6 55 4.1 0.0 3.6 3 0 0 3 3 3 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) AbiJ_NTD4 PF18863.1 ORY04342.1 - 0.11 12.9 2.8 0.21 12.0 0.3 2.8 4 0 0 4 4 4 0 AbiJ N-terminal domain 4 HTH_16 PF12645.7 ORY04342.1 - 0.95 9.6 3.8 12 6.0 0.0 3.8 3 0 0 3 3 3 0 Helix-turn-helix domain Cnd1 PF12717.7 ORY04342.1 - 1.5 8.8 16.9 0.15 12.1 0.5 5.2 5 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Acyltransferase PF01553.21 ORY04343.1 - 7.7e-28 96.8 0.0 1.2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Sds3 PF08598.11 ORY04344.1 - 3e-17 63.4 10.7 5.7e-17 62.5 8.9 2.0 1 1 1 2 2 2 1 Sds3-like DASH_Dad3 PF08656.10 ORY04344.1 - 0.25 11.4 1.7 12 6.1 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad3 Abhydrolase_1 PF00561.20 ORY04345.1 - 1.3e-22 80.7 0.0 2.6e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY04345.1 - 4.8e-17 63.3 0.0 5.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY04345.1 - 1.6e-12 47.2 0.0 8.7e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORY04345.1 - 3e-08 34.1 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ORY04345.1 - 6.7e-08 32.5 0.2 5.4e-06 26.3 0.2 2.3 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ORY04345.1 - 0.00094 18.8 0.0 0.0019 17.7 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 ORY04345.1 - 0.00097 18.9 0.0 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 ORY04345.1 - 0.0017 18.0 0.0 0.0051 16.3 0.0 1.8 2 1 0 2 2 2 1 Lipase (class 2) Palm_thioest PF02089.15 ORY04345.1 - 0.0029 17.5 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 ORY04345.1 - 0.0042 16.0 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.11 ORY04345.1 - 0.006 16.0 0.1 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 ORY04345.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 ORY04345.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.9 ORY04345.1 - 0.042 12.9 0.0 7.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 ORY04345.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 ORY04345.1 - 0.093 12.4 0.4 0.65 9.6 0.4 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LCAT PF02450.15 ORY04345.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Ribosomal_L50 PF10501.9 ORY04346.1 - 5.4e-08 33.0 4.3 1.3e-07 31.8 4.3 1.7 1 1 0 1 1 1 1 Ribosomal subunit 39S DUF908 PF06012.12 ORY04346.1 - 0.0046 16.4 0.3 0.0058 16.1 0.3 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Glycos_trans_3N PF02885.17 ORY04346.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain RNA_pol_Rpb1_1 PF04997.12 ORY04347.1 - 5.6e-92 308.4 0.0 1e-91 307.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ORY04347.1 - 2.2e-85 286.3 1.1 3.4e-85 285.7 1.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY04347.1 - 5.7e-72 241.4 0.0 1.1e-71 240.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY04347.1 - 1.3e-38 132.5 0.4 6.3e-38 130.2 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY04347.1 - 9.5e-29 99.5 0.0 2.2e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 VASt PF16016.5 ORY04348.1 - 6e-37 127.4 0.2 1.2e-36 126.4 0.2 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORY04348.1 - 5.1e-21 74.7 0.2 1.1e-20 73.6 0.2 1.6 1 0 0 1 1 1 1 GRAM domain GutM PF06923.11 ORY04348.1 - 0.052 13.6 0.1 0.42 10.7 0.1 2.2 2 0 0 2 2 2 0 Glucitol operon activator protein (GutM) WD40 PF00400.32 ORY04349.1 - 1.1e-05 26.0 19.8 0.08 13.9 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat adh_short_C2 PF13561.6 ORY04350.1 - 4.6e-46 157.3 0.4 5.3e-46 157.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY04350.1 - 4.9e-36 124.0 0.8 6.1e-36 123.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY04350.1 - 1.6e-08 34.6 0.1 2.4e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY04350.1 - 0.0042 16.6 0.6 0.22 11.0 0.3 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_C PF02803.18 ORY04350.1 - 0.051 13.2 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain DUF594 PF04578.13 ORY04350.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF594 adh_short_C2 PF13561.6 ORY04395.1 - 3.5e-54 183.8 0.0 4.8e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY04395.1 - 5.3e-46 156.6 0.1 6.8e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY04395.1 - 4.4e-10 39.8 0.1 6.2e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY04395.1 - 0.024 13.8 0.5 0.033 13.3 0.5 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_transf_10 PF00852.19 ORY04396.1 - 3.3e-44 150.7 1.6 5.1e-44 150.1 1.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 ORY04396.1 - 3.2e-08 34.0 0.1 1.8e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal SRP68 PF16969.5 ORY04398.1 - 5.7e-136 454.8 3.9 6.6e-136 454.6 3.9 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 vATP-synt_AC39 PF01992.16 ORY04400.1 - 1.2e-118 396.5 0.4 1.4e-118 396.3 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Chromo_shadow PF01393.19 ORY04402.1 - 9.9e-18 64.0 2.4 1.4e-16 60.3 0.3 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 ORY04402.1 - 9.8e-17 60.6 2.8 9.8e-17 60.6 2.8 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DTHCT PF08070.11 ORY04402.1 - 0.42 11.4 10.2 0.08 13.7 2.9 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region Arrestin_C PF02752.22 ORY04403.1 - 6.1e-12 46.2 0.0 1.6e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY04403.1 - 7.2e-10 39.1 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY04403.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Arrestin_N terminal like VHL PF01847.16 ORY04403.1 - 0.025 14.5 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain Vac_ImportDeg PF09783.9 ORY04404.1 - 4.1e-63 212.0 7.1 4.7e-63 211.8 7.1 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein ECH_2 PF16113.5 ORY04405.1 - 1.6e-113 379.6 0.0 2e-113 379.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY04405.1 - 1.4e-21 77.0 0.0 7.5e-21 74.6 0.0 2.0 1 1 2 3 3 3 1 Enoyl-CoA hydratase/isomerase 2OG-FeII_Oxy_2 PF13532.6 ORY04406.1 - 1.3e-29 103.8 0.0 1.6e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thg1 PF04446.12 ORY04407.1 - 1.4e-52 177.0 0.0 1.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 ORY04407.1 - 1.3e-42 144.8 0.9 4.3e-42 143.1 0.9 1.8 1 1 0 1 1 1 1 Thg1 C terminal domain HTH_psq PF05225.16 ORY04407.1 - 0.067 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain USP7_C2 PF14533.6 ORY04409.1 - 2e-72 243.2 0.8 1.1e-69 234.3 0.2 3.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 ORY04409.1 - 2.5e-70 236.5 0.0 3.3e-68 229.6 0.0 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 ORY04409.1 - 3.3e-48 164.4 0.4 5.2e-48 163.8 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY04409.1 - 3.3e-19 69.6 0.0 7.7e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORY04409.1 - 1.8e-10 41.0 0.0 1.3e-09 38.2 0.0 2.5 2 1 1 3 3 3 1 MATH domain Rad60-SLD PF11976.8 ORY04409.1 - 0.0049 16.7 4.1 2.8 7.9 0.0 5.2 4 2 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like zf-C2H2 PF00096.26 ORY04410.1 - 9.9e-35 117.1 69.0 0.00052 20.3 0.3 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY04410.1 - 2.6e-20 71.3 66.3 0.0034 18.1 0.2 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY04410.1 - 7.1e-17 61.0 76.3 5.4e-05 23.4 1.3 11.3 11 1 0 11 11 11 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY04410.1 - 2.3e-08 34.3 31.4 0.0052 17.1 6.9 5.2 2 1 3 5 5 5 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY04410.1 - 1.1e-06 28.7 34.9 0.00021 21.5 0.7 7.7 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY04410.1 - 3.8e-05 23.9 26.1 0.0089 16.4 0.4 7.3 7 0 0 7 7 7 3 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORY04410.1 - 0.0039 17.8 30.3 0.37 11.5 0.0 7.7 3 2 5 8 8 8 1 FOXP coiled-coil domain Prok-RING_4 PF14447.6 ORY04410.1 - 0.026 14.4 3.1 0.61 10.0 0.6 3.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 ORY04410.1 - 0.048 14.0 2.1 0.048 14.0 2.1 5.9 5 2 2 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_12 PF18658.1 ORY04410.1 - 0.13 11.9 4.2 0.95 9.1 0.0 3.4 2 1 2 4 4 4 0 Zinc-finger C2H2-type OrsD PF12013.8 ORY04410.1 - 0.16 12.4 0.1 0.16 12.4 0.1 5.5 4 2 1 5 5 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_9 PF16293.5 ORY04410.1 - 0.21 11.5 8.7 0.44 10.4 0.1 4.4 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 ORY04410.1 - 0.49 10.5 0.1 0.49 10.5 0.1 5.3 5 1 0 5 5 5 0 BED zinc finger zf-C2HC_2 PF13913.6 ORY04410.1 - 2 8.4 9.1 1.7 8.7 0.2 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Ogr_Delta PF04606.12 ORY04410.1 - 2 8.4 0.0 2 8.4 0.0 4.7 5 1 2 7 7 6 0 Ogr/Delta-like zinc finger IBR PF01485.21 ORY04410.1 - 8.3 6.7 30.9 1.1 9.6 1.6 5.4 4 1 1 5 5 5 0 IBR domain, a half RING-finger domain CAF1A PF12253.8 ORY04411.1 - 3.7e-25 87.9 9.8 3.7e-25 87.9 9.8 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A AAA_23 PF13476.6 ORY04411.1 - 0.31 11.5 23.2 0.7 10.4 23.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY04411.1 - 0.56 9.9 11.7 1.2 8.9 11.7 1.5 1 0 0 1 1 1 0 AAA domain GREB1 PF15782.5 ORY04411.1 - 2 5.4 11.6 3.6 4.6 11.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LicD PF04991.13 ORY04411.1 - 4.4 7.4 9.7 10 6.2 9.7 1.6 1 0 0 1 1 1 0 LicD family HAT_KAT11 PF08214.11 ORY04412.1 - 6.8e-38 130.8 0.8 8.4e-38 130.5 0.8 1.1 1 0 0 1 1 1 1 Histone acetylation protein Mt_ATP-synt_D PF05873.12 ORY04413.1 - 3.2e-21 75.8 3.0 3.8e-21 75.5 3.0 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Pet20 PF08692.10 ORY04413.1 - 0.00024 21.8 0.0 0.00058 20.6 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial protein Pet20 HALZ PF02183.18 ORY04413.1 - 0.01 16.0 1.8 0.13 12.5 0.3 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 ORY04413.1 - 0.019 15.0 0.6 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) 120_Rick_ant PF12574.8 ORY04413.1 - 0.02 14.1 1.1 0.1 11.7 1.1 1.8 1 1 0 1 1 1 0 120 KDa Rickettsia surface antigen ZapB PF06005.12 ORY04413.1 - 0.037 14.4 1.0 1.4 9.4 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF2408 PF10303.9 ORY04413.1 - 0.048 14.2 1.6 0.59 10.7 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 ORY04413.1 - 0.071 13.2 3.4 4.8 7.2 0.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APC_N_CC PF16689.5 ORY04413.1 - 0.14 12.3 0.7 6.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Spc24 PF08286.11 ORY04413.1 - 0.29 11.4 3.6 4.5 7.6 0.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 ORY04413.1 - 0.41 10.9 4.5 2.1 8.6 0.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 ORY04413.1 - 0.56 10.0 4.1 9.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF2570 PF10828.8 ORY04413.1 - 0.9 9.4 3.5 6.9 6.5 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) AMP-binding PF00501.28 ORY04414.1 - 2.3e-95 319.7 0.0 3e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY04414.1 - 2e-05 25.5 0.0 4.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_tranf_2_3 PF13641.6 ORY04415.1 - 2.4e-27 96.3 0.0 3.1e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY04415.1 - 2.6e-09 36.8 0.2 1.3e-08 34.5 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY04415.1 - 1.9e-08 34.3 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 ORY04415.1 - 0.00039 20.4 6.0 0.0014 18.6 6.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Pkinase PF00069.25 ORY04416.1 - 4e-60 203.4 0.0 4.9e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04416.1 - 1.9e-27 96.2 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY04416.1 - 4.8e-08 32.3 0.1 5.9e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY04416.1 - 5.4e-06 25.9 0.0 3.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY04416.1 - 1.3e-05 25.3 0.1 0.0039 17.1 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY04416.1 - 1.6e-05 24.4 0.5 3.1e-05 23.4 0.5 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY04416.1 - 0.00034 19.5 0.0 0.00052 18.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 ORY04416.1 - 0.039 13.5 0.2 0.062 12.9 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PRCC PF10253.9 ORY04418.1 - 2.8e-26 93.6 12.7 2.8e-26 93.6 12.7 2.1 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting BUD22 PF09073.10 ORY04419.1 - 3.3 6.9 42.5 3.9 6.7 42.5 1.0 1 0 0 1 1 1 0 BUD22 DUF3336 PF11815.8 ORY04420.1 - 1.8e-44 150.8 4.0 3e-44 150.1 4.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY04420.1 - 9.5e-18 65.1 0.0 4e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase HemY_N PF07219.13 ORY04420.1 - 0.16 12.2 0.7 1.6 8.9 0.2 2.3 2 0 0 2 2 2 0 HemY protein N-terminus CNH PF00780.22 ORY04421.1 - 1.5e-36 126.5 0.0 2.6e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY04421.1 - 1.4e-16 61.3 0.4 3.3e-16 60.1 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY04421.1 - 2e-15 57.1 0.7 5.7e-09 36.2 0.3 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain DEP PF00610.21 ORY04421.1 - 4.1e-11 42.8 0.1 1.2e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 ORY04421.1 - 8.9e-07 28.8 0.2 2.5e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ORY04421.1 - 3.3e-06 27.6 0.0 8.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Ribosomal_L35Ae PF01247.18 ORY04422.1 - 1.4e-45 153.4 0.7 1.6e-45 153.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY04422.1 - 0.0091 16.2 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain NPL4 PF05021.15 ORY04423.1 - 1.1e-133 445.3 0.0 1.4e-133 445.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 ORY04423.1 - 1.5e-70 235.9 0.3 2.8e-70 235.1 0.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 ORY04423.1 - 2e-10 41.0 0.0 4.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 ORY04423.1 - 0.013 14.8 3.6 0.013 14.8 3.6 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Response_reg PF00072.24 ORY04424.1 - 9e-21 74.1 0.0 1.5e-20 73.5 0.0 1.3 1 1 0 1 1 1 1 Response regulator receiver domain T-box PF00907.22 ORY04425.1 - 1.8e-51 175.1 0.7 3.1e-51 174.3 0.7 1.4 1 0 0 1 1 1 1 T-box Scs3p PF10261.9 ORY04426.1 - 1.4e-47 162.3 27.0 1.9e-35 122.6 10.9 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Tudor_3 PF18115.1 ORY04427.1 - 3.4e-13 49.2 0.1 5.3e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 ORY04427.1 - 1.3e-09 38.4 0.0 1.9e-05 25.0 0.0 3.0 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY04427.1 - 2.3e-08 34.3 0.1 0.00025 21.3 0.0 3.5 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 ORY04427.1 - 2.3e-08 34.0 0.1 3.1e-05 24.0 0.1 3.4 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Tudor_2 PF18104.1 ORY04427.1 - 6.6e-07 28.9 0.8 2.9e-05 23.7 0.2 2.5 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain LBR_tudor PF09465.10 ORY04427.1 - 2.3e-06 27.3 0.1 6e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 ORY04427.1 - 1.5e-05 25.0 0.5 0.00086 19.4 0.0 2.6 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 ORY04427.1 - 4.4e-05 23.5 0.6 0.018 15.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 ORY04427.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor RTT107_BRCT_5 PF16770.5 ORY04427.1 - 0.00046 20.0 0.1 0.0026 17.6 0.0 2.3 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain TUDOR_5 PF18359.1 ORY04427.1 - 0.0015 18.1 0.1 0.0039 16.9 0.1 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 eIF-1a PF01176.19 ORY04427.1 - 0.0055 16.5 0.0 5.7 6.8 0.0 2.7 2 0 0 2 2 2 2 Translation initiation factor 1A / IF-1 CDP-OH_P_transf PF01066.21 ORY04428.1 - 1.2e-17 64.4 0.2 1.2e-17 64.4 0.2 3.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_S8 PF00082.22 ORY04429.1 - 2.3e-37 128.9 0.1 4.4e-37 127.9 0.1 1.5 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY04429.1 - 1.4e-25 89.1 0.1 3.1e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY04429.1 - 0.001 19.8 0.6 0.0034 18.1 0.6 2.0 1 0 0 1 1 1 1 Peptidase S8 pro-domain CENP-C_C PF11699.8 ORY04431.1 - 6.2e-29 100.1 0.7 1.1e-28 99.3 0.7 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 ORY04431.1 - 4.5e-12 46.8 1.5 4.5e-12 46.8 1.5 2.6 2 0 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 ORY04431.1 - 6.2e-06 25.8 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Spc7 PF08317.11 ORY04432.1 - 5.1e-05 22.3 21.9 5.1e-05 22.3 21.9 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein fn3 PF00041.21 ORY04432.1 - 0.11 12.8 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain DUF3869 PF12985.7 ORY04432.1 - 0.21 12.0 2.1 0.33 11.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) Prominin PF05478.11 ORY04432.1 - 0.34 8.8 17.0 0.55 8.1 17.0 1.3 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 ORY04432.1 - 0.45 10.6 23.6 0.62 10.1 4.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ZnuA PF01297.17 ORY04432.1 - 0.58 9.5 7.5 0.64 9.4 6.0 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic COG2 PF06148.11 ORY04432.1 - 0.63 10.1 23.9 0.38 10.9 4.2 3.7 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 ORY04432.1 - 1.5 8.9 17.6 0.11 12.5 7.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus E2F_CC-MB PF16421.5 ORY04432.1 - 1.9 8.9 11.9 2.4 8.6 3.1 3.0 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain CorA PF01544.18 ORY04432.1 - 2.6 7.3 25.2 0.36 10.1 6.0 2.8 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Golgin_A5 PF09787.9 ORY04432.1 - 3.8 6.9 37.5 13 5.2 25.9 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 ORY04432.1 - 4.5 7.5 25.7 2.5 8.3 12.0 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family E1-E2_ATPase PF00122.20 ORY04433.1 - 1.3e-49 168.1 0.3 1.3e-49 168.1 0.3 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY04433.1 - 4.1e-38 131.8 0.6 2.3e-36 126.1 0.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY04433.1 - 1.7e-06 28.0 0.7 0.0008 19.2 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY04433.1 - 0.00012 22.6 0.0 0.00031 21.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY04433.1 - 0.0023 18.0 0.3 0.91 9.7 0.0 3.5 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase TelA PF05816.11 ORY04433.1 - 0.14 11.2 0.0 5.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) EIID-AGA PF03613.14 ORY04433.1 - 0.71 9.0 7.6 4.2 6.5 0.5 2.9 2 1 0 3 3 3 0 PTS system mannose/fructose/sorbose family IID component Peptidase_S28 PF05577.12 ORY04434.1 - 2.1e-77 260.8 0.0 2.8e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 ORY04434.1 - 0.0006 19.4 0.1 0.00098 18.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY04434.1 - 0.028 14.1 0.1 0.066 12.8 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold GHL13 PF14883.6 ORY04434.1 - 0.16 11.0 0.0 0.35 9.9 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 GPI-anchored PF10342.9 ORY04435.1 - 1.5e-11 44.9 2.5 2.1e-11 44.4 0.0 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mid2 PF04478.12 ORY04435.1 - 0.14 11.9 0.2 2.1 8.1 0.1 2.5 2 1 0 3 3 3 0 Mid2 like cell wall stress sensor DUF4203 PF13886.6 ORY04436.1 - 4.5e-34 117.9 38.8 5.4e-34 117.6 38.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2613 PF11021.8 ORY04436.1 - 0.27 11.4 0.1 0.27 11.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) adh_short PF00106.25 ORY04437.1 - 1.6e-45 155.0 0.0 2e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY04437.1 - 2.5e-33 115.6 0.0 3.3e-33 115.2 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY04437.1 - 3.1e-09 37.0 0.0 3.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY04437.1 - 0.021 14.7 0.2 0.035 14.0 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 ORY04437.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Chitin_synth_1 PF01644.17 ORY04486.1 - 7.1e-71 237.5 0.1 1e-70 236.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY04486.1 - 1.9e-30 104.6 0.1 3.9e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY04486.1 - 1.7e-26 93.0 3.1 7.2e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY04486.1 - 3.5e-07 30.3 0.1 3.5e-07 30.3 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY04486.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 AgrD PF05931.11 ORY04486.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 Staphylococcal AgrD protein zf-C2H2 PF00096.26 ORY04487.1 - 6e-17 61.1 19.5 1.9e-06 28.0 1.7 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY04487.1 - 2.1e-16 59.5 18.3 7.9e-08 32.4 2.8 3.5 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY04487.1 - 2.9e-13 49.4 16.3 0.00046 20.8 2.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY04487.1 - 3.6e-09 36.4 12.3 9.6e-05 22.3 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY04487.1 - 4.3e-06 26.9 6.1 0.022 15.0 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORY04487.1 - 8.9e-05 22.9 8.9 0.27 11.7 0.7 3.1 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 ORY04487.1 - 0.00014 21.9 2.7 3 8.0 0.0 3.2 2 1 1 3 3 3 2 Zic proteins zinc finger domain zf-met PF12874.7 ORY04487.1 - 0.0014 19.0 7.3 5.1 7.6 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 ORY04487.1 - 0.0016 18.0 3.8 0.93 9.1 0.2 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 ORY04487.1 - 0.0019 18.9 6.7 0.024 15.3 0.5 2.7 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 ORY04487.1 - 0.0022 18.3 2.1 0.0022 18.3 2.1 1.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORY04487.1 - 0.0051 16.5 10.7 0.065 13.0 0.1 3.5 4 0 0 4 4 4 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 ORY04487.1 - 0.011 15.8 10.5 0.33 11.1 0.7 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.16 ORY04487.1 - 0.017 15.3 15.1 1.4 9.1 1.8 3.3 1 1 2 3 3 3 0 AN1-like Zinc finger C1_1 PF00130.22 ORY04487.1 - 0.034 14.0 3.7 1.2 9.0 0.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 ORY04487.1 - 0.037 13.9 2.7 0.037 13.9 2.7 3.2 3 1 0 3 3 3 0 zinc-finger of a C2HC-type CpXC PF14353.6 ORY04487.1 - 0.052 13.6 6.0 8.1 6.5 0.1 3.0 1 1 2 3 3 3 0 CpXC protein zinc_ribbon_15 PF17032.5 ORY04487.1 - 0.053 14.3 2.7 0.12 13.2 2.7 1.6 1 1 0 1 1 1 0 zinc-ribbon family zf-BED PF02892.15 ORY04487.1 - 0.064 13.3 8.5 0.26 11.3 1.6 2.8 1 1 2 3 3 3 0 BED zinc finger DUF2757 PF10955.8 ORY04487.1 - 0.18 12.1 3.8 5 7.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) zf-ZPR1 PF03367.13 ORY04487.1 - 0.23 11.3 1.5 0.82 9.5 1.2 1.9 1 1 1 2 2 2 0 ZPR1 zinc-finger domain HypA PF01155.19 ORY04487.1 - 0.23 11.5 3.1 0.17 11.9 1.4 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 ORY04487.1 - 0.35 10.9 9.6 3 7.9 0.3 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DZR PF12773.7 ORY04487.1 - 0.5 10.4 6.3 1.9 8.6 6.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 ORY04487.1 - 0.53 9.8 5.3 3.5 7.2 0.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORY04487.1 - 0.55 10.2 5.2 3.3 7.8 5.2 2.4 1 1 0 1 1 1 0 zinc-ribbons LIM PF00412.22 ORY04487.1 - 0.99 9.7 7.9 1 9.6 5.0 2.3 1 1 1 2 2 2 0 LIM domain zinc_ribbon_4 PF13717.6 ORY04487.1 - 1 9.3 7.6 6.5 6.8 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain RNHCP PF12647.7 ORY04487.1 - 1.6 8.7 8.7 0.66 10.0 0.8 2.6 2 1 0 3 3 3 0 RNHCP domain zf-LYAR PF08790.11 ORY04487.1 - 2.2 8.2 10.9 29 4.7 2.0 3.6 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 ORY04487.1 - 3.2 8.1 10.7 1.4 9.2 4.4 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain DUF983 PF06170.12 ORY04487.1 - 5 7.6 4.6 8.3 6.9 0.1 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF983) XPA_N PF01286.18 ORY04487.1 - 6.3 6.9 13.3 2.1 8.5 0.4 3.4 4 0 0 4 4 3 0 XPA protein N-terminal Adenylsucc_synt PF00709.21 ORY04488.1 - 2e-183 610.1 0.0 2.3e-183 609.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase GAF PF01590.26 ORY04488.1 - 0.0099 16.5 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain KHA PF11834.8 ORY04488.1 - 0.051 13.7 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel CBM_19 PF03427.13 ORY04489.1 - 9.5e-05 22.3 0.8 9.5e-05 22.3 0.8 2.6 2 1 0 2 2 2 1 Carbohydrate binding domain (family 19) BKACE PF05853.12 ORY04489.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Na_H_Exchanger PF00999.21 ORY04491.1 - 8.3e-58 196.0 36.3 1.1e-57 195.7 36.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY04491.1 - 0.046 13.8 0.9 0.046 13.8 0.9 3.2 4 0 0 4 4 4 0 YrhC-like protein WD40 PF00400.32 ORY04492.1 - 3.8e-53 176.3 18.4 1.2e-09 38.7 0.2 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04492.1 - 4.1e-28 97.5 0.3 4.8e-05 23.6 0.0 7.0 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORY04492.1 - 2.4e-09 36.8 0.7 4.2e-09 36.0 0.7 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 ORY04492.1 - 3.2e-09 37.0 0.5 0.014 15.2 0.1 3.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY04492.1 - 5.7e-08 32.4 0.0 0.0028 17.0 0.0 3.3 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 ORY04492.1 - 0.0025 16.6 0.2 0.011 14.4 0.0 2.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY04492.1 - 0.0055 15.7 0.3 8.6 5.2 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 ORY04492.1 - 0.012 14.9 0.0 1.3 8.3 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 ORY04492.1 - 0.072 13.0 0.6 0.91 9.5 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 ORY04492.1 - 0.073 11.1 1.1 0.27 9.2 0.1 2.2 1 1 0 2 2 2 0 IKI3 family Atrophin-1 PF03154.15 ORY04492.1 - 6.1 5.0 11.3 8.3 4.5 11.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Na_H_Exchanger PF00999.21 ORY04493.1 - 3.5e-50 170.9 27.0 2.6e-49 168.0 27.0 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3112 PF11309.8 ORY04493.1 - 0.053 13.0 0.6 0.15 11.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Sec6 PF06046.13 ORY04494.1 - 2.5e-133 445.5 8.7 2.5e-133 445.5 8.7 1.6 2 1 1 3 3 3 1 Exocyst complex component Sec6 Macscav_rec PF03523.13 ORY04494.1 - 0.29 11.0 2.2 0.83 9.6 0.3 2.6 2 0 0 2 2 2 0 Macrophage scavenger receptor RIH_assoc PF08454.11 ORY04494.1 - 0.39 10.6 7.0 0.42 10.5 1.8 3.3 2 1 1 3 3 3 0 RyR and IP3R Homology associated EB1 PF03271.17 ORY04495.1 - 1.6e-09 37.9 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORY04495.1 - 1.6e-07 31.5 0.2 3.1e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain SlyX PF04102.12 ORY04495.1 - 0.014 16.0 0.8 0.034 14.7 0.8 1.6 1 0 0 1 1 1 0 SlyX TSC22 PF01166.18 ORY04495.1 - 0.047 14.0 0.1 0.095 13.0 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family CH_2 PF06294.11 ORY04495.1 - 0.1 12.7 0.2 0.34 11.1 0.1 1.9 2 0 0 2 2 2 0 CH-like domain in sperm protein Ank_4 PF13637.6 ORY04496.1 - 6.7e-18 64.8 0.5 5.2e-14 52.4 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY04496.1 - 5.7e-16 58.9 0.3 1.3e-15 57.7 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY04496.1 - 1.1e-15 57.3 0.8 4.5e-08 33.2 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY04496.1 - 5e-12 44.9 0.3 5.2e-05 23.3 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY04496.1 - 2.6e-10 40.3 0.1 2.3e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 ORY04496.1 - 0.067 13.7 0.1 0.23 12.0 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1843) PH PF00169.29 ORY04497.1 - 4.5e-12 46.4 1.1 9.1e-12 45.4 0.6 1.8 1 1 1 2 2 2 1 PH domain NatB_MDM20 PF09797.9 ORY04503.1 - 0.5 9.2 0.9 7.1 5.4 0.3 2.0 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit Bac_surface_Ag PF01103.23 ORY04504.1 - 8.5e-53 179.9 0.5 1.1e-52 179.6 0.5 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 ORY04504.1 - 0.047 14.3 1.6 0.083 13.5 0.1 2.1 2 0 0 2 2 2 0 Surface antigen variable number repeat SAS4 PF15460.6 ORY04504.1 - 0.27 11.4 3.2 0.5 10.5 3.2 1.3 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Sec61_beta PF03911.16 ORY04505.1 - 2.9e-16 59.2 0.5 3.3e-16 59.0 0.5 1.1 1 0 0 1 1 1 1 Sec61beta family Trypsin PF00089.26 ORY04506.1 - 3.8e-45 154.4 0.0 4.3e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY04506.1 - 1.2e-08 36.0 0.1 2.3e-08 35.1 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 ORY04506.1 - 0.0015 18.1 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 tRNA-synt_1 PF00133.22 ORY04507.1 - 1.7e-233 776.3 0.2 2.5e-233 775.8 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY04507.1 - 7.7e-30 103.9 0.1 4.4e-29 101.4 0.1 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY04507.1 - 9.7e-14 50.9 3.1 6.2e-05 21.9 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ORY04507.1 - 0.0015 17.9 0.0 0.0049 16.2 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ThiF PF00899.21 ORY04508.1 - 1.5e-18 67.1 0.0 2.7e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORY04508.1 - 0.00012 22.2 0.0 0.3 11.3 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle EPSP_synthase PF00275.20 ORY04509.1 - 1.3e-126 422.7 0.0 2e-126 422.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORY04509.1 - 3e-97 324.9 0.0 7.9e-97 323.5 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ORY04509.1 - 2.5e-54 184.9 0.0 6.1e-54 183.7 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 ORY04509.1 - 4.3e-34 117.9 0.1 1.8e-32 112.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 ORY04509.1 - 1.7e-24 85.8 0.0 6.1e-24 84.1 0.0 2.1 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ORY04509.1 - 2.4e-08 34.2 0.1 5.1e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 ORY04509.1 - 1.6e-07 31.3 0.0 1.3e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 ORY04509.1 - 1e-05 25.2 0.4 2.7e-05 23.8 0.4 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_16 PF13191.6 ORY04509.1 - 0.0041 17.5 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORY04509.1 - 0.021 15.2 0.0 0.077 13.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrkA_N PF02254.18 ORY04509.1 - 0.023 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 1 0 TrkA-N domain AAA_2 PF07724.14 ORY04509.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY04509.1 - 0.034 14.3 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY04509.1 - 0.06 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY04509.1 - 0.062 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sporozoite_P67 PF05642.11 ORY04509.1 - 0.071 11.2 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zeta_toxin PF06414.12 ORY04509.1 - 0.091 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 ORY04509.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY04509.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hjc PF01870.18 ORY04510.1 - 0.02 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Fungal_trans PF04082.18 ORY04511.1 - 1e-32 113.3 0.3 7.6e-32 110.4 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY04512.1 - 2.4e-10 40.4 12.4 3.6e-10 39.8 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRE1 PF08647.11 ORY04513.1 - 5.7e-11 42.4 17.9 5.7e-11 42.4 17.9 8.9 6 2 3 9 9 9 4 BRE1 E3 ubiquitin ligase DUF2703 PF10865.8 ORY04513.1 - 0.046 13.9 0.4 0.046 13.9 0.4 5.2 5 2 1 6 6 6 0 Domain of unknown function (DUF2703) Carboxyl_trans PF01039.22 ORY04514.1 - 1e-129 433.4 0.0 1.4e-129 432.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Ras PF00071.22 ORY04515.1 - 1.9e-59 199.9 0.6 2.4e-59 199.5 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY04515.1 - 2.8e-36 124.4 0.1 4.8e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY04515.1 - 1.7e-14 53.7 0.2 2e-14 53.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY04515.1 - 5.5e-06 26.1 0.2 8.6e-05 22.2 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY04515.1 - 1.3e-05 24.7 0.1 2.5e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY04515.1 - 4.6e-05 23.5 0.1 0.00011 22.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY04515.1 - 7.7e-05 22.7 0.0 0.078 12.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 ORY04515.1 - 0.00012 21.5 0.2 0.00015 21.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 ORY04515.1 - 0.0049 16.7 0.1 0.016 15.0 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 ORY04515.1 - 0.069 12.5 0.1 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein TIR_2 PF13676.6 ORY04515.1 - 0.091 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 TIR domain TUG-UBL1 PF11470.8 ORY04516.1 - 5.2e-19 68.2 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 ORY04516.1 - 5.8e-10 39.2 0.1 1.4e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 UBX domain Cobl PF09469.10 ORY04516.1 - 0.00066 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain Bromodomain PF00439.25 ORY04517.1 - 2.5e-17 62.7 0.8 7.2e-17 61.2 0.3 2.0 2 0 0 2 2 2 1 Bromodomain Peptidase_S8 PF00082.22 ORY04518.1 - 2.2e-38 132.2 8.3 3.6e-38 131.5 8.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY04518.1 - 1.1e-14 54.9 0.2 2e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF5550 PF17704.1 ORY04518.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5550) Candida_ALS PF05792.13 ORY04518.1 - 0.88 10.2 4.0 2.2 9.0 4.0 1.6 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) SNF2_N PF00176.23 ORY04519.1 - 6.2e-72 242.2 0.8 6.2e-72 242.2 0.8 3.1 3 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY04519.1 - 1.3e-18 67.4 0.0 1.3e-18 67.4 0.0 4.5 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.13 ORY04519.1 - 1.3e-18 67.0 7.5 1.3e-18 67.0 7.5 6.0 4 2 1 5 5 5 1 HSA Bromodomain PF00439.25 ORY04519.1 - 2.2e-18 66.1 0.1 7.6e-18 64.4 0.1 2.0 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 ORY04519.1 - 2.8e-11 43.8 4.3 2.8e-11 43.8 4.3 4.6 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ORY04519.1 - 2.4e-10 40.7 0.1 2.4e-10 40.7 0.1 4.2 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit FMO-like PF00743.19 ORY04520.1 - 1.2e-56 192.3 0.1 6.3e-40 137.1 0.0 2.7 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY04520.1 - 8.5e-19 67.9 0.0 4.7e-13 49.1 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY04520.1 - 3.7e-16 59.2 0.0 8e-16 58.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY04520.1 - 2.8e-11 43.2 0.3 2.8e-09 36.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY04520.1 - 3.7e-11 43.2 0.1 1.1e-09 38.4 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ORY04520.1 - 5.1e-11 42.8 0.2 3.9e-05 23.4 0.1 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY04520.1 - 1.3e-10 41.4 0.3 1.7e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY04520.1 - 6.7e-07 29.8 0.3 0.096 13.3 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY04520.1 - 1e-06 28.2 0.1 0.00015 21.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 ORY04520.1 - 1.2e-05 24.9 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORY04520.1 - 7.7e-05 21.6 0.3 0.00051 18.8 0.2 2.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY04520.1 - 0.00035 19.8 0.4 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ORY04520.1 - 0.00044 19.4 0.9 0.0031 16.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORY04520.1 - 0.00054 19.3 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain GFO_IDH_MocA PF01408.22 ORY04520.1 - 0.024 15.5 0.3 0.43 11.4 0.1 2.7 4 0 0 4 4 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 ORY04520.1 - 0.031 14.7 0.4 9.9 6.7 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding MCRA PF06100.11 ORY04520.1 - 0.074 11.8 0.1 1 8.0 0.0 2.1 2 0 0 2 2 2 0 MCRA family DUF1344 PF07076.11 ORY04520.1 - 0.17 11.8 1.8 0.65 10.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) AlaDh_PNT_C PF01262.21 ORY04520.1 - 0.25 10.6 0.3 1.4 8.2 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ORY04520.1 - 0.27 11.5 0.8 0.83 9.9 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain KASH_CCD PF14662.6 ORY04521.1 - 0.013 15.3 2.0 0.02 14.7 2.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fungal_TACC PF12709.7 ORY04521.1 - 0.061 13.8 1.1 0.11 13.0 1.1 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Arrestin_C PF02752.22 ORY04522.1 - 9.1e-05 22.9 1.8 0.00019 21.9 1.8 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF1082 PF06449.11 ORY04524.1 - 0.041 13.7 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) AA_permease_2 PF13520.6 ORY04525.1 - 1.8e-60 205.0 37.4 2.1e-60 204.8 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY04525.1 - 1.7e-15 56.6 40.0 3.5e-15 55.6 40.0 1.5 1 1 0 1 1 1 1 Amino acid permease CBAH PF02275.18 ORY04526.1 - 0.012 15.3 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF5320 PF17253.2 ORY04527.1 - 0.0089 17.1 1.3 0.016 16.3 1.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5320) FlaG PF03646.15 ORY04527.1 - 0.31 11.2 2.5 0.21 11.7 0.3 1.8 2 0 0 2 2 2 0 FlaG protein Helicase_C PF00271.31 ORY04528.1 - 3.7e-09 36.9 0.0 4.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 ORY04585.1 - 1.8e-41 141.9 0.0 3.6e-22 79.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY04585.1 - 4.5e-13 49.7 6.7 0.013 15.3 0.0 4.5 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY04585.1 - 1.6e-06 27.8 0.3 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 ORY04585.1 - 3.5e-06 26.6 0.2 0.44 9.9 0.0 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ORY04585.1 - 5.1e-05 23.4 0.0 0.38 11.0 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 ORY04585.1 - 5.5e-05 23.5 0.5 0.53 10.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY04585.1 - 0.00015 22.1 0.1 0.29 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY04585.1 - 0.00017 21.5 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 ORY04585.1 - 0.00028 20.7 0.2 2 8.1 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORY04585.1 - 0.00077 20.0 1.2 15 6.2 0.4 4.3 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 ORY04585.1 - 0.00081 19.6 0.2 1.8 8.7 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 ORY04585.1 - 0.002 17.9 0.3 0.76 9.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ORY04585.1 - 0.0026 17.9 0.2 0.021 14.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY04585.1 - 0.0036 17.4 0.0 2.3 8.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 ORY04585.1 - 0.0039 17.2 0.0 1.9 8.5 0.0 3.1 2 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 ORY04585.1 - 0.0043 16.8 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 ORY04585.1 - 0.006 17.0 0.0 2.1 8.7 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 ORY04585.1 - 0.01 15.4 0.2 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 ORY04585.1 - 0.03 13.8 0.0 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 ORY04585.1 - 0.031 14.8 5.0 0.13 12.8 0.2 3.3 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 ORY04585.1 - 0.032 14.1 0.5 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 ORY04585.1 - 0.042 14.3 0.0 15 6.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ORY04585.1 - 0.048 13.9 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ORY04585.1 - 0.058 13.4 0.1 16 5.5 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 ORY04585.1 - 0.073 12.5 0.0 7.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 ORY04585.1 - 0.085 12.0 0.2 6.1 5.9 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain AAA_25 PF13481.6 ORY04585.1 - 0.086 12.4 0.4 2.5 7.6 0.1 2.9 4 0 0 4 4 3 0 AAA domain dNK PF01712.19 ORY04585.1 - 0.1 12.4 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Ploopntkinase1 PF18748.1 ORY04585.1 - 0.11 12.1 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 1 0 P-loop Nucleotide Kinase1 T2SSE PF00437.20 ORY04585.1 - 0.11 11.5 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 ORY04585.1 - 0.12 11.9 0.4 0.8 9.2 0.0 2.2 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain KOG2701 PF09762.9 ORY04585.1 - 0.16 12.2 0.4 8.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) AAA_15 PF13175.6 ORY04585.1 - 0.68 9.6 2.4 5 6.7 0.1 2.9 4 0 0 4 4 4 0 AAA ATPase domain ABC_membrane PF00664.23 ORY04586.1 - 3.3e-81 272.9 26.4 4.6e-42 144.5 5.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY04586.1 - 9.3e-52 175.2 0.0 5.2e-30 104.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY04586.1 - 1.5e-08 34.3 3.9 0.0063 16.0 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 ORY04586.1 - 9.2e-06 25.9 3.2 0.054 13.6 0.2 2.9 3 0 0 3 3 3 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 ORY04586.1 - 1.2e-05 25.4 2.4 0.064 13.3 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY04586.1 - 0.00045 20.2 0.5 0.077 12.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY04586.1 - 0.001 19.5 0.0 0.45 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORY04586.1 - 0.0019 17.9 2.7 0.76 9.6 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY04586.1 - 0.005 17.1 0.3 2.9 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ORY04586.1 - 0.0053 16.4 0.1 0.48 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY04586.1 - 0.0087 15.6 0.1 0.56 9.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_PrkA PF08298.11 ORY04586.1 - 0.039 12.9 0.1 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_21 PF13304.6 ORY04586.1 - 0.074 12.8 2.0 16 5.2 0.0 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 ORY04586.1 - 0.13 12.5 0.1 30 4.9 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 ORY04586.1 - 0.13 11.6 0.8 4.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AIG1 family TrwB_AAD_bind PF10412.9 ORY04586.1 - 0.14 11.1 0.1 12 4.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ORY04586.1 - 0.19 12.2 1.5 27 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ORY04586.1 - 0.19 11.8 4.5 0.48 10.5 0.6 2.4 2 0 0 2 2 2 0 Dynamin family DUF2183 PF09949.9 ORY04587.1 - 6.4e-31 106.6 0.0 2.2e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 ORY04587.1 - 0.075 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) CwfJ_C_1 PF04677.15 ORY04588.1 - 7.3e-32 109.8 0.3 1.5e-31 108.8 0.3 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ORY04588.1 - 9.7e-31 106.6 0.5 9.7e-31 106.6 0.5 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 GCP_N_terminal PF17681.1 ORY04589.1 - 1.4e-83 281.0 0.7 1.4e-83 281.0 0.7 2.1 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY04589.1 - 1.9e-78 264.1 12.4 1.9e-78 264.1 12.4 2.3 3 1 1 4 4 4 1 Gamma tubulin complex component C-terminal eIF2A PF08662.11 ORY04590.1 - 2.3e-37 128.8 1.2 3.2e-31 108.7 0.2 5.2 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORY04590.1 - 0.0084 15.9 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAXIP1_C PF15364.6 ORY04590.1 - 0.018 15.4 0.3 11 6.3 0.3 2.7 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Ribosomal_L4 PF00573.22 ORY04590.1 - 0.035 13.8 0.2 0.25 11.0 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L4/L1 family ANAPC4_WD40 PF12894.7 ORY04590.1 - 0.051 13.9 0.0 32 4.9 0.0 4.6 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY04590.1 - 0.084 13.8 1.5 2.7 9.0 0.0 3.6 3 1 0 3 3 3 0 WD domain, G-beta repeat HalX PF08663.10 ORY04590.1 - 0.8 10.1 6.4 0.75 10.2 0.2 2.6 2 0 0 2 2 2 0 HalX domain DSBA PF01323.20 ORY04591.1 - 2.7e-31 108.8 0.0 3.2e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY04591.1 - 0.00033 20.8 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 ORY04591.1 - 0.01 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain NUDIX PF00293.28 ORY04592.1 - 7.9e-12 45.4 1.4 9.1e-12 45.2 1.4 1.1 1 0 0 1 1 1 1 NUDIX domain DS PF01916.17 ORY04593.1 - 4.6e-134 446.2 0.0 5.3e-134 446.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SH3_9 PF14604.6 ORY04594.1 - 4e-37 125.8 8.1 1.7e-12 47.0 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 ORY04594.1 - 5.5e-36 121.9 10.6 9.4e-13 47.6 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 ORY04594.1 - 3e-32 110.2 0.0 6.1e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 ORY04594.1 - 1.1e-24 85.8 0.0 5.7e-10 38.7 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 ORY04594.1 - 2.3e-10 40.3 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IRS PF02174.17 ORY04594.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 PTB domain (IRS-1 type) SURF4 PF02077.15 ORY04595.1 - 3.7e-92 308.7 12.5 4.2e-92 308.5 12.5 1.0 1 0 0 1 1 1 1 SURF4 family DnaJ PF00226.31 ORY04596.1 - 8.4e-29 99.5 0.5 8.4e-29 99.5 0.5 2.2 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 ORY04596.1 - 5.5e-15 54.5 0.6 4.6e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY04596.1 - 1.6e-10 40.5 0.1 8.1e-05 22.2 0.4 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 ORY04596.1 - 6.2e-10 38.4 0.2 1.7e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04596.1 - 1.9e-07 30.8 0.3 0.0051 16.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY04596.1 - 1.4e-06 28.4 0.1 2.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY04596.1 - 0.00011 22.7 0.2 0.0033 18.1 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY04596.1 - 0.00033 21.1 0.3 0.0069 16.9 0.1 2.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY04596.1 - 0.00041 20.5 1.3 0.037 14.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY04596.1 - 0.0017 17.8 0.0 2.2 7.8 0.1 2.5 2 0 0 2 2 2 2 SHNi-TPR DUF1797 PF08796.10 ORY04596.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) Fis1_TPR_C PF14853.6 ORY04596.1 - 0.12 12.5 0.6 2 8.6 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Rod-binding PF10135.9 ORY04596.1 - 6.1 7.5 9.5 0.23 12.0 3.8 1.6 2 0 0 2 2 1 0 Rod binding protein TPR_1 PF00515.28 ORY04597.1 - 4e-13 48.6 0.0 3.7e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04597.1 - 3.1e-12 45.6 0.0 0.00011 22.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY04597.1 - 4.5e-09 36.2 0.1 0.0036 17.3 0.1 3.1 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 ORY04597.1 - 7e-09 36.2 0.0 1.8e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY04597.1 - 4e-08 33.6 0.1 1.8e-07 31.6 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY04597.1 - 9.2e-08 32.0 0.5 0.0076 16.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY04597.1 - 2.4e-07 31.0 0.1 0.0084 16.9 0.1 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY04597.1 - 2.8e-06 27.5 0.3 0.0013 19.0 0.6 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY04597.1 - 3.3e-06 27.2 0.1 2.2e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ORY04597.1 - 4.3e-06 26.3 0.0 0.00069 19.3 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 ORY04597.1 - 0.0019 18.3 0.1 0.92 9.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY04597.1 - 0.016 15.0 0.2 0.65 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF982 PF06169.12 ORY04597.1 - 0.028 14.4 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF982) TPR_20 PF14561.6 ORY04597.1 - 0.041 14.2 0.1 0.057 13.8 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4192 PF13830.6 ORY04597.1 - 0.05 13.7 0.1 0.059 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) HrpB1_HrpK PF09613.10 ORY04597.1 - 0.066 12.8 0.1 0.097 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 ORY04597.1 - 0.085 12.1 0.0 0.23 10.6 0.0 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY04597.1 - 0.19 11.9 1.0 0.69 10.1 0.4 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY04598.1 - 2e-08 33.7 1.1 0.00066 19.4 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY04598.1 - 4.1e-06 26.5 3.9 0.0025 17.8 0.6 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY04598.1 - 0.00087 19.5 0.6 16 5.9 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY04598.1 - 0.0033 17.1 0.5 0.0077 15.9 0.5 1.7 1 1 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 ORY04598.1 - 0.0044 17.6 0.5 0.0056 17.3 0.5 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY04598.1 - 0.014 15.3 0.1 0.033 14.2 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY04598.1 - 0.019 15.2 1.1 0.028 14.6 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat O-FucT PF10250.9 ORY04599.1 - 1.2e-17 64.7 0.1 2.2e-16 60.5 0.1 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PX PF00787.24 ORY04600.1 - 8e-27 93.5 0.1 1.1e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 ORY04601.1 - 1.4e-57 191.6 0.9 3.3e-22 78.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 ORY04602.1 - 5.5e-72 237.8 4.2 4.1e-24 84.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 ORY04602.1 - 0.00031 20.9 0.0 1.1 9.6 0.0 3.1 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Serine_protease PF18405.1 ORY04602.1 - 0.036 13.2 4.6 2.1 7.4 0.1 3.3 1 1 0 3 3 3 0 Gammaproteobacterial serine protease Pertus-S4-tox PF09275.10 ORY04602.1 - 0.12 12.7 1.9 35 4.7 0.1 3.1 3 0 0 3 3 3 0 Pertussis toxin S4 subunit Elongin_A PF06881.11 ORY04603.1 - 9.7e-28 96.8 2.0 1.7e-27 96.0 2.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Alpha-amylase_C PF02806.18 ORY04604.1 - 4.5e-25 88.0 0.0 1.2e-24 86.6 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 ORY04604.1 - 5.2e-18 65.2 0.0 1.1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY04604.1 - 1.1e-15 58.1 0.5 2.3e-13 50.5 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain TP_methylase PF00590.20 ORY04605.1 - 3.3e-23 82.8 0.1 5.2e-23 82.1 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-H2C2_2 PF13465.6 ORY04606.1 - 4.1e-10 39.6 10.4 2.5e-08 34.0 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY04606.1 - 1.2e-08 35.0 11.9 0.00012 22.4 0.2 4.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY04606.1 - 5.7e-06 26.9 8.8 0.013 16.1 0.2 3.7 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY04606.1 - 5.2e-05 23.7 6.4 0.032 15.0 0.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY04606.1 - 7.8e-05 22.6 3.5 0.22 11.6 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf_ZIC PF18366.1 ORY04606.1 - 0.00018 21.5 0.1 0.036 14.2 0.0 3.5 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 ORY04606.1 - 0.00055 20.1 0.2 0.79 9.8 0.1 2.5 2 1 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY04606.1 - 0.0083 16.4 1.4 1.3 9.3 0.0 2.6 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf-met PF12874.7 ORY04606.1 - 0.046 14.1 0.1 8 7.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY04606.1 - 0.2 11.3 1.4 15 5.3 0.0 2.8 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Ribosomal_L21e PF01157.18 ORY04607.1 - 1.1e-47 160.1 7.0 1.4e-47 159.7 5.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e DUF4602 PF15375.6 ORY04608.1 - 6.9e-16 58.8 11.4 9.6e-16 58.3 11.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) UPF0242 PF06785.11 ORY04608.1 - 8.2 6.5 8.6 22 5.1 8.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OSCP PF00213.18 ORY04609.1 - 7.4e-48 162.9 0.8 8.8e-48 162.7 0.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Acyltransferase PF01553.21 ORY04610.1 - 0.00017 21.2 0.0 0.082 12.5 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF2292 PF10055.9 ORY04610.1 - 0.12 12.1 0.1 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Tyrosinase PF00264.20 ORY04611.1 - 6.8e-36 124.6 4.1 1.7e-34 120.0 4.1 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF5347 PF17282.2 ORY04611.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5347) XPC-binding PF09280.11 ORY04612.1 - 0.36 10.6 12.5 3.7 7.4 0.2 4.4 5 0 0 5 5 5 0 XPC-binding domain Arf PF00025.21 ORY04613.1 - 9.1e-80 266.2 0.1 1e-79 266.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY04613.1 - 1.5e-14 53.8 0.0 1.8e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORY04613.1 - 2.5e-14 53.5 0.0 3.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY04613.1 - 2.3e-13 50.1 1.1 1.9e-09 37.2 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY04613.1 - 5.5e-13 48.8 0.0 5.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY04613.1 - 1e-10 41.3 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY04613.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY04613.1 - 0.0073 15.6 0.5 0.018 14.4 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DEAD PF00270.29 ORY04614.1 - 7.8e-47 159.3 0.0 1.2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY04614.1 - 2.4e-24 85.8 0.0 8e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY04614.1 - 6.1e-22 77.6 1.7 1.5e-21 76.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY04614.1 - 1.6e-06 28.2 0.0 8.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 ORY04614.1 - 0.016 15.4 0.7 0.039 14.1 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_19 PF13245.6 ORY04614.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SBF_like PF13593.6 ORY04614.1 - 0.21 10.9 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) CIMR PF00878.18 ORY04615.1 - 1.7e-12 47.6 0.4 2.8e-10 40.4 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 ORY04615.1 - 1.1e-11 44.4 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 ORY04615.1 - 1.4e-06 28.3 0.4 0.002 18.0 0.4 2.7 1 1 0 1 1 1 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 ORY04615.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Pkinase PF00069.25 ORY04616.1 - 1.7e-61 207.9 0.0 6.1e-61 206.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04616.1 - 1.2e-26 93.6 0.4 2.8e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY04616.1 - 0.00071 18.6 0.1 0.0014 17.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY04616.1 - 0.0041 16.5 0.5 0.019 14.3 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 ORY04616.1 - 0.0043 17.0 0.1 0.17 11.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY04616.1 - 0.03 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAF-AH_p_II PF03403.13 ORY04616.1 - 0.071 11.6 0.2 0.3 9.5 0.0 2.1 2 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Pkinase_C PF00433.24 ORY04616.1 - 0.12 13.1 0.9 0.36 11.6 0.9 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Serpin PF00079.20 ORY04617.1 - 2.4e-64 218.0 0.0 3.5e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PAP_assoc PF03828.19 ORY04618.1 - 8.6e-19 67.5 0.5 2.3e-18 66.1 0.5 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY04618.1 - 5.1e-06 26.7 0.0 9.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY04618.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TFIIF_alpha PF05793.12 ORY04619.1 - 2.6e-30 105.5 41.2 3.5e-28 98.5 41.3 2.8 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 ORY04619.1 - 0.01 15.3 27.6 0.019 14.4 27.6 1.4 1 0 0 1 1 1 0 SDA1 FlaG PF03646.15 ORY04619.1 - 5.3 7.3 11.6 0.6 10.3 4.5 2.6 2 0 0 2 2 2 0 FlaG protein PH PF00169.29 ORY04620.1 - 4.6e-37 126.7 8.1 7.6e-19 68.2 0.3 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 ORY04620.1 - 1e-14 54.8 13.1 5.5e-07 30.0 2.8 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 ORY04620.1 - 2.3e-12 46.9 2.9 1.3e-05 25.2 0.7 2.4 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 ORY04620.1 - 2.8e-09 37.1 7.8 0.00045 20.4 2.1 2.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 ORY04620.1 - 8.4e-09 35.8 9.0 6.7e-05 23.2 2.5 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 ORY04620.1 - 0.0019 18.5 0.1 1.8 8.9 0.1 2.4 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_15 PF17339.2 ORY04620.1 - 0.01 15.8 3.7 0.42 10.5 0.9 2.4 2 0 0 2 2 2 2 PH domain BCL_N PF04714.13 ORY04620.1 - 0.015 15.3 3.6 1.7 8.8 0.5 2.5 2 0 0 2 2 2 0 BCL7, N-terminal conserver region DUF3134 PF11332.8 ORY04620.1 - 0.016 15.5 2.5 0.2 12.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) PH_13 PF16652.5 ORY04620.1 - 0.045 13.6 0.4 4.6 7.0 0.1 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain BHD_1 PF10403.9 ORY04620.1 - 0.069 13.0 0.2 3.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 Myosin_TH1 PF06017.13 ORY04620.1 - 0.077 12.7 0.2 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding PNP_UDP_1 PF01048.20 ORY04622.1 - 1.9e-35 122.2 0.0 2.6e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Actin PF00022.19 ORY04623.1 - 1.6e-36 125.8 0.0 5.4e-36 124.1 0.0 2.0 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 ORY04623.1 - 2.6e-20 73.0 0.8 2.2e-11 43.6 0.0 2.8 3 0 0 3 3 3 2 Putative actin-like family MreB_Mbl PF06723.13 ORY04623.1 - 1.6e-05 23.9 0.2 0.023 13.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORY04623.1 - 0.081 13.3 0.0 0.85 10.1 0.0 2.4 2 1 0 2 2 2 0 Cell division protein FtsA Bromodomain PF00439.25 ORY04623.1 - 0.14 12.2 0.1 3.5 7.7 0.0 2.8 3 0 0 3 3 3 0 Bromodomain Myc_N PF01056.18 ORY04623.1 - 1.4 8.7 9.9 7.2 6.4 6.1 2.2 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.6 ORY04623.1 - 3.4 7.3 7.4 7.6 6.2 1.5 2.4 2 0 0 2 2 2 0 FAM176 family DUF3381 PF11861.8 ORY04623.1 - 7 6.4 14.8 0.51 10.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RNase_H2_suC PF08615.11 ORY04624.1 - 2.1e-15 57.1 0.4 1.7e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LRR_4 PF12799.7 ORY04625.1 - 4.3e-44 147.8 60.0 2.4e-09 37.3 2.4 7.4 2 1 8 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY04625.1 - 4.6e-21 74.4 36.6 5.9e-06 26.0 2.5 6.2 4 2 0 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 ORY04625.1 - 2.1e-19 69.7 19.6 8.1e-09 35.2 6.6 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 ORY04625.1 - 2.8e-06 27.1 26.2 4.7 8.2 0.6 9.7 9 1 0 9 9 9 3 Leucine Rich Repeat CSN4_RPN5_eIF3a PF18420.1 ORY04625.1 - 0.012 15.7 0.1 0.038 14.2 0.1 1.8 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain UB2H PF14814.6 ORY04625.1 - 0.017 15.1 3.6 46 4.1 0.0 5.4 2 2 3 6 6 6 0 Bifunctional transglycosylase second domain LRR_6 PF13516.6 ORY04625.1 - 0.071 13.2 32.5 0.69 10.1 0.2 8.3 10 1 1 11 11 11 0 Leucine Rich repeat LRR_5 PF13306.6 ORY04625.1 - 0.37 10.7 7.3 0.96 9.4 0.8 2.9 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Nop10p PF04135.12 ORY04626.1 - 4.2e-24 84.3 0.4 4.8e-24 84.2 0.4 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Gemin6 PF06372.12 ORY04627.1 - 2.4e-12 46.7 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Gemin6 protein SM-ATX PF14438.6 ORY04627.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain AD PF09793.9 ORY04627.1 - 0.13 12.4 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Anticodon-binding domain Mito_carr PF00153.27 ORY04628.1 - 6.5e-20 70.9 0.1 2.2e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Flavin_Reduct PF01613.18 ORY04629.1 - 5e-41 140.3 0.6 6.9e-41 139.9 0.6 1.2 1 0 0 1 1 1 1 Flavin reductase like domain TPR_2 PF07719.17 ORY04630.1 - 1.5e-06 27.9 4.9 1.3 9.3 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY04630.1 - 0.77 10.1 11.5 2.2 8.6 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY04630.1 - 2 8.7 7.5 27 5.1 0.5 4.3 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 GCV_H PF01597.19 ORY04631.1 - 1.3e-43 147.8 0.2 1.5e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein FTR_C PF02741.15 ORY04631.1 - 0.076 13.0 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 FTR, proximal lobe Serpin PF00079.20 ORY04632.1 - 7.7e-74 249.2 0.0 8.6e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) GST_N_5 PF18485.1 ORY04632.1 - 0.093 13.1 0.5 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ssl1 PF04056.14 ORY04633.1 - 2.6e-80 268.8 0.0 3.3e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 ORY04633.1 - 1.8e-18 66.5 11.6 1.8e-18 66.5 11.6 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 ORY04633.1 - 6.2e-12 46.1 0.0 1.5e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 ORY04633.1 - 0.0093 15.5 5.2 0.017 14.7 5.2 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF4428 PF14471.6 ORY04633.1 - 0.063 13.2 4.5 0.29 11.1 4.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Tim54 PF11711.8 ORY04633.1 - 0.17 10.6 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ABC_tran PF00005.27 ORY04634.1 - 2.7e-47 160.7 1.9 2.6e-23 83.1 0.0 3.1 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY04634.1 - 1.1e-22 79.9 7.0 1.1e-22 79.9 7.0 2.6 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 ORY04634.1 - 7.6e-12 45.1 0.0 0.0013 18.2 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY04634.1 - 8.6e-11 42.2 12.0 0.012 15.4 0.2 5.1 3 2 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY04634.1 - 8.6e-07 29.0 0.0 0.068 13.3 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY04634.1 - 9.5e-07 28.9 0.0 0.009 15.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY04634.1 - 1.6e-06 28.6 0.0 0.059 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY04634.1 - 4e-06 26.5 1.1 0.021 14.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 ORY04634.1 - 7.5e-06 26.3 1.3 0.19 12.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 ORY04634.1 - 1.2e-05 25.7 0.1 0.051 13.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY04634.1 - 2.2e-05 25.0 2.4 0.12 12.9 0.0 3.6 4 1 0 4 4 3 2 AAA domain AAA_24 PF13479.6 ORY04634.1 - 3.7e-05 23.5 0.0 0.36 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORY04634.1 - 0.00019 21.2 7.2 0.11 12.2 0.2 4.1 4 1 0 4 4 4 2 AAA ATPase domain AAA_27 PF13514.6 ORY04634.1 - 0.00083 19.0 0.2 0.31 10.6 0.0 3.6 3 1 1 4 4 4 1 AAA domain NACHT PF05729.12 ORY04634.1 - 0.0011 18.9 0.0 0.97 9.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 ORY04634.1 - 0.0015 18.7 1.1 1.2 9.3 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 ORY04634.1 - 0.0016 18.2 0.0 0.093 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORY04634.1 - 0.0023 18.3 0.1 1.6 9.1 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_23 PF13476.6 ORY04634.1 - 0.006 17.1 21.8 0.2 12.1 0.0 5.0 5 0 0 5 5 5 2 AAA domain MeaB PF03308.16 ORY04634.1 - 0.0091 15.0 0.3 4.5 6.2 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 ORY04634.1 - 0.012 15.8 1.0 0.31 11.3 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 ORY04634.1 - 0.013 15.5 7.2 0.64 10.1 0.0 3.7 3 1 0 4 4 4 0 Dynamin family AAA_14 PF13173.6 ORY04634.1 - 0.015 15.3 0.1 7.9 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY04634.1 - 0.017 15.5 2.1 9.9 6.6 0.0 3.7 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY04634.1 - 0.028 14.4 0.1 9.3 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ORY04634.1 - 0.028 13.6 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 ORY04634.1 - 0.044 13.7 1.1 8 6.3 0.0 3.2 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 ORY04634.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 ORY04634.1 - 0.082 13.1 0.1 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORY04634.1 - 0.1 12.1 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 ORY04634.1 - 0.37 10.5 1.1 6.7 6.4 0.1 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Tom37_C PF11801.8 ORY04634.1 - 0.43 10.5 5.5 0.16 11.9 1.5 2.2 2 1 0 2 2 2 0 Tom37 C-terminal domain Cytidylate_kin PF02224.18 ORY04634.1 - 0.67 9.6 0.0 0.67 9.6 0.0 3.0 4 0 0 4 4 4 0 Cytidylate kinase DUF87 PF01935.17 ORY04634.1 - 1.2 9.2 11.4 4.5 7.3 0.0 4.1 4 1 1 5 5 5 0 Helicase HerA, central domain GATA PF00320.27 ORY04635.1 - 7.4e-13 47.9 6.9 1.3e-12 47.1 6.9 1.4 1 0 0 1 1 1 1 GATA zinc finger Nucleos_tra2_C PF07662.13 ORY04636.1 - 1.4e-71 240.6 6.8 4.7e-71 238.9 6.8 1.9 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04636.1 - 9.4e-23 80.6 2.3 9.4e-23 80.6 2.3 3.7 3 1 1 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.13 ORY04637.1 - 1.1e-56 191.9 13.6 1.6e-40 139.2 2.7 3.1 2 1 1 3 3 3 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04637.1 - 3.8e-22 78.7 3.5 3.8e-22 78.7 3.5 3.4 4 1 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus LMF1 PF06762.14 ORY04637.1 - 7.6 5.5 12.0 1.7e+02 1.1 11.8 2.6 1 1 0 1 1 1 0 Lipase maturation factor Nucleos_tra2_C PF07662.13 ORY04638.1 - 1.4e-70 237.3 6.4 1.4e-70 237.3 6.4 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04638.1 - 3.9e-22 78.6 3.5 3.9e-22 78.6 3.5 4.4 4 1 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.13 ORY04639.1 - 8.2e-31 107.5 0.2 8.2e-31 107.5 0.2 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04639.1 - 2.6e-22 79.2 3.5 2.6e-22 79.2 3.5 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.13 ORY04640.1 - 1.6e-71 240.4 3.7 1.6e-71 240.4 3.7 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04640.1 - 3.7e-22 78.7 1.9 3.7e-22 78.7 1.9 3.5 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.13 ORY04641.1 - 2.6e-72 243.0 7.5 2.6e-72 243.0 7.5 2.6 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04641.1 - 1.7e-23 83.0 1.6 1.7e-23 83.0 1.6 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Herpes_UL49_5 PF05702.11 ORY04641.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein Nucleos_tra2_C PF07662.13 ORY04642.1 - 1.1e-74 250.7 6.9 1.1e-74 250.7 6.9 2.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY04642.1 - 1.1e-24 86.8 1.8 1.1e-24 86.8 1.8 3.7 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Herpes_UL49_5 PF05702.11 ORY04642.1 - 0.017 15.2 0.0 0.092 12.8 0.0 2.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Glyco_hydro_18 PF00704.28 ORY04643.1 - 2.8e-24 86.4 2.1 2.8e-24 86.4 2.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORY04643.1 - 6.5e-07 29.6 29.2 0.00041 20.8 9.8 3.8 3 0 0 3 3 3 2 Carbohydrate binding domain Hamartin PF04388.12 ORY04643.1 - 0.83 8.2 6.5 1.1 7.9 6.5 1.1 1 0 0 1 1 1 0 Hamartin protein FTR1 PF03239.14 ORY04644.1 - 8.8e-71 238.6 12.0 1.1e-70 238.3 12.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Peptidase_U4 PF03419.13 ORY04644.1 - 0.00015 21.1 4.5 0.00015 21.1 4.5 2.0 2 0 0 2 2 2 1 Sporulation factor SpoIIGA ESSS PF10183.9 ORY04644.1 - 0.43 10.8 2.1 2.2 8.5 0.0 2.7 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cu-oxidase_2 PF07731.14 ORY04645.1 - 2.4e-45 153.7 9.4 1.5e-42 144.6 1.6 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY04645.1 - 8.8e-36 122.5 9.8 1.3e-34 118.8 0.8 3.8 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY04645.1 - 2.1e-33 115.7 2.6 1.5e-32 112.9 0.2 2.9 3 0 0 3 3 3 1 Multicopper oxidase Peptidase_M30 PF10460.9 ORY04645.1 - 0.04 12.9 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase M30 NAP PF00956.18 ORY04646.1 - 1.7e-87 293.0 15.9 2.5e-87 292.5 15.9 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) TcpS PF17456.2 ORY04646.1 - 0.81 9.7 4.3 0.62 10.1 1.6 2.1 2 1 1 3 3 3 0 Toxin-coregulated pilus protein S Cwf_Cwc_15 PF04889.12 ORY04646.1 - 6 6.5 16.7 0.34 10.6 9.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MRP-S34 PF16053.5 ORY04647.1 - 4.1e-12 45.9 0.7 8e-12 44.9 0.7 1.4 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S34 Gly_acyl_tr_C PF08444.10 ORY04648.1 - 0.0013 18.9 0.2 0.0052 17.0 0.1 2.0 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FR47 PF08445.10 ORY04648.1 - 0.16 12.0 0.1 0.61 10.1 0.1 1.9 1 1 0 1 1 1 0 FR47-like protein NAD_binding_1 PF00175.21 ORY04649.1 - 5.7e-25 88.1 0.0 1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY04649.1 - 1e-19 70.7 0.0 1.7e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY04649.1 - 2.5e-07 30.9 0.0 1.4e-05 25.2 0.0 2.5 1 1 1 2 2 2 1 Ferric reductase NAD binding domain TIM21 PF08294.11 ORY04649.1 - 0.039 13.8 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 TIM21 zinc_ribbon_15 PF17032.5 ORY04706.1 - 4.3e-12 46.6 1.6 5.3e-12 46.3 1.6 1.1 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 ORY04706.1 - 0.00078 19.4 8.5 0.0012 18.8 3.1 2.3 2 0 0 2 2 2 1 Double zinc ribbon HypA PF01155.19 ORY04706.1 - 0.0028 17.7 6.4 0.012 15.6 2.6 2.3 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 ORY04706.1 - 0.0053 16.4 6.2 0.0053 16.4 6.2 2.9 3 0 0 3 3 3 1 zinc-ribbon domain zf-CHY PF05495.12 ORY04706.1 - 0.028 14.9 6.6 0.91 10.1 6.6 2.3 1 1 0 1 1 1 0 CHY zinc finger Cript PF10235.9 ORY04706.1 - 0.061 13.9 0.8 0.061 13.9 0.8 1.9 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT NOB1_Zn_bind PF08772.11 ORY04706.1 - 0.091 12.9 1.6 0.091 12.9 1.6 2.2 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_ribbon_SprT PF17283.2 ORY04706.1 - 0.19 11.7 12.0 0.72 9.8 0.1 3.6 2 2 0 2 2 2 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 ORY04706.1 - 0.19 11.7 10.8 12 5.9 0.3 3.3 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_12 PF11331.8 ORY04706.1 - 0.55 10.1 5.5 0.21 11.4 1.4 2.4 2 1 0 2 2 2 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 ORY04706.1 - 0.77 10.3 8.5 4.4 7.9 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain DUF4187 PF13821.6 ORY04706.1 - 0.78 9.6 6.2 6.7 6.6 6.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4187) Elf1 PF05129.13 ORY04706.1 - 0.8 9.8 5.7 2.5 8.2 0.7 2.6 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 ORY04706.1 - 1 9.4 0.0 1 9.4 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ORY04706.1 - 1.2 9.4 13.3 2.3 8.4 4.9 3.4 3 1 0 3 3 3 0 Zinc ribbon domain Cys_rich_CPCC PF14206.6 ORY04706.1 - 1.9 8.4 6.4 9.9 6.1 0.0 2.6 3 0 0 3 3 3 0 Cysteine-rich CPCC zf-LITAF-like PF10601.9 ORY04706.1 - 1.9 8.8 10.3 0.89 9.9 0.8 3.3 2 2 1 3 3 3 0 LITAF-like zinc ribbon domain C1_2 PF03107.16 ORY04706.1 - 5.3 7.4 14.6 15 6.0 8.5 3.0 2 1 0 2 2 2 0 C1 domain Nudix_N_2 PF14803.6 ORY04706.1 - 6.8 6.7 16.0 14 5.7 5.0 3.8 3 1 1 4 4 4 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 ORY04706.1 - 9 6.3 11.1 2.8 7.9 2.2 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF3384 PF11864.8 ORY04707.1 - 1.1e-89 301.6 8.6 1.1e-89 301.6 8.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 ORY04707.1 - 3.9e-51 173.3 0.1 7.9e-51 172.2 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 ORY04707.1 - 6.8e-49 166.8 1.2 1.6e-44 152.5 0.2 2.8 2 1 0 2 2 2 2 Tuberin DUF1206 PF06724.11 ORY04707.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) PIN_4 PF13638.6 ORY04708.1 - 1.4e-13 51.3 0.0 5.1e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 PIN domain PIN_9 PF18477.1 ORY04708.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 PIN like domain Yippee-Mis18 PF03226.14 ORY04709.1 - 1.4e-15 57.3 0.4 1.7e-15 57.1 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORY04709.1 - 0.058 13.6 1.4 0.11 12.7 1.4 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I LIM PF00412.22 ORY04709.1 - 0.084 13.1 1.7 2.2 8.6 0.4 2.2 2 0 0 2 2 2 0 LIM domain EAP30 PF04157.16 ORY04710.1 - 2.5e-37 128.4 0.1 3.7e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 ORY04710.1 - 2.4e-22 78.9 0.0 5e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 ORY04710.1 - 0.016 14.5 14.3 0.036 13.4 1.6 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others GRAM PF02893.20 ORY04710.1 - 0.064 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 GRAM domain zf-Sec23_Sec24 PF04810.15 ORY04710.1 - 0.16 12.0 13.3 2.7 8.1 1.3 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 ORY04710.1 - 0.52 9.7 13.6 0.15 11.4 6.9 3.0 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ACOX PF01756.19 ORY04711.1 - 3.5e-48 163.5 0.0 6.4e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY04711.1 - 3.1e-21 75.4 0.0 6.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORY04711.1 - 4.2e-18 66.1 0.0 8.4e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORY04711.1 - 1.4e-07 31.9 0.2 1.4e-05 25.3 0.1 2.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Sulfotransfer_4 PF17784.1 ORY04711.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain ERAP1_C PF11838.8 ORY04712.1 - 2.9e-90 303.0 0.9 1e-88 298.0 0.2 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 ORY04712.1 - 7.9e-89 296.9 0.2 1.3e-88 296.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY04712.1 - 1e-56 192.1 3.6 1.5e-56 191.6 1.6 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 ORY04712.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) CTC1 PF15489.6 ORY04713.1 - 3.7e-23 81.1 0.3 5.7e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 CST, telomere maintenance, complex subunit CTC1 CTC1_2 PF15491.6 ORY04713.1 - 0.00028 20.3 0.0 0.00092 18.6 0.0 1.8 2 0 0 2 2 2 1 CST, telomere maintenance, complex subunit CTC1 Hydrolase_4 PF12146.8 ORY04714.1 - 1.1e-45 155.8 0.0 1.3e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY04714.1 - 2.2e-15 57.0 0.1 3.9e-11 43.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY04714.1 - 2e-11 44.9 0.1 2.7e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY04714.1 - 2.6e-11 43.4 0.2 4e-05 23.2 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY04714.1 - 1.2e-06 28.3 0.0 0.00017 21.3 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORY04714.1 - 9.3e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 ORY04714.1 - 0.022 14.3 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ORY04714.1 - 0.084 12.6 0.1 5.3 6.8 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family UPF0227 PF05728.12 ORY04714.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Acyl_transf_2 PF02273.15 ORY04714.1 - 0.15 11.3 0.0 7.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Acyl transferase DDHD PF02862.17 ORY04716.1 - 9.2e-32 111.0 0.1 2.4e-31 109.7 0.1 1.7 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.14 ORY04716.1 - 0.031 13.8 0.0 0.086 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PTR2 PF00854.21 ORY04717.1 - 1e-54 185.9 0.2 7.5e-53 179.8 0.2 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY04717.1 - 1.2e-13 50.7 3.4 5.6e-07 28.8 0.6 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY04717.1 - 0.011 14.6 12.2 0.071 12.0 0.4 2.8 2 1 1 3 3 3 0 Sugar (and other) transporter ToxS PF17323.2 ORY04718.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS DUF4131 PF13567.6 ORY04719.1 - 0.002 17.8 0.5 0.0025 17.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF3290 PF11694.8 ORY04719.1 - 0.011 15.8 0.1 0.014 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2142 PF09913.9 ORY04719.1 - 0.031 13.1 0.6 0.039 12.8 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Ribosomal_S13 PF00416.22 ORY04720.1 - 2.2e-56 189.7 2.5 2.6e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORY04720.1 - 0.0059 15.4 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 ORY04720.1 - 0.011 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP28 PF10252.9 ORY04720.1 - 0.12 12.8 0.4 0.26 11.8 0.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 MIP PF00230.20 ORY04721.1 - 8.7e-57 192.4 9.7 1.1e-56 192.1 9.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein nlz1 PF12402.8 ORY04721.1 - 0.028 14.9 0.1 0.088 13.2 0.1 1.9 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 DUF4516 PF14990.6 ORY04721.1 - 0.61 9.8 1.8 25 4.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) WSC PF01822.19 ORY04722.1 - 1.3e-13 51.0 10.1 2.3e-13 50.2 10.1 1.4 1 0 0 1 1 1 1 WSC domain EamA PF00892.20 ORY04723.1 - 3.7e-26 91.9 34.8 3.7e-14 53.1 14.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ORY04723.1 - 0.00018 20.8 3.7 0.14 11.3 0.5 2.2 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 ORY04723.1 - 0.044 13.0 0.1 0.044 13.0 0.1 1.7 2 1 0 2 2 2 0 Nucleotide-sugar transporter TPT PF03151.16 ORY04723.1 - 0.062 12.6 6.4 0.13 11.6 0.2 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family IF-2B PF01008.17 ORY04724.1 - 8.1e-71 238.5 0.6 9.5e-71 238.3 0.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CX9C PF16860.5 ORY04725.1 - 1.5e-19 69.7 14.3 1.1e-15 57.3 4.1 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 ORY04725.1 - 3.6e-06 27.0 12.4 0.0066 16.6 3.9 2.4 2 0 0 2 2 2 2 CHCH domain MTCP1 PF08991.10 ORY04725.1 - 0.00026 21.1 2.3 0.00026 21.1 2.3 2.1 1 1 1 2 2 2 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 ORY04725.1 - 0.008 16.5 10.6 0.23 11.8 8.7 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 ORY04725.1 - 0.013 15.5 9.8 0.083 12.9 2.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TPR_17 PF13431.6 ORY04725.1 - 0.045 14.1 0.6 0.13 12.7 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PDH PF02153.17 ORY04725.1 - 0.062 12.3 0.0 0.095 11.7 0.0 1.4 1 1 0 1 1 1 0 Prephenate dehydrogenase GCK PF07802.11 ORY04725.1 - 0.58 10.6 8.9 1.1 9.7 1.3 2.3 1 1 1 2 2 2 0 GCK domain zf-CCHC PF00098.23 ORY04726.1 - 0.0023 17.9 2.4 0.0056 16.7 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle HTH_23 PF13384.6 ORY04726.1 - 0.047 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 ORY04726.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ORY04726.1 - 0.14 12.2 0.2 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GPI-anchored PF10342.9 ORY04727.1 - 2.5e-11 44.2 0.0 3e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2793 PF10983.8 ORY04727.1 - 0.048 13.5 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) SMC_N PF02463.19 ORY04728.1 - 3.3e-52 177.1 53.9 1.5e-51 175.0 53.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY04728.1 - 8.8e-22 77.6 0.9 2.7e-21 76.1 0.9 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 ORY04728.1 - 1.7e-11 45.0 23.0 1.7e-11 45.0 23.0 7.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 ORY04728.1 - 5.2e-10 39.6 10.4 2.6e-05 24.2 0.2 3.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY04728.1 - 6.2e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lebercilin PF15619.6 ORY04728.1 - 0.0011 18.7 16.8 0.0011 18.7 16.8 6.5 2 2 4 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 ORY04728.1 - 0.0036 16.2 26.0 0.0036 16.2 26.0 7.2 2 2 5 7 7 7 3 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 ORY04728.1 - 0.033 14.6 0.3 0.033 14.6 0.3 10.2 7 2 3 10 10 10 0 Centrosome microtubule-binding domain of Cep57 AAA_15 PF13175.6 ORY04728.1 - 0.057 13.1 94.7 0.0091 15.7 41.9 4.7 2 2 1 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 ORY04728.1 - 0.48 10.9 0.0 0.48 10.9 0.0 7.1 3 2 1 4 4 4 0 ABC transporter UTP25 PF06862.12 ORY04729.1 - 3.9e-166 553.5 12.7 1.3e-165 551.7 12.7 1.7 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 ORY04729.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase LRR_6 PF13516.6 ORY04730.1 - 1.8e-08 33.8 6.0 1.6 9.0 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat F-box-like PF12937.7 ORY04730.1 - 3.3e-08 33.3 0.0 1.5e-07 31.2 0.0 2.3 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY04730.1 - 0.0078 16.6 13.8 7.5 7.5 0.1 6.8 5 1 0 5 5 5 2 Leucine Rich Repeat Pentapeptide_4 PF13599.6 ORY04730.1 - 0.025 14.7 0.4 0.29 11.3 0.0 2.7 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Septin PF00735.18 ORY04731.1 - 2.2e-69 233.8 0.0 2.6e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY04731.1 - 1.2e-07 31.8 0.0 2.2e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORY04731.1 - 3.2e-05 23.4 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.27 ORY04731.1 - 3.8e-05 23.3 0.0 0.083 12.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORY04731.1 - 8.6e-05 22.0 0.0 0.00019 20.8 0.0 1.6 1 1 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 ORY04731.1 - 0.0002 21.8 0.0 0.00039 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY04731.1 - 0.00053 19.9 0.8 0.0015 18.5 0.3 2.0 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORY04731.1 - 0.00074 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORY04731.1 - 0.0012 19.0 2.0 0.31 11.1 2.4 2.6 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 ORY04731.1 - 0.0023 18.5 0.0 0.003 18.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter IIGP PF05049.13 ORY04731.1 - 0.003 16.7 0.0 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 ORY04731.1 - 0.003 17.1 0.3 0.007 15.9 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Ras PF00071.22 ORY04731.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 ORY04731.1 - 0.006 16.9 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY04731.1 - 0.0095 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase G-alpha PF00503.20 ORY04731.1 - 0.02 14.1 0.0 0.024 13.8 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 ORY04731.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 ORY04731.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 NACHT domain TniB PF05621.11 ORY04731.1 - 0.05 13.0 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 ORY04731.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF3987 PF13148.6 ORY04731.1 - 0.085 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_33 PF13671.6 ORY04731.1 - 0.098 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY04731.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ORY04731.1 - 0.15 11.8 0.5 0.3 10.8 0.1 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 ORY04731.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Gtr1_RagA PF04670.12 ORY04731.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region zf-CSL PF05207.13 ORY04732.1 - 5.3e-24 83.7 1.9 7.4e-24 83.3 1.9 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 ORY04732.1 - 0.036 14.2 0.1 0.077 13.2 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain zf-RING_4 PF14570.6 ORY04732.1 - 0.1 12.4 2.6 0.2 11.5 2.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AstE_AspA PF04952.14 ORY04733.1 - 8.8e-47 159.6 0.0 1.1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family SPX PF03105.19 ORY04733.1 - 1.7e-17 64.5 15.2 3.3e-08 33.9 1.2 3.1 1 1 2 3 3 3 3 SPX domain Snf7 PF03357.21 ORY04734.1 - 2.6e-39 134.6 18.7 2.6e-39 134.6 18.7 1.4 2 0 0 2 2 2 1 Snf7 Herpes_U44 PF04533.13 ORY04734.1 - 2.4 7.7 7.4 6.9 6.2 7.4 1.8 1 1 0 1 1 1 0 Herpes virus U44 protein AAA_11 PF13086.6 ORY04735.1 - 4.5e-76 256.1 2.2 6.8e-76 255.5 2.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY04735.1 - 3.5e-64 216.1 0.0 8.4e-64 214.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY04735.1 - 3.1e-12 46.6 0.0 6e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ORY04735.1 - 1.1e-09 38.7 0.0 1.2e-08 35.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 ORY04735.1 - 3.1e-07 30.2 1.7 9.2e-05 22.1 1.7 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 ORY04735.1 - 2.7e-06 27.3 0.1 0.016 14.9 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ORY04735.1 - 3.4e-05 23.9 0.1 0.00018 21.5 0.1 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 ORY04735.1 - 0.00074 19.4 0.2 0.095 12.5 0.0 2.9 3 0 0 3 3 3 1 Helicase Vps54_N PF10475.9 ORY04735.1 - 0.0032 16.8 1.6 0.0058 16.0 1.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex AAA_25 PF13481.6 ORY04735.1 - 0.012 15.2 0.2 0.055 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2675 PF11247.8 ORY04735.1 - 0.013 15.6 0.0 0.07 13.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) AAA_22 PF13401.6 ORY04735.1 - 0.016 15.5 0.4 0.092 13.0 0.1 2.5 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 ORY04735.1 - 0.066 13.6 0.3 0.19 12.2 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF247 PF03140.15 ORY04735.1 - 0.076 12.2 0.6 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Plant protein of unknown function T2SSE PF00437.20 ORY04735.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Med15_fungi PF05397.12 ORY04735.1 - 0.17 12.2 0.8 0.36 11.1 0.8 1.5 1 0 0 1 1 1 0 Mediator complex subunit 15 SbsC_C PF18058.1 ORY04735.1 - 0.19 11.9 5.6 0.38 11.0 5.6 1.4 1 0 0 1 1 1 0 SbsC C-terminal domain DUF4164 PF13747.6 ORY04735.1 - 0.29 11.4 3.7 0.97 9.8 3.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Ribosomal_L4 PF00573.22 ORY04736.1 - 5.9e-61 205.5 0.4 6.8e-61 205.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Tmemb_14 PF03647.13 ORY04737.1 - 1.2e-24 86.8 9.7 1.4e-24 86.7 9.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C JIP_LZII PF16471.5 ORY04738.1 - 0.0034 17.5 2.5 0.0034 17.5 2.5 6.7 4 2 3 7 7 7 1 JNK-interacting protein leucine zipper II Peptidase_S8 PF00082.22 ORY04739.1 - 2.5e-15 56.5 5.5 3e-07 30.0 0.1 2.7 1 1 1 2 2 2 2 Subtilase family zf-RING_2 PF13639.6 ORY04740.1 - 1.6e-12 47.5 6.5 2.1e-12 47.2 6.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY04740.1 - 1.8e-09 37.3 5.7 2.5e-09 36.8 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY04740.1 - 3.6e-08 33.6 10.3 7.4e-07 29.4 10.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY04740.1 - 7.7e-08 32.1 4.5 1e-07 31.7 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY04740.1 - 9e-08 32.0 1.1 9e-08 32.0 1.1 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY04740.1 - 1.1e-07 31.4 0.9 1.1e-07 31.4 0.9 1.5 2 0 0 2 2 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 ORY04740.1 - 9.9e-06 25.3 6.9 3e-05 23.8 7.1 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY04740.1 - 2.9e-05 23.8 5.0 4.8e-05 23.1 5.0 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY04740.1 - 4.9e-05 23.2 5.3 0.00023 21.0 5.5 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY04740.1 - 0.00024 21.1 4.9 0.0014 18.6 4.9 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY04740.1 - 0.00031 20.8 4.7 0.0027 17.9 4.7 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY04740.1 - 0.0023 17.5 5.6 0.0053 16.4 5.6 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY04740.1 - 0.0042 17.2 3.5 0.011 15.9 3.5 1.7 1 1 0 1 1 1 1 RING-variant domain zf-RING_9 PF13901.6 ORY04740.1 - 0.013 15.5 0.3 0.014 15.4 0.3 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-Nse PF11789.8 ORY04740.1 - 0.018 14.9 2.4 0.027 14.3 2.4 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_2 PF03107.16 ORY04740.1 - 0.076 13.3 0.3 0.076 13.3 0.3 1.8 2 0 0 2 2 2 0 C1 domain zf-Di19 PF05605.12 ORY04740.1 - 0.13 12.5 2.2 7.2 7.0 0.2 2.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 ORY04740.1 - 0.28 11.1 6.6 3.7 7.5 6.4 2.2 1 1 1 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 ORY04740.1 - 0.37 10.6 5.8 0.56 10.0 5.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 ORY04740.1 - 0.49 10.5 6.8 1.7 8.7 6.9 2.0 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 ORY04740.1 - 2.4 8.4 7.2 20 5.4 7.5 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 ORY04741.1 - 5.9e-14 52.1 8.2 1e-13 51.4 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY04741.1 - 3.8e-09 36.2 8.7 6.8e-09 35.4 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY04741.1 - 7.4e-09 35.8 10.6 4.7e-08 33.2 10.5 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY04741.1 - 2.1e-08 33.9 8.0 3.8e-08 33.1 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY04741.1 - 7.5e-08 32.3 3.4 1.7e-07 31.2 2.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY04741.1 - 1.1e-07 31.5 7.4 1.1e-07 31.5 7.4 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 ORY04741.1 - 9.7e-07 28.6 4.1 1.9e-06 27.6 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY04741.1 - 6.8e-06 25.8 6.3 7.1e-06 25.8 4.7 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY04741.1 - 9.9e-06 25.4 5.9 1.6e-05 24.7 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY04741.1 - 6.7e-05 22.9 6.7 0.00011 22.2 6.7 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 ORY04741.1 - 0.0026 17.8 4.2 0.0076 16.4 4.2 1.8 1 1 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 ORY04741.1 - 0.0088 15.6 8.0 0.014 15.0 8.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 ORY04741.1 - 0.014 15.2 3.7 0.021 14.6 3.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY04741.1 - 0.021 15.0 7.3 0.11 12.7 6.5 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 ORY04741.1 - 0.046 13.9 6.9 0.23 11.7 6.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 ORY04741.1 - 0.057 13.4 9.5 0.98 9.4 5.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 ORY04741.1 - 0.12 12.3 4.2 0.22 11.4 4.2 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 ORY04741.1 - 3.7 7.5 11.5 1.7 8.6 7.5 2.5 3 1 1 4 4 4 0 PHD-finger Sec1 PF00995.23 ORY04742.1 - 1.8e-122 410.5 6.6 2.1e-122 410.2 6.6 1.1 1 0 0 1 1 1 1 Sec1 family Abhydrolase_1 PF00561.20 ORY04743.1 - 7.3e-17 61.8 0.0 2.6e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY04743.1 - 2.8e-14 53.0 0.0 7.8e-14 51.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY04743.1 - 8.6e-12 46.1 0.0 1.1e-11 45.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY04743.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 ORY04743.1 - 0.00017 21.6 0.1 0.002 18.1 0.1 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ORY04743.1 - 0.0051 16.3 0.0 3.7 6.9 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ORY04743.1 - 0.0066 16.0 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family UPF0227 PF05728.12 ORY04743.1 - 0.032 14.2 0.0 1.4 8.8 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 ORY04743.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 ORY04743.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 ORY04743.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Sod_Cu PF00080.20 ORY04744.1 - 1.5e-52 177.5 4.8 1.7e-52 177.3 4.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 ORY04744.1 - 0.005 17.8 0.7 0.0067 17.4 0.7 1.3 1 0 0 1 1 1 1 CHRD domain Leo1 PF04004.13 ORY04745.1 - 2.7e-49 167.2 0.7 2.7e-49 167.2 0.7 3.5 3 1 1 4 4 4 1 Leo1-like protein Med10 PF09748.9 ORY04746.1 - 1.1e-31 109.3 0.0 1.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Cytochrome_CBB3 PF13442.6 ORY04746.1 - 0.14 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III VWA_2 PF13519.6 ORY04793.1 - 0.013 16.1 0.0 0.049 14.3 0.0 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Amidohydro_1 PF01979.20 ORY04794.1 - 1.2e-22 80.7 0.0 2e-22 80.0 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY04794.1 - 6.8e-09 35.7 0.8 1.5e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glucosamine_iso PF01182.20 ORY04795.1 - 3.3e-18 66.4 0.0 5.4e-18 65.7 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CK_II_beta PF01214.18 ORY04796.1 - 3.3e-76 255.2 0.1 4.1e-76 254.9 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Sugar_tr PF00083.24 ORY04797.1 - 7.2e-38 130.6 5.0 9e-38 130.3 5.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY04797.1 - 4.7e-24 85.0 11.6 5.7e-24 84.7 11.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY04797.1 - 5.3e-05 22.0 11.1 5.9e-05 21.8 9.8 1.6 1 1 1 2 2 2 1 MFS/sugar transport protein Frag1 PF10277.9 ORY04797.1 - 0.01 15.4 0.8 0.034 13.7 0.3 2.1 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family UCR_Fe-S_N PF10399.9 ORY04797.1 - 0.021 14.1 0.1 0.021 14.1 0.1 2.9 4 0 0 4 4 4 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF1129 PF06570.11 ORY04797.1 - 0.12 11.8 7.9 0.053 13.0 5.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 ORY04797.1 - 0.2 11.3 4.2 8.2 6.0 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SYS1 PF09801.9 ORY04797.1 - 0.3 11.2 3.6 1.5 8.9 0.7 2.2 1 1 1 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Sugar_tr PF00083.24 ORY04798.1 - 4.8e-45 154.2 17.3 1.1e-37 130.0 6.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY04798.1 - 6.1e-35 120.8 25.0 6.1e-35 120.8 25.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY04798.1 - 4.1e-05 22.3 24.3 6.4e-05 21.7 10.3 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein UCR_Fe-S_N PF10399.9 ORY04798.1 - 0.04 13.3 0.1 0.04 13.3 0.1 3.7 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pkinase PF00069.25 ORY04799.1 - 3.7e-60 203.5 0.0 1.4e-59 201.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04799.1 - 9.6e-28 97.2 0.3 5.2e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY04799.1 - 0.00028 20.3 0.1 0.041 13.2 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 ORY04799.1 - 0.0006 20.5 1.3 0.0018 18.9 1.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 ORY04799.1 - 0.001 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY04799.1 - 0.015 14.3 0.3 0.039 12.9 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 ORY04799.1 - 0.027 14.4 0.1 0.58 10.0 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4995 PF16386.5 ORY04799.1 - 0.18 11.8 0.1 0.7 9.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function CBFD_NFYB_HMF PF00808.23 ORY04800.1 - 4.2e-17 62.2 1.1 5.6e-17 61.8 1.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY04800.1 - 8.2e-05 23.0 0.4 8.2e-05 23.0 0.4 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 FoP_duplication PF13865.6 ORY04800.1 - 3.5 8.2 11.4 6.4 7.4 11.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 YCII PF03795.14 ORY04801.1 - 2.3e-14 53.6 0.0 3.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Ribosomal_L30_N PF08079.12 ORY04802.1 - 5.1e-25 87.5 15.9 9.9e-25 86.6 15.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ORY04802.1 - 2.2e-16 59.4 2.1 2.2e-16 59.4 2.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e RRM_1 PF00076.22 ORY04803.1 - 4.9e-38 128.8 0.0 8.3e-19 67.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY04803.1 - 0.00018 21.5 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 ORY04803.1 - 0.001 18.7 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain Cation_efflux PF01545.21 ORY04804.1 - 2.6e-17 63.2 17.0 4.1e-16 59.3 17.0 2.0 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY04804.1 - 1.4e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Myb_DNA-binding PF00249.31 ORY04805.1 - 1.7e-16 60.1 0.1 3.4e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY04805.1 - 1.9e-11 44.0 0.2 1.1e-05 25.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 ORY04805.1 - 0.0019 18.2 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 SLIDE Asp PF00026.23 ORY04806.1 - 5e-110 367.8 0.0 6.6e-110 367.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY04806.1 - 1.7e-15 57.7 0.3 9.6e-13 48.8 0.5 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY04806.1 - 1.4e-06 28.8 0.0 0.0099 16.5 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 ORY04806.1 - 1.4e-05 24.9 0.0 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ORY04806.1 - 0.00023 21.7 0.0 0.46 11.1 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease BBS2_Mid PF14783.6 ORY04807.1 - 3.1e-05 24.0 0.0 0.09 12.8 0.0 3.0 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 ORY04807.1 - 0.037 14.6 2.7 0.23 12.1 0.3 3.0 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAPEG PF01124.18 ORY04808.1 - 3.7e-16 59.2 0.1 4.5e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 MAPEG family GTP_EFTU PF00009.27 ORY04809.1 - 6.5e-54 182.4 0.5 9.8e-54 181.9 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ORY04809.1 - 1e-48 164.0 0.9 2e-48 163.0 0.9 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ORY04809.1 - 1.6e-21 76.1 0.1 3.7e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY04809.1 - 8.8e-07 29.2 1.6 1.4e-06 28.6 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY04809.1 - 5e-06 26.4 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 ORY04809.1 - 1.7e-05 24.4 0.2 7.7e-05 22.2 0.2 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 ORY04809.1 - 1.8e-05 24.7 0.0 4.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY04809.1 - 0.00016 21.7 0.1 0.00035 20.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 ORY04809.1 - 0.00022 20.8 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 Ras family Septin PF00735.18 ORY04809.1 - 0.00087 18.7 2.5 0.12 11.6 0.1 2.6 3 0 0 3 3 3 2 Septin MMR_HSR1_Xtn PF16897.5 ORY04809.1 - 0.077 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 ORY04809.1 - 0.15 12.2 0.5 1.3 9.3 0.0 2.7 2 2 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase CTK3 PF12243.8 ORY04810.1 - 4.5e-35 120.3 0.1 7.7e-35 119.6 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 ORY04810.1 - 1.8e-18 66.4 7.0 3.9e-18 65.4 7.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTD_bind PF04818.13 ORY04810.1 - 3.8e-05 24.4 0.0 8.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. P66_CC PF16563.5 ORY04810.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.3 2 1 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 HORMA PF02301.18 ORY04811.1 - 1.4e-05 24.8 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 HORMA domain HLH PF00010.26 ORY04812.1 - 6.4e-06 26.0 2.0 1.1e-05 25.2 2.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SURF4 PF02077.15 ORY04813.1 - 4.9e-91 305.0 11.4 5.5e-91 304.9 11.4 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 ORY04813.1 - 0.014 16.0 2.3 0.014 16.0 2.3 3.2 2 1 1 3 3 3 0 DoxX ThrE PF06738.12 ORY04813.1 - 9.1 5.6 13.3 0.33 10.3 1.8 2.2 2 0 0 2 2 2 0 Putative threonine/serine exporter NTP_transferase PF00483.23 ORY04814.1 - 5.7e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY04814.1 - 3.1e-09 37.4 0.0 1.6e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep PF00132.24 ORY04814.1 - 6.6e-08 32.0 11.3 0.011 15.4 1.1 3.9 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 ORY04814.1 - 0.0001 20.7 4.3 0.00034 18.9 4.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 ORY04814.1 - 0.084 12.6 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 ORY04814.1 - 0.14 11.9 16.7 5 7.0 0.2 4.2 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Img2 PF05046.14 ORY04815.1 - 2.5e-27 95.0 0.3 3e-27 94.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 ORY04815.1 - 0.0065 17.0 0.0 0.011 16.2 0.0 1.4 1 1 0 1 1 1 1 Translation initiation factor SUI1 UCH PF00443.29 ORY04816.1 - 4.9e-55 186.8 0.0 1.1e-54 185.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY04816.1 - 5.1e-26 92.0 9.8 8.8e-21 74.8 3.8 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ORY04816.1 - 0.00026 20.6 4.3 0.14 11.6 3.6 3.4 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Pkinase PF00069.25 ORY04817.1 - 8.8e-73 244.9 0.0 1.1e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04817.1 - 5.2e-36 124.2 0.0 7e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY04817.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY04817.1 - 0.18 11.7 0.1 0.68 9.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sin3a_C PF16879.5 ORY04818.1 - 1.6e-71 241.4 1.6 2.3e-70 237.6 1.9 2.8 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY04818.1 - 5.3e-45 151.3 16.9 5.5e-17 61.6 0.0 4.8 4 1 1 5 5 5 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY04818.1 - 1.4e-41 140.5 0.2 1.4e-41 140.5 0.2 2.4 2 0 0 2 2 2 1 Sin3 family co-repressor ArfGap PF01412.18 ORY04819.1 - 1.9e-30 105.3 0.1 2.1e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 ORY04819.1 - 0.046 13.7 0.7 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger UBA PF00627.31 ORY04820.1 - 3.7e-17 61.9 1.6 1.1e-08 34.8 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain CUE PF02845.16 ORY04820.1 - 0.0015 18.2 1.0 0.62 9.8 0.0 2.9 3 0 0 3 3 3 2 CUE domain HOIP-UBA PF16678.5 ORY04820.1 - 0.0024 17.9 1.2 0.038 14.0 1.2 2.2 1 1 0 1 1 1 1 HOIP UBA domain pair Calreticulin PF00262.18 ORY04821.1 - 2.5e-169 562.9 19.6 3.3e-169 562.5 19.6 1.2 1 0 0 1 1 1 1 Calreticulin family FMN_red PF03358.15 ORY04822.1 - 3.6e-09 36.5 0.0 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY04822.1 - 0.0058 16.4 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ORY04823.1 - 3.9e-09 36.4 0.0 5.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY04823.1 - 0.008 15.9 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ORY04824.1 - 5.7e-09 35.9 0.0 8.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY04824.1 - 0.0065 16.2 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ORY04825.1 - 5.7e-09 35.9 0.0 8.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY04825.1 - 0.0065 16.2 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Sedlin_N PF04628.13 ORY04826.1 - 1.9e-45 154.2 0.2 2.1e-45 154.1 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORY04826.1 - 8.9e-06 25.7 0.1 1.4e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Sybindin-like family zf-C2H2_4 PF13894.6 ORY04827.1 - 1.8e-05 25.2 3.1 0.0079 17.0 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY04827.1 - 2.8e-05 24.3 2.8 0.0068 16.7 0.8 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 ORY04827.1 - 0.00022 21.5 2.5 0.075 13.5 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY04827.1 - 0.00055 20.2 1.7 0.56 10.6 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Ima1_N PF09779.9 ORY04827.1 - 0.0017 19.2 0.1 0.0031 18.4 0.1 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain Actin_micro PF17003.5 ORY04827.1 - 0.36 10.0 1.5 11 5.0 0.4 2.0 2 0 0 2 2 2 0 Putative actin-like family Rad50_zn_hook PF04423.14 ORY04827.1 - 0.51 10.2 2.8 14 5.6 0.3 2.3 1 1 1 2 2 2 0 Rad50 zinc hook motif PyrI_C PF02748.15 ORY04827.1 - 2 8.4 3.8 6.2 6.8 0.2 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Sld5 PF05916.11 ORY04828.1 - 5.4e-08 33.3 0.1 7.8e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Pyr_redox_2 PF07992.14 ORY04829.1 - 1.7e-50 171.9 0.0 2.2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY04829.1 - 5.6e-11 42.8 0.0 2.1e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY04829.1 - 0.00023 20.5 0.0 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4342 PF14242.6 ORY04829.1 - 0.048 13.7 0.2 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DAO PF01266.24 ORY04829.1 - 0.06 12.9 0.1 3.9 7.0 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY04829.1 - 0.31 9.7 1.4 3 6.4 0.0 2.3 1 1 0 2 2 2 0 HI0933-like protein B12D PF06522.11 ORY04830.1 - 0.014 15.2 1.2 0.029 14.2 1.2 1.6 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit tRNA_m1G_MT PF01746.21 ORY04830.1 - 0.057 13.1 0.1 0.07 12.8 0.1 1.1 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase GPI-anchored PF10342.9 ORY04831.1 - 2.4e-16 60.3 0.1 4.6e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 ORY04832.1 - 7.1e-79 264.9 0.0 8e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY04832.1 - 1.4e-35 122.8 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY04832.1 - 6.4e-05 22.1 0.2 0.00041 19.4 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY04832.1 - 0.0037 16.6 0.1 0.13 11.6 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORY04832.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY04832.1 - 0.071 12.4 0.3 0.15 11.4 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L22 PF00237.19 ORY04833.1 - 6.2e-43 145.2 0.1 8.4e-43 144.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e YEATS PF03366.16 ORY04834.1 - 6e-22 77.4 0.1 1.1e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 YEATS family Dynamin_N PF00350.23 ORY04835.1 - 4.4e-14 52.9 0.0 4.4e-14 52.9 0.0 3.2 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORY04835.1 - 2e-10 40.8 0.0 1.6e-09 37.9 0.0 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY04835.1 - 4.3e-08 32.9 0.2 2.8e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 ORY04835.1 - 0.0062 16.1 0.0 4.7 6.7 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 ORY04835.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORY04835.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 ORY04835.1 - 0.026 14.9 0.2 0.15 12.5 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain Roc PF08477.13 ORY04835.1 - 0.059 13.6 0.3 0.7 10.1 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ORY04835.1 - 0.088 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY04835.1 - 0.2 11.5 3.2 2.8 7.8 0.0 3.3 3 1 1 4 4 4 0 RsgA GTPase DUF4735 PF15882.5 ORY04835.1 - 5.4 6.4 7.0 1 8.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4735) FliD_N PF02465.18 ORY04835.1 - 5.7 7.7 7.0 36 5.1 1.9 3.3 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus tRNA-synt_His PF13393.6 ORY04836.1 - 9.4e-39 133.5 0.1 6.6e-38 130.7 0.1 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ORY04836.1 - 2.3e-16 59.7 0.2 5.1e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 ORY04836.1 - 2.9e-14 53.0 5.7 7.2e-14 51.7 5.3 2.0 1 1 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 ORY04836.1 - 6.4e-09 35.7 1.1 8.4e-09 35.3 0.1 1.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 ORY04836.1 - 1.5e-05 25.1 0.0 4.1e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ORY04836.1 - 0.0008 18.6 0.2 0.009 15.1 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Isy1 PF06246.12 ORY04837.1 - 3.7e-96 321.6 8.6 4.3e-96 321.4 8.6 1.0 1 0 0 1 1 1 1 Isy1-like splicing family GLE1 PF07817.13 ORY04837.1 - 0.074 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein MRP-L47 PF06984.13 ORY04838.1 - 8.3e-27 93.2 1.1 1.3e-26 92.5 1.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 ORY04838.1 - 1.2e-06 28.4 0.9 2.1e-06 27.6 0.9 1.5 1 1 0 1 1 1 1 Ribosomal L29 protein Homeobox_KN PF05920.11 ORY04839.1 - 2.8e-19 68.7 0.4 5e-19 67.9 0.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY04839.1 - 4.8e-08 32.7 0.1 9.5e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Clat_adaptor_s PF01217.20 ORY04840.1 - 1.8e-51 173.8 1.3 2.1e-51 173.6 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 ORY04841.1 - 2e-15 56.4 0.0 3.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPS2_interact PF15784.5 ORY04841.1 - 0.0054 17.1 4.0 0.0088 16.5 4.0 1.3 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain FTA4 PF13093.6 ORY04841.1 - 0.016 15.1 0.7 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Tektin PF03148.14 ORY04841.1 - 0.018 13.8 3.8 0.023 13.5 3.8 1.1 1 0 0 1 1 1 0 Tektin family SKA1 PF07160.12 ORY04841.1 - 0.022 14.6 1.1 0.03 14.2 1.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3251 PF11622.8 ORY04841.1 - 0.025 14.2 0.5 0.038 13.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) APG6_N PF17675.1 ORY04841.1 - 0.063 13.8 5.6 0.087 13.4 5.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3987 PF13148.6 ORY04841.1 - 0.087 11.8 0.4 0.11 11.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YabA PF06156.13 ORY04841.1 - 0.092 13.4 1.5 0.14 12.8 1.5 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Nup35_RRM_2 PF14605.6 ORY04841.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Lge1 PF11488.8 ORY04841.1 - 0.23 11.6 3.3 19 5.5 4.9 2.2 1 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 V_ATPase_I PF01496.19 ORY04841.1 - 0.35 8.7 1.9 0.36 8.7 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 ORY04841.1 - 0.38 11.0 4.0 0.64 10.3 4.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 ORY04841.1 - 0.42 10.4 4.1 0.7 9.7 4.1 1.3 1 0 0 1 1 1 0 Septum formation initiator XhlA PF10779.9 ORY04841.1 - 0.66 10.2 2.7 1.1 9.5 2.7 1.4 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_2 PF07716.15 ORY04841.1 - 3.2 7.9 9.0 4.8 7.3 9.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper UreF PF01730.16 ORY04842.1 - 1.1e-29 103.6 0.0 1.5e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 UreF ABC_membrane_2 PF06472.15 ORY04843.1 - 2.3e-58 197.8 4.9 3.2e-58 197.3 4.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY04843.1 - 3e-19 69.9 0.0 7.9e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 ORY04843.1 - 0.00025 21.6 1.3 0.00087 19.9 0.1 2.4 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 ORY04843.1 - 0.0014 18.1 0.3 0.23 10.9 0.0 3.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY04843.1 - 0.0018 18.7 0.0 0.0045 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORY04843.1 - 0.0036 17.2 0.1 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 ORY04843.1 - 0.0064 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 ORY04843.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY04843.1 - 0.016 15.5 0.1 0.13 12.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY04843.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ORY04843.1 - 0.062 13.7 0.1 0.19 12.2 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DHOR PF06537.11 ORY04843.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase AAA_30 PF13604.6 ORY04843.1 - 0.19 11.4 0.0 3.5 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 ORY04843.1 - 0.52 9.9 9.1 7.3 6.1 9.1 2.5 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_15 PF13175.6 ORY04843.1 - 0.76 9.4 0.0 0.76 9.4 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain Ribosomal_L14 PF00238.19 ORY04844.1 - 3.3e-35 120.8 0.1 4e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e 2-oxoacid_dh PF00198.23 ORY04845.1 - 5.9e-71 238.6 0.2 1.4e-70 237.4 0.2 1.6 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY04845.1 - 3.4e-21 74.9 0.3 8.6e-21 73.6 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY04845.1 - 2.9e-11 43.5 0.1 9.2e-11 41.9 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORY04845.1 - 0.0026 17.5 0.0 0.0092 15.8 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like Pol_alpha_B_N PF08418.10 ORY04845.1 - 0.14 12.1 2.7 0.18 11.7 0.3 2.3 2 1 1 3 3 3 0 DNA polymerase alpha subunit B N-terminal DUF3614 PF12267.8 ORY04845.1 - 0.18 12.3 0.1 0.18 12.3 0.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3614) HOOK PF05622.12 ORY04846.1 - 3.4e-13 48.7 41.2 3.6e-11 42.0 25.1 2.0 1 1 0 2 2 2 2 HOOK protein Pyr_redox_2 PF07992.14 ORY04847.1 - 7.4e-08 32.0 0.0 6.6e-07 28.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY04847.1 - 0.071 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY04847.1 - 0.083 12.9 0.0 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding G-patch_2 PF12656.7 ORY04848.1 - 6.4e-25 87.0 0.4 3.4e-24 84.7 0.1 2.4 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 ORY04848.1 - 9.5e-05 22.2 0.5 0.00023 21.0 0.5 1.6 1 0 0 1 1 1 1 G-patch domain Glyco_hydro_35 PF01301.19 ORY04848.1 - 0.14 11.8 0.4 0.19 11.3 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 VPS9 PF02204.18 ORY04849.1 - 1.4e-31 108.8 0.1 5e-31 107.0 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ORY04849.1 - 2.7e-11 43.6 0.1 1.3e-10 41.4 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 ORY04849.1 - 3.9e-05 23.2 5.1 5.9e-05 22.7 0.1 2.6 3 0 0 3 3 3 1 CUE domain FliS PF02561.14 ORY04849.1 - 0.052 13.8 1.1 0.48 10.7 0.0 2.8 3 0 0 3 3 3 0 Flagellar protein FliS RIX1 PF08167.12 ORY04850.1 - 1.8e-42 145.2 2.9 1.8e-42 145.2 2.9 2.6 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis CSF-1 PF05337.11 ORY04850.1 - 0.077 13.1 0.2 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) 2-Hacid_dh_C PF02826.19 ORY04851.1 - 5.3e-54 182.3 0.0 7.9e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY04851.1 - 5e-19 68.3 0.0 5.5e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY04851.1 - 7.2e-05 23.0 0.0 0.00017 21.8 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY04851.1 - 0.011 16.2 0.0 0.035 14.7 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ORY04851.1 - 0.12 11.9 0.0 0.92 9.1 0.0 2.2 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Nop25 PF09805.9 ORY04852.1 - 7.8e-24 84.7 18.2 7.8e-24 84.7 18.2 2.0 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) NOA36 PF06524.12 ORY04852.1 - 1.4 8.2 7.3 2.3 7.5 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein UbiA PF01040.18 ORY04853.1 - 1.9e-51 174.8 10.4 2.7e-51 174.3 10.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family CTP_transf_like PF01467.26 ORY04854.1 - 3.7e-29 101.8 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DnaJ PF00226.31 ORY04855.1 - 2.7e-21 75.5 0.1 5.9e-20 71.2 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain DUF4917 PF16263.5 ORY04855.1 - 0.0011 18.4 0.2 0.078 12.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4917) DAP PF15228.6 ORY04856.1 - 0.0017 19.5 10.8 0.0025 18.9 10.8 1.3 1 1 0 1 1 1 1 Death-associated protein NAC PF01849.18 ORY04857.1 - 1.6e-21 76.0 2.2 2e-21 75.7 0.0 2.2 3 0 0 3 3 3 1 NAC domain Ribosomal_L37 PF08561.10 ORY04857.1 - 1.9 9.1 6.9 0.76 10.3 2.7 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Spore_coat_CotO PF14153.6 ORY04857.1 - 5.6 6.9 9.8 1.3 8.9 3.6 2.0 2 0 0 2 2 2 0 Spore coat protein CotO FMN_red PF03358.15 ORY04858.1 - 4.2e-06 26.6 0.0 6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY04858.1 - 0.01 15.5 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Flavodoxin-like fold FMN_red PF03358.15 ORY04859.1 - 3.7e-09 36.5 0.0 5.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY04859.1 - 0.0064 16.2 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold RMI2 PF16100.5 ORY04893.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 RecQ-mediated genome instability protein 2 FYRC PF05965.14 ORY04894.1 - 3.3e-22 78.4 0.0 8.7e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 ORY04894.1 - 6.8e-20 70.6 0.1 1.3e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF16 PF01519.16 ORY04894.1 - 0.0015 19.0 0.3 0.0028 18.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 PspA_IM30 PF04012.12 ORY04894.1 - 0.01 15.4 0.7 0.019 14.6 0.7 1.3 1 0 0 1 1 1 0 PspA/IM30 family Med9 PF07544.13 ORY04894.1 - 0.017 15.2 2.1 0.058 13.5 2.1 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPD52 PF04201.15 ORY04894.1 - 0.017 14.7 1.8 0.031 13.9 1.8 1.4 1 0 0 1 1 1 0 Tumour protein D52 family UPF0242 PF06785.11 ORY04894.1 - 0.019 15.1 5.6 0.027 14.6 5.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 ORY04894.1 - 0.022 15.4 0.2 0.049 14.3 0.2 1.6 1 0 0 1 1 1 0 SlyX Ino80_Iec3 PF14612.6 ORY04894.1 - 0.041 14.5 6.3 0.072 13.7 6.3 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Herpes_BBRF1 PF04793.12 ORY04894.1 - 0.055 12.5 0.4 2.7 7.0 0.1 2.1 2 0 0 2 2 2 0 BRRF1-like protein YkyA PF10368.9 ORY04894.1 - 0.063 12.9 3.0 0.089 12.5 3.0 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein PhoU PF01895.19 ORY04894.1 - 0.07 13.6 0.9 0.12 12.9 0.9 1.3 1 0 0 1 1 1 0 PhoU domain TMEM192 PF14802.6 ORY04894.1 - 0.087 11.9 1.5 0.13 11.3 1.5 1.3 1 0 0 1 1 1 0 TMEM192 family Herpes_UL6 PF01763.16 ORY04894.1 - 0.11 11.0 0.5 0.15 10.5 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like YabA PF06156.13 ORY04894.1 - 0.18 12.5 1.2 0.3 11.7 1.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA CCDC-167 PF15188.6 ORY04894.1 - 0.19 12.1 3.6 0.099 13.0 1.1 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 DUF4515 PF14988.6 ORY04894.1 - 0.22 11.4 6.2 0.14 12.0 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) CCDC106 PF15794.5 ORY04894.1 - 0.34 10.6 7.4 0.52 10.0 7.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TSC22 PF01166.18 ORY04894.1 - 0.48 10.8 3.8 1 9.7 3.8 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Geminin PF07412.12 ORY04894.1 - 1.1 8.9 11.3 0.25 11.1 7.8 1.7 1 1 1 2 2 2 0 Geminin TMPIT PF07851.13 ORY04894.1 - 1.2 8.4 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cep57_MT_bd PF06657.13 ORY04894.1 - 1.8 9.1 6.5 0.48 10.9 2.6 2.2 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 KIAA1430 PF13879.6 ORY04894.1 - 3 8.6 9.3 8.6 7.2 9.3 1.9 1 1 0 1 1 1 0 KIAA1430 homologue CLASP_N PF12348.8 ORY04895.1 - 4.1e-77 258.8 5.7 2.1e-62 210.6 0.0 4.5 4 1 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 ORY04895.1 - 5.2e-13 48.0 3.7 0.016 15.4 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 ORY04895.1 - 6.6e-07 29.5 0.1 0.62 10.1 0.0 4.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY04895.1 - 9.7e-07 29.1 0.1 0.64 10.4 0.0 5.6 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 ORY04895.1 - 5.5e-05 23.6 1.5 0.23 12.0 0.1 4.0 3 0 0 3 3 3 2 HEAT-like repeat Cnd3 PF12719.7 ORY04895.1 - 0.066 12.4 0.9 0.53 9.4 0.2 2.8 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 ORY04895.1 - 0.1 12.5 0.1 32 4.4 0.0 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Aminotran_3 PF00202.21 ORY04895.1 - 0.17 10.5 0.0 0.33 9.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Amidohydro_1 PF01979.20 ORY04896.1 - 6.9e-20 71.6 0.1 1.3e-19 70.8 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY04896.1 - 8.2e-06 25.5 0.2 4.2e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family NAD_binding_3 PF03447.16 ORY04896.1 - 0.046 14.4 0.0 0.093 13.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glucosamine_iso PF01182.20 ORY04897.1 - 1.9e-20 73.8 0.0 2.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NADH_B2 PF14813.6 ORY04898.1 - 0.0006 19.6 0.1 0.00076 19.2 0.0 1.2 1 1 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 YjeF_N PF03853.15 ORY04899.1 - 1.5e-32 112.8 0.0 2.7e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Luteo_Vpg PF01659.16 ORY04899.1 - 0.2 12.0 5.2 0.49 10.8 5.2 1.6 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein RNase_T PF00929.24 ORY04900.1 - 2.4e-14 54.2 0.0 2.7e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Tyrosinase PF00264.20 ORY04901.1 - 5.6e-38 131.5 5.0 4.1e-37 128.6 5.0 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase PQ-loop PF04193.14 ORY04902.1 - 1.3e-18 66.5 18.1 2.8e-11 43.0 0.7 3.6 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 ORY04902.1 - 3 7.9 13.0 10 6.3 0.1 3.5 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4149 PF13664.6 ORY04902.1 - 3.1 8.2 14.6 4.7 7.6 2.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4149) CPBP PF02517.16 ORY04903.1 - 4.2e-12 46.3 6.7 4.2e-12 46.3 6.7 2.9 2 1 0 3 3 3 1 CPBP intramembrane metalloprotease Fungal_trans PF04082.18 ORY04904.1 - 1.7e-42 145.3 1.5 1.7e-42 145.3 1.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY04904.1 - 9.9e-12 44.8 10.2 1.7e-11 44.0 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY04904.1 - 9.2e-06 24.7 4.4 1.4e-05 24.1 4.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mitoc_mL59 PF18126.1 ORY04905.1 - 5.5e-14 52.6 2.6 4.3e-13 49.7 2.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 SH3_1 PF00018.28 ORY04906.1 - 1.2e-25 88.8 0.0 4.3e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY04906.1 - 6e-20 70.8 0.0 2e-09 37.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORY04906.1 - 1.4e-19 69.5 0.0 2.2e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 ORY04906.1 - 6.5e-15 55.1 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 ORY04906.1 - 8.8e-09 35.2 0.1 4e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 PB1 domain ArfGap PF01412.18 ORY04907.1 - 2.7e-39 133.9 0.2 5.2e-39 132.9 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 ORY04907.1 - 1.7e-21 76.6 4.2 1.1e-11 45.2 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY04907.1 - 1.3e-13 51.2 0.9 1.3e-06 28.8 0.1 3.7 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY04907.1 - 1.6e-08 34.6 0.2 3.8e-07 30.3 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY04907.1 - 2.1e-08 33.7 0.7 0.00053 20.2 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 ORY04907.1 - 0.00018 21.8 3.8 0.0091 16.4 0.0 4.1 4 1 1 5 5 5 1 Ankyrin repeat Ribosomal_S7e PF01251.18 ORY04908.1 - 1.8e-86 288.6 2.5 2e-86 288.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.22 ORY04909.1 - 6.4e-59 198.2 0.2 8.2e-59 197.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY04909.1 - 1.4e-36 125.3 0.0 2.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY04909.1 - 6.1e-18 64.9 0.1 8.7e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY04909.1 - 1.2e-07 31.4 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY04909.1 - 2.4e-07 30.5 0.3 4e-07 29.8 0.2 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY04909.1 - 3.1e-06 27.2 0.0 6.7e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY04909.1 - 0.00077 19.9 0.1 0.0015 19.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY04909.1 - 0.0032 17.4 2.1 1.9 8.4 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase D5_N PF08706.11 ORY04909.1 - 0.039 14.2 0.1 0.1 12.9 0.0 1.6 1 1 0 2 2 2 0 D5 N terminal like ATPase_2 PF01637.18 ORY04909.1 - 0.12 12.2 1.1 8.3 6.2 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 ORY04909.1 - 0.13 11.4 0.1 0.22 10.6 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit RhoGAP PF00620.27 ORY04910.1 - 6.4e-48 162.4 0.0 8.3e-47 158.8 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.19 ORY04910.1 - 6.8e-19 68.7 0.0 1.2e-15 58.1 0.0 3.5 2 1 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 ORY04910.1 - 2.2e-13 50.4 0.2 2.6e-12 46.9 0.1 3.0 2 0 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.29 ORY04910.1 - 8.1e-07 29.5 0.0 2.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 ORY04910.1 - 9.5e-07 29.2 0.9 1.1e-05 25.8 1.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain WD40 PF00400.32 ORY04911.1 - 4e-23 81.3 0.7 9.9e-06 26.2 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY04911.1 - 8.5e-13 48.4 0.1 0.019 15.3 0.0 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY04911.1 - 1.1e-05 24.9 0.1 0.0002 20.8 0.5 2.2 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 ORY04911.1 - 0.00035 19.6 0.0 4.9 6.0 0.0 3.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CitMHS PF03600.16 ORY04912.1 - 2.3e-22 79.6 57.3 3.2e-18 65.9 34.5 2.4 1 1 2 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.19 ORY04912.1 - 1.2e-19 70.7 38.4 1.8e-19 70.2 38.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Aldedh PF00171.22 ORY04913.1 - 1.5e-168 561.1 0.0 1.7e-168 560.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FUSC-like PF12805.7 ORY04913.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS XPG_N PF00752.17 ORY04915.1 - 3.6e-35 120.5 0.0 8.2e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY04915.1 - 2.1e-27 95.3 0.1 6.9e-27 93.6 0.1 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 ORY04915.1 - 0.023 15.3 0.1 0.95 10.1 0.0 3.4 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold PRANC PF09372.10 ORY04915.1 - 0.18 12.1 0.6 12 6.3 0.0 3.2 3 0 0 3 3 3 0 PRANC domain UBM PF14377.6 ORY04915.1 - 0.22 11.0 2.5 0.24 10.9 0.5 2.1 2 0 0 2 2 2 0 Ubiquitin binding region Glycos_transf_4 PF00953.21 ORY04917.1 - 2.1e-34 118.8 13.5 2.1e-34 118.8 13.5 1.8 3 0 0 3 3 3 1 Glycosyl transferase family 4 Myb_DNA-bind_4 PF13837.6 ORY04918.1 - 4.2e-07 30.3 1.1 9.3e-07 29.1 0.4 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY04918.1 - 0.0021 18.3 0.8 0.16 12.3 0.5 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 ORY04918.1 - 0.029 14.6 1.1 0.39 11.0 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain YabA PF06156.13 ORY04918.1 - 0.11 13.2 0.2 0.25 12.0 0.2 1.6 1 0 0 1 1 1 0 Initiation control protein YabA SlyX PF04102.12 ORY04919.1 - 3.1 8.5 8.4 4.8 7.9 7.3 1.9 1 1 1 2 2 2 0 SlyX DUF4097 PF13349.6 ORY04920.1 - 0.00034 20.1 0.2 0.00056 19.3 0.2 1.3 1 1 0 1 1 1 1 Putative adhesin HLH PF00010.26 ORY04921.1 - 4.2e-11 42.6 0.4 4.2e-11 42.6 0.4 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RcbX PF02341.15 ORY04921.1 - 0.071 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 RbcX protein DUF4436 PF14494.6 ORY04922.1 - 4.3e-29 101.6 0.4 5.6e-29 101.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4131 PF13567.6 ORY04922.1 - 0.45 10.1 2.0 4.3 6.9 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 ORY04922.1 - 0.79 8.4 3.1 2.1 7.0 0.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3169 PF11368.8 ORY04922.1 - 7 6.1 7.0 13 5.2 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4436 PF14494.6 ORY04923.1 - 3.1e-14 52.9 7.0 3.5e-14 52.7 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) bZIP_1 PF00170.21 ORY04924.1 - 9.3e-14 51.3 12.8 9.3e-14 51.3 12.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY04924.1 - 8.1e-13 48.2 15.2 1.3e-12 47.6 15.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY04924.1 - 9e-09 35.7 2.6 1.5e-08 35.0 2.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 ORY04924.1 - 0.023 15.1 1.6 0.048 14.1 1.6 1.6 1 0 0 1 1 1 0 Nnf1 Fungal_TACC PF12709.7 ORY04924.1 - 0.038 14.4 0.7 0.065 13.7 0.7 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 ORY04924.1 - 0.11 12.8 1.2 0.37 11.1 1.1 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 ORY04924.1 - 0.2 11.4 4.0 0.32 10.8 4.0 1.2 1 0 0 1 1 1 0 Septum formation initiator AA_permease PF00324.21 ORY04925.1 - 1.4e-134 449.4 34.1 1.7e-134 449.1 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY04925.1 - 1.9e-38 132.4 37.4 2.3e-38 132.1 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 ORY04925.1 - 0.0086 16.8 0.1 0.0086 16.8 0.1 4.8 4 1 0 4 4 4 1 PrgI family protein Lipase_3 PF01764.25 ORY04926.1 - 8.7e-16 58.1 0.0 2.4e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORY04926.1 - 0.024 13.9 0.1 0.055 12.7 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY04926.1 - 0.075 13.6 0.3 0.075 13.6 0.3 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family BTB_3 PF16017.5 ORY04926.1 - 0.13 12.4 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Ribosomal_S24e PF01282.19 ORY04927.1 - 1.3e-38 130.8 1.6 1.3e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e Rhodanese PF00581.20 ORY04928.1 - 1.6e-13 51.1 0.0 2.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PPTA PF01239.22 ORY04929.1 - 3.1e-22 77.6 23.5 1.2e-06 28.0 0.4 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DNA_pol_A_exo1 PF01612.20 ORY04931.1 - 3.8e-20 72.3 0.0 8.6e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease NDUF_C2 PF06374.11 ORY04932.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) SNARE_assoc PF09335.11 ORY04933.1 - 4.2e-17 62.7 4.7 4.2e-17 62.7 4.7 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein Clathrin PF00637.20 ORY04934.1 - 1.5e-29 102.7 1.9 1.5e-29 102.7 1.9 4.1 4 2 0 4 4 4 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 ORY04934.1 - 0.0033 17.7 0.0 0.53 10.6 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY04934.1 - 0.013 16.3 0.2 0.063 14.2 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat TPR_7 PF13176.6 ORY04934.1 - 0.027 14.5 4.1 2.5 8.3 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY04934.1 - 0.028 15.2 0.9 3.6 8.7 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY04934.1 - 0.035 14.6 1.8 11 6.6 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.9 ORY04934.1 - 0.048 14.1 0.1 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 TPR_8 PF13181.6 ORY04934.1 - 0.77 10.1 5.8 17 6.0 0.5 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY04934.1 - 1.3 8.9 7.8 1.6 8.7 0.7 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY04934.1 - 2.2 8.6 9.4 1 9.6 0.1 3.9 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 ORY04934.1 - 2.6 8.4 6.9 52 4.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 ORY04935.1 - 1.3e-44 150.1 10.5 3.6e-15 55.9 1.4 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY04935.1 - 9.1e-37 125.1 0.3 3.3e-14 52.9 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY04935.1 - 0.0002 21.4 1.2 1.5 9.0 1.2 3.5 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain HAUS-augmin3 PF14932.6 ORY04935.1 - 0.00037 20.1 3.3 0.00052 19.7 3.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Myb_DNA-bind_4 PF13837.6 ORY04935.1 - 0.00093 19.5 3.1 7.6 7.0 0.0 4.3 4 0 0 4 4 4 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 ORY04935.1 - 0.0045 17.0 0.0 1.2 9.2 0.0 3.3 1 1 2 3 3 3 1 SLIDE PKcGMP_CC PF16808.5 ORY04935.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase APG6_N PF17675.1 ORY04935.1 - 0.15 12.6 7.0 0.26 11.8 7.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region KxDL PF10241.9 ORY04935.1 - 1.5 9.1 6.4 1.8 8.9 1.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein Carn_acyltransf PF00755.20 ORY04936.1 - 2.1e-205 683.8 0.0 2.5e-205 683.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1678 PF07913.11 ORY04936.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) SET PF00856.28 ORY04937.1 - 2.4e-07 31.3 0.0 4.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY04937.1 - 0.00035 20.6 9.7 0.00035 20.6 9.7 3.0 3 1 0 3 3 3 1 MYND finger MutS_III PF05192.18 ORY04938.1 - 2.8e-27 96.2 1.3 5.7e-27 95.2 1.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 ORY04938.1 - 6.3e-17 62.2 0.2 1.2e-16 61.3 0.2 1.5 1 0 0 1 1 1 1 MutS domain V Mito_carr PF00153.27 ORY04939.1 - 1e-54 182.4 2.4 7.7e-20 70.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2953 PF11167.8 ORY04939.1 - 0.037 14.1 0.1 0.088 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Peptidase_U4 PF03419.13 ORY04939.1 - 0.13 11.5 0.1 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Serine_protease PF18405.1 ORY04939.1 - 0.33 10.1 7.2 4.2 6.4 0.4 3.6 3 1 1 4 4 4 0 Gammaproteobacterial serine protease RHD3 PF05879.12 ORY04980.1 - 1.4e-14 53.3 10.3 1.4e-14 53.3 10.3 2.7 2 1 0 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 ORY04980.1 - 3e-05 23.4 0.9 0.00027 20.3 0.1 2.5 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 ORY04980.1 - 0.0014 18.6 0.0 0.004 17.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY04980.1 - 0.0023 18.0 0.1 0.033 14.3 0.0 2.7 1 1 1 2 2 2 1 Dynamin family NTase_sub_bind PF08780.11 ORY04980.1 - 0.12 12.3 8.6 1.4 8.9 0.1 3.3 3 1 1 4 4 4 0 Nucleotidyltransferase substrate binding protein like DUF445 PF04286.12 ORY04980.1 - 0.2 11.4 9.0 1.2 8.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF445) DUSP PF06337.12 ORY04980.1 - 2.7 8.7 6.9 1.5 9.5 1.7 3.0 3 0 0 3 3 3 0 DUSP domain Cu-oxidase_2 PF07731.14 ORY04981.1 - 1.2e-46 157.9 8.9 5.7e-42 142.7 0.9 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY04981.1 - 9.5e-37 125.6 4.6 7.4e-36 122.8 0.3 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY04981.1 - 5.6e-35 120.8 3.5 6.3e-34 117.4 0.5 2.8 3 0 0 3 3 3 1 Multicopper oxidase Peptidase_M30 PF10460.9 ORY04981.1 - 0.015 14.2 0.0 0.031 13.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase M30 Cupredoxin_1 PF13473.6 ORY04981.1 - 0.046 13.8 0.0 7 6.8 0.0 3.1 2 2 0 2 2 2 0 Cupredoxin-like domain Glyco_hydro_18 PF00704.28 ORY04982.1 - 6.3e-25 88.6 2.0 2.1e-24 86.9 2.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORY04982.1 - 0.00018 21.9 24.4 0.00059 20.3 10.0 5.2 6 0 0 6 6 6 2 Carbohydrate binding domain Mucin PF01456.17 ORY04982.1 - 3.8 7.5 22.8 8.8 6.3 22.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SNF2_N PF00176.23 ORY04983.1 - 1.2e-84 284.0 0.0 1.8e-84 283.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY04983.1 - 1.1e-16 61.2 0.0 2.5e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORY04983.1 - 2.3e-10 40.2 6.1 3.7e-10 39.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY04983.1 - 6.2e-08 32.4 7.6 1.2e-07 31.5 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY04983.1 - 1.2e-07 31.4 8.0 3.5e-07 29.9 8.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY04983.1 - 3.4e-07 30.5 7.1 6.5e-07 29.6 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 ORY04983.1 - 1.1e-06 28.8 0.0 4.2e-06 26.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HIRAN PF08797.11 ORY04983.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.29 ORY04983.1 - 1.6e-06 28.0 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 ORY04983.1 - 2.2e-06 27.4 4.3 6e-06 26.0 4.4 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY04983.1 - 6e-06 26.2 4.0 8.9e-06 25.6 2.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY04983.1 - 7.9e-06 25.9 10.0 1.6e-05 25.0 10.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY04983.1 - 5.3e-05 23.1 5.6 0.00011 22.1 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY04983.1 - 0.045 13.8 1.0 0.1 12.7 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY04983.1 - 0.14 12.4 3.8 0.33 11.3 3.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY04983.1 - 0.69 9.8 3.5 2.1 8.3 3.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 ORY04983.1 - 1.6 8.6 5.3 4.8 7.1 5.3 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 ORY04983.1 - 2.6 7.9 6.9 6.5 6.6 6.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 ORY04983.1 - 3.6 7.5 5.5 0.52 10.2 0.5 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif GATA PF00320.27 ORY04984.1 - 3.2e-13 49.0 7.0 5.8e-13 48.2 7.0 1.4 1 0 0 1 1 1 1 GATA zinc finger RecO_C PF02565.15 ORY04984.1 - 0.026 14.3 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Recombination protein O C terminal GCV_H PF01597.19 ORY04985.1 - 2e-44 150.4 0.1 2.4e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein FTR_C PF02741.15 ORY04985.1 - 0.061 13.4 0.1 0.09 12.8 0.1 1.3 1 1 0 1 1 1 0 FTR, proximal lobe DUF572 PF04502.13 ORY04986.1 - 1.9e-69 234.9 0.3 2.2e-69 234.7 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) ZZ PF00569.17 ORY04986.1 - 0.14 12.0 0.7 3.3 7.6 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type GPI-anchored PF10342.9 ORY04987.1 - 0.0039 17.9 0.1 0.0056 17.4 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Arrestin_C PF02752.22 ORY04987.1 - 0.025 15.0 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF1573 PF07610.11 ORY04987.1 - 0.12 12.4 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) PH PF00169.29 ORY04988.1 - 1.9e-32 111.9 10.2 4.8e-16 59.2 0.9 2.3 2 0 0 2 2 2 2 PH domain PH_3 PF14593.6 ORY04988.1 - 1.3e-13 50.9 7.5 5e-07 29.8 1.3 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 ORY04988.1 - 1.1e-12 48.3 18.9 1.6e-06 28.5 5.8 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 ORY04988.1 - 4.9e-09 36.6 10.7 0.00044 20.6 2.2 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 ORY04988.1 - 6.4e-08 32.8 8.1 0.0017 18.6 0.3 2.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 ORY04988.1 - 0.0054 17.1 0.5 0.43 11.0 0.0 2.5 2 0 0 2 2 2 1 Plant pleckstrin homology-like region DUF5530 PF17670.1 ORY04988.1 - 0.0058 16.4 0.9 0.15 11.9 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5530) BHD_1 PF10403.9 ORY04988.1 - 0.097 12.5 0.2 5.8 6.8 0.2 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 PH_13 PF16652.5 ORY04988.1 - 0.35 10.6 3.8 7 6.4 0.3 2.8 3 1 0 3 3 3 0 Pleckstrin homology domain BCL_N PF04714.13 ORY04988.1 - 0.98 9.5 7.8 2.1 8.5 1.2 2.7 2 1 0 2 2 2 0 BCL7, N-terminal conserver region PAP_assoc PF03828.19 ORY04989.1 - 5.4e-17 61.7 0.9 1.2e-16 60.7 0.9 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY04989.1 - 5.6e-10 39.4 0.0 9.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY04989.1 - 6.3e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Serpin PF00079.20 ORY04990.1 - 1.4e-77 261.5 0.0 1.7e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Phage_holin_2_4 PF16082.5 ORY04991.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Acyl-CoA_dh_1 PF00441.24 ORY04992.1 - 2.6e-26 92.6 4.2 9.1e-25 87.6 0.0 2.5 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 ORY04992.1 - 1.4e-22 80.3 0.0 3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY04992.1 - 5.6e-12 45.7 0.0 9.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY04992.1 - 6.1e-06 26.5 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_dehyd_C PF12186.8 ORY04992.1 - 0.0086 16.2 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase C terminal Rhomboid PF01694.22 ORY04993.1 - 6.6e-05 23.0 6.4 6.6e-05 23.0 6.4 1.9 2 0 0 2 2 2 1 Rhomboid family Roughex PF06020.11 ORY04993.1 - 0.24 10.5 0.7 0.39 9.8 0.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein PLA2G12 PF06951.11 ORY04994.1 - 3.6e-12 46.5 14.2 4.6e-12 46.2 14.2 1.1 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 ORY04994.1 - 1.2e-08 35.5 5.0 2.5e-08 34.5 5.0 1.5 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF1353 PF07087.11 ORY04994.1 - 0.034 13.9 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1353) Tyrosinase PF00264.20 ORY04995.1 - 4.4e-21 76.2 0.7 8.2e-20 72.0 0.7 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase LPMO_10 PF03067.15 ORY04996.1 - 3.3e-05 24.6 0.3 0.00015 22.5 0.3 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY04996.1 - 0.035 14.0 0.1 1.3 8.9 0.1 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Slu7 PF11708.8 ORY04997.1 - 3.7e-111 371.2 16.2 3.7e-111 371.2 16.2 1.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 ORY04997.1 - 0.026 14.3 0.5 0.049 13.4 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DivIVA PF05103.13 ORY04997.1 - 3.3 7.8 9.0 0.58 10.3 5.2 1.7 2 0 0 2 2 2 0 DivIVA protein TauD PF02668.16 ORY04998.1 - 5.3e-51 174.0 0.0 7.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY04998.1 - 4.3e-10 40.1 0.0 1.4e-09 38.4 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORY04998.1 - 0.054 12.6 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 CsiD Homoserine_dh PF00742.19 ORY04999.1 - 1.3e-51 175.0 0.0 1.7e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ORY04999.1 - 1.7e-19 70.6 0.0 3.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DSPc PF00782.20 ORY05000.1 - 8.8e-41 138.8 0.1 1.6e-28 99.1 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ORY05000.1 - 3.3e-06 27.4 0.1 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 Rit1 DUSP-like domain Y_phosphatase PF00102.27 ORY05000.1 - 1.4e-05 24.8 0.0 0.004 16.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY05000.1 - 0.061 13.4 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 ORY05000.1 - 0.17 11.6 0.1 1 9.0 0.0 2.3 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Acetyltransf_10 PF13673.7 ORY05001.1 - 7.7e-10 38.8 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY05001.1 - 9e-10 38.8 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY05001.1 - 5.1e-09 36.4 0.0 7.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY05001.1 - 0.00028 20.8 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY05001.1 - 0.0022 18.1 0.1 0.027 14.5 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY05001.1 - 0.0045 17.1 0.1 0.011 15.9 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase PX PF00787.24 ORY05002.1 - 1.9e-27 95.5 0.1 2.2e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 PX domain C2 PF00168.30 ORY05003.1 - 1.2e-17 64.1 0.1 1.3e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 C2 domain DUF4497 PF14924.6 ORY05003.1 - 0.044 14.2 0.0 4.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) DUF1264 PF06884.11 ORY05004.1 - 7.5e-72 240.5 0.2 8.9e-72 240.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DB PF01682.19 ORY05004.1 - 0.059 13.7 0.5 0.1 12.9 0.5 1.3 1 0 0 1 1 1 0 DB module G6PD_C PF02781.16 ORY05005.1 - 4.2e-111 370.8 0.0 5.9e-111 370.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORY05005.1 - 3.5e-61 206.9 0.3 8.2e-61 205.7 0.3 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Arrestin_C PF02752.22 ORY05007.1 - 2e-11 44.5 0.1 1e-08 35.7 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY05007.1 - 1.2e-07 31.8 0.0 5.5e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY05008.1 - 2.7e-13 50.5 0.4 1.1e-10 42.0 0.3 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY05008.1 - 2.2e-06 27.8 0.1 6.4e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pro_isomerase PF00160.21 ORY05009.1 - 8.3e-45 152.9 0.0 2.2e-44 151.5 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 ORY05009.1 - 0.014 15.8 0.1 0.014 15.8 0.1 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) LrgB PF04172.16 ORY05010.1 - 3.5e-45 154.2 5.3 3.5e-45 154.2 5.3 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 ORY05010.1 - 7.4e-05 22.6 7.8 7.4e-05 22.6 7.8 3.1 5 0 0 5 5 5 1 LrgA family DUF3493 PF11998.8 ORY05010.1 - 0.033 14.3 0.7 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 PUD1_2 PF18457.1 ORY05010.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 DUF1514 PF07438.11 ORY05010.1 - 0.16 11.9 1.4 5.4 7.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) SRR1 PF07985.12 ORY05011.1 - 1e-13 51.1 0.1 1.8e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 SRR1 DUF2457 PF10446.9 ORY05012.1 - 0.044 12.9 13.8 0.054 12.6 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.9 ORY05012.1 - 0.052 11.3 3.6 0.06 11.1 3.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 ORY05012.1 - 0.12 11.7 12.1 0.14 11.5 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 ORY05012.1 - 0.17 11.2 6.4 0.19 11.0 6.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY05012.1 - 0.26 10.7 9.6 0.28 10.5 9.6 1.2 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 ORY05012.1 - 0.39 11.1 19.7 0.97 9.9 19.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 ORY05012.1 - 0.99 7.5 13.6 1.2 7.3 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY05012.1 - 1.1 7.3 19.5 1.6 6.7 19.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 ORY05012.1 - 2.2 8.0 6.6 4.4 7.0 6.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH YqfQ PF14181.6 ORY05012.1 - 2.6 8.2 4.4 4.9 7.3 4.4 1.4 1 0 0 1 1 1 0 YqfQ-like protein RXT2_N PF08595.11 ORY05012.1 - 3.2 7.8 9.7 0.4 10.7 5.2 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 ORY05012.1 - 3.3 7.4 7.8 8.2 6.1 7.8 1.7 1 0 0 1 1 1 0 FAM176 family PDDEXK_6 PF04720.12 ORY05012.1 - 4.6 7.1 5.8 2.6 7.9 3.7 1.6 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Drc1-Sld2 PF11719.8 ORY05012.1 - 6.8 6.1 7.4 8 5.9 7.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein RRN3 PF05327.11 ORY05012.1 - 6.9 5.1 9.2 7.8 4.9 9.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop16 PF09420.10 ORY05013.1 - 4.5e-57 193.5 5.5 5.4e-57 193.2 5.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Exo_endo_phos PF03372.23 ORY05014.1 - 1e-08 35.0 0.1 3.3e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.19 ORY05015.1 - 9.7e-26 90.2 11.9 1.1e-25 90.0 11.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein MT PF12777.7 ORY05015.1 - 0.035 13.1 1.3 0.041 12.9 1.3 1.0 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor AhpC-TSA PF00578.21 ORY05016.1 - 6.2e-35 119.8 0.0 8.3e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY05016.1 - 1.6e-14 53.9 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY05016.1 - 1.8e-12 46.9 0.0 4.3e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin NUDIX PF00293.28 ORY05017.1 - 2.9e-12 46.8 0.0 3.5e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain PX PF00787.24 ORY05018.1 - 0.00057 19.8 0.3 0.0016 18.4 0.3 1.8 1 1 0 1 1 1 1 PX domain PB1 PF00564.24 ORY05018.1 - 0.0073 16.2 0.3 0.018 15.0 0.3 1.7 1 1 0 1 1 1 1 PB1 domain DUF4381 PF14316.6 ORY05019.1 - 0.0017 18.6 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) TMEM190 PF15431.6 ORY05019.1 - 0.0054 16.9 0.4 0.0054 16.9 0.4 1.9 2 0 0 2 2 2 1 Transmembrane protein 190 DUF443 PF04276.12 ORY05019.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) EphA2_TM PF14575.6 ORY05019.1 - 0.031 15.2 0.1 0.067 14.1 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 ORY05019.1 - 0.032 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF5305 PF17231.2 ORY05019.1 - 0.034 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Chordopox_A13L PF05961.11 ORY05019.1 - 0.064 13.5 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Stevor PF17410.2 ORY05019.1 - 0.082 12.4 1.1 0.15 11.6 0.5 1.4 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF997 PF06196.12 ORY05019.1 - 0.14 12.2 2.0 0.21 11.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Phage_holin_3_6 PF07332.11 ORY05019.1 - 0.23 11.5 0.4 0.34 11.0 0.0 1.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Adeno_E3_CR2 PF02439.15 ORY05019.1 - 1.1 9.1 7.3 2 8.3 7.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PB1 PF00564.24 ORY05020.1 - 0.0002 21.2 0.0 0.061 13.3 0.0 2.6 2 0 0 2 2 2 2 PB1 domain Glyco_hydro_46 PF01374.18 ORY05022.1 - 1.8e-33 116.0 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 RhoGAP PF00620.27 ORY05023.1 - 9.1e-36 123.0 0.1 1.2e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain Ferritin PF00210.24 ORY05024.1 - 5.3e-40 136.6 0.3 6.1e-40 136.4 0.3 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ORY05024.1 - 1.6e-07 31.8 0.1 2e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Rubrerythrin FCH PF00611.23 ORY05024.1 - 0.1 12.9 0.3 0.19 12.1 0.3 1.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Sel1 PF08238.12 ORY05025.1 - 1.3e-24 86.1 4.9 1.5e-07 31.8 0.5 4.2 4 0 0 4 4 4 4 Sel1 repeat Ribosomal_L5e PF17144.4 ORY05026.1 - 1.3e-86 288.6 0.3 1.3e-86 288.6 0.3 2.6 3 0 0 3 3 3 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORY05026.1 - 1.3e-31 109.4 8.9 1.3e-31 109.4 8.9 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region G-alpha PF00503.20 ORY05031.1 - 7e-119 397.1 1.2 8.1e-119 396.9 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY05031.1 - 6.7e-15 55.0 4.0 3.6e-10 39.6 0.1 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family MCM PF00493.23 ORY05031.1 - 0.00047 19.3 0.1 0.00081 18.6 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain zf-CHC2 PF01807.20 ORY05031.1 - 0.00064 19.5 0.1 0.0031 17.3 0.0 2.1 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ORY05031.1 - 0.0014 18.1 5.1 0.02 14.3 0.1 2.9 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region KIND PF16474.5 ORY05031.1 - 0.0039 17.1 0.0 0.0098 15.8 0.0 1.7 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain AAA_29 PF13555.6 ORY05031.1 - 0.02 14.7 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORY05031.1 - 0.032 14.4 0.2 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ORY05031.1 - 0.071 13.4 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY05031.1 - 0.096 12.2 0.3 6.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 ORY05031.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ORY05031.1 - 0.16 12.0 0.2 11 6.1 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Sin_N PF04801.13 ORY05032.1 - 1.5e-53 182.6 3.2 1.8e-53 182.3 3.2 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region SURF4 PF02077.15 ORY05034.1 - 1.6e-89 300.1 7.0 1.8e-89 299.9 7.0 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 ORY05034.1 - 5.6 7.1 13.3 0.19 11.9 3.6 2.7 2 2 1 3 3 3 0 HR-like lesion-inducing SURF4 PF02077.15 ORY05035.1 - 1.3e-91 306.9 6.1 1.4e-91 306.8 6.1 1.0 1 0 0 1 1 1 1 SURF4 family DUF2173 PF09941.9 ORY05035.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Abhydrolase_3 PF07859.13 ORY05036.1 - 1.9e-38 132.5 0.0 2.5e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY05036.1 - 1.3e-13 50.6 0.0 2.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY05036.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 ORY05036.1 - 0.052 12.2 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 ORY05036.1 - 0.11 12.0 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Amidohydro_1 PF01979.20 ORY05037.1 - 2.4e-70 237.5 1.7 3.6e-70 237.0 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY05037.1 - 3.7e-57 191.9 2.3 8.1e-57 190.8 2.3 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 ORY05037.1 - 1.3e-39 134.4 0.2 3e-39 133.3 0.2 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 ORY05037.1 - 2.2e-38 130.2 0.0 4.7e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 ORY05037.1 - 2.7e-06 27.2 0.1 1.1e-05 25.1 0.0 2.1 2 1 0 2 2 2 1 Amidohydrolase family MFS_1 PF07690.16 ORY05038.1 - 2.3e-17 63.0 26.0 3.1e-17 62.5 26.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY05038.1 - 8.7e-14 51.5 9.3 8.7e-14 51.5 9.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORY05038.1 - 6.9e-05 21.9 0.3 0.027 13.3 5.8 2.0 1 1 1 2 2 2 1 MFS_1 like family PUCC PF03209.15 ORY05038.1 - 0.11 11.5 12.3 0.049 12.6 8.9 2.1 2 1 1 3 3 3 0 PUCC protein CPP1-like PF11833.8 ORY05038.1 - 10 5.7 6.4 1.9 8.1 2.4 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pirin PF02678.16 ORY05085.1 - 6.6e-32 109.7 0.1 1.7e-31 108.4 0.1 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORY05085.1 - 5.5e-29 100.6 0.0 5.1e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORY05085.1 - 0.002 17.8 2.3 0.06 13.1 0.9 2.4 2 0 0 2 2 2 1 Cupin domain LPMO_10 PF03067.15 ORY05086.1 - 2.1e-06 28.5 0.0 6.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY05086.1 - 0.0013 18.7 0.0 0.02 14.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4987 PF16377.5 ORY05086.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF2009 PF09418.10 ORY05086.1 - 0.071 12.2 0.1 0.093 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) TMF_TATA_bd PF12325.8 ORY05087.1 - 0.016 15.5 13.6 0.016 15.5 13.6 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 ORY05087.1 - 0.032 15.1 40.7 0.28 12.1 11.6 4.8 2 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain RBD-FIP PF09457.10 ORY05087.1 - 0.048 13.6 0.1 0.048 13.6 0.1 2.6 3 0 0 3 3 3 0 FIP domain DUF2205 PF10224.9 ORY05087.1 - 0.14 12.1 0.3 0.14 12.1 0.3 4.7 3 2 2 5 5 5 0 Short coiled-coil protein ZapB PF06005.12 ORY05087.1 - 0.46 11.0 0.1 0.46 11.0 0.1 5.9 2 1 2 4 4 4 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 ORY05087.1 - 3 7.9 41.8 0.59 10.2 20.1 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 ORY05087.1 - 4.9 7.7 46.3 1.1 9.8 7.9 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF3450 PF11932.8 ORY05087.1 - 5 6.4 34.8 0.056 12.7 10.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) O-FucT PF10250.9 ORY05088.1 - 1.5e-05 24.9 1.7 0.0018 18.0 1.7 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Dynamin_N PF00350.23 ORY05089.1 - 1.8e-45 155.0 0.0 3.9e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORY05089.1 - 4.6e-15 55.6 3.1 2.8e-14 53.0 0.2 2.6 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 ORY05089.1 - 2.8e-05 24.1 0.0 0.00011 22.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NVEALA PF14055.6 ORY05089.1 - 0.15 12.0 0.1 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 NVEALA protein PHP PF02811.19 ORY05089.1 - 0.15 12.3 0.0 37 4.6 0.0 2.7 3 0 0 3 3 3 0 PHP domain AAA_15 PF13175.6 ORY05089.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain CKS PF01111.19 ORY05090.1 - 6.1e-35 119.3 0.4 9.2e-35 118.7 0.4 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DEAD PF00270.29 ORY05091.1 - 6.4e-47 159.6 0.0 1.4e-46 158.4 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY05091.1 - 4.1e-24 85.1 0.0 2.2e-22 79.5 0.1 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY05091.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 ORY05091.1 - 0.19 12.2 0.5 0.95 9.9 0.2 2.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HMG_box PF00505.19 ORY05092.1 - 1.7e-24 86.0 10.1 1.6e-13 50.8 0.7 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY05092.1 - 1.4e-16 60.8 9.2 1.5e-08 35.1 3.2 2.5 2 0 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 ORY05092.1 - 0.01 16.0 4.2 0.59 10.3 0.6 2.6 1 1 2 3 3 3 0 Protamine and protamine like DUF4872 PF16169.5 ORY05092.1 - 0.013 15.2 0.3 2.4 7.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) RepB-RCR_reg PF10723.9 ORY05092.1 - 0.031 14.2 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB AdoMet_MTase PF07757.13 ORY05092.1 - 0.097 13.0 0.9 8.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase KRAB PF01352.27 ORY05092.1 - 0.12 12.1 2.6 3.1 7.5 0.4 2.3 2 0 0 2 2 2 0 KRAB box DUF4473 PF14747.6 ORY05092.1 - 0.12 13.0 1.9 0.27 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF349 PF03993.12 ORY05092.1 - 0.55 10.6 7.5 0.99 9.7 0.3 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) PAS_3 PF08447.12 ORY05093.1 - 7.8e-12 45.3 0.0 5.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORY05093.1 - 8e-07 29.0 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY05093.1 - 1.3e-06 28.6 0.0 0.00029 21.1 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORY05093.1 - 0.00075 19.7 0.0 1 9.6 0.0 2.5 3 0 0 3 3 3 2 PAS fold DUF5589 PF17672.1 ORY05093.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5589) PAS_11 PF14598.6 ORY05093.1 - 0.078 13.1 0.0 10 6.3 0.0 2.2 2 0 0 2 2 2 0 PAS domain Cyclin PF08613.11 ORY05095.1 - 7.9e-11 42.6 0.0 8.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY05095.1 - 8.2e-11 41.7 0.0 1.7e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Phenol_monoox PF04663.12 ORY05095.1 - 0.027 14.6 0.3 0.059 13.5 0.3 1.6 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Prp19 PF08606.11 ORY05096.1 - 3.7e-35 119.7 2.4 3.7e-35 119.7 2.4 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 ORY05096.1 - 1.8e-33 114.0 3.1 8.3e-08 32.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY05096.1 - 6e-13 48.9 0.2 0.026 14.8 0.0 5.5 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 ORY05096.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ge1_WD40 PF16529.5 ORY05096.1 - 0.00015 20.9 0.3 1.2 8.0 0.0 4.0 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein U-box PF04564.15 ORY05096.1 - 0.00016 21.7 0.1 0.0005 20.2 0.0 1.8 2 0 0 2 2 2 1 U-box domain Cytochrom_D1 PF02239.16 ORY05096.1 - 0.0038 15.8 0.3 0.11 11.0 0.1 2.5 1 1 2 3 3 3 1 Cytochrome D1 heme domain PSII_BNR PF14870.6 ORY05096.1 - 0.018 14.3 0.3 0.053 12.8 0.1 1.7 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Rtf2 PF04641.12 ORY05096.1 - 0.031 13.7 1.3 0.17 11.2 0.0 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger HPS3_N PF14761.6 ORY05096.1 - 0.033 13.7 0.0 0.17 11.4 0.0 2.1 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 Nup188 PF10487.9 ORY05096.1 - 0.099 10.5 0.9 0.13 10.1 0.9 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF4407 PF14362.6 ORY05096.1 - 0.11 11.8 3.6 0.15 11.4 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dynactin_p22 PF07426.11 ORY05096.1 - 0.11 12.3 1.7 13 5.6 0.4 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 Gaa1 PF04114.14 ORY05097.1 - 1.2e-122 410.5 5.7 1.7e-122 410.0 5.7 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF382 PF04037.13 ORY05098.1 - 3.2e-59 198.6 1.9 3.2e-59 198.6 1.9 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 ORY05098.1 - 7e-21 73.8 6.1 1.4e-20 72.8 6.1 1.6 1 0 0 1 1 1 1 PSP Pro_isomerase PF00160.21 ORY05099.1 - 1.6e-40 138.9 0.0 2.3e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORY05100.1 - 6.4e-06 26.8 0.1 0.013 16.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY05100.1 - 0.00016 20.8 0.2 0.36 9.8 0.0 2.4 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 ORY05100.1 - 0.00078 19.7 0.0 0.054 13.8 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S28e PF01200.18 ORY05101.1 - 1.2e-33 114.9 1.0 1.3e-33 114.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 ORY05101.1 - 0.039 14.3 0.0 0.042 14.2 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal S_layer_C PF05124.12 ORY05101.1 - 0.054 13.5 0.0 0.054 13.5 0.0 1.0 1 0 0 1 1 1 0 S-layer like family, C-terminal region Ribosomal_S11 PF00411.19 ORY05102.1 - 1.4e-47 160.7 1.3 1.7e-47 160.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S4e PF00900.20 ORY05103.1 - 1.9e-36 123.8 0.1 3.9e-36 122.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY05103.1 - 2.1e-26 91.3 0.1 3.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY05103.1 - 2.4e-21 75.5 6.1 5.5e-21 74.4 6.1 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY05103.1 - 1.4e-08 34.3 0.1 3.3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 ORY05103.1 - 4.9e-05 23.1 7.7 7.2e-05 22.6 5.4 2.5 2 0 0 2 2 2 1 KOW motif MMM1 PF10296.9 ORY05104.1 - 1.4e-08 34.2 0.1 7.4e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 GP3 PF03076.14 ORY05104.1 - 0.11 12.5 0.9 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Equine arteritis virus GP3 Ribosomal_L14e PF01929.17 ORY05105.1 - 9.7e-32 109.3 3.0 1.6e-31 108.6 3.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORY05105.1 - 0.0012 18.7 0.3 0.0023 17.8 0.3 1.5 1 0 0 1 1 1 1 KOW motif Cyclin_N PF00134.23 ORY05106.1 - 4.3e-10 39.4 0.0 5.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY05106.1 - 5.2e-06 26.9 0.0 5.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin DUF3421 PF11901.8 ORY05107.1 - 2.3e-21 75.9 1.9 1.4e-10 41.1 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) PLA2G12 PF06951.11 ORY05108.1 - 1.1e-05 25.4 13.8 2.5e-05 24.3 13.8 1.7 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) EF-hand_12 PF17901.1 ORY05108.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 EF-hand fold domain Arrestin_N PF00339.29 ORY05109.1 - 2.4e-12 47.1 1.9 2e-09 37.7 0.1 3.3 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY05109.1 - 1.9e-11 44.6 1.8 7.1e-08 33.0 0.9 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY05109.1 - 0.0022 17.7 0.0 0.0053 16.5 0.0 1.7 1 1 0 1 1 1 1 Arrestin_N terminal like Spo0M PF07070.11 ORY05109.1 - 0.038 13.5 0.0 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 SpoOM protein DUF4502 PF14950.6 ORY05110.1 - 4.9e-08 32.8 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) CDP-OH_P_transf PF01066.21 ORY05111.1 - 1.2e-17 64.4 0.1 1.2e-17 64.4 0.1 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TFIIS_C PF01096.18 ORY05112.1 - 2.3e-17 62.6 1.8 2.3e-17 62.6 1.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY05112.1 - 7.1e-06 25.8 12.9 0.0019 18.0 1.0 3.3 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 ORY05112.1 - 0.0069 15.9 14.0 0.068 12.7 1.1 3.4 2 2 1 3 3 3 3 TFIIB zinc-binding DZR PF12773.7 ORY05112.1 - 0.007 16.4 11.9 8.6 6.5 11.9 3.3 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 ORY05112.1 - 0.024 15.0 9.6 0.026 14.9 0.9 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar Prok-RING_1 PF14446.6 ORY05112.1 - 0.041 13.8 9.7 0.12 12.4 1.1 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-TFIIB PF13453.6 ORY05112.1 - 0.048 13.0 0.9 0.048 13.0 0.9 2.0 2 1 0 2 2 2 0 Transcription factor zinc-finger PNP_UDP_1 PF01048.20 ORY05112.1 - 0.054 12.7 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphorylase superfamily Ogr_Delta PF04606.12 ORY05112.1 - 0.057 13.4 1.5 0.057 13.4 1.5 2.1 2 0 0 2 2 1 0 Ogr/Delta-like zinc finger HypA PF01155.19 ORY05112.1 - 0.075 13.1 7.0 89 3.2 7.0 3.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_LEF5_C PF11792.8 ORY05112.1 - 0.078 12.7 0.1 0.078 12.7 0.1 3.0 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain eIF-5_eIF-2B PF01873.17 ORY05112.1 - 0.095 12.6 0.4 0.095 12.6 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 tRNA-synt_1f PF01921.18 ORY05112.1 - 0.13 11.1 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) zf-RRN7 PF11781.8 ORY05112.1 - 0.14 11.9 5.8 15 5.4 1.9 4.0 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nop10p PF04135.12 ORY05112.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.4 2 1 1 3 3 2 0 Nucleolar RNA-binding protein, Nop10p family C1_1 PF00130.22 ORY05112.1 - 0.22 11.5 6.9 1.1 9.1 0.9 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 ORY05112.1 - 0.24 11.5 14.6 2 8.6 0.3 4.1 4 0 0 4 4 4 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 ORY05112.1 - 0.25 11.1 15.2 0.36 10.6 3.0 3.7 3 1 0 3 3 3 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 ORY05112.1 - 0.3 11.6 6.1 0.57 10.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain MqsA_antitoxin PF15731.5 ORY05112.1 - 0.3 11.2 2.2 6.6 6.9 0.5 2.2 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Zn_ribbon_recom PF13408.6 ORY05112.1 - 0.35 11.4 13.9 2.3 8.8 1.7 3.4 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.6 ORY05112.1 - 0.51 10.3 11.8 5.9 6.9 1.6 3.9 2 2 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 ORY05112.1 - 0.54 9.7 20.6 0.34 10.4 0.4 4.3 4 1 0 4 4 4 0 zinc-ribbon domain RPA_interact_C PF14768.6 ORY05112.1 - 0.6 10.7 7.3 4.6 7.9 7.3 2.2 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Mu-like_Com PF10122.9 ORY05112.1 - 0.74 9.3 0.1 0.74 9.3 0.1 2.9 3 1 0 3 3 3 0 Mu-like prophage protein Com zf-C3HC4_3 PF13920.6 ORY05112.1 - 1.1 9.2 8.6 1.6 8.6 1.2 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.13 ORY05112.1 - 1.1 9.3 11.5 0.23 11.5 2.5 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 ORY05112.1 - 1.6 8.7 7.6 18 5.3 2.6 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.13 ORY05112.1 - 1.6 8.5 16.3 6 6.6 3.9 3.9 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 ORY05112.1 - 2 8.2 23.6 2.3 8.0 0.1 4.1 4 1 0 4 4 3 0 zinc-ribbon domain DUF3268 PF11672.8 ORY05112.1 - 2.3 8.6 6.4 0.65 10.3 1.1 2.2 2 1 0 2 2 2 0 zinc-finger-containing domain zf_C2H2_10 PF18414.1 ORY05112.1 - 3 7.5 5.1 9.7 5.8 0.2 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger zf_UBZ PF18439.1 ORY05112.1 - 3.3 7.4 8.2 36 4.1 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-HYPF PF07503.12 ORY05112.1 - 3.9 7.3 11.5 1.1 9.1 0.1 3.8 4 0 0 4 4 4 0 HypF finger zf-CSL PF05207.13 ORY05112.1 - 4.9 7.0 9.9 2.4 7.9 1.8 2.9 2 2 0 2 2 2 0 CSL zinc finger Zn_ribbon_SprT PF17283.2 ORY05112.1 - 6.1 6.8 9.9 11 6.1 0.9 3.8 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 ORY05112.1 - 6.5 6.9 13.7 5.1 7.3 0.2 3.3 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 PhnA_Zn_Ribbon PF08274.12 ORY05112.1 - 8 6.5 12.3 12 6.0 0.4 3.9 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 ORY05112.1 - 8.4 6.5 8.6 1.8 8.6 2.2 2.9 3 1 0 3 3 3 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 ORY05112.1 - 9.8 6.1 15.6 0.25 11.2 4.8 3.4 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger RNA_polI_A34 PF08208.11 ORY05113.1 - 3.2e-27 96.0 3.6 3.8e-27 95.7 3.6 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase PF00069.25 ORY05114.1 - 7.7e-41 140.2 0.2 1.3e-21 77.2 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05114.1 - 6.1e-14 51.9 0.1 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SMN PF06003.12 ORY05114.1 - 0.035 13.3 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) WD40 PF00400.32 ORY05115.1 - 1.4e-67 222.0 19.3 9e-11 42.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY05115.1 - 3.3e-24 85.0 2.3 1.3e-05 25.4 0.1 6.1 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY05115.1 - 2.5e-18 66.0 7.3 0.00051 18.8 0.0 5.9 2 2 4 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY05115.1 - 5.5e-14 52.5 1.7 1.1e-06 28.7 0.2 3.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY05115.1 - 1.6e-08 34.3 0.1 0.00015 21.2 0.0 3.6 2 1 2 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 ORY05115.1 - 2.6e-08 33.2 5.5 0.0017 17.4 0.0 4.6 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 ORY05115.1 - 2e-07 30.3 3.8 0.49 9.3 0.0 5.0 1 1 4 5 5 5 4 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 ORY05115.1 - 8e-05 21.1 0.0 0.0021 16.5 0.0 2.5 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 ORY05115.1 - 0.0026 16.9 1.0 16 4.5 0.0 4.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 ORY05115.1 - 0.0028 16.5 3.6 0.69 8.6 0.1 4.0 1 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 ORY05115.1 - 0.0041 15.7 0.1 0.37 9.3 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 ORY05115.1 - 0.0097 15.0 3.0 0.059 12.4 0.6 2.7 1 1 2 3 3 3 1 Coatomer WD associated region Nbas_N PF15492.6 ORY05115.1 - 0.013 14.8 1.2 7.5 5.8 0.1 3.6 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 ORY05115.1 - 0.024 13.7 0.0 0.2 10.7 0.0 2.2 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Ricin_B_lectin PF00652.22 ORY05115.1 - 0.027 14.7 0.5 0.089 13.0 0.0 2.1 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain IKI3 PF04762.12 ORY05115.1 - 0.028 12.5 0.1 0.056 11.4 0.1 1.5 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.12 ORY05115.1 - 0.03 14.3 1.2 3.9 7.5 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Hira PF07569.11 ORY05115.1 - 0.06 13.1 2.3 31 4.2 0.0 4.2 3 1 1 4 4 4 0 TUP1-like enhancer of split Hexapep PF00132.24 ORY05116.1 - 2.5e-12 46.0 19.2 2.9e-08 33.1 2.5 4.6 3 2 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY05116.1 - 9.8e-07 28.4 14.0 1.6e-05 24.5 0.7 4.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY05116.1 - 6.4e-05 22.1 1.1 0.00012 21.2 0.1 1.7 2 0 0 2 2 2 1 L-fucokinase DUF4954 PF16314.5 ORY05116.1 - 2.9 5.9 4.0 1.2 7.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Ribosomal_L6 PF00347.23 ORY05117.1 - 7.4e-32 109.9 3.8 1.7e-17 63.8 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Anoctamin PF04547.12 ORY05118.1 - 5.1e-104 348.6 17.9 6.3e-104 348.3 17.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 ORY05118.1 - 4.7e-05 23.2 0.4 0.0084 15.8 0.1 3.0 3 0 0 3 3 3 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Claudin_3 PF06653.11 ORY05118.1 - 0.0009 19.2 1.9 0.0009 19.2 1.9 2.3 2 0 0 2 2 2 1 Tight junction protein, Claudin-like AAA PF00004.29 ORY05119.1 - 4.2e-42 143.7 0.0 7.2e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY05119.1 - 2.7e-10 39.9 0.1 6e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY05119.1 - 3.6e-05 24.2 0.9 0.013 15.9 0.1 3.3 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ORY05119.1 - 8.2e-05 22.4 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY05119.1 - 0.00014 22.2 0.2 0.014 15.6 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY05119.1 - 0.00016 21.7 0.1 0.0015 18.6 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY05119.1 - 0.00021 20.6 0.1 0.00061 19.1 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 ORY05119.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 ORY05119.1 - 0.0029 18.2 0.0 0.0086 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY05119.1 - 0.0034 17.5 0.0 0.0075 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY05119.1 - 0.0035 17.1 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY05119.1 - 0.0051 17.2 0.0 0.022 15.2 0.0 2.1 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 ORY05119.1 - 0.0088 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ORY05119.1 - 0.015 15.4 0.0 0.12 12.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY05119.1 - 0.035 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PELOTA_1 PF15608.6 ORY05119.1 - 0.064 13.2 0.3 0.19 11.7 0.3 1.8 1 0 0 1 1 1 0 PELOTA RNA binding domain AAA_28 PF13521.6 ORY05119.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY05119.1 - 0.1 11.8 0.1 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 ORY05119.1 - 0.1 11.7 0.0 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 ORY05119.1 - 0.16 11.4 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 ORY05119.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORY05119.1 - 0.21 12.1 0.8 0.94 10.0 0.1 2.5 2 1 0 2 2 2 0 ABC transporter Autophagy_act_C PF03987.15 ORY05120.1 - 1.8e-12 47.6 0.0 2.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Arginase PF00491.21 ORY05121.1 - 1.3e-74 251.2 0.0 1.5e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Arf PF00025.21 ORY05122.1 - 1.3e-75 252.6 0.0 1.6e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY05122.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY05122.1 - 2.5e-12 46.7 0.0 2.9e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY05122.1 - 6.2e-11 42.1 0.0 7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORY05122.1 - 7.6e-11 41.8 0.1 2.7e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY05122.1 - 3.3e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY05122.1 - 3.7e-05 23.8 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY05122.1 - 0.00057 19.5 0.0 0.0049 16.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 ORY05122.1 - 0.023 15.3 0.0 0.034 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY05122.1 - 0.06 12.9 0.1 9 5.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORY05122.1 - 0.12 12.9 0.2 0.16 12.5 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORY05122.1 - 0.16 11.6 0.1 0.18 11.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain Peptidase_A22B PF04258.13 ORY05123.1 - 9.1e-85 284.6 11.9 1.2e-84 284.2 11.9 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 ORY05123.1 - 0.001 18.6 6.2 0.001 18.6 6.2 2.1 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 ORY05123.1 - 0.017 13.9 1.3 0.017 13.9 1.3 2.7 2 1 0 2 2 2 0 Presenilin UNC-79 PF14776.6 ORY05123.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Aldolase_II PF00596.21 ORY05124.1 - 2.6e-45 154.7 0.0 3.1e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FA_desaturase PF00487.24 ORY05125.1 - 5.5e-21 75.6 16.3 9.4e-21 74.8 16.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 ORY05125.1 - 4e-12 45.4 0.4 9.8e-12 44.2 0.4 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) TLD PF07534.16 ORY05126.1 - 6.1e-22 78.3 0.0 1.3e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 TLD CorA PF01544.18 ORY05127.1 - 2.2e-45 155.2 3.1 2.6e-45 155.0 3.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC22 PF04573.12 ORY05128.1 - 2.6e-49 167.0 0.0 2.9e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Chs7 PF12271.8 ORY05129.1 - 2.2e-78 263.6 21.4 2.4e-78 263.4 21.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone SLAC1 PF03595.17 ORY05129.1 - 0.62 9.3 25.8 0.98 8.6 25.8 1.3 1 1 0 1 1 1 0 Voltage-dependent anion channel ATP-synt_J PF04911.12 ORY05129.1 - 7.5 6.2 5.4 15 5.3 0.0 3.5 3 0 0 3 3 3 0 ATP synthase j chain Cyclin PF08613.11 ORY05130.1 - 3.7e-11 43.7 0.6 6.1e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY05130.1 - 0.012 15.3 0.3 0.024 14.4 0.4 1.4 1 1 0 1 1 1 0 Cyclin, N-terminal domain CLPTM1 PF05602.12 ORY05131.1 - 5.9e-100 335.3 1.4 7.2e-100 335.0 1.4 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 ORY05131.1 - 0.00077 19.2 0.1 0.00077 19.2 0.1 3.4 3 1 0 3 3 3 1 PQ loop repeat ER_lumen_recept PF00810.18 ORY05131.1 - 4.5 8.1 10.4 2.9 8.7 5.7 2.6 2 1 0 2 2 2 0 ER lumen protein retaining receptor F-box-like PF12937.7 ORY05132.1 - 0.015 15.1 0.2 0.039 13.8 0.2 1.7 1 0 0 1 1 1 0 F-box-like tRNA-synt_1c PF00749.21 ORY05133.1 - 3.7e-114 380.8 0.0 8.1e-114 379.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 ORY05133.1 - 4e-53 179.7 1.6 6.5e-53 179.0 1.6 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 ORY05133.1 - 8.6e-40 136.4 0.7 1.4e-38 132.5 0.2 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 ORY05133.1 - 7.7e-13 49.2 3.8 2.2e-12 47.7 3.8 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SH3_9 PF14604.6 ORY05134.1 - 4.3e-12 45.7 0.3 1.2e-10 41.1 0.0 3.1 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.28 ORY05134.1 - 1.6e-07 30.8 0.0 5.3e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORY05134.1 - 0.0014 18.3 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY05135.1 - 1e-11 44.2 0.0 1.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY05135.1 - 3.4e-08 33.2 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY05135.1 - 3e-06 26.8 0.0 4.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DapB_C PF05173.14 ORY05135.1 - 0.075 13.1 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus MRVI1 PF05781.12 ORY05135.1 - 0.15 10.7 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 MRVI1 protein MFS_1 PF07690.16 ORY05136.1 - 2.6e-26 92.4 42.0 7e-17 61.4 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_1 PF01979.20 ORY05201.1 - 1.4e-56 192.3 0.0 1.7e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY05201.1 - 0.00036 20.1 0.0 0.3 10.5 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family FAD_binding_4 PF01565.23 ORY05201.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Transket_pyr PF02779.24 ORY05202.1 - 2.6e-48 164.1 0.0 4e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORY05202.1 - 6.1e-48 162.4 0.1 2.6e-47 160.3 0.0 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORY05202.1 - 1.3e-40 139.2 0.1 6.4e-40 137.0 0.0 2.0 2 0 0 2 2 2 1 Dehydrogenase E1 component Motile_Sperm PF00635.26 ORY05203.1 - 3.1e-09 36.7 0.0 5.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FKBP_C PF00254.28 ORY05204.1 - 1e-33 115.5 0.0 2e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 ORY05204.1 - 2.5e-27 94.5 0.6 4e-27 93.8 0.6 1.3 1 0 0 1 1 1 1 Basic tilted helix bundle domain Evr1_Alr PF04777.13 ORY05205.1 - 1.6e-30 105.5 1.5 1.9e-30 105.2 1.5 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Herpes_UL69 PF05459.12 ORY05205.1 - 0.057 12.8 0.1 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Herpesvirus transcriptional regulator family APOBEC4 PF18775.1 ORY05205.1 - 0.07 13.3 0.3 0.14 12.3 0.3 1.7 1 1 0 1 1 1 0 APOBEC4 Actin PF00022.19 ORY05206.1 - 2.3e-116 388.8 0.0 1.1e-115 386.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY05206.1 - 0.0085 15.0 0.0 0.025 13.4 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein PMT PF02366.18 ORY05207.1 - 2.3e-85 286.1 16.3 3.8e-85 285.4 16.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY05207.1 - 6e-59 199.0 8.4 6e-59 199.0 8.4 3.1 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY05207.1 - 3.7e-15 56.3 0.0 6.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF962 PF06127.11 ORY05207.1 - 0.28 11.3 2.8 1.9 8.6 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Homeodomain PF00046.29 ORY05208.1 - 1.4e-19 69.6 2.8 2e-19 69.2 2.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY05208.1 - 0.0026 17.6 0.1 0.0049 16.8 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORY05208.1 - 0.086 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Aminotran_4 PF01063.19 ORY05209.1 - 2.9e-27 96.0 0.0 3.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Tyrosinase PF00264.20 ORY05210.1 - 2.7e-38 132.5 6.1 3.5e-37 128.8 6.1 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase TPT PF03151.16 ORY05212.1 - 2.7e-29 102.4 25.6 3.2e-29 102.2 25.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY05212.1 - 9.7e-10 38.8 35.4 2.3e-05 24.6 10.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY05212.1 - 6e-05 22.4 27.2 8.5e-05 21.9 27.2 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ORY05212.1 - 1.6 7.8 20.3 24 4.0 20.3 2.3 1 1 0 1 1 1 0 Nucleotide-sugar transporter Peptidase_S24 PF00717.23 ORY05213.1 - 6.5e-10 38.8 0.0 1.4e-09 37.8 0.0 1.6 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 ORY05213.1 - 1.4e-07 31.4 0.0 0.00021 21.1 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Homeodomain PF00046.29 ORY05214.1 - 1.2e-16 60.3 7.7 1.3e-16 60.2 7.7 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY05214.1 - 2e-05 24.4 0.5 3.9e-05 23.5 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 ORY05214.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain RabGAP-TBC PF00566.18 ORY05215.1 - 1.5e-52 178.4 0.0 1.9e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spt4 PF06093.13 ORY05216.1 - 2e-32 111.1 1.3 2.4e-32 110.9 1.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger AAA PF00004.29 ORY05217.1 - 5.2e-54 182.2 0.0 1.4e-35 122.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 ORY05217.1 - 3.8e-24 84.9 0.2 1.2e-23 83.3 0.2 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 ORY05217.1 - 1.2e-12 47.5 0.2 3.2e-05 23.7 0.0 2.9 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY05217.1 - 2.1e-10 41.3 4.0 0.00035 21.0 0.5 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORY05217.1 - 3.3e-08 33.9 0.4 0.0029 17.9 0.1 3.6 2 2 1 3 3 3 2 AAA domain NACHT PF05729.12 ORY05217.1 - 1.1e-07 31.9 0.1 0.0035 17.3 0.0 3.7 2 2 1 3 3 3 2 NACHT domain PEX-2N PF09263.10 ORY05217.1 - 5.7e-07 29.8 0.0 2.2e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal T2SSE PF00437.20 ORY05217.1 - 1.7e-05 24.1 0.0 0.00019 20.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 ORY05217.1 - 2e-05 24.9 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 ORY05217.1 - 5.3e-05 23.2 0.1 0.015 15.2 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORY05217.1 - 6.2e-05 22.8 0.0 0.0087 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ORY05217.1 - 7.5e-05 22.9 0.0 0.62 10.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 ORY05217.1 - 8e-05 22.5 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 ORY05217.1 - 0.00014 22.4 0.0 0.33 11.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY05217.1 - 0.00014 22.0 0.0 0.25 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORY05217.1 - 0.00017 21.6 0.0 0.03 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ORY05217.1 - 0.00022 20.6 0.0 0.049 12.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 ORY05217.1 - 0.0004 20.2 0.0 0.087 12.6 0.0 3.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 ORY05217.1 - 0.00053 19.2 0.0 0.47 9.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 ORY05217.1 - 0.00071 19.2 1.1 7.4 6.1 0.0 4.1 3 1 1 4 4 4 0 AAA domain Molydop_binding PF01568.21 ORY05217.1 - 0.001 19.1 0.0 2.2 8.4 0.0 3.5 3 0 0 3 3 3 1 Molydopterin dinucleotide binding domain AAA_17 PF13207.6 ORY05217.1 - 0.0013 19.2 0.0 0.53 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY05217.1 - 0.0015 18.5 0.0 1.9 8.5 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 ORY05217.1 - 0.0024 17.9 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORY05217.1 - 0.0025 18.4 0.0 0.48 11.0 0.0 3.2 3 0 0 3 3 2 1 ABC transporter Mg_chelatase PF01078.21 ORY05217.1 - 0.0026 17.2 0.0 0.22 10.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 ORY05217.1 - 0.004 17.0 0.1 0.015 15.1 0.1 2.1 2 1 0 2 2 1 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 ORY05217.1 - 0.0046 17.3 0.0 0.18 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 ORY05217.1 - 0.005 16.6 0.0 0.63 9.7 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 ORY05217.1 - 0.0071 15.9 0.0 0.84 9.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 ORY05217.1 - 0.0075 15.6 0.0 2.3 7.5 0.0 2.9 3 0 0 3 3 3 1 KaiC DUF87 PF01935.17 ORY05217.1 - 0.0085 16.2 0.8 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain CDC48_2 PF02933.17 ORY05217.1 - 0.0099 15.6 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.12 ORY05217.1 - 0.014 14.6 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 ORY05217.1 - 0.016 14.4 0.0 0.4 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA12 PF10443.9 ORY05217.1 - 0.017 13.9 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein FtsK_SpoIIIE PF01580.18 ORY05217.1 - 0.03 13.7 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 ORY05217.1 - 0.057 13.1 0.0 4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY05217.1 - 0.06 12.9 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ORY05217.1 - 0.089 13.0 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain PCI PF01399.27 ORY05218.1 - 7.3e-24 84.3 1.3 7.3e-24 84.3 1.3 2.6 2 1 1 3 3 3 1 PCI domain RAMPs PF03787.15 ORY05218.1 - 0.3 11.1 1.7 0.75 9.8 1.7 1.6 1 0 0 1 1 1 0 RAMP superfamily XPG_I PF00867.18 ORY05219.1 - 3.3e-18 65.8 0.1 1e-17 64.3 0.1 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY05219.1 - 1e-12 48.4 0.0 2.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 ORY05219.1 - 0.0023 18.5 0.0 0.0076 16.8 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF4746 PF15928.5 ORY05219.1 - 0.016 14.6 0.7 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Ras PF00071.22 ORY05220.1 - 1.4e-54 184.1 0.0 1.6e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY05220.1 - 8.3e-23 80.9 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY05220.1 - 9.6e-09 34.9 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY05220.1 - 0.0037 16.8 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain W2 PF02020.18 ORY05221.1 - 5e-15 55.4 0.9 1.4e-14 54.0 0.9 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon UPF0181 PF03701.14 ORY05221.1 - 0.02 14.5 0.2 0.059 13.0 0.1 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0181) HbrB PF08539.11 ORY05221.1 - 0.029 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 HbrB-like HDNR PF15115.6 ORY05221.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif Retrotrans_gag PF03732.17 ORY05221.1 - 0.095 13.0 1.7 4.2 7.7 0.1 3.0 2 1 1 3 3 3 0 Retrotransposon gag protein Rsm22 PF09243.10 ORY05222.1 - 3.6e-69 233.1 0.0 5.3e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 ORY05222.1 - 6.7e-08 33.1 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY05222.1 - 7.6e-08 32.3 0.0 2e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY05222.1 - 1.2e-07 32.3 0.0 2.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY05222.1 - 3.5e-05 23.7 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY05222.1 - 0.00031 21.3 0.0 0.0008 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CAP_GLY PF01302.25 ORY05223.1 - 2.1e-21 75.7 0.1 3.3e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 ORY05223.1 - 3.5e-09 36.3 18.9 9e-05 22.2 12.3 2.8 2 0 0 2 2 2 2 CLIP1 zinc knuckle ATG16 PF08614.11 ORY05223.1 - 0.0074 16.5 2.5 0.0074 16.5 2.5 6.8 2 1 6 8 8 8 1 Autophagy protein 16 (ATG16) eIF3g PF12353.8 ORY05223.1 - 0.015 15.7 2.0 0.015 15.7 2.0 3.1 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G Molydop_binding PF01568.21 ORY05223.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain CdiA_C PF18451.1 ORY05223.1 - 0.27 11.5 2.6 3.3 8.0 0.1 3.1 1 1 1 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Spuma_A9PTase PF03539.14 ORY05223.1 - 0.72 10.0 3.5 0.4 10.8 0.6 2.1 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) DUF1154 PF06631.11 ORY05223.1 - 1.9 8.6 6.4 3.4 7.7 1.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1154) zf-CCHC_3 PF13917.6 ORY05223.1 - 1.9 8.5 6.3 0.18 11.8 1.2 2.0 2 0 0 2 2 2 0 Zinc knuckle Mgm101p PF06420.12 ORY05224.1 - 1.6e-82 275.1 0.0 2.6e-82 274.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF1035 PF06281.12 ORY05224.1 - 0.27 11.3 1.6 0.45 10.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) zf-C2H2 PF00096.26 ORY05225.1 - 3.7e-12 46.0 11.3 4.1e-06 26.9 1.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY05225.1 - 1.7e-08 34.6 10.1 0.00013 22.5 1.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY05225.1 - 1.8e-08 34.4 13.2 1.6e-07 31.4 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORY05225.1 - 3.1e-05 24.2 0.3 3.1e-05 24.2 0.3 2.6 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY05225.1 - 4e-05 23.5 8.7 0.0072 16.3 0.2 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY05225.1 - 0.0036 17.5 0.1 0.0036 17.5 0.1 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 ORY05225.1 - 0.029 15.0 0.8 0.41 11.3 0.1 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 ORY05225.1 - 0.21 11.8 5.8 24 5.1 5.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_SprT PF17283.2 ORY05225.1 - 0.42 10.6 5.6 0.15 12.0 1.4 2.0 2 1 0 2 2 2 0 SprT-like zinc ribbon domain CYTH PF01928.21 ORY05226.1 - 9.6e-17 61.5 0.8 1.2e-16 61.2 0.8 1.1 1 0 0 1 1 1 1 CYTH domain RAD51_interact PF15696.5 ORY05227.1 - 3.3e-05 23.9 1.2 3.3e-05 23.9 1.2 3.1 3 0 0 3 3 3 1 RAD51 interacting motif Cyclin PF08613.11 ORY05228.1 - 6.3e-12 46.2 0.1 9.2e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY05228.1 - 8e-06 25.6 0.1 1.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Keratin_2_head PF16208.5 ORY05229.1 - 0.02 15.0 10.0 0.033 14.3 10.0 1.2 1 0 0 1 1 1 0 Keratin type II head NAD_binding_1 PF00175.21 ORY05230.1 - 1.7e-32 112.3 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY05230.1 - 3.1e-23 82.0 0.0 4.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY05230.1 - 3.2e-09 37.1 0.0 8.2e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORY05230.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PPR_2 PF13041.6 ORY05232.1 - 2.3e-55 184.6 7.4 1.5e-13 50.7 0.1 9.6 4 2 5 10 10 10 10 PPR repeat family PPR_1 PF12854.7 ORY05232.1 - 7.7e-39 131.1 0.1 5.4e-07 29.2 0.0 9.8 10 0 0 10 10 10 6 PPR repeat PPR PF01535.20 ORY05232.1 - 2.2e-37 124.7 8.3 2.2e-05 24.4 0.0 12.0 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.6 ORY05232.1 - 1.5e-34 117.9 9.5 1.7e-08 34.4 0.0 8.1 2 2 5 9 9 9 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY05232.1 - 6.9e-14 51.7 0.4 0.0017 17.8 0.0 4.5 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORY05232.1 - 2.1e-10 41.0 3.9 0.00016 22.0 0.2 6.4 3 2 2 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 ORY05232.1 - 2.1e-05 25.0 0.0 5.4 7.6 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY05232.1 - 0.0012 17.8 6.9 0.63 8.8 0.6 5.1 2 1 4 6 6 6 2 Mitochondrial 28S ribosomal protein S27 CNOT1_TTP_bind PF16417.5 ORY05232.1 - 0.025 13.8 2.0 7.2 5.7 0.1 3.6 4 0 0 4 4 4 0 CCR4-NOT transcription complex subunit 1 TTP binding domain CCM2_C PF16545.5 ORY05232.1 - 0.086 13.4 0.3 20 5.8 0.0 3.8 4 1 1 5 5 5 0 Cerebral cavernous malformation protein, harmonin-homology DUF727 PF05303.12 ORY05233.1 - 1.3e-11 44.4 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) 60KD_IMP PF02096.20 ORY05234.1 - 6.1e-26 91.3 1.0 7.5e-26 91.0 1.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Sacchrp_dh_C PF16653.5 ORY05235.1 - 1.1e-86 291.2 0.0 1.8e-86 290.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 ORY05235.1 - 1.3e-28 100.0 0.2 6.8e-28 97.7 0.0 2.4 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 ORY05235.1 - 2.9e-19 69.6 0.0 6.5e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ORY05235.1 - 1.2e-05 24.8 0.0 0.0019 17.5 0.0 3.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ORY05235.1 - 6.8e-05 23.0 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 ORY05235.1 - 0.0002 21.3 0.1 0.00041 20.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Hydrolase_6 PF13344.6 ORY05236.1 - 1.1e-31 108.9 0.0 2e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY05236.1 - 1.8e-21 76.0 0.0 3.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY05236.1 - 6.7e-09 36.3 0.0 2.4e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY05236.1 - 2e-08 34.5 0.0 0.00038 20.6 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase TPT PF03151.16 ORY05238.1 - 3.2e-42 144.9 27.1 4.1e-42 144.5 27.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY05238.1 - 2.6e-10 40.6 40.9 2e-05 24.7 17.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY05238.1 - 3.5e-09 36.3 28.3 4.3e-09 36.0 28.3 1.1 1 0 0 1 1 1 1 UAA transporter family Pox_E10 PF04805.12 ORY05238.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 E10-like protein conserved region Cofilin_ADF PF00241.20 ORY05239.1 - 9.9e-26 89.9 0.1 1.1e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ADH_N PF08240.12 ORY05240.1 - 1e-29 102.6 0.8 1.5e-29 102.0 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY05240.1 - 5.9e-21 74.8 0.0 9.6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY05240.1 - 1.5e-10 40.9 0.0 4.8e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY05240.1 - 1.9e-09 38.6 0.0 4.8e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY05240.1 - 0.00055 19.3 0.1 0.00094 18.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 ORY05240.1 - 0.15 12.8 0.0 0.33 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_C14 PF00656.22 ORY05241.1 - 1.6e-57 195.3 0.2 2.4e-57 194.7 0.2 1.2 1 0 0 1 1 1 1 Caspase domain Aminotran_1_2 PF00155.21 ORY05242.1 - 1.6e-17 63.7 0.0 3.2e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Prefoldin_2 PF01920.20 ORY05243.1 - 7e-23 80.6 11.3 7.9e-23 80.4 11.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 ORY05243.1 - 3.8e-06 26.8 6.7 5.3e-06 26.3 6.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.6 ORY05243.1 - 0.00043 20.2 6.2 0.00052 20.0 6.2 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Snf7 PF03357.21 ORY05243.1 - 0.00051 19.7 2.9 0.00051 19.7 2.9 2.0 2 0 0 2 2 2 1 Snf7 CENP-F_leu_zip PF10473.9 ORY05243.1 - 0.0033 17.4 4.6 0.0033 17.4 4.6 2.2 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 ORY05243.1 - 0.0062 16.8 12.7 0.02 15.1 4.3 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 ORY05243.1 - 0.0085 16.5 2.0 0.0085 16.5 2.0 2.2 2 1 0 2 2 2 1 Snapin/Pallidin AKNA PF12443.8 ORY05243.1 - 0.0086 16.7 0.8 0.0086 16.7 0.8 1.9 2 0 0 2 2 2 1 AT-hook-containing transcription factor bZIP_1 PF00170.21 ORY05243.1 - 0.014 15.5 6.0 0.014 15.5 6.0 2.4 2 1 1 3 3 3 0 bZIP transcription factor Tektin PF03148.14 ORY05243.1 - 0.014 14.2 2.4 0.014 14.2 2.4 1.8 2 0 0 2 2 2 0 Tektin family HMMR_N PF15905.5 ORY05243.1 - 0.016 14.7 9.4 0.019 14.4 9.4 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 ORY05243.1 - 0.016 15.4 1.8 0.016 15.4 1.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KfrA_N PF11740.8 ORY05243.1 - 0.019 15.6 5.9 0.031 15.0 5.9 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term CHD5 PF04420.14 ORY05243.1 - 0.019 14.8 0.2 0.019 14.8 0.2 1.6 2 0 0 2 2 2 0 CHD5-like protein WXG100 PF06013.12 ORY05243.1 - 0.024 14.8 0.8 0.62 10.3 0.4 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG PI3K_P85_iSH2 PF16454.5 ORY05243.1 - 0.025 14.2 9.4 0.28 10.8 9.4 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TssO PF17561.2 ORY05243.1 - 0.036 14.2 3.2 0.039 14.1 0.5 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO DivIC PF04977.15 ORY05243.1 - 0.046 13.5 4.4 0.046 13.5 4.4 2.1 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 ORY05243.1 - 0.047 14.1 4.6 0.047 14.1 4.6 2.2 2 0 0 2 2 2 0 Cell division protein ZapB ADIP PF11559.8 ORY05243.1 - 0.05 13.7 6.0 0.32 11.1 0.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 ORY05243.1 - 0.053 13.6 1.9 0.078 13.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) VPS11_C PF12451.8 ORY05243.1 - 0.056 13.7 0.6 0.15 12.4 0.6 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal UPF0242 PF06785.11 ORY05243.1 - 0.067 13.3 7.4 0.083 13.0 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 ORY05243.1 - 0.094 12.8 10.1 0.067 13.2 4.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4709 PF15821.5 ORY05243.1 - 0.12 12.6 6.3 1.2 9.4 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) DivIVA PF05103.13 ORY05243.1 - 0.19 11.8 9.0 0.06 13.4 1.9 2.0 2 0 0 2 2 2 0 DivIVA protein BLOC1_2 PF10046.9 ORY05243.1 - 0.21 11.9 8.3 0.81 10.0 2.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 ORY05243.1 - 0.21 12.0 6.0 0.51 10.8 2.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 ORY05243.1 - 0.22 11.1 2.2 0.26 10.8 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LPP PF04728.13 ORY05243.1 - 0.25 11.8 3.4 0.35 11.3 1.0 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper KIF1B PF12423.8 ORY05243.1 - 0.28 11.6 2.6 0.59 10.6 0.2 2.4 2 0 0 2 2 2 0 Kinesin protein 1B MtrG PF04210.13 ORY05243.1 - 0.35 10.7 3.0 17 5.3 0.0 2.7 2 2 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G FapA PF03961.13 ORY05243.1 - 0.39 9.3 6.2 0.45 9.1 6.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spore_III_AB PF09548.10 ORY05243.1 - 0.42 10.7 4.9 0.56 10.3 4.9 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Prominin PF05478.11 ORY05243.1 - 0.48 8.3 2.8 0.5 8.3 2.8 1.0 1 0 0 1 1 1 0 Prominin DUF4337 PF14235.6 ORY05243.1 - 0.49 10.5 5.6 0.83 9.8 5.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) UPF0449 PF15136.6 ORY05243.1 - 0.6 10.6 9.5 0.72 10.4 4.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF4407 PF14362.6 ORY05243.1 - 0.63 9.3 3.9 0.89 8.8 3.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MRPL52 PF18699.1 ORY05243.1 - 0.75 10.0 5.3 0.29 11.3 1.6 1.9 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Rho_Binding PF08912.11 ORY05243.1 - 0.91 10.4 15.0 1.5 9.7 5.7 2.3 2 0 0 2 2 2 0 Rho Binding Takusan PF04822.13 ORY05243.1 - 0.98 9.3 9.8 0.082 12.8 2.1 2.5 1 1 2 3 3 3 0 Takusan TMPIT PF07851.13 ORY05243.1 - 1.8 7.7 4.3 2.5 7.3 4.3 1.3 1 1 0 1 1 1 0 TMPIT-like protein DUF4164 PF13747.6 ORY05243.1 - 1.9 8.8 10.1 3.7 7.9 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) BST2 PF16716.5 ORY05243.1 - 2 9.1 8.9 0.23 12.0 2.8 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 EMP24_GP25L PF01105.24 ORY05243.1 - 2.6 7.9 9.6 5.4 6.9 2.2 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Val_tRNA-synt_C PF10458.9 ORY05243.1 - 3.7 7.9 10.1 0.78 10.1 4.6 2.6 2 2 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm YabA PF06156.13 ORY05243.1 - 4.4 8.0 9.8 1.9e+02 2.7 9.8 2.1 1 1 0 1 1 1 0 Initiation control protein YabA XhlA PF10779.9 ORY05243.1 - 4.6 7.5 7.2 1.6 9.0 0.6 2.7 2 2 0 2 2 2 0 Haemolysin XhlA DUF5320 PF17253.2 ORY05243.1 - 4.8 8.3 6.5 1.5 10.0 2.5 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 ORY05243.1 - 5.3 7.6 18.5 9.9 6.7 17.8 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 ORY05243.1 - 9.6 6.5 13.5 4.1 7.7 5.9 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Pro_isomerase PF00160.21 ORY05244.1 - 8.7e-56 188.6 0.0 1.1e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 ORY05244.1 - 0.092 12.4 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) HD_3 PF13023.6 ORY05245.1 - 8.5e-45 152.6 1.7 9.5e-45 152.5 1.7 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ORY05245.1 - 8.6e-13 48.4 1.2 1.1e-12 48.1 1.2 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 ORY05245.1 - 0.0015 18.8 0.8 0.0034 17.6 0.8 1.6 1 1 0 1 1 1 1 HD domain DUF3523 PF12037.8 ORY05245.1 - 0.011 15.2 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) RIC1 PF07064.13 ORY05246.1 - 1.9e-83 279.7 0.3 2.8e-83 279.2 0.3 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 ORY05246.1 - 9.7e-05 22.6 0.0 0.0012 19.1 0.0 2.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RGS PF00615.19 ORY05247.1 - 1.4e-08 35.0 0.2 9.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Spt5-NGN PF03439.13 ORY05248.1 - 2.2e-26 91.5 0.0 4.8e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 ORY05248.1 - 4.8e-20 70.8 24.2 3.2e-06 26.9 0.3 7.4 8 0 0 8 8 8 5 KOW motif Spt5_N PF11942.8 ORY05248.1 - 4.5e-19 69.3 10.8 4.5e-19 69.3 10.8 3.0 4 0 0 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 ORY05248.1 - 6.9e-07 29.7 45.3 0.017 15.7 38.0 3.4 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 ORY05248.1 - 0.011 16.0 0.3 0.058 13.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Nop14 PF04147.12 ORY05248.1 - 0.34 9.1 13.5 0.45 8.7 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family PIP5K PF01504.18 ORY05249.1 - 4.1e-102 341.1 0.5 6.9e-102 340.4 0.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MCU PF04678.13 ORY05251.1 - 1.8e-28 99.9 0.1 2.2e-28 99.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter FlxA PF14282.6 ORY05251.1 - 0.87 9.6 5.7 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 FlxA-like protein BTB PF00651.31 ORY05252.1 - 1.1e-18 67.4 4.3 1.5e-18 67.0 1.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 ORY05252.1 - 6e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 MATH domain dDENN PF03455.19 ORY05252.1 - 0.066 13.2 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 dDENN domain PIG-F PF06699.11 ORY05253.1 - 5.7e-41 140.6 6.1 6.9e-41 140.4 6.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F UPF0016 PF01169.19 ORY05253.1 - 0.0046 17.3 0.4 0.0046 17.3 0.4 2.5 3 0 0 3 3 3 1 Uncharacterized protein family UPF0016 Trp_Tyr_perm PF03222.13 ORY05253.1 - 0.018 14.1 2.4 0.027 13.5 2.4 1.3 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family DUF2530 PF10745.9 ORY05253.1 - 0.018 15.3 4.2 0.14 12.4 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Tetraspanin PF00335.20 ORY05253.1 - 0.021 14.5 0.9 0.037 13.7 0.9 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF373 PF04123.13 ORY05253.1 - 0.057 12.9 0.2 0.07 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TssN PF17555.2 ORY05253.1 - 0.094 12.1 1.1 0.16 11.4 1.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN ISK_Channel PF02060.15 ORY05253.1 - 0.11 12.2 0.1 0.4 10.4 0.2 1.8 2 0 0 2 2 2 0 Slow voltage-gated potassium channel TctB PF07331.11 ORY05253.1 - 0.2 12.0 11.9 0.84 9.9 6.3 2.4 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DHHC PF01529.20 ORY05253.1 - 0.93 9.6 2.6 1.2 9.2 1.7 1.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase PX PF00787.24 ORY05254.1 - 4.4e-23 81.4 1.4 6.2e-23 80.9 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY05254.1 - 2.6e-10 40.3 8.8 7.1e-05 22.5 1.0 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 ORY05254.1 - 0.00081 18.9 0.4 0.045 13.2 0.0 2.4 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein Baculo_PEP_C PF04513.12 ORY05254.1 - 0.036 14.1 1.6 0.68 10.0 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5320 PF17253.2 ORY05254.1 - 2.3 9.4 3.2 21 6.3 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) zf-HIT PF04438.16 ORY05255.1 - 2e-06 27.6 12.2 3.2e-06 26.9 12.2 1.3 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 ORY05255.1 - 1.7 6.4 6.0 2.5 5.8 6.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Rab3-GTPase_cat PF13890.6 ORY05257.1 - 1.1e-57 194.2 1.6 2.4e-57 193.1 1.6 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit Cupin_1 PF00190.22 ORY05258.1 - 3.6e-44 150.0 0.0 2.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ORY05258.1 - 2.7e-28 97.5 0.9 4e-13 48.9 0.1 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ORY05258.1 - 4e-11 43.0 0.3 6.7e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 ORY05258.1 - 4.2e-09 36.5 0.0 0.00033 20.8 0.0 2.5 2 0 0 2 2 2 2 Mif2/CENP-C like MannoseP_isomer PF01050.18 ORY05258.1 - 5.5e-06 26.3 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 ORY05258.1 - 1.3e-05 24.8 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_8 PF13621.6 ORY05258.1 - 0.00048 19.9 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 2 Cupin-like domain ARD PF03079.14 ORY05258.1 - 0.0021 18.3 0.2 2.5 8.3 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family GPI PF06560.11 ORY05258.1 - 0.017 14.4 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) FdtA PF05523.11 ORY05258.1 - 0.021 14.5 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 WxcM-like, C-terminal Cupin_6 PF12852.7 ORY05258.1 - 0.036 13.8 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Cupin Cupin_4 PF08007.12 ORY05258.1 - 0.076 12.5 0.1 0.79 9.1 0.1 2.0 2 0 0 2 2 2 0 Cupin superfamily protein DUF1971 PF09313.11 ORY05258.1 - 0.081 12.9 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) OPT PF03169.15 ORY05259.1 - 3.1e-08 32.7 0.5 3.5e-08 32.6 0.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TNFR_16_TM PF18422.1 ORY05259.1 - 0.042 13.8 5.6 0.13 12.2 1.3 2.2 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain OPT PF03169.15 ORY05260.1 - 6.9e-90 302.4 38.8 7.9e-90 302.2 38.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TAS2R PF05296.13 ORY05260.1 - 0.014 14.6 0.2 0.029 13.5 0.2 1.5 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) TMEM40 PF15817.5 ORY05260.1 - 0.028 14.2 1.2 0.51 10.1 0.2 2.7 2 0 0 2 2 2 0 Transmembrane protein 40 family DUF4191 PF13829.6 ORY05260.1 - 0.73 9.1 5.7 3 7.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Transket_pyr PF02779.24 ORY05261.1 - 2.6e-48 164.0 0.0 4e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORY05261.1 - 4.3e-48 162.9 0.0 2.2e-47 160.5 0.0 2.1 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORY05261.1 - 1.1e-40 139.5 0.1 6.4e-40 137.0 0.0 2.0 2 0 0 2 2 2 1 Dehydrogenase E1 component Amidohydro_1 PF01979.20 ORY05262.1 - 2.8e-71 240.6 0.0 3.5e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY05262.1 - 7.4e-11 42.2 0.0 3e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family FAD_binding_4 PF01565.23 ORY05262.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.25 ORY05310.1 - 6.3e-41 140.0 0.6 7.8e-41 139.7 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY05310.1 - 1.2e-32 113.3 0.1 1.5e-32 113.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY05310.1 - 1.6e-13 51.0 0.1 2.1e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY05310.1 - 4e-07 30.1 0.1 6.1e-07 29.5 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ORY05310.1 - 4.6e-06 26.2 0.0 1.4e-05 24.6 0.1 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.12 ORY05310.1 - 0.00048 19.4 0.2 0.0011 18.2 0.2 1.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY05310.1 - 0.0049 16.0 0.2 0.0082 15.3 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY05310.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 ORY05310.1 - 0.024 14.6 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase BAG PF02179.16 ORY05311.1 - 3.6e-09 36.9 0.4 7.4e-09 35.9 0.4 1.8 1 1 0 1 1 1 1 BAG domain DUF982 PF06169.12 ORY05311.1 - 0.056 13.5 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF982) baeRF_family10 PF18854.1 ORY05311.1 - 1.7 8.9 7.1 1.3 9.3 5.2 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 IQ PF00612.27 ORY05311.1 - 4 7.5 8.7 0.11 12.4 2.2 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif Chitin_bind_1 PF00187.19 ORY05312.1 - 2.4e-07 31.1 14.6 2.4e-07 31.1 14.6 2.0 2 0 0 2 2 2 1 Chitin recognition protein Yae1_N PF09811.9 ORY05313.1 - 1.3e-07 31.2 26.3 0.00037 20.1 1.9 4.1 2 1 2 4 4 4 4 Essential protein Yae1, N terminal Polysacc_deac_1 PF01522.21 ORY05314.1 - 2.9e-26 91.8 0.0 5.3e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ORY05314.1 - 5e-07 30.1 14.1 8.5e-07 29.4 14.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 ORY05314.1 - 1.3e-05 25.0 0.2 2.4e-05 24.1 0.2 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ORY05314.1 - 0.012 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 T3SS_needle_reg PF09025.10 ORY05314.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator Forkhead PF00250.18 ORY05315.1 - 8e-34 115.8 0.4 8.8e-34 115.6 0.4 1.0 1 0 0 1 1 1 1 Forkhead domain MFS_1 PF07690.16 ORY05316.1 - 7.9e-49 166.5 24.3 7.9e-49 166.5 24.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY05316.1 - 1e-09 37.8 22.7 2.5e-09 36.5 22.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY05316.1 - 3.7e-06 25.6 3.1 7.8e-06 24.6 3.1 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 ORY05316.1 - 0.00077 17.9 1.5 0.00077 17.9 1.5 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FPN1 PF06963.12 ORY05316.1 - 0.0013 17.4 2.0 0.0048 15.5 0.0 2.3 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Gly-zipper_Omp PF13488.6 ORY05316.1 - 0.075 13.0 2.6 0.2 11.7 0.1 2.5 2 0 0 2 2 2 0 Glycine zipper DUF4131 PF13567.6 ORY05316.1 - 0.34 10.5 0.0 0.34 10.5 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Transgly_assoc PF04226.13 ORY05316.1 - 3 8.2 15.1 9.9 6.5 0.0 4.1 3 1 0 3 3 3 0 Transglycosylase associated protein EF-hand_6 PF13405.6 ORY05317.1 - 8.5e-08 31.5 2.2 0.0035 17.2 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ORY05317.1 - 3.7e-07 29.2 2.8 0.0041 16.6 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 ORY05317.1 - 2e-06 27.0 4.8 0.0022 17.4 0.6 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ORY05317.1 - 4.1e-06 27.1 2.5 8.2e-06 26.2 2.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY05317.1 - 0.002 18.0 3.2 0.063 13.1 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair BC10 PF06726.12 ORY05318.1 - 1.3e-14 54.2 7.2 1.4e-14 54.1 7.2 1.0 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 ADK PF00406.22 ORY05319.1 - 1.6e-44 151.6 0.0 2.3e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY05319.1 - 9.8e-35 119.9 0.2 2.1e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY05319.1 - 2.2e-10 41.2 0.0 3.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY05319.1 - 8.3e-07 29.3 0.0 7.4e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 ORY05319.1 - 0.11 12.4 0.0 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase NAD_kinase PF01513.21 ORY05319.1 - 0.15 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Ribosomal_S13 PF00416.22 ORY05320.1 - 7.4e-24 84.6 0.5 1.5e-21 77.1 0.5 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORY05320.1 - 0.00012 21.0 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) CLASP_N PF12348.8 ORY05321.1 - 2.2e-13 50.3 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal MRP-L20 PF12824.7 ORY05321.1 - 0.018 15.2 2.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 DUF2465 PF10239.9 ORY05321.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) Forkhead PF00250.18 ORY05322.1 - 7.8e-34 115.8 0.1 1e-33 115.5 0.1 1.1 1 0 0 1 1 1 1 Forkhead domain TRAPPC-Trs85 PF12739.7 ORY05323.1 - 1.8e-112 376.3 0.0 2.6e-112 375.8 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 ORY05323.1 - 0.00065 19.2 3.0 0.068 12.6 0.3 2.4 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TRAPPC9-Trs120 PF08626.11 ORY05323.1 - 0.0069 13.8 0.0 0.01 13.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF1120 PF06551.12 ORY05323.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) TPR_2 PF07719.17 ORY05323.1 - 0.24 11.6 3.4 14 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 ORY05324.1 - 3.4e-32 110.7 0.8 6.2e-14 52.2 0.0 3.9 3 1 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 ORY05324.1 - 5.4e-24 82.4 0.0 0.00033 21.1 0.0 6.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 ORY05324.1 - 8.6e-11 41.1 0.2 0.011 16.0 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 ORY05324.1 - 2.8e-06 27.7 0.1 0.0067 16.9 0.1 3.8 4 1 0 4 4 4 2 HEAT-like repeat Arm PF00514.23 ORY05324.1 - 1.2e-05 25.2 0.0 0.0031 17.5 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat GIT_SHD PF08518.11 ORY05325.1 - 6.3e-24 83.3 7.7 1e-12 47.4 1.3 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ATG16 PF08614.11 ORY05325.1 - 0.0015 18.8 9.4 0.0015 18.8 9.4 4.5 5 1 1 6 6 6 2 Autophagy protein 16 (ATG16) GIT1_C PF12205.8 ORY05325.1 - 0.0053 16.9 1.8 0.0053 16.9 1.8 4.4 3 2 1 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term IBN_N PF03810.19 ORY05326.1 - 6.5e-19 67.6 0.2 2.7e-18 65.7 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORY05326.1 - 0.0086 16.1 0.2 1.8 8.6 0.1 3.4 3 0 0 3 3 3 1 Exportin 1-like protein Phytochelatin PF05023.14 ORY05327.1 - 1e-82 276.5 0.0 1.8e-82 275.7 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 ORY05327.1 - 0.011 16.3 0.1 0.12 13.0 0.0 2.5 2 1 0 2 2 2 0 Peptidase_C39 like family RICTOR_N PF14664.6 ORY05327.1 - 0.038 13.0 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term PAP2_C PF14360.6 ORY05328.1 - 8.3e-18 64.7 6.0 8.3e-18 64.7 6.0 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORY05328.1 - 3e-06 27.0 9.2 3e-06 27.0 9.2 1.9 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 ORY05328.1 - 3.3 7.4 18.5 1.8 8.2 14.3 2.3 2 1 0 2 2 2 0 PAP2 superfamily CAP_GLY PF01302.25 ORY05329.1 - 5.9e-26 90.3 0.3 6.4e-26 90.2 0.3 1.0 1 0 0 1 1 1 1 CAP-Gly domain cNMP_binding PF00027.29 ORY05330.1 - 1.6e-25 89.0 0.1 2.5e-12 46.7 0.0 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 ORY05330.1 - 1.1e-18 68.2 7.4 7.8e-17 62.1 7.1 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase PAP2 PF01569.21 ORY05331.1 - 1.1e-10 41.4 4.7 1.2e-10 41.2 4.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF202 PF02656.15 ORY05331.1 - 0.03 14.7 2.6 0.047 14.1 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF4131 PF13567.6 ORY05331.1 - 0.24 11.1 3.4 0.27 10.9 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) BUD22 PF09073.10 ORY05332.1 - 3.5e-57 194.7 53.2 3.2e-46 158.6 45.4 3.3 2 1 0 2 2 2 2 BUD22 Efg1 PF10153.9 ORY05332.1 - 0.01 16.2 10.1 0.01 16.2 10.1 3.2 3 1 0 3 3 3 0 rRNA-processing protein Efg1 ATP-cone PF03477.16 ORY05332.1 - 0.014 16.0 2.0 0.058 14.0 1.8 2.2 1 1 1 2 2 2 0 ATP cone domain UPF0172 PF03665.13 ORY05333.1 - 1.9e-52 178.1 0.0 2.2e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) tRNA_anti-codon PF01336.25 ORY05334.1 - 0.00016 21.6 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain P-mevalo_kinase PF04275.14 ORY05335.1 - 0.03 14.2 0.6 0.058 13.3 0.6 1.4 1 0 0 1 1 1 0 Phosphomevalonate kinase HMG_box PF00505.19 ORY05336.1 - 1.1e-19 70.6 1.3 1.1e-19 70.6 1.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY05336.1 - 5.9e-16 58.8 1.3 5.9e-16 58.8 1.3 2.0 2 0 0 2 2 2 1 HMG-box domain Laminin_II PF06009.12 ORY05336.1 - 0.0048 16.9 2.0 0.0048 16.9 2.0 1.7 2 0 0 2 2 2 1 Laminin Domain II HMG_box_5 PF14887.6 ORY05336.1 - 0.038 14.0 0.3 0.038 14.0 0.3 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 KIAA1430 PF13879.6 ORY05336.1 - 1.2 9.9 7.3 4.8 8.0 7.3 2.3 1 1 0 1 1 1 0 KIAA1430 homologue COX4 PF02936.14 ORY05336.1 - 1.3 9.0 5.5 0.23 11.5 0.9 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Vpu PF00558.19 ORY05336.1 - 1.7 8.5 7.6 0.2 11.5 1.0 2.4 1 1 1 2 2 2 0 Vpu protein Ribosomal_S3Ae PF01015.18 ORY05337.1 - 5.4e-94 313.5 1.4 6.7e-94 313.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 ORY05337.1 - 0.027 15.0 0.2 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 ORY05337.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NIF PF03031.18 ORY05338.1 - 2.6e-45 154.0 0.5 3.3e-45 153.6 0.5 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_47 PF01532.20 ORY05339.1 - 5.6e-96 322.2 0.9 6.3e-80 269.3 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 TAP42 PF04177.12 ORY05340.1 - 1e-92 310.7 16.4 1.2e-92 310.5 16.4 1.0 1 0 0 1 1 1 1 TAP42-like family Tox-ODYAM1 PF15642.6 ORY05340.1 - 3.4 6.5 9.3 4.3 6.2 8.7 1.4 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Forkhead PF00250.18 ORY05341.1 - 9.8e-38 128.3 0.2 1.8e-37 127.4 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 ORY05341.1 - 1e-11 45.0 0.1 2.2e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Ribosomal_S26e PF01283.19 ORY05342.1 - 2.7e-54 182.2 6.6 3.2e-54 181.9 6.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 ORY05342.1 - 0.071 13.7 2.6 0.8 10.3 1.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyco_transf_20 PF00982.21 ORY05343.1 - 2.2e-164 547.6 0.0 2.9e-164 547.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY05343.1 - 4.8e-61 205.9 0.0 6.8e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY05343.1 - 3.8e-12 46.5 0.0 0.00014 21.7 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 ORY05343.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF1724 PF08350.10 ORY05343.1 - 0.073 13.2 0.9 1.8 8.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1724) Ribosomal_L18A PF01775.17 ORY05344.1 - 1.7e-46 157.2 0.8 2.1e-46 156.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A RrnaAD PF00398.20 ORY05345.1 - 9.4e-49 165.8 0.1 1.1e-48 165.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ORY05345.1 - 0.0014 19.3 0.0 0.0032 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY05345.1 - 0.089 13.5 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain BORCS8 PF10167.9 ORY05346.1 - 4.6e-05 23.3 0.5 8.8e-05 22.4 0.2 1.6 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 Ribosomal_L28e PF01778.17 ORY05347.1 - 5.1e-35 120.7 0.4 7.3e-35 120.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family GDI PF00996.18 ORY05348.1 - 2.8e-63 214.0 0.2 1.9e-46 158.5 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Rer1 PF03248.13 ORY05349.1 - 1.6e-79 265.6 7.0 1.9e-79 265.4 7.0 1.0 1 0 0 1 1 1 1 Rer1 family WD40 PF00400.32 ORY05350.1 - 3.3e-40 135.3 15.5 1.4e-06 28.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY05350.1 - 3.9e-17 62.3 0.0 0.00031 21.0 0.1 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY05350.1 - 0.00038 20.4 0.0 0.17 11.7 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY05350.1 - 0.0017 17.7 0.0 0.03 13.7 0.0 2.6 2 1 2 4 4 4 2 WD40-like domain Nup160 PF11715.8 ORY05350.1 - 0.011 14.4 0.1 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORY05350.1 - 0.097 11.2 0.0 0.18 10.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ret2_MD PF18528.1 ORY05350.1 - 0.11 12.9 0.0 30 5.1 0.0 3.1 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain ThrE PF06738.12 ORY05351.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter 7tm_1 PF00001.21 ORY05352.1 - 0.25 10.6 13.2 0.38 10.0 13.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 ORY05352.1 - 5.4 7.2 8.4 0.33 11.1 0.8 2.8 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Peptidase_S10 PF00450.22 ORY05353.1 - 6.2e-123 411.3 0.4 7.6e-123 411.0 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 ORY05353.1 - 0.099 13.2 0.0 0.85 10.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3982 PF13138.6 ORY05354.1 - 0.036 13.8 1.4 0.099 12.4 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) IQ PF00612.27 ORY05358.1 - 1.6e-58 189.0 88.5 0.00066 19.3 0.1 23.8 23 0 0 23 23 23 21 IQ calmodulin-binding motif RasGAP PF00616.19 ORY05358.1 - 2.7e-56 190.6 1.1 2.7e-56 190.6 1.1 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY05358.1 - 4.3e-41 140.3 6.9 4.3e-41 140.3 6.9 4.0 4 0 0 4 4 4 1 RasGAP C-terminus CH PF00307.31 ORY05358.1 - 1.5e-17 63.7 1.4 7.1e-17 61.6 0.0 3.0 3 0 0 3 3 3 1 Calponin homology (CH) domain RUN PF02759.19 ORY05358.1 - 0.078 12.9 11.9 0.16 11.9 0.4 4.2 3 1 1 4 4 4 0 RUN domain Med13_C PF06333.12 ORY05358.1 - 0.12 11.7 0.1 0.63 9.2 0.0 2.3 2 1 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain YvfG PF09628.10 ORY05358.1 - 0.18 12.2 6.7 53 4.3 0.0 5.3 3 2 1 4 4 4 0 YvfG protein Herpes_UL51 PF04540.13 ORY05358.1 - 0.61 9.8 19.4 6.3 6.5 0.3 6.6 3 1 4 8 8 8 0 Herpesvirus UL51 protein Ribonuc_L-PSP PF01042.21 ORY05358.1 - 2.4 8.2 13.2 9.4 6.3 0.8 5.1 3 2 2 5 5 5 0 Endoribonuclease L-PSP HA2 PF04408.23 ORY05359.1 - 2.2e-26 92.2 0.0 5.2e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY05359.1 - 2.2e-21 76.0 0.0 6.4e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY05359.1 - 5.9e-11 42.7 0.0 1.6e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY05359.1 - 1.1e-09 38.3 0.1 2.4e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY05359.1 - 1.2e-06 28.8 0.1 3.5e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY05359.1 - 0.00058 20.2 0.1 0.0012 19.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY05359.1 - 0.0083 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ORY05359.1 - 0.03 13.9 0.1 0.08 12.6 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 ORY05359.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY05359.1 - 0.043 12.9 0.0 0.091 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 ORY05359.1 - 0.054 12.9 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 ORY05359.1 - 0.054 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORY05359.1 - 0.058 13.4 0.0 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 ORY05359.1 - 0.079 13.5 0.1 2.1 8.9 0.0 2.5 1 1 1 2 2 2 0 ABC transporter cobW PF02492.19 ORY05359.1 - 0.12 11.9 0.0 13 5.4 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 ORY05359.1 - 0.13 12.3 0.3 2.3 8.3 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY05359.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region SOG2 PF10428.9 ORY05360.1 - 8.6 5.4 10.3 11 5.0 10.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HLH PF00010.26 ORY05363.1 - 6.5e-15 54.8 0.6 1.2e-14 54.0 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SNAP PF14938.6 ORY05364.1 - 2.5e-30 105.9 12.8 3.1e-30 105.6 12.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 ORY05364.1 - 1.1e-06 28.3 0.7 1e-05 25.1 0.6 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 ORY05364.1 - 1.2e-05 25.5 6.6 0.076 13.3 6.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY05364.1 - 0.0002 21.3 14.6 0.054 13.7 1.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY05364.1 - 0.007 16.4 17.6 2.1 8.7 1.7 5.2 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY05364.1 - 0.018 15.8 6.4 40 5.4 0.5 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Tim44 PF04280.15 ORY05364.1 - 0.027 14.6 0.8 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 Tim44-like domain TOM20_plant PF06552.12 ORY05364.1 - 0.032 14.0 2.8 0.086 12.6 2.3 2.0 2 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_1 PF00515.28 ORY05364.1 - 0.041 13.7 14.7 2.2 8.3 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY05364.1 - 0.049 13.7 5.8 24 5.3 0.0 4.5 3 2 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 ORY05364.1 - 0.23 11.4 4.6 12 5.7 0.1 3.8 1 1 2 4 4 4 0 Region in Clathrin and VPS TPR_6 PF13174.6 ORY05364.1 - 0.48 11.2 11.7 5.4 7.9 3.0 4.8 2 1 2 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_9 PF00759.19 ORY05364.1 - 8.6 5.7 12.4 1.5 8.2 3.8 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 9 Gemin7 PF11095.8 ORY05365.1 - 3.2e-16 59.0 0.0 3.5e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Dzip-like_N PF13815.6 ORY05366.1 - 0.00079 19.4 0.4 0.00079 19.4 0.4 3.0 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF4407 PF14362.6 ORY05366.1 - 0.019 14.4 10.5 0.37 10.1 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 ORY05366.1 - 0.022 14.7 6.2 0.022 14.7 6.2 3.8 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding betaPIX_CC PF16523.5 ORY05366.1 - 0.057 13.3 1.0 0.057 13.3 1.0 3.2 3 1 0 3 3 3 0 betaPIX coiled coil PKcGMP_CC PF16808.5 ORY05366.1 - 0.13 12.2 7.5 1.5 8.7 1.8 3.3 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 ORY05366.1 - 0.37 9.8 17.3 0.64 9.0 16.3 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 ORY05366.1 - 0.49 9.9 22.4 0.16 11.6 15.1 2.1 2 0 0 2 2 2 0 TMCO5 family MscS_porin PF12795.7 ORY05366.1 - 0.9 9.0 21.4 0.035 13.7 12.9 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain OmpH PF03938.14 ORY05366.1 - 2.3 8.6 16.7 0.15 12.4 7.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) KASH_CCD PF14662.6 ORY05366.1 - 3.3 7.5 26.2 0.37 10.6 17.1 2.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH PHM7_cyt PF14703.6 ORY05366.1 - 3.3 7.9 7.4 10 6.3 6.9 2.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF724 PF05266.14 ORY05366.1 - 8.3 6.2 18.0 0.59 9.9 3.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Glyco_transf_22 PF03901.17 ORY05367.1 - 3.1e-86 290.2 29.5 4e-82 276.7 24.0 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 ORY05367.1 - 0.0039 17.4 12.8 0.0039 17.4 12.8 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NADH_u_ox_C PF12853.7 ORY05367.1 - 0.11 12.5 0.6 0.69 9.9 0.1 2.3 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit HPP PF04982.13 ORY05368.1 - 2.7e-44 150.3 6.1 2.7e-44 150.3 6.1 1.4 2 0 0 2 2 2 1 HPP family Phage_holin_3_3 PF16083.5 ORY05368.1 - 0.06 13.5 2.1 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III ArAE_2_N PF10337.9 ORY05368.1 - 0.094 11.7 3.5 0.2 10.7 3.5 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2070 PF09843.9 ORY05368.1 - 5.3 5.2 8.5 8 4.6 8.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EMP24_GP25L PF01105.24 ORY05369.1 - 2.9e-48 164.2 0.2 3.4e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Orf78 PF06024.12 ORY05369.1 - 0.012 16.0 0.1 0.045 14.0 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) TMEM132D_C PF15706.5 ORY05369.1 - 0.065 13.0 0.3 0.23 11.3 0.0 2.1 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term APH PF01636.23 ORY05370.1 - 1.3e-14 54.8 1.0 9.5e-14 51.9 0.9 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family PX PF00787.24 ORY05408.1 - 9.9e-19 67.4 0.1 2.3e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 PX domain HTH_40 PF14493.6 ORY05408.1 - 0.073 13.5 1.7 0.19 12.2 0.2 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Response_reg PF00072.24 ORY05409.1 - 9.9e-21 74.0 0.0 1.1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF934 PF06073.12 ORY05409.1 - 0.0055 16.6 0.0 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF934) HisKA PF00512.25 ORY05410.1 - 4.1e-09 36.3 0.6 1.6e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 ORY05410.1 - 1.3e-08 35.0 0.0 5.6e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain CHASE PF03924.13 ORY05410.1 - 5.4e-08 33.0 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 CHASE domain PAS PF00989.25 ORY05410.1 - 0.0014 18.7 0.0 0.052 13.5 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ORY05410.1 - 0.002 18.4 0.1 0.0079 16.4 0.0 2.1 2 0 0 2 2 2 1 PAS domain HATPase_c PF02518.26 ORY05410.1 - 0.0059 17.1 0.1 0.25 11.8 0.0 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ORY05410.1 - 0.019 15.0 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain DUF2393 PF09624.10 ORY05410.1 - 0.11 12.5 2.6 0.23 11.4 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF1356 PF07092.12 ORY05410.1 - 0.24 10.6 2.8 0.2 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) zf-H2C2_2 PF13465.6 ORY05411.1 - 9.1e-17 60.7 20.6 7.5e-06 26.1 0.2 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY05411.1 - 1.8e-12 47.0 25.3 3.1e-05 24.2 0.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY05411.1 - 9.8e-07 29.1 23.5 0.023 15.5 0.4 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORY05411.1 - 7.7e-05 23.2 2.7 2.9 8.6 0.0 3.1 1 1 2 3 3 3 3 FOXP coiled-coil domain zf-TRAF PF02176.18 ORY05411.1 - 0.001 19.7 2.6 0.001 19.7 2.6 2.7 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 ORY05411.1 - 0.0011 19.2 3.0 0.065 13.5 2.5 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 ORY05411.1 - 0.13 12.7 8.4 19 5.8 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type EAF PF09816.9 ORY05412.1 - 1.3e-19 70.4 0.6 2.8e-19 69.4 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor PI3K_1B_p101 PF10486.9 ORY05412.1 - 0.018 12.9 9.4 0.024 12.5 9.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Secretin_N_2 PF07655.13 ORY05412.1 - 2.1 9.0 21.1 5.3 7.7 21.1 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Arrestin_C PF02752.22 ORY05413.1 - 1.9e-10 41.3 0.6 3.9e-10 40.3 0.2 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY05413.1 - 4.6e-09 36.5 0.0 7.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY05413.1 - 0.00066 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Cyclin_N PF00134.23 ORY05414.1 - 1.6e-07 31.1 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY05414.1 - 5.7e-07 30.0 0.0 7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin Tom37 PF10568.9 ORY05414.1 - 0.024 14.9 0.1 0.044 14.1 0.0 1.5 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Med16 PF11635.8 ORY05416.1 - 3.5e-19 68.2 3.2 1.8e-13 49.4 0.7 2.2 2 1 0 2 2 2 2 Mediator complex subunit 16 VWA_3 PF13768.6 ORY05416.1 - 0.058 13.3 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain CCDC-167 PF15188.6 ORY05416.1 - 0.085 13.2 1.9 0.29 11.5 1.8 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Kinesin PF00225.23 ORY05417.1 - 4.2e-103 344.8 0.4 4.7e-103 344.6 0.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY05417.1 - 1.3e-17 64.1 0.1 3.6e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding FF PF01846.19 ORY05418.1 - 1.3e-43 146.9 19.5 2.8e-12 46.6 0.1 6.2 6 0 0 6 6 6 5 FF domain WW PF00397.26 ORY05418.1 - 3e-28 97.6 30.9 4.9e-10 39.3 2.9 4.4 4 0 0 4 4 4 3 WW domain RhoGAP-FF1 PF16512.5 ORY05418.1 - 1.5e-05 25.5 15.4 0.92 10.2 0.0 5.0 4 0 0 4 4 4 3 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 ORY05418.1 - 0.3 11.4 16.9 2.6 8.3 2.1 4.5 3 1 1 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain DASH_Duo1 PF08651.10 ORY05419.1 - 9e-18 63.8 3.2 1.5e-17 63.1 3.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 WavE PF07507.11 ORY05419.1 - 0.011 15.0 1.2 0.014 14.6 1.2 1.2 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis GCD14 PF08704.10 ORY05419.1 - 0.014 15.1 4.3 0.044 13.5 3.4 1.8 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit LRRC37AB_C PF14914.6 ORY05419.1 - 0.43 10.5 5.9 0.75 9.7 5.9 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain ALMT PF11744.8 ORY05419.1 - 7.4 5.3 9.3 9.2 5.0 9.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SIL1 PF16782.5 ORY05420.1 - 2.6e-18 66.3 0.1 3.5e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Fes1 PF08609.10 ORY05420.1 - 0.017 16.0 1.6 0.034 15.0 0.3 2.3 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 Acyltransferase PF01553.21 ORY05421.1 - 1.4e-20 73.3 0.0 2.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY05421.1 - 5.3e-12 45.7 1.3 1e-11 44.8 1.3 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus ABC_export PF16962.5 ORY05421.1 - 0.0081 14.7 0.3 0.012 14.1 0.3 1.2 1 0 0 1 1 1 1 Putative ABC exporter LRR_6 PF13516.6 ORY05422.1 - 1.6e-19 68.2 9.9 0.00034 20.4 0.0 8.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 ORY05422.1 - 1.7e-09 37.8 7.2 0.031 14.7 0.0 5.6 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY05422.1 - 1.2e-07 31.4 5.9 0.57 10.0 0.0 6.2 6 2 0 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 ORY05422.1 - 1.2e-05 25.2 2.8 28 5.8 0.0 6.8 9 0 0 9 9 9 0 Leucine Rich Repeat DUF5089 PF17002.5 ORY05422.1 - 0.0015 18.5 7.9 0.0031 17.4 7.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) LRR_9 PF14580.6 ORY05422.1 - 0.035 13.6 0.1 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeat Astro_capsid_p PF12226.8 ORY05422.1 - 1.1 8.3 8.3 1.6 7.8 8.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPL5 PF18168.1 ORY05422.1 - 1.3 8.2 4.9 4.9 6.3 2.5 2.2 2 0 0 2 2 2 0 Prim-pol family 5 DUF4746 PF15928.5 ORY05422.1 - 3.4 7.0 9.8 4.9 6.5 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) V_ATPase_I PF01496.19 ORY05422.1 - 6.9 4.5 5.0 9.2 4.0 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aa_trans PF01490.18 ORY05423.1 - 1.1e-65 221.9 35.7 1.3e-65 221.8 35.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY05423.1 - 2.5e-10 39.8 23.6 2.5e-10 39.8 23.6 2.4 1 1 1 2 2 2 1 Amino acid permease SLATT_1 PF18181.1 ORY05423.1 - 0.23 11.4 7.4 2.5 8.0 0.1 3.4 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 MerC PF03203.14 ORY05423.1 - 0.76 10.3 21.5 1.4 9.4 1.9 4.2 3 1 0 4 4 4 0 MerC mercury resistance protein DUF4231 PF14015.6 ORY05423.1 - 6 7.4 16.8 2.7 8.5 0.3 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) PLDc_2 PF13091.6 ORY05424.1 - 4.4e-15 55.7 0.0 1.6e-07 31.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PX PF00787.24 ORY05424.1 - 1.9e-11 44.0 0.6 5.7e-11 42.4 0.6 1.9 1 0 0 1 1 1 1 PX domain PLDc PF00614.22 ORY05424.1 - 2.9e-11 43.1 1.3 3.5e-05 23.8 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PH PF00169.29 ORY05424.1 - 5e-05 23.8 0.1 0.00012 22.5 0.1 1.7 1 0 0 1 1 1 1 PH domain Aim19 PF10315.9 ORY05425.1 - 2.1e-28 98.9 1.8 2.5e-28 98.7 1.8 1.0 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Tmemb_14 PF03647.13 ORY05425.1 - 0.0074 17.0 0.2 0.01 16.5 0.2 1.3 1 1 0 1 1 1 1 Transmembrane proteins 14C DUF202 PF02656.15 ORY05426.1 - 9.5e-13 48.4 1.9 9.5e-13 48.4 1.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.9 ORY05426.1 - 0.11 11.2 2.2 0.054 12.3 0.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) VTC PF09359.10 ORY05427.1 - 3.2e-100 335.1 0.6 3.2e-100 335.1 0.6 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 ORY05427.1 - 6.1e-15 55.4 1.4 1.2e-14 54.5 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY05427.1 - 9.9e-15 55.3 27.4 2.3e-07 31.1 0.9 4.3 2 1 2 4 4 4 4 SPX domain LXG PF04740.12 ORY05427.1 - 0.051 13.3 3.0 0.056 13.2 0.1 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Tropomyosin PF00261.20 ORY05427.1 - 0.079 12.3 7.3 0.11 11.8 2.9 2.2 2 0 0 2 2 2 0 Tropomyosin XhlA PF10779.9 ORY05427.1 - 0.2 11.9 3.1 3.8 7.8 0.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA TMF_DNA_bd PF12329.8 ORY05427.1 - 0.51 10.4 5.0 1 9.4 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 ORY05427.1 - 6.9 6.8 10.5 4.1 7.5 2.9 2.3 2 0 0 2 2 2 0 Tropomyosin like Ribosomal_L31e PF01198.19 ORY05428.1 - 2.7e-39 133.2 2.7 3.4e-39 133.0 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CLTH PF10607.9 ORY05429.1 - 4.3e-34 117.5 0.0 1.4e-33 115.9 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 ORY05429.1 - 2.7e-25 88.8 0.4 4.3e-25 88.1 0.4 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 ORY05429.1 - 2.1e-08 33.8 0.1 5.9e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 LisH Mid1 PF12929.7 ORY05430.1 - 1.1e-55 189.6 8.8 5.4e-54 184.0 8.8 2.2 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 ORY05430.1 - 0.00069 20.2 4.2 0.045 14.4 0.3 2.4 2 0 0 2 2 2 2 Fz domain ubiquitin PF00240.23 ORY05431.1 - 2e-06 27.5 0.1 3.4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 ORY05431.1 - 0.025 15.1 1.0 0.032 14.8 0.0 1.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY05431.1 - 0.027 14.5 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like S4 PF01479.25 ORY05431.1 - 0.056 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 S4 domain PhoLip_ATPase_C PF16212.5 ORY05432.1 - 5.8e-62 209.7 22.9 5.8e-62 209.7 22.9 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY05432.1 - 3e-15 55.6 5.5 3e-15 55.6 5.5 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY05432.1 - 3e-12 46.5 0.0 3.6e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY05432.1 - 1.8e-09 37.4 0.2 1.8e-09 37.4 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY05432.1 - 1.6e-08 35.1 0.2 0.0014 19.0 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY05432.1 - 0.00078 19.3 0.4 0.0076 16.0 0.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.6 ORY05432.1 - 0.14 12.3 0.1 1e+02 3.1 0.0 3.4 3 0 0 3 3 3 0 Papain fold toxin 2 PLA2G12 PF06951.11 ORY05433.1 - 0.0046 16.9 8.7 0.0053 16.7 8.2 1.4 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Spc29 PF17082.5 ORY05434.1 - 0.0018 18.2 4.2 0.0022 17.9 4.2 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 ALIX_LYPXL_bnd PF13949.6 ORY05434.1 - 0.0038 16.6 7.6 0.0044 16.4 7.6 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Spc7 PF08317.11 ORY05434.1 - 0.039 12.8 9.9 0.052 12.4 9.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tweety PF04906.13 ORY05434.1 - 0.046 12.4 0.7 0.053 12.2 0.7 1.3 1 0 0 1 1 1 0 Tweety CENP-Q PF13094.6 ORY05434.1 - 0.087 13.0 11.0 0.15 12.2 11.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec20 PF03908.13 ORY05434.1 - 0.13 12.2 3.6 0.11 12.4 1.5 1.9 1 1 1 2 2 2 0 Sec20 V_ATPase_I PF01496.19 ORY05434.1 - 0.16 9.8 4.0 0.17 9.8 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 ORY05434.1 - 0.21 11.4 16.7 0.27 11.0 16.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CorA PF01544.18 ORY05434.1 - 0.21 10.9 3.0 0.3 10.4 3.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PCRF PF03462.18 ORY05434.1 - 0.29 11.0 6.6 0.39 10.5 6.6 1.2 1 0 0 1 1 1 0 PCRF domain UPF0242 PF06785.11 ORY05434.1 - 0.49 10.5 11.4 0.6 10.2 11.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 ORY05434.1 - 0.5 9.6 11.6 0.84 8.9 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2277 PF10041.9 ORY05434.1 - 0.53 10.6 6.0 0.51 10.7 4.2 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) LMBR1 PF04791.16 ORY05434.1 - 1.2 7.9 5.2 1.3 7.8 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Arteri_nsp7a PF16749.5 ORY05434.1 - 1.7 8.8 6.7 1.3 9.2 2.7 2.3 1 1 1 2 2 2 0 Arterivirus nonstructural protein 7 alpha ZapB PF06005.12 ORY05434.1 - 9.4 6.8 19.6 2.1 8.8 13.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Glyco_transf_20 PF00982.21 ORY05435.1 - 3.8e-196 652.4 0.0 4.7e-196 652.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY05435.1 - 6.6e-57 192.3 0.0 1e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY05435.1 - 0.00011 22.0 0.1 0.037 13.8 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 ORY05435.1 - 0.13 11.8 0.2 1.3 8.6 0.2 2.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 Trm5_N PF18093.1 ORY05435.1 - 0.14 12.0 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain Bclx_interact PF08945.10 ORY05435.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain GCV_H PF01597.19 ORY05436.1 - 7.2e-44 148.6 0.4 8.4e-44 148.4 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein FTR_C PF02741.15 ORY05436.1 - 0.0025 17.8 0.8 0.017 15.1 0.1 2.0 1 1 1 2 2 2 1 FTR, proximal lobe GatB_N PF02934.15 ORY05437.1 - 1.3e-101 339.6 0.0 1.7e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ORY05437.1 - 1.2e-38 132.3 0.0 2e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 GatB domain PolyA_pol PF01743.20 ORY05438.1 - 1.4e-15 57.8 0.2 7e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ORY05438.1 - 4.8e-08 32.6 0.1 1.3e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A E1-E2_ATPase PF00122.20 ORY05439.1 - 4.6e-44 150.1 1.4 1.2e-43 148.8 1.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY05439.1 - 7.6e-41 139.8 3.8 7.6e-41 139.8 3.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY05439.1 - 1.1e-22 79.9 0.0 2.1e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY05439.1 - 1.2e-21 78.0 0.1 4.2e-14 53.3 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY05439.1 - 4.7e-11 42.2 1.5 1.8e-10 40.3 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY05439.1 - 1e-06 28.7 2.0 2.1e-06 27.6 0.5 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY05439.1 - 0.0019 18.6 0.0 0.026 14.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ORY05440.1 - 3e-69 233.3 0.0 3.6e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05440.1 - 2e-35 122.3 0.0 2.8e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY05440.1 - 0.00055 19.4 0.2 0.00095 18.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY05440.1 - 0.0019 17.2 0.2 0.003 16.6 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY05440.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY05440.1 - 0.017 15.0 0.3 0.15 12.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1198 PF06711.11 ORY05440.1 - 0.09 12.8 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) zf-Tim10_DDP PF02953.15 ORY05441.1 - 0.26 10.9 4.6 6.2 6.5 1.9 2.5 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Plasmodium_Vir PF05795.11 ORY05441.1 - 0.4 10.0 4.0 0.66 9.3 4.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_M3 PF01432.20 ORY05442.1 - 2.4e-138 462.3 0.0 3e-138 461.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 ORY05442.1 - 0.1 12.2 0.4 0.17 11.5 0.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like HIG_1_N PF04588.13 ORY05443.1 - 9.5e-10 38.6 2.0 9.5e-10 38.6 2.0 2.5 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Ubie_methyltran PF01209.18 ORY05444.1 - 7.1e-86 287.3 0.0 9.1e-86 287.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY05444.1 - 3.9e-17 62.7 0.0 8.3e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY05444.1 - 6.8e-17 61.9 0.0 1.5e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY05444.1 - 1.4e-14 54.1 0.0 3.8e-14 52.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY05444.1 - 6.3e-13 49.3 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY05444.1 - 9.9e-10 38.5 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY05444.1 - 0.00091 18.8 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 ORY05444.1 - 0.0039 17.1 0.0 0.044 13.6 0.0 2.3 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_5 PF01795.19 ORY05444.1 - 0.027 14.0 0.0 4.3 6.7 0.0 2.8 2 1 1 3 3 3 0 MraW methylase family Methyltransf_28 PF02636.17 ORY05444.1 - 0.043 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 ORY05444.1 - 0.16 11.0 0.0 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase Acid_PPase PF12689.7 ORY05445.1 - 1.3e-52 178.1 0.0 1.6e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 ORY05445.1 - 0.12 12.1 0.4 1.2 8.9 0.4 2.2 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase NLPC_P60 PF00877.19 ORY05445.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 NlpC/P60 family 4F5 PF04419.14 ORY05446.1 - 1.8e-09 38.3 10.5 1.8e-09 38.3 10.5 2.2 2 0 0 2 2 2 1 4F5 protein family EMC3_TMCO1 PF01956.16 ORY05446.1 - 5 6.8 8.0 5.3 6.8 8.0 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Sybindin PF04099.12 ORY05447.1 - 2.3e-53 180.0 0.1 2.6e-53 179.8 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY05447.1 - 2.5e-08 34.1 0.0 2.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sad1_UNC PF07738.13 ORY05448.1 - 2.6e-31 108.4 0.0 4.3e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2533 PF10752.9 ORY05448.1 - 0.045 14.2 2.3 0.19 12.2 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2533) COX4 PF02936.14 ORY05449.1 - 1.6e-39 135.1 0.4 2.6e-38 131.1 0.4 1.8 1 1 1 2 2 2 2 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.10 ORY05449.1 - 0.039 14.0 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative addiction module component DUF2034 PF10356.9 ORY05450.1 - 5.2e-18 65.1 0.1 2.4e-08 33.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 ORY05450.1 - 3.1e-12 46.5 0.0 3.3e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Restriction endonuclease DASH_Spc19 PF08287.11 ORY05451.1 - 6.6e-14 52.1 21.8 6.6e-14 52.1 21.8 3.1 1 1 1 2 2 2 1 Spc19 ABC_tran_CTD PF16326.5 ORY05451.1 - 0.0085 16.3 3.0 0.0085 16.3 3.0 4.1 4 1 1 5 5 5 1 ABC transporter C-terminal domain DUF4407 PF14362.6 ORY05451.1 - 0.076 12.4 14.4 0.67 9.3 8.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 ORY05451.1 - 0.7 7.7 15.7 1.3 6.8 15.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 ORY05451.1 - 1.2 7.7 23.9 1.5 7.3 10.5 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 ORY05451.1 - 4 7.8 26.0 4.7 7.6 14.6 3.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Rotamase PF00639.21 ORY05451.1 - 8 7.5 9.3 4.1 8.4 0.6 3.4 1 1 2 3 3 3 0 PPIC-type PPIASE domain FUSC PF04632.12 ORY05451.1 - 8 4.9 9.9 2.4 6.6 6.5 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF2203 PF09969.9 ORY05451.1 - 8.8 7.1 16.0 1.7 9.4 2.7 3.5 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) ATE_C PF04377.15 ORY05452.1 - 9.9e-51 171.9 1.2 9.9e-51 171.9 1.2 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ORY05452.1 - 8.3e-25 87.0 8.1 2.4e-24 85.5 8.1 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus LSM PF01423.22 ORY05454.1 - 5.4e-16 58.0 0.5 6.5e-16 57.8 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY05454.1 - 0.00014 21.9 0.1 0.00017 21.6 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain KH_1 PF00013.29 ORY05455.1 - 1.3e-20 73.0 4.7 2.4e-08 33.7 0.0 5.6 6 0 0 6 6 6 5 KH domain Beta-lactamase PF00144.24 ORY05456.1 - 5.3e-58 196.8 0.0 6.7e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase SH3_19 PF18597.1 ORY05456.1 - 0.011 15.5 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain Beta-lactamase2 PF13354.6 ORY05456.1 - 0.029 14.0 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family CK2S PF15011.6 ORY05457.1 - 1.2e-07 31.7 8.6 4.1e-07 30.0 8.6 1.8 1 1 0 1 1 1 1 Casein Kinase 2 substrate Glyco_hydro_49N PF17433.2 ORY05457.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain BLM10_N PF16547.5 ORY05457.1 - 0.1 12.9 0.2 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal Cortex-I_coil PF09304.10 ORY05457.1 - 6.4 7.0 8.0 1.7 8.9 1.4 2.6 2 2 0 2 2 2 0 Cortexillin I, coiled coil Spc24 PF08286.11 ORY05457.1 - 7 7.0 8.9 2 8.7 4.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 dCMP_cyt_deam_1 PF00383.23 ORY05458.1 - 2.5e-15 56.2 0.0 3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ORY05458.1 - 1e-11 45.2 0.3 1.8e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ORY05458.1 - 0.15 11.7 0.5 3.3 7.3 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Lipase_GDSL_2 PF13472.6 ORY05459.1 - 2.2e-20 73.8 0.0 4.4e-20 72.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY05459.1 - 6.7e-20 71.9 0.0 8.9e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase E1-E2_ATPase PF00122.20 ORY05460.1 - 1.6e-44 151.6 3.8 1.6e-44 151.6 3.8 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY05460.1 - 4.9e-42 143.7 3.0 4.9e-42 143.7 3.0 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY05460.1 - 5.7e-22 79.0 0.2 2.1e-11 44.5 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY05460.1 - 2.8e-18 65.8 0.0 6.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY05460.1 - 4.8e-13 48.6 0.7 2.4e-12 46.3 0.0 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY05460.1 - 4.4e-06 26.6 0.8 1.2e-05 25.3 0.8 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY05460.1 - 0.0031 17.9 0.0 0.052 14.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY05461.1 - 1.6e-44 151.6 3.8 1.6e-44 151.6 3.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY05461.1 - 2.1e-42 144.9 3.2 2.1e-42 144.9 3.2 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY05461.1 - 2.8e-22 80.1 0.5 2e-11 44.6 0.0 3.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY05461.1 - 2.6e-18 65.9 0.0 6.1e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY05461.1 - 2.2e-13 49.7 0.9 7.7e-13 47.9 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY05461.1 - 5e-06 26.4 0.8 1.2e-05 25.3 0.8 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY05461.1 - 0.0053 17.2 0.0 0.094 13.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY05462.1 - 1.4e-43 148.5 4.3 2.4e-43 147.8 1.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY05462.1 - 1.5e-43 148.7 2.4 1.5e-43 148.7 2.4 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY05462.1 - 6.6e-22 78.8 0.4 6.7e-11 42.9 0.0 3.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY05462.1 - 2.6e-18 65.9 0.0 6.2e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY05462.1 - 5e-12 45.3 0.9 1.5e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY05462.1 - 4.7e-06 26.5 0.8 1.2e-05 25.2 0.8 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY05462.1 - 0.0056 17.1 0.0 0.12 12.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3262 PF11660.8 ORY05462.1 - 0.076 13.4 2.3 4.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) DUF2157 PF09925.9 ORY05462.1 - 0.21 11.4 6.7 1.3 8.8 1.3 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Asn_synthase PF00733.21 ORY05463.1 - 8.6e-93 311.8 0.4 1.6e-52 179.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY05463.1 - 4.3e-38 130.0 0.0 7.6e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY05463.1 - 9.8e-33 113.2 0.0 2e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY05463.1 - 1.3e-07 31.4 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORY05463.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase ECH_1 PF00378.20 ORY05464.1 - 5.3e-41 140.6 0.0 6.3e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY05464.1 - 2.3e-13 50.4 0.0 2.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 ORY05464.1 - 0.00021 20.1 0.0 0.00031 19.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain bZIP_1 PF00170.21 ORY05465.1 - 4.6e-06 26.6 13.9 8.3e-05 22.6 14.2 2.4 1 1 1 2 2 2 1 bZIP transcription factor Zwint PF15556.6 ORY05465.1 - 0.0011 18.6 3.2 0.0015 18.1 3.2 1.1 1 0 0 1 1 1 1 ZW10 interactor Snapin_Pallidin PF14712.6 ORY05465.1 - 0.0012 19.2 2.0 0.0025 18.2 1.5 1.8 2 0 0 2 2 2 1 Snapin/Pallidin DUF3425 PF11905.8 ORY05465.1 - 0.012 15.5 0.0 0.045 13.7 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) TSKS PF15358.6 ORY05465.1 - 0.032 12.6 0.3 0.045 12.1 0.3 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate CC2D2AN-C2 PF15625.6 ORY05465.1 - 0.057 13.2 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Phlebovirus_NSM PF07246.11 ORY05465.1 - 0.093 12.1 0.8 0.14 11.5 0.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M bZIP_Maf PF03131.17 ORY05465.1 - 0.82 10.2 8.8 1.4 9.5 8.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY05465.1 - 6.8 6.9 15.4 4.7 7.4 6.7 2.9 1 1 1 2 2 2 0 Basic region leucine zipper G-alpha PF00503.20 ORY05466.1 - 9.2e-116 386.9 5.8 1.1e-115 386.6 5.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY05466.1 - 4.6e-15 55.5 2.9 1.4e-10 40.9 0.2 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY05466.1 - 0.00025 20.5 6.7 0.0009 18.7 0.3 2.9 2 2 1 3 3 3 1 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 ORY05466.1 - 0.0018 18.0 0.2 0.0062 16.3 0.1 1.9 2 0 0 2 2 2 1 CHC2 zinc finger AAA_28 PF13521.6 ORY05466.1 - 0.0078 16.5 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 ORY05466.1 - 0.0098 16.1 0.3 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY05466.1 - 0.011 15.8 0.0 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY05466.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KIND PF16474.5 ORY05466.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain DAP3 PF10236.9 ORY05466.1 - 0.15 11.2 0.5 0.28 10.3 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PPR_2 PF13041.6 ORY05467.1 - 9.5e-48 160.2 4.2 2.1e-11 43.8 0.2 9.5 5 1 5 10 10 10 8 PPR repeat family PPR PF01535.20 ORY05467.1 - 7.9e-34 113.5 2.6 8.3e-05 22.6 0.0 11.0 11 0 0 11 11 11 8 PPR repeat PPR_3 PF13812.6 ORY05467.1 - 4.3e-32 110.0 1.7 7.7e-06 25.9 0.0 8.4 6 3 4 10 10 10 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY05467.1 - 2.6e-19 69.4 0.0 0.00012 21.5 0.0 5.4 1 1 5 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY05467.1 - 1.3e-12 47.2 3.6 1.4 8.7 0.0 8.6 10 0 0 10 10 10 4 PPR repeat TPR_14 PF13428.6 ORY05467.1 - 0.00012 22.6 0.2 55 5.0 0.0 6.2 6 3 2 8 8 8 0 Tetratricopeptide repeat DUF3067 PF11267.8 ORY05467.1 - 0.0081 16.7 0.0 0.028 15.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) ANAPC3 PF12895.7 ORY05467.1 - 0.32 11.3 2.1 8 6.8 0.1 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PAS_3 PF08447.12 ORY05468.1 - 6.6e-16 58.4 0.0 1.5e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ORY05468.1 - 1.3e-11 44.5 0.0 4.6e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY05468.1 - 1.3e-06 28.6 0.0 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 ORY05468.1 - 0.00016 21.8 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORY05468.1 - 0.00017 21.8 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold TCO89 PF10452.9 ORY05469.1 - 1.1e-06 28.0 0.3 1.8e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 TORC1 subunit TCO89 SPRY PF00622.28 ORY05510.1 - 1.2e-22 80.2 0.1 2e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Peptidase_C2 PF00648.21 ORY05511.1 - 8.9e-43 146.4 0.1 2e-42 145.2 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 ORY05511.1 - 3.3e-18 66.3 6.2 7e-06 26.4 0.1 5.7 4 2 0 4 4 4 3 Calpain large subunit, domain III MIT PF04212.18 ORY05511.1 - 1.2e-13 50.8 12.8 5.4e-10 39.2 1.8 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Pertussis_S2S3 PF02918.15 ORY05511.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain TPR_2 PF07719.17 ORY05511.1 - 3 8.2 4.5 7.8 6.9 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Inhibitor_I24 PF10465.9 ORY05513.1 - 0.052 13.5 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 PinA peptidase inhibitor MIS13 PF08202.11 ORY05514.1 - 0.043 13.1 0.1 0.06 12.6 0.1 1.3 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Apolipoprotein PF01442.18 ORY05514.1 - 0.047 13.6 0.1 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain BORCS6 PF10157.9 ORY05514.1 - 0.05 13.8 0.1 0.07 13.4 0.1 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Baculo_PEP_C PF04513.12 ORY05514.1 - 0.16 12.0 0.1 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMEM169 PF15052.6 ORY05515.1 - 0.087 13.0 2.9 0.13 12.4 2.9 1.4 1 1 0 1 1 1 0 TMEM169 protein family Metallophos PF00149.28 ORY05516.1 - 9.7e-39 134.0 0.1 1.2e-38 133.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY05516.1 - 6.8e-23 80.9 0.2 1.7e-22 79.6 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L23eN PF03939.13 ORY05517.1 - 8e-24 83.6 7.3 1.4e-23 82.8 7.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORY05517.1 - 3.1e-14 53.1 1.2 1.3e-13 51.0 0.4 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 CTP_transf_like PF01467.26 ORY05518.1 - 2.4e-31 108.9 0.0 4.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 ORY05518.1 - 0.02 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5639) La PF05383.17 ORY05520.1 - 4.1e-10 39.5 0.3 7.1e-10 38.8 0.3 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 ORY05520.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nuc_sug_transp PF04142.15 ORY05521.1 - 8.7e-122 406.2 16.6 9.8e-122 406.0 16.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ORY05521.1 - 1.8e-09 37.9 28.9 4.7e-06 26.8 3.7 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 ORY05521.1 - 1.6e-08 34.1 15.6 3.5e-08 33.0 15.6 1.5 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 ORY05521.1 - 9.5e-06 25.0 19.0 1.5e-05 24.4 19.0 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EmrE PF13536.6 ORY05521.1 - 0.00023 20.9 1.4 0.00023 20.9 1.4 2.2 1 1 0 2 2 2 1 Putative multidrug resistance efflux transporter CRT-like PF08627.10 ORY05521.1 - 0.0029 16.6 7.1 0.0029 16.6 7.1 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Multi_Drug_Res PF00893.19 ORY05521.1 - 0.052 14.2 6.8 0.16 12.7 0.5 3.0 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF202 PF02656.15 ORY05521.1 - 0.29 11.6 4.2 3 8.4 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Peptidase_A24 PF01478.18 ORY05521.1 - 4.8 7.6 10.8 0.5 10.8 2.3 3.1 3 1 0 3 3 3 0 Type IV leader peptidase family SH3_1 PF00018.28 ORY05522.1 - 6.3e-10 38.5 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY05522.1 - 9.7e-09 35.0 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY05522.1 - 1.5e-08 34.2 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain YwiC PF14256.6 ORY05522.1 - 0.25 11.7 5.9 0.42 10.9 5.9 1.3 1 0 0 1 1 1 0 YwiC-like protein Acyltransferase PF01553.21 ORY05523.1 - 1.1e-25 89.8 0.0 4.1e-25 88.0 0.0 1.8 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 ORY05523.1 - 4.3e-19 68.4 0.8 8.7e-19 67.4 0.8 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus IQ PF00612.27 ORY05524.1 - 3.3e-11 42.0 17.3 0.00079 19.0 0.8 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif DUF16 PF01519.16 ORY05524.1 - 0.0031 18.0 6.5 0.67 10.5 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function DUF16 NPV_P10 PF05531.12 ORY05524.1 - 0.089 13.3 7.5 7.1 7.2 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 ORY05524.1 - 0.14 11.5 4.8 0.18 11.1 2.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4618 PF15397.6 ORY05524.1 - 0.18 11.2 10.8 1.3 8.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) LPP PF04728.13 ORY05524.1 - 0.41 11.1 4.9 13 6.3 0.1 3.3 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF641 PF04859.12 ORY05524.1 - 0.68 10.3 6.7 0.2 12.0 2.3 2.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 ORY05524.1 - 1.8 8.6 9.8 1.4 8.9 3.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 ORY05524.1 - 2.3 8.9 15.8 0.26 11.9 5.7 3.4 3 0 0 3 3 3 0 SlyX BLOC1_2 PF10046.9 ORY05524.1 - 2.5 8.5 10.7 1.1 9.6 0.2 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GvpK PF05121.12 ORY05524.1 - 4.1 7.5 10.4 1.7 8.8 2.1 2.8 3 0 0 3 3 3 0 Gas vesicle protein K DUF948 PF06103.11 ORY05524.1 - 4.9 7.5 4.9 40 4.6 1.9 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 ORY05524.1 - 5.8 6.8 11.5 8.1 6.3 3.1 3.2 3 0 0 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 ORY05524.1 - 7.6 6.9 11.1 1.5 9.2 4.2 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Csm1_N PF18504.1 ORY05524.1 - 8.1 6.9 12.0 40 4.6 5.6 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF1748 PF08520.10 ORY05525.1 - 2.3e-25 88.3 0.2 2.4e-25 88.2 0.2 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) ASCH PF04266.14 ORY05525.1 - 0.17 12.5 0.0 5.1 7.7 0.0 2.0 2 0 0 2 2 2 0 ASCH domain SWI-SNF_Ssr4 PF08549.10 ORY05526.1 - 3.9e-27 95.2 6.0 3.9e-27 95.2 6.0 2.9 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1750) DUF2353 PF09789.9 ORY05526.1 - 0.011 15.1 0.9 0.018 14.4 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Dabb PF07876.12 ORY05526.1 - 0.053 14.2 0.5 0.11 13.1 0.5 1.6 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Swi5 PF07061.11 ORY05526.1 - 0.3 11.2 2.1 0.64 10.1 2.1 1.6 1 0 0 1 1 1 0 Swi5 Peptidase_M28 PF04389.17 ORY05527.1 - 1.3e-38 132.7 0.0 1.8e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY05527.1 - 6.6e-14 51.7 1.2 1e-13 51.1 0.2 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 ORY05527.1 - 0.00024 20.9 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MMR_HSR1_C PF08438.10 ORY05528.1 - 9.5e-40 135.7 0.0 1.7e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ORY05528.1 - 1.9e-21 76.2 0.0 1.6e-20 73.3 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY05528.1 - 1.4e-08 34.4 0.1 4.1e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B TGS PF02824.21 ORY05528.1 - 0.00011 22.1 0.0 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 ORY05528.1 - 0.0038 17.3 0.8 0.019 15.0 0.0 2.6 4 0 0 4 4 4 1 Dynamin family ATP_bind_1 PF03029.17 ORY05528.1 - 0.01 15.6 0.3 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 ORY05528.1 - 0.017 15.0 0.2 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase NdhM PF10664.9 ORY05528.1 - 0.19 12.0 0.6 6 7.2 0.1 3.1 1 1 1 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M ThrE PF06738.12 ORY05529.1 - 8e-64 215.3 15.4 3.3e-56 190.4 3.3 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY05529.1 - 1e-14 54.7 24.2 2e-11 44.1 9.7 2.5 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE HPP PF04982.13 ORY05529.1 - 2.7 8.2 9.7 0.49 10.6 1.2 3.0 2 2 1 3 3 3 0 HPP family ThrE PF06738.12 ORY05530.1 - 1.4e-57 194.9 21.6 7e-52 176.2 2.8 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY05530.1 - 1e-10 41.9 28.3 1.2e-07 31.9 12.1 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF373 PF04123.13 ORY05530.1 - 0.011 15.2 6.4 0.068 12.6 4.5 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Sel1 PF08238.12 ORY05531.1 - 7.3e-25 86.9 21.5 2.4e-06 28.1 0.0 8.0 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 ORY05531.1 - 0.0037 17.4 1.3 2.1 8.6 0.6 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY05531.1 - 0.41 11.4 8.8 1e+02 3.9 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY05531.1 - 2.9 8.2 9.7 3.1 8.1 0.1 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY05531.1 - 7.9 6.5 10.8 6.6 6.7 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Svf1_C PF17187.4 ORY05533.1 - 1.6e-36 125.6 0.1 2.3e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORY05533.1 - 3.1e-16 59.8 0.1 5.5e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain zf-C2H2 PF00096.26 ORY05534.1 - 3.2e-09 36.7 7.7 1.8e-05 25.0 1.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY05534.1 - 2.8e-07 30.7 0.9 2.8e-07 30.7 0.9 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY05534.1 - 1.9e-06 28.2 6.5 0.018 15.9 1.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY05534.1 - 0.00061 20.4 0.6 0.17 12.5 0.0 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_7 PF15269.6 ORY05534.1 - 0.009 16.1 1.0 0.009 16.1 1.0 2.0 1 1 1 2 2 2 1 Zinc-finger zf-C2H2_8 PF15909.5 ORY05534.1 - 0.015 15.6 0.6 0.063 13.6 0.6 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY05534.1 - 0.052 13.7 1.0 0.066 13.4 1.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger Cyclin_N PF00134.23 ORY05535.1 - 0.0011 18.6 0.3 0.0042 16.8 0.3 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY05535.1 - 0.081 13.0 0.3 1.1 9.4 0.0 2.4 2 1 1 3 3 3 0 Cyclin, C-terminal domain SE PF08491.10 ORY05536.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase ADP_PFK_GK PF04587.15 ORY05536.1 - 0.19 10.3 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Cyclin PF08613.11 ORY05537.1 - 2.8e-09 37.6 1.3 2.6e-08 34.4 1.3 2.1 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY05537.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-C2H2 PF00096.26 ORY05538.1 - 1.5e-16 59.8 13.9 9.6e-06 25.8 2.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY05538.1 - 1.3e-15 57.0 12.8 2.8e-07 30.7 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY05538.1 - 4.7e-12 45.7 12.8 0.00013 22.5 2.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY05538.1 - 3.5e-08 33.2 11.5 0.00027 20.8 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY05538.1 - 2.4e-05 24.5 2.5 3.4e-05 24.0 1.2 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 ORY05538.1 - 3.7e-05 24.1 8.9 0.097 13.1 1.8 3.0 1 1 2 3 3 3 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORY05538.1 - 6.1e-05 23.2 2.1 2.6 8.4 1.7 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 ORY05538.1 - 8.9e-05 22.5 2.0 0.63 10.2 0.0 3.1 2 1 1 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 ORY05538.1 - 0.0024 17.6 4.9 0.16 11.8 0.1 2.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-LYAR PF08790.11 ORY05538.1 - 0.0025 17.7 6.3 2.7 7.9 0.9 3.2 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-AN1 PF01428.16 ORY05538.1 - 0.0042 17.2 11.0 0.32 11.2 4.7 3.0 1 1 1 2 2 2 1 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 ORY05538.1 - 0.0074 17.0 3.8 0.034 14.8 3.8 2.0 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 ORY05538.1 - 0.018 15.2 7.3 0.61 10.2 5.7 2.9 1 1 2 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 ORY05538.1 - 0.019 15.2 6.6 0.12 12.6 6.2 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain BolA PF01722.18 ORY05538.1 - 0.052 13.8 0.1 0.09 13.1 0.1 1.4 2 0 0 2 2 2 0 BolA-like protein zf_UBZ PF18439.1 ORY05538.1 - 0.056 13.0 3.1 2.2 7.9 0.8 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 ORY05538.1 - 0.06 13.4 0.4 0.071 13.1 0.4 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 ORY05538.1 - 0.26 11.7 4.5 30 5.2 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORY05538.1 - 0.53 10.3 0.2 0.53 10.3 0.2 3.5 3 1 0 3 3 3 0 zinc-finger of a C2HC-type CpXC PF14353.6 ORY05538.1 - 0.99 9.5 4.3 4.6 7.3 0.2 2.8 1 1 2 3 3 3 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 ORY05538.1 - 1.5 8.8 7.7 1.4 9.0 2.2 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_aberr PF17017.5 ORY05538.1 - 1.7 8.7 5.0 4.3 7.5 0.1 2.6 2 1 1 3 3 3 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORY05538.1 - 1.8 8.4 15.2 5.2 6.9 8.4 3.2 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 ORY05538.1 - 2 8.5 7.0 14 5.8 1.2 2.8 1 1 2 3 3 3 0 BED zinc finger zf-C2H2 PF00096.26 ORY05539.1 - 8.6e-25 85.8 16.4 5.4e-06 26.6 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY05539.1 - 4.1e-22 77.6 10.1 4.8e-07 29.9 0.4 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY05539.1 - 6.6e-16 57.6 15.7 0.0048 17.6 0.2 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 ORY05539.1 - 1.9e-09 38.0 7.5 0.088 13.4 0.1 4.0 1 1 3 4 4 4 3 FOXP coiled-coil domain zf-TRAF PF02176.18 ORY05539.1 - 4.6e-07 30.4 4.7 0.021 15.5 0.1 3.0 2 1 1 3 3 3 2 TRAF-type zinc finger zf-H2C2_5 PF13909.6 ORY05539.1 - 0.0019 17.9 0.3 0.0019 17.9 0.3 4.8 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORY05539.1 - 0.016 15.5 5.0 11 6.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY05539.1 - 0.017 15.5 6.9 9 6.8 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY05539.1 - 0.02 15.2 3.3 0.49 10.7 0.4 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY05539.1 - 0.041 14.0 3.5 18 5.4 0.1 3.6 1 1 2 3 3 3 0 Aberrant zinc-finger zf-CGNR PF11706.8 ORY05539.1 - 0.11 12.3 6.6 17 5.4 0.1 4.0 4 0 0 4 4 4 0 CGNR zinc finger zf-C2H2_6 PF13912.6 ORY05539.1 - 2.1 8.4 7.1 6 7.0 0.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Transpos_assoc PF13963.6 ORY05539.1 - 2.4 8.5 5.7 1 9.7 0.3 2.7 1 1 3 4 4 4 0 Transposase-associated domain Fapy_DNA_glyco PF01149.24 ORY05540.1 - 1.4e-31 109.5 0.0 2.7e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ORY05540.1 - 3.9e-17 62.0 0.0 7.1e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 ORY05540.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Homeodomain PF00046.29 ORY05541.1 - 1.7e-06 27.8 3.2 3e-06 27.0 1.7 2.3 2 0 0 2 2 2 1 Homeodomain Phage_Orf51 PF06194.11 ORY05542.1 - 0.014 15.4 1.4 0.36 10.9 0.2 2.2 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Rnk_N PF14760.6 ORY05542.1 - 0.029 14.8 0.8 9.7 6.8 0.1 3.5 5 0 0 5 5 5 0 Rnk N-terminus Pepsin-I3 PF06394.13 ORY05542.1 - 0.8 9.9 3.2 2.3 8.5 0.2 2.4 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain PH_9 PF15410.6 ORY05543.1 - 3.4e-29 101.6 0.0 8.3e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 ORY05543.1 - 3.4e-15 56.2 6.3 4.1e-14 52.7 4.8 3.0 2 1 0 2 2 2 1 Sec7 domain PH PF00169.29 ORY05543.1 - 2.5e-09 37.6 0.0 5.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Glycogen_syn PF05693.13 ORY05544.1 - 0 1104.7 0.1 0 1104.4 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 ORY05544.1 - 2e-06 27.5 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY05544.1 - 3.9e-06 27.0 0.2 7.9e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 ORY05544.1 - 4.5e-06 26.5 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 ORY05544.1 - 7.1e-05 23.3 0.1 0.00014 22.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ORY05544.1 - 0.00048 20.6 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Tube PF17212.3 ORY05545.1 - 0.00063 19.8 12.6 0.49 10.4 0.7 4.0 1 1 3 4 4 4 3 Tail tubular protein DUF5480 PF17576.2 ORY05545.1 - 0.0071 16.3 18.6 0.59 10.1 0.5 6.0 1 1 6 7 7 7 2 Family of unknown function (DUF5480) Rad33 PF08730.10 ORY05545.1 - 0.022 14.8 0.0 27 4.7 0.0 3.5 1 1 2 4 4 4 0 Rad33 DUF824 PF05688.11 ORY05545.1 - 0.024 14.5 5.1 7.3 6.5 0.1 4.3 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) Pox_D3 PF04580.13 ORY05545.1 - 0.08 12.6 4.3 30 4.1 0.1 3.8 2 1 2 4 4 4 0 Chordopoxvirinae D3 protein DUF5601 PF18151.1 ORY05545.1 - 0.094 13.0 0.3 1.6e+02 2.7 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) DUF4625 PF15418.6 ORY05545.1 - 0.13 12.5 9.4 4.6 7.5 0.3 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4625) DUF4889 PF16230.5 ORY05545.1 - 0.19 12.0 17.5 4.7 7.5 0.3 6.1 3 3 5 8 8 8 0 Domain of unknown function (DUF4889) DUF680 PF05079.12 ORY05545.1 - 0.52 11.0 14.3 12 6.7 1.3 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF680) VWD PF00094.25 ORY05545.1 - 0.83 9.9 19.9 3.1 8.1 5.2 3.8 1 1 3 4 4 4 0 von Willebrand factor type D domain MmgE_PrpD PF03972.14 ORY05545.1 - 8.6 4.8 9.9 17 3.8 0.2 3.7 2 2 1 4 4 4 0 MmgE/PrpD family DSPc PF00782.20 ORY05599.1 - 5e-06 26.4 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY05599.1 - 0.00054 19.6 0.0 0.00088 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Oxidored_molyb PF00174.19 ORY05600.1 - 1.2e-54 184.5 0.0 2e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 ORY05600.1 - 4.8e-33 113.5 0.0 4.7e-32 110.3 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY05600.1 - 3e-29 101.8 0.0 1e-28 100.1 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORY05600.1 - 1.3e-20 73.3 0.0 2.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mo-co_dimer PF03404.16 ORY05600.1 - 1.7e-17 63.7 0.0 4.6e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_6 PF08030.12 ORY05600.1 - 4.6e-05 23.6 0.0 8.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain BNR PF02012.20 ORY05600.1 - 0.08 13.0 0.2 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Cyclin_N PF00134.23 ORY05601.1 - 4e-20 71.9 1.8 5.5e-17 61.7 0.4 2.9 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORY05601.1 - 2.3e-05 24.4 0.1 0.087 12.9 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORY05601.1 - 0.00031 20.8 1.5 0.0033 17.5 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 ORY05601.1 - 0.021 15.2 0.3 0.095 13.1 0.3 2.1 1 1 0 1 1 1 0 Cyclin C-terminal domain TB2_DP1_HVA22 PF03134.19 ORY05602.1 - 1.1e-32 111.8 6.3 1.1e-32 111.8 6.3 1.9 2 0 0 2 2 2 1 TB2/DP1, HVA22 family SWIRM-assoc_2 PF16496.5 ORY05603.1 - 1.1e-56 192.6 1.0 2.2e-55 188.2 0.1 2.1 1 1 1 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 ORY05603.1 - 4.9e-25 87.7 0.1 1.1e-24 86.5 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ORY05603.1 - 2.6e-20 72.2 5.6 2.6e-20 72.2 5.6 1.8 2 0 0 2 2 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ORY05603.1 - 2.5e-13 50.0 0.0 5.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY05603.1 - 3.5e-07 30.4 2.7 2e-06 28.0 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 ORY05603.1 - 0.00054 19.7 3.8 0.00095 18.9 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Chromo PF00385.24 ORY05603.1 - 0.0074 16.2 0.3 0.026 14.4 0.3 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BRCT_2 PF16589.5 ORY05603.1 - 0.14 12.6 0.0 1.2 9.6 0.0 2.4 2 1 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain TRPM_tetra PF16519.5 ORY05603.1 - 0.27 11.3 2.4 0.67 10.1 2.4 1.7 1 0 0 1 1 1 0 Tetramerisation domain of TRPM DUF1664 PF07889.12 ORY05603.1 - 0.51 10.4 2.4 1.5 8.9 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) C1_2 PF03107.16 ORY05603.1 - 1.3 9.4 7.1 2.5 8.5 7.1 1.4 1 0 0 1 1 1 0 C1 domain Cluap1 PF10234.9 ORY05603.1 - 6.7 6.0 8.6 3.2 7.1 5.9 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 NDUFA12 PF05071.16 ORY05604.1 - 1.1e-29 103.1 9.4 1.3e-29 102.9 9.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ThiF PF00899.21 ORY05605.1 - 3.5e-74 249.2 0.0 5.1e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 ORY05605.1 - 2.1e-14 54.0 1.4 1.1e-07 32.0 0.2 2.8 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 ORY05605.1 - 6.6e-07 29.8 0.1 1.7e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 ORY05605.1 - 0.00017 22.0 0.0 0.00066 20.1 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ORY05605.1 - 0.00024 21.2 0.1 0.00054 20.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ORY05605.1 - 0.012 16.1 0.4 0.34 11.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ORY05605.1 - 0.032 14.5 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-C2H2_jaz PF12171.8 ORY05606.1 - 4.1e-05 23.7 0.0 6.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY05606.1 - 0.042 14.2 0.1 0.082 13.3 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORY05606.1 - 0.078 13.4 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AKAP95 PF04988.12 ORY05606.1 - 0.091 13.0 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF4674 PF15719.5 ORY05606.1 - 0.11 12.5 4.4 0.17 11.9 3.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) DUF2428 PF10350.9 ORY05607.1 - 4e-74 249.3 0.1 1.7e-73 247.2 0.0 2.2 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 ORY05607.1 - 2.5e-07 30.4 3.1 0.24 11.8 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 ORY05607.1 - 0.0001 22.6 0.5 6 7.3 0.0 4.8 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 ORY05607.1 - 0.17 12.5 0.4 35 5.0 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat DUF2423 PF10338.9 ORY05608.1 - 1.4e-16 60.4 4.7 1.4e-16 60.4 4.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 ORY05608.1 - 0.0054 17.3 17.3 0.016 15.8 17.3 1.8 1 1 0 1 1 1 1 Learning-associated protein RRM_1 PF00076.22 ORY05609.1 - 1.5e-45 152.9 0.1 1.5e-22 79.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 ORY05609.1 - 9.5e-19 68.3 0.1 2.5e-18 66.9 0.1 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 ORY05609.1 - 1.4e-05 24.9 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY05609.1 - 1.7e-05 24.8 0.0 0.022 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 ORY05609.1 - 0.00033 20.6 0.0 2.8 8.0 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 ORY05609.1 - 0.033 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 ORY05609.1 - 0.058 13.5 0.1 0.65 10.1 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif Presenilin PF01080.17 ORY05609.1 - 3.9 6.1 14.5 6.8 5.3 14.5 1.3 1 0 0 1 1 1 0 Presenilin LRR_8 PF13855.6 ORY05610.1 - 0.0089 15.8 10.9 6.4 6.6 0.1 5.8 6 1 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 ORY05610.1 - 0.014 15.4 9.8 14 6.0 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich repeat Fungal_trans PF04082.18 ORY05611.1 - 3e-31 108.4 1.9 3.8e-31 108.1 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY05611.1 - 9.1e-11 41.7 10.8 1.9e-10 40.7 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XTBD PF11952.8 ORY05612.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD GPI-anchored PF10342.9 ORY05613.1 - 3.1e-15 56.7 1.6 3.1e-15 56.7 1.6 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4726 PF15855.5 ORY05613.1 - 0.33 11.2 1.5 0.49 10.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) ABC_membrane_2 PF06472.15 ORY05614.1 - 4.6e-102 341.0 1.1 7.9e-102 340.3 1.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY05614.1 - 9.6e-20 71.5 0.0 1.9e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY05614.1 - 0.00011 22.1 0.1 0.00034 20.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY05614.1 - 0.0034 16.8 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY05614.1 - 0.0072 16.8 4.5 0.062 13.8 4.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY05614.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 ORY05614.1 - 0.077 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ORY05614.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AMP-binding PF00501.28 ORY05615.1 - 6.6e-49 166.6 0.0 3e-48 164.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 ORY05615.1 - 1.8e-30 106.8 0.0 4e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 ORY05615.1 - 0.00074 20.2 0.0 0.002 18.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY05615.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY05615.1 - 0.0021 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.11 ORY05615.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain PP-binding PF00550.25 ORY05615.1 - 0.12 12.8 0.0 7.6 7.0 0.0 2.6 1 1 0 1 1 1 0 Phosphopantetheine attachment site AMP-binding PF00501.28 ORY05616.1 - 0.035 12.7 0.1 4.1 5.9 0.0 2.1 1 1 1 2 2 2 0 AMP-binding enzyme Rotavirus_VP7 PF05868.11 ORY05616.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 AMP-binding PF00501.28 ORY05617.1 - 1.5e-34 119.3 0.0 2.5e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 ORY05617.1 - 2.1e-30 106.6 0.0 4e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 ORY05617.1 - 0.00036 20.8 0.0 0.00096 19.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 ORY05617.1 - 0.00074 20.2 0.0 0.0018 19.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY05617.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY05617.1 - 0.0022 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.11 ORY05617.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain AMP-binding PF00501.28 ORY05618.1 - 3.2e-48 164.4 0.0 4.9e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 ORY05618.1 - 2.3e-30 106.4 0.0 4.4e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 ORY05618.1 - 0.00042 20.6 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 ORY05618.1 - 0.00074 20.2 0.0 0.0019 18.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY05618.1 - 0.0015 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY05618.1 - 0.0021 17.8 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.11 ORY05618.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain SET PF00856.28 ORY05619.1 - 1.4e-05 25.5 0.0 2.9e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 SET domain Pox_I5 PF04713.12 ORY05620.1 - 0.076 13.1 0.1 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus protein I5 Lysis_col PF02402.16 ORY05620.1 - 0.088 12.5 0.8 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 Lysis protein Ribosomal_S8e PF01201.22 ORY05621.1 - 2.4e-58 196.2 1.9 2.8e-58 196.0 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Pkinase PF00069.25 ORY05622.1 - 4.3e-46 157.4 0.4 1.6e-23 83.4 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05622.1 - 1.1e-14 54.4 0.9 4e-11 42.7 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 ORY05622.1 - 0.029 13.9 0.1 0.075 12.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 ORY05622.1 - 0.095 11.4 0.3 0.19 10.5 0.3 1.7 1 1 0 1 1 1 0 Fungal protein kinase PhoLip_ATPase_C PF16212.5 ORY05623.1 - 2.9e-68 230.3 36.0 2.9e-68 230.3 36.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY05623.1 - 1e-24 86.0 3.1 1e-24 86.0 3.1 3.2 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY05623.1 - 5.2e-12 45.7 0.0 1e-10 41.5 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY05623.1 - 9.9e-10 39.1 0.1 0.0021 18.4 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY05623.1 - 1.6e-07 31.1 0.0 1.6e-07 31.1 0.0 2.6 3 1 2 5 5 5 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY05623.1 - 0.00015 21.6 0.2 0.0004 20.2 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Helicase_C PF00271.31 ORY05624.1 - 4.4e-18 65.6 0.1 5.9e-17 62.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY05624.1 - 3.3e-14 53.0 0.2 6.8e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 ORY05624.1 - 1.4e-10 41.7 2.6 4e-10 40.3 2.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding KLRAQ PF10205.9 ORY05624.1 - 0.0058 16.8 2.8 0.0071 16.6 1.3 2.0 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein ResIII PF04851.15 ORY05624.1 - 0.02 14.9 0.1 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CENP-F_leu_zip PF10473.9 ORY05624.1 - 0.086 12.9 6.7 0.2 11.6 6.7 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 ORY05624.1 - 0.88 9.1 5.3 1.6 8.2 5.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain LPMO_10 PF03067.15 ORY05625.1 - 9.9e-06 26.3 0.1 5.6e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY05625.1 - 0.0016 18.4 0.0 0.025 14.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ribosomal_L7Ae PF01248.26 ORY05626.1 - 6.1e-24 83.6 2.2 7.7e-24 83.3 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 ORY05626.1 - 0.01 15.8 0.3 0.02 14.8 0.3 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GalP_UDP_tr_C PF02744.17 ORY05626.1 - 0.13 11.9 0.2 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain C2 PF00168.30 ORY05627.1 - 7.6e-17 61.5 0.0 8.9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain MeaB PF03308.16 ORY05629.1 - 2.8e-95 318.3 0.0 3.4e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ORY05629.1 - 5e-05 23.0 0.1 0.00026 20.6 0.1 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 ORY05629.1 - 0.00039 20.5 0.0 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ORY05629.1 - 0.0011 18.8 1.2 0.0038 17.0 0.0 2.3 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 ORY05629.1 - 0.0033 17.2 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 ORY05629.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 ORY05629.1 - 0.0065 16.0 0.8 0.057 12.9 0.8 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_29 PF13555.6 ORY05629.1 - 0.015 15.0 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 ORY05629.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 ORY05629.1 - 0.02 15.4 1.3 0.14 12.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 ORY05629.1 - 0.025 14.2 0.1 0.069 12.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 ORY05629.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 ORY05629.1 - 0.029 14.8 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY05629.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ORY05629.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 ORY05629.1 - 0.07 12.9 0.0 0.07 12.9 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ORY05629.1 - 0.12 12.8 0.0 0.35 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 ORY05629.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 ORY05629.1 - 0.19 12.2 1.5 0.95 10.0 0.1 2.5 2 1 1 3 3 3 0 ABC transporter LRR_8 PF13855.6 ORY05630.1 - 4.5e-43 144.8 64.8 9.6e-10 38.1 0.7 9.0 3 2 7 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 ORY05630.1 - 2.2e-33 113.7 74.6 1.1e-07 32.0 0.7 11.1 2 2 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY05630.1 - 6.8e-10 38.1 49.3 0.98 10.2 0.7 14.6 12 2 2 14 14 14 6 Leucine Rich Repeat LRR_9 PF14580.6 ORY05630.1 - 1.4e-05 24.6 27.3 0.0025 17.3 1.9 5.6 2 2 4 6 6 6 4 Leucine-rich repeat DUF2322 PF10084.9 ORY05630.1 - 0.03 14.3 0.5 2.5 8.2 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) SLX9 PF15341.6 ORY05631.1 - 1.3e-19 70.8 16.8 2e-19 70.3 16.8 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 RNB PF00773.19 ORY05631.1 - 0.029 13.7 2.4 0.033 13.5 2.4 1.2 1 0 0 1 1 1 0 RNB domain Tnp_P_element_C PF12596.8 ORY05631.1 - 0.052 14.1 0.6 0.052 14.1 0.6 2.1 1 1 1 2 2 2 0 87kDa Transposase PDDEXK_2 PF12784.7 ORY05631.1 - 0.097 12.2 4.5 0.15 11.6 4.5 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Aa_trans PF01490.18 ORY05632.1 - 5.4e-55 186.8 33.3 6.2e-55 186.6 33.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY05632.1 - 8.5e-08 31.4 22.5 8.5e-08 31.4 22.5 2.4 3 0 0 3 3 3 1 Amino acid permease Spore_permease PF03845.13 ORY05632.1 - 0.00015 20.7 17.3 0.00015 20.7 17.3 1.9 2 0 0 2 2 2 1 Spore germination protein ERGIC_N PF13850.6 ORY05632.1 - 1.8 9.0 9.8 0.11 12.8 0.7 3.4 4 0 0 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Usp PF00582.26 ORY05633.1 - 1.1e-12 48.7 0.0 1.3e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family EMC3_TMCO1 PF01956.16 ORY05634.1 - 9.2e-52 175.2 0.6 1.2e-51 174.8 0.6 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like AAA PF00004.29 ORY05635.1 - 5.9e-57 191.8 0.2 4.3e-28 98.4 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY05635.1 - 3.4e-16 58.8 0.2 2e-11 43.5 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY05635.1 - 4.5e-10 40.2 0.8 0.0062 16.9 0.1 4.1 2 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 ORY05635.1 - 9.7e-09 35.2 0.0 7.8e-05 22.5 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY05635.1 - 1.5e-08 35.0 0.2 0.0065 16.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORY05635.1 - 3.1e-08 33.2 0.3 0.0011 18.2 0.0 2.4 2 1 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 ORY05635.1 - 1.2e-07 31.8 0.6 0.081 12.8 0.1 3.8 3 1 0 3 3 3 2 NACHT domain AAA_33 PF13671.6 ORY05635.1 - 2.5e-07 30.9 0.0 0.0029 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ORY05635.1 - 3.3e-07 30.2 0.0 0.043 13.5 0.0 2.8 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 ORY05635.1 - 5.2e-07 30.3 0.0 0.0074 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY05635.1 - 4.1e-06 26.8 0.1 0.15 12.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY05635.1 - 4.3e-06 26.4 0.9 0.03 13.9 0.0 4.1 3 1 1 4 4 4 1 AAA domain AAA_7 PF12775.7 ORY05635.1 - 8e-06 25.5 0.0 0.029 13.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY05635.1 - 2.3e-05 23.9 0.8 0.16 11.3 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORY05635.1 - 2.4e-05 24.3 0.0 0.05 13.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 ORY05635.1 - 2.7e-05 23.6 0.3 0.32 10.3 0.1 2.7 2 1 0 2 2 2 2 KaiC AAA_2 PF07724.14 ORY05635.1 - 2.8e-05 24.3 0.0 0.063 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 ORY05635.1 - 3.3e-05 24.2 0.0 0.075 13.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 ORY05635.1 - 3.9e-05 23.7 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORY05635.1 - 0.00011 21.6 0.1 0.37 10.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 ORY05635.1 - 0.00015 22.1 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY05635.1 - 0.00015 21.5 0.2 0.09 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY05635.1 - 0.00034 21.1 0.0 0.05 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORY05635.1 - 0.0011 18.9 0.4 3.1 7.7 0.0 3.2 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 ORY05635.1 - 0.0019 18.0 0.1 0.47 10.1 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 ORY05635.1 - 0.002 17.9 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 ORY05635.1 - 0.0042 16.9 0.1 1.2 9.0 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY05635.1 - 0.0047 16.1 0.1 0.56 9.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 ORY05635.1 - 0.0057 17.2 0.5 3.3 8.2 0.0 2.7 2 1 0 2 2 2 1 ABC transporter DUF2075 PF09848.9 ORY05635.1 - 0.006 15.9 0.1 3 7.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 ORY05635.1 - 0.01 15.0 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 ORY05635.1 - 0.012 15.3 2.1 4 7.1 0.0 3.7 4 1 1 5 5 3 0 Guanylate kinase AAA_19 PF13245.6 ORY05635.1 - 0.014 15.8 1.0 2.9 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY05635.1 - 0.014 14.8 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 ORY05635.1 - 0.017 15.0 0.7 5.7 6.8 0.1 2.7 3 0 0 3 3 2 0 NTPase DAP3 PF10236.9 ORY05635.1 - 0.018 14.2 0.1 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 ORY05635.1 - 0.024 14.4 0.1 9.3 6.1 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY05635.1 - 0.027 14.2 0.5 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORY05635.1 - 0.031 14.0 0.0 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 ORY05635.1 - 0.037 13.8 0.6 7 6.4 0.1 3.1 2 2 0 2 2 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 ORY05635.1 - 0.044 13.9 0.2 14 5.8 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase TniB PF05621.11 ORY05635.1 - 0.059 12.8 0.0 8.1 5.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein DnaB_C PF03796.15 ORY05635.1 - 0.11 11.9 0.0 2.9 7.2 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Parvo_NS1 PF01057.17 ORY05635.1 - 0.11 11.6 0.0 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 cobW PF02492.19 ORY05635.1 - 0.13 11.9 0.5 7.1 6.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glycos_trans_3N PF02885.17 ORY05636.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Mito_carr PF00153.27 ORY05637.1 - 1e-72 240.1 0.7 2.3e-23 81.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY05637.1 - 0.034 13.3 2.4 8.3 5.5 0.1 3.2 2 1 0 3 3 3 0 Gammaproteobacterial serine protease GATA PF00320.27 ORY05638.1 - 6.6e-17 60.8 2.7 8.1e-17 60.5 2.7 1.1 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY05638.1 - 0.00087 18.8 0.7 0.0012 18.4 0.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 ORY05638.1 - 0.0017 18.5 0.5 0.0018 18.3 0.5 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-RRN7 PF11781.8 ORY05638.1 - 0.011 15.4 1.9 0.018 14.7 1.9 1.4 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 ORY05638.1 - 0.012 15.8 0.3 0.015 15.5 0.3 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-FCS PF06467.14 ORY05638.1 - 0.041 13.8 0.9 0.96 9.4 0.0 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn-ribbon_8 PF09723.10 ORY05638.1 - 0.043 13.9 0.1 0.055 13.6 0.1 1.2 1 0 0 1 1 1 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 ORY05638.1 - 0.047 13.6 0.7 0.06 13.2 0.7 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 MoCF_biosynth PF00994.24 ORY05639.1 - 3.7e-32 111.0 0.0 7.2e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cation_efflux PF01545.21 ORY05640.1 - 2.9e-53 180.6 4.5 3.7e-53 180.2 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3915 PF13054.6 ORY05641.1 - 0.97 9.4 3.9 4.5 7.3 3.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) UMP1 PF05348.11 ORY05642.1 - 4.4e-45 152.7 0.4 5.3e-45 152.4 0.4 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosomal_S19e PF01090.19 ORY05643.1 - 4.4e-59 198.1 0.2 4.9e-59 197.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e tRNA-synt_2c PF01411.19 ORY05644.1 - 3.7e-162 540.7 0.0 2.4e-155 518.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY05644.1 - 4e-15 55.6 0.1 8.4e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORY05644.1 - 6.1e-09 36.4 0.0 1.4e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 DHHA1 domain Pox_polyA_pol_N PF12630.7 ORY05644.1 - 0.088 13.2 0.6 1.1 9.7 0.1 2.7 3 0 0 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain BSD PF03909.17 ORY05645.1 - 2.3e-14 53.1 0.0 2.3e-14 53.1 0.0 2.7 4 0 0 4 4 4 1 BSD domain Minor_capsid_3 PF12691.7 ORY05645.1 - 0.01 16.2 0.1 0.03 14.7 0.1 1.7 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Vps54 PF07928.12 ORY05645.1 - 0.051 14.0 0.4 0.3 11.5 0.2 2.2 2 0 0 2 2 2 0 Vps54-like protein CemA PF03040.14 ORY05645.1 - 0.081 12.9 1.4 0.16 11.9 1.4 1.4 1 0 0 1 1 1 0 CemA family Cellulase PF00150.18 ORY05646.1 - 4e-20 72.4 1.6 7.7e-10 38.7 0.3 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY05646.1 - 1.1e-12 48.3 0.0 2.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 ORY05646.1 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 zf-C3HC4_3 PF13920.6 ORY05647.1 - 7.4e-09 35.3 3.9 1.3e-08 34.5 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY05647.1 - 7.5e-06 25.7 5.3 1.5e-05 24.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY05647.1 - 4.2e-05 23.3 4.9 8.2e-05 22.4 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY05647.1 - 6.4e-05 22.7 4.9 0.00012 21.9 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY05647.1 - 7.4e-05 23.0 5.8 0.00013 22.2 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY05647.1 - 0.0047 16.9 3.9 0.0093 15.9 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain V-ATPase_G PF03179.15 ORY05647.1 - 0.012 16.1 0.1 0.045 14.3 0.1 1.9 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit zf-RING_UBOX PF13445.6 ORY05647.1 - 0.021 14.8 3.9 0.057 13.4 3.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Nucleoporin_FG PF13634.6 ORY05647.1 - 0.023 15.5 4.2 0.043 14.7 3.4 2.0 1 1 0 1 1 1 0 Nucleoporin FG repeat region RhoGAP-FF1 PF16512.5 ORY05647.1 - 0.066 13.9 0.5 0.85 10.3 0.1 2.5 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain zf-C3HC4_5 PF17121.5 ORY05647.1 - 0.096 12.6 0.6 0.23 11.4 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 ORY05647.1 - 0.16 11.6 1.6 0.36 10.5 1.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 ORY05647.1 - 0.44 10.4 4.1 0.88 9.4 4.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lectin_leg-like PF03388.13 ORY05648.1 - 2.9e-64 216.5 0.1 3.4e-64 216.4 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ORY05648.1 - 3.7e-06 26.6 0.0 0.00012 21.8 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain Bact_lectin PF18483.1 ORY05648.1 - 9.3e-06 25.8 0.1 1.3e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin SRF-TF PF00319.18 ORY05649.1 - 1.1e-21 76.1 0.1 1.6e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAP PF07174.11 ORY05649.1 - 0.0012 18.3 0.1 0.0016 18.0 0.1 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) PIG-P PF08510.12 ORY05650.1 - 9e-34 116.0 6.5 8e-33 112.9 6.5 1.9 1 1 0 1 1 1 1 PIG-P Ribosomal_L34e PF01199.18 ORY05651.1 - 3.4e-46 155.5 3.9 4.7e-46 155.0 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e ArsA_ATPase PF02374.15 ORY05652.1 - 1.3e-112 375.9 0.5 1.6e-112 375.7 0.5 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY05652.1 - 8.1e-12 45.4 0.3 9.9e-11 41.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 ORY05652.1 - 1.2e-10 41.5 0.0 5.1e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ORY05652.1 - 4.8e-05 23.0 0.0 0.00011 21.7 0.0 1.5 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 ORY05652.1 - 0.00014 21.4 0.4 0.00078 19.0 0.1 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 ORY05652.1 - 0.0002 20.9 0.0 0.00043 19.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 ORY05652.1 - 0.00056 19.6 0.2 0.0025 17.5 0.1 2.0 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 ORY05652.1 - 0.004 16.7 0.1 0.023 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORY05652.1 - 0.09 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 ORY05652.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 ORY05652.1 - 0.19 12.3 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP_SPB PF02978.19 ORY05652.1 - 3.2 8.4 6.9 1.3 9.7 1.5 2.4 2 1 0 2 2 2 0 Signal peptide binding domain tRNA_m1G_MT PF01746.21 ORY05653.1 - 4.3e-33 114.7 0.2 6.4e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Orbi_VP6 PF01516.16 ORY05653.1 - 0.0042 16.6 0.2 0.0063 16.1 0.2 1.2 1 0 0 1 1 1 1 Orbivirus helicase VP6 SH3-RhoG_link PF16609.5 ORY05653.1 - 0.026 14.2 0.7 0.038 13.7 0.7 1.2 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region GcrA PF07750.11 ORY05653.1 - 0.056 13.9 0.2 0.099 13.1 0.2 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator Gal11_ABD1 PF18535.1 ORY05653.1 - 0.076 13.1 1.2 0.19 11.8 1.2 1.6 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) PRP3 PF08572.10 ORY05653.1 - 0.32 10.7 7.3 0.52 10.0 5.9 2.0 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) DnaJ_C PF01556.18 ORY05654.1 - 6.6e-44 149.6 1.1 8.7e-44 149.2 1.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY05654.1 - 1.4e-26 92.4 2.4 2.6e-26 91.5 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY05654.1 - 1.8e-17 63.5 19.6 2.9e-17 62.8 19.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY05654.1 - 0.022 14.7 10.1 0.13 12.3 1.2 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORY05654.1 - 0.25 11.4 11.9 2.2 8.3 3.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CPSase_L_D2 PF02786.17 ORY05655.1 - 3.1e-108 360.1 0.1 2.8e-84 281.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ORY05655.1 - 1.3e-41 141.8 0.1 3.7e-41 140.3 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 ORY05655.1 - 2.2e-19 69.6 0.1 9e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY05655.1 - 2e-14 53.6 0.3 7.4e-08 32.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ORY05655.1 - 2.1e-10 40.5 0.0 0.00051 19.8 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 ORY05655.1 - 4e-07 30.1 0.0 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain RimK PF08443.11 ORY05655.1 - 3.9e-06 26.6 0.0 0.027 14.1 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 ORY05655.1 - 7.5e-06 25.6 0.0 0.03 13.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 ORY05655.1 - 0.0023 17.8 1.7 0.75 9.5 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_M17_N PF02789.17 ORY05655.1 - 0.01 15.7 0.2 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DEAD PF00270.29 ORY05655.1 - 0.053 13.3 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase MCPsignal PF00015.21 ORY05655.1 - 0.055 13.3 0.2 0.26 11.1 0.0 2.2 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ATP-grasp_2 PF08442.10 ORY05655.1 - 0.082 12.5 0.0 4.6 6.8 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp domain TCO89 PF10452.9 ORY05657.1 - 1.2e-07 31.1 1.0 1.2e-07 31.1 1.0 1.6 2 0 0 2 2 2 1 TORC1 subunit TCO89 Ribosomal_L26 PF16906.5 ORY05659.1 - 1.3e-37 128.1 2.5 1.6e-37 127.8 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY05659.1 - 1.6e-10 40.6 2.0 5e-10 39.0 1.9 1.8 2 0 0 2 2 2 1 KOW motif Ctr PF04145.15 ORY05660.1 - 5.9e-25 88.6 9.5 2.4e-23 83.4 9.5 2.3 1 1 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.6 ORY05660.1 - 0.1 12.7 1.4 0.23 11.6 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) SET PF00856.28 ORY05661.1 - 4.6e-09 36.9 0.1 8.4e-08 32.8 0.1 2.3 1 1 0 1 1 1 1 SET domain EF-hand_1 PF00036.32 ORY05662.1 - 1.4e-18 65.0 3.1 0.00029 20.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY05662.1 - 2.3e-14 52.0 3.1 0.0086 15.9 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 ORY05662.1 - 2.5e-10 40.7 5.5 0.0002 21.7 0.1 4.1 2 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY05662.1 - 3.5e-09 35.7 6.7 0.0066 15.9 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORY05662.1 - 1.1e-05 25.1 2.2 0.022 14.6 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY05662.1 - 1.6e-05 25.2 4.5 0.079 13.3 0.3 3.6 1 1 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region zf-UBR PF02207.20 ORY05662.1 - 0.36 11.0 12.6 0.77 10.0 4.7 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) C1_1 PF00130.22 ORY05662.1 - 0.42 10.5 14.7 0.69 9.8 4.5 3.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1272 PF06906.11 ORY05662.1 - 4.1 7.6 13.9 4.3 7.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Rotamase_3 PF13616.6 ORY05663.1 - 1.4e-16 61.0 0.1 3e-16 60.0 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORY05663.1 - 3e-15 57.0 0.0 4.2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ORY05663.1 - 0.004 18.0 0.0 0.0066 17.3 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF3137 PF11335.8 ORY05663.1 - 0.053 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Apolipoprotein PF01442.18 ORY05664.1 - 0.017 15.0 0.6 0.023 14.5 0.6 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Peptidase_S49_N PF08496.10 ORY05664.1 - 0.021 14.9 0.3 0.03 14.4 0.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4604 PF15377.6 ORY05665.1 - 1.3e-21 77.8 16.7 1.6e-21 77.5 16.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Ribosomal_L18p PF00861.22 ORY05665.1 - 0.053 13.9 0.3 0.091 13.1 0.1 1.4 1 1 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Suf PF05843.14 ORY05665.1 - 0.23 11.4 6.0 0.26 11.3 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAS_9 PF13426.7 ORY05666.1 - 1.3e-23 83.3 0.0 3.7e-15 56.0 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 ORY05666.1 - 4e-20 71.9 0.0 1.6e-14 53.9 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 ORY05666.1 - 3.7e-14 52.7 0.0 6.5e-05 22.9 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_11 PF14598.6 ORY05666.1 - 7.9e-14 51.8 0.1 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ORY05666.1 - 4.8e-05 23.6 0.0 0.039 14.2 0.0 3.0 3 0 0 3 3 3 2 PAS fold GATA PF00320.27 ORY05666.1 - 0.00012 21.6 2.0 0.00025 20.6 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_8 PF13188.7 ORY05666.1 - 0.0019 18.2 0.0 0.26 11.4 0.0 2.6 2 0 0 2 2 2 1 PAS domain CHAD PF05235.14 ORY05666.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 CHAD domain Peptidase_M20 PF01546.28 ORY05667.1 - 5.9e-35 120.9 0.0 7.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY05667.1 - 1.3e-13 50.8 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain LPMO_10 PF03067.15 ORY05668.1 - 0.00094 19.9 0.1 0.0017 19.1 0.1 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY05668.1 - 0.0011 19.0 0.0 0.0098 15.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 NifU_N PF01592.16 ORY05669.1 - 3.7e-54 182.3 0.0 4.3e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DAO PF01266.24 ORY05670.1 - 3e-34 119.2 0.0 3.6e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY05670.1 - 2.4e-07 30.9 0.2 5.1e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY05670.1 - 8.5e-05 23.0 0.1 0.00028 21.4 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY05670.1 - 8.9e-05 21.7 0.2 0.00016 20.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORY05670.1 - 0.00034 21.0 0.0 0.00081 19.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ORY05670.1 - 0.00035 19.9 0.0 0.00073 18.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY05670.1 - 0.00075 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORY05670.1 - 0.00077 18.8 0.1 0.0013 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORY05670.1 - 0.0013 17.9 0.4 0.0021 17.2 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ORY05670.1 - 0.002 17.4 0.1 0.02 14.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY05670.1 - 0.0038 16.0 0.0 0.0067 15.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 ORY05670.1 - 0.0078 15.1 0.5 0.2 10.5 0.7 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 ORY05670.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 ORY05670.1 - 0.045 13.4 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ORY05670.1 - 0.045 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb2_6 PF00562.28 ORY05670.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 GST_C_2 PF13410.6 ORY05671.1 - 6.5e-06 26.1 0.2 1.4e-05 25.0 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY05671.1 - 2.8e-05 24.4 0.0 4.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY05671.1 - 5.3e-05 23.6 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY05671.1 - 0.00035 20.7 0.1 0.0013 18.9 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY05671.1 - 0.0025 18.0 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Gelsolin PF00626.22 ORY05672.1 - 2.4e-29 101.0 0.1 2e-10 40.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat AAA PF00004.29 ORY05734.1 - 4.2e-06 27.2 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol_A_exo1 PF01612.20 ORY05734.1 - 0.00033 20.4 0.6 0.0017 18.1 0.1 2.3 2 0 0 2 2 2 1 3'-5' exonuclease MMR_HSR1 PF01926.23 ORY05734.1 - 0.0014 18.7 0.0 0.0091 16.1 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ORY05734.1 - 0.003 17.1 0.0 0.029 14.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ORY05734.1 - 0.0052 17.2 0.0 0.023 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY05734.1 - 0.0078 16.8 0.1 0.024 15.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 ORY05734.1 - 0.009 15.4 0.0 1.7 8.0 0.0 2.8 3 0 0 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 ORY05734.1 - 0.043 14.1 0.3 0.95 9.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY05734.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 ORY05734.1 - 0.061 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 ORY05734.1 - 0.07 12.5 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 ORY05734.1 - 0.09 12.3 0.0 0.75 9.3 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORY05734.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ORY05734.1 - 0.11 12.0 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_33 PF13671.6 ORY05734.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 ORY05734.1 - 0.14 12.3 0.0 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) T2SSE PF00437.20 ORY05734.1 - 0.15 11.1 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-C2H2 PF00096.26 ORY05735.1 - 1.9e-11 43.8 9.8 6.3e-06 26.4 3.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY05735.1 - 9.1e-10 38.5 8.8 4e-05 24.1 2.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY05735.1 - 1.8e-08 34.4 14.9 3.8e-07 30.2 3.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORY05735.1 - 6e-06 26.5 1.9 6e-06 26.5 1.9 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY05735.1 - 8.7e-05 22.4 2.3 8.7e-05 22.4 2.3 2.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY05735.1 - 0.00061 20.0 5.0 0.0012 19.1 1.5 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY05735.1 - 0.0086 15.8 6.7 0.12 12.2 0.2 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 ORY05735.1 - 0.091 12.9 2.1 3.3 7.9 2.8 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 ORY05735.1 - 0.1 12.9 2.4 0.16 12.3 0.8 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORY05735.1 - 0.2 11.7 4.7 4.8 7.3 4.7 2.2 1 1 0 1 1 1 0 BED zinc finger Zn_ribbon_SprT PF17283.2 ORY05735.1 - 0.21 11.5 5.7 0.24 11.3 1.1 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 ORY05735.1 - 0.29 11.1 7.4 2.4 8.2 2.9 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Tcp10_C PF07202.13 ORY05736.1 - 1.1e-36 126.4 2.5 1.1e-36 126.4 2.5 2.2 2 0 0 2 2 2 1 T-complex protein 10 C-terminus bZIP_2 PF07716.15 ORY05736.1 - 0.056 13.5 0.7 0.056 13.5 0.7 4.7 3 1 3 6 6 6 0 Basic region leucine zipper Tfb4 PF03850.14 ORY05736.1 - 1.5 8.2 5.3 9.5 5.6 3.4 2.1 2 0 0 2 2 2 0 Transcription factor Tfb4 LAMTOR PF15454.6 ORY05736.1 - 1.7 9.3 6.1 4 8.1 3.9 2.8 1 1 1 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator TSC22 PF01166.18 ORY05736.1 - 5.3 7.4 15.5 4.3 7.7 2.7 3.8 3 1 1 4 4 4 0 TSC-22/dip/bun family Sec39 PF08314.11 ORY05737.1 - 9.1e-83 279.0 0.0 1.4e-82 278.4 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF3900 PF13039.6 ORY05737.1 - 0.051 13.5 0.1 0.16 11.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3900) Metallophos PF00149.28 ORY05738.1 - 4.4e-35 122.0 0.0 6.4e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY05738.1 - 6.2e-18 65.0 0.0 1.6e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L6 PF00347.23 ORY05739.1 - 1.6e-32 112.0 5.3 1.1e-17 64.5 1.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Nmad5 PF18757.1 ORY05739.1 - 0.025 14.8 0.1 0.03 14.5 0.1 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 Exotox-A_cataly PF09009.10 ORY05739.1 - 0.039 13.7 0.3 0.6 9.8 0.1 2.3 2 1 1 3 3 3 0 Exotoxin A catalytic KH_1 PF00013.29 ORY05739.1 - 6.3 6.7 8.0 0.52 10.2 0.6 2.5 3 0 0 3 3 3 0 KH domain Aminotran_5 PF00266.19 ORY05740.1 - 8.9e-14 51.2 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY05740.1 - 0.097 12.0 0.0 0.21 10.9 0.0 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ORY05740.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Paf67 PF10255.9 ORY05741.1 - 0.028 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 CbiK PF06180.11 ORY05741.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) TPR_2 PF07719.17 ORY05741.1 - 0.21 11.8 0.1 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pribosyltran_N PF13793.6 ORY05742.1 - 8.2e-43 145.0 0.1 3.4e-42 143.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY05742.1 - 2.3e-39 135.4 0.3 1.2e-32 113.4 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY05742.1 - 5.6e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Urate_ox_N PF06181.11 ORY05743.1 - 0.037 13.4 0.1 0.049 13.0 0.1 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal Abhydrolase_3 PF07859.13 ORY05745.1 - 3.8e-32 111.8 0.0 1.1e-31 110.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY05745.1 - 1.8e-10 40.2 0.0 7.8e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 ORY05745.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY05745.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family PriCT_1 PF08708.11 ORY05746.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Spc7 PF08317.11 ORY05748.1 - 3.3e-51 174.0 17.6 3.3e-51 174.0 17.6 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 ORY05748.1 - 0.026 14.6 4.0 0.068 13.2 4.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 ORY05748.1 - 0.45 10.9 5.5 13 6.2 0.2 2.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A FUSC PF04632.12 ORY05748.1 - 1.1 7.8 2.0 1.7 7.1 2.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 ORY05748.1 - 2.8 8.0 6.4 9.9 6.2 6.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 ORY05748.1 - 4.1 7.4 7.0 4.3 7.3 2.6 2.9 1 1 0 2 2 2 0 Sec20 DUF948 PF06103.11 ORY05748.1 - 6.7 7.0 7.2 6.5 7.1 2.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.27 ORY05749.1 - 4.3e-61 202.9 0.2 1.6e-19 69.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY05749.1 - 0.063 12.4 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease TPR_2 PF07719.17 ORY05751.1 - 0.02 15.0 0.2 0.066 13.3 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4791 PF16039.5 ORY05751.1 - 0.031 13.8 0.2 0.68 9.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) TPR_1 PF00515.28 ORY05751.1 - 0.032 14.0 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Dynein_heavy PF03028.15 ORY05752.1 - 0.0094 16.0 0.2 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain EF-G-binding_N PF07299.11 ORY05752.1 - 0.036 14.6 0.3 0.11 13.1 0.1 1.8 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF4487 PF14868.6 ORY05752.1 - 0.066 12.0 0.3 2.1 7.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) Rad9 PF04139.13 ORY05753.1 - 3.2e-66 223.3 0.0 4.7e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Rad9 Tyrosinase PF00264.20 ORY05754.1 - 6.5e-50 170.5 1.9 1.2e-49 169.6 1.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase WD40 PF00400.32 ORY05755.1 - 4.3e-45 150.8 10.1 8.6e-07 29.6 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY05755.1 - 1.2e-14 54.4 0.4 0.15 12.3 0.0 5.5 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY05755.1 - 2e-09 37.6 0.5 2e-05 24.6 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 ORY05755.1 - 6.3e-06 25.9 0.5 0.0001 22.0 0.4 2.2 2 0 0 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.14 ORY05755.1 - 8.4e-05 21.8 0.4 0.16 11.0 0.6 2.1 1 1 1 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 ORY05755.1 - 0.00021 21.1 0.2 0.085 12.8 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ORY05755.1 - 0.00063 19.2 0.0 1.6 8.0 0.0 3.6 2 1 2 4 4 4 1 WD40-like domain Nup160 PF11715.8 ORY05755.1 - 0.00063 18.5 5.3 1.8 7.1 0.0 4.3 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY05755.1 - 0.0014 17.6 0.1 0.71 8.8 0.0 4.1 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY05755.1 - 0.0023 16.5 1.7 0.004 15.7 0.6 1.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 ORY05755.1 - 0.028 14.9 1.5 1.3 9.6 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Zn_clus PF00172.18 ORY05757.1 - 9e-05 22.5 10.5 0.00016 21.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyltransferase PF01553.21 ORY05758.1 - 1.4e-10 40.9 0.0 8.4e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Gpr1_Fun34_YaaH PF01184.19 ORY05758.1 - 0.21 11.2 3.4 0.37 10.4 3.4 1.3 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family GATA PF00320.27 ORY05759.1 - 1e-16 60.2 8.0 1e-16 60.2 8.0 2.5 3 0 0 3 3 3 1 GATA zinc finger PAS_3 PF08447.12 ORY05759.1 - 4.6e-14 52.5 0.0 7.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORY05759.1 - 2e-10 40.7 0.0 3.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ORY05759.1 - 1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 ORY05759.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ORY05759.1 - 0.00045 20.4 0.0 0.00065 19.9 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORY05759.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain Zn-ribbon_8 PF09723.10 ORY05759.1 - 0.55 10.4 5.7 0.11 12.6 1.1 2.3 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 ORY05759.1 - 2.6 8.1 7.8 0.19 11.8 0.7 2.7 3 0 0 3 3 3 0 Double zinc ribbon Tyrosinase PF00264.20 ORY05760.1 - 1.3e-35 123.7 6.0 1.6e-34 120.2 6.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase zf-CCCH_2 PF14608.6 ORY05761.1 - 2.2e-35 119.9 84.4 3.3e-06 27.3 5.1 7.2 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 ORY05761.1 - 0.15 12.2 0.2 0.15 12.2 0.2 10.9 10 2 2 12 12 12 0 Zinc finger domain zf-CCCH_3 PF15663.5 ORY05761.1 - 9.5 6.5 23.6 14 5.9 0.9 4.2 2 2 1 3 3 3 0 Zinc-finger containing family PAP2_3 PF14378.6 ORY05763.1 - 3.2e-21 75.9 7.8 4.2e-21 75.5 7.8 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 ORY05763.1 - 7.4e-09 35.5 5.1 1.1e-08 34.9 5.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 ORY05763.1 - 0.24 12.0 3.8 0.61 10.7 3.8 1.6 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Aldo_ket_red PF00248.21 ORY05764.1 - 5.6e-24 84.9 0.0 5.8e-22 78.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family DUF2121 PF09894.9 ORY05764.1 - 0.0053 16.3 0.0 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) zf-met2 PF12907.7 ORY05765.1 - 1.9e-11 43.9 10.9 1.9e-11 43.9 10.9 2.5 2 1 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 ORY05765.1 - 5.4e-05 24.0 14.8 5.4e-05 24.0 14.8 1.6 2 0 0 2 2 2 1 4F5 protein family Xpo1 PF08389.12 ORY05766.1 - 4.4e-42 143.6 3.4 9.8e-42 142.5 0.4 3.0 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 ORY05766.1 - 3.5e-05 23.6 0.8 0.00015 21.6 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Fanconi_A_N PF15865.5 ORY05766.1 - 0.079 12.3 1.2 0.17 11.2 0.1 2.1 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus GATase_5 PF13507.6 ORY05767.1 - 1.8e-106 355.0 0.0 2.8e-106 354.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 ORY05767.1 - 4.2e-45 153.7 0.3 1.5e-29 103.2 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 ORY05767.1 - 2.3e-33 114.6 0.0 4.4e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 ORY05767.1 - 7.4e-23 80.8 0.0 1.6e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 ORY05767.1 - 0.1 13.3 2.6 4.5 8.0 0.0 3.5 4 0 0 4 4 4 0 AIR synthase related protein, N-terminal domain zf-C2H2 PF00096.26 ORY05768.1 - 2.6e-06 27.6 10.1 0.00037 20.8 2.3 3.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY05768.1 - 8.6e-06 26.0 0.4 0.00087 19.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY05768.1 - 3.3e-05 23.8 2.8 0.00071 19.5 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY05768.1 - 3.4e-05 24.1 19.1 0.00023 21.4 1.1 5.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY05768.1 - 6.6e-05 23.4 8.7 0.0011 19.7 1.3 4.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY05768.1 - 0.0002 21.5 2.9 0.0045 17.2 0.0 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ORY05768.1 - 0.08 13.0 1.7 4.4 7.4 0.0 2.5 1 1 1 2 2 2 0 BED zinc finger Peptidase_M20 PF01546.28 ORY05771.1 - 2.6e-13 50.1 0.0 4.5e-08 33.1 0.0 2.6 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY05771.1 - 3e-09 36.8 0.1 7.3e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY05771.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M28 E1-E2_ATPase PF00122.20 ORY05772.1 - 6.2e-51 172.5 4.3 6.2e-51 172.5 4.3 3.7 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORY05772.1 - 4.4e-23 82.7 0.1 1.7e-22 80.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY05772.1 - 7.6e-13 48.0 0.0 2.3e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 ORY05772.1 - 0.00028 20.6 11.9 0.00028 20.6 11.9 2.9 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 ORY05772.1 - 0.042 13.6 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ODV-E18 PF10717.9 ORY05772.1 - 0.092 12.6 1.3 1.7 8.6 0.5 2.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 HAD PF12710.7 ORY05772.1 - 0.11 12.9 0.3 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2818 PF10993.8 ORY05772.1 - 7.2 7.3 10.8 0.12 13.0 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2818) E1-E2_ATPase PF00122.20 ORY05773.1 - 9e-50 168.7 5.3 9e-50 168.7 5.3 3.8 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ORY05773.1 - 2.6e-21 76.9 0.1 7.1e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY05773.1 - 1e-13 50.8 0.2 4.5e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY05773.1 - 0.042 13.6 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORY05773.1 - 0.24 11.1 28.1 0.016 14.9 13.8 3.1 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus ODV-E18 PF10717.9 ORY05773.1 - 0.44 10.5 3.5 0.56 10.1 1.0 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Use1 PF09753.9 ORY05774.1 - 4.4e-45 154.3 13.3 1.2e-44 152.9 13.3 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Arc_PepC_II PF06847.11 ORY05774.1 - 0.058 13.9 1.2 0.19 12.3 0.1 2.4 2 2 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Synaptobrevin PF00957.21 ORY05774.1 - 0.071 12.9 0.3 0.38 10.6 0.3 2.2 1 1 0 1 1 1 0 Synaptobrevin DUF2207 PF09972.9 ORY05774.1 - 0.1 11.3 0.4 0.16 10.7 0.3 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) GP41 PF00517.17 ORY05774.1 - 0.31 10.9 2.7 17 5.3 0.4 2.9 3 0 0 3 3 3 0 Retroviral envelope protein TBCA PF02970.16 ORY05774.1 - 2.4 8.5 7.0 0.84 10.0 0.2 2.9 3 0 0 3 3 3 0 Tubulin binding cofactor A Spectrin PF00435.21 ORY05774.1 - 2.5 8.6 10.2 2.7 8.5 0.2 3.3 2 2 1 3 3 3 0 Spectrin repeat Glyco_hydro_46 PF01374.18 ORY05775.1 - 3.2e-34 118.4 0.0 3.8e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Polyketide_cyc PF03364.20 ORY05775.1 - 0.037 14.2 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport tRNA-synt_1c PF00749.21 ORY05776.1 - 4.6e-111 370.7 0.1 4.6e-111 370.7 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY05776.1 - 4.7e-38 130.8 0.4 1.2e-37 129.5 0.4 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 ORY05776.1 - 0.0029 17.8 0.1 0.0029 17.8 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 ORY05776.1 - 0.013 14.9 0.2 0.026 13.9 0.2 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.6 ORY05776.1 - 0.058 13.6 0.1 0.058 13.6 0.1 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY05776.1 - 0.093 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF3872 PF12988.7 ORY05776.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Dicty_CAR PF05462.11 ORY05777.1 - 0.18 10.9 16.1 0.02 14.0 11.2 1.8 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor Col_cuticle_N PF01484.17 ORY05777.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.5 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Myb_DNA-bind_2 PF08914.11 ORY05778.1 - 1.6e-19 69.8 0.4 7.4e-19 67.7 0.2 2.2 2 0 0 2 2 2 1 Rap1 Myb domain BRCT_2 PF16589.5 ORY05778.1 - 1.2e-12 48.0 0.1 3.3e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1_C PF11626.8 ORY05778.1 - 3.1e-07 30.4 0.2 0.00056 19.9 0.0 3.1 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.10 ORY05778.1 - 4e-05 24.2 0.3 4e-05 24.2 0.3 2.9 3 1 0 3 3 3 1 Rap1, DNA-binding N-glycanase_C PF09113.10 ORY05778.1 - 0.022 14.5 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Myb_DNA-bind_5 PF13873.6 ORY05778.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Arf PF00025.21 ORY05779.1 - 1.6e-78 262.2 0.1 1.8e-78 262.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY05779.1 - 5.5e-16 58.9 0.1 7.3e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY05779.1 - 6.7e-14 51.8 0.0 7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY05779.1 - 1.4e-12 47.4 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORY05779.1 - 1.8e-12 47.1 1.4 5.4e-08 32.4 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY05779.1 - 3.4e-10 39.7 0.0 4.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY05779.1 - 0.00011 22.2 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY05779.1 - 0.0016 17.8 0.4 0.0023 17.3 0.1 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Abhydrolase_1 PF00561.20 ORY05780.1 - 1.5e-49 168.9 0.0 1.2e-48 166.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY05780.1 - 4.3e-05 23.3 0.0 7.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORY05780.1 - 0.022 14.0 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 ORY05780.1 - 0.1 11.9 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Pribosyltran PF00156.27 ORY05781.1 - 0.00012 21.6 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MCU PF04678.13 ORY05782.1 - 3.5e-34 118.4 0.5 4.6e-34 118.0 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter MIP PF00230.20 ORY05783.1 - 9e-57 192.4 10.7 1.1e-56 192.1 10.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein HPP PF04982.13 ORY05783.1 - 0.34 11.1 7.8 0.087 13.0 0.5 2.6 2 2 0 2 2 2 0 HPP family DUF1772 PF08592.11 ORY05783.1 - 1.9 8.8 8.5 0.27 11.5 3.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) Polyketide_cyc2 PF10604.9 ORY05784.1 - 2.6e-05 24.5 0.0 4.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ORY05785.1 - 0.018 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ORY05786.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FeS_assembly_P PF01883.19 ORY05787.1 - 2.2e-15 56.6 0.1 4.1e-15 55.7 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Pkinase PF00069.25 ORY05788.1 - 9.7e-70 234.9 0.0 1.1e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05788.1 - 2.9e-40 138.2 0.0 3.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY05788.1 - 2.4e-06 27.1 0.0 9e-06 25.2 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY05788.1 - 4.8e-06 26.1 0.1 7.2e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY05788.1 - 0.00021 21.3 0.0 0.0074 16.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY05788.1 - 0.00026 20.0 0.1 0.00039 19.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY05788.1 - 0.003 16.4 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 ORY05788.1 - 0.097 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Lipase_3 PF01764.25 ORY05789.1 - 1.2e-23 83.5 0.1 2.1e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORY05789.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 ORY05789.1 - 0.0073 15.8 0.4 0.011 15.2 0.3 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY05789.1 - 0.045 14.4 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY05789.1 - 0.051 12.8 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cutinase PF01083.22 ORY05789.1 - 0.08 12.9 0.6 0.29 11.1 0.6 1.8 1 1 0 1 1 1 0 Cutinase PGAP1 PF07819.13 ORY05789.1 - 0.13 11.9 0.8 0.28 10.9 0.7 1.6 1 1 0 1 1 1 0 PGAP1-like protein CCDC84 PF14968.6 ORY05841.1 - 4.7e-58 197.5 6.7 6.3e-58 197.1 6.7 1.2 1 0 0 1 1 1 1 Coiled coil protein 84 FbpA PF05833.11 ORY05841.1 - 0.0034 16.2 4.2 0.0051 15.6 4.2 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) CHASE9 PF17153.4 ORY05841.1 - 0.076 13.2 2.1 0.19 11.9 2.1 1.6 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular DIRP PF06584.13 ORY05841.1 - 0.11 12.7 1.9 0.23 11.6 1.9 1.5 1 0 0 1 1 1 0 DIRP zf-DBF PF07535.12 ORY05841.1 - 0.49 10.6 5.2 0.16 12.1 0.6 2.3 2 0 0 2 2 2 0 DBF zinc finger CAMSAP_CC1 PF17095.5 ORY05841.1 - 3.7 7.5 10.9 8.8 6.3 10.9 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin OmpH PF03938.14 ORY05841.1 - 4.6 7.6 12.3 11 6.3 12.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Methyltr_RsmB-F PF01189.17 ORY05842.1 - 8.1e-38 130.1 0.0 6.5e-37 127.1 0.0 2.4 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY05842.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4517 PF15006.6 ORY05842.1 - 0.15 12.2 1.0 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4517) HLH PF00010.26 ORY05843.1 - 1.5e-19 69.7 0.3 1.5e-19 69.7 0.3 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain MCM2_N PF12619.8 ORY05843.1 - 0.027 14.8 0.7 0.084 13.2 0.7 1.8 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Asp2 PF16929.5 ORY05843.1 - 0.032 13.2 3.0 0.051 12.5 3.0 1.3 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter V-SNARE PF05008.15 ORY05844.1 - 4e-22 78.4 0.6 1.2e-21 76.9 0.6 1.8 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORY05844.1 - 1.1e-17 64.0 4.0 1.1e-17 64.0 4.0 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY05844.1 - 0.0072 16.2 1.3 0.014 15.3 0.2 2.1 2 2 0 2 2 2 1 Sec20 SNARE PF05739.19 ORY05844.1 - 0.016 15.2 0.5 0.039 14.0 0.5 1.7 1 0 0 1 1 1 0 SNARE domain DUF2730 PF10805.8 ORY05844.1 - 0.033 14.3 1.0 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 ORY05844.1 - 0.32 10.5 5.2 0.93 9.0 5.2 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ribonuc_red_sm PF00268.21 ORY05845.1 - 4e-122 407.1 0.2 4.7e-122 406.8 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Homeodomain PF00046.29 ORY05846.1 - 3.5e-19 68.4 2.6 7.8e-19 67.3 2.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY05846.1 - 0.14 12.1 1.9 0.23 11.4 0.2 2.2 2 0 0 2 2 2 0 Homeobox KN domain S-AdoMet_synt_C PF02773.16 ORY05847.1 - 5.1e-68 227.3 0.0 1.1e-67 226.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORY05847.1 - 1.6e-47 160.7 0.0 3.2e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORY05847.1 - 9e-46 154.6 0.2 1.9e-45 153.6 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORY05847.1 - 0.028 13.2 1.0 0.14 10.9 0.2 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) GIDA PF01134.22 ORY05848.1 - 2.2e-159 530.8 0.0 2.7e-159 530.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 ORY05848.1 - 3.1e-68 230.1 0.0 4.9e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 ORY05848.1 - 3.1e-06 26.6 1.0 3.1e-05 23.4 1.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY05848.1 - 5.1e-06 26.1 0.1 1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY05848.1 - 1.1e-05 24.7 1.5 0.00023 20.4 1.0 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORY05848.1 - 0.0018 17.1 2.5 0.03 13.0 0.3 2.9 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY05848.1 - 0.0035 16.7 0.1 0.008 15.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORY05848.1 - 0.11 11.7 0.2 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Septin PF00735.18 ORY05849.1 - 4.1e-109 364.2 0.0 5.1e-109 363.9 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY05849.1 - 9.9e-06 25.6 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY05849.1 - 2.5e-05 24.4 0.1 0.11 12.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORY05849.1 - 0.0037 17.2 0.3 0.052 13.5 0.2 2.6 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORY05849.1 - 0.0042 16.4 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 ORY05849.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1295 PF06966.12 ORY05850.1 - 2.3e-60 204.1 4.1 2.8e-60 203.7 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ORY05850.1 - 2.3e-05 24.4 1.0 2.3e-05 24.4 1.0 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 ORY05850.1 - 0.0001 22.6 0.3 0.0017 18.7 0.3 3.0 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 ORY05850.1 - 0.0032 17.9 0.1 0.013 15.9 0.0 2.1 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family G-gamma PF00631.22 ORY05851.1 - 1.1e-18 66.9 0.1 1.2e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 GGL domain IQ PF00612.27 ORY05852.1 - 0.026 14.3 0.5 0.026 14.3 0.5 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif IQ PF00612.27 ORY05853.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.6 3 1 1 4 4 4 0 IQ calmodulin-binding motif Metallophos PF00149.28 ORY05854.1 - 3.7e-16 60.2 0.1 4.8e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY05854.1 - 6.1e-08 33.0 0.0 9.8e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 ORY05854.1 - 0.0064 15.9 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Sarcoglycan_1 PF04790.13 ORY05854.1 - 0.65 9.3 1.9 1.1 8.6 1.9 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein zf-U11-48K PF05253.12 ORY05856.1 - 3.5e-06 26.8 1.8 1e-05 25.3 1.8 1.9 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger EBP PF05241.12 ORY05857.1 - 8.1e-45 152.4 9.2 9.2e-45 152.3 9.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein PIG-Y PF15159.6 ORY05858.1 - 1.6e-20 73.8 12.3 1.8e-20 73.6 12.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Transketolase_N PF00456.21 ORY05859.1 - 8.1e-154 511.5 0.0 1e-153 511.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY05859.1 - 1.3e-45 155.2 0.0 2.8e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY05859.1 - 8.7e-14 51.5 0.0 4.4e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY05859.1 - 9.6e-05 21.7 0.0 0.00035 19.9 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORY05859.1 - 0.0018 17.3 0.1 0.0032 16.4 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.21 ORY05859.1 - 0.002 17.9 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain TPP_enzyme_C PF02775.21 ORY05859.1 - 0.0022 17.8 0.7 0.058 13.2 0.7 2.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ion_trans PF00520.31 ORY05860.1 - 2.9e-150 498.3 87.0 1.4e-45 155.5 13.9 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 ORY05860.1 - 7.5e-05 21.6 78.4 0.0052 15.5 12.0 8.5 6 4 2 8 8 8 6 Polycystin cation channel GPHH PF16905.5 ORY05860.1 - 0.014 15.2 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated DNA_ligase_A_M PF01068.21 ORY05861.1 - 2.9e-12 46.7 0.4 4.1e-12 46.2 0.4 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 ORY05861.1 - 4.6e-09 36.2 0.0 9.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain RNA_ligase PF09414.10 ORY05861.1 - 0.0032 17.8 0.1 0.0045 17.3 0.1 1.2 1 0 0 1 1 1 1 RNA ligase Ofd1_CTDD PF10637.9 ORY05862.1 - 5.2e-37 127.6 1.0 8.8e-31 107.2 0.3 3.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY05862.1 - 2.3e-31 108.3 0.2 2.6e-25 88.9 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY05862.1 - 5.9e-19 68.7 0.0 3e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 ORY05862.1 - 0.017 15.6 0.0 0.044 14.3 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Raptor_N PF14538.6 ORY05862.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Cullin PF00888.22 ORY05863.1 - 3.6e-196 653.5 14.0 3.6e-196 653.5 14.0 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 ORY05863.1 - 1.2e-26 92.5 6.9 2.6e-26 91.5 5.4 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2150 PF09920.9 ORY05863.1 - 0.0093 16.0 0.2 0.056 13.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2150) AnfG_VnfG PF03139.15 ORY05863.1 - 1.5 8.9 7.1 0.17 12.0 0.5 2.7 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit Penicillinase_R PF03965.16 ORY05863.1 - 3.5 8.0 9.0 1.3 9.4 0.6 3.7 4 0 0 4 4 4 0 Penicillinase repressor PH PF00169.29 ORY05864.1 - 7.9e-08 32.8 1.6 7.9e-08 32.8 1.6 1.8 2 0 0 2 2 2 1 PH domain EHN PF06441.12 ORY05865.1 - 1.1e-30 106.2 0.2 2.2e-30 105.2 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY05865.1 - 5.5e-18 65.5 0.1 8.7e-18 64.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY05865.1 - 0.048 14.3 2.2 0.7 10.5 2.2 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Polysacc_deac_1 PF01522.21 ORY05866.1 - 1.5e-33 115.3 0.0 2.1e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY05866.1 - 0.00092 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Abhydrolase_3 PF07859.13 ORY05867.1 - 1.1e-23 84.2 0.0 2.6e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY05867.1 - 1.3e-09 37.8 0.0 4.3e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ORY05867.1 - 1.7e-08 33.8 0.1 4e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ORY05867.1 - 3.9e-07 29.9 0.0 8.6e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ORY05867.1 - 9.8e-06 25.5 0.0 0.026 14.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 ORY05867.1 - 0.00019 20.2 0.0 0.00067 18.4 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ORY05867.1 - 0.00071 19.6 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ORY05867.1 - 0.001 19.7 0.0 0.0028 18.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ORY05867.1 - 0.0022 16.9 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORY05867.1 - 0.047 12.9 0.0 0.13 11.5 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 LIP PF03583.14 ORY05867.1 - 0.06 12.7 0.1 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_1 PF00561.20 ORY05867.1 - 0.17 11.5 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Calmodulin_bind PF07887.11 ORY05867.1 - 0.21 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Calmodulin binding protein-like VHS PF00790.19 ORY05869.1 - 6.7e-23 81.1 0.4 1.7e-22 79.8 0.0 1.9 2 1 0 2 2 2 1 VHS domain GAT PF03127.14 ORY05869.1 - 2.2e-13 50.3 2.1 2.2e-13 50.3 2.1 2.0 2 0 0 2 2 2 1 GAT domain DHquinase_I PF01487.15 ORY05869.1 - 0.012 15.9 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Type I 3-dehydroquinase She9_MDM33 PF05546.11 ORY05869.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 She9 / Mdm33 family RhoGAP PF00620.27 ORY05870.1 - 2.3e-47 160.7 0.0 4.7e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY05870.1 - 7.8e-07 29.6 0.0 1.9e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 ORY05870.1 - 5.8e-06 26.7 0.4 1.5e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain RasGEF PF00617.19 ORY05870.1 - 2.9e-05 24.4 0.9 0.42 10.8 0.4 3.1 3 0 0 3 3 3 2 RasGEF domain CENP-F_N PF10481.9 ORY05870.1 - 0.28 10.8 6.1 0.24 11.0 4.5 1.7 2 0 0 2 2 2 0 Cenp-F N-terminal domain Tyrosinase PF00264.20 ORY05871.1 - 6.6e-16 59.3 0.3 5.2e-09 36.7 0.1 2.1 1 1 1 2 2 2 2 Common central domain of tyrosinase She2p PF11435.8 ORY05871.1 - 0.064 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding protein She2p Ras PF00071.22 ORY05872.1 - 5.5e-47 159.4 0.1 6.7e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY05872.1 - 2.3e-15 56.9 0.0 6.9e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY05872.1 - 7.7e-11 41.7 0.0 8.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY05872.1 - 6e-05 22.7 0.1 0.00012 21.7 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY05872.1 - 0.0023 17.9 0.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 ORY05872.1 - 0.0033 17.4 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PglD_N PF17836.1 ORY05872.1 - 0.045 14.4 0.1 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 PglD N-terminal domain AAA_22 PF13401.6 ORY05872.1 - 0.12 12.6 0.4 1.6 9.0 0.1 2.5 1 1 1 2 2 2 0 AAA domain Ribosomal_S14 PF00253.21 ORY05873.1 - 1e-15 57.2 4.8 1.1e-15 57.1 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ORY05873.1 - 0.032 14.2 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Abhydrolase_2 PF02230.16 ORY05874.1 - 1.1e-20 74.4 0.0 1.5e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORY05874.1 - 6.2e-06 26.0 0.1 8.3e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 ORY05874.1 - 4.8e-05 23.4 2.9 0.2 11.6 0.4 3.1 1 1 2 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ORY05874.1 - 0.00011 21.5 0.1 0.68 9.1 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY05874.1 - 0.00015 21.3 0.0 0.0003 20.4 0.0 1.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY05874.1 - 0.00056 19.6 0.3 0.3 10.7 0.1 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.18 ORY05874.1 - 0.00087 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY05874.1 - 0.0013 19.4 0.0 0.018 15.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 ORY05874.1 - 0.0038 17.1 0.0 0.85 9.4 0.0 2.1 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Esterase PF00756.20 ORY05874.1 - 0.11 12.2 0.1 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Cutinase PF01083.22 ORY05874.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_4 PF08386.10 ORY05874.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 1 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 ORY05874.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase Rtt106 PF08512.12 ORY05875.1 - 9.6e-25 86.8 0.0 2.1e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like WD40 PF00400.32 ORY05876.1 - 9e-13 48.5 7.0 3.2e-06 27.8 0.4 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORY05876.1 - 4.8e-08 32.5 12.1 4.8e-08 32.5 12.1 2.9 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type BBS2_Mid PF14783.6 ORY05876.1 - 0.0037 17.3 0.1 0.64 10.1 0.0 2.6 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 ORY05876.1 - 0.013 15.8 2.0 1.8 8.9 0.1 3.8 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Rep_fac-A_C PF08646.10 ORY05876.1 - 0.014 15.1 5.6 0.035 13.9 5.6 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain Rhodanese_C PF12368.8 ORY05876.1 - 2.3 8.6 7.5 6.9 7.1 7.5 1.8 1 0 0 1 1 1 0 Rhodanase C-terminal zinc_ribbon_16 PF17034.5 ORY05876.1 - 4 7.7 16.1 1.4e+02 2.7 15.9 2.8 1 1 0 1 1 1 0 Zinc-ribbon like family F1F0-ATPsyn_F PF10791.9 ORY05877.1 - 1.6e-17 63.7 0.0 1.9e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi RRM_1 PF00076.22 ORY05878.1 - 3.7e-12 45.9 0.0 5.1e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_2 PF07653.17 ORY05879.1 - 0.023 14.3 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 ORY05879.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Band_7 PF01145.25 ORY05880.1 - 8.8e-24 84.5 7.2 1.1e-23 84.2 5.1 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 ORY05880.1 - 0.00046 19.3 3.1 0.0006 19.0 3.1 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial SH3_9 PF14604.6 ORY05881.1 - 7.1e-08 32.2 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY05881.1 - 1.7e-06 27.5 0.0 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY05881.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3042 PF11240.8 ORY05881.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Mad3_BUB1_I PF08311.12 ORY05882.1 - 1.6e-21 76.5 0.0 4.5e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 ORY05882.1 - 4.6e-19 68.8 0.0 1.4e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY05882.1 - 2.1e-05 24.0 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 ORY05882.1 - 0.00055 20.1 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 ORY05882.1 - 0.028 13.7 1.7 0.52 9.6 0.2 3.0 3 1 1 4 4 4 0 Kinase-like HATPase_c PF02518.26 ORY05884.1 - 5e-28 97.8 0.2 1.1e-27 96.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY05884.1 - 5.3e-19 68.5 0.4 1.2e-15 57.7 0.3 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 ORY05884.1 - 2e-15 56.5 0.0 4.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CBM9_1 PF06452.11 ORY05885.1 - 3.7e-13 49.8 0.7 1.1e-12 48.3 0.7 1.7 2 0 0 2 2 2 1 Carbohydrate family 9 binding domain-like Pilin_GH PF16734.5 ORY05885.1 - 0.053 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative Asp PF00026.23 ORY05886.1 - 5.5e-109 364.4 0.0 6.7e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY05886.1 - 6.2e-14 52.6 0.2 3.7e-11 43.6 0.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY05886.1 - 1.9e-07 31.0 0.0 4.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY05886.1 - 0.0054 17.4 0.1 4.6 7.9 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY05886.1 - 0.033 14.8 0.0 13 6.4 0.0 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease LRR_4 PF12799.7 ORY05887.1 - 3.1e-05 24.2 10.3 1.9 9.0 0.1 7.3 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) FSH1 PF03959.13 ORY05888.1 - 2.8e-54 184.0 0.0 3.2e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY05888.1 - 0.027 14.3 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PE-PPE PF08237.11 ORY05888.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain Cyt-b5 PF00173.28 ORY05889.1 - 2.5e-26 91.6 0.0 3.2e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cation_ATPase_C PF00689.21 ORY05891.1 - 2.6e-42 144.6 15.5 2.6e-42 144.6 15.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY05891.1 - 4.9e-34 117.4 1.7 4.9e-34 117.4 1.7 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY05891.1 - 4.9e-20 71.4 0.0 9.5e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY05891.1 - 2.5e-17 63.9 0.0 1.2e-16 61.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY05891.1 - 1.4e-11 43.9 0.4 9.4e-10 38.0 0.1 2.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY05891.1 - 2.5e-05 24.2 0.5 0.0029 17.4 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Integrase_1 PF12835.7 ORY05891.1 - 0.088 12.9 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Integrase Ferlin_C PF16165.5 ORY05891.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.5 2 1 1 3 3 3 0 Ferlin C-terminus CLASP_N PF12348.8 ORY05948.1 - 4.6e-29 101.6 3.3 9e-08 32.0 0.0 7.0 7 2 0 7 7 7 3 CLASP N terminal HEAT PF02985.22 ORY05948.1 - 1.3e-18 65.5 11.8 0.0034 17.5 0.0 10.4 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 ORY05948.1 - 4e-11 43.1 9.6 0.16 12.4 0.0 9.2 9 1 2 11 11 11 3 HEAT repeats Cnd1 PF12717.7 ORY05948.1 - 2.7e-10 40.6 11.5 0.16 12.0 0.0 9.0 8 2 0 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY05948.1 - 3.6e-10 40.3 0.1 0.47 11.1 0.0 7.4 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 ORY05948.1 - 9.7e-07 29.0 10.7 0.25 11.5 0.0 7.2 7 0 0 7 7 7 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 ORY05948.1 - 1e-06 29.1 5.3 0.51 10.9 0.0 7.0 8 0 0 8 8 8 2 HEAT-like repeat RTP1_C1 PF10363.9 ORY05948.1 - 2.8e-06 27.5 0.4 8.4 6.6 0.0 6.8 5 1 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 ORY05948.1 - 0.0098 16.2 0.0 0.34 11.3 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 ORY05948.1 - 0.018 13.6 11.7 1.9 6.9 0.0 6.1 8 0 0 8 8 8 0 Adaptin N terminal region DCB PF16213.5 ORY05948.1 - 0.023 14.4 2.2 1.1 8.9 0.0 3.5 4 0 0 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 VHS PF00790.19 ORY05948.1 - 0.038 13.8 1.6 9.5 6.1 0.0 3.9 4 0 0 4 4 4 0 VHS domain Ipi1_N PF12333.8 ORY05948.1 - 0.13 12.9 0.0 78 3.9 0.0 3.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation MFS_1 PF07690.16 ORY05949.1 - 6.5e-35 120.7 49.7 6.5e-35 120.7 49.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY05949.1 - 7.2e-06 25.1 26.6 0.0022 16.9 26.5 2.4 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 ORY05949.1 - 1.2e-05 24.4 42.0 0.00036 19.5 7.5 4.1 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_4 PF06779.14 ORY05949.1 - 0.00029 20.2 19.9 0.00029 20.2 19.9 2.1 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DEAD PF00270.29 ORY05950.1 - 9.8e-16 58.0 0.0 1.2e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY05950.1 - 2.4e-06 27.6 0.0 2.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 ORY05951.1 - 2.5e-21 76.0 0.4 5.4e-21 74.9 0.6 1.5 2 0 0 2 2 2 1 Sec63 Brl domain HHH_5 PF14520.6 ORY05951.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DnaJ PF00226.31 ORY05952.1 - 4.1e-21 74.9 0.8 4.1e-21 74.9 0.8 2.6 3 0 0 3 3 3 1 DnaJ domain Lysozyme_like PF13702.6 ORY05952.1 - 0.0051 16.5 0.5 0.23 11.1 0.1 2.3 2 0 0 2 2 2 1 Lysozyme-like Death PF00531.22 ORY05952.1 - 0.0058 16.8 1.5 2.1 8.6 0.0 2.8 3 1 0 3 3 3 2 Death domain DUF4839 PF16127.5 ORY05952.1 - 0.088 12.9 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4839) Csm1 PF12539.8 ORY05953.1 - 7.8e-14 52.1 0.0 1.5e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 ORY05953.1 - 3e-06 27.4 6.4 3e-06 27.4 6.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5094) End3 PF12761.7 ORY05953.1 - 0.0063 16.7 11.0 0.0063 16.7 11.0 1.7 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 FAM184 PF15665.5 ORY05953.1 - 0.018 14.8 10.8 0.032 14.0 10.8 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF5344 PF17279.2 ORY05953.1 - 0.061 13.9 0.1 0.061 13.9 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5344) Bap31_Bap29_C PF18035.1 ORY05953.1 - 0.088 12.8 11.6 0.18 11.8 6.4 2.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain K-box PF01486.17 ORY05953.1 - 0.11 12.7 9.5 0.1 12.8 3.3 2.9 2 1 1 3 3 3 0 K-box region DUF4618 PF15397.6 ORY05953.1 - 0.18 11.2 10.6 0.3 10.4 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Csm1_N PF18504.1 ORY05953.1 - 0.42 11.0 10.3 2.5 8.5 10.3 2.3 1 1 0 1 1 1 0 Csm1 N-terminal domain DUF1043 PF06295.12 ORY05953.1 - 0.43 10.6 9.3 1.2 9.2 9.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) HR1 PF02185.16 ORY05953.1 - 0.72 10.0 10.9 0.77 9.9 0.9 2.7 2 0 0 2 2 2 0 Hr1 repeat LPP PF04728.13 ORY05953.1 - 1.1 9.7 6.7 7.9 7.0 1.4 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF16 PF01519.16 ORY05953.1 - 1.6 9.2 10.1 6.1 7.4 10.1 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 FemAB PF02388.16 ORY05953.1 - 1.7 7.4 8.7 2.6 6.8 8.7 1.2 1 0 0 1 1 1 0 FemAB family Spc24 PF08286.11 ORY05953.1 - 2.3 8.5 11.7 1.4 9.2 7.3 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 ORY05953.1 - 3.7 7.6 16.1 2.8 8.0 9.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 ORY05953.1 - 4.3 6.5 6.1 6.2 6.0 6.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 ORY05953.1 - 7.9 5.7 17.4 0.2 11.0 8.9 2.0 2 0 0 2 2 2 0 FAM76 protein Malate_synthase PF01274.22 ORY05954.1 - 7.4e-225 747.2 0.0 8.4e-225 747.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase WD40 PF00400.32 ORY05955.1 - 5e-37 125.3 19.9 4.9e-09 36.7 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY05955.1 - 1.5e-17 63.7 7.2 0.00037 20.7 0.2 5.9 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY05955.1 - 1.3e-07 31.7 3.8 0.002 18.1 0.2 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY05955.1 - 0.01 14.8 0.2 0.27 10.1 0.1 2.6 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 ORY05955.1 - 0.26 9.2 1.2 1.3 6.9 0.1 2.3 1 1 0 2 2 2 0 IKI3 family Malate_synthase PF01274.22 ORY05956.1 - 6.5e-225 747.4 0.0 7.3e-225 747.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.22 ORY05957.1 - 6.9e-220 730.8 0.0 7.6e-220 730.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.22 ORY05958.1 - 1.7e-210 699.7 0.0 1.1e-209 697.2 0.0 1.8 1 1 0 1 1 1 1 Malate synthase CDP-OH_P_transf PF01066.21 ORY05959.1 - 1.3e-12 48.3 0.6 1.3e-12 48.3 0.6 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TFIIB PF00382.19 ORY05960.1 - 4.9e-46 154.6 0.2 2.5e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY05960.1 - 2.9e-15 55.5 1.2 5.1e-15 54.7 1.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 ORY05960.1 - 4.1e-05 23.6 0.0 0.067 13.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 ORY05960.1 - 0.00073 19.3 0.1 0.062 13.0 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Guanylin PF02058.15 ORY05960.1 - 0.022 15.2 0.7 5.3 7.6 0.3 3.1 1 1 2 3 3 3 0 Guanylin precursor Sigma70_r4_2 PF08281.12 ORY05960.1 - 0.057 13.1 0.6 0.48 10.2 0.0 2.8 4 0 0 4 4 4 0 Sigma-70, region 4 TMIE PF16038.5 ORY05960.1 - 0.071 13.0 1.1 0.2 11.5 0.8 1.8 2 0 0 2 2 2 0 TMIE protein RB_B PF01857.20 ORY05960.1 - 0.19 11.8 0.2 0.46 10.5 0.0 1.6 2 1 0 2 2 2 0 Retinoblastoma-associated protein B domain MSC PF09402.10 ORY05961.1 - 8e-73 245.8 0.1 1.1e-72 245.4 0.1 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORY05961.1 - 4.2e-12 45.6 0.0 4.2e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 HeH/LEM domain UPF0183 PF03676.14 ORY05962.1 - 1.5e-76 258.2 2.1 5.2e-76 256.5 0.7 2.1 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0183) RhoGAP PF00620.27 ORY05963.1 - 7.3e-38 129.8 0.0 1.1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain IstB_IS21_ATP PF08483.11 ORY05963.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal MIF4G PF02854.19 ORY05964.1 - 9.6e-57 192.0 3.7 9.6e-57 192.0 3.7 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 ORY05964.1 - 7.4e-16 58.1 1.3 1.3e-15 57.3 0.1 2.0 2 0 0 2 2 2 1 MA3 domain eIF_4G1 PF12152.8 ORY05964.1 - 8.8e-10 38.6 0.3 8.8e-10 38.6 0.3 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4G1 FANCI_S2 PF14676.6 ORY05964.1 - 0.17 12.2 3.1 16 5.8 0.1 3.2 3 0 0 3 3 3 0 FANCI solenoid 2 PB1 PF00564.24 ORY05965.1 - 3.2e-13 49.4 0.9 5.7e-13 48.6 0.9 1.4 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 ORY05965.1 - 8.5e-12 44.4 4.6 0.00078 19.2 0.0 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY05965.1 - 1.9e-08 33.8 6.6 0.19 11.9 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY05965.1 - 6.9e-08 32.1 2.4 0.037 14.2 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY05965.1 - 2.6e-05 24.4 0.5 0.0055 17.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY05965.1 - 0.062 13.4 1.5 0.38 10.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY05965.1 - 0.076 13.7 3.3 27 5.7 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY05965.1 - 0.084 12.6 0.6 0.51 10.1 0.1 2.7 2 1 1 3 3 3 0 TPR repeat TPR_17 PF13431.6 ORY05965.1 - 0.088 13.2 2.1 62 4.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY05965.1 - 0.17 12.6 1.6 3.9 8.2 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 ORY05966.1 - 3.1e-44 151.5 0.4 4e-42 144.6 0.3 2.6 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 ORY05966.1 - 3.2e-24 85.7 2.4 3e-12 46.1 0.3 3.5 1 1 1 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 ORY05966.1 - 0.00039 20.4 0.0 0.00098 19.1 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 ORY05966.1 - 0.0056 16.9 0.2 0.035 14.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY05966.1 - 0.029 15.0 0.5 0.43 11.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 ORY05966.1 - 0.032 13.2 0.3 0.052 12.5 0.3 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 ORY05966.1 - 0.15 12.3 1.4 0.46 10.7 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY05966.1 - 0.69 9.8 2.3 1.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Med14 PF08638.11 ORY05967.1 - 7e-63 211.5 0.3 1.8e-62 210.2 0.3 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 TonB_N PF16031.5 ORY05967.1 - 1.5 9.4 10.9 10 6.6 0.1 2.6 2 0 0 2 2 2 0 TonB polyproline region Pterin_bind PF00809.22 ORY05968.1 - 8.9e-86 287.5 0.0 1.4e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 ORY05968.1 - 3.6e-53 178.8 0.4 2.3e-25 89.3 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 ORY05968.1 - 9.1e-38 129.2 0.0 4.4e-37 127.0 0.0 2.2 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) BTB PF00651.31 ORY05969.1 - 7.7e-08 32.6 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ERG4_ERG24 PF01222.17 ORY05970.1 - 3.3e-147 490.7 19.7 4e-147 490.5 19.7 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY05970.1 - 0.00017 21.2 0.5 0.00017 21.2 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PIG-F PF06699.11 ORY05970.1 - 0.017 15.3 0.5 0.051 13.7 0.5 1.8 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F DUF2070 PF09843.9 ORY05970.1 - 1.6 6.9 6.4 3.1 6.0 6.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ferrochelatase PF00762.19 ORY05971.1 - 1.6e-109 365.9 0.0 1.8e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 ORY05971.1 - 0.059 13.7 0.0 7.2 7.0 0.0 2.8 3 0 0 3 3 3 0 CbiX Integrase_H2C2 PF17921.1 ORY05972.1 - 5.4 7.2 5.6 70 3.6 2.7 2.7 2 1 0 2 2 2 0 Integrase zinc binding domain SSI PF00720.17 ORY05973.1 - 2.6e-18 65.8 0.0 3.2e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Subtilisin inhibitor-like NAS PF03059.16 ORY05974.1 - 1.1e-72 244.7 0.2 1.3e-72 244.5 0.2 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 ORY05974.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 ORY05974.1 - 0.032 13.5 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DUF3220 PF11516.8 ORY05974.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) CheR PF01739.18 ORY05974.1 - 0.091 12.2 0.0 0.3 10.5 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain MFS_1 PF07690.16 ORY05975.1 - 3.7e-31 108.3 11.6 3.7e-31 108.3 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY05975.1 - 4.9e-20 71.8 3.8 6e-20 71.5 0.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 ORY05975.1 - 2e-05 23.3 10.7 0.00027 19.6 1.5 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 ORY05975.1 - 2.1e-05 23.5 0.0 0.00035 19.5 0.0 2.8 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 ORY05975.1 - 0.00019 20.9 1.7 0.00019 20.9 1.7 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ORY05975.1 - 0.027 12.9 4.0 1.6 7.1 0.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2754 PF10953.8 ORY05975.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2754) OPT PF03169.15 ORY05976.1 - 6.2e-90 302.6 33.9 7.1e-90 302.4 33.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 ORY05976.1 - 0.15 12.3 1.1 0.64 10.3 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) WD40 PF00400.32 ORY05977.1 - 3.1e-50 167.1 23.2 2.7e-09 37.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY05977.1 - 5.2e-13 49.1 2.2 0.024 14.9 0.0 5.1 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY05977.1 - 3e-05 23.1 0.2 0.24 10.3 0.0 4.3 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY05977.1 - 0.00015 21.7 0.1 0.032 14.1 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY05977.1 - 0.003 16.3 8.2 0.039 12.6 0.1 4.7 4 2 1 6 6 6 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORY05977.1 - 0.0044 15.6 0.1 0.78 8.2 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 ORY05977.1 - 0.023 14.6 0.1 31 4.7 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 ORY05978.1 - 6.2e-23 81.7 0.1 1.9e-16 60.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY05978.1 - 4.5e-20 71.9 0.0 6.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY05978.1 - 8.4e-15 56.0 0.0 1e-14 55.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY05978.1 - 9.6e-07 28.6 0.0 0.00054 19.6 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORY05978.1 - 5.5e-05 22.9 0.0 0.00016 21.4 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 ORY05978.1 - 8.1e-05 22.4 0.1 0.00027 20.7 0.1 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 ORY05978.1 - 0.001 18.6 0.7 0.53 9.7 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 ORY05978.1 - 0.0094 15.9 0.1 0.33 10.8 0.1 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 ORY05978.1 - 0.016 15.3 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 ORY05978.1 - 0.019 14.7 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 ORY05978.1 - 0.03 14.2 0.2 0.071 13.0 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 ORY05978.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF2048 PF09752.9 ORY05978.1 - 0.22 10.6 0.4 0.3 10.1 0.4 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 RNA_pol_Rpb1_5 PF04998.17 ORY05979.1 - 5.6e-109 363.7 0.1 1.1e-108 362.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 ORY05979.1 - 1.3e-101 340.0 0.0 3.4e-101 338.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 ORY05979.1 - 1.4e-77 259.6 0.1 3.3e-77 258.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 ORY05979.1 - 8.6e-70 234.5 0.1 1.8e-69 233.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 ORY05979.1 - 3.3e-52 176.1 6.0 8.2e-52 174.8 6.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 ORY05979.1 - 4.8e-49 166.3 0.0 1.5e-48 164.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY05979.1 - 1.1e-36 125.0 0.1 2.8e-36 123.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 mRNA_triPase PF02940.15 ORY05980.1 - 1e-49 169.2 1.1 1.3e-49 168.9 1.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain MS_channel PF00924.18 ORY05980.1 - 0.2 11.2 0.3 0.38 10.2 0.1 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel UCR_hinge PF02320.16 ORY05981.1 - 1.4e-24 86.1 4.5 1.4e-24 86.1 4.5 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Euplotes_phero PF05842.11 ORY05981.1 - 0.027 15.0 0.6 0.032 14.8 0.6 1.1 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein TraF PF13728.6 ORY05981.1 - 0.093 12.5 0.3 0.12 12.2 0.3 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein RasGAP PF00616.19 ORY05981.1 - 0.59 9.8 2.7 2.4 7.8 1.1 1.9 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase PTPRCAP PF15713.5 ORY05981.1 - 1.8 8.8 10.4 2.1 8.6 10.4 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CBS PF00571.28 ORY05982.1 - 5.1e-24 84.5 4.9 5e-11 42.9 0.3 4.4 4 0 0 4 4 4 4 CBS domain bZIP_1 PF00170.21 ORY05983.1 - 1.3e-10 41.2 10.4 1.3e-10 41.2 10.4 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY05983.1 - 1.2e-06 28.5 11.1 1.9e-06 27.8 11.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY05983.1 - 0.054 14.0 10.3 0.097 13.2 10.2 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_S14 PF00253.21 ORY05984.1 - 3.8e-15 55.4 4.2 4.2e-15 55.2 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ORY05984.1 - 0.028 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Ribosomal_S7 PF00177.21 ORY05985.1 - 1e-37 129.0 0.8 1.3e-37 128.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PAS_3 PF08447.12 ORY05986.1 - 1.5e-16 60.4 0.0 3e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY05986.1 - 2.6e-08 34.1 0.0 7.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORY05986.1 - 8.6e-08 32.2 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORY05986.1 - 2.2e-06 27.9 0.0 0.0031 17.7 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.11 ORY05986.1 - 0.00011 22.9 0.0 0.011 16.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 ORY05986.1 - 0.012 15.7 0.0 0.081 13.1 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_12 PF18095.1 ORY05986.1 - 0.1 12.2 0.0 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Ribosomal_L37ae PF01780.19 ORY05987.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORY05987.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORY05987.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORY05987.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORY05987.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Nop PF01798.18 ORY05988.1 - 2.2e-85 285.8 0.3 2.2e-85 285.8 0.3 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORY05988.1 - 3.9e-22 78.4 0.7 3.9e-22 78.4 0.7 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 ORY05988.1 - 2.2 8.5 14.1 4 7.6 14.1 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 ORY05988.1 - 2.3 8.3 37.8 0.035 14.2 30.5 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 PDZ_1 PF12812.7 ORY05989.1 - 5e-49 164.2 0.0 3.8e-33 113.3 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORY05989.1 - 1e-22 81.6 0.9 6e-20 72.7 0.1 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ORY05989.1 - 1.6e-14 53.5 0.0 0.00062 19.6 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 ORY05989.1 - 6.9e-08 32.7 0.0 0.028 14.8 0.0 3.8 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 ORY05989.1 - 2.4e-07 31.0 0.0 0.053 13.8 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 ORY05989.1 - 0.013 15.4 0.1 0.86 9.6 0.0 3.4 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ORY05989.1 - 0.046 12.4 0.2 0.34 9.5 0.1 1.9 2 0 0 2 2 2 0 Peptidase S46 Trypsin PF00089.26 ORY05989.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Trypsin DUF31 PF01732.16 ORY05989.1 - 0.053 13.1 0.4 0.076 12.5 0.4 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Aminotran_1_2 PF00155.21 ORY05990.1 - 3.1e-39 135.2 0.0 4.5e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY05990.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AAA PF00004.29 ORY05991.1 - 6.7e-97 321.0 0.0 4.9e-47 159.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY05991.1 - 1.1e-26 92.3 7.2 1e-12 47.7 0.1 3.2 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 ORY05991.1 - 3.8e-20 71.8 0.4 2.1e-19 69.5 0.3 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ORY05991.1 - 3e-14 53.1 0.0 7.7e-06 25.7 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY05991.1 - 1.7e-13 51.0 0.0 1.7e-07 31.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 ORY05991.1 - 1.5e-12 47.1 0.0 3.1e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 ORY05991.1 - 9.7e-12 45.3 0.0 5.5e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY05991.1 - 3.3e-11 43.9 0.1 0.00045 20.6 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 ORY05991.1 - 5.9e-11 42.5 0.2 3.7e-05 23.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY05991.1 - 1.1e-08 35.4 0.4 0.061 13.6 0.0 4.1 3 2 0 3 3 2 2 AAA domain TIP49 PF06068.13 ORY05991.1 - 1.2e-08 34.6 0.1 0.0018 17.5 0.0 2.9 2 1 1 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 ORY05991.1 - 9.2e-08 32.4 0.0 0.0051 17.2 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 ORY05991.1 - 2e-07 30.6 0.2 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 ORY05991.1 - 2.1e-07 30.8 0.3 3.2e-06 27.0 0.1 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 ORY05991.1 - 4e-07 30.1 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY05991.1 - 5e-07 30.3 0.0 0.031 14.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ORY05991.1 - 9.5e-07 29.4 0.0 0.0068 16.9 0.0 3.9 3 1 0 3 3 2 1 ABC transporter IstB_IS21 PF01695.17 ORY05991.1 - 2e-06 27.7 0.0 0.062 13.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 ORY05991.1 - 9.6e-06 24.9 0.1 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 ORY05991.1 - 1.1e-05 25.0 0.0 0.064 12.8 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 ORY05991.1 - 1.2e-05 25.7 0.1 0.16 12.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain ATPase PF06745.13 ORY05991.1 - 1.2e-05 24.8 0.2 0.51 9.6 0.0 3.4 3 0 0 3 3 3 2 KaiC Bac_DnaA PF00308.18 ORY05991.1 - 1.8e-05 24.7 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_25 PF13481.6 ORY05991.1 - 2.8e-05 23.8 2.4 1.6 8.2 0.0 3.7 2 2 2 4 4 3 2 AAA domain AAA_24 PF13479.6 ORY05991.1 - 4e-05 23.4 0.0 0.12 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 ORY05991.1 - 4.7e-05 23.4 0.7 0.26 11.2 0.0 3.4 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea DUF815 PF05673.13 ORY05991.1 - 7.9e-05 21.9 0.0 0.039 13.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 ORY05991.1 - 8.5e-05 22.4 0.0 0.0065 16.2 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 ORY05991.1 - 9.4e-05 22.2 0.0 0.63 9.7 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 ORY05991.1 - 0.00011 22.6 1.9 0.55 10.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain TsaE PF02367.17 ORY05991.1 - 0.00013 21.9 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 ORY05991.1 - 0.00046 20.1 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 ORY05991.1 - 0.00069 19.1 0.2 1.1 8.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 ORY05991.1 - 0.00071 19.5 0.2 0.3 11.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 ORY05991.1 - 0.00072 18.9 0.0 0.52 9.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 ORY05991.1 - 0.00079 19.5 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 ORY05991.1 - 0.001 18.3 0.0 0.17 11.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.6 ORY05991.1 - 0.0013 18.6 0.5 1.4 8.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 ORY05991.1 - 0.0031 16.8 0.0 1.4 8.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORY05991.1 - 0.0091 16.3 0.7 13 6.1 0.0 3.5 3 1 1 4 4 3 0 AAA domain Rad17 PF03215.15 ORY05991.1 - 0.0092 15.9 0.0 0.88 9.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 ORY05991.1 - 0.0093 16.1 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 ORY05991.1 - 0.019 14.9 0.6 5 7.0 0.0 3.8 4 0 0 4 4 4 0 NTPase AAA_30 PF13604.6 ORY05991.1 - 0.019 14.7 0.1 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 ORY05991.1 - 0.031 14.4 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.12 ORY05991.1 - 0.16 11.6 0.0 2.3 7.8 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 ORY05991.1 - 0.19 11.4 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SKI PF01202.22 ORY05991.1 - 0.5 10.5 2.1 9.4 6.3 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase RRM_1 PF00076.22 ORY05992.1 - 3.3e-11 42.8 0.0 2.6e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.29 ORY05993.1 - 6.3e-32 111.1 0.0 1.1e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY05993.1 - 1.4e-18 67.5 11.9 1.6e-18 67.4 5.8 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORY05993.1 - 7.1e-07 29.8 0.2 0.00021 21.8 0.1 2.9 2 0 0 2 2 2 1 DUSP domain ubiquitin PF00240.23 ORY05993.1 - 9.8e-07 28.4 0.1 2.8e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY05993.1 - 0.054 13.3 0.3 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like MIF4G_like_2 PF09090.11 ORY05994.1 - 5.2e-63 213.0 2.4 9.6e-63 212.1 2.4 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 ORY05994.1 - 1.3e-54 184.9 0.2 3.4e-54 183.5 0.2 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 ORY05994.1 - 1.4e-12 47.7 0.8 3.9e-12 46.3 0.1 2.2 2 0 0 2 2 2 1 MIF4G domain Tai4 PF16695.5 ORY05994.1 - 0.08 13.5 0.1 0.23 12.0 0.1 1.8 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein ATP-synt_S1 PF05827.12 ORY05995.1 - 2e-08 34.2 0.0 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) V-ATPase_C PF03223.15 ORY05996.1 - 2.5e-137 458.2 7.4 2.8e-137 458.1 7.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Baculo_PEP_C PF04513.12 ORY05996.1 - 0.12 12.4 1.0 0.18 11.9 0.5 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Paf67 PF10255.9 ORY05997.1 - 1e-176 587.9 3.0 1e-176 587.9 3.0 1.3 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ORY05997.1 - 0.0054 16.8 0.0 0.056 13.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY05997.1 - 0.041 13.7 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY05997.1 - 0.059 13.7 0.1 0.39 11.1 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat DcpS_C PF11969.8 ORY05998.1 - 1.4e-16 61.0 0.0 2.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORY05998.1 - 1.7e-09 38.3 0.0 2.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 ORY05998.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FUSC_2 PF13515.6 ORY05999.1 - 5.3e-17 62.1 17.4 8.7e-17 61.4 17.4 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ALMT PF11744.8 ORY05999.1 - 3e-15 56.0 20.2 5e-15 55.3 19.5 1.6 1 1 1 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 ORY05999.1 - 1.4e-10 41.4 0.0 2.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ORY05999.1 - 1.4e-09 37.1 10.5 2.4e-09 36.3 10.5 1.3 1 1 0 1 1 1 1 Fusaric acid resistance protein family Zea_mays_MuDR PF05928.11 ORY06000.1 - 0.029 14.0 0.3 0.33 10.6 0.1 2.0 1 1 1 2 2 2 0 Zea mays MURB-like protein (MuDR) ABC_membrane PF00664.23 ORY06001.1 - 7.2e-45 153.8 10.5 1e-44 153.3 10.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY06001.1 - 2.2e-33 115.6 0.0 4.4e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY06001.1 - 1.4e-06 27.9 2.8 5e-05 22.9 0.1 2.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY06001.1 - 6.5e-05 23.2 0.1 0.00031 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY06001.1 - 0.0071 16.9 0.0 0.031 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 ORY06001.1 - 0.019 14.8 0.6 0.13 12.0 0.1 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.6 ORY06001.1 - 0.023 14.4 0.1 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane_2 PF06472.15 ORY06001.1 - 0.033 13.6 1.1 0.06 12.7 1.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_16 PF13191.6 ORY06001.1 - 0.044 14.2 0.1 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 ORY06001.1 - 0.049 12.4 0.1 0.085 11.6 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 ORY06001.1 - 0.094 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY06001.1 - 0.11 12.0 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF21 PF01595.20 ORY06001.1 - 0.51 10.0 6.6 0.17 11.6 2.4 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain AAA PF00004.29 ORY06001.1 - 0.88 10.0 2.5 21 5.6 2.5 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-H2C2_2 PF13465.6 ORY06002.1 - 3e-11 43.2 15.8 2.6e-07 30.7 4.6 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY06002.1 - 8.2e-09 35.5 12.4 6.8e-05 23.1 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY06002.1 - 3.1e-05 24.4 10.3 0.035 14.9 2.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-MIZ PF02891.20 ORY06002.1 - 0.008 15.9 3.5 0.87 9.4 1.2 2.2 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-C2H2_6 PF13912.6 ORY06002.1 - 0.0088 16.0 8.1 0.092 12.8 0.1 3.0 2 2 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY06002.1 - 0.014 15.7 0.6 0.029 14.6 0.6 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon DNase-RNase PF02577.14 ORY06002.1 - 0.015 15.0 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Bifunctional nuclease DUF2225 PF09986.9 ORY06002.1 - 0.028 14.2 0.5 0.031 14.0 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Mss4 PF04421.13 ORY06062.1 - 1.7e-23 82.6 0.0 2.2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein Tti2 PF10521.9 ORY06063.1 - 7.4e-40 137.2 0.6 1.2e-39 136.6 0.6 1.4 1 0 0 1 1 1 1 Tti2 family Terminase_GpA PF05876.12 ORY06063.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Pga1 PF10333.9 ORY06064.1 - 7.8e-06 25.9 1.2 1.4e-05 25.0 1.2 1.4 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator zf-CCCH_4 PF18044.1 ORY06065.1 - 6.5e-14 51.3 11.3 2.7e-08 33.4 2.0 2.1 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 ORY06065.1 - 8.6e-12 44.7 10.0 9e-06 25.5 2.2 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY06065.1 - 8.9e-10 38.3 21.5 8.3e-05 22.5 7.5 2.1 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 ORY06065.1 - 6.5e-06 26.8 10.1 0.0062 17.2 2.0 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 ORY06065.1 - 7.2e-05 23.0 5.4 8.1e-05 22.8 5.4 1.0 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORY06065.1 - 0.00011 22.5 16.9 0.00049 20.5 5.1 2.4 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Disintegrin PF00200.23 ORY06065.1 - 0.02 15.7 3.7 0.026 15.3 3.7 1.0 1 0 0 1 1 1 0 Disintegrin Opy2 PF09463.10 ORY06065.1 - 0.17 12.2 2.9 2 8.8 0.9 2.3 1 1 1 2 2 2 0 Opy2 protein Evr1_Alr PF04777.13 ORY06067.1 - 2e-33 114.8 0.8 2e-33 114.8 0.8 1.9 2 0 0 2 2 2 1 Erv1 / Alr family DUF1677 PF07911.13 ORY06067.1 - 0.0069 16.8 1.1 0.017 15.5 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1677) FOP_dimer PF09398.10 ORY06067.1 - 0.042 14.1 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 FOP N terminal dimerisation domain APOBEC4 PF18775.1 ORY06067.1 - 0.088 13.0 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 APOBEC4 DUF572 PF04502.13 ORY06068.1 - 1.4e-78 264.9 11.9 1.6e-78 264.7 11.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Lar_restr_allev PF14354.6 ORY06068.1 - 0.058 13.8 0.6 0.16 12.4 0.6 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar NACHT PF05729.12 ORY06068.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain HypA PF01155.19 ORY06068.1 - 0.2 11.7 1.1 0.38 10.8 0.2 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 ORY06068.1 - 0.26 11.4 2.0 17 5.6 0.3 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_4 PF13717.6 ORY06068.1 - 0.29 11.1 2.4 4.3 7.3 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF2175 PF09943.9 ORY06068.1 - 6.2 7.2 6.3 2.4 8.5 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) GIY-YIG PF01541.24 ORY06069.1 - 1.6e-09 37.9 0.0 3.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF1752 PF08550.10 ORY06070.1 - 6.7e-12 45.0 3.1 1.2e-11 44.2 3.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Snf7 PF03357.21 ORY06071.1 - 1.3e-29 103.0 22.7 2e-29 102.4 22.6 1.3 1 1 0 1 1 1 1 Snf7 FapA PF03961.13 ORY06071.1 - 0.085 11.5 7.5 0.1 11.2 7.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CEP19 PF14933.6 ORY06071.1 - 0.28 11.5 5.1 0.46 10.8 5.1 1.4 1 0 0 1 1 1 0 CEP19-like protein DUF445 PF04286.12 ORY06071.1 - 0.44 10.3 10.5 0.57 9.9 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PhoU PF01895.19 ORY06071.1 - 0.9 10.0 7.3 0.79 10.2 0.5 2.8 1 1 0 2 2 2 0 PhoU domain Bestrophin PF01062.21 ORY06071.1 - 1.1 8.6 4.1 1.5 8.1 4.1 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Nucleoside_tran PF01733.18 ORY06072.1 - 2.3e-57 194.7 14.1 2.3e-57 194.7 14.1 2.1 2 1 0 2 2 2 1 Nucleoside transporter PufQ PF05398.11 ORY06072.1 - 0.092 12.9 0.2 0.8 9.9 0.0 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF5080 PF16883.5 ORY06072.1 - 0.34 11.0 9.9 0.02 15.0 3.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5080) Exo_endo_phos PF03372.23 ORY06073.1 - 4.1e-05 23.2 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family dCMP_cyt_deam_1 PF00383.23 ORY06074.1 - 4e-05 23.4 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY06074.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase NtCtMGAM_N PF16863.5 ORY06074.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase F-box-like PF12937.7 ORY06075.1 - 3.4e-09 36.4 0.1 9.7e-09 35.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY06075.1 - 0.0024 18.2 12.8 0.0078 16.6 0.4 4.8 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY06075.1 - 0.0034 17.3 1.0 1.2 9.3 0.0 3.8 3 0 0 3 3 3 1 Leucine Rich repeat F-box_5 PF18511.1 ORY06075.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box DUF3630 PF12305.8 ORY06075.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) FA_hydroxylase PF04116.13 ORY06076.1 - 8.4e-23 81.2 12.0 8.4e-23 81.2 12.0 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily HPS6 PF15702.5 ORY06076.1 - 0.073 11.0 0.0 0.091 10.7 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein V-SNARE_C PF12352.8 ORY06077.1 - 2e-14 53.6 8.2 3.5e-14 52.8 3.3 2.7 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Wtap PF17098.5 ORY06077.1 - 0.013 15.4 3.0 0.03 14.2 2.9 1.8 1 1 0 1 1 1 0 WTAP/Mum2p family NifW PF03206.14 ORY06077.1 - 0.019 15.4 1.2 0.06 13.9 0.4 2.1 1 1 1 2 2 2 0 Nitrogen fixation protein NifW DUF1517 PF07466.11 ORY06077.1 - 0.036 14.2 1.7 0.046 13.9 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Gon7 PF08738.10 ORY06077.1 - 0.037 14.1 0.5 0.094 12.8 0.5 1.6 1 0 0 1 1 1 0 Gon7 family Sec20 PF03908.13 ORY06077.1 - 0.05 13.5 7.3 0.08 12.9 0.2 3.2 2 1 1 3 3 3 0 Sec20 DUF1664 PF07889.12 ORY06077.1 - 1.4 9.0 5.1 7.2 6.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 ORY06077.1 - 4.3 7.0 9.6 2.7 7.7 2.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF148 PF02520.17 ORY06077.1 - 5.1 7.3 10.3 0.29 11.2 3.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF148 YecM PF06185.12 ORY06078.1 - 6.1e-32 110.7 0.1 2.6e-30 105.4 0.1 2.0 1 1 0 1 1 1 1 YecM protein Ribosomal_S30AE PF02482.19 ORY06078.1 - 0.045 14.5 0.0 0.14 12.9 0.0 1.9 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein F-box PF00646.33 ORY06079.1 - 4.7e-07 29.5 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY06079.1 - 0.00023 21.0 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY06079.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 F-box ATG22 PF11700.8 ORY06080.1 - 1.7e-148 495.2 27.7 2e-148 495.0 27.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TssN PF17555.2 ORY06080.1 - 2.9e-07 30.2 4.4 2.9e-07 30.2 4.4 3.2 2 2 1 4 4 4 1 Type VI secretion system, TssN MFS_1 PF07690.16 ORY06080.1 - 6.6e-07 28.6 48.2 2.1e-05 23.6 27.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3742 PF12553.8 ORY06080.1 - 0.17 12.0 0.1 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) TMEM173 PF15009.6 ORY06080.1 - 1.6 7.8 3.6 1.3 8.2 0.4 2.2 2 0 0 2 2 2 0 Transmembrane protein 173 DASH_Ask1 PF08655.10 ORY06081.1 - 3.2e-19 68.6 0.7 6.2e-19 67.6 0.7 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 GrpE PF01025.19 ORY06081.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 GrpE 14-3-3 PF00244.20 ORY06082.1 - 2.2e-105 351.1 6.9 2.8e-105 350.8 6.9 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 ORY06082.1 - 0.023 14.7 0.3 0.057 13.4 0.3 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF GDPD PF03009.17 ORY06082.1 - 0.044 13.5 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Sec7 PF01369.20 ORY06083.1 - 6.1e-34 117.3 0.6 3.4e-33 114.9 0.3 2.0 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 ORY06083.1 - 4.1e-29 101.4 0.0 9.1e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY06083.1 - 2.8e-09 37.4 0.0 6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Homeodomain PF00046.29 ORY06084.1 - 2.2e-15 56.2 3.7 3.5e-15 55.6 3.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY06084.1 - 0.009 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 ORY06084.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain SURF1 PF02104.15 ORY06085.1 - 6.2e-45 153.6 0.0 7.8e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family VID27 PF08553.10 ORY06086.1 - 3.5e-167 555.9 0.6 1.2e-166 554.1 0.1 1.8 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 ORY06086.1 - 1.2e-49 168.5 0.5 1.2e-49 168.5 0.5 3.6 3 1 1 4 4 4 2 VID27 N-terminal region VID27_PH PF17747.1 ORY06086.1 - 4.9e-30 104.0 7.0 3.4e-29 101.3 1.4 2.7 2 1 0 2 2 2 1 VID27 PH-like domain Voldacs PF03517.13 ORY06086.1 - 0.0055 16.8 0.9 0.013 15.6 0.9 1.6 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Mcl1_mid PF12341.8 ORY06086.1 - 0.037 13.4 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region YL1 PF05764.13 ORY06086.1 - 0.38 10.8 7.5 0.68 10.0 7.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 ORY06086.1 - 0.41 11.1 6.8 1.1 9.7 6.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 ORY06086.1 - 0.72 9.4 4.8 1.3 8.5 4.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cyclin_N PF00134.23 ORY06087.1 - 2.2e-08 33.9 0.0 3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY06087.1 - 3.8e-07 30.6 0.0 4.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Trimer_CC PF08954.11 ORY06087.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Trimerisation motif CENP-W PF15510.6 ORY06087.1 - 0.098 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 CENP-W protein Chitin_synth_1 PF01644.17 ORY06088.1 - 1.2e-73 246.5 0.1 1.7e-73 245.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY06088.1 - 2.2e-26 91.6 0.0 4.1e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY06088.1 - 8.9e-26 90.6 3.2 3e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY06088.1 - 9.2e-10 38.8 0.2 9.2e-10 38.8 0.2 3.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY06088.1 - 0.0011 18.9 0.0 0.007 16.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 TniB PF05621.11 ORY06088.1 - 0.012 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ribosomal_L34 PF00468.17 ORY06089.1 - 5.6e-21 74.2 6.4 7.9e-21 73.8 6.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Cyclin_N PF00134.23 ORY06090.1 - 0.00013 21.8 0.4 0.0077 16.0 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin PF08613.11 ORY06090.1 - 0.00099 19.5 0.9 0.0056 17.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin bMG3 PF11974.8 ORY06090.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Ribosomal_S7 PF00177.21 ORY06091.1 - 1.3e-37 128.7 0.7 1.6e-37 128.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e UBA_4 PF14555.6 ORY06092.1 - 2.7e-06 27.1 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Binary_toxB PF03495.14 ORY06093.1 - 0.28 11.4 2.1 7 6.9 0.1 2.5 1 1 1 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DEAD PF00270.29 ORY06094.1 - 2.5e-51 173.9 0.0 5.4e-50 169.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY06094.1 - 1.9e-26 92.5 0.0 8.6e-26 90.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Synaptobrevin PF00957.21 ORY06094.1 - 0.52 10.1 2.4 1.4 8.8 2.4 1.7 1 0 0 1 1 1 0 Synaptobrevin Gly_rich PF12810.7 ORY06094.1 - 2.2 8.1 12.6 0.01 15.8 3.8 1.5 2 0 0 2 2 2 0 Glycine rich protein Vps51 PF08700.11 ORY06095.1 - 3.6e-10 39.8 0.1 3.7e-09 36.5 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 DUF1077 PF06417.12 ORY06096.1 - 1.7e-44 150.6 0.9 2.2e-44 150.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Prismane PF03063.20 ORY06097.1 - 1.4e-140 469.4 0.0 1.8e-140 469.0 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 ORY06097.1 - 6.4e-47 160.0 0.2 1.3e-46 158.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY06097.1 - 4.3e-29 101.5 0.0 1.1e-28 100.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY06097.1 - 2.1e-05 25.1 0.1 9.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain VIT1 PF01988.19 ORY06097.1 - 0.018 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 VIT family Flavodoxin_5 PF12724.7 ORY06097.1 - 0.027 14.7 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain NAD_binding_6 PF08030.12 ORY06097.1 - 0.18 11.9 0.1 1.2 9.3 0.0 2.2 2 1 0 3 3 3 0 Ferric reductase NAD binding domain HSF_DNA-bind PF00447.17 ORY06098.1 - 9.4e-27 93.5 0.6 1.7e-26 92.7 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Cep57_CLD_2 PF14197.6 ORY06098.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Arginosuc_synth PF00764.19 ORY06099.1 - 2e-154 514.6 0.0 2.3e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORY06099.1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORY06099.1 - 0.03 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase DUF3700 PF12481.8 ORY06100.1 - 0.034 13.6 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein p450 PF00067.22 ORY06101.1 - 1.2e-55 189.1 0.1 1.6e-55 188.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 LSM PF01423.22 ORY06102.1 - 5.6e-17 61.2 0.0 7e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY06102.1 - 0.0087 16.2 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain ATP_sub_h PF10775.9 ORY06103.1 - 3.2e-24 84.7 0.6 3.8e-24 84.5 0.6 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h Sigma70_r2 PF04542.14 ORY06103.1 - 0.19 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-70 region 2 TPR_1 PF00515.28 ORY06104.1 - 4.4e-38 127.6 28.6 1.3e-07 31.1 0.1 15.0 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 ORY06104.1 - 8.6e-35 116.1 40.7 2.1e-07 30.5 0.2 17.1 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_19 PF14559.6 ORY06104.1 - 2.1e-26 92.2 28.3 3.1e-05 24.4 0.6 11.2 6 3 5 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.6 ORY06104.1 - 2.9e-26 89.9 24.0 0.014 16.1 0.0 15.8 8 6 10 18 18 17 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY06104.1 - 3.1e-26 91.5 25.6 0.00012 22.3 1.4 10.4 7 3 3 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 ORY06104.1 - 1e-22 78.4 35.3 5.8e-05 23.0 0.1 15.8 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_6 PF13174.6 ORY06104.1 - 2.9e-20 71.5 28.3 0.044 14.4 0.0 14.5 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY06104.1 - 2.2e-14 52.3 12.0 0.035 14.1 0.0 10.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY06104.1 - 3.5e-14 52.1 14.7 0.82 10.2 0.0 13.4 14 1 0 14 14 13 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY06104.1 - 5e-14 52.7 31.1 1.8e-05 25.3 0.0 8.9 10 1 2 12 12 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY06104.1 - 8.6e-14 51.0 21.4 1.3e-05 24.8 0.0 9.9 10 1 2 12 12 11 3 TPR repeat TPR_9 PF13371.6 ORY06104.1 - 1.6e-09 37.8 9.0 0.0073 16.4 0.0 7.7 6 4 3 10 10 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY06104.1 - 1.3e-06 28.5 19.6 0.13 12.5 0.0 7.1 6 3 2 8 8 7 4 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 ORY06104.1 - 3.1e-06 26.8 14.6 0.0088 15.5 6.3 4.7 4 2 1 5 5 5 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 ORY06104.1 - 2.8e-05 23.5 12.8 0.00082 18.7 0.2 5.4 3 3 2 5 5 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 ORY06104.1 - 0.00055 18.8 1.0 1.6 7.4 0.0 4.2 4 0 0 4 4 4 1 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 ORY06104.1 - 0.00095 19.0 25.2 0.47 10.4 0.1 10.7 14 0 0 14 14 12 2 Tetratricopeptide repeat DUF2989 PF11207.8 ORY06104.1 - 0.0042 16.9 0.4 0.0042 16.9 0.4 4.9 6 0 0 6 6 5 1 Protein of unknown function (DUF2989) HrpB1_HrpK PF09613.10 ORY06104.1 - 0.012 15.3 0.1 1.8 8.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2225 PF09986.9 ORY06104.1 - 0.018 14.8 6.1 1.8 8.3 0.5 4.5 3 3 2 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 ORY06104.1 - 0.046 14.4 6.3 6.8 7.6 0.5 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 ORY06104.1 - 0.087 12.4 0.1 0.087 12.4 0.1 3.2 3 0 0 3 3 2 0 Foie gras liver health family 1 Ribosomal_L2_C PF03947.18 ORY06105.1 - 3.7e-49 166.1 3.1 5.8e-49 165.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY06105.1 - 5.1e-16 58.4 0.0 1.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PI3_PI4_kinase PF00454.27 ORY06106.1 - 7.4e-42 143.9 0.0 1e-39 136.9 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY06106.1 - 8.6e-21 74.2 0.3 2.1e-20 72.9 0.3 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) tRNA-synt_1d PF00750.19 ORY06109.1 - 4.6e-107 358.0 9.5 5.7e-107 357.7 9.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY06109.1 - 2.9e-24 85.5 0.1 7.4e-24 84.2 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORY06109.1 - 6.3e-10 39.5 0.2 2e-09 37.9 0.2 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF5370 PF17340.2 ORY06109.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5370) Glyco_trans_4_2 PF13477.6 ORY06109.1 - 0.12 12.4 0.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like NUDIX PF00293.28 ORY06110.1 - 3.5e-13 49.7 0.2 6.2e-13 48.9 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain FYVE PF01363.21 ORY06111.1 - 5.1e-10 39.3 10.1 9.4e-10 38.5 10.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 ORY06111.1 - 0.0017 18.8 0.1 0.005 17.3 0.1 1.9 1 1 0 1 1 1 1 PH domain FYVE_2 PF02318.16 ORY06111.1 - 0.0064 16.7 7.3 0.0064 16.7 7.3 1.8 3 0 0 3 3 3 1 FYVE-type zinc finger PH_4 PF15404.6 ORY06111.1 - 0.073 12.9 0.0 0.28 11.0 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Baculo_ME53 PF06061.11 ORY06111.1 - 0.72 9.0 6.1 0.32 10.2 0.4 2.1 1 1 1 2 2 2 0 Baculoviridae ME53 zf-B_box PF00643.24 ORY06111.1 - 8.3 6.7 9.8 9.9 6.4 5.8 2.4 2 0 0 2 2 2 0 B-box zinc finger AMP-binding PF00501.28 ORY06112.1 - 3.7e-84 282.8 0.0 4.8e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY06112.1 - 4.4e-10 40.4 0.0 1e-09 39.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 ORY06113.1 - 9.4e-70 235.0 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06113.1 - 1e-32 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY06113.1 - 0.0023 16.9 0.2 0.0041 16.1 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY06113.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY06113.1 - 0.0077 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY06113.1 - 0.011 15.4 0.1 0.082 12.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family YukC PF10140.9 ORY06113.1 - 0.016 14.1 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase_fungal PF17667.1 ORY06113.1 - 0.079 11.7 0.0 0.18 10.5 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase TFIID_20kDa PF03847.13 ORY06115.1 - 5.3e-34 116.5 0.7 6.9e-34 116.2 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 ORY06115.1 - 9.3e-07 29.0 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY06115.1 - 3.6e-06 27.4 0.1 6.2e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORY06115.1 - 0.0025 17.9 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 ORY06115.1 - 0.094 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RNA_pol_A_bac PF01000.26 ORY06116.1 - 1.4e-36 125.2 0.0 2.5e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORY06116.1 - 7.3e-21 73.4 0.0 9.4e-21 73.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1325 PF07039.11 ORY06117.1 - 2.3e-28 98.9 0.1 4.4e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 ORY06117.1 - 0.018 15.5 0.1 0.075 13.5 0.1 2.1 2 0 0 2 2 2 0 Agenet domain BTB PF00651.31 ORY06118.1 - 0.013 15.7 0.1 0.91 9.8 0.0 2.4 1 1 1 2 2 2 0 BTB/POZ domain UBD PF16455.5 ORY06173.1 - 1.1e-28 99.5 0.0 1.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 ORY06173.1 - 6.5e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY06173.1 - 6.4e-06 25.9 0.1 1.2e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORY06173.1 - 0.0015 18.7 0.1 0.0032 17.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY06173.1 - 0.0048 17.4 0.1 0.011 16.3 0.1 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ARPC4 PF05856.12 ORY06174.1 - 3.6e-82 273.9 7.8 4e-82 273.8 7.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 ORY06174.1 - 0.045 13.9 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 Sm_like domain Acetyltransf_1 PF00583.25 ORY06175.1 - 3e-18 66.1 0.1 3.7e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY06175.1 - 5.6e-10 39.5 0.0 8.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY06175.1 - 2.2e-09 37.3 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY06175.1 - 7.6e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ORY06175.1 - 0.0009 19.4 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NMT_C PF02799.15 ORY06175.1 - 0.0015 18.1 0.2 0.003 17.1 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_13 PF13880.6 ORY06175.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 ORY06175.1 - 0.095 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 ORY06175.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Ras PF00071.22 ORY06176.1 - 1.3e-60 203.6 0.3 1.6e-60 203.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY06176.1 - 2.3e-20 73.0 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY06176.1 - 7e-10 38.6 0.0 8.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY06176.1 - 5.2e-05 23.2 0.0 0.061 13.2 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORY06176.1 - 0.00011 21.8 0.1 0.00024 20.7 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ORY06176.1 - 0.00081 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORY06176.1 - 0.0009 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY06176.1 - 0.0068 16.0 0.1 0.021 14.3 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Ser_hydrolase PF06821.13 ORY06176.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase AvrLm4-7 PF18661.1 ORY06176.1 - 0.098 13.7 0.4 0.29 12.2 0.3 1.8 1 1 1 2 2 2 0 Avirulence Effector AvrLm4-7 CbiA PF01656.23 ORY06176.1 - 0.13 12.4 1.0 1.4 9.0 1.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ORY06176.1 - 0.18 11.6 2.3 1 9.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PCI PF01399.27 ORY06177.1 - 2.2e-14 53.8 0.0 5e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain COX5A PF02284.16 ORY06179.1 - 5.7e-30 103.4 0.5 7e-29 99.9 0.5 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Va Pkinase PF00069.25 ORY06181.1 - 2.2e-63 214.1 0.0 2.6e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06181.1 - 4e-42 144.3 0.0 5.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY06181.1 - 2.6e-07 30.3 0.0 3.9e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY06181.1 - 0.00033 19.7 0.1 0.00064 18.8 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY06181.1 - 0.0011 17.8 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY06181.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family NIF PF03031.18 ORY06182.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PAS_4 PF08448.10 ORY06182.1 - 0.011 16.0 0.2 0.032 14.5 0.1 1.8 2 0 0 2 2 2 0 PAS fold RmlD_sub_bind PF04321.17 ORY06182.1 - 0.049 12.7 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF5525 PF17663.1 ORY06182.1 - 0.19 9.7 8.2 0.25 9.4 8.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DEC-1_N PF04625.13 ORY06182.1 - 7.5 5.4 8.9 11 4.9 8.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peroxin-3 PF04882.12 ORY06183.1 - 3.4e-91 306.6 0.1 5.3e-62 210.3 0.0 2.0 2 0 0 2 2 2 2 Peroxin-3 Ndc80_HEC PF03801.13 ORY06184.1 - 3.8e-50 169.5 0.2 1e-49 168.0 0.2 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 ORY06184.1 - 9.9e-11 41.6 3.3 9.9e-11 41.6 3.3 5.7 5 2 2 7 7 7 1 Domain of unknown function (DUF5595) DHR10 PF18595.1 ORY06184.1 - 0.0058 16.7 16.2 0.0058 16.7 16.2 4.1 3 2 1 4 4 4 2 Designed helical repeat protein 10 domain NLRC4_HD PF17889.1 ORY06184.1 - 0.41 11.0 0.1 0.41 11.0 0.1 3.6 4 2 0 4 4 4 0 NLRC4 helical domain Golgin_A5 PF09787.9 ORY06184.1 - 0.56 9.6 47.0 0.011 15.3 16.1 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 ABC_tran_CTD PF16326.5 ORY06184.1 - 1.3 9.3 39.7 0.35 11.1 8.0 5.1 2 2 2 4 4 4 0 ABC transporter C-terminal domain DUF4407 PF14362.6 ORY06184.1 - 2 7.7 32.7 0.99 8.7 6.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) ERM PF00769.19 ORY06184.1 - 4 7.2 52.4 3.1 7.6 26.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family MRFAP1 PF15155.6 ORY06184.1 - 4.3 7.9 13.2 1.3 9.6 1.7 3.4 2 1 1 3 3 3 0 MORF4 family-associated protein1 Spc7 PF08317.11 ORY06184.1 - 5 5.9 61.4 0.46 9.3 22.5 4.1 2 2 2 4 4 4 0 Spc7 kinetochore protein DUF883 PF05957.13 ORY06184.1 - 7.6 7.2 20.1 1.8 9.2 0.3 5.0 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Mon1 PF03164.14 ORY06185.1 - 1.1e-145 485.8 1.2 1.3e-145 485.5 1.2 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF3922 PF13059.6 ORY06185.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) GFD1 PF17331.2 ORY06185.1 - 0.18 12.1 1.9 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 GFD1 mRNA transport factor DUF3234 PF11572.8 ORY06186.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) Bax1-I PF01027.20 ORY06187.1 - 2e-50 171.5 31.5 2.3e-50 171.3 31.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_P21 PF05313.12 ORY06187.1 - 0.078 12.5 5.9 0.14 11.7 5.9 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Trypsin PF00089.26 ORY06188.1 - 9.5e-39 133.5 0.0 1.2e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 ORY06188.1 - 2.5e-06 28.4 0.1 4.4e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Fz PF01392.22 ORY06189.1 - 0.00047 20.7 2.4 0.00076 20.1 2.4 1.4 1 0 0 1 1 1 1 Fz domain Glyco_transf_10 PF00852.19 ORY06190.1 - 4.2e-43 147.1 0.4 5.9e-43 146.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 ORY06190.1 - 1.1e-13 51.6 2.7 5.5e-13 49.3 0.1 2.7 4 0 0 4 4 4 1 Fucosyltransferase, N-terminal Semialdhyde_dh PF01118.24 ORY06190.1 - 0.041 14.3 0.0 0.1 13.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_trans_1_2 PF13524.6 ORY06190.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_hydro_31 PF01055.26 ORY06191.1 - 1.8e-156 521.8 1.5 2.3e-156 521.4 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ORY06191.1 - 5e-32 110.5 0.0 2.5e-31 108.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ORY06191.1 - 1.8e-09 37.8 0.0 6.2e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Peptidase_S15 PF02129.18 ORY06192.1 - 1.6e-06 28.0 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 ORY06192.1 - 9.2e-06 25.5 0.0 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY06192.1 - 1.8e-05 24.5 1.4 0.44 10.1 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY06192.1 - 2.4e-05 23.7 0.0 0.024 13.9 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY06192.1 - 5.7e-05 23.8 0.0 0.0082 16.8 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY06192.1 - 0.00037 20.0 0.0 0.0028 17.2 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORY06192.1 - 0.07 12.7 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Polysacc_deac_1 PF01522.21 ORY06193.1 - 2.2e-29 101.9 0.0 3.7e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 ORY06194.1 - 7.6e-30 103.4 0.0 1.3e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Ribosomal_L7Ae PF01248.26 ORY06195.1 - 3.3e-24 84.4 0.0 3.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pectate_lyase_3 PF12708.7 ORY06196.1 - 6.7e-05 22.8 0.5 0.00037 20.4 0.0 2.1 2 0 0 2 2 2 1 Pectate lyase superfamily protein RNA_binding PF01877.17 ORY06196.1 - 0.11 12.8 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 RNA binding Pkr1 PF08636.10 ORY06197.1 - 2.3e-20 72.5 1.6 2.7e-20 72.3 1.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF443 PF04276.12 ORY06197.1 - 0.013 15.3 0.7 0.015 15.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF1772 PF08592.11 ORY06197.1 - 0.035 14.4 0.1 0.041 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SLATT_4 PF18186.1 ORY06197.1 - 0.051 13.2 0.7 0.055 13.1 0.7 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Qua1 PF16274.5 ORY06197.1 - 0.063 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Qua1 domain DUF4692 PF15763.5 ORY06197.1 - 0.16 12.4 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Myco_arth_vir_N PF09610.10 ORY06197.1 - 0.82 9.8 4.3 0.79 9.9 1.2 2.3 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Galactosyl_T PF01762.21 ORY06198.1 - 3.2e-06 27.1 0.0 9.2e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 ORY06198.1 - 1.4e-05 24.7 0.1 0.00086 18.8 0.2 2.3 1 1 1 2 2 2 2 Fringe-like Fringe PF02434.16 ORY06199.1 - 3e-06 26.9 0.2 0.00039 19.9 0.2 2.2 1 1 1 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 ORY06199.1 - 6.6e-06 26.1 0.0 1.7e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 ORY06200.1 - 2.3e-06 27.3 0.1 0.00012 21.6 0.1 2.2 1 1 1 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 ORY06200.1 - 8e-06 25.8 0.0 0.0001 22.2 0.1 2.1 2 0 0 2 2 2 1 Galactosyltransferase Cyclin PF08613.11 ORY06204.1 - 8.5e-05 23.0 0.1 0.08 13.3 0.1 2.6 2 1 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 ORY06204.1 - 0.0087 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 ORY06205.1 - 1.1e-51 175.8 4.1 3e-42 144.8 3.6 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06205.1 - 2e-28 99.4 3.9 4.8e-26 91.6 3.0 3.0 2 1 0 3 3 3 2 Protein tyrosine kinase KA1 PF02149.19 ORY06205.1 - 1.4e-16 60.0 0.0 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 ORY06205.1 - 7e-06 25.2 1.4 7e-06 25.2 1.4 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 ORY06205.1 - 4.3e-05 23.0 0.7 8.6e-05 22.0 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY06205.1 - 0.00017 21.3 1.4 0.00055 19.6 1.1 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 ORY06205.1 - 0.00065 19.7 0.1 0.061 13.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 ORY06205.1 - 0.03 13.9 0.5 0.074 12.6 0.5 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Lectin_C PF00059.21 ORY06207.1 - 0.21 12.3 1.2 34 5.2 0.0 2.5 1 1 1 2 2 2 0 Lectin C-type domain DnaJ PF00226.31 ORY06208.1 - 9.5e-15 54.5 3.4 2.6e-14 53.1 0.9 2.5 2 1 0 2 2 2 1 DnaJ domain Pex2_Pex12 PF04757.14 ORY06208.1 - 0.031 13.9 3.2 0.033 13.8 0.3 2.3 1 1 2 3 3 3 0 Pex2 / Pex12 amino terminal region Com_YlbF PF06133.11 ORY06209.1 - 0.1 13.2 0.7 0.33 11.6 0.7 1.9 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF4611 PF15387.6 ORY06209.1 - 0.14 12.4 0.4 0.23 11.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RdRP PF05183.12 ORY06210.1 - 1.2e-162 542.6 0.0 1.6e-162 542.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase PET PF06297.14 ORY06210.1 - 0.072 13.4 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 PET Domain Chlam_vir PF05475.11 ORY06210.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Pgp3 C-terminal domain Sugar_tr PF00083.24 ORY06268.1 - 1.9e-85 287.5 7.9 2.4e-85 287.1 7.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY06268.1 - 2.1e-25 89.4 11.5 2.1e-25 89.4 11.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 ORY06269.1 - 1.1e-46 159.4 0.0 2.9e-35 121.7 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY06269.1 - 5.5e-18 65.2 0.2 4.7e-11 42.5 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY06269.1 - 8.2e-11 41.7 0.0 5.5e-09 35.7 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY06269.1 - 1.3e-10 41.0 0.2 1.4e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORY06269.1 - 4.4e-08 32.6 0.0 1.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 ORY06269.1 - 6.3e-08 32.7 0.0 1e-06 28.9 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY06269.1 - 8.5e-08 32.3 0.5 3.5e-06 27.1 0.2 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ORY06269.1 - 1.6e-06 28.0 0.0 0.00019 21.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY06269.1 - 3.3e-05 23.4 0.0 0.00013 21.4 0.0 2.1 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORY06269.1 - 9.2e-05 21.3 0.1 0.00019 20.3 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 ORY06269.1 - 0.00097 19.2 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORY06269.1 - 0.0029 16.9 0.0 0.0074 15.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ORY06269.1 - 0.003 16.7 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY06269.1 - 0.0057 17.2 0.0 0.033 14.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY06269.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY06269.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 ORY06269.1 - 0.21 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glu_dehyd_C PF16912.5 ORY06269.1 - 0.21 11.0 0.0 0.47 9.9 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus IP_trans PF02121.18 ORY06270.1 - 0.031 13.8 0.1 0.035 13.7 0.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein LON_substr_bdg PF02190.16 ORY06271.1 - 1.3e-18 67.6 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 ORY06271.1 - 3.4e-12 46.0 31.9 7.6e-11 41.7 10.6 3.7 3 1 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY06271.1 - 3e-10 39.8 27.7 1.6e-07 31.0 6.6 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY06271.1 - 8.5e-10 38.5 34.1 3.8e-08 33.2 7.3 4.3 3 2 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 ORY06271.1 - 2.9e-09 36.7 33.2 1e-06 28.6 10.6 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY06271.1 - 1.8e-08 34.4 27.9 5.7e-05 23.2 9.8 3.2 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 ORY06271.1 - 1.3e-07 31.9 11.1 1.3e-07 31.9 11.1 4.0 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 ORY06271.1 - 4.3e-07 29.7 35.6 3.8e-06 26.7 10.9 3.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY06271.1 - 6e-06 26.0 30.7 3.2e-05 23.7 8.1 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY06271.1 - 1.2e-05 25.3 17.9 2.4e-05 24.4 4.7 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_4 PF14570.6 ORY06271.1 - 0.0038 17.0 3.1 0.0038 17.0 3.1 4.1 3 2 1 4 4 4 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ORY06271.1 - 0.0083 16.4 5.5 0.0083 16.4 5.5 3.2 3 0 0 3 3 2 1 RING-H2 zinc finger domain U-box PF04564.15 ORY06271.1 - 0.046 13.9 0.3 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 U-box domain DHODB_Fe-S_bind PF10418.9 ORY06271.1 - 7.7 6.4 8.4 8.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B LON_substr_bdg PF02190.16 ORY06272.1 - 2.3e-31 109.3 0.0 3.1e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 ORY06272.1 - 3.5e-10 39.6 13.1 3.5e-10 39.6 13.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY06272.1 - 3.4e-09 36.4 21.1 2.9e-08 33.4 8.9 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY06272.1 - 7e-09 35.7 26.2 7.8e-06 26.0 12.3 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY06272.1 - 1.4e-08 34.6 7.7 1.4e-08 34.6 7.7 3.4 4 1 0 4 4 4 2 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY06272.1 - 8.4e-08 32.0 26.9 1.8e-06 27.7 13.5 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY06272.1 - 8.6e-08 32.4 13.0 8.6e-08 32.4 13.0 3.1 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 ORY06272.1 - 6.6e-07 29.2 26.7 2.7e-05 24.0 14.1 2.7 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY06272.1 - 2.6e-05 24.0 10.1 2.6e-05 24.0 10.1 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY06272.1 - 0.0025 17.9 7.7 0.0025 17.9 7.7 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 ORY06272.1 - 0.014 15.6 0.4 0.095 12.9 0.0 2.5 3 0 0 3 3 3 0 U-box domain zf-RING_4 PF14570.6 ORY06272.1 - 0.46 10.3 16.2 0.52 10.2 8.2 3.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ORY06272.1 - 7.2 7.0 20.1 0.12 12.7 11.2 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain TerY_C PF15616.6 ORY06272.1 - 7.7 6.6 8.3 0.32 11.1 0.9 2.1 2 0 0 2 2 2 0 TerY-C metal binding domain SNARE_assoc PF09335.11 ORY06273.1 - 2.5e-10 40.9 3.4 4e-10 40.2 3.2 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein SNF5 PF04855.12 ORY06275.1 - 3.4e-54 184.1 2.7 3.4e-28 99.1 0.1 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 GATA PF00320.27 ORY06275.1 - 8.2e-12 44.5 3.2 1.6e-11 43.6 3.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Lactamase_B PF00753.27 ORY06276.1 - 3.1e-24 86.1 0.9 6.9e-24 84.9 0.9 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 ORY06276.1 - 3.4e-10 39.7 0.0 6.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 ORY06276.1 - 2.9e-08 33.5 0.1 4.1e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY06276.1 - 0.0025 17.8 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RRM_1 PF00076.22 ORY06277.1 - 1.1e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY06277.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Voltage_CLC PF00654.20 ORY06278.1 - 6.7e-92 308.5 29.1 6.7e-92 308.5 29.1 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY06278.1 - 3.1e-11 43.5 0.0 6e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain LacI PF00356.21 ORY06278.1 - 0.049 13.4 1.6 1.8 8.4 0.5 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Gar1 PF04410.14 ORY06279.1 - 3e-38 131.0 0.0 3.8e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.22 ORY06280.1 - 7.1e-06 25.8 0.1 0.00061 19.6 0.1 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY06280.1 - 0.0064 16.3 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif DNA_pol_A_exoN PF18305.1 ORY06280.1 - 0.19 12.1 0.6 0.41 11.0 0.3 1.7 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain Ribosomal_L7Ae PF01248.26 ORY06281.1 - 3e-20 71.7 1.2 6.2e-20 70.7 1.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L6e PF01159.19 ORY06282.1 - 2.4e-41 140.8 1.7 2.4e-41 140.8 1.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORY06282.1 - 2.9e-07 30.6 0.3 2.9e-07 30.6 0.3 2.4 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain WD40 PF00400.32 ORY06283.1 - 6e-15 55.4 9.9 1.7e-07 31.8 0.1 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 ORY06283.1 - 0.0029 17.5 0.0 0.83 9.5 0.1 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORY06283.1 - 0.0053 17.0 0.1 1.8 8.9 0.0 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Marek_SORF3 PF07153.11 ORY06283.1 - 0.0086 15.4 0.0 0.029 13.7 0.0 1.7 1 1 1 2 2 2 1 Marek's disease-like virus SORF3 protein Ribosomal_L37ae PF01780.19 ORY06284.1 - 6.4e-42 141.5 11.2 7.2e-42 141.4 11.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORY06284.1 - 0.0047 17.0 1.6 0.0067 16.5 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORY06284.1 - 0.014 15.4 1.8 0.022 14.7 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ORY06284.1 - 0.047 13.7 3.5 2.2 8.4 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 ORY06284.1 - 1.3 9.5 4.3 3.2 8.3 1.2 2.2 1 1 1 2 2 2 0 Zinc-finger double domain tRNA-synt_2b PF00587.25 ORY06285.1 - 3.5e-41 141.1 0.0 5.8e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY06285.1 - 3.2e-14 52.9 0.0 6.8e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 ORY06285.1 - 3.5e-14 52.6 0.0 6.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 ORY06285.1 - 2.4e-11 43.5 0.0 2.6e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_His PF13393.6 ORY06285.1 - 0.23 10.7 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Histidyl-tRNA synthetase IKI3 PF04762.12 ORY06286.1 - 1.6e-109 367.3 6.4 1.6e-109 367.3 6.4 1.5 2 0 0 2 2 2 1 IKI3 family DUF764 PF05561.11 ORY06286.1 - 0.001 18.9 1.3 0.002 17.9 0.5 1.8 2 0 0 2 2 2 1 Borrelia burgdorferi protein of unknown function (DUF764) TPR_1 PF00515.28 ORY06286.1 - 0.0016 18.2 2.2 0.0016 18.2 2.2 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Bystin PF05291.11 ORY06286.1 - 0.0024 17.2 0.0 0.0066 15.8 0.0 1.7 1 0 0 1 1 1 1 Bystin TPR_11 PF13414.6 ORY06286.1 - 0.0042 16.7 0.3 0.019 14.6 0.1 2.3 2 0 0 2 2 2 1 TPR repeat Se-cys_synth_N PF12390.8 ORY06286.1 - 0.0047 17.1 0.8 0.014 15.6 0.1 2.2 3 0 0 3 3 3 1 Selenocysteine synthase N terminal Tma16 PF11176.8 ORY06286.1 - 0.0071 16.2 0.2 0.0071 16.2 0.2 2.8 2 1 1 3 3 3 1 Translation machinery-associated protein 16 TPR_2 PF07719.17 ORY06286.1 - 0.0082 16.2 1.8 0.0082 16.2 1.8 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat NPV_P10 PF05531.12 ORY06286.1 - 0.023 15.2 5.2 0.47 10.9 0.4 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_14 PF13428.6 ORY06286.1 - 0.095 13.6 2.4 4.4 8.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 ORY06286.1 - 0.76 10.2 7.0 52 4.4 0.2 4.3 4 0 0 4 4 4 0 PPR repeat DNA_methylase PF00145.17 ORY06287.1 - 1.1e-38 133.5 0.0 1.4e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Ribosomal_S7 PF00177.21 ORY06288.1 - 4.1e-38 130.3 0.8 4.9e-38 130.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SURF4 PF02077.15 ORY06289.1 - 5.2e-93 311.5 10.3 6e-93 311.3 10.3 1.0 1 0 0 1 1 1 1 SURF4 family ATP-grasp_2 PF08442.10 ORY06290.1 - 3e-78 262.0 0.4 5.4e-78 261.2 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ORY06290.1 - 3.7e-27 95.0 0.4 6.3e-27 94.3 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ORY06290.1 - 1e-07 31.6 0.2 2e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ORY06290.1 - 0.00069 19.4 0.4 0.0049 16.7 0.1 2.4 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 ORY06290.1 - 0.0031 17.8 0.0 0.021 15.1 0.0 2.2 1 1 1 2 2 2 1 Orn/Lys/Arg decarboxylase, N-terminal domain Hist_deacetyl PF00850.19 ORY06291.1 - 1e-74 251.8 0.8 3.2e-74 250.2 0.2 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.9 ORY06291.1 - 1.3e-21 76.9 0.3 2.4e-21 76.0 0.3 1.3 1 0 0 1 1 1 1 Arb2 domain ATG13 PF10033.9 ORY06292.1 - 1.6e-64 217.9 0.5 2.9e-64 217.1 0.5 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Phage_spike_2 PF18781.1 ORY06292.1 - 0.005 16.8 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Phage spike trimer Pkinase PF00069.25 ORY06293.1 - 8.1e-47 159.8 0.0 5.7e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06293.1 - 4.5e-30 104.8 0.0 6.8e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY06293.1 - 9.6e-08 31.2 0.2 1.7e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY06293.1 - 0.001 19.1 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY06293.1 - 0.0044 16.4 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like GalP_UDP_transf PF01087.22 ORY06293.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Kdo PF06293.14 ORY06293.1 - 0.036 13.4 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BRO1 PF03097.18 ORY06294.1 - 3.1e-32 111.9 0.1 4e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 ORY06294.1 - 5.4e-09 35.5 2.9 3.6e-08 32.8 0.3 2.6 3 1 1 4 4 4 2 Family of unknown function (DUF5355) BCS1_N PF08740.11 ORY06295.1 - 1.1e-38 133.1 0.1 1.5e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORY06295.1 - 1.5e-21 77.2 0.0 3e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY06295.1 - 2.1e-05 23.8 0.0 3.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 ORY06295.1 - 0.0013 19.1 0.0 0.006 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY06295.1 - 0.0023 18.5 0.3 0.008 16.7 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 ORY06295.1 - 0.0061 16.8 0.0 0.05 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY06295.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY06295.1 - 0.023 14.8 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY06295.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 ORY06295.1 - 0.048 13.7 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 ORY06295.1 - 0.076 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 ORY06295.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ORY06295.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY06295.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 ORY06295.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 ORY06295.1 - 0.15 11.5 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY06295.1 - 0.17 12.1 0.0 0.66 10.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 ORY06295.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Glyco_hydro_31 PF01055.26 ORY06296.1 - 5.6e-149 497.1 1.3 7.8e-149 496.6 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY06296.1 - 4e-28 97.5 0.7 1.7e-26 92.3 0.3 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ORY06296.1 - 1.7e-07 31.4 0.1 5.5e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) zf-CCHC PF00098.23 ORY06297.1 - 1.4e-20 72.3 34.9 5.1e-06 26.3 1.1 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 ORY06297.1 - 0.0066 16.3 3.8 0.0066 16.3 3.8 3.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 ORY06297.1 - 0.025 14.3 30.3 0.41 10.4 1.1 4.4 3 1 1 4 4 4 0 Zinc knuckle Ribosomal_S5_C PF03719.15 ORY06298.1 - 3.2e-28 97.0 0.0 5.3e-27 93.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ORY06298.1 - 1.2e-17 63.6 1.0 2.3e-17 62.7 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain HisKA PF00512.25 ORY06298.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain ATP_bind_1 PF03029.17 ORY06299.1 - 2e-90 302.8 0.0 2.2e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ORY06299.1 - 1.1e-05 25.4 0.0 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 ORY06299.1 - 0.0034 17.9 0.0 0.0091 16.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY06299.1 - 0.0038 17.0 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORY06299.1 - 0.0063 16.4 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 ORY06299.1 - 0.008 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY06299.1 - 0.0088 16.4 0.0 0.19 12.2 0.0 2.4 2 1 0 2 2 2 1 RNA helicase Gtr1_RagA PF04670.12 ORY06299.1 - 0.011 15.1 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY06299.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain GTP_EFTU PF00009.27 ORY06299.1 - 0.018 14.6 0.1 3.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 ORY06299.1 - 0.029 13.4 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PPV_E1_C PF00519.17 ORY06299.1 - 0.039 12.8 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.6 ORY06299.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 ORY06299.1 - 0.044 13.9 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 ORY06299.1 - 0.047 14.2 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 ORY06299.1 - 0.051 13.9 0.3 0.1 13.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 ORY06299.1 - 0.063 13.3 0.0 0.083 13.0 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 ORY06299.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.29 ORY06299.1 - 0.073 13.5 0.0 0.29 11.5 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 ORY06299.1 - 0.077 12.9 0.7 14 5.6 0.1 2.6 2 2 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 ORY06299.1 - 0.082 12.8 0.2 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 ORY06299.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 ORY06299.1 - 0.087 11.6 0.2 0.66 8.7 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein T2SSE PF00437.20 ORY06299.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.7 ORY06299.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.6 ORY06299.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY06299.1 - 0.15 11.6 0.1 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 ORY06299.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 ORY06299.1 - 0.17 11.0 0.3 0.43 9.7 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 ORY06299.1 - 0.2 11.2 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 ORY06299.1 - 0.21 11.3 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF1180 PF06679.12 ORY06300.1 - 7.1 7.0 6.4 13 6.1 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) VSG_B PF13206.6 ORY06301.1 - 0.16 11.2 3.7 0.15 11.2 3.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain HSP20 PF00011.21 ORY06302.1 - 3.6e-22 78.4 0.1 4.3e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY06302.1 - 7.2e-15 54.3 0.0 3.5e-14 52.1 0.0 1.9 1 1 1 2 2 2 2 HSP20-like domain found in ArsA CS PF04969.16 ORY06302.1 - 0.05 14.6 0.1 0.11 13.5 0.0 1.6 1 1 0 1 1 1 0 CS domain GvpH PF05455.11 ORY06302.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 GvpH Phage_GPL PF05926.11 ORY06302.1 - 0.14 12.1 0.0 0.68 9.9 0.0 1.8 2 0 0 2 2 2 0 Phage head completion protein (GPL) Pkinase PF00069.25 ORY06303.1 - 4.6e-71 239.3 0.0 5.4e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06303.1 - 1.2e-31 110.0 0.0 1.6e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY06303.1 - 0.00059 19.2 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY06303.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY06303.1 - 0.013 15.4 0.1 0.15 12.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY06303.1 - 0.09 12.1 0.0 2.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Kinase-like MDM10 PF12519.8 ORY06304.1 - 6.3e-83 279.2 4.3 8.9e-80 268.8 2.8 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 ORY06304.1 - 2e-05 24.2 0.0 0.00023 20.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic porin Glyco_hydro_8 PF01270.17 ORY06305.1 - 6.9e-25 87.6 0.1 8.5e-25 87.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 F-box-like PF12937.7 ORY06307.1 - 9.9e-07 28.6 0.1 9.9e-07 28.6 0.1 3.2 3 1 0 3 3 3 1 F-box-like LRR_6 PF13516.6 ORY06307.1 - 0.67 10.2 8.3 32 4.9 0.2 6.1 7 0 0 7 7 7 0 Leucine Rich repeat His_Phos_2 PF00328.22 ORY06309.1 - 3.6e-19 69.4 0.0 3.3e-14 53.0 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Shadoo PF14999.6 ORY06309.1 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF3712 PF12505.8 ORY06310.1 - 7e-19 68.3 7.1 6e-12 45.9 0.0 4.6 5 0 0 5 5 5 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY06310.1 - 1.2e-07 32.2 0.2 0.03 14.9 0.0 4.7 4 1 0 4 4 4 2 Late embryogenesis abundant protein Invas_SpaK PF03519.14 ORY06310.1 - 0.089 12.9 0.0 23 5.1 0.0 2.9 3 0 0 3 3 3 0 Invasion protein B family Citrate_synt PF00285.21 ORY06311.1 - 8.5e-106 354.0 0.0 1e-105 353.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Aminotran_1_2 PF00155.21 ORY06312.1 - 2e-58 198.3 0.0 2.7e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 ORY06312.1 - 9.5e-35 118.3 0.0 7.7e-17 60.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY06312.1 - 4.9e-19 68.3 1.7 3.2e-06 27.2 0.1 3.5 3 0 0 3 3 3 3 Poly-adenylate binding protein, unique domain Aminotran_5 PF00266.19 ORY06312.1 - 3.6e-05 22.9 0.0 6.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Nup35_RRM PF05172.13 ORY06312.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif OKR_DC_1 PF01276.20 ORY06312.1 - 0.0032 16.3 0.0 0.0061 15.3 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 ORY06312.1 - 0.0053 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase betaPIX_CC PF16523.5 ORY06313.1 - 0.01 15.6 1.6 0.021 14.6 1.6 1.4 1 0 0 1 1 1 0 betaPIX coiled coil ZapB PF06005.12 ORY06313.1 - 0.7 10.4 7.9 0.082 13.4 1.4 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Peptidase_S9 PF00326.21 ORY06314.1 - 7.4e-51 172.6 0.0 1.1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ORY06314.1 - 6.9e-08 32.3 0.0 1.9e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ORY06314.1 - 1.3e-05 24.0 0.4 0.0027 16.4 0.1 2.8 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ORY06314.1 - 2.9e-05 24.0 0.3 0.00034 20.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY06314.1 - 3.5e-05 23.5 0.1 0.21 11.1 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 ORY06314.1 - 0.00029 20.4 0.0 0.00065 19.3 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase DPPIV_N PF00930.21 ORY06314.1 - 0.0006 18.7 0.9 1 8.0 0.1 3.4 3 1 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Esterase PF00756.20 ORY06314.1 - 0.007 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PD40 PF07676.12 ORY06314.1 - 0.017 15.0 0.9 0.12 12.3 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2920 PF11144.8 ORY06314.1 - 0.018 14.3 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) COesterase PF00135.28 ORY06314.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_1 PF00561.20 ORY06314.1 - 0.051 13.2 0.5 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Ig_6 PF18452.1 ORY06314.1 - 0.11 12.1 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain UQ_con PF00179.26 ORY06315.1 - 8.8e-45 151.8 0.1 1.1e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 ORY06315.1 - 5e-12 45.5 0.1 9.7e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 ORY06315.1 - 8.2e-05 22.3 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY06315.1 - 0.024 14.9 0.1 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ORY06315.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF1296 PF06972.11 ORY06315.1 - 0.19 11.9 0.6 0.59 10.3 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) Bac_globin PF01152.21 ORY06316.1 - 3.4e-07 30.4 0.1 4.8e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial-like globin PAS PF00989.25 ORY06317.1 - 4.3e-12 46.0 0.1 1.3e-06 28.4 0.1 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ORY06317.1 - 1e-08 35.3 0.0 0.0063 16.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ORY06317.1 - 6.2e-08 32.9 0.0 0.0004 20.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ORY06317.1 - 3.9e-07 30.3 0.0 0.00018 21.7 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_12 PF18095.1 ORY06317.1 - 4.1e-05 23.3 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 2 UPF0242 C-terminal PAS-like domain PAS_2 PF08446.11 ORY06317.1 - 5.2e-05 23.9 0.0 0.072 13.8 0.0 2.5 2 1 0 2 2 2 2 PAS fold PAS_11 PF14598.6 ORY06317.1 - 0.025 14.7 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 PAS domain SPRY PF00622.28 ORY06318.1 - 3.7e-13 49.6 0.1 6.1e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.32 ORY06319.1 - 3e-38 129.1 22.4 2.2e-08 34.6 0.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY06319.1 - 4.9e-12 46.0 0.5 0.023 15.0 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY06319.1 - 3.3e-10 39.8 2.4 9.6e-08 31.7 0.1 3.1 2 1 1 3 3 3 2 WD40-like domain DUF5046 PF16465.5 ORY06319.1 - 2.5e-06 27.2 0.2 0.0067 15.9 0.0 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 ORY06319.1 - 0.0033 16.4 1.3 0.038 12.9 0.1 2.9 1 1 3 4 4 4 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 ORY06319.1 - 0.0079 16.1 0.0 0.16 11.8 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.31 ORY06320.1 - 1.4e-18 66.8 3.2 2.7e-09 37.1 0.8 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY06320.1 - 7.2e-16 58.2 2.6 1.5e-08 34.8 0.2 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY06320.1 - 0.036 14.1 0.1 0.12 12.5 0.0 1.8 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RPA_C PF08784.11 ORY06321.1 - 4.9e-15 56.1 0.0 1.1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 ORY06321.1 - 1.9e-05 24.5 0.3 3.2e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 ORY06321.1 - 0.0032 17.3 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 GIDE PF12483.8 ORY06322.1 - 9.1e-13 47.9 0.0 1.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.6 ORY06322.1 - 1.2e-11 44.3 8.6 1.6e-11 43.8 8.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY06322.1 - 0.00024 20.9 8.9 0.00039 20.2 8.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY06322.1 - 0.0011 19.2 11.3 0.0018 18.6 11.3 1.3 1 0 0 1 1 1 1 Ring finger domain tRNA_anti-codon PF01336.25 ORY06322.1 - 0.15 12.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain zf-C3HC4 PF00097.25 ORY06322.1 - 0.15 11.9 12.2 0.24 11.3 12.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY06322.1 - 0.43 10.5 12.1 0.68 9.8 12.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY06322.1 - 2 8.5 10.2 3.2 7.8 10.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Tnp_zf-ribbon_2 PF13842.6 ORY06322.1 - 2.8 8.8 9.4 5.5 7.9 9.4 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Gln-synt_C PF00120.24 ORY06323.1 - 2.9e-67 227.1 0.0 3.9e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Myb_DNA-bind_4 PF13837.6 ORY06323.1 - 2.7e-12 46.9 0.2 5.6e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY06323.1 - 4.5e-05 23.6 0.3 0.00012 22.2 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY06323.1 - 7.9e-05 22.8 0.6 0.00022 21.3 0.6 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY06323.1 - 0.0023 18.2 0.0 0.0061 16.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 ORY06323.1 - 0.036 14.1 1.2 0.09 12.9 1.2 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Spore_III_AF PF09581.10 ORY06324.1 - 0.044 13.8 0.5 0.051 13.6 0.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ras PF00071.22 ORY06325.1 - 1.7e-54 183.8 0.0 1.9e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY06325.1 - 1e-21 77.4 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY06325.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY06325.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY06325.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PRELI PF04707.14 ORY06326.1 - 2.5e-46 157.4 0.0 3e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family PP2C PF00481.21 ORY06327.1 - 1.2e-44 152.9 0.0 1.6e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY06327.1 - 0.00018 21.2 0.0 0.00041 20.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ORY06327.1 - 0.00035 20.6 0.2 1.4 8.8 0.0 3.3 2 2 1 3 3 3 2 Stage II sporulation protein E (SpoIIE) WD-3 PF09765.9 ORY06328.1 - 1.2e-32 113.4 0.3 1.5e-32 113.1 0.3 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 ORY06328.1 - 5.2e-29 100.2 3.2 8.2e-29 99.6 3.2 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 ORY06328.1 - 2.5e-06 27.7 4.3 2.5e-06 27.7 4.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY06328.1 - 0.0071 16.6 3.6 0.02 15.1 3.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY06328.1 - 0.015 15.3 3.6 0.026 14.6 2.3 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 ORY06328.1 - 0.016 15.5 0.2 0.025 14.8 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 ORY06328.1 - 0.017 15.4 1.9 0.066 13.5 1.9 2.0 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 ORY06328.1 - 0.077 13.1 2.0 0.16 12.1 2.0 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 ORY06328.1 - 0.17 11.8 3.3 0.77 9.7 0.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 ORY06328.1 - 0.17 11.8 4.1 0.4 10.6 4.1 1.7 1 1 0 1 1 1 0 PHD-finger PLDc_2 PF13091.6 ORY06329.1 - 6.5e-19 68.1 0.3 5.9e-09 35.9 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 ORY06329.1 - 1.5e-14 53.5 7.4 1e-06 28.6 0.1 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif D123 PF07065.14 ORY06330.1 - 1.6e-104 349.3 0.5 1.9e-104 349.1 0.5 1.0 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 ORY06330.1 - 0.0045 16.8 0.1 0.0075 16.1 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 ORY06330.1 - 0.035 14.1 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Transket_pyr PF02779.24 ORY06331.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain LPMO_10 PF03067.15 ORY06332.1 - 4.3e-05 24.2 0.1 0.00044 21.0 0.0 2.4 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY06332.1 - 0.002 18.1 0.0 0.029 14.3 0.0 2.6 1 1 2 3 3 3 1 Glycosyl hydrolase family 61 Trypan_PARP PF05887.11 ORY06332.1 - 0.28 11.2 9.5 0.47 10.4 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBM_14 PF01607.24 ORY06332.1 - 1.8 8.8 6.7 1.4 9.2 4.4 2.1 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Sugar_tr PF00083.24 ORY06333.1 - 3.6e-59 200.8 22.0 4.3e-59 200.6 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY06333.1 - 8.1e-29 100.6 25.6 3.2e-28 98.7 24.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY06333.1 - 4.6e-07 29.5 2.5 9.2e-07 28.5 2.5 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORY06333.1 - 0.0003 19.5 11.6 0.0003 19.5 11.6 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORY06333.1 - 0.001 18.7 1.3 0.0083 15.7 0.7 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORY06333.1 - 0.28 9.4 9.1 0.13 10.5 3.0 2.8 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_molyb PF00174.19 ORY06334.1 - 2e-55 187.0 0.0 2.7e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY06334.1 - 5.6e-31 107.4 0.0 8.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 ORY06334.1 - 0.0022 18.7 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial Ig domain RNHCP PF12647.7 ORY06334.1 - 0.015 15.2 0.1 7.4 6.6 0.1 2.9 3 0 0 3 3 3 0 RNHCP domain NAP PF00956.18 ORY06335.1 - 3.2e-28 98.7 21.9 1.8e-22 79.8 11.7 4.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Ribosomal_L29 PF00831.23 ORY06337.1 - 2.9e-21 75.2 3.4 2.9e-21 75.2 3.4 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 ORY06337.1 - 0.035 14.5 2.4 0.035 14.5 2.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin T3SS_needle_E PF08988.10 ORY06337.1 - 1.2 9.3 4.4 20 5.4 0.2 2.5 2 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Prefoldin PF02996.17 ORY06337.1 - 1.8 8.5 9.8 4.7 7.1 1.7 2.9 2 1 1 3 3 3 0 Prefoldin subunit Snf7 PF03357.21 ORY06337.1 - 2.8 7.5 12.4 2.4 7.7 1.0 2.1 1 1 1 2 2 2 0 Snf7 Ribosomal_L15e PF00827.17 ORY06338.1 - 1.4e-90 302.1 9.7 1.7e-90 301.9 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 TatD_DNase PF01026.21 ORY06339.1 - 1.3e-58 198.4 0.3 1.5e-58 198.2 0.3 1.0 1 0 0 1 1 1 1 TatD related DNase PDZ_3 PF17815.1 ORY06339.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 PDZ domain DUF5527 PF17665.1 ORY06339.1 - 0.15 11.6 0.9 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5527) S10_plectin PF03501.15 ORY06340.1 - 1.6e-47 159.5 0.1 1.9e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 ORY06340.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 ORY06340.1 - 0.077 13.0 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Kinase-like PF14531.6 ORY06340.1 - 0.081 12.2 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF4364 PF14277.6 ORY06340.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF2250 PF10007.9 ORY06340.1 - 0.19 11.8 1.0 4.2 7.5 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Cyclin PF08613.11 ORY06341.1 - 1.1e-07 32.4 0.4 1.9e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin ADAM_CR PF08516.12 ORY06341.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 ADAM cysteine-rich CH PF00307.31 ORY06342.1 - 1.2e-09 38.3 0.6 1.9e-09 37.7 0.6 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.17 ORY06342.1 - 1.7e-06 28.1 0.4 4.1e-06 26.9 0.4 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif SlyX PF04102.12 ORY06342.1 - 0.0019 18.8 0.9 0.0047 17.5 0.9 1.7 1 0 0 1 1 1 1 SlyX Suppressor_APC PF11414.8 ORY06342.1 - 0.0022 18.0 1.2 0.0037 17.3 0.4 1.8 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein CH_2 PF06294.11 ORY06342.1 - 0.0052 16.9 1.0 0.0096 16.0 1.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein APG6_N PF17675.1 ORY06342.1 - 0.063 13.8 0.5 0.13 12.8 0.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 ORY06342.1 - 0.32 11.3 2.3 0.31 11.4 0.6 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family WD40 PF00400.32 ORY06343.1 - 1.3e-35 120.8 22.3 8.1e-08 32.8 0.9 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 ORY06343.1 - 8.4e-15 54.4 8.6 0.00013 20.8 0.0 5.2 3 2 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY06343.1 - 9.6e-11 41.5 0.1 0.00055 19.4 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 ORY06343.1 - 4.4e-09 36.5 0.9 0.029 14.7 0.0 5.7 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORY06343.1 - 5.8e-06 26.3 0.1 0.0037 17.3 0.0 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 ORY06343.1 - 0.00039 19.3 0.3 0.13 11.0 0.1 3.6 3 1 1 4 4 4 1 Nup133 N terminal like DUF3450 PF11932.8 ORY06343.1 - 0.0016 17.8 3.7 0.003 16.9 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PALB2_WD40 PF16756.5 ORY06343.1 - 0.0088 15.0 3.5 0.59 9.0 0.2 3.8 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain DUF812 PF05667.11 ORY06343.1 - 0.0096 14.9 4.7 0.012 14.6 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF4200 PF13863.6 ORY06343.1 - 0.076 13.4 7.4 0.13 12.7 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) BRE1 PF08647.11 ORY06343.1 - 0.38 10.9 9.8 0.69 10.0 8.2 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Ge1_WD40 PF16529.5 ORY06343.1 - 0.58 9.1 4.3 1.7 7.5 0.1 3.3 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CSRNP_N PF16019.5 ORY06343.1 - 1.3 8.9 5.2 2.3 8.1 5.2 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus APG6_N PF17675.1 ORY06343.1 - 3.4 8.2 15.6 2.3 8.8 11.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-C2H2 PF00096.26 ORY06344.1 - 3.1e-12 46.2 15.4 2e-06 27.9 3.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY06344.1 - 4.7e-08 33.2 11.6 0.00018 22.0 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY06344.1 - 1.8e-06 28.1 4.2 1.8e-06 28.1 4.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY06344.1 - 5.3e-05 23.1 1.3 5.3e-05 23.1 1.3 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY06344.1 - 0.001 18.8 11.1 0.043 13.6 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-met PF12874.7 ORY06344.1 - 0.0017 18.7 3.4 1 9.9 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ORY06344.1 - 0.0029 18.3 4.6 0.0075 16.9 4.6 1.7 1 1 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORY06344.1 - 0.013 15.7 2.5 0.81 9.8 0.2 2.0 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY06344.1 - 0.013 15.8 0.5 0.03 14.6 0.5 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 ORY06344.1 - 0.029 14.7 5.6 0.67 10.3 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CHORD PF04968.12 ORY06344.1 - 0.04 14.6 2.0 4 8.2 0.3 2.1 1 1 1 2 2 2 0 CHORD FOXP-CC PF16159.5 ORY06344.1 - 0.05 14.2 1.5 4.9 7.9 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain ADD_ATRX PF17981.1 ORY06344.1 - 0.16 11.9 3.2 1.4 8.9 0.2 2.0 1 1 1 2 2 2 0 Cysteine Rich ADD domain zf-C2H2_jaz PF12171.8 ORY06344.1 - 2.5 8.5 9.1 0.82 10.0 0.4 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORY06345.1 - 2e-14 53.2 9.6 5.4e-07 29.7 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY06345.1 - 1.7e-08 34.6 9.2 0.00057 20.5 0.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY06345.1 - 2.3e-06 27.7 2.1 2.3e-06 27.7 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain Ogr_Delta PF04606.12 ORY06345.1 - 0.00078 19.4 1.0 0.48 10.5 0.0 2.2 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_aberr PF17017.5 ORY06345.1 - 0.011 15.9 5.4 0.5 10.5 0.7 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 ORY06345.1 - 0.021 15.5 3.3 0.14 12.8 0.0 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain Toxin_8 PF07365.12 ORY06345.1 - 0.14 12.3 1.7 0.17 12.1 0.2 1.8 1 1 1 2 2 2 0 Alpha conotoxin precursor SpdB PF05122.13 ORY06345.1 - 0.45 10.7 6.4 2.2 8.5 0.3 2.3 2 1 0 2 2 2 0 Mobile element transfer protein ResIII PF04851.15 ORY06346.1 - 5.2e-23 81.9 0.2 1.8e-22 80.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY06346.1 - 2.3e-15 56.9 0.1 5.8e-14 52.4 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY06346.1 - 1.8e-11 44.1 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 ORY06346.1 - 2.6e-06 26.9 0.0 5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 ORY06346.1 - 3.9e-06 26.7 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 ORY06346.1 - 0.015 15.6 0.1 0.14 12.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 ORY06346.1 - 0.015 14.0 0.0 0.044 12.5 0.0 1.7 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_11 PF13086.6 ORY06346.1 - 0.097 12.4 4.8 0.14 11.9 0.1 2.7 2 1 1 3 3 3 0 AAA domain Pkinase PF00069.25 ORY06347.1 - 5.8e-63 212.7 0.0 7.6e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06347.1 - 7.8e-38 130.2 0.0 1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY06347.1 - 0.00012 21.5 0.0 0.00037 19.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 ORY06347.1 - 0.0083 15.2 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORY06347.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY06347.1 - 0.062 13.2 0.0 0.41 10.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family GATA PF00320.27 ORY06348.1 - 3.8e-29 100.0 17.2 2.2e-15 56.0 5.7 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 ORY06348.1 - 3.5e-12 45.9 2.4 1e-11 44.5 2.4 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 ORY06348.1 - 3.5e-07 29.6 4.7 0.0079 15.7 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY06348.1 - 0.0002 21.4 0.9 0.54 10.4 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORY06348.1 - 0.011 15.9 6.1 0.38 10.9 0.8 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ORY06348.1 - 0.02 14.8 6.2 0.4 10.6 0.5 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.13 ORY06348.1 - 0.022 14.8 3.4 2.8 8.1 0.1 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 ORY06348.1 - 0.07 13.2 6.3 1.1 9.4 6.4 2.7 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.21 ORY06348.1 - 0.33 11.1 6.6 5 7.3 0.3 3.0 3 0 0 3 3 3 0 FYVE zinc finger HypA PF01155.19 ORY06348.1 - 0.87 9.6 3.4 2.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 ORY06348.1 - 2.2 8.4 7.5 4.2 7.5 4.3 2.7 2 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type OrfB_Zn_ribbon PF07282.11 ORY06348.1 - 4.1 7.4 7.8 23 5.0 0.5 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_15 PF17032.5 ORY06348.1 - 4.5 8.1 7.7 8.9 7.1 1.7 2.8 1 1 1 2 2 2 0 zinc-ribbon family Prefoldin_2 PF01920.20 ORY06349.1 - 1.6e-22 79.5 18.3 1.9e-22 79.2 18.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit DMPK_coil PF08826.10 ORY06349.1 - 0.00052 20.1 3.5 0.00052 20.1 3.5 2.3 2 0 0 2 2 1 1 DMPK coiled coil domain like DUF4164 PF13747.6 ORY06349.1 - 0.0024 18.1 9.3 0.016 15.4 1.7 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) DUF3375 PF11855.8 ORY06349.1 - 0.0061 15.5 1.8 0.0061 15.5 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3375) DUF1192 PF06698.11 ORY06349.1 - 0.13 12.3 7.0 0.097 12.7 3.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DivIC PF04977.15 ORY06349.1 - 0.15 11.8 16.5 1 9.2 8.6 2.6 2 1 0 2 2 2 0 Septum formation initiator ADIP PF11559.8 ORY06349.1 - 0.18 11.9 14.0 0.54 10.3 13.2 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 ORY06349.1 - 0.33 11.2 8.9 0.071 13.3 5.2 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 ORY06349.1 - 0.37 11.0 14.1 2.7 8.3 6.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SpecificRecomb PF10136.9 ORY06349.1 - 0.44 8.8 7.4 0.46 8.7 7.4 1.0 1 0 0 1 1 1 0 Site-specific recombinase FlxA PF14282.6 ORY06349.1 - 1.1 9.3 20.6 0.15 12.1 14.3 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF4298 PF14131.6 ORY06349.1 - 1.3 9.0 11.8 1.2 9.2 5.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) DUF1910 PF08928.10 ORY06349.1 - 2 8.5 8.4 0.51 10.4 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) FlaC_arch PF05377.11 ORY06349.1 - 2.4 8.6 10.5 7.4 7.1 4.4 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 ORY06349.1 - 2.6 8.4 17.4 2 8.7 10.6 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 ORY06349.1 - 3.5 6.9 10.4 6.5 6.0 10.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 ORY06349.1 - 4.6 7.8 14.9 25 5.4 14.9 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 ORY06349.1 - 5.1 7.3 14.3 13 6.0 14.3 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 ORY06349.1 - 6.8 7.4 16.3 8 7.2 9.1 2.1 1 1 0 2 2 2 0 Initiation control protein YabA RNA_pol_Rpb5_C PF01191.19 ORY06350.1 - 1.9e-33 114.2 0.2 4e-33 113.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 ORY06350.1 - 8.5e-33 112.8 0.1 1.6e-32 111.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 ORY06350.1 - 0.0065 16.5 0.0 0.02 14.9 0.0 1.9 1 1 1 2 2 2 1 Restriction endonuclease DUF4144 PF13642.6 ORY06350.1 - 0.045 14.3 0.1 4.3 8.0 0.1 2.2 2 0 0 2 2 2 0 protein structure with unknown function Xpo1 PF08389.12 ORY06351.1 - 3.5e-25 88.8 0.6 2.2e-23 82.9 0.1 3.4 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 ORY06351.1 - 1e-07 31.7 0.3 5.8e-07 29.3 0.4 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep PF18773.1 ORY06351.1 - 0.00048 19.8 0.3 0.00048 19.8 0.3 2.1 2 0 0 2 2 2 1 Importin 13 repeat DUF5424 PF17462.2 ORY06351.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5424) RraA-like PF03737.15 ORY06352.1 - 6.2e-34 117.3 0.2 7.4e-34 117.1 0.2 1.1 1 0 0 1 1 1 1 Aldolase/RraA GPI-anchored PF10342.9 ORY06354.1 - 0.16 12.8 1.5 0.23 12.3 1.4 1.4 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DPBB_1 PF03330.18 ORY06355.1 - 1.2e-09 38.4 0.0 2.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY06355.1 - 0.026 14.4 0.1 0.099 12.5 0.0 1.9 2 0 0 2 2 2 0 Barwin family DPBB_1 PF03330.18 ORY06356.1 - 1.4e-10 41.3 0.1 2.4e-10 40.6 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY06356.1 - 0.062 13.1 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Barwin family DUF3039 PF11238.8 ORY06356.1 - 0.09 12.5 1.4 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) DPBB_1 PF03330.18 ORY06358.1 - 1.6e-09 37.9 0.1 4.3e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY06358.1 - 0.078 12.8 0.2 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Barwin family CBM_14 PF01607.24 ORY06358.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.9 4 1 0 4 4 4 0 Chitin binding Peritrophin-A domain ABC_tran PF00005.27 ORY06359.1 - 8.9e-50 168.8 0.0 1.3e-27 96.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY06359.1 - 2.3e-15 57.2 0.4 0.0037 17.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY06359.1 - 4.9e-11 42.5 1.6 0.0041 16.6 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY06359.1 - 3.8e-08 34.1 2.5 0.014 15.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 ORY06359.1 - 1.9e-07 30.7 0.1 0.025 14.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain 4HB PF17947.1 ORY06359.1 - 1.7e-06 27.9 0.2 7.3e-06 26.0 0.2 2.1 1 0 0 1 1 1 1 Four helical bundle domain Chromo PF00385.24 ORY06359.1 - 3.4e-06 26.9 0.1 6.9e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 ORY06359.1 - 4.7e-06 26.9 0.0 0.054 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 ORY06359.1 - 6.2e-06 26.5 1.1 0.0014 18.7 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 ORY06359.1 - 1.7e-05 24.8 0.7 0.23 11.5 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY06359.1 - 2.1e-05 24.5 0.3 0.07 13.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 ORY06359.1 - 2.8e-05 23.8 0.0 0.2 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY06359.1 - 6e-05 23.6 0.1 0.71 10.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain HEAT PF02985.22 ORY06359.1 - 9.8e-05 22.3 0.8 0.013 15.7 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 ORY06359.1 - 0.00027 21.3 5.1 0.00092 19.6 0.1 3.9 4 1 0 4 4 4 1 HEAT repeats AAA_16 PF13191.6 ORY06359.1 - 0.00037 20.9 0.0 0.2 12.0 0.0 3.5 4 0 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY06359.1 - 0.00057 20.2 0.0 1.6 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 ORY06359.1 - 0.0014 18.6 0.4 0.43 10.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_15 PF13175.6 ORY06359.1 - 0.0016 18.3 3.3 1.1 8.8 0.1 3.2 2 1 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 ORY06359.1 - 0.0018 18.6 0.0 2.9 8.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 ORY06359.1 - 0.0044 17.2 0.0 2.8 8.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 ORY06359.1 - 0.0045 16.9 0.1 2.3 8.1 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain MeaB PF03308.16 ORY06359.1 - 0.006 15.6 0.4 2 7.3 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 ORY06359.1 - 0.0064 16.9 0.0 8 6.9 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY06359.1 - 0.0066 16.2 0.2 3.8 7.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain HEAT_EZ PF13513.6 ORY06359.1 - 0.01 16.4 6.6 8.7 7.0 0.1 5.0 4 1 1 5 5 5 0 HEAT-like repeat CLASP_N PF12348.8 ORY06359.1 - 0.011 15.2 0.0 0.15 11.6 0.0 2.3 1 1 0 1 1 1 0 CLASP N terminal DUF815 PF05673.13 ORY06359.1 - 0.012 14.8 0.1 2.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 ORY06359.1 - 0.019 13.6 0.1 2.2 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Vac14_Fab1_bd PF12755.7 ORY06359.1 - 0.021 15.4 0.0 12 6.6 0.0 3.3 4 0 0 4 4 2 0 Vacuolar 14 Fab1-binding region MukB PF04310.12 ORY06359.1 - 0.023 14.5 0.4 4 7.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_24 PF13479.6 ORY06359.1 - 0.027 14.2 0.2 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.20 ORY06359.1 - 0.05 12.2 2.2 0.1 11.1 2.2 1.5 1 0 0 1 1 1 0 Adaptin N terminal region AAA_7 PF12775.7 ORY06359.1 - 0.051 13.1 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Cnd1 PF12717.7 ORY06359.1 - 0.059 13.4 0.2 0.25 11.4 0.1 2.1 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 SbcCD_C PF13558.6 ORY06359.1 - 0.07 13.4 0.0 8.5 6.7 0.0 3.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Arm PF00514.23 ORY06359.1 - 0.072 13.2 0.2 2.1 8.5 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Zeta_toxin PF06414.12 ORY06359.1 - 0.073 12.3 0.3 9.7 5.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF3584 PF12128.8 ORY06359.1 - 0.074 10.6 1.3 1.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) G-alpha PF00503.20 ORY06359.1 - 0.11 11.6 0.0 9.1 5.3 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 ORY06359.1 - 0.12 12.6 0.1 28 4.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ParcG PF10274.9 ORY06359.1 - 0.47 10.6 2.0 4.2 7.4 0.0 2.8 1 1 1 3 3 3 0 Parkin co-regulated protein NmrA PF05368.13 ORY06360.1 - 2.6e-23 82.8 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY06360.1 - 1.6e-16 60.8 0.0 2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORY06360.1 - 7.9e-09 35.9 0.1 2.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORY06360.1 - 2.7e-06 27.0 0.1 4.9e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY06360.1 - 7.4e-05 22.8 0.3 0.0039 17.2 0.0 2.6 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 ORY06360.1 - 0.059 12.8 0.1 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 ORY06360.1 - 0.11 12.9 1.1 3 8.3 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Lipoprot_C PF08794.10 ORY06360.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like Sugar_tr PF00083.24 ORY06361.1 - 8.6e-51 173.2 18.2 1e-36 126.8 5.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY06361.1 - 1.1e-23 83.8 21.5 7.9e-23 80.9 19.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY06361.1 - 4e-07 29.7 2.5 7.8e-07 28.7 2.5 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORY06361.1 - 0.00026 19.7 11.6 0.00026 19.7 11.6 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein OATP PF03137.20 ORY06361.1 - 0.015 13.6 3.4 0.03 12.6 0.6 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Copine PF07002.16 ORY06425.1 - 3.3e-61 206.5 0.1 4.3e-61 206.1 0.1 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 ORY06425.1 - 3.5e-05 24.0 0.0 6.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 ORY06425.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.7 1 1 0 1 1 1 1 vWA found in TerF C terminus Mcl1_mid PF12341.8 ORY06425.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Inv-AAD PF18785.1 ORY06426.1 - 5.4e-35 120.1 0.7 7.5e-34 116.4 0.7 2.0 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORY06426.1 - 6.9e-19 67.6 0.2 9.5e-19 67.2 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY06426.1 - 1.7e-06 27.8 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 ORY06426.1 - 0.003 17.5 0.1 0.0035 17.2 0.1 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Pkinase PF00069.25 ORY06427.1 - 7.3e-73 245.2 0.0 1.1e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06427.1 - 8.2e-33 113.8 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY06427.1 - 2.3e-09 37.0 0.0 3.6e-08 33.1 0.0 2.5 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 ORY06427.1 - 7.5e-06 26.0 0.0 0.0017 18.4 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY06427.1 - 1.9e-05 24.1 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY06427.1 - 0.00029 19.7 0.6 0.00073 18.4 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY06427.1 - 0.0036 16.3 0.2 0.0053 15.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY06427.1 - 0.018 14.7 0.1 0.99 9.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 ORY06427.1 - 0.054 13.0 0.2 0.12 11.9 0.1 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DnaJ_C PF01556.18 ORY06428.1 - 6e-39 133.5 0.1 8.2e-39 133.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY06428.1 - 1.6e-26 92.2 5.4 2.6e-26 91.5 5.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY06428.1 - 5.3e-11 42.7 18.0 9e-11 42.0 18.0 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF2318 PF10080.9 ORY06428.1 - 0.98 9.6 5.3 0.94 9.6 3.6 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 ORY06428.1 - 4.9 7.2 8.6 10 6.2 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ORY06428.1 - 5.3 7.1 19.0 0.088 12.8 5.8 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein UCH PF00443.29 ORY06429.1 - 1.2e-53 182.2 0.5 2.8e-53 181.1 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY06429.1 - 2.8e-26 92.9 2.1 2.8e-26 92.9 2.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.10 ORY06429.1 - 0.072 13.2 1.0 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Arrestin_N PF00339.29 ORY06430.1 - 1.4e-07 31.7 0.0 4.2e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY06430.1 - 3.7e-07 30.7 0.0 7.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY06430.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like RasGEF PF00617.19 ORY06431.1 - 7.6e-07 29.5 0.1 1e-06 29.0 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain Epsilon_antitox PF08998.11 ORY06431.1 - 0.066 13.5 0.2 0.22 11.8 0.2 1.8 1 1 1 2 2 2 0 Bacterial epsilon antitoxin N-glycanase_N PF09112.10 ORY06431.1 - 0.098 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal CxC4 PF18717.1 ORY06432.1 - 0.087 12.7 0.0 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases RasGEF PF00617.19 ORY06432.1 - 0.12 12.5 0.1 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 RasGEF domain G-gamma PF00631.22 ORY06433.1 - 1.7e-18 66.4 0.0 2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain RasGEF PF00617.19 ORY06436.1 - 3e-38 131.8 0.0 3.7e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain Imm26 PF15428.6 ORY06436.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 26 Yae1_N PF09811.9 ORY06438.1 - 3e-07 30.0 1.3 4.4e-07 29.5 1.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal TENA_THI-4 PF03070.16 ORY06439.1 - 8.7e-20 71.4 0.7 1.4e-09 38.1 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family NKAP PF15692.5 ORY06439.1 - 0.083 13.6 2.6 0.17 12.6 0.2 2.1 2 0 0 2 2 2 0 NF-kappa-B-activating protein 2-oxoacid_dh PF00198.23 ORY06440.1 - 1.1e-21 77.4 0.0 8.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Ribosomal_L23eN PF03939.13 ORY06441.1 - 5.7e-24 84.1 7.9 9.7e-24 83.3 7.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORY06441.1 - 1.3e-13 51.1 3.4 1.3e-13 51.1 0.4 2.4 2 2 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 ORY06441.1 - 0.0018 18.6 1.0 0.0021 18.4 1.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) TPR_19 PF14559.6 ORY06442.1 - 1e-11 45.2 2.9 0.0012 19.3 0.1 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY06442.1 - 1.5e-09 37.2 4.2 0.0037 17.3 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY06442.1 - 3.8e-09 36.6 2.4 0.072 14.0 0.0 4.7 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY06442.1 - 2.3e-06 28.1 0.1 0.00072 20.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY06442.1 - 2.8e-06 26.9 3.9 0.027 14.3 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY06442.1 - 4.2e-05 23.4 3.2 3.9 7.9 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY06442.1 - 0.0024 18.4 2.0 1.9 9.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY06442.1 - 0.059 13.5 0.5 0.66 10.2 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY06442.1 - 0.06 12.7 1.0 15 4.8 0.1 2.9 1 1 2 3 3 3 0 MalT-like TPR region PknG_TPR PF16918.5 ORY06442.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 ORY06442.1 - 0.68 10.2 5.1 3.5 7.9 0.4 2.6 1 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4874 PF16173.5 ORY06443.1 - 0.34 10.6 2.6 0.48 10.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) DUF4196 PF13846.6 ORY06443.1 - 0.59 10.4 4.4 1.1 9.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) FUSC PF04632.12 ORY06443.1 - 3 6.3 8.5 3.8 5.9 8.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sulfate_transp PF00916.20 ORY06444.1 - 3.5e-81 272.9 17.3 4.6e-81 272.5 17.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY06444.1 - 1.6e-11 43.9 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY06444.1 - 0.041 14.2 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 STAS domain Na_H_antiport_2 PF13726.6 ORY06444.1 - 0.17 12.1 6.6 0.15 12.2 1.1 3.1 2 1 0 2 2 2 0 Na+-H+ antiporter family DUF2304 PF10066.9 ORY06444.1 - 1.4 9.2 6.7 4.2 7.6 1.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MatE PF01554.18 ORY06445.1 - 3.2e-47 160.2 34.2 1e-25 90.3 11.0 3.1 3 0 0 3 3 3 2 MatE DEAD PF00270.29 ORY06446.1 - 4.8e-42 143.7 0.1 7e-42 143.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY06446.1 - 9.5e-27 93.5 1.3 2e-26 92.5 0.4 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 ORY06446.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GTP_EFTU PF00009.27 ORY06447.1 - 1.7e-37 128.8 0.3 5.8e-37 127.1 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY06447.1 - 1.5e-30 105.4 1.0 5.3e-30 103.6 1.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ORY06447.1 - 2.5e-08 34.0 0.4 6.6e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORY06447.1 - 4.9e-06 26.8 5.3 0.00086 19.6 0.1 3.1 3 0 0 3 3 2 2 Elongation factor Tu domain 2 IF2_N PF04760.15 ORY06447.1 - 3e-05 23.8 0.4 3e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 ORY06447.1 - 0.00012 21.6 0.1 0.00061 19.3 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY06447.1 - 0.00021 21.3 0.7 0.047 13.6 0.1 2.9 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 ORY06447.1 - 0.0066 15.9 0.6 0.096 12.1 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 ORY06447.1 - 0.0069 16.4 0.1 0.031 14.3 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 ORY06447.1 - 0.0086 16.1 1.6 3.4 7.7 0.0 3.3 3 0 0 3 3 3 1 Dynamin family PduV-EutP PF10662.9 ORY06447.1 - 0.011 15.5 0.2 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 ORY06447.1 - 0.023 15.2 0.9 3.3 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY06447.1 - 0.027 14.7 0.0 0.08 13.2 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 ORY06447.1 - 0.027 14.4 6.1 1.8 8.5 0.5 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 4 SRPRB PF09439.10 ORY06447.1 - 0.64 9.4 7.7 0.29 10.5 0.2 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit LMBR1 PF04791.16 ORY06448.1 - 3.3e-24 85.7 31.9 7.6e-23 81.2 31.9 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF5305 PF17231.2 ORY06448.1 - 0.23 10.8 1.1 0.41 10.0 0.1 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5305) Aminotran_5 PF00266.19 ORY06449.1 - 2.9e-30 105.5 0.0 3.8e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 ORY06449.1 - 1.4e-05 25.1 0.4 0.0015 18.6 0.0 2.8 2 1 0 2 2 2 1 B12 binding domain Cys_Met_Meta_PP PF01053.20 ORY06449.1 - 6.3e-05 21.7 0.0 9.6e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme adh_short_C2 PF13561.6 ORY06449.1 - 0.026 14.1 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06449.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 KR domain Glyco_hydro_46 PF01374.18 ORY06450.1 - 3.7e-34 118.2 0.0 4.2e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 E1-E2_ATPase PF00122.20 ORY06451.1 - 3e-53 180.1 0.2 3e-53 180.1 0.2 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY06451.1 - 2.5e-44 151.2 1.6 2.5e-44 151.2 1.6 2.9 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY06451.1 - 3.3e-23 83.1 0.0 1.5e-22 81.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY06451.1 - 2.5e-16 59.1 0.6 4.5e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY06451.1 - 3e-16 59.3 0.0 9.2e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY06451.1 - 9.8e-05 22.2 2.8 0.0015 18.4 1.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY06451.1 - 0.03 14.7 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PknG_TPR PF16918.5 ORY06451.1 - 0.1 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat DUF3784 PF12650.7 ORY06451.1 - 1.2 9.3 13.3 0.27 11.5 0.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Dcc1 PF09724.9 ORY06452.1 - 6e-80 269.0 0.1 6.8e-80 268.9 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 YL1_C PF08265.11 ORY06453.1 - 7.7e-16 57.6 0.2 1.1e-15 57.1 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 ORY06453.1 - 0.052 13.4 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger PDT PF00800.18 ORY06454.1 - 9.9e-44 149.3 0.0 1.3e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ORY06454.1 - 1.5e-07 31.0 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain Sulfotransfer_4 PF17784.1 ORY06455.1 - 1.2e-62 211.6 1.6 4.3e-62 209.7 1.6 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY06455.1 - 0.00032 21.1 0.0 0.00083 19.8 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 ORY06456.1 - 2.8e-68 229.9 0.1 3.3e-68 229.8 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY06456.1 - 4e-05 24.1 0.0 7.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family MARVEL PF01284.23 ORY06457.1 - 0.085 12.9 10.1 0.12 12.4 10.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain RNase_T PF00929.24 ORY06458.1 - 1.7e-17 64.5 0.1 4e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.22 ORY06458.1 - 9.4e-08 31.8 0.0 2.5e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S8 PF00082.22 ORY06459.1 - 2.3e-34 119.0 6.3 6.4e-34 117.6 6.3 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY06459.1 - 0.0072 17.0 0.0 0.021 15.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 Fungal_trans PF04082.18 ORY06460.1 - 7.3e-25 87.5 0.5 7.3e-25 87.5 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY06460.1 - 5.4e-10 39.2 13.6 1.1e-09 38.2 13.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.21 ORY06461.1 - 4.2e-167 557.0 0.0 4.9e-167 556.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G-patch PF01585.23 ORY06462.1 - 2e-10 40.4 0.7 5.6e-10 39.0 0.7 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 ORY06462.1 - 8.2e-10 38.5 0.1 1.6e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 ORY06462.1 - 9.3e-06 25.6 1.1 1.7e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 G-patch domain IMS PF00817.20 ORY06463.1 - 1e-43 148.9 0.0 3.6e-43 147.2 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ORY06463.1 - 6.8e-14 52.6 0.0 2e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 ORY06463.1 - 1.3e-08 35.1 0.0 2.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY06463.1 - 3.3e-07 30.6 0.0 7.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY06463.1 - 2.3e-06 27.5 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 ORY06463.1 - 8.5e-05 22.8 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 ORY06463.1 - 0.0002 21.5 0.3 0.00066 19.9 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif UBM PF14377.6 ORY06463.1 - 0.00028 20.2 0.7 0.37 10.3 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin binding region DUF1805 PF08827.11 ORY06463.1 - 0.095 13.1 0.0 1.2 9.5 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1805) GPR_Gpa2_C PF11970.8 ORY06464.1 - 1.9 8.6 5.5 0.7 10.0 0.1 3.0 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term AdoHcyase PF05221.17 ORY06465.1 - 4.7e-135 449.5 0.0 4.5e-74 249.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ORY06465.1 - 1e-85 285.7 4.1 1.5e-85 285.2 4.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY06465.1 - 5.3e-08 32.4 0.4 1.1e-07 31.4 0.4 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORY06465.1 - 2.2e-05 24.1 0.3 3.6e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ORY06465.1 - 0.0053 17.0 0.1 0.011 15.9 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.6 ORY06465.1 - 0.074 13.5 0.3 0.13 12.7 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein MRP-L20 PF12824.7 ORY06466.1 - 1.1e-24 87.5 1.5 1.2e-24 87.3 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 CtsR PF05848.11 ORY06466.1 - 0.072 13.0 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 CtsR N-terminal HTH domain HTH_11 PF08279.12 ORY06466.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 HTH domain Arm PF00514.23 ORY06467.1 - 3e-33 112.8 32.1 2.1e-08 33.9 0.0 10.8 12 0 0 12 12 12 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY06467.1 - 2.5e-12 47.0 6.6 0.011 16.1 0.0 7.5 5 2 4 9 9 9 4 HEAT repeats HEAT PF02985.22 ORY06467.1 - 4.7e-09 35.7 21.1 0.15 12.4 0.1 10.0 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 ORY06467.1 - 1.2e-08 35.2 19.5 0.15 12.6 0.6 8.7 8 0 0 8 8 8 2 HEAT-like repeat DUF3361 PF11841.8 ORY06467.1 - 6.4e-06 26.2 6.7 0.0044 17.0 0.2 4.1 3 1 1 4 4 4 2 Domain of unknown function (DUF3361) Cnd1 PF12717.7 ORY06467.1 - 0.00019 21.5 9.1 0.054 13.5 0.2 4.9 3 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 ORY06467.1 - 0.00045 20.2 12.3 0.29 11.2 0.0 6.5 6 2 2 8 8 8 2 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 ORY06467.1 - 0.014 15.5 4.8 4.6 7.4 0.0 4.5 3 2 1 4 4 4 0 V-ATPase subunit H Vps39_1 PF10366.9 ORY06467.1 - 0.037 14.3 0.7 0.27 11.5 0.3 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 RTP1_C1 PF10363.9 ORY06467.1 - 0.27 11.4 5.4 6.2 7.0 0.1 4.3 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Sld7_C PF18596.1 ORY06468.1 - 1.7e-07 31.2 0.1 2.6e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Sld7 C-terminal domain MTBP_C PF14920.6 ORY06468.1 - 0.00064 19.6 0.0 0.0007 19.4 0.0 1.1 1 0 0 1 1 1 1 MDM2-binding ATP-synt_F PF01990.17 ORY06469.1 - 2.4e-32 111.1 0.2 2.8e-32 110.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 ORY06469.1 - 0.019 14.2 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Rad21_Rec8_N PF04825.13 ORY06469.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Pribosyl_synth PF14572.6 ORY06472.1 - 4.4e-46 157.2 0.4 1.8e-37 129.2 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY06472.1 - 1.1e-36 125.3 0.0 6.7e-35 119.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY06472.1 - 5.1e-14 52.1 0.2 1e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_17 PF00332.18 ORY06474.1 - 1.6e-12 47.7 1.1 9.9e-08 31.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Insulin_TMD PF17870.1 ORY06474.1 - 0.03 14.4 1.1 0.061 13.4 1.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Phage_holin_3_3 PF16083.5 ORY06474.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III ARID PF01388.21 ORY06475.1 - 6.7e-16 58.7 0.0 2e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Katanin_con80 PF13925.6 ORY06475.1 - 0.089 12.8 4.8 0.85 9.6 0.7 2.6 3 0 0 3 3 3 0 con80 domain of Katanin Prenyltransf PF01255.19 ORY06477.1 - 5.4e-07 29.4 0.0 1.1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Type2_restr_D3 PF16902.5 ORY06477.1 - 0.21 11.5 0.4 1.9 8.5 0.4 2.2 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain CBS PF00571.28 ORY06480.1 - 1e-32 112.3 9.3 1.9e-07 31.4 0.0 6.0 6 1 1 7 7 7 4 CBS domain PB1 PF00564.24 ORY06480.1 - 9.3e-12 44.7 0.2 2.2e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 PB1 domain Membrane_bind PF14564.6 ORY06480.1 - 0.031 14.7 0.1 0.084 13.3 0.1 1.7 1 0 0 1 1 1 0 Membrane binding AbiEi_4 PF13338.6 ORY06480.1 - 0.16 12.2 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Glyco_hydro_15 PF00723.21 ORY06481.1 - 2e-63 214.7 0.0 9.5e-62 209.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 CSD PF00313.22 ORY06483.1 - 1.8e-22 79.0 0.1 3.1e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ORY06483.1 - 0.0048 16.5 0.1 0.0094 15.6 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain SUZ PF12752.7 ORY06484.1 - 1.4e-12 48.2 0.9 2.7e-12 47.3 0.9 1.5 1 0 0 1 1 1 1 SUZ domain BBP1_N PF15271.6 ORY06484.1 - 0.023 15.5 0.2 0.031 15.1 0.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Kinesin PF00225.23 ORY06485.1 - 1.5e-76 257.5 1.4 2e-76 257.1 1.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Methyltransf_16 PF10294.9 ORY06485.1 - 5e-13 49.2 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Microtub_bd PF16796.5 ORY06485.1 - 4.7e-12 46.1 0.0 1.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Methyltransf_25 PF13649.6 ORY06485.1 - 0.039 14.7 0.0 0.19 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Enterotoxin_b PF01376.18 ORY06485.1 - 0.064 13.4 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain Zeta_toxin PF06414.12 ORY06485.1 - 0.12 11.6 0.1 4.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Mito_carr PF00153.27 ORY06486.1 - 5.4e-44 148.0 4.0 1.7e-20 72.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IMPDH PF00478.25 ORY06549.1 - 3.2e-31 108.6 0.0 3.5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ORY06549.1 - 0.022 14.2 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase STIMATE PF12400.8 ORY06551.1 - 1.9e-30 106.0 2.7 2.3e-30 105.7 2.7 1.1 1 0 0 1 1 1 1 STIMATE family CsbD PF05532.12 ORY06552.1 - 0.0012 18.7 0.2 0.0013 18.6 0.2 1.1 1 0 0 1 1 1 1 CsbD-like PAP_assoc PF03828.19 ORY06553.1 - 4.2e-21 74.9 0.0 8.9e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY06553.1 - 1.4e-07 31.7 0.0 3.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain NHS PF15273.6 ORY06553.1 - 0.045 12.8 0.4 0.062 12.4 0.4 1.1 1 0 0 1 1 1 0 NHS-like LETM1 PF07766.13 ORY06554.1 - 2e-40 138.9 6.7 4.4e-39 134.5 6.7 2.0 1 1 0 1 1 1 1 LETM1-like protein AAA_23 PF13476.6 ORY06555.1 - 0.0016 19.0 3.9 0.0037 17.8 3.9 1.7 1 0 0 1 1 1 1 AAA domain TAF4 PF05236.14 ORY06555.1 - 0.0038 17.0 12.2 0.0071 16.1 12.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Borrelia_P83 PF05262.11 ORY06555.1 - 0.026 13.0 13.9 0.032 12.7 13.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SepF PF04472.12 ORY06555.1 - 0.037 14.3 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 Cell division protein SepF Draxin PF15550.6 ORY06555.1 - 0.11 12.3 9.4 0.18 11.6 9.4 1.3 1 0 0 1 1 1 0 Draxin EVC2_like PF12297.8 ORY06555.1 - 0.14 10.8 12.8 0.23 10.1 12.8 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CDC45 PF02724.14 ORY06555.1 - 0.24 9.6 10.0 0.31 9.3 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_11 PF13086.6 ORY06555.1 - 0.53 10.0 10.2 0.98 9.1 10.2 1.4 1 0 0 1 1 1 0 AAA domain DUF2048 PF09752.9 ORY06555.1 - 0.65 9.0 7.3 1 8.4 7.3 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF3027 PF11228.8 ORY06555.1 - 2 8.4 7.2 3.6 7.6 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF4407 PF14362.6 ORY06555.1 - 2.6 7.3 12.2 4.9 6.4 12.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 ORY06555.1 - 2.9 7.6 14.4 4.7 7.0 14.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 ORY06555.1 - 6.7 7.0 22.2 15 5.8 22.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Lung_7-TM_R PF06814.13 ORY06556.1 - 4.4e-10 39.3 16.7 5.7e-10 38.9 16.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor FtsK_4TM PF13491.6 ORY06556.1 - 3.1 7.5 8.8 21 4.8 7.9 2.6 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Amidohydro_2 PF04909.14 ORY06557.1 - 2.8e-08 33.9 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 ORY06557.1 - 3.4e-08 33.2 0.2 2.2e-07 30.5 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY06557.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.4 2 0 0 2 2 2 0 Amidohydrolase family CoA_binding_2 PF13380.6 ORY06557.1 - 0.16 12.5 0.1 5.9 7.4 0.0 2.5 1 1 0 2 2 2 0 CoA binding domain Ras PF00071.22 ORY06558.1 - 4.5e-53 179.2 0.0 5.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY06558.1 - 8.3e-19 68.0 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY06558.1 - 3.5e-06 26.6 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY06558.1 - 0.19 11.3 0.0 2.1 7.9 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Tubulin PF00091.25 ORY06559.1 - 3e-69 233.2 0.0 4.6e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY06559.1 - 4.8e-46 156.0 0.8 7.4e-46 155.4 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY06559.1 - 3.6e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4430 PF14478.6 ORY06559.1 - 0.035 14.7 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) CN_hydrolase PF00795.22 ORY06560.1 - 2.4e-13 50.1 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PHD PF00628.29 ORY06561.1 - 0.00056 19.8 3.5 0.001 18.9 3.5 1.5 1 0 0 1 1 1 1 PHD-finger TFIIE_alpha PF02002.17 ORY06561.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Fe_dep_repress PF01325.19 ORY06561.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 ORY06561.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding adh_short_C2 PF13561.6 ORY06562.1 - 3.6e-54 183.8 0.0 4.2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY06562.1 - 2.3e-52 177.3 0.0 3.3e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY06562.1 - 2.9e-09 37.1 0.0 5.6e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY06562.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY06562.1 - 0.086 12.3 0.2 2.3 7.6 0.2 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ORY06562.1 - 0.094 12.8 0.1 0.19 11.8 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_transf_3 PF02515.17 ORY06563.1 - 2.2e-109 366.0 0.0 2.8e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III PQ-loop PF04193.14 ORY06565.1 - 1.7e-36 123.8 15.2 1.2e-18 66.6 3.1 3.3 3 0 0 3 3 3 2 PQ loop repeat DUF1673 PF07895.11 ORY06565.1 - 0.12 12.0 2.0 0.21 11.3 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) ODC_AZ PF02100.17 ORY06567.1 - 6e-17 61.7 0.0 9.4e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Sec23_trunk PF04811.15 ORY06568.1 - 1e-72 244.6 0.0 1.5e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY06568.1 - 3.8e-28 97.3 0.2 8.1e-28 96.3 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY06568.1 - 7.5e-19 68.3 0.0 1.4e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY06568.1 - 9.2e-18 64.0 3.2 2.1e-17 62.9 3.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY06568.1 - 3.1e-07 30.2 0.0 7.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat GDP_Man_Dehyd PF16363.5 ORY06568.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Aldedh PF00171.22 ORY06569.1 - 1.4e-188 627.2 0.1 1.6e-188 627.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY06569.1 - 0.058 12.8 0.0 0.34 10.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) PseudoU_synth_1 PF01416.20 ORY06570.1 - 4.6e-33 113.9 0.0 2.5e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 ORY06570.1 - 0.015 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) UQ_con PF00179.26 ORY06571.1 - 1.9e-40 137.7 0.0 2.6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY06571.1 - 0.0074 16.6 0.3 0.011 16.0 0.3 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 ORY06571.1 - 0.11 12.3 0.3 0.19 11.6 0.3 1.4 1 1 0 1 1 1 0 UEV domain Perilipin PF03036.16 ORY06572.1 - 4.4e-11 42.4 0.6 5.9e-11 42.0 0.6 1.1 1 0 0 1 1 1 1 Perilipin family Carbpep_Y_N PF05388.11 ORY06572.1 - 0.003 18.1 0.0 0.004 17.7 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Perilipin PF03036.16 ORY06573.1 - 3.5e-13 49.4 0.5 3.5e-13 49.4 0.5 1.5 2 0 0 2 2 2 1 Perilipin family ApoO PF09769.9 ORY06573.1 - 0.0096 15.9 0.5 0.095 12.7 0.1 2.4 1 1 1 2 2 2 1 Apolipoprotein O DUSP PF06337.12 ORY06574.1 - 5.3e-15 55.8 0.1 1.2e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 DUSP domain zf-UBP PF02148.19 ORY06574.1 - 5.3e-12 45.9 8.7 5.3e-12 45.9 8.7 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein F-box PF00646.33 ORY06574.1 - 6.9e-12 44.9 2.6 2.6e-11 43.1 2.6 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY06574.1 - 2.9e-11 43.1 1.4 1.1e-10 41.2 1.4 2.1 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY06574.1 - 0.0086 16.0 0.6 0.0086 16.0 0.6 2.2 3 0 0 3 3 3 1 F-box Inositol_P PF00459.25 ORY06575.1 - 1.7e-57 195.0 0.2 2.5e-57 194.5 0.2 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Kelch_4 PF13418.6 ORY06576.1 - 2e-47 159.0 9.6 1.5e-07 31.3 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY06576.1 - 1.8e-44 149.1 7.7 1.6e-07 30.8 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ORY06576.1 - 1.2e-43 146.5 9.6 5.5e-09 35.8 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 ORY06576.1 - 7.2e-42 140.4 10.3 1e-07 32.0 0.1 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ORY06576.1 - 8.7e-42 140.7 11.0 4.7e-08 33.1 0.0 6.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY06576.1 - 3.9e-34 115.3 5.1 5.8e-06 26.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.6 ORY06576.1 - 0.022 15.2 7.8 31 5.2 0.0 5.6 5 1 1 6 6 6 0 PQQ-like domain AAA_18 PF13238.6 ORY06577.1 - 3.7e-08 34.0 0.0 7.9e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 ORY06577.1 - 5.8e-07 29.5 0.0 7.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORY06577.1 - 1.9e-06 28.1 0.0 9.2e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY06577.1 - 5.8e-05 23.5 0.0 7.8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 ORY06577.1 - 0.0001 21.7 0.0 0.00024 20.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 ORY06577.1 - 0.00015 22.1 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORY06577.1 - 0.00016 20.9 0.3 0.00047 19.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 ORY06577.1 - 0.00028 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 ORY06577.1 - 0.00086 18.5 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein dNK PF01712.19 ORY06577.1 - 0.0014 18.5 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_17 PF13207.6 ORY06577.1 - 0.0016 18.9 0.2 0.0047 17.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORY06577.1 - 0.0022 17.6 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 ORY06577.1 - 0.0026 17.8 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY06577.1 - 0.004 17.6 0.0 0.0072 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORY06577.1 - 0.0049 16.6 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY06577.1 - 0.0055 16.3 0.0 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region KAP_NTPase PF07693.14 ORY06577.1 - 0.0085 15.4 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NTPase_1 PF03266.15 ORY06577.1 - 0.009 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.20 ORY06577.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 ORY06577.1 - 0.011 15.5 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 ORY06577.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KTI12 PF08433.10 ORY06577.1 - 0.02 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 ORY06577.1 - 0.022 14.4 0.1 0.078 12.6 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 ORY06577.1 - 0.024 13.6 0.0 0.057 12.4 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 ORY06577.1 - 0.027 14.5 0.0 0.057 13.5 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase CbiA PF01656.23 ORY06577.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 ORY06577.1 - 0.03 14.0 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.14 ORY06577.1 - 0.032 14.1 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 ORY06577.1 - 0.047 12.9 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 ORY06577.1 - 0.052 13.3 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY06577.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 ORY06577.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 ORY06577.1 - 0.098 12.0 0.0 0.55 9.6 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY06577.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 ORY06577.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 ORY06577.1 - 0.14 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ORY06577.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Phosphoesterase PF04185.14 ORY06578.1 - 1.1e-31 110.4 1.3 1.1e-30 107.1 0.1 2.2 1 1 1 2 2 2 2 Phosphoesterase family Abhydrolase_1 PF00561.20 ORY06579.1 - 1.4e-32 113.3 0.1 6.7e-32 111.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY06579.1 - 6e-21 76.1 0.0 7.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY06579.1 - 3.9e-15 55.8 0.0 2.4e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ORY06579.1 - 1.2e-08 34.8 0.0 2.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase PF07224.11 ORY06579.1 - 0.0024 16.9 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 ORY06579.1 - 0.0026 16.7 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 ORY06579.1 - 0.0062 16.2 0.0 0.025 14.2 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 ORY06579.1 - 0.0071 15.1 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 ORY06579.1 - 0.01 15.6 0.0 0.08 12.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1057 PF06342.12 ORY06579.1 - 0.051 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 ORY06579.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY06580.1 - 7.2e-36 124.1 0.3 1e-34 120.4 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY06580.1 - 5.2e-21 76.3 0.0 7e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY06580.1 - 4.3e-15 55.6 0.0 1.8e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ORY06580.1 - 5.7e-08 32.6 0.0 4.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 ORY06580.1 - 0.00081 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 ORY06580.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 ORY06580.1 - 0.0017 17.1 0.0 0.0038 16.0 0.0 1.5 2 0 0 2 2 2 1 Ndr family Chlorophyllase PF07224.11 ORY06580.1 - 0.0021 17.1 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase DUF4783 PF16022.5 ORY06580.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) Peptidase_S9 PF00326.21 ORY06580.1 - 0.08 12.4 0.0 0.39 10.2 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF1057 PF06342.12 ORY06580.1 - 0.094 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 ORY06580.1 - 0.1 12.3 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORY06580.1 - 0.19 11.5 0.0 0.55 10.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 ORY06580.1 - 0.2 11.5 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Pirin PF02678.16 ORY06581.1 - 1.2e-28 99.2 0.8 2.2e-28 98.4 0.8 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 ORY06581.1 - 1.5e-14 53.9 0.1 1.8e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 ORY06581.1 - 0.00018 21.1 1.6 0.00043 19.9 0.8 1.9 2 0 0 2 2 2 1 Cupin domain HMG_box_5 PF14887.6 ORY06581.1 - 0.16 12.0 0.2 0.96 9.5 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DTW PF03942.15 ORY06582.1 - 3.7e-31 108.4 0.0 5.4e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 DTW domain Stc1 PF12898.7 ORY06582.1 - 0.018 15.6 2.1 0.038 14.5 2.1 1.5 1 0 0 1 1 1 0 Stc1 domain Sec7 PF01369.20 ORY06583.1 - 1.1e-68 230.5 3.3 2.1e-68 229.6 0.7 2.5 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 ORY06583.1 - 7.3e-18 65.0 0.0 7.3e-18 65.0 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY06583.1 - 0.0026 17.6 0.2 18 5.2 0.0 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) Mcp5_PH PF12814.7 ORY06583.1 - 0.082 13.0 0.1 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Oxysterol_BP PF01237.18 ORY06584.1 - 7.9e-72 242.1 0.6 9e-70 235.4 0.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Gti1_Pac2 PF09729.9 ORY06585.1 - 9.1e-46 156.2 5.2 1.1e-39 136.4 0.5 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Fe-S_biosyn PF01521.20 ORY06586.1 - 3.7e-21 75.4 0.1 4.3e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DNA_pol_A_exo1 PF01612.20 ORY06587.1 - 2e-17 63.5 0.0 4.9e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease USP8_dimer PF08969.11 ORY06588.1 - 2.2e-10 40.7 0.0 5.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 ORY06588.1 - 1.9e-06 28.3 0.0 9e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 ORY06589.1 - 2.4e-73 246.8 0.0 3e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06589.1 - 6.7e-36 123.9 0.0 8.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY06589.1 - 3.6e-09 37.2 2.8 9.2e-09 35.9 2.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 ORY06589.1 - 2e-08 33.9 0.1 2.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY06589.1 - 0.0012 18.5 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY06589.1 - 0.024 13.6 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY06589.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 ORY06589.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY06589.1 - 0.16 11.8 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LAMTOR5 PF16672.5 ORY06590.1 - 1.6e-20 72.8 0.1 1.7e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 ORY06590.1 - 5.5e-06 26.1 0.1 6.1e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain PH PF00169.29 ORY06591.1 - 4.4e-05 24.0 0.1 0.002 18.6 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 ORY06591.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 PH domain DUF1624 PF07786.12 ORY06592.1 - 5.3e-09 36.0 1.1 5.3e-09 36.0 1.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 ORY06592.1 - 3.7e-08 33.2 4.4 3.7e-08 33.2 4.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) DUF2975 PF11188.8 ORY06592.1 - 0.23 11.3 6.6 0.11 12.4 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ribosom_S12_S23 PF00164.25 ORY06593.1 - 2.3e-38 130.3 1.2 3.2e-38 129.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ELO PF01151.18 ORY06594.1 - 1e-62 212.0 12.7 1.1e-62 211.8 12.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GIDE PF12483.8 ORY06595.1 - 0.0065 15.9 0.0 0.0079 15.6 0.0 1.1 1 0 0 1 1 1 1 E3 Ubiquitin ligase Nup192 PF11894.8 ORY06596.1 - 0 1085.7 29.3 0 1085.5 29.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Velvet PF11754.8 ORY06597.1 - 2e-52 178.6 0.3 2.4e-38 132.5 0.1 2.0 1 1 1 2 2 2 2 Velvet factor IF4E PF01652.18 ORY06598.1 - 1.9e-56 190.2 1.2 2.8e-56 189.7 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RACo_linker PF17650.1 ORY06598.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 RACo linker region Tk-SP_N-pro PF18237.1 ORY06598.1 - 0.16 12.1 0.2 18 5.5 0.0 3.0 2 1 1 3 3 3 0 Tk-SP N-propeptide domain Rad21_Rec8_N PF04825.13 ORY06599.1 - 2.3e-12 47.0 0.0 2.3e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein SQHop_cyclase_C PF13243.6 ORY06602.1 - 2.4e-58 197.7 0.2 1e-52 179.2 0.1 2.9 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY06602.1 - 2.5e-52 177.8 0.5 1.8e-45 155.3 0.0 4.4 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORY06602.1 - 7.9e-38 127.9 3.5 1.5e-10 40.6 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORY06602.1 - 4.2e-06 26.0 0.1 0.035 13.1 0.0 4.1 3 1 1 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 ORY06602.1 - 0.00058 19.3 2.2 0.78 9.0 0.0 4.2 3 1 2 5 5 5 2 Pectic acid lyase DUF1925 PF09094.11 ORY06602.1 - 0.13 12.6 0.0 39 4.7 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) SURF4 PF02077.15 ORY06605.1 - 4.1e-75 252.8 9.3 4.6e-75 252.7 9.3 1.0 1 0 0 1 1 1 1 SURF4 family SURF4 PF02077.15 ORY06606.1 - 4.6e-75 252.7 7.6 5.1e-75 252.5 7.6 1.0 1 0 0 1 1 1 1 SURF4 family VPS11_C PF12451.8 ORY06607.1 - 1e-17 64.0 0.4 2.7e-17 62.7 0.4 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 ORY06607.1 - 3.1e-17 62.8 10.0 4.2e-17 62.4 4.5 3.0 2 1 1 3 3 3 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 ORY06607.1 - 7.1e-08 32.3 7.9 1.8e-07 31.1 7.9 1.7 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 ORY06607.1 - 0.0023 17.8 5.8 0.0023 17.8 5.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps8 PF12816.7 ORY06607.1 - 0.0084 15.6 3.5 0.18 11.3 1.0 2.6 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_5 PF14634.6 ORY06607.1 - 0.014 15.3 5.7 0.036 14.0 5.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 ORY06607.1 - 0.015 15.6 5.8 0.046 14.1 5.8 1.9 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 ORY06607.1 - 0.039 14.2 3.2 0.1 12.9 3.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY06607.1 - 0.84 9.6 5.8 2.8 7.9 5.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY06607.1 - 1.2 9.2 6.4 2.9 8.0 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger NCA2 PF08637.10 ORY06608.1 - 3.1e-82 276.0 2.7 6e-82 275.1 2.7 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF1852 PF08908.11 ORY06608.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) COA2 PF17051.5 ORY06609.1 - 3.4e-09 36.6 0.2 3.9e-09 36.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Pcc1 PF09341.10 ORY06610.1 - 8.3e-24 83.5 0.9 9.3e-24 83.4 0.9 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 CS PF04969.16 ORY06611.1 - 0.00091 20.2 0.1 0.0019 19.2 0.1 1.5 1 0 0 1 1 1 1 CS domain Cyclin PF08613.11 ORY06612.1 - 5.6e-15 56.1 0.0 6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY06612.1 - 7.3e-09 35.4 0.0 9.5e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain HLH PF00010.26 ORY06613.1 - 1.2e-11 44.4 0.6 3e-11 43.1 0.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RcbX PF02341.15 ORY06613.1 - 0.024 14.9 0.3 0.024 14.9 0.3 1.6 2 0 0 2 2 2 0 RbcX protein OmpH PF03938.14 ORY06613.1 - 1.6 9.0 10.5 0.2 12.0 5.3 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_M16_C PF05193.21 ORY06614.1 - 3.5e-17 63.0 0.0 1e-10 41.9 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY06614.1 - 5.1e-10 39.5 0.1 2.6e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 ORY06614.1 - 0.0018 17.4 0.2 0.012 14.8 0.2 2.1 1 1 0 1 1 1 1 Peptidase M16C associated Uso1_p115_head PF04869.14 ORY06614.1 - 0.0086 15.2 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Osteopontin PF00865.18 ORY06614.1 - 0.075 12.5 8.3 0.15 11.5 8.3 1.4 1 0 0 1 1 1 0 Osteopontin Mpp10 PF04006.12 ORY06614.1 - 0.079 11.4 5.1 0.12 10.8 5.1 1.1 1 0 0 1 1 1 0 Mpp10 protein SUIM_assoc PF16619.5 ORY06615.1 - 0.02 14.9 8.4 0.044 13.8 8.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 ORY06615.1 - 0.21 11.2 8.5 0.29 10.7 8.5 1.2 1 0 0 1 1 1 0 Spt20 family STE PF02200.16 ORY06616.1 - 0.15 12.5 0.3 0.35 11.3 0.3 1.5 1 1 0 1 1 1 0 STE like transcription factor DUF2722 PF10846.8 ORY06617.1 - 0.012 14.6 3.1 0.01 14.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 ORY06617.1 - 0.19 11.3 11.7 0.21 11.2 11.7 1.1 1 0 0 1 1 1 0 Spt20 family M_domain PF12938.7 ORY06617.1 - 2.6 7.8 26.4 0.23 11.3 19.5 2.0 1 1 1 2 2 2 0 M domain of GW182 STE PF02200.16 ORY06619.1 - 0.079 13.4 0.4 0.19 12.2 0.4 1.6 1 1 0 1 1 1 0 STE like transcription factor RAI16-like PF10257.9 ORY06620.1 - 3.6e-67 226.8 1.8 6.6e-67 225.9 1.8 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein zf-C2H2 PF00096.26 ORY06621.1 - 3e-13 49.4 9.6 2.4e-07 30.9 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY06621.1 - 8.2e-12 45.0 18.2 6.7e-08 32.6 3.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY06621.1 - 2.3e-07 31.1 8.4 0.00057 20.5 1.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY06621.1 - 0.0009 19.5 4.7 0.34 11.2 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY06621.1 - 0.0095 16.6 0.6 0.096 13.3 0.1 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY06621.1 - 0.01 16.1 1.0 0.021 15.1 1.0 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 ORY06621.1 - 0.024 14.6 4.4 0.058 13.3 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 ORY06621.1 - 0.026 15.0 4.6 0.51 10.8 0.4 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 ORY06621.1 - 0.036 14.5 2.0 0.65 10.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2225 PF09986.9 ORY06621.1 - 0.066 12.9 1.4 0.081 12.6 1.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf_ZIC PF18366.1 ORY06621.1 - 0.069 13.3 1.2 1.7 8.8 0.0 2.1 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 ORY06621.1 - 0.12 12.4 11.2 0.25 11.4 0.8 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY06621.1 - 0.14 12.5 3.4 59 4.1 0.2 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 ORY06622.1 - 4.3e-12 45.9 16.3 1.2e-07 31.8 2.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY06622.1 - 2.5e-11 43.4 9.6 1.4e-05 25.3 1.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY06622.1 - 6.5e-07 29.7 7.2 0.00094 19.8 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY06622.1 - 0.00025 21.3 0.9 0.00062 20.0 0.6 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY06622.1 - 0.01 15.8 8.3 0.73 9.9 0.5 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger DUF5572 PF17733.1 ORY06622.1 - 0.067 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5572) zf-C2H2_jaz PF12171.8 ORY06622.1 - 0.074 13.4 3.1 0.9 9.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 ORY06622.1 - 0.081 12.6 2.8 0.12 12.0 1.4 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-met PF12874.7 ORY06622.1 - 0.42 11.1 0.2 0.42 11.1 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORY06623.1 - 1.1e-08 35.1 16.3 0.00016 21.9 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY06623.1 - 5.9e-08 32.8 22.5 5.9e-07 29.6 4.8 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY06623.1 - 3.9e-05 24.1 13.9 0.014 16.2 3.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY06623.1 - 0.051 13.6 8.2 0.3 11.1 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.9 ORY06623.1 - 0.084 12.6 3.2 0.058 13.1 1.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF629 PF04780.12 ORY06623.1 - 0.28 9.7 4.6 0.37 9.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_8 PF15909.5 ORY06623.1 - 0.35 11.2 6.7 0.47 10.8 3.5 2.6 1 1 1 3 3 3 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 ORY06623.1 - 1.2 9.4 5.7 4.5 7.7 5.7 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 ORY06623.1 - 4.1 7.4 8.6 14 5.7 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Aldo_ket_red PF00248.21 ORY06624.1 - 1.1e-21 77.4 0.0 1e-20 74.2 0.0 2.4 1 1 0 1 1 1 1 Aldo/keto reductase family Xpo1 PF08389.12 ORY06624.1 - 0.023 14.7 0.3 0.057 13.5 0.1 1.7 2 0 0 2 2 2 0 Exportin 1-like protein Nucleo_P87 PF07267.11 ORY06624.1 - 0.028 13.3 0.1 0.04 12.8 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Casc1_N PF15927.5 ORY06624.1 - 0.066 12.9 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MIP PF00230.20 ORY06625.1 - 3.3e-48 164.4 11.7 4.1e-48 164.1 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein CPP1-like PF11833.8 ORY06625.1 - 4.3 7.0 7.1 13 5.4 0.1 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fzo_mitofusin PF04799.13 ORY06626.1 - 0.023 14.3 0.9 0.023 14.3 0.9 2.5 2 0 0 2 2 2 0 fzo-like conserved region Helo_like_N PF17111.5 ORY06626.1 - 0.058 12.8 0.2 0.058 12.8 0.2 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 ORY06626.1 - 0.064 13.3 0.5 0.064 13.3 0.5 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF685 PF05085.12 ORY06626.1 - 0.066 12.5 0.4 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF685) AAA_23 PF13476.6 ORY06626.1 - 1.5 9.3 10.8 0.54 10.7 7.1 1.8 2 0 0 2 2 2 0 AAA domain tRNA_int_endo PF01974.17 ORY06628.1 - 9.2e-23 80.1 0.4 1.7e-22 79.3 0.3 1.5 1 1 1 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 ORY06628.1 - 0.0004 20.0 0.1 0.00066 19.3 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DUF4646 PF15496.6 ORY06629.1 - 0.002 18.7 0.7 0.014 16.0 0.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) His_Phos_1 PF00300.22 ORY06630.1 - 4.1e-23 82.1 0.0 5e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_36 PF06165.11 ORY06631.1 - 0.058 12.8 0.1 0.1 12.0 0.1 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 36 RTC PF01137.21 ORY06632.1 - 3.9e-58 196.3 0.0 4.5e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ORY06632.1 - 1.2e-39 135.0 0.0 1.9e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain UL2 PF08196.11 ORY06633.1 - 0.067 13.2 0.8 0.067 13.2 0.8 2.2 2 0 0 2 2 2 0 UL2 protein Ldh_1_N PF00056.23 ORY06687.1 - 2.9e-36 124.7 1.5 5e-36 123.9 1.5 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORY06687.1 - 1.8e-21 76.8 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORY06687.1 - 0.0003 20.5 1.7 0.0018 17.9 0.8 2.4 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORY06687.1 - 0.008 16.7 0.7 0.035 14.7 0.3 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORY06687.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY06687.1 - 0.029 14.3 1.3 0.047 13.6 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY06687.1 - 0.042 14.1 0.2 0.073 13.3 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ORY06687.1 - 0.076 12.6 1.1 0.19 11.2 1.0 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 ORY06687.1 - 3.4 7.2 4.8 28 4.1 3.3 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lipase_3 PF01764.25 ORY06688.1 - 5.8e-25 87.8 0.0 9.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY06688.1 - 0.00044 20.9 0.0 0.00059 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY06688.1 - 0.016 14.8 0.6 0.12 12.0 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) ox_reductase_C PF08635.10 ORY06688.1 - 0.042 13.5 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Lipase_3 PF01764.25 ORY06689.1 - 5.8e-25 87.8 0.0 9.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY06689.1 - 0.00045 20.9 0.0 0.00059 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY06689.1 - 0.016 14.8 0.6 0.12 12.0 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) ox_reductase_C PF08635.10 ORY06689.1 - 0.037 13.7 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Lipase_3 PF01764.25 ORY06690.1 - 9.3e-36 122.8 0.0 1.2e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORY06690.1 - 0.00018 21.1 1.1 0.0014 18.3 1.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORY06690.1 - 0.0047 17.5 0.0 0.0052 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3472 PF11958.8 ORY06691.1 - 1.4e-14 54.9 0.7 2.1e-14 54.4 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 ORY06691.1 - 0.0013 18.7 0.2 0.0021 18.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) PRiA4_ORF3 PF07929.11 ORY06691.1 - 0.1 12.3 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein CBM_19 PF03427.13 ORY06692.1 - 0.018 15.0 13.9 0.074 13.1 3.6 3.0 2 1 0 2 2 2 0 Carbohydrate binding domain (family 19) CBM_14 PF01607.24 ORY06692.1 - 0.18 12.0 13.5 0.59 10.3 1.6 3.6 2 2 0 3 3 3 0 Chitin binding Peritrophin-A domain Defensin_beta_2 PF13841.6 ORY06692.1 - 5.9 7.5 6.6 22 5.7 0.5 3.1 3 0 0 3 3 3 0 Beta defensin Forkhead PF00250.18 ORY06693.1 - 6.1e-35 119.4 0.0 1e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain A_deamin PF02137.18 ORY06694.1 - 2.5e-75 254.0 0.0 2.9e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain ubiquitin PF00240.23 ORY06695.1 - 1.3e-21 76.1 0.2 2.8e-21 75.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY06695.1 - 3.8e-08 33.1 0.2 6.7e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORY06695.1 - 2.6e-05 24.3 0.1 0.00013 22.0 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4335 PF14233.6 ORY06695.1 - 0.01 15.7 2.0 0.22 11.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) DUF2407 PF10302.9 ORY06695.1 - 0.039 14.5 0.0 0.18 12.3 0.0 2.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY06695.1 - 0.21 11.7 0.2 2.2 8.4 0.2 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain DNA_primase_lrg PF04104.14 ORY06696.1 - 2.7e-89 299.1 1.9 3.6e-89 298.7 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Hpr_kinase_N PF02603.16 ORY06696.1 - 0.025 14.6 0.1 0.054 13.5 0.1 1.6 1 1 0 1 1 1 0 HPr Serine kinase N terminus Mur_ligase_C PF02875.21 ORY06696.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Ank_5 PF13857.6 ORY06697.1 - 7.7e-05 22.9 0.1 0.00016 21.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY06697.1 - 9e-05 23.0 0.7 0.021 15.4 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY06697.1 - 0.00071 19.8 0.6 0.29 11.8 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY06697.1 - 0.00076 20.0 1.0 0.0027 18.2 0.8 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY06697.1 - 0.0062 16.9 1.2 0.011 16.2 0.2 1.9 2 0 0 2 2 2 1 Ankyrin repeat FYVE PF01363.21 ORY06698.1 - 9.3e-18 64.1 13.4 1.4e-17 63.6 13.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 ORY06698.1 - 0.04 14.1 8.4 0.067 13.4 8.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-ribbon_3 PF13248.6 ORY06698.1 - 0.46 10.0 0.1 0.46 10.0 0.1 3.2 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 ORY06698.1 - 0.66 10.1 13.4 0.21 11.6 2.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon Fer4_21 PF14697.6 ORY06698.1 - 5.6 7.2 8.3 4 7.7 6.2 1.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Ribosomal_L11_N PF03946.14 ORY06699.1 - 1.5e-24 85.6 0.1 2.6e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY06699.1 - 3.1e-17 62.8 0.2 6.5e-17 61.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain MitMem_reg PF13012.6 ORY06700.1 - 7.3e-39 132.7 1.2 1.3e-38 131.9 1.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY06700.1 - 2.2e-31 108.3 0.0 4.7e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_L14 PF00238.19 ORY06701.1 - 3.1e-24 85.4 0.1 3.5e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ATP-synt_Eps PF04627.13 ORY06702.1 - 3.8e-22 78.0 3.3 4.7e-22 77.7 3.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain LSM PF01423.22 ORY06703.1 - 2.3e-18 65.7 0.2 3e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Propep_M14 PF02244.16 ORY06703.1 - 0.075 13.4 0.1 0.097 13.1 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Hfq PF17209.3 ORY06703.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein zf-CHCC PF10276.9 ORY06704.1 - 1.9e-17 63.0 2.5 2.6e-17 62.6 2.5 1.2 1 0 0 1 1 1 1 Zinc-finger domain Eapp_C PF10238.9 ORY06705.1 - 1.6e-40 138.6 1.3 1.9e-27 96.2 0.1 2.6 2 1 1 3 3 3 2 E2F-associated phosphoprotein TAF6_C PF07571.13 ORY06706.1 - 6.6e-33 112.9 0.0 1.9e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 ORY06706.1 - 1.2e-27 95.9 1.4 1.9e-27 95.2 0.3 2.0 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) HEAT_EZ PF13513.6 ORY06706.1 - 0.0015 19.0 0.0 0.18 12.4 0.0 3.3 3 1 1 4 4 4 1 HEAT-like repeat Histone PF00125.24 ORY06706.1 - 0.0021 18.4 0.5 0.0087 16.4 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORY06706.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HEAT PF02985.22 ORY06706.1 - 0.068 13.5 0.1 0.31 11.4 0.1 2.2 1 1 0 1 1 1 0 HEAT repeat DUF4777 PF16007.5 ORY06706.1 - 0.14 12.4 0.1 4 7.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) CBFD_NFYB_HMF PF00808.23 ORY06706.1 - 0.17 12.2 0.2 0.56 10.5 0.2 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SpoVIF PF14069.6 ORY06706.1 - 0.21 11.4 1.1 15 5.5 0.0 3.8 3 1 1 4 4 4 0 Stage VI sporulation protein F zf-RING_2 PF13639.6 ORY06707.1 - 2.2e-11 43.9 7.3 2.7e-11 43.6 5.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY06707.1 - 7.2e-09 35.8 7.1 2.2e-08 34.2 6.0 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY06707.1 - 8.6e-09 35.1 5.5 1.8e-08 34.1 4.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY06707.1 - 2.7e-08 33.7 3.3 1e-07 31.8 3.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY06707.1 - 4.2e-08 32.9 7.7 1.1e-07 31.5 5.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY06707.1 - 1.2e-06 28.3 2.0 1.2e-06 28.3 2.0 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY06707.1 - 1.5e-06 27.8 4.5 1.8e-05 24.4 1.8 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY06707.1 - 8.1e-06 25.8 0.7 1.9e-05 24.6 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY06707.1 - 1.9e-05 24.4 5.1 2.2e-05 24.2 3.3 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY06707.1 - 6.6e-05 22.8 4.9 7.6e-05 22.6 3.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 ORY06707.1 - 0.00031 20.3 2.5 0.00086 18.9 2.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 ORY06707.1 - 0.012 15.3 2.5 0.046 13.5 2.5 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Uds1 PF15456.6 ORY06707.1 - 0.084 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation zf-C3HC4_4 PF15227.6 ORY06707.1 - 0.3 11.3 7.3 0.16 12.2 4.7 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 ORY06707.1 - 0.6 10.3 4.5 1.3 9.2 4.5 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 ORY06707.1 - 0.95 9.7 6.4 5.6 7.2 6.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PEARLI-4 PF05278.12 ORY06708.1 - 0.018 14.6 0.8 0.022 14.3 0.8 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Gp-FAR-1 PF05823.12 ORY06708.1 - 0.02 15.2 1.9 0.026 14.9 1.9 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CHAD PF05235.14 ORY06708.1 - 0.083 12.8 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 CHAD domain AAA_13 PF13166.6 ORY06708.1 - 0.091 11.4 4.1 0.11 11.2 4.1 1.0 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 ORY06708.1 - 0.17 12.1 8.5 0.22 11.7 1.5 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Trns_repr_metal PF02583.17 ORY06708.1 - 0.27 11.6 2.1 0.36 11.2 0.2 2.1 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor SNF2_N PF00176.23 ORY06709.1 - 6.3e-61 206.0 1.2 2.5e-60 204.1 1.2 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY06709.1 - 9.8e-17 61.3 0.1 1.8e-15 57.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 ORY06709.1 - 9e-10 38.4 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_5 PF14634.6 ORY06709.1 - 3.1e-06 27.0 10.7 1.1e-05 25.3 10.7 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY06709.1 - 0.00028 20.7 10.1 0.0008 19.2 10.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MH2 PF03166.14 ORY06709.1 - 0.00067 19.9 0.7 0.055 13.7 0.1 2.5 2 0 0 2 2 2 1 MH2 domain zf-C3HC4_3 PF13920.6 ORY06709.1 - 0.0014 18.5 5.9 0.0014 18.5 5.9 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY06709.1 - 0.0016 18.7 8.6 0.0054 17.1 8.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY06709.1 - 0.016 15.1 10.2 0.052 13.4 10.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abi_2 PF07751.11 ORY06709.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Abi-like protein zf-RING_UBOX PF13445.6 ORY06709.1 - 0.098 12.7 7.8 0.23 11.5 7.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY06709.1 - 0.9 9.7 10.0 2.4 8.4 10.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY06709.1 - 1.6 8.6 9.2 0.71 9.8 6.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 ORY06709.1 - 5.6 7.1 7.8 19 5.4 7.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon POT1PC PF16686.5 ORY06711.1 - 4.2e-21 75.4 0.0 1.2e-19 70.7 0.1 2.8 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ORY06711.1 - 7.1e-14 51.9 0.6 1.9e-13 50.5 0.2 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Rep_fac-A_C PF08646.10 ORY06711.1 - 0.0047 16.7 0.0 0.016 14.9 0.0 1.8 1 1 1 2 2 2 1 Replication factor-A C terminal domain C1_1 PF00130.22 ORY06711.1 - 0.075 12.9 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNR_Alpha PF17975.1 ORY06712.1 - 8.7e-41 138.5 1.1 1.8e-40 137.5 0.2 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 ORY06712.1 - 1.5e-09 37.0 0.0 0.00021 20.0 0.0 3.4 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Cpn60_TCP1 PF00118.24 ORY06713.1 - 2.8e-86 290.1 9.2 4.1e-86 289.6 9.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ENTH PF01417.20 ORY06714.1 - 4.2e-51 172.2 0.0 6.1e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ORY06714.1 - 1e-06 28.0 0.0 2.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 ANTH domain UIM PF02809.20 ORY06714.1 - 6.6e-06 25.7 5.2 0.00085 19.1 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif VHS PF00790.19 ORY06714.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain PB1 PF00564.24 ORY06714.1 - 0.086 12.8 2.0 3.5 7.6 0.1 3.3 3 1 1 4 4 4 0 PB1 domain HSCB_C PF07743.13 ORY06715.1 - 7.1e-18 64.9 7.2 7.1e-18 64.9 7.2 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ORY06715.1 - 2.8e-06 27.3 0.9 1.2e-05 25.4 0.9 2.1 1 1 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.6 ORY06715.1 - 0.2 11.1 0.8 0.55 9.7 0.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain EF-hand_7 PF13499.6 ORY06716.1 - 1.2e-11 44.9 3.4 1.9e-11 44.2 3.4 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY06716.1 - 2.9e-08 33.0 2.4 0.0003 20.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORY06716.1 - 1.3e-06 28.1 5.3 0.012 15.4 0.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY06716.1 - 2.1e-06 26.9 3.0 7.5e-05 22.0 0.2 2.5 2 0 0 2 2 2 1 EF hand EF_assoc_2 PF08356.12 ORY06716.1 - 1.2e-05 25.2 0.2 2.5e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 EF hand associated EF-hand_5 PF13202.6 ORY06716.1 - 1.9e-05 24.0 3.6 0.0019 17.6 0.6 2.5 2 0 0 2 2 2 2 EF hand EF_assoc_1 PF08355.12 ORY06716.1 - 0.00017 21.1 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 EF hand associated DUF3976 PF13121.6 ORY06716.1 - 0.005 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3976) SPARC_Ca_bdg PF10591.9 ORY06716.1 - 0.047 14.0 0.7 0.09 13.1 0.5 1.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HEAT_EZ PF13513.6 ORY06717.1 - 2.1e-35 120.7 13.4 1.6e-11 44.4 0.0 11.4 11 2 3 14 14 12 7 HEAT-like repeat HEAT PF02985.22 ORY06717.1 - 9.2e-25 84.6 13.8 0.00013 21.9 0.0 10.9 12 0 0 12 12 11 5 HEAT repeat HEAT_2 PF13646.6 ORY06717.1 - 2.3e-18 66.3 0.0 0.0049 17.2 0.0 7.2 5 3 4 9 9 8 7 HEAT repeats Cnd1 PF12717.7 ORY06717.1 - 5.2e-13 49.4 0.0 0.011 15.8 0.0 4.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY06717.1 - 9.6e-11 42.1 0.0 0.024 15.2 0.0 6.0 5 3 3 8 8 8 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 ORY06717.1 - 4.4e-10 39.2 5.1 0.0039 17.2 0.0 6.7 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 ORY06717.1 - 6.7e-10 38.8 0.2 4.7e-09 36.0 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 ORY06717.1 - 3.1e-09 36.5 2.0 0.0076 15.4 0.0 4.1 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 ORY06717.1 - 1.9e-07 30.0 0.0 0.37 9.3 0.0 5.2 5 1 1 6 6 6 2 Adaptin N terminal region CAS_CSE1 PF03378.15 ORY06717.1 - 0.00061 18.4 0.1 0.009 14.5 0.0 2.8 4 0 0 4 4 4 1 CAS/CSE protein, C-terminus RTP1_C1 PF10363.9 ORY06717.1 - 0.0022 18.2 0.0 0.24 11.6 0.0 3.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 ORY06717.1 - 0.0026 17.3 0.2 11 5.5 0.0 4.7 3 2 3 6 6 6 0 Tti2 family DUF3437 PF11919.8 ORY06717.1 - 0.0044 16.9 0.0 13 5.7 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Ecm29 PF13001.7 ORY06717.1 - 0.012 14.4 0.2 1.9 7.1 0.0 3.3 2 2 2 4 4 4 0 Proteasome stabiliser TIP120 PF08623.10 ORY06717.1 - 0.06 13.1 0.0 12 5.6 0.0 3.8 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 ORY06717.1 - 0.13 12.6 0.2 52 4.3 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion CENP-T_N PF16171.5 ORY06717.1 - 0.25 10.2 0.1 0.42 9.5 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Lectin_leg-like PF03388.13 ORY06718.1 - 1.1e-61 208.2 0.1 1.5e-61 207.7 0.1 1.3 1 1 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ORY06718.1 - 0.00044 19.9 0.4 0.29 10.6 0.1 2.2 2 0 0 2 2 2 2 Legume lectin domain AA_kinase PF00696.28 ORY06719.1 - 2.2e-37 129.0 0.7 3.4e-37 128.3 0.7 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY06719.1 - 2.2e-14 53.1 0.1 2.2e-14 53.1 0.1 2.3 3 0 0 3 3 3 1 PUA domain CLASP_N PF12348.8 ORY06720.1 - 3.5e-29 102.0 14.1 2.8e-11 43.4 0.1 6.2 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.22 ORY06720.1 - 1.7e-17 62.0 8.6 0.00048 20.2 0.1 10.1 10 0 0 10 10 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY06720.1 - 8e-11 42.4 3.1 0.18 12.4 0.0 7.6 8 1 1 9 9 7 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 ORY06720.1 - 5.4e-10 39.5 3.6 0.38 11.2 0.0 7.1 7 1 0 7 7 6 2 HEAT repeats Cnd1 PF12717.7 ORY06720.1 - 7e-08 32.7 16.6 0.067 13.2 1.2 8.2 7 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY06720.1 - 1.2e-07 32.0 4.2 0.29 11.7 0.0 6.4 5 1 1 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 ORY06720.1 - 4.2e-05 23.7 11.2 0.33 11.2 0.0 6.0 8 0 0 8 8 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 ORY06720.1 - 0.0014 17.2 0.4 0.0014 17.2 0.4 3.3 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Tti2 PF10521.9 ORY06720.1 - 0.0015 18.1 0.7 0.034 13.7 0.0 3.6 4 0 0 4 4 4 1 Tti2 family IFRD PF05004.13 ORY06720.1 - 0.011 14.9 8.5 1.4 8.0 0.1 4.7 5 2 0 5 5 5 0 Interferon-related developmental regulator (IFRD) TAN PF11640.8 ORY06720.1 - 0.029 14.5 9.7 2.4 8.3 0.0 6.5 6 2 0 7 7 7 0 Telomere-length maintenance and DNA damage repair V-ATPase_H_C PF11698.8 ORY06720.1 - 0.032 14.3 1.4 8 6.6 0.0 4.5 4 0 0 4 4 4 0 V-ATPase subunit H T6SS_VasE PF05936.12 ORY06720.1 - 0.038 12.7 0.3 0.073 11.8 0.3 1.4 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DUF4800 PF16057.5 ORY06720.1 - 0.067 12.4 1.3 4.3 6.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Nipped-B_C PF12830.7 ORY06720.1 - 0.069 13.1 2.0 70 3.3 0.0 4.3 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 ORY06720.1 - 0.095 13.0 16.0 1.9 8.8 0.3 5.4 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 ORY06720.1 - 0.15 11.9 0.5 35 4.2 0.0 3.7 3 0 0 3 3 3 0 VHS domain RasGEF_N_2 PF14663.6 ORY06720.1 - 0.93 9.9 4.4 36 4.8 0.0 5.2 5 1 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SIKE PF05769.11 ORY06721.1 - 2.2e-12 47.3 25.5 4.3e-11 43.1 25.2 2.1 1 1 0 1 1 1 1 SIKE family GOLGA2L5 PF15070.6 ORY06721.1 - 0.0063 15.2 24.5 0.0091 14.7 7.9 2.0 1 1 1 2 2 2 2 Putative golgin subfamily A member 2-like protein 5 HALZ PF02183.18 ORY06721.1 - 0.033 14.4 20.5 1.5 9.1 6.5 4.3 3 2 0 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 ORY06721.1 - 0.13 12.9 27.8 0.35 11.5 7.3 3.6 1 1 2 3 3 3 0 Initiation control protein YabA Macoilin PF09726.9 ORY06721.1 - 0.18 10.3 12.0 0.19 10.3 12.0 1.1 1 0 0 1 1 1 0 Macoilin family SHE3 PF17078.5 ORY06721.1 - 0.39 10.4 22.7 1.2 8.8 7.7 3.2 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 PRKG1_interact PF15898.5 ORY06721.1 - 1.7 9.6 22.5 2.4 9.1 4.1 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_1 PF00170.21 ORY06721.1 - 4.2 7.5 27.1 0.64 10.2 8.0 4.6 3 1 2 5 5 5 0 bZIP transcription factor TMPIT PF07851.13 ORY06721.1 - 4.8 6.3 17.8 1.2 8.3 5.9 2.2 1 1 1 2 2 2 0 TMPIT-like protein AAA_lid_9 PF17871.1 ORY06721.1 - 5.7 6.9 11.1 4.6 7.2 0.8 2.9 2 2 1 3 3 3 0 AAA lid domain Exonuc_VII_L PF02601.15 ORY06721.1 - 8.8 5.8 12.6 12 5.3 12.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ofd1_CTDD PF10637.9 ORY06722.1 - 9.7e-81 270.9 0.0 1.6e-74 250.5 0.0 2.7 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY06722.1 - 2.8e-32 111.2 0.0 5.4e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY06722.1 - 6.9e-17 62.1 0.0 1.2e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dioxygenase_C PF00775.21 ORY06722.1 - 0.051 13.0 0.0 3.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Dioxygenase CAP18_C PF12153.8 ORY06722.1 - 0.12 12.3 0.5 4 7.4 0.1 2.3 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) ATP-synt_DE_N PF02823.16 ORY06723.1 - 1.8e-16 59.8 0.1 2.5e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATG_C PF09333.11 ORY06723.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain UQ_con PF00179.26 ORY06724.1 - 1.2e-18 67.1 0.0 3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1180 PF06679.12 ORY06724.1 - 0.071 13.5 4.0 0.12 12.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pro_isomerase PF00160.21 ORY06725.1 - 1e-49 168.8 0.2 1.2e-49 168.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Abhydrolase_6 PF12697.7 ORY06726.1 - 6.7e-13 49.7 0.0 8.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY06726.1 - 4.9e-11 42.4 0.0 1.9e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY06726.1 - 2.8e-06 27.2 0.0 0.00014 21.6 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY06726.1 - 0.00078 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY06726.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sugar_tr PF00083.24 ORY06727.1 - 9.3e-129 430.2 19.4 1.1e-128 429.9 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY06727.1 - 8e-30 103.9 34.0 8.6e-23 80.8 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY06727.1 - 2.3e-06 26.4 13.7 0.00067 18.3 0.0 3.6 4 0 0 4 4 4 2 MFS/sugar transport protein DUF441 PF04284.13 ORY06727.1 - 0.00065 19.7 0.2 0.00065 19.7 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF441) DUF2232 PF09991.9 ORY06727.1 - 0.0066 15.7 1.5 0.0066 15.7 1.5 3.3 4 0 0 4 4 4 1 Predicted membrane protein (DUF2232) OATP PF03137.20 ORY06727.1 - 0.0073 14.6 7.1 0.087 11.1 0.4 2.7 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family O-FucT PF10250.9 ORY06728.1 - 1.3e-12 48.1 0.6 1.1e-11 45.1 0.6 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF2434 PF10361.9 ORY06728.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) PGF-CTERM PF18204.1 ORY06729.1 - 0.46 10.5 3.7 0.84 9.7 3.7 1.5 1 0 0 1 1 1 0 PGF-CTERM motif FAD_binding_6 PF00970.24 ORY06731.1 - 7.7e-35 119.2 0.0 1.2e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY06731.1 - 1.6e-33 115.6 0.0 2.5e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY06731.1 - 4e-09 36.8 0.1 3.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORY06731.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain CAP_GLY PF01302.25 ORY06732.1 - 7.5e-27 93.1 1.9 1.2e-26 92.5 1.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 ORY06732.1 - 4.8e-24 84.6 0.0 8.7e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 ORY06732.1 - 5.3e-05 22.9 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Arcadin_1 PF18653.1 ORY06732.1 - 0.12 12.5 0.2 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Arcadin 1 PRELI PF04707.14 ORY06733.1 - 6.4e-47 159.3 0.0 7.3e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family VRR_NUC PF08774.11 ORY06734.1 - 1e-25 89.9 0.0 2.2e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain CTP_transf_like PF01467.26 ORY06735.1 - 1.2e-10 41.7 0.1 2e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 ORY06735.1 - 0.075 12.9 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 FAD synthetase TFIIE_alpha PF02002.17 ORY06735.1 - 0.21 11.5 1.5 3.9 7.4 0.2 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit Csm2_III-A PF03750.13 ORY06735.1 - 0.39 11.6 2.9 5.7 7.8 0.1 3.0 2 1 1 3 3 3 0 Csm2 Type III-A zf-RING_4 PF14570.6 ORY06736.1 - 1.4e-22 79.2 12.0 3.8e-22 77.8 12.0 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY06736.1 - 8.3e-08 32.0 8.8 8.3e-08 32.0 8.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 ORY06736.1 - 4.2e-07 29.7 0.0 3.3e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 ORY06736.1 - 0.0002 21.3 4.9 0.00051 20.0 4.9 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 ORY06736.1 - 0.00082 19.2 13.1 0.0095 15.8 9.8 2.9 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Nup35_RRM_2 PF14605.6 ORY06736.1 - 0.0024 17.8 0.2 0.0073 16.3 0.1 1.9 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-RING_2 PF13639.6 ORY06736.1 - 0.0038 17.5 12.2 0.0038 17.5 12.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 ORY06736.1 - 0.012 15.7 3.7 0.023 14.8 3.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Rtf2 PF04641.12 ORY06736.1 - 0.029 13.8 2.1 0.042 13.2 2.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 ORY06736.1 - 0.045 13.6 12.7 0.14 12.1 12.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1154 PF06631.11 ORY06736.1 - 0.047 13.7 0.8 0.084 12.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) zf-C3HC4_2 PF13923.6 ORY06736.1 - 0.11 12.3 15.0 0.05 13.5 12.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY06736.1 - 5.4 7.1 13.7 0.26 11.3 7.1 2.3 2 1 1 3 3 3 0 RING-type zinc-finger Ras PF00071.22 ORY06737.1 - 3e-45 153.7 0.3 3.5e-45 153.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY06737.1 - 3.8e-15 56.1 0.2 6.7e-15 55.4 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY06737.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY06737.1 - 9.8e-06 25.2 0.1 5.5e-05 22.8 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY06737.1 - 0.00067 19.1 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY06737.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY06737.1 - 0.0074 16.2 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 ORY06737.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DoxA PF07680.11 ORY06737.1 - 0.11 12.4 0.2 0.27 11.1 0.1 1.7 1 1 0 1 1 1 0 TQO small subunit DoxA Trypsin PF00089.26 ORY06738.1 - 3e-18 66.5 0.0 3.2e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Usp PF00582.26 ORY06739.1 - 1.4e-23 83.9 0.1 2.2e-22 80.1 0.1 2.0 1 1 0 1 1 1 1 Universal stress protein family Ntox1 PF15500.6 ORY06739.1 - 0.13 12.7 1.6 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 SOG2 PF10428.9 ORY06740.1 - 6.8e-25 88.2 9.1 5.4e-12 45.7 0.1 2.3 1 1 1 2 2 2 2 RAM signalling pathway protein LRR_8 PF13855.6 ORY06740.1 - 1.5e-16 59.9 25.7 9.8e-07 28.5 0.1 4.5 4 1 3 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 ORY06740.1 - 1.5e-10 41.1 17.3 0.00024 21.4 0.0 5.9 4 1 4 8 8 8 5 Leucine Rich repeats (2 copies) DUF4093 PF13331.6 ORY06740.1 - 0.026 15.0 0.8 0.18 12.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) LRR_6 PF13516.6 ORY06740.1 - 0.36 11.0 2.6 16 5.9 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 ORY06740.1 - 5.9 7.9 22.0 8.3 7.4 0.2 7.7 9 0 0 9 9 9 0 Leucine Rich Repeat NAPRTase_N PF17767.1 ORY06741.1 - 0.069 13.5 0.7 0.086 13.2 0.7 1.1 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain AAR2 PF05282.11 ORY06742.1 - 4.3e-65 220.4 0.6 1.4e-50 172.7 0.1 3.0 1 1 1 2 2 2 2 AAR2 protein Glyco_transf_49 PF13896.6 ORY06743.1 - 9.1e-61 206.0 2.3 2.3e-47 162.0 0.8 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 ORY06743.1 - 0.00086 19.8 0.3 0.0023 18.4 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 ArAE_2 PF10334.9 ORY06744.1 - 3e-12 46.9 2.8 4e-11 43.2 2.8 2.0 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 adh_short PF00106.25 ORY06792.1 - 6.9e-18 64.8 0.1 7.3e-18 64.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY06792.1 - 5e-12 45.9 0.1 5.3e-12 45.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY06792.1 - 1.8e-09 37.8 0.0 1.8e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY06792.1 - 5.7e-08 32.9 0.1 6.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY06792.1 - 0.00072 19.2 0.0 0.00081 19.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY06792.1 - 0.0026 17.2 0.0 0.003 17.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY06792.1 - 0.009 15.0 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY06792.1 - 0.019 14.0 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Bacteroid_pep PF14406.6 ORY06792.1 - 0.041 14.2 0.1 0.072 13.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes DUF2120 PF09893.9 ORY06792.1 - 0.042 14.0 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Polysacc_synt_2 PF02719.15 ORY06792.1 - 0.069 12.3 0.0 0.076 12.1 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LCAT PF02450.15 ORY06793.1 - 8.8e-97 324.7 0.0 2.7e-96 323.1 0.0 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 ORY06793.1 - 0.0001 21.9 0.0 0.00038 20.0 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 2) DUF676 PF05057.14 ORY06793.1 - 0.00051 19.6 0.0 0.01 15.4 0.1 2.3 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY06793.1 - 0.038 14.6 0.0 0.59 10.7 0.0 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.11 ORY06793.1 - 0.052 12.9 1.3 0.15 11.4 0.2 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) ACT_7 PF13840.6 ORY06794.1 - 4.1e-12 45.7 0.0 7.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 ACT domain Castor1_N PF18700.1 ORY06794.1 - 0.00029 20.6 0.1 0.0007 19.4 0.0 1.7 2 0 0 2 2 2 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain AphA_like PF14557.6 ORY06794.1 - 0.2 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Med4 PF10018.9 ORY06795.1 - 2.9e-20 72.8 5.6 3.9e-20 72.4 5.6 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HBM PF16591.5 ORY06795.1 - 0.00081 18.9 2.6 0.00081 18.9 2.6 1.6 2 0 0 2 2 2 1 Helical bimodular sensor domain Med7 PF05983.11 ORY06795.1 - 0.0016 18.5 1.4 0.002 18.3 0.5 1.6 2 0 0 2 2 1 1 MED7 protein LMP PF04778.12 ORY06795.1 - 0.002 18.1 1.8 0.003 17.5 1.8 1.3 1 0 0 1 1 1 1 LMP repeated region Tropomyosin_1 PF12718.7 ORY06795.1 - 0.0038 17.4 5.6 0.0038 17.4 5.6 2.1 2 0 0 2 2 2 1 Tropomyosin like RasGAP_C PF03836.15 ORY06795.1 - 0.0079 16.3 3.0 0.015 15.4 3.0 1.4 1 0 0 1 1 1 1 RasGAP C-terminus CorA PF01544.18 ORY06795.1 - 0.009 15.4 4.2 0.012 15.0 4.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 ORY06795.1 - 0.011 15.2 8.0 0.016 14.7 8.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 ORY06795.1 - 0.011 16.0 4.2 0.02 15.1 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) LUC7 PF03194.15 ORY06795.1 - 0.015 15.0 1.4 0.016 14.9 1.4 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF3560 PF12083.8 ORY06795.1 - 0.015 15.4 1.4 0.03 14.4 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Gp58 PF07902.11 ORY06795.1 - 0.017 13.4 0.8 0.027 12.8 0.8 1.3 1 0 0 1 1 1 0 gp58-like protein V_ATPase_I PF01496.19 ORY06795.1 - 0.018 13.0 0.8 0.024 12.6 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 ORY06795.1 - 0.018 13.9 1.3 0.021 13.7 1.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-H PF05837.12 ORY06795.1 - 0.024 15.0 4.6 0.048 14.1 4.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FapA PF03961.13 ORY06795.1 - 0.028 13.0 3.9 0.035 12.7 3.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec8_exocyst PF04048.14 ORY06795.1 - 0.03 14.2 2.7 0.06 13.2 2.7 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 ORY06795.1 - 0.032 14.3 2.8 0.08 13.0 2.5 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Snapin_Pallidin PF14712.6 ORY06795.1 - 0.047 14.1 1.3 0.047 14.1 1.3 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DUF3450 PF11932.8 ORY06795.1 - 0.063 12.6 5.3 0.1 11.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1043 PF06295.12 ORY06795.1 - 0.081 12.9 4.6 0.028 14.4 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Seryl_tRNA_N PF02403.22 ORY06795.1 - 0.13 12.5 5.2 0.26 11.5 5.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 ORY06795.1 - 0.19 10.8 3.3 0.24 10.5 3.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 ORY06795.1 - 0.21 11.2 5.6 0.44 10.1 5.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Synaptobrevin PF00957.21 ORY06795.1 - 0.23 11.3 0.9 0.43 10.4 0.9 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF724 PF05266.14 ORY06795.1 - 0.28 11.0 6.4 0.5 10.2 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1003 PF06210.11 ORY06795.1 - 0.46 10.6 1.7 1 9.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) KapB PF08810.10 ORY06795.1 - 0.49 10.6 4.6 1.2 9.4 4.6 1.5 1 0 0 1 1 1 0 Kinase associated protein B Fib_alpha PF08702.10 ORY06795.1 - 0.7 10.1 5.0 1.2 9.3 5.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 ORY06795.1 - 1.5 8.0 5.4 2.2 7.5 5.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 ORY06795.1 - 6 7.6 9.0 1.9 9.1 3.3 2.7 2 1 1 3 3 2 0 SlyX LRR_8 PF13855.6 ORY06796.1 - 0.022 14.5 8.8 9.2 6.1 0.3 4.8 3 1 2 5 5 5 0 Leucine rich repeat DnaGprimase_HBD PF16730.5 ORY06796.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain LRR_1 PF00560.33 ORY06796.1 - 3.6 8.5 0.0 3.6 8.5 0.0 5.6 8 0 0 8 8 8 0 Leucine Rich Repeat zf-C3HC4_3 PF13920.6 ORY06797.1 - 3.9e-05 23.4 10.0 3.9e-05 23.4 10.0 3.7 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF1722 PF08349.11 ORY06797.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Bac_globin PF01152.21 ORY06798.1 - 2.4e-09 37.4 0.1 3.4e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ORY06798.1 - 0.0094 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Protoglobin DUF4918 PF16265.5 ORY06798.1 - 0.041 13.4 0.1 0.06 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) ETC_C1_NDUFA5 PF04716.14 ORY06799.1 - 1e-24 86.1 0.1 2e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region AIM5 PF17050.5 ORY06800.1 - 0.011 16.5 0.9 0.079 13.8 0.1 1.9 1 1 1 2 2 2 0 Altered inheritance of mitochondria 5 Rcd1 PF04078.13 ORY06802.1 - 1.5e-115 385.0 3.3 1.7e-115 384.8 3.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.25 ORY06804.1 - 5.1e-49 167.0 0.0 2.1e-48 165.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06804.1 - 1.1e-20 74.0 0.0 1.9e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY06804.1 - 0.00097 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY06804.1 - 0.0025 17.5 0.1 0.013 15.2 0.1 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 ORY06804.1 - 0.045 13.3 0.9 0.086 12.4 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 ORY06804.1 - 0.12 11.7 0.1 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mus7 PF09462.10 ORY06805.1 - 1.1e-60 206.3 5.5 2.5e-60 205.0 5.5 1.6 1 1 0 1 1 1 1 Mus7/MMS22 family MMS22L_C PF14911.6 ORY06805.1 - 0.029 13.5 0.9 0.29 10.2 0.9 2.1 1 1 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal MIF4G PF02854.19 ORY06806.1 - 4.2e-63 212.8 6.1 3.8e-33 114.9 0.0 4.3 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 ORY06806.1 - 2.3e-37 128.8 17.0 2.3e-37 128.8 17.0 3.4 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Complex1_LYR PF05347.15 ORY06807.1 - 1.5e-09 37.7 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY06807.1 - 2.1e-07 31.6 1.3 3e-07 31.1 1.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like ARID PF01388.21 ORY06809.1 - 1.1e-20 74.1 0.0 2.7e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 ORY06809.1 - 5.6e-05 23.7 0.2 0.00052 20.6 0.0 2.3 2 0 0 2 2 2 1 RFX DNA-binding domain BAF250_C PF12031.8 ORY06809.1 - 0.0018 17.6 1.3 0.0077 15.6 0.2 2.3 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa FOXP-CC PF16159.5 ORY06809.1 - 0.0023 18.5 4.6 0.0051 17.4 3.2 2.4 2 1 1 3 3 3 1 FOXP coiled-coil domain HeH PF12949.7 ORY06809.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain Sec7 PF01369.20 ORY06812.1 - 3e-50 170.4 0.0 3.9e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 ORY06812.1 - 0.02 14.9 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 PH domain Cys_Met_Meta_PP PF01053.20 ORY06813.1 - 8.9e-148 491.9 0.0 1e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORY06813.1 - 2.5e-11 43.5 0.2 4.5e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY06813.1 - 5.9e-11 41.9 0.1 9.8e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORY06813.1 - 4.6e-09 35.9 0.1 6.5e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY06813.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 ORY06813.1 - 0.0014 17.2 0.1 0.0019 16.8 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 ORY06813.1 - 0.0069 16.6 0.1 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 ORY06813.1 - 0.068 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CUE PF02845.16 ORY06814.1 - 1e-09 37.9 0.0 1.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain SCA7 PF08313.12 ORY06816.1 - 3.3e-28 97.4 0.2 3.3e-28 97.4 0.2 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 ORY06816.1 - 0.0019 17.7 0.2 0.0036 16.8 0.2 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) SMC_Nse1 PF07574.13 ORY06817.1 - 1.7e-25 90.1 0.4 7.4e-24 84.7 0.4 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 ORY06817.1 - 1.8e-11 44.2 6.2 2.6e-11 43.6 6.2 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 ORY06817.1 - 5.7e-06 26.6 6.4 8.8e-06 26.0 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY06817.1 - 0.00034 20.8 2.6 0.00063 20.0 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY06817.1 - 0.00054 20.0 2.4 0.00084 19.3 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 ORY06817.1 - 0.012 15.8 4.0 0.028 14.6 4.1 1.6 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY06817.1 - 0.02 15.0 0.9 0.032 14.4 0.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF2161 PF09929.9 ORY06817.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) zf-C3HC4_2 PF13923.6 ORY06817.1 - 0.63 9.9 6.1 1 9.2 6.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY06817.1 - 2.5 7.9 6.4 0.45 10.3 2.9 1.6 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 ORY06817.1 - 2.7 8.0 6.4 4.9 7.2 6.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HECT PF00632.25 ORY06818.1 - 5.7e-97 324.9 0.0 8.7e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORY06818.1 - 2.3e-35 120.4 19.1 1.1e-12 47.8 2.5 4.2 4 0 0 4 4 4 3 WW domain C2 PF00168.30 ORY06818.1 - 2.3e-19 69.6 0.1 5.5e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain PhyH PF05721.13 ORY06819.1 - 2.7e-12 47.4 0.0 3.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DNA_pol_E_B PF04042.16 ORY06820.1 - 2.1e-34 118.8 0.0 2.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORY06820.1 - 4.2e-16 59.2 0.0 6.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Not1 PF04054.15 ORY06821.1 - 7.5e-152 505.5 3.5 2.2e-150 500.7 0.6 3.0 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 ORY06821.1 - 2.1e-102 341.3 3.1 2.1e-102 341.3 3.1 3.0 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 ORY06821.1 - 2.4e-64 216.0 0.3 2.4e-64 216.0 0.3 3.0 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 ORY06821.1 - 4.1e-47 159.8 5.2 4.1e-47 159.8 5.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 ORY06821.1 - 2.3e-42 144.6 1.0 7.8e-42 142.9 0.4 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FANCI_S2 PF14676.6 ORY06821.1 - 0.65 10.3 2.7 32 4.8 0.0 4.4 6 0 0 6 6 6 0 FANCI solenoid 2 BRCT_2 PF16589.5 ORY06822.1 - 5.5e-13 49.1 0.1 5.7e-08 33.1 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY06822.1 - 9.6e-09 35.5 0.1 0.01 16.2 0.1 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain SWIRM-assoc_2 PF16496.5 ORY06822.1 - 0.0013 17.8 0.1 0.0013 17.8 0.1 2.7 2 1 0 2 2 2 1 SWIRM-associated domain at the N-terminal BRCT_3 PF18428.1 ORY06822.1 - 0.0032 17.5 0.0 0.083 13.0 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-RanBP PF00641.18 ORY06822.1 - 0.0061 15.8 6.1 0.0061 15.8 6.1 2.1 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others RTT107_BRCT_5 PF16770.5 ORY06822.1 - 0.015 15.2 0.0 0.079 12.8 0.0 2.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain MIR PF02815.19 ORY06823.1 - 3.9e-12 46.4 5.2 1.2e-08 35.0 2.4 2.9 1 1 1 2 2 2 2 MIR domain Mannosyl_trans PF05007.13 ORY06824.1 - 2.1e-78 263.8 18.2 2.1e-78 263.8 18.2 1.7 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 ORY06824.1 - 2.5e-11 43.3 19.3 3.1e-11 43.0 19.3 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 ORY06824.1 - 2.3e-06 27.5 3.4 2.3e-06 27.5 3.4 2.7 2 1 0 2 2 2 1 Glycosyltransferase family 87 Pkinase PF00069.25 ORY06825.1 - 6.8e-71 238.7 0.0 8.2e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06825.1 - 1.1e-47 162.5 0.0 1.4e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY06825.1 - 4.9e-06 25.6 0.0 7.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY06825.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY06825.1 - 0.0052 15.8 0.1 2 7.3 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Abi_2 PF07751.11 ORY06825.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Abi-like protein APH PF01636.23 ORY06825.1 - 0.12 12.2 0.0 1.5 8.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pex14_N PF04695.13 ORY06826.1 - 9.5e-19 68.6 1.3 1.2e-15 58.5 0.3 2.3 1 1 1 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region SCP2 PF02036.17 ORY06827.1 - 3.8e-27 94.7 1.6 4.2e-27 94.6 1.6 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORY06827.1 - 0.00013 22.2 0.3 0.00018 21.8 0.3 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 ORY06827.1 - 0.0014 19.0 0.0 0.0025 18.2 0.0 1.4 1 1 0 1 1 1 1 Sterol carrier protein domain SCP2 PF02036.17 ORY06828.1 - 1.6e-27 95.9 2.2 1.8e-27 95.7 2.2 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORY06828.1 - 0.00062 20.0 0.2 0.00077 19.7 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ribul_P_3_epim PF00834.19 ORY06829.1 - 4.7e-77 257.9 0.3 5.3e-77 257.7 0.3 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 ORY06829.1 - 0.00019 21.2 0.1 0.00052 19.8 0.0 1.7 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 ORY06829.1 - 0.012 15.1 0.1 0.069 12.6 0.1 2.1 1 1 2 3 3 3 0 Histidine biosynthesis protein OMPdecase PF00215.24 ORY06829.1 - 0.017 14.7 1.6 0.15 11.6 1.6 2.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PFOR_II PF17147.4 ORY06829.1 - 0.06 13.6 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II SporV_AA PF12164.8 ORY06829.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AA Alpha_L_fucos PF01120.17 ORY06829.1 - 0.2 11.1 0.0 0.76 9.2 0.0 1.7 1 1 0 2 2 2 0 Alpha-L-fucosidase Rad60-SLD_2 PF13881.6 ORY06830.1 - 2.3e-19 69.5 0.0 2.7e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY06830.1 - 2.3e-06 27.3 0.0 7.6e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 ORY06830.1 - 0.082 13.5 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain EF-hand_7 PF13499.6 ORY06831.1 - 2.1e-22 79.3 0.9 9.2e-13 48.5 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY06831.1 - 3.8e-16 57.3 4.1 5e-05 22.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY06831.1 - 1.6e-14 53.5 2.7 1.5e-08 34.3 0.1 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 ORY06831.1 - 1e-13 51.4 0.0 1.4e-05 25.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 ORY06831.1 - 3.2e-13 48.5 3.5 0.0023 17.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 ORY06831.1 - 0.00018 20.8 4.5 0.0082 15.6 0.2 3.4 4 0 0 4 4 4 2 EF hand Dockerin_1 PF00404.18 ORY06831.1 - 0.0033 17.6 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Dockerin type I domain DUF3008 PF11450.8 ORY06831.1 - 0.0047 17.0 2.2 0.014 15.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknwon function (DUF3008) EF-hand_4 PF12763.7 ORY06831.1 - 0.0075 16.2 0.1 0.99 9.4 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 ORY06831.1 - 0.0079 16.3 0.1 0.038 14.1 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Styelin PF17562.2 ORY06831.1 - 0.06 13.7 0.3 0.12 12.8 0.0 1.6 2 0 0 2 2 1 0 Styelin Syntaxin PF00804.25 ORY06832.1 - 3.6e-28 98.6 13.9 3.6e-28 98.6 13.9 1.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 ORY06832.1 - 5.6e-13 48.7 2.0 5.6e-13 48.7 2.0 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 ORY06832.1 - 0.00011 22.5 2.2 0.00011 22.5 2.2 2.5 2 1 1 3 3 3 1 Syntaxin-like protein Vps51 PF08700.11 ORY06832.1 - 0.0047 17.0 5.3 0.49 10.5 0.2 2.7 2 1 0 2 2 2 2 Vps51/Vps67 Tweety PF04906.13 ORY06832.1 - 0.0053 15.5 2.4 0.0053 15.5 2.4 2.1 2 1 0 2 2 2 1 Tweety SKA1 PF07160.12 ORY06832.1 - 0.007 16.2 8.1 0.018 14.9 2.3 2.2 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 Herpes_UL17 PF04559.12 ORY06832.1 - 0.045 12.6 2.9 0.047 12.5 2.1 1.3 1 1 0 1 1 1 0 Herpesvirus UL17 protein DUF4094 PF13334.6 ORY06832.1 - 0.056 13.9 4.3 0.17 12.3 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) BMFP PF04380.13 ORY06832.1 - 0.098 13.2 0.5 0.098 13.2 0.5 3.3 3 1 0 3 3 3 0 Membrane fusogenic activity RSS_P20 PF11757.8 ORY06832.1 - 0.12 12.9 9.6 0.31 11.5 0.4 2.9 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain VIT1 PF01988.19 ORY06832.1 - 0.14 12.0 2.4 0.34 10.8 2.4 1.9 1 1 0 1 1 1 0 VIT family DUF5383 PF17355.2 ORY06832.1 - 0.25 11.7 3.3 0.16 12.4 1.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) DUF4988 PF16378.5 ORY06832.1 - 0.99 9.0 8.9 0.78 9.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function Pex24p PF06398.11 ORY06832.1 - 1.1 8.2 6.2 4.6 6.1 5.9 2.1 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Med9 PF07544.13 ORY06832.1 - 1.8 8.7 7.1 3.8 7.7 0.4 3.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Orf78 PF06024.12 ORY06832.1 - 2 8.7 8.0 0.14 12.5 1.7 2.2 2 1 0 2 2 2 0 Orf78 (ac78) V-SNARE PF05008.15 ORY06832.1 - 3.2 8.2 8.1 0.83 10.1 1.0 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.10 ORY06832.1 - 5.2 7.3 15.7 1 9.5 2.9 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Itfg2 PF15907.5 ORY06833.1 - 8.8e-79 265.0 1.1 2.8e-51 174.5 0.3 3.1 2 1 1 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 ORY06833.1 - 8.3e-11 41.9 0.5 0.052 13.6 0.0 4.1 3 1 2 5 5 5 3 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 ORY06833.1 - 6.9e-05 23.4 10.3 0.71 10.5 0.0 4.7 4 1 1 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 ORY06833.1 - 0.018 13.8 0.0 0.29 9.9 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF4792 PF16040.5 ORY06833.1 - 0.049 13.5 2.4 0.11 12.4 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) Lsr2 PF11774.8 ORY06833.1 - 0.083 13.0 0.9 1.8 8.8 0.0 2.8 3 0 0 3 3 3 0 Lsr2 BBS1 PF14779.6 ORY06833.1 - 0.085 12.3 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 FG-GAP PF01839.23 ORY06833.1 - 0.19 11.9 15.5 0.29 11.3 0.2 3.9 4 0 0 4 4 4 0 FG-GAP repeat NT-C2 PF10358.9 ORY06833.1 - 0.43 10.3 3.9 3.6 7.3 0.7 2.4 1 1 1 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Asp PF00026.23 ORY06834.1 - 5.9e-59 200.0 0.0 6.5e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY06834.1 - 0.0063 16.3 0.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 ORY06834.1 - 0.02 15.1 0.1 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Topo_Zn_Ribbon PF08272.11 ORY06834.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Cpn60_TCP1 PF00118.24 ORY06836.1 - 9.6e-149 496.1 10.1 1.1e-148 495.9 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 ORY06836.1 - 0.04 14.1 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 ORY06836.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Amidase PF01425.21 ORY06837.1 - 1.4e-125 419.8 0.1 3e-125 418.7 0.1 1.5 1 1 0 1 1 1 1 Amidase EC042_2821 PF18740.1 ORY06837.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 EC042_2821-lke REase Cyclin_N PF00134.23 ORY06839.1 - 4.4e-47 159.0 0.1 6e-46 155.3 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY06839.1 - 4.3e-40 136.5 0.0 9e-40 135.5 0.0 1.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain DDE_1 PF03184.19 ORY06839.1 - 0.018 14.7 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease TIP49 PF06068.13 ORY06840.1 - 1.1e-168 561.0 2.0 1.5e-168 560.5 2.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY06840.1 - 5.9e-26 90.4 0.0 1.6e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY06840.1 - 7.3e-11 42.6 0.2 1.2e-06 29.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY06840.1 - 1.8e-09 37.6 0.1 3.7e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY06840.1 - 2.5e-05 24.6 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY06840.1 - 0.00017 22.1 0.0 0.002 18.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 ORY06840.1 - 0.00055 20.3 1.5 0.35 11.2 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY06840.1 - 0.00065 19.7 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY06840.1 - 0.0007 19.0 0.2 0.026 13.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORY06840.1 - 0.00078 19.2 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 ORY06840.1 - 0.0022 18.5 0.0 0.017 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORY06840.1 - 0.0051 16.4 0.0 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORY06840.1 - 0.0054 17.0 0.1 0.01 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY06840.1 - 0.0058 15.9 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.6 ORY06840.1 - 0.0073 16.3 0.0 0.88 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY06840.1 - 0.019 15.0 0.0 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY06840.1 - 0.033 13.2 0.8 0.14 11.2 0.1 2.2 2 1 0 3 3 3 0 Type II/IV secretion system protein AAA_7 PF12775.7 ORY06840.1 - 0.048 13.2 0.1 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 ORY06840.1 - 0.053 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 ORY06840.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1002 PF06207.11 ORY06840.1 - 0.095 12.2 1.7 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) DnaB_C PF03796.15 ORY06840.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain G10 PF01125.17 ORY06841.1 - 2.5e-65 218.7 5.6 2.8e-65 218.5 5.6 1.0 1 0 0 1 1 1 1 G10 protein Ribosomal_L2_C PF03947.18 ORY06842.1 - 1.3e-54 183.7 3.3 2.9e-54 182.6 3.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY06842.1 - 7.2e-25 86.8 0.2 1.4e-24 85.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SNAP PF14938.6 ORY06843.1 - 1.7e-113 378.8 22.5 1.9e-113 378.6 22.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 ORY06843.1 - 3.2e-08 33.7 11.5 6.6e-06 26.3 0.4 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat DHR-2 PF06920.13 ORY06843.1 - 0.003 16.3 1.0 0.003 16.3 1.0 1.9 1 1 1 2 2 2 1 Dock homology region 2 Spatacsin_C PF14649.6 ORY06843.1 - 0.0069 15.5 11.3 2.7 7.0 8.3 3.1 1 1 1 2 2 2 2 Spatacsin C-terminus TPR_2 PF07719.17 ORY06843.1 - 0.014 15.5 14.3 0.33 11.2 0.4 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY06843.1 - 0.025 14.6 5.7 1.3 9.2 0.1 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1851 PF08906.11 ORY06843.1 - 0.12 12.3 1.2 0.56 10.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1851) TPR_6 PF13174.6 ORY06843.1 - 0.16 12.7 15.5 8 7.3 0.3 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 ORY06843.1 - 0.2 11.7 12.8 2.4 8.3 3.5 4.2 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 ORY06843.1 - 0.21 11.6 7.3 3.6 7.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY06843.1 - 1 10.3 5.9 10 7.2 0.0 4.4 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY06843.1 - 1.1 9.2 17.4 4.6 7.2 0.8 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY06843.1 - 2.2 8.7 17.9 9.7 6.7 0.1 5.9 6 2 1 7 7 7 0 Tetratricopeptide repeat ADH_N PF08240.12 ORY06844.1 - 5.2e-30 103.5 5.1 1.2e-29 102.4 5.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06844.1 - 1.1e-27 96.5 0.9 1.6e-27 96.0 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06844.1 - 5.1e-09 37.3 0.0 1e-08 36.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06844.1 - 0.0028 17.1 0.4 0.0059 16.1 0.4 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06844.1 - 0.004 16.5 0.3 0.0069 15.8 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06844.1 - 0.01 15.1 1.2 0.017 14.4 1.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 ORY06845.1 - 4.6e-33 113.3 2.0 9.9e-33 112.3 2.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06845.1 - 3.6e-27 94.9 0.1 5.4e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06845.1 - 1.3e-05 26.3 0.0 2.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06845.1 - 0.0019 17.7 0.2 0.0033 16.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 ORY06845.1 - 0.0081 15.5 0.6 0.013 14.8 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY06845.1 - 0.012 15.0 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.18 ORY06846.1 - 8.5e-33 113.4 0.0 1.4e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06846.1 - 3.4e-25 88.4 0.0 6.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06846.1 - 5.3e-17 62.0 0.1 1.5e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06846.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z TPP_enzyme_N PF02776.18 ORY06847.1 - 7.2e-38 129.9 0.1 3.9e-32 111.2 0.0 3.0 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY06847.1 - 6.9e-17 61.6 0.1 1.6e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06847.1 - 4.6e-14 52.3 0.0 1.2e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_M PF00205.22 ORY06848.1 - 2.8e-25 88.6 0.0 5.1e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06848.1 - 4.9e-17 62.1 0.1 1.2e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 ORY06848.1 - 6.2e-09 35.7 0.1 1.2e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06848.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z TPP_enzyme_N PF02776.18 ORY06849.1 - 4.4e-32 111.1 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06849.1 - 3.4e-25 88.4 0.0 6.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06849.1 - 6.3e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06849.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z TPP_enzyme_N PF02776.18 ORY06850.1 - 4.3e-32 111.1 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06850.1 - 8.1e-25 87.2 0.0 1.5e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06850.1 - 6.3e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06850.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z TPP_enzyme_N PF02776.18 ORY06851.1 - 4.2e-32 111.1 0.0 7.1e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06851.1 - 1.3e-19 70.3 0.0 2.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06851.1 - 6.1e-17 61.8 0.1 1.5e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06851.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z TPP_enzyme_N PF02776.18 ORY06852.1 - 4.4e-32 111.1 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06852.1 - 3.4e-25 88.4 0.0 6.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06852.1 - 6.3e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06852.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z ADH_N PF08240.12 ORY06853.1 - 3.9e-34 116.8 2.2 7.5e-34 115.9 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06853.1 - 9.5e-28 96.8 0.3 1.8e-27 95.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06853.1 - 0.00032 20.2 0.3 0.00059 19.3 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06853.1 - 0.01 15.2 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06853.1 - 0.024 13.9 1.1 0.042 13.1 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY06853.1 - 0.084 13.9 0.0 0.16 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPP_enzyme_N PF02776.18 ORY06854.1 - 4.4e-32 111.1 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06854.1 - 3.4e-25 88.4 0.0 6.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06854.1 - 6.3e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06854.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z ADH_N PF08240.12 ORY06855.1 - 2.7e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06855.1 - 7.2e-28 97.2 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06855.1 - 1.7e-06 29.1 0.1 3e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06855.1 - 0.00021 20.8 0.3 0.00046 19.7 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06855.1 - 0.0075 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06855.1 - 0.021 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 ORY06855.1 - 0.086 12.8 0.1 0.44 10.5 0.0 2.2 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORY06856.1 - 6.5e-28 97.3 0.3 1.1e-27 96.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY06856.1 - 2.6e-25 88.4 0.8 6.1e-25 87.2 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY06856.1 - 1.5e-06 29.3 0.1 2.7e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06856.1 - 0.00019 20.9 0.3 0.00043 19.8 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06856.1 - 0.0072 15.7 0.2 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06856.1 - 0.023 14.0 1.5 0.038 13.3 1.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 ORY06856.1 - 0.15 11.9 0.0 0.6 10.0 0.0 2.1 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase TPP_enzyme_N PF02776.18 ORY06857.1 - 4.4e-32 111.1 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06857.1 - 3.4e-25 88.4 0.0 6.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06857.1 - 6.3e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06857.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z DDE_Tnp_1_7 PF13843.6 ORY06858.1 - 0.0045 16.3 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 2 Transposase IS4 ADH_N PF08240.12 ORY06859.1 - 3.9e-34 116.8 2.2 7.5e-34 115.9 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06859.1 - 9.4e-28 96.8 0.3 1.8e-27 95.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06859.1 - 0.00032 20.2 0.3 0.00059 19.3 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06859.1 - 0.0098 15.3 0.2 0.02 14.2 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06859.1 - 0.024 14.0 1.1 0.042 13.1 1.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ORY06859.1 - 0.071 14.2 0.0 0.14 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPP_enzyme_N PF02776.18 ORY06860.1 - 4.4e-32 111.1 0.0 7.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06860.1 - 3.4e-25 88.4 0.0 6.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06860.1 - 6.2e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06860.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z ADH_N PF08240.12 ORY06861.1 - 2.8e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06861.1 - 7.3e-28 97.1 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06861.1 - 3.4e-06 28.1 0.0 6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06861.1 - 0.00024 20.6 0.3 0.00046 19.7 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06861.1 - 0.0076 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06861.1 - 0.022 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPP_enzyme_N PF02776.18 ORY06862.1 - 4.3e-32 111.1 0.0 7.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06862.1 - 3.4e-25 88.4 0.0 6.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06862.1 - 6.3e-17 61.8 0.1 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Spore-coat_CotZ PF10612.9 ORY06862.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z ADH_N PF08240.12 ORY06863.1 - 2.8e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06863.1 - 7.3e-28 97.1 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06863.1 - 3.4e-06 28.1 0.0 6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06863.1 - 0.00024 20.6 0.3 0.00046 19.7 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06863.1 - 0.0076 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06863.1 - 0.022 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 ORY06864.1 - 2.8e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06864.1 - 7.3e-28 97.1 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06864.1 - 3.4e-06 28.1 0.0 6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06864.1 - 0.00024 20.6 0.3 0.00046 19.7 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06864.1 - 0.0076 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06864.1 - 0.022 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 ORY06865.1 - 2.8e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06865.1 - 7.3e-28 97.1 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06865.1 - 3.4e-06 28.1 0.0 6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06865.1 - 0.00024 20.6 0.3 0.00046 19.7 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06865.1 - 0.0076 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06865.1 - 0.022 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 ORY06866.1 - 5.9e-28 97.4 0.3 1e-27 96.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY06866.1 - 1.3e-23 82.9 0.6 2.9e-23 81.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY06866.1 - 2.7e-06 28.5 0.0 4.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06866.1 - 0.00021 20.8 0.3 0.0004 19.9 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06866.1 - 0.0066 15.8 0.2 0.014 14.8 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06866.1 - 0.02 14.2 1.3 0.032 13.5 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPP_enzyme_N PF02776.18 ORY06867.1 - 3.8e-34 117.8 0.0 6.6e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY06867.1 - 3.2e-24 85.2 0.0 5.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY06867.1 - 4.7e-16 59.0 0.0 1.1e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain p31comet PF06581.12 ORY06867.1 - 0.085 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding ADH_zinc_N PF00107.26 ORY06868.1 - 1.9e-48 163.7 1.7 2.2e-27 95.6 0.3 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY06868.1 - 1.4e-34 118.3 2.8 2.6e-34 117.4 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY06868.1 - 1.7e-08 35.6 0.9 8.5e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06868.1 - 0.0004 19.9 1.2 0.0007 19.1 0.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06868.1 - 0.01 15.2 0.2 0.024 14.0 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06868.1 - 0.028 13.7 1.2 0.054 12.8 1.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tir_receptor_M PF03549.14 ORY06868.1 - 0.087 13.2 0.0 26 5.2 0.0 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain Parecho_VpG PF06344.11 ORY06868.1 - 0.15 12.7 0.9 34 5.4 0.1 2.6 2 0 0 2 2 2 0 Parechovirus Genome-linked protein HrpB_C PF08482.10 ORY06868.1 - 0.2 12.1 0.0 37 4.7 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal ADH_N PF08240.12 ORY06869.1 - 2.8e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06869.1 - 7.3e-28 97.2 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06869.1 - 3.4e-06 28.1 0.0 6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06869.1 - 0.00024 20.7 0.3 0.00046 19.7 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06869.1 - 0.0076 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06869.1 - 0.022 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 ORY06870.1 - 2.8e-34 117.3 2.2 5.5e-34 116.3 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06870.1 - 7.3e-28 97.2 0.3 1.2e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06870.1 - 3.4e-06 28.1 0.0 6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY06870.1 - 0.00024 20.7 0.3 0.00046 19.7 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY06870.1 - 0.0076 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY06870.1 - 0.022 14.1 1.3 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 ORY06871.1 - 1e-08 35.0 0.3 8.8e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY06871.1 - 8e-07 29.1 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY06871.1 - 0.031 15.3 0.0 0.038 15.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY06871.1 - 0.074 12.9 0.0 0.74 9.7 0.0 2.4 2 1 0 3 3 3 0 N-terminal domain of oxidoreductase DNA_pol_A_exo1 PF01612.20 ORY06872.1 - 1.9e-19 70.1 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Exonuc_VII_S PF02609.16 ORY06872.1 - 0.00014 21.8 0.4 0.00026 21.0 0.4 1.4 1 0 0 1 1 1 1 Exonuclease VII small subunit adh_short_C2 PF13561.6 ORY06937.1 - 1.1e-57 195.3 0.1 1.5e-57 194.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY06937.1 - 2.1e-48 164.4 0.2 2.6e-48 164.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY06937.1 - 3e-12 46.8 0.0 4.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY06937.1 - 0.00013 22.3 0.2 0.00023 21.4 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ORY06937.1 - 0.00021 21.8 0.4 0.00043 20.8 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ORY06937.1 - 0.00038 20.0 0.1 0.00048 19.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family His_biosynth PF00977.21 ORY06937.1 - 0.0011 18.5 0.4 0.0025 17.3 0.3 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein Shikimate_DH PF01488.20 ORY06937.1 - 0.0018 18.3 0.6 0.0072 16.4 0.6 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORY06937.1 - 0.091 12.6 0.4 0.13 12.1 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ORY06937.1 - 0.095 12.8 0.6 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pkinase PF00069.25 ORY06938.1 - 1.6e-09 37.6 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORY06939.1 - 2.2e-57 194.4 0.0 2.7e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY06939.1 - 1.9e-32 112.6 0.0 2.7e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY06939.1 - 5.4e-09 35.8 0.0 3.6e-08 33.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY06939.1 - 0.003 16.4 1.1 0.044 12.6 0.0 2.1 1 1 1 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY06939.1 - 0.005 15.9 0.1 0.0081 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 ORY06939.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY06939.1 - 0.027 14.4 0.0 1.4 8.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY06939.1 - 0.069 12.8 0.7 4.7 6.8 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SCNM1_acidic PF15805.5 ORY06941.1 - 1.1e-14 53.8 0.1 2.3e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 zf-SCNM1 PF15803.5 ORY06941.1 - 9e-11 41.2 0.3 1.6e-10 40.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 MAGE_N PF12440.8 ORY06941.1 - 0.0059 17.3 0.7 0.014 16.0 0.7 1.7 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal DAG1 PF05454.11 ORY06941.1 - 0.27 10.6 5.2 0.042 13.2 0.6 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1748 PF08520.10 ORY06942.1 - 1.9e-29 101.4 0.1 2.1e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FNIP_M PF14637.6 ORY06943.1 - 2e-59 201.3 0.0 3.2e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 ORY06943.1 - 9.3e-39 133.0 0.0 1.8e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 ORY06943.1 - 1.1e-10 42.8 1.7 1.1e-10 42.8 1.7 3.8 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus RRM_1 PF00076.22 ORY06944.1 - 2.2e-37 126.7 0.0 4.8e-18 64.7 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY06944.1 - 1.8e-16 60.0 1.0 2.7e-07 30.6 0.0 3.3 3 0 0 3 3 3 3 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.13 ORY06944.1 - 0.0049 16.8 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 ORY06944.1 - 0.05 13.7 0.0 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM_2 PF14605.6 ORY06944.1 - 0.28 11.2 0.8 2.3 8.3 0.1 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF202 PF02656.15 ORY06945.1 - 0.00014 22.2 1.1 0.00014 22.2 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) UPRTase PF14681.6 ORY06946.1 - 6.2e-81 270.8 0.0 7.6e-81 270.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY06946.1 - 0.0019 17.7 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 ORY06946.1 - 0.17 11.9 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Perilipin PF03036.16 ORY06947.1 - 7.5e-12 45.0 0.0 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Perilipin family TMEM18 PF14770.6 ORY06948.1 - 3e-31 107.9 7.1 3.9e-31 107.5 7.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Glucos_trans_II PF14264.6 ORY06948.1 - 0.011 15.1 5.1 0.011 15.1 5.1 1.9 1 1 0 2 2 2 0 Glucosyl transferase GtrII FtsX PF02687.21 ORY06948.1 - 8.5 6.9 10.2 56 4.3 10.2 2.0 1 1 0 1 1 1 0 FtsX-like permease family Methyltransf_31 PF13847.6 ORY06949.1 - 6.5e-17 61.7 0.0 8.5e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY06949.1 - 6.9e-15 55.5 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY06949.1 - 9.1e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY06949.1 - 1.5e-13 51.3 0.0 2.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY06949.1 - 3.5e-11 42.9 0.0 4.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY06949.1 - 4e-09 36.5 0.0 6.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ORY06949.1 - 1.8e-05 24.5 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 ORY06949.1 - 0.00071 19.2 0.0 0.0025 17.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY06949.1 - 0.002 17.5 0.1 0.0031 16.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 ORY06949.1 - 0.012 15.6 0.0 0.037 14.0 0.0 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PLA2G12 PF06951.11 ORY06951.1 - 2.4e-06 27.6 14.9 4.4e-06 26.7 14.9 1.6 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF2370 PF10176.9 ORY06952.1 - 2.2e-61 207.4 7.6 1.6e-53 181.7 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2370) DUF202 PF02656.15 ORY06952.1 - 0.19 12.2 0.7 0.76 10.3 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Kinesin PF00225.23 ORY06953.1 - 2.5e-103 345.5 0.0 3.1e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY06953.1 - 9.2e-22 77.6 0.0 2.1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DPPIV_N PF00930.21 ORY06954.1 - 1.8e-61 207.9 1.9 3.6e-61 206.9 1.2 1.7 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY06954.1 - 4.5e-54 183.1 0.0 9.2e-54 182.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY06954.1 - 3.8e-06 26.7 0.1 3.4e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 ORY06954.1 - 1.2e-05 25.0 0.0 3.7e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 ORY06954.1 - 2.2e-05 24.2 0.0 7.3e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 ORY06954.1 - 9.8e-05 23.1 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY06954.1 - 0.00069 19.3 0.2 0.0022 17.7 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY06954.1 - 0.0013 18.1 1.0 0.005 16.1 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY06954.1 - 0.015 15.1 0.2 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ORY06954.1 - 0.065 13.1 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 ORY06954.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BCDHK_Adom3 PF10436.9 ORY06955.1 - 8.8e-66 220.7 0.0 1e-64 217.3 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY06955.1 - 6.7e-14 52.4 0.0 1.8e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY06955.1 - 0.00062 19.6 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 ORY06955.1 - 0.016 15.0 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family SPRY PF00622.28 ORY06956.1 - 3.8e-19 69.0 0.1 8.2e-19 67.9 0.1 1.6 1 1 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 ORY06956.1 - 2.7e-09 36.7 7.8 5e-09 35.9 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY06956.1 - 0.001 18.9 10.5 0.0022 17.8 10.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zw10 PF06248.13 ORY06957.1 - 3.4e-57 194.3 20.9 4e-57 194.0 20.9 1.0 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Elicitin PF00964.17 ORY06957.1 - 0.11 12.6 0.2 4.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Elicitin YqgF PF14639.6 ORY06957.1 - 0.15 11.8 1.5 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 Zw10 PF06248.13 ORY06958.1 - 3.8e-06 25.8 2.0 3.8e-06 25.8 2.0 1.7 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 ORY06958.1 - 9.2e-06 25.5 3.2 1.4e-05 24.9 3.2 1.3 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Rdx PF10262.9 ORY06959.1 - 2.4e-32 111.0 0.0 3.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Rdx family SPATA24 PF15175.6 ORY06959.1 - 0.013 15.4 1.2 0.017 15.1 1.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 ThrE PF06738.12 ORY06960.1 - 8.8e-59 198.8 19.8 4.1e-54 183.5 3.4 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY06960.1 - 2.4e-14 53.6 31.9 1.3e-11 44.7 10.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Clc-like PF07062.12 ORY06960.1 - 0.00016 21.3 1.5 0.00031 20.3 0.9 1.9 1 1 0 1 1 1 1 Clc-like MBOAT PF03062.19 ORY06961.1 - 4.7e-32 111.7 23.4 7.3e-32 111.1 21.1 2.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY06961.1 - 0.0031 17.8 0.7 0.018 15.3 0.7 2.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PAS_9 PF13426.7 ORY06962.1 - 1.3e-32 112.1 0.0 2.1e-15 56.8 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ORY06962.1 - 8.9e-28 96.4 0.0 6.2e-16 58.5 0.0 4.5 3 1 0 3 3 3 3 PAS fold PAS PF00989.25 ORY06962.1 - 2.4e-22 79.0 0.0 6.1e-09 35.9 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 ORY06962.1 - 2.5e-17 63.1 0.0 3.9e-06 27.1 0.0 3.3 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORY06962.1 - 8.4e-13 48.4 0.0 1.1e-06 28.8 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 ORY06962.1 - 1e-05 26.1 0.0 0.24 12.1 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 ORY06962.1 - 0.0028 17.6 0.0 0.66 10.1 0.0 2.6 2 0 0 2 2 2 1 PAS domain NUDIX_2 PF13869.6 ORY06963.1 - 1.3e-83 279.2 0.1 1.5e-83 279.1 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF1759 PF03564.15 ORY06964.1 - 0.06 13.3 0.5 0.084 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) PARP PF00644.20 ORY06965.1 - 2.5e-63 213.2 0.0 3.6e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 ORY06965.1 - 4.3e-41 140.2 0.0 7.4e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 ORY06965.1 - 2.4e-19 69.2 1.2 8.8e-18 64.1 0.9 2.6 2 0 0 2 2 2 1 WGR domain FKBP_C PF00254.28 ORY06966.1 - 4e-33 113.6 0.0 4.9e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FHA PF00498.26 ORY06967.1 - 9.8e-10 38.7 0.3 1.7e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 ORY06967.1 - 0.00014 22.0 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 FHA domain 3Beta_HSD PF01073.19 ORY06968.1 - 6e-42 143.6 0.1 7.7e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY06968.1 - 2.4e-27 96.0 0.1 4.1e-27 95.2 0.0 1.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY06968.1 - 1.8e-12 47.3 0.0 3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY06968.1 - 2.3e-11 43.3 0.0 5.8e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY06968.1 - 2.2e-09 36.9 0.1 3.3e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 ORY06968.1 - 4.9e-08 33.1 0.0 1e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY06968.1 - 9.9e-08 31.5 0.1 4.9e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ORY06968.1 - 1.5e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ORY06968.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase AvrLm4-7 PF18661.1 ORY06968.1 - 0.038 15.0 0.1 0.092 13.8 0.1 1.7 1 1 0 1 1 1 0 Avirulence Effector AvrLm4-7 TrkA_N PF02254.18 ORY06968.1 - 0.14 12.5 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 ORY06968.1 - 0.16 12.0 0.0 0.41 10.6 0.0 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding Ceramidase PF05875.12 ORY06969.1 - 3.5e-37 128.2 4.0 3.8e-37 128.2 4.0 1.0 1 0 0 1 1 1 1 Ceramidase Ser_hydrolase PF06821.13 ORY06970.1 - 2.1e-11 44.0 0.0 2.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 ORY06970.1 - 1.7e-05 24.6 0.0 5.8e-05 22.8 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY06970.1 - 2.6e-05 25.0 0.0 0.00011 22.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY06970.1 - 0.00048 19.5 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 ORY06970.1 - 0.00074 18.6 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 ORY06970.1 - 0.001 18.9 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY06970.1 - 0.0066 15.8 0.0 0.042 13.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF3530 PF12048.8 ORY06970.1 - 0.04 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) LIDHydrolase PF10230.9 ORY06970.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CRAL_TRIO PF00650.20 ORY06971.1 - 2.2e-36 125.0 0.0 3.4e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY06971.1 - 6.5e-10 39.1 0.1 1.5e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY06971.1 - 4.1e-06 27.0 0.0 6.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Adeno_hexon_C PF03678.14 ORY06971.1 - 0.042 13.3 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain CBM9_1 PF06452.11 ORY06972.1 - 1.4e-08 34.9 0.2 1.5e-07 31.5 0.0 2.5 4 0 0 4 4 4 1 Carbohydrate family 9 binding domain-like BTD PF09270.10 ORY06973.1 - 3e-27 95.7 0.0 5.9e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 ORY06973.1 - 7.1e-24 85.2 2.6 7.1e-24 85.2 2.6 3.3 3 1 0 3 3 3 1 LAG1, DNA binding Aminotran_1_2 PF00155.21 ORY06975.1 - 1e-42 146.7 0.0 1.4e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY06975.1 - 0.0018 16.9 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MOR2-PAG1_C PF14225.6 ORY06975.1 - 0.049 13.5 0.0 0.67 9.8 0.0 2.4 3 0 0 3 3 3 0 Cell morphogenesis C-terminal Sec20 PF03908.13 ORY06975.1 - 0.08 12.9 0.4 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 Sec20 LON_substr_bdg PF02190.16 ORY06977.1 - 5.3e-31 108.1 0.0 9.4e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 ORY06977.1 - 3.8e-15 55.8 24.9 8.6e-08 32.2 9.9 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORY06977.1 - 4.8e-14 51.9 22.7 2.5e-10 40.0 10.7 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY06977.1 - 6.2e-13 48.5 26.6 5.1e-08 32.8 4.4 3.9 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY06977.1 - 1.6e-10 40.7 21.7 3.1e-08 33.4 7.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY06977.1 - 6.8e-10 38.7 23.5 1.1e-06 28.4 6.7 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY06977.1 - 9.4e-09 35.1 24.9 1.6e-06 27.9 11.1 2.8 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 ORY06977.1 - 3e-07 30.7 10.1 3e-07 30.7 10.1 3.6 4 0 0 4 4 4 2 Ring finger domain Prok-RING_4 PF14447.6 ORY06977.1 - 2.7e-06 27.1 23.0 7.5e-06 25.7 7.4 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY06977.1 - 4.2e-05 23.6 21.9 0.00071 19.7 7.6 2.6 2 1 0 2 2 2 2 zinc RING finger of MSL2 U-box PF04564.15 ORY06977.1 - 0.0033 17.5 0.3 2 8.7 0.1 2.6 2 0 0 2 2 2 2 U-box domain zf-rbx1 PF12678.7 ORY06977.1 - 0.0076 16.5 4.7 0.0076 16.5 4.7 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-P11 PF03854.14 ORY06977.1 - 0.016 14.9 6.0 0.016 14.9 6.0 2.4 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 ORY06977.1 - 0.019 14.7 3.7 0.019 14.7 3.7 3.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Proteasome PF00227.26 ORY06978.1 - 1.1e-61 207.6 0.1 1.6e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY06978.1 - 6.4e-11 41.7 0.1 2.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TPT PF03151.16 ORY06979.1 - 3.4e-22 79.1 33.3 3.9e-22 79.0 33.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY06979.1 - 5.5e-08 33.1 39.5 7.5e-06 26.2 11.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3042 PF11240.8 ORY06979.1 - 1 9.4 2.8 6.6 6.8 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) WD40 PF00400.32 ORY06980.1 - 8.9e-14 51.7 2.4 0.36 11.8 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Lactonase PF10282.9 ORY06980.1 - 5.3e-06 25.9 0.0 1.7e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 ORY06980.1 - 7.8e-05 22.9 0.0 2.6 8.4 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 ORY06980.1 - 0.024 14.2 0.0 2.9 7.4 0.0 3.0 1 1 3 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 ORY06980.1 - 0.037 14.0 0.2 3.4 7.7 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat LPD24 PF18839.1 ORY06980.1 - 0.12 12.7 0.1 33 4.8 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Vac7 PF12751.7 ORY06981.1 - 2.1e-12 47.2 0.0 3.3e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 PWWP PF00855.17 ORY06982.1 - 6.7e-09 36.0 1.9 3.1e-08 33.9 0.0 2.6 2 1 0 2 2 2 1 PWWP domain RBB1NT PF08169.11 ORY06982.1 - 2.9e-08 33.8 0.0 9.8e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 RBB1NT (NUC162) domain Proton_antipo_M PF00361.20 ORY06983.1 - 2.8e-62 210.6 16.2 2.8e-62 210.6 16.2 1.3 1 1 0 1 1 1 1 Proton-conducting membrane transporter MafB PF06255.13 ORY06983.1 - 0.063 12.7 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB DUF2619 PF10942.8 ORY06983.1 - 3.2 7.9 8.4 9.7 6.4 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) FOXP-CC PF16159.5 ORY06984.1 - 0.00064 20.3 0.3 0.00084 19.9 0.3 1.3 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY06984.1 - 0.023 15.2 0.4 0.044 14.3 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY06984.1 - 0.066 14.1 0.3 0.2 12.6 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf_ZIC PF18366.1 ORY06984.1 - 0.067 13.3 0.6 0.21 11.7 0.6 1.9 1 1 0 1 1 1 0 Zic proteins zinc finger domain DUF2110 PF09883.9 ORY06984.1 - 0.16 11.5 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) DUF1769 PF08588.10 ORY06986.1 - 2.2e-13 50.2 0.1 4.3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Polysacc_deac_1 PF01522.21 ORY06987.1 - 2e-31 108.4 0.1 3.6e-31 107.6 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Cloacin_immun PF03513.14 ORY06987.1 - 0.0013 19.1 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Cloacin immunity protein Herpes_capsid PF06112.11 ORY06987.1 - 0.73 9.9 8.2 1.2 9.2 8.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein His_Phos_1 PF00300.22 ORY06988.1 - 1e-30 106.9 0.0 1.3e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C14 PF00656.22 ORY06989.1 - 5.5e-60 203.4 0.0 7.5e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Mem_trans PF03547.18 ORY06989.1 - 0.031 12.7 0.1 0.052 11.9 0.1 1.3 1 1 0 1 1 1 0 Membrane transport protein zf-C2H2 PF00096.26 ORY06990.1 - 4.7e-06 26.8 10.6 0.005 17.2 0.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY06990.1 - 5.9e-06 26.8 2.8 0.005 17.4 0.1 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORY06990.1 - 0.031 14.7 2.4 0.031 14.7 2.4 2.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY06990.1 - 0.043 14.7 9.2 0.38 11.7 0.0 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY06990.1 - 0.085 13.0 2.2 0.093 12.9 2.2 1.1 1 0 0 1 1 1 0 Aberrant zinc-finger Macro_2 PF14519.6 ORY06992.1 - 9.1e-10 38.3 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 ORY06992.1 - 3.9e-05 23.7 0.0 8.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Macro domain Cg6151-P PF10233.9 ORY06993.1 - 3e-24 85.5 14.3 3.7e-24 85.2 14.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P OSTMP1 PF09777.9 ORY06993.1 - 0.37 10.1 0.1 0.37 10.1 0.1 1.9 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor MRAP PF15183.6 ORY06993.1 - 1.1 9.3 10.8 1.1 9.2 0.5 2.6 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family zf-H2C2_2 PF13465.6 ORY06996.1 - 3.3e-14 52.5 7.2 3.3e-10 39.9 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY06996.1 - 1e-11 44.6 18.0 4.9e-06 26.7 1.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY06996.1 - 2e-09 37.5 11.4 0.00012 22.6 4.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY06996.1 - 2.6e-07 30.8 3.6 0.0011 19.2 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY06996.1 - 9.2e-06 25.4 7.7 0.0045 16.8 0.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 ORY06996.1 - 9.6e-06 25.5 4.2 0.012 15.6 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY06996.1 - 4.6e-05 23.6 3.6 0.0012 19.0 3.7 2.1 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 ORY06996.1 - 0.00021 21.3 0.8 0.16 12.1 0.1 2.2 1 1 1 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 ORY06996.1 - 0.0013 19.0 3.5 0.023 15.0 0.5 2.1 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.14 ORY06996.1 - 0.0053 16.7 0.3 2 8.4 0.0 2.2 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_8 PF15909.5 ORY06996.1 - 0.0082 16.4 2.4 0.01 16.1 2.4 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon DZR PF12773.7 ORY06996.1 - 0.0088 16.1 0.4 0.013 15.5 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon Prok-RING_1 PF14446.6 ORY06996.1 - 0.032 14.1 0.2 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PyrI_C PF02748.15 ORY06996.1 - 0.042 13.8 1.3 0.94 9.4 0.1 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_9 PF16293.5 ORY06996.1 - 0.046 13.6 0.2 0.33 10.8 0.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-LITAF-like PF10601.9 ORY06996.1 - 0.048 13.9 0.9 0.32 11.3 0.1 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain C1_4 PF07975.12 ORY06996.1 - 0.054 13.7 4.8 0.44 10.8 0.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain FANCL_C PF11793.8 ORY06996.1 - 0.054 13.7 0.8 0.43 10.8 0.1 2.1 1 1 0 2 2 2 0 FANCL C-terminal domain DUF2321 PF10083.9 ORY06996.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-C2H2_12 PF18112.1 ORY06996.1 - 0.15 12.6 2.7 2.2 8.8 1.1 2.5 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 ORY06996.1 - 0.33 11.0 6.1 2.2 8.4 0.9 2.5 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 ORY06996.1 - 0.51 10.5 5.4 3.1 8.0 0.1 2.6 3 0 0 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.16 ORY06996.1 - 0.68 10.2 9.7 4 7.7 3.0 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-RING_7 PF02591.15 ORY06996.1 - 0.69 10.1 5.3 6 7.1 0.1 2.4 2 1 0 2 2 2 0 C4-type zinc ribbon domain zf-C2HE PF16278.5 ORY06996.1 - 0.99 9.9 5.1 3.8 8.0 1.0 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ABC_tran PF00005.27 ORY07061.1 - 1.1e-05 26.0 3.7 1.1e-05 26.0 3.7 2.1 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY07061.1 - 0.00061 19.7 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 ORY07061.1 - 0.049 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY07061.1 - 0.057 13.3 1.4 0.14 12.0 0.2 2.0 1 1 1 2 2 2 0 RsgA GTPase AvrM-A PF18241.1 ORY07061.1 - 0.072 13.5 0.4 0.072 13.5 0.4 1.5 2 0 0 2 2 2 0 Flax-rust effector AvrM-A AAA_29 PF13555.6 ORY07061.1 - 0.11 12.3 1.4 0.17 11.6 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY07061.1 - 0.11 12.5 0.4 0.38 10.9 0.4 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY07061.1 - 0.15 11.7 0.9 0.33 10.6 0.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 ORY07061.1 - 0.23 10.8 2.1 0.52 9.7 2.1 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY07061.1 - 0.87 10.1 7.9 2.5 8.6 6.8 2.2 2 1 0 2 2 2 0 AAA domain AMP-binding PF00501.28 ORY07062.1 - 0 1702.2 0.0 2.5e-89 299.8 0.0 6.2 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 ORY07062.1 - 0 1009.1 0.1 1.1e-60 205.6 0.4 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 ORY07062.1 - 1.7e-65 217.3 11.1 9.9e-12 45.1 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORY07062.1 - 1.5e-12 48.3 1.3 0.23 12.5 0.0 6.6 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain Transferase PF02458.15 ORY07062.1 - 0.0022 16.7 0.5 0.89 8.1 0.2 4.3 6 0 0 6 6 6 1 Transferase family TRAM_2 PF18693.1 ORY07062.1 - 0.14 12.4 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 TRAM domain CAAP1 PF15335.6 ORY07062.1 - 0.32 11.6 1.9 0.91 10.1 0.1 2.9 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Fasciclin PF02469.22 ORY07063.1 - 8.5e-48 161.8 0.0 1.3e-25 90.1 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain MIF PF01187.18 ORY07064.1 - 1.1e-25 90.2 0.0 1.2e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 ORY07064.1 - 5.2e-05 23.1 0.0 0.0029 17.5 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme DSPc PF00782.20 ORY07065.1 - 2.3e-38 131.0 0.0 3.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY07065.1 - 0.0019 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Bunya_NS-S PF01104.17 ORY07065.1 - 0.75 9.6 4.4 0.84 9.5 0.7 2.2 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s Elong-fact-P_C PF09285.11 ORY07066.1 - 3.9e-14 52.1 0.1 1.1e-13 50.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 ORY07066.1 - 3.4e-12 46.2 0.1 6.5e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 ORY07066.1 - 5.2e-11 42.4 1.1 8.6e-11 41.7 1.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Csm1_B PF18211.1 ORY07066.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Csm1 subunit domain B UreE_C PF05194.12 ORY07067.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain EF-hand_1 PF00036.32 ORY07068.1 - 2.2e-41 136.3 15.4 2.4e-10 39.2 1.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY07068.1 - 3.6e-36 123.5 4.9 6.9e-19 68.1 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORY07068.1 - 5.9e-31 106.1 13.4 1.4e-14 53.6 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ORY07068.1 - 7.7e-31 103.4 10.3 2.9e-09 36.1 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY07068.1 - 1.5e-26 90.7 13.5 9.6e-07 28.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY07068.1 - 2.9e-16 59.5 0.3 8.1e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY07068.1 - 8.2e-10 38.6 1.8 7.1e-05 22.7 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY07068.1 - 6.3e-09 36.2 0.1 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ORY07068.1 - 4e-06 26.9 2.7 0.021 15.0 0.5 3.1 1 1 3 4 4 4 2 Dockerin type I domain EF-hand_11 PF08976.11 ORY07068.1 - 4.3e-06 27.5 0.0 0.00022 22.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 ORY07068.1 - 3.7e-05 23.7 0.5 0.12 12.4 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 ORY07068.1 - 6.5e-05 23.6 0.4 0.47 11.3 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) EFhand_Ca_insen PF08726.10 ORY07068.1 - 0.00015 21.8 1.4 0.00086 19.4 0.2 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 ORY07068.1 - 0.0012 19.3 0.0 0.43 11.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Caleosin PF05042.13 ORY07068.1 - 0.0018 18.2 1.4 0.81 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 ORY07068.1 - 0.0023 17.9 0.7 0.45 10.5 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 ORY07068.1 - 0.0045 17.3 0.7 1.4 9.3 0.1 2.8 2 1 1 3 3 3 1 RNA polymerase Rpb4 SurA_N_2 PF13623.6 ORY07068.1 - 0.0045 16.9 0.9 0.89 9.4 0.1 2.3 1 1 1 2 2 2 1 SurA N-terminal domain MotA_activ PF09114.10 ORY07068.1 - 0.0076 16.3 0.2 0.11 12.6 0.0 2.3 2 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 ORY07068.1 - 0.013 15.1 2.9 0.015 14.9 2.9 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF5580 PF17743.1 ORY07068.1 - 0.018 13.6 0.0 0.018 13.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 ORY07068.1 - 0.041 14.2 0.2 9.5 6.6 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 ORY07068.1 - 0.048 12.8 0.1 1.3 8.1 0.1 2.3 1 1 1 2 2 2 0 Cache domain MecA_N PF05223.11 ORY07068.1 - 0.057 13.7 0.5 0.12 12.7 0.2 1.6 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain RuvA_C PF07499.13 ORY07068.1 - 0.14 12.7 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain GPHH PF16905.5 ORY07068.1 - 0.14 11.9 0.0 12 5.7 0.0 3.3 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated Spore_III_AB PF09548.10 ORY07068.1 - 0.15 12.1 0.6 0.31 11.1 0.6 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FGAR-AT_linker PF18072.1 ORY07068.1 - 0.16 12.6 0.3 5.6 7.6 0.0 2.6 2 2 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain SapB_1 PF05184.15 ORY07068.1 - 0.82 9.8 3.8 27 4.9 0.1 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 Ank_5 PF13857.6 ORY07069.1 - 0.00062 20.0 0.1 0.081 13.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY07069.1 - 0.00078 20.0 0.0 0.00094 19.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PCP PF02429.15 ORY07069.1 - 0.0062 16.9 0.0 0.0062 16.9 0.0 1.0 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein Ank_3 PF13606.6 ORY07069.1 - 0.03 14.9 0.0 1.1 10.0 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 ORY07069.1 - 0.059 14.0 0.0 0.096 13.3 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ribosomal_L39 PF00832.20 ORY07069.1 - 0.098 12.3 0.3 0.18 11.5 0.3 1.5 1 1 1 2 2 2 0 Ribosomal L39 protein DUF262 PF03235.14 ORY07070.1 - 1.8e-15 57.8 0.4 1.4e-14 54.8 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function DUF262 Acatn PF13000.7 ORY07070.1 - 0.073 11.6 0.3 0.093 11.2 0.3 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Sugar_tr PF00083.24 ORY07071.1 - 4.7e-47 160.9 16.0 9.9e-45 153.2 16.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY07071.1 - 1.3e-15 57.2 31.6 4.4e-08 32.4 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.11 ORY07072.1 - 5e-14 53.0 0.0 5.5e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY07072.1 - 1.1e-06 28.4 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1963 PF09234.10 ORY07073.1 - 3.5e-17 63.6 0.2 4.6e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) DUF1279 PF06916.13 ORY07074.1 - 9.4e-12 45.3 0.0 1.1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2255 PF10012.9 ORY07074.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) FYRN PF05964.14 ORY07076.1 - 4.7e-20 71.2 0.3 8.2e-20 70.4 0.3 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY07076.1 - 7.5e-15 54.9 0.0 2.3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus Lge1 PF11488.8 ORY07076.1 - 0.091 13.0 3.4 0.23 11.6 3.4 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 UL17 PF17640.2 ORY07076.1 - 0.15 12.1 2.3 0.37 10.8 2.3 1.6 1 0 0 1 1 1 0 Uncharacterized UL17 DUF724 PF05266.14 ORY07076.1 - 6.9 6.4 9.0 16 5.2 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NDK PF00334.19 ORY07077.1 - 1.3e-51 174.1 0.0 1.5e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase EF-hand_7 PF13499.6 ORY07079.1 - 2.7e-26 91.8 6.5 1.9e-18 66.7 0.7 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY07079.1 - 7.2e-25 84.8 4.3 1.5e-06 27.7 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 ORY07079.1 - 1.1e-24 84.0 12.5 3.6e-07 29.3 0.7 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 ORY07079.1 - 9.7e-19 66.0 11.8 6.9e-07 28.5 0.4 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 ORY07079.1 - 1.7e-13 50.2 11.5 3.1e-08 33.3 1.2 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 ORY07079.1 - 6.3e-07 29.3 4.8 0.28 11.2 0.1 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY07079.1 - 3.2e-05 24.2 2.3 0.05 13.9 0.3 3.3 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY07079.1 - 0.00041 20.6 0.4 0.15 12.4 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 ORY07079.1 - 0.015 15.1 1.5 4.5 7.2 0.1 3.5 3 0 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 ORY07079.1 - 0.029 14.7 1.0 14 6.1 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain TAFH PF07531.14 ORY07079.1 - 0.12 12.5 0.0 24 5.1 0.0 2.6 3 0 0 3 3 3 0 NHR1 homology to TAF Caleosin PF05042.13 ORY07079.1 - 0.89 9.5 4.1 48 3.8 0.0 3.5 2 1 1 4 4 4 0 Caleosin related protein zf-CCCH_4 PF18044.1 ORY07080.1 - 1.6e-16 59.6 22.0 1.4e-08 34.4 5.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY07080.1 - 1e-13 50.8 26.9 2.6e-07 30.5 10.6 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY07080.1 - 1.3e-13 50.5 15.9 4.1e-08 32.9 5.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.6 ORY07080.1 - 1.2e-07 31.9 0.0 3.5e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY07080.1 - 4.5e-07 30.4 0.1 1.3e-06 28.9 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY07080.1 - 1.2e-06 28.9 0.1 0.0059 17.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Torus PF16131.5 ORY07080.1 - 2e-06 28.5 8.9 0.0048 17.6 1.5 2.3 1 1 1 2 2 2 2 Torus domain Ank PF00023.30 ORY07080.1 - 2.8e-06 27.5 0.1 1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_2 PF14608.6 ORY07080.1 - 0.00016 22.0 18.4 0.02 15.4 7.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_3 PF13606.6 ORY07080.1 - 0.00026 21.2 0.0 0.0012 19.1 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat zf-CCCH_3 PF15663.5 ORY07080.1 - 0.0007 19.8 3.4 0.0014 18.8 3.4 1.5 1 0 0 1 1 1 1 Zinc-finger containing family Ctr PF04145.15 ORY07081.1 - 0.14 12.8 0.3 0.23 12.1 0.3 1.4 1 1 0 1 1 1 0 Ctr copper transporter family MutS_V PF00488.21 ORY07083.1 - 2.5e-40 138.5 0.2 4.1e-40 137.8 0.1 1.3 2 0 0 2 2 2 1 MutS domain V Pkinase PF00069.25 ORY07084.1 - 2.3e-43 148.5 0.0 1.8e-23 83.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07084.1 - 2.3e-22 79.5 0.0 4.9e-10 39.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY07084.1 - 4.7e-08 32.7 0.0 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY07084.1 - 0.025 14.5 0.0 0.96 9.3 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Tcp11 PF05794.13 ORY07085.1 - 3e-79 267.2 5.8 3.4e-79 267.0 5.8 1.0 1 0 0 1 1 1 1 T-complex protein 11 CENP-U PF13097.6 ORY07085.1 - 0.22 11.4 1.3 0.86 9.5 0.2 2.1 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit G_path_suppress PF15991.5 ORY07086.1 - 0.14 12.3 0.7 0.19 11.8 0.7 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Glyco_transf_49 PF13896.6 ORY07087.1 - 3.2e-41 141.8 0.0 4.2e-37 128.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 ORY07087.1 - 0.036 13.9 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ORY07087.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PCI PF01399.27 ORY07088.1 - 2.2e-07 31.3 0.7 9.6e-07 29.3 0.7 2.1 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 ORY07088.1 - 0.0031 17.4 1.1 0.0075 16.2 1.1 1.7 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Mce4_CUP1 PF11887.8 ORY07088.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative zinc_ribbon_10 PF10058.9 ORY07089.1 - 7.8e-20 70.4 0.9 1.4e-19 69.5 0.9 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DHHC PF01529.20 ORY07089.1 - 1.5 9.0 5.3 0.56 10.3 0.3 2.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase NAD_Gly3P_dh_N PF01210.23 ORY07092.1 - 9.9e-54 181.6 0.1 1.7e-53 180.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY07092.1 - 1.6e-49 167.8 0.1 4.7e-49 166.3 0.2 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORY07092.1 - 0.0093 16.5 0.1 5.3 7.7 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 ORY07093.1 - 2.3e-29 102.4 67.9 7e-22 77.8 34.0 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Wzz PF02706.15 ORY07093.1 - 0.35 11.2 2.1 4.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Chain length determinant protein RGS PF00615.19 ORY07094.1 - 2.8e-13 50.2 0.6 6.2e-13 49.0 0.6 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2304 PF10066.9 ORY07094.1 - 0.44 10.8 4.9 0.57 10.4 4.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Sulfate_transp PF00916.20 ORY07095.1 - 4.7e-90 302.1 14.7 4.7e-90 302.1 14.7 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY07095.1 - 1.5e-19 69.7 0.0 3.1e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY07095.1 - 7.5e-06 26.3 13.7 2.3e-05 24.7 4.7 2.9 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Enkurin PF13864.6 ORY07096.1 - 0.068 13.6 0.3 0.11 13.0 0.3 1.2 1 0 0 1 1 1 0 Calmodulin-binding MOZ_SAS PF01853.18 ORY07097.1 - 1e-76 256.6 0.5 1.5e-76 256.1 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORY07097.1 - 6.7e-23 80.1 4.2 6.7e-23 80.1 4.2 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 ORY07097.1 - 2.9e-14 52.7 1.4 3.2e-14 52.5 0.1 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 ORY07097.1 - 4.9e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY07097.1 - 0.0034 17.6 0.0 0.0078 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Chromo PF00385.24 ORY07097.1 - 0.0036 17.2 0.4 1.6 8.7 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PCEMA1 PF07418.11 ORY07097.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.0 1 1 1 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 Ras PF00071.22 ORY07099.1 - 3.5e-52 176.3 0.1 4.1e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY07099.1 - 2.1e-20 73.1 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY07099.1 - 9.4e-07 28.4 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY07099.1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY07099.1 - 7e-05 22.8 0.3 0.2 11.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY07099.1 - 0.00039 20.0 0.1 0.0024 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORY07099.1 - 0.00059 19.4 0.1 0.0035 16.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_25 PF13481.6 ORY07099.1 - 0.026 14.1 0.0 0.059 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 ORY07099.1 - 0.047 13.7 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY07099.1 - 0.054 13.9 0.1 0.11 12.9 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain HTH_Tnp_Mu_2 PF09039.11 ORY07099.1 - 0.1 12.7 1.3 3.1 7.9 0.2 2.7 2 1 1 3 3 3 0 Mu DNA binding, I gamma subdomain Arrestin_C PF02752.22 ORY07100.1 - 3.1e-12 47.1 0.0 5.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY07100.1 - 0.00052 20.1 0.0 0.0058 16.7 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PLDc_2 PF13091.6 ORY07101.1 - 2.3e-15 56.7 0.0 8e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORY07101.1 - 2.1e-06 27.7 1.0 0.0052 16.9 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif RE_NgoFVII PF09565.10 ORY07101.1 - 0.1 11.9 0.9 1.2 8.4 0.1 2.4 3 0 0 3 3 3 0 NgoFVII restriction endonuclease PAP2 PF01569.21 ORY07102.1 - 4e-28 97.9 2.2 4e-28 97.9 2.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_U4 PF03419.13 ORY07102.1 - 0.96 8.7 8.0 6.7 5.9 0.2 2.4 1 1 1 2 2 2 0 Sporulation factor SpoIIGA PAP2_C PF14360.6 ORY07102.1 - 1.4 9.5 9.5 0.15 12.6 1.1 2.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Arrestin_C PF02752.22 ORY07103.1 - 1e-12 48.6 1.9 4.7e-10 40.1 0.7 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY07103.1 - 3.7e-09 36.8 0.2 8.4e-07 29.1 0.0 3.6 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORY07103.1 - 0.071 12.3 0.6 0.26 10.4 0.2 1.8 2 0 0 2 2 2 0 Rgp1 Arrestin_N PF00339.29 ORY07104.1 - 5.7e-11 42.7 0.0 7.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY07104.1 - 0.00016 21.4 0.0 0.00024 20.9 0.0 1.4 1 1 0 1 1 1 1 Arrestin_N terminal like Arrestin_C PF02752.22 ORY07104.1 - 0.00065 20.2 0.1 0.27 11.7 0.0 2.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Polysacc_lyase PF14099.6 ORY07105.1 - 0.00084 19.3 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase GPI-anchored PF10342.9 ORY07106.1 - 2.9e-15 56.8 0.0 2.9e-15 56.8 0.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1180 PF06679.12 ORY07106.1 - 3.5 8.0 7.1 5.4 7.4 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SOG2 PF10428.9 ORY07106.1 - 9.7 5.3 13.4 12 4.9 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Arrestin_C PF02752.22 ORY07107.1 - 1.9e-09 38.1 1.9 3.8e-09 37.1 0.5 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY07107.1 - 9.2e-07 29.0 0.1 0.011 15.8 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 ORY07109.1 - 3.4e-09 36.9 0.0 8.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 ORY07109.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 ORY07109.1 - 0.00081 19.9 0.9 0.0032 17.9 0.3 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY07109.1 - 0.019 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like PTR2 PF00854.21 ORY07110.1 - 3.1e-78 263.4 9.0 3.1e-78 263.4 9.0 1.7 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 ORY07110.1 - 2e-10 40.1 45.4 2.3e-07 30.1 13.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily LRRC37 PF15779.5 ORY07111.1 - 0.0042 17.4 1.7 0.0069 16.7 1.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeat-containing protein 37 family SOTI PF17079.5 ORY07111.1 - 0.13 12.7 0.1 4.4 7.8 0.1 2.4 2 1 0 2 2 2 0 Male-specific protein scotti Hid1 PF12722.7 ORY07111.1 - 1.9 6.5 3.2 2 6.5 3.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Arrestin_C PF02752.22 ORY07112.1 - 2.6e-19 70.0 0.1 1.3e-17 64.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY07112.1 - 2.2e-13 50.5 0.0 5.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY07112.1 - 0.00033 20.4 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like GILT PF03227.16 ORY07113.1 - 8.7e-17 61.3 1.0 8.7e-17 61.3 1.0 2.0 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Git3 PF11710.8 ORY07115.1 - 1.3e-23 83.8 9.6 2.1e-23 83.2 9.6 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ORY07115.1 - 2.7e-14 53.1 0.3 3.5e-14 52.8 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SANT_DAMP1_like PF16282.5 ORY07116.1 - 4.9e-32 110.0 7.0 1.2e-31 108.7 7.0 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 ORY07116.1 - 6.3e-08 32.7 0.3 6.3e-08 32.7 0.3 2.4 1 1 1 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 ORY07116.1 - 0.032 14.5 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 ORY07117.1 - 4.2e-51 173.8 0.0 5.6e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07117.1 - 3.4e-24 85.5 0.0 4.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY07117.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORY07117.1 - 0.001 19.1 0.2 0.0039 17.2 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cohesin_HEAT PF12765.7 ORY07117.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Spo7 PF03907.13 ORY07120.1 - 0.0078 15.7 2.2 0.0078 15.7 2.2 3.3 2 2 1 3 3 3 1 Spo7-like protein MHYT PF03707.16 ORY07120.1 - 8.2 6.7 8.9 1 9.6 0.1 3.4 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Ribosomal_L31e PF01198.19 ORY07121.1 - 2.7e-39 133.2 2.7 3.4e-39 133.0 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TPT PF03151.16 ORY07123.1 - 6.3e-28 98.0 17.1 7.7e-28 97.7 17.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY07123.1 - 5.1e-09 36.4 30.6 5.4e-05 23.4 6.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY07123.1 - 0.0011 18.2 20.6 0.0016 17.7 20.6 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 ORY07123.1 - 0.0045 16.3 21.8 0.026 13.8 21.8 2.1 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport FUSC PF04632.12 ORY07123.1 - 0.83 8.1 8.4 0.044 12.3 2.9 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family zf-RING_2 PF13639.6 ORY07124.1 - 3e-13 49.9 8.5 6.6e-13 48.8 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY07124.1 - 1.8e-10 40.4 4.9 5.2e-10 38.9 4.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY07124.1 - 2.6e-08 33.6 8.7 4.9e-08 32.7 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY07124.1 - 3.4e-06 26.8 7.3 6.9e-06 25.8 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY07124.1 - 1.2e-05 25.5 10.2 5.8e-05 23.3 10.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY07124.1 - 6.4e-05 22.9 6.2 0.00017 21.5 6.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY07124.1 - 0.0001 22.2 5.2 0.0001 22.2 5.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain PA PF02225.22 ORY07124.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 ORY07124.1 - 0.00028 20.7 4.6 0.00028 20.7 4.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) LRR19-TM PF15176.6 ORY07124.1 - 0.0011 18.9 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain zf-ANAPC11 PF12861.7 ORY07124.1 - 0.0022 18.0 5.0 0.011 15.7 5.1 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4451 PF14616.6 ORY07124.1 - 0.035 14.3 0.3 10 6.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) RINGv PF12906.7 ORY07124.1 - 0.087 13.0 3.2 0.27 11.4 3.2 1.9 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 ORY07124.1 - 0.095 12.9 6.9 1.1 9.5 6.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Di19 PF05605.12 ORY07124.1 - 0.15 12.4 3.0 8.9 6.7 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TadE PF07811.12 ORY07124.1 - 0.16 12.3 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 TadE-like protein zf-Nse PF11789.8 ORY07124.1 - 0.17 11.8 3.3 0.3 10.9 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 ORY07124.1 - 0.25 11.2 9.3 16 5.5 9.8 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY07124.1 - 0.32 10.8 8.1 0.63 9.9 8.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY07124.1 - 0.74 10.0 9.1 1.6 9.0 9.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 ORY07124.1 - 1.1 9.2 5.9 2.3 8.2 5.9 1.6 1 0 0 1 1 1 0 PHD-finger Zip PF02535.22 ORY07126.1 - 8.6e-16 58.1 8.6 1.8e-12 47.2 4.8 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF3147 PF11345.8 ORY07126.1 - 0.0028 18.0 1.3 0.0054 17.1 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3147) DUF1129 PF06570.11 ORY07126.1 - 0.2 11.1 2.0 0.31 10.5 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 7TM-7TMR_HD PF07698.11 ORY07126.1 - 3.2 7.5 14.8 0.22 11.3 9.6 1.7 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Cyt-b5 PF00173.28 ORY07127.1 - 2.1e-25 88.6 0.0 2.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4097 PF13349.6 ORY07128.1 - 2.1e-11 43.7 6.2 1.8e-07 30.8 2.8 2.2 2 0 0 2 2 2 2 Putative adhesin Aminotran_5 PF00266.19 ORY07187.1 - 9.9e-60 202.4 0.0 1.1e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PROCN PF08083.11 ORY07188.1 - 8.6e-236 782.2 8.1 1.4e-235 781.5 8.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 ORY07188.1 - 2.4e-112 374.2 0.1 5e-112 373.2 0.1 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 ORY07188.1 - 3.1e-90 300.2 2.6 8.3e-90 298.8 2.6 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 ORY07188.1 - 4.7e-88 292.9 4.8 1.5e-87 291.2 4.8 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 ORY07188.1 - 2.1e-73 244.7 0.0 4e-73 243.8 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 ORY07188.1 - 3.4e-56 188.5 0.1 8e-56 187.3 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 ORY07188.1 - 7.5e-48 160.8 1.3 1.8e-47 159.6 1.3 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 ORY07188.1 - 2.6e-08 33.8 0.0 5.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DcpS_C PF11969.8 ORY07189.1 - 8e-27 94.0 0.0 1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORY07189.1 - 9.8e-13 48.7 2.0 1.8e-12 47.8 2.0 1.4 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 ORY07189.1 - 0.011 15.6 0.5 0.02 14.8 0.5 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 SKN1 PF03935.15 ORY07190.1 - 1.1e-171 571.7 6.2 2.2e-171 570.7 6.2 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Shisa PF13908.6 ORY07190.1 - 0.003 17.8 0.1 0.0051 17.1 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SKN1 PF03935.15 ORY07191.1 - 6.4e-172 572.4 13.2 6.9e-170 565.7 13.2 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Shisa PF13908.6 ORY07191.1 - 0.0029 17.9 2.0 0.0053 17.0 2.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mucin PF01456.17 ORY07191.1 - 0.011 15.7 9.2 0.019 14.9 9.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PMP1_2 PF08114.11 ORY07191.1 - 0.08 12.7 0.7 0.17 11.7 0.7 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Dicty_REP PF05086.12 ORY07191.1 - 0.094 10.7 0.8 0.12 10.3 0.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.11 ORY07191.1 - 0.23 9.5 4.0 0.32 9.0 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKN1 PF03935.15 ORY07192.1 - 1.3e-167 558.3 7.7 1.6e-167 558.0 7.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HSP70 PF00012.20 ORY07193.1 - 4.3e-244 811.2 10.5 4.8e-244 811.1 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY07193.1 - 2.6e-19 69.2 0.5 3e-18 65.8 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 ORY07193.1 - 0.0067 15.5 0.3 0.063 12.3 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 ORY07193.1 - 0.0092 15.3 0.9 0.02 14.1 0.2 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.11 ORY07193.1 - 0.032 13.5 0.9 0.092 12.0 0.0 2.0 2 1 0 2 2 2 0 StbA protein FtsA PF14450.6 ORY07193.1 - 0.52 10.8 4.8 15 6.1 0.3 3.4 3 1 0 3 3 3 0 Cell division protein FtsA Flagellin_N PF00669.20 ORY07193.1 - 0.73 9.9 9.1 0.13 12.4 4.8 2.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region PCI PF01399.27 ORY07194.1 - 1.9e-08 34.8 0.0 5.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain ETF PF01012.21 ORY07195.1 - 2.1e-48 164.6 4.2 2.7e-48 164.3 4.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain MvaI_BcnI PF15515.6 ORY07195.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family PPR_2 PF13041.6 ORY07196.1 - 1.6e-36 124.2 9.3 1e-12 48.0 0.0 10.5 10 2 3 13 13 13 6 PPR repeat family PPR_3 PF13812.6 ORY07196.1 - 1.3e-31 108.4 4.9 2.5e-09 37.1 0.0 7.5 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 ORY07196.1 - 2.2e-19 68.3 14.2 0.00017 21.6 0.0 11.3 12 0 0 12 12 12 4 PPR repeat PPR_long PF17177.4 ORY07196.1 - 3.8e-17 62.4 8.3 0.0011 18.4 0.0 6.3 4 2 1 6 6 6 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY07196.1 - 6.6e-16 57.7 4.9 0.00071 19.2 0.0 7.6 7 0 0 7 7 7 3 PPR repeat TPR_12 PF13424.6 ORY07196.1 - 6.2e-05 23.2 0.1 8.1 6.8 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat FF PF01846.19 ORY07196.1 - 0.0001 22.4 0.4 0.54 10.5 0.1 4.0 3 0 0 3 3 3 2 FF domain TPR_14 PF13428.6 ORY07196.1 - 0.00051 20.6 0.0 23 6.1 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY07196.1 - 0.0013 19.2 1.1 2.3 8.8 0.0 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat ATP13 PF12921.7 ORY07196.1 - 0.0016 18.2 1.1 10 6.0 0.4 4.9 3 1 1 4 4 4 1 Mitochondrial ATPase expression TPR_1 PF00515.28 ORY07196.1 - 0.0027 17.4 1.4 9.7 6.2 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY07196.1 - 0.0097 16.1 0.3 8.1 6.7 0.1 4.7 3 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ORY07196.1 - 0.041 14.0 4.5 12 6.3 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat CLTH PF10607.9 ORY07196.1 - 0.069 13.0 4.0 0.36 10.7 1.3 3.4 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Clathrin PF00637.20 ORY07196.1 - 1.8 8.5 9.7 21 5.0 0.1 5.1 4 1 2 6 6 6 0 Region in Clathrin and VPS Ribosomal_L12 PF00542.19 ORY07197.1 - 4.5e-23 81.4 10.6 1.4e-21 76.6 5.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ORY07197.1 - 6e-17 61.1 4.9 6e-17 61.1 4.9 2.5 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain CryBP1 PF07029.11 ORY07197.1 - 0.11 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 CryBP1 protein Ribosomal_60s PF00428.19 ORY07197.1 - 4.1 8.1 15.4 0.14 12.8 7.2 2.5 2 1 1 3 3 3 0 60s Acidic ribosomal protein Not3 PF04065.15 ORY07198.1 - 1.3e-87 293.1 29.9 2.6e-87 292.1 29.9 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ORY07198.1 - 8.9e-46 155.2 11.8 8.9e-46 155.2 11.8 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 ORY07198.1 - 0.018 15.4 6.0 0.018 15.4 6.0 2.3 2 1 0 2 2 2 0 Syntaxin-like protein DUF19 PF01579.18 ORY07198.1 - 1 9.1 7.4 2.1 8.1 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF19) DHO_dh PF01180.21 ORY07198.1 - 1.1 8.4 4.3 0.51 9.5 1.2 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Cep57_MT_bd PF06657.13 ORY07198.1 - 1.6 9.3 10.2 0.12 12.8 2.7 2.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1957 PF09210.11 ORY07198.1 - 4.1 7.9 8.2 0.98 9.9 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1957) Ribosomal_S26e PF01283.19 ORY07199.1 - 1.7e-54 182.8 6.4 2e-54 182.6 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 ORY07199.1 - 0.071 13.7 2.6 0.8 10.3 1.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 ORY07200.1 - 4.8e-14 51.5 17.5 1.7e-08 33.9 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ORY07200.1 - 7e-13 48.9 10.4 1.1e-12 48.3 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ORY07200.1 - 1.2e-10 42.1 6.6 2.7e-05 25.0 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ORY07200.1 - 1.1e-09 38.2 4.4 0.00025 21.1 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ORY07200.1 - 1e-08 35.2 10.2 1.6e-08 34.5 10.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY07200.1 - 2.4e-08 34.0 21.7 5.2e-06 26.5 12.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ORY07200.1 - 3.9e-07 29.8 17.8 0.00038 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 ORY07200.1 - 9e-07 29.3 19.3 0.00049 20.5 12.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ORY07200.1 - 1.4e-06 28.1 12.1 0.0027 17.7 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ORY07200.1 - 1.3e-05 25.3 12.0 0.00049 20.4 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ORY07200.1 - 0.00086 19.8 12.0 0.057 14.0 12.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 ORY07200.1 - 0.014 15.6 6.3 0.32 11.3 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 ORY07200.1 - 0.014 15.9 14.6 0.64 10.6 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 ORY07200.1 - 0.054 13.7 8.9 1.4 9.2 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 ORY07200.1 - 0.2 12.7 16.3 0.34 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 ORY07200.1 - 0.29 11.3 6.1 2 8.6 1.1 2.4 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 ORY07200.1 - 0.73 10.7 11.7 2.5 9.0 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain cNMP_binding PF00027.29 ORY07201.1 - 1.4e-43 146.9 0.0 6.6e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ORY07201.1 - 3e-09 36.4 0.5 5.6e-09 35.5 0.5 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_3 PF05899.12 ORY07201.1 - 0.11 12.3 0.2 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF2812 PF11193.8 ORY07201.1 - 0.13 12.5 0.6 0.32 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Actin PF00022.19 ORY07202.1 - 6.9e-134 446.5 0.0 2.7e-133 444.5 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY07202.1 - 0.0013 17.7 0.0 0.014 14.3 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Ribosomal_L28e PF01778.17 ORY07203.1 - 1.6e-41 141.7 1.4 1.6e-41 141.7 1.4 2.1 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 ORY07203.1 - 9.3e-28 96.8 16.7 9.3e-28 96.8 16.7 2.6 3 1 0 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 ORY07203.1 - 0.008 15.6 19.9 0.01 15.2 19.9 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 ORY07203.1 - 0.048 13.4 2.2 0.078 12.7 2.2 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain LTV PF04180.14 ORY07203.1 - 0.072 12.8 18.4 0.093 12.4 18.4 1.1 1 0 0 1 1 1 0 Low temperature viability protein CDC45 PF02724.14 ORY07203.1 - 4.1 5.6 18.5 6 5.0 18.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2462 PF09495.10 ORY07203.1 - 7.7 7.3 12.2 2 9.2 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Na_Ca_ex PF01699.24 ORY07204.1 - 5.7e-18 65.3 18.1 1e-16 61.3 4.3 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein CBFD_NFYB_HMF PF00808.23 ORY07205.1 - 3.1e-28 97.9 0.6 4.5e-28 97.3 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY07205.1 - 2.9e-06 27.7 0.1 4.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY07205.1 - 0.0028 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 ORY07205.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-X PF09415.10 ORY07205.1 - 0.044 14.1 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TFIID-18kDa PF02269.16 ORY07205.1 - 0.045 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit HMG-CoA_red PF00368.18 ORY07206.1 - 4.3e-147 489.9 1.5 6.3e-147 489.4 1.1 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 ORY07206.1 - 7.7e-15 55.0 10.8 2.5e-14 53.4 10.8 1.9 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORY07206.1 - 5.6e-08 31.4 11.3 1e-07 30.5 8.2 2.1 1 1 1 2 2 2 1 Patched family HPIH PF13323.6 ORY07206.1 - 0.062 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain with HPIH motif bZIP_1 PF00170.21 ORY07207.1 - 7e-05 22.9 13.1 0.0029 17.7 11.0 3.0 2 1 0 2 2 2 1 bZIP transcription factor Miff PF05644.11 ORY07207.1 - 0.00038 20.2 0.5 0.00059 19.6 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff bZIP_2 PF07716.15 ORY07207.1 - 0.0017 18.4 3.6 0.41 10.8 0.1 2.4 2 0 0 2 2 2 2 Basic region leucine zipper ZapB PF06005.12 ORY07207.1 - 0.013 16.0 0.8 0.028 14.9 0.8 1.6 1 0 0 1 1 1 0 Cell division protein ZapB IFP_35_N PF07334.13 ORY07207.1 - 0.057 13.5 0.2 0.21 11.7 0.2 2.0 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PAP1 PF08601.10 ORY07207.1 - 0.078 12.7 1.4 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 DUF465 PF04325.13 ORY07207.1 - 0.17 12.0 2.1 0.36 10.9 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) UPF0242 PF06785.11 ORY07207.1 - 0.28 11.3 6.2 3.9 7.5 0.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 ORY07207.1 - 0.32 11.5 1.7 1.1 9.7 1.3 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) His_Phos_1 PF00300.22 ORY07208.1 - 7.6e-26 91.0 0.0 9.2e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) cNMP_binding PF00027.29 ORY07209.1 - 1.7e-41 140.2 0.1 5e-21 74.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain G-patch PF01585.23 ORY07209.1 - 5.4e-16 58.2 1.1 9.8e-16 57.4 1.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY07209.1 - 1.8e-07 31.1 0.2 8e-07 29.1 0.2 2.2 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 ORY07209.1 - 0.0038 16.8 3.0 0.0038 16.8 3.0 2.3 2 0 0 2 2 2 1 RED-like protein N-terminal region RRM_1 PF00076.22 ORY07210.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transketolase_N PF00456.21 ORY07211.1 - 7.8e-153 508.3 0.0 1e-152 507.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY07211.1 - 5.2e-44 150.0 0.0 1.1e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY07211.1 - 4.8e-14 52.3 0.0 1.8e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY07211.1 - 3.5e-06 26.4 0.0 0.00019 20.7 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase YqzH PF14164.6 ORY07211.1 - 0.061 13.4 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 YqzH-like protein Fungal_trans PF04082.18 ORY07212.1 - 9.9e-36 123.1 0.6 2.5e-35 121.8 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07212.1 - 1.9e-13 50.3 10.6 3.6e-13 49.4 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.12 ORY07213.1 - 2.4e-15 56.4 7.8 6.7e-15 55.0 7.8 1.8 1 0 0 1 1 1 1 cwf21 domain Ala_racemase_N PF01168.20 ORY07214.1 - 3.4e-28 98.8 0.0 4.2e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.16 ORY07214.1 - 0.0069 15.3 0.5 0.011 14.6 0.1 1.5 2 0 0 2 2 2 1 3-dehydroquinate synthase II Importin_rep_6 PF18829.1 ORY07214.1 - 0.04 14.1 0.1 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Importin repeat 6 AIRS_C PF02769.22 ORY07215.1 - 3.9e-14 53.1 0.1 6.4e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain RST PF12174.8 ORY07215.1 - 0.00027 20.8 0.0 0.00067 19.5 0.0 1.6 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain Zip PF02535.22 ORY07216.1 - 2e-49 168.6 12.6 1.5e-48 165.7 12.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Phosphorylase PF00343.20 ORY07217.1 - 0 1073.6 0.0 0 1073.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase HA70_C PF17993.1 ORY07217.1 - 0.067 13.2 0.1 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Haemagglutinin 70 C-terminal domain Sigma_reg_C PF13791.6 ORY07217.1 - 0.081 13.1 0.3 0.17 12.1 0.3 1.5 1 0 0 1 1 1 0 Sigma factor regulator C-terminal CTK3_C PF12350.8 ORY07217.1 - 0.7 10.1 6.1 3 8.1 1.1 3.0 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 C-terminus OCD_Mu_crystall PF02423.15 ORY07218.1 - 0.0074 15.3 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Choline_kinase PF01633.20 ORY07219.1 - 5.9e-22 78.3 0.2 4.8e-21 75.3 0.0 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY07219.1 - 3.2e-07 30.5 0.0 4.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY07219.1 - 0.0055 15.5 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cyt-b5 PF00173.28 ORY07221.1 - 2.8e-25 88.3 0.0 3e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_2 PF00890.24 ORY07222.1 - 4.6e-78 263.1 0.1 5.5e-78 262.9 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY07222.1 - 4.7e-15 56.0 0.1 8.4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY07222.1 - 1.1e-08 34.9 0.8 2.6e-08 33.7 0.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY07222.1 - 1.1e-08 34.7 0.5 2.4e-07 30.3 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY07222.1 - 2.4e-08 34.1 0.8 1.9e-07 31.2 0.3 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY07222.1 - 8.9e-07 27.9 2.4 0.0005 18.9 0.3 3.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY07222.1 - 6.9e-06 25.5 0.1 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY07222.1 - 4.7e-05 22.8 0.1 6.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY07222.1 - 4.8e-05 22.7 0.7 0.003 16.8 0.3 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 ORY07222.1 - 0.0006 20.3 1.1 0.042 14.4 0.5 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY07222.1 - 0.0053 16.1 0.3 0.01 15.1 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY07222.1 - 0.0054 15.9 3.7 0.0057 15.8 0.2 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A IF2_N PF04760.15 ORY07222.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NAD_binding_9 PF13454.6 ORY07222.1 - 0.048 13.6 0.4 0.51 10.3 0.4 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ORY07222.1 - 0.061 13.8 0.2 0.18 12.2 0.1 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORY07222.1 - 0.073 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 ORY07222.1 - 0.13 11.6 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Herpes_BLRF2 PF05812.12 ORY07222.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein 3HCDH_N PF02737.18 ORY07222.1 - 0.17 11.7 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 ORY07222.1 - 0.21 10.7 0.4 7.5 5.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FUSC_2 PF13515.6 ORY07223.1 - 3.1e-18 66.1 22.9 2.3e-17 63.3 9.7 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY07223.1 - 3.4e-12 46.7 0.0 6.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ORY07223.1 - 3.7e-09 35.7 1.7 8.1e-09 34.6 1.7 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 ORY07223.1 - 1.5e-05 24.0 7.7 1.5e-05 24.0 7.7 2.4 2 1 1 3 3 3 1 Aluminium activated malate transporter PS_pyruv_trans PF04230.13 ORY07223.1 - 0.092 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase ArAE_1 PF06081.11 ORY07223.1 - 1.5 8.9 9.1 0.85 9.8 5.9 2.3 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 FAR1 PF03101.15 ORY07224.1 - 7.9e-07 29.7 4.0 1.5e-06 28.8 4.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Herpes_DNAp_acc PF04929.12 ORY07225.1 - 0.017 14.1 1.4 0.019 13.9 1.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor WD40 PF00400.32 ORY07226.1 - 6.7e-11 42.6 4.4 0.13 13.2 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07226.1 - 0.0002 21.6 0.0 0.3 11.4 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 ORY07226.1 - 0.0054 16.4 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 CNH domain PX PF00787.24 ORY07227.1 - 9.2e-25 86.8 0.7 9.2e-25 86.8 0.7 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY07227.1 - 2.4e-23 82.9 14.5 7.3e-16 58.4 3.0 2.2 1 1 1 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 ORY07227.1 - 0.00014 21.6 15.1 0.0041 16.8 7.3 2.9 1 1 1 2 2 2 1 BAR domain of APPL family HAUS-augmin3 PF14932.6 ORY07227.1 - 0.0006 19.5 0.4 0.0006 19.5 0.4 2.7 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Sec34 PF04136.15 ORY07227.1 - 0.00065 19.6 1.1 0.00065 19.6 1.1 2.6 2 1 0 2 2 2 1 Sec34-like family APG6_N PF17675.1 ORY07227.1 - 0.016 15.7 3.1 0.016 15.7 3.1 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF4164 PF13747.6 ORY07227.1 - 0.019 15.2 2.2 0.72 10.2 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 ORY07227.1 - 0.056 13.5 2.9 0.97 9.5 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II DASH_Dam1 PF08653.10 ORY07227.1 - 0.2 11.5 1.0 1 9.2 0.2 2.7 2 1 1 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 ORY07227.1 - 0.47 10.9 5.5 2.5 8.7 0.2 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 ORY07227.1 - 0.91 9.9 13.2 16 5.9 0.8 4.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPO PF05929.11 ORY07227.1 - 2.5 7.6 10.3 0.29 10.7 0.3 2.3 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase RhoGEF PF00621.20 ORY07227.1 - 3.9 7.7 13.5 0.35 11.1 6.3 2.7 1 1 2 3 3 3 0 RhoGEF domain Syntaxin_2 PF14523.6 ORY07227.1 - 4 7.9 13.1 16 6.0 5.6 3.4 1 1 0 2 2 2 0 Syntaxin-like protein Vac_Fusion PF02346.16 ORY07227.1 - 4.7 6.9 6.2 2 8.1 0.3 3.2 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Fib_alpha PF08702.10 ORY07227.1 - 4.9 7.3 11.4 5.7 7.1 0.4 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY07227.1 - 6.4 7.1 6.7 21 5.4 0.6 2.9 2 0 0 2 2 2 0 Haemolysin XhlA P4Ha_N PF08336.11 ORY07227.1 - 7 6.7 9.9 6.1 6.9 0.3 3.4 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF16 PF01519.16 ORY07227.1 - 8.9 6.9 16.4 0.33 11.4 0.6 3.1 3 1 0 3 3 2 0 Protein of unknown function DUF16 RNA_pol_Rpb6 PF01192.22 ORY07228.1 - 7.6e-16 57.8 0.1 9.4e-16 57.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ribosomal_S21e PF01249.18 ORY07229.1 - 3.2e-40 136.1 0.0 3.6e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4325 PF14213.6 ORY07229.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) COX7C PF02935.16 ORY07230.1 - 7.5e-18 64.6 0.4 7.9e-18 64.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc HSF_DNA-bind PF00447.17 ORY07231.1 - 1.6e-23 83.1 0.1 2.2e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Oxidored_molyb PF00174.19 ORY07232.1 - 2.6e-52 176.9 0.0 4e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY07232.1 - 2e-39 134.8 0.1 3.8e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 ORY07232.1 - 1.8e-34 118.0 0.0 3.2e-33 114.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY07232.1 - 7.6e-32 110.2 0.0 1.5e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORY07232.1 - 1.6e-22 79.4 0.0 4.1e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORY07232.1 - 1.4e-07 31.8 0.0 5.5e-07 29.8 0.0 1.9 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ORY07232.1 - 0.027 14.7 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ribosom_S12_S23 PF00164.25 ORY07233.1 - 5.4e-52 174.2 0.7 6.8e-52 173.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Forkhead PF00250.18 ORY07234.1 - 5.8e-32 109.8 0.9 6.3e-32 109.7 0.9 1.0 1 0 0 1 1 1 1 Forkhead domain START PF01852.19 ORY07235.1 - 8.1e-22 77.7 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.20 ORY07235.1 - 0.06 13.5 0.4 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport BOFC_N PF08977.10 ORY07237.1 - 0.063 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal RNase_PH PF01138.21 ORY07238.1 - 7.1e-38 130.1 0.0 1.1e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY07238.1 - 5.7e-08 32.7 0.2 1.4e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycoprotein_B PF00606.18 ORY07238.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain NMD3 PF04981.13 ORY07239.1 - 1.2e-80 270.5 7.5 1.7e-80 270.0 7.5 1.2 1 0 0 1 1 1 1 NMD3 family Oxidored_q6 PF01058.22 ORY07240.1 - 6.9e-23 80.9 0.3 1e-22 80.4 0.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit p450 PF00067.22 ORY07241.1 - 4.4e-84 282.9 0.2 5.1e-84 282.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helicase_C PF00271.31 ORY07243.1 - 2.1e-20 73.1 0.1 6.6e-20 71.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY07243.1 - 1.1e-18 67.9 0.0 4.7e-18 65.8 0.0 2.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY07243.1 - 9.8e-17 61.3 0.0 6.2e-14 52.1 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 ORY07243.1 - 0.00073 18.8 0.0 0.0018 17.5 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Use1 PF09753.9 ORY07243.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 SWI2_SNF2 PF18766.1 ORY07243.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 ORY07243.1 - 0.077 13.3 0.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP1_OBG PF01018.22 ORY07245.1 - 8.2e-46 155.4 3.3 8.2e-44 148.9 3.3 2.2 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 ORY07245.1 - 1.5e-23 83.0 0.0 3.8e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY07245.1 - 4.3e-09 36.1 0.0 9.7e-09 34.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 ORY07245.1 - 1.5e-06 27.8 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY07245.1 - 1.7e-05 24.3 0.0 4.2e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_C PF08438.10 ORY07245.1 - 0.00018 22.0 0.3 0.00062 20.3 0.4 1.9 2 0 0 2 2 2 1 GTPase of unknown function C-terminal Dynamin_N PF00350.23 ORY07245.1 - 0.017 15.2 0.2 2.9 7.9 0.1 3.5 2 1 0 2 2 2 0 Dynamin family PUFD PF16553.5 ORY07245.1 - 0.066 13.3 0.1 0.23 11.6 0.1 1.9 1 1 1 2 2 2 0 BCORL-PCGF1-binding domain AAA_21 PF13304.6 ORY07245.1 - 0.098 12.4 0.4 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF727 PF05303.12 ORY07246.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) p450 PF00067.22 ORY07247.1 - 5.7e-95 318.8 0.0 8.1e-95 318.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY07247.1 - 2.4e-32 112.3 0.0 4.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY07247.1 - 1.7e-22 80.2 0.0 4.7e-22 78.7 0.0 1.9 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY07247.1 - 3.6e-15 56.5 0.1 3.8e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cg6151-P PF10233.9 ORY07248.1 - 6.6e-21 74.7 11.8 7.8e-21 74.5 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PTPS_related PF10131.9 ORY07248.1 - 0.35 9.1 7.4 0.38 9.0 7.4 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Vma12 PF11712.8 ORY07248.1 - 3.7 7.6 5.8 9.4 6.3 0.2 2.3 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SH PF01445.17 ORY07248.1 - 5.5 7.0 9.0 0.78 9.8 0.9 2.2 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF373 PF04123.13 ORY07248.1 - 6.2 6.2 9.9 47 3.3 10.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DJ-1_PfpI PF01965.24 ORY07311.1 - 9e-09 35.3 0.0 1.8e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY07311.1 - 0.00028 20.6 0.0 0.00097 18.9 0.0 1.8 2 0 0 2 2 2 1 ThiJ/PfpI family-like Latrotoxin_C PF15658.6 ORY07311.1 - 0.0043 16.8 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Latrotoxin C-terminal domain Na_H_Exchanger PF00999.21 ORY07313.1 - 6.1e-36 124.0 50.1 6.8e-21 74.5 25.7 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family MFS_1 PF07690.16 ORY07314.1 - 4.8e-30 104.7 18.9 7e-30 104.1 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ca_hom_mod PF14798.6 ORY07314.1 - 0.016 14.4 0.1 0.077 12.1 0.0 2.0 2 0 0 2 2 2 0 Calcium homeostasis modulator Symplekin_C PF12295.8 ORY07315.1 - 1.5e-64 217.6 1.1 2.9e-63 213.3 0.3 2.8 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 ORY07315.1 - 2.5e-51 174.5 0.4 2.5e-51 174.5 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) ADP_PFK_GK PF04587.15 ORY07315.1 - 0.033 12.8 0.0 0.065 11.8 0.0 1.4 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region RNA_pol_Rpc82 PF05645.13 ORY07316.1 - 4.7e-27 95.4 9.7 2.8e-26 92.8 4.8 2.8 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 ORY07316.1 - 1.1e-19 70.2 2.4 3.9e-15 55.7 0.7 3.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 ORY07316.1 - 1.3e-06 28.2 8.5 0.0081 16.0 0.1 5.3 4 1 1 5 5 5 2 TFIIE alpha subunit FlgM PF04316.13 ORY07316.1 - 0.0046 17.3 1.4 5.3 7.5 0.0 3.1 2 0 0 2 2 2 2 Anti-sigma-28 factor, FlgM TrmB PF01978.19 ORY07316.1 - 0.014 15.2 2.7 0.27 11.1 0.1 3.5 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DEAD PF00270.29 ORY07316.1 - 0.16 11.7 1.7 1.6 8.5 1.7 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase RRM_1 PF00076.22 ORY07317.1 - 4e-05 23.3 0.0 7.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 ORY07317.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 GAGA_bind PF06217.12 ORY07317.1 - 1.1 9.4 11.4 0.48 10.7 4.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Pannexin_like PF12534.8 ORY07317.1 - 3.4 6.7 5.2 0.82 8.7 1.5 1.7 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 CENP-N PF05238.13 ORY07317.1 - 8 5.6 9.4 1.5 8.0 3.0 2.0 2 0 0 2 2 2 0 Kinetochore protein CHL4 like WD40 PF00400.32 ORY07318.1 - 3.5e-31 106.7 13.2 2.5e-07 31.3 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07318.1 - 2.4e-27 95.1 0.3 2.5e-05 24.5 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY07318.1 - 8.2e-15 55.2 0.2 3.6e-06 27.0 0.0 3.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORY07318.1 - 5e-06 25.3 0.0 0.0076 14.8 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 ORY07318.1 - 2e-05 24.4 0.1 0.00078 19.3 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 ORY07318.1 - 6.6e-05 22.1 0.2 0.024 13.7 0.1 2.4 2 1 0 3 3 3 2 Coatomer WD associated region Peptidase_S9_N PF02897.15 ORY07318.1 - 0.011 14.5 1.8 1.3 7.8 0.1 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 ORY07318.1 - 0.013 14.1 0.7 0.032 12.9 0.2 1.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY07318.1 - 0.019 14.3 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain IKI3 PF04762.12 ORY07318.1 - 0.03 12.4 1.0 0.21 9.5 1.0 2.2 1 1 0 1 1 1 0 IKI3 family DPPIV_N PF00930.21 ORY07318.1 - 0.047 12.4 0.1 0.29 9.8 0.0 2.2 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region BOP1NT PF08145.12 ORY07319.1 - 4.5e-115 384.0 13.0 4.5e-115 384.0 13.0 1.7 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 ORY07319.1 - 1.4e-26 92.2 6.5 9e-09 35.8 0.2 7.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07319.1 - 5.2e-08 33.1 0.1 0.074 13.4 0.1 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 ORY07319.1 - 0.059 12.8 19.6 0.12 11.8 19.6 1.5 1 0 0 1 1 1 0 SDA1 DUF1289 PF06945.13 ORY07319.1 - 0.064 13.1 0.5 5.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Gmad1 PF10647.9 ORY07319.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain SHS2_Rpb7-N PF03876.17 ORY07320.1 - 6.2e-16 58.5 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORY07320.1 - 6.3e-13 48.9 0.0 9.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 ORY07320.1 - 0.02 15.1 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DNA_pol_A_exo1 PF01612.20 ORY07321.1 - 1.2e-48 165.1 1.0 1.8e-48 164.5 1.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 ORY07321.1 - 2.7e-24 85.7 1.0 5.9e-23 81.4 0.8 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 ORY07321.1 - 8.7e-14 51.3 0.0 1.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Intimin_C PF07979.11 ORY07321.1 - 0.015 15.7 0.2 0.043 14.2 0.2 1.7 1 0 0 1 1 1 0 Intimin C-type lectin domain LMSTEN PF07988.12 ORY07321.1 - 0.054 13.0 0.2 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 LMSTEN motif Arm PF00514.23 ORY07322.1 - 1.6e-24 85.1 1.3 2.3e-05 24.3 0.1 7.3 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY07322.1 - 2.1e-11 44.0 0.0 9.2e-05 22.8 0.0 4.0 2 1 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 ORY07322.1 - 2.4e-11 43.9 0.2 0.00037 20.9 0.0 4.1 3 1 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 ORY07322.1 - 3.8e-06 26.7 0.4 1.3 9.5 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat RICTOR_V PF14668.6 ORY07322.1 - 0.0004 20.6 0.0 1.1 9.5 0.0 3.5 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 ORY07322.1 - 0.0044 17.1 0.0 1.5 9.0 0.0 3.2 3 1 1 4 4 4 1 V-ATPase subunit H RVP_2 PF08284.11 ORY07323.1 - 0.034 13.9 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4257 PF14074.6 ORY07323.1 - 0.097 12.9 1.9 18 5.6 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4257) CENP-I PF07778.11 ORY07324.1 - 5.3e-56 190.4 4.0 7.7e-36 123.9 0.0 2.1 1 1 1 2 2 2 2 Mis6 Pox_P4B PF03292.14 ORY07326.1 - 0.051 11.8 0.0 0.055 11.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein EF-hand_1 PF00036.32 ORY07328.1 - 1.1e-16 59.1 0.0 1.3e-07 30.7 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 ORY07328.1 - 7.7e-16 58.3 0.1 4.8e-11 42.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY07328.1 - 1e-15 56.2 0.2 1.3e-07 30.9 0.0 4.3 4 2 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 ORY07328.1 - 1.5e-14 53.6 0.5 1.2e-09 37.9 0.0 4.0 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY07328.1 - 1.9e-07 30.3 0.7 7.3e-06 25.2 0.0 2.8 2 1 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 ORY07328.1 - 2.2e-07 31.1 0.0 0.0037 17.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 ORY07328.1 - 0.00072 19.6 0.0 0.0027 17.8 0.0 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 ORY07328.1 - 0.022 14.8 0.0 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 ORY07328.1 - 0.05 14.5 0.0 0.074 13.9 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain DUF5644 PF18712.1 ORY07328.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5644) Glyco_transf_34 PF05637.12 ORY07329.1 - 4.1e-37 128.2 5.3 2.3e-34 119.2 5.3 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY07329.1 - 0.001 19.1 0.6 0.0014 18.6 0.6 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 ORY07329.1 - 0.0036 16.9 0.7 0.0097 15.5 0.3 1.7 1 1 1 2 2 2 1 Protein of unknown function, DUF273 DUF309 PF03745.14 ORY07329.1 - 0.029 14.1 0.7 0.2 11.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF309) DUF2653 PF10850.8 ORY07329.1 - 0.11 12.7 0.5 0.66 10.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2653) DUF2009 PF09418.10 ORY07331.1 - 5e-211 701.6 0.0 5.9e-211 701.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 ORY07331.1 - 0.0011 19.1 4.6 0.0026 17.9 4.6 1.6 1 0 0 1 1 1 1 B-box zinc finger zf-CRD PF17979.1 ORY07331.1 - 0.013 15.6 0.5 0.03 14.4 0.5 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions CEBP_ZZ PF16366.5 ORY07331.1 - 1.9 8.8 6.4 1.6 9.0 3.0 2.2 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain COPIIcoated_ERV PF07970.12 ORY07332.1 - 5.2e-84 281.5 2.3 6.8e-84 281.1 2.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY07332.1 - 5.5e-28 97.1 0.0 1e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pre-PUA PF17832.1 ORY07333.1 - 3e-28 98.3 0.4 4.5e-28 97.8 0.4 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 ORY07333.1 - 2e-17 62.9 0.0 2.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 PUA domain RPA_interact_C PF14768.6 ORY07334.1 - 5.1e-14 52.6 8.7 5.1e-14 52.6 8.7 1.8 2 0 0 2 2 2 1 Replication protein A interacting C-terminal Acetyltransf_1 PF00583.25 ORY07335.1 - 7.2e-10 39.1 0.0 9.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY07335.1 - 5.9e-06 26.2 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY07335.1 - 0.00019 21.8 0.0 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3512 PF12024.8 ORY07336.1 - 0.00013 21.5 0.2 0.00032 20.3 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) bPH_3 PF14470.6 ORY07337.1 - 0.089 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Vps36_ESCRT-II PF11605.8 ORY07337.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 CsbD PF05532.12 ORY07338.1 - 2e-37 126.8 18.3 5.5e-10 39.0 0.3 4.1 3 1 1 4 4 4 4 CsbD-like CsbD PF05532.12 ORY07339.1 - 7.8e-38 128.2 17.0 8.5e-10 38.4 0.2 4.1 3 1 1 4 4 4 4 CsbD-like CsbD PF05532.12 ORY07340.1 - 1.5e-34 117.6 21.3 7.7e-10 38.5 0.3 4.2 3 1 1 4 4 4 4 CsbD-like CsbD PF05532.12 ORY07341.1 - 1e-30 105.4 5.1 3.5e-08 33.2 0.4 4.1 3 1 1 4 4 4 4 CsbD-like DUF3813 PF12758.7 ORY07341.1 - 2 8.8 6.0 22 5.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) EGF_MSP1_1 PF12946.7 ORY07342.1 - 0.037 14.1 1.7 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 Zip PF02535.22 ORY07342.1 - 0.14 11.4 3.3 0.13 11.4 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 ORY07342.1 - 0.57 9.5 5.7 0.63 9.3 5.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein CsbD PF05532.12 ORY07343.1 - 1.8e-37 127.0 16.1 1.4e-08 34.5 0.2 4.1 3 1 1 4 4 4 4 CsbD-like CsbD PF05532.12 ORY07344.1 - 1.7e-29 101.5 15.8 4.2e-10 39.4 0.2 3.1 2 1 1 3 3 3 3 CsbD-like EGF_MSP1_1 PF12946.7 ORY07345.1 - 0.037 14.1 1.7 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 Zip PF02535.22 ORY07345.1 - 0.14 11.4 3.3 0.13 11.4 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 ORY07345.1 - 0.57 9.5 5.7 0.63 9.3 5.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein EGF_MSP1_1 PF12946.7 ORY07346.1 - 0.037 14.1 1.7 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 Zip PF02535.22 ORY07346.1 - 0.14 11.4 3.3 0.13 11.4 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 ORY07346.1 - 0.57 9.5 5.7 0.63 9.3 5.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein CsbD PF05532.12 ORY07347.1 - 8e-20 70.5 1.7 4.3e-09 36.1 0.4 2.0 2 0 0 2 2 2 2 CsbD-like Dapper PF15268.6 ORY07348.1 - 0.021 13.7 11.0 0.022 13.7 11.0 1.0 1 0 0 1 1 1 0 Dapper Macoilin PF09726.9 ORY07348.1 - 0.027 13.1 18.9 0.032 12.8 18.9 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 ORY07348.1 - 0.61 8.8 13.0 0.8 8.4 13.0 1.2 1 0 0 1 1 1 0 Presenilin CsbD PF05532.12 ORY07349.1 - 5.3e-37 125.5 16.6 1.4e-08 34.5 0.2 4.1 3 1 1 4 4 4 4 CsbD-like CsbD PF05532.12 ORY07350.1 - 5.2e-20 71.1 8.3 2.2e-09 37.1 0.3 2.1 1 1 1 2 2 2 2 CsbD-like AMMECR1 PF01871.17 ORY07351.1 - 7.4e-49 165.6 0.0 8.6e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Tyrosinase PF00264.20 ORY07352.1 - 5.7e-26 92.2 6.0 2.5e-24 86.8 6.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase zf-C3HC PF07967.13 ORY07353.1 - 2.4e-27 95.6 2.8 1.4e-21 76.9 0.2 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 ORY07353.1 - 1.2e-16 60.6 9.5 1.1e-14 54.4 2.6 3.0 2 1 0 2 2 2 2 Rsm1-like MRI PF15325.6 ORY07353.1 - 7.8 7.7 6.3 1.7 9.8 0.2 2.5 3 0 0 3 3 3 0 Modulator of retrovirus infection E1-E2_ATPase PF00122.20 ORY07354.1 - 2.8e-22 79.1 0.0 7.5e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY07354.1 - 2.5e-18 67.2 0.0 7.3e-11 42.8 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY07354.1 - 1.7e-05 24.8 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY07354.1 - 0.014 15.1 0.3 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Septin PF00735.18 ORY07355.1 - 5.3e-120 399.9 0.1 5.3e-120 399.9 0.1 2.0 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY07355.1 - 8.4e-09 35.5 0.3 3.5e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY07355.1 - 3e-05 24.0 9.1 0.0005 20.0 0.5 3.6 3 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ORY07355.1 - 0.00062 19.3 8.5 0.0014 18.2 0.0 3.4 2 2 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 ORY07355.1 - 0.00064 20.3 9.7 1.8 9.0 10.5 2.2 2 0 0 2 2 2 2 AAA domain Ras PF00071.22 ORY07355.1 - 0.0017 18.0 0.2 0.0079 15.8 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 ORY07355.1 - 0.0019 18.4 0.0 0.0097 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 ORY07355.1 - 0.0026 17.1 4.1 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 ORY07355.1 - 0.0042 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY07355.1 - 0.006 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY07355.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3958 PF13125.6 ORY07355.1 - 0.016 15.4 15.2 0.037 14.2 15.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) ABC_tran PF00005.27 ORY07355.1 - 0.026 15.0 10.6 7.3 7.1 10.6 2.7 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 ORY07355.1 - 0.037 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1770 PF08589.10 ORY07355.1 - 0.075 14.0 4.8 0.6 11.1 4.4 2.6 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1770) PduV-EutP PF10662.9 ORY07355.1 - 0.077 12.7 0.1 3.9 7.2 0.1 3.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Myb_DNA-bind_3 PF12776.7 ORY07355.1 - 0.12 13.3 3.2 5.9 8.0 3.4 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain LicD PF04991.13 ORY07355.1 - 0.15 12.2 8.3 0.28 11.3 8.3 1.4 1 0 0 1 1 1 0 LicD family RNA_helicase PF00910.22 ORY07355.1 - 0.15 12.5 0.5 0.64 10.4 0.0 2.2 2 1 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 ORY07355.1 - 0.25 10.9 7.8 0.41 10.2 7.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit N6_N4_Mtase PF01555.18 ORY07355.1 - 0.38 10.4 5.5 0.63 9.7 5.5 1.3 1 0 0 1 1 1 0 DNA methylase DUF2703 PF10865.8 ORY07355.1 - 0.41 10.8 3.9 0.32 11.2 1.8 2.0 2 1 0 2 2 1 0 Domain of unknown function (DUF2703) DUF4075 PF13294.6 ORY07355.1 - 0.51 10.5 0.1 0.51 10.5 0.1 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4075) DUF87 PF01935.17 ORY07355.1 - 1.3 9.0 7.6 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 ORY07355.1 - 1.9 8.2 5.2 15 5.3 0.0 3.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 ORY07355.1 - 2.8 8.0 12.2 6.5 6.8 0.1 3.5 2 2 1 3 3 2 0 Dynamin family HAUS6_N PF14661.6 ORY07355.1 - 4 6.9 13.6 6.8 6.2 13.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus COesterase PF00135.28 ORY07356.1 - 1e-41 143.4 1.4 2e-41 142.4 1.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_M6 PF05547.11 ORY07356.1 - 0.017 13.5 0.2 0.02 13.3 0.2 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Abhydrolase_3 PF07859.13 ORY07356.1 - 0.067 13.0 0.1 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold HAD PF12710.7 ORY07356.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase COesterase PF00135.28 ORY07357.1 - 5.2e-18 65.2 0.0 5.3e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY07357.1 - 0.09 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3958 PF13125.6 ORY07358.1 - 0.0058 16.8 5.7 0.0058 16.8 5.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3958) DUF2703 PF10865.8 ORY07358.1 - 0.044 14.0 0.1 0.052 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DUF4355 PF14265.6 ORY07358.1 - 0.046 14.0 11.4 0.054 13.7 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) COesterase PF00135.28 ORY07359.1 - 1.3e-75 255.2 0.0 4.4e-73 246.9 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY07359.1 - 0.0032 17.3 0.0 0.0086 16.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY07359.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 ORY07360.1 - 2.4e-77 261.0 0.0 4.2e-77 260.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY07360.1 - 0.0032 17.4 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY07360.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 ORY07360.1 - 0.02 14.5 0.1 0.37 10.4 0.1 2.3 2 1 0 2 2 2 0 Putative esterase Wzz PF02706.15 ORY07360.1 - 3.8 7.9 5.2 1.3 9.3 2.2 1.8 2 0 0 2 2 2 0 Chain length determinant protein COesterase PF00135.28 ORY07361.1 - 2.7e-41 142.0 1.4 5.5e-41 141.0 1.4 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY07361.1 - 0.0014 18.5 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 ORY07362.1 - 8.5e-66 222.9 0.1 1.5e-65 222.1 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 ORY07362.1 - 4.2e-05 23.3 0.0 0.94 9.1 0.0 3.1 3 0 0 3 3 3 3 Putative esterase Abhydrolase_3 PF07859.13 ORY07362.1 - 6.3e-05 22.9 0.1 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY07362.1 - 0.0007 19.1 0.6 0.0016 18.0 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family MFS_1 PF07690.16 ORY07363.1 - 3.6e-28 98.5 54.1 1.8e-26 92.9 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY07363.1 - 1.1e-05 24.5 34.0 0.0018 17.2 10.7 3.1 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_4 PF06779.14 ORY07363.1 - 0.76 9.0 29.3 17 4.6 29.1 2.2 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF3087 PF11286.8 ORY07363.1 - 7.8 5.9 11.2 2 7.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) RdRP PF05183.12 ORY07365.1 - 3.3e-161 537.9 0.0 1.6e-160 535.6 0.0 2.0 2 0 0 2 2 2 1 RNA dependent RNA polymerase PET PF06297.14 ORY07365.1 - 0.039 14.2 0.2 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 PET Domain Iron_permease PF04120.12 ORY07366.1 - 8.4e-33 112.9 15.1 1e-13 51.2 0.5 4.2 4 0 0 4 4 4 4 Low affinity iron permease STI1 PF17830.1 ORY07366.1 - 0.095 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 STI1 domain Iron_permease PF04120.12 ORY07367.1 - 8.4e-33 112.9 15.1 1e-13 51.2 0.5 4.2 4 0 0 4 4 4 4 Low affinity iron permease STI1 PF17830.1 ORY07367.1 - 0.095 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 STI1 domain CBAH PF02275.18 ORY07368.1 - 0.0086 15.8 0.2 0.012 15.3 0.2 1.1 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family CBAH PF02275.18 ORY07369.1 - 0.015 15.0 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Helicase_C PF00271.31 ORY07371.1 - 2.1e-10 40.9 0.0 2.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2 PF00096.26 ORY07431.1 - 1.4e-10 41.1 6.9 3.6e-06 27.1 2.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY07431.1 - 5.7e-09 36.0 7.6 5.8e-05 23.3 1.5 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY07431.1 - 7.1e-09 35.8 5.6 5e-05 23.8 1.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY07431.1 - 7.5e-07 29.3 0.3 0.0003 21.1 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY07431.1 - 5.6e-05 23.3 1.4 0.0048 17.1 0.3 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY07431.1 - 0.0031 17.5 2.8 0.014 15.4 0.4 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 ORY07431.1 - 0.008 16.5 2.5 0.02 15.2 2.5 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 ORY07431.1 - 0.022 15.1 0.7 0.091 13.1 0.2 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 ORY07431.1 - 0.026 14.7 0.5 0.081 13.2 0.3 1.8 2 0 0 2 2 2 0 LIM domain zf-LYAR PF08790.11 ORY07431.1 - 0.028 14.3 2.9 0.44 10.5 0.5 2.5 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_9 PF16293.5 ORY07431.1 - 0.04 13.8 0.4 4 7.4 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.9 ORY07431.1 - 0.075 12.8 0.7 0.094 12.4 0.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) IBR PF01485.21 ORY07431.1 - 0.082 13.1 2.6 3.9 7.8 0.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF2256 PF10013.9 ORY07431.1 - 0.12 12.5 1.9 0.26 11.4 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Rad50_zn_hook PF04423.14 ORY07431.1 - 0.15 12.0 1.4 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 ORY07431.1 - 0.57 10.1 7.8 0.92 9.5 3.3 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 ORY07431.1 - 2.2 8.8 7.6 0.38 11.2 1.5 2.6 2 2 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prim_Zn_Ribbon PF08273.12 ORY07431.1 - 3.1 8.2 7.7 18 5.7 0.2 2.3 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-C2H2 PF00096.26 ORY07432.1 - 3.6e-13 49.2 11.6 5.4e-07 29.7 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY07432.1 - 7.4e-10 38.8 9.0 6.2e-05 23.5 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY07432.1 - 4.6e-09 36.3 10.5 3.4e-08 33.6 2.6 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORY07432.1 - 6.6e-05 23.2 0.3 0.24 11.9 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY07432.1 - 0.00039 20.6 0.2 0.17 12.2 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 ORY07432.1 - 0.00092 19.1 2.6 0.84 9.6 0.3 2.4 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORY07432.1 - 0.0017 18.3 1.6 0.023 14.7 0.5 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY07432.1 - 0.0033 17.7 2.6 0.013 15.8 0.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 ORY07432.1 - 0.0043 16.8 8.3 0.3 10.9 0.6 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 ORY07432.1 - 0.0048 16.5 0.9 0.25 11.0 0.2 2.1 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 ORY07432.1 - 0.01 16.5 0.5 0.12 13.1 0.5 1.9 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 ORY07432.1 - 0.012 15.7 0.7 0.012 15.7 0.7 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.6 ORY07432.1 - 0.017 15.0 6.5 1.3 9.0 0.4 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 ORY07432.1 - 0.12 12.5 2.4 0.19 11.9 0.5 1.8 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORY07432.1 - 0.2 11.4 0.5 0.2 11.4 0.5 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 ORY07433.1 - 1e-10 41.4 13.0 1.4e-05 25.2 2.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY07433.1 - 8.3e-09 35.6 10.5 0.00051 20.6 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY07433.1 - 5.6e-07 29.7 15.0 2.4e-06 27.7 4.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 ORY07433.1 - 1.1e-06 28.8 5.3 0.0014 19.0 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY07433.1 - 3.2e-06 27.3 4.5 0.016 15.5 2.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY07433.1 - 0.023 15.0 2.3 1.3 9.4 0.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 ORY07433.1 - 0.052 14.2 1.6 0.26 11.9 0.2 2.4 3 0 0 3 3 3 0 FOXP coiled-coil domain Acyltransf_C PF16076.5 ORY07433.1 - 0.12 12.5 0.3 0.27 11.4 0.3 1.7 1 1 0 1 1 1 0 Acyltransferase C-terminus zf-BED PF02892.15 ORY07433.1 - 0.16 12.0 6.8 6.9 6.8 1.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 ORY07433.1 - 0.22 11.6 4.9 0.4 10.8 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY07434.1 - 1.1e-09 38.1 12.7 0.00016 22.0 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY07434.1 - 1.3e-09 38.0 10.8 3.8e-06 27.1 4.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY07434.1 - 2.5e-08 34.1 10.6 0.0003 21.4 1.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY07434.1 - 8.7e-05 22.7 8.5 0.033 14.5 1.3 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY07434.1 - 0.00015 22.0 1.8 0.088 13.1 0.6 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY07434.1 - 0.00033 21.0 8.9 0.0029 17.9 0.7 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORY07434.1 - 0.00096 19.7 3.8 0.0039 17.8 0.3 2.2 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 ORY07434.1 - 0.021 15.5 1.2 0.22 12.2 1.5 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met2 PF12907.7 ORY07434.1 - 0.036 14.2 2.1 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 Zinc-binding DUF4692 PF15763.5 ORY07434.1 - 0.062 13.8 0.0 0.089 13.3 0.0 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) zf_ZIC PF18366.1 ORY07434.1 - 0.32 11.1 2.5 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-BED PF02892.15 ORY07434.1 - 1.1 9.4 6.5 5.3 7.1 2.6 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 ORY07435.1 - 2.6e-11 43.3 10.2 1.2e-06 28.6 1.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY07435.1 - 3.7e-09 36.6 10.8 2.1e-06 27.9 4.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY07435.1 - 4.7e-07 30.1 13.0 0.0002 21.9 0.7 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY07435.1 - 6.9e-05 23.0 7.3 0.0014 18.8 0.4 2.8 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY07435.1 - 0.00011 22.4 2.4 0.0072 16.7 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY07435.1 - 0.00015 21.7 0.4 0.00015 21.7 0.4 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY07435.1 - 0.01 16.5 2.6 1.3 9.7 0.0 3.0 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 ORY07435.1 - 0.011 15.5 8.1 2.3 8.0 4.6 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORY07435.1 - 0.068 13.6 5.0 0.14 12.6 0.1 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 ORY07435.1 - 0.27 11.4 1.6 18 5.5 0.2 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain FOXP-CC PF16159.5 ORY07435.1 - 0.36 11.5 0.2 0.36 11.5 0.2 2.3 3 0 0 3 3 3 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 ORY07435.1 - 2.4 7.9 5.7 2.7 7.7 0.3 2.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain PHP PF02811.19 ORY07436.1 - 1.8e-06 28.3 0.0 2.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 PHP domain CP2 PF04516.15 ORY07437.1 - 6.5e-54 182.7 1.9 1.1e-53 182.0 1.9 1.4 1 0 0 1 1 1 1 CP2 transcription factor PI3_PI4_kinase PF00454.27 ORY07438.1 - 1.9e-56 191.7 0.0 3.9e-56 190.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 ORY07438.1 - 1.6e-05 25.2 0.8 0.033 14.6 0.0 3.4 2 1 1 3 3 3 2 FKBP12-rapamycin binding domain Cytochrom_B562 PF07361.11 ORY07438.1 - 0.03 15.0 2.0 0.61 10.8 0.3 3.1 3 0 0 3 3 3 0 Cytochrome b562 FATC PF02260.20 ORY07439.1 - 6.8e-12 45.0 0.4 1.2e-11 44.2 0.4 1.5 1 0 0 1 1 1 1 FATC domain Ribosomal_L22e PF01776.17 ORY07440.1 - 1.4e-49 167.0 2.2 1.9e-49 166.6 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family T4_Gp59_N PF08993.10 ORY07440.1 - 0.024 15.1 1.8 0.16 12.4 0.4 2.0 1 1 1 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase IF4E PF01652.18 ORY07441.1 - 3.6e-58 195.8 0.2 4.6e-58 195.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cpn60_TCP1 PF00118.24 ORY07442.1 - 3.4e-151 504.2 19.5 3.9e-151 504.0 19.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 ORY07442.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination Proteasome PF00227.26 ORY07443.1 - 7.6e-59 198.4 0.1 9.6e-59 198.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY07443.1 - 7.1e-14 51.2 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DSPc PF00782.20 ORY07444.1 - 5.7e-18 65.0 0.2 6.7e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY07444.1 - 3.9e-05 23.8 0.1 5.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 ORY07444.1 - 0.00012 21.8 0.1 0.00017 21.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 ORY07444.1 - 0.00016 21.3 0.1 0.00026 20.6 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ORY07444.1 - 0.012 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPn PF14671.6 ORY07444.1 - 0.081 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Init_tRNA_PT PF04179.12 ORY07444.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Ribosomal_L6e PF01159.19 ORY07445.1 - 5.8e-42 142.7 2.0 5.8e-42 142.7 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORY07445.1 - 4.8e-08 33.1 0.2 4.8e-08 33.1 0.2 2.3 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Pkinase PF00069.25 ORY07446.1 - 3.2e-75 252.9 0.1 3.9e-75 252.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07446.1 - 1.3e-37 129.5 0.1 1.9e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY07446.1 - 1.9e-05 24.2 0.0 5.8e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY07446.1 - 0.00011 21.2 0.2 0.0017 17.4 0.2 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY07446.1 - 0.015 14.1 0.1 0.015 14.1 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 ORY07446.1 - 0.033 13.6 0.8 0.1 12.0 0.8 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.27 ORY07447.1 - 5.2e-32 111.6 0.1 4.5e-31 108.6 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY07447.1 - 1.3e-07 31.2 0.2 2.3e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.8 ORY07447.1 - 8.4e-07 28.9 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 MMR_HSR1 PF01926.23 ORY07449.1 - 2.4e-18 66.3 0.0 4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY07449.1 - 2.8e-07 30.2 0.0 3.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY07449.1 - 4.4e-06 26.9 0.0 0.0067 16.5 0.2 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORY07449.1 - 8.2e-06 25.8 0.0 0.00071 19.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY07449.1 - 0.00016 21.3 0.1 0.0013 18.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 ORY07449.1 - 0.0027 17.0 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Septin IIGP PF05049.13 ORY07449.1 - 0.005 16.0 0.2 0.012 14.7 0.2 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 ORY07449.1 - 0.034 14.4 0.1 0.077 13.2 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY07449.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ORY07449.1 - 0.051 14.1 0.0 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 ORY07449.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 ORY07449.1 - 0.089 12.2 0.1 0.5 9.7 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein DUF1631 PF07793.11 ORY07449.1 - 0.18 10.2 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Rhomboid PF01694.22 ORY07450.1 - 3.9e-14 52.9 14.4 3.9e-14 52.9 14.4 1.4 2 0 0 2 2 2 1 Rhomboid family DUF3188 PF11384.8 ORY07450.1 - 0.058 13.1 1.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) EMG1 PF03587.14 ORY07451.1 - 9.5e-82 273.4 0.1 1.1e-81 273.1 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF1641 PF07849.11 ORY07452.1 - 0.16 11.9 0.3 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Glyco_hydro_47 PF01532.20 ORY07453.1 - 1.4e-175 584.6 0.1 1.6e-175 584.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ETF_QO PF05187.13 ORY07454.1 - 5.2e-46 155.1 0.1 8.7e-46 154.4 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 ORY07454.1 - 3.9e-07 29.5 1.7 8.2e-05 21.9 3.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORY07454.1 - 4.2e-07 29.9 2.2 0.00024 20.8 1.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY07454.1 - 8.8e-07 28.4 0.3 4.1e-06 26.3 0.3 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY07454.1 - 1.1e-06 28.8 0.4 8.9e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY07454.1 - 3.1e-06 26.7 0.0 5.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY07454.1 - 3.1e-06 26.6 0.0 3.5e-05 23.2 0.2 2.0 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 ORY07454.1 - 5.4e-05 22.2 0.4 0.016 14.1 1.3 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 ORY07454.1 - 0.0001 22.8 1.2 0.19 12.3 0.9 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY07454.1 - 0.00025 21.1 0.3 0.00056 19.9 0.3 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY07454.1 - 0.00032 19.5 1.4 0.00053 18.8 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 ORY07454.1 - 0.00038 19.9 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY07454.1 - 0.00045 19.6 2.2 0.00069 19.0 2.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 ORY07454.1 - 0.00079 20.0 1.1 0.0019 18.8 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 ORY07454.1 - 0.00086 18.5 0.5 0.0014 17.8 0.5 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 ORY07454.1 - 0.027 13.6 1.3 0.04 13.0 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_10 PF13237.6 ORY07454.1 - 0.13 12.4 0.6 0.29 11.3 0.6 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 ORY07454.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Anoctamin PF04547.12 ORY07455.1 - 0.027 13.3 2.0 0.05 12.4 2.0 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2721 PF11026.8 ORY07455.1 - 0.077 12.9 2.4 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Ribosomal_L35Ae PF01247.18 ORY07456.1 - 6.6e-45 151.2 0.8 8e-45 150.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY07456.1 - 0.024 14.9 0.1 0.81 9.9 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain Nop14 PF04147.12 ORY07457.1 - 4.1e-283 941.8 38.9 4.7e-283 941.6 38.9 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 ORY07457.1 - 2.4e-05 23.8 0.1 2.4e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 Noc2p family Cofilin_ADF PF00241.20 ORY07458.1 - 2.9e-10 40.0 0.0 4.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GET2 PF08690.10 ORY07459.1 - 1.4e-05 24.9 5.0 6.6e-05 22.7 5.0 1.9 1 1 0 1 1 1 1 GET complex subunit GET2 CAML PF14963.6 ORY07459.1 - 0.0087 16.2 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand APG6 PF04111.12 ORY07460.1 - 1.3e-80 269.6 2.5 6e-80 267.4 0.0 2.1 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 ORY07460.1 - 1.8e-31 109.4 24.3 3.1e-31 108.6 24.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF1664 PF07889.12 ORY07460.1 - 0.0068 16.4 7.9 0.02 14.9 5.8 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) FapA PF03961.13 ORY07460.1 - 0.0075 14.9 6.5 0.011 14.4 6.5 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A V_ATPase_I PF01496.19 ORY07460.1 - 0.014 13.3 6.3 0.02 12.9 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 ORY07460.1 - 0.017 14.0 13.1 0.028 13.3 13.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Noelin-1 PF12308.8 ORY07460.1 - 0.018 15.0 4.5 1.1 9.2 0.8 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF1068 PF06364.12 ORY07460.1 - 0.019 14.9 6.5 0.033 14.1 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF3289 PF11692.8 ORY07460.1 - 0.075 12.6 2.0 0.12 11.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) YabA PF06156.13 ORY07460.1 - 0.1 13.2 11.4 0.084 13.5 8.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 ORY07460.1 - 0.16 12.3 18.0 3.2 8.2 14.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.13 ORY07460.1 - 0.22 12.3 9.3 0.17 12.6 3.9 2.6 1 1 1 2 2 2 0 Occludin homology domain FAM76 PF16046.5 ORY07460.1 - 0.34 10.2 5.7 0.57 9.5 5.7 1.4 1 0 0 1 1 1 0 FAM76 protein HAUS-augmin3 PF14932.6 ORY07460.1 - 1.1 8.8 20.2 0.56 9.8 15.7 2.2 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.14 ORY07460.1 - 1.1 9.1 14.1 0.36 10.6 10.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) LOH1CR12 PF10158.9 ORY07460.1 - 1.3 9.0 6.2 0.9 9.6 2.2 2.3 1 1 1 2 2 2 0 Tumour suppressor protein DNA_topoisoIV PF00521.20 ORY07460.1 - 1.6 7.5 7.3 2.6 6.9 7.3 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Exonuc_VII_L PF02601.15 ORY07460.1 - 2.2 7.8 8.6 4.7 6.7 8.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 ORY07460.1 - 4.2 7.7 14.1 10 6.5 2.8 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 ORY07460.1 - 4.6 7.4 21.3 1.7 8.8 16.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 ORY07460.1 - 5.4 7.7 17.7 13 6.4 14.0 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2408 PF10303.9 ORY07460.1 - 6 7.4 11.0 1.5 9.4 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) SKA1 PF07160.12 ORY07460.1 - 6.5 6.5 12.2 0.68 9.7 6.7 2.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 ORY07460.1 - 6.9 5.9 9.9 2.8 7.2 3.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 ORY07460.1 - 9.3 6.6 15.7 3.9 7.8 9.5 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GIT_CC PF16559.5 ORY07460.1 - 10 6.1 10.9 0.9 9.5 4.9 2.4 2 1 1 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-C2H2_jaz PF12171.8 ORY07462.1 - 1e-07 32.0 2.1 1.9e-07 31.2 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY07462.1 - 0.0069 16.7 0.2 0.0095 16.2 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DnaG_DnaB_bind PF08278.11 ORY07462.1 - 0.028 15.0 0.2 0.066 13.8 0.0 1.7 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding zf-met PF12874.7 ORY07462.1 - 0.13 12.6 2.4 0.25 11.8 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ribosomal_L35Ae PF01247.18 ORY07463.1 - 4.1e-45 151.9 0.8 4.6e-45 151.7 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY07463.1 - 0.02 15.1 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain Peptidase_M3 PF01432.20 ORY07464.1 - 5e-102 342.5 0.0 7.7e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Spermine_synth PF01564.17 ORY07465.1 - 1.5e-09 37.5 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_11 PF08241.12 ORY07465.1 - 0.0041 17.7 0.0 0.013 16.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY07465.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY07465.1 - 0.048 14.4 0.0 0.094 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1158 PF06643.11 ORY07465.1 - 0.051 14.1 5.4 0.56 10.7 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1158) DDT PF02791.17 ORY07466.1 - 2.5e-05 24.5 0.2 6.1e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 DDT domain VPS28 PF03997.12 ORY07467.1 - 1.6e-66 223.6 0.6 1.6e-66 223.6 0.6 1.6 2 0 0 2 2 1 1 VPS28 protein ABC_membrane PF00664.23 ORY07467.1 - 2.7e-49 168.3 17.2 1.7e-24 86.9 10.2 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY07467.1 - 5.7e-49 166.2 0.0 4.6e-26 92.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY07467.1 - 1.4e-09 37.7 0.5 0.42 10.0 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY07467.1 - 1.2e-05 25.7 0.1 0.18 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.17 ORY07467.1 - 7.8e-05 22.9 1.0 0.037 14.1 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 ORY07467.1 - 0.0001 22.4 0.5 0.026 14.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 ORY07467.1 - 0.00017 20.7 0.0 0.051 12.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 ORY07467.1 - 0.00019 21.1 0.2 0.3 10.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY07467.1 - 0.00041 20.3 0.1 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY07467.1 - 0.00051 20.3 1.3 1.3 9.3 0.1 3.5 3 1 0 3 3 2 2 AAA domain AAA_21 PF13304.6 ORY07467.1 - 0.001 19.0 2.7 0.18 11.6 0.1 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY07467.1 - 0.0014 18.2 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY07467.1 - 0.0019 18.3 1.8 1.4 8.9 0.1 2.7 2 0 0 2 2 2 2 Dynamin family AAA_PrkA PF08298.11 ORY07467.1 - 0.0069 15.3 0.2 2.7 6.8 0.1 2.3 2 0 0 2 2 2 2 PrkA AAA domain ATP_bind_1 PF03029.17 ORY07467.1 - 0.0079 16.0 0.3 0.37 10.5 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 ORY07467.1 - 0.017 14.9 0.0 4.6 6.9 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein DEAD PF00270.29 ORY07467.1 - 0.017 14.9 0.0 0.39 10.5 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 ORY07467.1 - 0.039 12.9 0.1 0.57 9.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TMEM190 PF15431.6 ORY07467.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 190 AAA_23 PF13476.6 ORY07467.1 - 0.069 13.6 0.7 2.5 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY07467.1 - 0.069 13.1 0.1 13 5.7 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 ORY07467.1 - 0.077 13.5 0.1 26 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY07467.1 - 0.086 11.8 0.1 0.59 9.1 0.0 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 ORY07467.1 - 0.09 12.8 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 ORY07467.1 - 0.096 12.0 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 ORY07467.1 - 0.18 12.2 0.1 10 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 ORY07467.1 - 0.18 10.9 1.1 13 4.9 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain C2 PF00168.30 ORY07468.1 - 1.1e-23 83.4 3.5 4.4e-12 46.2 0.4 2.5 2 0 0 2 2 2 2 C2 domain MMM1 PF10296.9 ORY07468.1 - 0.085 11.9 0.0 0.085 11.9 0.0 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Glyco_hydro_46 PF01374.18 ORY07469.1 - 1.3e-34 119.7 0.0 1.4e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Gon7 PF08738.10 ORY07470.1 - 0.00011 22.2 1.7 0.00013 22.0 1.4 1.3 1 1 0 1 1 1 1 Gon7 family DUF4611 PF15387.6 ORY07470.1 - 0.00074 19.7 5.7 0.001 19.3 5.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Chisel PF15355.6 ORY07470.1 - 0.021 15.1 0.1 0.03 14.6 0.1 1.2 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel DUF305 PF03713.13 ORY07470.1 - 0.054 13.6 0.6 0.057 13.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF305) DUF4746 PF15928.5 ORY07470.1 - 0.077 12.4 8.9 0.082 12.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 ORY07470.1 - 0.27 10.5 5.9 0.29 10.4 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 ORY07470.1 - 2 6.6 7.8 2 6.6 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 ORY07470.1 - 2.4 7.2 8.1 2.7 7.1 8.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ribosomal_60s PF00428.19 ORY07471.1 - 1.9e-25 89.2 11.7 2.2e-25 89.1 11.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Peptidase_M64 PF09471.10 ORY07472.1 - 3.7e-32 111.9 0.0 1.1e-31 110.4 0.0 1.7 1 1 0 1 1 1 1 IgA Peptidase M64 MG2 PF01835.19 ORY07472.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 MG2 domain Ank_4 PF13637.6 ORY07474.1 - 0.00067 20.2 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY07474.1 - 0.011 16.1 0.1 0.019 15.4 0.1 1.4 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 ORY07474.1 - 0.049 14.2 0.1 0.28 11.9 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 ORY07474.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) UFD1 PF03152.14 ORY07475.1 - 1.3e-42 145.2 0.0 2e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Peptidase_M64 PF09471.10 ORY07477.1 - 5.7e-29 101.4 0.0 1.1e-27 97.3 0.0 2.1 1 1 0 1 1 1 1 IgA Peptidase M64 Ribosomal_L30_N PF08079.12 ORY07478.1 - 1.5e-22 79.6 18.3 1.5e-22 79.6 18.3 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ORY07478.1 - 4e-16 58.6 1.5 4e-16 58.6 1.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Taxilin PF09728.9 ORY07478.1 - 0.0025 17.0 1.6 0.0029 16.8 1.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Speriolin_N PF15058.6 ORY07478.1 - 0.031 14.4 1.2 0.65 10.1 2.7 1.9 1 1 1 2 2 2 0 Speriolin N terminus ATP-synt_ab PF00006.25 ORY07479.1 - 1.7e-74 250.1 0.0 2.9e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY07479.1 - 2.1e-49 167.0 0.3 3.9e-49 166.2 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY07479.1 - 4.5e-20 71.9 1.9 1.3e-19 70.4 1.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ORY07479.1 - 0.061 13.5 2.3 0.72 10.0 1.8 2.5 2 1 0 2 2 2 0 HAS barrel domain ATPase_2 PF01637.18 ORY07479.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Radical_SAM_C PF16199.5 ORY07479.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 Radical_SAM C-terminal domain Pro_isomerase PF00160.21 ORY07480.1 - 1.2e-44 152.4 0.2 1.3e-44 152.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L19 PF01245.20 ORY07481.1 - 4.2e-23 81.4 1.4 1.4e-22 79.7 0.3 1.9 1 1 1 2 2 2 1 Ribosomal protein L19 WD40 PF00400.32 ORY07482.1 - 4.1e-11 43.2 2.3 0.27 12.2 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07482.1 - 0.0017 18.6 0.0 5.8 7.3 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Fip1 PF05182.13 ORY07483.1 - 5.2e-25 86.7 2.1 9.5e-25 85.9 2.1 1.5 1 0 0 1 1 1 1 Fip1 motif PFK PF00365.20 ORY07484.1 - 2.1e-198 657.3 0.6 4.1e-107 357.7 0.1 2.2 2 0 0 2 2 2 2 Phosphofructokinase Ank_2 PF12796.7 ORY07484.1 - 5.5e-15 55.7 1.3 1.2e-10 41.8 0.1 3.9 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY07484.1 - 1.2e-12 48.0 0.4 3.3e-10 40.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY07484.1 - 4.7e-11 42.7 0.7 1.2e-05 25.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY07484.1 - 6e-07 29.3 0.2 0.011 16.2 0.0 4.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY07484.1 - 5.9e-06 26.5 2.9 0.014 15.8 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Pfk_N PF18468.1 ORY07484.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 ORY07484.1 - 0.016 14.8 0.1 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF2001 PF09393.10 ORY07484.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein FYVE PF01363.21 ORY07485.1 - 1.4e-11 44.3 3.0 1.4e-11 44.3 3.0 3.1 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_11 PF17123.5 ORY07485.1 - 0.018 14.8 7.0 0.02 14.6 2.3 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 ORY07485.1 - 0.04 14.3 1.9 0.04 14.3 1.9 3.9 4 1 1 5 5 5 0 Ring finger domain zf-RING_UBOX PF13445.6 ORY07485.1 - 0.064 13.3 2.2 0.064 13.3 2.2 4.3 5 0 0 5 5 5 0 RING-type zinc-finger zf-4CXXC_R1 PF10497.9 ORY07485.1 - 1.3 9.2 9.7 0.18 12.0 1.2 2.6 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.6 ORY07485.1 - 4.8 7.2 19.2 7.8 6.5 1.7 3.8 2 1 2 4 4 4 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY07485.1 - 7.3 6.5 19.9 3.5 7.6 0.1 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Adaptin_N PF01602.20 ORY07486.1 - 8.2e-146 486.6 10.8 1.2e-145 486.1 10.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORY07486.1 - 7.3e-23 81.0 2.9 1.8e-22 79.8 2.9 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORY07486.1 - 8.6e-10 38.9 13.7 6.7e-08 32.7 0.2 5.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 ORY07486.1 - 0.0004 20.2 0.2 0.015 15.0 0.0 3.1 3 0 0 3 3 3 1 DNA alkylation repair enzyme HEAT_2 PF13646.6 ORY07486.1 - 0.01 16.2 1.5 4.3 7.8 0.1 3.9 4 0 0 4 4 4 0 HEAT repeats RIX1 PF08167.12 ORY07486.1 - 0.037 13.8 0.2 0.5 10.1 0.0 2.7 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis AAR2 PF05282.11 ORY07486.1 - 0.23 10.8 3.9 0.15 11.4 0.5 2.4 3 0 0 3 3 3 0 AAR2 protein Dynamin_M PF01031.20 ORY07487.1 - 2e-107 358.7 0.3 1.2e-104 349.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 ORY07487.1 - 9.6e-58 194.9 0.2 3.7e-57 193.0 0.2 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY07487.1 - 1.5e-32 111.5 6.2 4.6e-32 110.0 6.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY07487.1 - 7.2e-05 22.9 0.6 0.00049 20.2 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF848 PF05852.11 ORY07487.1 - 0.0076 16.4 0.1 0.021 15.0 0.1 1.7 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) AAA_16 PF13191.6 ORY07487.1 - 0.046 14.1 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Vps5 PF09325.10 ORY07488.1 - 7.9e-19 68.1 17.2 4.1e-18 65.8 17.2 1.8 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY07488.1 - 2.4e-17 63.0 0.1 1.6e-15 57.0 0.0 2.6 2 0 0 2 2 2 1 PX domain BAR PF03114.18 ORY07488.1 - 0.0058 16.3 7.7 0.01 15.5 7.7 1.4 1 0 0 1 1 1 1 BAR domain APG6_N PF17675.1 ORY07488.1 - 5.2 7.6 16.7 7.2 7.1 11.9 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region LMBR1 PF04791.16 ORY07488.1 - 6 5.7 5.9 5.9 5.7 3.2 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein STT3 PF02516.14 ORY07489.1 - 2.7e-148 494.9 41.7 1.8e-143 479.0 38.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 ORY07489.1 - 2.3e-05 24.6 13.6 2.3e-05 24.6 13.6 3.8 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SVM_signal PF12113.8 ORY07489.1 - 0.18 11.7 1.8 0.51 10.3 1.8 1.8 1 0 0 1 1 1 0 SVM protein signal sequence Vezatin PF12632.7 ORY07490.1 - 3.1e-23 82.6 12.9 2.2e-21 76.4 12.9 2.4 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes GH97_N PF14508.6 ORY07490.1 - 0.0083 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl-hydrolase 97 N-terminal PRP9_N PF16958.5 ORY07490.1 - 0.54 10.3 7.9 0.9 9.6 1.5 2.7 3 0 0 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus ARD PF03079.14 ORY07491.1 - 1.3e-51 174.9 0.2 1.4e-51 174.7 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ORY07491.1 - 1.5e-10 40.6 0.0 3.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORY07491.1 - 1.9e-06 27.8 0.0 6.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ORY07491.1 - 2.2e-05 24.1 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 ORY07491.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.12 ORY07491.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SpoOE-like PF09388.10 ORY07491.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein COX15-CtaA PF02628.15 ORY07492.1 - 5.3e-108 360.9 5.5 6.1e-108 360.7 5.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 ORY07492.1 - 0.093 12.8 1.3 2 8.5 0.3 2.4 2 0 0 2 2 2 0 Fumarate reductase subunit C KilA-N PF04383.13 ORY07494.1 - 2.4e-05 24.1 0.1 0.00047 20.0 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain OTCace PF00185.24 ORY07495.1 - 1.1e-51 175.0 0.0 1.9e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ORY07495.1 - 1.6e-46 158.0 0.2 3.3e-46 157.0 0.1 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ribosomal_L21e PF01157.18 ORY07496.1 - 1.1e-47 160.0 5.8 1.1e-47 160.0 5.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e S4 PF01479.25 ORY07497.1 - 9.6e-13 47.6 1.0 9.6e-13 47.6 1.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY07497.1 - 4.4e-05 24.3 0.3 8.7e-05 23.4 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DKCLD PF08068.12 ORY07498.1 - 8.2e-35 118.7 0.1 1.5e-33 114.6 0.2 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 ORY07498.1 - 6.9e-23 80.6 0.6 1.4e-22 79.5 0.6 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 ORY07498.1 - 4.3e-21 74.6 3.4 9e-21 73.6 3.4 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 ORY07498.1 - 4.4e-20 72.5 9.0 7.9e-20 71.7 0.2 3.8 2 1 0 2 2 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 ORY07498.1 - 0.00092 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 ORY07498.1 - 0.16 12.3 9.9 0.22 11.8 9.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 ORY07498.1 - 0.26 11.4 32.7 0.42 10.7 32.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AP3D1 PF06375.11 ORY07498.1 - 0.26 11.5 19.6 0.43 10.8 19.6 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 U1snRNP70_N PF12220.8 ORY07498.1 - 0.93 10.2 15.0 2.6 8.8 15.0 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RR_TM4-6 PF06459.12 ORY07498.1 - 1.8 8.4 22.0 2.5 7.9 22.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 ORY07498.1 - 2.1 8.2 20.6 4.2 7.2 20.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus DUF4604 PF15377.6 ORY07498.1 - 2.4 8.6 27.0 3.6 8.0 27.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Paf1 PF03985.13 ORY07498.1 - 2.5 7.0 19.6 3.6 6.5 19.6 1.2 1 0 0 1 1 1 0 Paf1 SecE PF00584.20 ORY07499.1 - 1.5e-16 60.0 0.0 1.7e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SAS-6_N PF16531.5 ORY07499.1 - 0.11 13.1 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal NOG1_N PF17835.1 ORY07500.1 - 1.3e-54 184.4 2.4 3.7e-54 183.0 2.4 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 ORY07500.1 - 6.8e-29 99.6 2.5 1.8e-28 98.2 2.5 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 ORY07500.1 - 6.7e-28 96.3 0.1 1.9e-27 94.8 0.1 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 ORY07500.1 - 3.6e-17 62.5 0.0 9.7e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY07500.1 - 1.1e-09 38.0 0.1 4e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY07500.1 - 0.00046 20.1 0.1 0.45 10.4 0.0 3.2 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY07500.1 - 0.0012 19.0 4.4 0.79 9.8 0.0 3.7 3 1 1 4 4 4 2 Dynamin family PI3K_1B_p101 PF10486.9 ORY07500.1 - 0.0042 15.0 6.7 0.0052 14.6 6.7 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Roc PF08477.13 ORY07500.1 - 0.011 15.9 0.0 0.1 12.8 0.0 2.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY07500.1 - 0.037 14.4 0.1 0.39 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 ORY07500.1 - 0.058 13.9 0.6 2 9.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 ORY07500.1 - 0.065 12.8 4.3 0.13 11.8 0.2 3.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.21 ORY07501.1 - 1e-47 161.8 0.1 1.2e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY07501.1 - 5.2e-22 78.2 0.0 6e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY07501.1 - 8.2e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY07501.1 - 2.6e-11 43.3 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY07501.1 - 4.8e-09 35.9 0.0 6.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY07501.1 - 1.4e-08 34.8 0.0 4e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORY07501.1 - 3.5e-08 33.0 0.8 4.2e-05 22.9 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 ORY07501.1 - 0.00051 19.6 0.0 0.014 15.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 ORY07501.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 ORY07501.1 - 0.019 15.2 0.0 0.44 10.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY07501.1 - 0.019 15.0 0.1 0.97 9.5 0.2 2.5 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.12 ORY07501.1 - 0.039 13.9 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 ORY07501.1 - 0.063 12.8 0.6 0.14 11.7 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 ORY07501.1 - 0.071 12.7 0.0 9.9 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.11 ORY07501.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E AAA PF00004.29 ORY07501.1 - 0.082 13.3 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY07501.1 - 0.082 13.4 0.2 0.14 12.7 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 ORY07501.1 - 0.11 12.9 0.0 20 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain JTB PF05439.12 ORY07502.1 - 1.3e-13 50.9 5.3 3.3e-13 49.6 5.3 1.6 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) PepSY_TM PF03929.16 ORY07502.1 - 0.14 11.8 0.0 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 PepSY-associated TM region PEGA PF08308.11 ORY07502.1 - 0.2 11.6 0.0 0.64 10.0 0.0 1.8 2 0 0 2 2 2 0 PEGA domain PAC1 PF16094.5 ORY07503.1 - 2.3e-14 53.3 0.1 3.2e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 CRM1_C PF08767.11 ORY07504.1 - 8.2e-05 21.9 1.2 0.00022 20.5 1.2 1.7 1 0 0 1 1 1 1 CRM1 C terminal IBN_N PF03810.19 ORY07504.1 - 0.0031 17.4 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain ANAPC5 PF12862.7 ORY07504.1 - 0.053 13.6 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 SnAC PF14619.6 ORY07505.1 - 2.9 8.6 7.5 40 4.9 7.5 2.2 1 1 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex AMP-binding PF00501.28 ORY07506.1 - 1.7e-93 313.5 0.0 2.2e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY07506.1 - 5.9e-10 40.0 0.1 1.4e-09 38.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rhodanese PF00581.20 ORY07507.1 - 1.3e-13 51.4 0.0 1.5e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain HSP20 PF00011.21 ORY07508.1 - 0.00026 21.1 0.6 0.0036 17.4 0.6 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Cas_Cas5d PF09704.10 ORY07508.1 - 0.079 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) CBAH PF02275.18 ORY07509.1 - 0.014 15.0 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family RSN1_7TM PF02714.15 ORY07578.1 - 2.2e-80 269.9 19.3 2.2e-80 269.9 19.3 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY07578.1 - 2.8e-32 112.3 0.0 4.1e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY07578.1 - 7.5e-10 38.8 0.9 7.5e-10 38.8 0.9 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 ORY07578.1 - 4.1e-08 33.3 0.0 8.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter HLH PF00010.26 ORY07579.1 - 5.3e-11 42.3 1.1 1.1e-10 41.2 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIR2 PF02146.17 ORY07580.1 - 2.7e-46 157.7 0.0 3.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family cpYpsA PF12694.7 ORY07580.1 - 0.083 12.7 0.0 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family UPF0029 PF01205.19 ORY07581.1 - 3e-33 114.3 0.1 5.8e-33 113.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 ORY07581.1 - 8.9e-17 61.4 0.6 1.8e-16 60.4 0.6 1.5 1 0 0 1 1 1 1 RWD domain PfkB PF00294.24 ORY07582.1 - 0.031 13.6 0.5 0.064 12.6 0.5 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase PTH2 PF01981.16 ORY07583.1 - 3.3e-48 162.8 0.0 4e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4299 PF14132.6 ORY07585.1 - 0.023 14.1 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) NTP_transf_8 PF12281.8 ORY07585.1 - 0.073 13.1 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase Cornichon PF03311.14 ORY07586.1 - 5.6e-46 155.8 9.8 6.4e-46 155.7 9.8 1.0 1 0 0 1 1 1 1 Cornichon protein TIM21 PF08294.11 ORY07586.1 - 1.3 8.9 3.2 0.65 9.9 0.5 1.8 2 0 0 2 2 2 0 TIM21 ATP19 PF11022.8 ORY07587.1 - 1.6e-18 66.8 0.1 2e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Pyr_redox_2 PF07992.14 ORY07588.1 - 3.7e-64 216.8 0.8 5.1e-64 216.3 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY07588.1 - 1.8e-32 111.9 0.2 3.8e-32 110.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY07588.1 - 2.6e-21 75.9 4.2 1.5e-19 70.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY07588.1 - 1.4e-13 50.8 1.9 6.1e-13 48.7 1.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ORY07588.1 - 5.8e-06 25.8 2.3 0.0012 18.2 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 ORY07588.1 - 2.6e-05 23.5 1.3 0.00059 19.0 0.5 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 ORY07588.1 - 3.7e-05 23.1 0.4 0.00038 19.7 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ORY07588.1 - 5.1e-05 22.7 4.4 0.046 13.0 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ORY07588.1 - 0.00011 21.7 2.5 0.00066 19.1 1.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORY07588.1 - 0.00014 21.8 5.4 0.00061 19.7 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ORY07588.1 - 0.00052 18.8 9.9 0.0044 15.8 1.5 3.7 3 1 1 4 4 4 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY07588.1 - 0.0039 16.3 4.1 0.0039 16.3 4.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY07588.1 - 0.013 15.5 0.6 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.6 ORY07588.1 - 0.013 15.7 3.7 0.013 15.7 3.7 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 ORY07588.1 - 0.017 15.6 0.6 6.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding F420_oxidored PF03807.17 ORY07588.1 - 0.034 14.7 4.6 1.4 9.5 0.3 3.4 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 ORY07588.1 - 0.036 13.7 12.5 0.22 11.1 4.7 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 ORY07588.1 - 0.073 12.3 0.4 0.16 11.2 0.4 1.5 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 ORY07588.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 ORY07588.1 - 0.15 12.6 0.1 10 6.7 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 ORY07588.1 - 0.17 12.0 1.0 1.3 9.2 0.1 2.6 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 ORY07588.1 - 1.2 8.3 9.7 4.3 6.5 1.2 3.1 2 1 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 ORY07588.1 - 3.4 6.6 4.6 2.3 7.2 0.8 2.2 2 1 1 3 3 3 0 Lycopene cyclase protein CUE PF02845.16 ORY07591.1 - 0.037 13.7 0.0 4.1 7.2 0.0 3.1 2 0 0 2 2 2 0 CUE domain KorB PF08535.10 ORY07591.1 - 0.19 11.8 0.4 56 3.9 0.0 3.4 3 0 0 3 3 3 0 KorB domain DUF2530 PF10745.9 ORY07591.1 - 0.52 10.6 1.9 0.95 9.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) 2OG-FeII_Oxy_3 PF13640.6 ORY07592.1 - 5e-10 40.1 0.0 8.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 ORY07592.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.20 ORY07592.1 - 0.081 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF727 PF05303.12 ORY07593.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Alginate_lyase PF05426.12 ORY07594.1 - 6.8e-11 42.2 4.0 2e-10 40.7 4.0 1.6 1 1 0 1 1 1 1 Alginate lyase Queuosine_synth PF02547.15 ORY07594.1 - 0.06 12.5 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein WD40 PF00400.32 ORY07595.1 - 0.00022 21.9 2.1 0.064 14.1 0.2 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07595.1 - 0.0052 17.1 0.0 0.57 10.5 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BCAS3 PF12490.8 ORY07595.1 - 0.0053 16.3 0.3 0.19 11.2 0.0 2.4 1 1 1 2 2 2 1 Breast carcinoma amplified sequence 3 zf-C2H2 PF00096.26 ORY07596.1 - 9.2e-24 82.5 26.1 4.3e-06 26.9 1.7 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY07596.1 - 1e-21 76.3 26.3 4.8e-07 29.9 0.7 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY07596.1 - 3.7e-11 42.9 26.9 0.0041 17.8 0.9 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY07596.1 - 0.00013 22.2 9.0 0.72 10.2 0.8 3.0 1 1 2 3 3 3 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY07596.1 - 0.028 15.0 9.9 3.6 8.3 0.2 4.0 1 1 3 4 4 4 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 ORY07596.1 - 0.031 14.3 3.2 0.96 9.5 0.5 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 ORY07596.1 - 0.094 13.0 6.0 8.6 6.8 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY07596.1 - 0.29 11.6 4.3 4.6 7.8 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORY07596.1 - 0.48 10.4 8.0 1.8 8.5 0.1 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORY07596.1 - 4 7.5 16.4 1.1 9.3 0.6 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger DAHP_synth_1 PF00793.20 ORY07597.1 - 3e-100 334.6 0.0 3.7e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Hist_deacetyl PF00850.19 ORY07598.1 - 1.3e-82 277.7 0.2 3.2e-82 276.5 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain IGPD PF00475.18 ORY07599.1 - 2.6e-60 202.9 0.7 3.7e-60 202.4 0.7 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MAD PF05557.13 ORY07600.1 - 2.9e-87 293.6 75.8 2.9e-87 293.6 75.8 2.0 2 0 0 2 2 2 1 Mitotic checkpoint protein PHD PF00628.29 ORY07600.1 - 1.8e-08 34.2 11.0 3.1e-08 33.4 11.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY07600.1 - 0.0018 17.8 9.0 0.0039 16.7 9.0 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 ORY07600.1 - 8.7 6.4 8.8 18 5.4 8.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SecA_SW PF07516.13 ORY07602.1 - 0.0022 18.1 0.1 0.024 14.7 0.1 2.2 2 0 0 2 2 2 1 SecA Wing and Scaffold domain Pex26 PF07163.12 ORY07602.1 - 0.045 13.1 0.1 0.17 11.1 0.1 2.1 2 0 0 2 2 2 0 Pex26 protein SurA_N_3 PF13624.6 ORY07602.1 - 0.16 11.7 1.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 SurA N-terminal domain Ank_5 PF13857.6 ORY07603.1 - 5.2e-22 77.6 1.2 2.7e-10 40.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY07603.1 - 1.5e-20 73.2 2.3 4.3e-08 33.5 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY07603.1 - 3.8e-18 65.9 0.3 2.1e-17 63.5 0.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY07603.1 - 1.5e-15 55.7 0.6 0.0001 22.4 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 ORY07603.1 - 2e-11 43.8 0.3 0.0063 16.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Asp PF00026.23 ORY07604.1 - 1.3e-96 323.8 0.3 1.5e-96 323.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY07604.1 - 4e-16 59.8 0.5 3.5e-13 50.2 0.4 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY07604.1 - 0.00013 22.6 0.1 0.41 11.3 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY07604.1 - 0.0099 16.4 0.0 2.2 8.9 0.0 2.6 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ORY07604.1 - 0.16 11.8 0.1 0.62 9.8 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal 6PF2K PF01591.18 ORY07605.1 - 4.4e-71 238.7 0.0 6.2e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY07605.1 - 2.5e-23 82.8 0.0 4.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY07605.1 - 0.00019 21.6 0.0 0.00057 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Chs7 PF12271.8 ORY07606.1 - 1.2e-74 251.3 22.5 1.4e-74 251.1 22.5 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone ATP1G1_PLM_MAT8 PF02038.16 ORY07606.1 - 0.16 11.4 2.8 0.37 10.3 0.3 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Col_cuticle_N PF01484.17 ORY07606.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.7 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain FixQ PF05545.11 ORY07606.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.0 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ DIOX_N PF14226.6 ORY07607.1 - 6.5e-25 88.2 0.1 1.1e-24 87.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY07607.1 - 3.8e-23 81.9 0.0 6.5e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PBD PF00786.28 ORY07608.1 - 1.8e-07 31.4 0.1 3e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain 2-Hacid_dh_C PF02826.19 ORY07609.1 - 2.9e-52 176.6 0.0 5.1e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY07609.1 - 3.1e-35 120.8 0.0 4.2e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY07609.1 - 7.9e-06 26.1 0.2 3.6e-05 24.0 0.0 2.2 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 ORY07609.1 - 0.021 14.6 0.2 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 ACT domain Glyco_hydro_20 PF00728.22 ORY07610.1 - 1.8e-42 146.0 0.1 1.5e-34 119.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY07610.1 - 3.4e-07 31.1 0.0 1.7e-05 25.6 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Matrilin_ccoil PF10393.9 ORY07610.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Cyclin PF08613.11 ORY07611.1 - 2.5e-13 50.7 0.0 3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY07611.1 - 4.9e-05 23.1 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Oxidored_FMN PF00724.20 ORY07612.1 - 5.8e-70 236.2 0.0 7.5e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAM72 PF14976.6 ORY07613.1 - 3.2e-23 82.5 1.5 3.7e-23 82.3 1.5 1.0 1 0 0 1 1 1 1 FAM72 protein FAM72 PF14976.6 ORY07614.1 - 3.9e-44 150.3 2.0 4.6e-44 150.1 2.0 1.1 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORY07614.1 - 0.0015 18.7 1.4 0.021 15.0 0.4 2.1 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PHO4 PF01384.20 ORY07615.1 - 9e-117 389.9 15.4 1e-116 389.7 15.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family PRA-CH PF01502.18 ORY07616.1 - 0.082 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase Lactamase_B_2 PF12706.7 ORY07617.1 - 1.4e-27 96.5 0.0 1.7e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY07617.1 - 3e-09 37.2 0.6 1.3e-08 35.1 0.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY07617.1 - 0.036 13.5 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PH PF00169.29 ORY07618.1 - 0.0006 20.3 0.1 0.0016 18.9 0.0 1.8 2 0 0 2 2 2 1 PH domain C2 PF00168.30 ORY07619.1 - 2.9e-88 290.9 2.8 6.4e-19 68.2 0.0 6.4 6 0 0 6 6 6 6 C2 domain SMP_LBD PF17047.5 ORY07619.1 - 0.0017 17.9 0.0 0.039 13.4 0.0 2.3 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DIL PF01843.19 ORY07620.1 - 2.5e-25 88.7 10.7 3.8e-25 88.2 6.9 2.7 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 ORY07620.1 - 5.6e-19 68.5 0.0 1e-11 45.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY07620.1 - 8e-10 38.7 0.0 0.00045 20.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY07620.1 - 1.5e-09 37.9 0.0 2.7e-06 27.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY07620.1 - 7.9e-06 26.3 0.0 0.00091 19.8 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY07620.1 - 0.0096 16.4 0.0 5.7 7.9 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Cadherin-like PF12733.7 ORY07620.1 - 0.037 14.5 0.1 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Ras PF00071.22 ORY07621.1 - 3.3e-57 192.6 0.1 3.8e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY07621.1 - 8.4e-21 74.4 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY07621.1 - 1.9e-08 33.9 0.1 2.6e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY07621.1 - 6.6e-06 25.8 0.3 5.7e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY07621.1 - 8.5e-05 22.5 0.2 0.019 14.8 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY07621.1 - 0.0096 15.5 0.4 0.096 12.2 0.4 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY07621.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 ORY07621.1 - 0.02 14.4 0.0 0.038 13.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit IMP_cyclohyd PF07826.11 ORY07621.1 - 0.036 13.7 0.1 0.082 12.5 0.0 1.6 2 0 0 2 2 2 0 IMP cyclohydrolase-like protein Septin PF00735.18 ORY07621.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Septin Gly_kinase PF02595.15 ORY07621.1 - 0.087 11.8 0.0 9.3 5.1 0.0 2.1 2 0 0 2 2 2 0 Glycerate kinase family AAA_25 PF13481.6 ORY07621.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 ORY07621.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Biopterin_H PF00351.21 ORY07623.1 - 1.9e-170 566.3 0.0 2.5e-170 565.8 0.0 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 ORY07623.1 - 2.5e-06 27.1 0.2 9.6e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 ORY07623.1 - 0.00064 20.3 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain YtxH PF12732.7 ORY07623.1 - 0.02 15.4 0.5 29 5.3 0.0 3.2 3 0 0 3 3 3 0 YtxH-like protein Reprolysin_2 PF13574.6 ORY07624.1 - 0.065 13.1 0.1 0.068 13.1 0.1 1.0 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SapB_1 PF05184.15 ORY07625.1 - 5.7e-13 48.6 0.9 9e-13 48.0 0.9 1.3 1 0 0 1 1 1 1 Saposin-like type B, region 1 SapB_2 PF03489.17 ORY07625.1 - 0.00019 21.5 2.3 0.00021 21.3 1.1 1.8 2 0 0 2 2 2 1 Saposin-like type B, region 2 AAA PF00004.29 ORY07626.1 - 1.8e-06 28.4 0.0 6.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ORY07626.1 - 0.00012 22.2 0.0 0.00047 20.2 0.0 2.2 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY07626.1 - 0.0038 17.6 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 ORY07626.1 - 0.0049 16.3 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_22 PF13401.6 ORY07626.1 - 0.0086 16.3 0.3 0.97 9.7 0.0 2.9 3 1 0 3 3 1 1 AAA domain DUF815 PF05673.13 ORY07626.1 - 0.0089 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY07626.1 - 0.01 16.3 0.0 0.042 14.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY07626.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 ORY07626.1 - 0.02 14.0 0.0 0.071 12.2 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 ORY07626.1 - 0.023 14.0 0.0 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 ORY07626.1 - 0.028 14.8 0.0 0.09 13.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 ORY07626.1 - 0.035 13.6 0.0 0.094 12.2 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 ORY07626.1 - 0.036 14.1 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY07626.1 - 0.039 13.8 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 ORY07626.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 ORY07626.1 - 0.047 12.7 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 ORY07626.1 - 0.057 12.8 0.3 8.6 5.6 0.0 2.8 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.6 ORY07626.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORY07626.1 - 0.096 12.4 0.2 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ORY07626.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY07626.1 - 0.18 11.9 0.0 0.56 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NmrA PF05368.13 ORY07627.1 - 2.3e-25 89.5 0.0 3e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY07627.1 - 2.2e-17 63.6 0.0 1.4e-16 60.9 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY07627.1 - 3e-05 23.6 0.0 0.0013 18.2 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY07627.1 - 8.5e-05 22.5 0.1 0.00016 21.7 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 ORY07627.1 - 0.0069 15.6 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 ORY07627.1 - 0.0074 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 ORY07627.1 - 0.015 15.6 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.25 ORY07627.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY07627.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 ORY07627.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 LpxI N-terminal domain Proteasome PF00227.26 ORY07628.1 - 3.3e-51 173.5 0.0 4e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 ORY07628.1 - 1.5e-11 43.5 0.1 1.5e-11 43.5 0.1 2.2 2 0 0 2 2 2 1 Proteasome beta subunits C terminal EB PF01683.18 ORY07629.1 - 0.00063 20.0 8.7 0.00063 20.0 8.7 2.6 2 1 0 2 2 2 1 EB module DUF4448 PF14610.6 ORY07629.1 - 0.0033 17.2 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4668 PF15701.5 ORY07629.1 - 0.012 15.5 4.0 0.023 14.5 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Orf78 PF06024.12 ORY07629.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.4 2 0 0 2 2 2 0 Orf78 (ac78) DUF2116 PF09889.9 ORY07629.1 - 0.22 11.5 5.2 0.2 11.6 1.9 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Tmemb_9 PF05434.11 ORY07629.1 - 6.7 6.6 10.3 0.13 12.1 2.6 1.9 2 0 0 2 2 2 0 TMEM9 Kelch_1 PF01344.25 ORY07630.1 - 5.5e-24 83.5 19.1 4.5e-07 29.3 0.2 8.1 8 2 0 8 8 8 5 Kelch motif Kelch_6 PF13964.6 ORY07630.1 - 2.9e-23 81.3 19.2 2.8e-06 27.4 1.3 6.8 4 2 3 7 7 7 6 Kelch motif Kelch_4 PF13418.6 ORY07630.1 - 1e-20 73.4 18.2 1.8e-06 27.8 0.6 7.3 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY07630.1 - 1.2e-14 53.6 3.0 0.00066 19.6 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 ORY07630.1 - 2e-11 43.6 11.6 0.0038 17.2 0.2 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 ORY07630.1 - 4.5e-09 36.4 24.4 0.00061 20.0 1.0 7.1 7 1 0 7 7 7 2 Galactose oxidase, central domain zf-C2H2 PF00096.26 ORY07631.1 - 2.6e-13 49.6 8.6 6.3e-07 29.5 3.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY07631.1 - 4.9e-10 39.4 7.1 1.9e-05 25.1 1.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY07631.1 - 1.2e-09 38.2 11.6 2.3e-07 30.9 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 ORY07631.1 - 6e-05 22.7 3.5 0.0022 17.7 0.7 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY07631.1 - 7.4e-05 22.6 6.9 0.0013 18.7 1.3 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY07631.1 - 0.00031 21.0 3.5 0.0018 18.6 0.6 2.7 2 1 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY07631.1 - 0.00069 19.7 1.8 0.13 12.4 0.1 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_8 PF15909.5 ORY07631.1 - 0.0011 19.2 0.9 0.0034 17.6 0.8 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY07631.1 - 0.0014 18.9 0.3 0.0014 18.9 0.3 2.6 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 ORY07631.1 - 0.0015 18.4 1.8 0.0015 18.4 1.8 2.3 2 1 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 ORY07631.1 - 0.012 15.5 4.3 0.19 11.7 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-DNA_Pol PF08996.10 ORY07631.1 - 0.03 14.1 0.3 0.032 14.0 0.3 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 ORY07631.1 - 0.096 12.7 3.7 0.86 9.7 3.7 2.1 1 1 0 1 1 1 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 ORY07631.1 - 0.29 11.1 5.5 0.65 10.0 5.5 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 ORY07631.1 - 0.51 10.8 4.1 1.4 9.4 0.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 ORY07631.1 - 1.1 9.1 11.5 4.2 7.2 3.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain PLDc_2 PF13091.6 ORY07632.1 - 2.2e-26 92.3 0.1 3.5e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 ORY07632.1 - 1.9e-07 30.9 0.1 0.00084 19.0 0.0 2.2 2 0 0 2 2 2 2 FAM83 A-H PLDc PF00614.22 ORY07632.1 - 0.0024 18.0 0.6 0.005 17.0 0.6 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif ERCC4 PF02732.15 ORY07633.1 - 6.9e-15 55.6 2.2 9.3e-15 55.2 0.0 2.2 1 1 1 2 2 2 1 ERCC4 domain tRNA_bind_2 PF13725.6 ORY07633.1 - 0.087 12.5 10.6 0.2 11.3 10.6 1.5 1 0 0 1 1 1 0 Possible tRNA binding domain OmpH PF03938.14 ORY07633.1 - 0.23 11.8 13.0 1.5 9.2 11.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 ORY07633.1 - 1.2 8.6 6.0 2.5 7.6 6.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit SNARE_assoc PF09335.11 ORY07634.1 - 9.7e-20 71.2 2.6 9.7e-20 71.2 2.6 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF2892 PF11127.8 ORY07634.1 - 2.5 8.2 5.5 1.3 9.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) HABP4_PAI-RBP1 PF04774.15 ORY07635.1 - 5.5e-06 27.2 0.5 7.2e-06 26.8 0.3 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family PRCH PF03967.13 ORY07635.1 - 0.12 12.6 0.3 0.14 12.4 0.3 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Glyco_hydro_61 PF03443.14 ORY07636.1 - 0.0004 20.4 0.3 0.00061 19.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORY07636.1 - 0.024 15.3 1.8 0.039 14.6 1.8 1.3 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY07637.1 - 0.0024 17.8 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORY07637.1 - 3.4 8.3 16.6 0.05 14.3 3.5 2.6 2 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ORY07638.1 - 0.0082 16.1 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ORY07638.1 - 0.018 15.7 1.2 0.14 12.8 0.2 1.8 1 1 1 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 ORY07639.1 - 0.0046 17.6 3.9 0.0046 17.6 3.9 2.1 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SSI PF00720.17 ORY07640.1 - 1.4e-21 76.2 0.1 1.8e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Subtilisin inhibitor-like PAN_3 PF08277.12 ORY07641.1 - 0.12 12.2 0.6 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 PAN-like domain Arrestin_C PF02752.22 ORY07642.1 - 1.5e-14 54.6 1.2 1.4e-10 41.7 0.3 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY07642.1 - 1.2e-10 41.7 0.0 1.4e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY07642.1 - 0.00029 20.6 0.1 0.0013 18.5 0.0 2.0 2 1 0 2 2 2 1 Arrestin_N terminal like Rgp1 PF08737.10 ORY07642.1 - 0.0012 18.1 0.6 0.014 14.6 0.1 2.5 2 1 0 3 3 3 1 Rgp1 Vps26 PF03643.15 ORY07642.1 - 0.041 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 ORY07643.1 - 2.4e-14 53.9 3.4 9e-10 39.1 0.8 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY07643.1 - 3.4e-12 46.6 0.0 1.2e-10 41.6 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY07643.1 - 0.00031 20.5 0.0 0.00052 19.8 0.0 1.5 1 1 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 ORY07643.1 - 0.0083 15.3 0.1 0.014 14.6 0.1 1.6 1 1 0 1 1 1 1 Rgp1 Vps26 PF03643.15 ORY07643.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Velvet PF11754.8 ORY07644.1 - 6.3e-21 75.4 0.0 2.5e-09 37.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor PS_Dcarbxylase PF02666.15 ORY07698.1 - 5.2e-35 120.8 0.0 6.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 ORY07698.1 - 2.7e-28 98.7 0.2 5.4e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 ORY07698.1 - 0.0053 16.7 0.1 3.9 7.5 0.0 2.9 2 1 1 3 3 3 2 RnfC Barrel sandwich hybrid domain NMO PF03060.15 ORY07699.1 - 3.1e-47 161.6 0.1 4.1e-47 161.2 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY07699.1 - 5.1e-05 22.4 0.1 0.00038 19.6 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY07699.1 - 0.18 10.8 0.8 0.29 10.1 0.8 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase HlyIII PF03006.20 ORY07700.1 - 2e-47 161.8 19.8 3.1e-47 161.2 19.8 1.3 1 0 0 1 1 1 1 Haemolysin-III related Polysacc_deac_1 PF01522.21 ORY07701.1 - 2e-34 118.2 0.0 3.5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY07701.1 - 0.00015 21.1 0.0 0.00031 20.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 GFRP PF06399.13 ORY07701.1 - 0.0083 16.0 0.3 2.9 7.9 0.0 3.2 2 2 0 3 3 3 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) RAP PF08373.10 ORY07701.1 - 0.026 14.6 0.1 0.99 9.6 0.1 2.4 2 0 0 2 2 2 0 RAP domain DUF2334 PF10096.9 ORY07701.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF5371 PF17341.2 ORY07701.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5371) AMP-binding PF00501.28 ORY07702.1 - 4.2e-88 295.8 0.0 4.9e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY07702.1 - 9.7e-22 77.7 1.1 1.7e-21 77.0 1.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_S4 PF00163.19 ORY07704.1 - 0.001 19.9 0.5 0.001 19.9 0.5 3.0 3 1 0 3 3 3 1 Ribosomal protein S4/S9 N-terminal domain HMMR_N PF15905.5 ORY07704.1 - 0.0054 16.3 11.4 0.0054 16.3 11.4 4.2 2 2 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 ORY07704.1 - 0.01 16.0 8.9 0.01 16.0 8.9 4.4 2 2 2 4 4 4 0 Tropomyosin like PKcGMP_CC PF16808.5 ORY07704.1 - 0.058 13.3 0.3 0.058 13.3 0.3 4.8 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bcr-Abl_Oligo PF09036.10 ORY07704.1 - 0.28 11.2 11.2 0.36 10.9 0.9 4.4 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Golgin_A5 PF09787.9 ORY07704.1 - 0.31 10.5 52.1 0.13 11.7 3.5 3.9 2 2 1 3 3 3 0 Golgin subfamily A member 5 Csm1_N PF18504.1 ORY07704.1 - 0.41 11.0 0.0 0.41 11.0 0.0 8.8 4 2 4 9 9 9 0 Csm1 N-terminal domain Spc7 PF08317.11 ORY07704.1 - 0.72 8.7 53.3 0.018 13.9 13.8 3.8 2 2 1 3 3 3 0 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 ORY07704.1 - 2.5 8.5 0.0 2.5 8.5 0.0 5.5 7 1 0 7 7 7 0 Valyl tRNA synthetase tRNA binding arm Lectin_N PF03954.14 ORY07704.1 - 6 6.6 17.7 2.6 7.8 0.9 4.6 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain Peptidase_C48 PF02902.19 ORY07705.1 - 2.8e-23 82.9 1.3 3.7e-23 82.5 1.3 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WW PF00397.26 ORY07706.1 - 1.4e-11 44.3 2.4 2.9e-11 43.2 0.6 2.4 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 ORY07706.1 - 0.37 10.8 32.2 31 4.5 32.2 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) eIF_4EBP PF05456.11 ORY07707.1 - 2.8e-33 114.3 1.2 3.4e-33 114.0 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HAUS2 PF15003.6 ORY07708.1 - 6.4e-21 75.0 2.2 7.2e-21 74.8 2.2 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 AAA_23 PF13476.6 ORY07708.1 - 0.059 13.9 1.5 0.079 13.5 1.5 1.3 1 1 0 1 1 1 0 AAA domain Phage-tail_1 PF09097.10 ORY07708.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 1 0 1 1 1 0 Baseplate structural protein, domain 1 Baculo_PEP_C PF04513.12 ORY07708.1 - 0.64 10.0 5.2 8.7 6.4 4.9 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEMT PF04191.13 ORY07709.1 - 9e-57 190.0 14.3 1e-31 109.4 3.3 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 ORY07709.1 - 0.00024 20.9 0.1 0.00093 19.0 0.0 1.9 1 1 1 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 ORY07709.1 - 0.0003 21.3 0.1 0.0014 19.1 0.1 2.1 1 1 0 1 1 1 1 SKICH domain Tetraspanin PF00335.20 ORY07709.1 - 0.0023 17.7 0.5 0.083 12.6 0.1 2.6 2 0 0 2 2 2 1 Tetraspanin family GP24_25 PF17388.2 ORY07709.1 - 0.034 14.1 1.2 0.081 12.9 1.2 1.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 DUF520 PF04461.13 ORY07709.1 - 1.4 9.0 4.4 0.52 10.4 1.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF520) C2 PF00168.30 ORY07710.1 - 2.3e-13 50.3 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 C2 domain CHAP PF05257.16 ORY07711.1 - 5.7e-11 42.8 0.1 8.6e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 CHAP domain Amidase_6 PF12671.7 ORY07711.1 - 0.024 14.8 2.1 0.42 10.7 0.8 2.2 2 1 0 2 2 2 0 Putative amidase domain BST2 PF16716.5 ORY07712.1 - 0.0023 18.4 4.0 0.0023 18.4 4.0 16.3 11 5 7 18 18 18 5 Bone marrow stromal antigen 2 TPR_5 PF12688.7 ORY07712.1 - 5.6 7.2 10.2 1.6 9.0 2.9 4.0 3 0 0 3 3 3 0 Tetratrico peptide repeat DUF1365 PF07103.11 ORY07713.1 - 7.8e-69 232.0 0.2 8.9e-69 231.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.20 ORY07714.1 - 4.4e-80 268.9 0.2 5.3e-80 268.6 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY07714.1 - 6.9e-09 36.3 0.0 1.4e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY07714.1 - 2.9e-07 31.0 0.0 5.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY07714.1 - 1.8e-05 24.7 0.1 3.4e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY07714.1 - 9.4e-05 22.2 0.1 0.00017 21.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ORY07714.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 ORY07714.1 - 0.028 15.2 0.0 0.075 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 ORY07714.1 - 0.048 13.3 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_3 PF01596.17 ORY07714.1 - 0.074 12.2 0.1 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase Amino_oxidase PF01593.24 ORY07715.1 - 2e-15 57.0 0.0 8.2e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY07715.1 - 2.1e-13 50.3 0.1 2e-12 47.1 0.1 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY07715.1 - 1.7e-08 34.4 0.8 1.9e-07 31.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY07715.1 - 2.3e-07 30.3 0.1 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY07715.1 - 2.3e-05 24.4 0.3 0.032 14.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY07715.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY07715.1 - 0.00043 19.1 0.1 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ORY07715.1 - 0.02 15.5 1.1 0.14 12.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY07715.1 - 0.023 13.8 0.7 0.029 13.4 0.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY07715.1 - 0.032 13.5 0.7 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY07715.1 - 0.056 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 ORY07715.1 - 0.068 11.6 0.1 0.92 7.8 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like APA3_viroporin PF11289.8 ORY07715.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Coronavirus accessory protein 3a ApbA PF02558.16 ORY07715.1 - 0.14 11.7 0.2 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Amidohydro_1 PF01979.20 ORY07716.1 - 5.4e-66 223.3 1.0 8.8e-66 222.6 1.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY07716.1 - 4.8e-57 191.5 3.8 9.9e-57 190.5 3.8 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORY07716.1 - 1.1e-39 134.4 0.1 3e-39 133.0 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 ORY07716.1 - 1.5e-38 131.1 0.1 3.9e-38 129.8 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORY07716.1 - 6.8e-05 22.5 0.1 0.00052 19.6 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family RhoGAP PF00620.27 ORY07717.1 - 3.3e-26 92.0 0.1 1.1e-25 90.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 ORY07717.1 - 1.5e-16 60.9 0.2 3.9e-15 56.3 0.1 3.0 2 1 0 2 2 2 1 MyTH4 domain WW PF00397.26 ORY07717.1 - 0.0041 17.2 1.8 1.4 9.1 0.7 2.5 2 0 0 2 2 2 2 WW domain EF-hand_1 PF00036.32 ORY07718.1 - 7.2e-05 22.1 0.9 0.0003 20.1 0.9 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORY07718.1 - 0.00012 22.4 4.9 0.00022 21.6 0.4 2.8 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY07718.1 - 0.00033 20.4 2.4 0.035 13.9 0.6 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY07718.1 - 0.00055 19.7 1.7 0.0019 18.0 0.6 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 ORY07718.1 - 0.0015 17.9 1.4 0.0055 16.2 1.4 2.0 1 0 0 1 1 1 1 EF hand Frankia_peptide PF14407.6 ORY07718.1 - 0.13 12.3 0.5 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Bap31 PF05529.12 ORY07719.1 - 1.9e-41 141.1 4.0 3.3e-41 140.3 4.0 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ORY07719.1 - 1.9e-05 24.6 9.0 1.9e-05 24.6 9.0 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Fzo_mitofusin PF04799.13 ORY07719.1 - 0.2 11.2 3.2 0.29 10.7 3.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region ISG65-75 PF11727.8 ORY07719.1 - 0.95 8.6 12.9 1.2 8.3 12.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4337 PF14235.6 ORY07719.1 - 3 7.9 7.2 7 6.8 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ThrE PF06738.12 ORY07720.1 - 9.1e-51 172.5 17.0 4.7e-47 160.4 0.8 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY07720.1 - 6.3e-11 42.5 26.1 2.3e-08 34.3 12.9 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE SPATA19 PF15212.6 ORY07720.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial DUF373 PF04123.13 ORY07720.1 - 0.22 10.9 11.8 0.085 12.3 6.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF373) G-alpha PF00503.20 ORY07721.1 - 5.2e-110 367.9 0.6 6.1e-110 367.7 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY07721.1 - 1.9e-15 56.7 0.3 8.2e-10 38.4 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY07721.1 - 4.2e-06 26.3 0.1 0.086 12.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY07721.1 - 0.0029 17.8 0.2 0.55 10.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORY07721.1 - 0.047 13.0 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY07721.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMP_C2CD2L PF18696.1 ORY07721.1 - 0.18 11.7 0.3 0.91 9.3 0.1 2.0 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain DUF3357 PF11837.8 ORY07722.1 - 0.059 13.8 0.5 0.18 12.2 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) N-glycanase_N PF09112.10 ORY07722.1 - 0.2 11.5 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal RGS PF00615.19 ORY07723.1 - 2.6e-18 66.4 0.7 9.6e-18 64.6 0.1 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain HTH_IclR PF09339.10 ORY07723.1 - 0.14 12.0 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain Asp PF00026.23 ORY07724.1 - 1.4e-61 208.7 0.0 1.6e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY07724.1 - 1.6e-06 28.5 0.0 0.0018 18.6 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY07724.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY07724.1 - 0.11 13.1 0.0 37 5.1 0.0 2.8 2 1 0 3 3 3 0 Aspartyl protease Cation_efflux PF01545.21 ORY07725.1 - 5.5e-21 75.2 11.5 6.9e-21 74.9 11.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY07725.1 - 7.4e-12 45.2 0.1 1.4e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PhoLip_ATPase_C PF16212.5 ORY07725.1 - 0.067 12.9 4.1 0.098 12.4 4.1 1.2 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal GPR_Gpa2_C PF11970.8 ORY07726.1 - 0.089 12.9 0.2 0.089 12.9 0.2 2.4 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Holin_BhlA PF10960.8 ORY07726.1 - 0.78 9.7 3.5 1.9 8.5 0.3 2.7 2 1 0 2 2 2 0 BhlA holin family Brix PF04427.18 ORY07727.1 - 9e-41 140.1 0.1 1.3e-40 139.5 0.1 1.3 1 0 0 1 1 1 1 Brix domain LysM PF01476.20 ORY07728.1 - 0.00081 19.4 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain TssN PF17555.2 ORY07729.1 - 1.4 8.3 10.0 1.8 7.9 10.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Cu2_monooxygen PF01082.20 ORY07730.1 - 5.2e-27 94.6 0.1 9.6e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 ORY07730.1 - 2e-20 73.3 0.1 6e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 DOMON domain Cu2_monoox_C PF03712.15 ORY07730.1 - 4.9e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Rotamase PF00639.21 ORY07731.1 - 8.9e-17 61.8 0.0 1.3e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ORY07731.1 - 2.4e-09 37.7 0.0 4.9e-09 36.8 0.0 1.4 2 0 0 2 2 2 1 PPIC-type PPIASE domain WW PF00397.26 ORY07731.1 - 1.5e-08 34.6 0.8 1.5e-08 34.6 0.8 1.5 2 0 0 2 2 2 1 WW domain PNP_phzG_C PF10590.9 ORY07731.1 - 0.00096 19.2 2.8 0.0049 16.9 3.2 2.0 2 1 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Rotamase_2 PF13145.6 ORY07731.1 - 0.13 13.1 0.0 0.18 12.6 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Glyco_hyd_101C PF17451.2 ORY07731.1 - 0.18 12.1 0.5 0.32 11.3 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DnaJ PF00226.31 ORY07732.1 - 7.8e-22 77.2 0.9 1.8e-21 76.0 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 ORY07732.1 - 6.8e-18 64.2 2.4 1.1e-17 63.5 2.4 1.3 1 0 0 1 1 1 1 CSL zinc finger FAM195 PF14799.6 ORY07732.1 - 0.07 13.5 0.1 0.09 13.1 0.1 1.2 1 0 0 1 1 1 0 FAM195 family WD40 PF00400.32 ORY07733.1 - 9e-18 64.3 2.8 0.00086 20.1 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07733.1 - 1.5e-09 38.1 0.3 0.0074 16.6 0.0 4.2 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY07733.1 - 1.5e-06 27.8 0.0 0.6 9.4 0.0 3.9 4 0 0 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 ORY07733.1 - 0.015 14.2 0.1 1.6 7.6 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase2 PF03162.13 ORY07734.1 - 8e-33 113.3 0.0 8.8e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY07734.1 - 1.7e-08 34.8 0.0 1.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY07734.1 - 0.00021 21.0 0.0 0.00022 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY07734.1 - 0.00028 20.7 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FAM76 PF16046.5 ORY07735.1 - 0.0052 16.2 0.5 0.006 16.0 0.5 1.2 1 0 0 1 1 1 1 FAM76 protein Csm1_N PF18504.1 ORY07735.1 - 0.0056 17.0 3.2 0.0056 17.0 3.2 3.3 2 1 2 4 4 4 1 Csm1 N-terminal domain Troponin PF00992.20 ORY07735.1 - 0.074 13.4 13.4 0.12 12.6 13.4 1.3 1 0 0 1 1 1 0 Troponin Jnk-SapK_ap_N PF09744.9 ORY07735.1 - 0.85 9.8 18.5 1.4 9.2 18.5 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_23 PF13476.6 ORY07735.1 - 1.3 9.5 12.1 2.1 8.8 12.1 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 ORY07735.1 - 4.2 5.2 8.9 5.3 4.8 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 ORY07735.1 - 5.6 6.2 8.1 8 5.7 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CP2 PF04516.15 ORY07737.1 - 2.3e-54 184.1 0.0 3.9e-54 183.4 0.0 1.4 1 1 0 1 1 1 1 CP2 transcription factor Sec-ASP3 PF15432.6 ORY07737.1 - 0.024 14.8 0.6 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 AP4E_app_platf PF14807.6 ORY07738.1 - 1.8e-09 37.8 0.0 5.8e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Coatomer_g_Cpla PF16381.5 ORY07738.1 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform SPATA3 PF15662.5 ORY07739.1 - 0.05 14.2 1.2 0.092 13.4 1.2 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family PAP_central PF04928.17 ORY07740.1 - 3.7e-115 383.2 0.0 5.5e-115 382.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY07740.1 - 2.9e-53 180.0 0.0 5.9e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY07740.1 - 4.9e-10 39.6 0.0 2.2e-09 37.5 0.0 2.1 1 1 1 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORY07740.1 - 0.04 13.7 0.2 0.082 12.7 0.2 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain rRNA_processing PF08524.11 ORY07741.1 - 3.3e-16 59.7 28.7 1.7e-15 57.3 28.7 1.8 1 1 0 1 1 1 1 rRNA processing CDC45 PF02724.14 ORY07741.1 - 0.12 10.7 11.5 0.12 10.6 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Pyrophosphatase PF00719.19 ORY07742.1 - 2.7e-58 196.3 0.7 5.3e-58 195.3 0.2 1.7 3 0 0 3 3 3 1 Inorganic pyrophosphatase Malic_M PF03949.15 ORY07742.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Chorismate_bind PF00425.18 ORY07743.1 - 5.5e-99 330.9 0.0 3.3e-98 328.4 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ORY07743.1 - 1.8e-30 106.0 0.1 2e-28 99.4 0.0 3.4 3 1 0 4 4 4 1 Anthranilate synthase component I, N terminal region Glyco_hydro_85 PF03644.13 ORY07744.1 - 2.7e-87 293.0 2.7 3.8e-87 292.5 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Dynein_light PF01221.18 ORY07745.1 - 2.5e-42 143.1 1.9 2.7e-42 143.0 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 ORY07745.1 - 0.052 13.3 0.9 0.54 10.0 0.1 2.0 1 1 1 2 2 2 0 Immunity protein 48 Ectatomin PF06457.11 ORY07745.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Ectatomin Ribosomal_S17e PF00833.18 ORY07749.1 - 1.2e-64 215.7 0.2 1.4e-64 215.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 U-box PF04564.15 ORY07750.1 - 0.00035 20.7 0.1 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 U-box domain Myb_DNA-binding PF00249.31 ORY07750.1 - 0.009 16.2 0.1 0.24 11.6 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Phage_lysozyme2 PF18013.1 ORY07750.1 - 0.031 14.3 3.7 3.7 7.6 1.5 2.7 2 0 0 2 2 2 0 Phage tail lysozyme RSN1_7TM PF02714.15 ORY07751.1 - 5.9e-70 235.7 23.5 5.9e-70 235.7 23.5 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY07751.1 - 9.2e-38 129.5 3.1 9.2e-38 129.5 3.1 3.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY07751.1 - 2.1e-35 122.5 0.0 3.1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Alginate_lyase PF05426.12 ORY07752.1 - 9.3e-74 248.4 0.0 1.1e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase Vac_ImportDeg PF09783.9 ORY07753.1 - 4.2e-58 195.7 2.3 1.1e-57 194.4 2.3 1.6 1 1 0 1 1 1 1 Vacuolar import and degradation protein zf-C2H2 PF00096.26 ORY07754.1 - 3.8e-12 45.9 10.2 1.3e-05 25.3 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY07754.1 - 1.6e-07 31.5 7.6 0.001 19.7 2.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY07754.1 - 2.6e-07 30.8 0.4 2.6e-07 30.8 0.4 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY07754.1 - 6.1e-05 22.9 7.2 8e-05 22.5 0.7 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY07754.1 - 0.00089 19.0 3.0 0.0056 16.4 0.3 2.2 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 ORY07754.1 - 0.0021 17.9 4.2 0.33 10.9 1.0 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORY07754.1 - 0.22 11.9 3.7 7.9 6.9 0.5 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY07754.1 - 0.23 11.9 1.9 7.8 7.0 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type LapA_dom PF06305.11 ORY07755.1 - 0.012 15.5 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain BatD PF13584.6 ORY07755.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 ORY07755.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Orthoreo_P10 PF07204.11 ORY07756.1 - 0.025 14.5 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DMT_YdcZ PF04657.13 ORY07756.1 - 0.04 14.2 0.7 0.057 13.7 0.3 1.5 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ DUF1223 PF06764.11 ORY07756.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) LapA_dom PF06305.11 ORY07757.1 - 0.018 14.8 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Gram_pos_anchor PF00746.21 ORY07757.1 - 0.16 11.9 0.3 0.3 11.0 0.3 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif G-patch PF01585.23 ORY07758.1 - 2e-11 43.6 0.8 4.1e-11 42.6 0.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY07758.1 - 0.00039 20.5 0.8 0.00039 20.5 0.8 2.5 2 0 0 2 2 2 1 G-patch domain FixO PF02433.15 ORY07758.1 - 0.021 14.3 0.2 0.032 13.7 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO zf-met2 PF12907.7 ORY07759.1 - 1.8e-16 59.9 2.4 2.8e-16 59.3 2.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 ORY07759.1 - 1.9e-06 28.7 13.3 1.9e-06 28.7 13.3 1.8 2 0 0 2 2 2 1 4F5 protein family Amino_oxidase PF01593.24 ORY07814.1 - 3.8e-73 247.3 0.1 9.2e-72 242.7 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY07814.1 - 2.6e-15 56.4 1.0 7.7e-15 54.9 0.8 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY07814.1 - 2e-07 31.0 1.1 6.7e-07 29.2 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY07814.1 - 6.7e-07 29.8 0.6 2.1e-05 25.0 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY07814.1 - 2.4e-06 26.9 0.1 5.5e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY07814.1 - 3e-06 26.7 0.1 3.1e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY07814.1 - 5.5e-06 25.8 1.1 5.5e-06 25.8 1.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY07814.1 - 1e-05 24.4 0.2 0.00015 20.6 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ORY07814.1 - 1.3e-05 24.8 0.4 2.2e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY07814.1 - 8.3e-05 22.0 0.7 0.00016 21.0 0.7 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORY07814.1 - 0.00032 20.1 1.0 0.00058 19.2 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY07814.1 - 0.00037 19.9 0.2 0.013 14.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY07814.1 - 0.0028 16.2 0.2 0.0043 15.5 0.2 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like IlvN PF07991.12 ORY07814.1 - 0.012 15.1 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 ORY07814.1 - 0.017 15.5 0.9 0.04 14.4 0.9 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 ORY07814.1 - 0.022 13.9 0.2 0.036 13.1 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY07814.1 - 0.047 13.7 1.4 0.081 12.9 0.3 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding THF_DHG_CYH_C PF02882.19 ORY07814.1 - 0.053 12.8 0.4 0.26 10.6 0.1 2.3 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 ORY07814.1 - 0.053 12.6 0.4 0.08 12.0 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 ORY07814.1 - 0.056 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ORY07814.1 - 0.14 12.4 0.2 0.81 10.0 0.2 2.2 2 0 0 2 2 2 0 TrkA-N domain Glucosamine_iso PF01182.20 ORY07815.1 - 1.6e-20 74.0 0.0 2.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sec62 PF03839.16 ORY07816.1 - 1.1e-50 172.2 4.2 2.3e-50 171.1 3.9 1.5 1 1 1 2 2 2 1 Translocation protein Sec62 DEP PF00610.21 ORY07816.1 - 0.00043 20.3 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FYRC PF05965.14 ORY07817.1 - 1.8e-21 76.1 0.0 4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 ORY07817.1 - 1.4e-19 69.7 0.3 2.8e-19 68.7 0.3 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus SlyX PF04102.12 ORY07817.1 - 0.0062 17.1 1.0 0.019 15.6 1.0 1.8 1 0 0 1 1 1 1 SlyX Laminin_II PF06009.12 ORY07817.1 - 0.0064 16.5 0.8 0.012 15.6 0.8 1.4 1 0 0 1 1 1 1 Laminin Domain II UPF0242 PF06785.11 ORY07817.1 - 0.0098 16.0 3.5 0.018 15.1 3.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 ORY07817.1 - 0.011 16.2 0.8 0.026 15.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 ORY07817.1 - 0.05 13.6 3.9 0.14 12.2 3.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMEM192 PF14802.6 ORY07817.1 - 0.17 10.9 0.9 0.26 10.4 0.9 1.2 1 0 0 1 1 1 0 TMEM192 family YabA PF06156.13 ORY07817.1 - 0.18 12.5 0.9 0.37 11.5 0.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Glucosamine_iso PF01182.20 ORY07818.1 - 1.5e-20 74.1 0.0 2.2e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ctf8 PF09696.10 ORY07819.1 - 4.1e-13 49.9 0.8 5e-11 43.1 0.1 2.2 1 1 1 2 2 2 2 Ctf8 Amidohydro_1 PF01979.20 ORY07820.1 - 5.5e-25 88.4 0.5 7.4e-25 88.0 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY07820.1 - 2.6e-06 27.2 0.1 3.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY07821.1 - 2.3e-23 83.1 0.5 3.2e-23 82.6 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY07821.1 - 1.9e-06 27.7 0.0 2.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Glucosamine_iso PF01182.20 ORY07822.1 - 2.1e-20 73.6 0.0 3.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glucosamine_iso PF01182.20 ORY07823.1 - 4.1e-20 72.6 0.0 7.7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NADH_B2 PF14813.6 ORY07823.1 - 0.0039 16.9 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Mob1_phocein PF03637.17 ORY07824.1 - 6.5e-82 273.6 0.0 7.8e-82 273.3 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family BAR PF03114.18 ORY07825.1 - 4.2e-42 144.4 7.7 5.3e-42 144.1 7.7 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY07825.1 - 3.4e-07 30.2 6.6 7.5e-07 29.1 6.6 1.6 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 ORY07825.1 - 0.00061 19.4 6.4 0.0076 15.8 6.4 2.2 1 1 0 1 1 1 1 Arfaptin-like domain Vps5 PF09325.10 ORY07825.1 - 0.0022 17.6 4.6 0.016 14.7 4.6 1.9 1 1 1 2 2 2 1 Vps5 C terminal like UPF0184 PF03670.13 ORY07825.1 - 0.008 16.5 1.9 1.7 9.1 0.0 3.4 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0184) DUF99 PF01949.16 ORY07825.1 - 0.04 13.3 0.7 0.088 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF99 IL11 PF07400.11 ORY07825.1 - 0.075 12.7 0.6 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Interleukin 11 BLOC1_2 PF10046.9 ORY07825.1 - 0.12 12.7 5.4 3.7 7.9 0.0 3.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 ORY07825.1 - 0.15 12.4 3.8 1.3 9.3 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GPS2_interact PF15784.5 ORY07825.1 - 0.15 12.6 3.9 0.71 10.3 0.2 2.5 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Ku_C PF03730.14 ORY07825.1 - 0.19 12.4 2.1 7.2 7.4 0.1 2.8 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF948 PF06103.11 ORY07825.1 - 0.21 11.9 1.9 1.8 8.9 0.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 ORY07825.1 - 0.42 9.9 4.4 0.53 9.6 3.7 1.5 1 1 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 ORY07825.1 - 1.2 8.3 3.7 6.8 5.8 1.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein Cyclin_N PF00134.23 ORY07826.1 - 1.3e-11 44.3 0.5 2.6e-11 43.3 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1878 PF08963.10 ORY07826.1 - 0.069 13.6 1.5 0.26 11.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) YjeF_N PF03853.15 ORY07827.1 - 1.4e-33 116.2 0.0 2.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 ORY07827.1 - 9.7e-07 29.6 6.7 9.7e-07 29.6 6.7 2.5 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 ORY07827.1 - 0.00036 20.6 0.1 0.0013 18.8 0.1 2.0 1 1 0 1 1 1 1 Scd6-like Sm domain DUF5096 PF17019.5 ORY07827.1 - 0.13 12.1 0.0 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5096) Tyrosinase PF00264.20 ORY07828.1 - 0.0099 16.2 0.0 0.0099 16.2 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 ORY07829.1 - 3.7e-40 138.6 2.9 2.4e-39 135.9 2.9 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase Pex24p PF06398.11 ORY07830.1 - 2.9e-38 131.8 29.7 3.6e-37 128.2 29.7 2.1 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.22 ORY07830.1 - 6.4e-14 51.6 9.1 1.2e-13 50.7 9.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 ORY07830.1 - 0.14 12.1 4.2 0.3 11.0 4.2 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 ORY07830.1 - 0.59 10.5 4.9 1.1 9.7 4.9 1.4 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 ORY07830.1 - 1.2 9.0 6.5 2.4 8.1 6.5 1.5 1 0 0 1 1 1 0 PHD-finger Reticulon PF02453.17 ORY07830.1 - 1.7 8.6 9.1 2.7 8.0 6.3 2.5 1 1 1 2 2 2 0 Reticulon MitMem_reg PF13012.6 ORY07831.1 - 2.2e-23 82.8 0.2 4e-23 82.0 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY07831.1 - 3.5e-23 81.8 0.1 5.9e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 ORY07831.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Med8 PF10232.9 ORY07832.1 - 1.5e-09 37.8 5.1 2.1e-09 37.3 5.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF3546 PF12066.8 ORY07832.1 - 0.036 14.2 0.5 0.18 12.0 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3546) PQ-loop PF04193.14 ORY07833.1 - 0.045 13.5 0.2 0.045 13.5 0.2 1.9 2 0 0 2 2 2 0 PQ loop repeat DUF2104 PF09877.9 ORY07833.1 - 0.08 13.2 1.9 0.37 11.1 1.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) AA_permease PF00324.21 ORY07834.1 - 1.6e-135 452.4 38.4 2e-135 452.1 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY07834.1 - 1.5e-39 136.0 41.3 1.9e-39 135.7 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 ORY07834.1 - 0.022 15.5 0.0 0.022 15.5 0.0 4.7 5 0 0 5 5 5 0 PrgI family protein bZIP_1 PF00170.21 ORY07835.1 - 2.1e-15 56.6 12.5 2.1e-15 56.6 12.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY07835.1 - 4.9e-14 52.2 10.2 4.9e-14 52.2 10.2 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY07835.1 - 1.4e-07 31.9 5.2 2.5e-07 31.1 5.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 ORY07835.1 - 0.005 17.0 1.2 0.01 16.1 1.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper Fungal_TACC PF12709.7 ORY07835.1 - 0.0065 16.9 2.6 0.012 16.0 2.6 1.5 1 0 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins Nnf1 PF03980.14 ORY07835.1 - 0.023 15.1 2.1 0.042 14.2 2.1 1.4 1 0 0 1 1 1 0 Nnf1 IFP_35_N PF07334.13 ORY07835.1 - 0.031 14.3 1.0 0.071 13.2 1.0 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TSC22 PF01166.18 ORY07835.1 - 0.036 14.4 0.8 0.074 13.4 0.8 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1192 PF06698.11 ORY07835.1 - 0.046 13.8 1.1 1 9.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.15 ORY07835.1 - 0.066 13.0 1.8 0.14 11.9 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4436 PF14494.6 ORY07836.1 - 1.4e-28 99.8 0.2 1.8e-28 99.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Virul_fac_BrkB PF03631.15 ORY07836.1 - 1.4 8.5 9.1 0.95 9.0 0.0 2.7 2 1 0 2 2 2 0 Virulence factor BrkB DUF4097 PF13349.6 ORY07837.1 - 1.6e-05 24.4 3.6 7e-05 22.3 3.6 2.1 1 1 0 1 1 1 1 Putative adhesin Myb_DNA-bind_4 PF13837.6 ORY07838.1 - 5.7e-13 49.1 1.9 5.9e-13 49.0 0.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY07838.1 - 6.8e-05 23.0 2.3 0.00013 22.0 1.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 ORY07838.1 - 0.00047 21.1 2.0 0.014 16.4 0.2 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY07838.1 - 0.0012 19.0 0.9 0.0012 19.0 0.9 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain THP2 PF09432.10 ORY07838.1 - 0.11 12.5 0.8 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Tho complex subunit THP2 Myb_DNA-bind_5 PF13873.6 ORY07838.1 - 0.13 12.4 5.8 0.095 12.8 2.3 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY07838.1 - 0.49 10.7 5.1 0.26 11.6 0.6 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EST1 PF10374.9 ORY07838.1 - 5.4 7.7 8.0 0.51 11.0 1.9 2.2 1 1 1 2 2 2 0 Telomerase activating protein Est1 Glycos_transf_4 PF00953.21 ORY07839.1 - 1.1e-34 119.7 17.5 1.1e-34 119.7 17.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 PLA2G12 PF06951.11 ORY07840.1 - 3.2e-06 27.2 4.8 4.7e-06 26.6 4.8 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Pribosyltran PF00156.27 ORY07841.1 - 3.3e-15 56.0 0.1 4.4e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.22 ORY07843.1 - 9.5e-168 558.5 0.0 1.1e-167 558.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 ORY07844.1 - 2.6e-287 952.6 7.2 5.9e-123 410.8 0.1 4.0 2 2 2 4 4 4 4 Aldehyde dehydrogenase family DUF1122 PF06557.11 ORY07844.1 - 0.024 14.1 0.0 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1122) Eisosome1 PF12757.7 ORY07844.1 - 0.045 14.0 0.1 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Eisosome protein 1 UPF0193 PF05250.11 ORY07844.1 - 0.072 12.9 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) MerE PF05052.12 ORY07844.1 - 0.19 11.7 0.5 34 4.4 0.1 2.6 2 0 0 2 2 2 0 MerE protein BsuBI_PstI_RE PF06616.11 ORY07844.1 - 0.2 11.0 0.0 18 4.6 0.0 2.3 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain HHV-1_VABD PF16852.5 ORY07844.1 - 2 8.5 4.0 40 4.3 0.3 2.7 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain SPX PF03105.19 ORY07845.1 - 4e-35 122.4 10.5 1.8e-21 77.6 5.7 2.9 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 ORY07845.1 - 3.6e-28 98.8 42.2 4.6e-28 98.5 42.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 ORY07845.1 - 1.2e-26 93.6 52.6 1.8e-19 70.0 19.3 2.5 2 1 1 3 3 3 2 Citrate transporter Tetraspanin PF00335.20 ORY07846.1 - 5.1e-08 32.9 9.9 7.4e-08 32.4 9.9 1.3 1 0 0 1 1 1 1 Tetraspanin family Rhomboid PF01694.22 ORY07846.1 - 0.0023 18.0 5.7 0.0023 18.0 5.7 1.6 2 0 0 2 2 2 1 Rhomboid family DUF2759 PF10958.8 ORY07846.1 - 0.035 13.8 5.7 1.1 9.0 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) Bromodomain PF00439.25 ORY07847.1 - 0.0089 16.1 0.0 0.028 14.5 0.0 1.9 1 1 0 1 1 1 1 Bromodomain KleE PF17394.2 ORY07847.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein zf-C2H2_jaz PF12171.8 ORY07848.1 - 2.6e-09 37.1 2.4 2.6e-09 37.1 2.4 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY07848.1 - 1.8e-08 34.5 2.5 6.2e-08 32.8 2.5 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 ORY07848.1 - 0.0086 16.2 0.7 0.018 15.1 0.7 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 ORY07848.1 - 0.032 15.1 4.7 0.21 12.5 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-3CxxC PF13695.6 ORY07848.1 - 0.043 14.3 0.2 0.13 12.7 0.2 1.8 1 0 0 1 1 1 0 Zinc-binding domain DUF2524 PF10732.9 ORY07848.1 - 0.061 13.6 0.2 2.3 8.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) zf-C2H2_2 PF12756.7 ORY07848.1 - 0.071 13.5 3.4 1.6 9.1 0.6 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) ANAPC5 PF12862.7 ORY07848.1 - 0.076 13.1 0.6 0.26 11.4 0.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 zf-C2H2 PF00096.26 ORY07848.1 - 0.13 12.8 6.5 1.3 9.7 0.8 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type BCS1_N PF08740.11 ORY07848.1 - 0.21 11.6 1.2 9 6.2 0.5 2.4 2 0 0 2 2 2 0 BCS1 N terminal RhoGAP PF00620.27 ORY07849.1 - 5.1e-49 166.0 0.0 1.4e-48 164.6 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY07849.1 - 8.5e-08 32.7 0.1 3.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 ORY07849.1 - 8e-07 29.5 0.1 2e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PINIT PF14324.6 ORY07850.1 - 9.4e-35 120.1 0.3 2e-34 119.0 0.3 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 ORY07850.1 - 2.9e-20 71.8 6.2 2.9e-20 71.8 6.2 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY07850.1 - 5.7e-07 29.3 3.4 1.2e-06 28.2 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 ORY07850.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 ORY07850.1 - 0.98 9.5 3.6 2 8.6 2.9 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger LacAB_rpiB PF02502.18 ORY07851.1 - 3.6e-49 166.3 0.0 4.1e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2280 PF10045.9 ORY07851.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Ras PF00071.22 ORY07852.1 - 3.7e-60 202.2 0.8 6.2e-60 201.5 0.8 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY07852.1 - 6.2e-36 123.2 0.0 1.1e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY07852.1 - 3.6e-17 62.4 0.0 5.4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY07852.1 - 2e-07 30.8 0.1 3.1e-07 30.1 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY07852.1 - 2.7e-07 30.2 0.0 3.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY07852.1 - 2.5e-06 27.5 0.0 5.8e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY07852.1 - 0.00039 20.3 0.7 1.6 8.6 0.3 2.8 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY07852.1 - 0.00055 20.4 0.8 0.0011 19.4 0.8 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 ORY07852.1 - 0.0033 17.2 0.0 0.03 14.1 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 ORY07852.1 - 0.034 13.3 0.1 0.057 12.6 0.1 1.5 1 1 0 1 1 1 0 G-protein alpha subunit DUF89 PF01937.19 ORY07852.1 - 0.068 12.1 0.2 0.091 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 E7 PF00527.18 ORY07852.1 - 0.07 13.3 0.4 0.12 12.6 0.4 1.3 1 0 0 1 1 1 0 E7 protein, Early protein Rep_1 PF01446.17 ORY07852.1 - 0.083 12.3 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Replication protein AAA_26 PF13500.6 ORY07852.1 - 0.084 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_S7e PF01251.18 ORY07853.1 - 1.8e-86 288.6 2.1 2e-86 288.4 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Kri1_C PF12936.7 ORY07854.1 - 2.2e-33 114.3 2.6 2.2e-33 114.3 2.6 3.6 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 ORY07854.1 - 1.2e-29 102.8 10.3 1.2e-29 102.8 10.3 5.4 5 1 0 5 5 5 1 KRI1-like family S-antigen PF05756.11 ORY07854.1 - 0.061 13.7 0.4 0.061 13.7 0.4 4.2 4 0 0 4 4 4 0 S-antigen protein BAR_3 PF16746.5 ORY07855.1 - 9.9e-41 140.0 14.9 1.6e-26 93.5 5.8 2.2 1 1 1 2 2 2 2 BAR domain of APPL family ArfGap PF01412.18 ORY07855.1 - 8e-33 113.0 0.0 8e-33 113.0 0.0 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 ORY07855.1 - 6.9e-11 42.6 0.1 1.7e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 PH domain BAR PF03114.18 ORY07855.1 - 0.00013 21.7 4.9 0.00013 21.7 4.9 2.0 2 0 0 2 2 2 1 BAR domain APG6_N PF17675.1 ORY07855.1 - 0.0039 17.7 1.6 0.0039 17.7 1.6 2.8 2 1 1 3 3 3 1 Apg6 coiled-coil region PH_17 PF18012.1 ORY07855.1 - 0.011 15.4 0.3 0.022 14.5 0.3 1.5 1 0 0 1 1 1 0 PH domain PH_9 PF15410.6 ORY07855.1 - 0.092 13.1 0.2 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain DDHD PF02862.17 ORY07856.1 - 1.2e-35 123.8 8.5 2.9e-34 119.2 8.5 2.2 1 1 0 1 1 1 1 DDHD domain NYD-SP28 PF14772.6 ORY07856.1 - 0.048 13.7 4.4 1.8 8.6 0.6 2.7 2 0 0 2 2 2 0 Sperm tail SH3_1 PF00018.28 ORY07857.1 - 7.7e-25 86.2 0.0 3.8e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY07857.1 - 7.9e-21 73.7 0.1 1.5e-09 37.6 0.1 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 ORY07857.1 - 4.4e-15 55.1 0.0 7e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 ORY07857.1 - 6.3e-13 48.7 0.1 1.7e-12 47.3 0.1 1.7 2 0 0 2 2 2 1 PX domain PB1 PF00564.24 ORY07857.1 - 5.9e-12 45.4 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Fungal_trans PF04082.18 ORY07858.1 - 3.4e-41 141.0 0.3 5.1e-41 140.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07858.1 - 1.8e-12 47.1 11.3 2.9e-12 46.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sgf11 PF08209.11 ORY07860.1 - 1.4e-10 40.5 1.9 1.4e-10 40.5 1.9 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) TGS PF02824.21 ORY07860.1 - 0.1 12.7 0.0 11 6.1 0.0 2.4 1 1 1 2 2 2 0 TGS domain Fungal_trans PF04082.18 ORY07861.1 - 7.5e-41 139.9 3.1 1.3e-40 139.1 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07861.1 - 1.9e-12 47.1 10.1 1.9e-12 47.1 10.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY07862.1 - 1.1e-39 136.1 1.8 6.5e-39 133.6 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07863.1 - 7.5e-12 45.2 14.0 9.8e-12 44.8 14.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY07864.1 - 1.3e-40 139.2 1.3 2.7e-40 138.1 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORY07865.1 - 9.5e-40 136.3 0.3 9.5e-40 136.3 0.3 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 ORY07865.1 - 1.8e-08 33.7 1.8 2.4e-08 33.2 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORY07866.1 - 8.8e-40 136.4 0.6 8.8e-40 136.4 0.6 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY07866.1 - 5e-11 42.5 14.1 1.1e-10 41.5 14.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ORY07867.1 - 3e-60 204.4 21.7 3.7e-60 204.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY07867.1 - 2e-28 99.3 26.9 2.6e-28 99.0 25.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY07867.1 - 3.4e-06 26.6 4.0 6.8e-06 25.6 4.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORY07867.1 - 9.4e-05 21.1 9.7 9.4e-05 21.1 9.7 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein DUF417 PF04224.12 ORY07867.1 - 0.0048 16.5 0.4 0.058 13.0 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF417 OATP PF03137.20 ORY07867.1 - 0.46 8.7 10.5 0.44 8.8 3.9 2.9 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.6 ORY07867.1 - 6.9 6.3 11.8 2.5 7.7 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Lipase_3 PF01764.25 ORY07868.1 - 3.2e-18 66.0 0.0 8.4e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) TGF_beta_GS PF08515.12 ORY07868.1 - 0.018 14.6 0.1 0.055 13.0 0.1 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Hydrolase_4 PF12146.8 ORY07868.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY07868.1 - 0.18 12.4 0.4 0.35 11.4 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribonuclease_3 PF00636.26 ORY07869.1 - 5.9e-47 158.6 0.0 7.5e-22 77.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 ORY07869.1 - 2.4e-25 88.5 2.0 1e-23 83.3 0.0 4.0 5 0 0 5 5 5 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 ORY07869.1 - 2.6e-25 89.1 0.0 8.4e-14 51.8 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 ORY07869.1 - 6.6e-19 68.3 0.0 1.9e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY07869.1 - 2.5e-14 53.6 0.1 5.6e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY07869.1 - 1.8e-12 47.4 0.1 4e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAZ PF02170.22 ORY07869.1 - 1.9e-08 34.2 0.2 4.5e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.26 ORY07869.1 - 0.00055 20.6 0.0 0.049 14.4 0.0 3.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif Symplekin_C PF12295.8 ORY07869.1 - 0.054 13.6 0.3 0.67 10.0 0.0 2.4 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Prefoldin PF02996.17 ORY07870.1 - 6.6e-27 93.8 0.9 1e-26 93.2 0.9 1.4 1 0 0 1 1 1 1 Prefoldin subunit COG5 PF10392.9 ORY07870.1 - 0.0018 18.5 2.8 0.37 11.0 0.3 2.2 2 0 0 2 2 2 2 Golgi transport complex subunit 5 Trimer_CC PF08954.11 ORY07870.1 - 0.0045 16.5 1.6 0.57 9.8 0.0 2.4 2 0 0 2 2 2 1 Trimerisation motif Snapin_Pallidin PF14712.6 ORY07870.1 - 0.0047 17.3 9.7 0.28 11.6 2.8 2.3 2 0 0 2 2 2 2 Snapin/Pallidin Fzo_mitofusin PF04799.13 ORY07870.1 - 0.0066 16.0 4.6 0.7 9.4 0.5 2.1 2 0 0 2 2 2 2 fzo-like conserved region DUF5082 PF16888.5 ORY07870.1 - 0.0071 16.6 5.1 0.93 9.8 0.3 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF5082) DUF3251 PF11622.8 ORY07870.1 - 0.0076 15.9 0.7 0.015 15.0 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3251) IL6 PF00489.17 ORY07870.1 - 0.01 15.4 0.7 0.01 15.4 0.7 1.7 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Prefoldin_3 PF13758.6 ORY07870.1 - 0.012 15.7 0.1 0.035 14.2 0.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit TMF_TATA_bd PF12325.8 ORY07870.1 - 0.014 15.6 5.1 0.057 13.7 0.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 ORY07870.1 - 0.016 15.6 9.5 0.64 10.5 3.1 2.3 2 1 0 2 2 2 0 Cell division protein ZapB Fib_alpha PF08702.10 ORY07870.1 - 0.018 15.2 6.4 0.082 13.1 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 ORY07870.1 - 0.02 14.8 7.0 1.2 9.1 0.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit Filament PF00038.21 ORY07870.1 - 0.024 14.3 5.1 0.2 11.2 0.2 2.0 2 0 0 2 2 2 0 Intermediate filament protein GIT_CC PF16559.5 ORY07870.1 - 0.025 14.5 12.2 0.059 13.3 2.3 3.5 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2205 PF10224.9 ORY07870.1 - 0.033 14.2 2.6 3.3 7.8 0.5 2.5 2 1 0 2 2 2 0 Short coiled-coil protein MIS13 PF08202.11 ORY07870.1 - 0.038 13.3 4.2 0.47 9.7 0.5 2.1 2 0 0 2 2 2 0 Mis12-Mtw1 protein family DUF4164 PF13747.6 ORY07870.1 - 0.044 14.0 0.8 6.6 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CLZ PF16526.5 ORY07870.1 - 0.047 14.0 6.0 2.6 8.4 0.2 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 ORY07870.1 - 0.066 13.3 9.4 0.26 11.4 1.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 ORY07870.1 - 0.084 12.4 10.2 0.042 13.4 4.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain SYCE1 PF15233.6 ORY07870.1 - 0.093 12.8 5.3 1.3 9.1 0.5 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 ApoO PF09769.9 ORY07870.1 - 0.1 12.6 1.6 6.2 6.8 0.1 2.9 2 1 1 3 3 3 0 Apolipoprotein O FliD_N PF02465.18 ORY07870.1 - 0.13 13.0 5.3 0.24 12.1 0.2 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Uso1_p115_C PF04871.13 ORY07870.1 - 0.19 12.1 7.6 0.16 12.4 1.1 2.4 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 ORY07870.1 - 0.19 11.7 4.9 3.5 7.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) K-box PF01486.17 ORY07870.1 - 0.21 11.8 7.1 0.55 10.4 1.2 2.7 2 1 0 2 2 2 0 K-box region SlyX PF04102.12 ORY07870.1 - 0.28 11.8 5.6 1.9 9.2 0.4 2.3 2 0 0 2 2 2 0 SlyX TMPIT PF07851.13 ORY07870.1 - 0.39 9.9 4.8 0.9 8.7 0.2 2.1 1 1 0 2 2 2 0 TMPIT-like protein Sec2p PF06428.11 ORY07870.1 - 0.39 10.7 9.2 2.7 8.0 0.9 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Iron_permease PF04120.12 ORY07870.1 - 0.42 10.4 3.7 1.2 9.0 0.3 2.4 2 1 0 2 2 2 0 Low affinity iron permease FlaC_arch PF05377.11 ORY07870.1 - 0.5 10.8 4.3 7.7 7.0 0.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 ORY07870.1 - 0.54 9.1 7.5 0.42 9.5 1.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein PhaP_Bmeg PF09602.10 ORY07870.1 - 0.62 10.0 8.2 0.048 13.6 1.4 2.1 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CC2-LZ PF16516.5 ORY07870.1 - 0.63 10.4 6.8 2.1 8.8 0.8 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator WXG100 PF06013.12 ORY07870.1 - 0.68 10.2 3.9 6.8 7.0 0.6 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF745 PF05335.13 ORY07870.1 - 1.4 8.6 6.1 1.2 8.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Ribosomal_S24e PF01282.19 ORY07871.1 - 1.1e-38 131.0 1.3 1.3e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S24e DNA_methylase PF00145.17 ORY07872.1 - 3.6e-21 75.9 0.0 1.7e-17 63.8 0.0 2.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase NMT_C PF02799.15 ORY07872.1 - 0.088 12.3 0.0 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain PAXNEB PF05625.11 ORY07873.1 - 3.6e-100 335.7 0.0 4.6e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 ORY07873.1 - 0.00047 19.6 0.3 0.0027 17.1 0.0 2.0 2 0 0 2 2 2 1 KaiC IL11 PF07400.11 ORY07873.1 - 0.017 14.7 0.1 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 Interleukin 11 PPR_2 PF13041.6 ORY07874.1 - 5.6e-86 282.6 19.8 2.6e-14 53.2 0.0 12.8 4 2 9 13 13 13 10 PPR repeat family PPR PF01535.20 ORY07874.1 - 2.3e-65 212.4 12.8 1.7e-07 31.0 0.0 13.4 14 0 0 14 14 14 10 PPR repeat PPR_1 PF12854.7 ORY07874.1 - 5.1e-55 182.8 2.1 2.4e-07 30.3 0.0 11.6 11 0 0 11 11 11 9 PPR repeat PPR_3 PF13812.6 ORY07874.1 - 1.1e-47 159.9 10.9 2.1e-09 37.3 0.1 8.2 5 2 3 8 8 8 8 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY07874.1 - 1e-39 136.2 0.4 1.2e-15 57.5 0.0 4.2 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ORY07874.1 - 2.4e-05 24.7 13.0 1.5 9.2 0.2 7.1 3 2 4 7 7 7 3 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORY07874.1 - 0.00017 20.6 7.3 0.52 9.1 0.0 4.8 2 1 4 6 6 6 3 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 ORY07874.1 - 0.00023 21.7 0.9 47 5.2 0.0 7.7 7 3 5 12 12 11 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 ORY07874.1 - 0.0046 16.6 0.0 0.51 10.0 0.0 3.1 2 1 1 3 3 3 1 Rab-GTPase-TBC domain Phage_ABA_S PF18066.1 ORY07874.1 - 0.075 13.7 0.0 15 6.3 0.0 4.0 2 1 2 4 4 4 0 Phage ABA sandwich domain Vps23_core PF09454.10 ORY07874.1 - 0.081 12.9 0.0 0.58 10.2 0.0 2.5 2 0 0 2 2 2 0 Vps23 core domain MNE1 PF13762.6 ORY07874.1 - 0.21 11.6 3.5 11 6.0 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial splicing apparatus component Rhodanese PF00581.20 ORY07875.1 - 2.6e-12 47.2 0.0 4.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 ORY07876.1 - 1.2e-26 92.4 3.3 1.9e-05 25.3 0.1 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07876.1 - 8.2e-11 42.1 0.0 0.071 13.4 0.0 5.0 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 ORY07876.1 - 0.00039 20.3 0.1 0.00072 19.4 0.1 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 ORY07876.1 - 0.0034 16.1 1.1 0.023 13.4 0.7 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY07876.1 - 0.023 14.0 0.2 0.29 10.4 0.1 2.7 2 1 0 2 2 2 0 WD40-like domain Coatomer_WDAD PF04053.14 ORY07876.1 - 0.078 12.0 0.1 0.94 8.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region C2 PF00168.30 ORY07877.1 - 9.5e-17 61.2 0.0 2.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 ORY07877.1 - 9.9e-14 51.7 0.2 1.5e-05 25.2 0.4 3.2 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 ORY07877.1 - 3.2e-05 22.7 0.1 6.7e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) PAZ_siRNAbind PF12212.8 ORY07877.1 - 0.16 11.8 1.0 3 7.7 0.0 2.9 2 1 1 3 3 3 0 PAZ domain Snurportin1 PF11538.8 ORY07878.1 - 0.014 15.5 0.4 0.035 14.3 0.4 1.6 1 0 0 1 1 1 0 Snurportin1 mRNA_cap_enzyme PF01331.19 ORY07878.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Vps39_2 PF10367.9 ORY07880.1 - 8.1e-19 68.1 0.2 3.8e-18 65.9 0.3 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ORY07880.1 - 1.4e-16 60.7 0.1 7.3e-15 55.2 0.1 3.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 ORY07880.1 - 2.9e-16 59.9 0.0 4.8e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain DNA_pol_A_exo1 PF01612.20 ORY07881.1 - 2.8e-19 69.5 0.0 4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease YIF1 PF03878.15 ORY07882.1 - 1.5e-89 299.7 1.8 1.7e-89 299.5 1.8 1.0 1 0 0 1 1 1 1 YIF1 NDUF_C2 PF06374.11 ORY07883.1 - 0.02 15.1 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) WD40 PF00400.32 ORY07884.1 - 1.2e-28 98.7 3.3 2.2e-09 37.7 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY07884.1 - 1.7e-11 44.3 0.1 0.00034 20.8 0.1 4.6 4 1 1 5 5 4 2 Anaphase-promoting complex subunit 4 WD40 domain Speriolin_N PF15058.6 ORY07884.1 - 0.006 16.7 0.2 0.01 15.9 0.2 1.3 1 0 0 1 1 1 1 Speriolin N terminus Csm1_N PF18504.1 ORY07884.1 - 0.0073 16.6 1.9 0.0073 16.6 1.9 1.9 2 0 0 2 2 2 1 Csm1 N-terminal domain Nup160 PF11715.8 ORY07884.1 - 0.01 14.5 0.4 1.3 7.6 0.0 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Shugoshin_N PF07558.11 ORY07884.1 - 0.048 13.5 2.5 0.11 12.4 2.5 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 ORY07884.1 - 0.058 13.5 3.6 0.22 11.7 3.6 2.0 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 ORY07884.1 - 0.13 13.0 3.1 11 6.8 3.2 2.9 2 1 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 ORY07884.1 - 0.4 10.5 3.5 0.91 9.3 3.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Uds1 PF15456.6 ORY07884.1 - 0.86 9.8 8.6 1.5 9.0 8.6 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Cnn_1N PF07989.11 ORY07884.1 - 0.99 9.6 8.6 0.15 12.3 3.1 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 ORY07884.1 - 3.4 7.8 7.7 1.1 9.4 4.0 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Peptidase_S8 PF00082.22 ORY07885.1 - 1.1e-36 126.7 7.6 3e-36 125.2 7.6 1.6 1 1 0 1 1 1 1 Subtilase family Peptidase_M57 PF12388.8 ORY07885.1 - 0.081 12.5 0.5 0.15 11.6 0.5 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Inhibitor_I9 PF05922.16 ORY07885.1 - 0.12 13.1 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF2478 PF10649.9 ORY07885.1 - 0.17 11.5 0.2 2.1 7.9 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2478) SNARE_assoc PF09335.11 ORY07886.1 - 9.3e-17 61.6 5.1 9.3e-17 61.6 5.1 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein EptA_B_N PF08019.12 ORY07886.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.6 4 0 0 4 4 4 0 Phosphoethanolamine transferase EptA/EptB Carn_acyltransf PF00755.20 ORY07887.1 - 1.5e-206 687.5 0.1 1.8e-206 687.3 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SAS-6_N PF16531.5 ORY07887.1 - 0.13 12.9 0.1 2.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Centriolar protein SAS N-terminal COQ7 PF03232.13 ORY07888.1 - 1.3e-77 259.5 0.1 1.6e-77 259.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin PF00210.24 ORY07888.1 - 0.012 15.6 0.9 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 Ferritin-like domain Rubrerythrin PF02915.17 ORY07888.1 - 0.031 14.7 0.0 0.089 13.2 0.0 2.0 1 1 0 1 1 1 0 Rubrerythrin Patched PF02460.18 ORY07889.1 - 1.9e-85 287.6 13.0 4.1e-53 180.6 0.2 2.1 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 ORY07889.1 - 1.5e-74 250.7 7.5 2.5e-74 249.9 7.5 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 ORY07889.1 - 1.3e-51 174.5 8.9 1.3e-51 174.5 8.9 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 ORY07889.1 - 4.1e-06 26.0 3.0 4.1e-06 26.0 3.0 2.4 2 0 0 2 2 2 1 MMPL family Folate_rec PF03024.14 ORY07889.1 - 0.0081 16.0 2.0 0.021 14.7 2.0 1.6 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 ORY07889.1 - 0.68 7.5 18.6 0.017 12.8 12.2 1.4 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family ADH_zinc_N PF00107.26 ORY07957.1 - 2.2e-15 56.8 0.0 4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY07957.1 - 5.7e-06 25.8 0.0 9.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 ORY07957.1 - 2e-05 24.5 1.9 2.6e-05 24.0 0.3 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 ORY07957.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ORY07957.1 - 3.3e-05 24.9 0.0 6.7e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 ORY07957.1 - 0.037 13.7 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase EIF_2_alpha PF07541.12 ORY07957.1 - 0.043 13.9 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit 3HCDH_N PF02737.18 ORY07957.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1325 PF07039.11 ORY07958.1 - 6.6e-35 120.1 0.6 1.2e-34 119.2 0.6 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 ORY07958.1 - 0.0096 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 ORY07958.1 - 0.028 14.9 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 Agenet domain RhoGEF PF00621.20 ORY07959.1 - 3.4e-34 118.7 5.1 6.9e-34 117.7 5.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 ORY07959.1 - 0.00082 19.9 0.2 0.0056 17.2 0.1 2.5 2 0 0 2 2 2 1 PH domain PEPCK_ATP PF01293.20 ORY07960.1 - 7.5e-230 763.4 0.0 8.7e-230 763.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORY07961.1 - 2e-214 712.5 0.0 2.3e-213 709.1 0.0 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORY07962.1 - 7.5e-230 763.4 0.0 8.7e-230 763.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.20 ORY07963.1 - 1.2e-179 597.9 0.1 3.1e-100 336.1 0.0 3.0 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase Aa_trans PF01490.18 ORY07964.1 - 1.3e-58 198.6 40.9 1.6e-58 198.3 40.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY07964.1 - 5e-05 22.3 29.0 5e-05 22.3 29.0 2.5 1 1 1 2 2 2 1 Amino acid permease EBP PF05241.12 ORY07965.1 - 7.1e-56 188.5 6.4 8.5e-56 188.2 6.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein Pkinase PF00069.25 ORY07966.1 - 7.4e-73 245.1 0.0 8.4e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY07966.1 - 7.7e-56 189.2 0.0 9.4e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY07966.1 - 5.4e-05 22.9 0.1 0.00015 21.4 0.1 1.7 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 ORY07966.1 - 8.3e-05 22.2 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 ORY07966.1 - 0.0017 17.5 0.6 0.0026 16.9 0.1 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 ORY07966.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.8 2 1 0 2 2 2 0 Kinase-like Septin PF00735.18 ORY07967.1 - 3.4e-113 377.6 0.8 4.6e-113 377.2 0.8 1.1 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 ORY07967.1 - 2.5e-09 37.0 1.2 1.8e-07 30.9 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY07967.1 - 8.9e-09 35.4 0.1 2.2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY07967.1 - 2.3e-07 30.9 1.4 3.1e-06 27.2 0.9 2.3 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ORY07967.1 - 4.3e-05 23.7 0.5 9.6e-05 22.6 0.5 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 ORY07967.1 - 0.00013 21.4 0.1 0.00013 21.4 0.1 1.8 2 0 0 2 2 2 1 AIG1 family Pox_A32 PF04665.12 ORY07967.1 - 0.00016 21.3 0.1 0.00037 20.0 0.1 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein IIGP PF05049.13 ORY07967.1 - 0.00036 19.7 0.1 0.00098 18.3 0.0 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.12 ORY07967.1 - 0.00065 19.1 0.1 0.0015 17.9 0.1 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY07967.1 - 0.0014 18.2 1.4 0.0062 16.2 0.3 2.4 2 1 1 3 3 3 1 Ras family AAA_22 PF13401.6 ORY07967.1 - 0.0019 18.5 0.3 0.0061 16.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY07967.1 - 0.01 16.4 0.2 0.025 15.1 0.0 1.7 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.22 ORY07967.1 - 0.016 15.6 0.2 0.054 13.9 0.1 2.0 2 1 0 2 2 1 0 RNA helicase AAA_16 PF13191.6 ORY07967.1 - 0.017 15.5 0.3 0.055 13.8 0.0 2.0 3 0 0 3 3 2 0 AAA ATPase domain AAA_24 PF13479.6 ORY07967.1 - 0.018 14.8 0.8 0.044 13.5 0.6 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 ORY07967.1 - 0.022 14.0 1.1 0.089 11.9 0.6 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.26 ORY07967.1 - 0.024 14.3 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 ORY07967.1 - 0.031 14.0 1.3 0.4 10.4 0.4 2.4 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 ORY07967.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 ORY07967.1 - 0.05 13.1 0.2 0.088 12.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 ORY07967.1 - 0.072 12.6 0.7 0.78 9.2 0.7 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 ORY07967.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 ORY07967.1 - 0.077 12.0 1.1 0.19 10.8 1.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 ORY07967.1 - 0.14 12.6 10.3 16 5.9 10.3 2.3 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY07967.1 - 0.45 10.6 5.5 3 7.9 0.1 2.7 2 1 1 3 3 2 0 Dynamin family CortBP2 PF09727.9 ORY07967.1 - 1.2 9.0 11.9 0.13 12.2 2.3 2.6 2 1 0 2 2 2 0 Cortactin-binding protein-2 FOXP-CC PF16159.5 ORY07967.1 - 3 8.5 5.1 0.86 10.3 1.4 2.1 2 1 0 2 2 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY07968.1 - 0.011 16.1 0.3 0.055 13.9 0.3 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORY07968.1 - 0.026 14.7 3.5 0.027 14.6 0.3 2.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORY07968.1 - 1.9 9.5 5.2 1.7 9.7 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M1 PF01433.20 ORY07969.1 - 6e-45 153.5 0.1 8.8e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORY07969.1 - 2.9e-41 140.1 0.0 5.3e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORY07969.1 - 1.6e-30 106.7 0.0 2.4e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3509 PF12021.8 ORY07969.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Nas2_N PF18265.1 ORY07970.1 - 1e-27 95.8 0.3 1.5e-27 95.3 0.3 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 ORY07970.1 - 7.3e-09 35.4 0.1 1.2e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 ORY07970.1 - 1.4e-07 31.7 0.1 3.9e-07 30.3 0.0 1.6 1 1 1 2 2 2 1 PDZ domain PDZ PF00595.24 ORY07970.1 - 1e-06 29.0 0.1 1.9e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ORY07970.1 - 1e-06 29.1 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Myb_DNA-binding PF00249.31 ORY07971.1 - 1.4e-57 191.7 34.1 2.9e-14 53.0 0.1 5.8 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY07971.1 - 7.9e-50 167.0 18.3 7.7e-14 51.7 0.0 6.1 2 2 3 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 ORY07971.1 - 2e-10 40.7 0.1 0.065 13.3 0.1 4.5 1 1 2 4 4 4 3 SLIDE Rap1_C PF11626.8 ORY07971.1 - 5.3e-06 26.4 6.7 0.33 11.1 0.1 4.2 2 1 2 4 4 4 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 ORY07971.1 - 0.011 15.9 6.4 5.2 7.3 0.0 4.7 2 2 1 5 5 5 0 SANT/Myb-like domain of DAMP1 DUF1400 PF07176.11 ORY07971.1 - 0.17 12.2 0.1 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) JmjC PF02373.22 ORY07972.1 - 2.5e-14 53.7 0.1 5.1e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 ORY07972.1 - 0.00023 20.9 0.0 0.0054 16.5 0.0 2.2 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 ORY07972.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 ORY07972.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain LRR_8 PF13855.6 ORY07973.1 - 5.6e-24 83.7 24.3 1.4e-09 37.5 3.7 4.3 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY07973.1 - 7.4e-23 80.2 23.0 1.3e-05 25.5 0.7 5.4 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY07973.1 - 1.2e-14 52.6 26.1 0.39 11.5 0.0 9.9 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY07973.1 - 1.8e-06 27.5 31.9 0.3 11.3 0.2 9.0 9 0 0 9 9 9 6 Leucine Rich repeat LRR_2 PF07723.13 ORY07973.1 - 2.5e-06 27.9 5.2 6.5 7.6 0.0 6.2 7 0 0 7 7 7 3 Leucine Rich Repeat Transposase_31 PF04754.12 ORY07973.1 - 0.22 11.1 0.0 1.8 8.1 0.0 2.4 3 0 0 3 3 3 0 Putative transposase, YhgA-like Lon_C PF05362.13 ORY07974.1 - 2.2e-80 269.0 1.2 3.8e-80 268.2 1.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ORY07974.1 - 1.2e-22 80.8 0.0 4.4e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY07974.1 - 8.7e-11 42.0 0.0 2.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORY07974.1 - 6.6e-07 29.2 0.1 2.6e-06 27.3 0.0 2.1 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 ORY07974.1 - 1.6e-06 28.3 0.0 1.3e-05 25.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 ORY07974.1 - 1.3e-05 24.4 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 ORY07974.1 - 3e-05 24.3 0.0 0.00085 19.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY07974.1 - 3.6e-05 23.6 0.0 0.00079 19.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 ORY07974.1 - 5.9e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 ORY07974.1 - 0.00015 21.7 2.3 0.00037 20.4 0.1 2.3 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain RsgA_GTPase PF03193.16 ORY07974.1 - 0.00026 20.9 0.0 0.00081 19.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORY07974.1 - 0.00027 21.4 0.5 0.0039 17.6 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 ORY07974.1 - 0.002 17.9 0.0 0.0075 16.0 0.0 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORY07974.1 - 0.0086 16.6 1.7 0.062 13.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain Birna_VP4 PF01768.16 ORY07974.1 - 0.018 14.9 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 Birnavirus VP4 protein NTPase_1 PF03266.15 ORY07974.1 - 0.039 13.9 0.1 0.65 9.9 0.1 2.6 1 1 1 2 2 2 0 NTPase NB-ARC PF00931.22 ORY07974.1 - 0.063 12.4 1.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 ORY07974.1 - 0.11 12.9 0.3 0.29 11.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 ORY07974.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY07974.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY07974.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 ORY07974.1 - 0.14 12.3 0.4 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain WSC PF01822.19 ORY07975.1 - 8.6e-16 57.9 3.2 1.4e-15 57.2 3.2 1.4 1 0 0 1 1 1 1 WSC domain SerH PF06873.11 ORY07975.1 - 0.011 14.5 2.1 0.015 14.1 2.1 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH WD40 PF00400.32 ORY07976.1 - 1.4e-17 63.7 11.6 0.0027 18.5 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 ORY07976.1 - 1.4e-07 30.4 2.1 0.025 13.1 0.0 3.8 3 1 1 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 ORY07976.1 - 0.00043 20.5 0.0 0.18 12.1 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY07976.1 - 0.0078 14.9 0.6 0.88 8.1 0.1 3.0 3 1 0 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ORY07976.1 - 0.012 15.6 0.0 2.1 8.5 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 ORY07976.1 - 0.029 14.9 0.0 2.3 8.8 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Ribosomal_L17 PF01196.19 ORY07977.1 - 9.7e-31 106.5 2.2 1.1e-30 106.4 0.1 2.0 2 1 0 2 2 2 1 Ribosomal protein L17 YscO PF07321.12 ORY07977.1 - 0.021 14.8 0.5 0.021 14.8 0.5 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Codanin-1_C PF15296.6 ORY07977.1 - 0.05 13.7 1.6 0.061 13.4 0.2 1.8 2 0 0 2 2 2 0 Codanin-1 C-terminus ThiF PF00899.21 ORY07978.1 - 9.8e-65 218.3 0.0 1.4e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 ORY07978.1 - 2e-29 101.5 1.2 3.2e-29 100.9 1.2 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 ORY07978.1 - 0.0015 18.6 0.1 0.0038 17.3 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 ORY07978.1 - 0.038 14.1 1.3 0.088 13.0 1.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PglD_N PF17836.1 ORY07978.1 - 0.096 13.3 0.1 0.37 11.5 0.0 2.0 2 0 0 2 2 2 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 ORY07978.1 - 0.13 12.2 0.4 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 ORY07978.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Choline_kinase PF01633.20 ORY07980.1 - 7.4e-65 218.5 0.0 1.1e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 ORY07980.1 - 3.2e-13 50.2 0.0 4.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY07980.1 - 0.13 11.2 0.6 0.21 10.5 0.6 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HLH PF00010.26 ORY07981.1 - 1.2e-13 50.7 1.7 2.9e-13 49.6 1.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFMR_assoc PF16596.5 ORY07981.1 - 0.093 13.2 2.5 0.15 12.6 2.5 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR DUF4298 PF14131.6 ORY07981.1 - 0.8 9.7 5.2 0.42 10.6 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) HrpA_pilin PF09589.10 ORY07981.1 - 1.2 9.9 8.8 0.49 11.1 0.2 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein YabA PF06156.13 ORY07981.1 - 1.3 9.7 12.4 0.13 13.0 4.4 2.3 1 1 0 2 2 2 0 Initiation control protein YabA PGK PF00162.19 ORY07982.1 - 3.6e-148 493.5 1.1 4.1e-148 493.3 1.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 ORY07982.1 - 0.002 18.1 0.1 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 PA domain Homeodomain PF00046.29 ORY07983.1 - 6.5e-15 54.7 1.4 7.5e-15 54.5 0.7 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY07983.1 - 1.4e-11 44.1 0.1 2.5e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 ORY07983.1 - 0.0068 15.8 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez BLM10_N PF16547.5 ORY07983.1 - 0.096 13.0 0.9 0.25 11.7 0.2 1.9 1 1 1 2 2 2 0 Proteasome-substrate-size regulator, N-terminal Ribul_P_3_epim PF00834.19 ORY07984.1 - 8.7e-76 253.7 0.2 1e-75 253.5 0.2 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 ORY07984.1 - 0.0029 17.4 0.2 0.013 15.3 0.1 2.0 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.17 ORY07984.1 - 0.019 14.4 0.1 0.03 13.8 0.1 1.3 1 1 0 1 1 1 0 PcrB family LysM PF01476.20 ORY07985.1 - 3.1e-07 30.3 0.0 5.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain IER PF05760.12 ORY07985.1 - 0.064 13.5 0.5 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 Immediate early response protein (IER) RGS PF00615.19 ORY07986.1 - 1.7e-12 47.6 0.6 2.7e-12 47.0 0.6 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RhoGAP PF00620.27 ORY07989.1 - 9.4e-44 148.9 0.1 3.1e-43 147.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 ORY07989.1 - 3.9e-18 65.9 0.0 1.1e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PX PF00787.24 ORY07989.1 - 8.5e-10 38.6 0.1 2e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 ORY07989.1 - 0.002 18.4 0.1 0.008 16.4 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 ORY07989.1 - 0.053 13.8 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain CX9C PF16860.5 ORY07990.1 - 1.3e-05 25.1 11.0 0.0048 16.9 4.0 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 ORY07990.1 - 0.00018 21.6 4.7 0.00018 21.6 4.7 2.6 2 1 0 2 2 2 2 CHCH domain Pet191_N PF10203.9 ORY07990.1 - 9.4 6.6 12.4 28 5.1 0.3 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 ELL PF10390.9 ORY07991.1 - 1.4e-11 44.4 1.4 1.4e-11 44.4 1.4 2.3 3 0 0 3 3 3 1 RNA polymerase II elongation factor ELL DUF4239 PF14023.6 ORY07991.1 - 0.68 9.6 2.6 0.52 10.0 0.3 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) RasGEF PF00617.19 ORY07992.1 - 2.9e-57 193.7 2.3 5.2e-56 189.6 0.8 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORY07992.1 - 2.6e-25 88.7 0.3 1.2e-24 86.6 0.3 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif AROS PF15684.5 ORY07992.1 - 0.051 14.1 2.0 0.38 11.3 0.0 2.8 3 0 0 3 3 3 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Nup96 PF12110.8 ORY07993.1 - 9.1e-87 290.9 0.0 1.8e-86 289.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 ORY07993.1 - 1.6e-53 180.9 0.1 4.3e-53 179.4 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 ORY07993.1 - 0.0018 19.1 31.8 0.0018 19.1 31.8 10.0 3 2 3 6 6 6 2 Nucleoporin FG repeat region Aldo_ket_red PF00248.21 ORY07995.1 - 7e-08 32.0 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family RPAP1_N PF08621.10 ORY07995.1 - 0.15 11.8 0.2 0.37 10.6 0.2 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Bromodomain PF00439.25 ORY07996.1 - 2.7e-46 155.5 1.7 4e-23 81.3 0.1 2.8 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 ORY07996.1 - 1.6e-23 82.7 0.4 5e-23 81.1 0.4 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DASH_Hsk3 PF08227.11 ORY07996.1 - 0.11 12.9 0.3 0.37 11.2 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Recep_L_domain PF01030.24 ORY07997.1 - 4.4e-10 39.7 15.3 0.00043 20.4 0.3 4.4 1 1 2 4 4 4 4 Receptor L domain ARS2 PF04959.13 ORY07998.1 - 0.00011 22.7 4.0 0.00011 22.6 1.3 2.0 1 1 0 2 2 2 1 Arsenite-resistance protein 2 zf-C2H2_aberr PF17017.5 ORY07998.1 - 0.016 15.3 7.6 2.6 8.1 5.2 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger Penicil_amidase PF01804.18 ORY07998.1 - 0.031 13.3 0.1 0.037 13.0 0.1 1.1 1 0 0 1 1 1 0 Penicillin amidase zf-C2H2 PF00096.26 ORY07998.1 - 0.042 14.3 3.4 0.042 14.3 3.4 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY07998.1 - 0.087 13.7 4.9 0.087 13.7 4.9 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger Ogr_Delta PF04606.12 ORY07998.1 - 0.1 12.6 3.8 1.1 9.2 0.5 2.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF2457 PF10446.9 ORY07998.1 - 2.6 7.1 13.0 3.2 6.8 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HECT PF00632.25 ORY07999.1 - 1.7e-72 244.5 0.0 2.8e-72 243.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Hydrolase_4 PF12146.8 ORY07999.1 - 0.18 11.0 0.0 0.87 8.8 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Ydc2-catalyt PF09159.10 ORY08000.1 - 9.8e-17 61.6 9.3 2.4e-14 53.8 5.0 3.7 2 1 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 ORY08000.1 - 6.6e-08 32.1 1.1 3.7e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.13 ORY08000.1 - 0.0027 17.8 0.5 1.1 9.3 0.0 2.5 1 1 1 2 2 2 2 Poxvirus A22 protein DUF3348 PF11828.8 ORY08000.1 - 0.0072 16.0 0.5 0.013 15.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) PRP9_N PF16958.5 ORY08000.1 - 0.05 13.6 0.7 0.12 12.4 0.4 1.7 1 1 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus GST_N_3 PF13417.6 ORY08001.1 - 6.5e-19 68.1 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY08001.1 - 2.6e-14 53.3 0.0 5.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY08001.1 - 1.1e-11 44.9 0.0 2.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY08001.1 - 7.9e-10 38.6 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY08001.1 - 1.9e-07 31.6 0.0 3.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY08001.1 - 0.0016 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L5_C PF00673.21 ORY08002.1 - 1.2e-22 79.9 0.0 1.7e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY08002.1 - 3e-22 78.7 0.0 1.9e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 ORY08002.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Plant_NMP1 PF06694.11 ORY08003.1 - 2.9e-07 29.9 2.4 4.9e-07 29.1 0.6 1.9 2 0 0 2 2 2 1 Plant nuclear matrix protein 1 (NMP1) Ran-binding PF05508.11 ORY08003.1 - 0.0017 17.4 0.5 0.0029 16.6 0.5 1.3 1 0 0 1 1 1 1 RanGTP-binding protein XPC-binding PF09280.11 ORY08003.1 - 0.11 12.2 0.9 21 5.0 0.0 2.7 2 0 0 2 2 2 0 XPC-binding domain FAT PF02259.23 ORY08003.1 - 0.13 11.5 4.3 0.28 10.4 4.3 1.5 1 1 0 1 1 1 0 FAT domain SAP PF02037.27 ORY08003.1 - 0.32 10.8 1.7 2.2 8.1 0.1 2.7 2 0 0 2 2 2 0 SAP domain Syntaxin_2 PF14523.6 ORY08003.1 - 2.4 8.6 6.9 4.9 7.6 1.1 2.7 2 1 0 2 2 2 0 Syntaxin-like protein DUF4298 PF14131.6 ORY08003.1 - 2.4 8.2 7.6 3.5 7.6 0.5 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) PAP2 PF01569.21 ORY08004.1 - 6.3e-14 51.9 6.9 6.3e-14 51.9 6.9 2.4 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 ORY08004.1 - 0.0021 18.2 0.1 0.25 11.5 0.0 2.3 1 1 1 2 2 2 2 Divergent PAP2 family UPF0220 PF05255.11 ORY08004.1 - 0.018 14.6 0.5 0.051 13.1 0.1 1.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0220) WD40 PF00400.32 ORY08005.1 - 4.5e-43 144.4 24.3 6.7e-07 29.9 1.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY08005.1 - 1.2e-20 73.6 7.9 6.8e-06 26.3 0.0 6.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY08005.1 - 1.7e-09 37.9 0.6 0.00012 22.0 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY08005.1 - 7.1e-07 28.8 0.1 0.19 11.0 0.0 3.6 2 1 2 4 4 4 4 WD40-like domain Cytochrom_D1 PF02239.16 ORY08005.1 - 2.3e-06 26.4 1.1 0.076 11.5 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 ORY08005.1 - 3.4e-06 26.0 4.1 0.034 12.8 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY08005.1 - 0.00022 20.3 0.9 5.6 5.8 0.0 4.3 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 ORY08005.1 - 0.00053 19.5 0.1 0.06 12.8 0.0 2.7 1 1 0 2 2 2 1 Domain of unknown function (DUF5046) PQQ PF01011.21 ORY08005.1 - 0.0006 19.6 1.1 0.24 11.4 0.0 3.8 4 0 0 4 4 4 1 PQQ enzyme repeat PALB2_WD40 PF16756.5 ORY08005.1 - 0.0014 17.6 7.6 0.92 8.4 0.5 4.1 1 1 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 ORY08005.1 - 0.0023 16.3 0.0 0.011 14.1 0.0 2.0 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORY08005.1 - 0.021 13.6 4.0 12 4.5 0.3 3.9 1 1 2 4 4 4 0 Nup133 N terminal like PQQ_3 PF13570.6 ORY08005.1 - 0.027 15.0 0.3 0.78 10.3 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain DUF2415 PF10313.9 ORY08005.1 - 0.073 13.0 0.3 3.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) DHFR_2 PF06442.11 ORY08005.1 - 0.15 11.9 0.8 3.6 7.5 0.0 2.9 3 0 0 3 3 3 0 R67 dihydrofolate reductase Tubulin PF00091.25 ORY08006.1 - 4.3e-71 239.2 0.0 9.3e-71 238.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY08006.1 - 2.9e-42 143.8 0.1 5.3e-42 142.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY08006.1 - 4.9e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY08006.1 - 0.00046 19.9 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORY08006.1 - 0.038 13.2 0.1 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Tubulin like AAA_2 PF07724.14 ORY08007.1 - 1.6e-41 142.2 0.0 3.3e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ORY08007.1 - 4.9e-16 59.4 0.0 9.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY08007.1 - 4.5e-15 55.5 0.1 1.1e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY08007.1 - 1.9e-06 27.9 0.0 5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY08007.1 - 3e-06 26.8 0.3 0.0011 18.4 0.1 3.2 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ORY08007.1 - 5.5e-06 26.2 1.0 0.00017 21.3 0.2 3.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ORY08007.1 - 0.00011 22.0 0.1 0.077 12.7 0.0 2.5 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ORY08007.1 - 0.0014 18.9 0.6 0.03 14.6 0.6 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY08007.1 - 0.0017 18.8 0.7 0.011 16.2 0.1 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 ORY08007.1 - 0.0027 17.4 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY08007.1 - 0.0042 17.1 0.1 0.02 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 ORY08007.1 - 0.0073 16.4 0.1 0.029 14.5 0.0 2.0 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORY08007.1 - 0.0074 16.0 0.0 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein MCM PF00493.23 ORY08007.1 - 0.0099 15.0 0.1 0.032 13.3 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain ABC_tran PF00005.27 ORY08007.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 ORY08007.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 ORY08007.1 - 0.012 15.2 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ORY08007.1 - 0.021 14.7 0.0 0.096 12.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 ORY08007.1 - 0.035 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORY08007.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY08007.1 - 0.085 13.0 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 ORY08007.1 - 0.11 11.7 0.0 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 DEAD PF00270.29 ORY08007.1 - 0.12 12.1 0.3 0.58 9.9 0.0 2.0 2 1 0 3 3 3 0 DEAD/DEAH box helicase TIP49 PF06068.13 ORY08007.1 - 0.13 11.5 0.0 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 ORY08007.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_cyclohydro2 PF00925.20 ORY08008.1 - 3.8e-69 231.4 0.0 5.3e-69 231.0 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Pam16 PF03656.13 ORY08009.1 - 0.00078 19.5 0.0 0.00078 19.5 0.0 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 ORY08009.1 - 0.0034 17.5 0.0 0.0083 16.2 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Ribosomal_L24e PF01246.20 ORY08010.1 - 2e-31 108.0 9.4 3.7e-31 107.1 9.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Aminotran_5 PF00266.19 ORY08011.1 - 2.1e-93 313.3 0.0 2.4e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY08011.1 - 3.6e-08 33.0 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY08011.1 - 3.6e-05 23.3 0.1 0.0001 21.7 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 ORY08011.1 - 0.0015 17.3 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 ORY08011.1 - 0.0083 14.7 0.1 0.013 14.1 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AAA PF00004.29 ORY08012.1 - 1.5e-41 141.9 0.1 3.9e-41 140.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY08012.1 - 1.6e-18 66.4 0.1 3e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY08012.1 - 2.4e-09 36.9 0.6 6.5e-09 35.5 0.6 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY08012.1 - 7.4e-06 26.5 0.3 0.0081 16.6 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 ORY08012.1 - 7.5e-05 22.7 2.1 0.00023 21.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY08012.1 - 0.00018 21.3 0.0 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY08012.1 - 0.00042 20.5 0.0 0.0027 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY08012.1 - 0.00085 19.6 0.5 0.037 14.3 0.3 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 ORY08012.1 - 0.0016 18.0 0.9 0.023 14.2 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.13 ORY08012.1 - 0.0016 17.6 0.0 0.0034 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ORY08012.1 - 0.004 16.6 0.1 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY08012.1 - 0.006 16.7 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY08012.1 - 0.0099 16.4 0.2 0.074 13.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY08012.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 ORY08012.1 - 0.032 14.0 1.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY08012.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Sipho_Gp157 PF05565.11 ORY08012.1 - 0.043 13.8 4.4 0.16 12.0 4.4 2.0 1 0 0 1 1 1 0 Siphovirus Gp157 AAA_14 PF13173.6 ORY08012.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY08012.1 - 0.084 12.2 2.2 0.12 11.7 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 ORY08012.1 - 0.084 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY08012.1 - 0.09 13.2 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ORY08012.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORY08012.1 - 0.16 11.7 2.2 0.25 11.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain FlxA PF14282.6 ORY08012.1 - 6.9 6.7 7.4 19 5.3 7.2 1.8 2 0 0 2 2 2 0 FlxA-like protein SpoU_methylase PF00588.19 ORY08013.1 - 8e-31 107.1 0.0 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ORY08013.1 - 2.9e-12 46.7 0.0 6.1e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding YebG PF07130.12 ORY08013.1 - 0.056 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 YebG protein DNA_meth_N PF18284.1 ORY08013.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA methylase N-terminal domain EMP24_GP25L PF01105.24 ORY08014.1 - 5.2e-50 169.9 0.8 5.7e-50 169.8 0.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ComJ PF11033.8 ORY08014.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Competence protein J (ComJ) Ribosomal_S10 PF00338.22 ORY08015.1 - 3.6e-29 100.9 0.0 5.4e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e KH_1 PF00013.29 ORY08016.1 - 3.4e-09 36.4 0.0 8.4e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 KH domain DUF1350 PF07082.11 ORY08016.1 - 0.05 12.9 0.0 0.38 10.0 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1350) Glyco_transf_41 PF13844.6 ORY08017.1 - 6.2e-116 387.6 1.0 2e-58 198.0 0.0 3.7 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 ORY08017.1 - 8.3e-24 82.4 0.0 5.2e-06 26.1 0.0 6.1 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY08017.1 - 3.4e-17 61.1 0.0 0.00091 19.2 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY08017.1 - 1.3e-16 59.9 2.6 0.0002 21.1 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY08017.1 - 5.6e-15 54.6 1.9 0.031 14.7 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY08017.1 - 1.8e-14 52.7 0.0 0.00014 21.8 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY08017.1 - 3.4e-14 52.2 0.0 0.00012 21.6 0.0 5.8 3 2 3 6 6 6 3 TPR repeat TPR_12 PF13424.6 ORY08017.1 - 1.3e-13 51.0 0.0 0.0013 19.0 0.0 4.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY08017.1 - 8.2e-08 32.8 0.0 0.00017 22.1 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY08017.1 - 5.7e-07 29.8 0.0 0.037 14.8 0.0 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY08017.1 - 5.9e-06 26.0 0.1 0.02 14.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY08017.1 - 2.6e-05 24.7 0.0 0.15 12.6 0.0 4.8 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY08017.1 - 0.0028 17.7 0.0 0.33 11.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 ORY08017.1 - 0.084 13.3 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Diphthami_syn_2 PF01902.17 ORY08019.1 - 8e-28 97.4 0.0 9.2e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 ORY08019.1 - 0.003 17.1 0.0 0.0074 15.8 0.0 1.7 1 1 1 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 ORY08019.1 - 0.019 14.7 0.0 5.2 6.8 0.0 2.2 1 1 1 2 2 2 0 PP-loop family DUF3798 PF12683.7 ORY08019.1 - 0.051 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Myosin_head PF00063.21 ORY08020.1 - 3.2e-52 177.7 0.2 3.8e-52 177.4 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 ORY08021.1 - 4.8e-237 787.7 0.8 7e-237 787.2 0.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY08021.1 - 1.4e-35 122.7 0.1 1.8e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY08021.1 - 4.4e-17 61.7 0.2 2.8e-16 59.2 0.4 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORY08021.1 - 3.6e-12 46.6 1.8 3.6e-12 46.6 1.8 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY08021.1 - 5.9e-12 46.0 0.0 2e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORY08021.1 - 9.8e-11 41.6 4.7 6.6e-08 32.6 0.1 3.9 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY08021.1 - 0.0013 18.6 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY08021.1 - 0.1 12.1 0.1 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 PsbT PF01405.17 ORY08021.1 - 5.5 6.9 7.1 14 5.6 7.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre T protein DUF3506 PF12014.8 ORY08022.1 - 7.7e-22 77.8 0.0 4.9e-20 72.0 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 ORY08022.1 - 5.9e-06 26.1 0.0 2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY08022.1 - 4.8e-05 23.1 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY08022.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box PRANC PF09372.10 ORY08022.1 - 0.079 13.3 0.2 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 PRANC domain DUF4011 PF13195.6 ORY08023.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF5462 PF17547.2 ORY08023.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5462) ADH_N PF08240.12 ORY08091.1 - 6.7e-34 116.1 2.3 1.2e-33 115.2 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY08091.1 - 3.4e-06 27.1 0.1 6e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY08091.1 - 0.03 13.8 0.4 0.046 13.2 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ORY08091.1 - 0.069 12.5 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY08091.1 - 0.072 12.4 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 ORY08092.1 - 3.1e-36 124.6 1.4 5.3e-36 123.8 1.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORY08092.1 - 4.5e-21 75.5 0.0 7.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ApbA PF02558.16 ORY08092.1 - 0.00032 20.4 1.5 0.0021 17.7 0.7 2.4 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORY08092.1 - 0.0085 16.7 0.7 0.034 14.7 0.3 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORY08092.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY08092.1 - 0.044 13.7 1.4 0.052 13.4 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY08092.1 - 0.07 13.4 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ORY08092.1 - 0.08 12.5 1.0 0.18 11.3 0.9 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mem_trans PF03547.18 ORY08093.1 - 2.6e-17 62.3 9.4 9.6e-11 40.7 1.8 2.1 2 0 0 2 2 2 2 Membrane transport protein HD PF01966.22 ORY08094.1 - 0.017 15.4 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 HD domain RBP_receptor PF14752.6 ORY08096.1 - 2.3e-25 89.2 15.1 3e-25 88.9 15.1 1.1 1 0 0 1 1 1 1 Retinol binding protein receptor adh_short PF00106.25 ORY08097.1 - 3.8e-15 55.9 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY08097.1 - 3.4e-07 30.4 0.0 4.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY08097.1 - 5.2e-07 29.5 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 ORY08097.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Y_phosphatase2 PF03162.13 ORY08099.1 - 4.2e-44 150.0 0.0 5.2e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY08099.1 - 0.003 17.2 0.0 0.0077 15.8 0.0 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase RRM_1 PF00076.22 ORY08100.1 - 1.2e-15 57.1 0.5 1.7e-15 56.6 0.5 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY08100.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RCC1 PF00415.18 ORY08101.1 - 1.1e-60 202.1 23.7 1.6e-11 44.6 0.5 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY08101.1 - 9.1e-49 162.4 39.4 1.4e-12 47.0 0.1 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 ORY08101.1 - 0.26 11.1 1.7 11 5.9 0.1 3.0 3 0 0 3 3 3 0 PapC C-terminal domain Kelch_4 PF13418.6 ORY08101.1 - 0.98 9.5 5.0 32 4.6 0.1 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Aminotran_5 PF00266.19 ORY08102.1 - 2.4e-30 105.7 0.0 3.4e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 ORY08102.1 - 2.9e-05 24.1 0.4 0.0027 17.7 0.1 2.8 2 1 1 3 3 3 1 B12 binding domain Cys_Met_Meta_PP PF01053.20 ORY08102.1 - 0.0001 21.0 0.0 0.00015 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme KR PF08659.10 ORY08102.1 - 0.043 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 KR domain WD40 PF00400.32 ORY08103.1 - 8.1e-31 105.6 16.6 0.0003 21.5 0.2 12.2 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY08103.1 - 2.3e-15 56.6 0.0 0.0019 18.5 0.0 7.6 7 1 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY08103.1 - 4.3e-07 29.6 2.8 0.08 12.3 0.1 4.5 4 1 1 5 5 5 2 WD40-like domain PD40 PF07676.12 ORY08103.1 - 0.00016 21.5 0.0 3.6 7.6 0.0 4.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 ORY08103.1 - 0.0058 16.0 0.7 17 4.6 0.0 4.6 4 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.9 ORY08103.1 - 0.0077 14.9 0.0 0.021 13.5 0.0 1.8 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 ORY08103.1 - 0.011 14.8 0.3 19 4.1 0.0 4.3 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 ORY08103.1 - 0.019 14.3 0.1 27 3.9 0.0 4.0 5 0 0 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-C3HC4_3 PF13920.6 ORY08104.1 - 1 9.3 9.0 3.5 7.6 9.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_46 PF01374.18 ORY08106.1 - 5.2e-36 124.3 0.0 6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 ORY08107.1 - 1.1e-40 139.5 0.0 1.4e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 DMRL_synthase PF00885.19 ORY08108.1 - 7.6e-57 191.1 0.0 8.8e-57 190.9 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SNF2_N PF00176.23 ORY08109.1 - 3.5e-72 243.0 1.2 9e-72 241.7 1.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY08109.1 - 1.2e-19 70.7 0.1 9.4e-18 64.6 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 ORY08109.1 - 1.8e-19 69.6 0.5 4.8e-19 68.2 0.5 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 ORY08109.1 - 1.1e-18 67.3 12.8 1.1e-18 67.3 12.8 3.5 3 0 0 3 3 3 1 HSA SnAC PF14619.6 ORY08109.1 - 1.5e-13 51.1 5.8 1.5e-13 51.1 5.8 4.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 ORY08109.1 - 3.8e-11 42.6 0.1 1e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 ORY08109.1 - 1e-10 41.9 3.1 7.2e-10 39.1 0.1 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Phage_AlpA PF05930.12 ORY08110.1 - 0.0013 18.6 0.3 68 3.4 0.0 6.7 8 1 1 9 9 9 2 Prophage CP4-57 regulatory protein (AlpA) Ribosomal_S19 PF00203.21 ORY08111.1 - 1e-36 124.6 1.1 1.5e-36 124.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 RCC1 PF00415.18 ORY08112.1 - 3e-75 248.7 1.0 3.2e-13 50.1 0.0 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY08112.1 - 8e-47 156.2 28.5 3.9e-09 36.1 1.6 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 ORY08112.1 - 0.0025 18.3 2.4 75 3.8 0.0 5.5 5 1 1 6 6 6 0 SUKH-3 immunity protein Hira PF07569.11 ORY08112.1 - 0.032 14.0 0.0 7.8 6.1 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split DUF4213 PF13938.6 ORY08112.1 - 0.043 14.0 3.0 13 6.1 0.0 3.4 2 2 1 3 3 3 0 Putative heavy-metal chelation Peptidase_C25_C PF03785.14 ORY08112.1 - 0.17 11.7 1.1 3.3 7.6 0.1 3.2 3 1 1 4 4 4 0 Peptidase family C25, C terminal ig-like domain Ribosomal_L26 PF16906.5 ORY08114.1 - 5.3e-37 126.1 3.8 7.1e-37 125.7 3.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY08114.1 - 6.8e-10 38.6 1.1 6.8e-10 38.6 1.1 2.0 3 0 0 3 3 3 1 KOW motif MBOAT PF03062.19 ORY08115.1 - 3.7e-51 174.5 12.2 3.7e-51 174.5 12.2 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Sulfotransfer_4 PF17784.1 ORY08116.1 - 5e-63 212.8 0.0 5.7e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY08116.1 - 0.0025 18.2 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY08116.1 - 0.1 12.1 0.0 0.34 10.4 0.0 1.8 2 1 0 2 2 2 0 Sulfotransferase domain RNase_T PF00929.24 ORY08118.1 - 1.8e-18 67.6 0.0 3.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 ORY08118.1 - 1.4e-10 40.9 0.0 9.8e-06 25.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY08118.1 - 0.13 12.4 0.2 34 4.6 0.0 3.6 3 2 1 4 4 4 0 RNA recognition motif dCMP_cyt_deam_1 PF00383.23 ORY08120.1 - 2.8e-18 65.7 0.1 4.4e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY08120.1 - 3.9e-13 49.3 0.1 5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 ORY08120.1 - 2.2e-05 24.6 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase FumaraseC_C PF10415.9 ORY08120.1 - 0.025 15.0 0.2 0.15 12.5 0.2 2.3 2 0 0 2 2 2 0 Fumarase C C-terminus Inv-AAD PF18785.1 ORY08120.1 - 0.25 11.2 3.0 0.39 10.6 0.2 2.6 3 1 0 3 3 3 0 Invertebrate-AID/APOBEC-deaminase Peptidase_S8 PF00082.22 ORY08121.1 - 4.5e-29 101.7 9.5 1.4e-28 100.0 9.5 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY08121.1 - 0.0036 17.9 0.0 0.1 13.3 0.0 2.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 SMC_N PF02463.19 ORY08121.1 - 0.0037 16.7 0.2 0.05 13.0 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Fungal_trans PF04082.18 ORY08122.1 - 4.6e-17 61.9 4.7 4.6e-17 61.9 4.7 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY08123.1 - 9.9e-12 44.8 11.4 1.5e-11 44.2 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain R3H PF01424.22 ORY08124.1 - 1.2e-12 47.6 0.0 3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 ORY08124.1 - 1e-10 41.3 3.1 2.4e-10 40.1 3.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY08124.1 - 4.7e-05 23.4 0.3 0.00019 21.4 0.3 2.1 1 0 0 1 1 1 1 G-patch domain Rcd1 PF04078.13 ORY08125.1 - 1.7e-115 384.8 2.3 1.9e-115 384.6 2.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SNF2_N PF00176.23 ORY08127.1 - 1.5e-65 221.2 0.1 3e-65 220.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 ORY08127.1 - 3.4e-25 88.3 2.3 3.4e-25 88.3 2.3 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.24 ORY08127.1 - 5.8e-24 83.7 2.4 6.5e-16 58.0 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ORY08127.1 - 7.3e-20 71.4 0.0 2e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY08127.1 - 4.4e-10 39.8 0.0 1.7e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 ORY08127.1 - 1.5e-07 31.8 0.1 1.5e-07 31.8 0.1 4.0 4 0 0 4 4 3 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 ORY08127.1 - 1.3e-06 29.0 3.2 2.1e-06 28.3 0.2 3.0 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 HDA2-3 PF11496.8 ORY08127.1 - 4.1e-05 22.9 0.1 0.00018 20.8 0.1 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 ORY08127.1 - 5e-05 22.6 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CHDCT2 PF08074.11 ORY08127.1 - 6.1e-05 23.3 0.4 0.00033 20.9 0.1 2.6 2 1 0 2 2 2 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 ORY08127.1 - 0.001 19.1 3.1 0.0019 18.2 0.0 3.0 3 0 0 3 3 3 1 SLIDE AdoHcyase PF05221.17 ORY08128.1 - 1.9e-135 450.8 0.0 2.4e-74 250.2 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ORY08128.1 - 3.4e-85 284.1 4.5 5.4e-85 283.4 4.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY08128.1 - 1.5e-07 30.9 0.4 2.9e-07 30.0 0.4 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORY08128.1 - 8.5e-05 22.2 0.3 0.00015 21.4 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ORY08128.1 - 0.0036 17.6 0.1 0.0085 16.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain TFIIA_gamma_N PF02268.16 ORY08129.1 - 2.1e-26 91.7 0.2 2.9e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 ORY08129.1 - 1.7e-24 85.7 1.4 2.6e-24 85.1 1.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DASH_Dad3 PF08656.10 ORY08130.1 - 9.2e-18 64.1 0.3 1.1e-17 63.8 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DHC_N1 PF08385.12 ORY08130.1 - 0.07 11.8 0.0 0.08 11.6 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 YojJ PF10372.9 ORY08130.1 - 0.09 12.9 0.0 14 5.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF543 PF04418.12 ORY08131.1 - 1.6e-25 88.9 0.0 1.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ndc1_Nup PF09531.10 ORY08131.1 - 0.063 12.0 0.0 0.063 12.0 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Synaptobrevin PF00957.21 ORY08132.1 - 3.5e-35 119.7 1.8 5.4e-35 119.1 1.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY08132.1 - 4.5e-29 100.3 0.1 7.5e-29 99.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RPN1_RPN2_N PF17781.1 ORY08133.1 - 3.6e-125 417.4 5.5 7e-125 416.5 5.5 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 ORY08133.1 - 5e-32 109.7 0.1 9.9e-32 108.8 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 ORY08133.1 - 1.1e-31 107.7 18.7 6e-07 29.6 0.2 8.9 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY08133.1 - 4e-05 23.9 0.6 0.41 11.1 0.0 4.8 5 1 1 6 6 6 2 HEAT repeats DUF2776 PF10951.8 ORY08133.1 - 0.028 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) Stn1_C PF12659.7 ORY08133.1 - 0.03 14.3 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH EspB_PE PF18625.1 ORY08133.1 - 0.3 11.6 2.3 11 6.6 0.1 3.1 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain MRP-L20 PF12824.7 ORY08134.1 - 5e-25 88.6 2.0 5.5e-25 88.4 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 ORY08134.1 - 0.0037 17.8 0.1 0.0037 17.8 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain Neugrin PF06413.11 ORY08134.1 - 0.0039 17.2 0.1 0.0048 16.9 0.1 1.2 1 0 0 1 1 1 1 Neugrin HTH_11 PF08279.12 ORY08134.1 - 0.043 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain DNA_meth_N PF18284.1 ORY08134.1 - 0.1 12.5 2.4 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 DNA methylase N-terminal domain Arm PF00514.23 ORY08135.1 - 2.4e-12 46.4 14.0 0.0021 18.0 0.2 7.8 8 1 1 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY08135.1 - 4.5e-06 26.5 7.1 0.45 10.9 0.0 7.2 6 1 1 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 ORY08135.1 - 1.9e-05 25.0 2.8 6.9 7.1 0.0 6.1 3 2 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 ORY08135.1 - 0.00011 22.7 8.9 4.4 7.9 0.0 6.2 6 1 1 7 7 7 1 HEAT-like repeat Atx10homo_assoc PF09759.9 ORY08135.1 - 0.5 10.4 2.5 5 7.2 0.0 3.6 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain SAP18 PF06487.12 ORY08136.1 - 8.5e-38 129.7 0.1 1.2e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) ATP-synt_F PF01990.17 ORY08137.1 - 2.1e-28 98.4 0.4 1.1e-27 96.2 0.1 1.9 2 0 0 2 2 2 1 ATP synthase (F/14-kDa) subunit Rad21_Rec8_N PF04825.13 ORY08137.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.3 1 1 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Pribosyl_synth PF14572.6 ORY08138.1 - 2.5e-46 158.0 0.8 1.6e-38 132.6 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY08138.1 - 1.7e-35 121.4 0.0 1.3e-33 115.3 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY08138.1 - 1.7e-13 50.4 0.2 3.5e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_17 PF00332.18 ORY08139.1 - 3.6e-12 46.5 1.2 3.1e-08 33.6 1.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 CwsA PF10814.8 ORY08139.1 - 0.23 11.6 0.3 0.4 10.9 0.3 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Dicty_CAR PF05462.11 ORY08140.1 - 0.0017 17.6 9.6 0.0026 17.0 9.4 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor RXT2_N PF08595.11 ORY08142.1 - 3.7e-06 27.1 5.8 4.5e-05 23.5 0.2 2.8 1 1 2 3 3 3 2 RXT2-like, N-terminal GCV_H PF01597.19 ORY08143.1 - 0.00058 19.7 0.2 0.0056 16.6 0.1 2.1 2 0 0 2 2 2 1 Glycine cleavage H-protein AhpC-TSA PF00578.21 ORY08144.1 - 1.6e-34 118.5 0.0 2.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY08144.1 - 7.7e-12 45.2 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY08144.1 - 3.3e-09 36.4 0.0 5.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box-like PF12937.7 ORY08145.1 - 4.6e-11 42.4 1.8 7.3e-11 41.8 0.1 2.3 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.6 ORY08145.1 - 1.3e-07 31.0 9.7 0.099 12.7 0.3 5.3 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.33 ORY08145.1 - 1.6e-07 31.0 1.1 4.4e-07 29.6 1.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORY08145.1 - 0.00025 21.3 0.0 1.6 9.3 0.0 4.3 2 2 2 4 4 4 1 Leucine Rich repeats (2 copies) PRANC PF09372.10 ORY08145.1 - 0.07 13.5 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 PRANC domain F-box_4 PF15966.5 ORY08145.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box Utp21 PF04192.12 ORY08146.1 - 1.2e-74 250.8 0.0 2.1e-74 250.0 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 ORY08146.1 - 1.8e-25 88.7 17.8 1.1e-08 35.6 0.4 8.9 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY08146.1 - 8.1e-20 70.9 0.2 1.5e-05 25.2 0.0 5.8 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY08146.1 - 3e-05 24.0 0.1 0.25 11.2 0.0 3.7 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY08146.1 - 0.00024 20.2 0.3 0.096 11.6 0.0 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY08146.1 - 0.00035 19.4 1.0 1.2 7.7 0.1 4.0 2 1 2 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY08146.1 - 0.00078 18.9 3.9 0.18 11.1 0.1 3.5 3 0 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 ORY08146.1 - 0.0015 17.1 0.8 0.012 14.2 0.1 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain Utp12 PF04003.12 ORY08146.1 - 0.0031 17.8 0.0 0.0065 16.8 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.11 ORY08146.1 - 0.012 14.4 0.0 2.4 6.8 0.0 2.5 1 1 0 2 2 2 0 Nup133 N terminal like Imm64 PF15600.6 ORY08146.1 - 0.019 14.6 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 64 PD40 PF07676.12 ORY08146.1 - 0.026 14.5 0.4 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ndc1_Nup PF09531.10 ORY08148.1 - 0.023 13.4 2.2 0.03 13.1 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3784 PF12650.7 ORY08153.1 - 0.56 10.4 7.1 2.5 8.4 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3784 PF12650.7 ORY08155.1 - 0.22 11.8 8.1 0.59 10.4 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3810 PF12725.7 ORY08155.1 - 6.1 6.1 5.6 25 4.1 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3784 PF12650.7 ORY08157.1 - 0.57 10.4 6.9 2.5 8.4 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF2615 PF11027.8 ORY08159.1 - 0.44 10.7 1.1 5.2 7.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF3784 PF12650.7 ORY08159.1 - 0.57 10.4 6.9 2.5 8.4 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3784 PF12650.7 ORY08161.1 - 0.14 12.4 7.3 0.59 10.4 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3810 PF12725.7 ORY08161.1 - 6.1 6.1 5.6 25 4.1 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Prefoldin PF02996.17 ORY08166.1 - 2.1e-20 72.8 0.1 4.4e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 ORY08166.1 - 3.5e-17 63.0 7.1 4.2e-15 56.4 0.7 4.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 ORY08166.1 - 1.4e-12 47.5 0.2 1.2e-11 44.6 0.1 2.6 2 1 0 2 2 2 1 Prefoldin subunit XhlA PF10779.9 ORY08166.1 - 0.018 15.3 3.0 3 8.1 0.3 2.9 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_VP1054 PF05789.11 ORY08166.1 - 0.098 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus VP1054 protein TFIIF_alpha PF05793.12 ORY08166.1 - 0.13 10.8 28.8 0.22 10.1 28.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 ORY08166.1 - 2.5 7.3 13.3 4.2 6.6 13.3 1.3 1 0 0 1 1 1 0 NOA36 protein Rad1 PF02144.16 ORY08167.1 - 3.8e-81 272.2 5.6 4.4e-81 272.0 5.6 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 ORY08167.1 - 4.2e-05 23.1 0.0 8.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Rad9 zf-C3HC4_2 PF13923.6 ORY08168.1 - 5.1e-09 35.8 16.9 5.1e-09 35.8 16.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY08168.1 - 1.9e-07 30.9 14.1 1.9e-07 30.9 14.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY08168.1 - 4.3e-07 30.2 17.1 4.3e-07 30.2 17.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY08168.1 - 8.6e-07 28.7 17.3 8.6e-07 28.7 17.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY08168.1 - 8.2e-06 25.9 17.0 8.2e-06 25.9 17.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY08168.1 - 0.00012 22.0 13.4 0.00032 20.7 13.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TFIIA PF03153.13 ORY08168.1 - 0.003 17.6 16.1 0.003 17.6 16.1 2.7 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-rbx1 PF12678.7 ORY08168.1 - 0.0086 16.3 16.3 0.0086 16.3 16.3 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY08168.1 - 0.016 15.0 13.0 0.016 15.0 13.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF745 PF05335.13 ORY08168.1 - 0.21 11.3 0.3 0.38 10.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Ndc1_Nup PF09531.10 ORY08168.1 - 1.5 7.4 12.0 2.3 6.8 12.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_10 PF16685.5 ORY08168.1 - 2.5 8.3 16.1 0.11 12.6 10.3 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 TMEM247 PF15444.6 ORY08168.1 - 5.9 6.9 11.5 0.075 13.1 3.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 247 DUF1272 PF06906.11 ORY08168.1 - 9.8 6.4 18.6 7.1 6.8 10.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) CBS PF00571.28 ORY08169.1 - 1.4e-34 118.3 9.8 1.5e-07 31.7 0.0 5.5 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 ORY08169.1 - 2.5e-10 40.1 0.1 6.6e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 PB1 domain Glyco_hydro_15 PF00723.21 ORY08170.1 - 4.4e-68 230.1 0.0 2.8e-66 224.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 LisH PF08513.11 ORY08171.1 - 7.4e-05 22.6 0.3 0.00014 21.7 0.3 1.4 1 0 0 1 1 1 1 LisH DUF2242 PF10001.9 ORY08171.1 - 0.56 10.4 4.8 1.5 9.0 4.8 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) Sec16_C PF12931.7 ORY08172.1 - 1.8e-59 201.9 0.0 2.6e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 ORY08172.1 - 1.6e-24 86.7 0.0 4e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region GTP1_OBG PF01018.22 ORY08173.1 - 4e-40 136.9 2.4 1.5e-28 99.4 1.5 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 ORY08173.1 - 7.3e-20 71.2 0.0 2.2e-19 69.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY08173.1 - 6.8e-07 28.9 0.0 1.6e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 ORY08173.1 - 0.00012 21.6 0.0 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY08173.1 - 0.0026 17.4 0.0 0.0061 16.2 0.0 1.7 1 0 0 1 1 1 1 Ras family APG12 PF04110.13 ORY08174.1 - 1.6e-32 111.8 0.0 1.7e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 ORY08174.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like P3A PF08727.11 ORY08174.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Poliovirus 3A protein like Defensin_beta PF00711.19 ORY08175.1 - 0.041 13.9 0.4 0.074 13.1 0.4 1.4 1 0 0 1 1 1 0 Beta defensin Hrs_helical PF12210.8 ORY08175.1 - 0.049 14.2 0.1 0.17 12.4 0.1 2.0 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate YtzH PF14165.6 ORY08175.1 - 8.9 6.8 6.7 46 4.5 0.2 4.0 4 0 0 4 4 4 0 YtzH-like protein CSD PF00313.22 ORY08176.1 - 7.5e-23 80.2 0.1 1.1e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ORY08176.1 - 0.003 17.2 0.1 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain ARS2 PF04959.13 ORY08176.1 - 0.13 12.6 1.5 0.12 12.7 1.5 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 GDA1_CD39 PF01150.17 ORY08177.1 - 1.5e-98 330.2 0.0 1.8e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 ORY08177.1 - 0.0039 16.7 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Peptidase_S8 PF00082.22 ORY08178.1 - 3.5e-31 108.6 0.1 4.2e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY08179.1 - 3e-18 66.6 0.1 5.6e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain Peptidase_S8 PF00082.22 ORY08179.1 - 7.6e-15 54.9 0.1 1.2e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Subtilase family DUF4232 PF14016.6 ORY08179.1 - 2.4e-05 24.5 0.1 5.9e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) fn3_6 PF17766.1 ORY08179.1 - 0.036 14.3 0.9 0.41 10.8 0.2 2.6 2 1 0 2 2 2 0 Fibronectin type-III domain NPCBM_assoc PF10633.9 ORY08179.1 - 0.1 12.9 1.0 2.1 8.6 0.3 3.0 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Motile_Sperm PF00635.26 ORY08179.1 - 0.16 11.8 0.6 12 5.8 0.0 2.7 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Methyltr_RsmB-F PF01189.17 ORY08239.1 - 2.6e-29 102.3 0.0 4.4e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 ORY08239.1 - 2.4e-07 31.4 0.1 4.1e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY08239.1 - 1e-05 25.4 0.1 0.001 18.9 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.19 ORY08239.1 - 0.003 17.7 0.0 0.012 15.7 0.0 1.9 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ORY08239.1 - 0.0058 16.5 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08239.1 - 0.0084 16.7 0.1 0.095 13.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 ORY08239.1 - 0.072 12.6 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 ORY08239.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_L35Ae PF01247.18 ORY08240.1 - 1.3e-45 153.5 0.8 1.5e-45 153.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY08240.1 - 0.0021 18.2 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Requiem_N PF14051.6 ORY08241.1 - 0.12 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. YchF-GTPase_C PF06071.13 ORY08243.1 - 5.9e-41 138.5 0.1 1.3e-40 137.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY08243.1 - 1.1e-22 80.3 0.0 2.4e-22 79.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY08243.1 - 8.7e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY08243.1 - 0.0049 16.9 0.0 0.69 9.9 0.1 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 ORY08243.1 - 0.015 14.3 0.1 0.045 12.7 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 ORY08243.1 - 0.037 13.8 0.0 0.35 10.6 0.0 2.2 1 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AsmA_2 PF13502.6 ORY08244.1 - 0.0033 17.0 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 AsmA-like C-terminal region FA_desaturase PF00487.24 ORY08245.1 - 8.3e-28 97.9 22.4 1.3e-27 97.3 22.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY08245.1 - 2.5e-07 30.9 0.0 6.6e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) DUF2157 PF09925.9 ORY08245.1 - 0.041 13.7 3.1 0.45 10.3 3.1 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Fasciclin PF02469.22 ORY08246.1 - 8e-46 155.4 0.0 2.1e-21 76.5 0.0 3.2 2 1 0 2 2 2 2 Fasciclin domain DEAD PF00270.29 ORY08247.1 - 9e-29 100.5 0.0 2.2e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY08247.1 - 9.2e-23 80.7 0.2 2e-22 79.6 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY08247.1 - 1.1e-08 35.2 0.0 3.7e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY08247.1 - 0.025 14.9 0.3 25 5.1 0.0 3.5 2 1 1 3 3 3 0 AAA domain CODH_A_N PF18537.1 ORY08247.1 - 0.085 12.9 0.0 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain PhoH PF02562.16 ORY08247.1 - 0.099 12.1 0.2 9 5.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF5616 PF18481.1 ORY08247.1 - 0.11 12.8 0.1 0.48 10.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Sensor PF13796.6 ORY08248.1 - 0.0001 22.4 16.1 0.00021 21.4 15.2 1.7 1 1 1 2 2 2 2 Putative sensor MPS-4 PF17523.2 ORY08248.1 - 6.6 6.9 10.2 0.9 9.7 1.5 2.6 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 MFS_1 PF07690.16 ORY08249.1 - 1.5e-40 139.2 43.6 7.1e-34 117.3 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08249.1 - 6.2e-12 45.1 9.3 3.4e-11 42.7 10.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY08249.1 - 0.00019 20.0 1.4 0.27 9.6 0.3 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector ECF-ribofla_trS PF07155.12 ORY08249.1 - 0.27 11.2 6.9 0.093 12.7 2.7 2.5 2 1 0 2 2 2 0 ECF-type riboflavin transporter, S component RhoGEF PF00621.20 ORY08250.1 - 3.7e-49 167.4 3.6 7.5e-49 166.4 3.6 1.6 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 ORY08250.1 - 3.5e-16 58.7 7.7 3e-10 39.7 2.6 3.4 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY08250.1 - 1.3e-14 54.1 14.9 8.4e-07 29.2 1.5 4.7 1 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY08250.1 - 0.0089 15.5 3.2 0.13 11.8 1.5 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 ORY08250.1 - 0.049 14.2 19.8 2.5 9.0 0.2 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY08250.1 - 1.9 8.8 21.5 7.4 6.9 0.5 6.0 6 0 0 6 6 6 0 Leucine Rich repeat RasGEF PF00617.19 ORY08252.1 - 1.1e-45 156.0 1.2 1.6e-45 155.4 1.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY08252.1 - 4.8e-15 55.7 6.2 5.4e-15 55.5 0.1 3.3 1 1 2 3 3 3 1 RasGEF N-terminal motif Endonuc_Holl PF10107.9 ORY08252.1 - 0.046 13.6 1.3 0.17 11.7 0.0 2.3 3 0 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase ERO1 PF04137.15 ORY08253.1 - 3.5e-134 447.5 1.1 4e-134 447.3 1.1 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) SYCP2_ARLD PF18581.1 ORY08253.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain AgrD PF05931.11 ORY08253.1 - 0.71 9.9 4.0 0.48 10.5 0.4 2.5 3 0 0 3 3 3 0 Staphylococcal AgrD protein Aa_trans PF01490.18 ORY08254.1 - 1.5e-59 201.7 28.8 1.8e-59 201.5 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORY08254.1 - 2 7.2 36.0 0.061 12.1 19.4 3.8 2 2 0 2 2 2 0 Spore germination protein SSF PF00474.17 ORY08255.1 - 1.1e-12 47.5 14.0 1.1e-12 47.5 14.0 2.7 2 1 0 2 2 2 1 Sodium:solute symporter family DUF4405 PF14358.6 ORY08255.1 - 0.091 13.3 0.0 0.091 13.3 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) DUF4396 PF14342.6 ORY08255.1 - 0.84 10.0 0.0 0.84 10.0 0.0 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4396) FMO-like PF00743.19 ORY08256.1 - 5.7e-19 67.9 0.0 1.5e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORY08256.1 - 8.6e-15 54.7 0.1 1.4e-12 47.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY08256.1 - 1.4e-10 41.3 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY08256.1 - 7e-10 38.6 0.2 1.6e-08 34.2 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY08256.1 - 5e-07 29.2 0.0 0.00032 20.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY08256.1 - 3.2e-06 27.0 0.8 0.00025 20.8 0.1 2.8 2 2 1 3 3 3 1 FAD dependent oxidoreductase APP_N PF02177.16 ORY08256.1 - 0.035 14.5 0.3 0.097 13.1 0.3 1.7 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Sacchrp_dh_NADP PF03435.18 ORY08257.1 - 4.8e-20 72.1 0.0 8.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 ORY08257.1 - 0.042 13.0 0.1 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY08257.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Mito_fiss_Elm1 PF06258.11 ORY08258.1 - 1.2e-53 182.2 0.0 1.5e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 fragilysinNterm PF16376.5 ORY08258.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of fragilysin C6 PF01681.17 ORY08258.1 - 0.084 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 C6 domain MFS_1 PF07690.16 ORY08259.1 - 1.1e-28 100.2 36.4 2.3e-18 66.3 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY08259.1 - 6.3e-12 45.1 14.0 2.4e-06 26.7 0.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1129 PF06570.11 ORY08259.1 - 0.47 9.9 4.9 0.19 11.2 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) p450 PF00067.22 ORY08260.1 - 4.8e-45 154.2 0.0 6.2e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPK_catalytic PF04263.16 ORY08261.1 - 9.2e-40 135.4 0.0 2.4e-39 134.1 0.0 1.6 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 ORY08261.1 - 5e-20 71.0 0.4 8.6e-20 70.2 0.4 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF846 PF05832.12 ORY08262.1 - 2.8e-57 192.6 12.0 3.3e-57 192.4 12.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 ORY08262.1 - 0.011 16.0 7.1 0.58 10.5 1.1 2.1 2 0 0 2 2 2 0 YwiC-like protein Spore_YhaL PF14147.6 ORY08262.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 Sporulation protein YhaL DUF1430 PF07242.11 ORY08262.1 - 0.92 9.8 7.6 0.65 10.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Halogen_Hydrol PF10112.9 ORY08262.1 - 2.2 8.3 7.5 9.8 6.2 0.6 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HMG_box PF00505.19 ORY08263.1 - 7e-21 74.4 1.8 8.5e-21 74.1 1.8 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY08263.1 - 2.7e-07 31.1 0.6 3.5e-07 30.7 0.6 1.1 1 0 0 1 1 1 1 HMG-box domain EXS PF03124.14 ORY08264.1 - 5e-79 266.0 25.5 1.9e-68 231.2 20.5 2.0 1 1 1 2 2 2 2 EXS family SPX PF03105.19 ORY08265.1 - 1.5e-40 140.3 27.4 7.5e-17 62.3 8.2 3.0 1 1 2 3 3 3 3 SPX domain Cas_DxTHG PF09455.10 ORY08265.1 - 0.0054 16.4 3.1 0.0071 16.0 3.1 1.3 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family ER PF01133.17 ORY08265.1 - 0.058 13.4 0.8 0.94 9.5 0.7 2.6 2 1 0 2 2 2 0 Enhancer of rudimentary CorA PF01544.18 ORY08265.1 - 1.2 8.4 5.1 0.73 9.1 2.9 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Chitin_bind_1 PF00187.19 ORY08266.1 - 1.5e-09 38.1 21.0 2.7e-09 37.4 21.0 1.4 1 0 0 1 1 1 1 Chitin recognition protein Plasmodium_Vir PF05795.11 ORY08266.1 - 0.62 9.4 4.0 1.6 8.0 4.0 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein AAA_25 PF13481.6 ORY08267.1 - 8.6e-26 90.7 0.0 1.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 ORY08267.1 - 8.4e-16 58.1 0.0 1.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 ORY08267.1 - 2.4e-09 37.6 0.0 6.3e-09 36.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 ORY08267.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 ORY08267.1 - 7.5e-06 26.4 0.0 1.9e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Toprim_2 PF13155.6 ORY08267.1 - 0.00033 21.0 0.0 0.00094 19.6 0.0 1.7 1 0 0 1 1 1 1 Toprim-like AAA_23 PF13476.6 ORY08267.1 - 0.00072 20.1 0.1 0.004 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Toprim_4 PF13662.6 ORY08267.1 - 0.0036 17.7 0.0 0.052 14.0 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ABC_tran PF00005.27 ORY08267.1 - 0.0098 16.4 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 ORY08267.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORY08267.1 - 0.014 15.3 0.1 0.077 12.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase HTH_CodY PF08222.11 ORY08267.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain AAA_24 PF13479.6 ORY08267.1 - 0.017 14.9 0.3 0.052 13.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY08267.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 ORY08267.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Glyco_hydro_31 PF01055.26 ORY08267.1 - 0.042 13.0 0.3 0.057 12.6 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 NACHT PF05729.12 ORY08267.1 - 0.045 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 ORY08267.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TF_Zn_Ribbon PF08271.12 ORY08267.1 - 0.093 12.3 2.6 0.24 10.9 2.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_29 PF13555.6 ORY08267.1 - 0.1 12.4 0.2 0.3 10.9 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 ORY08267.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Toprim PF01751.22 ORY08267.1 - 0.13 12.5 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 Toprim domain zinc_ribbon_4 PF13717.6 ORY08267.1 - 1.5 8.8 3.5 16 5.5 0.9 2.4 1 1 1 2 2 2 0 zinc-ribbon domain DUF727 PF05303.12 ORY08269.1 - 0.0039 17.2 0.0 0.005 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Aminotran_3 PF00202.21 ORY08270.1 - 1.3e-124 416.0 0.0 1.5e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III OAM_dimer PF16554.5 ORY08270.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase DUF676 PF05057.14 ORY08271.1 - 2.3e-06 27.3 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY08271.1 - 4.4e-05 24.2 0.0 6.9e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY08271.1 - 0.0004 19.8 0.0 0.87 8.9 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 ORY08271.1 - 0.00049 19.9 0.7 0.0033 17.2 0.1 2.5 2 2 0 2 2 2 1 PGAP1-like protein DUF2974 PF11187.8 ORY08271.1 - 0.0026 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 ORY08271.1 - 0.0056 16.8 0.0 0.017 15.2 0.0 1.8 2 1 0 2 2 2 1 Thioesterase domain LCAT PF02450.15 ORY08271.1 - 0.021 14.0 0.2 0.33 10.1 0.2 2.1 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF4918 PF16265.5 ORY08271.1 - 0.069 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) Hydrolase_4 PF12146.8 ORY08271.1 - 0.076 12.3 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LRR_6 PF13516.6 ORY08272.1 - 1.6e-12 46.4 5.7 0.0047 16.9 0.5 5.1 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 ORY08272.1 - 3.1e-06 27.4 5.9 0.11 12.9 0.0 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY08272.1 - 5.4e-06 26.2 1.6 1.2e-05 25.0 0.1 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 ORY08272.1 - 0.0008 19.2 0.1 0.0035 17.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY08272.1 - 0.0017 18.6 7.1 24 6.0 0.2 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat DUF1754 PF08555.10 ORY08273.1 - 4.2e-05 24.3 7.5 0.0092 16.8 0.6 2.5 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) DUF4897 PF16238.5 ORY08273.1 - 0.071 12.9 0.5 0.091 12.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) DUF4630 PF15443.6 ORY08273.1 - 0.099 12.8 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) MFS_1 PF07690.16 ORY08274.1 - 1.8e-30 106.1 39.0 2e-30 105.9 35.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 ORY08274.1 - 0.12 12.6 0.3 0.12 12.6 0.3 4.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2304) Vma12 PF11712.8 ORY08274.1 - 0.17 11.9 3.5 0.63 10.1 1.5 2.8 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DHHC PF01529.20 ORY08275.1 - 7.7e-26 90.8 11.5 1.1e-25 90.3 11.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase ADH_N PF08240.12 ORY08275.1 - 0.15 11.9 3.2 0.25 11.3 3.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain IGFBP PF00219.18 ORY08275.1 - 0.4 11.4 7.3 0.87 10.3 7.3 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein DUF1394 PF07159.12 ORY08276.1 - 4.2e-110 367.7 2.6 4.8e-110 367.6 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) CARD PF00619.21 ORY08276.1 - 0.0072 16.3 0.1 0.058 13.4 0.0 2.4 2 1 0 2 2 2 1 Caspase recruitment domain SET PF00856.28 ORY08277.1 - 1.7e-22 80.6 0.3 4.6e-22 79.2 0.3 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 ORY08277.1 - 1.9e-20 73.5 4.3 1.9e-20 73.5 4.3 2.7 3 0 0 3 3 3 1 Pre-SET motif AWS PF17907.1 ORY08277.1 - 0.0023 17.9 2.1 0.0023 17.9 2.1 2.8 4 0 0 4 4 4 1 AWS domain Phosducin PF02114.16 ORY08278.1 - 6.7e-33 113.8 1.4 1.2e-25 89.9 0.1 2.0 1 1 1 2 2 2 2 Phosducin Thioredoxin PF00085.20 ORY08278.1 - 0.14 12.1 0.0 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin CAP_GLY PF01302.25 ORY08279.1 - 2.1e-26 91.7 0.3 2.6e-26 91.4 0.3 1.1 1 0 0 1 1 1 1 CAP-Gly domain zf-C2H2_aberr PF17017.5 ORY08280.1 - 4.8e-06 26.8 9.5 0.04 14.1 0.5 3.2 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY08280.1 - 2.3e-05 24.6 14.1 0.0036 17.7 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY08280.1 - 0.0016 19.1 16.5 0.05 14.4 1.0 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY08280.1 - 0.002 18.7 9.9 0.28 11.8 0.0 4.2 3 1 1 4 4 4 2 FOXP coiled-coil domain OrsD PF12013.8 ORY08280.1 - 0.39 11.2 5.7 14 6.2 0.2 3.3 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Pro_isomerase PF00160.21 ORY08281.1 - 6.9e-47 159.7 0.2 7.8e-47 159.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GHMP_kinases_C PF08544.13 ORY08282.1 - 3.1e-08 33.9 0.0 7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ORY08282.1 - 2e-06 27.9 0.0 4.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 ORY08282.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature RRM_1 PF00076.22 ORY08283.1 - 3.5e-08 33.2 0.1 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.7 ORY08284.1 - 3.1e-34 117.6 10.9 1.3e-33 115.6 10.9 2.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 ORY08284.1 - 4.4e-19 68.8 0.2 2.8e-18 66.2 0.3 2.4 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain AAA PF00004.29 ORY08284.1 - 1.4e-18 67.6 0.0 3.6e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY08284.1 - 1.9e-11 44.7 0.0 8.6e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY08284.1 - 1.3e-10 41.7 0.0 7.6e-10 39.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain Cdc6_C PF09079.11 ORY08284.1 - 3.5e-10 39.7 0.1 1.5e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 ORY08284.1 - 3.5e-09 36.7 0.1 1.4e-08 34.8 0.1 2.1 1 0 0 1 1 1 1 AAA lid domain RRM_1 PF00076.22 ORY08284.1 - 0.0009 19.0 0.0 0.003 17.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 ORY08284.1 - 0.0037 17.2 0.2 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORY08284.1 - 0.0071 16.7 0.0 0.022 15.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 ORY08284.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 ORY08284.1 - 0.04 13.1 0.0 0.11 11.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORY08284.1 - 0.068 12.9 0.0 0.068 12.9 0.0 3.8 3 2 0 3 3 1 0 AAA domain AAA_14 PF13173.6 ORY08284.1 - 0.075 13.1 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 ORY08284.1 - 0.11 12.3 0.5 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 NTPase AT_hook PF02178.19 ORY08284.1 - 9.3 6.5 28.7 1.1 9.4 3.2 4.6 4 0 0 4 4 4 0 AT hook motif Mito_carr PF00153.27 ORY08285.1 - 8.2e-52 173.1 6.5 2.9e-20 72.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY08285.1 - 0.0095 15.1 1.0 0.66 9.1 0.0 3.0 2 1 2 4 4 4 1 Gammaproteobacterial serine protease PetG PF02529.15 ORY08285.1 - 0.029 14.2 0.3 0.1 12.4 0.2 2.1 1 1 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Calsarcin PF05556.11 ORY08285.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Syja_N PF02383.18 ORY08286.1 - 4.4e-82 275.9 0.3 4.4e-82 275.9 0.3 1.7 2 0 0 2 2 2 1 SacI homology domain CBF PF03914.17 ORY08287.1 - 6.6e-57 192.2 0.1 4.3e-56 189.6 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 ORY08287.1 - 0.085 12.9 4.4 0.11 12.5 0.2 3.0 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 OAD_gamma PF04277.13 ORY08287.1 - 9.1 7.0 9.9 0.24 12.0 0.9 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain zf-RING_4 PF14570.6 ORY08288.1 - 8.8e-23 79.9 12.2 1.7e-22 78.9 12.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 ORY08288.1 - 2.8e-08 33.4 0.0 3e-07 30.2 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 ORY08288.1 - 8.1e-08 32.0 8.5 8.1e-08 32.0 8.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 ORY08288.1 - 9e-06 25.2 2.3 1.2e-05 24.9 2.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 ORY08288.1 - 0.00011 22.0 9.6 0.0086 15.9 10.0 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY08288.1 - 0.0017 18.7 12.8 0.0046 17.3 12.8 1.7 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 ORY08288.1 - 0.0038 17.2 5.2 0.0038 17.2 5.2 1.7 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 ORY08288.1 - 0.0043 17.2 3.9 0.008 16.3 3.9 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Nup35_RRM_2 PF14605.6 ORY08288.1 - 0.0064 16.5 0.1 0.019 14.9 0.1 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 ORY08288.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 ORY08288.1 - 0.012 15.4 12.3 0.026 14.4 12.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ORY08288.1 - 0.015 15.1 0.4 5 7.1 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1154 PF06631.11 ORY08288.1 - 0.032 14.3 0.3 0.085 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) zf-C3HC4 PF00097.25 ORY08288.1 - 0.037 13.9 12.9 0.082 12.8 12.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_occluded PF16842.5 ORY08288.1 - 0.041 13.7 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-RING_UBOX PF13445.6 ORY08288.1 - 0.2 11.7 9.4 0.28 11.2 7.6 2.1 1 1 1 2 2 2 0 RING-type zinc-finger CH PF00307.31 ORY08289.1 - 2.1e-22 79.3 0.0 3.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 ORY08289.1 - 8.1e-06 25.4 0.4 1.4e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 Calponin family repeat Galactosyl_T PF01762.21 ORY08291.1 - 1.5e-28 100.0 0.0 2.6e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Gly_transf_sug PF04488.15 ORY08291.1 - 3e-11 43.8 0.0 1.1e-10 42.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif EOS1 PF12326.8 ORY08291.1 - 2e-10 40.9 10.2 8.4e-10 38.9 10.0 2.1 1 1 0 1 1 1 1 N-glycosylation protein Gb3_synth PF04572.12 ORY08291.1 - 1.8e-06 28.1 0.0 5.2e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Wzy_C_2 PF11846.8 ORY08291.1 - 0.029 14.3 0.2 0.064 13.2 0.2 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TcdA_TcdB PF12919.7 ORY08291.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF5410 PF17422.2 ORY08291.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5410) UQ_con PF00179.26 ORY08292.1 - 1.6e-53 180.2 0.0 1.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY08292.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY08292.1 - 0.088 13.1 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ORY08292.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain MKT1_C PF12246.8 ORY08293.1 - 1.1e-54 185.2 0.5 1.8e-54 184.5 0.5 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 ORY08293.1 - 1.3e-30 105.6 0.2 3.4e-30 104.2 0.2 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 ORY08293.1 - 1.1e-06 29.1 0.0 5.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 ORY08293.1 - 0.0016 18.8 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region Methyltr_RsmB-F PF01189.17 ORY08294.1 - 2.6e-27 95.8 0.0 3.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY08294.1 - 1.3e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase XPG_I PF00867.18 ORY08295.1 - 1.9e-24 85.8 0.2 5.9e-24 84.2 0.1 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 ORY08295.1 - 9.1e-24 83.9 0.0 2e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ORY08295.1 - 2.1e-06 27.4 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 ORY08295.1 - 0.0058 17.2 0.0 0.018 15.6 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 ORY08295.1 - 0.0067 16.5 0.3 0.04 14.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY08295.1 - 0.035 13.9 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY08295.1 - 0.036 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY08295.1 - 0.038 14.2 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_pol_lambd_f PF10391.9 ORY08295.1 - 0.069 13.0 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH PF00633.23 ORY08295.1 - 0.17 11.8 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PRCC PF10253.9 ORY08296.1 - 0.54 11.0 4.8 2.1 9.1 4.8 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting RasGEF PF00617.19 ORY08297.1 - 1.3e-21 77.6 7.7 1.8e-21 77.1 7.7 1.3 1 1 0 1 1 1 1 RasGEF domain Fe_dep_repr_C PF02742.15 ORY08297.1 - 0.31 11.1 4.0 11 6.2 0.8 2.5 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Zn_clus PF00172.18 ORY08298.1 - 6.3e-05 23.0 11.9 6.3e-05 23.0 11.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RFX5_DNA_bdg PF14621.6 ORY08298.1 - 0.11 12.2 0.4 0.16 11.7 0.4 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain zf-C2H2 PF00096.26 ORY08299.1 - 7.6e-13 48.1 10.5 1.3e-06 28.5 4.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY08299.1 - 6e-12 45.4 16.7 2.1e-09 37.4 0.8 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY08299.1 - 1.3e-07 31.9 9.0 0.0018 19.0 2.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY08299.1 - 0.0053 17.0 4.9 0.076 13.3 4.9 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY08299.1 - 0.015 15.3 5.1 0.072 13.1 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf_ZIC PF18366.1 ORY08299.1 - 0.13 12.4 1.1 6.3 7.0 0.2 2.1 2 0 0 2 2 2 0 Zic proteins zinc finger domain DcpS_C PF11969.8 ORY08300.1 - 4.3e-24 85.2 0.7 4.3e-24 85.2 0.7 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 ORY08300.1 - 1.1e-13 51.4 1.1 2.4e-13 50.3 1.1 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 ORY08300.1 - 6.1e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 HIT domain NAD_binding_10 PF13460.6 ORY08301.1 - 2.9e-05 24.1 0.0 3.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY08301.1 - 0.0039 16.2 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY08301.1 - 0.033 13.6 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY08301.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family CBFD_NFYB_HMF PF00808.23 ORY08302.1 - 2.7e-18 66.0 1.4 4.2e-18 65.4 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 ORY08302.1 - 0.05 13.6 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-W PF15510.6 ORY08302.1 - 0.096 12.9 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 CENP-W protein Maf1 PF09174.10 ORY08303.1 - 1.9e-61 207.3 0.8 2.2e-61 207.1 0.8 1.0 1 0 0 1 1 1 1 Maf1 regulator APC1_C PF18122.1 ORY08304.1 - 1.7e-30 106.2 0.1 3e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 ORY08304.1 - 5.5e-06 26.6 23.2 0.014 15.8 0.1 7.5 8 0 0 8 8 8 3 Proteasome/cyclosome repeat Securin PF04856.13 ORY08307.1 - 4.3e-08 33.4 4.8 5.5e-08 33.1 4.8 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor PAP2_C PF14360.6 ORY08308.1 - 2.1e-15 57.0 12.2 2.1e-15 57.0 12.2 2.5 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORY08308.1 - 2.4e-05 24.1 12.2 0.00012 21.8 12.2 2.1 1 1 0 1 1 1 1 PAP2 superfamily BRI3BP PF14965.6 ORY08308.1 - 0.032 13.8 0.3 0.032 13.8 0.3 2.7 3 0 0 3 3 3 0 Negative regulator of p53/TP53 Ndc1_Nup PF09531.10 ORY08308.1 - 5.3 5.6 14.1 0.022 13.5 4.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup IPK PF03770.16 ORY08309.1 - 7.1e-55 185.9 0.0 8.7e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase SpoIIE PF07228.12 ORY08310.1 - 1.3e-13 51.3 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 ORY08310.1 - 3.6e-10 39.9 0.0 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY08310.1 - 1.3e-06 28.2 0.1 2.4e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C POTRA_1 PF08478.10 ORY08310.1 - 0.17 12.2 0.6 0.33 11.3 0.1 1.7 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Trehalase PF01204.18 ORY08311.1 - 1.9e-125 419.6 2.9 7.1e-112 374.8 0.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 ORY08311.1 - 0.0029 16.6 0.5 0.0069 15.4 0.5 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase PTR2 PF00854.21 ORY08312.1 - 3.7e-86 289.4 4.1 5.4e-86 288.9 4.1 1.3 1 0 0 1 1 1 1 POT family MNHE PF01899.16 ORY08312.1 - 9.7 5.9 7.4 1 9.1 0.3 2.7 3 1 0 3 3 3 0 Na+/H+ ion antiporter subunit FAM195 PF14799.6 ORY08313.1 - 0.064 13.6 1.0 0.25 11.7 1.0 1.8 2 0 0 2 2 2 0 FAM195 family ECH_1 PF00378.20 ORY08314.1 - 3.2e-56 190.4 0.0 3.7e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY08314.1 - 1.2e-27 97.3 0.0 1.6e-25 90.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PAXNEB PF05625.11 ORY08314.1 - 0.13 11.4 0.0 0.8 8.8 0.0 1.9 2 0 0 2 2 2 0 PAXNEB protein SH3BGR PF04908.15 ORY08315.1 - 5.8e-20 71.3 0.5 7.5e-20 70.9 0.5 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 ORY08315.1 - 2.4e-09 37.3 0.0 4.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin TF_Zn_Ribbon PF08271.12 ORY08317.1 - 1.3e-06 27.8 2.3 2.7e-06 26.8 2.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 ORY08317.1 - 0.00017 21.6 0.7 0.13 12.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RNA_pol_3_Rpc31 PF11705.8 ORY08317.1 - 0.0068 16.7 0.2 0.011 16.0 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SYF2 PF08231.12 ORY08318.1 - 1e-55 188.5 23.8 1e-55 188.5 23.8 2.1 2 0 0 2 2 2 1 SYF2 splicing factor SecY PF00344.20 ORY08319.1 - 5.8e-69 232.7 12.2 8e-69 232.2 12.2 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY08319.1 - 4.6e-19 68.0 0.2 1.4e-18 66.4 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Tim44 PF04280.15 ORY08320.1 - 6e-24 84.8 0.1 9.2e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 ORY08320.1 - 6.1e-08 32.0 0.1 8.4e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 MBA1-like protein Ribosomal_L32p PF01783.23 ORY08321.1 - 7.6e-17 61.3 9.9 1e-16 60.9 9.9 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family NS3 PF17530.2 ORY08321.1 - 0.072 12.7 0.2 0.089 12.4 0.2 1.1 1 0 0 1 1 1 0 Non-structural protein NS3 Stc1 PF12898.7 ORY08321.1 - 0.073 13.6 3.3 0.097 13.2 3.3 1.1 1 0 0 1 1 1 0 Stc1 domain DUF4798 PF16055.5 ORY08321.1 - 0.089 13.0 1.6 0.12 12.6 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Evr1_Alr PF04777.13 ORY08321.1 - 0.29 11.6 1.9 1.1 9.7 1.9 1.8 1 1 0 1 1 1 0 Erv1 / Alr family Sds3 PF08598.11 ORY08322.1 - 3.5e-08 33.7 18.4 5.9e-08 33.0 16.1 2.0 2 0 0 2 2 2 1 Sds3-like PhaP_Bmeg PF09602.10 ORY08322.1 - 0.0014 18.6 15.7 0.022 14.7 6.1 2.2 1 1 1 2 2 2 2 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FapA PF03961.13 ORY08322.1 - 2.8 6.4 10.2 8.7 4.8 9.4 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A MSC PF09402.10 ORY08322.1 - 8 5.8 10.4 15 4.9 10.4 1.7 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain ADH_N PF08240.12 ORY08385.1 - 2.6e-24 85.2 8.2 4.3e-24 84.5 8.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY08385.1 - 3.3e-20 72.4 0.0 7.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY08385.1 - 8.4e-05 23.6 0.0 0.00015 22.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY08385.1 - 0.0043 16.4 0.2 0.0069 15.7 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 ORY08385.1 - 0.0093 16.8 0.1 0.12 13.2 0.1 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Corona_I PF03187.14 ORY08385.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein 2-Hacid_dh_C PF02826.19 ORY08385.1 - 0.091 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.28 ORY08386.1 - 1.7e-11 44.4 0.0 2.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SF3b1 PF08920.10 ORY08387.1 - 4.6e-44 149.7 6.4 4.6e-44 149.7 6.4 3.1 2 1 1 3 3 2 2 Splicing factor 3B subunit 1 HEAT PF02985.22 ORY08387.1 - 4.9e-11 41.9 7.9 0.14 12.5 0.1 9.3 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 ORY08387.1 - 6.8e-11 42.4 7.8 0.015 15.7 0.1 8.5 6 3 3 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 ORY08387.1 - 6.1e-09 36.2 6.8 0.55 10.8 0.0 7.6 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY08387.1 - 3.3e-06 27.6 2.0 0.14 12.8 0.0 5.0 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY08387.1 - 7.4e-05 21.5 5.6 0.044 12.3 0.1 3.3 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 ORY08387.1 - 0.00027 21.0 8.7 2.7 8.0 0.0 5.9 6 3 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORY08387.1 - 0.0021 17.7 1.8 2.2 7.8 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal NUC173 PF08161.12 ORY08387.1 - 0.0029 17.3 1.1 4 7.0 0.0 4.7 3 1 1 4 4 4 1 NUC173 domain Dopey_N PF04118.14 ORY08387.1 - 0.0058 15.8 2.5 0.19 10.8 0.0 3.8 3 1 1 4 4 4 1 Dopey, N-terminal Arm PF00514.23 ORY08387.1 - 0.0073 16.3 0.4 31 4.8 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 ORY08387.1 - 0.028 14.4 0.2 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Tti2 PF10521.9 ORY08387.1 - 0.087 12.4 0.8 4.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Tti2 family MMS19_C PF12460.8 ORY08387.1 - 0.094 11.8 0.0 9.3 5.2 0.0 3.7 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal PAP2_3 PF14378.6 ORY08388.1 - 6e-22 78.3 8.9 1.1e-21 77.4 8.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 ORY08388.1 - 2.8e-09 36.8 4.3 2.8e-09 36.8 4.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_M48_N PF16491.5 ORY08389.1 - 1.6e-67 227.0 4.7 1.6e-67 227.0 4.7 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORY08389.1 - 2.3e-48 164.6 0.0 3.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ORY08389.1 - 0.02 14.1 3.1 1.4 8.0 0.1 3.1 3 0 0 3 3 3 0 BlaR1 peptidase M56 Peptidase_M43 PF05572.13 ORY08389.1 - 0.091 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A SOR_SNZ PF01680.17 ORY08390.1 - 7.6e-113 375.3 6.4 1.1e-112 374.8 6.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ORY08390.1 - 2e-09 37.2 8.8 1.8e-07 30.7 0.5 2.9 1 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 ORY08390.1 - 0.0001 22.3 0.0 0.00042 20.3 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 ORY08390.1 - 0.00012 21.3 1.3 0.16 11.0 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 ORY08390.1 - 0.0075 15.5 0.3 0.23 10.7 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 ORY08390.1 - 0.012 15.0 0.4 0.34 10.3 0.0 2.6 2 2 0 2 2 2 0 Histidine biosynthesis protein OMPdecase PF00215.24 ORY08390.1 - 0.017 14.8 0.2 0.6 9.7 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IGPS PF00218.21 ORY08390.1 - 0.067 12.4 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF4939 PF16297.5 ORY08391.1 - 1e-10 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF272 PF03312.15 ORY08391.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF272) LPD24 PF18839.1 ORY08391.1 - 0.15 12.3 0.3 0.87 9.9 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Pkinase PF00069.25 ORY08392.1 - 1.1e-70 238.0 0.1 1.6e-70 237.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY08392.1 - 1.9e-51 174.8 0.1 3.1e-51 174.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY08392.1 - 3.4e-21 75.3 0.0 7.5e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORY08392.1 - 4e-14 53.0 0.3 9.3e-14 51.8 0.3 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORY08392.1 - 6.5e-08 32.2 0.0 9.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY08392.1 - 8.2e-06 24.8 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORY08392.1 - 0.0013 19.2 0.7 1 9.8 0.0 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain APH PF01636.23 ORY08392.1 - 0.0019 18.2 0.2 0.042 13.8 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH_9 PF15410.6 ORY08392.1 - 0.0031 17.8 0.1 0.037 14.4 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain RIO1 PF01163.22 ORY08392.1 - 0.0037 16.9 0.2 0.01 15.5 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY08392.1 - 0.022 13.7 1.4 0.049 12.6 1.4 1.4 1 1 0 1 1 1 0 Haspin like kinase domain FA_desaturase PF00487.24 ORY08393.1 - 2e-32 113.0 26.0 6.1e-32 111.4 23.4 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 ORY08393.1 - 2.5e-12 46.8 0.1 4.8e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_U4 PF03419.13 ORY08393.1 - 0.22 10.8 4.2 0.14 11.5 1.4 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Metallophos PF00149.28 ORY08394.1 - 1.1e-36 127.3 0.1 1.4e-36 127.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 ORY08394.1 - 0.054 13.1 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 ORY08394.1 - 0.099 13.1 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HRG PF16954.5 ORY08395.1 - 0.022 15.2 1.9 6.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene MASE1 PF05231.14 ORY08395.1 - 0.73 8.9 7.8 0.32 10.1 1.5 2.0 2 0 0 2 2 2 0 MASE1 His_Phos_1 PF00300.22 ORY08396.1 - 2.9e-41 141.3 0.0 3.5e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Trigger_C PF05698.14 ORY08396.1 - 0.056 13.5 0.2 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus LtuB PF17455.2 ORY08396.1 - 0.071 13.7 0.0 0.39 11.4 0.0 2.1 2 0 0 2 2 2 0 Late transcription unit B RhoGAP PF00620.27 ORY08397.1 - 4.4e-17 62.3 0.0 8.6e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 ORY08397.1 - 2.9e-13 49.9 0.0 4.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PapD-like PF14874.6 ORY08397.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like NDUF_B12 PF08122.12 ORY08398.1 - 1e-21 76.7 0.2 1.1e-21 76.6 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family LTV PF04180.14 ORY08399.1 - 3.1e-78 264.2 38.8 3.6e-54 185.0 11.7 3.1 1 1 2 3 3 3 3 Low temperature viability protein DUF3907 PF13047.6 ORY08399.1 - 0.03 14.3 1.3 0.11 12.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) TMEM119 PF15724.5 ORY08399.1 - 4.2 7.4 7.5 12 5.8 7.5 1.7 1 0 0 1 1 1 0 TMEM119 family Peptidase_M18 PF02127.15 ORY08400.1 - 8.1e-179 594.9 0.2 9.1e-179 594.8 0.2 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORY08400.1 - 5.1e-08 32.3 0.5 4e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Chitin_synth_2 PF03142.15 ORY08401.1 - 3.5e-106 355.9 0.2 4.7e-106 355.5 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 ORY08401.1 - 1.3e-08 34.8 0.0 0.0044 17.1 0.1 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ORY08401.1 - 2e-06 27.8 5.9 6.1e-06 26.3 5.9 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY08401.1 - 2.8e-05 24.0 0.0 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY08401.1 - 5e-05 23.3 0.0 0.0005 20.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY08401.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Proteasome PF00227.26 ORY08402.1 - 2.5e-49 167.4 0.0 3e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY08402.1 - 7.2e-13 48.0 0.0 1.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RhoGEF PF00621.20 ORY08404.1 - 7.2e-32 111.1 0.4 1.8e-31 109.8 0.1 2.0 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.11 ORY08404.1 - 1.3e-30 105.5 0.1 2.7e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 ORY08404.1 - 4.2e-18 65.1 0.3 1.5e-17 63.2 0.3 2.1 1 0 0 1 1 1 1 PB1 domain PH_10 PF15411.6 ORY08404.1 - 1.4e-15 57.7 0.0 4.1e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain MMR_HSR1_C PF08438.10 ORY08404.1 - 0.061 13.9 0.6 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 GTPase of unknown function C-terminal PH PF00169.29 ORY08404.1 - 0.082 13.4 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 PH domain PUF PF00806.19 ORY08406.1 - 1.6e-68 222.7 13.9 2.9e-08 32.9 0.1 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 ORY08406.1 - 0.042 13.7 2.3 9.2 6.1 0.0 4.3 5 0 0 5 5 5 0 Single Cache domain 2 DUF3684 PF12449.8 ORY08409.1 - 8.7e-260 864.9 0.0 1.1e-252 841.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3684) CUE PF02845.16 ORY08409.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 CUE domain HATPase_c_3 PF13589.6 ORY08409.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 ORY08409.1 - 0.14 12.2 1.0 0.25 11.4 1.0 1.3 1 0 0 1 1 1 0 WLM domain RNA_pol_Rpb2_6 PF00562.28 ORY08410.1 - 1e-24 87.3 0.1 1.2e-24 87.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_6 PF00562.28 ORY08411.1 - 2.3e-13 50.0 0.1 2.6e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RAMP4 PF06624.12 ORY08412.1 - 1.3e-17 63.6 0.0 1.4e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 RNA_pol PF00940.19 ORY08413.1 - 2.2e-182 606.5 0.0 3e-182 606.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 ORY08413.1 - 3.8e-80 269.8 0.1 3.8e-80 269.8 0.1 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 ORY08413.1 - 4e-08 33.3 0.0 2.3e-06 27.7 0.0 2.9 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.7 ORY08413.1 - 0.0036 17.0 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 PPR repeat PPR PF01535.20 ORY08413.1 - 0.053 13.8 0.0 29 5.2 0.0 3.4 3 0 0 3 3 3 0 PPR repeat DUF3335 PF11814.8 ORY08413.1 - 0.16 11.4 0.0 0.42 10.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase_C39 like family CDC27 PF09507.10 ORY08414.1 - 3.2e-48 165.2 35.3 2.4e-23 83.2 13.6 2.3 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Joubert PF15392.6 ORY08414.1 - 1.4 8.6 11.5 0.12 12.0 6.5 1.8 1 1 1 2 2 2 0 Joubert syndrome-associated TBP PF00352.21 ORY08415.1 - 2e-68 226.3 0.1 2e-33 114.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ORY08415.1 - 4.7e-05 23.4 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 ORY08415.1 - 0.063 13.1 0.0 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) tRNA-synt_1c PF00749.21 ORY08416.1 - 1.4e-109 365.8 0.0 1.8e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF1016_N PF17761.1 ORY08416.1 - 0.18 12.0 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 DUF1016 N-terminal domain PWI PF01480.17 ORY08417.1 - 4.2e-05 23.8 0.3 7.7e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 PWI domain DUF3730 PF12530.8 ORY08417.1 - 0.0043 16.6 0.0 0.0064 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 ORY08417.1 - 0.034 14.5 0.1 0.064 13.6 0.1 1.4 1 0 0 1 1 1 0 HEAT repeats Zn_ribbon_2 PF12674.7 ORY08417.1 - 0.34 11.6 1.2 2 9.1 0.3 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain Zn-C2H2_12 PF18112.1 ORY08417.1 - 7.5 7.1 7.2 1.7 9.2 0.4 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain 2Fe-2S_thioredx PF01257.19 ORY08418.1 - 9.2e-61 203.9 0.2 1.1e-60 203.6 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin POT1 PF02765.17 ORY08418.1 - 0.033 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 CMAS PF02353.20 ORY08419.1 - 6.2e-10 38.8 0.0 8.2e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY08419.1 - 3.8e-07 30.7 0.0 6.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY08419.1 - 1.2e-05 25.3 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY08419.1 - 0.0014 19.3 0.0 0.0021 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY08419.1 - 0.0019 18.8 0.0 0.0035 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY08419.1 - 0.0037 16.6 0.0 0.0067 15.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 ORY08419.1 - 0.0091 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ORY08419.1 - 0.079 14.0 0.1 0.15 13.1 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Orn_Arg_deC_N PF02784.16 ORY08419.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Redoxin PF08534.10 ORY08420.1 - 1.1e-36 125.7 0.0 1.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY08420.1 - 1.2e-11 44.6 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Methyltransf_28 PF02636.17 ORY08422.1 - 3.8e-39 134.9 0.0 5.4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 ORY08422.1 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 ORY08422.1 - 0.065 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ORY08422.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Adap_comp_sub PF00928.21 ORY08424.1 - 3.2e-89 298.8 0.0 4.3e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY08424.1 - 1.7e-08 34.5 1.4 2.8e-08 33.8 1.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 ORY08424.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 ORY08424.1 - 0.027 14.5 0.1 0.074 13.1 0.1 1.7 1 0 0 1 1 1 0 Regulated-SNARE-like domain SRP-alpha_N PF04086.13 ORY08425.1 - 2.2e-47 162.4 16.9 1.9e-46 159.3 16.9 2.0 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 ORY08425.1 - 1.1e-45 155.6 0.3 1.4e-26 93.3 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP54_N PF02881.19 ORY08425.1 - 1.8e-12 47.3 0.1 7.1e-12 45.4 0.1 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 ORY08425.1 - 0.00065 18.8 0.0 0.075 12.0 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ORY08425.1 - 0.0057 17.1 0.0 0.033 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ORY08425.1 - 0.0058 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORY08425.1 - 0.013 15.5 0.3 0.17 12.0 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 ORY08425.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY08425.1 - 0.017 15.0 0.1 0.049 13.6 0.0 1.8 2 0 0 2 2 2 0 NTPase Fer4_NifH PF00142.18 ORY08425.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CODH_A_N PF18537.1 ORY08425.1 - 0.071 13.1 0.2 0.45 10.6 0.0 2.4 2 1 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain MMR_HSR1 PF01926.23 ORY08425.1 - 0.23 11.5 3.4 1.6 8.8 1.5 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase PGM_PMM_I PF02878.16 ORY08426.1 - 8.7e-17 61.1 0.1 1.9e-07 30.9 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 ORY08426.1 - 1.1e-12 47.9 0.2 6e-12 45.6 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 ORY08426.1 - 0.00027 21.5 0.6 0.0022 18.6 0.2 2.8 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ORY08426.1 - 0.056 13.7 0.6 0.18 12.0 0.6 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Mito_carr PF00153.27 ORY08428.1 - 8.6e-69 227.5 1.3 7.2e-25 86.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NPR3 PF03666.13 ORY08430.1 - 5.4e-99 332.1 8.1 6.7e-88 295.5 6.7 2.1 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 ORY08430.1 - 5.9e-05 22.0 0.4 0.11 11.3 0.6 2.8 2 1 0 2 2 2 2 Nitrogen permease regulator 2 Rad51 PF08423.11 ORY08431.1 - 5.4e-22 78.3 0.0 5.9e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 ORY08431.1 - 2.2e-08 33.7 0.1 1.5e-07 31.0 0.1 2.0 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 ORY08431.1 - 3.2e-07 30.3 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 ORY08431.1 - 2e-05 24.1 0.0 0.00021 20.7 0.0 2.0 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 ORY08431.1 - 0.00022 20.8 0.0 0.0046 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 ORY08431.1 - 0.00043 19.8 0.2 0.0012 18.3 0.2 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_18 PF13238.6 ORY08431.1 - 0.00079 20.0 0.1 0.0022 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORY08431.1 - 0.0028 18.1 0.1 0.015 15.8 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY08431.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ORY08431.1 - 0.0084 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY08431.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY08431.1 - 0.012 15.4 0.0 0.15 11.8 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 ORY08431.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 ORY08431.1 - 0.028 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 ORY08431.1 - 0.038 13.8 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY08431.1 - 0.041 13.3 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 ORY08431.1 - 0.044 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY08431.1 - 0.054 13.6 0.0 0.098 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY08431.1 - 0.091 13.1 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 ORY08431.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 ORY08431.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Agglutinin_C PF18021.1 ORY08431.1 - 0.15 12.6 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Agglutinin C-terminal TetR_C_37 PF18665.1 ORY08432.1 - 0.075 13.6 0.5 7.7 7.2 0.0 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HEAT_2 PF13646.6 ORY08432.1 - 0.32 11.4 1.6 2 8.8 0.3 3.0 3 0 0 3 3 3 0 HEAT repeats F-box PF00646.33 ORY08432.1 - 0.36 10.8 4.0 0.3 11.0 0.3 2.8 3 0 0 3 3 3 0 F-box domain DUF2046 PF09755.9 ORY08433.1 - 1.1e-41 143.0 39.6 1.8e-30 106.2 25.7 2.5 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) MAD PF05557.13 ORY08433.1 - 3 6.1 36.6 0.59 8.4 17.0 3.0 2 1 1 3 3 3 0 Mitotic checkpoint protein Mu-like_Pro PF10123.9 ORY08433.1 - 4.7 6.7 12.3 3.9 6.9 8.7 2.0 2 0 0 2 2 2 0 Mu-like prophage I protein Tfb4 PF03850.14 ORY08434.1 - 1.2e-67 228.3 13.1 1.3e-44 152.8 0.1 2.1 1 1 1 2 2 2 2 Transcription factor Tfb4 DUF4183 PF13799.6 ORY08434.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) Fcf1 PF04900.12 ORY08435.1 - 4.4e-40 136.1 2.7 7.1e-40 135.4 2.7 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 ORY08435.1 - 3.7e-11 43.3 0.0 8.7e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 PIN like domain YqzE PF14038.6 ORY08435.1 - 0.36 10.9 2.2 0.75 9.8 2.2 1.5 1 0 0 1 1 1 0 YqzE-like protein FH2 PF02181.23 ORY08436.1 - 9.5e-87 291.5 10.6 9.5e-87 291.5 10.6 3.1 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORY08436.1 - 1.3e-36 126.1 0.5 1.3e-36 126.1 0.5 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 ORY08436.1 - 5.6e-31 107.6 0.3 5.6e-31 107.6 0.3 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Coat_F PF07875.12 ORY08436.1 - 0.11 12.7 1.2 0.52 10.6 1.2 2.2 1 0 0 1 1 1 0 Coat F domain DUF5320 PF17253.2 ORY08436.1 - 0.16 13.1 0.8 52 5.0 1.4 3.3 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Bestrophin PF01062.21 ORY08437.1 - 9e-50 169.7 0.9 1.2e-49 169.3 0.9 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel AsnA PF03590.15 ORY08437.1 - 0.003 17.4 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Aspartate-ammonia ligase Glyoxalase PF00903.25 ORY08438.1 - 3.5e-12 46.6 0.4 2.9e-10 40.4 0.4 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORY08438.1 - 0.00051 20.0 0.2 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ORY08438.1 - 0.032 14.5 0.0 1 9.7 0.0 2.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY08438.1 - 0.11 13.2 0.0 0.16 12.7 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain RdRP PF05183.12 ORY08439.1 - 6.9e-59 200.0 0.0 1e-58 199.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sulfotransfer_1 PF00685.27 ORY08440.1 - 0.063 12.7 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain 2-Hacid_dh_C PF02826.19 ORY08440.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1016_N PF17761.1 ORY08441.1 - 0.02 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 DUF1016 N-terminal domain ATP_bind_2 PF03668.15 ORY08442.1 - 0.019 14.2 0.3 0.53 9.5 0.1 2.2 2 0 0 2 2 2 0 P-loop ATPase protein family IL3 PF02059.15 ORY08442.1 - 2 8.5 0.0 2 8.5 0.0 3.1 3 1 1 4 4 4 0 Interleukin-3 Peptidase_M74 PF03411.13 ORY08443.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Basidiobolus_meristosporus_CBS_931.73-Basme2finSC/GCA_002104905.1_Basme2finSC_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Basidiobolus_meristosporus_CBS_931.73-Basme2finSC/GCA_002104905.1_Basme2finSC_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Basidiobolus_meristosporus_CBS_931.73-Basme2finSC/GCA_002104905.1_Basme2finSC_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Basidiobolus_meristosporus_CBS_931.73-Basme2finSC/GCA_002104905.1_Basme2finSC_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 16:02:26 2019 # [ok]